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Search of human proteins with 133922600
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
(674 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 1337 0.0
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 125 1e-28
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 123 6e-28
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 116 6e-26
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 110 3e-24
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 96 1e-19
gi|46309849 hypothetical protein LOC57035 [Homo sapiens] 92 1e-18
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 91 3e-18
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 91 3e-18
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 90 6e-18
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 89 2e-17
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 89 2e-17
gi|50962882 G patch domain containing 8 [Homo sapiens] 88 3e-17
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 87 4e-17
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 87 4e-17
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 87 7e-17
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 86 9e-17
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 86 1e-16
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 84 3e-16
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 84 3e-16
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 84 3e-16
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 84 4e-16
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 84 4e-16
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 84 4e-16
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 84 6e-16
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 84 6e-16
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 83 9e-16
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 83 9e-16
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 82 2e-15
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 81 3e-15
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 1337 bits (3460), Expect = 0.0
Identities = 674/674 (100%), Positives = 674/674 (100%)
Query: 1 MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAA 60
MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAA
Sbjct: 1 MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAA 60
Query: 61 ESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLTTISPEQESDERKCNYERYRGLV 120
ESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLTTISPEQESDERKCNYERYRGLV
Sbjct: 61 ESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLTTISPEQESDERKCNYERYRGLV 120
Query: 121 QNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKAAE 180
QNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKAAE
Sbjct: 121 QNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKAAE 180
Query: 181 KPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLR 240
KPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLR
Sbjct: 181 KPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLR 240
Query: 241 KDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPY 300
KDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPY
Sbjct: 241 KDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPY 300
Query: 301 KRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPP 360
KRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPP
Sbjct: 301 KRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPP 360
Query: 361 QPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSR 420
QPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSR
Sbjct: 361 QPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSR 420
Query: 421 SWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYR 480
SWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYR
Sbjct: 421 SWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYR 480
Query: 481 RGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREK 540
RGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREK
Sbjct: 481 RGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREK 540
Query: 541 LTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEK 600
LTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEK
Sbjct: 541 LTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEK 600
Query: 601 MIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSR 660
MIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSR
Sbjct: 601 MIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSR 660
Query: 661 RRSRSRSRSPHYRH 674
RRSRSRSRSPHYRH
Sbjct: 661 RRSRSRSRSPHYRH 674
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 125 bits (315), Expect = 1e-28
Identities = 143/495 (28%), Positives = 199/495 (40%), Gaps = 65/495 (13%)
Query: 201 IPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKA 260
IP +E+ +E+ Q Q+ + D D ++DKEE E
Sbjct: 119 IPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKD-----KRDKEEKE------------- 160
Query: 261 MYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE-SRSRSRSPT 319
S R++RE R + R RK PS RR SP KRS S S ++SRS SP
Sbjct: 161 ------SSREKRE-RSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213
Query: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSS 379
P ++EK + +E + A + + + KP P+P P+P +N S
Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKN------SKK 267
Query: 380 SSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRG 439
S SRS SRS +RS R + R R RSRSRS+S R S R S R
Sbjct: 268 EKEKEKTRPRSRSRSKSRSRTRS-RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
Query: 440 RRHSGGGSRDGHRYSRSPARRGGYGPRRRS------RSRSHSGDRYRRGGRGLRHHSSSR 493
HR SRSP RR RRRS S S S R R + +SS
Sbjct: 327 TPPRRMPPPPRHRRSRSPVRR-----RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
Query: 494 SRSSWSLSPSRSRSLTRSR-----------SHSPSPSQSRSRSRSR-SQSP---SPSPAR 538
R + LSPS S R R HSP+P QS +SR S SP S +
Sbjct: 382 PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTK 441
Query: 539 EKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQ 598
K T SP+ K +K E + +E K + + R + N+Q +D ++
Sbjct: 442 HKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR-RQYRRQNQQSSSDSGSSS 500
Query: 599 EKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSS 658
++ + E+ R + ++R++ R+ RSPSP +R
Sbjct: 501 SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTR---- 556
Query: 659 SRRRSRSRSRSPHYR 673
RRRS S + P R
Sbjct: 557 -RRRSPSPAPPPRRR 570
Score = 80.9 bits (198), Expect = 4e-15
Identities = 132/550 (24%), Positives = 205/550 (37%), Gaps = 74/550 (13%)
Query: 148 PSEDEKKKLAE--------KKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDE 199
P+ ++K+K E K+ S+ S + +V K PE +E + E+ S ++++
Sbjct: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK 271
Query: 200 VIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEK 259
E + + +K + R R+ + + +
Sbjct: 272 ------------EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS----------- 308
Query: 260 AMYSGRR--SRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPS---ESSSESRSR 314
YS RR S R+R R + R PP + R SP + S S SSS S SR
Sbjct: 309 --YSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366
Query: 315 SRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPG---GPAPGRNA 371
SRSP P + K T + + +A+ PPA P P P P ++
Sbjct: 367 SRSP-PKKPPKRTS----SPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSN 421
Query: 372 SARRRSSSSSSSSSASRTSSSRSSSRSSSRS---RRGGGYYRSGRHARSRSRSWSRSRSR 428
R+ S S ++ + + + + + S S + + + + S +
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQ 481
Query: 429 SRRYSRSRSRGRRHSGGGSR-DGHRYSRSPARRGGYGPRRR-SRSRSHSGDRYRRGGRGL 486
R+Y R + SG S + R RS + G G RRR S SRS S +R
Sbjct: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKR----- 536
Query: 487 RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS---RSQSPSPSPAREKLTR 543
+ +S R R S SP +R R RS SP+P R R+ + R ++PSP P R +
Sbjct: 537 QKETSPRGRRRRSPSPPPTR---RRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
Query: 544 PAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQ 603
SP + + + P K A+ P P K + R+ Q +
Sbjct: 594 RRYSPPIQRRYSPSPPP--KRRTASPP---PPPKRRASPSPPPKRRVSHSPPPKQ----R 644
Query: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS 663
+ R L + RK R RE + + R S SP PR + SS
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK---RHSPSPRPRAPQTSSSPPPVR 701
Query: 664 RSRSRSPHYR 673
R S SP R
Sbjct: 702 RGASSSPQRR 711
Score = 78.2 bits (191), Expect = 2e-14
Identities = 116/496 (23%), Positives = 181/496 (36%), Gaps = 95/496 (19%)
Query: 148 PSEDEKKKLAEKKASIGYT------YEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVI 201
P + + + + S G T ++ + E A KP + E + EE +
Sbjct: 417 PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA 476
Query: 202 PDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAM 261
+ NQ+ +D +++ + R R + E + + A
Sbjct: 477 DSVQQRRQYRRQNQQSSSDSGSSSSS------EDERPKRSHVKNGEVGRRRRHSPSRSAS 530
Query: 262 YSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPG 321
S R++++E + R R SPP RR SP+ P R + R R+ SP P
Sbjct: 531 PS---PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR 587
Query: 322 REEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSS 381
R + S + + T PP P + P+P +RR S S
Sbjct: 588 RRSP----SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP----PPKRRVSHSP 639
Query: 382 SSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRR 441
S + R S SS+ R+G S SRS R +RS +R
Sbjct: 640 PPKQRSSPVTKRRSPSLSSKHRKGS------------------SPSRSTREARSPQPNKR 681
Query: 442 HSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLS 501
HS PR R+ S S RRG SS + R S S S
Sbjct: 682 HSP-------------------SPRPRAPQTSSSPPPVRRGA-----SSSPQRRQSPSPS 717
Query: 502 PSRSRSLTRS-------RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAA-------- 546
R ++R+ ++ SPSP R S SRS S SP PA +K P +
Sbjct: 718 TRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
Query: 547 ---SPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQ 603
SPAV K K+ + + P+ + QE + +K +++ K DKK
Sbjct: 778 TNWSPAVPVKKAKSPTPS-----PSPPRNSDQEGGGKKKKKKKDKKHKKDKK-------H 825
Query: 604 QEHERQEREDELRAMA 619
++H++ ++E + A A
Sbjct: 826 KKHKKHKKEKAVAAAA 841
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/213 (24%), Positives = 76/213 (35%), Gaps = 66/213 (30%)
Query: 466 RRRSRSRSHSGDRYRRGGRGLRHHSSS-RSRSSWSLSPSRSRSLTR---SRSHSPSPSQS 521
+++ + + R R S S R R S S SP R S R RSHS SP
Sbjct: 145 KKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP--- 201
Query: 522 RSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLR 581
R R++S+SPSP+P +++ T P+V K + A PK P
Sbjct: 202 --RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP------- 252
Query: 582 MQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQY 641
K+ + EK ++EKE+E+
Sbjct: 253 --------IPEPKEPSPEK--------------------------NSKKEKEKEK----- 273
Query: 642 SRQSRSPSPRYSREYSSSRRRSRSRSRSPHYRH 674
+R S SR +SRSR+RS H
Sbjct: 274 -----------TRPRSRSRSKSRSRTRSRSPSH 295
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 123 bits (308), Expect = 6e-28
Identities = 129/411 (31%), Positives = 190/411 (46%), Gaps = 65/411 (15%)
Query: 287 PSYARRDSPT-----YDPYKRSPSESSSESRSRSRSPTPGRE--EKITFITSFGGSDEEA 339
PS + SPT Y ++ + S +S S+SRSP R +K T S +
Sbjct: 251 PSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRN 310
Query: 340 AAAAAAAAASGVTT-----------GKPPAPPQPGGPAPGRNAS-----ARRRSSSSSSS 383
+ A + G+ + K + Q P GR+ + ++ RS S S S
Sbjct: 311 HSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRS 370
Query: 384 SSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHS 443
SS R SS R S + G + H+RSRS + +R RSRSR ++R R R S
Sbjct: 371 SSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS 430
Query: 444 GGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPS 503
+RD R SRSP Y R RSRSRS + R HS SRS + + S
Sbjct: 431 PNKARDCSR-SRSP-----YKARDRSRSRSPN---------KARDHSRSRSPNK-ARDRS 474
Query: 504 RSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGK 563
RSRS ++ R HS S S+ R RS+SPS +E+ R + S + K
Sbjct: 475 RSRSPSKERDHSQLGSPSKERDHRRSRSPS----KERQCRQSRS-------------SSK 517
Query: 564 ETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIR 623
E + + +P ++ + R ++ N++ D+ ++ ++EH RQ R R+ R
Sbjct: 518 ERDHRRSR-SPSKERQRRQSRSPNKE--RDRSQSRSPSEEREH-RQSRSPSKERDRRRWR 573
Query: 624 --MKERERREKEREEWERQYSRQSRSPSPR--YSREYSSSRRRSRSRSRSP 670
KERERR+ ER +SR SRSP+ + YSR +SS+ ++ SRSR+P
Sbjct: 574 SPSKERERRQSRSSSEERDHSR-SRSPNKQSGYSRPRASSKEKAHSRSRTP 623
Score = 116 bits (291), Expect = 6e-26
Identities = 135/459 (29%), Positives = 206/459 (44%), Gaps = 87/459 (18%)
Query: 265 RRSRRQRREFREKRLRGRKISPP---------------SYARRDSPTYDPYKR---SPSE 306
R S R+R + + + L + PP S A+ +PT P K +PS
Sbjct: 177 RTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSP 236
Query: 307 SSSES-RSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGP 365
SSS +S + P RE+ S+ ++ + + A+ T +P + Q P
Sbjct: 237 SSSRKVKSYGQMIIPSREK------SYSPTEMSSRVKSYNQAS---TRSRPQSHSQSRSP 287
Query: 366 APGRNASARRRSSSSSSSSSASRTSSSRSSSR----------SSSRSR-RGGGYYRSGRH 414
R+ S +R S S S S +RS +R S SRS +G +S
Sbjct: 288 RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP 347
Query: 415 ARSRSRSWSR--SRSRSRRYSRSRSRGRRHSGGGS---RDGHRYSRSPARRGGYGPRR-- 467
R RS +WSR S+ RS +SRS S+ R H G S G S SP ++ + R
Sbjct: 348 RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSP 407
Query: 468 ---RSRSRSHSGDRYRRGGRGLRHHSS---SRSRSSWSLSP-SRSRSLTRSRSHSPSPSQ 520
R RSRS S + R R + + SRSRS + SRSRS ++R HS S S
Sbjct: 408 NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP 467
Query: 521 SRSRSRSRSQSPSP--------SPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKL 572
+++R RSRS+SPS SP++E+ R + SP+ + +++ ++ KE + +
Sbjct: 468 NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR-SSSKERDHRRSR- 525
Query: 573 TPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREK 632
+P ++ + R ++ N++ D+ ++ ++EH RQ R KER+RR
Sbjct: 526 SPSKERQRRQSRSPNKE--RDRSQSRSPSEEREH-RQSRSPS----------KERDRRRW 572
Query: 633 EREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPH 671
ER+ RQSRS SS R SRSRSP+
Sbjct: 573 RSPSKERE-RRQSRS----------SSEERDHSRSRSPN 600
Score = 110 bits (275), Expect = 4e-24
Identities = 127/451 (28%), Positives = 188/451 (41%), Gaps = 62/451 (13%)
Query: 264 GRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRS-----PSESSSESRSRSRSP 318
G SR + ++K RG+ P + R+ P S P S RS +
Sbjct: 153 GMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAV 212
Query: 319 TPGRE--EKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRR 376
TP + T I S SD + +++ + G Q P+ ++ S
Sbjct: 213 TPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYG----------QMIIPSREKSYSPTEM 262
Query: 377 SSSSSSSSSASRTS--SSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSR 434
SS S + AS S S S SRS RSR G + H+R RS SW R+ SR+R +R
Sbjct: 263 SSRVKSYNQASTRSRPQSHSQSRSPRRSRSGS---QKRTHSRVRSHSWKRNHSRARSRTR 319
Query: 435 S--------RSRGRRHSGGGSRDGHRYSRSPAR-RGGYGPRRRSRSRSHSGDRYRRGGRG 485
S+ R HS G S++ SR+P R R R S+ RSHS R R
Sbjct: 320 KGILSQMGRHSQSRSHSKGKSQN---QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD 376
Query: 486 LRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS------RSQSPSPSPARE 539
R SS R S S S S ++ SRS SP+ ++ RSRSRS RS+S SP+ AR+
Sbjct: 377 HRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
Query: 540 KLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQK-----------ALNR 588
+R + ++ + P ++ ++ +++ + R + R
Sbjct: 437 -CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKER 495
Query: 589 QFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSP 648
+ + ++E+ +Q + D R+ + KER+RR+ ER S QSRSP
Sbjct: 496 DHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS---KERQRRQSRSPNKERDRS-QSRSP 551
Query: 649 SPRYSREYSSS------RRRSRSRSRSPHYR 673
S S S RRR RS S+ R
Sbjct: 552 SEEREHRQSRSPSKERDRRRWRSPSKERERR 582
Score = 93.2 bits (230), Expect = 7e-19
Identities = 102/383 (26%), Positives = 170/383 (44%), Gaps = 39/383 (10%)
Query: 301 KRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKP---- 356
KRSPS +S+ R R+ PG ++ TS + + + +P
Sbjct: 133 KRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLS 192
Query: 357 -PAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
+ PGG GR++ S++ + S +S + S S SR+ Y + +
Sbjct: 193 KKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS 252
Query: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR-RGGYGPRRRSRSRSH 474
R +S S + SR + Y+++ +R R S H SRSP R R G R SR RSH
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQS-------HSQSRSPRRSRSGSQKRTHSRVRSH 305
Query: 475 SGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRS--RSRSQSP 532
S R +HS +RSR+ + R ++SRSHS SQ++SR+ R RS +
Sbjct: 306 SWKR---------NHSRARSRTRKGILSQMGRH-SQSRSHSKGKSQNQSRTPRRGRSHNW 355
Query: 533 SPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKA 592
S +P++E+ + S + E+ + + KE+G ++ +P ++ ++ N+
Sbjct: 356 SRNPSKERSHSHSRSSSK-ERDHRGSSSPRKESGRSQSG-SPNKQRDHSRSRSPNKA--R 411
Query: 593 DKKAAQEKMIQQEHERQEREDELRAMAR-KIRMKERERREKEREEWERQYSRQSRSPSPR 651
D+ ++ ++ R ++ R +R + K R+R R +SR SRSP+
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSR-SRSPN-- 468
Query: 652 YSREYSSSRRRSRSRSRSPHYRH 674
+R RSRSRS S H
Sbjct: 469 ------KARDRSRSRSPSKERDH 485
Score = 92.8 bits (229), Expect = 9e-19
Identities = 111/349 (31%), Positives = 155/349 (44%), Gaps = 49/349 (14%)
Query: 258 EKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRS 317
+K +S RS +R R R RK R + +S S S +S+++SR+
Sbjct: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGR--------HSQSRSHSKGKSQNQSRT 346
Query: 318 PTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTG-KPPAPPQPGGPAPGRNAS---- 372
P GR + S S + +++ G ++ K Q G P R+ S
Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRS 406
Query: 373 ---ARRRSSSSSSSSSASRTSS-SRSSSRSSSRSR-----RGGGYYRSGRHARSRSRSWS 423
AR RS S S + R+ S S + +R SRSR R RS AR SRS S
Sbjct: 407 PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRS 466
Query: 424 RSRSRSRRYSRSRSRGRRHSGGGS----RDGHRYSRSPAR-------RGGYGPRRRSRSR 472
+++R R SRS S+ R HS GS RD HR SRSP++ R R RSR
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERD-HRRSRSPSKERQCRQSRSSSKERDHRRSR 525
Query: 473 SHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSP 532
S S +R RR R + R RS S SPS R +SR SPS+ R R R R
Sbjct: 526 SPSKERQRRQSRS---PNKERDRSQ-SRSPSEEREHRQSR----SPSKERDRRRWR---- 573
Query: 533 SPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLR 581
SPS RE+ ++S E+ + K++G ++P+ + +EK R
Sbjct: 574 SPSKERERRQSRSSSE---ERDHSRSRSPNKQSGYSRPRASSKEKAHSR 619
Score = 92.8 bits (229), Expect = 9e-19
Identities = 95/327 (29%), Positives = 138/327 (42%), Gaps = 22/327 (6%)
Query: 251 HAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYK-----RSPS 305
H+++ KA R R + R + R R R SP + AR S + PYK RS S
Sbjct: 401 HSRSRSPNKA-----RDRSRSRSPYKARDRSRSRSP-NKARDCSRSRSPYKARDRSRSRS 454
Query: 306 ESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGP 365
+ + SRSRSP R+ + S + + + + + + P+ +
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPS---KERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
Query: 366 APGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRS 425
+ + R S S S R S S + R S+SR H +SRS S R
Sbjct: 512 SRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS---EEREHRQSRSPSKERD 568
Query: 426 RSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYG-PRRRSRSRSHSGDRY--RRG 482
R R R S+ R R + S RD H SRSP ++ GY PR S+ ++HS R + G
Sbjct: 569 RRRWRSPSKERERRQSRSSSEERD-HSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEG 627
Query: 483 GRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLT 542
SS S S S P RS RS + + S SQ+R+ S++ S SPS P+ +
Sbjct: 628 NHSQSRTSSKESDPSQSTVP-RSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTL 686
Query: 543 RPAASPAVGEKLKKTEPAAGKETGAAK 569
S A K T P + ++K
Sbjct: 687 SQDDSQADATTSKATLPGERSSSSSSK 713
Score = 91.3 bits (225), Expect = 3e-18
Identities = 99/381 (25%), Positives = 152/381 (39%), Gaps = 31/381 (8%)
Query: 319 TPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSS 378
+P R K + + GS A A+ + P P PA RN+ SS
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
Query: 379 SSSSSSSASRTSSSRSSSRS--SSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
S+ S+S R S+R SSRS S++R R +++ S R R +SR R
Sbjct: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGR 122
Query: 437 SRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL---------- 486
+ GRR S R R S +P R +G R SR + ++G RG
Sbjct: 123 TPGRRGSRSSKRSPSRAS-TPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
Query: 487 -RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSR------SRSRSQSPSPSPARE 539
R S R+ S S P + RS + +PS ++ + S+ +S +PSPS +R+
Sbjct: 182 ERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
Query: 540 -KLTRPAASPAVGEKLKKTEPAAG-KETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAA 597
K P+ + TE ++ K A + PQ + R + R +K
Sbjct: 242 VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPR---RSRSGSQKRT 298
Query: 598 QEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSP----SPRYS 653
++ + H + R+ RK + + R + R + + QSR+P S +S
Sbjct: 299 HSRV--RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWS 356
Query: 654 REYSSSRRRSRSRSRSPHYRH 674
R S R S SRS S H
Sbjct: 357 RNPSKERSHSHSRSSSKERDH 377
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 116 bits (291), Expect = 6e-26
Identities = 130/449 (28%), Positives = 193/449 (42%), Gaps = 82/449 (18%)
Query: 264 GRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGRE 323
GR R + R GR SP + R S + P KR S S S RSRS
Sbjct: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS------ 518
Query: 324 EKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSS 383
A + S G+ +P +PG + RN R RS S+
Sbjct: 519 -----------------AQRWGRSRSPQRRGRSRSPQRPGW-SRSRNTQRRGRSRSARRG 560
Query: 384 SSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSR---RYSRSRSR-- 438
S SR+ ++R SRS + +RRG R+ RSRSR+ +R RSRSR R RSRSR
Sbjct: 561 RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Query: 439 ------------------------GRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSH 474
GR S +R G SR+PARRG RSRSR+
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRG------RSRSRTP 674
Query: 475 SGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRS-----RSHSPSPSQSRSRSRSRS 529
+ RR GR R + +R S S +P R RS +RS RSHS +P Q R RS S S
Sbjct: 675 A----RRSGRS-RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP-QRRGRSGSSS 728
Query: 530 QSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQ 589
+ + S ++ +R +SP ++KK+ ++ + + P+ + +L LR ++L+
Sbjct: 729 ERKNKSRTSQRRSRSNSSP----EMKKSRISSRRSRSLSSPRSKAKSRLSLR--RSLSGS 782
Query: 590 FKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPS 649
K+ +Q + + + + R R+ R +++ + RQ S S SP
Sbjct: 783 SPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ-SHSSSSPH 841
Query: 650 PRYS-----REYSSSRRRSRSRSRSPHYR 673
P+ R+ S + ++ +S +P R
Sbjct: 842 PKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Score = 114 bits (285), Expect = 3e-25
Identities = 146/479 (30%), Positives = 205/479 (42%), Gaps = 73/479 (15%)
Query: 241 KDKEEA--EAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPP-SYARRDSPTY 297
KDK A A + + E KA RR R K GR SP S + SP +
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK---GRGPSPEGSSSTESSPEH 1661
Query: 298 DPYKRSP---SESSSESRSRSRSPTPGREEKIT-FITSFGGSDEEAAAAAAAAAASGVTT 353
P R+ S SS E +++SR+P R + + +T + +A+++ T
Sbjct: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP 1721
Query: 354 GKPPAPPQPGGPAPGRNA--SARRRSSSSSSSSSASRTSSS-----RSSSRSSSRSRRGG 406
+ P P P + S RRRS+SS + + SR S R RS SRSRR
Sbjct: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR-- 1779
Query: 407 GYYRSGRHARSRSRSWS-RSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGY-- 463
R R R RS S +S SR R+ SRSRSR R GGS G+ +SRSPAR+
Sbjct: 1780 ---EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS--GY-HSRSPARQESSRT 1833
Query: 464 -GPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSS---WSLSPSRSRSLTRSRSHSPSPS 519
RRR RSR+ R R SRSR+S W S SR+ T RS S +P
Sbjct: 1834 SSRRRRGRSRTPPTSRKR-----------SRSRTSPAPWKRSRSRASPATHRRSRSRTPL 1882
Query: 520 QSRSRSRSRS------QSPSPSPAREKLTRPAASPAVGEKLK-KTEPAAGKETGAAKPKL 572
SR RSRSR+ +S S + + +R ASP + + +T P + + + P
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP-- 1940
Query: 573 TPQEKLKLRMQKALNRQFKAD-------KKAAQEKMIQQEHERQEREDELRAMARK---- 621
T + + + R R+ ++ + ++ I + R R +R
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 622 -IRMKERER-----REKEREEWERQYSRQSRSPSPRYSREYSSSRR----RSRSRSRSP 670
R + R R R + R R+SRS +P R+ S SR R RSRSR+P
Sbjct: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059
Score = 111 bits (278), Expect = 2e-24
Identities = 123/414 (29%), Positives = 181/414 (43%), Gaps = 52/414 (12%)
Query: 284 ISPPSYARRDSPTYDPYK-RSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAA 342
++PPS A SPT D +SP + S S S P+P + T ++ S E+
Sbjct: 391 VNPPSEA---SPTRDRSPPKSPEKLPQSSSSESSPPSP----QPTKVSRHASSSPESPKP 443
Query: 343 AAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRS 402
A A + + P + + G A + + + S S S ++ R SRS + +
Sbjct: 444 APAPGSHREISSSPTSKNRSHGRA--KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501
Query: 403 RRGGGYYRSGRHARSRSRSWSRSRSRSR-------------------RYSRSRSRGRRHS 443
+RG H+RSRS W RSRS R +SRSR+ RR
Sbjct: 502 KRG--------HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
Query: 444 GGGSRDGHRYSRSPARRG---GYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSL 500
+R G +SRSPA RG P RR RSRS + R RR SRSR+
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR-RRSRSRTPTRRRSRSRTPARR 612
Query: 501 SPSRSRSLTRSRSHSPSPSQSRSRSRS----RSQSPSPSPAREKLTRPAASPAVGEKLKK 556
SRSR+ R RS + SP + RSRSRS +S S +PAR +R + +PA + +
Sbjct: 613 GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSR-SRTPARRGRSRS 671
Query: 557 TEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELR 616
PA + +G ++ + TP + + R + + ++ + + + +R+ R
Sbjct: 672 RTPA--RRSGRSRSR-TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728
Query: 617 AMARKIRMKERERREKEREEWE--RQYSRQSRS-PSPRYSREYSSSRRRSRSRS 667
K R +R R E + R SR+SRS SPR + S RRS S S
Sbjct: 729 ERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGS 782
Score = 105 bits (261), Expect = 2e-22
Identities = 131/465 (28%), Positives = 186/465 (40%), Gaps = 96/465 (20%)
Query: 265 RRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSP-----T 319
R +RR R E + + R +PP RR S P + S SRS S SP T
Sbjct: 1666 RTARRGSRSSPEPKTKSR--TPP---RRRSSRSSPELTRKARLSRRSRSASSSPETRSRT 1720
Query: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTT-----GKPPAPPQPGGPAPGRNAS-- 372
P R + ++S +++ ++ +A+S T G+ P+P +P G R+ S
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP-KPRGLQRSRSRSRR 1779
Query: 373 -----ARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYR-----------SGRHAR 416
RRR S SS S++ R SRS SR + R R G GY+ S R R
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
Query: 417 SRSRS----------------WSRSRSRSRRYSRSRSRGRRHSGGGSRDGHR---YSRSP 457
RSR+ W RSRSR+ + RSR R R R SR
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 458 ARRGGYGPRRRSRSRSHSGDRYRRGGRG---LRHHSSSRSRSSWSLSPSRSRSLTRSRSH 514
+R RRRSRSR+ R R R R S SR+ ++ S SR+ +TR RS
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR 1959
Query: 515 SPSPSQSRSRSRSRSQS---------PSP----------SPAREKLTRPAASPAVGEKLK 555
S +P +R RSRSR+ SP SP + +R SP + +
Sbjct: 1960 SRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2019
Query: 556 KTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDEL 615
P A + ++ L P+++ + R A+ R+ ++ R R
Sbjct: 2020 SRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRS---------------RTPR---- 2060
Query: 616 RAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSR 660
AR R R R S +SRS +P +R +S SR
Sbjct: 2061 --TARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR 2103
Score = 101 bits (251), Expect = 3e-21
Identities = 122/438 (27%), Positives = 184/438 (42%), Gaps = 48/438 (10%)
Query: 250 KHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSS 309
+ ++ ++ +S R+ ++R R R RGR S R S + P +R S S +
Sbjct: 530 RRGRSRSPQRPGWSRSRNTQRRGRSRSAR-RGRSHSRSPATRGRSRSRTPARRGRSRSRT 588
Query: 310 ESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGR 369
+R RSRS TP R + + A G + + PA + +P R
Sbjct: 589 PARRRSRSRTPTRRR----------------SRSRTPARRGRSRSRTPARRRSRTRSPVR 632
Query: 370 NASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRS 429
S R RS + S S SRT + R SRS + +RRG R+ RSRS + +R R
Sbjct: 633 RRS-RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR-RG 690
Query: 430 RRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGG------ 483
R SR+ RGR S R G +SR+P RRG G +++S + R R
Sbjct: 691 RSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMK 750
Query: 484 ------RGLRHHSSSRSR--SSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPS 535
R R SS RS+ S SL S S S + S +P + RSRS S SQ + S
Sbjct: 751 KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR-RSRSGS-SQPKAKS 808
Query: 536 PAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKL---TPQEKLKLRMQKALNRQFKA 592
+ +R ++SP +K KT + + PK+ TP + + +A +
Sbjct: 809 RTPPRRSRSSSSPPPKQK-SKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP 867
Query: 593 DKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRY 652
+++ E E + + + + R+K RQ +S SP P+
Sbjct: 868 QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP--------PRQSPSRSSSPQPKV 919
Query: 653 SREYSSSRRRSRSRSRSP 670
+ S R+RS S S SP
Sbjct: 920 -KAIISPRQRSHSGSSSP 936
Score = 97.8 bits (242), Expect = 3e-20
Identities = 126/464 (27%), Positives = 181/464 (39%), Gaps = 90/464 (19%)
Query: 263 SGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGR 322
SG S ++ L R S S P+ P +RS S+SS +S++++R+P R
Sbjct: 1517 SGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR 1576
Query: 323 -----------EEKITFITSFGGS-----DEEAAAAAAAAAASGVTTGKPPAP------- 359
+ +++ S GS D+ AA A + + K PAP
Sbjct: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636
Query: 360 ----------PQPGGPA--------PGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSR 401
P P G + P ++ +ARR S SS + SRT R SSRSS
Sbjct: 1637 RSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE 1696
Query: 402 SRRGGGYYRSGRHARSRSRSWSRSRSRSRRY-----------SRSRSRGRRHSGGGSRDG 450
R R R A S + SR+ R RR SRS R R S ++
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756
Query: 451 HRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTR 510
R RSP+ + R RSRSR RR R RS S S SR R +R
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRR-----------RDRSGSSQSTSRRRQRSR 1805
Query: 511 SRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKP 570
SRS + R R S S SPAR++ +R ++ G + P ++ ++
Sbjct: 1806 SRS------RVTRRRRGGSGYHSRSPARQESSRTSSRRRRG---RSRTPPTSRKRSRSRT 1856
Query: 571 KLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERR 630
P ++ + R A +R+ ++ + +I + R R RR
Sbjct: 1857 SPAPWKRSRSRASPATHRRSRS-----RTPLISRRRSRSRTSPVSR------------RR 1899
Query: 631 EKEREEWERQYSRQSRSP-SPRYSREYSSSRRRSRSRSRSPHYR 673
+ R R+ SR SP S R SR + R RSRSR+P R
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTR 1943
Score = 89.0 bits (219), Expect = 1e-17
Identities = 139/515 (26%), Positives = 198/515 (38%), Gaps = 100/515 (19%)
Query: 240 RKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDP 299
R+ K+ ++ KH E +K + + +R+ +KR R R +P +RR +
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266
Query: 300 YKRSPSESS-SESRS------------RSRSPTPGRE--------EKITFITSFGGSDE- 337
S S++S S SRS RS SP GR E T T S E
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET 326
Query: 338 -----------------EAAAAAAAAAASGVTTGKPPAPPQP-------GGPAPGRNASA 373
E +A + + +TG P P P G P P
Sbjct: 327 ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL 386
Query: 374 RRRSSSSSSSSSASRTSSSRSS------SRSSSRSRRGGGYYRSGRHARSRSRSWSRSRS 427
+ + S +S +R S S S SS S + RHA S S + +
Sbjct: 387 SQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA 446
Query: 428 R-SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGG------YGPRRRSRSRS-----HS 475
S R S + S G ++ +S +P+RR G R RSRSR+ HS
Sbjct: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506
Query: 476 GDR---------YRRGGRGLRHHSSSRSRS----SWSLSPS-----RSRSLTRSRSHSPS 517
R +R GR RSRS WS S + RSRS R RSHS S
Sbjct: 507 RSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRS 566
Query: 518 PSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEK 577
P+ +R RSRSR +PAR +R + +PA +T T TP +
Sbjct: 567 PA-TRGRSRSR------TPARRGRSR-SRTPARRRSRSRT------PTRRRSRSRTPARR 612
Query: 578 LKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKER--ERREKERE 635
+ R + R+ + + + + + R+ R AR+ R + R RR + R
Sbjct: 613 GRSRSRTPARRRSRT-RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS 671
Query: 636 EWERQYSRQSRSPSP-RYSREYSSSRRRSRSRSRS 669
+ S +SRS +P R R S + RR RSRSRS
Sbjct: 672 RTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRS 706
Score = 80.9 bits (198), Expect = 4e-15
Identities = 95/315 (30%), Positives = 141/315 (44%), Gaps = 39/315 (12%)
Query: 262 YSGRRSRRQRREFREKRLRGRKISPPSYARRD----SPTYDPYKRSPSESSSESRSRSRS 317
+S +R++ +R RGR +PP+ +R SP P+KRS S +S + RSRS
Sbjct: 1821 HSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPA--PWKRSRSRASPATHRRSRS 1878
Query: 318 PTP--------GREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGR 369
TP R ++ S + + + A+ + PP + R
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
Query: 370 NASARRRSSSSSSSSSASRTSSS-------RSSSRSSSRSRRGGGYYRSG---RHARSRS 419
+ RRRS S + + R+ S RS SR+S +RR S R +RSR+
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 420 RSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRY 479
+R RSRSR +R R R + R R SR+P PR+RSRSRS R
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSR-SRTPLL-----PRKRSRSRSPLAIRR 2052
Query: 480 RRGGRGLRHHSSSRSRSSWSLSPS--RSRSLTRS---RSHSPSPSQSRSRSRSRSQSPSP 534
R R R ++R + S + SP R RS + S RS S +P +R+ S SR+ +
Sbjct: 2053 RSRSRTPR---TARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2109
Query: 535 SPAREK-LTRPAASP 548
+ +R +RP+ SP
Sbjct: 2110 NSSRMSCFSRPSMSP 2124
Score = 78.2 bits (191), Expect = 2e-14
Identities = 138/595 (23%), Positives = 213/595 (35%), Gaps = 95/595 (15%)
Query: 152 EKKKLAEKKASIGYTYEDSTV---AEVEKAAEKPEEEESAAEEESNSDEDEVIPDI---- 204
E++++ EK A+ + V + E ++P E+ E N ++E +
Sbjct: 83 EEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGIS 142
Query: 205 DVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSG 264
D VD + ++ A KQ VR + K K ++++ S
Sbjct: 143 DSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKK-KKDRGRRSE 201
Query: 265 RRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREE 324
S R+ R+ K+ + R S + SPT ++S + SRS + +P R
Sbjct: 202 SSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH 261
Query: 325 KITFITSFGGSDEEAAAAAAAAAASGVT--TGKPPAP------------PQPGGPAPGRN 370
+ T S SD + + +AAA + T G+ P+P +PG + R
Sbjct: 262 RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321
Query: 371 ASARRRSSSSSS--------SSSASRTSSSRSSSRSSS-----------RSRRGGG---- 407
+S + SS S T S S RSS+ R GG
Sbjct: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
Query: 408 ---------YYRSGRHARSRSRSWSRSRSRSRRYSRSRS--------RGRRHSGGGSRD- 449
+ +R RS +S + + S S S + RH+
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
Query: 450 -------GHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP 502
HR S R R +SHS RR GR SRS ++
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGR-------SRSPATAKRGR 494
Query: 503 SRSRSLT-RSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAA 561
SRSR+ T R S S SP RSRS R S SP R +R P G +
Sbjct: 495 SRSRTPTKRGHSRSRSPQWRRSRSAQR-WGRSRSPQRRGRSRSPQRP--GWSRSRNTQRR 551
Query: 562 GKETGAAKPK---LTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAM 618
G+ A + + +P + + R + R + A+ + + R
Sbjct: 552 GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTR---------- 601
Query: 619 ARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
R+ R + RR + R + ++RSP R SR S +RR RSRSR+P R
Sbjct: 602 -RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR 655
Score = 75.5 bits (184), Expect = 2e-13
Identities = 98/357 (27%), Positives = 144/357 (40%), Gaps = 63/357 (17%)
Query: 280 RGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEK-------------- 325
R R +PPS + T + R+PS SS ++ S+S P +++
Sbjct: 2404 RARSRTPPSAPSQSRMTSE---RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 2460
Query: 326 --ITFITSFGGSDEEAAAAAAAAAAS-------------GVT---TGKPPAPP---QPGG 364
I T GS ++ A A +S GV G+PPA QP
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
Query: 365 PAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSR 424
A + A RR SSSSSSSSS+S +SSS SSS SSS S S S S
Sbjct: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS--------------SSSDSEGS 2566
Query: 425 SRSRSRRYSRSRSRGRRHSGGGS-RDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGG 483
S + R + + R+G +PA+R +RRS S S S
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKR-----KRRSSSSSSSSSSSSSSS 2621
Query: 484 RGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTR 543
SSS S SS S S S S S + S S SPSP++ ++ + SP P E+ +R
Sbjct: 2622 S-----SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
Query: 544 PAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEK 600
P + ++ + E P+ +P+++ ++ R + D ++ K
Sbjct: 2677 SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK 2733
Score = 70.5 bits (171), Expect = 5e-12
Identities = 85/257 (33%), Positives = 108/257 (42%), Gaps = 32/257 (12%)
Query: 287 PSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAA 346
P+ RR S + S S SSS S S S S + + + + + + + A
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585
Query: 347 AASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGG 406
V G+PP P PA + RR SSSSSSSSS+S +SSS SSS SSS
Sbjct: 2586 PKEAVREGRPPEPT----PAKRK----RRSSSSSSSSSSSSSSSSSSSSSSSSS------ 2631
Query: 407 GYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPR 466
S + S S S S S S S ++ + S G R SRSP R
Sbjct: 2632 ----SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP--RKPIDSL 2685
Query: 467 RRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSR 526
R SRS S+S RR S R + S S S S R S SPS R
Sbjct: 2686 RDSRSLSYSPVERRRPS----PQPSPRDQQS---SSSERGSRRGQRGDSRSPSHKR---- 2734
Query: 527 SRSQSPSPSPAREKLTR 543
R ++PSP P R + +R
Sbjct: 2735 -RRETPSPRPMRHRSSR 2750
Score = 69.3 bits (168), Expect = 1e-11
Identities = 135/513 (26%), Positives = 185/513 (36%), Gaps = 120/513 (23%)
Query: 268 RRQRREFREKRLRGRKISPPSYARRDSPTYDPYKR-----SPSESSSESRSR-------S 315
RR R +R R R +P ARR S T P +R SP+ S SRSR S
Sbjct: 602 RRSRSRTPARRGRSRSRTP---ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRS 658
Query: 316 RSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPG----GPAPGRNA 371
RS TP R + T S + A S T + G + R
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718
Query: 372 SARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRR 431
R RS SSS + SRTS RS S SS ++ R RSRS S RS+++SR
Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSR-----RSRSLSSPRSKAKSRL 773
Query: 432 YSRSRSRGR------------RHSGGGSRDGHRYSRSPARRGGYG-----------PRRR 468
R G R S GS SR+P RR P R+
Sbjct: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ 833
Query: 469 SRSRSH------SGDRYRRGG-----------------------------RGLRHHSSS- 492
S S S SG R+G R HS S
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG 893
Query: 493 ------RSRSSWSLSPSRSRS---------LTRSRSH----SPSPSQSRSRS---RSRSQ 530
+S + SPSRS S R RSH SPSPS+ SR+ RSRS
Sbjct: 894 SSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV 953
Query: 531 SPSPSPAREKLTR--PAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALN- 587
SP + L R + S + K+K P +G+ P P+ K + +L+
Sbjct: 954 SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP--YPKVKAQTPPGPSLSG 1011
Query: 588 RQFKADKKAAQEKMIQQ---------EHERQEREDELRAMARKIRMKERERREKE-REEW 637
+ ++ +++ ++Q + E +++K + + + R +
Sbjct: 1012 SKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT 1071
Query: 638 ERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
RQS S SP + +S + RSRS SP
Sbjct: 1072 SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSP 1104
Score = 68.6 bits (166), Expect = 2e-11
Identities = 115/521 (22%), Positives = 184/521 (35%), Gaps = 44/521 (8%)
Query: 178 AAEKPEEEESAAEEESNSDEDEVIPDIDV-EVDVDELNQEQVADLNKQATTYGMADGDFV 236
A PE +E + ++S ++E++ ++ E ++ ++L + +T+ + +
Sbjct: 1216 AGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVE 1275
Query: 237 RM----LRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARR 292
L D+ +++A A + + + G + +E LR P R
Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRN 1335
Query: 293 DSPTYDPYKRSPSESSSES------RSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAA 346
P S E P+ +E+ T + S+ A A
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAG 1395
Query: 347 AASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSS--SSSSASRTSSSRSSSRSSSRSRR 404
+S + P P R S R SS+SS RT S RS S SS R
Sbjct: 1396 MSSNQSISSPVLDAVP------RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
Query: 405 GGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPA----RR 460
G G RH+ S S + R+ RS + SRSP+
Sbjct: 1450 GSG--TPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNN 1507
Query: 461 GGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP-------SRSRSLTRSRS 513
P+R S D+ L S S S + P S S S S++
Sbjct: 1508 KCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKA 1567
Query: 514 HSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLT 573
+ +P + RSRS S + S S + +R +SP V +K + A + +PK
Sbjct: 1568 KTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAP 1627
Query: 574 PQEKLKLRMQKALNRQFKA-DKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREK 632
L R + + + + + + EH + R AR+ E + K
Sbjct: 1628 APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR------TARRGSRSSPEPKTK 1681
Query: 633 EREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
R R+ SR SP +R+ S RRSRS S SP R
Sbjct: 1682 SRTPPRRRSSRS----SPELTRKARLS-RRSRSASSSPETR 1717
Score = 67.4 bits (163), Expect = 4e-11
Identities = 100/423 (23%), Positives = 152/423 (35%), Gaps = 63/423 (14%)
Query: 280 RGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPT--------PGREEKITFITS 331
R R S S +D P +RS S SS R S +P+ PG ++ I S
Sbjct: 1416 RERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD-IPRTPS 1474
Query: 332 FGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSS 391
G S+ +++ A + + P+ P+ + +R S S SS +
Sbjct: 1475 RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKC----LTPQRERSGSESSVDQKTVAR 1530
Query: 392 SRSSSRSSSRSRRGGGYYRSGR-HARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDG 450
+ RS S S + S RS S S S++++R R RSR G S +
Sbjct: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS-----GSSPEV 1585
Query: 451 HRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTR 510
SR RR G + + + R + G + R+ P RSRS +
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL----PRRSRSGSS 1641
Query: 511 SRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKP 570
S+ PSP S S S P AR S + E K+ + + + P
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARR------GSRSSPEPKTKSRTPPRRRSSRSSP 1695
Query: 571 KLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERR 630
+LT + +L R + A ++ + + R R + + + + RR
Sbjct: 1696 ELTRKARLSRRSRSA----------SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR 1745
Query: 631 EKEREEWERQYSRQSRSPSP------------------------RYSREYSSSRRRSRSR 666
+ SR+ RSPSP R S+SRRR RSR
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805
Query: 667 SRS 669
SRS
Sbjct: 1806 SRS 1808
Score = 56.2 bits (134), Expect = 9e-08
Identities = 108/362 (29%), Positives = 136/362 (37%), Gaps = 83/362 (22%)
Query: 265 RRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREE 324
RRSR + +R R R SP S R S T +RS S +S SR RSRS TP
Sbjct: 1874 RRSRSRTPLISRRRSRSRT-SPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP---- 1928
Query: 325 KITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSS 384
+T S + + + + PP + R + RR S S +S
Sbjct: 1929 PVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSP 1988
Query: 385 SASRTSSSRSS--SRSSSRSRRGGGYYRSGR-------HARSRSRS----WSRSRSRS-- 429
R S SR+S +R SRSR R R RSRSR+ RSRSRS
Sbjct: 1989 VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPL 2048
Query: 430 --RRYSRSRS----RG------------RRHSGGGSRDGHRYSRSPARRGGYGPR----- 466
RR SRSR+ RG RR + G S D R + PA R G R
Sbjct: 2049 AIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVA 2108
Query: 467 -RRSRSRSHSG--------DRYRRGGRGLRHHSSSRS----------------------- 494
SR S DR R G L SSR+
Sbjct: 2109 LNSSRMSCFSRPSMSPTPLDRCRSPGM-LEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDH 2167
Query: 495 -RSSWSLSPSRSRSLTRSRSHS-----PSPSQSRSRSRSR-SQSPSPSPAREKLTRPAAS 547
R+S + ++SR + S P PS S + +R SQ P+P P T PAA+
Sbjct: 2168 QRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAAN 2227
Query: 548 PA 549
A
Sbjct: 2228 LA 2229
Score = 49.7 bits (117), Expect = 9e-06
Identities = 51/161 (31%), Positives = 72/161 (44%), Gaps = 17/161 (10%)
Query: 301 KRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPP 360
+RS S SSS S S S S +S S ++++++++++S ++ P+P
Sbjct: 2605 RRSSSSSSSSSSSSSSS------------SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 361 QPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRS---RRGGGYYRSGRHARS 417
+PG A + AS ++ S S + S SRS S S RR S R +S
Sbjct: 2653 KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQS 2712
Query: 418 RSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRD-GHRYSRSP 457
S S SR R SRS S RR R HR SRSP
Sbjct: 2713 -SSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 110 bits (276), Expect = 3e-24
Identities = 122/441 (27%), Positives = 181/441 (41%), Gaps = 35/441 (7%)
Query: 245 EAEAIKHAKALEEEKAMYSGRRSRRQRREFREK-----RLRGRKISPPSYARRDSPTYDP 299
E ++HA+ + + SGR RR R+K R R I +R
Sbjct: 63 ERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKD 122
Query: 300 YKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAP 359
Y R E + + R E I F+ S + A + V K
Sbjct: 123 YMRQAGEVTYADAHKGRK----NEGVIEFV-----SYSDMKRALEKLDGTEVNGRKIRLV 173
Query: 360 PQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRS 419
G R+ S R S S S S SR S SRS S SS S+ RSG +RS+S
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK-SRSRSRSGSRSRSKS 232
Query: 420 RSWSRSRSRSRRY-----SRSRSRGRRHSGGGSRDGHR-YSRSPARRGGYGPRRRSRSRS 473
RS S+SRSRS++ S+ +SR R HS G SR + + + + +SRS S
Sbjct: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292
Query: 474 HSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPS 533
+ + R R S S S+ +SL +SRS S S SRSRSRSRS+S
Sbjct: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
Query: 534 PSP----AREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQ 589
+RE+ + S + E+ +K + G++K K +E ++ +R
Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK--KKEDTDRSQSRSPSRS 410
Query: 590 FKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPS 649
+++ A+ + Q+E + +E R + + + +SRS S
Sbjct: 411 VSKEREHAKSESSQREGRGESENAGTN--------QETRSRSRSNSKSKPNLPSESRSRS 462
Query: 650 PRYSREYSSSRRRSRSRSRSP 670
S+ S S+ RSRS SRSP
Sbjct: 463 KSASKTRSRSKSRSRSASRSP 483
Score = 108 bits (270), Expect = 2e-23
Identities = 110/308 (35%), Positives = 138/308 (44%), Gaps = 44/308 (14%)
Query: 263 SGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSR---SPT 319
S RSR + R R+ R R R RS S S S+SRSRS+ S +
Sbjct: 190 SHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRS 249
Query: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPA--PPQPGGPAPGRNASARRRS 377
P +E+ + S G S ++ A + GKP + P + + R+ S RR
Sbjct: 250 PSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRV 309
Query: 378 --------SSSSSSSSASRTSSSRSSSRSSSRSR-RGGGYYRSGRHARSRSRSWSRSRSR 428
S S + R S SRS S+ SRSR R + R R RSR SRSRSR
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR 369
Query: 429 SRRYS-RSRSRG-RRHSGGGSRDGHR-------YSRSPARRGGYGPRRRSRSRSHSGDRY 479
SR S RSR RG +R S GS + SRSP+R + R ++S S R
Sbjct: 370 SRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS---KEREHAKSESSQRE 426
Query: 480 RRG---GRGLRHHSSSRSRS---------------SWSLSPSRSRSLTRSRSHSPSPSQS 521
RG G + SRSRS S S S +RSRS +RSRS S SPS+S
Sbjct: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486
Query: 522 RSRSRSRS 529
RSRS SRS
Sbjct: 487 RSRSHSRS 494
Score = 100 bits (249), Expect = 4e-21
Identities = 119/391 (30%), Positives = 166/391 (42%), Gaps = 65/391 (16%)
Query: 179 AEKPEEEESAAEEESNSDEDEVIPDID-VEVDVDELNQEQVADLNKQATTYGMADGDF-- 235
A K + E E S SD + +D EV+ ++ + +++ +Y +
Sbjct: 135 AHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRS 194
Query: 236 ---VRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARR 292
R RK + + + K + + ++ SG RSR + R + R R +K
Sbjct: 195 RSRSRHSRKSRSRSGSSKSSHSKSRSRSR-SGSRSRSKSRSRSQSRSRSKKEK------- 246
Query: 293 DSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVT 352
RSPS+ S SRS S G S ++ A +
Sbjct: 247 --------SRSPSKEKSRSRSHSA----------------GKSRSKSKDQAEEKIQNNDN 282
Query: 353 TGKPP--APPQPGGPAPGRNASARRR--------SSSSSSSSSASRTSSSRSSSRSSSRS 402
GKP +P + + R+ S RR S S + R S SRS S+ SRS
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 403 R-RGGGYYRSGRHARSRSRSWSRSRSRSRRYS-RSRSRG-RRHSGGGSRDGHR------- 452
R R + R R RSR SRSRSRSR S RSR RG +R S GS +
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 453 YSRSPARRGGYGPRRRSRSRSHSGDRYRRG---GRGLRHHSSSRSRSSWSLSPSRSRSLT 509
SRSP+R + R ++S S R RG G + SRSRS+ S S S +
Sbjct: 403 QSRSPSRSVS---KEREHAKSESSQREGRGESENAGTNQETRSRSRSN-SKSKPNLPSES 458
Query: 510 RSRSHSPSPSQSRSRSRSRSQSPSPSPAREK 540
RSRS S S ++SRS+SRSRS S SPS +R +
Sbjct: 459 RSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 80.9 bits (198), Expect = 4e-15
Identities = 75/214 (35%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 464 GPRRR---SRSRSHSGDRYR-RGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPS 519
G RRR SRSRSHS R R R R R S S S+SS S S SRSRS +RSRS S S S
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 520 QSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLK 579
QSRSRS+ + +S SPS + + +A + + + E KPK + K
Sbjct: 237 QSRSRSK-KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK 295
Query: 580 LRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWER 639
K+ +R +++ +EK R + + R+ R + R + R
Sbjct: 296 ---SKSKSRSRSQERRVEEEKRGSVSRGRSQEKS-----LRQSRSRSRSKGGSRSRSRSR 347
Query: 640 QYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
S+ R R SRE S SR RSRS+S R
Sbjct: 348 SKSKDKRKGRKR-SREESRSRSRSRSKSERSRKR 380
Score = 75.1 bits (183), Expect = 2e-13
Identities = 82/304 (26%), Positives = 126/304 (41%), Gaps = 25/304 (8%)
Query: 393 RSSSRSSSRSRRGGGYYRSGRH-----ARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS 447
R S S RS G GY RSGR R+ R + S + + R+
Sbjct: 75 RDGSYGSGRS--GYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTY 132
Query: 448 RDGH--RYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRS 505
D H R + Y +R+ + + R R + SR R S+S S S S
Sbjct: 133 ADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHS 192
Query: 506 RSLTRSR--------------SHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVG 551
RS +RSR SHS S S+SRS SRSRS+S S S +R + + +
Sbjct: 193 RSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK 252
Query: 552 EKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEH--ERQ 609
EK + +AGK +K + + + + K +R K ++ + QE E +
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE 312
Query: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
+R R +++ +++ R + + + +S+S R R+ S RSRSRSRS
Sbjct: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS 372
Query: 670 PHYR 673
R
Sbjct: 373 KSER 376
Score = 46.2 bits (108), Expect = 1e-04
Identities = 72/293 (24%), Positives = 114/293 (38%), Gaps = 77/293 (26%)
Query: 446 GSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSR-----------S 494
G R ++R P R G YG R SG YRR GR ++ +R S
Sbjct: 62 GERVIVEHARGPRRDGSYGSGR-------SGYGYRRSGRD-KYGPPTRTEYRLIVENLSS 113
Query: 495 RSSWSLSPSRSR---SLTRSRSH------------------------------------- 514
R SW R +T + +H
Sbjct: 114 RCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLV 173
Query: 515 SPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGA-AKPKLT 573
P R RS SRS+S S S +R + +R + S + K ++ + +G+ ++ K
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 574 PQEKLKLRMQKALNRQFKADKK--------AAQEKMIQQEHERQEREDEL-----RAMAR 620
+ + + R +K +R +K ++ K Q E+ + D + R+ +R
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 621 -KIRMKERERREKEREEWERQYS---RQSRSPSPRYSREYSSSRRRSRSRSRS 669
K + K R R ++ R E E++ S +S+ S R SR S S+ SRSRSRS
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Score = 30.4 bits (67), Expect = 5.6
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
E+ D RKIR+ E + + R + SRS S SR S R+SRSRS S
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSY-------SRSRSHSRSRSRSRHSRKSRSRSGS 210
Query: 670 PHYRH 674
H
Sbjct: 211 SKSSH 215
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 95.5 bits (236), Expect = 1e-19
Identities = 84/268 (31%), Positives = 116/268 (43%), Gaps = 33/268 (12%)
Query: 368 GRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRS-R 426
GR +S S S R SSS SSS S + SR+ GG R +RS+SRSWSR +
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGG-----RKSRSKSRSWSRDLQ 56
Query: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRR-SRSRSHSGDRYRRGGRG 485
RS Y R R R S S G R RS +R G G R RSRS S R R
Sbjct: 57 PRSHSYDRRR---RHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPR 113
Query: 486 LRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPA 545
LR HS S RSS + SRSR R + + R + + + +
Sbjct: 114 LRSHSRSSERSSHRRTRSRSRDRERRKGRD---KEKREKEKDKGKD-------------- 156
Query: 546 ASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQE 605
++L + A L P E+ K R+Q L KAD+ ++ ++E
Sbjct: 157 ------KELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERNEEE 210
Query: 606 HERQEREDELRAMARKIRMKERERREKE 633
+R++ ED+ + + R+KE E E +
Sbjct: 211 AKRRKEEDQATLVEQVKRVKEIEAIESD 238
Score = 59.3 bits (142), Expect = 1e-08
Identities = 70/261 (26%), Positives = 93/261 (35%), Gaps = 76/261 (29%)
Query: 264 GRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGRE 323
GRRS E R KR + + S + DS TY K+ +S S+SRS SR P
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSR-KKGGRKSRSKSRSWSRDLQPR-- 58
Query: 324 EKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSS 383
+ RRR SSSSS
Sbjct: 59 --------------------------------------------SHSYDRRRRHRSSSSS 74
Query: 384 SSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHS 443
S SR SRS SR +S R RS S+SR+R SRSR R R HS
Sbjct: 75 SYGSRRKRSRSRSRGRGKSYRV-------------QRSRSKSRTRR---SRSRPRLRSHS 118
Query: 444 GGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPS 503
R HR +RS R R R R D+ +R + + + ++
Sbjct: 119 RSSERSSHRRTRS---------RSRDRERRKGRDKEKRE----KEKDKGKDKELHNIKRG 165
Query: 504 RSRSLTRSRSHSPSPSQSRSR 524
S ++ H P Q+++R
Sbjct: 166 ESGNIKAGLEHLPPAEQAKAR 186
Score = 46.6 bits (109), Expect = 8e-05
Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 17/166 (10%)
Query: 472 RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQS 531
RS + R R +H S S SS S S T SR S+S+SRS SR
Sbjct: 4 RSSDTEEESRSKRKKKHRRRSSSSSS-------SDSRTYSRKKGGRKSRSKSRSWSRDLQ 56
Query: 532 P-SPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQF 590
P S S R + R ++S + G + K++ + G K + + K R +++ +R
Sbjct: 57 PRSHSYDRRRRHRSSSSSSYGSRRKRSR---SRSRGRGKSYRVQRSRSKSRTRRSRSRPR 113
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREE 636
+ E+ + + R+ E R + +++E+REKE+++
Sbjct: 114 LRSHSRSSERSSHRRTRSRSRDRERR------KGRDKEKREKEKDK 153
Score = 35.4 bits (80), Expect = 0.17
Identities = 20/52 (38%), Positives = 28/52 (53%)
Query: 618 MARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
M R+ E E R K +++ R+ S S S S YSR+ + RS+SRS S
Sbjct: 1 MGRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWS 52
Score = 35.4 bits (80), Expect = 0.17
Identities = 55/218 (25%), Positives = 73/218 (33%), Gaps = 64/218 (29%)
Query: 242 DKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYK 301
D EE K K + S SR R+ ++ R + S + S +YD +
Sbjct: 7 DTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRR 66
Query: 302 RSPSESSS---ESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPA 358
R S SSS R RSRS + GR
Sbjct: 67 RHRSSSSSSYGSRRKRSRSRSRGR------------------------------------ 90
Query: 359 PPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSR 418
G++ +R S S + S SR RS SRSS RS S
Sbjct: 91 ---------GKSYRVQRSRSKSRTRRSRSR-PRLRSHSRSSERS--------------SH 126
Query: 419 SRSWSRSRSRSRRYSRSR-SRGRRHSGGGSRDGHRYSR 455
R+ SRSR R RR R + R + G ++ H R
Sbjct: 127 RRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKR 164
Score = 34.7 bits (78), Expect = 0.30
Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 5/98 (5%)
Query: 581 RMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQ 640
R ++ +R + D + ++ R + ++ R + R R + R + R
Sbjct: 42 RKSRSKSRSWSRDLQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRS 101
Query: 641 YSRQSRSPSPRYSREYS-----SSRRRSRSRSRSPHYR 673
SR RS S R +S SS RR+RSRSR R
Sbjct: 102 KSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERR 139
Score = 30.0 bits (66), Expect = 7.3
Identities = 21/83 (25%), Positives = 31/83 (37%), Gaps = 6/83 (7%)
Query: 592 ADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPR 651
+D + +++H R+ R K + + W R +S S R
Sbjct: 6 SDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRR 65
Query: 652 ------YSREYSSSRRRSRSRSR 668
S Y S R+RSRSRSR
Sbjct: 66 RRHRSSSSSSYGSRRKRSRSRSR 88
Score = 29.6 bits (65), Expect = 9.5
Identities = 23/106 (21%), Positives = 48/106 (45%), Gaps = 7/106 (6%)
Query: 573 TPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKER--ERR 630
T +E R +K +R+ + ++ + ++ ++ + R+ +R ++ + +RR
Sbjct: 8 TEEESRSKRKKK--HRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRR 65
Query: 631 EKEREEWERQYS---RQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
+ R Y ++SRS S + Y R RS+SR+R R
Sbjct: 66 RRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSR 111
>gi|46309849 hypothetical protein LOC57035 [Homo sapiens]
Length = 290
Score = 92.4 bits (228), Expect = 1e-18
Identities = 83/223 (37%), Positives = 108/223 (48%), Gaps = 11/223 (4%)
Query: 356 PPAPPQPGGPAPGRNASARRRSSSSSSSS-SASRTSSSRSSSRSSSRSRRGGGYYRSGRH 414
P +P + P+ R+ + R SS S S S S S S SR SSR SSRSRR RS R
Sbjct: 10 PGSPQEKDSPSTSRSGGSSRLSSRSRSRSFSRSSRSHSRVSSRFSSRSRRSKSRSRSRRR 69
Query: 415 ARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR-RGGYGPRRRSRSRS 473
+ + R +SRS SRSR SRSR R R G +R RY RSP+R R R RSR RS
Sbjct: 70 HQRKYRRYSRSYSRSRSRSRSR-RYRERRYGFTR---RYYRSPSRYRSRSRSRSRSRGRS 125
Query: 474 HSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRS---RSRSQ 530
+ G Y RG R++ R+ S R RS TRSRS +P + R
Sbjct: 126 YCGRAYAI-ARGQRYYGFGRTVYPEEHSRWRDRSRTRSRSRTPFRLSEKDRMELLEIAKT 184
Query: 531 SPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLT 573
+ + + + PA+ V K+T G + AKP+L+
Sbjct: 185 NAAKALGTTNIDLPASLRTV-PSAKETSRGIGVSSNGAKPELS 226
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 12/78 (15%)
Query: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSR-QSRSPSPRY-SREYSSSRR 661
+ H R R+ K R + R R +++ + R YSR +SRS S RY R Y +RR
Sbjct: 44 RSHSRVSSRFSSRSRRSKSRSRSRRRHQRKYRRYSRSYSRSRSRSRSRRYRERRYGFTRR 103
Query: 662 ----------RSRSRSRS 669
RSRSRSRS
Sbjct: 104 YYRSPSRYRSRSRSRSRS 121
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/51 (49%), Positives = 28/51 (54%), Gaps = 8/51 (15%)
Query: 623 RMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
R R RR K R R++ R+ R RYSR YS RSRSRSRS YR
Sbjct: 52 RFSSRSRRSKSRSRSRRRHQRKYR----RYSRSYS----RSRSRSRSRRYR 94
Score = 37.4 bits (85), Expect = 0.046
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 16/97 (16%)
Query: 222 NKQATTYGMADGDFVRMLRKDKEEAEAIK-HAKALEEEKAMYSGRRSRRQRREFREKRLR 280
++ + ++ F R+ K + + + H + YS RSR + R +RE+R
Sbjct: 40 SRSSRSHSRVSSRFSSRSRRSKSRSRSRRRHQRKYRRYSRSYSRSRSRSRSRRYRERRY- 98
Query: 281 GRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRS 317
+ RR Y RSPS S SRSRSRS
Sbjct: 99 -------GFTRR-------YYRSPSRYRSRSRSRSRS 121
Score = 33.5 bits (75), Expect = 0.66
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 12/123 (9%)
Query: 551 GEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNR---QFKA-DKKAAQEKMIQQEH 606
G +K P+ + G+++ + + R ++ +R +F + +++ ++ H
Sbjct: 11 GSPQEKDSPSTSRSGGSSRLSSRSRSRSFSRSSRSHSRVSSRFSSRSRRSKSRSRSRRRH 70
Query: 607 ERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSR 666
+R+ R + R + R RE+ R Y RSP SR S SR RSRSR
Sbjct: 71 QRKYRRYSRSYSRSRSRSRSRRYRERRYGFTRRYY----RSP----SRYRSRSRSRSRSR 122
Query: 667 SRS 669
RS
Sbjct: 123 GRS 125
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 91.3 bits (225), Expect = 3e-18
Identities = 73/175 (41%), Positives = 83/175 (47%), Gaps = 13/175 (7%)
Query: 387 SRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGG 446
SR R SR RR Y R R R R RS SR S SR SRSR RG R+S
Sbjct: 100 SRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSP 159
Query: 447 -SRDGH---RYSRSPARRGGYGPRR----RSRSRSHSGDRYRRGGRGLRHHSSSRSRSSW 498
SR + RYSRSP R Y R S +S RY R H S S SS
Sbjct: 160 YSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSR 219
Query: 499 SLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSP-----SPSPAREKLTRPAASP 548
S S S+S S RS+S S S S+SRSRS S ++SP S +R + RP SP
Sbjct: 220 SASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSP 274
Score = 82.0 bits (201), Expect = 2e-15
Identities = 74/192 (38%), Positives = 88/192 (45%), Gaps = 13/192 (6%)
Query: 354 GKPPAPPQPGGPAPGRNASA---RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYR 410
G+ P G GR+ RR S S S R SRS S SRSR YR
Sbjct: 93 GRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSR-SRSRYR 151
Query: 411 SGRHARSR-SRS-WSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRR 468
R++RS SRS +SRSR YSRSR R R+ G YS S Y
Sbjct: 152 GSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGS------HYSSSGYSNSRYSRYHS 205
Query: 469 SRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHS-PSPSQSRSRSRS 527
SRS S SG SS+R S S+S SRSRS + S + S P S+ +S+SRS
Sbjct: 206 SRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRS 265
Query: 528 RSQSPSPSPARE 539
RS+ P SP E
Sbjct: 266 RSKRPPKSPEEE 277
Score = 55.5 bits (132), Expect = 2e-07
Identities = 69/226 (30%), Positives = 92/226 (40%), Gaps = 16/226 (7%)
Query: 240 RKDKEEAEAIKHAKALE-EEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYD 298
R+D ++AEA L+ E + R RR R+ RGR Y RR S +Y
Sbjct: 65 RRDAQDAEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGG-GYGRR-SRSYG 122
Query: 299 PYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPA 358
RSP RSRSR P+ R + + GS + + + S + +
Sbjct: 123 RRSRSPRR---RHRSRSRGPSCSRSRSRS---RYRGS----RYSRSPYSRSPYSRSRYSR 172
Query: 359 PPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRS-SSRSRRGGGYYRSG--RHA 415
P SSS S+S SR SSRS S+S SS S R +S R +
Sbjct: 173 SPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRS 232
Query: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRG 461
+S S S SRSRSRS +RS R + R +SP G
Sbjct: 233 KSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEG 278
Score = 53.9 bits (128), Expect = 5e-07
Identities = 86/315 (27%), Positives = 118/315 (37%), Gaps = 63/315 (20%)
Query: 147 RPSEDEKKKLAEKKASIGYTY---EDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIPD 203
R S D +++ EK +G Y E T A A + + A + E+ D E+
Sbjct: 24 RTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDGAEL--- 80
Query: 204 IDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYS 263
+L Q YG D + R + E Y
Sbjct: 81 -------------DGRELRVQVARYGRRD-----LPRSRQGEPRGRSRGGGYGRRSRSY- 121
Query: 264 GRRSRRQRREFREKRLRGRKISPPSYARRDSPTY--DPYKRSPSESSSESRSR-SRSPTP 320
GRRSR RR R R R P R Y Y RSP S SRSR SRSP
Sbjct: 122 GRRSRSPRR-----RHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYS 176
Query: 321 GREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSS 380
+ + +GGS ++SG + + + ++ S+ S+S
Sbjct: 177 RSRYRES---RYGGSHY---------SSSGYSNSRYSR--YHSSRSHSKSGSSTSSRSAS 222
Query: 381 SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR-SRRYSRSRSRG 439
+S SS++R S S S SRS S RSRS S +RS R S+R S+SRSR
Sbjct: 223 TSKSSSARRSKSSSVSRSRS---------------RSRSSSMTRSPPRVSKRKSKSRSRS 267
Query: 440 RRHSGGGSRDGHRYS 454
+R +G S
Sbjct: 268 KRPPKSPEEEGQMSS 282
Score = 44.7 bits (104), Expect = 3e-04
Identities = 59/229 (25%), Positives = 77/229 (33%), Gaps = 38/229 (16%)
Query: 445 GGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGD---RYRRGGRGLRHHSSSRSRSSWSLS 501
G DG AR G RR RS G+ R R GG G R SRS S S
Sbjct: 77 GAELDGRELRVQVARYG-----RRDLPRSRQGEPRGRSRGGGYGRR----SRSYGRRSRS 127
Query: 502 PSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAA 561
P R RSRS PS S+SRSRSR R S SP + SP + ++
Sbjct: 128 PRRRH---RSRSRGPSCSRSRSRSRYRGSRYSRSPY-------SRSPYSRSRYSRS---- 173
Query: 562 GKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARK 621
P + + R + + + + + +
Sbjct: 174 ------------PYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSA 221
Query: 622 IRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
K R + R SR S R S + +SRSRS+ P
Sbjct: 222 STSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRP 270
Score = 30.8 bits (68), Expect = 4.3
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 609 QEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
+ R+ E R +R R R R R+ R SRS P SR S SR R SR
Sbjct: 99 RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHR-SRSRGPSCSRSRSRSRYRGSRYSR 157
Query: 669 SPHYR 673
SP+ R
Sbjct: 158 SPYSR 162
Score = 30.0 bits (66), Expect = 7.3
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 616 RAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSR-SRSPHYR 673
R+ R+ R R R + R + +SR RYSR S SRSR SRSP+ R
Sbjct: 119 RSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSR 177
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 90.9 bits (224), Expect = 3e-18
Identities = 76/170 (44%), Positives = 97/170 (57%), Gaps = 18/170 (10%)
Query: 372 SARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSR- 430
++ RRS S S S S SR S RS SR SSRSR S +RSRSRS RSRSRS+
Sbjct: 185 TSHRRSYSGSRSRSRSRRRS-RSRSRRSSRSRSRS---ISKSRSRSRSRSKGRSRSRSKG 240
Query: 431 RYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRG----- 485
R SRS+S+ + S GS H +SRS ++ R RSRSRS + G+G
Sbjct: 241 RKSRSKSKSKPKSDRGS---HSHSRSRSKDEYEKSRSRSRSRSP-----KENGKGDIKSK 292
Query: 486 LRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPS 535
R S SRS S + PS++RS++ + S S+SRSRS+SRS+S S S
Sbjct: 293 SRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
Score = 85.5 bits (210), Expect = 1e-16
Identities = 73/162 (45%), Positives = 86/162 (53%), Gaps = 28/162 (17%)
Query: 388 RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS 447
RTS RS S S SRSR S R +RSRSR SRSRSRS S+SRSR R S G S
Sbjct: 184 RTSHRRSYSGSRSRSR-------SRRRSRSRSRRSSRSRSRS--ISKSRSRSRSRSKGRS 234
Query: 448 RDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRS 507
R SRS R+SRS+S S + RG HS SRSRS SRSRS
Sbjct: 235 R-----SRSKG--------RKSRSKSKSKPKSDRGS-----HSHSRSRSKDEYEKSRSRS 276
Query: 508 LTRS-RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP 548
+RS + + +S+SRSRS+S+S SP P R + P
Sbjct: 277 RSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPP 318
Score = 70.9 bits (172), Expect = 4e-12
Identities = 72/182 (39%), Positives = 86/182 (47%), Gaps = 23/182 (12%)
Query: 374 RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRG----GGYYRSGRHARSRSRSWSRSRSRS 429
R+ + + + RT+ RS S +R G +GR+ R S RS
Sbjct: 131 RQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRS 190
Query: 430 RRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHH 489
SRSRSR RR S SR R SRS +R R RSRSRS R R GR R
Sbjct: 191 YSGSRSRSRSRRRSRSRSR---RSSRSRSRSISKS-RSRSRSRSKGRSRSRSKGRKSRSK 246
Query: 490 SSSRSRSS-WSLSPSRSRS-----LTRSRSHSPSP---------SQSRSRSRSRSQSPSP 534
S S+ +S S S SRSRS +RSRS S SP S+SRSRS+SRS SP P
Sbjct: 247 SKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLP 306
Query: 535 SP 536
P
Sbjct: 307 VP 308
Score = 60.1 bits (144), Expect = 7e-09
Identities = 69/230 (30%), Positives = 87/230 (37%), Gaps = 78/230 (33%)
Query: 300 YKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAP 359
Y S S S S RSRSRS R + S
Sbjct: 191 YSGSRSRSRSRRRSRSRSRRSSRSRSRSISKS---------------------------- 222
Query: 360 PQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRS 419
+R RS S S S S+ SRS S+S +S RG S H+RSRS
Sbjct: 223 ------------RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRG-----SHSHSRSRS 265
Query: 420 R-SWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDR 478
+ + +SR SRSRSR + +G G SRS +R P S++R
Sbjct: 266 KDEYEKSR------SRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKAR------ 313
Query: 479 YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSR 528
S+SP R+ +RSRS S S S+SRSRS SR
Sbjct: 314 --------------------SVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Score = 57.0 bits (136), Expect = 6e-08
Identities = 54/184 (29%), Positives = 76/184 (41%), Gaps = 33/184 (17%)
Query: 487 RHHSSSRSRS-SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPA 545
R +S SRSRS S S SRSR +RSRS S S S+SRSRSRS+ +S S S R+ ++
Sbjct: 189 RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSK 248
Query: 546 ASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQE 605
+ P + + + ++ K EK +
Sbjct: 249 SKP--------------------------------KSDRGSHSHSRSRSKDEYEKSRSRS 276
Query: 606 HERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRS 665
R +E+ + K R + + R + S P SR S SR +SRS
Sbjct: 277 RSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRS 336
Query: 666 RSRS 669
RSRS
Sbjct: 337 RSRS 340
Score = 56.6 bits (135), Expect = 7e-08
Identities = 57/207 (27%), Positives = 86/207 (41%), Gaps = 26/207 (12%)
Query: 463 YGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSR 522
Y +R+ + + R R + + R S+S S SRSRS RSRS S S+SR
Sbjct: 156 YSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSR 215
Query: 523 SRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRM 582
SRS S+S+S S S ++ G +++ + +KPK
Sbjct: 216 SRSISKSRSRSRSRSK------------GRSRSRSKGRKSRSKSKSKPK----------S 253
Query: 583 QKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYS 642
+ + ++ K EK + R +E+ I+ K R R +
Sbjct: 254 DRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG----KGDIKSKSRSRSQSRSNSPLPVPP 309
Query: 643 RQSRSPSPRYSREYSSSRRRSRSRSRS 669
++RS SP R S SR RSRS+SRS
Sbjct: 310 SKARSVSPPPKRATSRSRSRSRSKSRS 336
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/221 (29%), Positives = 89/221 (40%), Gaps = 21/221 (9%)
Query: 219 ADLNKQATTYGMAD----GDFVRMLRKDKEEAEAIKHAKA-LEEEKAMYSGRRSRRQRRE 273
AD +K+ T G+ + D R L DK + I L E+K S RRS R
Sbjct: 139 ADAHKERTNEGVIEFRSYSDMKRAL--DKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRS 196
Query: 274 FREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFG 333
R R R S S R RS S S SRSRS+ R + + S
Sbjct: 197 RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG-RKSRSKSKSKPKSDR 255
Query: 334 GSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR 393
GS + + + + + +P + G + +R RS S S+S S +R
Sbjct: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENG--KGDIKSKSRSRSQSRSNSPLPVPPSKAR 313
Query: 394 SSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSR 434
S S R+ +RSRSRS S+SRSRSR SR
Sbjct: 314 SVSPPPKRAT-----------SRSRSRSRSKSRSRSRSSSR 343
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 90.1 bits (222), Expect = 6e-18
Identities = 78/213 (36%), Positives = 97/213 (45%), Gaps = 28/213 (13%)
Query: 385 SASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSG 444
S SR+ SSRS SRS S SR + + RSRSR++SRSRSR R YSR R
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD----- 58
Query: 445 GGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPS 503
Y + A R YG R R R G RY RGG R W+ S
Sbjct: 59 --------YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGG----------YRPVWNRRHS 100
Query: 504 RSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPA 560
RS RSRS SP S S RSRSRSR S R +R ++SP + K +
Sbjct: 101 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPYSKSPVSKRRGS 159
Query: 561 AGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
K+T A+ +L + LK + Q+ F+ D
Sbjct: 160 QEKQTKKAEGELQEESPLKSKSQEEPKDTFEHD 192
Score = 73.2 bits (178), Expect = 7e-13
Identities = 71/193 (36%), Positives = 93/193 (48%), Gaps = 26/193 (13%)
Query: 364 GPAPGRNASARRRSSSSSSSSSASRTSSS----RSSSRSSSRSRRGGGYYRSGRHARSRS 419
G + R+ S+R +S S SSS S SR+ S RS SR+ SRSR R ++R
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRS-----RDRMYSRDYR 56
Query: 420 RSWSRSRSRSRRYS-RSRSRGRRHSGGG--SRDGH------RYSRSPARRG---GYGPRR 467
R + +R+ R Y R R RG GGG R G+ R+SRSP RRG P+R
Sbjct: 57 RDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSPKR 115
Query: 468 RSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS 527
RS S S R RR R R SS SRSS SP S+S R S ++
Sbjct: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSS---SP-YSKSPVSKRRGSQEKQTKKAEGEL 171
Query: 528 RSQSPSPSPAREK 540
+ +SP S ++E+
Sbjct: 172 QEESPLKSKSQEE 184
Score = 48.1 bits (113), Expect = 3e-05
Identities = 74/262 (28%), Positives = 98/262 (37%), Gaps = 27/262 (10%)
Query: 288 SYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAA 347
S +R S ++ KR S S + SRSRSR R+ + + +
Sbjct: 19 SSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRD----YRRDYRNNRAMRRPYGYRGR 74
Query: 348 ASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR--SSSRSSSRSRRG 405
G G GG P N RR S S S SR+ R SS RS SRSRR
Sbjct: 75 GRGYYQG-GGGRYHRGGYRPVWN---RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 130
Query: 406 GGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGP 465
YRS R RS S SRS S + S+ RG + +G SP
Sbjct: 131 ---YRSSRSPRSSS---SRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPL------- 177
Query: 466 RRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS-HSPSP-SQSRS 523
+S+S+ D + + S + + P S RS HSPSP + S
Sbjct: 178 --KSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPS 235
Query: 524 RSRSRSQSPSPSPAREKLTRPA 545
+S S S +P S P+
Sbjct: 236 QSSSCSDAPMLSTVHSAKNTPS 257
Score = 44.7 bits (104), Expect = 3e-04
Identities = 100/463 (21%), Positives = 166/463 (35%), Gaps = 84/463 (18%)
Query: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
+++ ++ S +RSR R RR +R R SP S + R S PY +SP
Sbjct: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSS---SPYSKSPVSKRRG 158
Query: 311 SRSRSRSPTPGR-------------EEKITFITSFGGS-DEEAAAAAAAAAASGVTTGKP 356
S+ + G E K TF S DE ++A +
Sbjct: 159 SQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYD 218
Query: 357 PAPPQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSG 412
+P P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 219 XSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG 278
Query: 413 RHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR--RGGYGPRRRSR 470
S RYS S++ H RSPA+ PR SR
Sbjct: 279 ----------------SSRYSPSQNSPIHHIPS--------RRSPAKTIAPQNAPRDESR 314
Query: 471 SRS----HSGDR-YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRS 525
RS GD+ + G+ L+ + SR R + + S + R+
Sbjct: 315 GRSSFYPDGGDQETAKTGKFLKRFTDEESR---VFLLDRGNTRDKEASKEKGSEKGRAEG 371
Query: 526 RSRSQSPSPSPAREKLTRPAASPAVGEKLKKTE----------PAAGKETGAAKPKLTPQ 575
Q + ++ + + + G+ ++TE GK A + T +
Sbjct: 372 EWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEE 431
Query: 576 EKLKLRMQKALN--------RQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKER 627
E LK + + +L R+ K DK ++++ +++ E + +I +K +
Sbjct: 432 EGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVK-K 490
Query: 628 ERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
E + E+ + E+ SP + + +R +S R SP
Sbjct: 491 ETQSPEQVKSEKLKDLFDYSPPLHKNLD---AREKSTFREESP 530
Score = 35.0 bits (79), Expect = 0.23
Identities = 52/193 (26%), Positives = 74/193 (38%), Gaps = 78/193 (40%)
Query: 509 TRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAA 568
+ SRSHS S+S+SRS+S S+S S S +R+K R
Sbjct: 4 SNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYR------------------------- 35
Query: 569 KPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE 628
+R + ++++M +++ R R + RAM R + R
Sbjct: 36 ------------------SRSRTYSRSRSRDRMYSRDYRRDYRNN--RAMRRPYGYRGRG 75
Query: 629 R-----------REKEREEWERQYSR-----QSRSPSP------------RYSREYSSSR 660
R R R W R++SR +SRS SP R R Y SSR
Sbjct: 76 RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR 135
Query: 661 --RRSRSRSRSPH 671
R S SRS SP+
Sbjct: 136 SPRSSSSRSSSPY 148
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/87 (22%), Positives = 47/87 (54%), Gaps = 8/87 (9%)
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMK-ERERREKEREEWERQYSRQSRSP- 648
K + A +E++ ++E+++ +++ LR + +R + R+E+ +E + + SR+SR
Sbjct: 662 KDTRLAGEERVFKEENQKGDKK--LRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSR 719
Query: 649 ----SPRYSREYSSSRRRSRSRSRSPH 671
+P+ +EY S + S+ + H
Sbjct: 720 KQEKTPKDYKEYKSYKDDSKHKREQDH 746
Score = 31.2 bits (69), Expect = 3.3
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 4/70 (5%)
Query: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS 663
+ H + + + + R R++R + R R YSR SRS YSR+Y R +
Sbjct: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRS---RTYSR-SRSRDRMYSRDYRRDYRNN 62
Query: 664 RSRSRSPHYR 673
R+ R YR
Sbjct: 63 RAMRRPYGYR 72
Score = 30.4 bits (67), Expect = 5.6
Identities = 19/30 (63%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 645 SRSPSPRY-SREYSSSRRRSRSRSRSPHYR 673
SRS S R SR SSSR RSRS SR YR
Sbjct: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYR 35
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 88.6 bits (218), Expect = 2e-17
Identities = 85/224 (37%), Positives = 105/224 (46%), Gaps = 37/224 (16%)
Query: 375 RRSSSSSSSSSASRT-SSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433
R +S S SS S SR+ SSSRS SRS SR +R Y S RSRSR++SRSRSR R YS
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR----YSS----RSRSRTYSRSRSRDRMYS 54
Query: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSS 492
R R R++ G R YG R R R G RY RGG
Sbjct: 55 RDYRRDYRNNRG-------------MRRPYGYRGRGRGYYQGGGGRYHRGG--------- 92
Query: 493 RSRSSWSLSPSRSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
R W+ SRS RSRS SP S S RSRSRSR S R +R ++SP
Sbjct: 93 -YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPY 150
Query: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
+ K + K+T A+ + + LK + Q+ F+ D
Sbjct: 151 SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194
Score = 56.2 bits (134), Expect = 9e-08
Identities = 108/487 (22%), Positives = 187/487 (38%), Gaps = 84/487 (17%)
Query: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
+++ ++ S +RSR R RR +R R SP S + R S Y S S E
Sbjct: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 163
Query: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359
+++ P E K TF S DE ++A + + +P
Sbjct: 164 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223
Query: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 224 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSR 283
Query: 416 RSRSRSWSRSRSRSRRYS----------RSRSRGRR--HSGGGSRDGHR---YSRSPARR 460
S S++ SRR R SRGR + GG ++ + + +SP
Sbjct: 284 YSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLH 343
Query: 461 GGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP------SRSRSLTRSR-- 512
R +S R S R + + S R ++P +R SLT+ R
Sbjct: 344 KNLDAREKSTFREESPLRIK-----MIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLL 398
Query: 513 ------------------SHSPSPSQSRSRSRSRSQS--PSPSPAREKLTRPAASPAVGE 552
H P S+S S S Q +E+ + AA + E
Sbjct: 399 ASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM-TLNE 457
Query: 553 KLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612
+ + A + + K +P+ ++ + + R K + A +E++ ++E+++ +++
Sbjct: 458 RFTSYQKATEEHSTRQK---SPEIHRRIDISPSTLR--KHTRLAGEERVFKEENQKGDKK 512
Query: 613 DELRAMARKIRMK-ERERREKEREEWERQYSRQS-----RSPSPRYSREYSSSRRRSRSR 666
LR + +R +R R+E+ +E + + SR+S + +P+ +EY S + S+ +
Sbjct: 513 --LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570
Query: 667 SRSPHYR 673
H R
Sbjct: 571 REQDHSR 577
Score = 32.7 bits (73), Expect = 1.1
Identities = 50/193 (25%), Positives = 73/193 (37%), Gaps = 76/193 (39%)
Query: 509 TRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAA 568
+ SRSHS S+S+SRS+S S+S S S +R+K
Sbjct: 4 SNSRSHS---SRSKSRSQSSSRSRSRSHSRKK---------------------------- 32
Query: 569 KPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE 628
+ +R + ++++M +++ R R + R M R + R
Sbjct: 33 -------------RYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNN--RGMRRPYGYRGRG 77
Query: 629 R-----------REKEREEWERQYSR-----QSRSPSP------------RYSREYSSSR 660
R R R W R++SR +SRS SP R R Y SSR
Sbjct: 78 RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR 137
Query: 661 --RRSRSRSRSPH 671
R S SRS SP+
Sbjct: 138 SPRSSSSRSSSPY 150
Score = 32.0 bits (71), Expect = 1.9
Identities = 18/53 (33%), Positives = 25/53 (47%)
Query: 616 RAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
R+ +R + + R + R +SR+ R S SR YS SR R R SR
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR 55
Score = 30.0 bits (66), Expect = 7.3
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)
Query: 409 YRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRR 468
+ S + A + +S RR S S R+H+ + R + ++G R
Sbjct: 459 FTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEE--RVFKEENQKGDKKLRCD 516
Query: 469 SRSRSHSGDRYRR-------GGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQS 521
S H DR R+ +G R S SR + +S H Q
Sbjct: 517 SADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKRE--QD 574
Query: 522 RSRSRSRSQSPSPSPAREK 540
SRS S S SPS +RE+
Sbjct: 575 HSRSSSSSASPSSPSSREE 593
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 88.6 bits (218), Expect = 2e-17
Identities = 85/224 (37%), Positives = 105/224 (46%), Gaps = 37/224 (16%)
Query: 375 RRSSSSSSSSSASRT-SSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433
R +S S SS S SR+ SSSRS SRS SR +R Y S RSRSR++SRSRSR R YS
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR----YSS----RSRSRTYSRSRSRDRMYS 54
Query: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSS 492
R R R++ G R YG R R R G RY RGG
Sbjct: 55 RDYRRDYRNNRG-------------MRRPYGYRGRGRGYYQGGGGRYHRGG--------- 92
Query: 493 RSRSSWSLSPSRSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
R W+ SRS RSRS SP S S RSRSRSR S R +R ++SP
Sbjct: 93 -YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPY 150
Query: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
+ K + K+T A+ + + LK + Q+ F+ D
Sbjct: 151 SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194
Score = 42.4 bits (98), Expect = 0.001
Identities = 91/431 (21%), Positives = 156/431 (36%), Gaps = 80/431 (18%)
Query: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
+++ ++ S +RSR R RR +R R SP S + R S Y S S E
Sbjct: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 163
Query: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359
+++ P E K TF S DE ++A + + +P
Sbjct: 164 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223
Query: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 224 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG--- 280
Query: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR--RGGYGPRRRSRSRS 473
S RYS S++ H RSPA+ PR SR RS
Sbjct: 281 -------------SSRYSPSQNSPIHHIPS--------RRSPAKTIAPQNAPRDESRGRS 319
Query: 474 ----HSGDR-YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSR 528
GD+ + G+ L+ + SR R + + S + R+
Sbjct: 320 SFYPDGGDQETAKTGKFLKRFTDEESR---VFLLDRGNTRDKEASKEKGSEKGRAEGEWE 376
Query: 529 SQSPSPSPAREKLTRPAASPAVGEKLKKTE----------PAAGKETGAAKPKLTPQEKL 578
Q + ++ + + + G+ ++TE GK A + T +E L
Sbjct: 377 DQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGL 436
Query: 579 KLRMQKAL--NRQ---FKADKK---------AAQEKMIQQEHERQEREDELRAMARKIRM 624
K + + +L NR+ F+ +K + + +H+ +++ E + ++ +
Sbjct: 437 KYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 496
Query: 625 KERERREKERE 635
E+ + EK ++
Sbjct: 497 PEQVKSEKLKD 507
Score = 33.5 bits (75), Expect = 0.66
Identities = 21/89 (23%), Positives = 49/89 (55%), Gaps = 8/89 (8%)
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMK-ERERREKEREEWERQYSRQS---- 645
K + A +E++ ++E+++ +++ LR + +R +R R+E+ +E + + SR+S
Sbjct: 664 KHTRLAGEERVFKEENQKGDKK--LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSR 721
Query: 646 -RSPSPRYSREYSSSRRRSRSRSRSPHYR 673
+ +P+ +EY S + S+ + H R
Sbjct: 722 KQEKTPKDYKEYKSYKDDSKHKREQDHSR 750
Score = 32.7 bits (73), Expect = 1.1
Identities = 50/193 (25%), Positives = 73/193 (37%), Gaps = 76/193 (39%)
Query: 509 TRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAA 568
+ SRSHS S+S+SRS+S S+S S S +R+K
Sbjct: 4 SNSRSHS---SRSKSRSQSSSRSRSRSHSRKK---------------------------- 32
Query: 569 KPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE 628
+ +R + ++++M +++ R R + R M R + R
Sbjct: 33 -------------RYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNN--RGMRRPYGYRGRG 77
Query: 629 R-----------REKEREEWERQYSR-----QSRSPSP------------RYSREYSSSR 660
R R R W R++SR +SRS SP R R Y SSR
Sbjct: 78 RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR 137
Query: 661 --RRSRSRSRSPH 671
R S SRS SP+
Sbjct: 138 SPRSSSSRSSSPY 150
Score = 32.0 bits (71), Expect = 1.9
Identities = 18/53 (33%), Positives = 25/53 (47%)
Query: 616 RAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
R+ +R + + R + R +SR+ R S SR YS SR R R SR
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR 55
Score = 32.0 bits (71), Expect = 1.9
Identities = 87/421 (20%), Positives = 144/421 (34%), Gaps = 67/421 (15%)
Query: 176 EKAAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDF 235
+K A K + E E D++ + D E + N + D ++ Y F
Sbjct: 357 DKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE-GDDTEETEDYRQ----F 411
Query: 236 VRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRRE---FREKRLRGRKISPPSYA-R 291
+ + D+ ++ A + EEE Y + S + RE FRE++ K+ Y
Sbjct: 412 RKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEK--NYKLKETGYVVE 469
Query: 292 RDSPTYDPYKRSPSESSSES-RSRSRSPTPGREEKITFITSFGGS--------------D 336
R S T D +K S + + ++SP + EK+ + + +
Sbjct: 470 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 529
Query: 337 EEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRS-- 394
E A+ S K P P + + + R +S+ S + RS
Sbjct: 530 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 589
Query: 395 -------SSRSSSRS----------RRGGGYYRSG-----------RHARSRSRSWSRSR 426
+S+S+S S Y++S + A + +S
Sbjct: 590 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSP 649
Query: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRR----- 481
RR S S R+H+ + R + ++G R S H DR R+
Sbjct: 650 EIHRRIDISPSTLRKHTRLAGEE--RVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE 707
Query: 482 --GGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPARE 539
+G R S SR + +S H Q SRS S S SPS +RE
Sbjct: 708 RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKRE--QDHSRSSSSSASPSSPSSRE 765
Query: 540 K 540
+
Sbjct: 766 E 766
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 87.8 bits (216), Expect = 3e-17
Identities = 100/318 (31%), Positives = 133/318 (41%), Gaps = 31/318 (9%)
Query: 240 RKDKEEAEAIKHA---KALEEEKA--MYSGRRSRRQRREFREKRLRGRKISPPSYARRDS 294
+K K+ ++ KH KA EEK+ SG +S+++++ R+K K S P+ + R
Sbjct: 676 KKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKK----NKSSAPADSERGP 731
Query: 295 PTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTG 354
P SP + R R R+ + + G +E +++ G
Sbjct: 732 KPEPPGSGSP----APPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG-RKH 786
Query: 355 KPPAPPQPGGPAPGRNASAR--RRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSG 412
K PP G S+R RS SS + SS R +S S+ SG
Sbjct: 787 KGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSG 846
Query: 413 -RHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSR----SPARRGGYGPR- 466
H+RSRSRS R S RS R S S D YSR S Y R
Sbjct: 847 SEHSRSRSRSGRRHSSH-----RSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRS 901
Query: 467 RRSRSRSHSGD--RYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSR 524
RR RSH D Y + H S S +SLS S+SRS RSRSH+ S+SR R
Sbjct: 902 RRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRS--RSRSHTRERSRSRGR 959
Query: 525 SRSRSQSPSPSPAREKLT 542
SRS S S S S R + T
Sbjct: 960 SRSSSCSRSRSKRRSRST 977
Score = 69.7 bits (169), Expect = 8e-12
Identities = 109/410 (26%), Positives = 156/410 (38%), Gaps = 91/410 (22%)
Query: 270 QRREFREKRLRGRKISPPSYARRDSP---TYDPYKRSPSESSSE----------SRSRSR 316
QRR ++ R S PS DS ++ +++SPS+ S E SRSRSR
Sbjct: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR 855
Query: 317 SP---TPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASA 373
S + R + ++ +S S +++ + + + + +
Sbjct: 856 SGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDY---------------SDR 900
Query: 374 RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433
RR S S S S +SS+ S+ S Y S +RSRSRS +R RSRSR S
Sbjct: 901 SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
Query: 434 R----SRSRGRRHSGGG-----------SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDR 478
R SRSR +R S SRD R +RSP++R G R RS H
Sbjct: 961 RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSG----SRKRSWGHESPE 1016
Query: 479 YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPS---------------PSQSRS 523
R GR RS+ S SP RS R P PSQ+ +
Sbjct: 1017 ERHSGR----RDFIRSKIYRSQSPHYFRS---GRGEGPGKKDDGRGDDSKATGPPSQNSN 1069
Query: 524 RSRSRSQSPSPSP----------AREKL--TRPAASPAVGEKLKKTEPAAGKE-----TG 566
R SP EK+ + P+V E+++ T AG + G
Sbjct: 1070 IGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQG 1129
Query: 567 AAKPKLTPQ--EKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDE 614
PKL P K L + L K +KK + + + E + Q +E
Sbjct: 1130 YFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEE 1179
Score = 52.4 bits (124), Expect = 1e-06
Identities = 85/389 (21%), Positives = 133/389 (34%), Gaps = 69/389 (17%)
Query: 350 GVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSS--------ASRTSSSRSSSRS-SS 400
G+ G+P + GG R++ R + +S S+ S S S + + RS S
Sbjct: 605 GLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPS 664
Query: 401 RSRRGGGYYR---------SGRHAR----------SRSRSWSRSRSRSRRYSRSR----- 436
+ R G +R S +H R S++ S +S+ R +R +
Sbjct: 665 KKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAP 724
Query: 437 ---SRGRRHSGGGS------------RDGHRYSRSPARRGGYGPRRR----SRSRSHSGD 477
RG + GS +D + PA G G + S S+ H G
Sbjct: 725 ADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGR 784
Query: 478 RYR--------RGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRS 529
+++ + G + S S RS S S + R H SPSQ
Sbjct: 785 KHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEED 844
Query: 530 QSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQ 589
S +R + R +S + + A + + + + R
Sbjct: 845 SGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRH 904
Query: 590 FKA-----DKKAAQEKMIQQEHERQEREDELRAMARKIRMKERER-REKEREEWERQYSR 643
K D A K + H+ +D+ + R + R RE+ R + S
Sbjct: 905 SKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSS 964
Query: 644 QSRSPSPRYSRE---YSSSRRRSRSRSRS 669
SRS S R SR +S R RS SR RS
Sbjct: 965 CSRSRSKRRSRSTTAHSWQRSRSYSRDRS 993
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 87.4 bits (215), Expect = 4e-17
Identities = 77/213 (36%), Positives = 96/213 (45%), Gaps = 28/213 (13%)
Query: 385 SASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSG 444
S SR+ SSRS SRS S SR + + RSRSR++SRSRSR R YSR R
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD----- 58
Query: 445 GGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPS 503
Y + A R YG R R R G RY RGG R W+ S
Sbjct: 59 --------YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGG----------YRPVWNRRHS 100
Query: 504 RSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPA 560
RS RSRS SP S S RSRSRSR S R +R ++SP + K +
Sbjct: 101 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPYSKSPVSKRRGS 159
Query: 561 AGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
K+T A+ + + LK + Q+ F+ D
Sbjct: 160 QEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 192
Score = 73.6 bits (179), Expect = 6e-13
Identities = 71/193 (36%), Positives = 93/193 (48%), Gaps = 26/193 (13%)
Query: 364 GPAPGRNASARRRSSSSSSSSSASRTSSS----RSSSRSSSRSRRGGGYYRSGRHARSRS 419
G + R+ S+R +S S SSS S SR+ S RS SR+ SRSR R ++R
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRS-----RDRMYSRDYR 56
Query: 420 RSWSRSRSRSRRYS-RSRSRGRRHSGGG--SRDGH------RYSRSPARRG---GYGPRR 467
R + +R+ R Y R R RG GGG R G+ R+SRSP RRG P+R
Sbjct: 57 RDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSPKR 115
Query: 468 RSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS 527
RS S S R RR R R SS SRSS SP S+S R S ++
Sbjct: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSS---SP-YSKSPVSKRRGSQEKQTKKAEGEP 171
Query: 528 RSQSPSPSPAREK 540
+ +SP S ++E+
Sbjct: 172 QEESPLKSKSQEE 184
Score = 49.7 bits (117), Expect = 9e-06
Identities = 75/262 (28%), Positives = 99/262 (37%), Gaps = 27/262 (10%)
Query: 288 SYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAA 347
S +R S ++ KR S S + SRSRSR R+ + + +
Sbjct: 19 SSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRD----YRRDYRNNRAMRRPYGYRGR 74
Query: 348 ASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR--SSSRSSSRSRRG 405
G G GG P N RR S S S SR+ R SS RS SRSRR
Sbjct: 75 GRGYYQG-GGGRYHRGGYRPVWN---RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 130
Query: 406 GGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGP 465
YRS R RS S SRS S + S+ RG + +G SP
Sbjct: 131 ---YRSSRSPRSSS---SRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL------- 177
Query: 466 RRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS-HSPSP-SQSRS 523
+S+S+ D + + S +S + P S RS HSPSP + S
Sbjct: 178 --KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPS 235
Query: 524 RSRSRSQSPSPSPAREKLTRPA 545
+S S S +P S P+
Sbjct: 236 QSSSCSDAPMLSTVHSAKNTPS 257
Score = 44.3 bits (103), Expect = 4e-04
Identities = 99/460 (21%), Positives = 166/460 (36%), Gaps = 78/460 (16%)
Query: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
+++ ++ S +RSR R RR +R R SP S + R S Y S S E
Sbjct: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 161
Query: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359
+++ P E K TF S DE ++A + + +P
Sbjct: 162 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 221
Query: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 222 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG--- 278
Query: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR--RGGYGPRRRSRSRS 473
S RYS S++ H RSPA+ PR SR RS
Sbjct: 279 -------------SSRYSPSQNSPIHHIPS--------RRSPAKTIAPQNAPRDESRGRS 317
Query: 474 ----HSGDR-YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSR 528
GD+ + G+ L+ + SR R + + S + R+
Sbjct: 318 SFYPDGGDQETAKTGKFLKRFTDEESR---VFLLDRGNTRDKEASKEKGSEKGRAEGEWE 374
Query: 529 SQSPSPSPAREKLTRPAASPAVGEKLKKTE----------PAAGKETGAAKPKLTPQEKL 578
Q + ++ + + + G+ ++TE GK A + T +E L
Sbjct: 375 DQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGL 434
Query: 579 KLRMQKALN--------RQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERR 630
K + + +L R+ K DK ++++ +++ E + +I +K +E +
Sbjct: 435 KYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVK-KETQ 493
Query: 631 EKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
E+ + E+ SP + + +R +S R SP
Sbjct: 494 SPEQVKSEKLKDLFDYSPPLHKNLD---AREKSTFREESP 530
Score = 35.0 bits (79), Expect = 0.23
Identities = 52/193 (26%), Positives = 74/193 (38%), Gaps = 78/193 (40%)
Query: 509 TRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAA 568
+ SRSHS S+S+SRS+S S+S S S +R+K R
Sbjct: 4 SNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYR------------------------- 35
Query: 569 KPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE 628
+R + ++++M +++ R R + RAM R + R
Sbjct: 36 ------------------SRSRTYSRSRSRDRMYSRDYRRDYRNN--RAMRRPYGYRGRG 75
Query: 629 R-----------REKEREEWERQYSR-----QSRSPSP------------RYSREYSSSR 660
R R R W R++SR +SRS SP R R Y SSR
Sbjct: 76 RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR 135
Query: 661 --RRSRSRSRSPH 671
R S SRS SP+
Sbjct: 136 SPRSSSSRSSSPY 148
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/87 (22%), Positives = 47/87 (54%), Gaps = 8/87 (9%)
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMK-ERERREKEREEWERQYSRQSRSP- 648
K + A +E++ ++E+++ +++ LR + +R + R+E+ +E + + SR+SR
Sbjct: 662 KDTRLAGEERVFKEENQKGDKK--LRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSR 719
Query: 649 ----SPRYSREYSSSRRRSRSRSRSPH 671
+P+ +EY S + S+ + H
Sbjct: 720 KQEKTPKDYKEYKSYKDDSKHKREQDH 746
Score = 31.2 bits (69), Expect = 3.3
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 4/70 (5%)
Query: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS 663
+ H + + + + R R++R + R R YSR SRS YSR+Y R +
Sbjct: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRS---RTYSR-SRSRDRMYSRDYRRDYRNN 62
Query: 664 RSRSRSPHYR 673
R+ R YR
Sbjct: 63 RAMRRPYGYR 72
Score = 30.4 bits (67), Expect = 5.6
Identities = 19/30 (63%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 645 SRSPSPRY-SREYSSSRRRSRSRSRSPHYR 673
SRS S R SR SSSR RSRS SR YR
Sbjct: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYR 35
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 87.4 bits (215), Expect = 4e-17
Identities = 77/213 (36%), Positives = 97/213 (45%), Gaps = 28/213 (13%)
Query: 385 SASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSG 444
S SR+ SSRS SRS S SR + + RSRSR++SRSRSR R YSR R R++
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
Query: 445 GGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPS 503
G R YG R R R G RY RGG R W+ S
Sbjct: 64 G-------------MRRPYGYRGRGRGYYQGGGGRYHRGG----------YRPVWNRRHS 100
Query: 504 RSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPA 560
RS RSRS SP S S RSRSRSR S R +R ++SP + K +
Sbjct: 101 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPYSKSPVSKRRGS 159
Query: 561 AGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
K+T A+ + + LK + Q+ F+ D
Sbjct: 160 QEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 192
Score = 73.2 bits (178), Expect = 7e-13
Identities = 71/193 (36%), Positives = 92/193 (47%), Gaps = 26/193 (13%)
Query: 364 GPAPGRNASARRRSSSSSSSSSASRTSSS----RSSSRSSSRSRRGGGYYRSGRHARSRS 419
G + R+ S+R +S S SSS S SR+ S RS SR+ SRSR R ++R
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRS-----RDRMYSRDYR 56
Query: 420 RSWSRSRSRSRRYS-RSRSRGRRHSGGG--SRDGH------RYSRSPARRG---GYGPRR 467
R + +R R Y R R RG GGG R G+ R+SRSP RRG P+R
Sbjct: 57 RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSPKR 115
Query: 468 RSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS 527
RS S S R RR R R SS SRSS SP S+S R S ++
Sbjct: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSS---SP-YSKSPVSKRRGSQEKQTKKAEGEP 171
Query: 528 RSQSPSPSPAREK 540
+ +SP S ++E+
Sbjct: 172 QEESPLKSKSQEE 184
Score = 51.6 bits (122), Expect = 2e-06
Identities = 75/262 (28%), Positives = 99/262 (37%), Gaps = 27/262 (10%)
Query: 288 SYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAA 347
S +R S ++ KR S S + SRSRSR R+ + + + G
Sbjct: 19 SSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGY 78
Query: 348 ASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR--SSSRSSSRSRRG 405
G GG P N RR S S S SR+ R SS RS SRSRR
Sbjct: 79 YQG-----GGGRYHRGGYRPVWN---RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 130
Query: 406 GGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGP 465
YRS R RS S SRS S + S+ RG + +G SP
Sbjct: 131 ---YRSSRSPRSSS---SRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL------- 177
Query: 466 RRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS-HSPSP-SQSRS 523
+S+S+ D + + S +S + P S RS HSPSP + S
Sbjct: 178 --KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPS 235
Query: 524 RSRSRSQSPSPSPAREKLTRPA 545
+S S S +P S P+
Sbjct: 236 QSSSCSDAPMLSTVHSAKNTPS 257
Score = 42.4 bits (98), Expect = 0.001
Identities = 91/431 (21%), Positives = 156/431 (36%), Gaps = 80/431 (18%)
Query: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
+++ ++ S +RSR R RR +R R SP S + R S Y S S E
Sbjct: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 161
Query: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359
+++ P E K TF S DE ++A + + +P
Sbjct: 162 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 221
Query: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 222 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG--- 278
Query: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR--RGGYGPRRRSRSRS 473
S RYS S++ H RSPA+ PR SR RS
Sbjct: 279 -------------SSRYSPSQNSPIHHIPS--------RRSPAKTIAPQNAPRDESRGRS 317
Query: 474 ----HSGDR-YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSR 528
GD+ + G+ L+ + SR R + + S + R+
Sbjct: 318 SFYPDGGDQETAKTGKFLKRFTDEESR---VFLLDRGNTRDKEASKEKGSEKGRAEGEWE 374
Query: 529 SQSPSPSPAREKLTRPAASPAVGEKLKKTE----------PAAGKETGAAKPKLTPQEKL 578
Q + ++ + + + G+ ++TE GK A + T +E L
Sbjct: 375 DQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGL 434
Query: 579 KLRMQKAL--NRQ---FKADKK---------AAQEKMIQQEHERQEREDELRAMARKIRM 624
K + + +L NR+ F+ +K + + +H+ +++ E + ++ +
Sbjct: 435 KYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
Query: 625 KERERREKERE 635
E+ + EK ++
Sbjct: 495 PEQVKSEKLKD 505
Score = 33.5 bits (75), Expect = 0.66
Identities = 51/193 (26%), Positives = 73/193 (37%), Gaps = 78/193 (40%)
Query: 509 TRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAA 568
+ SRSHS S+S+SRS+S S+S S S +R+K R
Sbjct: 4 SNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYR------------------------- 35
Query: 569 KPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE 628
+R + ++++M +++ R R + R M R + R
Sbjct: 36 ------------------SRSRTYSRSRSRDRMYSRDYRRDYRNN--RGMRRPYGYRGRG 75
Query: 629 R-----------REKEREEWERQYSR-----QSRSPSP------------RYSREYSSSR 660
R R R W R++SR +SRS SP R R Y SSR
Sbjct: 76 RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR 135
Query: 661 --RRSRSRSRSPH 671
R S SRS SP+
Sbjct: 136 SPRSSSSRSSSPY 148
Score = 33.5 bits (75), Expect = 0.66
Identities = 21/89 (23%), Positives = 49/89 (55%), Gaps = 8/89 (8%)
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMK-ERERREKEREEWERQYSRQS---- 645
K + A +E++ ++E+++ +++ LR + +R +R R+E+ +E + + SR+S
Sbjct: 662 KHTRLAGEERVFKEENQKGDKK--LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSR 719
Query: 646 -RSPSPRYSREYSSSRRRSRSRSRSPHYR 673
+ +P+ +EY S + S+ + H R
Sbjct: 720 KQEKTPKDYKEYKSYKDDSKHKREQDHSR 748
Score = 33.1 bits (74), Expect = 0.86
Identities = 105/525 (20%), Positives = 179/525 (34%), Gaps = 77/525 (14%)
Query: 176 EKAAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDF 235
+K A K + E E D++ + D E + N + D ++ Y F
Sbjct: 355 DKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE-GDDTEETEDYRQ----F 409
Query: 236 VRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRRE---FREKRLRGRKISPPSYA-R 291
+ + D+ ++ A + EEE Y + S + RE FRE++ K+ Y
Sbjct: 410 RKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEK--NYKLKETGYVVE 467
Query: 292 RDSPTYDPYKRSPSESSSES-RSRSRSPTPGREEKITFITSFGGS--------------D 336
R S T D +K S + + ++SP + EK+ + + +
Sbjct: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 527
Query: 337 EEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRS-- 394
E A+ S K P P + + + R +S+ S + RS
Sbjct: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
Query: 395 -------SSRSSSRS----------RRGGGYYRSG-----------RHARSRSRSWSRSR 426
+S+S+S S Y++S + A + +S
Sbjct: 588 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSP 647
Query: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL 486
RR S S R+H+ + R + ++G R S H DR R+
Sbjct: 648 EIHRRIDISPSTLRKHTRLAGEE--RVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE 705
Query: 487 RHHSSSRSRSSWSLSPSRS-RSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPA 545
R S SS S ++ + +S+ R + SRS S S SP+
Sbjct: 706 RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEK 765
Query: 546 ASPAVGEKLKKTEPAAGKETGAA---KPKLT-------------PQEKLKLRMQKALNRQ 589
S E+ KT + +G A +P+ T + + + Q+ R
Sbjct: 766 ESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGR- 824
Query: 590 FKADKKAAQEKMIQQEHERQE-REDELRAMARKIRMKERERREKE 633
F K + K +++ EDE M K+R + EKE
Sbjct: 825 FNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
Score = 30.8 bits (68), Expect = 4.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS 663
+ H + + + + R R++R + R R YSR SRS YSR+Y R +
Sbjct: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRS---RTYSR-SRSRDRMYSRDYRRDYRNN 62
Query: 664 RSRSRSPHYR 673
R R YR
Sbjct: 63 RGMRRPYGYR 72
Score = 30.4 bits (67), Expect = 5.6
Identities = 19/30 (63%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 645 SRSPSPRY-SREYSSSRRRSRSRSRSPHYR 673
SRS S R SR SSSR RSRS SR YR
Sbjct: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYR 35
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 86.7 bits (213), Expect = 7e-17
Identities = 125/462 (27%), Positives = 183/462 (39%), Gaps = 56/462 (12%)
Query: 239 LRKDKEEAEAIKHAKALEEE----KAMYSGRRSRRQRREFREKRLRGRKISP-------- 286
LRK K+ + KH + + K + R S+ +R+E +++ R SP
Sbjct: 199 LRKKKKSVK--KHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHS 256
Query: 287 ------PSYARRDSPTYDPYKRSPS------ESSSESRSRSRSPTPGREEKITFITSFGG 334
PS + S + P + SP ++ S+ S SRSP+P S G
Sbjct: 257 SGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGG-------SGWG 309
Query: 335 SDEEAAAAAAAAAASGVTTGKPPAPP-QPGGPAPG-RNASARRRSSSSSSSSSASRTSSS 392
S + + + A G G +PP +P P+P R+ +A + + + S+
Sbjct: 310 SPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSA 369
Query: 393 RSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHR 452
SS R+ G G R R R RSRS S S R R R R R S
Sbjct: 370 PSSQGRGGRAAGGAGRRRRRRRRRRRSRS-SASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
Query: 453 YSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRS 511
S S + RG GP S R H G R R R +S S S + R +S
Sbjct: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG-RRGGPEGKS 487
Query: 512 RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPK 571
S SP P RS S S+SPS S +R RP SP+ KK P + + G + +
Sbjct: 488 SSRSPGP---HPRSWSSSRSPSKSRSRSAEKRPH-SPSRSPSPKK--PLSRDKDGEGRAR 541
Query: 572 LTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERRE 631
+ E + R + +R + +K ++ E R + + ++ R
Sbjct: 542 HSEAEATRARRR---SRSYSPIRKRRRDSPSFMEPRR------ITSARKRPIPYYRPSPS 592
Query: 632 KEREEWERQYSRQS--RSPSPRYSR-EYSSSRRRSRSRSRSP 670
YS +S RSPSP +S YSS +RSR+RSP
Sbjct: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP 634
Score = 85.5 bits (210), Expect = 1e-16
Identities = 101/296 (34%), Positives = 122/296 (41%), Gaps = 60/296 (20%)
Query: 263 SGRRSRRQRREFREK------RLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSR 316
+GRR RR+RR R + R RGR+ P+ R S + RS S+S S +
Sbjct: 383 AGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSR-ARSSSDSGSGRGAPGP 441
Query: 317 SPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRR 376
P PG E GG + A A PA P A GR +
Sbjct: 442 GPEPGSER------GHGGHGKRAKERPPRAR---------PASTSPSPGAHGRRGGPEGK 486
Query: 377 SSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
SSS S SSSRS S+S SRS A R S SRS S + SR +
Sbjct: 487 SSSRSPGPHPRSWSSSRSPSKSRSRS------------AEKRPHSPSRSPSPKKPLSRDK 534
Query: 437 S-RGR-RHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRR----GGRGLRHHS 490
GR RHS + R SRS Y P R+ R S S RR R + ++
Sbjct: 535 DGEGRARHSEAEATRARRRSRS------YSPIRKRRRDSPSFMEPRRITSARKRPIPYYR 588
Query: 491 SSRSRSSWSLSPSRSRSLTRSRSHSPSPSQS-----------RSRSRSRSQSPSPS 535
S S SS LS S TRS S SPSP S RSR+RS S++PSPS
Sbjct: 589 PSPSSSSSCLSSDYS---TRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPS 641
Score = 72.0 bits (175), Expect = 2e-12
Identities = 89/367 (24%), Positives = 136/367 (37%), Gaps = 57/367 (15%)
Query: 352 TTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRS 411
++ PP + R + +RR S S S+S + S + R R G R
Sbjct: 162 SSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRK 221
Query: 412 GRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRY----SRSPARRGGYGPRR 467
RH RSRS S+ +R +++ + R H+ R HR+ S SP+ Y
Sbjct: 222 RRH-RSRS-------SKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSD-- 271
Query: 468 RSRSRSHSGDRYRRGGR--GLRHHSSSRS-----RSSWSLSPSRSRSLTRSRSH------ 514
SRS S ++R GR G + S SRS S W S RS +H
Sbjct: 272 -SRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS 330
Query: 515 ------SPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP--------AVG--------- 551
PS R R ++ + +P+P ++ P ++P A G
Sbjct: 331 AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRR 390
Query: 552 --EKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609
+ ++ +A + G +P+ P + +A + + A + ER
Sbjct: 391 RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERG 450
Query: 610 EREDELRAMARKIRMKERERREKEREEWER---QYSRQSRSPSPRYSREYSSSRRRSRSR 666
RA R R + R + SRSP P + R +SSSR S+SR
Sbjct: 451 HGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGP-HPRSWSSSRSPSKSR 509
Query: 667 SRSPHYR 673
SRS R
Sbjct: 510 SRSAEKR 516
Score = 71.6 bits (174), Expect = 2e-12
Identities = 112/460 (24%), Positives = 167/460 (36%), Gaps = 52/460 (11%)
Query: 256 EEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRS 315
+++K G R R++R + G S P ++ S RS S S + R RS
Sbjct: 169 KKKKKKKGGHRRSRKKRRLESECSCGS--SSPLRKKKKSVKKHRRDRSDSGSRRKRRHRS 226
Query: 316 RSPTPGREEKI-------TFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPG 368
RS R+EK T + ++ + + +S + + P+ P G
Sbjct: 227 RSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEG 286
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
R ++R SS SR+ S S S R GG RSG H + S
Sbjct: 287 RKTGSQR--------SSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKP 338
Query: 429 SRRYSRSRSRGRRHSG-----GGSRDGHRYSRSPARRGGYGP--------RRRSRSRSH- 474
S R R + + G R + S RGG RRR R RS
Sbjct: 339 SSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRS 398
Query: 475 SGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSP 534
S RR GR + R SS SLS +RS S + S +P P R
Sbjct: 399 SASAPRRRGRRRPRPAPPRG-SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKR 457
Query: 535 SPAREKLTRPAA-SPAVGEKLKKTEPAAGKETGAAKPK----LTPQEKLKLRMQKALNRQ 589
+ R RPA+ SP+ G ++ P + + P + + K R + A R
Sbjct: 458 AKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517
Query: 590 FKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKER-------ERREKEREEWERQYS 642
+ + +K + ++ + + R A A + R + R RR+ R+ +
Sbjct: 518 HSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRIT 577
Query: 643 RQSRSPSPRYSREYSSS--------RRRSRSRSRSPHYRH 674
+ P P Y SSS RS SRS SP + H
Sbjct: 578 SARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSH 617
Score = 57.8 bits (138), Expect = 3e-08
Identities = 60/180 (33%), Positives = 72/180 (40%), Gaps = 20/180 (11%)
Query: 281 GRKISPPSYARRDSPTYDPYKRSPSESSSESRSRS---------RSPTPGREEKITFITS 331
GR+ P + SP P S S S S+SRSRS RSP+P +
Sbjct: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE 537
Query: 332 FGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARR------RSSSSSSSSS 385
EA A A + + + P P R SAR+ R S SSSSS
Sbjct: 538 GRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSC 597
Query: 386 ASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGG 445
S S+RS SRS S G Y RSR+RS SR+ S S SR SGG
Sbjct: 598 LSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPS-----YHSRSSSESGG 652
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 86.3 bits (212), Expect = 9e-17
Identities = 113/442 (25%), Positives = 172/442 (38%), Gaps = 75/442 (16%)
Query: 146 QRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEE--------ESAAEEESNSDE 197
++ +E E+ K+A+++ + T E+E+A E+ E+E E EEE E
Sbjct: 302 EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQE 361
Query: 198 DEVIPDIDVEVDVDELNQ----EQVADLNKQATT--YGMADGDFVRMLRKDKEEAEAIKH 251
EV + + EV E Q E+V D+ + + +AD + + R + E +
Sbjct: 362 MEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEA 421
Query: 252 AKALEEE-----------KAMYSGRRSRR---QRREFREKRLRGRKISPPSYARRDSPTY 297
+K LE E K++ G+ + +E EK + + P A+ P
Sbjct: 422 SKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQ-PQPQS 480
Query: 298 DPYKRSPSESSSESRSRSRS-----------PTPGREEKITFITSFGGSDEEAAAAAAAA 346
P + S+S +S+ S PTP ++ + +
Sbjct: 481 QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV 540
Query: 347 AASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGG 406
V T P + + + R + + S S S SSS+S +SSS +SS S S S G
Sbjct: 541 PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS 600
Query: 407 GYYRSGRHARSRSRSWSRSRSR-------SRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR 459
S R + S S S S S SR S SRSRSRGR H+
Sbjct: 601 S---SSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHN---------------- 641
Query: 460 RGGYGPRRRSRSRSHSGDRYRRGGRGL-RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSP 518
R R S DR RR GL R H SS+ SS S+ ++ R S S
Sbjct: 642 --------RDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
Query: 519 SQSRSRSRSRSQSPSPSPAREK 540
S + SRS+ S ++K
Sbjct: 694 SSRSGKRSSRSERDRKSDRKDK 715
Score = 48.1 bits (113), Expect = 3e-05
Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 8/174 (4%)
Query: 471 SRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQ 530
S+S + R R GR S SRSRSS S S S S + + S S S S S S S S S
Sbjct: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
Query: 531 SPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQF 590
S S S +R+ +S + + + G+ + ++ K R L R
Sbjct: 612 STSGSSSRD------SSSSTSSSSESRSRSRGRGHNRDRKHRRSVDR-KRRDTSGLERSH 664
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQ 644
K+ K + + ++ R D R+++ R +R R + + +R+ R+
Sbjct: 665 KS-SKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
Score = 30.8 bits (68), Expect = 4.3
Identities = 15/76 (19%), Positives = 37/76 (48%)
Query: 573 TPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREK 632
T ++K + +++ L Q + ++K + + + ER+ ++ ELR + +K+ + + +
Sbjct: 164 TERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWN 223
Query: 633 EREEWERQYSRQSRSP 648
E +Y R P
Sbjct: 224 EHNAKIIKYIRTKTKP 239
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 85.5 bits (210), Expect = 1e-16
Identities = 71/190 (37%), Positives = 93/190 (48%), Gaps = 19/190 (10%)
Query: 374 RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHAR-----SRSRSWSRSRSR 428
R S SS S + + S R R RH R SR RS SRSRSR
Sbjct: 13 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
Query: 429 SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRH 488
RR+ RSRSR R+ S SR+ + SRS + R R +SRS S +R RR +R
Sbjct: 73 ERRH-RSRSRERKKSRSRSRE-RKKSRSRS-------RERKKSRSRSRERKRR----IRS 119
Query: 489 HSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP 548
S SRSR + SRSR+ +RSR + R SRS S++PSP P R + T A
Sbjct: 120 RSRSRSRHR-HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQE 178
Query: 549 AVGEKLKKTE 558
A+ +L++ +
Sbjct: 179 ALARRLERAK 188
Score = 81.6 bits (200), Expect = 2e-15
Identities = 79/220 (35%), Positives = 101/220 (45%), Gaps = 33/220 (15%)
Query: 375 RRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRH-ARSRSRSWSRSRSRSRRYS 433
R +SS + R S RS SRSR R RH +RSR R SRSRSR R+ S
Sbjct: 42 RLNSSENGEDRHKRKERKSSRGRSHSRSRS-----RERRHRSRSRERKKSRSRSRERKKS 96
Query: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSR 493
RSRSR R+ S SR+ R R RSRSRS S R+R R R S SR
Sbjct: 97 RSRSRERKKSRSRSRERKR-------------RIRSRSRSRSRHRHRTRSRS-RTRSRSR 142
Query: 494 SRSSWSLSPSR-SRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGE 552
R P R SRSL SR+ SP P + R+ + ++ + R K + + E
Sbjct: 143 DRKKRIEKPRRFSRSL--SRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVE 200
Query: 553 KLKKTEPAAGKETG----------AAKPKLTPQEKLKLRM 582
K K+ E AA TG A+ ++TPQ + +M
Sbjct: 201 KQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQM 240
Score = 63.2 bits (152), Expect = 8e-10
Identities = 63/257 (24%), Positives = 94/257 (36%), Gaps = 62/257 (24%)
Query: 388 RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS 447
R S+ S +S S R R S R +R R SRGR HS S
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 448 RDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRS 507
R+ SRS R R +SRS S +R + R R SRSRS RSRS
Sbjct: 72 RERRHRSRS---------RERKKSRSRSRERKKSRSRS-RERKKSRSRSRERKRRIRSRS 121
Query: 508 LTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGA 567
+RSR + S+SR+RSRSR + ++++ +P + P G+ T
Sbjct: 122 RSRSRHRHRTRSRSRTRSRSRDR-------KKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 174
Query: 568 AKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKER 627
D A+AR++ ++
Sbjct: 175 ---------------------------------------------DAQEALARRLERAKK 189
Query: 628 ERREKEREEWERQYSRQ 644
+ ++E+E E+Q ++
Sbjct: 190 LQEQREKEMVEKQKQQE 206
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/99 (40%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
R+ S R S S S + S SRS R SRSR R +RSRSR R+RSR
Sbjct: 75 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR 134
Query: 429 SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRR 467
SR SRSR R +R R+SRS +R P R
Sbjct: 135 SRTRSRSRDRKKR-----IEKPRRFSRSLSRTPSPPPFR 168
Score = 41.2 bits (95), Expect = 0.003
Identities = 36/123 (29%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Query: 554 LKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERED 613
LK+ K+ + K K + K R ++ + K +++ R
Sbjct: 8 LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
Query: 614 ELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSR-RRSRSRSRS-PH 671
R+ R+ R + RER++ ER+ SR SRS + SR S R RR RSRSRS
Sbjct: 68 RSRSRERRHRSRSRERKKSRSRSRERKKSR-SRSRERKKSRSRSRERKRRIRSRSRSRSR 126
Query: 672 YRH 674
+RH
Sbjct: 127 HRH 129
Score = 39.7 bits (91), Expect = 0.009
Identities = 23/83 (27%), Positives = 39/83 (46%)
Query: 587 NRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSR 646
+R + ++K+++ + + R+ R +K R + RER++ ER+ SR
Sbjct: 51 DRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRS 110
Query: 647 SPSPRYSREYSSSRRRSRSRSRS 669
R R S SR R R R+RS
Sbjct: 111 RERKRRIRSRSRSRSRHRHRTRS 133
Score = 38.5 bits (88), Expect = 0.020
Identities = 34/157 (21%), Positives = 69/157 (43%), Gaps = 17/157 (10%)
Query: 524 RSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAG----KETGAAKPKLTPQEKLK 579
R S+ +S + E + +S E+L +E KE +++ + + + +
Sbjct: 13 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72
Query: 580 LRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWER 639
R ++ +R+ K + ++E+ + R+ ++ R+ +ER+RR + R
Sbjct: 73 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRS-------RERKRRIRSRSRSRS 125
Query: 640 QYSRQSRSPSPRYSR------EYSSSRRRSRSRSRSP 670
++ ++RS S SR RR SRS SR+P
Sbjct: 126 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 162
Score = 32.3 bits (72), Expect = 1.5
Identities = 35/164 (21%), Positives = 62/164 (37%), Gaps = 28/164 (17%)
Query: 237 RMLRKDKEEAEAIKHAKALEEEKAMYSGRRSR-------RQRREFREKRLRGRKISPPSY 289
R RK+++ + H+++ E+ S R R R+R++ R + +K S
Sbjct: 52 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 111
Query: 290 ARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAAS 349
R+ RS + SRSR+RS + R+++I F S
Sbjct: 112 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS-------------- 157
Query: 350 GVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR 393
+ P+PP P GRN + + + + A + R
Sbjct: 158 ---LSRTPSPP----PFRGRNTAMDAQEALARRLERAKKLQEQR 194
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 84.3 bits (207), Expect = 3e-16
Identities = 70/146 (47%), Positives = 81/146 (55%), Gaps = 19/146 (13%)
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
+ ++ R RS S SS S +S SSS SSSRS SRSR RS ++SRSRS SR RSR
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS-----RSSSSSQSRSRSSSRERSR 250
Query: 429 SRRYSRSRSRGRRHSGGGSRDGHRY---SRSPARRGGYGPRRRSRSR-SHSGDRYRRGGR 484
SR S+SRS R H G S Y S SP R R+RSRSR S SGDR +R R
Sbjct: 251 SRG-SKSRSSSRSHRGSSSPRKRSYSSSSSSPERN-----RKRSRSRSSSSGDRKKRRTR 304
Query: 485 G----LRHHSSSRSRSSWSLSPSRSR 506
RH SSS S S S S S+ +
Sbjct: 305 SRSPERRHRSSSGSSHSGSRSSSKKK 330
Score = 80.1 bits (196), Expect = 6e-15
Identities = 65/155 (41%), Positives = 76/155 (49%), Gaps = 21/155 (13%)
Query: 376 RSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRS 435
+ S+ S S SR+S SRSSSRSSS S RS +RSRS S S+SRSRS RS
Sbjct: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSS-----RSRSRSRSRSSSSSQSRSRSSSRERS 249
Query: 436 RSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSR 495
RSRG + S S + RG PR+RS S S S R S SRS
Sbjct: 250 RSRGSKSR----------SSSRSHRGSSSPRKRSYSSSSSSPERN------RKRSRSRSS 293
Query: 496 SSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQ 530
SS R+RS + R H S S S SRS S+
Sbjct: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
Score = 68.2 bits (165), Expect = 2e-11
Identities = 61/156 (39%), Positives = 75/156 (48%), Gaps = 28/156 (17%)
Query: 377 SSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
S + +S ++ +S+ RS S+SR H+RS SRS S S SRSR SR
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSS--------HSRSSSRSSSPSSSRSR----SR 228
Query: 437 SRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRS 496
SR R S SR S S R G + RS SRSH G R RS S
Sbjct: 229 SRSRSSSSSQSRS---RSSSRERSRSRGSKSRSSSRSHRGSSSPR----------KRSYS 275
Query: 497 SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSP 532
S S SP R+R +RSRS S S R + R+RS+SP
Sbjct: 276 SSSSSPERNRKRSRSRS---SSSGDRKKRRTRSRSP 308
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/249 (29%), Positives = 101/249 (40%), Gaps = 36/249 (14%)
Query: 250 KHAKALEEEKAMYSGRRSRRQRREF---------------REKRLRGRKISPPSYARRDS 294
K+AK EE+ Y G + R+ E+ ++K+ RG+ + P S +
Sbjct: 92 KYAKL--EERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVE 149
Query: 295 PTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITS---FGGSDEEAAAAAAAAAASGV 351
K S E E S+ E++ S S+EE + + S
Sbjct: 150 D-----KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
Query: 352 TTGKPPAPPQPGGPAPGRNAS-ARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYR 410
+ + +P + S +R RS SSSSS S SR+SS S S+SR +R
Sbjct: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
Query: 411 SGRHARSRSRSWSRSR-SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRS 469
R RS S S S R+R+ SRSRS S G + SRSP RR R S
Sbjct: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRS----SSSGDRKKRRTRSRSPERR-----HRSS 315
Query: 470 RSRSHSGDR 478
SHSG R
Sbjct: 316 SGSSHSGSR 324
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/149 (32%), Positives = 68/149 (45%), Gaps = 33/149 (22%)
Query: 467 RRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSR 526
RRSRS+S S HS S SRSS SPS SRS +RSRS S S SQSRSRS
Sbjct: 200 RRSRSKSRSS------------HSRSSSRSS---SPSSSRSRSRSRSRSSSSSQSRSRSS 244
Query: 527 SRSQS---------------PSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPK 571
SR +S S SP + + ++SP E+ +K + +G K +
Sbjct: 245 SRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP---ERNRKRSRSRSSSSGDRKKR 301
Query: 572 LTPQEKLKLRMQKALNRQFKADKKAAQEK 600
T + R + + + ++++K
Sbjct: 302 RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
Score = 53.9 bits (128), Expect = 5e-07
Identities = 55/151 (36%), Positives = 72/151 (47%), Gaps = 21/151 (13%)
Query: 425 SRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGR 484
++ +S R SRS+SR HS SR S SP+ R RSRSRS S + R
Sbjct: 194 NKKKSNRRSRSKSRSS-HSRSSSR-----SSSPSSSRS---RSRSRSRSSSSSQSRS--- 241
Query: 485 GLRHHSSSRSRSSWSLSPSRSR-----SLTRSRSHSPSPSQ-SRSRSRSRSQSPSPSPAR 538
R S RSRS S S S SR S R RS+S S S R+R RSRS+S S +
Sbjct: 242 --RSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299
Query: 539 EKLTRPAASPAVGEKLKKTEPAAGKETGAAK 569
++ TR + SP + +G + + K
Sbjct: 300 KRRTR-SRSPERRHRSSSGSSHSGSRSSSKK 329
Score = 50.4 bits (119), Expect = 5e-06
Identities = 78/343 (22%), Positives = 124/343 (36%), Gaps = 83/343 (24%)
Query: 91 DYTPPLLTTISPEQESDERKCNYERYRGLVQNDF--AGISEEQCLYQIYIDELYGGLQRP 148
D+ + ++ + S+ CN +Y L + G +E + + I +E G
Sbjct: 68 DWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYD-- 125
Query: 149 SEDEKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIPDIDVEV 208
E +KK + ++G V + E E+ +E+E ++ + + DEDE D ++
Sbjct: 126 -EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDE----DDADL 180
Query: 209 DVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSR 268
L+ + D NK+ S RRSR
Sbjct: 181 SKYNLDASEEEDSNKKK-------------------------------------SNRRSR 203
Query: 269 RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITF 328
+ R R R SP S R RS S SSS S+SRSRS
Sbjct: 204 SKSRS-SHSRSSSRSSSPSSSRSR--------SRSRSRSSSSSQSRSRS----------- 243
Query: 329 ITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASR 388
S E + + + + S + + + P+ + ++ R R S S SSS+
Sbjct: 244 ------SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
Query: 389 TSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRR 431
R+ SRS R RH S S S SRS S++
Sbjct: 298 RKKRRTRSRSPER-----------RHRSSSGSSHSGSRSSSKK 329
Score = 48.9 bits (115), Expect = 2e-05
Identities = 51/178 (28%), Positives = 73/178 (41%), Gaps = 43/178 (24%)
Query: 492 SRSRSSWSLSPSRSRSL-TRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAV 550
S + S S S+SRS +RS S S SPS SRSRSRSRS+S S S +R + + S +
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
Query: 551 GEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQE 610
G K+ ++ G++ P+ R + + + ER
Sbjct: 253 G---SKSRSSSRSHRGSSSPR---------------KRSYSSSSSSP---------ERNR 285
Query: 611 REDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
+ R+ + R K R R SRSP R+ SS SRS S+
Sbjct: 286 KRSRSRSSSSGDRKKRRTR---------------SRSPERRHRSSSGSSHSGSRSSSK 328
Score = 39.3 bits (90), Expect = 0.012
Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 59/185 (31%)
Query: 496 SSWSLSPSRSRSLTRSRSHSPSPSQSRS-RSRSRSQSPSPSPAREKLTRPAASPAVGEKL 554
S ++L S + +S+ S S+SRS SRS S+S SPS +R +
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSR-------------- 226
Query: 555 KKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDE 614
+ ++ Q R +
Sbjct: 227 --------------------------------------SRSRSRSSSSSQSRSRSSSRER 248
Query: 615 LRAMARKIRMKERERREKEREEWERQYSRQSRSP--SPRYSREYSSS---RRRSRSRSRS 669
R+ K R R R +R YS S SP + + SR SSS R++ R+RSRS
Sbjct: 249 SRSRGSKSRSSSRSHRGSSSPR-KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS 307
Query: 670 PHYRH 674
P RH
Sbjct: 308 PERRH 312
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 7/84 (8%)
Query: 593 DKKAAQEKMIQQE----HERQEREDELRAMARKIRM---KERERREKEREEWERQYSRQS 645
DK++ E+ + E ++ E EDE A K + +E + +K+ R SR S
Sbjct: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
Query: 646 RSPSPRYSREYSSSRRRSRSRSRS 669
S S S SSSR RSRSRSRS
Sbjct: 210 HSRSSSRSSSPSSSRSRSRSRSRS 233
Score = 33.5 bits (75), Expect = 0.66
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 582 MQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE---RREKEREEWE 638
+++ +++ + +++ E + + + + E ED+ + E E +++ R
Sbjct: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
Query: 639 RQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
+ S SRS S S S SR RSRSRS S
Sbjct: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Score = 32.3 bits (72), Expect = 1.5
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 5/116 (4%)
Query: 554 LKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERED 613
L K A +E + K K + + K R + + + +++ + + +
Sbjct: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239
Query: 614 ELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
R+ +R ER R + + R S SP R SSS R+R RSRS
Sbjct: 240 RSRSSSR-----ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRS 290
Score = 31.6 bits (70), Expect = 2.5
Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSP 650
KA A+ K ++ + E EDE +++ + +++ +E + S+ + S
Sbjct: 137 KAVGPASILKEVEDKESEGEEEDEDEDLSKY-------KLDEDEDEDDADLSKYNLDASE 189
Query: 651 RYSREYSSSRRRSRSRSRSPHYR 673
S RRSRS+SRS H R
Sbjct: 190 EEDSNKKKSNRRSRSKSRSSHSR 212
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 84.3 bits (207), Expect = 3e-16
Identities = 92/318 (28%), Positives = 135/318 (42%), Gaps = 72/318 (22%)
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
+ +R SSSS SSSS SRTSS+ S+ SSS S G SR+ S S S R
Sbjct: 504 KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGS---------SRTSSRSSSPKR 554
Query: 429 SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRH 488
+R+SRSRS + SR R + + R R R RS +S +R RR R
Sbjct: 555 KKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNR---- 610
Query: 489 HSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQ-SRSRSRSRSQSPSPSPAREKLTRPAAS 547
SPSR R +RSRS ++ SRSRSR R +
Sbjct: 611 ------------SPSRERRRSRSRSRDRRTNRASRSRSRDRRK----------------- 641
Query: 548 PAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHE 607
+ ++ + K G AK QE+ K R + + K DK+ +E+ ++E +
Sbjct: 642 --IDDQRGNLSGNSHKHKGEAK----EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQ 695
Query: 608 RQEREDELRAMARKIRMKERERREKEREEWERQYSR---------------QSRSPSPRY 652
++E +D + ++ R K + E ER +SR S+ + +
Sbjct: 696 KREEKD--------FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747
Query: 653 SREYSSSRRRSRSRSRSP 670
S+++S S RS S SP
Sbjct: 748 SKKHSGSDSSGRSSSESP 765
Score = 81.3 bits (199), Expect = 3e-15
Identities = 122/456 (26%), Positives = 180/456 (39%), Gaps = 109/456 (23%)
Query: 243 KEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKR 302
KE+ + + H K +EEEK R ++ EF K + A D + KR
Sbjct: 429 KEKEQQLLHDKQMEEEKQQTE--RVTKEMNEFIHKEQNSLSLLEAREA--DGDVVNEKKR 484
Query: 303 SPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQP 362
+P+E++S P +E K E+ + + +++SG
Sbjct: 485 TPNETTSVLE-------PKKEHK---------EKEKQGRSRSGSSSSG------------ 516
Query: 363 GGPAPGRNASARRRSSSSSS---SSSASRTSSSRSSSRSSSR-SRRGGGYYRSGRHARSR 418
SSSS+S S+S++ +SSS SSS SSR S R R RH+RSR
Sbjct: 517 --------------SSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSR 562
Query: 419 SRSWSRSRSRSRRYSRS----------RSRGRRHSGGGSRD-GHRYSRSPARRGGYGPRR 467
S + RSRSR YSR + R RR S S + R +RSP+R RR
Sbjct: 563 SPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE-----RR 617
Query: 468 RSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSH-SPSPSQSRSRSR 526
RSRSRS R RR R S SRSR + R S H + Q R + R
Sbjct: 618 RSRSRS----RDRRTNRA----SRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 527 SRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEK-LKLRMQ-K 584
SRS + + KK + +E K K +EK K Q
Sbjct: 670 SRS--------------------IDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709
Query: 585 ALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQ-YSR 643
L R+ ++++ ++ I + R + + + K K R E S+
Sbjct: 710 RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSK 769
Query: 644 QSRSPSPRYSREYS-----------SSRRRSRSRSR 668
+ ++ P++SR S S + +S+SRSR
Sbjct: 770 EKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 33.9 bits (76), Expect = 0.50
Identities = 81/418 (19%), Positives = 135/418 (32%), Gaps = 60/418 (14%)
Query: 295 PTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAA------AAA 348
PT P P S S+ R +FGG + A AA
Sbjct: 112 PTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAA 171
Query: 349 SGVTTG--KPP--APPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRR 404
G G PP P PG PAP +N R S S + + + R
Sbjct: 172 FGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRT 231
Query: 405 GGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYG 464
+ R G R + + + R + RS+ + + D GG G
Sbjct: 232 LPAWIREGLEKMEREK---QKKLEKERMEQQRSQLSKKEKKATEDA---------EGGDG 279
Query: 465 PRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRS----------------- 507
PR RS+ S D + SS + S S P S
Sbjct: 280 PRLPQRSKFDS-DEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT 338
Query: 508 ----------LTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKT 557
+T + + R +++ ++ + S A LT G +
Sbjct: 339 KMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSED 398
Query: 558 EPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRA 617
E + ++ T E+L+ R+++ ++ +K+ Q E E+Q+ E +
Sbjct: 399 E----RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 618 MARKIRMKERERREKEREEWERQ-YSRQSRSPSPRYS-----REYSSSRRRSRSRSRS 669
M I ++ E E + + + R+P+ S +E+ ++ RSRS S
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGS 512
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 84.3 bits (207), Expect = 3e-16
Identities = 92/318 (28%), Positives = 135/318 (42%), Gaps = 72/318 (22%)
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
+ +R SSSS SSSS SRTSS+ S+ SSS S G SR+ S S S R
Sbjct: 504 KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGS---------SRTSSRSSSPKR 554
Query: 429 SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRH 488
+R+SRSRS + SR R + + R R R RS +S +R RR R
Sbjct: 555 KKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNR---- 610
Query: 489 HSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQ-SRSRSRSRSQSPSPSPAREKLTRPAAS 547
SPSR R +RSRS ++ SRSRSR R +
Sbjct: 611 ------------SPSRERRRSRSRSRDRRTNRASRSRSRDRRK----------------- 641
Query: 548 PAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHE 607
+ ++ + K G AK QE+ K R + + K DK+ +E+ ++E +
Sbjct: 642 --IDDQRGNLSGNSHKHKGEAK----EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQ 695
Query: 608 RQEREDELRAMARKIRMKERERREKEREEWERQYSR---------------QSRSPSPRY 652
++E +D + ++ R K + E ER +SR S+ + +
Sbjct: 696 KREEKD--------FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747
Query: 653 SREYSSSRRRSRSRSRSP 670
S+++S S RS S SP
Sbjct: 748 SKKHSGSDSSGRSSSESP 765
Score = 81.3 bits (199), Expect = 3e-15
Identities = 122/456 (26%), Positives = 180/456 (39%), Gaps = 109/456 (23%)
Query: 243 KEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKR 302
KE+ + + H K +EEEK R ++ EF K + A D + KR
Sbjct: 429 KEKEQQLLHDKQMEEEKQQTE--RVTKEMNEFIHKEQNSLSLLEAREA--DGDVVNEKKR 484
Query: 303 SPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQP 362
+P+E++S P +E K E+ + + +++SG
Sbjct: 485 TPNETTSVLE-------PKKEHK---------EKEKQGRSRSGSSSSG------------ 516
Query: 363 GGPAPGRNASARRRSSSSSS---SSSASRTSSSRSSSRSSSR-SRRGGGYYRSGRHARSR 418
SSSS+S S+S++ +SSS SSS SSR S R R RH+RSR
Sbjct: 517 --------------SSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSR 562
Query: 419 SRSWSRSRSRSRRYSRS----------RSRGRRHSGGGSRD-GHRYSRSPARRGGYGPRR 467
S + RSRSR YSR + R RR S S + R +RSP+R RR
Sbjct: 563 SPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE-----RR 617
Query: 468 RSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSH-SPSPSQSRSRSR 526
RSRSRS R RR R S SRSR + R S H + Q R + R
Sbjct: 618 RSRSRS----RDRRTNRA----SRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 527 SRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEK-LKLRMQ-K 584
SRS + + KK + +E K K +EK K Q
Sbjct: 670 SRS--------------------IDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709
Query: 585 ALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQ-YSR 643
L R+ ++++ ++ I + R + + + K K R E S+
Sbjct: 710 RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSK 769
Query: 644 QSRSPSPRYSREYS-----------SSRRRSRSRSR 668
+ ++ P++SR S S + +S+SRSR
Sbjct: 770 EKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 33.9 bits (76), Expect = 0.50
Identities = 81/418 (19%), Positives = 135/418 (32%), Gaps = 60/418 (14%)
Query: 295 PTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAA------AAA 348
PT P P S S+ R +FGG + A AA
Sbjct: 112 PTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAA 171
Query: 349 SGVTTG--KPP--APPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRR 404
G G PP P PG PAP +N R S S + + + R
Sbjct: 172 FGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRT 231
Query: 405 GGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYG 464
+ R G R + + + R + RS+ + + D GG G
Sbjct: 232 LPAWIREGLEKMEREK---QKKLEKERMEQQRSQLSKKEKKATEDA---------EGGDG 279
Query: 465 PRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRS----------------- 507
PR RS+ S D + SS + S S P S
Sbjct: 280 PRLPQRSKFDS-DEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT 338
Query: 508 ----------LTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKT 557
+T + + R +++ ++ + S A LT G +
Sbjct: 339 KMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSED 398
Query: 558 EPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRA 617
E + ++ T E+L+ R+++ ++ +K+ Q E E+Q+ E +
Sbjct: 399 E----RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 618 MARKIRMKERERREKEREEWERQ-YSRQSRSPSPRYS-----REYSSSRRRSRSRSRS 669
M I ++ E E + + + R+P+ S +E+ ++ RSRS S
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGS 512
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 84.0 bits (206), Expect = 4e-16
Identities = 74/153 (48%), Positives = 83/153 (54%), Gaps = 31/153 (20%)
Query: 388 RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS 447
R S S R R GGG Y GR +RS R R RSRSR SRSRSR R S
Sbjct: 94 RPPDSHHSRRGPPPRRYGGGGY--GRRSRSPRR---RRRSRSR--SRSRSRSRSRS---- 142
Query: 448 RDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRS 507
RYSRS +R R RSRSRS S R R S+S+SS S+S SRSRS
Sbjct: 143 ----RYSRSKSR-----SRTRSRSRSTSKSRSAR---------RSKSKSS-SVSRSRSRS 183
Query: 508 LTRSRSHSPSP-SQSRSRSRSRSQSPSPSPARE 539
+RSRS SP P S+ S+SRSRS+SP SP E
Sbjct: 184 RSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216
Score = 70.9 bits (172), Expect = 4e-12
Identities = 57/135 (42%), Positives = 70/135 (51%), Gaps = 21/135 (15%)
Query: 445 GGSRDGHRYSRSPARR----GGYGPRRRSRS-----RSHSGDRYRRGGRGLRHHSSSRSR 495
G D H R P R GGYG RRSRS RS S R R R +S S+SR
Sbjct: 93 GRPPDSHHSRRGPPPRRYGGGGYG--RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSR 150
Query: 496 S---SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGE 552
S S S S S+SRS RS+S S S S+SRSRSRSRS+S SP P ++ ++
Sbjct: 151 SRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESK-------SR 203
Query: 553 KLKKTEPAAGKETGA 567
K+ P + +E GA
Sbjct: 204 SRSKSPPKSPEEEGA 218
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/106 (47%), Positives = 59/106 (55%), Gaps = 10/106 (9%)
Query: 357 PAPPQPGGPAPGRNASA---RRRSSSSSSSSSASRTSS--SRSSSRSSSRSR-RGGGYYR 410
P P + GG GR + + RRRS S S S S SR+ S SRS SRS +RSR R R
Sbjct: 105 PPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSR 164
Query: 411 SGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRS 456
S R ++S+S S SRSRSRS RSRSR R R+ SRS
Sbjct: 165 SARRSKSKSSSVSRSRSRS----RSRSRSRSPPPVSKRESKSRSRS 206
Score = 53.1 bits (126), Expect = 8e-07
Identities = 47/141 (33%), Positives = 63/141 (44%), Gaps = 9/141 (6%)
Query: 445 GGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSR 504
G DG AR G SR R RY GG G R S R R S S S SR
Sbjct: 77 GAVLDGRELRVQMARYGRPPDSHHSR-RGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSR 135
Query: 505 SRSLTRSR---SHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAA 561
SRS +RSR S S S ++SRSRS S+S+S S ++ + S + ++ P
Sbjct: 136 SRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPV 195
Query: 562 GKETGAAK-----PKLTPQEK 577
K ++ P +P+E+
Sbjct: 196 SKRESKSRSRSKSPPKSPEEE 216
Score = 43.1 bits (100), Expect = 8e-04
Identities = 40/109 (36%), Positives = 49/109 (44%), Gaps = 27/109 (24%)
Query: 354 GKPPAPPQPGG-----PAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSR----- 403
G PP GG +P R +R RS S S S S SR S S+S SR+ SRSR
Sbjct: 104 GPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKS 163
Query: 404 --------RGGGYYRSGRHARSRSRSWS---------RSRSRSRRYSRS 435
+ RS +RSRSRS S +SRSRS+ +S
Sbjct: 164 RSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212
Score = 40.4 bits (93), Expect = 0.005
Identities = 45/185 (24%), Positives = 74/185 (40%), Gaps = 13/185 (7%)
Query: 147 RPSEDEKKKLAEKKASIGYTY--EDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIPDI 204
R S D +++ EK +G Y D E A ++ AE+ ++ + V+
Sbjct: 24 RTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGR 83
Query: 205 DVEVDVDELNQEQVADLNKQATT---YGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAM 261
++ V + + + +++ YG G + R R + + +++ ++
Sbjct: 84 ELRVQMARYGRPPDSHHSRRGPPPRRYG--GGGYGRRSRSPRRRRRSRSRSRSRSRSRS- 140
Query: 262 YSGRRSRRQRREFREK-RLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTP 320
RSR R + R + R R R S ARR RS S S S SRSRS P
Sbjct: 141 ----RSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVS 196
Query: 321 GREEK 325
RE K
Sbjct: 197 KRESK 201
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 594 KKAAQEKMIQQEHERQEREDELRAMARKIRMKERER-REKEREEWERQYSRQSRSPSPRY 652
+++ + ++ R R+ +R R K R R R + R + + +R+S+S S
Sbjct: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176
Query: 653 SREYSSSRRRSRSRSRSP 670
SR S SR RSRSRS P
Sbjct: 177 SRSRSRSRSRSRSRSPPP 194
Score = 34.7 bits (78), Expect = 0.30
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 18/85 (21%)
Query: 606 HERQEREDELRAM------ARKIRMK-----------ERERREKEREEWERQYSRQSRSP 648
H++++ ED + AM R++R++ R R Y R+SRSP
Sbjct: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSP 122
Query: 649 SPRYSREYSSSRRRSRSRSRSPHYR 673
R R S SR RSRSRSRS + R
Sbjct: 123 RRR-RRSRSRSRSRSRSRSRSRYSR 146
Score = 33.9 bits (76), Expect = 0.50
Identities = 51/165 (30%), Positives = 58/165 (35%), Gaps = 69/165 (41%)
Query: 264 GRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE-SRSRSRSPTPGR 322
GRRSR RR R R R R RS S S S SRS+SRS T R
Sbjct: 116 GRRSRSPRRR-RRSRSRSRS------------------RSRSRSRSRYSRSKSRSRTRSR 156
Query: 323 EEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSS 382
+ ++ SARR S SS
Sbjct: 157 SR-----------------------------------------STSKSRSARRSKSKSS- 174
Query: 383 SSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRS 427
S SRS SRS SRSR S R ++SRSRS S +S
Sbjct: 175 -------SVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212
Score = 32.3 bits (72), Expect = 1.5
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 588 RQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEW-----ERQYS 642
R+ ++ ++ + + R + R+ +R RR K + R S
Sbjct: 126 RRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRS 185
Query: 643 R-QSRSPSPRYSREYSSSRRRSRSRSRSP 670
R +SRSP P RE S SR RS+S +SP
Sbjct: 186 RSRSRSPPPVSKRE-SKSRSRSKSPPKSP 213
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 84.0 bits (206), Expect = 4e-16
Identities = 66/208 (31%), Positives = 111/208 (53%), Gaps = 18/208 (8%)
Query: 480 RRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPARE 539
R+GGR R H+ S+SRSS R RS ++ RS S + S+SR + R RS+SP ++
Sbjct: 303 RKGGRS-RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 361
Query: 540 KLTRPAASPA--------VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLR-MQKALNRQF 590
+ R + S + EK+K+ E K+ + + +EK K R K +++
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMAR-KIRMKERERREKEREEWERQYSRQSRSPS 649
+ D++ +EK ++E E++ +D + + + + KERE+ + + +R+ ++SR+P
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 650 PRYS---REYSSS----RRRSRSRSRSP 670
Y+ R SSS RRRSRS SRSP
Sbjct: 482 RSYNASRRSRSSSRERRRRRSRSSSRSP 509
Score = 80.5 bits (197), Expect = 5e-15
Identities = 81/245 (33%), Positives = 116/245 (47%), Gaps = 39/245 (15%)
Query: 455 RSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSH 514
+S R+GG R RS +RS S + R R S RSRS + SRSR R RS
Sbjct: 299 KSNERKGG---RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH---NRSRSRQKDRRRSK 352
Query: 515 SPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTP 574
SP +S+SR R +S+S S S + K TR EK+K+ E K+ + +
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTR--------EKIKEKERVKEKDREKEREREKE 404
Query: 575 QEKLKLR-----MQKALNRQFKADKKAAQEKMIQQEHER-----QEREDELRAMARKIRM 624
+EK K R K + + DK+ +E+ ++EHE+ +E+E + K R
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRS 464
Query: 625 KE---RERREKEREEWERQY--SRQSRSPSP--RYSREYSSSR--------RRSRSRSRS 669
KE + +++K+ R Y SR+SRS S R R SSSR +R SRS S
Sbjct: 465 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS 524
Query: 670 PHYRH 674
P R+
Sbjct: 525 PRSRN 529
Score = 79.7 bits (195), Expect = 8e-15
Identities = 80/326 (24%), Positives = 135/326 (41%), Gaps = 30/326 (9%)
Query: 359 PPQ--PGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHAR 416
PP+ P A +R + S S+A S +S+ R RSR H R
Sbjct: 263 PPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRS---------HTR 313
Query: 417 SRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRD-GHRYSRSP-ARRGGYGPRRRSRSRSH 474
S+SRS S+S SR +R S+S+ R R H+ SR R S+SP +R RR+SRSRSH
Sbjct: 314 SKSRSSSKSHSRRKR-SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372
Query: 475 SGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSP 534
S D+ + ++ + + R R R + ++ R + R + +
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDR---EKEREREKEREKEKERGKNKDRDKEREKDREKDK 429
Query: 535 SPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADK 594
RE+ R +K K+ E KE + K +++ K + + R + A +
Sbjct: 430 EKDRER-EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488
Query: 595 KAAQEKMIQQEHERQE-----------REDELRAMARKIRMKERERREKEREEWERQYSR 643
++ ++ + + R+ + + R K+ ++REKER+ + R
Sbjct: 489 RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRER 548
Query: 644 QSRSPSPRYSREYSSSRRRSRSRSRS 669
+ RS S R S + + S S
Sbjct: 549 E-RSTSMRKSSNDRDGKEKLEKNSTS 573
Score = 57.0 bits (136), Expect = 6e-08
Identities = 72/360 (20%), Positives = 115/360 (31%), Gaps = 42/360 (11%)
Query: 242 DKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYK 301
+++ + H ++ + RR R Q + R R S RR +
Sbjct: 302 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKH--RSRSHNRSRSRQKDRRRSKSPHKKRS 359
Query: 302 RSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQ 361
+S S SRS SR EKI D E
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE------------------- 400
Query: 362 PGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRS 421
R + + R + R R R H + R +
Sbjct: 401 -------REKEREKEKERGKNKDRDKEREKDREKDKEKDRERE-----REKEHEKDRDKE 448
Query: 422 WSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRR 481
+ + + + + RS+ R + SR+P R R RS SR R R
Sbjct: 449 KEKEQDKEKEREKDRSK----EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504
Query: 482 GGRGLRHHSSSRSRSSWSLSP----SRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPA 537
R R + + +SS S SP + + + R H S + R RS S +S +
Sbjct: 505 SSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI-SERRERERSTSMRKSSNDRDG 563
Query: 538 REKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAA 597
+EKL + + S E K+ + + KE T + K++ LN + + K A
Sbjct: 564 KEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEA 623
Score = 45.4 bits (106), Expect = 2e-04
Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 149 SEDEKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIPDIDVEV 208
S D++K EK E V E ++ E+ E+E E+E ++D D E
Sbjct: 373 SRDKRKDTREK------IKEKERVKEKDREKEREREKEREKEKERGKNKDR-----DKER 421
Query: 209 DVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSR 268
+ D +++ D ++ D D + +DKE+ +K ++E++ ++SR
Sbjct: 422 EKDR-EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK--KDKKSR 478
Query: 269 RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEK 325
R + R R R S RR + RSP S + R SRSP+P K
Sbjct: 479 TPPRSYNASR-RSRSSSRERRRRRSRSS----SRSPRTSKTIKRKSSRSPSPRSRNK 530
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 84.0 bits (206), Expect = 4e-16
Identities = 66/208 (31%), Positives = 111/208 (53%), Gaps = 18/208 (8%)
Query: 480 RRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPARE 539
R+GGR R H+ S+SRSS R RS ++ RS S + S+SR + R RS+SP ++
Sbjct: 187 RKGGRS-RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 245
Query: 540 KLTRPAASPA--------VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLR-MQKALNRQF 590
+ R + S + EK+K+ E K+ + + +EK K R K +++
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMAR-KIRMKERERREKEREEWERQYSRQSRSPS 649
+ D++ +EK ++E E++ +D + + + + KERE+ + + +R+ ++SR+P
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 650 PRYS---REYSSS----RRRSRSRSRSP 670
Y+ R SSS RRRSRS SRSP
Sbjct: 366 RSYNASRRSRSSSRERRRRRSRSSSRSP 393
Score = 80.5 bits (197), Expect = 5e-15
Identities = 81/245 (33%), Positives = 116/245 (47%), Gaps = 39/245 (15%)
Query: 455 RSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSH 514
+S R+GG R RS +RS S + R R S RSRS + SRSR R RS
Sbjct: 183 KSNERKGG---RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH---NRSRSRQKDRRRSK 236
Query: 515 SPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTP 574
SP +S+SR R +S+S S S + K TR EK+K+ E K+ + +
Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTR--------EKIKEKERVKEKDREKEREREKE 288
Query: 575 QEKLKLR-----MQKALNRQFKADKKAAQEKMIQQEHER-----QEREDELRAMARKIRM 624
+EK K R K + + DK+ +E+ ++EHE+ +E+E + K R
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRS 348
Query: 625 KE---RERREKEREEWERQY--SRQSRSPSP--RYSREYSSSR--------RRSRSRSRS 669
KE + +++K+ R Y SR+SRS S R R SSSR +R SRS S
Sbjct: 349 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS 408
Query: 670 PHYRH 674
P R+
Sbjct: 409 PRSRN 413
Score = 79.7 bits (195), Expect = 8e-15
Identities = 80/326 (24%), Positives = 135/326 (41%), Gaps = 30/326 (9%)
Query: 359 PPQ--PGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHAR 416
PP+ P A +R + S S+A S +S+ R RSR H R
Sbjct: 147 PPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRS---------HTR 197
Query: 417 SRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRD-GHRYSRSP-ARRGGYGPRRRSRSRSH 474
S+SRS S+S SR +R S+S+ R R H+ SR R S+SP +R RR+SRSRSH
Sbjct: 198 SKSRSSSKSHSRRKR-SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256
Query: 475 SGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSP 534
S D+ + ++ + + R R R + ++ R + R + +
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDR---EKEREREKEREKEKERGKNKDRDKEREKDREKDK 313
Query: 535 SPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADK 594
RE+ R +K K+ E KE + K +++ K + + R + A +
Sbjct: 314 EKDRER-EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372
Query: 595 KAAQEKMIQQEHERQE-----------REDELRAMARKIRMKERERREKEREEWERQYSR 643
++ ++ + + R+ + + R K+ ++REKER+ + R
Sbjct: 373 RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRER 432
Query: 644 QSRSPSPRYSREYSSSRRRSRSRSRS 669
+ RS S R S + + S S
Sbjct: 433 E-RSTSMRKSSNDRDGKEKLEKNSTS 457
Score = 57.0 bits (136), Expect = 6e-08
Identities = 72/360 (20%), Positives = 115/360 (31%), Gaps = 42/360 (11%)
Query: 242 DKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYK 301
+++ + H ++ + RR R Q + R R S RR +
Sbjct: 186 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKH--RSRSHNRSRSRQKDRRRSKSPHKKRS 243
Query: 302 RSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQ 361
+S S SRS SR EKI D E
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE------------------- 284
Query: 362 PGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRS 421
R + + R + R R R H + R +
Sbjct: 285 -------REKEREKEKERGKNKDRDKEREKDREKDKEKDRERE-----REKEHEKDRDKE 332
Query: 422 WSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRR 481
+ + + + + RS+ R + SR+P R R RS SR R R
Sbjct: 333 KEKEQDKEKEREKDRSK----EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388
Query: 482 GGRGLRHHSSSRSRSSWSLSP----SRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPA 537
R R + + +SS S SP + + + R H S + R RS S +S +
Sbjct: 389 SSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI-SERRERERSTSMRKSSNDRDG 447
Query: 538 REKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAA 597
+EKL + + S E K+ + + KE T + K++ LN + + K A
Sbjct: 448 KEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEA 507
Score = 45.4 bits (106), Expect = 2e-04
Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 149 SEDEKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIPDIDVEV 208
S D++K EK E V E ++ E+ E+E E+E ++D D E
Sbjct: 257 SRDKRKDTREK------IKEKERVKEKDREKEREREKEREKEKERGKNKDR-----DKER 305
Query: 209 DVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSR 268
+ D +++ D ++ D D + +DKE+ +K ++E++ ++SR
Sbjct: 306 EKDR-EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK--KDKKSR 362
Query: 269 RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEK 325
R + R R R S RR + RSP S + R SRSP+P K
Sbjct: 363 TPPRSYNASR-RSRSSSRERRRRRSRSS----SRSPRTSKTIKRKSSRSPSPRSRNK 414
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 83.6 bits (205), Expect = 6e-16
Identities = 72/306 (23%), Positives = 120/306 (39%), Gaps = 17/306 (5%)
Query: 367 PGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSR 426
PG S RRR + + R +R R RR R R R R R
Sbjct: 31 PGSQESPRRRGLGQAHKDA---DGDDRERNRQKERERR--------REKRQTERETDRKR 79
Query: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL 486
R R R R R R R+ R ++ R + R+R + + R G RG
Sbjct: 80 ERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
Query: 487 -RHHSSSRSRS-SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRP 544
R R R R R R R ++ + R R +++ R++
Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
Query: 545 AASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQ 604
E+ ++ E ET + + T +E+ + R + R+ +A+++ A E+ ++
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER-EREKQAERERASERETER 258
Query: 605 EHERQEREDELRAMARKIRMKER--ERREKEREEWERQYSRQSRSPSPRYSREYSSSRRR 662
+ ER+ D R R+ + +ER +R+ + R E +R+ R+ R RE +R+R
Sbjct: 259 DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER-ERERERNRKR 317
Query: 663 SRSRSR 668
R R R
Sbjct: 318 ERERER 323
Score = 76.6 bits (187), Expect = 7e-14
Identities = 78/323 (24%), Positives = 123/323 (38%), Gaps = 29/323 (8%)
Query: 374 RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA-RSRSRSWSRSRSRSRRY 432
R R+ + + R + R R R + + RH R R R R R R
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 433 SRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL-----R 487
R R + R R+ R R G R R R R +R R+ R R
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 488 HHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQS-RSRSRSRSQSPSPSPAREKLT---- 542
+ R R + R R R + + S R R R R + R++ T
Sbjct: 174 NRQKEREREK-NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 543 -RPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKK----AA 597
R + EK + E A+ +ET K + +++ + R ++ R+ + D+K
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 598 QEKMIQQEHERQ-EREDELRAMARKIRMKERER-----------REKEREEWERQYSRQS 645
+++ +++ ERQ ERE E ++ R +ERER REKERE ++ +
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 646 RSPSPRYSREYSSSRRRSRSRSR 668
R + + RE R R R R
Sbjct: 353 RERNRQTGREGRRQAERERERER 375
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/419 (20%), Positives = 140/419 (33%), Gaps = 21/419 (5%)
Query: 265 RRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREE 324
R +++R REKR R+ RR+ + R + R R R+
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDR 115
Query: 325 KITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSS 384
+ + E T G+ Q + R R + +
Sbjct: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175
Query: 385 SASRTSSSRSSSRSSSRSRRGGGYYRSGRHA-----RSRSRSWSRSRSRSRRYSRSRSRG 439
R R +R RH+ R R R R R+ R R R
Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
Query: 440 RRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWS 499
R+ + R S R + R R R DR RR R R R +
Sbjct: 236 RKTEREREKQAERERAS--ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT-- 291
Query: 500 LSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREK---LTRPAASPAVGEKLKK 556
R R R R + R R+R R + RE+ R ++ ++
Sbjct: 292 ---ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ 348
Query: 557 TEP--AAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDE 614
TE ++TG + +E+ + R + + + + +++ +++ Q+E ERQ +D
Sbjct: 349 TEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDR 408
Query: 615 LRAMARKIRMKERERREKEREEWERQYSRQSRSPSPR-YSREYSSSRRRSRSRSRSPHY 672
++ K+RER + E R+ R+ R RE + R+ R R RS Y
Sbjct: 409 ---DGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLY 464
Score = 67.0 bits (162), Expect = 5e-11
Identities = 92/443 (20%), Positives = 154/443 (34%), Gaps = 25/443 (5%)
Query: 231 ADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYA 290
ADGD R+ + E K E ++ +R RR+ ++ KR R R+
Sbjct: 49 ADGDDRERNRQKERERRREKRQTERETDR-----KRERRREKDRHRKRDRHRERQRDREK 103
Query: 291 RRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASG 350
R+ T +R +R + R RE + G E A
Sbjct: 104 ERERQT--DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
Query: 351 VTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYR 410
T + + R+ + R S R R R R
Sbjct: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE-----R 216
Query: 411 SGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPR-RRS 469
R R R R R R+ R R + R+ R R R RR
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Query: 470 RSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRS 529
+ R DR +R R R + R R R R R+R + R R R R
Sbjct: 277 KERERQTDR-KRQRRTERDRETERKRER---QRERERERERNRKRERERERERERERQRE 332
Query: 530 QSPSPSPAREKLTRPAASPAVGEKLKKT------EPAAGKETGAAKPKLTPQEKLKLRMQ 583
RE+ R + E+ ++T + +E + + + +E+ +
Sbjct: 333 TERDREKERER-KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Query: 584 KALNRQFKADKKAAQEKMIQQEHERQ-EREDELRAMARKIRMKERERREKEREEWERQYS 642
+ +RQ + +++ +++ Q+E E+Q ERE + + + R +ERE+++ + ERQ
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTD 451
Query: 643 RQSRSPSPRYSREYSSSRRRSRS 665
RQ+ R + + R +RS
Sbjct: 452 RQAGRQRKRSTLYVNPPPRTARS 474
Score = 62.4 bits (150), Expect = 1e-09
Identities = 65/265 (24%), Positives = 103/265 (38%), Gaps = 22/265 (8%)
Query: 422 WSRSRSRSRRYSRSRSRGRRH--SGGGSRDGHRYSRSPARRGGYGPRR---RSRSRSHSG 476
+SR R S+ R R G+ H + G R+ +R RR R R R R
Sbjct: 26 FSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 477 DRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSP 536
DR+R+ R H R R R R R R ++R + R R
Sbjct: 86 DRHRKRDR---HRERQRDREK-----ERERQTDRERDRQREKERNRQKERERETEREGER 137
Query: 537 AREKLT-----RPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFK 591
R++ T R A E+ ++T+ ++T + K +EK + ++ ++ K
Sbjct: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
Query: 592 ADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERR---EKEREEWERQYSRQSRSP 648
+K + +E ER ERE E ++ +ER+R+ E+ERE+ + R
Sbjct: 198 ENKTEDRHSERGRERER-ERETETETERKRQTDRERDRQRKTEREREKQAERERASERET 256
Query: 649 SPRYSREYSSSRRRSRSRSRSPHYR 673
RE R R R R + R
Sbjct: 257 ERDKERERERDRDRDRDRRQKERER 281
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/423 (18%), Positives = 141/423 (33%), Gaps = 44/423 (10%)
Query: 146 QRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIPDID 205
QR +E E+++ +++ E EK ++ E E E+E+ +++ +
Sbjct: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 206 VEVDVD-ELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSG 264
E + + E E+ +++ + + + +++ + K E E+
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 265 RRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREE 324
R R++ RE + R R R+ RD T +R R+R R RE
Sbjct: 272 RDRRQKERERQTDRKRQRR------TERDRETERKRERQRERERERERNRKRERERERER 325
Query: 325 KITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSS 384
+ E+ R +R++ +
Sbjct: 326 ERERQRETERDREKE-----------------------------RERKRKRQTEMDRERN 356
Query: 385 SASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSG 444
+ R + R R R R R R R R + R R+ + R R
Sbjct: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416
Query: 445 GGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSR 504
R+ R S RG +++ R R R+ GR R RS+ ++P
Sbjct: 417 QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGR-------QRKRSTLYVNPPP 469
Query: 505 SRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPA-ASPAVGEKLKKTEPAAGK 563
+ + P+ R +S + P + R RPA AS ++ EP G+
Sbjct: 470 RTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGE 529
Query: 564 ETG 566
+ G
Sbjct: 530 KRG 532
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 83.6 bits (205), Expect = 6e-16
Identities = 87/266 (32%), Positives = 115/266 (43%), Gaps = 34/266 (12%)
Query: 364 GPAPGRNASARRRSSSSSSSSSASRTSS---SRSSSRSSSRSRRGGGYYRSGRHARSRSR 420
G AP + + R + S S + R S SRS SRS R R+ GR RSRSR
Sbjct: 10 GLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDN---EGRKHRSRSR 66
Query: 421 SWSRSRSRS---------------RRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGP 465
S R S + +S + R R +S D H+ + RG
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
Query: 466 RRRSRSRSH-SGDRYRRGGRG-LRHHSSSRSRSSWSLSPSRSRSLTRSRS-HSPSPSQSR 522
R RSR R H S R R+ R R SRSRS SRSRS R R S S S+SR
Sbjct: 127 RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERKRRIRSRSRSRSR 185
Query: 523 SRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKT---EPAAGKETGAAKPKLTPQEKLK 579
R R+RS+S + S +R++ R L +T P G+ T + QE L
Sbjct: 186 HRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA-----MDAQEALA 240
Query: 580 LRMQKALNRQFKADKKAAQEKMIQQE 605
R+++A Q + +K+ EK QQE
Sbjct: 241 RRLERAKKLQEQREKEMV-EKQKQQE 265
Score = 75.1 bits (183), Expect = 2e-13
Identities = 85/285 (29%), Positives = 118/285 (41%), Gaps = 53/285 (18%)
Query: 279 LRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEE 338
L K SP +++ R+ S SRSRSR R+ K SD E
Sbjct: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRE----RKRK---------SDNE 57
Query: 339 AAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRS 398
+ + + K + + ++ S SS R +SS +
Sbjct: 58 GRKHRSRSRS------KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR 111
Query: 399 SSRSRRGGGYYRSGRHARSRSRSWS-----RSRSRSRRYSRSRSRGRRHSGGGSRDGHRY 453
R R +S R RS SRS S RSRSR R+ SRSRSR R+ S SR+
Sbjct: 112 HKRKER-----KSSR-GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE---- 161
Query: 454 SRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS 513
R +SRS S +R RR +R S SRSR + SRSR+ +RSR
Sbjct: 162 --------------RKKSRSRSRERKRR----IRSRSRSRSRHR-HRTRSRSRTRSRSRD 202
Query: 514 HSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTE 558
+ R SRS S++PSP P R + T A A+ +L++ +
Sbjct: 203 RKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 247
Score = 55.8 bits (133), Expect = 1e-07
Identities = 52/215 (24%), Positives = 89/215 (41%), Gaps = 19/215 (8%)
Query: 456 SPARRGGYGPRRRS--RSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS 513
S R G P + S R + R +HH S RSRS +R R
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYS------------RSRSRSRERK 51
Query: 514 HSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLT 573
+ RSRSRS+ +++K ++ S +K E ++ K
Sbjct: 52 RKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDK----EHSSDKGRERLNSSEN 107
Query: 574 PQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKE 633
+++ K + +K+ + + ++ + + + ER++ R +K R + RER++
Sbjct: 108 GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER-KKSRSRSRERKKSR 166
Query: 634 REEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
ER+ +SRS S R + SR R+RSRSR
Sbjct: 167 SRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
Score = 55.8 bits (133), Expect = 1e-07
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 23/203 (11%)
Query: 469 SRSRSHSGDRYRRG-GRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS 527
SRSRS S +R R+ G +H S SRS+ R S+
Sbjct: 41 SRSRSRSRERKRKSDNEGRKHRSRSRSKEG------------RRHESKDKSSKKHKSEEH 88
Query: 528 RSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALN 587
+ S RE+L S GE K KE +++ + + + + R ++ +
Sbjct: 89 NDKEHSSDKGRERLN----SSENGEDRHKR-----KERKSSRGRSHSRSRSRERRHRSRS 139
Query: 588 RQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRS 647
R+ K + ++E+ + R+ ++ R+ RK R++ R R R SR +RS
Sbjct: 140 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR-TRS 198
Query: 648 PSPRYSREYSSSRRRSRSRSRSP 670
S + RR SRS SR+P
Sbjct: 199 RSRDRKKRIEKPRRFSRSLSRTP 221
Score = 33.5 bits (75), Expect = 0.66
Identities = 48/257 (18%), Positives = 91/257 (35%), Gaps = 32/257 (12%)
Query: 148 PSEDEKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDE----VIPD 203
P D+KK+ +E S + + + K + + + S S E D
Sbjct: 18 PDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKD 77
Query: 204 IDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYS 263
+ E + ++ +K ++ R RK+++ + H+++ E+ S
Sbjct: 78 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137
Query: 264 GRRSR-------RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSR 316
R R R+R++ R + +K S R+ RS + SRSR+R
Sbjct: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 197
Query: 317 SPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRR 376
S + R+++I F S + P+PP P GRN + +
Sbjct: 198 SRSRDRKKRIEKPRRFSRS-----------------LSRTPSPP----PFRGRNTAMDAQ 236
Query: 377 SSSSSSSSSASRTSSSR 393
+ + A + R
Sbjct: 237 EALARRLERAKKLQEQR 253
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 82.8 bits (203), Expect = 9e-16
Identities = 72/181 (39%), Positives = 93/181 (51%), Gaps = 16/181 (8%)
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
R++S R RS S SS SR +S S SR+ RS + +++RSRS SR R R
Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKS-----KSHRSQTRSRSRSRRRRR 1872
Query: 429 SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRH 488
S R SRS+SRGRR S + RSP R R+R RS S R+ R
Sbjct: 1873 SSR-SRSKSRGRR-----SVSKEKRKRSPKHRSKSRERKRKRSSSRDN---RKTVRARSR 1923
Query: 489 HSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP 548
S RSRS RSRS+ R RS S SPS+ RSR+ SR +S +PS +R + +P
Sbjct: 1924 TPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR-RSRTPSR-RSRTPSRRSRTPSRRSRTP 1981
Query: 549 A 549
+
Sbjct: 1982 S 1982
Score = 81.6 bits (200), Expect = 2e-15
Identities = 119/485 (24%), Positives = 190/485 (39%), Gaps = 90/485 (18%)
Query: 178 AAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVA------DLNKQATTYGMA 231
AA +E S E+E E +PD +++++N+ + D+ + +
Sbjct: 1693 AALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGI 1752
Query: 232 DGDFVRM-LRKDKEEAEAI------KHAKALEEEKAMY--------SGRRSRRQRREFRE 276
+G + + +D+ A + + +++ EEK Y + +S++ + +
Sbjct: 1753 EGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKG 1812
Query: 277 KRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSD 336
++ + R S S ++R + ++ SES S +R RS R + S
Sbjct: 1813 EKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT--------RSR 1864
Query: 337 EEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSS 396
+ ++ + + G+ + +P + +R R SSS +T R+ S
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT--VRARS 1922
Query: 397 RSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRS 456
R+ SR RS H SR R SRS R R +S S SR R SR R SR+
Sbjct: 1923 RTPSR--------RSRSHTPSRRRR-SRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRT 1973
Query: 457 PARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP---SRSRSLTRSRS 513
P+RR P RRSR+ S R R R R S R R S+S+SP RSR+ R R
Sbjct: 1974 PSRR-SRTPSRRSRTPSR---RSRTPSRRRRSRSVVR-RRSFSISPVRLRRSRTPLRRRF 2028
Query: 514 HSPSPSQSRSRSRSRSQSPSPSPAREKL------------------------TRPAASPA 549
+ RSRS R +SP +K +PA P
Sbjct: 2029 SRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT 2088
Query: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609
+ EK+ K K GA +LT EK K A K + ++ + H
Sbjct: 2089 IEEKVAK------KSGGATIEELT--EKCKQ----------IAQSKEDDDVIVNKPHVSD 2130
Query: 610 EREDE 614
E E+E
Sbjct: 2131 EEEEE 2135
Score = 65.5 bits (158), Expect = 2e-10
Identities = 76/275 (27%), Positives = 116/275 (42%), Gaps = 20/275 (7%)
Query: 371 ASARRRSSSSSSSSSAS-----RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRS 425
+S R+S SSS + + S+ + +G + RSRS+ S
Sbjct: 1773 SSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS 1832
Query: 426 RSRSR-RYSRSRSRGRRHSGGG-SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGG 483
+SR R S SRSR R+ S S SRS +RR R RS+SR +
Sbjct: 1833 EHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRK 1892
Query: 484 RGLRHHSSSRSR------SSWSLSPSRSRSLT---RSRSHSPSPSQSRSRSRSRSQSPSP 534
R +H S SR R S + R+RS T RSRSH+PS + RSRS R +S S
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-RRRRSRSVGRRRSFSI 1951
Query: 535 SPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADK 594
SP+R T P+ + +T P+ T + + + TP + + ++ +R +
Sbjct: 1952 SPSRRSRT-PSRRSRTPSRRSRT-PSRRSRTPSRRSR-TPSRRSRTPSRRRRSRSVVRRR 2008
Query: 595 KAAQEKMIQQEHERQEREDELRAMARKIRMKERER 629
+ + + R R+ R+ R + ER
Sbjct: 2009 SFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSER 2043
Score = 57.0 bits (136), Expect = 6e-08
Identities = 74/299 (24%), Positives = 107/299 (35%), Gaps = 53/299 (17%)
Query: 384 SSASRTSSSRSSSRSSSRSRRGGGY-----YRSGRHARSRSRSWSRSRSRSRRYSRSRSR 438
S+AS SS S S S Y + ++++ + +R S RSR
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 439 GRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSW 498
+R + R S S +R +R S+S+SH R R S R RSS
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSR----ARKRSSKSKSH------RSQTRSRSRSRRRRRSSR 1875
Query: 499 SLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTE 558
S S SR R SP + RS+SR + S +R+ +KT
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSP---KHRSKSRERKRKRSSSRDN--------------RKTV 1918
Query: 559 PAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAM 618
A + TP + + + + + R+ R R+
Sbjct: 1919 RARSRTPSRRSRSHTPSRR-------------RRSRSVGRRRSFSISPSRRSRTPSRRSR 1965
Query: 619 ARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRS-------RSRSP 670
R + RR + R SR+SR+PS R R S RRRS S RSR+P
Sbjct: 1966 TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS-RRRRSRSVVRRRSFSISPVRLRRSRTP 2023
Score = 37.4 bits (85), Expect = 0.046
Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 562 GKETGAAKPKLT--PQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMA 619
G++ AA P ++ P+ + ++ + + K EK ++ R + E E +
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKS-KKNKNRDKGEKEKK--- 1817
Query: 620 RKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
R ++ R +R K E R+ + +SRS + + S + S R ++RSRSRS R
Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Score = 37.0 bits (84), Expect = 0.059
Identities = 41/201 (20%), Positives = 77/201 (38%), Gaps = 27/201 (13%)
Query: 500 LSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQ-----SPSPSPAREKLTRPAASPAVGEKL 554
L P LT R+ P + R RS S P A E + + K+
Sbjct: 1737 LLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKV 1796
Query: 555 KKTEPAAGKETGAAKPKLTPQE--KLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612
K T + K K + + L+ R +++ + + K+ K+ ++ + ++ + +
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 613 DELRAMAR-KIRMKERERREKEREEWERQYSRQSRSPSPRY-SREYSSSRRRS------- 663
+ +R + R + R R + + R S++ R SP++ S+ R+RS
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916
Query: 664 -----------RSRSRSPHYR 673
RSRS +P R
Sbjct: 1917 TVRARSRTPSRRSRSHTPSRR 1937
Score = 32.3 bits (72), Expect = 1.5
Identities = 22/94 (23%), Positives = 46/94 (48%), Gaps = 9/94 (9%)
Query: 559 PAAGKETG--AAKPKLTPQEKLKLRMQKALNR------QFKADKKAAQEKMIQQEHERQE 610
P G + G AA + P E++ ++++ L+ ++K D K K + + +
Sbjct: 40 PIEGNQAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKS-RCVSVQTD 98
Query: 611 REDELRAMARKIRMKERERREKEREEWERQYSRQ 644
DE+ K K + +++K+++E E++Y RQ
Sbjct: 99 PTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQ 132
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 82.8 bits (203), Expect = 9e-16
Identities = 72/181 (39%), Positives = 93/181 (51%), Gaps = 16/181 (8%)
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
R++S R RS S SS SR +S S SR+ RS + +++RSRS SR R R
Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKS-----KSHRSQTRSRSRSRRRRR 1872
Query: 429 SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRH 488
S R SRS+SRGRR S + RSP R R+R RS S R+ R
Sbjct: 1873 SSR-SRSKSRGRR-----SVSKEKRKRSPKHRSKSRERKRKRSSSRDN---RKTVRARSR 1923
Query: 489 HSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP 548
S RSRS RSRS+ R RS S SPS+ RSR+ SR +S +PS +R + +P
Sbjct: 1924 TPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR-RSRTPSR-RSRTPSRRSRTPSRRSRTP 1981
Query: 549 A 549
+
Sbjct: 1982 S 1982
Score = 81.6 bits (200), Expect = 2e-15
Identities = 119/485 (24%), Positives = 190/485 (39%), Gaps = 90/485 (18%)
Query: 178 AAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVA------DLNKQATTYGMA 231
AA +E S E+E E +PD +++++N+ + D+ + +
Sbjct: 1693 AALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGI 1752
Query: 232 DGDFVRM-LRKDKEEAEAI------KHAKALEEEKAMY--------SGRRSRRQRREFRE 276
+G + + +D+ A + + +++ EEK Y + +S++ + +
Sbjct: 1753 EGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKG 1812
Query: 277 KRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSD 336
++ + R S S ++R + ++ SES S +R RS R + S
Sbjct: 1813 EKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT--------RSR 1864
Query: 337 EEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSS 396
+ ++ + + G+ + +P + +R R SSS +T R+ S
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT--VRARS 1922
Query: 397 RSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRS 456
R+ SR RS H SR R SRS R R +S S SR R SR R SR+
Sbjct: 1923 RTPSR--------RSRSHTPSRRRR-SRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRT 1973
Query: 457 PARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP---SRSRSLTRSRS 513
P+RR P RRSR+ S R R R R S R R S+S+SP RSR+ R R
Sbjct: 1974 PSRR-SRTPSRRSRTPSR---RSRTPSRRRRSRSVVR-RRSFSISPVRLRRSRTPLRRRF 2028
Query: 514 HSPSPSQSRSRSRSRSQSPSPSPAREKL------------------------TRPAASPA 549
+ RSRS R +SP +K +PA P
Sbjct: 2029 SRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT 2088
Query: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609
+ EK+ K K GA +LT EK K A K + ++ + H
Sbjct: 2089 IEEKVAK------KSGGATIEELT--EKCKQ----------IAQSKEDDDVIVNKPHVSD 2130
Query: 610 EREDE 614
E E+E
Sbjct: 2131 EEEEE 2135
Score = 65.5 bits (158), Expect = 2e-10
Identities = 76/275 (27%), Positives = 116/275 (42%), Gaps = 20/275 (7%)
Query: 371 ASARRRSSSSSSSSSAS-----RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRS 425
+S R+S SSS + + S+ + +G + RSRS+ S
Sbjct: 1773 SSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS 1832
Query: 426 RSRSR-RYSRSRSRGRRHSGGG-SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGG 483
+SR R S SRSR R+ S S SRS +RR R RS+SR +
Sbjct: 1833 EHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRK 1892
Query: 484 RGLRHHSSSRSR------SSWSLSPSRSRSLT---RSRSHSPSPSQSRSRSRSRSQSPSP 534
R +H S SR R S + R+RS T RSRSH+PS + RSRS R +S S
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-RRRRSRSVGRRRSFSI 1951
Query: 535 SPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADK 594
SP+R T P+ + +T P+ T + + + TP + + ++ +R +
Sbjct: 1952 SPSRRSRT-PSRRSRTPSRRSRT-PSRRSRTPSRRSR-TPSRRSRTPSRRRRSRSVVRRR 2008
Query: 595 KAAQEKMIQQEHERQEREDELRAMARKIRMKERER 629
+ + + R R+ R+ R + ER
Sbjct: 2009 SFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSER 2043
Score = 57.0 bits (136), Expect = 6e-08
Identities = 74/299 (24%), Positives = 107/299 (35%), Gaps = 53/299 (17%)
Query: 384 SSASRTSSSRSSSRSSSRSRRGGGY-----YRSGRHARSRSRSWSRSRSRSRRYSRSRSR 438
S+AS SS S S S Y + ++++ + +R S RSR
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 439 GRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSW 498
+R + R S S +R +R S+S+SH R R S R RSS
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSR----ARKRSSKSKSH------RSQTRSRSRSRRRRRSSR 1875
Query: 499 SLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTE 558
S S SR R SP + RS+SR + S +R+ +KT
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSP---KHRSKSRERKRKRSSSRDN--------------RKTV 1918
Query: 559 PAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAM 618
A + TP + + + + + R+ R R+
Sbjct: 1919 RARSRTPSRRSRSHTPSRR-------------RRSRSVGRRRSFSISPSRRSRTPSRRSR 1965
Query: 619 ARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRS-------RSRSP 670
R + RR + R SR+SR+PS R R S RRRS S RSR+P
Sbjct: 1966 TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS-RRRRSRSVVRRRSFSISPVRLRRSRTP 2023
Score = 37.4 bits (85), Expect = 0.046
Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 562 GKETGAAKPKLT--PQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMA 619
G++ AA P ++ P+ + ++ + + K EK ++ R + E E +
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKS-KKNKNRDKGEKEKK--- 1817
Query: 620 RKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
R ++ R +R K E R+ + +SRS + + S + S R ++RSRSRS R
Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Score = 37.0 bits (84), Expect = 0.059
Identities = 41/201 (20%), Positives = 77/201 (38%), Gaps = 27/201 (13%)
Query: 500 LSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQ-----SPSPSPAREKLTRPAASPAVGEKL 554
L P LT R+ P + R RS S P A E + + K+
Sbjct: 1737 LLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKV 1796
Query: 555 KKTEPAAGKETGAAKPKLTPQE--KLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612
K T + K K + + L+ R +++ + + K+ K+ ++ + ++ + +
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 613 DELRAMAR-KIRMKERERREKEREEWERQYSRQSRSPSPRY-SREYSSSRRRS------- 663
+ +R + R + R R + + R S++ R SP++ S+ R+RS
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916
Query: 664 -----------RSRSRSPHYR 673
RSRS +P R
Sbjct: 1917 TVRARSRTPSRRSRSHTPSRR 1937
Score = 32.3 bits (72), Expect = 1.5
Identities = 22/94 (23%), Positives = 46/94 (48%), Gaps = 9/94 (9%)
Query: 559 PAAGKETG--AAKPKLTPQEKLKLRMQKALNR------QFKADKKAAQEKMIQQEHERQE 610
P G + G AA + P E++ ++++ L+ ++K D K K + + +
Sbjct: 40 PIEGNQAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKS-RCVSVQTD 98
Query: 611 REDELRAMARKIRMKERERREKEREEWERQYSRQ 644
DE+ K K + +++K+++E E++Y RQ
Sbjct: 99 PTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQ 132
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 82.0 bits (201), Expect = 2e-15
Identities = 68/128 (53%), Positives = 73/128 (57%), Gaps = 15/128 (11%)
Query: 409 YRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGH-RYSRS-PARRGGYGPR 466
+R R RSRSRS S SRSR RRYSRSRSR R G SR R SRS RR
Sbjct: 120 HRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSR---GRRSRSASPRRSRSISLRRSRSASL 176
Query: 467 RRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSR 526
RRSRS S G RY S SRSRS S S SR RS +RS+S SPSP +SRS S
Sbjct: 177 RRSRSGSIKGSRY--------FQSPSRSRSR-SRSISRPRS-SRSKSRSPSPKRSRSPSG 226
Query: 527 SRSQSPSP 534
S +S SP
Sbjct: 227 SPRRSASP 234
Score = 53.1 bits (126), Expect = 8e-07
Identities = 45/94 (47%), Positives = 51/94 (54%), Gaps = 7/94 (7%)
Query: 369 RNASARRRSSSSSSSSSAS---RTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRS 425
R+ S RRS S+S S S R S S S RS S S +G Y++S +RSRSRS SR
Sbjct: 147 RSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRP 206
Query: 426 RSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR 459
RS SR SRS S R S GS R S SP R
Sbjct: 207 RS-SRSKSRSPSPKRSRSPSGS---PRRSASPER 236
Score = 43.5 bits (101), Expect = 6e-04
Identities = 61/232 (26%), Positives = 80/232 (34%), Gaps = 70/232 (30%)
Query: 437 SRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRS 496
SR R G R+ R PARR + P R Y G +G H++ R
Sbjct: 75 SRVRVELSTGMPRRSRFDRPPARRP-FDPNDRC---------YECGEKG--HYAYDCHRY 122
Query: 497 SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKK 556
S R RS +RSRSHS S + SRSRSRS+
Sbjct: 123 S-----RRRRSRSRSRSHSRSRGRRYSRSRSRSR-------------------------- 151
Query: 557 TEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELR 616
G+ + +A P+ + L+ +L R K
Sbjct: 152 -----GRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKG-------------------- 186
Query: 617 AMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
+R + R R R +SRSPSP+ SR S S RRS S R
Sbjct: 187 --SRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPER 236
Score = 33.5 bits (75), Expect = 0.66
Identities = 22/59 (37%), Positives = 25/59 (42%)
Query: 611 REDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
R R + R R R + R R+SRS SPR SR S R RS S RS
Sbjct: 121 RYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRS 179
Score = 31.6 bits (70), Expect = 2.5
Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 14/103 (13%)
Query: 234 DFVRMLRKDKEEAEAIKHAKA----LEEEKAMYSGRRSRRQR-REFREKRLRGRKISPPS 288
D R R+ + + + H+++ ++ GRRSR R R LR + +
Sbjct: 118 DCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLR 177
Query: 289 YARRDSPTYDPYKRSPSESSS---------ESRSRSRSPTPGR 322
+R S Y +SPS S S SRS+SRSP+P R
Sbjct: 178 RSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKR 220
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 81.3 bits (199), Expect = 3e-15
Identities = 101/378 (26%), Positives = 151/378 (39%), Gaps = 54/378 (14%)
Query: 301 KRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPP 360
+RSPS + + + + + P P R++ S E + A A+ ++G PAPP
Sbjct: 496 QRSPSPAPAPAPAAAAGP-PTRKK----------SRRERKRSGEAKEAASSSSGTQPAPP 544
Query: 361 QPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSR-----SRRGGGYYRS---- 411
P P + +R R S +SSSA R S SRS SRS+ R RR GG RS
Sbjct: 545 APASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSRE 604
Query: 412 GRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPA-RRGGYGPRRRSR 470
R R RS S + S S R R RG+ GGGS+ + SRS +R G G +
Sbjct: 605 KRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPA 664
Query: 471 SRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQ 530
G R R + P + LT + + + R +S
Sbjct: 665 PAPPPSGSTSCGDRDSRRRGA---------VPPSIQDLTDHDLFAIKRTITVGR-LDKSD 714
Query: 531 SPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQF 590
PSPA PA+SP E L +E +G+E G K + +++ R A +
Sbjct: 715 PRGPSPA------PASSPK-REVLYDSEGLSGEERGG---KSSQKDR---RRSGAASSSS 761
Query: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSP 650
+ +K ++ K + ++R+ R ++R+R K+ + P P
Sbjct: 762 SSREKGSRRKALDGGDRDRDRD----------RDRDRDRSSKKARPPKESAPSSGPPPKP 811
Query: 651 RYSREYSSSRRRSRSRSR 668
S SS S SR
Sbjct: 812 PVSSGSGSSSSSSSCSSR 829
Score = 50.8 bits (120), Expect = 4e-06
Identities = 89/360 (24%), Positives = 119/360 (33%), Gaps = 39/360 (10%)
Query: 260 AMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPT 319
A S RR R R R R R R S RR + +RS S R RS SP
Sbjct: 566 ASSSARRRSRSRSRSRSTRRRSR-----STDRRRGGS----RRSRSREKRRRRRRSASPP 616
Query: 320 PG--------REEKITFITSFGGSDEE---AAAAAAAAAASGVTTGKPPAPPQPGGPAPG 368
P RE GGS ++ + + + G PAPP G + G
Sbjct: 617 PATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCG 676
Query: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSW---SRS 425
S RR + S + + + R + S A S R S
Sbjct: 677 DRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEG 736
Query: 426 RSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRG-GYGPRRRSRSRSHSGDRYRRGGR 484
S R +S + RR SG S + R+ G R R R R DR
Sbjct: 737 LSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDR------ 790
Query: 485 GLRHHSSSRSRSSWSLSPSRS---RSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKL 541
SS ++R +PS + S S S S S S S + + QS RE +
Sbjct: 791 -----SSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGV 845
Query: 542 TRPA-ASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEK 600
+ A A L ++ + P L P E+ M KA K K + K
Sbjct: 846 SSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAK 905
Score = 49.3 bits (116), Expect = 1e-05
Identities = 38/150 (25%), Positives = 59/150 (39%), Gaps = 4/150 (2%)
Query: 519 SQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKL 578
+Q R R R RS SP+P+PA AA P +K ++ +G+ AA Q
Sbjct: 488 TQRRERYRQRSPSPAPAPA----PAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAP 543
Query: 579 KLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWE 638
+++ ++ + R R+ R+ R +R R R
Sbjct: 544 PAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSR 603
Query: 639 RQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
+ R+ RS SP + SSS RR R R +
Sbjct: 604 EKRRRRRRSASPPPATSSSSSSRRERHRGK 633
Score = 43.5 bits (101), Expect = 6e-04
Identities = 45/194 (23%), Positives = 77/194 (39%), Gaps = 25/194 (12%)
Query: 240 RKDKEEAEAIKHAKALEEE----KAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSP 295
+KD+ + A + + E+ KA+ G R R + R+ R++ +K PP + +P
Sbjct: 748 QKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRD-RDRDRSSKKARPP---KESAP 803
Query: 296 TYDPYKRSPSESSSESRSRSRSPTPGR---EEKITFITSFGGSDEEAAAAAAAAAASGVT 352
+ P + P S S S S S S + + + K+ + G S A AA+A +
Sbjct: 804 SSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIG 863
Query: 353 TG------------KPP--APPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRS 398
KP AP + APG + + + + + T S++
Sbjct: 864 VKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKT 923
Query: 399 SSRSRRGGGYYRSG 412
+ R GGG SG
Sbjct: 924 RKKVRSGGGSGGSG 937
Score = 33.1 bits (74), Expect = 0.86
Identities = 31/104 (29%), Positives = 39/104 (37%), Gaps = 11/104 (10%)
Query: 511 SRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKP 570
S S SPSPS S S SPSP P P A PA A P
Sbjct: 192 SASSSPSPSPS-------SSSPSPPPP----PPPPAPPAPPAPRFDIYDPFHPTDEAYSP 240
Query: 571 KLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDE 614
P++K N A + +E+ ++E E +E EDE
Sbjct: 241 PPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDE 284
Score = 30.4 bits (67), Expect = 5.6
Identities = 44/198 (22%), Positives = 69/198 (34%), Gaps = 34/198 (17%)
Query: 479 YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS-----RSQSPS 533
+R GGR R P+ + S T + P P R+ ++S
Sbjct: 410 FRPGGRAAR--------------PTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDG 455
Query: 534 PSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAA--KPKLTPQEKLKLRMQKALNRQFK 591
+ L PA +P PAA G + K+ Q + + R +
Sbjct: 456 EGALQVDLGEPAPAP----------PAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAP 505
Query: 592 ADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPR 651
A AA ++ ++R E + A + +++ + R P
Sbjct: 506 APAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSH 565
Query: 652 YSREYSSSRRRSRSRSRS 669
S SS+RRRSRSRSRS
Sbjct: 566 AS---SSARRRSRSRSRS 580
Score = 29.6 bits (65), Expect = 9.5
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
Query: 312 RSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAAS----GVTTGKPPAPPQPGGPAP 367
+S S PT R +T T GG A ++A+++ S + PP PP P PAP
Sbjct: 163 QSNSSRPTCARH--LTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAP 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.123 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,454,085
Number of Sequences: 37866
Number of extensions: 1604440
Number of successful extensions: 54932
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 875
Number of HSP's successfully gapped in prelim test: 1697
Number of HSP's that attempted gapping in prelim test: 19606
Number of HSP's gapped (non-prelim): 16834
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.