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Search of human proteins with 133908641
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|133908641 myosin binding protein C, fast type [Homo sapiens]
(1141 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 2298 0.0
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 1229 0.0
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ... 1168 0.0
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ... 1164 0.0
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ... 1164 0.0
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ... 1158 0.0
gi|55956914 myosin binding protein H [Homo sapiens] 457 e-128
gi|194018539 myosin binding protein H-like [Homo sapiens] 342 2e-93
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] 310 7e-84
gi|110349719 titin isoform N2-A [Homo sapiens] 275 1e-73
gi|110349717 titin isoform novex-2 [Homo sapiens] 275 1e-73
gi|110349713 titin isoform novex-1 [Homo sapiens] 275 1e-73
gi|110349715 titin isoform N2-B [Homo sapiens] 275 1e-73
gi|148839296 immunoglobulin-like and fibronectin type III domain... 266 8e-71
gi|156104903 myomesin 2 [Homo sapiens] 132 1e-30
gi|140560917 myomesin 1 isoform b [Homo sapiens] 127 6e-29
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 125 2e-28
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 125 2e-28
gi|144226847 obscurin-like 1 [Homo sapiens] 125 3e-28
gi|110349721 titin isoform novex-3 [Homo sapiens] 124 5e-28
gi|155969693 myomesin family, member 3 [Homo sapiens] 112 3e-24
gi|140560919 myomesin 1 isoform a [Homo sapiens] 110 8e-24
gi|19743806 roundabout 1 isoform b [Homo sapiens] 102 2e-21
gi|4506569 roundabout 1 isoform a [Homo sapiens] 102 2e-21
gi|119220552 sidekick 1 [Homo sapiens] 102 3e-21
gi|224994173 roundabout 1 isoform d [Homo sapiens] 100 8e-21
gi|224994171 roundabout 1 isoform c [Homo sapiens] 100 8e-21
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 100 8e-21
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 100 8e-21
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 99 2e-20
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 2298 bits (5956), Expect = 0.0
Identities = 1141/1141 (100%), Positives = 1141/1141 (100%)
Query: 1 MPEAKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDS 60
MPEAKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDS
Sbjct: 1 MPEAKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDS 60
Query: 61 VSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVE 120
VSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVE
Sbjct: 61 VSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVE 120
Query: 121 LHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKSDTAG 180
LHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKSDTAG
Sbjct: 121 LHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKSDTAG 180
Query: 181 ELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRG 240
ELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRG
Sbjct: 181 ELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRG 240
Query: 241 MLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSS 300
MLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSS
Sbjct: 241 MLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSS 300
Query: 301 KYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVG 360
KYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVG
Sbjct: 301 KYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVG 360
Query: 361 DRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ 420
DRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ
Sbjct: 361 DRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ 420
Query: 421 VITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRP 480
VITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRP
Sbjct: 421 VITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRP 480
Query: 481 SKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPK 540
SKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPK
Sbjct: 481 SKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPK 540
Query: 541 IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDC 600
IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDC
Sbjct: 541 IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDC 600
Query: 601 SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWE 660
SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWE
Sbjct: 601 SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWE 660
Query: 661 PPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG 720
PPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG
Sbjct: 661 PPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG 720
Query: 721 VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGS 780
VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGS
Sbjct: 721 VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGS 780
Query: 781 EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKI 840
EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKI
Sbjct: 781 EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKI 840
Query: 841 RLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVR 900
RLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVR
Sbjct: 841 RLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVR 900
Query: 901 QAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDG 960
QAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDG
Sbjct: 901 QAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDG 960
Query: 961 NSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGV 1020
NSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGV
Sbjct: 961 NSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGV 1020
Query: 1021 SKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVV 1080
SKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVV
Sbjct: 1021 SKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVV 1080
Query: 1081 WMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
WMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP
Sbjct: 1081 WMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
Query: 1141 Q 1141
Q
Sbjct: 1141 Q 1141
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 1229 bits (3179), Expect = 0.0
Identities = 632/1190 (53%), Positives = 804/1190 (67%), Gaps = 65/1190 (5%)
Query: 3 EAKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTA-----------EEPT 51
+A+P AP +A GAP EAP APA E+ P + ++ ++P
Sbjct: 99 KAEPMLAPAPAPAEAT-GAPGEAP---APAAELGESAPSPKGSSSAALNGPTPGAPDDPI 154
Query: 52 GVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHN 111
G+F+ +P V G A+V G L P +KWFKGKW++L SK G +S++
Sbjct: 155 GLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYD 214
Query: 112 SASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRT 171
AS VY ELHI G YR EV KD D FN+ V L +F+RT
Sbjct: 215 RASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRT 274
Query: 172 S---------EKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPE--IWELLKG 220
S + DT G LDFS LLKKR+ + D L P E +WE+L+
Sbjct: 275 SLAGGGRRISDSHEDT-GILDFSSLLKKRDSFRTPR------DSKLEAPAEEDVWEILRQ 327
Query: 221 AKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEI 280
A SEYE+IAFQYG+TDLRGMLKRLK + + KKS AF KKL+PAYQV +G+KI+L VE+
Sbjct: 328 APPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVEL 387
Query: 281 SDPDLTLKWFKNGQEIKPS-SKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTEL 339
+D D +KW KNGQEI+ S SKY+FE++G KR LTI++C+LADDAAY+ V EKC TEL
Sbjct: 388 ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTEL 447
Query: 340 FVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKK 399
FVKEPPVLI PLEDQ V VG RVE EVSEEGAQV W+KDGVELTRE++FK YRFKK
Sbjct: 448 FVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFK--YRFKK 505
Query: 400 DGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFK 459
DG+RH LI ++ + ED G Y + T+GGQ AELIV+EK+LEV Q IADL V A +QAVFK
Sbjct: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFK 565
Query: 460 CEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSL 519
CEVSDE V G W KNG E+ P RI +SH+GR HKL IDDV P DE DY+FVP+G+A +L
Sbjct: 566 CEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
Query: 520 SAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWL 579
SAKL+F+E+K+++VP+QEPPKIHLDC G+ + IVVVAGNKLRLDV I+G+P P W
Sbjct: 626 SAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDT-IVVVAGNKLRLDVPISGDPAPTVIWQ 684
Query: 580 K--------------------GD--------EVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
K GD ++ TEGR R+E D S F +E A++E
Sbjct: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
DEG YT+ V NPVGED ++ ++V+DVPD P A +I++VGED + WEPP YDGG+P+
Sbjct: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
Query: 672 GYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPF 731
GY++ERKKK S RWM+LNF++ E ++E+ +MIEG++YEMRV+AVNAIG+S+PS ++PF
Sbjct: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF 864
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
MPI P SEP HL VEDV+DTT +LKWRPP R+GAGG+DGY VEYC EG EWV A
Sbjct: 865 MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
E VK+LPTGAR+LFRV N+AG P T +PVT++EI + P+++LPRHLRQT
Sbjct: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
+KVGE +NL++PFQGKPRPQV WTK G PL V +R S DT+ F+R A R SG Y+
Sbjct: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
++V+IENM+D AT+ ++VV+K PP ++ V + WG N +EW+ P+D GN+E+ GY VQK
Sbjct: 1045 VTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
ADKKTMEWF V E R T C V +LI+GN YYFRV+++N+ G SD +K I + G
Sbjct: 1105 ADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPG 1164
Query: 1032 ITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED 1091
IT++P YK DF AP F PL++R V+AGY+A L CAVRG PKPK+ W KN +++ ED
Sbjct: 1165 ITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGED 1224
Query: 1092 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+F + + QGVLTL IR+P PFD G Y CRA N GEA EC+LEVRVPQ
Sbjct: 1225 ARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 450 VKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
V A AVF+ E V +W + G ++ S + ++ G H L + +V P D+G Y
Sbjct: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
Query: 510 FVPDGYALSLSAKLNFLEIKVEYVPKQEP 538
+ S+K+ F ++KV K EP
Sbjct: 81 VIAG------SSKVKF-DLKVIEAEKAEP 102
Score = 38.9 bits (89), Expect = 0.028
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 253 KKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRI 312
K +AF+KK + +V G+ E + ++W + G +I S+KY G +
Sbjct: 7 KPVSAFSKK-PRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
Query: 313 LTINKCTLADDAAYEVAVKDEKCFTELFV----KEPPVLIVTP 351
LT+ + AD +Y V K +L V K P+L P
Sbjct: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAP 108
Score = 37.7 bits (86), Expect = 0.063
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 356 QVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQED 415
+V G E G +V W + G +++ + +Y +G RH L +V D
Sbjct: 20 EVAAGSPAVFEAETERAGVKVRWQRGGSDISASN----KYGLATEGTRHTLTVREVGPAD 75
Query: 416 RGRYQVITNGGQCEAELIVEEKQ 438
+G Y VI + + +L V E +
Sbjct: 76 QGSYAVIAGSSKVKFDLKVIEAE 98
>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
sapiens]
Length = 1123
Score = 1168 bits (3022), Expect = 0.0
Identities = 571/1135 (50%), Positives = 782/1135 (68%), Gaps = 44/1135 (3%)
Query: 22 PKEAPPKEAPAEAPKEA---PPED----QSPTAEEPTG---------VFLKKPDSVSVET 65
P APP E P++ KEA P +D ++P EE +F++KP +V+
Sbjct: 13 PAPAPPPEEPSKE-KEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKV 71
Query: 66 GKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGK 125
G+D +AKV ++L KPTIKWFKGKW++L SK+G KE+ S VYT E+ I K
Sbjct: 72 GEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIK 131
Query: 126 VVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLES-FKRTSEKKSDTAGELDF 184
G YR EV KD DSC F+++V + S FKR+ E + D AGELDF
Sbjct: 132 AKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQED-AGELDF 190
Query: 185 SGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKR 244
SGLLK+REV ++E++ + ++WELLK AK SEYEKIAFQYGITDLRGMLKR
Sbjct: 191 SGLLKRREVKQQEEEPQV----------DVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 240
Query: 245 LKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVF 304
LK+ + E KKSAAF K LDPAYQVD+G +++ +VE++DP L +KW+KNGQEI+PS+KY+F
Sbjct: 241 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
Query: 305 ENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVE 364
E+ G +RIL IN C + DD+ Y V DEKC TELFV+EPP+++ LED + G+RVE
Sbjct: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
Query: 365 MAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITN 424
+ EVSE+ A V W K+G E+ K+RYR + +GK+HILI + D Y V+T
Sbjct: 361 LECEVSEDDANVKWFKNGEEIIPGP--KSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
Query: 425 GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRI 484
GGQ A+L V+ K L++L + D TV ++ KCE+S E + GKW KNG+ V+ S R+
Sbjct: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 477
Query: 485 TISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLD 544
+ H GR HKLVI + EDEGDY F PD Y ++L AK++ ++ PPKI LD
Sbjct: 478 KVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVID----------PPKIILD 527
Query: 545 CSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 604
G ++N + V+AGNKLRL++ I+GEPPP A W +GD+ GR R E D S+ V
Sbjct: 528 --GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLV 585
Query: 605 IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMY 664
I+ A+R+D G Y I + N GE ASI ++VVD PDPP A +T VG+DW I+ WEPP Y
Sbjct: 586 IDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAY 645
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
DGG P+ GY +ERKKK S RWM+LNF++ ETT+E KMIEG+ YE+R+FAVNAIG+S+P
Sbjct: 646 DGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKP 705
Query: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
SM ++PF+P+A TS P L V+ VTDTT T++WRPP+ IGA G+DGY++EYC EG+E+W+
Sbjct: 706 SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 765
Query: 785 PANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
AN + +++ FT+ LPT A+I RV VN AG SEP +QP+ ++EI EPPKIR+PR
Sbjct: 766 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 825
Query: 845 HLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAAR 904
HL+QTYIR+VGE +NLV+PFQGKPRP++ W K GA +D +++++R S+ DT+ F+R+A R
Sbjct: 826 HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 885
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEI 964
S SG+Y+L V+++ +TA+I I+++++ GPP V +++VWG N + W PKDDGN+ I
Sbjct: 886 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 945
Query: 965 MGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNT 1024
GY +QKADKK+MEWF V E TS T+++L++GNEYYFRV++EN+CGLS+ ++K +
Sbjct: 946 TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKES 1005
Query: 1025 ARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKN 1084
A I + G +K Y++ DF AP F PL++ +AGY+A LNC+VRG+PKPK+ WMKN
Sbjct: 1006 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1065
Query: 1085 KMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
K+ I +DP++ + + QGV TL IR+PSP+D GTY C+AVN+LG ECKLEV+V
Sbjct: 1066 KVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1120
>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
sapiens]
Length = 1148
Score = 1164 bits (3010), Expect = 0.0
Identities = 573/1171 (48%), Positives = 783/1171 (66%), Gaps = 58/1171 (4%)
Query: 1 MPE-AKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSP-------------- 45
MPE K + P P+ KE PA+ +E P P
Sbjct: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
Query: 46 --TAEEPTG--------------VFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWF 89
E P G +F++KP +V+ G+D +AKV ++L KPTIKWF
Sbjct: 61 WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
Query: 90 KGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGF 149
KGKW++L SK+G KE+ S VYT E+ I K G YR EV KD DSC F
Sbjct: 121 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
Query: 150 NIDVEAPRQDASGQSLES-FKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDL 208
+++V + S FKR+ E + D AGELDFSGLLK+REV ++E++ +
Sbjct: 181 DLEVHESTGTTPNIDIRSAFKRSGEGQED-AGELDFSGLLKRREVKQQEEEPQ------- 232
Query: 209 GIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQV 268
++WELLK AK SEYEKIAFQYGITDLRGMLKRLK+ + E KKSAAF K LDPAYQV
Sbjct: 233 ---VDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQV 289
Query: 269 DRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV 328
D+G +++ +VE++DP L +KW+KNGQEI+PS+KY+FE+ G +RIL IN C + DD+ Y V
Sbjct: 290 DKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV 349
Query: 329 AVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTRE 388
DEKC TELFV+EPP+++ LED + G+RVE+ EVSE+ A V W K+G E+
Sbjct: 350 TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII-- 407
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADL 448
K+RYR + +GK+HILI + D Y V+T GGQ A+L V+ K L++L + D
Sbjct: 408 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
Query: 449 TVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
TV ++ KCE+S E + GKW KNG+ V+ S R+ + H GR HKLVI + EDEGDY
Sbjct: 468 TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
F PD Y ++L AK++ + +PPKI LD G ++N + V+AGNKLRL++ I
Sbjct: 527 VFAPDAYNVTLPAKVHVI----------DPPKIILD--GLDADNTVTVIAGNKLRLEIPI 574
Query: 569 TGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 628
+GEPPP A W +GD+ GR R E D S+ VI+ A+R+D G Y I + N GE
Sbjct: 575 SGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAH 634
Query: 629 ASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKL 688
ASI ++VVD PDPP A +T VG+DW I+ WEPP YDGG P+ GY +ERKKK S RWM+L
Sbjct: 635 ASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRL 694
Query: 689 NFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDV 748
NF++ ETT+E KMIEG+ YE+R+FAVNAIG+S+PSM ++PF+P+A TS P L V+ V
Sbjct: 695 NFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSV 754
Query: 749 TDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARIL 808
TDTT T++WRPP+ IGA G+DGY++EYC EG+E+W+ AN + +++ FT+ LPT A+I
Sbjct: 755 TDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIF 814
Query: 809 FRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP 868
RV VN AG SEP +QP+ ++EI EPPKIR+PRHL+QTYIR+VGE +NLV+PFQGKP
Sbjct: 815 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
Query: 869 RPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
RP++ W K GA +D +++++R S+ DT+ F+R+A RS SG+Y+L V+++ +TA+I I+
Sbjct: 875 RPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 934
Query: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
++++ GPP V +++VWG N + W PKDDGN+ I GY +QKADKK+MEWF V E
Sbjct: 935 IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
Query: 989 TSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAP 1048
TS T+++L++GNEYYFRV++EN+CGLS+ ++K +A I + G +K Y++ DF AP
Sbjct: 995 TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
F PL++ +AGY+A LNC+VRG+PKPK+ WMKNK+ I +DP++ + + QGV TL IR
Sbjct: 1055 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1114
Query: 1109 RPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
+PSP+D GTY C+AVN+LG ECKLEV+V
Sbjct: 1115 KPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
sapiens]
Length = 1171
Score = 1164 bits (3010), Expect = 0.0
Identities = 573/1171 (48%), Positives = 783/1171 (66%), Gaps = 58/1171 (4%)
Query: 1 MPE-AKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSP-------------- 45
MPE K + P P+ KE PA+ +E P P
Sbjct: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
Query: 46 --TAEEPTG--------------VFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWF 89
E P G +F++KP +V+ G+D +AKV ++L KPTIKWF
Sbjct: 61 WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
Query: 90 KGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGF 149
KGKW++L SK+G KE+ S VYT E+ I K G YR EV KD DSC F
Sbjct: 121 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
Query: 150 NIDVEAPRQDASGQSLES-FKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDL 208
+++V + S FKR+ E + D AGELDFSGLLK+REV ++E++ +
Sbjct: 181 DLEVHESTGTTPNIDIRSAFKRSGEGQED-AGELDFSGLLKRREVKQQEEEPQ------- 232
Query: 209 GIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQV 268
++WELLK AK SEYEKIAFQYGITDLRGMLKRLK+ + E KKSAAF K LDPAYQV
Sbjct: 233 ---VDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQV 289
Query: 269 DRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV 328
D+G +++ +VE++DP L +KW+KNGQEI+PS+KY+FE+ G +RIL IN C + DD+ Y V
Sbjct: 290 DKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV 349
Query: 329 AVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTRE 388
DEKC TELFV+EPP+++ LED + G+RVE+ EVSE+ A V W K+G E+
Sbjct: 350 TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII-- 407
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADL 448
K+RYR + +GK+HILI + D Y V+T GGQ A+L V+ K L++L + D
Sbjct: 408 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
Query: 449 TVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
TV ++ KCE+S E + GKW KNG+ V+ S R+ + H GR HKLVI + EDEGDY
Sbjct: 468 TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
F PD Y ++L AK++ + +PPKI LD G ++N + V+AGNKLRL++ I
Sbjct: 527 VFAPDAYNVTLPAKVHVI----------DPPKIILD--GLDADNTVTVIAGNKLRLEIPI 574
Query: 569 TGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 628
+GEPPP A W +GD+ GR R E D S+ VI+ A+R+D G Y I + N GE
Sbjct: 575 SGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAH 634
Query: 629 ASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKL 688
ASI ++VVD PDPP A +T VG+DW I+ WEPP YDGG P+ GY +ERKKK S RWM+L
Sbjct: 635 ASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRL 694
Query: 689 NFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDV 748
NF++ ETT+E KMIEG+ YE+R+FAVNAIG+S+PSM ++PF+P+A TS P L V+ V
Sbjct: 695 NFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSV 754
Query: 749 TDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARIL 808
TDTT T++WRPP+ IGA G+DGY++EYC EG+E+W+ AN + +++ FT+ LPT A+I
Sbjct: 755 TDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIF 814
Query: 809 FRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP 868
RV VN AG SEP +QP+ ++EI EPPKIR+PRHL+QTYIR+VGE +NLV+PFQGKP
Sbjct: 815 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
Query: 869 RPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
RP++ W K GA +D +++++R S+ DT+ F+R+A RS SG+Y+L V+++ +TA+I I+
Sbjct: 875 RPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 934
Query: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
++++ GPP V +++VWG N + W PKDDGN+ I GY +QKADKK+MEWF V E
Sbjct: 935 IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
Query: 989 TSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAP 1048
TS T+++L++GNEYYFRV++EN+CGLS+ ++K +A I + G +K Y++ DF AP
Sbjct: 995 TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
F PL++ +AGY+A LNC+VRG+PKPK+ WMKNK+ I +DP++ + + QGV TL IR
Sbjct: 1055 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1114
Query: 1109 RPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
+PSP+D GTY C+AVN+LG ECKLEV+V
Sbjct: 1115 KPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
sapiens]
Length = 1141
Score = 1158 bits (2996), Expect = 0.0
Identities = 572/1153 (49%), Positives = 782/1153 (67%), Gaps = 62/1153 (5%)
Query: 22 PKEAPPKEAPAEAPKEA---PPED----QSPTAEEPTG---------VFLKKPDSVSVET 65
P APP E P++ KEA P +D ++P EE +F++KP +V+
Sbjct: 13 PAPAPPPEEPSKE-KEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKV 71
Query: 66 GKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGK 125
G+D +AKV ++L KPTIKWFKGKW++L SK+G KE+ S VYT E+ I K
Sbjct: 72 GEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIK 131
Query: 126 VVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLES-FKRTSEKKSDTAGELDF 184
G YR EV KD DSC F+++V + S FKR+ E + D AGELDF
Sbjct: 132 AKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQED-AGELDF 190
Query: 185 SGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKR 244
SGLLK+REV ++E++ + ++WELLK AK SEYEKIAFQYGITDLRGMLKR
Sbjct: 191 SGLLKRREVKQQEEEPQV----------DVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 240
Query: 245 LKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVF 304
LK+ + E KKSAAF K LDPAYQVD+G +++ +VE++DP L +KW+KNGQEI+PS+KY+F
Sbjct: 241 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
Query: 305 ENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVE 364
E+ G +RIL IN C + DD+ Y V DEKC TELFV+EPP+++ LED + G+RVE
Sbjct: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
Query: 365 MAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITN 424
+ EVSE+ A V W K+G E+ K+RYR + +GK+HILI + D Y V+T
Sbjct: 361 LECEVSEDDANVKWFKNGEEIIPGP--KSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
Query: 425 GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRI 484
GGQ A+L V+ K L++L + D TV ++ KCE+S E + GKW KNG+ V+ S R+
Sbjct: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 477
Query: 485 TISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLD 544
+ H GR HKLVI + EDEGDY F PD Y ++L AK++ ++ PPKI LD
Sbjct: 478 KVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVID----------PPKIILD 527
Query: 545 CSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 604
G ++N + V+AGNKLRL++ I+GEPPP A W +GD+ GR R E D S+ V
Sbjct: 528 --GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLV 585
Query: 605 IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMY 664
I+ A+R+D G Y I + N GE ASI ++VVD PDPP A +T VG+DW I+ WEPP Y
Sbjct: 586 IDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAY 645
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
DGG P+ GY +ERKKK S RWM+LNF++ ETT+E KMIEG+ YE+R+FAVNAIG+S+P
Sbjct: 646 DGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKP 705
Query: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGS---- 780
SM ++PF+P+A TS P L V+ VTDTT T++WRPP+ IGA G+DGY++EYC EGS
Sbjct: 706 SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
Query: 781 --------------EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA 826
E+W+ AN + +++ FT+ LPT A+I RV VN AG SEP +
Sbjct: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
Query: 827 QPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRV 886
QP+ ++EI EPPKIR+PRHL+QTYIR+VGE +NLV+PFQGKPRP++ W K GA +D +++
Sbjct: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQI 885
Query: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWG 946
++R S+ DT+ F+R+A RS SG+Y+L V+++ +TA+I I+++++ GPP V +++VWG
Sbjct: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWG 945
Query: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRV 1006
N + W PKDDGN+ I GY +QKADKK+MEWF V E TS T+++L++GNEYYFRV
Sbjct: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
Query: 1007 YTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAA 1066
++EN+CGLS+ ++K +A I + G +K Y++ DF AP F PL++ +AGY+A
Sbjct: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
Query: 1067 LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNEL 1126
LNC+VRG+PKPK+ WMKNK+ I +DP++ + + QGV TL IR+PSP+D GTY C+AVN+L
Sbjct: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
Query: 1127 GEALAECKLEVRV 1139
G ECKLEV+V
Sbjct: 1126 GTVEIECKLEVKV 1138
>gi|55956914 myosin binding protein H [Homo sapiens]
Length = 477
Score = 457 bits (1175), Expect = e-128
Identities = 219/415 (52%), Positives = 286/415 (68%), Gaps = 1/415 (0%)
Query: 725 SMNTKPFMPIAPT-SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW 783
S TKP P S PL L ++DV+ ++ T+ W PP R+G G+ GY++E C EG+ EW
Sbjct: 58 STATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEW 117
Query: 784 VPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLP 843
VP + P+ TV+NL G + L RV V+ AG PA L QP+ IRE E PKIR+P
Sbjct: 118 VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVP 177
Query: 844 RHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAA 903
RHLRQTYIR+VGE +NL +PFQGKP+PQ WT G LD+ RV +RT D D++ F+R A
Sbjct: 178 RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQ 237
Query: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
RSDSG YEL+V++E+++ A I I V+EK GPP ++ + +VWG NA ++W P+D GN+E
Sbjct: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
Query: 964 IMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKN 1023
++GY VQKADKKT +WF V ER T+CT+SDLI+GN Y FRV++EN+CGLS S V+K
Sbjct: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
Query: 1024 TARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMK 1083
A I K I KP + E DF AP F PL D GYS L C+VR PKPK++WMK
Sbjct: 358 LAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK 417
Query: 1084 NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
NKMEI+ +PK+ + QGV TL IR+PSPFD+G YTC+A+N LGEA +C+LEV+
Sbjct: 418 NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
Score = 84.0 bits (206), Expect = 8e-16
Identities = 58/193 (30%), Positives = 86/193 (44%), Gaps = 6/193 (3%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
E PKI + + + G + L + G+P P ATW + R +
Sbjct: 170 EAPKIRVP---RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ--RVSMRT 224
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
S I SAQR D GRY + V E A I + V++ P PP ++R+ V A
Sbjct: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W PP G + GY+V++ K + +W + E + TT + +I G Y RVF+
Sbjct: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSE 343
Query: 717 NAIGVSQPSMNTK 729
N G+S + TK
Sbjct: 344 NLCGLSTSATVTK 356
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/94 (26%), Positives = 44/94 (46%)
Query: 637 DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTET 696
DVP P + + V + WEPP G + GY++E ++G+ W+ ++ T
Sbjct: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
+ G + +RV AV++ G P+M +P
Sbjct: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
>gi|194018539 myosin binding protein H-like [Homo sapiens]
Length = 354
Score = 342 bits (876), Expect = 2e-93
Identities = 157/313 (50%), Positives = 216/313 (69%)
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH 887
P + I E PKI LPR LRQTYIRKVG+ +NL++PFQGKP+PQ +WT G LDT RV
Sbjct: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVS 100
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGT 947
VR + D++ F+R+A R+DSG Y+L VQ+ ++ TATI I V+E+ GPP ++ + +VWG
Sbjct: 101 VRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGF 160
Query: 948 NALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVY 1007
+A +EW P+D GN+ ++GY VQKAD K+ WF V E TSC VSDLI+GN Y FRV+
Sbjct: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVF 220
Query: 1008 TENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAAL 1067
EN CGLS++ ++ + A I K +K + + DF APKF PL D V GY+ L
Sbjct: 221 AENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQL 280
Query: 1068 NCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
C VR P+PK++W+KNKM+I+ +PK+ + G+ +L IR+P PFD G YTC+AVN LG
Sbjct: 281 FCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
Query: 1128 EALAECKLEVRVP 1140
EA +C+++V+VP
Sbjct: 341 EASVDCRVDVKVP 353
Score = 79.7 bits (195), Expect = 1e-14
Identities = 56/190 (29%), Positives = 85/190 (44%), Gaps = 6/190 (3%)
Query: 534 PKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR 593
P +E PKI L + + G+ + L + G+P P A W T R
Sbjct: 46 PIEEHPKIWLP---RALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR--RVS 100
Query: 594 IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGED 653
+ S I AQR D GRY ++V E A+I + V++ P PP+++++ V
Sbjct: 101 VRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGF 160
Query: 654 WAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRV 713
A L W PP G + GY V++ S W + E + T+ + +I G Y RV
Sbjct: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRV 219
Query: 714 FAVNAIGVSQ 723
FA N G+S+
Sbjct: 220 FAENQCGLSE 229
Score = 44.7 bits (104), Expect = 5e-04
Identities = 41/152 (26%), Positives = 57/152 (37%), Gaps = 19/152 (12%)
Query: 740 PLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVK 799
P + + DV + TL+W PP G + GY V+ S W E R V
Sbjct: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVS 207
Query: 800 NLPTGARILFRVVGVNIAGRSEPATLA-------QPVTI--------REIAEPPKIRLPR 844
+L G FRV N G SE A + + T+ R+ +E PK P
Sbjct: 208 DLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPL 267
Query: 845 HLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
T G L + PRP+++W K
Sbjct: 268 ADCTTV---TGYNTQLFCCVRASPRPKIIWLK 296
>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
Length = 1326
Score = 310 bits (793), Expect = 7e-84
Identities = 254/903 (28%), Positives = 390/903 (43%), Gaps = 61/903 (6%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V ++ L E++ D+TL+W K+GQ + +KY + GK+ L I L+D Y
Sbjct: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
Query: 327 EVAVKDEKCFTELF------VKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMK 380
V + TE + V+E + + + D G E+ V +++E + +W+K
Sbjct: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
Query: 381 DGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQL- 439
DG E+T + K G H LIF + E G+Y G + EA + + +
Sbjct: 549 DGKEITDLPGMQ----IVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
Query: 440 --EVLQDIAD--LTVKASEQAVFKCEVSDE---KVTGKWYKNGVEVRPSKRITISHVGRF 492
VL+ +A +TVK A K + KVT WYK+G+EV +R+++
Sbjct: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT--WYKDGMEVTEEERVSMERGEDQ 662
Query: 493 HKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH---LDCSGKT 549
L I + ED G S +A L+ + + + +PP+ L+ SG
Sbjct: 663 ALLTISNCVREDSGLILLKLKNDHGSATATLH-----LSVLDRPKPPQGRVEFLELSGSC 717
Query: 550 SENAIVVVAGNKLRLDVSITGEPPPVA--TWLKGDEVFTTTEGRTRIEKRVDCSSFVIES 607
N R E V +W+K EV +G+ ++F
Sbjct: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEV----DGKV--------TNFSTNK 765
Query: 608 AQREDEGRYTIKVTNPVGE----DVASIFL-QVVDVPDPPEAVRITSVGEDWAILVWEPP 662
+ ++ I N G + +F ++ P ++T V ++ + W P
Sbjct: 766 VEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
Query: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
DGG PV GY+VER+KKGS W+ +N + T ++E YE RV AVN G
Sbjct: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
Query: 723 QPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEG 779
QPS+ + + P+ P L V D ++++ +L WR P GY++E E
Sbjct: 886 QPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAED 943
Query: 780 SEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK 839
++EW P+ +TV L + FR+ VN AG EP L + V PK
Sbjct: 944 TKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPK 1003
Query: 840 IRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFV 899
L L+ + + G L + F G P P V+W K G P R + S + F +
Sbjct: 1004 FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNHSQFLI 1062
Query: 900 RQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
RSDSG Y + +Q E + I +RV + PP N+ + E + W D
Sbjct: 1063 NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDV 1122
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
Y + K D T W+ ER TV+ L+ G +YYFRV N G S+ P
Sbjct: 1123 QEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE-PL 1181
Query: 1020 VSKNTARILKTGI-----TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGH 1074
S++T I K I KP+E K D+R AP+F+TPL V+ G + CA G+
Sbjct: 1182 DSRDTWLINKDQIQDLSAKLKPYEKK--DWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGN 1239
Query: 1075 PKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECK 1134
P+P V K + I + KF + GV TL I + D+G Y+ NELG+ + C
Sbjct: 1240 PRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
Query: 1135 LEV 1137
L V
Sbjct: 1300 LTV 1302
Score = 244 bits (624), Expect = 3e-64
Identities = 254/1000 (25%), Positives = 398/1000 (39%), Gaps = 131/1000 (13%)
Query: 54 FLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLE------------------ 95
F++KP V+ G AV A+V G KP I W + +
Sbjct: 69 FVEKPQPVTAPEGDKAVFRARVQGNA---KPHISWKRESGIPIKESAKIFYDSINKEHVL 125
Query: 96 ----LGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKA--KDTCDSCGF 149
L S + S++ A +YTV L L G +++ K K
Sbjct: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSL------LVTEGQEKMDFKKMLKKRAPPAPK 179
Query: 150 NIDVEAPRQDASGQSLESF-KRTSEKKSDTAGELDFSGLLKKREVVEEEKKK-------- 200
+ + + L K+ EK G DF GLL+K ++E KKK
Sbjct: 180 KKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRK---LKEMKKKVEVEAIRI 236
Query: 201 -KKKDDDDLGIPPE-----IWEL---------LKGAK---------KSEYEKIAFQY--- 233
K +D + + I EL +KG + K + +++ +Y
Sbjct: 237 LKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLV 296
Query: 234 ---------GITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPD 284
GI L KR+ + + F ++ P +R + + +S +
Sbjct: 297 ISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAV-FEIRLSKKE 355
Query: 285 LTLKWFKNGQEIKPSSKY--VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVK 342
W NG+E+K KY G L I L+D + + +L +
Sbjct: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
Query: 343 EPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGK 402
P+ V+ L++ +V R + E++ + + W KDG L +Y +GK
Sbjct: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHG----TKYSMNHEGK 471
Query: 403 RHILIFSDVVQEDRGRYQVIT--NGGQCE----AELIVEEKQLEVLQDIADLTVKASEQA 456
R LI D D G Y V+ +G E A + VEE+ V ++D+ A
Sbjct: 472 RAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPA 531
Query: 457 VFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYA 516
++DEKV G W K+G E+ + I G HKL+ + PE EG YTF G
Sbjct: 532 ELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTE 591
Query: 517 LSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVA 576
S + +PP I + +AI V G+ + V G+P P
Sbjct: 592 SEASVFI------------ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
Query: 577 TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVV 636
TW K D + T E R +E+ D + I + RED G +K+ N G A++ L V+
Sbjct: 640 TWYK-DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL 698
Query: 637 DVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
D P PP+ V + + W+ P +GG+PVT ++VER+ G + W+K+
Sbjct: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--PIAPTSEPLHLIVEDVTDTTT 753
T + + K+ EG Y+ R+ AVN+ GVS P + F PI P V DVT
Sbjct: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAV 818
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813
T+ W P + G + GY+VE +GS WVP N +P++ TV L FRV+
Sbjct: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
Query: 814 VNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVV 873
VN AG +P+ + V ++ +PP + H+ + + L P +G P +
Sbjct: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSI--SLAWREPAEGDPPSGYI 936
Query: 874 WTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE-YELSVQIENMKDTATIRIRVVEK 932
+ +R DT + + SG Y + IE K RIR V +
Sbjct: 937 ------------LEMRAE--DTKEWSKCTKIPISGTCYTVGGLIERQK--YFFRIRAVNE 980
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKA 972
AG + V+ G A+ APK D ++ + + V +A
Sbjct: 981 AG--VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRA 1018
Score = 45.8 bits (107), Expect = 2e-04
Identities = 70/300 (23%), Positives = 107/300 (35%), Gaps = 47/300 (15%)
Query: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVE 435
V+W KDGV K R K + + + D G Y+++ EA +
Sbjct: 1036 VIWQKDGVPT------KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
Query: 436 EK---------QLEVLQDIADLT---------VKASEQAVFKCEVSDEKVTGKWYKNGVE 477
+ L + +++ + V+ +A + D T WY
Sbjct: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDAS-TATWYTAAER 1148
Query: 478 VRPSK-RITISHVGR--FHKLV----IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
V +K +T GR + ++V I D P D D + LSAKL E K
Sbjct: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
Query: 531 -EYVPKQEPP-KIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+ P+ P K H V+ G + + G P P T KGD V T
Sbjct: 1209 WRHAPRFVTPLKPH------------TVLRGQDCTMTCAFLGNPRPTVTLYKGD-VNITA 1255
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
+ + VI + +D G Y++ V N +G+D +S L V D D IT
Sbjct: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASIT 1315
Score = 33.5 bits (75), Expect = 1.2
Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 10/129 (7%)
Query: 235 ITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVE-ISDPDLTLKWFKNG 293
I DL LK +K + + + F L P + V RG + + +P T+ +K
Sbjct: 1194 IQDLSAKLKPYEKK--DWRHAPRFVTPLKP-HTVLRGQDCTMTCAFLGNPRPTVTLYKGD 1250
Query: 294 QEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE------KCFTELFVKEPPVL 347
I +SK+ + + L I CTL D Y V V++E C ++ K+ +
Sbjct: 1251 VNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSV 1310
Query: 348 IVTPLEDQQ 356
+ + E Q
Sbjct: 1311 VASITESLQ 1319
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 275 bits (704), Expect = 1e-73
Identities = 222/790 (28%), Positives = 337/790 (42%), Gaps = 43/790 (5%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
++S +KW++NG+EIK KY FE G L I C L D+ Y V+D K
Sbjct: 12845 QLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRAR 12904
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
LFV+E PV I+ P +D G V E++++ +V W+++ + + + D +++
Sbjct: 12905 LFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD----KHQMM 12960
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEA--ELIVEEKQLEVLQDIA-----DLTVK 451
+GK H L D+ D+G Y+ I + A EL K QD+ LT+
Sbjct: 12961 SEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMV 13020
Query: 452 ASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
A K E +W+K E P TI I + + D+G Y V
Sbjct: 13021 VPYDAYPKAEA-------EWFK---ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIV 13070
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
+N I V + D + + G+K+ + +
Sbjct: 13071 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKI-IGYVVERR 13129
Query: 572 PPPVATWLKGDEVFTTTEGR-TRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS 630
TW+ + + E T ++K F + + R G ++ NPV + S
Sbjct: 13130 DIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE-PVETDNPV--EARS 13186
Query: 631 IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRW---MK 687
+ DVP PP V IT V L WEPP YDGG +T Y++E + K S RW M
Sbjct: 13187 KY----DVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 13242
Query: 688 LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHL 743
+ E + T T ++EG Y RV A N IGV +PS T PF+ PI S P++L
Sbjct: 13243 VRAEDLSATV---TDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNL 13298
Query: 744 IVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPT 803
D T ++ LKW PP + G I GY++E C EG + W+ N + V + V L
Sbjct: 13299 TSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK 13358
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP 863
G + L+RV N AG S+P+ + P+T + P + L + V + ++VP
Sbjct: 13359 GNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVI-VPNPITILVP 13417
Query: 864 FQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
G PRP W G L+T RV ++T + + RSD G Y L ++ +
Sbjct: 13418 STGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 13477
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I + V+ + P + ++ + + W+ P DDG S + GY V+K + W V
Sbjct: 13478 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 13537
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+ TV DL+ G EY F+V N CG + V + + P K
Sbjct: 13538 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWR 13597
Query: 1043 DFRMAPKFLT 1052
D FLT
Sbjct: 13598 DRTANSIFLT 13607
Score = 274 bits (701), Expect = 3e-73
Identities = 167/480 (34%), Positives = 243/480 (50%), Gaps = 13/480 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP+I LD + +V+ A LRL V+I G P P W K + + T R +IE
Sbjct: 25103 EPPEIELDADLR---KVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTD---RAQIEV 25156
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ VI++ R D GRY + + N G A + ++V+D P P + I V +D
Sbjct: 25157 TSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVT 25216
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L WEPP+ DGG +T Y+VE+++ + + + T+TT+ + EG Y RV A
Sbjct: 25217 LSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC-TKTTFRIENLQEGCSYYFRVLAS 25275
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G+ P+ T+P P P + + DVT T T+KW P G I GY+VE
Sbjct: 25276 NEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 25335
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
+GSE+W + V+ T+ L G +FRV VN GRS+P L PV R+I
Sbjct: 25336 TKGSEKW--STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEI 25393
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDT 895
P + LP H T+ K EQL + VPF+G+P+ V W K G L +T+RV+V +S T
Sbjct: 25394 KPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT 25450
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++A++ D G YEL V T I I V+++ GPP + + EV + + W
Sbjct: 25451 SLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 25510
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG +I Y V+K + + W V + TS + L G+EY FRV EN G S
Sbjct: 25511 PEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKS 25570
Score = 265 bits (678), Expect = 1e-70
Identities = 169/568 (29%), Positives = 272/568 (47%), Gaps = 23/568 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P++ LD + IVV AG R+ + G P P TW + + FT + +I
Sbjct: 24018 KLEAPELDLDSELR---KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD---KVQI 24071
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
EK V+ + I++ R D G+Y +K+ N G A + ++V+D P PP+ + + V +D
Sbjct: 24072 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDS 24131
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A LVWEPP+ DGG V Y++++++ + + ++ + ++T+++ + EG +Y RV
Sbjct: 24132 AFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKC-SKTSFKVENLTEGAIYYFRVM 24190
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N GV P P S P + + DV+ T+ +L W P G + GY+VE
Sbjct: 24191 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 24250
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G+E+W V C V L +G FRV N G+S+P L PV +++
Sbjct: 24251 MQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 24308
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDF 893
P ++LP + TY + GE L + +P G+PRP + W K G PL T+RV+V +
Sbjct: 24309 TIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETAT 24365
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
TV +++ + D G+Y ++ T + + V+EK GPP+ V EV ++
Sbjct: 24366 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 24425
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ P G +I Y V+K D T W V T+ ++ L G EY FR++ EN
Sbjct: 24426 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRY 24485
Query: 1013 GLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC 1069
G S DS V + G PF +M ++ P+ D G + +
Sbjct: 24486 GKSAPLDSKAVIVQYP-FKEPGPPGTPFVTSISKDQMLVQWHEPVND-----GGTKIIGY 24539
Query: 1070 AVRGHPKPKVVWMKNKMEIREDPKFLIT 1097
+ K ++W+K +D KF T
Sbjct: 24540 HLEQKEKNSILWVKLNKTPIQDTKFKTT 24567
Score = 261 bits (668), Expect = 2e-69
Identities = 175/561 (31%), Positives = 269/561 (47%), Gaps = 37/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+ G ++R S+R+T+ + KL I + D G+YT + S IKV
Sbjct: 29772 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 29826
Query: 531 EYVPKQEPPK--IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKG---DE 583
+ K PP I +D TS ++I+ EPP + L G ++
Sbjct: 29827 IILDKPGPPTGPIKIDEIDATS---------------ITISWEPPELDGGAPLSGYVVEQ 29871
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--VGEDVASIFLQV---VDV 638
G + + V S+F +E + + TN +G + S ++ + +
Sbjct: 29872 RDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRI 29931
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PPE ++I V D L W PP DGG VTGY+VERK+ + RW+++N T T Y
Sbjct: 29932 PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRY 29991
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
ST + EG+ YE RV A+NA G +PS +KP + PIAP +P + V D T T+ +L
Sbjct: 29992 RSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 30051
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
W P G + GYL+E EW NT P + +T+ +LP GA FRV+ N
Sbjct: 30052 AWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACN 30111
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
G EPA + V + E+ E P L ++ + G + L +P +GKP P WT
Sbjct: 30112 AGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWT 30171
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K G + + R + TS+ T +++A R DSG Y+L ++ + K I++RV+
Sbjct: 30172 KEGQDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNS 30230
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + V W+ P DDG ++I+GY +++ + W+ + R R TS V
Sbjct: 30231 PEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVK 30290
Query: 995 DLIVGNEYYFRVYTENICGLS 1015
L EY+FRV EN G+S
Sbjct: 30291 GLKENVEYHFRVSAENQFGIS 30311
Score = 252 bits (644), Expect = 1e-66
Identities = 177/599 (29%), Positives = 286/599 (47%), Gaps = 32/599 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ VKA E +++ + W K+G+E+ R I L + D D G
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTG 25858
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A + S +N + + K PP L+ +G T+E + + + + D
Sbjct: 25859 QYVLTLKNVAGTRSVAVN-----CKVLDKPGPPAGPLEINGLTAEKCSL--SWGRPQEDG 25911
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--V 624
+ V +T EG ++ +S + + +E + + N V
Sbjct: 25912 GADIDYYIVEKRETSHLAWTICEGELQM------TSCKVTKLLKGNEYIFRVTGVNKYGV 25965
Query: 625 GEDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKG 681
GE + S+ ++ +D VP PP ++ ITSV ++ L W P DGG ++GY++ER++K
Sbjct: 25966 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 26025
Query: 682 SQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPT 737
S RW+++N + + +ST + EG YE RV+A NA G+S PS T P + P+
Sbjct: 26026 SLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPS-ETSPLIRAEDPVFLP 26084
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
S P + D TT T+ W P G I GY VEY +W + + + +T
Sbjct: 26085 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYT 26143
Query: 798 VKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQ 857
+ L TGA +FRV VN G S+P+ + P +E E P + +R+T I K G
Sbjct: 26144 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 26203
Query: 858 LNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ VPF+G+P P V+W+K L T R +V T+D T + A R+DSG+Y L++Q
Sbjct: 26204 FTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNV 26262
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ T+ ++V++ GPP N+ V++V +A++ W P++DG + + Y ++K +
Sbjct: 26263 LSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKK 26322
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
W +V S V++L G YYFRV EN G+ G+ T +K IT KP
Sbjct: 26323 AWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV----GIPAETKEGVK--ITEKP 26375
Score = 249 bits (637), Expect = 8e-66
Identities = 181/600 (30%), Positives = 287/600 (47%), Gaps = 38/600 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
LTVKA V + + T W K+G ++P++ I ++ L + V +D G
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 19364
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
DYT + + S SA IK++ + K PP V NK+ D
Sbjct: 19365 DYTITAENSSGSKSAT-----IKLKVLDKPGPP---------------ASVKINKMYSDR 19404
Query: 567 SITGEPPPVA------TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
++ PP+ T D+ T+ ++ V +S +E E ++ I
Sbjct: 19405 AMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICA 19464
Query: 621 TNP--VGEDVASIFLQVVDVPDPP---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N VG+ V + + DPP + I+++ +D + W+PP DGG P+TGYL+
Sbjct: 19465 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLL 19524
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
E+++ + W K+N + E T ++T + EG YE RV A+N G +PS +K
Sbjct: 19525 EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARD 19584
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT-EPV 791
P P P V D T ++ +L W P G I GYLVE S+ WV N + +
Sbjct: 19585 PQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 19644
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
++ F V L + FRV VN G S+P+ + ++I PP+ L LR+T I
Sbjct: 19645 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 19704
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEY 910
+ G + L VP +G+P P++ W+K L D + ++++DFDT + D+G+Y
Sbjct: 19705 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 19764
Query: 911 ELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ 970
L+++ K TI ++V++ GPP+NV VKE+ +A V W+ P DG S I+ Y VQ
Sbjct: 19765 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 19824
Query: 971 KADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKT 1030
K D + W V TS V++L G Y+FRV+ EN G+ D PG +++ + +T
Sbjct: 19825 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD-PGETRDAVKASQT 19883
Score = 246 bits (628), Expect = 9e-65
Identities = 155/494 (31%), Positives = 245/494 (49%), Gaps = 17/494 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
+E + P + LD S + + IVV AG +R+ ++G+PPP TW + T
Sbjct: 16513 IEMKDRLVSPDLQLDASVR---DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER---TLP 16566
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT- 648
IE SS VI++ QR +G Y++ N GE +I + V+DVP P +
Sbjct: 16567 QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAH 16626
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
++ + L W P DGG P+T Y++E+++ + W + + V T +I+G
Sbjct: 16627 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV-TRQNATVQGLIQGKA 16685
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y R+ A N+IG+ P + T + PI P L V++VT T TL W PP G
Sbjct: 16686 YFFRIAAENSIGMG-PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDG 16744
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I Y++E L G+E++ + + +TVK L G +RV VNI G+ +P+
Sbjct: 16745 GSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF 16804
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAP-LDT 883
+P+T ++ PP + L R +VGE L + GKP+P+V W K A L+
Sbjct: 16805 CTKPITCKDELAPPTLHL--DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLED 16862
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVK 942
R H++T+ +A RSDSG+Y + V+ ++ VV++ GPP+ V
Sbjct: 16863 DRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFD 16922
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
EV ++ W+ P DDG S+I Y ++K + W V + T+C VS L+ G +Y
Sbjct: 16923 EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 16982
Query: 1003 YFRVYTENICGLSD 1016
FR++ EN+ G+SD
Sbjct: 16983 IFRIHAENLYGISD 16996
Score = 246 bits (627), Expect = 1e-64
Identities = 150/488 (30%), Positives = 235/488 (48%), Gaps = 9/488 (1%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
++E V + E P + L + + + AG LRL VS++G PPPV TW K
Sbjct: 29434 EIEPVERIEIPDLEL---ADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQG---IDL 29487
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
R I+ S +++ R D G+YTI+ N G+ A++ ++V D P P +V++
Sbjct: 29488 ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVK 29547
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V D + WE P DGG PV Y+VE K++ + R K ++T Y + ++EG +
Sbjct: 29548 EVSRDSVTITWEIPTIDGGAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTM 29606
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y RV N G+ +P + + P L V DVT +T TL W P G +
Sbjct: 29607 YYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRL 29666
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
GY++E C G+E W+ T TV +L G + LFR+ N G SEP
Sbjct: 29667 TGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 29726
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVH 887
VT++++ P I L ++T G + LV+P G+P P W G+ L ++ RV
Sbjct: 29727 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 29786
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWG 946
V T +R+ D+GEY L ++ + TI++ +++K GPP + + E+
Sbjct: 29787 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 29846
Query: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRV 1006
T+ + W+ P+ DG + + GY V++ D W V E ++ + L GNEY FRV
Sbjct: 29847 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 29906
Query: 1007 YTENICGL 1014
N G+
Sbjct: 29907 AATNRFGI 29914
Score = 243 bits (620), Expect = 8e-64
Identities = 162/502 (32%), Positives = 240/502 (47%), Gaps = 27/502 (5%)
Query: 527 EIKVEYVPKQ--EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEV 584
E+K PK+ EPP+I LD S + ++V AG +RL + G P P TW K
Sbjct: 18590 ELKEAIKPKEILEPPEIDLDASMR---KLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID 18646
Query: 585 FTTTEGRTRIEKRVDCSSF-VIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
+G+ + VD +F VI ++ R+D G+Y++ + NP GE + ++V+D P P
Sbjct: 18647 NVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVS 18703
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++++ V + + W PP DGG VT Y+VE+++ + W + EV +T++ T +
Sbjct: 18704 DLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNL 18762
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSE---PLHLIVEDVTDTTTTLKWRPP 760
+ G Y RV AVN G P+ KP + P SE P L V ++T + TL W PP
Sbjct: 18763 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 18822
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANT----EPVERCGFTVKNLPTGARILFRVVGVNI 816
R G IDGY+ Y EE PA+ V+ V L G + FRV N
Sbjct: 18823 LRDGGAKIDGYITSY----REEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNA 18878
Query: 817 AGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P +E PPKI +P + K G++L + GKP P W K
Sbjct: 18879 VGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKK 18934
Query: 877 GGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G + T S + V +D ++ ++ R DSG Y L+ + + DT I++ V++ GP
Sbjct: 18935 GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGP 18994
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + W P +DG S I Y V+K D +W TSC V
Sbjct: 18995 PQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVG 19054
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
LI G EY FRV EN G+S+
Sbjct: 19055 KLIPGQEYIFRVRAENRFGISE 19076
Score = 239 bits (610), Expect = 1e-62
Identities = 152/487 (31%), Positives = 236/487 (48%), Gaps = 22/487 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P I LD + N + AG LRL V I G P P W K D G R
Sbjct: 22936 KLEAPDIDLDLELRKIIN---IRAGGSLRLFVPIKGRPTPEVKWGKVD-------GEIRD 22985
Query: 595 EKRVDCSS----FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSV 650
+D +S V+++ R D G+YT+ + N G A + ++V+D P PP +++T +
Sbjct: 22986 AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEI 23045
Query: 651 GEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYE 710
+D + WEPP+ DGG + Y+VE+++ + + + + +++ ++ EG Y
Sbjct: 23046 TKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCH-KNSWKIDQLQEGCSYY 23104
Query: 711 MRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDG 770
RV A N G+ P+ P P + V+DVT + +L W P G I
Sbjct: 23105 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 23164
Query: 771 YLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
Y+VE + SE+W + V+ + NL G LFRVV VN GRS+P +LA P+
Sbjct: 23165 YIVEMQAKHSEKW--SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIV 23222
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVR 889
+++ P + + +Y +VG+ L + VP G+P+P + WTK G PL T+R++V
Sbjct: 23223 AKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 23279
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTN 948
S T +++ + D G+Y ++V + TA+I I ++K PP V +V +
Sbjct: 23280 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES 23339
Query: 949 ALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYT 1008
+ W P G +I Y VQK D T W V T+ V+ L G EY FR++
Sbjct: 23340 ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFA 23399
Query: 1009 ENICGLS 1015
EN G S
Sbjct: 23400 ENRYGQS 23406
Score = 238 bits (607), Expect = 2e-62
Identities = 178/616 (28%), Positives = 277/616 (44%), Gaps = 39/616 (6%)
Query: 429 EAELIVEEKQLEVLQDIA---DLTVKASEQAVFKCEVSDEK-VTGKWYKNGVEVRPSKRI 484
EAE + E K+ + I +T+KA ++ + V + T KW K EV S +
Sbjct: 18886 EAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL 18945
Query: 485 TISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLD 544
+ L+I DV +D G Y+ + S+ + +IKV + PP+ D
Sbjct: 18946 AVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKVVVMDAPGPPQPPFD 19000
Query: 545 CSGKTSENA-----IVVVAGNKLRLDVSITGEPPPVATWLKGDEVF---TTTEGRTRIEK 596
S ++ I + G +IT +GD V + T+ R+ K
Sbjct: 19001 ISDIDADACSLSWHIPLEDGGS-----NITNYIVEKCDVSRGDWVTALASVTKTSCRVGK 19055
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ E R+ I + VA VP P+ R+T V +D
Sbjct: 19056 LIPGQEYIFRVRA---ENRFGISEPLTSPKMVAQF---PFGVPSEPKNARVTKVNKDCIF 19109
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
+ W+ P DGG P+ GYL+ERK++ S W+K N + T Y ++EG+ Y R++A+
Sbjct: 19110 VAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 19169
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G S PS T+ P P V DVT +T +L W P G I GY VE C
Sbjct: 19170 NKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC 19229
Query: 777 LEGSEEWVPANTEP--VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
++WV NT P + + +T L A+ FR + S P+ + PVTI
Sbjct: 19230 KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE 19289
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA---PLDTSRVHVRTS 891
PP+I L ++ K G + L GKP P V W K G P + ++ ++ +
Sbjct: 19290 NVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN 19349
Query: 892 DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALV 951
F R DSG+Y ++ + + +ATI+++V++K GPP +V + +++ A++
Sbjct: 19350 LCTLELF--SVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAML 19407
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P +DG SEI Y V K + W V TSC+V LI G+EY FR+ EN
Sbjct: 19408 SWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENK 19467
Query: 1012 CGLSD----SPGVSKN 1023
G+ D P ++KN
Sbjct: 19468 YGVGDPVFTEPAIAKN 19483
Score = 238 bits (606), Expect = 3e-62
Identities = 157/496 (31%), Positives = 232/496 (46%), Gaps = 19/496 (3%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP++ LD + ++ + G+ LRL I G P P TW K D T + RI+
Sbjct: 17214 EPPELILDANMAREQH---IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT---KARIDV 17267
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
S I +A ED G Y++ V NP G S+ + V+D P PP + ++ + +D
Sbjct: 17268 TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 17327
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W+ P+ DGG +T Y+VER+ S +W L+ + ++ + + EG Y RV A
Sbjct: 17328 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAE 17386
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G KP P+ P P L DV T +L W P+R G I GYLV
Sbjct: 17387 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 17446
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
EY EG+++W+ T C V L G FRV NI G P T P+ +E
Sbjct: 17447 EYQEEGTQDWIKFKTVTNLEC--VVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 17503
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH-VRTSD 892
PP + L L + + K G + +G P P WT G+ + T + V T +
Sbjct: 17504 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 17563
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALV 951
F +V ++ R D+GEY+++V T + + V++ GPP + + +V + +
Sbjct: 17564 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 17623
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
WQ PKDDG S ++ Y V+K D + W V + T + L G EY FRV EN
Sbjct: 17624 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 17683
Query: 1012 CG----LSDSPGVSKN 1023
G L +P V+K+
Sbjct: 17684 IGVGPPLDSTPTVAKH 17699
Score = 234 bits (598), Expect = 3e-61
Identities = 149/496 (30%), Positives = 239/496 (48%), Gaps = 18/496 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
VE V ++ P LD + + +VV AG +R+ V I G P P TW K + +
Sbjct: 20765 VEIVEREMAPDFELDAELRRT---LVVRAGLSIRIFVPIKGRPAPEVTWTKDN---INLK 20818
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
R IE + +I R D G++ + + NP G+ + ++V+D P P +R T
Sbjct: 20819 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTD 20878
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ +D L W+ P+ DGG +T Y+VE+++ + + + + TY+ T + EG Y
Sbjct: 20879 ITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH-KCTYKVTGLSEGCEY 20937
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
RV A N G+ +P+ T+P S P L + D+T +T +L W P G I
Sbjct: 20938 FFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKIT 20997
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
GY++E +GS++W T C V+NL G F+V+ VN AGRS P ++PV
Sbjct: 20998 GYVIEAQRKGSDQWTHITTVKGLEC--VVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPV 21054
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHV 888
++E P++ L ++ I K G+ + + +P G+P+P V W KG L T RV+
Sbjct: 21055 IVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNF 21114
Query: 889 RTSDFDTVFFVRQAARSDSGEYELSVQ--IENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
T+ T+ + + RSDSG Y L+ + + + D TI++ + GPP + EV
Sbjct: 21115 ETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI--PGPPTGPIKFDEVS 21172
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
W P++DG I Y V+ + W + T+ + L G EY FR
Sbjct: 21173 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 21232
Query: 1006 VYTENICGLSDSPGVS 1021
V +N G+ PG++
Sbjct: 21233 VKAQNRYGV--GPGIT 21246
Score = 232 bits (592), Expect = 1e-60
Identities = 161/551 (29%), Positives = 248/551 (45%), Gaps = 28/551 (5%)
Query: 469 GKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
G W+K E R T++ + G +K + + +GD V
Sbjct: 28298 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG------------- 28344
Query: 527 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 586
++ V + P++ +D + K + VV AG +RL ++ G P P A W K D +
Sbjct: 28345 --TIKAVDRLTAPELDIDANFKQTH---VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 28399
Query: 587 TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVR 646
R I S+ +E+ R D G+YT+ V N G + ++V+D P PP +
Sbjct: 28400 L---RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPIT 28456
Query: 647 ITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEG 706
V A L+W+ P+ DGG + Y+VE+++ + W ++ E T ++ + EG
Sbjct: 28457 FKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDLAEG 28515
Query: 707 ILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAG 766
+ Y RV AVN GV +P +P + + P L V D + ++ L W P+ G
Sbjct: 28516 VPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGS 28575
Query: 767 GIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA 826
I GYL+E +GS+ WV A ++ FTV+ L FRV N AG SEP
Sbjct: 28576 RITGYLLEMRQKGSDFWVEAG--HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 28633
Query: 827 QPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSR 885
V I+E P L Q K G + VP G+P P+V W L +T R
Sbjct: 28634 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDR 28693
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
V + T+ T V+ + R DSG Y L+++ T ++ + V+ + GP + V V
Sbjct: 28694 VSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV 28753
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
+ ++ W PKD G +EI Y V+K + T W V + T V+ L EY F
Sbjct: 28754 SAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSF 28813
Query: 1005 RVYTENICGLS 1015
RV +EN G+S
Sbjct: 28814 RVSSENRFGVS 28824
Score = 231 bits (588), Expect = 4e-60
Identities = 141/480 (29%), Positives = 230/480 (47%), Gaps = 7/480 (1%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ + V+ N + + V TG P P ATW GD+V T + R +++ + VI ++R
Sbjct: 13401 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD-RVKMKTLSAYAELVISPSER 13459
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
D+G YT+K+ N V I + V+ P P+ ++ + +D L WEPP DGG P+
Sbjct: 13460 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 13519
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
TGY+VE+++ + W K+ + T+ + +++G Y +V A N G +P+ +P
Sbjct: 13520 TGYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEP 13578
Query: 731 FMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPAN 787
P + P ++ D T + L W PP G I GY+VE C GS++WV
Sbjct: 13579 VNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 13638
Query: 788 TEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
EPV V L G +RV +N G S+P+ + + + E P+I L L
Sbjct: 13639 -EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL 13697
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSD 906
K G ++ L GKP P++ WTK L R+ + + + + RSD
Sbjct: 13698 AGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSD 13757
Query: 907 SGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966
+G Y + + TA + + V++K GPP + +V + L+ W P+DDG S+I
Sbjct: 13758 TGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITN 13817
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y V++ + W + + T+ + LI EY FRV EN+ G+ + S TA+
Sbjct: 13818 YVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAK 13877
Score = 228 bits (581), Expect = 3e-59
Identities = 138/484 (28%), Positives = 226/484 (46%), Gaps = 11/484 (2%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
++E P +D + + ++V AG + V G P P W K D T R +
Sbjct: 26180 REEEPLFDIDSEMRKT---LIVKAGASFTMTVPFRGRPVPNVLWSKPD---TDLRTRAYV 26233
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ +S IE+A R D G+YT+ + N + ++ ++V+D P PP + + V ++
Sbjct: 26234 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKES 26293
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A+L W+ P DGG PV Y +E+++ + W+ + +Y+ T + EG +Y RV
Sbjct: 26294 AVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKVTNLQEGAIYYFRVS 26352
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N GV P+ + S P L V ++ + +L W P G I Y+VE
Sbjct: 26353 GENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVE 26412
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G + WV + V L + FRV N AG S+P L PV I+E
Sbjct: 26413 ALEKGQKNWVKCAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQ 26470
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDF 893
EPP+I + T + G L + +P GKP P+V ++ G PL T R + +
Sbjct: 26471 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 26530
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+ ++++ +D+G YE++ + A I I V+++ GPP V++ ++ + ++
Sbjct: 26531 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLK 26590
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ PK DG S++ Y + K + T W V T V L G EY FR+ EN
Sbjct: 26591 WEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRF 26650
Query: 1013 GLSD 1016
G+SD
Sbjct: 26651 GISD 26654
Score = 226 bits (577), Expect = 7e-59
Identities = 133/383 (34%), Positives = 202/383 (52%), Gaps = 10/383 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE-VFTET 696
VPD P+ +T V +D A++ W P +DGGKP+T Y++E+++ S+RW ++ + + T
Sbjct: 17011 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 17069
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTT 753
+ ++EG YE RV A N IG+ PS +KP PIA S P++ D T +
Sbjct: 17070 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 17129
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT---VKNLPTGARILFR 810
L W+PP G I GY+VEY G EEW AN P E C T V L G FR
Sbjct: 17130 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTP-ESCPETKYKVTGLRDGQTYKFR 17188
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V+ VN AG S+PA + +PV +++ EPP++ L ++ + KVG+ L L +G P P
Sbjct: 17189 VLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP 17248
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
+V W K T + + + + +R AA D G Y L+V+ T ++++ V+
Sbjct: 17249 KVTWKKEDRDAPT-KARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVL 17307
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTS 990
+K GPP ++ V E+ + + W+ P DDG S I Y V++ D + +W + ++ S
Sbjct: 17308 DKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKS 17367
Query: 991 CTVSDLIVGNEYYFRVYTENICG 1013
L GN+Y FRV EN G
Sbjct: 17368 HFAKHLNEGNQYLFRVAAENQYG 17390
Score = 225 bits (574), Expect = 2e-58
Identities = 147/490 (30%), Positives = 230/490 (46%), Gaps = 22/490 (4%)
Query: 534 PKQE----PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK--GDEVFTT 587
PK E PP+I LD + + + A LRL V I G P P W + G+ +
Sbjct: 21849 PKAEDRMLPPEIELDADLR---KVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--- 21902
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ IE + ++ + R D G+Y + V N G A + ++V+D P PP+ +++
Sbjct: 21903 --DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKV 21960
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
V + L W+PP+ DGG + Y+VE+++ + + + +T+++ ++ EG
Sbjct: 21961 KEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCH-KTSWKVDQLQEGC 22019
Query: 708 LYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
Y RV A N G+ P+ + P + + DVT + +L W P G
Sbjct: 22020 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSR 22079
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
I GY+VE +GS++W T V T+ L G FRV N G S+P L+
Sbjct: 22080 ILGYIVEMQTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSV 22137
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRV 886
PV +++ PP +L L T+ GE L + VPF G+P P V W K PL T+RV
Sbjct: 22138 PVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRV 22194
Query: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
+ +++ +++ ++ A R D G Y + + + T+ + V++K GPP V + EV
Sbjct: 22195 NAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT 22254
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
+ + W PK DG S I Y V+K D T W V T+ L G EY FR
Sbjct: 22255 ADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 22314
Query: 1006 VYTENICGLS 1015
+ EN G S
Sbjct: 22315 IAAENRYGKS 22324
Score = 219 bits (557), Expect = 2e-56
Identities = 145/484 (29%), Positives = 237/484 (48%), Gaps = 18/484 (3%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE-K 596
PP+ LD + + +++ AG +RL V + G PPP TW K + R ++ K
Sbjct: 19690 PPEGELDADLRKT---LILRAGVTMRLYVPVKGRPPPKITWSKPN---VNLRDRIGLDIK 19743
Query: 597 RVDCSSFV-IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
D +F+ E+ + D G+Y + + N G+ +I ++V+D P PP V + + +D A
Sbjct: 19744 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 19803
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WEPP+ DGG P+ Y+V+++ + W + E ++T++ + EG Y RVFA
Sbjct: 19804 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFA 19862
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPL-HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N G+ P T+ + + T P+ L V V+ ++ ++ W+ P+ G I GY+V+
Sbjct: 19863 ENEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 19921
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+ E ++ + ++ ++ K+L G FRV N G P+ + V R+
Sbjct: 19922 FLTEENKWQRVMKSLSLQ---YSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDD 19976
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDT-SRVHVRTSDF 893
P + L Y+ K L +P +GKP P V W KG PL T +RV V +S
Sbjct: 19977 VVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAV 20036
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+T V +SD+G+Y ++++ TI I+VV K G P + EV ++
Sbjct: 20037 NTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLK 20096
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W PKDDG SEI Y ++K D +W + T+ V+ L G EY FRV EN
Sbjct: 20097 WAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKY 20156
Query: 1013 GLSD 1016
G+ +
Sbjct: 20157 GVGE 20160
Score = 218 bits (556), Expect = 2e-56
Identities = 158/516 (30%), Positives = 233/516 (45%), Gaps = 54/516 (10%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+++ V QE P+I LD + V AG K+ L ++TG+P P TW K D +
Sbjct: 13678 EIQAVDTQEAPEIFLDVKLLAG---LTVKAGTKIELPATVTGKPEPKITWTKADMILKQD 13734
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
+ R IE S+ I ++R D G Y I+ N G A + + V+D P PP A IT
Sbjct: 13735 K-RITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDIT 13793
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V + +L W PP DGG +T Y+VER+ S+ W KL+ V +T +++TK+I
Sbjct: 13794 DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKLIPNKE 13852
Query: 709 YEMRVFAVNAIGVSQPSMNTKPF---MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGA 765
Y RV A N GV +P + P P P L D+T TL W P+ G
Sbjct: 13853 YIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 13911
Query: 766 GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATL 825
I GY VE +++WV N PV+ + VK L + FRV+ N+AG +P+
Sbjct: 13912 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 13971
Query: 826 AQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPL 881
+P+ I++ +PP V GK ++ WTK GGA +
Sbjct: 13972 TEPILIKDPIDPP----------------WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKI 14015
Query: 882 DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG------- 934
++ + + + D +VR A + ++ L +E + + R+R V KAG
Sbjct: 14016 ESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQE--YSFRVRAVNKAGESEPSEP 14071
Query: 935 --------------PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF 980
PP + V + A ++W P+ DG S I Y V+K D + W
Sbjct: 14072 SDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQ 14131
Query: 981 NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T CTV+ L G+ Y FRV EN G SD
Sbjct: 14132 TVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 14167
Score = 218 bits (556), Expect = 2e-56
Identities = 180/670 (26%), Positives = 295/670 (44%), Gaps = 50/670 (7%)
Query: 364 EMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVIT 423
E VE +G Q W G+ T E + ++ +L F + ++G +T
Sbjct: 27496 EYVVERKGKGEQT-WSHAGISKTCE------IEVSQLKEQSVLEFRVFAKNEKGLSDPVT 27548
Query: 424 NGGQCEAELIVEEKQLEVLQDI--ADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRP 480
G ELI+ + L DI A +TV+ + + K + W K+G+ ++
Sbjct: 27549 IGPITVKELIITPEV--DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 27606
Query: 481 SKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPK 540
S+ + S L I + + E G YT + D ++ + + + PK
Sbjct: 27607 SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP--- 27663
Query: 541 IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGR--TRIEKRV 598
+ ++++ D I P G+ + E R ++ ++
Sbjct: 27664 ----------------IRFDEIKADSVILSWDVPEDNG-GGEITCYSIEKRETSQTNWKM 27706
Query: 599 DCSS-----FVIESAQREDEGRYTIKVTNPVGED---VASIFL--QVVDVPDPPEAVRIT 648
CSS F + + ++ E ++ ++ N G V+SI + +P PP I
Sbjct: 27707 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY 27766
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
+V D L W+ P+YDGG VTG+ VE+K++ S W K+N + Y +T ++EG+
Sbjct: 27767 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 27826
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y+ RV+A N+ G+S PS +K + ++P P DVT T TLKW PP R G I
Sbjct: 27827 YQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKI 27886
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQ 827
GY +E +G+E WV N V C +TV L G R FR++ N G S P+ +
Sbjct: 27887 VGYSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSG 27945
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH 887
+ R+ PP + I K GE L + QG+P P+V W K G ++ R++
Sbjct: 27946 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMN 28004
Query: 888 VRTSDF--DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
+ +D T FVR A R G Y + + + A I+++V + G + + +
Sbjct: 28005 MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNI 28064
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
G + W AP +DG + I Y ++K + + W + ++ S T LI GNEY F
Sbjct: 28065 TGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQF 28124
Query: 1005 RVYTENICGL 1014
RV N G+
Sbjct: 28125 RVSAVNKFGV 28134
Score = 218 bits (555), Expect = 3e-56
Identities = 160/568 (28%), Positives = 254/568 (44%), Gaps = 31/568 (5%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+K+ V ++ + R+ L I D ED G Y L+ SA + V
Sbjct: 22181 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVV-----KLTNSAGEAIETLNV 22235
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITG-----EPPPVATWLKGDEVF 585
+ K PP + T+++ + K SI TW ++
Sbjct: 22236 IVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW----QIV 22291
Query: 586 TTTEGRTRIEK---RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+ T RT I+ + C + A G+ T + P ++ VP PP
Sbjct: 22292 SATVARTTIKACRLKTGCE-YQFRIAAENRYGKSTYLNSEP------TVAQYPFKVPGPP 22344
Query: 643 EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTK 702
+T D + W P+ DGG V GY +ERK++ S W+KLN +T +++T
Sbjct: 22345 GTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTG 22404
Query: 703 MIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNR 762
+ EG+ YE RV A N +G+ +PS ++ ++ P P VT + TL+W+ P
Sbjct: 22405 LEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTY 22464
Query: 763 IGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSE 821
G I GY+VE W+ A+ + F V L R FRV+ N AG SE
Sbjct: 22465 DGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 22524
Query: 822 PATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL 881
P+ +T R+ +PP+I + + T + GE + GKP P + W KG L
Sbjct: 22525 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 22584
Query: 882 -DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-V 939
+T+R+ ++++DF T V+ A R DSG Y L + + + T+ ++V+++ GPP V
Sbjct: 22585 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPV 22644
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVG 999
++ V + W+ P DG S+I+ Y V++ + + W V + SC V+ L+ G
Sbjct: 22645 VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG 22704
Query: 1000 NEYYFRVYTENICG----LSDSPGVSKN 1023
NEY FR+ N G L P V+KN
Sbjct: 22705 NEYTFRIMAVNKYGVGEPLESEPVVAKN 22732
Score = 218 bits (554), Expect = 3e-56
Identities = 167/650 (25%), Positives = 284/650 (43%), Gaps = 55/650 (8%)
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRIT 485
+C+ +L+ +L+V + I L VKA F + V T KW +G E++ + T
Sbjct: 17500 ECQEKLVPPSVELDV-KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 17558
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDC 545
+ L I + D G+Y A S + ++ + V PP ++
Sbjct: 17559 VETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP-----GPPTGPINI 17613
Query: 546 SGKTSENAIVVVAGNKLRLDVSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVD 599
T E+ ++I+ +PP PV ++ ++ T + +
Sbjct: 17614 LDVTPEH-------------MTISWQPPKDDGGSPVINYIV-EKQDTRKDTWGVVSSGSS 17659
Query: 600 CSSFVIESAQREDEGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ I Q+ E + ++ N +G + ++ P PP +T + E+
Sbjct: 17660 KTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENA 17719
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A + W P DGG P+TGY +ER++ + +W+++N + + T + EG YE RVF
Sbjct: 17720 ATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVF 17778
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G+S+PS ++ P PI P P++ ++D + T L W P G I GY
Sbjct: 17779 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 17838
Query: 772 LVEYCLEGSEEWVPANT-EPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
+VE G+ +W N E + +C F V L G FR+ NI G EP LA+ V
Sbjct: 17839 VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVI 17898
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRT 890
++I PP++ L R +VG+ + ++ +G+P P + WTK G L +
Sbjct: 17899 AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI 17958
Query: 891 SDFDTV-FFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
D V +++A R+D G+Y +S + + + + V+++ GP N+ V V N
Sbjct: 17959 QDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENC 18018
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W+ P D+G SEI + V+ W ++ + ++L+ NEYYFRV E
Sbjct: 18019 TISWENPLDNGGSEITNFIVEYRKPNQKGW-SIVASDVTKRLIKANLLANNEYYFRVCAE 18077
Query: 1010 NICGLS---------------DSPGVSKNTARILKTGITFKPFEYKEHDF 1044
N G+ D PG +N I G TF +++ D+
Sbjct: 18078 NKVGVGPTIETKTPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDY 18126
Score = 217 bits (553), Expect = 4e-56
Identities = 125/382 (32%), Positives = 192/382 (50%), Gaps = 3/382 (0%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP PP ++T+V +D + W P+ DGG P+ GY VERK++ W ++ +
Sbjct: 21258 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 21317
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKW 757
++S+ + +GI YE RV A N G S+PS ++P + + P P + ++T T TLKW
Sbjct: 21318 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKW 21377
Query: 758 RPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIA 817
P G I Y+VE + W+ AN + FTV L A FRV+ N A
Sbjct: 21378 AKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAA 21437
Query: 818 GR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P+ + +T R+ E PKI++ + T I K GE L G+P P + W+K
Sbjct: 21438 GAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSK 21497
Query: 877 GGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G L+ T+++ ++ +DF T + + R DSG Y L+ ++V+++ GP
Sbjct: 21498 DGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP 21557
Query: 936 PIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + V EV ++ W P DDG ++I Y VQK + + W NV + T V+
Sbjct: 21558 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVT 21617
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 21618 KLLKGNEYIFRVMAVNKYGVGE 21639
Score = 217 bits (552), Expect = 6e-56
Identities = 155/560 (27%), Positives = 257/560 (45%), Gaps = 34/560 (6%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
E P+I LD + +TS ++ AG +++ + G PPP TW K DE ++ R IE
Sbjct: 27267 EAPEIDLDVALRTS---VIAKAGEDVQVLIPFKGRPPPTVTWRK-DEKNLGSDARYSIEN 27322
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS-IFLQVVDVPDPPEAVRITSVGEDWA 655
S I R D G+Y + + N VGE +S + ++V+D P + +++ V
Sbjct: 27323 TDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV 27382
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L+W+PP+ DGG P+ Y++E++ + W ++ + + T+++ + E + RV A
Sbjct: 27383 TLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLA 27441
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY 775
N IG+ +P T+P + L ++D T T+ L W P+ G I Y+VE
Sbjct: 27442 ENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 27501
Query: 776 CLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIA 835
+G + W A + C V L + + FRV N G S+P T+ P+T++E+
Sbjct: 27502 KGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELI 27558
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFD 894
P++ L ++G ++L +P++GKP+P + W K G PL S V ++
Sbjct: 27559 ITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK 27618
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV---VEKAGPPIN----VMVKEVWGT 947
++ A + G+Y + + D A RI V V GPP + E+
Sbjct: 27619 ITLSIKNAKKEHGGKYTV------ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKAD 27672
Query: 948 NALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVY 1007
+ ++ W P+D+G EI Y ++K + W V T+ V +L+ EY FRV
Sbjct: 27673 SVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVR 27732
Query: 1008 TENICGLS----DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGY 1063
EN G+S S V+K+ RI G KP Y M+ + P+ D G
Sbjct: 27733 AENRYGVSQPLVSSIIVAKHQFRI--PGPPGKPVIYNVTSDGMSLTWDAPVYD-----GG 27785
Query: 1064 SAALNCAVRGHPKPKVVWMK 1083
S V + ++W K
Sbjct: 27786 SEVTGFHVEKKERNSILWQK 27805
Score = 216 bits (551), Expect = 8e-56
Identities = 174/617 (28%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 434 VEEKQLEVLQDIADLTV-KASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR 491
VE +++V D + KA E + +VS T +W K+G E+ + ++ I
Sbjct: 21456 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 21515
Query: 492 FHKLVIDDVRPEDEGDYTFV---PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
LV D D G YT P G+A + V+ + + PP+ L +
Sbjct: 21516 STNLVNKDSTRRDSGAYTLTATNPGGFAKHI--------FNVKVLDRPGPPEGPLAVTEV 21567
Query: 549 TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF-----TTTEGRTRIEKRVDCSSF 603
TSE + ++ PP K D T+ T + V +
Sbjct: 21568 TSEKCV-------------LSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 21614
Query: 604 VIESAQREDEGRYTIKVTNP--VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILV 658
+ + +E + + N VGE + S + V+ PDPP+ +T++ +D ++
Sbjct: 21615 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVC 21674
Query: 659 WEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
W P DGG + Y+VER+ K QRW+K N + T+ Y+ + + EG YE R+ A NA
Sbjct: 21675 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 21734
Query: 719 IGVSQPSMNTKPFMPIAPT----SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
G+S PS T PF T P + V D + ++ ++ W P G I GY+VE
Sbjct: 21735 AGISAPS-PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVE 21793
Query: 775 YCLEGSEEW-VPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
L +EW + ++ +T+ L R+ +N G EPA + +
Sbjct: 21794 IALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAED 21853
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKG-GAPLDTSRVHVRTSD 892
PP+I L LR+ + L L VP +G+P P+V W + G LD + + TS
Sbjct: 21854 RMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIE-STSS 21912
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVE 952
+ T+ V R DSG+Y L+V+ + +A + +RV++ GPP ++ VKEV T+ +
Sbjct: 21913 Y-TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLT 21971
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W P DG S+I Y V+K + + V TS V L G YYFRV EN
Sbjct: 21972 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEY 22031
Query: 1013 GLSDSPGVSKNTARILK 1029
G+ G+ TA +K
Sbjct: 22032 GI----GLPAETAESVK 22044
Score = 215 bits (548), Expect = 2e-55
Identities = 150/495 (30%), Positives = 223/495 (45%), Gaps = 24/495 (4%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
QEPP + LD S K I ++AG LR+ +TG P P W K E + R I+
Sbjct: 15099 QEPPAVELDVSVK---GGIQIMAGKTLRIPAVVTGRPVPTKVWTK--EEGELDKDRVVID 15153
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S +I+ A R+D GRY I TN G A+ ++V DVP P ++
Sbjct: 15154 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 15213
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYESTKMIEGILYEMRVF 714
+L W P DGG +TG+++ERK W + + TE + + T ++EG Y+ RV
Sbjct: 15214 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ---PIETERSKCDITGLLEGQEYKFRVI 15270
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G P + P + P+ P + P L + T +T TL W+ P G I GY
Sbjct: 15271 AKNKFGCG-PPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGY 15329
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
++E ++ N F V+NL FRV VN G SEP +L V I
Sbjct: 15330 IIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-SLPLNVVI 15388
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGA-------PLDT 883
++ PP I+L +R I+ K GE +++ G P P++ W+K L
Sbjct: 15389 QDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQI 15448
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKE 943
++ V S+ T + +A R D G Y ++ + + V ++ PP N+ V +
Sbjct: 15449 TKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 15508
Query: 944 VWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIVGNE 1001
+ + + W AP D+G SEI Y + K D +K EW V + LI +
Sbjct: 15509 IKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQ 15568
Query: 1002 YYFRVYTENICGLSD 1016
Y FRV N G+SD
Sbjct: 15569 YEFRVRAVNKYGISD 15583
Score = 213 bits (543), Expect = 6e-55
Identities = 157/584 (26%), Positives = 263/584 (45%), Gaps = 34/584 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
L +K+ E K V V W+K+GVE+ + I+ V L + D + G
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRL-- 564
YT + S A++ ++KV+ P + I + G K+ L
Sbjct: 28028 VYTVEAKNASGSAKAEI---KVKVQDTPGKVVGPIRF-----------TNITGEKMTLWW 28073
Query: 565 DVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN-- 622
D + P+ ++ ++ T+ IE + + S+ +E ++ + N
Sbjct: 28074 DAPLNDGCAPITHYII-EKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKF 28132
Query: 623 ----PVGED--VASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
P+ D VA I V D P PE IT + L W P DGG + Y++E
Sbjct: 28133 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITG---NSITLTWARPESDGGSEIQQYILE 28189
Query: 677 RKKKGSQRWMK-LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
R++K S RW+K ++ +ET ++ T + EG YE V A NA GV S ++
Sbjct: 28190 RREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE 28249
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
P+ P P + V D + TT +L+W P G I GY++E C +W N E
Sbjct: 28250 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV 28309
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
+ +TV +L G FRV +N AG+ + + + + P++ + + +QT++
Sbjct: 28310 KTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVV 28369
Query: 853 KVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ G + L + +QG+P P VW+K + L + R + T+D + V R+D+G+Y L
Sbjct: 28370 RAGASIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTL 28428
Query: 913 SVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKA 972
+V+ + + T ++V++ GPP + K+V +A + W AP DG + I Y V+K
Sbjct: 28429 TVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKR 28488
Query: 973 DKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + E+ V+DL G YYFRV N G+ +
Sbjct: 28489 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 28532
Score = 213 bits (542), Expect = 8e-55
Identities = 131/391 (33%), Positives = 192/391 (49%), Gaps = 16/391 (4%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PDPPE +T V ++ +VW PP YDGGK +TGY +E+K+K S RW+ +N E
Sbjct: 18399 PDPPE---VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 18455
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
+ ++ Y+ RV A N IG+ +PS+ ++P + PI P P + V D T + TL
Sbjct: 18456 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITL 18515
Query: 756 KWRPPNRIGAGGIDGYLVEY-----CLEGSEEWVPAN-TEPVERCGFTVKNLPTGARILF 809
W P G I GY+VE E W N + R FTV +L F
Sbjct: 18516 GWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEF 18575
Query: 810 RVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPR 869
RV N G PA L + + +EI EPP+I L +R+ I + G + L +G+P
Sbjct: 18576 RVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPA 18635
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV 929
P+V W K G + V D + + R DSG+Y L++ + + +RV
Sbjct: 18636 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 18695
Query: 930 VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
++ GP ++ V +V T+ V W P++DG S++ Y V+K + W V + T
Sbjct: 18696 LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKT 18755
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGV 1020
S V++L+ GNEYYFRV N G PGV
Sbjct: 18756 SFHVTNLVPGNEYYFRVTAVNEYG----PGV 18782
Score = 211 bits (538), Expect = 2e-54
Identities = 145/521 (27%), Positives = 236/521 (45%), Gaps = 40/521 (7%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW--------LKGDEVFTT 587
QE P++ +D +++ +V AG+++R+ I G P P ++W D V
Sbjct: 15805 QEEPEVFIDIG---AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDI 15861
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
E ++E + S +I +R G+Y+I N G+ A+ ++V+DVP PP+ +++
Sbjct: 15862 PED-AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKV 15920
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
+ + L W+ P DGG + GY++E++ + W K+N + TT+ ++
Sbjct: 15921 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDC-GSTTFVVPDLLSEQ 15979
Query: 708 LYEMRVFAVNAIGVSQP---SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y RV A N G+ P T PI P P+ L + +T T L W+PP G
Sbjct: 15980 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDG 16039
Query: 765 AGGIDGYLVEYCL------EGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG 818
+ Y+VE CL E W N VE FTV++L G FRV VN AG
Sbjct: 16040 GSPVTHYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAG 16098
Query: 819 RSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
S+P+ P + PP I L + + G +N+V +G P P + W K
Sbjct: 16099 VSKPSATVGPCDCQRPDMPPSIDLKEFMEV----EEGTNVNIVAKIKGVPFPTLTWFK-- 16152
Query: 879 AP----------LDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
AP L + V+ D + Q+ RSD+G Y ++ + +R+
Sbjct: 16153 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 16212
Query: 929 VVEKAGPPIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR 987
V+ + GPP+ + + V + W PKDDG S+I Y ++K + W +V +
Sbjct: 16213 VLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPK 16272
Query: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
+ T+ L+ G+EY FR+ +N G+ + TAR L
Sbjct: 16273 ECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 16313
Score = 211 bits (536), Expect = 4e-54
Identities = 160/614 (26%), Positives = 270/614 (43%), Gaps = 45/614 (7%)
Query: 431 ELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHV 489
+L++E +V + +V+ + + +S K T W K+G+ ++ + RI ++
Sbjct: 23225 DLVIEP---DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDS 23281
Query: 490 GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
L I + +D G Y G ++ I++ + K +PPK + +
Sbjct: 23282 LDLTTLSIKETHKDDGGQY-----GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVS 23336
Query: 550 SENAIV-----VVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 604
+E+ + + G + + W +V + T RT ++
Sbjct: 23337 AESITLSWNPPLYTGGCQITNYIVQKRDTTTTVW----DVVSATVARTTLK--------- 23383
Query: 605 IESAQREDEGRYTIKVTNPVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVW 659
+ + E ++ I N G+ A +V P PP T++ +D ++ W
Sbjct: 23384 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 23443
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
P+ +GG PV GY +ERK++ S W K+N + +T +++ + EGI YE RV+A N +
Sbjct: 23444 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 23503
Query: 720 GVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
GV + S N++ ++ P P P ++V+ TL+W P G I GY+VE
Sbjct: 23504 GVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKR 23560
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIA 835
W+ A+ V FTV L R FRV+ N AG S+P+ P+T ++
Sbjct: 23561 DLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEV 23620
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFD 894
E P+I + R T + GE L GKP P + W +G ++ S R ++ +DF
Sbjct: 23621 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 23680
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVEW 953
+ V+ A R D G+Y L + + ++V+++ GPP V V V + W
Sbjct: 23681 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 23740
Query: 954 QAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I Y V+K + + W V S V+ L+ GNEY FR+ N G
Sbjct: 23741 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 23800
Query: 1014 ----LSDSPGVSKN 1023
L +P + KN
Sbjct: 23801 VGEPLESAPVLMKN 23814
Score = 210 bits (535), Expect = 5e-54
Identities = 152/568 (26%), Positives = 255/568 (44%), Gaps = 40/568 (7%)
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE 527
T +WYK+ E++ + + + + ++I D + G Y S SA
Sbjct: 26903 TIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT----- 26957
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
I+V+ + K PP ++ T+E +++ PP K
Sbjct: 26958 IRVQILDKPGPPGGPIEFKTVTAEK-------------ITLLWRPPADDGGAKITHYIVE 27004
Query: 588 TEGRTRI------EKRVDCSSFVIESAQ--REDEGRYTIKVTNPVG-----EDVASIFLQ 634
+R+ E +C +I + + + +E + ++ N G E + +
Sbjct: 27005 KRETSRVVWSMVSEHLEEC---IITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKN 27061
Query: 635 VVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT 694
P PP +T + ++ +VW P+ DGG ++GY +E++ K S W K+ E
Sbjct: 27062 AFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR 27121
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDT 751
+T + T + E Y+ RV AVNA G S+PS K PI P P + + D T +
Sbjct: 27122 DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKS 27181
Query: 752 TTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLPTGARILFR 810
+ TL W P G + GY+VE EEW +T+ V + V NL G FR
Sbjct: 27182 SITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFR 27241
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VN AG+ EP + +PV ++I E P+I L LR + I K GE + +++PF+G+P P
Sbjct: 27242 VSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPP 27301
Query: 871 QVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI-ENMKDTATIRIR 928
V W K L + +R + +D ++ + Q R+D+G+Y L+++ ++T+ ++
Sbjct: 27302 TVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVK 27361
Query: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
V++ + VK V + W P DG S I+ Y ++K D W V +
Sbjct: 27362 VLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS 27421
Query: 989 TSCTVSDLIVGNEYYFRVYTENICGLSD 1016
TS + DL ++FRV EN G+ +
Sbjct: 27422 TSFKLIDLSEKTPFFFRVLAENEIGIGE 27449
Score = 209 bits (532), Expect = 1e-53
Identities = 154/579 (26%), Positives = 261/579 (45%), Gaps = 27/579 (4%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK-WYKNGVEVRPSK-RITISHVGRFHKLVIDDVRPEDE 505
+ V A E V + ++ + + W K+G E+ + R+ I + LV+ D D
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G Y LS + I V+ + + PP+ L +G T+E + A N D
Sbjct: 24777 GQYIL-----KLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL--AWNPPLQD 24829
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP-- 623
++ ++ ++ T+ T++ V ++ + +E + + N
Sbjct: 24830 GGAN-----ISHYII-EKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 24883
Query: 624 VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
+GE + S + + P PP ++++ +D ++ W P+ DGG + GY++E++ K
Sbjct: 24884 IGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK 24943
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGV---SQPSMNTKPFMPIAPT 737
RW K N + T+ T + EG YE RV A NA GV S+PS+ + + P
Sbjct: 24944 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP 25003
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-- 795
P + V D + ++ +L W P G + GY+VE ++EW T P G
Sbjct: 25004 GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTC-TPPTGLQGKQ 25062
Query: 796 FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG 855
FTV L FR+ +N G EPATL V +E EPP+I L LR+ + +
Sbjct: 25063 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 25122
Query: 856 EQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L L V +G+P P+V W K L T R + + T+ + R DSG Y L+++
Sbjct: 25123 ATLRLFVTIKGRPEPEVKWEKAEGIL-TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 25181
Query: 916 IENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ TA + +RV++ P+N+ ++EV + + W+ P DG ++I Y V+K +
Sbjct: 25182 NNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETT 25241
Query: 976 TMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
+ + T+ + +L G YYFRV N G+
Sbjct: 25242 RKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280
Score = 208 bits (529), Expect = 3e-53
Identities = 149/504 (29%), Positives = 229/504 (45%), Gaps = 42/504 (8%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE 613
I+V+ G KL + V P P +W K + ++ T + V +S R D
Sbjct: 14396 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSV-RADA 14454
Query: 614 GRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGY 673
G YTI + N +G ASI ++V+ +P P + ++ + + + L WEPP +DGG P+ Y
Sbjct: 14455 GIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHY 14514
Query: 674 LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM- 732
++ER++ G + ++ + + ++ +I Y RV AVN +G + P +
Sbjct: 14515 VLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 14573
Query: 733 --PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP 790
P P P+ + V + T T+ W+PP G I GY++E +G E W N
Sbjct: 14574 QDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL 14633
Query: 791 VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
V +T K L G FRV N AG SEP+ P + + PK+ LR +
Sbjct: 14634 VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSL 14689
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKG------------GAPLD---------------- 882
K G+++ L G P P + W K APL
Sbjct: 14690 EVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLP 14749
Query: 883 -TSRVHVRTS-DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVM 940
T R+ + S ++ VR + R D G Y + V+ ++ A + V++ GPPIN +
Sbjct: 14750 LTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV 14809
Query: 941 VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIV 998
+++ T+ L +W+ P DDG SEI+ Y ++K D K EW V RH +V+ LI
Sbjct: 14810 FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIE 14869
Query: 999 GNEYYFRVYTENICGLSDSPGVSK 1022
G EY FRV EN G P VSK
Sbjct: 14870 GKEYLFRVRAENRFG-PGPPCVSK 14892
Score = 205 bits (522), Expect = 2e-52
Identities = 154/585 (26%), Positives = 255/585 (43%), Gaps = 40/585 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E + +V + + T +W + E+ S R I + L++ D D G
Sbjct: 23635 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 23694
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A S S +N V+ + + PP+ + +G TSE
Sbjct: 23695 QYILRASNVAGSKSFPVN-----VKVLDRPGPPEGPVQVTGVTSEKC------------- 23736
Query: 567 SITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
S+T PP ++ ++ ++ T+ T + V +S + +E + I
Sbjct: 23737 SLTWSPPLQDGGSDISHYVV-EKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMA 23795
Query: 621 TNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N G E + +P PP+++ +T++ +D + W P DGG + GY+V
Sbjct: 23796 VNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV 23855
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFM 732
E++ + RW+K N T+ T + E YE RV A NA GV +PS T K
Sbjct: 23856 EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD 23915
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW---VPANTE 789
P+ P + + D T + TL W P G I GY+VE C EEW P
Sbjct: 23916 PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 23975
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
V R F + L RV +N G E ++ V + E P++ L LR+
Sbjct: 23976 RVTR--FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG 24033
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE 909
+ + G + +PF+G+P P++ W++ T +V + T + R+D+G+
Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGK 24092
Query: 910 YELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFV 969
Y L ++ + +A + ++V++ GPP N+ VKEV +A + W+ P DG +++ Y +
Sbjct: 24093 YILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 24152
Query: 970 QKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
K + + NV + TS V +L G YYFRV EN G+
Sbjct: 24153 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 24197
Score = 205 bits (521), Expect = 2e-52
Identities = 150/561 (26%), Positives = 249/561 (44%), Gaps = 34/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W K+G ++ + R+ + L I + +D G YT A + + L+ + ++
Sbjct: 24345 WVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE- 24403
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVF---- 585
K PP + V +++ D V I+ EPP +
Sbjct: 24404 ----KPGPP--------------VGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 24445
Query: 586 -TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVP 639
TTT + V ++ I + E ++ I N G+ D ++ +Q P
Sbjct: 24446 DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 24505
Query: 640 DPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYE 699
PP +TS+ +D ++ W P+ DGG + GY +E+K+K S W+KLN +T ++
Sbjct: 24506 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 24565
Query: 700 STKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
+T + EG+ YE +V A N +G+ +PS ++ F+ P P +T TLKW+
Sbjct: 24566 TTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKK 24625
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G I GY+VE W+ A+ V FTV L R FRV+ N AG
Sbjct: 24626 PAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGN 24685
Query: 820 -SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
SEP+ + +T R+ + P L + + GE L +GKP P VVW+K G
Sbjct: 24686 FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDG 24745
Query: 879 APLD--TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
L+ +R+ ++++ T V+ R+D G+Y L + + I ++V+++ GPP
Sbjct: 24746 KELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPP 24805
Query: 937 IN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+ V V + W P DG + I Y ++K + + W V + + V+
Sbjct: 24806 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTK 24865
Query: 996 LIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 24866 LLPGNEYIFRVMAVNKYGIGE 24886
Score = 204 bits (519), Expect = 4e-52
Identities = 159/589 (26%), Positives = 267/589 (45%), Gaps = 45/589 (7%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
LT+KA + V K K W K G ++RPS I+ L I +D
Sbjct: 20388 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDA 20447
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G+YT K+ +++ V VP P ++ S ++E A
Sbjct: 20448 GEYTITATN---PFGTKVEHVKVTVLDVPGPPGP---VEISNVSAEKA------------ 20489
Query: 566 VSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619
++T PP P+ +++ ++ T+ T + + + V + +E + +
Sbjct: 20490 -TLTWTPPLEDGGSPIKSYIL-EKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVS 20547
Query: 620 VTNPVG--EDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL 674
N G E V S +++VD P PPE +++V ++ A + W+ P+ DGG +TGY
Sbjct: 20548 AVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYH 20607
Query: 675 VERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-- 732
VER++K S RW++ ++ + T + EG YE RV A N G+ PS + +
Sbjct: 20608 VERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMK 20667
Query: 733 ----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
P P S P V D T + +L W P+ G I GY+VE+ G E W+ T
Sbjct: 20668 DAAYPPGPPSNPH---VTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTT 20724
Query: 789 EPVERCG-FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
R F V +L T + FR+ +N AG EPA + V I E P L LR
Sbjct: 20725 GTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAELR 20783
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDS 907
+T + + G + + VP +G+P P+V WTK L +R ++ ++ T+ + + R D+
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRYDT 20842
Query: 908 GEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGY 967
G++ ++++ K + + +RV++ GP +N+ ++ + + W P DG S I Y
Sbjct: 20843 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNY 20902
Query: 968 FVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V+K + + + + V+ L G EY+FRV EN G+ +
Sbjct: 20903 IVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 20951
Score = 203 bits (517), Expect = 7e-52
Identities = 166/605 (27%), Positives = 260/605 (42%), Gaps = 40/605 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E ++ + + T +W K E+ + R+ I L + D D G
Sbjct: 22553 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 22612
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV-----VVAGNK 561
+Y A S +N V+ + + PP+ + SG T+E + + G
Sbjct: 22613 NYILKAKNVAGERSVTVN-----VKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGS 22667
Query: 562 LRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVT 621
++ + W T ++ V S + +E + I
Sbjct: 22668 DIINYIVERRETSRLVW-------------TVVDANVQTLSCKVTKLLEGNEYTFRIMAV 22714
Query: 622 NP--VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
N VGE + S + VPD P+A +T+V +D I+VWE P DGG + GY++E
Sbjct: 22715 NKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLE 22774
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFMP 733
++ K RW + + + E T +IE YE RV A NA G+S+PS + K P
Sbjct: 22775 KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDP 22834
Query: 734 IAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP--V 791
I P + V D+T ++ L W P G I GY+VE C EW T P +
Sbjct: 22835 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMC-TPPTGI 22893
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
+ V+ L FR+ +N AG E A + P+ + E E P I L LR+
Sbjct: 22894 NKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 22953
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
+ G L L VP +G+P P+V W K + + + TS F T + R DSG+Y
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF-TSLVLDNVNRYDSGKYT 23012
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
L+++ + +A + +RV++ PP+N+ V E+ + + W+ P DG S+I Y V+K
Sbjct: 23013 LTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 23072
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
+ + V S + L G YYFRV EN G+ G+ TA +K
Sbjct: 23073 REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI----GLPAQTADPIKVA 23128
Query: 1032 ITFKP 1036
+P
Sbjct: 23129 EVPQP 23133
Score = 203 bits (516), Expect = 9e-52
Identities = 157/575 (27%), Positives = 257/575 (44%), Gaps = 39/575 (6%)
Query: 462 VSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
V D V GK W K E+ +++++ + G+ VI D G YT
Sbjct: 29066 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 29125
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
+ K + +KV LD G + + V K L S+ E
Sbjct: 29126 S---GTKAVSVMVKV------------LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA 29170
Query: 576 A-TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
T + T+ +E S+V+ + +E + ++ N G V
Sbjct: 29171 EITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP 29230
Query: 635 VV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLN 689
+V +P PP G++ I+ W P DGG ++ YLV++++K S RW ++N
Sbjct: 29231 IVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVN 29290
Query: 690 FE-VFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
+ V +T + T ++EG Y+ RV AVNA G S+PS + +P P S P
Sbjct: 29291 KDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPR- 29349
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP-VERCGFTVKNL 801
V D T + +L W P G I GY++E + +++W +T + FTV +L
Sbjct: 29350 --VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDL 29407
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G + FRV VN+ G SE + + E E P + L L++T + G L L+
Sbjct: 29408 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM 29467
Query: 862 VPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKD 921
V G+P P + W+K G L SR + T++ ++ V + R D+G+Y + + ++ K
Sbjct: 29468 VSVSGRPPPVITWSKQGIDL-ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 29526
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
+AT+ ++V + GP +V VKEV + + W+ P DG + + Y V+K + +
Sbjct: 29527 SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKT 29586
Query: 982 VYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T +S L+ G YYFRV ENI G+ +
Sbjct: 29587 VTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 29621
Score = 202 bits (515), Expect = 1e-51
Identities = 126/404 (31%), Positives = 190/404 (47%), Gaps = 12/404 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP P+ ++SV + + WE P YDGG PVTGY +E K S+RW ++N + T
Sbjct: 16316 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 16375
Query: 698 ----YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTD 750
Y+ T +IEG Y+ RV+A+NA GV S+ + P PIAP P + D T
Sbjct: 16376 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVT-DWTK 16434
Query: 751 TTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
++ L+W PP + G + GY+VEY EG EEW + V V L GA FR
Sbjct: 16435 SSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFR 16494
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VNIAG EP + + +++ P ++L +R + G + ++ GKP P
Sbjct: 16495 VRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP 16554
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
V W L + T+ + ++ RS G Y L + E + TI + V+
Sbjct: 16555 TVTWNMNERTL-PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 16613
Query: 931 EKAGP-PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
+ GP + + + + W +P+DDG S I Y ++K + W V
Sbjct: 16614 DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ 16673
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
+ TV LI G Y+FR+ EN G+ P V + A +++ IT
Sbjct: 16674 NATVQGLIQGKAYFFRIAAENSIGM--GPFVETSEALVIREPIT 16715
Score = 201 bits (510), Expect = 4e-51
Identities = 227/907 (25%), Positives = 363/907 (40%), Gaps = 108/907 (11%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V ++ E++ KWF+N + I SSKY+ L I L D A Y
Sbjct: 12650 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 12709
Query: 327 EVAVKDE-----KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKD 381
V++ + K L V+E + IV PL+D + V +V+ + W K+
Sbjct: 12710 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 12769
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEV 441
G E+ F R ++ D +H+L D D G Y V + AEL++ E E
Sbjct: 12770 GEEVP----FDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEF 12825
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
++ + D TV + AVF C++S EK KWY+NG E++ K+ G H+L+I D R
Sbjct: 12826 VEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCR 12885
Query: 502 PEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
+DE +Y V D + A+L EI VE + PP+ L+ G + + + N
Sbjct: 12886 LDDECEYACGVEDRKS---RARLFVEEIPVEII---RPPQDILEAPG---ADVVFLAELN 12936
Query: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
K +++V V ++GD+ +EG +I + C + D+G Y
Sbjct: 12937 KDKVEVQWLRNNMVV---VQGDKHQMMSEG--KIHRLQIC------DIKPRDQGEYRFIA 12985
Query: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL-VERKK 679
+ A L++ P +I + +D + D GKP+T + +
Sbjct: 12986 K----DKEARAKLELAAAP------KIKTADQDLVV--------DVGKPLTMVVPYDAYP 13027
Query: 680 KGSQRWMKLNFEVFT---ETTYEST--KMIE---GILYEMRVFAVNAIGVSQPSMNTKPF 731
K W K N + T +TT E T +++E G ++ N G ++ +N K
Sbjct: 13028 KAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVI 13087
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
P +L V + D +L W P G I GY+VE + WV A T+
Sbjct: 13088 DVPGPVR---NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLA-TDRA 13143
Query: 792 ERCGFTVKNLPT-GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
E C FTV L G LFRV N G EP PV R + P P ++ T
Sbjct: 13144 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITD 13201
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---FDTVFFVRQAARS-- 905
+ + G L P GGA + + +R +DT VR S
Sbjct: 13202 VNRFGVSLTWEPPEY----------DGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSAT 13251
Query: 906 -----DSGEYELSVQIEN-----MKDTATIRIRV---VEKAGPPINVMVKEVWGTNALVE 952
+ EY V+ +N AT ++V +E+ PP+N+ + ++ ++
Sbjct: 13252 VTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLK 13311
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P DG S I+GY +++ ++ W + + V+ L GN+Y +RV EN
Sbjct: 13312 WEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENK 13371
Query: 1012 CGLSD-SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
G+SD S + TA T +K+ + P +T L+
Sbjct: 13372 AGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPST------------ 13419
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
G+P+P W + + + L I D G YT + N +
Sbjct: 13420 --GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 13477
Query: 1131 AECKLEV 1137
E + V
Sbjct: 13478 GEIDVNV 13484
Score = 201 bits (510), Expect = 4e-51
Identities = 147/489 (30%), Positives = 221/489 (45%), Gaps = 29/489 (5%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKR 597
PP++ LD T + I V G +R+ + G P P TW K +V EKR
Sbjct: 17905 PPEVELDV---TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR-------EKR 17954
Query: 598 VDCSSFV------IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVG 651
VD + I+ A R D G+Y I N G S + V+D P P + +++T+V
Sbjct: 17955 VDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 18014
Query: 652 EDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
++ + WE P+ +GG +T ++VE +K + W + +V ++ Y
Sbjct: 18015 KENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYF 18072
Query: 712 RVFAVNAIGVSQPSMNTK-PFMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
RV A N +GV P++ TK P + I P EP +L + D T LKWR P+ G
Sbjct: 18073 RVCAENKVGVG-PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 18131
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y VE L+GS++W + ++ + V FRV N G S+ +
Sbjct: 18132 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TE 18190
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-- 885
V ++E + P + L L K G+ + L +GKP P+V WTK D +R
Sbjct: 18191 EVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 18248
Query: 886 -VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEV 944
V + T + F + +A RSD G+Y ++ A + V++K GP N+ + +V
Sbjct: 18249 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDV 18308
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
V W P+DDG EI Y ++K + K M W TV+ LI GNEY F
Sbjct: 18309 SSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIF 18368
Query: 1005 RVYTENICG 1013
RV EN G
Sbjct: 18369 RVRAENKIG 18377
Score = 200 bits (508), Expect = 7e-51
Identities = 148/582 (25%), Positives = 254/582 (43%), Gaps = 35/582 (6%)
Query: 450 VKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
VKA EQ + T W K+G ++ + R+ +S L I + ED G Y
Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 25465
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
A S++ + I LD G I V+ + ++I
Sbjct: 25466 ELCVSNSAGSITVPITI---------------IVLDRPGPPGPIRIDEVSCDS----ITI 25506
Query: 569 TGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN 622
+ PP ++ ++ + T+T + + V +S I E ++ + N
Sbjct: 25507 SWNPPEYDGGCQISNYIVEKKETTSTTWHI-VSQAVARTSIKIVRLTTGSEYQFRVCAEN 25565
Query: 623 PVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
G+ S VV P PP ++ + ++ W+ P+ DGG V GY +E
Sbjct: 25566 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 25625
Query: 678 KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPT 737
K++ S W K N + +T + + + EG++YE RV+A N G+ + S + +P P
Sbjct: 25626 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 25685
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
P V ++T + +LKW P+ G I GY+VE W+ N ++ F
Sbjct: 25686 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 25745
Query: 798 VKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGE 856
V L R FRV N A SEP+ P+ +++ EPP++ + R + K GE
Sbjct: 25746 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 25805
Query: 857 QLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L + G+P P + W K G + + +R + ++D T+ V+ R D+G+Y L+++
Sbjct: 25806 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLK 25865
Query: 916 IENMKDTATIRIRVVEKAGPPINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
+ + +V++K GPP + + + + W P++DG ++I Y V+K +
Sbjct: 25866 NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET 25925
Query: 975 KTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + TSC V+ L+ GNEY FRV N G+ +
Sbjct: 25926 SHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 25967
Score = 198 bits (504), Expect = 2e-50
Identities = 117/410 (28%), Positives = 204/410 (49%), Gaps = 22/410 (5%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTET- 696
+P PP ++ + + ++ W PP+ +GG P+TGY +E++++GS W +++ T+
Sbjct: 15598 LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 15657
Query: 697 ----TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVT 749
+ +++EG+ Y+ R A+NA G+ PS + P + PI P P V+D T
Sbjct: 15658 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 15717
Query: 750 DTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP---VERCGFTVKNLPTGAR 806
++ +L W+PP + G I GY+VE EG+ +W N EP + C V NL +
Sbjct: 15718 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVN-EPDKLITTCECVVPNLKELRK 15776
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
FRV VN AG SEP+ + +I E P++ + + + K G Q+ + +G
Sbjct: 15777 YRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG 15836
Query: 867 KPRPQVVWTKGGAPLDTSR--VH-------VRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+P P+ W G + VH + T++ +V + + RS +G+Y ++ + +
Sbjct: 15837 RPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNK 15896
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ TA R++V++ GPP ++ V ++ + + W+ P DDG I GY ++K
Sbjct: 15897 AGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK 15956
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS-PGVSKNTAR 1026
W V T+ V DL+ +Y+FRV EN G+ + + TAR
Sbjct: 15957 AWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR 16006
Score = 198 bits (503), Expect = 3e-50
Identities = 169/622 (27%), Positives = 268/622 (43%), Gaps = 40/622 (6%)
Query: 430 AELIVEEKQLEVLQDIADLT-----VKASEQAVFKCEVSDE---KVTGKWYKNGVEVRPS 481
+ +I++E Q+E D+ +T KA +S KVT W + ++ +
Sbjct: 28634 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT--WKLEEMRLKET 28691
Query: 482 KRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKI 541
R++I+ L + D D G Y L +A + + V + + P
Sbjct: 28692 DRVSITTTKDRTTLTVKDSMRGDSGRYFLT-----LENTAGVKTFSVTVVVIGRPGPVTG 28746
Query: 542 HLDCSGKTSENAIVVVAGNKLRLDVSITG------EPPPVATWLKGDEVFTTTEGRTRIE 595
++ S ++E+ ++ K IT E A L V T T +
Sbjct: 28747 PIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 28806
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
K ++ S F + S R V+ P+ E I P P + V +
Sbjct: 28807 KYMEYS-FRVSSENR-------FGVSKPL-ESAPIIAEHPFVPPSAPTRPEVYHVSANAM 28857
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WE P +DGG + GY VE+K++ + W+K N E Y+ T ++EG+ Y+ R +A
Sbjct: 28858 SIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYA 28917
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE- 774
+NA GVS+ S ++P M P P V DVT +T +L W P G + GY++E
Sbjct: 28918 LNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIER 28977
Query: 775 --YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSEPATLAQPVTI 831
G W+ N V FTV L G FRV+ N AG S+ + PVT
Sbjct: 28978 KPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTC 29037
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVR 889
R+ PPK L L + + G L L GKP P+++WTKG LD +V ++
Sbjct: 29038 RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQ 29097
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
+ ++ RSDSG+Y L+V+ + ++ ++V++ GP + V V
Sbjct: 29098 YTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKC 29157
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W P++DG +EI Y V++ + + W V S V+ LI NEY FRV
Sbjct: 29158 TLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 29217
Query: 1010 NICG----LSDSPGVSKNTARI 1027
N G + P V++N+ I
Sbjct: 29218 NKYGPGVPVESEPIVARNSFTI 29239
Score = 197 bits (501), Expect = 5e-50
Identities = 164/594 (27%), Positives = 258/594 (43%), Gaps = 46/594 (7%)
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKL 495
L+ + DL A E + F+ ++ + GK W K + R+++ L
Sbjct: 19984 LKGLPDLCYLAKENSNFRLKIP---IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 20040
Query: 496 VIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV 555
++ D + D G YT A K + IKV V K P + T+E
Sbjct: 20041 IVYDCQKSDAGKYTITLKNVA---GTKEGTISIKV--VGKPGIPTGPIKFDEVTAEA--- 20092
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKGDEVFT-TTEGRTRIEKR-VDCSSFVIESA---QR 610
+++ PP G E+ E R + + V C+S V ++ R
Sbjct: 20093 ----------MTLKWAPPKDDG---GSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 20139
Query: 611 EDEG-RYTIKVTNP----VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPP 662
EG YT +V+ VGE + S + DVPD P I V D L W P
Sbjct: 20140 LHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDP 20199
Query: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
GG P+TGY +E K++ S W + N ++ T + EG+ YE RV A+N GV
Sbjct: 20200 KKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVG 20259
Query: 723 QPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+PS+ ++P + + P P V ++T + TL W P G + GY+VE S+
Sbjct: 20260 KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS 20319
Query: 783 WVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIR 841
W+ AN V C FTV +L G + FR+ N AG S P+ + + ++ E P I
Sbjct: 20320 WMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIV 20379
Query: 842 LPRHLRQTYIRKVGEQLNL-VVPFQGKPRPQVVWTKGGAPLDTSRV-HVRTSDFDTVFFV 899
L ++ K G+ + L + GKP P+ W+K G + S + + ++ ++ +
Sbjct: 20380 LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTI 20439
Query: 900 RQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
+ A R D+GEY ++ +++ V++ GPP V + V A + W P +D
Sbjct: 20440 KYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLED 20499
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
G S I Y ++K + + W V E + + LI GNEY FRV N G
Sbjct: 20500 GGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 20553
Score = 192 bits (489), Expect = 1e-48
Identities = 116/380 (30%), Positives = 190/380 (50%), Gaps = 8/380 (2%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP A+ + V + L WEPP DGG+P+ Y++E+K++ RW+K + +
Sbjct: 14184 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 14243
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T +IEG + +V A N GV PS T+ P +P S PL L V D +
Sbjct: 14244 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 14303
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTV-KNLPTGARILFRVVGV 814
W+PP + G I GY VE C G+E+W+ N+ P++ F V + + + RV V
Sbjct: 14304 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 14363
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
N G SEP+ +++ V ++ P I L H I GE+L++ VPF+ P P V W
Sbjct: 14364 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 14420
Query: 875 TKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKA 933
K G + S R+ ++ V ++ R+D+G Y ++++ + TA+I ++V+
Sbjct: 14421 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 14480
Query: 934 GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTV 993
GP ++ ++ ++ + W+ P+ DG + I+ Y +++ + + V S TV
Sbjct: 14481 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 14540
Query: 994 SDLIVGNEYYFRVYTENICG 1013
DLI EY+FRV N G
Sbjct: 14541 KDLIPNGEYFFRVKAVNKVG 14560
Score = 191 bits (485), Expect = 3e-48
Identities = 127/440 (28%), Positives = 205/440 (46%), Gaps = 10/440 (2%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVPD 640
T+T T + V + + +E ++ IK N G D A + +++ P
Sbjct: 26612 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPG 26671
Query: 641 PPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYES 700
PP +T+V + + W P+ +GG V GY +E K + S W K N V T ++
Sbjct: 26672 PPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKV 26731
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPP 760
T + G++YE RV+A NA GV +PS ++P + I P ++ + D++ + +L W+ P
Sbjct: 26732 TTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQP 26791
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR- 819
G I GY+VE W A+ V F + L ++ FRV N G
Sbjct: 26792 AFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSI 26851
Query: 820 SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA 879
S P+ + P+T + P I LP + + G + L GKP P + W K
Sbjct: 26852 SNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDK 26911
Query: 880 PLDTSRVHV--RTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPI 937
L T+ + T+D ++ ++ A R +SG YEL ++ +ATIR+++++K GPP
Sbjct: 26912 ELQTNALVCVENTTDLASI-LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPG 26970
Query: 938 N-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ K V + W+ P DDG ++I Y V+K + + W V E T + +
Sbjct: 26971 GPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI 27030
Query: 997 IVGNEYYFRVYTENICGLSD 1016
I GNEY FRV N G+ +
Sbjct: 27031 IKGNEYIFRVRAVNKYGIGE 27050
Score = 189 bits (480), Expect = 1e-47
Identities = 117/378 (30%), Positives = 174/378 (46%), Gaps = 7/378 (1%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PD P+ + V + ++ W P D G P+ GY +E+++ S W ++N +
Sbjct: 14903 PDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKA 14961
Query: 699 ESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTL 755
++EG+ Y RV A NA G S PS PI+P P+ + D + TT L
Sbjct: 14962 NVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVT-DTSSTTIEL 15020
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W PP G G I GY V+ L G+ EW + ++ +TVK + GA RV VN
Sbjct: 15021 EWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVN 15080
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
AG P QPVT+ E EPP + L ++ G+ L + G+P P VWT
Sbjct: 15081 AAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWT 15139
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K LD RV + + ++ A R D G Y ++ A R+ V + GP
Sbjct: 15140 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGP 15199
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+++ L+ W P+DDG SEI G+ +++ D K W E R + C ++
Sbjct: 15200 VLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER-SKCDITG 15258
Query: 996 LIVGNEYYFRVYTENICG 1013
L+ G EY FRV +N G
Sbjct: 15259 LLEGQEYKFRVIAKNKFG 15276
Score = 171 bits (432), Expect = 5e-42
Identities = 168/618 (27%), Positives = 263/618 (42%), Gaps = 61/618 (9%)
Query: 429 EAELIVEEKQLEVLQDI---ADLTVKASEQAVFKCEVS---DEKVTGKWYKNGVEVRPSK 482
E + + ++ E+ D+ A LTVKA + V+ + K+T W K + ++ K
Sbjct: 13678 EIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDK 13735
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
RITI +V + + I D + D G Y A+++ + + ++V + K PP
Sbjct: 13736 RITIENVPKKSTVTIVDSKRSDTGTYII----EAVNVCGRATAV-VEVNVLDKPGPPAA- 13789
Query: 543 LDCSGKTSENAIVV------VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
D + T+E+ ++ G+K+ + + W K T + + K
Sbjct: 13790 FDITDVTNESCLLTWNPPRDDGGSKI-TNYVVERRATDSEVWHKLSS--TVKDTNFKATK 13846
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ A G V PV + Q D P PP + + + +D
Sbjct: 13847 LIPNKEYIFRVAAENMYG-----VGEPVQASPITAKYQ-FDPPGPPTRLEPSDITKDAVT 13900
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W P DGG P+TGY VER + +W++ N +TTY + Y RV A
Sbjct: 13901 LTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAE 13960
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G +PS +T+P + PI P P V+DV T+ L W P G I+ Y++
Sbjct: 13961 NLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVI 14020
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E G++EWV E V + L G FRV VN AG SEP+ + PV RE
Sbjct: 14021 EMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCRE 14079
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKP------RPQVVWTKGGAPLDT-- 883
PP PR L I K L VP + G P + V KG +DT
Sbjct: 14080 KLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTV 14137
Query: 884 --SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRVVEKAGPPIN 938
++ V +++ R AA + G+ + + +IE+ KDT T GPP
Sbjct: 14138 KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYT-EIEDSVLAKDTFT-------TPGPPYA 14189
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT--VSDL 996
+ V +V + ++W+ PK+DG I Y ++K ++ W + C V+D+
Sbjct: 14190 LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKA-GKTAGPDCNFRVTDV 14248
Query: 997 IVGNEYYFRVYTENICGL 1014
I G E F+V EN G+
Sbjct: 14249 IEGTEVQFQVRAENEAGV 14266
Score = 169 bits (427), Expect = 2e-41
Identities = 134/515 (26%), Positives = 221/515 (42%), Gaps = 40/515 (7%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
+ +++ D+T K E A C++ + KWY+ G E+ S++ +S GR H L +
Sbjct: 30535 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 30594
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
EDEG YT + + L Q P+ H G + G
Sbjct: 30595 EEQEDEGVYTCIATNEVGEVETSSKLL--------LQATPQFH---PGYPLKEKYYGAVG 30643
Query: 560 NKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE-GRYTI 618
+ LRL V G P P TW G ++ +E T IE + V+++ QR+ G+Y +
Sbjct: 30644 STLRLHVMYIGRPVPAMTWFHGQKLLQNSENIT-IENTEHYTHLVMKNVQRKTHAGKYKV 30702
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
+++N G A + +++ D PD P + I ++ ++ A++ W+PP DGG +T Y+VE+
Sbjct: 30703 QLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 30762
Query: 678 -KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP----------SM 726
+ K W ++ + + TT + E Y RV A N G+S P S
Sbjct: 30763 CEAKEGAEWQLVSSAI-SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 30821
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
KP P PT + VT + + W+PP G I Y +E + +W+
Sbjct: 30822 FEKPGAPGKPT-------ITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISV 30874
Query: 787 NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHL 846
TE + F+VKNL G FRV N+ G SE + +++P+T + L
Sbjct: 30875 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 30934
Query: 847 RQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF---FVRQAA 903
R +R LV G P+P V W + G + + R +F + +
Sbjct: 30935 RNLNVR-YQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVT 30993
Query: 904 RSDSGEYELSV--QIENMKDTATIRIRVVEKAGPP 936
D+ Y++ Q ++ TA++ + V K P
Sbjct: 30994 DDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP 31028
Score = 157 bits (396), Expect = 7e-38
Identities = 142/552 (25%), Positives = 234/552 (42%), Gaps = 90/552 (16%)
Query: 28 KEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIK 87
K+ PA AP A + F+ +P S+ V A +AKV G +P+ +K
Sbjct: 8436 KDKPAVAPAT------KKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPN---VK 8486
Query: 88 WFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSC 147
W KGKW +L G R + + A +L I D G YR C +
Sbjct: 8487 WTKGKWRQLNQ--GGRVFIHQKGDEA------KLEIRDTTKTDSGLYR--------CVAF 8530
Query: 148 GFNIDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDD 207
+ ++E S +L+ +R ++K E D +LKK ++ KK ++++
Sbjct: 8531 NEHGEIE------SNVNLQVDERKKQEKI----EGDLRAMLKKTPIL----KKGAGEEEE 8576
Query: 208 LGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKV------------EVKKS 255
+ +I ELLK EYEK A YGITD RG+L+ + K E+++S
Sbjct: 8577 I----DIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERS 8632
Query: 256 AAFTKKLDPAYQV------------------------DRGNKIKLMVEISDPDLTLKWFK 291
K+ + D ++ ++I+ P++ L W+K
Sbjct: 8633 ERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYK 8692
Query: 292 NGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTP 351
++++PS K+ G + L + C L D Y + +L V EP
Sbjct: 8693 GTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEPAW--ERH 8750
Query: 352 LEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDV 411
L+D + G M + S + W ++G L + R++ + + K H L +DV
Sbjct: 8751 LQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQ----GRHKTEVEHKVHKLTIADV 8806
Query: 412 VQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKW 471
ED+G+Y + AEL +E + ++ + I ++ V + A F+CEVS + W
Sbjct: 8807 RAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTW 8866
Query: 472 YKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV----PDGYALSLS-AKLNFL 526
YK E+ S++ + GR H + I +V P+DEG Y+ + P G A S + L
Sbjct: 8867 YKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTK 8926
Query: 527 EIKVEYVPKQEP 538
EIK+E P P
Sbjct: 8927 EIKLELKPPDIP 8938
Score = 156 bits (395), Expect = 9e-38
Identities = 95/314 (30%), Positives = 153/314 (48%), Gaps = 13/314 (4%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V + + PP+I L + K+ + V AG + LD ++ G+P P +W K + E
Sbjct: 19284 VTILAENVPPRIDLSVAMKS---LLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE 19340
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
G +R C + + S R+D G YTI N G A+I L+V+D P PP +V+I
Sbjct: 19341 GIKMAMQRNLC-TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINK 19399
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ D A+L WEPP+ DGG +T Y+V++++ W +++ V T+ K+IEG Y
Sbjct: 19400 MYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEY 19458
Query: 710 EMRVFAVNAIGV-----SQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
+ R+ A N GV ++P++ P+ P P ++ ++T T+ W+PP G
Sbjct: 19459 QFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP---VISNITKDHMTVSWKPPADDG 19515
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I GYL+E + W N +P+ L G FRV +N AG +P+
Sbjct: 19516 GSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 19575
Query: 825 LAQPVTIREIAEPP 838
++ R+ PP
Sbjct: 19576 ASKAAYARDPQYPP 19589
Score = 154 bits (388), Expect = 6e-37
Identities = 199/903 (22%), Positives = 340/903 (37%), Gaps = 94/903 (10%)
Query: 274 IKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE 333
I V ++ ++ KW KNG EIK + K L I D A Y
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045
Query: 334 KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKA 393
L+V+ + ++D +V R EVSE V WMKD EL D
Sbjct: 3046 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITD---- 3101
Query: 394 RYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKAS 453
R + +K+ H L+ D G+Y V+ G A+L VE + + + ++ V
Sbjct: 3102 RIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3161
Query: 454 EQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFV 511
++AV + EV+++ V WYK+G+E+ + +V R H++ I + R D G+YTFV
Sbjct: 3162 QRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV 3221
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
S++ YV EPP++ + + V +G R I+G
Sbjct: 3222 AGRNRSSVTL----------YVNAPEPPQVLQEL------QPVTVQSGKPARFCAVISGR 3265
Query: 572 PPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASI 631
P P +W K +++ +T + + + +IE A ED YT + N G S
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE-AFPEDAAVYTCEAKNDYGVATTSA 3324
Query: 632 FLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKP-------------VTGYLVERK 678
L V+VP+ + V I + + G+P V+ Y ++K
Sbjct: 3325 SLS-VEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK 3383
Query: 679 KKGSQRWMKLNFE-VFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPT 737
K S+ + FE + E+ EG A NA+G + N P +
Sbjct: 3384 IKPSRFFRMTQFEDTYQLEIAEAYPEDEG---TYTFVASNAVGQVSSTANLSLEAPESIL 3440
Query: 738 SEPLHLIVEDVTDTTTTLKWR-PPNRIGAGGIDGYLVEYCLEGSE--EWVPANTEPVE-- 792
E + +E +K + P + G + + E + +W A E E
Sbjct: 3441 HERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESD 3500
Query: 793 RCGFTVKNLPTGARILFRVV------GVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHL 846
+C + IL V + + +T+ E P + P+ L
Sbjct: 3501 KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSL 3560
Query: 847 RQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDT--VFFVRQAAR 904
VG+ + G P + +W K GA L S + R SD + + +
Sbjct: 3561 TTF----VGKAAKFICTVTGTPVIETIWQKDGAALSPS-PNWRISDAENKHILELSNLTI 3615
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEI 964
D G Y + D + +++K +KE+ + + N ++
Sbjct: 3616 QDRGVYSCKASNKFGADICQAELIIIDKPH-----FIKELEPVQSAI---------NKKV 3661
Query: 965 -MGYFVQKADKKTMEWFNVYER---NRHTSCTVSDLIVGNEYYFRVYTEN---ICGLSDS 1017
+ V + K T+ W ++ + D I E ++ +C S+
Sbjct: 3662 HLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNE 3721
Query: 1018 PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKP 1077
G S +A + + P K+ D P +L ++ G SA L+C ++G P
Sbjct: 3722 AGSSSCSATVT---VREPPSFVKKVD----PSYL-------MLPGESARLHCKLKGSPVI 3767
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+V W KN E+ E + L+I D+G+Y+C AVN++G ++ +
Sbjct: 3768 QVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 3827
Query: 1138 RVP 1140
+ P
Sbjct: 3828 KEP 3830
Score = 154 bits (388), Expect = 6e-37
Identities = 221/934 (23%), Positives = 348/934 (37%), Gaps = 146/934 (15%)
Query: 271 GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV 330
G + + E++ + ++W +N + K+ + GK L I D Y
Sbjct: 12926 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 12985
Query: 331 KDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSE-EGAQVMWMKDGVELTRE- 388
KD++ +L + P I T +D V VG + M V A+ W K+ L+ +
Sbjct: 12986 KDKEARAKLELAAAPK-IKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT 13044
Query: 389 -DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
D+ + F+ + + D+GRY+++ +AE + K ++V + +
Sbjct: 13045 IDTTAEQTSFR---------ILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRN 13095
Query: 448 LTVKASEQAVFKCEVS---DEKVT---GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
L V + F EVS +E +T K VE R KR T ++ D
Sbjct: 13096 LEVTET----FDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTW--------VLATDRA 13143
Query: 502 PEDEGDYTFVPDG---YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA 558
E T + G Y +SA+ + + D G I V
Sbjct: 13144 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN 13203
Query: 559 GNKLRLDVSITGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
R VS+T EPP + ++ T+ T + R + S +
Sbjct: 13204 ----RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQ 13259
Query: 613 EGRYTIKVTNPVG---EDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDG 666
E + ++ N +G A+ F++V D P PP + + + L WEPP+ DG
Sbjct: 13260 EYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDG 13319
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSM 726
G P+ GY++ER ++G W++ N ++ E TY+ T + +G Y RV A N GVS PS
Sbjct: 13320 GSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 13379
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
P EP D++ L+ PN I VP+
Sbjct: 13380 ILGPLTADDAFVEP----TMDLSAFKDGLEVIVPNPITI-----------------LVPS 13418
Query: 787 N--TEPVERCGFTVKNLPTGARILFRVVG------VNIAGRSEPA-----------TLAQ 827
P F K L TG R+ + + ++ + RS+ T++
Sbjct: 13419 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 13478
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD----- 882
+ + IA P P+ L+ I K L P GG+PL
Sbjct: 13479 EIDVNVIARPSA---PKELKFGDITKDSVHLTWEPPDDD----------GGSPLTGYVVE 13525
Query: 883 ----TSRVHVRTSDFDT-------------VFFVRQAARSDSGEYELSVQIE--NMKDTA 923
+ + + DF T + + AR+ G E + E NM A
Sbjct: 13526 KREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPA 13585
Query: 924 TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
T+ PP NV ++ + + W PK+DG S I GY V++ + + +W
Sbjct: 13586 TV-------PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 13638
Query: 984 ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
E T V+ L G Y +RV N G S S+ T I P +
Sbjct: 13639 EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRPTEEIQAVDTQEAP------E 13689
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+ K L L V AG L V G P+PK+ W K M +++D + I N
Sbjct: 13690 IFLDVKLLAGL---TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 13746
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
T+ I D GTY AVN G A A ++ V
Sbjct: 13747 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 152 bits (385), Expect = 1e-36
Identities = 103/305 (33%), Positives = 150/305 (49%), Gaps = 8/305 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
E P I LD T ++ + + AG+ + L+ +SI G+P P ++W K + ++ T+I
Sbjct: 20374 EAPTIVLD---PTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSD-ITQIT 20429
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S I+ A R+D G YTI TNP G V + + V+DVP PP V I++V + A
Sbjct: 20430 STPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKA 20489
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L W PP+ DGG P+ Y++E+++ W ++ E + +TK+I+G Y RV A
Sbjct: 20490 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQGNEYIFRVSA 20548
Query: 716 VNAIGVSQP--SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
VN G +P S K P P V +VT T T+ W+ P G I GY V
Sbjct: 20549 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 20608
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E + S WV A PV V L G+ FRV N AG P+ + V +++
Sbjct: 20609 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 20668
Query: 834 IAEPP 838
A PP
Sbjct: 20669 AAYPP 20673
Score = 150 bits (378), Expect = 9e-36
Identities = 188/818 (22%), Positives = 320/818 (39%), Gaps = 114/818 (13%)
Query: 277 MVEISDPDLTLKWFK----NGQEI-------KPSSKYVFENVGKKRI----LTINKCTLA 321
++ IS +TL+W K G+EI + S ++ K+RI TI A
Sbjct: 30439 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 30498
Query: 322 DDAAYEVAVKDEKCF-----------TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-V 369
+ + V ++E T+L E P I ++D +G+ +++ + V
Sbjct: 30499 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKEMKDVTTKLGEAAQLSCQIV 30557
Query: 370 SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCE 429
+ W + G EL + +Y+ DG+ H L QED G Y I E
Sbjct: 30558 GRPLPDIKWYRFGKELIQS----RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 30613
Query: 430 AE-----LIVEEKQLEVLQDIADLTVKA--SEQAVFKCEVSDEKVTGKWYKNGVEVRPSK 482
E L+ Q + + A S + + W+ ++ S+
Sbjct: 30614 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 30673
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
ITI + + LV+ +V+ + Y + LS ++ ++ + +P K
Sbjct: 30674 NITIENTEHYTHLVMKNVQRKTHAGK------YKVQLSNVFGTVDAILDVEIQDKPDK-- 30725
Query: 543 LDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKGDEVFTTTEGRTRIEKRVDC 600
IV+ A L+ I+ +PP +W+ + V E + E ++
Sbjct: 30726 -------PTGPIVIEA--LLKNSAVISWKPPADDGGSWIT-NYVVEKCEAKEGAEWQLVS 30775
Query: 601 SSFVIESAQ----REDEGRY-------TIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
S+ + + + E+ G Y T +++P+ I + P P IT+
Sbjct: 30776 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 30835
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
V +D ++ W+PP DGG + Y +E+++K +W+ + E ET + +IEG+ Y
Sbjct: 30836 VTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEY 30895
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPT--------SEPLHLIVEDVTDTTTTLK----- 756
E RV N G S+ S ++P P + E +L V ++ T K
Sbjct: 30896 EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHP 30955
Query: 757 ------WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
+R I A G+ Y ++ G + + A+ + + V+ G +
Sbjct: 30956 KPIVKWYRQGKEIIADGLK-YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSV--- 31011
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV--GEQLNLVVPFQGKP 868
S A+L E+ P KI LP+ L GE +++ +PF GKP
Sbjct: 31012 ---------SGTASL-------EVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 31055
Query: 869 RPQVVWTKGGAPLDTSRVH--VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
P + W KG +D + + + T F ++ F R D+G Y + + D T+
Sbjct: 31056 DPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE 31115
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
+ V + PP V V +V + + W P DG S+I Y V+K W V +
Sbjct: 31116 LDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA- 31174
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNT 1024
R T TV +L Y FRV EN GLS S+ T
Sbjct: 31175 RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 31212
Score = 149 bits (375), Expect = 2e-35
Identities = 110/360 (30%), Positives = 159/360 (44%), Gaps = 37/360 (10%)
Query: 268 VDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYE 327
V G E+S D+ ++W+ G++++PS K V + GK LT+ L D +
Sbjct: 12207 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 12266
Query: 328 VAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTR 387
+ KD K LFVKEPPV PLEDQ V G + EVS E A+V W K+G E+ +
Sbjct: 12267 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 12326
Query: 388 EDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
+Y DG+ L+ D ED Y + L V +E L+ + D
Sbjct: 12327 ----SKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTD 12382
Query: 448 LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGD 507
L V+ E A F+CE+S E KW+K+G E++ K+ I G LVI+ +DE +
Sbjct: 12383 LQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAE 12442
Query: 508 YTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVS 567
Y+ + S L LE + + + + SE + KL +VS
Sbjct: 12443 YSC--EVRTARTSGMLTVLEEEAVFTKNL--------ANIEVSETDTI-----KLVCEVS 12487
Query: 568 ITGEPPPVATWLKGDEVF-------TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
+P W KGDE TEGR RI VI++A ED G Y ++
Sbjct: 12488 ---KPGAEVIWYKGDEEIIETGRYEILTEGRKRI--------LVIQNAHLEDAGNYNCRL 12536
Score = 149 bits (375), Expect = 2e-35
Identities = 101/318 (31%), Positives = 146/318 (45%), Gaps = 14/318 (4%)
Query: 528 IKVEYVPKQEP---PKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKG-DE 583
+K E V +E P + L SG + V AG+ +RL+ + G+P P W K D
Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSG-----VLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDA 18241
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
T R +I+ R D S F + A+R D G+Y + TN G VA + V+D P P
Sbjct: 18242 TDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVR 18301
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++I V D + W+PP DGG + Y++E+ + W + V T T T++
Sbjct: 18302 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT-TVTRL 18360
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT---TTLKWRPP 760
IEG Y RV A N IG P+ +KP + +P +VT + T+ W PP
Sbjct: 18361 IEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPP 18419
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS 820
G I GY +E + S WVP N + V+NL FRV N G
Sbjct: 18420 EYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIG 18479
Query: 821 EPATLAQPVTIREIAEPP 838
EP+ ++PV ++ EPP
Sbjct: 18480 EPSLPSRPVVAKDPIEPP 18497
Score = 145 bits (366), Expect = 2e-34
Identities = 135/522 (25%), Positives = 214/522 (40%), Gaps = 46/522 (8%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP + VG+ L W P +DGG + Y++E K G+ W+++ V T
Sbjct: 13981 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPT- 14039
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTT 752
T + ++EG Y RV AVN G S+PS + P + + P S P L V ++T T
Sbjct: 14040 TQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 14099
Query: 753 TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVV 812
LKW P + G I Y+VE + W +T V+ TV L G+ +FRV
Sbjct: 14100 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVA 14158
Query: 813 GVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKPRP 870
N G+S+ + V ++ P P L + K L P G+P
Sbjct: 14159 AENAIGQSDYTEIEDSVLAKDTFTTPGP--PYALAVVDVTKRHVDLKWEPPKNDGGRPIQ 14216
Query: 871 QVV----------WTKGG---APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ V W K G P RV + F VR + G +I
Sbjct: 14217 RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 14276
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+++D + PP+++ V + + + W+ P+ +G S I+GY V+ T
Sbjct: 14277 SIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTE 14329
Query: 978 EWFNVYERN-RHTSCTVSDLIVGN-EYYFRVYTENICGLSDSPGVSKNTARILKTGITFK 1035
+W V R + V + +V + EY RV N G+S+ +S+N + K
Sbjct: 14330 KWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV--VAKDPDCKP 14387
Query: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
+ + HD +V+ G ++ R P P V W K+ E++ +
Sbjct: 14388 TIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14434
Query: 1096 ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N L + + DAG YT N+LG A A ++V
Sbjct: 14435 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 144 bits (363), Expect = 5e-34
Identities = 255/1152 (22%), Positives = 411/1152 (35%), Gaps = 191/1152 (16%)
Query: 54 FLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESH--N 111
FL +P S++ GK A + V G P I+ + K GA S + +
Sbjct: 3553 FLSRPKSLTTFVGKAAKFICTVTGT-----PVIE-------TIWQKDGAALSPSPNWRIS 3600
Query: 112 SASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFN-IDVEAPRQDASGQSLESFKR 170
A N + +EL + + DRG Y + K D C I ++ P + LE +
Sbjct: 3601 DAENKHILEL--SNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFI---KELEPVQS 3655
Query: 171 TSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIA 230
KK ++D E+ K D +PP +Y KI
Sbjct: 3656 AINKKVHLECQVD-----------EDRKVTVTWSKDGQKLPPG----------KDY-KIC 3693
Query: 231 FQYGITDLRGMLKRLK------------------KAKVEVKKSAAFTKKLDPAYQVDRGN 272
F+ I L L +LK A V V++ +F KK+DP+Y + G
Sbjct: 3694 FEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGE 3753
Query: 273 KIKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV-AV 330
+L ++ P + + WFKN +E+ S+ V + IL I + D +Y AV
Sbjct: 3754 SARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAV 3813
Query: 331 KD---EKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGA-QVMWMKDGVELT 386
D + C TE+ +KEPP I T LE + G + EVS G ++ W KD ++
Sbjct: 3814 NDVGSDSCSTEIVIKEPPSFIKT-LEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIR 3872
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG----QCEAELIVEEKQLEVL 442
++ F + + IFS D G Y+ + C A +++E V
Sbjct: 3873 SSKKYRL---FSQKSLVCLEIFS-FNSADVGEYECVVANEVGKCGCMATHLLKEPPTFV- 3927
Query: 443 QDIADLTVKASEQAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
+ + DL + + V E ++ W K +R +I +S L+I DV+
Sbjct: 3928 KKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQ 3987
Query: 502 PEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNK 561
G YT + + A S + V + +EP KI I V AG+
Sbjct: 3988 ISFGGKYTCLAENEAGS--------QTSVGELIVKEPAKI------IERAELIQVTAGDP 4033
Query: 562 LRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVT 621
L+ ++ G P W K ++ + RI + + + SA+ D G+YT +++
Sbjct: 4034 ATLEYTVAGTPELKPKWYKDGRPLVASK-KYRISFKNNVAQLKFYSAELHDSGQYTFEIS 4092
Query: 622 NPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL-VERKKK 680
N VG V+D P + P+ + V G ++ K
Sbjct: 4093 NEVGSSSCETTFTVLDRDIAP---------------FFTKPLRNVDSVVNGTCRLDCKIA 4137
Query: 681 GS----QRWMKLNFEVFTETTY-----ESTKMIEGILYEMR------VFAVNAIGVSQ-- 723
GS W K E+ Y E T +E I +M A N++G
Sbjct: 4138 GSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS 4197
Query: 724 --------PSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY 775
PS TKP + L T T++W N+ G Y+ +
Sbjct: 4198 GALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKE 4257
Query: 776 CLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIA 835
LE S E T V N+ G S + +P T E
Sbjct: 4258 ALESSLELYLVKTSDSGTYTCKVSNVAGGVEC------------SANLFVKEPATFVEKL 4305
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDT 895
EP + + K G+ L G P ++ W + S H R S ++
Sbjct: 4306 EP-----------SQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKH-RMSFVES 4353
Query: 896 VFFVR--QAARSDSGEYELSVQIENMKDTATIRIRVVE-----KAGPPINVMVKEVWGTN 948
+R DSGEY Q E D + + V E K PI V+ +
Sbjct: 4354 TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLL 4413
Query: 949 ALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYT 1008
A V P + + +F ++ + + ++ S + + + ++
Sbjct: 4414 AEVAGTPPFE------ITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQ--- 4464
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALN 1068
C +++ G S +AR+ R P F+ + + G +AA
Sbjct: 4465 ---CRVTNEVGSSICSARV---------------TLREPPSFIKKIESTSSLRGGTAAFQ 4506
Query: 1069 CAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
++G V W+K+ EI ED +T V +L + G Y C+A N+ G
Sbjct: 4507 ATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGI 4566
Query: 1129 ALAECKLEVRVP 1140
L V+ P
Sbjct: 4567 QRCSALLSVKEP 4578
Score = 139 bits (351), Expect = 1e-32
Identities = 217/918 (23%), Positives = 355/918 (38%), Gaps = 100/918 (10%)
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEIS-DPDLTLKWFKNGQEIKPSSKYVFEN 306
A++ V++ F KKL+P+ V + + +I P++ + W+K+ EI+ SSK+
Sbjct: 7297 AQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 7356
Query: 307 VGKKRILTINKCTLADDAAYEV----AVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDR 362
V +L ++ ++ D Y A T L VKEPP+ P + G
Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKP-HPIETLKGAD 7415
Query: 363 VEMAVEVSEEGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
V + E+ V W KD EL +Y+ + + +V D G YQ
Sbjct: 7416 VHLECELQGTPPFHVSWYKDKRELRSGK----KYKIMSENFLTSIHILNVDAADIGEYQC 7471
Query: 422 -ITN--GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSD-EKVTGKWYKN-GV 476
TN G I + ++ ++D++ ++ + + E ++ W+K+ G
Sbjct: 7472 KATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGE 7531
Query: 477 EVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT--FVPDGYALSLSAKLNFLEIKVEYVP 534
VR S I IS+ L V P + G YT D A L+ LE V
Sbjct: 7532 IVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE-PATIVE 7590
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E +I V G+ L+ ++ G P W K D T++ + +I
Sbjct: 7591 KPE---------------SIKVTTGDTCTLECTVAGTPELSTKWFK-DGKELTSDNKYKI 7634
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSV--GE 652
S I + D G Y+ +V NPVG+D + LQV D PP R G
Sbjct: 7635 SFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGL 7694
Query: 653 DWAILVWEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNFEVFTETTYESTKMIE-GILYE 710
+ +V E +Y G P++ + E + S R K + T + M+E +
Sbjct: 7695 SGSSVVMECKVY-GSPPISVSWFHEGNEISSGR--KYQTTLTDNTCALTVNMLEESDSGD 7751
Query: 711 MRVFAVNAIGVSQPS--MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
A N G + S + + +P+ ++ T+ +K PP +
Sbjct: 7752 YTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVS---- 7807
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-----SEPA 823
+GS E VP +RC ++++ + A + V + +G S A
Sbjct: 7808 -------WFKGSSELVPG-----DRCNVSLED--SVAELELFDVDTSQSGEYTCIVSNEA 7853
Query: 824 TLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDT 883
A T I P K + L I K G+ L L F G P V W K G +
Sbjct: 7854 GKASCTTHLYIKAPAKF--VKRLNDYSIEK-GKPLILEGTFTGTPPISVTWKKNGINVTP 7910
Query: 884 S-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVM-- 940
S R ++ T++ + + + D+G+Y ++ + KD+ + +I ++E PP V
Sbjct: 7911 SQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE---PPYFVKQL 7967
Query: 941 --VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIV 998
VK G +A ++ Q G EI G K D K R+ T +V
Sbjct: 7968 EPVKVSVGDSASLQCQLA---GTPEI-GVSWYKGDTKLRPTTTYKMHFRNNVAT----LV 8019
Query: 999 GNEYYFRVYTENICGLSDSPG-VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDR 1057
N+ E IC +S G VS +T ++ + ++ P F L D
Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQ-------------EQKLPPSFSRQLRDV 8066
Query: 1058 VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGT 1117
G +CA+ G V W K+ +++ P + TLNI + AG
Sbjct: 8067 QETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQ 8126
Query: 1118 YTCRAVNELGEALAECKL 1135
Y+C A N +G A + +L
Sbjct: 8127 YSCTATNPIGSASSSARL 8144
Score = 137 bits (345), Expect = 6e-32
Identities = 141/569 (24%), Positives = 234/569 (41%), Gaps = 50/569 (8%)
Query: 68 DAVVVAKVNGKELPDKPTIKWFKGKWL----ELGSKSG--ARFSFKESHNSASNVY---T 118
+ V A+V GK+ + + + K++ + K G A F + SH V+
Sbjct: 11551 EGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKND 11610
Query: 119 VELHIGKVVL--GDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKS 176
+LH + VL + ++LE+K D V+ A + LE+ + K
Sbjct: 11611 AKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLH 11670
Query: 177 D-TAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGI 235
D TA E D L K EV ++ K KD +++ P+ G ++ K A
Sbjct: 11671 DKTAVEKDEITL--KCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKA----- 11723
Query: 236 TDLRGMLKRL-----KKAKVEVKKSAAFTKKLDPAYQVDR--GNKIKLMVEISDPDLTLK 288
DL+ + + K K V A K P Y V+ G +E+S+PD+ +
Sbjct: 11724 -DLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ 11782
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLI 348
W GQ + S GKK IL ++ C L + K L VKE P++
Sbjct: 11783 WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIF 11842
Query: 349 VTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIF 408
+TPL D +VF D + EVS E W+K E+T +D R+ KDG +H ++
Sbjct: 11843 ITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDD----RFELIKDGTKHSMVI 11898
Query: 409 SDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVT 468
ED +Y +LI+E +L+ L + D+T K E AVF E+S + +
Sbjct: 11899 KSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIR 11958
Query: 469 GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEI 528
KW+KN + ++ +++ G+ H + D+ +D + +S AKL LE
Sbjct: 11959 VKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRV--EAMGMSSEAKLTVLEG 12016
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+ K + D +G + I L I+ PV + G E+ +
Sbjct: 12017 DPYFTGKLQ------DYTGVEKDEVI---------LQCEISKADAPVKWFKDGKEIKPSK 12061
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYT 617
+ + + +++ A + D G+YT
Sbjct: 12062 NAVIKADGKK--RMLILKKALKSDIGQYT 12088
Score = 136 bits (342), Expect = 1e-31
Identities = 97/354 (27%), Positives = 155/354 (43%), Gaps = 30/354 (8%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ IVV AG L+ I G+P P W K + T R I+ + ++ V++ R
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKP 669
D G+Y +K++N G I ++V+D P PPE +++T V + L W PP+ DGG
Sbjct: 24774 TDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGAN 24833
Query: 670 VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMN-- 727
++ Y++E+++ W +++ EV Y+ TK++ G Y RV AVN G+ +P +
Sbjct: 24834 ISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGP 24892
Query: 728 ---TKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
P+ P P S P V +T + + W P G I+GY++E + W
Sbjct: 24893 VTACNPYKPPGPPSTPE---VSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 24949
Query: 785 PANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N + + V L G FRV N AG EP+ + + PP
Sbjct: 24950 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP------ 25003
Query: 845 HLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVRTSDFD 894
G N V + + W+K GGAP+ V V+ + D
Sbjct: 25004 ----------GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 25047
Score = 134 bits (338), Expect = 4e-31
Identities = 206/946 (21%), Positives = 358/946 (37%), Gaps = 124/946 (13%)
Query: 232 QYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEIS-DPDLTLKWF 290
QY + K + A++ VK+ F KKL+ + +G I+L +IS P++ + WF
Sbjct: 6340 QYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWF 6399
Query: 291 KNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY----EVAVKDEKCFTELFVKEPPV 346
+N E+ S KY + +LTIN+ + D Y V D C T L VK PPV
Sbjct: 6400 RNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPV 6459
Query: 347 LIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHI 405
P G V + E+S +V+W+KD ++ FK + D HI
Sbjct: 6460 FTQKP-SPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSK-HFDTSLHI 6517
Query: 406 LIFSDVVQEDRGRY------QVITNGGQCEAELIVEEKQLEVLQDIADLTVKASE-QAVF 458
L ++ D G Y +V ++ C + + ++ L D + L A E +A+
Sbjct: 6518 L---NLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIV 6574
Query: 459 KCEVSDEKVTGKWYKN-GVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY--TFVPDGY 515
+ + ++ W K+ G +R S+ IS + L + + G Y D
Sbjct: 6575 E---GFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAG 6631
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
SA L LE + K EP + V GN L+ +TG P
Sbjct: 6632 MRECSAVLTVLE-PARIIEKPEP---------------MTVTTGNPFALECVVTGTPELS 6675
Query: 576 ATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
A W K G E+ ++ +V +S I A+ D+G Y+ +V N VG+ ++ +
Sbjct: 6676 AKWFKDGRELSADSKHHITFINKV--ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVH 6733
Query: 635 VVDVPDPPEAVR-ITSVGEDWAILVWEPPMYDGGKPVT-GYLVERKK--KGSQRWMKLNF 690
V D PP +R + V V G P++ G+ + + G + +
Sbjct: 6734 VSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSE 6793
Query: 691 EVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPS--MNTKPFMPIAPTSEPLHLIVEDV 748
V T GI A N G + S + + T + + ++
Sbjct: 6794 NVCTLNLSLLEPSDTGI---YTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMS 6850
Query: 749 TDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARIL 808
T+ ++ PP ++ +GS E VP E C ++++ T +
Sbjct: 6851 LTFTSVIRGTPPFKV-----------KWFKGSRELVPG-----ESCNISLEDFVTELELF 6894
Query: 809 ---------FRVVGVNIAGRSEPAT---LAQPVT-IREIAEPPKIRLPRHLRQTYIRKVG 855
+ + N AG + T + +P T ++ +A+ + + G
Sbjct: 6895 EVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLAD-------------FSVETG 6941
Query: 856 EQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSV 914
+ L + G P V W K + S R + ++ T+ + ++ D +Y +
Sbjct: 6942 SPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLI 7001
Query: 915 QIENMKDTATIRIRVVEKAGPPINV----MVKEVWGTNALVEWQAPKDDGNSEI-MGYFV 969
+ E +D + V+E PP + V+ V G A ++ K DG EI + ++
Sbjct: 7002 ENEAGQDICEALVSVLE---PPYFIEPLEHVEAVIGEPATLQC---KVDGTPEIRISWYK 7055
Query: 970 QKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILK 1029
+ ++ + + +N S ++ + + + +N G S V AR
Sbjct: 7056 EHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR--- 7112
Query: 1030 TGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR 1089
++ P F L D G+ A C + G +V W K+ + ++
Sbjct: 7113 ---------------KLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLK 7157
Query: 1090 EDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
+D + V TL I + G Y C A N LG A + KL
Sbjct: 7158 DDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 7203
Score = 134 bits (338), Expect = 4e-31
Identities = 118/428 (27%), Positives = 186/428 (43%), Gaps = 39/428 (9%)
Query: 430 AELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKW----YKNGVEV-RPSKRI 484
+E +V + + V + DL VK EV+ VT W Y G E+
Sbjct: 16705 SEALVIREPITVPERPEDLEVK---------EVTKNTVTLTWNPPKYDGGSEIINYVLES 16755
Query: 485 TISHVGRFHKLVIDD-------VRPEDEGD-YTFVPDGYALSLSAKLNFLEIKVEYVPKQ 536
+ +FHK+ D+ V+ EGD Y + + K +F + +
Sbjct: 16756 RLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDEL 16815
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
PP +HLD K + + G L +G+P P +W K DE + RT I+
Sbjct: 16816 APPTLHLDFRDK-----LTIRVGEAFALTGRYSGKPKPKVSWFK-DEADVLEDDRTHIKT 16869
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWA 655
+ A+R D G+Y + V N G + VVD P PP V V +D+
Sbjct: 16870 TPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM 16929
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
++ W+PP+ DGG +T Y++E+K+ G WM + +TT + +K++EG Y R+ A
Sbjct: 16930 VISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT-SASAKTTCKVSKLLEGKDYIFRIHA 16988
Query: 716 VNAIGVSQP----SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
N G+S P SM K + P IV +VT + + W P+ G I Y
Sbjct: 16989 ENLYGISDPLVSDSMKAKDRFRV--PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNY 17045
Query: 772 LVEYCLEGSEEWVPANTEPVE-RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
++E S+ W +P+ F V +L G + FRV N G +P+ ++PV
Sbjct: 17046 ILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVF 17105
Query: 831 IRE-IAEP 837
++ IA+P
Sbjct: 17106 AKDPIAKP 17113
Score = 134 bits (336), Expect = 6e-31
Identities = 205/931 (22%), Positives = 351/931 (37%), Gaps = 127/931 (13%)
Query: 249 KVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENV 307
+++VK+ F ++L P +V + + ++L E++ P + W KN +EI+ S KY +
Sbjct: 4948 ELKVKEPPTFIRELKPV-EVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDR 5006
Query: 308 GKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKEPPVLIVTPLEDQQVFVGDRV 363
L I KC +D Y+ V +E C T + +KEPP I V
Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSAT 5066
Query: 364 EMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY--QV 421
+ + W+KD L +D+ + D + I S V GRY Q
Sbjct: 5067 FQSTVAGSPPISITWLKDDQILDEDDNVYISF---VDSVATLQIRS-VDNGHSGRYTCQA 5122
Query: 422 ITNGG--QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEV 478
G +C A L+V+E ++++ + V + +C V+ ++ KW K+G ++
Sbjct: 5123 KNESGVERCYAFLLVQEPA-QIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQI 5181
Query: 479 RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEP 538
PS+ ++S I V +D G YTF + S S +L + + +P
Sbjct: 5182 VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDA-YLRVLDQNIPPSFT 5240
Query: 539 PKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKR 597
K+ + V G+ + ++ ++G P A W K G E+ T+ + R +R
Sbjct: 5241 KKL----------TKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHER 5290
Query: 598 VDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPD----PPEAVRI-TSVGE 652
S + + + ED YT KV+N G+D S L V + P P I S E
Sbjct: 5291 --SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVE 5348
Query: 653 DWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMR 712
AIL PP +W K + E+ + + +EG +
Sbjct: 5349 FKAILKGTPPF------------------KIKWFKDDVELVSGP--KCFIGLEGSTSFLN 5388
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+++V+A Q + + + S L+ VT+ +K ++I G D
Sbjct: 5389 LYSVDASKTGQYTCHVT--NDVGSDSCTTMLL---VTEPPKFVKKLEASKIVKAG-DSSR 5442
Query: 773 VEYCLEGSEE----WVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPA 823
+E + GS E W E + + + + A I + +G PA
Sbjct: 5443 LECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPA 5502
Query: 824 TLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDT 883
T + EPP + +T +++L G P +VVW K L +
Sbjct: 5503 GSTSCSTKVIVKEPPVFSSFPPIVETL---KNAEVSLECELSGTPPFEVVWYKDKRQLRS 5559
Query: 884 SRVH-VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK---------- 932
S+ + + + +F T + SD GEY Q E DT +++ E
Sbjct: 5560 SKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSL 5619
Query: 933 ---AGPPINVMVKEVWGTNALVEWQAPKDD---GNSEIMGYFVQKADKKTMEWFNVYERN 986
AG P + V+W K++ + I FV+ T+++ N
Sbjct: 5620 TVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENV--ATLQFAKAEPAN 5677
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+Y IC + + G+ +N A ++ +P E M
Sbjct: 5678 ------------AGKY--------ICQIKNDGGMRENMATLM----VLEPAVIVEKAGPM 5713
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
V G + L C V G P+ V W K+ + K + Y + +L
Sbjct: 5714 -----------TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLR 5762
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
I DAGTYT + N +G++ ++V
Sbjct: 5763 ILSVERQDAGTYTFQVQNNVGKSSCTAVVDV 5793
Score = 133 bits (335), Expect = 8e-31
Identities = 218/947 (23%), Positives = 367/947 (38%), Gaps = 154/947 (16%)
Query: 250 VEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVG 308
++VK+ F KK P + +G + L E+ P + W+K+ +E++ KY +
Sbjct: 7393 LKVKEPPIFRKKPHPIETL-KGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSEN 7451
Query: 309 KKRILTINKCTLADDAAYEVA----VKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVE 364
+ I AD Y+ V + C + +K PP V L D VG V+
Sbjct: 7452 FLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP-RFVKKLSDISTVVGKEVQ 7510
Query: 365 MAVEVSEEGAQ---VMWMKDGVELTRE-DSFKARYRFKKDGKRHILIFSDVVQEDRGRY- 419
+ + EGA+ V+W KD E+ RE D+ Y L FS V + G+Y
Sbjct: 7511 LQTTI--EGAEPISVVWFKDKGEIVRESDNIWISY----SENIATLQFSRVEPANAGKYT 7564
Query: 420 -QVITNGG--QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNG 475
Q+ + G +C A L V E +++ + V + +C V+ +++ KW+K+G
Sbjct: 7565 CQIKNDAGMQECFATLSVLEPAT-IVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDG 7623
Query: 476 VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPK 535
E+ + IS + L I +V P D G Y+F S + L++ VP
Sbjct: 7624 KELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTAS-LQVSDRTVPP 7682
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWL-KGDEVFTTTEGRTRI 594
K+ + +G ++G+ + ++ + G PP +W +G+E+ + + +T +
Sbjct: 7683 SFTRKLK-ETNG---------LSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL 7732
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV------VDVPDPPEAVRIT 648
+ + + D G YT TN G D S L V V PDP + +T
Sbjct: 7733 TDNT--CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDV--LT 7788
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
+ +V P + S W K + E+ + +E +
Sbjct: 7789 GTNVTFTSIVKGTPPF-----------------SVSWFKGSSELVPGDRCNVS--LEDSV 7829
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDV--TDTTTTLKWRPPNRIGAG 766
E+ +F V+ + + E ++ + TT L + P +
Sbjct: 7830 AELELFDVDT----------------SQSGEYTCIVSNEAGKASCTTHLYIKAPAKF-VK 7872
Query: 767 GIDGYLVE----YCLEGSEEWVPA----------NTEPVERCGFTVKNLPTGARILFRVV 812
++ Y +E LEG+ P N P +RC T I V
Sbjct: 7873 RLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTV 7932
Query: 813 G---------VNIAGRSEPAT----LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLN 859
N +G+ + L P ++++ EP K+ VG+ +
Sbjct: 7933 EDAGQYNCYIENASGKDSCSAQILILEPPYFVKQL-EPVKV------------SVGDSAS 7979
Query: 860 LVVPFQGKPRPQVVWTKGGA---PLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI 916
L G P V W KG P T ++H R + VF Q +DSGEY +
Sbjct: 7980 LQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF--NQVDINDSGEYICKAEN 8037
Query: 917 ENMKDTATIRIRVVEKAGPP-INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ +A+ + V E+ PP + +++V T L G SE + K K
Sbjct: 8038 SVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISG-SEPISVSWYKDGKP 8096
Query: 976 TMEWFNVYERNRHTSCTVS----DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
+ NV + T++ D + +Y C ++ G + ++AR++ T
Sbjct: 8097 LKDSPNVQTSFLDNTATLNIFKTDRSLAGQYS--------CTATNPIGSASSSARLILTE 8148
Query: 1032 ITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED 1091
PF D R+AP +D VV G SA C V G KV W K+ EIR
Sbjct: 8149 GKNPPF----FDIRLAP------VDAVV--GESADFECHVTGTQPIKVSWAKDSREIRSG 8196
Query: 1092 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
K+ I+ + L + + D+G YTC AVNE+G+ +L ++
Sbjct: 8197 GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIK 8243
Score = 130 bits (328), Expect = 5e-30
Identities = 235/1144 (20%), Positives = 415/1144 (36%), Gaps = 170/1144 (14%)
Query: 54 FLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSA 113
F KK + G + KV+G LP + +WFK G S +
Sbjct: 5239 FTKKLTKMDKVLGSSIHMECKVSGS-LPI--SAQWFK---------DGKEISTSAKYRLV 5286
Query: 114 SNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSE 173
+ +V L + + L D Y +V D+C + V+ P +
Sbjct: 5287 CHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPS--------FLVKPGR 5338
Query: 174 KKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKK-----SEYEK 228
+++ ++F +LK K K KDD +L P+ + L+G+ S
Sbjct: 5339 QQAIPDSTVEFKAILKGTPPF---KIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDAS 5395
Query: 229 IAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEIS-DPDLTL 287
QY + + V + F KKL+ + V G+ +L +I+ P++ +
Sbjct: 5396 KTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRV 5455
Query: 288 KWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKE 343
WF+N E+ S KY + ++ +N + D + ++ C T++ VKE
Sbjct: 5456 VWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 5515
Query: 344 PPVLIVTPLEDQQVFVGDRVEMAVEVSEEGA---QVMWMKDGVELTREDSFKARYRFKKD 400
PPV P + + E+++E G +V+W KD +L +K +
Sbjct: 5516 PPVFSSFPPIVETL---KNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHT 5572
Query: 401 GKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKC 460
+ + + + E + Q C + ++E + + LTV A E A +
Sbjct: 5573 SIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP-RFVSKLNSLTVVAGEPAELQA 5631
Query: 461 EVSD-EKVTGKWYKNGVEV-RPSKRITISHVGRFHKLVIDDVRPEDEGDYT--FVPDGYA 516
+ + + +W K EV R S+ I I+ V L P + G Y DG
Sbjct: 5632 SIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGM 5691
Query: 517 LSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVA 576
A L LE P + ++ +G + V G L+ + G P
Sbjct: 5692 RENMATLMVLE-----------PAVIVEKAGP-----MTVTVGETCTLECKVAGTPELSV 5735
Query: 577 TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVV 636
W K ++ T+++ + + SS I S +R+D G YT +V N VG+ + + V
Sbjct: 5736 EWYKDGKLLTSSQ-KHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVS 5794
Query: 637 DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTET 696
D PP R GG ++E K GS +
Sbjct: 5795 DRAVPPSFTRRLK--------------NTGGVLGASCILECKVAGSS-------PISVAW 5833
Query: 697 TYESTKMIEGILYE------MRVFAVNAIGVSQPSMNTKPFMPIAPTS------------ 738
+E TK++ G Y+ + +N++ S T +A +
Sbjct: 5834 FHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 5893
Query: 739 ------EPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
EPL ++ T+ ++ PP ++ G+ E V +
Sbjct: 5894 SFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVN-----------WFRGARELVKG-----D 5937
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGR-----SEPATLAQPVTIREIAEPPKI--RLPRH 845
RC ++ T A + + ++ +G S A A T + EP RL H
Sbjct: 5938 RCNIYFED--TVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH 5995
Query: 846 LRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAAR 904
+ G+ + L + G V W K G + TS + ++ T++ + + + +
Sbjct: 5996 SVEP-----GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTK 6050
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEI 964
D+G+Y ++ E +D + +E PP V E+ A V G+S
Sbjct: 6051 RDAGQYSCEIENEAGRDVCGALVSTLE---PP--YFVTELEPLEAAV--------GDSVS 6097
Query: 965 MGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC-------GLSDS 1017
+ V + T+ W+ + R T Y +T N+ ++DS
Sbjct: 6098 LQCQVAGTPEITVSWYKGDTKLRPT-----------PEYRTYFTNNVATLVFNKVNINDS 6146
Query: 1018 PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKP 1077
+ + T + F +E ++ P F L D G L C + G
Sbjct: 6147 GEYTCKAENSIGTASSKTVFRIQER--QLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI 6204
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+V W ++ + +R+D + V TL I + +G Y+C A N LG A + +L
Sbjct: 6205 QVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTA 6264
Query: 1138 RVPQ 1141
R P+
Sbjct: 6265 REPK 6268
Score = 130 bits (326), Expect = 9e-30
Identities = 119/457 (26%), Positives = 183/457 (40%), Gaps = 38/457 (8%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K G ++ SKR I+ +LVI + D G Y V + K +++++
Sbjct: 30169 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN---KCGKKAVYIKVR 30223
Query: 530 VEYVPKQEPPKIHLDC----SGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
V P + D S + S G + L + P A W
Sbjct: 30224 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI-LGYILERREVPKAAWYT----- 30277
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN------PVGEDVASIFLQVVDVP 639
I+ RV +S V++ + E + + N P+ + ++ P
Sbjct: 30278 --------IDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP 30329
Query: 640 DPPE-AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
+PP + V + L W P DGG VTGY +ERK+ + +W++ N T T Y
Sbjct: 30330 EPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 30389
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T ++ Y+ R+ A N +G+S+ S ++P + P S+P L + ++ + TL
Sbjct: 30390 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTL 30449
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W P G I GY VEY G W +N E ++ FT+ L FRV N
Sbjct: 30450 QWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAEN 30509
Query: 816 IAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
G S P A + T E P IR + K+GE L G+P P + W
Sbjct: 30510 ETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTKLGEAAQLSCQIVGRPLPDIKW 30566
Query: 875 TKGGAPLDTSRVHVRTSDFDT-VFFVRQAARSDSGEY 910
+ G L SR + +SD T V + D G Y
Sbjct: 30567 YRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 30603
Score = 129 bits (324), Expect = 2e-29
Identities = 234/1084 (21%), Positives = 390/1084 (35%), Gaps = 139/1084 (12%)
Query: 85 TIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTC 144
+I+WFK E+ + +FSF ++ T L I ++ D G Y K
Sbjct: 4705 SIQWFKDDQ-EISASEKYKFSFHDN--------TAFLEISQLEGTDSGTYTCSATNKAGH 4755
Query: 145 DSCGFNIDVEAPR---QDASGQSLESFKRTSEKKS-DTAGELDFSGLLKKREVVEEEKKK 200
+ C ++ V+ P + Q + R K + +E+ +
Sbjct: 4756 NQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARS 4815
Query: 201 KKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTK 260
KDD + L AK ++ Q + KA + VK+ F K
Sbjct: 4816 VWKDDTSTSLE------LFAAKATDSGTYICQLS----NDVGTATSKATLFVKEPPQFIK 4865
Query: 261 KLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCT 319
K P + G +I+ P + + W+ +G EI K+ + I+
Sbjct: 4866 KPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGAR 4925
Query: 320 LADDAAYEVAVKDE----KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGA- 374
+ + Y +++ C EL VKEPP I L+ +V VE+ EV+
Sbjct: 4926 VENSGTYVCEARNDAGTASCSIELKVKEPPTFI-RELKPVEVVKYSDVELECEVTGTPPF 4984
Query: 375 QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITN--GGQCEAEL 432
+V W+K+ E+ + R L + D G YQ I + GG C
Sbjct: 4985 EVTWLKNNREIRSSKKYTLTDRVSVFN----LHITKCDPSDTGEYQCIVSNEGGSCSCST 5040
Query: 433 IVEEKQL-EVLQDIADLTVKASEQAVFKCEVSDEK-VTGKWYKNGVEVRPSKRITISHVG 490
V K+ ++ I + T A F+ V+ ++ W K+ + + IS V
Sbjct: 5041 RVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVD 5100
Query: 491 RFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTS 550
L I V G YT + + +E ++ QEP +I
Sbjct: 5101 SVATLQIRSVDNGHSGRYT--------CQAKNESGVERCYAFLLVQEPAQI------VEK 5146
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQ 609
++ V + + L+ + G P WLK G ++ + E V +SF I+S
Sbjct: 5147 AKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNV--ASFRIQSVM 5204
Query: 610 REDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE-AVRITSVGEDWAILVWEPPMYDGGK 668
++D G+YT KV N G +L+V+D PP ++T + + + G
Sbjct: 5205 KQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSL 5264
Query: 669 PVTGYLVERKKKGSQRWMKLNFEVFTETTY-----ESTKMIEGILYEMRVFAVNAIGVSQ 723
P+ S +W K E+ T Y E + +E E+ A VS
Sbjct: 5265 PI-----------SAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSN 5313
Query: 724 PSMNTKPFMPIAPTSEPLHLIV-----EDVTDTT----TTLKWRPPNRIGAGGIDGYLVE 774
+ I EP +V + + D+T LK PP +I D LV
Sbjct: 5314 VA-GDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVS 5372
Query: 775 -----YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
LEGS ++ + + G ++ N G S+ T
Sbjct: 5373 GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHV------------TNDVG-SDSCT----- 5414
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHV 888
T+ + EPPK + L + I K G+ L G P +VVW + L S + +
Sbjct: 5415 TMLLVTEPPK--FVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRM 5472
Query: 889 RTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE----KAGPPINVMVKEV 944
D V + + DSG++ Q + + ++ V E + PPI +K
Sbjct: 5473 TFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLK-- 5530
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
NA V + + ++ K ++ + + + +N HTS + ++ + +
Sbjct: 5531 ---NAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEY 5587
Query: 1005 RVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYS 1064
+N G K + P+F++ L VVAG
Sbjct: 5588 HCKAQNEVGSDTCVCTVK---------------------LKEPPRFVSKLNSLTVVAGEP 5626
Query: 1065 AALNCAVRGHPKPKVVWMKNKME-IREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAV 1123
A L ++ G V W+K K E IRE IT + V TL + P +AG Y C+
Sbjct: 5627 AELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIK 5686
Query: 1124 NELG 1127
N+ G
Sbjct: 5687 NDGG 5690
Score = 126 bits (316), Expect = 1e-28
Identities = 97/360 (26%), Positives = 157/360 (43%), Gaps = 24/360 (6%)
Query: 258 FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINK 317
FT KL V++ +++ L EIS D +KWFK+G+EIKPS V + GKKR+L + K
Sbjct: 12020 FTGKLQDYTGVEK-DEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKK 12078
Query: 318 CTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM 377
+D Y +K +L +++ + +V PL +V + E+SE+
Sbjct: 12079 ALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHAN 12138
Query: 378 WMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
W G L + + K++GK H L+ + + G + A L V+ +
Sbjct: 12139 WKLKGEALLQTPDCE----IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPR 12194
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVI 497
+ +L+ + D+TV A E A F CE+S E + +WY G ++ PS ++ G+ H L +
Sbjct: 12195 VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTL 12254
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
DV+ ED G+ + A L E VE+ E + E A V
Sbjct: 12255 RDVKLEDAGEVQLTAKDF--KTHANLFVKEPPVEFTKPLEDQTV--------EEGATAV- 12303
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
L+ ++ E V + G E+ + + + RV VI ED YT
Sbjct: 12304 ------LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRV--RKLVIHDCTPEDIKTYT 12355
Score = 126 bits (316), Expect = 1e-28
Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 33/335 (9%)
Query: 526 LEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
L + V + PP I L S + + I V AG + + +TG P P W K + V
Sbjct: 15382 LPLNVVIQDDEVPPTIKLRLSVRG--DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVI 15439
Query: 586 T--------TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVD 637
T E +R E + + S I A RED+G YT+ +N +G ++ ++V D
Sbjct: 15440 EKPTDALQITKEEVSRSEAKTELS---IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYD 15496
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
P PP + +T + + L W+ P+ +GG +T Y+++++ + K +E T T
Sbjct: 15497 RPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRK---KAEWEEVTNTA 15553
Query: 698 YEST----KMIEGILYEMRVFAVNAIGVSQPSMNTK-----PFMPIAPTSEPLHLIVEDV 748
E K+I YE RV AVN G+S + K P+ P +P L
Sbjct: 15554 VEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---R 15610
Query: 749 TDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-----FTVKNLPT 803
T + + W PP G I GY +E EGS W + P+ + G F V L
Sbjct: 15611 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 15670
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
G + FR + +N AG P+ + P + PP
Sbjct: 15671 GVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPP 15705
Score = 124 bits (310), Expect = 7e-28
Identities = 245/1141 (21%), Positives = 401/1141 (35%), Gaps = 147/1141 (12%)
Query: 54 FLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSA 113
F+KK +S GK+ + + G E ++ WFK K + S+ E
Sbjct: 7494 FVKKLSDISTVVGKEVQLQTTIEGAE---PISVVWFKDKGEIVRESDNIWISYSE----- 7545
Query: 114 SNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSE 173
N+ T L +V + G Y ++K C + V P + ES K T+
Sbjct: 7546 -NIAT--LQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV--EKPESIKVTTG 7600
Query: 174 K----KSDTAG--ELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYE 227
+ AG EL +E+ + K K + G LK + +
Sbjct: 7601 DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG--------LKIINVAPSD 7652
Query: 228 KIAFQYGITDLRGMLKRLKKAKVEVKKSA---AFTKKLDPAYQVDRGNKIKLMVEISDPD 284
+ + + + G K A ++V +FT+KL + + + P
Sbjct: 7653 SGVYSFEVQNPVG--KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPP 7710
Query: 285 LTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKD----EKCFTELF 340
+++ WF G EI KY LT+N +D Y + ++C L
Sbjct: 7711 ISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLT 7770
Query: 341 VKEPPVLIVTPLEDQQVFVGDRVEM-AVEVSEEGAQVMWMKDGVELTREDSFKARYRFKK 399
V+EPP + P + V G V ++ V W K EL D +
Sbjct: 7771 VREPPSFVQKP-DPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL---E 7826
Query: 400 DGKRHILIFSDVVQEDRGRYQVITNG----GQCEAELIVEEKQLEVLQDIADLTVKASEQ 455
D + +F DV G Y I + C L ++ + ++ + D +++ +
Sbjct: 7827 DSVAELELF-DVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA-KFVKRLNDYSIEKGKP 7884
Query: 456 AVFKCEVSDEK-VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDG 514
+ + + ++ W KNG+ V PS+R I+ + L I ED G Y +
Sbjct: 7885 LILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIEN 7944
Query: 515 YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPP 574
+ S L ++ Y KQ P + V G+ L + G P
Sbjct: 7945 ASGKDSCSAQILILEPPYFVKQLEP--------------VKVSVGDSASLQCQLAGTPEI 7990
Query: 575 VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
+W KGD T ++ R + ++ V D G Y K N VGE AS FL
Sbjct: 7991 GVSWYKGDTKLRPTT-TYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 8049
Query: 635 VVDVPDPPEAVR-ITSVGEDWAILVWEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNFEV 692
V + PP R + V E + V G +P++ + + K ++ +F
Sbjct: 8050 VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLD 8109
Query: 693 FTETT--YESTKMIEGILYEMRVFAVNAIGVSQPSMN-------TKPFMPIAPTSEPLHL 743
T T +++ + + G + A N IG + S PF I P+
Sbjct: 8110 NTATLNIFKTDRSLAG---QYSCTATNPIGSASSSARLILTEGKNPPFFDIRLA--PVDA 8164
Query: 744 IVEDVTD----TTTT----LKWRPPNR-IGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
+V + D T T + W +R I +GG Y + Y LE S
Sbjct: 8165 VVGESADFECHVTGTQPIKVSWAKDSREIRSGG--KYQISY-LENSAH------------ 8209
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV 854
TV + G + VN G+ + + I+E PP + L +T
Sbjct: 8210 -LTVLKVDKGDSGQYTCYAVNEVGKD---SCTAQLNIKERLIPPSFT--KRLSETVEETE 8263
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
G L G V W K + TS + + V VR+A +D+G Y
Sbjct: 8264 GNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCK 8323
Query: 914 VQIENMKDTATIRIRVVEKAGPPI------NVMVKE---------VWGTNAL-VEWQAPK 957
V + T I + E PP+ V V E V G+ + ++W
Sbjct: 8324 VSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAG 8383
Query: 958 DDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS 1017
+ F + +E +V + + + + G++ T++ + D
Sbjct: 8384 REIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDT-----TKSKVTIKDK 8438
Query: 1018 PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKP 1077
P V+ T + G F F P+ + VV +A V G P P
Sbjct: 8439 PAVAPATKKAAVDGRLF---------FVSEPQSIR------VVEKTTATFIAKVGGDPIP 8483
Query: 1078 KVVWMKNKM-EIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
V W K K ++ + + I L IR + D+G Y C A NE GE + L+
Sbjct: 8484 NVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQ 8543
Query: 1137 V 1137
V
Sbjct: 8544 V 8544
Score = 124 bits (310), Expect = 7e-28
Identities = 96/374 (25%), Positives = 160/374 (42%), Gaps = 24/374 (6%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
QV + E+S + +KWFK+G EIK KY + G RIL INKC L D+A Y
Sbjct: 12384 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 12443
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
V+ + L V E + L + +V D +++ EVS+ GA+V+W K E+
Sbjct: 12444 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 12503
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
RY +G++ IL+ + ED G Y + + ++ V E E +
Sbjct: 12504 E----TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQ 12559
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+L + E+A F C +S E +W ++ + + + G+ LV+ D +D G
Sbjct: 12560 NLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMG 12619
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y + A +A L +E VP ++ + E VV +V
Sbjct: 12620 TYVVMVG--AARAAAHLTVIEKLRIVVPLKDT---------RVKEQQEVV-----FNCEV 12663
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
+ G A W + +E + ++K + + I A +D+ Y + +TN GE
Sbjct: 12664 NTEGAK---AKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQANYNVSLTNHRGE 12719
Query: 627 DVASIFLQVVDVPD 640
+V S +V+ D
Sbjct: 12720 NVKSAANLIVEEED 12733
Score = 123 bits (309), Expect = 9e-28
Identities = 99/374 (26%), Positives = 159/374 (42%), Gaps = 25/374 (6%)
Query: 250 VEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGK 309
V+ K+ FT++L ++ E S+P + +KW+K+G E+ KY + K
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRK 2227
Query: 310 KRILTINKCTLADDAAYE-VAVKDE--KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366
L+I +D Y V V+DE K +L V+ V V L+D +V E+
Sbjct: 2228 VHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELE 2287
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
VS E + W + VEL +Y R L DV +ED+G Y + +G
Sbjct: 2288 CIVSPENIEGKWYHNDVELKSN----GKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2343
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
+ +L ++ + + +LQ ++D V + + +VS E V G W K+G EV+PS R+ I
Sbjct: 2344 KTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI 2403
Query: 487 SHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCS 546
+ H L+I+D+ ED G+Y+F LS S +++ + V
Sbjct: 2404 VIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV---------------- 2447
Query: 547 GKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIE 606
T + V+ G K L+ ++ W DE + I K VI
Sbjct: 2448 -ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK-QRLVIN 2505
Query: 607 SAQREDEGRYTIKV 620
DEG Y + V
Sbjct: 2506 RTHASDEGPYKLIV 2519
Score = 121 bits (303), Expect = 4e-27
Identities = 99/330 (30%), Positives = 138/330 (41%), Gaps = 46/330 (13%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR------------------- 593
++ V G+++ LD SI+G P P TW+K + V E + R
Sbjct: 14688 SLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFV 14747
Query: 594 --IEKRVDC-------SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP-- 642
+ +R+ S + + R D G Y IKV N G A + V+D P PP
Sbjct: 14748 LPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN 14807
Query: 643 ---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER--KKKGSQRWMKLNFEVFTETT 697
E +R TSV + WEPP+ DGG + Y +E+ K K W+ +
Sbjct: 14808 FVFEDIRKTSV-----LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCK 14861
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTT 754
Y TK+IEG Y RV A N G P + +KP + P P P IVEDVT +
Sbjct: 14862 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDKPIVEDVTSNSML 14920
Query: 755 LKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGV 814
+KW P G+ I GY +E S W N + V L G +FRV
Sbjct: 14921 VKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAE 14979
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N AG + + + P T + PP +PR
Sbjct: 14980 NAAGPGKFSPPSDPKTAHDPISPPGPPIPR 15009
Score = 120 bits (302), Expect = 6e-27
Identities = 88/295 (29%), Positives = 136/295 (46%), Gaps = 15/295 (5%)
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
AG ++L I+G+P P W K D+ T +E D +S +I+ A R + G Y
Sbjct: 26886 AGTSVKLRAGISGKPAPTIEWYKDDKELQTN-ALVCVENTTDLASILIKDADRLNSGCYE 26944
Query: 618 IKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
+K+ N +G A+I +Q++D P PP + +V + L+W PP DGG +T Y+VE
Sbjct: 26945 LKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE 27004
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP-----SMNTKPF 731
+++ W ++ E E +TK+I+G Y RV AVN G+ +P + F
Sbjct: 27005 KRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAF 27063
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
+ P P V +T + T+ W P G I GY +E + S W E +
Sbjct: 27064 VTPGPPGIP---EVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 27120
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGR---SEPATLAQPVTIREIAEPP-KIRL 842
V L + +RV VN AG+ SEP+ + + PP KIR+
Sbjct: 27121 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRI 27175
Score = 120 bits (300), Expect = 1e-26
Identities = 87/326 (26%), Positives = 140/326 (42%), Gaps = 29/326 (8%)
Query: 523 LNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGD 582
L+ + K +VP P ++ + +G+ A AG+KLR +T
Sbjct: 29740 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT------------- 29786
Query: 583 EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+E + I D G YT+++ N G +I + ++D P PP
Sbjct: 29787 -----------VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPP 29835
Query: 643 EA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
++I + + WEPP DGG P++GY+VE++ W+ ++ E T +T++ T
Sbjct: 29836 TGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVS-ESVTRSTFKFT 29894
Query: 702 KMIEGILYEMRVFAVNAIGVSQ--PSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
++ EG Y RV A N G+ S + I P L + DV+ TL W P
Sbjct: 29895 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 29954
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G + GY+VE ++ WV N PV + L G RV +N G
Sbjct: 29955 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 30014
Query: 820 SEPATLAQPVTIRE-IAEPPKIRLPR 844
+P+ ++P+ + IA P K + PR
Sbjct: 30015 GKPSRPSKPIVAMDPIAPPGKPQNPR 30040
Score = 119 bits (298), Expect = 2e-26
Identities = 167/744 (22%), Positives = 290/744 (38%), Gaps = 123/744 (16%)
Query: 252 VKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKK 310
+K A F K+L+ Y +++G + L + P +++ W KNG + PS + K
Sbjct: 7864 IKAPAKFVKRLND-YSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKS 7922
Query: 311 RILTINKCTLADDAAYEVAVKD----EKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366
IL I T+ D Y +++ + C ++ + EPP V LE +V VGD +
Sbjct: 7923 AILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYF-VKQLEPVKVSVGDSASLQ 7981
Query: 367 VEVS---EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY--QV 421
+++ E G V W K +L ++K +R L+F+ V D G Y +
Sbjct: 7982 CQLAGTPEIG--VSWYKGDTKLRPTTTYKMHFR----NNVATLVFNQVDINDSGEYICKA 8035
Query: 422 ITNGGQCEAE--LIVEEKQL--EVLQDIADLTVKASEQAVFKCEVS-DEKVTGKWYKNGV 476
+ G+ A L V+E++L + + D+ VF C +S E ++ WYK+G
Sbjct: 8036 ENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK 8095
Query: 477 EVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV---PDGYALSLSAKLNFLEIKVEYV 533
++ S + S + L I G Y+ P G A S SA+L E K
Sbjct: 8096 PLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASS-SARLILTEGK---- 8150
Query: 534 PKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR 593
PP + + + V G + +TG P +W K D + G+ +
Sbjct: 8151 ---NPPFFDIRLA------PVDAVVGESADFECHVTGTQPIKVSWAK-DSREIRSGGKYQ 8200
Query: 594 IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE-AVRITSVGE 652
I + + + + D G+YT N VG+D + L + + PP R++ E
Sbjct: 8201 ISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVE 8260
Query: 653 DWAILVWEPPMYDGGKPVTGYLVERKKKGSQ----RWMKLNFEVFTETTYESTKMIEGIL 708
+ + +E + GSQ W K N E+ + E T ++
Sbjct: 8261 E--------------TEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 8306
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
++R +N G+ ++ + +S +++++ + P + G
Sbjct: 8307 LQVRKAGMNDAGLYTCKVSNDAGSALCTSS----IVIKEPKKPPVFDQHLTPVTVSEG-- 8360
Query: 769 DGYLVEYC-LEGSE----EWVPANTE--PVERCGFTVKNLPTGARIL------------F 809
Y+ C ++GSE +W+ A E P +RC F + +G +L +
Sbjct: 8361 -EYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSF---SFASGTAVLELRDVAKADSGDY 8416
Query: 810 RVVGVNIAGRSEPATLAQPVTIRE-------------------IAEPPKIRLPRHLRQTY 850
N+AG T VTI++ ++EP IR+ T+
Sbjct: 8417 VCKASNVAGSD---TTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATF 8473
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKG--GAPLDTSRVHVRTSDFDTVFFVRQAARSDSG 908
I KVG G P P V WTKG RV + + +R ++DSG
Sbjct: 8474 IAKVG----------GDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSG 8523
Query: 909 EYELSVQIENMKDTATIRIRVVEK 932
Y E+ + + + ++V E+
Sbjct: 8524 LYRCVAFNEHGEIESNVNLQVDER 8547
Score = 117 bits (294), Expect = 5e-26
Identities = 129/529 (24%), Positives = 197/529 (37%), Gaps = 82/529 (15%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
V +P PP +I G+ + W P++DGG P+TGY VE KK W K + +
Sbjct: 26081 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRG 26139
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLH---------LIVE 746
T Y + + G Y RV +VN +G S PS ++ P + EPL LIV+
Sbjct: 26140 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 26199
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+ +R G V L W +T+ R + T
Sbjct: 26200 AGASFTMTVPFR-----------GRPVPNVL-----WSKPDTDLRTRAYVDTTDSRTSLT 26243
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
I A R++ +TI+ + + L + T G N+ V
Sbjct: 26244 I-------ENANRNDSGKYT--LTIQNVLSAASLTLVVKVLDT----PGPPTNITVQDVT 26290
Query: 867 KPRPQVVW----TKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
K + W GGAP+ + R + V LS ++ N+++
Sbjct: 26291 KESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCN------RLSYKVTNLQEG 26344
Query: 923 ATIRIRV--------------------VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
A RV EK PP + V + + + W P+ DG S
Sbjct: 26345 AIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGS 26404
Query: 963 EIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
I+ Y V+ +K W + T VS L +EY+FRV+ EN GLSD
Sbjct: 26405 RIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEYFFRVFAENQAGLSDP----- 26458
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+L + + E E D + P V AG + ++ + G P PKV
Sbjct: 26459 --RELLLPVLIKEQLEPPEIDMKNFPSHTV-----YVRAGSNLKVDIPISGKPLPKVTLS 26511
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALA 1131
++ + ++ +F LT+N++ DAG Y A N G A
Sbjct: 26512 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 26560
Score = 117 bits (293), Expect = 6e-26
Identities = 120/486 (24%), Positives = 203/486 (41%), Gaps = 48/486 (9%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E+S ++ W KNG EI+ S K+ GK L I + D A Y +++
Sbjct: 2904 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSAT 2963
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
L V P++I + L+D D + V V+ EG W+K+GVE+ D K + R K
Sbjct: 2964 LTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTD--KCQMRTK 3019
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
K H L +V D Y + A L VE + +E + I D+ V ++A+F
Sbjct: 3020 K--LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3077
Query: 459 KCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALS 518
+CEVS+ +T +W K+ E++ + RI I H+L+I R D G YT V G +
Sbjct: 3078 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVST 3137
Query: 519 LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW 578
+ ++++ + K+E I + A+V N+ +D A W
Sbjct: 3138 AKLFVEGRDVRIRSI-KKEVQVIE-------KQRAVVEFEVNEDDVD----------AHW 3179
Query: 579 LK-GDEVFTTTEGRTR--IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
K G E+ + R + +E+R+ I ++ D G YT G + +S+ L
Sbjct: 3180 YKDGIEINFQVQERHKYVVERRI--HRMFISETRQSDAGEYTF----VAGRNRSSVTL-Y 3232
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNFEVFT 694
V+ P+PP+ ++ +P GKP ++ + + W K E
Sbjct: 3233 VNAPEPPQVLQ-----------ELQPVTVQSGKPARFCAVISGRPQPKISWYK--EEQLL 3279
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTT 754
T ++ + +G Y + + + + K +A TS L + V +V
Sbjct: 3280 STGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3339
Query: 755 LKWRPP 760
+ PP
Sbjct: 3340 MPVYPP 3345
Score = 117 bits (293), Expect = 6e-26
Identities = 130/526 (24%), Positives = 205/526 (38%), Gaps = 68/526 (12%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF--EVFTET 696
P PEA+ T D L W+PP +DGG + GY+VE +K G + W + N E ET
Sbjct: 17116 PVNPEAIDTTCNSVD---LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 17172
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLK 756
Y+ T + +G Y+ RV AVNA G S P+ +P + + EP LI++ +K
Sbjct: 17173 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIK 17231
Query: 757 WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR------ 810
R+ A +++ W + + + V P G+++ R
Sbjct: 17232 VGDTLRLSA------IIKGVPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHED 17283
Query: 811 --VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF---- 864
+ + + + T++ V + + PP R L + IRK L P
Sbjct: 17284 GGIYSLTVENPAGSKTVSVKVLVLDKPGPP-----RDLEVSEIRKDSCYLTWKEPLDDGG 17338
Query: 865 --------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI 916
+ + W+ A + + + R AA + G +
Sbjct: 17339 SVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPF---V 17395
Query: 917 ENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKT 976
E K + + GPP ++ +V T + W P DG S I GY V+ ++ T
Sbjct: 17396 ETPKPIKALD--PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT 17453
Query: 977 MEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
+W ++ + C V+ L G Y FRV ENI GL G+ T P
Sbjct: 17454 QDWIK-FKTVTNLECVVTGLQQGKTYRFRVKAENIVGL----GLPDTTI----------P 17498
Query: 1037 FEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
E +E + + LI+ +VV AG + +RG P P W + EI+ D +
Sbjct: 17499 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 17558
Query: 1096 I--TNYQGVLTLN--IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N+ VLT+ +RR D G Y N G L V
Sbjct: 17559 VETDNFSSVLTIKNCLRR----DTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 117 bits (293), Expect = 6e-26
Identities = 82/297 (27%), Positives = 135/297 (45%), Gaps = 18/297 (6%)
Query: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
+ +++ +G LR+ + G P P TW K D V I + +S + A R+
Sbjct: 27966 DGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGSTSLFVRDATRD 28024
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPV 670
G YT++ N G A I ++V D P +R T++ + L W+ P+ DG P+
Sbjct: 28025 HRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPI 28084
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
T Y++E+++ W + + + +Y + K+I G Y+ RV AVN GV +P +++ P
Sbjct: 28085 THYIIEKRETSRLAWALIEDKCEAQ-SYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDP 28142
Query: 731 F-------MPIAP-TSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+P AP EP ++T + TL W P G I Y++E + S
Sbjct: 28143 VVAQIQYTVPDAPGIPEP-----SNITGNSITLTWARPESDGGSEIQQYILERREKKSTR 28197
Query: 783 WVPA-NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
WV + P+ F V L G F V+ N AG + +++ + RE PP
Sbjct: 28198 WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 28254
Score = 117 bits (292), Expect = 8e-26
Identities = 112/425 (26%), Positives = 166/425 (39%), Gaps = 46/425 (10%)
Query: 729 KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
KP +P P ++VT TLKW PP G I Y++E + +WV
Sbjct: 20075 KPGIPTGPIK------FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC-A 20127
Query: 789 EPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPVTIREIAEPPKIRLP 843
V++ F V L G FRV N G +SEP P + + PP I
Sbjct: 20128 SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDV 20187
Query: 844 RH----LRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFV 899
RH L T +K G + K R ++W + ++ +R DF
Sbjct: 20188 RHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA------NKTPIRMRDF------ 20235
Query: 900 RQAARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
+ ++ EYE V N+ + + ++ PP V + + + W
Sbjct: 20236 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWT 20295
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
PK DG ++ GY V+K D + W N + TV+DL+ G +Y FR+ +N G
Sbjct: 20296 EPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAG 20355
Query: 1014 LSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC-AVR 1072
+P S T I K EY+ + P L + AG + LN ++
Sbjct: 20356 AISAPSESTETI-ICKD-------EYEAPTIVLDPTIKDGL---TIKAGDTIVLNAISIL 20404
Query: 1073 GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAE 1132
G P PK W K +IR IT+ L I+ + DAG YT A N G +
Sbjct: 20405 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 20464
Query: 1133 CKLEV 1137
K+ V
Sbjct: 20465 VKVTV 20469
Score = 115 bits (287), Expect = 3e-25
Identities = 132/509 (25%), Positives = 215/509 (42%), Gaps = 64/509 (12%)
Query: 159 DASGQSLESFKRTSEK---KSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIW 215
+ S + FKR +E+ ++ TA EL +K++ EE +K KD E+
Sbjct: 1992 EESEELRSKFKRRTEEGYYEAITAVELKS----RKKDESYEELLRKTKD--------ELL 2039
Query: 216 ELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLD--PAYQVDRGNK 273
K + E + +A + IT + K K+E+ S K + + V +G+
Sbjct: 2040 HWTKELTEEEKKALAEEGKIT-----IPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSD 2094
Query: 274 IKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVF----ENVGKKRILTINKCTLADDAAYEV 328
V + PD +W+KNG +I+ S + + +NV + L I T D A+ V
Sbjct: 2095 AHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE---LVIRDVTAEDSASIMV 2151
Query: 329 A---VKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAV---EVSEEGAQVMWMKDG 382
+ E + + LI E Q V ++ MA E SE +V W KDG
Sbjct: 2152 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2211
Query: 383 VELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI---TNGGQCEAELIVEEKQL 439
+E+ D +YR D K H L + D Y + + A+LIVE +
Sbjct: 2212 MEVHEGD----KYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVV 2267
Query: 440 EVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
E ++++ D+ V S +C VS E + GKWY N VE++ + + TI+ L + D
Sbjct: 2268 EFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKD 2327
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V ED+G+Y+FV DG + K+ K P I S + V G
Sbjct: 2328 VTKEDQGEYSFVIDGKKTTCKLKM-----------KPRPIAILQGLSDQK------VCEG 2370
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+ ++L+V ++ E W+K G EV + I+K+ +IE +ED G Y+
Sbjct: 2371 DIVQLEVKVSLESVE-GVWMKDGQEVQPSDRVHIVIDKQ--SHMLLIEDMTKEDAGNYSF 2427
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ + + VDV P + V +
Sbjct: 2428 TIPALGLSTSGRVSVYSVDVITPLKDVNV 2456
Score = 114 bits (286), Expect = 4e-25
Identities = 253/1142 (22%), Positives = 419/1142 (36%), Gaps = 150/1142 (13%)
Query: 46 TAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFS 105
T +EP F + PDSV V G + + G P K +KWFKG
Sbjct: 6829 TVQEPPS-FEQTPDSVEVLPGMSLTFTSVIRGTP-PFK--VKWFKGS---------RELV 6875
Query: 106 FKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSL 165
ES N + + EL + +V + G Y V SC ++ V+ P + L
Sbjct: 6876 PGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFV--KRL 6933
Query: 166 ESFKRTSEKKSDTAGELDFSGL-------LKKREVVEEEKKKKKKDDDDLGIPPEIWELL 218
F + E S E ++G +K ++ + ++ + I E+L
Sbjct: 6934 ADF--SVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEK----STILEIL 6987
Query: 219 KGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMV 278
+ S E A QY + + +A V V + F + L+ V G L
Sbjct: 6988 E----STIEDYA-QYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVI-GEPATLQC 7041
Query: 279 EISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY------EVAVK 331
++ P++ + W+K +++ + Y + L INK +D Y V
Sbjct: 7042 KVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAV 7101
Query: 332 DEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDS 390
+ ++ P L+D +G V ++ E QV W KDGV L + +
Sbjct: 7102 ASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDAN 7161
Query: 391 FKARYRFKKDGKRHILIFSDVVQEDR---GRYQVITNG----GQCEAELIVEEKQLEVLQ 443
+ + H + ++Q D+ G+Y + A+LI+ E ++
Sbjct: 7162 LQTSF-------VHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFF 7214
Query: 444 DIADLTVKAS--EQAVFKCEVSDE---KVTGKWYKNGVEVRPSKRITISHVGRFHKLVID 498
D+ ++V + E FKC V+ K+T W K+ E+RP ++ V L +
Sbjct: 7215 DLKPVSVDLALGESGTFKCHVTGTAPIKIT--WAKDNREIRPGGNYKMTLVENTATLTVL 7272
Query: 499 DVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA 558
V D G YT YA +++ K + + QEPP+ K E + +V
Sbjct: 7273 KVGKGDAGQYTC----YASNIAGK----DSCSAQLGVQEPPRFI-----KKLEPSRIVKQ 7319
Query: 559 GNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
R + I G P W K DE + R+ + + + ED G YT
Sbjct: 7320 DEFTRYECKIGGSPEIKVLWYK-DETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTC 7378
Query: 619 KVTNPVGEDVASIFLQVVD------VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTG 672
+ N G +S L+V + P P E ++ V + L PP + V+
Sbjct: 7379 EAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLE-CELQGTPPFH-----VSW 7432
Query: 673 YLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG--VSQPSMNTKP 730
Y +R+ + +++ K+ E F T+ + + E + A N +G S+ K
Sbjct: 7433 YKDKRELRSGKKY-KIMSENFL-TSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 7490
Query: 731 FMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP 790
+ +V TT++ P + G +V E W+ + +E
Sbjct: 7491 PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVR---ESDNIWI-SYSEN 7546
Query: 791 VERCGFTVKNLPTGARILFRVVGVNIAGRSEP-ATLA--QPVTIREIAEPPKIRLPRHLR 847
+ F+ + ++ N AG E ATL+ +P TI E E K+
Sbjct: 7547 IATLQFSRVEPANAGKYTCQI--KNDAGMQECFATLSVLEPATIVEKPESIKV------- 7597
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVR--QAARS 905
G+ L G P W K G L TS + S F+ V ++ A S
Sbjct: 7598 -----TTGDTCTLECTVAGTPELSTKWFKDGKEL-TSDNKYKISFFNKVSGLKIINVAPS 7651
Query: 906 DSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
DSG Y VQ KD+ T ++V ++ PP +++ TN L G+S +M
Sbjct: 7652 DSGVYSFEVQNPVGKDSCTASLQVSDRTVPP--SFTRKLKETNGL--------SGSSVVM 7701
Query: 966 GYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL-------SDSP 1018
V + ++ WF +E N I Y T+N C L SDS
Sbjct: 7702 ECKVYGSPPISVSWF--HEGNE---------ISSGRKYQTTLTDNTCALTVNMLEESDSG 7750
Query: 1019 GVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPK 1078
+ + + P +E P F+ V+ G + V+G P
Sbjct: 7751 DYTCIATNMAGSDECSAPLTVRE-----PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFS 7805
Query: 1079 VVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
V W K E+ + ++ V L + +G YTC NE G+A L ++
Sbjct: 7806 VSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Query: 1139 VP 1140
P
Sbjct: 7866 AP 7867
Score = 114 bits (286), Expect = 4e-25
Identities = 137/562 (24%), Positives = 213/562 (37%), Gaps = 62/562 (11%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE-DVASIFLQVVDV---PDP 641
T T+ R R+ + S+ A G VGE S+F + D P P
Sbjct: 24955 TLTDLRLRVTGLTEGHSYEFRVAAENAAG---------VGEPSEPSVFYRACDALYPPGP 25005
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYES 700
P ++T L W P+YDGG PV GY+VE K+ + W + +
Sbjct: 25006 PSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 25065
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTS-EP--------LHLIVEDVTDT 751
TK+ E Y R+ A+N+ GV +P+ T P +A EP L +V
Sbjct: 25066 TKLKENTEYNFRICAINSEGVGEPA--TLPGSVVAQERIEPPEIELDADLRKVVVLRASA 25123
Query: 752 T----TTLKWRPPNRIGAGGIDGYLVEYC-LEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+K RP + +G L + +E + + + V R NL
Sbjct: 25124 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 25183
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ VN+ P+ +TIRE+ K + I + N +V +
Sbjct: 25184 SGSKTAFVNVRVLDSPSAPVN-LTIREVK---KDSVTLSWEPPLIDGGAKITNYIVEKRE 25239
Query: 867 KPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
R T R+ F V S EY + + E T
Sbjct: 25240 TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA-----SNEYGIGLPAET-----TEP 25289
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++V E PP V + +V A ++W+ P+ DG S+I GY V+ K + +W + +
Sbjct: 25290 VKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKW-STCTQV 25348
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP-FEYKEHDFR 1045
+ T+S L G EY FRV N G SD + ++ I KP E H F
Sbjct: 25349 KTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG---VPVIARDIEIKPSVELPFHTFN 25405
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
V A ++ +G P+ V W K+ ++E + +++ + V +L
Sbjct: 25406 -------------VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 25452
Query: 1106 NIRRPSPFDAGTYTCRAVNELG 1127
+I+ S D GTY N G
Sbjct: 25453 SIKEASKEDVGTYELCVSNSAG 25474
Score = 111 bits (277), Expect = 4e-24
Identities = 74/266 (27%), Positives = 120/266 (45%), Gaps = 9/266 (3%)
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFE 305
K ++K A KK V VE++ P++ ++W KNG ++ + KY
Sbjct: 2697 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2756
Query: 306 NVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEM 365
G L I C + D++ Y + L V+ V I+ +D V
Sbjct: 2757 VKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVET--VKIIKKPKDVTALENATVAF 2814
Query: 366 AVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNG 425
V VS + V W VE+ D ++R + K H L+ ++ D G Y +
Sbjct: 2815 EVSVSHDTVPVKWFHKSVEIKPSD----KHRLVSERKVHKLMLQNISPSDAGEYTAVVGQ 2870
Query: 426 GQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRIT 485
+C+A+L VE L + + + ++ V ++ A F+CEVS V W KNGVE+ S++
Sbjct: 2871 LECKAKLFVET--LHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFK 2928
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFV 511
I G+ H+L+I + ED +YTFV
Sbjct: 2929 IVVQGKLHQLIIMNTSTEDSAEYTFV 2954
Score = 110 bits (274), Expect = 1e-23
Identities = 200/936 (21%), Positives = 339/936 (36%), Gaps = 122/936 (13%)
Query: 250 VEVKKSAAFTKKL-DPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVG 308
+ +K F KKL D + V + +++ +E ++P +++ WFK+ EI S ++ +
Sbjct: 7486 IALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEP-ISVVWFKDKGEIVRESDNIWISYS 7544
Query: 309 KK-RILTINKCTLADDAAYEVAVKDE----KCFTELFVKEPPVLIVTPLEDQQVFVGDRV 363
+ L ++ A+ Y +K++ +CF L V EP ++ P E +V GD
Sbjct: 7545 ENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKP-ESIKVTTGDTC 7603
Query: 364 EMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY--- 419
+ V+ W KDG ELT ++ +K + K G + I +V D G Y
Sbjct: 7604 TLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKII----NVAPSDSGVYSFE 7659
Query: 420 -QVITNGGQCEAELIVEEKQL--EVLQDIADLTVKASEQAVFKCEV-SDEKVTGKWYKNG 475
Q C A L V ++ + + + + + V +C+V ++ W+ G
Sbjct: 7660 VQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEG 7719
Query: 476 VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALS--LSAKLNFLEIKVEYV 533
E+ ++ + L ++ + D GDYT + A S SA L E +V
Sbjct: 7720 NEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE-PPSFV 7778
Query: 534 PKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR 593
K +P + V+ G + + G PP +W KG + R
Sbjct: 7779 QKPDP---------------MDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGD-RCN 7822
Query: 594 IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGED 653
+ + + G YT V+N G+ + L + P + V+ + D
Sbjct: 7823 VSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYI---KAPAKFVKRLN---D 7876
Query: 654 WAILVWEPPMYDG---GKPVTGYLVERKKKG-----SQRWMKLNFEVFTETTYESTKMIE 705
++I +P + +G G P V KK G SQR E S+ + +
Sbjct: 7877 YSIEKGKPLILEGTFTGTPPIS--VTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVED 7934
Query: 706 GILYEMRVFAVNAIGVSQPSMNTKPFMP--IAPTSEPLHLIVEDVTDTTTTLKWRPPNRI 763
Y + NA G S P EP+ + V D L P
Sbjct: 7935 AGQYNC--YIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTP---- 7988
Query: 764 GAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG----R 819
E W +T+ + + A ++F V +N +G +
Sbjct: 7989 --------------EIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICK 8034
Query: 820 SEPA----TLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ----GKPRPQ 871
+E + + + +T++E PP RQ +R V E + L V F G
Sbjct: 8035 AENSVGEVSASTFLTVQEQKLPPSFS-----RQ--LRDVQETVGLPVVFDCAISGSEPIS 8087
Query: 872 VVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
V W K G PL D+ V D + + RS +G+Y + +++ R+ +
Sbjct: 8088 VSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILT 8147
Query: 931 EKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEI-MGYFVQKADKKTMEWFNVYER 985
E PP + V V G +A E G I + + + ++ + +
Sbjct: 8148 EGKNPPFFDIRLAPVDAVVGESADFECHVT---GTQPIKVSWAKDSREIRSGGKYQISYL 8204
Query: 986 NRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFR 1045
TV + G+ + Y N G R++ T + E E
Sbjct: 8205 ENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEE--- 8261
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
G S L V G V W KN +EI+ IT L L
Sbjct: 8262 --------------TEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL 8307
Query: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+R+ DAG YTC+ N+ G AL + ++ P+
Sbjct: 8308 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPK 8343
Score = 108 bits (271), Expect = 2e-23
Identities = 107/416 (25%), Positives = 166/416 (39%), Gaps = 37/416 (8%)
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
+P S L +D+ + + WRPP G I GY++E W ++ V
Sbjct: 30227 SPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGT 30285
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK--IRLPRHLRQT--- 849
VK L FRV N G S+P +PVT + PP+ P L T
Sbjct: 30286 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSS 30345
Query: 850 ----YIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDF-DTVFFVRQA 902
+ R + + V + + K W + T+ ++ T D + R
Sbjct: 30346 VSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRII 30405
Query: 903 ARSDSGEYELSVQIENM--KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDG 960
A++D G E S E + KD +K P + + + + ++W+ P+ DG
Sbjct: 30406 AQNDVGLSETSPASEPVVCKDP-------FDKPSQPGELEILSISKDSVTLQWEKPECDG 30458
Query: 961 NSEIMGYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
EI+GY+V+ W ER + T+ L+ EY FRV+ EN GLS
Sbjct: 30459 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP-- 30516
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKV 1079
+ TA +KT +T AP + D G +A L+C + G P P +
Sbjct: 30517 --RRTAMSIKTKLTSGE----------APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 30564
Query: 1080 VWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
W + E+ + K+ +++ TL + D G YTC A NE+GE KL
Sbjct: 30565 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 30620
Score = 108 bits (270), Expect = 3e-23
Identities = 208/938 (22%), Positives = 345/938 (36%), Gaps = 133/938 (14%)
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFEN 306
A + VK+ A F +KL+P+ + +G+ +L +++ P + + WF N +EIK SSK+
Sbjct: 4291 ANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSF 4350
Query: 307 VGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKEPPVLI--VTPLEDQQVFVG 360
V +L + + D Y ++E C + + VKE P P+E + +
Sbjct: 4351 VESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEY-- 4408
Query: 361 DRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ 420
D + +A ++ W KD L +K F +D + I V D G YQ
Sbjct: 4409 DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKT---FIQDHLVSLQILK-FVAADAGEYQ 4464
Query: 421 V-ITN---GGQCEAELIVEE-----KQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKW 471
+TN C A + + E K++E + T A+ QA K + +T W
Sbjct: 4465 CRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGT--AAFQATLKGSL---PITVTW 4519
Query: 472 YKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVE 531
K+ E+ I ++ L + + + +G Y A + L +K
Sbjct: 4520 LKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDA-GIQRCSALLSVK-- 4576
Query: 532 YVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEG 590
EP I + +I V G+ L V +G A W K G E+ T
Sbjct: 4577 -----EPATITEEAV------SIDVTQGDPATLQVKFSGTKEITAKWFKDGQEL--TLGS 4623
Query: 591 RTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE-AVRITS 649
+ +I S I S +++D G YT +V N VG + V+D+ PP ++
Sbjct: 4624 KYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKK 4683
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI-L 708
+ + + G P++ + ++ S K F T + +EG
Sbjct: 4684 MDSIKGSFIDLECIVAGSHPISIQWFKDDQEISAS-EKYKFSFHDNTAFLEISQLEGTDS 4742
Query: 709 YEMRVFAVNAIGVSQPS----MNTKPFMPIAPTSEPLH----LIVEDVTDTTT--TLKWR 758
A N G +Q S + P+ P S+ ++ + ++ + T T+KW
Sbjct: 4743 GTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWF 4802
Query: 759 PPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG 818
N+ G W + +E F K +G I + ++
Sbjct: 4803 KDNKELHSG----------AARSVWKDDTSTSLEL--FAAKATDSGTYIC--QLSNDVGT 4848
Query: 819 RSEPATLAQPVTIREIAEPPK-IRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKG 877
+ ATL + EPP+ I+ P + + G+ G P+ +V W
Sbjct: 4849 ATSKATLF-------VKEPPQFIKKP---SPVLVLRNGQSTTFECQITGTPKIRVSWYLD 4898
Query: 878 GAPLDTSRVH-VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE----- 931
G + + H + D F + A +SG Y + + + +I ++V E
Sbjct: 4899 GNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFI 4958
Query: 932 KAGPPINV-------MVKEVWGTNAL-VEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
+ P+ V + EV GT V W N EI ++ KK V
Sbjct: 4959 RELKPVEVVKYSDVELECEVTGTPPFEVTWL----KNNREI------RSSKKYTLTDRVS 5008
Query: 984 ERNRH-TSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
N H T C SD EY C +S+ G + R+
Sbjct: 5009 VFNLHITKCDPSDT---GEYQ--------CIVSNEGGSCSCSTRVA-------------- 5043
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
+ P F+ + + V SA V G P + W+K+ + ED I+ V
Sbjct: 5044 -LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSV 5102
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
TL IR +G YTC+A NE G L V+ P
Sbjct: 5103 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEP 5140
Score = 107 bits (266), Expect = 8e-23
Identities = 121/519 (23%), Positives = 189/519 (36%), Gaps = 75/519 (14%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF-EVFTETT 697
P PP ++ L W P YDGG P+ GYLVE K+ S W++ N + +T
Sbjct: 19589 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 19648
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT----- 752
+E T ++E Y+ RV+AVN IG S PS P P + D+ T
Sbjct: 19649 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 19708
Query: 753 ------TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RPP +I W N +R G +K+
Sbjct: 19709 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKSTDFDTF 19750
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ V AG+ TL +E K+ + G +N+ V
Sbjct: 19751 LRCENVNKYDAGKYI-LTLENSCGKKEYTIVVKV----------LDTPGPPVNVTVKEIS 19799
Query: 867 KPRPQVVWTK----GGAPLDTSRVHVRTSDFDTVFFV---------RQAARSDSGEYELS 913
K V W GG+P+ V R ++ + V R A + Y
Sbjct: 19800 KDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFR 19859
Query: 914 VQIEN---MKDTATIR--IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V EN + D R ++ + GP +++ V+ V ++ + W+ P DG S I+GY
Sbjct: 19860 VFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYV 19919
Query: 969 VQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
V ++ +W V ++ + DL G EY FRV EN + G +
Sbjct: 19920 VDFLTEEN-KWQRVM-KSLSLQYSAKDLTEGKEYTFRVSAEN----ENGEGTPSEITVVA 19973
Query: 1029 KTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI 1088
+ + + K P + + + L ++G P P V W K + +
Sbjct: 19974 RDDVVAPDLDLKG----------LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPL 20023
Query: 1089 REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
D + + + TL + DAG YT N G
Sbjct: 20024 ATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 20062
Score = 107 bits (266), Expect = 8e-23
Identities = 108/487 (22%), Positives = 190/487 (39%), Gaps = 42/487 (8%)
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTET-TYESTKMIEGILYEMRVFAVNAIGVSQPS 725
GKP+ + R + M+ N E+ E T + + + A N+ G ++
Sbjct: 26502 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 26561
Query: 726 MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVP 785
+N P + P+ ++ D+T+ + TLKW PP G + Y++ + W
Sbjct: 26562 INIVVLDRPGPPTGPV--VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 26619
Query: 786 ANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRL 842
+ V R V L TG FR+ N G S+ A VT++ PP
Sbjct: 26620 VSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSAC-VTVKLPYTTPGPPSTPW 26677
Query: 843 PRHLRQTYI-----RKVGEQLNLVVPF--QGKPRPQVVWTKGGA-PLDTSRVHVRTSDFD 894
++ + I V + VV + + K R ++W K + T+ V T
Sbjct: 26678 VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAG 26737
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
++ R A + +G + S E + ++ PP NV + ++ + + WQ
Sbjct: 26738 LIYEFRVYAENAAGVGKPSHPSEP--------VLAIDACEPPRNVRITDISKNSVSLSWQ 26789
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I GY V++ D W N T +S L ++Y FRV+ N G
Sbjct: 26790 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 26849
Query: 1014 LSDSPGVSKNTARILKT---GITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
+P + + + P EY E K+ AG S L
Sbjct: 26850 SISNPSEVVGPITCIDSYGGPVIDLPLEYTE-----VVKYR---------AGTSVKLRAG 26895
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
+ G P P + W K+ E++ + + N + ++ I+ ++G Y + N +G A
Sbjct: 26896 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 26955
Query: 1131 AECKLEV 1137
A ++++
Sbjct: 26956 ATIRVQI 26962
Score = 106 bits (265), Expect = 1e-22
Identities = 114/409 (27%), Positives = 180/409 (44%), Gaps = 52/409 (12%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
EIS+ D+ +W G+ ++PS + G KR LT++K L D A EV + T
Sbjct: 11419 EISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKL--DQAGEVLYQALNAITT 11476
Query: 339 --LFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-VSEEGAQVMWMKDGVELTREDSFKARY 395
L VKE + PL+D V V +R + E V A V+W K + D F
Sbjct: 11477 AILTVKEIELDFAVPLKD--VTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFD--- 11531
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQ 455
DGK+HIL+ +D +D G Y G + A L V +L+ + + D TVK E
Sbjct: 11532 -IIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGET 11590
Query: 456 AVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
A F CE+S EK+ W+KN ++ S+ + IS G+ HKL + +V +D
Sbjct: 11591 ATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQ--IKAQVK 11648
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
LS +A+L LE P + KT+ V +++ L ++ + P
Sbjct: 11649 ELSSTAQLKVLE---------ADPYFTVKLHDKTA------VEKDEITLKCEVSKDVP-- 11691
Query: 576 ATWLK-GDEVFTT------TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 628
W K G+E+ + +G RI K I+ A +D+G Y +
Sbjct: 11692 VKWFKDGEEIVPSPKYSIKADGLRRILK--------IKKADLKDKGEYVCDCGTDKTKAN 11743
Query: 629 ASIFLQVVDVPDPPEAVRITSVGE--DWAILVWEPPMYD----GGKPVT 671
++ +++ V P V + VGE + I + EP ++ G+P+T
Sbjct: 11744 VTVEARLIKVEKPLYGVEV-FVGETAHFEIELSEPDVHGQWKLKGQPLT 11791
Score = 103 bits (256), Expect = 1e-21
Identities = 109/405 (26%), Positives = 177/405 (43%), Gaps = 35/405 (8%)
Query: 249 KVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVG 308
KV+V + AA ++ G K + + IS ++W ++ + ++ KY G
Sbjct: 12544 KVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADG 12603
Query: 309 KKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE 368
KKR+L + TL D Y V V + L V E + IV PL+D +V V E
Sbjct: 12604 KKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCE 12662
Query: 369 VSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV-ITN--- 424
V+ EGA+ W ++ E DS ++Y + + L D +D+ Y V +TN
Sbjct: 12663 VNTEGAKAKWFRN--EEAIFDS--SKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 12718
Query: 425 -GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKR 483
+ A LIVEE+ L +++ + D+ + F C+V+ VT KW KNG EV R
Sbjct: 12719 ENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNR 12778
Query: 484 ITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHL 543
++ H L I D DEG+Y V G S+ A+L +E E+V HL
Sbjct: 12779 VSYRVDKYKHMLTIKDCGFPDEGEY-IVTAGQDKSV-AELLIIEAPTEFVE-------HL 12829
Query: 544 DCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT-RIEKRVDCSS 602
+ T + V ++ E V + G E+ EG+ + EK
Sbjct: 12830 EDQTVTEFDDAV--------FSCQLSREKANVKWYRNGREI---KEGKKYKFEKDGSIHR 12878
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQ--VVDVPDPPEAV 645
+I+ + +DE Y V + + A +F++ V++ PP+ +
Sbjct: 12879 LIIKDCRLDDECEYACGVED--RKSRARLFVEEIPVEIIRPPQDI 12921
Score = 102 bits (254), Expect = 2e-21
Identities = 114/516 (22%), Positives = 191/516 (37%), Gaps = 76/516 (14%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP +RI + L W P+YDGG VTGY+VE ++ + W ++ +
Sbjct: 27164 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223
Query: 696 TT-YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMP-------------------IA 735
TT Y + + G+ Y RV AVN G +P +P IA
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIA 27283
Query: 736 PTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERC 794
E + +++ T+ WR + G Y +E S +P T +
Sbjct: 27284 KAGEDVQVLIPFKGRPPPTVTWRKDEK-NLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 27342
Query: 795 GFTVKN---LPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
T++N P + + +V+ A + T+ + +PP I + I
Sbjct: 27343 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
K + + W+ ++ + T FF R A ++ G E
Sbjct: 27403 EK-------------RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 27449
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
E +K E P ++ +K+ T+ ++ W P DG S I Y V++
Sbjct: 27450 PCETTEPVK--------AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 27501
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
K W + ++ VS L + FRV+ +N GLSD
Sbjct: 27502 KGKGEQTWSHA-GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------- 27546
Query: 1032 ITFKPFEYKEHDFRMAPKFLTPLIDR--------VVVAGYSAALNCAVRGHPKPKVVWMK 1083
+T P KE +TP +D V G++ L +G PKP + W+K
Sbjct: 27547 VTIGPITVKE-------LIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLK 27599
Query: 1084 NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1119
+ + ++E + + +TL+I+ G YT
Sbjct: 27600 DGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 27635
Score = 99.8 bits (247), Expect = 1e-20
Identities = 71/264 (26%), Positives = 127/264 (48%), Gaps = 11/264 (4%)
Query: 268 VDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K L ++S PD+T +KW+ N ++IKP + G K+ L IN+ +D+ Y
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2515
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMW-MKDGVEL 385
++ V + L V++ + I+ L D V VE+S G V+W KD
Sbjct: 2516 KLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKD---- 2569
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+E ++Y+ + GK + L +++++D G+Y +L V + + +
Sbjct: 2570 -KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPL 2626
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
D TV S++AVF+CEV++ G+W ++G + + I G +L+I + +D
Sbjct: 2627 TDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDI 2686
Query: 506 GDYTFVPDGYALSLSAKLNFLEIK 529
G+YT+ S K+ ++IK
Sbjct: 2687 GEYTYKVATSKTSAKLKVEAVKIK 2710
Score = 99.0 bits (245), Expect = 2e-20
Identities = 109/513 (21%), Positives = 188/513 (36%), Gaps = 49/513 (9%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV-FTETT 697
P PP ++ + L W P+YDGG + GY+VE+ W +T
Sbjct: 22838 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 22897
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP---LHLIVEDVTDTTT- 753
E K++E Y R+ A+N GV + + P + P L L + + +
Sbjct: 22898 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 22957
Query: 754 -------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RP + G +DG + + + + + V +G
Sbjct: 22958 GSLRLFVPIKGRPTPEVKWGKVDGEIRDAAI------IDVTSSFTSLVLDNVNRYDSGKY 23011
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF-Q 865
L + T + VT+R + P P +L+ T I K + P
Sbjct: 23012 TLTL--------ENSSGTKSAFVTVRVLDTPSP---PVNLKVTEITKDSVSITWEPPLLD 23060
Query: 866 GKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE---NMKDT 922
G + + + S V T+ + + Q S + ++ + E +
Sbjct: 23061 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 23120
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I+V E PP + V +V + + W P+ DG S+I+ Y V+ K + +W
Sbjct: 23121 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 23180
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
R + +++L G EY FRV N G SD R L I K
Sbjct: 23181 -ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP--------RSLAVPIVAK------- 23224
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P V G + + G PKP + W K+ + +++ + +T+ +
Sbjct: 23225 DLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDL 23284
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
TL+I+ D G Y N +G+ A ++
Sbjct: 23285 TTLSIKETHKDDGGQYGITVANVVGQKTASIEI 23317
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/541 (23%), Positives = 199/541 (36%), Gaps = 74/541 (13%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP + + L W+PP DGG P+ GY+VE +++G+ W ++N TT
Sbjct: 15705 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 15764
Query: 699 EST--KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT--- 753
E + E Y RV AVN G S+PS T EP I D
Sbjct: 15765 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 15824
Query: 754 --------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGA 805
+K RP + + DG + +G + +P + + +V +P
Sbjct: 15825 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 15882
Query: 806 RILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-- 863
R + ++ T V + ++ PPK L+ + I + +L+ +P
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 15937
Query: 864 ----------FQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + WTK ++ V + +F R A + G +
Sbjct: 15938 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG---IG 15994
Query: 914 VQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--- 970
+E ++ T T R + PPI + + + + W+ PK+DG S + Y V+
Sbjct: 15995 PPVETIQRT-TARDPIYPP-DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 16052
Query: 971 --KADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
K W +R+ TV DL+ G EY FRV N G+S
Sbjct: 16053 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVS------------ 16100
Query: 1028 LKTGITFKPFEYKEHDFRMAPKFLTPLID----RVVVAGYSAALNCAVRGHPKPKVVWMK 1083
K T P + + D + P ID V G + + ++G P P + W K
Sbjct: 16101 -KPSATVGPCDCQRPD-------MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 16152
Query: 1084 -------NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
NK + D TL I + D G YT AVN LG A E +L
Sbjct: 16153 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 16212
Query: 1137 V 1137
V
Sbjct: 16213 V 16213
Score = 97.4 bits (241), Expect = 7e-20
Identities = 101/436 (23%), Positives = 166/436 (38%), Gaps = 41/436 (9%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N+ G + ++N P + P+ + ++VT + TL W PP G I+ Y+VE
Sbjct: 22224 NSAGEAIETLNVIVLDKPGPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKR 22281
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS-----EPATLAQPVTI 831
+ W + V R L TG FR+ N G+S EP P +
Sbjct: 22282 DTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 22340
Query: 832 REIAEPPKIRLPRH--LRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVH 887
P + L + + + + + V+ + + K R ++W K ++
Sbjct: 22341 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVK------LNKTP 22394
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENM----KDTATIRIRVV-EKAGPPINVMVK 942
+ + F T + EYE V EN+ K + V + PP
Sbjct: 22395 IPQTKFKTT------GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAI 22448
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR-HTSCTVSDLIVGNE 1001
V + ++W+ P DG S+I GY V+K + W N T V+ L+ +
Sbjct: 22449 IVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHR 22508
Query: 1002 YYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVA 1061
Y FRV N G+ P S TG E M PK+ + VV A
Sbjct: 22509 YEFRVIARNAAGVFSEPSES--------TGAITARDEVDPPRISMDPKYKDTI---VVHA 22557
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
G S ++ + G P P + W+K E+ + I + +L+++ D+G Y +
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 22617
Query: 1122 AVNELGEALAECKLEV 1137
A N GE ++V
Sbjct: 22618 AKNVAGERSVTVNVKV 22633
Score = 95.5 bits (236), Expect = 3e-19
Identities = 116/453 (25%), Positives = 166/453 (36%), Gaps = 51/453 (11%)
Query: 694 TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT 753
T + + T +G Y + V N +G S+ P P+ +DV+ +
Sbjct: 23285 TTLSIKETHKDDGGQYGITV--ANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESI 23340
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813
TL W PP G I Y+V+ + W + V R V L TG FR+
Sbjct: 23341 TLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFA 23399
Query: 814 VNIAGRS---EPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLN------LVVPF 864
N G+S E + +E P + + + + E +N +
Sbjct: 23400 ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 23459
Query: 865 QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM---- 919
+ K R ++WTK ++ + +H DT F +A + G EYE V EN+
Sbjct: 23460 ERKERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVG 23506
Query: 920 ----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ + G P +MVK ++W P DG S I GY V+K D
Sbjct: 23507 KASKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLP 23563
Query: 976 TMEWFNVYERNR-HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF 1034
W N T TVS L Y FRV +N G P S TG
Sbjct: 23564 DGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDS--------TGPIT 23615
Query: 1035 KPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF 1094
E + M PKF + VV AG + L V G P P + W++ EI E +
Sbjct: 23616 AKDEVELPRISMDPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARC 23672
Query: 1095 LITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
I N L ++ D G Y RA N G
Sbjct: 23673 EIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 23705
Score = 94.4 bits (233), Expect = 6e-19
Identities = 72/213 (33%), Positives = 98/213 (46%), Gaps = 16/213 (7%)
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHT 989
EK G P + V + +V W+ P DG ++I Y+++K +KK +W +V E R T
Sbjct: 30823 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 30882
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK 1049
+V +LI G EY FRV EN+ G S+ +S +P K AP
Sbjct: 30883 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-------------EPITPKSDVPIQAPH 30929
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP-KFLITNYQ-GVLTLNI 1107
F L + V +A L C V GHPKP V W + EI D K+ I ++ G L I
Sbjct: 30930 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 30989
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
+ DA Y RA N+ G LEV VP
Sbjct: 30990 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 31022
Score = 94.0 bits (232), Expect = 7e-19
Identities = 181/889 (20%), Positives = 325/889 (36%), Gaps = 110/889 (12%)
Query: 285 LTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY-----EVAVKDEKCFTEL 339
+++ WF +I +KY L +N +D Y VA DE C L
Sbjct: 5829 ISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDE-CRAVL 5887
Query: 340 FVKEPPVLIVTPLEDQQVFVGDRVEMAVEV-SEEGAQVMWMKDGVELTREDSFKARYRFK 398
V+EPP + P E +V G V + +V W + EL + D +
Sbjct: 5888 TVQEPPSFVKEP-EPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYF--- 5943
Query: 399 KDGKRHILIFS-DVVQEDRGRYQVITNGGQ--CEAELIVEEKQLEVLQDIADLTVKASEQ 455
+D + +F+ D+ Q V N GQ C L V+E L+ ++D +V+ +
Sbjct: 5944 EDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAA-FLKRLSDHSVEPGKS 6002
Query: 456 AVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDG 514
+ + + ++ W K+G + S++ I + L I + D G Y+ +
Sbjct: 6003 IILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIEN 6062
Query: 515 YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPP 574
A ++ V EPP T + G+ + L + G P
Sbjct: 6063 EAGR--------DVCGALVSTLEPPYF------VTELEPLEAAVGDSVSLQCQVAGTPEI 6108
Query: 575 VATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
+W KGD ++ T E RT V ++ V D G YT K N +G +
Sbjct: 6109 TVSWYKGDTKLRPTPEYRTYFTNNV--ATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 6166
Query: 634 QVVDVPDPPEAVR-ITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV 692
++ + PP R + + + + V +G P+ V + G N +
Sbjct: 6167 RIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQ---VCWYRDGVLLRDDENLQT 6223
Query: 693 FTETTYESTKMIEGILYEMRVF---AVNAIGVSQPSMNT-------KPFMPIAPTSEPLH 742
+ K+++ L + A N +G + S PF I P S +
Sbjct: 6224 SFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVS--ID 6281
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLP 802
+I + D + P RI W N E +T+ +
Sbjct: 6282 VIAGESADFECHVTGAQPMRI------------------TWSKDNKEIRPGGNYTITCVG 6323
Query: 803 TGARILFRVVGVNIAGR---SEPATLAQPVTIREIA--EPPKIRLPRHLRQTYIRKVGEQ 857
+ VG +G+ + + + +++ EPPK + L + + K GE
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKF--VKKLEASKVAKQGES 6381
Query: 858 LNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQI 916
+ L G P +V W + + L S + ++ + + + +A+ DSG+Y +
Sbjct: 6382 IQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDY--ICEA 6439
Query: 917 ENMKDTATIRIRVVEKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEIMGYFVQ-K 971
N A+ + KA PP+ V + G++ +++ + G +V+ +
Sbjct: 6440 HNGVGDASCSTALTVKA-PPVFTQKPSPVGALKGSDVILQCEI---SGTPPFEVVWVKDR 6495
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
+ + F + ++ TS + +L + + N G SD+ S
Sbjct: 6496 KQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVG-SDTCSCSVK-------- 6546
Query: 1032 ITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKME-IRE 1090
F+ P+F+ L D + G + L V G VVW+K++ E IRE
Sbjct: 6547 ------------FKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRE 6594
Query: 1091 DPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
I+ + TL + P ++G Y C+ N+ G + EC + V
Sbjct: 6595 SENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAG--MRECSAVLTV 6641
Score = 94.0 bits (232), Expect = 7e-19
Identities = 95/391 (24%), Positives = 171/391 (43%), Gaps = 37/391 (9%)
Query: 240 GMLKRLKKAKVEVKK-SAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQ-EIK 297
G ++ AK+ V++ F K L+ V +G + L E++ + + W K+G+ ++
Sbjct: 11195 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVE 11253
Query: 298 PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFT-ELFVKEPPVL---IVTPLE 353
+ V +G R LTIN D Y V V++ VK V+ +V P+
Sbjct: 11254 KPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIR 11313
Query: 354 DQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQ 413
DQ V A +++++ + W K E+ E + K +DG L + +
Sbjct: 11314 DQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTE--ILRDGNHLYLKIKNAMP 11371
Query: 414 EDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYK 473
ED Y V G + A+L + E+++E+L+ I D+T+ E A F E+S+ + G+W
Sbjct: 11372 EDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKL 11431
Query: 474 NGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEY- 532
G +RPS I G L + V+ + G+ + +A L EI++++
Sbjct: 11432 KGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLY--QALNAITTAILTVKEIELDFA 11489
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
VP ++ + V + R + +T E + W KG ++ +++
Sbjct: 11490 VPLKD----------------VTVPERRQARFECVLTREANVI--WSKGPDIIKSSDKFD 11531
Query: 593 RI---EKRVDCSSFVIESAQREDEGRYTIKV 620
I +K + VI +Q +DEG YT +V
Sbjct: 11532 IIADGKKHI----LVINDSQFDDEGVYTAEV 11558
Score = 93.6 bits (231), Expect = 1e-18
Identities = 141/629 (22%), Positives = 246/629 (39%), Gaps = 109/629 (17%)
Query: 53 VFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNS 112
VF +KP V G D ++ +++G + + W K + SK +F H
Sbjct: 6459 VFTQKPSPVGALKGSDVILQCEISGTPPFE---VVWVKDRKQVRNSK---KFKITSKH-- 6510
Query: 113 ASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTS 172
+ LHI + D G Y + + D+C ++ + P R
Sbjct: 6511 ----FDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEP------------PRFV 6554
Query: 173 EKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPP--EIWELLKGA--KKSEYEK 228
+K SDT+ + ++ R +VE G P +W +G ++SE +
Sbjct: 6555 KKLSDTSTLI--GDAVELRAIVE-------------GFQPISVVWLKDRGEVIRESENTR 6599
Query: 229 IAF-------QYGITDLRGMLKRLKKAKVE--VKKSAAFTKKLDPAYQVDR--------G 271
I+F Q G + K + + K + +++ +A L+PA +++ G
Sbjct: 6600 ISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTG 6659
Query: 272 NKIKL-MVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV 330
N L V P+L+ KWFK+G+E+ SK+ + K L I ++D Y V
Sbjct: 6660 NPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEV 6719
Query: 331 KD----EKCFTELFVKE--PPVLIVTPLEDQQVFVGDRVEMAVEVSEEG-AQVMWMKDGV 383
K+ C + V + P + L+D +G V + VS V W +DG
Sbjct: 6720 KNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGN 6779
Query: 384 ELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV----ITNGGQCEAELIVEE--- 436
E+ ++ + L S + D G Y + +C A L V+E
Sbjct: 6780 EIVSGPKCQSSF----SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPS 6835
Query: 437 -----KQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGR 491
+EVL ++ LT + + +V KW+K E+ P + IS
Sbjct: 6836 FEQTPDSVEVLPGMS-LTFTSVIRGTPPFKV-------KWFKGSRELVPGESCNISLEDF 6887
Query: 492 FHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLN-FLEIKVEYVPKQEPPKIHLDCSGKTS 550
+L + +V+P + GDY+ + A S S + F++ +V K D S +T
Sbjct: 6888 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFV------KRLADFSVET- 6940
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
G+ + L+ + TG PP +W+K DE + R I + I +
Sbjct: 6941 --------GSPIVLEATYTGTPPISVSWIK-DEYLISQSERCSITMTEKSTILEILESTI 6991
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVP 639
ED +Y+ + N G+D+ + V++ P
Sbjct: 6992 EDYAQYSCLIENEAGQDICEALVSVLEPP 7020
Score = 92.8 bits (229), Expect = 2e-18
Identities = 113/454 (24%), Positives = 174/454 (38%), Gaps = 76/454 (16%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
NA G S+ K P + L V VT TL W P G I Y+VE
Sbjct: 29124 NASGTKAVSVMVKVLDSPGPCGK---LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERR 29180
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE--- 833
WV E + V L +FRV VN G P ++P+ R
Sbjct: 29181 ETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFT 29238
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVR 889
I PP I +VG GK + WTK GG + V R
Sbjct: 29239 IPSPPGIP----------EEVGT---------GKEHIIIQWTKPESDGGNEISNYLVDKR 29279
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE------------------ 931
++ + R D Y+ +++ ++ + + RV
Sbjct: 29280 EKK--SLRWTR--VNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISC 29335
Query: 932 -----KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
GPP V + + + W P DG ++I+GY ++ +K T +W+ V+
Sbjct: 29336 REPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNA 29395
Query: 987 --RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKE-HD 1043
R+T TV DL +G +Y FRV N+ G+S+ S++ A I +P E E D
Sbjct: 29396 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSE---YSESIAEI-------EPVERIEIPD 29445
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+A + R AG S L +V G P P + W K +++ + +I +
Sbjct: 29446 LELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITWSKQGIDLAS--RAIIDTTESYS 29500
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L + + + +DAG YT A N+ G+ A ++V
Sbjct: 29501 LLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 29534
Score = 91.7 bits (226), Expect = 4e-18
Identities = 62/245 (25%), Positives = 116/245 (47%), Gaps = 7/245 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G+ ++L V++S + W K+GQE++PS + + +L I T D Y
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2425
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVEL 385
+ T V V ++TPL+D V G + + +VS + V W + ++
Sbjct: 2426 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2485
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+D +A + G + L+ + D G Y++I + L VE+ +++++ +
Sbjct: 2486 KPDDRVQAIVK----GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEK--IKIIRGL 2539
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
DLT ++ VF+ E+S + W E++PS + I G+ +KL + ++ +DE
Sbjct: 2540 RDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDE 2599
Query: 506 GDYTF 510
G YTF
Sbjct: 2600 GKYTF 2604
Score = 91.3 bits (225), Expect = 5e-18
Identities = 106/430 (24%), Positives = 163/430 (37%), Gaps = 59/430 (13%)
Query: 734 IAPTSEPLHLI-VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
+ P S+P I +++ + L W P G G I Y +E W + V
Sbjct: 27654 LGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VA 27712
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
R F V NL A FRV N G ++QP+ I + R+P + I
Sbjct: 27713 RTTFKVPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPGPPGKPVIY 27766
Query: 853 KV---GEQLNLVVPF------------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
V G L P + K R ++W K ++TS + R
Sbjct: 27767 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK----VNTSPISGRE------- 27815
Query: 898 FVRQAARSDSGEYELSVQIENMKDTA--------TIRIRVVEKAGPPINVMVKEVWGTNA 949
R + +Y+ V EN + T+ + V+ G P + +V
Sbjct: 27816 -YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETI 27871
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYT 1008
++W P DG S+I+GY ++K W + TV+ L G+ Y FR+
Sbjct: 27872 TLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 27930
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALN 1068
N G P S +GI E P++ LI + +G S +
Sbjct: 27931 RNAVGTISPPSQS--------SGIIMTRDENVPPIVEFGPEYFDGLI---IKSGESLRIK 27979
Query: 1069 CAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
V+G P P+V W K+ +EI + IT+ G +L +R + G YT A N G
Sbjct: 27980 ALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGS 28039
Query: 1129 ALAECKLEVR 1138
A AE K++V+
Sbjct: 28040 AKAEIKVKVQ 28049
Score = 90.1 bits (222), Expect = 1e-17
Identities = 105/434 (24%), Positives = 163/434 (37%), Gaps = 37/434 (8%)
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
E ++ NA G +++ P + P++++ DVT T+ W+PP G +
Sbjct: 17580 EYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVI 17637
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
Y+VE + W ++ + + +L G +FRV N G P V
Sbjct: 17638 NYIVEKQDTRKDTWGVVSSGS-SKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV 17696
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
+ + P P T I + ++ +P P + + V V
Sbjct: 17697 AKHKFSPPSP---PGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 17753
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPINVMV 941
+ + F R + YE V EN+ + R ++ GPPIN +
Sbjct: 17754 KTPIADLKF-RVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKL 17812
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEW--FNVYERNRHTSCTVSDLIVG 999
K+ A + W P DG S I+GY V+ T +W N E R + V LI G
Sbjct: 17813 KDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 17872
Query: 1000 NEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVV 1059
NEY FR+ NI G + R L + K D P+ + R V
Sbjct: 17873 NEYRFRIKAANIVG--------EGEPRELAESVIAK-------DILHPPEVELDVTCRDV 17917
Query: 1060 VA---GYSAALNCAVRGHPKPKVVWMK-NKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ G + + V+G P+P + W K K+ +RE LI + V L I+ D
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADH 17976
Query: 1116 GTYTCRAVNELGEA 1129
G Y A N G A
Sbjct: 17977 GKYIISAKNSSGHA 17990
Score = 89.4 bits (220), Expect = 2e-17
Identities = 103/435 (23%), Positives = 167/435 (38%), Gaps = 40/435 (9%)
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
YE+++ NA+G + ++ + P P+ + VT TL WRPP G I
Sbjct: 26943 YELKLR--NAMGSASATIRVQILDKPGPPGGPIEF--KTVTAEKITLLWRPPADDGGAKI 26998
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE W + E +E C T + G +FRV VN G EP
Sbjct: 26999 THYIVEKRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSV 27057
Query: 829 VTIREIAEPPKIRLPRHLRQT-------YIRKVGEQLNLVVPF--QGKPRPQVVWTKG-G 878
V P +P + T + R + + + + + + + + + W K
Sbjct: 27058 VAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLK 27117
Query: 879 APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN 938
+ +R V ++ + R A + +G+ S E K I + GPP
Sbjct: 27118 ETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI-----DPPGPPAK 27172
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSDL 996
+ + + ++ + W P DG S + GY V+ + EW V + R T VS+L
Sbjct: 27173 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 27232
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G YYFRV N G + +++ P + K D AP+ +
Sbjct: 27233 KPGVNYYFRVSAVNCAGQGEPIEMNE-------------PVQAK--DILEAPEIDLDVAL 27277
Query: 1057 RVVV---AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPF 1113
R V AG + +G P P V W K++ + D ++ I N L I + +
Sbjct: 27278 RTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN 27337
Query: 1114 DAGTYTCRAVNELGE 1128
D G Y N +GE
Sbjct: 27338 DTGKYILTIENGVGE 27352
Score = 89.4 bits (220), Expect = 2e-17
Identities = 134/655 (20%), Positives = 251/655 (38%), Gaps = 101/655 (15%)
Query: 23 KEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPD 82
K++ K + ++ P+ P + +P V + +V + A K G+
Sbjct: 32825 KKSDQKTTESTVTRKTEPKAPEPISSKP--VIVTGLQDTTVSSDSVAKFAVKATGEP--- 32879
Query: 83 KPTIKWFK-GKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAK 141
+PT W K GK + G K +K S D+G + LE+
Sbjct: 32880 RPTAIWTKDGKAITQGGK------YKLSE-------------------DKGGFFLEIHKT 32914
Query: 142 DTCDSCGFNIDVEAPRQDASGQ---SLESFKRTSEKKSDTAGELDFSGLLKKREVVEEE- 197
DT DS + V+ S ++++ K T +K T + + +K+ VV+EE
Sbjct: 32915 DTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITP--QKKAVVQEEI 32972
Query: 198 ----------KKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKK 247
K + K + L + E ++L + + + + I + + + +
Sbjct: 32973 SQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSI--VHEEITKTSQ 33030
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
A EV+ A K ++ G ++ L I+ +KW NG E+ S +Y +
Sbjct: 33031 ASEEVRTHAEI-KAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNSEEYRYGVS 33088
Query: 308 GKKRILTINKCTLADDAAYEVAVKDE----KCFTELF----VKEPPVLIVTPLEDQQVFV 359
G + LTI + + D+ K + KC +L + + P I P Q +
Sbjct: 33089 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RSQNINE 33147
Query: 360 GDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGR 418
G V E+S E ++ W K+ + + S + + + L + D G+
Sbjct: 33148 GQNVLFTCEISGEPSPEIEWFKNNLPI----SISSNVSISRSRNVYSLEIRNASVSDSGK 33203
Query: 419 YQVITNG--GQCEAEL------IVEEKQLE-VLQDIADLTVKAS------EQAVFKCEVS 463
Y + GQC A +VEE E VL+ D +++ S + + K E S
Sbjct: 33204 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 33263
Query: 464 DEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG--DYTFVPDGYALSLSA 521
+ + E++ + ++ + + ++ G + T + + L A
Sbjct: 33264 FSSFSSSSASSMTEMKFAS-MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKA 33322
Query: 522 KLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW-LK 580
+ + K+E +P I + G L + + TGEP P TW
Sbjct: 33323 GIRGIPPKIEALPSD-----------------ISIDEGKVLTVACAFTGEPTPEVTWSCG 33365
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
G ++ + +GR IE D ++ +I Q++D G YT+ + N G D A++ + +
Sbjct: 33366 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 89.0 bits (219), Expect = 2e-17
Identities = 209/937 (22%), Positives = 336/937 (35%), Gaps = 129/937 (13%)
Query: 250 VEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPD-LTLKWFKNGQEIKPSSKYV----F 304
V++K+ F KL+ + V G +L I + ++W K +E+ S+ +
Sbjct: 5604 VKLKEPPRFVSKLN-SLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFV 5662
Query: 305 ENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE----LFVKEPPVLIVTPLEDQQVFVG 360
ENV L K A+ Y +K++ E L V EP V IV V VG
Sbjct: 5663 ENVAT---LQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAV-IVEKAGPMTVTVG 5718
Query: 361 DRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY 419
+ + +V+ V W KDG LT K + + K IL V ++D G Y
Sbjct: 5719 ETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRIL---SVERQDAGTY 5774
Query: 420 --QVITNGGQCEAELIVEEKQLEV----LQDIADLTVKASEQAVFKCEVSDEK-VTGKWY 472
QV N G+ +V+ V + + + + +C+V+ ++ W+
Sbjct: 5775 TFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWF 5834
Query: 473 KNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEY 532
++ + + L ++ + D G+YT V A S +
Sbjct: 5835 HEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRA--------V 5886
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
+ QEPP S + V+ G + I G PP W +G + R
Sbjct: 5887 LTVQEPP------SFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGD-RC 5939
Query: 593 RIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGE 652
I + + + G YT V+N G+ + L V + + + SV
Sbjct: 5940 NIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEP 5999
Query: 653 DWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-----TTYESTKMIEGI 707
+I++ Y G P+ S W K F + T T E T ++E I
Sbjct: 6000 GKSIIL--ESTYTGTLPI-----------SVTWKKDGFNITTSEKCNIVTTEKTCILE-I 6045
Query: 708 LYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
L + A + + T EP + + E P G
Sbjct: 6046 LNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTE-----------LEPLEAAVG- 6093
Query: 768 IDGYLVEYCLEGSEE----WVPANTE----PVERCGFTVKNLPTGARILFRVVGVNIAGR 819
D ++ + G+ E W +T+ P R FT N+ T ++F V +N +G
Sbjct: 6094 -DSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFT-NNVAT---LVFNKVNINDSGE 6148
Query: 820 -----SEPATLAQPVTIREIAE---PPKI-RLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
A T+ I E PP R + + QT VG + L G
Sbjct: 6149 YTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQT----VGLPVTLTCRLNGSAPI 6204
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVR--QAARSDSGEYELSVQIENMKDTATIRIR 928
QV W + G L +++TS D V ++ Q S SG+Y S +++ R+
Sbjct: 6205 QVCWYRDGVLLRDDE-NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT 6263
Query: 929 VVEKAGPPI----NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYE 984
E P V + + G +A E ++ M K +K+ N
Sbjct: 6264 AREPKKSPFFDIKPVSIDVIAGESADFECHVT----GAQPMRITWSKDNKEIRPGGNY-- 6317
Query: 985 RNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDF 1044
T++ VGN + R+ G DS + + + KE
Sbjct: 6318 -------TIT--CVGNTPHLRILK---VGKGDSGQYTCQATNDVGKDMCSAQLSVKE--- 6362
Query: 1045 RMAPKFLTPL-IDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
PKF+ L +V G S L C + G P+ KV W +N E+ E K+ ++ V
Sbjct: 6363 --PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVA 6420
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
L I S D+G Y C A N +G+A L V+ P
Sbjct: 6421 LLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP 6457
Score = 88.2 bits (217), Expect = 4e-17
Identities = 106/434 (24%), Positives = 168/434 (38%), Gaps = 44/434 (10%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ AVN +G + M P P+ E V+ TL W PP G I Y+
Sbjct: 16196 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKF--ESVSADQMTLSWFPPKDDGGSKITNYV 16253
Query: 773 VEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR 832
+E + WV ++EP E C +T+ L G +FR++ N G EP ++P T R
Sbjct: 16254 IEKREANRKTWVHVSSEPKE-CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD-SEPETAR 16311
Query: 833 EIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-FQGKPRPQVVWTKGGAPLDTSRVHVRTS 891
+ P P + + + +N P + G W + DT+ +
Sbjct: 16312 NLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLE---MKDTTSKRWKRV 16366
Query: 892 DFDTVFFV------RQAARSDSGEYELSVQIENM---------KDTATIRIRVVEKAGPP 936
+ D + + + + +Y+ V N D AT R + GPP
Sbjct: 16367 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP-GPP 16425
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSD 995
V + ++A +EW P DG S++ GY V+ ++ EW ++ R T V+
Sbjct: 16426 FP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTG 16484
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G Y FRV NI G+ + PG + E K+ + +
Sbjct: 16485 LKEGAFYKFRVRAVNIAGIGE-PGEVTDV------------IEMKDRLVSPDLQLDASVR 16531
Query: 1056 DRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
DR+VV AG + V G P P V W N+ + ++ T ++ I+
Sbjct: 16532 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSH 16589
Query: 1115 AGTYTCRAVNELGE 1128
G Y+ A NE GE
Sbjct: 16590 QGVYSLLAKNEAGE 16603
Score = 88.2 bits (217), Expect = 4e-17
Identities = 118/461 (25%), Positives = 169/461 (36%), Gaps = 66/461 (14%)
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRI 763
I+G Y +R A N G +N K P P+ V VT +L W PP +
Sbjct: 23691 IDGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQ--VTGVTSEKCSLTWSPPLQD 23746
Query: 764 GAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPA 823
G I Y+VE W +E V V L G +FR++ VN G EP
Sbjct: 23747 GGSDISHYVVEKRETSRLAWTVVASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPL 23805
Query: 824 TLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG--------------EQLNLVVPFQGKPR 869
A + P P+ L T I K E + +V + + R
Sbjct: 23806 ESAPVLMKNPFVLPGP---PKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV--EKRDR 23860
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT-----AT 924
+ W K + R+ T +R ++ EYE V EN AT
Sbjct: 23861 SGIRWIK----CNKRRI--------TDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 23908
Query: 925 IRIRVVE---KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEW 979
+ + + K GPP N + + + + W P DG SEI+GY V+ KAD++ +
Sbjct: 23909 VYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQI 23968
Query: 980 FNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEY 1039
R T +S L EY RV N GL ++ V P
Sbjct: 23969 VTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV---------------PGTV 24013
Query: 1040 KEHDFRMAPKFLTPLIDR---VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLI 1096
K D AP+ R VV AG SA ++ +G P P++ W + + E + K I
Sbjct: 24014 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQI 24071
Query: 1097 TNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+I DAG Y + N G A ++V
Sbjct: 24072 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 24112
Score = 87.8 bits (216), Expect = 5e-17
Identities = 93/420 (22%), Positives = 167/420 (39%), Gaps = 32/420 (7%)
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
AK+ V+ + + QV + + E+++ D+ W+K+G EI + + V
Sbjct: 3138 AKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYV 3197
Query: 308 GKKRI--LTINKCTLADDAAYEVAVKDEKCFTELFVKEP-PVLIVTPLEDQQVFVGDRVE 364
++RI + I++ +D Y + L+V P P ++ L+ V G
Sbjct: 3198 VERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPAR 3257
Query: 365 MAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQED-------- 415
+S ++ W K+ E FK + F DG+ + L+ + ED
Sbjct: 3258 FCAVISGRPQPKISWYKE--EQLLSTGFKCK--FLHDGQEYTLLLIEAFPEDAAVYTCEA 3313
Query: 416 RGRYQVITNGGQCEAEL---IVEEKQLEV-----LQDIADLTVKASEQAVFKCEVSDEKV 467
+ Y V T E+ + ++++ V + + D + A F+C VS +
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3373
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNF-L 526
WY +++PS+ ++ ++L I + PEDEG YTFV +S+ N L
Sbjct: 3374 KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Query: 527 EIKVEYVPKQEPPKIHLDCSG----KTSENAIVVVAGNKLRLDVSITGEPPPVATWLK-G 581
E + ++ +I ++ K + V G+ + I P W K G
Sbjct: 3434 EAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 3493
Query: 582 DEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDP 641
E++ + + R K + SS I Q D G YT K +N G + L V + P
Sbjct: 3494 REIYESDKCSIRSSKYI--SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 3551
Score = 87.4 bits (215), Expect = 7e-17
Identities = 103/433 (23%), Positives = 161/433 (37%), Gaps = 50/433 (11%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++N K P P+ ++ VT TL W+PP + G I Y+VE
Sbjct: 22618 AKNVAGERSVTVNVKVLDRPGPPEGPV--VISGVTAEKCTLAWKPPLQDGGSDIINYIVE 22675
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPV 829
W + V+ V L G FR++ VN G SEP P
Sbjct: 22676 RRETSRLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPF 22734
Query: 830 TIREIAEPPKIRLPRHLRQTYI----RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR 885
+ + + P++ + G L + + + + WT R
Sbjct: 22735 VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT---------R 22785
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPI 937
H R +R ++ +YE V EN + + K GPP
Sbjct: 22786 CHKRLIG---ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN 22842
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSD 995
N V ++ ++ + W P DG EI GY V+K D EW T+ V
Sbjct: 22843 NPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEK 22902
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L+ +EY FR+ N G+ + V I + E + D + L +I
Sbjct: 22903 LLEKHEYNFRICAINKAGVGEHADVPGPI-------IVEEKLEAPDIDLDLE---LRKII 22952
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRPSPFD 1114
+ + AG S L ++G P P+V W K EIR+ +T ++ ++ N+ R +D
Sbjct: 22953 N--IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNR---YD 23007
Query: 1115 AGTYTCRAVNELG 1127
+G YT N G
Sbjct: 23008 SGKYTLTLENSSG 23020
Score = 87.4 bits (215), Expect = 7e-17
Identities = 98/404 (24%), Positives = 147/404 (36%), Gaps = 63/404 (15%)
Query: 713 VFAVNAIGVSQPSMNT----KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
V A N+ G + +++ KP P+ P ++V+ + W PP G I
Sbjct: 24384 VTATNSAGTATENLSVIVLEKPGPPVGPVR------FDEVSADFVVISWEPPAYTGGCQI 24437
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE + W + V R + L TG FR+ N G+S P
Sbjct: 24438 SNYIVEKRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV 24496
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV---------------VPFQGKPRPQVV 873
+ EP P ++ + + LV + K + ++
Sbjct: 24497 IVQYPFKEPGPPGTP------FVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 24550
Query: 874 WTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM----KDTATIRIR 928
W K ++ ++ + F T D G EYE V EN+ K +
Sbjct: 24551 WVK------LNKTPIQDTKFKTTGL-------DEGLEYEFKVSAENIVGIGKPSKVSECF 24597
Query: 929 VV-EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN- 986
V + PP + N ++W+ P DG S+I GY V+K D W N
Sbjct: 24598 VARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 24657
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
T TVS L+ Y FRV N G P S IT + E + +
Sbjct: 24658 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGA-------ITARD-EIDAPNASL 24709
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRE 1090
PK+ + VV AG + L +RG P P VVW K+ E+ E
Sbjct: 24710 DPKYKDVI---VVHAGETFVLEADIRGKPIPDVVWSKDGKELEE 24750
Score = 86.7 bits (213), Expect = 1e-16
Identities = 91/398 (22%), Positives = 151/398 (37%), Gaps = 28/398 (7%)
Query: 633 LQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV 692
L +D P P + IT L W P Y GG +T Y+VE++ + RW+K NF
Sbjct: 21354 LDPIDPPGKPVPLNIT---RHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSN 21410
Query: 693 FTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT 752
E + + + E YE RV A NA G P + E + V+ T
Sbjct: 21411 ILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDT 21470
Query: 753 TTLKWRPPNRIGA--GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
LK R+ A G +E+ +G E A E ++ F+ + + R
Sbjct: 21471 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE-IKIADFSTNLVNKDS--TRR 21527
Query: 811 VVGVNIAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKV-----------GEQL 858
G + P A+ + ++ + P P + + K G ++
Sbjct: 21528 DSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 21587
Query: 859 NLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN 918
+ + Q + ++ WT + + +++ V + R A + G E
Sbjct: 21588 DHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG------EP 21640
Query: 919 MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTME 978
++ + + PP N V + + +V W P DG SEI+ Y V++ DK
Sbjct: 21641 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 21700
Query: 979 WFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
W ++ VS L G+EY FR+ EN G+S
Sbjct: 21701 WIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 21738
Score = 86.7 bits (213), Expect = 1e-16
Identities = 227/1140 (19%), Positives = 382/1140 (33%), Gaps = 202/1140 (17%)
Query: 83 KPT--IKWF-KGKWLELGSK------SGA-RFSFKESHNSASNVYTVELHIGKVVLGDRG 132
KPT +KW+ G L+ SK SG + H S Y K D
Sbjct: 32400 KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASD-- 32457
Query: 133 YYRLEVKAKDTCDSCGFNIDVEAPRQ------DASGQSLESFKRTSEKKSDTAGELDFSG 186
Y L+V D D E PR ++ SFK+TSE ++ ++ S
Sbjct: 32458 YATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQ 32517
Query: 187 LLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLK 246
+ + RE + + + + + E +KS KI T +L + +
Sbjct: 32518 MTETRESLSSYEHSASAEMKSAALEEKSLE-----EKSTTRKIK----TTLAARILTKPR 32568
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFEN 306
V +SA F+ D +P T+ W + GQ + S+++
Sbjct: 32569 SMTVYEGESARFSCDTD-----------------GEPVPTVTWLRKGQVLSTSARHQVTT 32611
Query: 307 VGKKRILTINKCTLADDAAYEVAV-----KDEKCFTELFVKEPPVLIVTPLEDQQVFVGD 361
K I+ +D+ Y V V K E FT K + ++ V
Sbjct: 32612 TKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK-------ARVTEKAVTSPP 32664
Query: 362 RVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
RV+ + ++ K+ R K H S + +V
Sbjct: 32665 RVKSPEP---------------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKV 32709
Query: 422 ITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPS 481
+ I + + E ++IA LT + EV+ WYK+G +++ +
Sbjct: 32710 QHLPVSAPPK-ITQFLKAEASKEIAKLTCVVESSVLRAKEVT-------WYKDGKKLKEN 32761
Query: 482 KRITISH-VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE----------IKV 530
+ ++L I+++ D+G+Y G + L F+ K+
Sbjct: 32762 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 32821
Query: 531 EYVPKQEPPKIHLDCSGKTSENAI-------VVVAG---------NKLRLDVSITGEPPP 574
K + + KT A V+V G + + V TGEP P
Sbjct: 32822 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 32881
Query: 575 VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
A W K + T G+ ++ + I D G YT V N G +S L
Sbjct: 32882 TAIWTKDGKAITQG-GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLT 32940
Query: 635 VVDVPDPPEAVRITS------VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKL 688
+ + D EA ++++ + A++ E K + ++ + SQ + L
Sbjct: 32941 IKAIKDT-EAQKVSTQKTSEITPQKKAVVQEEISQ----KALRSEEIKMSEAKSQEKLAL 32995
Query: 689 NFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
E E K E + SQ S K F +E
Sbjct: 32996 KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQR 33055
Query: 743 LIVEDVTDTTTTLKW---------RPPNRIGAGGIDGYLV----EYCLEGSEEWVPANTE 789
L+++ T +KW R G G D L + EG + E
Sbjct: 33056 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 33115
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
+ +C + + T ++ L PA ++QP R
Sbjct: 33116 GIVKCQYDL----TLSKEL----------SDAPAFISQP------------------RSQ 33143
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSG 908
I + G+ + G+P P++ W K P+ +S V + S +R A+ SDSG
Sbjct: 33144 NINE-GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 33202
Query: 909 EYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
+Y + + + +AT + V+ P +V G +L
Sbjct: 33203 KYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL----------QGSFSSQS 33252
Query: 969 VQKADKKTMEWFNVYERNRHTSCT--------VSDLIVGNEYYFRVYTENICGLSDSPGV 1020
VQ + K F+ + + +S T + E + + + + G+S+ +
Sbjct: 33253 VQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQL 33312
Query: 1021 SKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVV 1080
+T+++LK GI P PK D + G + CA G P P+V
Sbjct: 33313 ESSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 33361
Query: 1081 WM--KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
W K+ +E +F I N + TL I D G YT NE G A + +R
Sbjct: 33362 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 33421
Score = 84.7 bits (208), Expect = 4e-16
Identities = 109/433 (25%), Positives = 158/433 (36%), Gaps = 52/433 (12%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G ++N K P + PL + +T +L W P G ID Y+VE
Sbjct: 25866 NVAGTRSVAVNCKVLDKPGPPAGPLE--INGLTAEKCSLSWGRPQEDGGADIDYYIVEKR 25923
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
W E ++ V L G +FRV GVN G EP + V I+ +
Sbjct: 25924 ETSHLAWTICEGE-LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKALDP 25979
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---- 892
P L T + K E + L RP+ + GG+ + + R +
Sbjct: 25980 FTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERREKNSLRW 26029
Query: 893 --------FDTVFFVRQAARSDSGEYELSVQIEN-----MKDTATIRIRVVEKA---GPP 936
+D V+ + EYE V EN + + IR + PP
Sbjct: 26030 VRVNKKPVYD--LRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPP 26087
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ + T + W P DG + I GY V+ +W + R T T+S L
Sbjct: 26088 SKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 26147
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G EY FRV + N G SD S +I K +E F + + LI
Sbjct: 26148 TTGAEYVFRVKSVNKVGASDPSDSSD--PQIAKE-------REEEPLFDIDSEMRKTLI- 26197
Query: 1057 RVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAG 1116
V AG S + RG P P V+W K ++R + + +L I + D+G
Sbjct: 26198 --VKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIENANRNDSG 26253
Query: 1117 TYTCRAVNELGEA 1129
YT N L A
Sbjct: 26254 KYTLTIQNVLSAA 26266
Score = 84.3 bits (207), Expect = 6e-16
Identities = 200/926 (21%), Positives = 340/926 (36%), Gaps = 134/926 (14%)
Query: 286 TLKWFK-NGQEIKPSSKYVFENV--GKKRILTINKCTLADDAAYEVAVKDEKCFTELFV- 341
T KW + N + IK V E V K+ +L + A + V + +E V
Sbjct: 14328 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVR-------AVNAIGVSEPSEISENVVA 14380
Query: 342 KEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQV---MWMKDGVELTREDSFKARYRFK 398
K+P LE + V + ++++ V V W KDG E+ D R K
Sbjct: 14381 KDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD----RLTMK 14436
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
D L V+ D G Y + A + K + + D +KAS+
Sbjct: 14437 NDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD--IKASDITKS 14494
Query: 459 KCEVSDEKVTGKWYKNGVEV--------RPSKRITISHVGRFHKL--VIDDVRPEDEGDY 508
C+++ E + G + +R I + +KL + D+ P G+Y
Sbjct: 14495 SCKLTWEPPE---FDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPN--GEY 14549
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYV---PKQEP-PKIHLDCSGKTSENAIVVVAGNKLRL 564
F A++ ++E+K + PKQ P P + ++ T+E
Sbjct: 14550 FFRVK--AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA------------ 14595
Query: 565 DVSITGEPPPV--ATWLKGDEVFTTTEGRTRI----EKRVDCSSFVIESAQREDEGRYTI 618
++IT +PP + + G + +G R E V ++ + + E ++ +
Sbjct: 14596 -MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRV 14654
Query: 619 KVTNPVG---EDVASIFLQVVDVPDPPEAVRITSV---------------GEDWAILVWE 660
+ N G A+ + VD D P+ + TS+ G + + W
Sbjct: 14655 RAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWI 14714
Query: 661 PP----MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL-------- 708
+ + K LV R+K Q + + +++K E L
Sbjct: 14715 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 14774
Query: 709 ----YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y ++V N G+++ P P++ + ED+ T+ KW PP G
Sbjct: 14775 DHGLYMIKV--ENDHGIAKAPCTVSVLDTPGP---PINFVFEDIRKTSVLCKWEPPLDDG 14829
Query: 765 AGGIDGYLVEYC--LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEP 822
I Y +E + EW+ T + C ++V L G LFRV N G P
Sbjct: 14830 GSEIINYTLEKKDKTKPDSEWIVV-TSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 14888
Query: 823 ATLAQPVTIREIAEPP----KIRLPRHLRQTYIRKVGEQLNLVVPFQG-----KPRPQVV 873
+++P+ ++ PP K + + + K E + P G +
Sbjct: 14889 C-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTH 14947
Query: 874 WTK-GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W++ + L+ + +V + R A + +G + S D T +
Sbjct: 14948 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP----SDPKTAH-DPISP 15002
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSC 991
GPPI V + T +EW+ P +G EI+GYFV K T EW E+ +
Sbjct: 15003 PGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQY 15061
Query: 992 TVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
TV ++ G +Y RV N G PG ++ +P E + ++ K
Sbjct: 15062 TVKEIREGADYKLRVSAVNAAG-EGPPGETQPVT-------VAEPQEPPAVELDVSVKGG 15113
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
++AG + + V G P P VW K + E+ +D + +I N L I+
Sbjct: 15114 IQ-----IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDAL 15167
Query: 1112 PFDAGTYTCRAVNELGEALAECKLEV 1137
D G Y A N G A ++EV
Sbjct: 15168 RKDHGRYVITATNSCGSKFAAARVEV 15193
Score = 84.3 bits (207), Expect = 6e-16
Identities = 117/447 (26%), Positives = 169/447 (37%), Gaps = 58/447 (12%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++ N K P PL V +VT L W PP G ID Y+V+
Sbjct: 21536 ATNPGGFAKHIFNVKVLDRPGPPEGPL--AVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 21593
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
W +E V+ V L G +FRV+ VN G EP ++PV
Sbjct: 21594 KRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-SEPVLAVNP 21651
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFD 894
PP P++ T I K + +V G P + GG+ + V R
Sbjct: 21652 YGPPDP--PKNPEVTTITK-----DSMVVCWGHPD-----SDGGSEIINYIVERRDKAGQ 21699
Query: 895 ----------TVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPP 936
T + + ++ EYE + EN + V K GPP
Sbjct: 21700 RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPP 21759
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVS 994
N V + ++ + W P DG SEI GY V+ A + EW V + TS T++
Sbjct: 21760 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 21819
Query: 995 DLIVGNEYYFRVYTENICGLSDS---PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
L EY R+Y N GL + PG K R+L I + D R K +
Sbjct: 21820 GLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIEL------DADLR---KVV 21870
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRP 1110
T + A + L ++G P P+V W ++ E + T +Y ++ N+ R
Sbjct: 21871 T------IRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNR- 21923
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
FD+G Y N G A + V
Sbjct: 21924 --FDSGKYILTVENSSGSKSAFVNVRV 21948
Score = 84.3 bits (207), Expect = 6e-16
Identities = 106/412 (25%), Positives = 143/412 (34%), Gaps = 70/412 (16%)
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
++T TL W P G I Y++E W + E +T L G
Sbjct: 28063 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNE 28121
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRLPRHLRQTYIRKV--------G 855
FRV VN G P + PV + + + P I P ++ I G
Sbjct: 28122 YQFRVSAVNKFGVGRPLD-SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGG 28180
Query: 856 EQLNLVVPFQGKPRPQVVWTK--GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
++ + + + + W K P+ +R V ++ EYE
Sbjct: 28181 SEIQQYI-LERREKKSTRWVKVISKRPISETRFKV-------------TGLTEGNEYEFH 28226
Query: 914 VQIENMKDTAT-------IRIRV-VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
V EN I+ R V GPP V V + T +EW P DG EI+
Sbjct: 28227 VMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 28286
Query: 966 GYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS------- 1017
GY ++ +W V E T TV+DL G EY FRV N G DS
Sbjct: 28287 GYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTI 28346
Query: 1018 PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKP 1077
V + TA L FK VV AG S L A +G P P
Sbjct: 28347 KAVDRLTAPELDIDANFKQ-------------------THVVRAGASIRLFIAYQGRPTP 28387
Query: 1078 KVVWMK--NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
VW K + + +R D I TL + + DAG YT N G
Sbjct: 28388 TAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNRNDAGKYTLTVENNSG 28435
Score = 84.0 bits (206), Expect = 8e-16
Identities = 108/447 (24%), Positives = 166/447 (37%), Gaps = 71/447 (15%)
Query: 720 GVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEG 779
G Q ++ +P P+ P S ++VT + W+PP G I Y++E G
Sbjct: 16902 GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG 16955
Query: 780 SEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK 839
+ W+P T + V L G +FR+ N+ G S+P + + +
Sbjct: 16956 KDVWMPV-TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP------LVSDSMKAKDR 17008
Query: 840 IRLPRHLRQTYIRKVGEQLNLVV---PFQG-KPRPQVV------WTKGGAPLDTSRVHVR 889
R+P Q + +V + LV P G KP + +K A + +H
Sbjct: 17009 FRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPY 17068
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRV-----VEKAGPPINVMV 941
T R + +YE V EN + D + V + K PP+N
Sbjct: 17069 TK-------FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEA 17121
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT--SCT-----VS 994
+ + + WQ P+ DG S+I+GY V+ EW R HT SC V+
Sbjct: 17122 IDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW----RRANHTPESCPETKYKVT 17177
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL--- 1051
L G Y FRV N G SD V + P K+ R+ P L
Sbjct: 17178 GLRDGQTYKFRVLAVNAAGESDPAHVPE-------------PVLVKD---RLEPPELILD 17221
Query: 1052 -TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110
++ + G + L+ ++G P PKV W K + + +T L IR
Sbjct: 17222 ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNA 17279
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D G Y+ N G K+ V
Sbjct: 17280 AHEDGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 84.0 bits (206), Expect = 8e-16
Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 24/234 (10%)
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++ R A ++ G + V +E + ++ E PP V + +V T+A + W+
Sbjct: 24184 IYYFRVMAENEFG---VGVPVETVD-----AVKAAEPPSPPGKVTLTDVSQTSASLMWEK 24235
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG S ++GY V+ K T +W V E ++ + V+ L G EY FRV N G S
Sbjct: 24236 PEHDGGSRVLGYVVEMQPKGTEKWSIVAE-SKVCNAVVTGLSSGQEYQFRVKAYNEKGKS 24294
Query: 1016 DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHP 1075
D R+L + K D + P P + AG + V G P
Sbjct: 24295 DP--------RVLGVPVIAK-------DLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRP 24339
Query: 1076 KPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
+P + W+K+ +++ + + L+I+ + D G YT A N G A
Sbjct: 24340 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 24393
Score = 82.8 bits (203), Expect = 2e-15
Identities = 100/415 (24%), Positives = 149/415 (35%), Gaps = 52/415 (12%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ D+ +L W P G I Y+VE C +WV A V + V L G
Sbjct: 19001 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTKTSCRVGKLIPG 19059
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV---------- 854
+FRV N G SEP T + V P + P++ R T + K
Sbjct: 19060 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSE---PKNARVTKVNKDCIFVAWDRPD 19116
Query: 855 --GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
G + + K R ++W K L VR++++ V + EY
Sbjct: 19117 SDGGSPIIGYLIERKERNSLLWVKANDTL------VRSTEYPCAGLV------EGLEYSF 19164
Query: 913 SVQIENM-------KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
+ N K T + R+ PP V +V + + W PK DG S+I+
Sbjct: 19165 RIYALNKAGSSPPSKPTEYVTARM--PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKII 19222
Query: 966 GYFVQKADKKTMEWFNVYERNRHT---SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
GYFV+ +W T + L +Y FR +S P
Sbjct: 19223 GYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP-PSEPS 19281
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+ IL + D +A K L V AG + L+ V G P P V W
Sbjct: 19282 DPVTILAENVP------PRIDLSVAMKSLL-----TVKAGTNVCLDATVFGKPMPTVSWK 19330
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
K+ ++ + + + TL + + D+G YT A N G A KL+V
Sbjct: 19331 KDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 19385
Score = 82.8 bits (203), Expect = 2e-15
Identities = 92/405 (22%), Positives = 156/405 (38%), Gaps = 35/405 (8%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+++V+ + T+ W PP G I Y+VE S W + + V R + L TG
Sbjct: 25496 IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS-QAVARTSIKIVRLTTG 25554
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT-------YIRKVGEQ 857
+ FRV N G+S + + V + P P+ + T + V +
Sbjct: 25555 SEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDG 25614
Query: 858 LNLVVPF--QGKPRPQVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSV 914
+ V+ + + K R ++W+K L +++ V D ++ R A + +G + S
Sbjct: 25615 GSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSK 25674
Query: 915 QIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
E + + PP V + + ++W P DG ++I GY V++ +
Sbjct: 25675 SCEP--------VPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERREL 25726
Query: 975 KTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
W Y + T V++L Y FRV+ N P S++T I+
Sbjct: 25727 PDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEP--SESTGPIIVKDDV 25784
Query: 1034 FKPFEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDP 1092
P + FR D +VV AG +N + G P P + W K+ +EI E
Sbjct: 25785 EPPRVMMDVKFR----------DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 25834
Query: 1093 KFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG--EALAECKL 1135
+ I + L ++ D G Y N G CK+
Sbjct: 25835 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879
Score = 77.8 bits (190), Expect = 5e-14
Identities = 95/402 (23%), Positives = 156/402 (38%), Gaps = 45/402 (11%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ +V+ TL W PP G I Y++E W + E ++ C L G
Sbjct: 20481 ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQG 20539
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP----KIRLPRHLRQT----YIRKVGE 856
+FRV VN G+ EP ++PV + + PP K + + T + R V +
Sbjct: 20540 NEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 20598
Query: 857 QLNLVVPF--QGKPRPQVVWTKG-GAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + + + + + + W + P+ R V + + R +A + +G S
Sbjct: 20599 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 20658
Query: 914 VQIEN--MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
++ MKD A GPP N V + +A + W P DG EI GY V+
Sbjct: 20659 EASDSVLMKDAAY-------PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 20711
Query: 972 ADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILK 1029
W R T V DL +Y FR+ N G+ + P V + + +
Sbjct: 20712 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVER 20770
Query: 1030 TGITFKPFEYKEHDFRMAPKF-LTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKM 1086
MAP F L + R +V AG S + ++G P P+V W K+ +
Sbjct: 20771 ---------------EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 20815
Query: 1087 EIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
++ + I N + L I + +D G + N G+
Sbjct: 20816 NLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGK 20855
Score = 77.4 bits (189), Expect = 7e-14
Identities = 77/267 (28%), Positives = 117/267 (43%), Gaps = 21/267 (7%)
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV----KDEKCFTELFVKEP 344
W K+G I+ S K+ F GK R L I L+D Y + K++ +L V+E
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Query: 345 PVLIVTPLEDQQVFV-GDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
PV V LE++ V G + ++ E+++E V+W KDG + + R G
Sbjct: 11211 PVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDGKIVVEK---PGRIVPGVIGLM 11266
Query: 404 HILIFSDVVQEDRGRYQV-ITNGGQCEAELIVEEKQLEVLQD-----IADLTVKASEQAV 457
L +D D G Y V + N E V K +EV++D I D VK A+
Sbjct: 11267 RALTINDADDTDAGTYTVTVENANNLECSSCV--KVVEVIRDWLVKPIRDQHVKPKGTAI 11324
Query: 458 FKCEVSDEKVTGKWYKNGVEV--RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
F C+++ + KW+K E+ P+ + I G L I + PED +Y +G
Sbjct: 11325 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG- 11383
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIH 542
AKL E +VE + E I+
Sbjct: 11384 -KRYPAKLTLGEREVELLKPIEDVTIY 11409
Score = 77.4 bits (189), Expect = 7e-14
Identities = 139/622 (22%), Positives = 222/622 (35%), Gaps = 82/622 (13%)
Query: 563 RLDVSITGEPPPVATWLKGDEVFTTTEGRTRI-----EKRVDCSSFVIESAQRED----- 612
RLDV T + V WLK D +G +RI E R S F +E+ +
Sbjct: 28551 RLDVVDTSKSSAVLAWLKPDH-----DGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 28605
Query: 613 -------EGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITS------VGEDW 654
E + +K N G E +S+ ++ + + IT+ G +
Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 28665
Query: 655 AILVWEPPMYDGGKP---VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
I V P+ G+P VT L E + K + R + T T + + + Y +
Sbjct: 28666 TIDV---PI--SGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 28720
Query: 712 RVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
+ N GV S+ P + P+ V V+ + L W P G I Y
Sbjct: 28721 TL--ENTAGVKTFSVTVVVIGRPGPVTGPIE--VSSVSAESCVLSWGEPKDGGGTEITNY 28776
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
+VE G+ W N+ V+R V +L FRV N G S+P A P+
Sbjct: 28777 IVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESA-PIIA 28834
Query: 832 REIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF------------QGKPRPQVVWTKGGA 879
PP P ++ + P+ + K R ++W K
Sbjct: 28835 EHPFVPPSA--PTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVK--- 28889
Query: 880 PLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINV 939
++V ++ V + Y L+ + A+ I P
Sbjct: 28890 ---ENKVPCLECNYKVTGLV-EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP 28945
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM---EWFNV-YERNRHTSCTVSD 995
V +V + + W AP DG S+++GY +++ + W Y TV+
Sbjct: 28946 EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTA 29005
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G+ Y FRV +N G+ +SK + TG EY + + L+
Sbjct: 29006 LSEGDTYEFRVLAKNAAGV-----ISKGSE---STGPVTCRDEYAPPKAELDARLHGDLV 29057
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ AG L+ AV G P+PK++W K E+ K + T I+ D+
Sbjct: 29058 --TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 29115
Query: 1116 GTYTCRAVNELGEALAECKLEV 1137
G YT N G ++V
Sbjct: 29116 GKYTLTVKNASGTKAVSVMVKV 29137
Score = 77.0 bits (188), Expect = 9e-14
Identities = 53/204 (25%), Positives = 88/204 (43%), Gaps = 16/204 (7%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++ E+ PP + + +V + + W+ P+ DG S I+GY V+ K + +W
Sbjct: 22043 VKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC-ATV 22101
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ T T++ LI G EY FRV +N G+SD R L + K D +
Sbjct: 22102 KVTEATITGLIQGEEYSFRVSAQNEKGISDP--------RQLSVPVIAK-------DLVI 22146
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P F V+AG ++ G P P V W K+ + +++ + + + L
Sbjct: 22147 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 22206
Query: 1107 IRRPSPFDAGTYTCRAVNELGEAL 1130
I+ D G Y + N GEA+
Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAI 22230
Score = 74.7 bits (182), Expect = 5e-13
Identities = 97/436 (22%), Positives = 155/436 (35%), Gaps = 49/436 (11%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ A N+ G ++ K P P + + + L W PP G I Y+
Sbjct: 19368 ITAENSSGSKSATIKLKVLDKPGP---PASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424
Query: 773 VEYCLEGSEEWVPAN-TEPVERCGFTVKNLPTGARILFRVVGVNIAGR-----SEPATLA 826
V+ W + T P+ C +V+ L G FR+ N G +EPA
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSC--SVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAK 19482
Query: 827 QPVTIREIAEPPKIR--LPRHLRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLD 882
P +PP I H+ ++ + + + + + + V WTK ++
Sbjct: 19483 NPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VN 19538
Query: 883 TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMK--------DTATIRIRVVEKAG 934
+ RT ++ + EYE V N A G
Sbjct: 19539 RKPIIERT--------LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPG 19590
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEWFNVYERNRHTSCT 992
PP V + ++ + W P DG S I+GY V+ +AD N+ + + T
Sbjct: 19591 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFE 19650
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
V+ L+ +Y FRVY N G SD V + I P + D R
Sbjct: 19651 VTGLMEDTQYQFRVYAVNKIGYSDPSDVPD---KHYPKDILIPPEGELDADLRKT----- 19702
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
++ AG + L V+G P PK+ W K + +R+ I + L +
Sbjct: 19703 ----LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 19758
Query: 1113 FDAGTYTCRAVNELGE 1128
+DAG Y N G+
Sbjct: 19759 YDAGKYILTLENSCGK 19774
Score = 73.6 bits (179), Expect = 1e-12
Identities = 105/414 (25%), Positives = 152/414 (36%), Gaps = 56/414 (13%)
Query: 742 HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNL 801
+L + DV+ T+ W PP G I Y++E C W + V G TV L
Sbjct: 18302 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRL 18360
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G +FRV N G P T ++PV + + P P + KV ++ V
Sbjct: 18361 IEGNEYIFRVRAENKIGTGPP-TESKPVIAKTKYDKPGRPDPPE-----VTKVSKEEMTV 18414
Query: 862 V----PFQG-----------KPRPQVVWT---KGGAPLDTSRVHVRTSDFDTVFFVRQAA 903
V + G K + W K P +V D + F V+
Sbjct: 18415 VWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAEN 18474
Query: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
GE L + KD +E GPP N V + + + W P DG +
Sbjct: 18475 EIGIGEPSLPSRPVVAKDP-------IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 18527
Query: 964 IMGYFVQK----ADKKTMEWF---NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
I+GY V+ AD E + N + TV+ L EY FRV +N G+
Sbjct: 18528 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 18587
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
+ + KP E E + L+ +V AG L VRG P
Sbjct: 18588 PAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGRPA 18635
Query: 1077 PKVVWMKNKME--IREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
PKV W K ++ +R+ L+ ++ N R D+G Y+ VN GE
Sbjct: 18636 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRD---DSGKYSLTLVNPAGE 18686
Score = 73.6 bits (179), Expect = 1e-12
Identities = 101/421 (23%), Positives = 155/421 (36%), Gaps = 60/421 (14%)
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLP 802
L V VT L W PP + G I Y++E W +TE V+ + V L
Sbjct: 24809 LKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE-VQALNYKVTKLL 24867
Query: 803 TGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP--------KIRLPRHLRQTYIRKV 854
G +FRV+ VN G EP + PVT +PP + T+ R V
Sbjct: 24868 PGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPV 24926
Query: 855 GEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ + + + + + V WTK T +R ++ YE
Sbjct: 24927 DDGGTEIEGYILEKRDKEGVRWTKCNKKTLTD------------LRLRVTGLTEGHSYEF 24974
Query: 913 SVQIENMKDTA-----TIRIRVVEKA---GPPINVMVKEVWGTNALVEWQAPKDDGNSEI 964
V EN ++ R + GPP N V + ++ + W P DG + +
Sbjct: 24975 RVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPV 25034
Query: 965 MGYFVQKADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDS---PG 1019
GY V+ + EW + TV+ L EY FR+ N G+ + PG
Sbjct: 25035 KGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPG 25094
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC--AVRGHPKP 1077
RI I + D R +VVV SA L ++G P+P
Sbjct: 25095 SVVAQERIEPPEIEL------DADLR-----------KVVVLRASATLRLFVTIKGRPEP 25137
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTL-NIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
+V W K + + + + +T+ +L + N+ R FD+G Y N G A +
Sbjct: 25138 EVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR---FDSGRYNLTLENNSGSKTAFVNVR 25194
Query: 1137 V 1137
V
Sbjct: 25195 V 25195
Score = 70.1 bits (170), Expect = 1e-11
Identities = 61/232 (26%), Positives = 96/232 (41%), Gaps = 25/232 (10%)
Query: 905 SDSGEYELSVQIENM-----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
S+ EY V EN T ++ E PP ++ + ++ + + W PK D
Sbjct: 20932 SEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHD 20991
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
G S+I GY ++ K + +W ++ + C V +L G EY F+V N G S +P
Sbjct: 20992 GGSKITGYVIEAQRKGSDQWTHI-TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS-APR 21049
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTPLIDRVVVA--GYSAALNCAVRGHPK 1076
S+ P KE M P+ L + ++V+A G + + V G PK
Sbjct: 21050 ESR-------------PVIVKEQT--MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPK 21094
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
P V W K +++ + LNI D+G Y A N +GE
Sbjct: 21095 PTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 21146
Score = 69.7 bits (169), Expect = 1e-11
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 31/279 (11%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K E+R + I ++ F LV+D+V D G YT + S K F+ ++
Sbjct: 22975 KWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLEN---SSGTKSAFVTVR 23029
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V P P ++L + T ++ VSIT EPP + K
Sbjct: 23030 VLDTPS---PPVNLKVTEITKDS-------------VSITWEPPLLDGGSKIKNYIVEKR 23073
Query: 590 GRTR-----IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF---LQVVDVPDP 641
TR + +S+ I+ Q + + N G + + ++V +VP P
Sbjct: 23074 EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQP 23133
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
P + + V + L W P +DGG + Y+VE + K S++W + + T
Sbjct: 23134 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVI--T 23191
Query: 702 KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP 740
+ +G Y RV AVN G S P P + EP
Sbjct: 23192 NLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 23230
Score = 69.3 bits (168), Expect = 2e-11
Identities = 81/305 (26%), Positives = 128/305 (41%), Gaps = 40/305 (13%)
Query: 429 EAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISH 488
E EL + +++ VL+ A L + + + + EV EK G + R I
Sbjct: 25106 EIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL---------TDRAQIEV 25156
Query: 489 VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
F LVID+V D G Y + + +K F+ ++V LD
Sbjct: 25157 TSSFTMLVIDNVTRFDSGRYNLTLEN---NSGSKTAFVNVRV------------LD---- 25197
Query: 549 TSENAIVVVAGNKLRLD-VSITGEPPPVATWLK-----GDEVFTTTEGRTRIEKRVDCSS 602
S +A V + +++ D V+++ EPP + K ++ TT + I ++
Sbjct: 25198 -SPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT 25256
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVW 659
F IE+ Q + + +N G + + + V V P PP V + V + A + W
Sbjct: 25257 FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 25316
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
E P DGG +TGY+VE + KGS++W E T + G Y RV AVN
Sbjct: 25317 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISG--LTAGEEYVFRVAAVNEK 25374
Query: 720 GVSQP 724
G S P
Sbjct: 25375 GRSDP 25379
Score = 68.2 bits (165), Expect = 4e-11
Identities = 79/289 (27%), Positives = 122/289 (42%), Gaps = 32/289 (11%)
Query: 340 FVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKK 399
FVKE +I+T E FVG VS A WMKDG + ++RF
Sbjct: 11117 FVKEIKDIILTESE----FVGSSAIFECLVSPSTAITTWMKDGSNIRE----SPKHRFIA 11168
Query: 400 DGKRHILIFSDVVQEDRGRYQVITNGGQCE----AELIVEEKQLEVLQDI-ADLTVKASE 454
DGK L DV D G Y + G E A+L+VEE + ++ + ++TV +
Sbjct: 11169 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ 11228
Query: 455 QAVFKCEVSDEKVTGKWYKNG-VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VP 512
CE++ E+ W K+G + V RI +G L I+D D G YT V
Sbjct: 11229 PLYLSCELNKERDV-VWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 11287
Query: 513 DGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEP 572
+ L S+ + +E+ +++ K P + D K AI D++ +
Sbjct: 11288 NANNLECSSCVKVVEVIRDWLVK--PIR---DQHVKPKGTAI-------FACDIA---KD 11332
Query: 573 PPVATWLKG-DEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
P W KG DE+ +T I + + I++A ED Y +++
Sbjct: 11333 TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 11381
Score = 68.2 bits (165), Expect = 4e-11
Identities = 106/473 (22%), Positives = 165/473 (34%), Gaps = 51/473 (10%)
Query: 679 KKGSQ---RWMKLNFEVF-TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPI 734
KKG Q + ++NFE T T + + + A N +G + +
Sbjct: 21100 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP 21159
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
P + P+ ++V+ T W PP G I Y+VE S WV T + R
Sbjct: 21160 GPPTGPIKF--DEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 21216
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV 854
+ L TG FRV N G T A V P P+ T + K
Sbjct: 21217 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQ---VTAVTKD 21273
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF------------VRQA 902
++ P + GG+P+ HV + + + + + +
Sbjct: 21274 SMTISWHEPL----------SDGGSPI--LGYHVERKERNGILWQTVSKALVPGNIFKSS 21321
Query: 903 ARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPK 957
+D YE V ENM + + + ++ PP + + ++W P+
Sbjct: 21322 GLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPE 21381
Query: 958 DDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
G +I Y V+K D W N TVS L Y FRV +N G
Sbjct: 21382 YTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAIS 21441
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
P + IT + + + ++ KF +I + AG + L V G P
Sbjct: 21442 PPSEPSDA-------ITCRD-DVEAPKIKVDVKFKDTVI---LKAGEAFRLEADVSGRPP 21490
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
P + W K+ E+ K I L + + D+G YT A N G A
Sbjct: 21491 PTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 21543
Score = 67.0 bits (162), Expect = 1e-10
Identities = 58/205 (28%), Positives = 84/205 (40%), Gaps = 19/205 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT-SCTVS 994
P ++ VKEV + W PK DG SEI+ Y ++ T ++ V N + TV
Sbjct: 16720 PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVK 16779
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL-TP 1053
L G+ Y +RV NI G K KP K+ +AP L
Sbjct: 16780 GLKEGDTYEYRVSAVNIVGQG-------------KPSFCTKPITCKDE---LAPPTLHLD 16823
Query: 1054 LIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
D++ + G + AL G PKPKV W K++ ++ ED + I L L +
Sbjct: 16824 FRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKR 16883
Query: 1113 FDAGTYTCRAVNELGEALAECKLEV 1137
D+G Y N G C++ V
Sbjct: 16884 SDSGKYCVVVENSTGSRKGFCQVNV 16908
Score = 65.9 bits (159), Expect = 2e-10
Identities = 242/1196 (20%), Positives = 419/1196 (35%), Gaps = 189/1196 (15%)
Query: 41 EDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKS 100
E+Q+ E F+ KP + G V +V G KP + W K G
Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP---KPHVYWKKS-----GVPL 1122
Query: 101 GARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDA 160
+ +K S+N + +L I D G Y + V+ K S ++ EA +
Sbjct: 1123 TTGYRYKVSYNKQTG--ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL 1180
Query: 161 SGQSLESFKRTS-------EKKSDTAGELDFSGLLKKREVVEEE-KKKKKKDDDDLGIPP 212
E +T K +TA +S K+ E + +KK KD +
Sbjct: 1181 MKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYV 1240
Query: 213 EIWEL-LKGAKKSEYEKIAFQYGITDLRGMLKR--LKKAKVEVKKSAAFTKKLDPA---Y 266
E E + ++ ++I ++ T L +L+ +K V++ +S A D Y
Sbjct: 1241 EDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNY 1300
Query: 267 QVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRI-LTINKCTLADDA 324
++ G + ++S L + W+K+G+ IK +Y + + R L I D+
Sbjct: 1301 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360
Query: 325 AYEVAVKDEK----CFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMK 380
Y + K C +L+V EP + P + R+ S + +
Sbjct: 1361 IYTAFASNIKGNAICSGKLYV-EPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSP 1419
Query: 381 DGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE 440
+ R + G+R ++E +E QLE
Sbjct: 1420 ARMSPARMSPARMSPARMSPGRR--------LEE-------------------TDESQLE 1452
Query: 441 VLQDIADLTVKASEQAVFKCEVS-----DEKVTGK------WYKNGVEVRP--SKRITIS 487
L V + FKC D KV G+ W+ +G ++ + ++ I
Sbjct: 1453 RLYK----PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIK 1508
Query: 488 HVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSG 547
G L+I P D G++T V A S + + VE V Q P
Sbjct: 1509 EDGT-QSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---LTVEAVEHQVKPMFVEKLKN 1564
Query: 548 KTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE-GRTRIEKRVDCSSFVIE 606
+ + G++L + V TG P P WLK ++ + + RIE ++ I+
Sbjct: 1565 ------VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1618
Query: 607 SAQREDEGRYTIKVTNPVGEDVASIFLQV-VDVPDP-PEAVRITSVGEDWAILVWEPPMY 664
S +D YT N G D + V V+ +P PE I G A + P +
Sbjct: 1619 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPEL- 1677
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
+P+ + G ++W EG LY+
Sbjct: 1678 ---EPL------HLRYGQEQWE------------------EGDLYDKEKQQKPFFKKKLT 1710
Query: 725 SMNTKPFMP------IAPTSEPLHLI--VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
S+ K F P + P +P ++ + D + R N G +D Y V Y
Sbjct: 1711 SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD-YGVAYS 1769
Query: 777 LE------------GSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
+ G++ E+ LP G + L R+ + E A
Sbjct: 1770 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH-EGAL 1828
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS 884
+E +P + P +R GE G P+P+V W G + S
Sbjct: 1829 TGVTTDQKEKQKPDIVLYPEPVRVL----EGETARFRCRVTGYPQPKVNWYLNGQLIRKS 1884
Query: 885 R--------VH----VRTSDFDTVFFVRQAARSDSG--EYELSVQIENMKDTATIRIRV- 929
+ +H V +DT V+ A + G E+++ ++I+ +D ++ R
Sbjct: 1885 KRFRVRYDGIHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1943
Query: 930 -----------------VEKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V+K P++ V ++ + + P++ + E+ F
Sbjct: 1944 EPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE--SEELRSKF 2001
Query: 969 VQKADKKTMEWFNVYE-RNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
++ ++ E E ++R + +L+ + +T+ + + K A
Sbjct: 2002 KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKEL-----TEEEKKALAEE 2056
Query: 1028 LKTGI-TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
K I TFKP + + APK + + V G A V G P P+ W KN +
Sbjct: 2057 GKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGV 2116
Query: 1087 EI-REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+I R D + V L IR + D+ + +A+N GE + L V+ Q
Sbjct: 2117 KIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 17/203 (8%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
I E+ PP + V + ++A++ W P DG S I GY ++ K + W
Sbjct: 28540 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 28598
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ + TV L+ EY FRV +N G S+ F KE
Sbjct: 28599 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREA-------------FSSVIIKEPQIEP 28645
Query: 1047 APKFLTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104
LT + ++++ AG ++ + G P PKV W +M ++E + IT + T
Sbjct: 28646 TAD-LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTT 28704
Query: 1105 LNIRRPSPFDAGTYTCRAVNELG 1127
L ++ D+G Y N G
Sbjct: 28705 LTVKDSMRGDSGRYFLTLENTAG 28727
Score = 65.5 bits (158), Expect = 3e-10
Identities = 33/94 (35%), Positives = 46/94 (48%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P ++ L + V+ G S L C + G+P P V W + +I F IT G+ L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
R D+G +TC AVNE G C L V+V +
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036
Score = 65.5 bits (158), Expect = 3e-10
Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 18/219 (8%)
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
T + I +++ G P N+ + + T ++W+ P DG S + Y V++ K + +W
Sbjct: 18090 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 18149
Query: 982 VYERNRHTSCTVSDLIVGNEYY-FRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYK 1040
V++ + + + D V N+ Y FRV T+N G SD K ++K + + K
Sbjct: 18150 VHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWV---KTEEVVVKEDLQKPVLDLK 18206
Query: 1041 EHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK--MEIREDPKFLITN 1098
L+ ++ V AG + L VRG P P+V W K+K ++ P+ I
Sbjct: 18207 ----------LSGVL--TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDT 18254
Query: 1099 YQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + D G Y A N G +A + V
Sbjct: 18255 RADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 65.1 bits (157), Expect = 4e-10
Identities = 75/317 (23%), Positives = 124/317 (39%), Gaps = 50/317 (15%)
Query: 269 DRGNKIKLMVEISDPDLTLK--WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G +K + +I + D + + W+ ++++ S KY IL + T DD Y
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 31639
Query: 327 EVAV----KDEKCFTELFVK---------------------------EPPVLIVTPLEDQ 355
V ++ + ELFVK E P PL ++
Sbjct: 31640 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 31699
Query: 356 QVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQE 414
+VG+ V V ++ V W K G ++ D+ K +Y F+ D + L + V +
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFESDKGLYQLTINSVTTD 31758
Query: 415 DRGRYQVITNG----GQCEAELIV------EEKQLEVL--QDIADLTVKASEQAVFKCEV 462
D Y V+ C+A+L V + L + + +A+ + + F+ V
Sbjct: 31759 DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRV 31818
Query: 463 SD-EKVTGKWYKNGVEVRPSKRITISHVG-RFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
S T KW K+G + I I H G ++ L I D PED G Y A S S
Sbjct: 31819 SGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTS 31878
Query: 521 AKLNFLEIKVEYVPKQE 537
+ + ++ Y KQE
Sbjct: 31879 CQAHLQVERLRY-KKQE 31894
Score = 64.7 bits (156), Expect = 5e-10
Identities = 124/619 (20%), Positives = 228/619 (36%), Gaps = 56/619 (9%)
Query: 41 EDQSPTAEEP--TGVFLKKPDSVS-----VETGKDAVVVAKVNGKELPDKPTIKWFKGKW 93
E Q+P T V +K+P S VET K+A V + P + W+K K
Sbjct: 5497 EAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVV-WYKDKR 5555
Query: 94 LELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDV 153
SK + AS + +HI V D G Y + + + D+C + +
Sbjct: 5556 QLRSSKK---------YKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 5606
Query: 154 EAPRQDASGQSLESFKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPE 213
+ P + S L S + + ++ ++ + + + + E+E+ ++ ++ +
Sbjct: 5607 KEPPRFVS--KLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN 5664
Query: 214 IWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNK 273
+ L+ AK + I + GM R A + V + A +K P V G
Sbjct: 5665 V-ATLQFAKAEPANAGKYICQIKNDGGM--RENMATLMVLEPAVIVEKAGP-MTVTVGET 5720
Query: 274 IKLMVEIS-DPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKD 332
L +++ P+L+++W+K+G+ + S K+ F K L I D Y V++
Sbjct: 5721 CTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQN 5780
Query: 333 ----EKCFTELFVKE--PPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVEL 385
C + V + P L++ +G + +V+ V W + ++
Sbjct: 5781 NVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKI 5840
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV----ITNGGQCEAELIVEEKQLEV 441
A+Y+ L + + D G Y + +C A L V+E
Sbjct: 5841 VS----GAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP-SF 5895
Query: 442 LQDIADLTVKASEQAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
+++ L V + F + W++ E+ R I +L + ++
Sbjct: 5896 VKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNI 5955
Query: 501 RPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
G+YT V A S +EP S + E G
Sbjct: 5956 DISQSGEYTCVVSNNAGQASCTTRLF--------VKEPAAFLKRLSDHSVE------PGK 6001
Query: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
+ L+ + TG P TW K TT+E + C ++ S +R D G+Y+ ++
Sbjct: 6002 SIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKR-DAGQYSCEI 6060
Query: 621 TNPVGEDVASIFLQVVDVP 639
N G DV + ++ P
Sbjct: 6061 ENEAGRDVCGALVSTLEPP 6079
Score = 62.0 bits (149), Expect = 3e-09
Identities = 87/412 (21%), Positives = 142/412 (34%), Gaps = 57/412 (13%)
Query: 268 VDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G + IS P + W+K Q + K F + G++ L + + D A Y
Sbjct: 3250 VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVY 3309
Query: 327 EVAVKDE----KCFTELFVKEPPVL------------IVTPLEDQQVFVGDRVEMAVEVS 370
K++ L V+ P V+ I+TPL+D G VS
Sbjct: 3310 TCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVS 3369
Query: 371 EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG---- 426
+V W ++ F R + + L ++ ED G Y + +
Sbjct: 3370 GTDLKVSWYSKDKKIKPSRFF----RMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 3425
Query: 427 -----------------QCEAELIVEEKQLEVLQ-DIADLTVKASEQAVFKCEV-SDEKV 467
+ E E+ +E K V++ I L V A F CE+ S V
Sbjct: 3426 SSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNV 3485
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE 527
+W+K G E+ S + +I L I + D G+YT S+S
Sbjct: 3486 RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT- 3544
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
V + PP + ++ G + ++TG P W K D +
Sbjct: 3545 -----VTEAYPPTF------LSRPKSLTTFVGKAAKFICTVTGTPVIETIWQK-DGAALS 3592
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVP 639
RI + + + +D G Y+ K +N G D+ L ++D P
Sbjct: 3593 PSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644
Score = 61.2 bits (147), Expect = 5e-09
Identities = 96/440 (21%), Positives = 165/440 (37%), Gaps = 55/440 (12%)
Query: 285 LTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELF 340
LT++WFK +E+ + L + +D Y V + +C LF
Sbjct: 4235 LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLF 4294
Query: 341 VKEPPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKK 399
VKEP + Q + GD ++A +V+ ++ W + E+ ++S K R F +
Sbjct: 4295 VKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI--KESSKHRMSFVE 4352
Query: 400 DGKRHILIFSDVVQEDRGRY----QVITNGGQCEAELIVEE--------KQLEVLQDIAD 447
+L +DV ED G Y Q C + +IV+E K +EVL++ D
Sbjct: 4353 --STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEY-D 4409
Query: 448 LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGD 507
+ + A E++ W+K+ +R ++ L I D G+
Sbjct: 4410 VMLLAEVAGTPPFEIT-------WFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGE 4462
Query: 508 YTF-VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y V + S+ + V +EPP +S + G
Sbjct: 4463 YQCRVTNEVGSSICS---------ARVTLREPPSFIKKIESTSS------LRGGTAAFQA 4507
Query: 567 SITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 625
++ G P TWLK DE+ T + R+ + +S + + + +G+Y + N G
Sbjct: 4508 TLKGSLPITVTWLKDSDEI--TEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAG 4565
Query: 626 EDVASIFLQVVD-VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQR 684
S L V + EAV I D A L + G K +T + K G +
Sbjct: 4566 IQRCSALLSVKEPATITEEAVSIDVTQGDPATL---QVKFSGTKEIT---AKWFKDGQEL 4619
Query: 685 WMKLNFEVFTETTYESTKMI 704
+ +++ T K+I
Sbjct: 4620 TLGSKYKISVTDTVSILKII 4639
Score = 60.5 bits (145), Expect = 9e-09
Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 19/196 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYE-RNRHTSCTVS 994
P + V +V + + W+ P DG S + GY ++ T W V + TV+
Sbjct: 29638 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 29697
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTP 1053
L G +Y FR+ +N G+S+ R T +T + D R+ P L+
Sbjct: 29698 SLNEGEQYLFRIRAQNEKGVSEP--------RETVTAVTVQ-------DLRVLPTIDLST 29742
Query: 1054 LIDRV--VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
+ + V AG L + G P P W ++RE + + + V L IR +
Sbjct: 29743 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETT 29802
Query: 1112 PFDAGTYTCRAVNELG 1127
D G YT N G
Sbjct: 29803 IRDTGEYTLELKNVTG 29818
Score = 59.7 bits (143), Expect = 2e-08
Identities = 69/295 (23%), Positives = 117/295 (39%), Gaps = 27/295 (9%)
Query: 348 IVTPLEDQQVFVGDRVEMAVEV-SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
I + +V G + V S+ A+V W +GVEL ++S K Y G +
Sbjct: 32376 ITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESSKIHYT-NTSGVLTLE 32432
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
I D +D G Y+ + + EA D A L V + + + DE+
Sbjct: 32433 IL-DCHTDDSGTYRAVCTNYKGEAS------------DYATLDVTGGDYTTYASQRRDEE 32479
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDG---YALSLSAKL 523
V + E+ ++ +S + ++ E + T + Y S SA++
Sbjct: 32480 VPRSVFP---ELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEM 32536
Query: 524 NFLEIKVEYVP-KQEPPKIHLDCSGK--TSENAIVVVAGNKLRLDVSITGEPPPVATWLK 580
++ + + K KI + + T ++ V G R GEP P TWL+
Sbjct: 32537 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 32596
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
+V +T+ R ++ S+F I S Q DEG Y++ V N G+ A L +
Sbjct: 32597 KGQVLSTS-ARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 32650
Score = 59.3 bits (142), Expect = 2e-08
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 31/222 (13%)
Query: 439 LEVLQDIADLTVKASE----QAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHK 494
L+ +++I D+ + SE A+F+C VS W K+G +R S + G+ K
Sbjct: 11115 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174
Query: 495 LVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAI 554
L I DV+ D G+YT V L K + ++ VE +P + KT E +
Sbjct: 11175 LHIIDVQLSDAGEYTCV---LRLGNKEKTSTAKLVVEELPVR---------FVKTLEEEV 11222
Query: 555 VVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 614
VV G L L + E V W K ++ GR + I A D G
Sbjct: 11223 TVVKGQPLYLSCELNKERDVV--WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAG 11280
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
YT+ V N + +S V++ V DW +
Sbjct: 11281 TYTVTVENANNLECSS-------------CVKVVEVIRDWLV 11309
Score = 59.3 bits (142), Expect = 2e-08
Identities = 118/608 (19%), Positives = 216/608 (35%), Gaps = 90/608 (14%)
Query: 6 PAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPT------GVFLKKPD 59
P K+P+ P+ EA ++P+ + P+ SPT +PT + + P
Sbjct: 32663 PPRVKSPE----PRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPP 32718
Query: 60 SVS----VETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGARFSFKESHNSAS 114
++ E K+ + V + + W+K GK L K F F H SA
Sbjct: 32719 KITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL----KENGHFQF---HYSAD 32771
Query: 115 NVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEA-----PRQDASGQSLESFK 169
Y EL I + D+G Y E+ + +A + ++ +S +
Sbjct: 32772 GTY--ELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQ 32829
Query: 170 RTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLG----------IPPEIWELLK 219
+T+E E + + V+ + D + P IW
Sbjct: 32830 KTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIW---- 32885
Query: 220 GAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKL-DPAYQVDRGNKIKLMV 278
K + +Y +++ +G L+ K + S +T + + A V K+ +
Sbjct: 32886 -TKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 32943
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
I D + + EI P K V + ++ L + +++ + E E+
Sbjct: 32944 -IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 33002
Query: 339 LFVKEPPVLIVTPLE---------------------------DQQVFVGDRVEMAVEVSE 371
L +E T LE Q+ + + + ++ +
Sbjct: 33003 LISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANI 33062
Query: 372 EGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI--TNGG-- 426
GA V W+ +GVELT + YR+ G L D G I T G
Sbjct: 33063 AGATDVKWVLNGVELTNSE----EYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIV 33118
Query: 427 QCEAELIVEEKQLEV---LQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSK 482
+C+ +L + ++ + + + + +F CE+S E +W+KN + + S
Sbjct: 33119 KCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISS 33178
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
++IS + L I + D G YT + SA + + + + P +E +
Sbjct: 33179 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSRE---VV 33235
Query: 543 LDCSGKTS 550
L SG TS
Sbjct: 33236 LRTSGDTS 33243
Score = 56.6 bits (135), Expect = 1e-07
Identities = 26/79 (32%), Positives = 41/79 (51%)
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
G L C + G P +VVW+K++ ++R KF IT+ +L+I D G Y C+
Sbjct: 6472 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 6531
Query: 1122 AVNELGEALAECKLEVRVP 1140
A NE+G C ++ + P
Sbjct: 6532 ATNEVGSDTCSCSVKFKEP 6550
Score = 56.6 bits (135), Expect = 1e-07
Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 605 IESAQREDEGRYTIKVTNPVGEDVAS------IFLQVVDVPDPPEAVRITSVGEDWAILV 658
+++ + E ++ +K N +G S + ++ P PP R+ + L
Sbjct: 18457 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 18516
Query: 659 WEPPMYDGGKPVTGYLVERKKK-----GSQRWMKLNFEV-FTETTYESTKMIEGILYEMR 712
W P+YDGG P+ GY+VE + K + W + N + T + E YE R
Sbjct: 18517 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 18576
Query: 713 VFAVNAIGVSQPS 725
V A N +G+ +P+
Sbjct: 18577 VCAQNQVGIGRPA 18589
Score = 56.2 bits (134), Expect = 2e-07
Identities = 50/208 (24%), Positives = 85/208 (40%), Gaps = 25/208 (12%)
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ-KADKKTMEWFNVYERNRHTSCTV 993
PP + V E+ +A + W P DG ++I GY + +++ + + Y + S V
Sbjct: 18801 PPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVV 18860
Query: 994 SDLIVGNEYYFRVYTENICGLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF 1050
+ L G +Y FRV N G+S ++ GV Y+ + + PK
Sbjct: 18861 TGLKEGKKYKFRVAARNAVGVSLPREAEGV------------------YEAKEQLLPPKI 18902
Query: 1051 LTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
L P +++ + AG + V G P P W K + E+ + L I+
Sbjct: 18903 LMP--EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 18960
Query: 1110 PSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D+G Y+ A N G + K+ V
Sbjct: 18961 VTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 55.1 bits (131), Expect = 4e-07
Identities = 59/225 (26%), Positives = 87/225 (38%), Gaps = 30/225 (13%)
Query: 927 IRVVEKAGPPIN---VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
I V+ GPP + + E + ++W+ P+ +G S I GY ++K ++ V
Sbjct: 15286 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 15345
Query: 984 ERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+R TS V +L Y FRV N G S+ P + P
Sbjct: 15346 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE-PSL---------------PLNVVIQ 15389
Query: 1043 DFRMAPKFLTPLIDR----VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL--- 1095
D + P L R V AG + V G P PK+ W KN+ I + L
Sbjct: 15390 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 15449
Query: 1096 ---ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + L+I + D GTYT A N LG +EV
Sbjct: 15450 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 15494
Score = 55.1 bits (131), Expect = 4e-07
Identities = 72/327 (22%), Positives = 125/327 (38%), Gaps = 24/327 (7%)
Query: 518 SLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVAT 577
+L + + EI PK + P I + N V N L +TG P P+
Sbjct: 30903 NLGGESEWSEISEPITPKSDVP-IQAPHFKEELRNLNVRYQSNAT-LVCKVTGHPKPIVK 30960
Query: 578 WLKGDEVFTTTEGRTRIEK-RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV- 635
W + + + RI++ + +I S +D Y ++ TN G + L+V
Sbjct: 30961 WYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Query: 636 ----VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE 691
+ +P E + + + P GKP ++ +K +++
Sbjct: 31021 VPAKIHLPKTLEGMGAVHALRGEVVSIKIP---FSGKPDP--VITWQKGQDLIDNNGHYQ 31075
Query: 692 VFTETTYESTKMIEGILYEMRVFAV----NAIGVSQPSMNTKPFMPIAPTSEPLHLI-VE 746
V ++ S G+ + F V N G+ Q ++ + +A +P + V
Sbjct: 31076 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE----LDVADVPDPPRGVKVS 31131
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
DV+ + L W P G I Y+VE C +E W+ R +TV NL
Sbjct: 31132 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR--YTVINLFGKTS 31189
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIRE 833
FRV+ N G S+P+ ++P +E
Sbjct: 31190 YQFRVIAENKFGLSKPSEPSEPTITKE 31216
Score = 53.5 bits (127), Expect = 1e-06
Identities = 65/294 (22%), Positives = 116/294 (39%), Gaps = 32/294 (10%)
Query: 854 VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYEL 912
VGE + G +V W K + + + + + V + + DSG+Y
Sbjct: 8166 VGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTC 8225
Query: 913 SVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKA 972
E KD+ T ++ + E+ PP T L E + +GNS + V +
Sbjct: 8226 YAVNEVGKDSCTAQLNIKERLIPPSF--------TKRLSE-TVEETEGNSFKLEGRVAGS 8276
Query: 973 DKKTMEWF-NVYERNRHTSCTVSDLIVGNEYYFRVYTENI-------CGLSDSPGVSKNT 1024
T+ W+ N E ++C ++ N +V + C +S+ G + T
Sbjct: 8277 QPITVAWYKNNIEIQPTSNCEIT--FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCT 8334
Query: 1025 ARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKN 1084
+ I+ KP + +H LTP+ V G L+C V+G ++ W+K
Sbjct: 8335 SSIVIKEPK-KPPVFDQH--------LTPV---TVSEGEYVQLSCHVQGSEPIRIQWLKA 8382
Query: 1085 KMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
EI+ + + G L +R + D+G Y C+A N G + K+ ++
Sbjct: 8383 GREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/93 (34%), Positives = 40/93 (43%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P F+ L D + G S L C V G V W ++ EI PK + + V TLN+
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 6800
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
P D G YTC A N G L V+ P
Sbjct: 6801 SLLEPSDTGIYTCVAANVAGSDECSAVLTVQEP 6833
Score = 52.0 bits (123), Expect = 3e-06
Identities = 70/293 (23%), Positives = 112/293 (38%), Gaps = 38/293 (12%)
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD-FDTVFFVRQAARSDSGEYELS 913
G + L G P +VVW K + S+ TS FDT + SD GEY
Sbjct: 6472 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 6531
Query: 914 VQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKAD 973
E DT + ++ E PP VK++ T+ L+ G++ + V+
Sbjct: 6532 ATNEVGSDTCSCSVKFKE---PPR--FVKKLSDTSTLI--------GDAVELRAIVEGFQ 6578
Query: 974 KKTMEWFN----VYERNRHTSCTVSDLIVGNEYYFRVYTEN---ICGLSDSPGVSKNTAR 1026
++ W V + +T + D I + + + IC + + G+ + +A
Sbjct: 6579 PISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAV 6638
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
+ +P E P+ +T V G AL C V G P+ W K+
Sbjct: 6639 LT----VLEPARIIEK-----PEPMT------VTTGNPFALECVVTGTPELSAKWFKDGR 6683
Query: 1087 EIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
E+ D K IT V +L I D G Y+ N +G+ + C + V V
Sbjct: 6684 ELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGK--SNCTVSVHV 6734
Score = 51.2 bits (121), Expect = 5e-06
Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P +TPL D V G A C V G KV W +I+ F +T ++ L I
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P D GTYT A N +G+ + L + P+
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3437
Score = 51.2 bits (121), Expect = 5e-06
Identities = 68/310 (21%), Positives = 115/310 (37%), Gaps = 56/310 (18%)
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ--VITN 424
+E ++ QV W +L + ++ Y +DG IL D+ + D G Y+ V+ +
Sbjct: 31591 IENYDQSTQVTWYFGVRQLENSEKYEITY---EDGVA-ILYVKDITKLDDGTYRCKVVND 31646
Query: 425 GGQCE--AELIVE---------------------------EKQLEVLQDIADLTVKASEQ 455
G+ AEL V+ E+ E + + T E
Sbjct: 31647 YGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN 31706
Query: 456 AVFKCEVS---DEKVTGKWYKNGVEVRPS---KRITISHVGRFHKLVIDDVRPEDEGDYT 509
F ++ + VT WYK+G +++P K+ T ++L I+ V +D+ +YT
Sbjct: 31707 VRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 31764
Query: 510 FVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA----GNKLRLD 565
V S K V PP D + + ++ A G + +
Sbjct: 31765 VVARNKYGEDSCKAKLT------VTLHPPPT---DSTLRPMFKRLLANAECQEGQSVCFE 31815
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 625
+ ++G PPP W K + + I + +D + I ED G Y + TN G
Sbjct: 31816 IRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 31875
Query: 626 EDVASIFLQV 635
LQV
Sbjct: 31876 STSCQAHLQV 31885
Score = 50.8 bits (120), Expect = 7e-06
Identities = 58/281 (20%), Positives = 104/281 (37%), Gaps = 30/281 (10%)
Query: 866 GKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF-VRQAARSDSGEYELSVQIENMKDTAT 924
G P +V W K G + SR + + + F ++ + DSG+Y V+ + +
Sbjct: 5166 GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCD 5225
Query: 925 IRIRVVEKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEIMG-YFVQKADKKTMEW 979
+RV+++ PP + +V G++ +E K G+ I +F + T
Sbjct: 5226 AYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMEC---KVSGSLPISAQWFKDGKEISTSAK 5282
Query: 980 FNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEY 1039
+ + R S V++L + + + N+ G G+ +T K
Sbjct: 5283 YRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGI-----------LTVKE--- 5328
Query: 1040 KEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNY 1099
P FL + + + ++G P K+ W K+ +E+ PK I
Sbjct: 5329 -------PPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLE 5381
Query: 1100 QGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
LN+ G YTC N++G L V P
Sbjct: 5382 GSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP 5422
Score = 49.3 bits (116), Expect = 2e-05
Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 17/204 (8%)
Query: 443 QDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKR--ITISHVGRFHKLVIDD 499
Q + + V A F+ +S V W+++G + S + IS KL I
Sbjct: 10 QPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPA 69
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V + G Y+ + ++ L +K E P ++ ++ V G
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELL-VKAETAPPNFVQRLQ----------SMTVRQG 118
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+++RL V +TG P PV + + G E+ ++ + +I + D S +I A ED G Y++
Sbjct: 119 SQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 619 KVTNPVGEDVASIFLQVVDVPDPP 642
TN VG ++ L V + P
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVP 200
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Query: 351 PLEDQQVFVGDRVEMAVEVSEEGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFS 409
PL+ V G +S +V W +DG ++ + F DG+ + I +
Sbjct: 11 PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRAKLTIPA 69
Query: 410 DVVQEDRGRYQV-ITNG-GQCE--AELIVEEKQL--EVLQDIADLTVKASEQAVFKCEVS 463
V + + GRY + TNG GQ AEL+V+ + +Q + +TV+ Q + V+
Sbjct: 70 -VTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 464 DEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
K+Y++G E++ S IS G + L+I + PED G Y+
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/94 (30%), Positives = 40/94 (42%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P+ L L V +G A + G P+PK+ W K + + K + TL +
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P DA YTC A N+ G A L V VP+
Sbjct: 3299 IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR---EDPKFLITNYQGVLT 1104
P+F PL ++ G + + HP+P V W K+ +I+ D K+ + +G+
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L I + D YT A N+ GE + KL V
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 48.5 bits (114), Expect = 4e-05
Identities = 76/332 (22%), Positives = 117/332 (35%), Gaps = 51/332 (15%)
Query: 243 KRLKKAKVEVKKSAAFTKKLDP-------AYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQ 294
++ + K EV FT P +++V G + ++ + S P +KW+ NG
Sbjct: 32353 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 32412
Query: 295 EIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLED 354
E++ SSK + N L I C D Y + K + L VT
Sbjct: 32413 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYA----TLDVTG--- 32465
Query: 355 QQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGK-------RHILI 407
GD A + +E ELTR +++ A FKK + R +
Sbjct: 32466 -----GDYTTYASQRRDEEVPRSVFP---ELTRTEAY-AVSSFKKTSEMEASSSVREVKS 32516
Query: 408 FSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE---------------VLQDIADLTVKA 452
+E Y+ + A L EEK LE +L +TV
Sbjct: 32517 QMTETRESLSSYEHSASAEMKSAAL--EEKSLEEKSTTRKIKTTLAARILTKPRSMTVYE 32574
Query: 453 SEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
E A F C+ E V T W + G + S R ++ I V+ DEG+Y+ V
Sbjct: 32575 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVV 32634
Query: 512 PDGYALSLSAKLNFLEIKVEYVPK--QEPPKI 541
+ A+ K K PP++
Sbjct: 32635 VENSEGKQEAEFTLTIQKARVTEKAVTSPPRV 32666
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/91 (32%), Positives = 40/91 (43%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
AP+ + V G + V+ P +V W N +E++E K TN GVLTL
Sbjct: 32373 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 32432
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
I D+GTY N GEA L+V
Sbjct: 32433 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1032 ITFKPFEYKEHDFRMAP--KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR 1089
+T K F+ + F P +F PL D+ V G +A L C V KV W KN EI
Sbjct: 12267 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEIL 12325
Query: 1090 EDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
+ K+ I V L I +P D TYTC A
Sbjct: 12326 KSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 12358
Score = 44.7 bits (104), Expect = 5e-04
Identities = 48/210 (22%), Positives = 76/210 (36%), Gaps = 28/210 (13%)
Query: 457 VFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGY 515
V K E D+ WY ++ S++ I++ L + D+ D+G Y V + Y
Sbjct: 31588 VCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDY 31647
Query: 516 ALSLSAKLNFL----EIKVEYVPK---------------QEPPKIHLDCSGKTSENAIVV 556
S F+ E+ Y + + PP+ L KT+
Sbjct: 31648 GEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA------ 31701
Query: 557 VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSF--VIESAQREDEG 614
G +R V+IT P P TW K + + + D + I S +D+
Sbjct: 31702 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 31761
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEA 644
YT+ N GED L V P P ++
Sbjct: 31762 EYTVVARNKYGEDSCKAKLTVTLHPPPTDS 31791
Score = 44.3 bits (103), Expect = 7e-04
Identities = 28/91 (30%), Positives = 42/91 (46%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P F+ L V G L V G P P V + ++ EI+ F I+ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
P D+GTY+ A N +G A + +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED--PKFLITNYQGVLT 1104
AP F PL VV+ G +A + G P P+V W ++ I P I+ G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L I + ++G Y+ +A N G+A + +L V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/170 (22%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
++VV+ G+ + I+G P P +W + G + T+T +I + I + +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
+ GRY++K TN G+ ++ L V PP V+ ++ V + VT
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-----SMTVRQGSQVRLQVRVT 128
Query: 672 GY---LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
G +V+ + G++ L+F++ E S + E + ++VNA
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNA 178
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/285 (21%), Positives = 104/285 (36%), Gaps = 41/285 (14%)
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDR-----GRYQVITNGGQCEAELIVEEKQLEVLQ 443
D++K+ + + + I V+E+R GR +T + A + + ++
Sbjct: 888 DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVS 947
Query: 444 DIADLTVKASEQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRP 502
+ ++TV E +C +S T WY+ ++ S I+ +L+I +
Sbjct: 948 GLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFA 1007
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKV-EYVPKQ----------------EPPKIHLDC 545
ED G +T A ++S +L ++V E K+ E + +
Sbjct: 1008 EDSGRFTCSAVNEAGTVSTSC-YLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1066
Query: 546 SGKTSENA--------------IV--VVAGNKLRLDVSITGEPPPVATWLKGDEVFTT-T 588
+ T E A +V +V G + + G P P W K TT
Sbjct: 1067 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGY 1126
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
+ K+ VI +D G YTI V N GE AS L
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 40.4 bits (93), Expect = 0.010
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
+ V+ G + L+ I+G P P TW + D ++ ++ + + + + + +I A ED
Sbjct: 952 VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLMIREAFAED 1009
Query: 613 EGRYTIKVTNPVGEDVASIFLQV 635
GR+T N G S +L V
Sbjct: 1010 SGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 39.3 bits (90), Expect = 0.022
Identities = 61/266 (22%), Positives = 111/266 (41%), Gaps = 32/266 (12%)
Query: 2 PEAKPAAKKAPKGKDAPK--GAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPD 59
P+ KKA K KDA K PKE P+E E K+ PP PT P K P+
Sbjct: 8979 PKRIEVTKKAVK-KDAKKVVAKPKEMTPRE---EIVKKPPP----PTTLIPA----KAPE 9026
Query: 60 SVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSAS-NVYT 118
+ V + + V + + K+ K ++ K K SF+E ++ YT
Sbjct: 9027 IIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYT 9086
Query: 119 VELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKSDT 178
D Y ++V+AK +V ++ + E ++R ++
Sbjct: 9087 EPFEQPYYEEPDEDYEEIKVEAKK---------EVHEEWEEDFEEGQEYYER---EEGYD 9134
Query: 179 AGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDL 238
GE ++ ++REV++ +K+ + + + +P ++ E K K+ + I +
Sbjct: 9135 EGEEEWEEAYQEREVIQVQKEVYE-ESHERKVPAKVPE----KKAPPPPKVIKKPVIEKI 9189
Query: 239 RGMLKRLKKAKVEVKKSAAFTKKLDP 264
+R+++ KV+V K +KK+ P
Sbjct: 9190 EKTSRRMEEEKVQVTKVPEVSKKIVP 9215
Score = 38.9 bits (89), Expect = 0.028
Identities = 19/61 (31%), Positives = 31/61 (50%)
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+V W ++ K+ IT GV L ++ + D GTY C+ VN+ GE + +L V
Sbjct: 31599 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Query: 1138 R 1138
+
Sbjct: 31659 K 31659
Score = 38.1 bits (87), Expect = 0.048
Identities = 48/197 (24%), Positives = 83/197 (42%), Gaps = 29/197 (14%)
Query: 287 LKWFKNGQEIK----PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEK----CFTE 338
+ WF++GQ I P + F + K LTI T A+ Y + + E
Sbjct: 37 VSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTAE 94
Query: 339 LFVKEP--PVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM-WMKDGVELTREDSFKARY 395
L VK P V L+ V G +V + V V+ V+ + +DG E+ F+
Sbjct: 95 LLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQ--- 151
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQV-ITNG---GQCEAELIVEEKQLEVLQDIADLTVK 451
++G + L+ ++ ED G Y V TN AEL+V+ ++ ++ K
Sbjct: 152 -ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--------EVPAK 202
Query: 452 ASEQAVFKCEVSDEKVT 468
++ V ++S+ + T
Sbjct: 203 KTKTIVSTAQISESRQT 219
Score = 37.7 bits (86), Expect = 0.063
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 14/105 (13%)
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
T+R + PP+ LP + + Y VGE + V P P V W K G ++
Sbjct: 31682 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIK 31731
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG 934
D D + SD G Y+L++ D A + K G
Sbjct: 31732 PGDNDK----KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 31772
Score = 37.4 bits (85), Expect = 0.082
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 21/97 (21%)
Query: 237 DLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQE 295
DLRG+ ++L AK G+ IK+ + + P T+ W K Q
Sbjct: 21066 DLRGIYQKLVIAKA--------------------GDNIKVEIPVLGRPKPTVTWKKGDQI 21105
Query: 296 IKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKD 332
+K + + FE IL IN+C +D Y + ++
Sbjct: 21106 LKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 21142
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 22/93 (23%)
Query: 1006 VYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSA 1065
VYT + G K +AR+ TGI K F++PL D+ V G +A
Sbjct: 11553 VYTAEVEG-------KKTSARLFVTGIRLK--------------FMSPLEDQTVKEGETA 11591
Query: 1066 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITN 1098
C + H K VVW KN ++ LI++
Sbjct: 11592 TFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISS 11623
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 1/82 (1%)
Query: 252 VKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKK 310
V S KL V G ++ I P T KW +G EIK Y E
Sbjct: 17506 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 17565
Query: 311 RILTINKCTLADDAAYEVAVKD 332
+LTI C D Y++ V +
Sbjct: 17566 SVLTIKNCLRRDTGEYQITVSN 17587
Score = 36.2 bits (82), Expect = 0.18
Identities = 57/267 (21%), Positives = 99/267 (37%), Gaps = 40/267 (14%)
Query: 874 WTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W + G L T+ + + + D GEY + ++ K +A +++ V+
Sbjct: 2652 WLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVKI 2709
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT 992
N+ V E VE P G I V ++++K + + + S
Sbjct: 2710 KKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEK----YAISVKGTIYSLR 2765
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
+ + + +E VY + L S + T +I+K PK +T
Sbjct: 2766 IKNCAIVDE---SVYGFRLGRLGASARLHVETVKIIKK-----------------PKDVT 2805
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
L + V S + H V W +EI+ K + + + V L ++ SP
Sbjct: 2806 ALENATVAFEVSVS-------HDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2858
Query: 1113 FDAGTYTCRAVNELGEALAECKLEVRV 1139
DAG YT V +L ECK ++ V
Sbjct: 2859 SDAGEYTA-VVGQL-----ECKAKLFV 2879
Score = 36.2 bits (82), Expect = 0.18
Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P F L + G S V G P P + W K+ + P I ++G+
Sbjct: 31790 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 31848
Query: 1103 --LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+IR P D G Y A N G + L+V
Sbjct: 31849 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 35.8 bits (81), Expect = 0.24
Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 6/85 (7%)
Query: 1 MPEAKPAAKKAPKGK-DAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPD 59
+PE P + P+ K P EAPP + P EAPKE PE + P P + P
Sbjct: 10495 VPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVP-EAPKEVVPEKKVPV---PPPKKPEVPP 10550
Query: 60 SVSVETGKDAVVVAKVNGKELPDKP 84
+ E K AV KV + +P KP
Sbjct: 10551 TKVPEVPKAAVPEKKV-PEAIPPKP 10574
Score = 35.0 bits (79), Expect = 0.41
Identities = 32/88 (36%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Query: 1 MPEAKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPD- 59
+PE AA K +A P E+PP E P EAPKE PE + P A KKP+
Sbjct: 10553 VPEVPKAAVPEKKVPEAIPPKP-ESPPPEVP-EAPKEVVPEKKVPAAPP------KKPEV 10604
Query: 60 -SVSVETGKDAVVVAKVNGKELPDKPTI 86
V V VV K P KP +
Sbjct: 10605 TPVKVPEAPKEVVPEKKVPVPPPKKPEV 10632
Score = 34.3 bits (77), Expect = 0.69
Identities = 29/73 (39%), Positives = 34/73 (46%), Gaps = 13/73 (17%)
Query: 3 EAKPAA-----KKAPKGKDAPKGAPK--EAPPKEAPAEAPKEAPPEDQSPT-----AEEP 50
EA PA KK K P APK EAPP + P E PK+ PE++ PT E P
Sbjct: 10026 EAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP-EVPKKLIPEEKKPTPVPKKVEAP 10084
Query: 51 TGVFLKKPDSVSV 63
KK + V V
Sbjct: 10085 PPKVPKKREPVPV 10097
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDTVFFVRQAAR 904
Q+ + G G P P+V W + G + TS V + SD + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
++SG Y L + + T+T + V + PP
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 32.7 bits (73), Expect = 2.0
Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 21/88 (23%)
Query: 2 PEAKP-----AAKKAPKGKDAPKGAPK--EAPPKEAPAEAPKEAPPEDQSPTA------- 47
PE P A K+ K P PK E PP + P E PK A PE + P A
Sbjct: 10602 PEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP-EVPKVAVPEKKVPEAIPPKPES 10660
Query: 48 ------EEPTGVFLKKPDSVSVETGKDA 69
EEP V L++P + VE + A
Sbjct: 10661 PPPEVFEEPEEVALEEPPAEVVEEPEPA 10688
Score = 32.7 bits (73), Expect = 2.0
Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 16/95 (16%)
Query: 2 PEAKPAAKKAPKGKDAPKGAPK------EAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFL 55
P A P PK K AP E PP + P E PKE PE + P V
Sbjct: 10687 PAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVP-EVPKEVVPEKKVPL------VVP 10739
Query: 56 KKPDSVSV---ETGKDAVVVAKVNGKELPDKPTIK 87
KKP++ E K+ V KV + P+ P K
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAK 10774
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 268 VDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G ++L++ I+ P WF G +++ S + E K LTI + T+ D Y
Sbjct: 29750 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEY 29809
Query: 327 EVAVKD 332
+ +K+
Sbjct: 29810 TLELKN 29815
Score = 32.3 bits (72), Expect = 2.6
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 873 VWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
VW K G + S RVH+ + + + D+G Y ++ + + + + V+
Sbjct: 2387 VWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2446
Query: 932 KAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
P +V V E GT A++E + D S
Sbjct: 2447 VITPLKDVNVIE--GTKAVLECKVSVPDVTS 2475
Score = 32.0 bits (71), Expect = 3.4
Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 268 VDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K+ + V + P T+ W K+G+E+K S + +N L + K AD Y
Sbjct: 14398 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 14457
Query: 327 EVAVKDE 333
+ ++++
Sbjct: 14458 TITLENK 14464
Score = 31.6 bits (70), Expect = 4.5
Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 6/122 (4%)
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK-----FLTPLIDRVVVAGY 1063
+N+C L ++++A I+ I E H F + F L D V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAG-ETSSHAFLLVQAKQLITFTQELQDVVAKEKD 2189
Query: 1064 SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAV 1123
+ A P KV W K+ ME+ E K+ + + + V L+I DA Y+C V
Sbjct: 2190 TMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 1124 NE 1125
+
Sbjct: 2250 ED 2251
Score = 31.6 bits (70), Expect = 4.5
Identities = 29/104 (27%), Positives = 40/104 (38%), Gaps = 12/104 (11%)
Query: 1048 PKFLTPLIDRVVVAGY-SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P T I +VV+ + SA C V V W K E+ E K+ N +
Sbjct: 8833 PIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMT 8891
Query: 1107 IRRPSPFDAGTYT----------CRAVNELGEALAECKLEVRVP 1140
I +P D G Y+ R+ EL E KLE++ P
Sbjct: 8892 IHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPP 8935
Score = 31.6 bits (70), Expect = 4.5
Identities = 60/257 (23%), Positives = 100/257 (38%), Gaps = 50/257 (19%)
Query: 45 PTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGAR 103
PT +F + + + G+ +V+G +P PT+KW K G+ L LG
Sbjct: 31788 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG--IPP-PTLKWEKDGQPLSLGPNI--- 31841
Query: 104 FSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPR-QDASG 162
E + + Y LHI + D GYYR+ SC ++ VE R +
Sbjct: 31842 ----EIIHEGLDYYA--LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEF 31895
Query: 163 QSLESFKRTSEKKSDTAGELDFSGLLKKREVV--EEEKKKKKKDDDDLGIPPEIWELLKG 220
+S E +R +K+ D L + +L E V + K+ ++ L P + +KG
Sbjct: 31896 KSKEEHERHVQKQIDKT--LRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKG 31953
Query: 221 ------AKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKI 274
+K E K+ Y + + R + K+ +E +I
Sbjct: 31954 EFRLEIEEKKEERKLRMPYDVPEPR----KYKQTTIE------------------EDQRI 31991
Query: 275 KLMVEISDPDLTLKWFK 291
K V +SD +KW+K
Sbjct: 31992 KQFVPMSD----MKWYK 32004
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 261 KLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCT 319
KL V G KI+L ++ P+ + W K +K + ENV KK +TI
Sbjct: 13695 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSK 13754
Query: 320 LADDAAY 326
+D Y
Sbjct: 13755 RSDTGTY 13761
Score = 30.8 bits (68), Expect = 7.7
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+FL PL D V A C + KV W K+ EI++ K+ I + V L I
Sbjct: 12375 EFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVIN 12433
Query: 1109 RPSPFDAGTYTC 1120
+ D Y+C
Sbjct: 12434 KCLLDDEAEYSC 12445
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 275 bits (704), Expect = 1e-73
Identities = 222/790 (28%), Positives = 337/790 (42%), Gaps = 43/790 (5%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
++S +KW++NG+EIK KY FE G L I C L D+ Y V+D K
Sbjct: 6540 QLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRAR 6599
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
LFV+E PV I+ P +D G V E++++ +V W+++ + + + D +++
Sbjct: 6600 LFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD----KHQMM 6655
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEA--ELIVEEKQLEVLQDIA-----DLTVK 451
+GK H L D+ D+G Y+ I + A EL K QD+ LT+
Sbjct: 6656 SEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMV 6715
Query: 452 ASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
A K E +W+K E P TI I + + D+G Y V
Sbjct: 6716 VPYDAYPKAEA-------EWFK---ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIV 6765
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
+N I V + D + + G+K+ + +
Sbjct: 6766 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKI-IGYVVERR 6824
Query: 572 PPPVATWLKGDEVFTTTEGR-TRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS 630
TW+ + + E T ++K F + + R G ++ NPV + S
Sbjct: 6825 DIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE-PVETDNPV--EARS 6881
Query: 631 IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRW---MK 687
+ DVP PP V IT V L WEPP YDGG +T Y++E + K S RW M
Sbjct: 6882 KY----DVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 6937
Query: 688 LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHL 743
+ E + T T ++EG Y RV A N IGV +PS T PF+ PI S P++L
Sbjct: 6938 VRAEDLSATV---TDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNL 6993
Query: 744 IVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPT 803
D T ++ LKW PP + G I GY++E C EG + W+ N + V + V L
Sbjct: 6994 TSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK 7053
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP 863
G + L+RV N AG S+P+ + P+T + P + L + V + ++VP
Sbjct: 7054 GNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVI-VPNPITILVP 7112
Query: 864 FQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
G PRP W G L+T RV ++T + + RSD G Y L ++ +
Sbjct: 7113 STGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7172
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I + V+ + P + ++ + + W+ P DDG S + GY V+K + W V
Sbjct: 7173 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 7232
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+ TV DL+ G EY F+V N CG + V + + P K
Sbjct: 7233 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWR 7292
Query: 1043 DFRMAPKFLT 1052
D FLT
Sbjct: 7293 DRTANSIFLT 7302
Score = 274 bits (701), Expect = 3e-73
Identities = 167/480 (34%), Positives = 243/480 (50%), Gaps = 13/480 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP+I LD + +V+ A LRL V+I G P P W K + + T R +IE
Sbjct: 18798 EPPEIELDADLR---KVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTD---RAQIEV 18851
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ VI++ R D GRY + + N G A + ++V+D P P + I V +D
Sbjct: 18852 TSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVT 18911
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L WEPP+ DGG +T Y+VE+++ + + + T+TT+ + EG Y RV A
Sbjct: 18912 LSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC-TKTTFRIENLQEGCSYYFRVLAS 18970
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G+ P+ T+P P P + + DVT T T+KW P G I GY+VE
Sbjct: 18971 NEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 19030
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
+GSE+W + V+ T+ L G +FRV VN GRS+P L PV R+I
Sbjct: 19031 TKGSEKW--STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEI 19088
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDT 895
P + LP H T+ K EQL + VPF+G+P+ V W K G L +T+RV+V +S T
Sbjct: 19089 KPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT 19145
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++A++ D G YEL V T I I V+++ GPP + + EV + + W
Sbjct: 19146 SLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 19205
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG +I Y V+K + + W V + TS + L G+EY FRV EN G S
Sbjct: 19206 PEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19265
Score = 265 bits (678), Expect = 1e-70
Identities = 169/568 (29%), Positives = 272/568 (47%), Gaps = 23/568 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P++ LD + IVV AG R+ + G P P TW + + FT + +I
Sbjct: 17713 KLEAPELDLDSELR---KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD---KVQI 17766
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
EK V+ + I++ R D G+Y +K+ N G A + ++V+D P PP+ + + V +D
Sbjct: 17767 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDS 17826
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A LVWEPP+ DGG V Y++++++ + + ++ + ++T+++ + EG +Y RV
Sbjct: 17827 AFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKC-SKTSFKVENLTEGAIYYFRVM 17885
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N GV P P S P + + DV+ T+ +L W P G + GY+VE
Sbjct: 17886 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17945
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G+E+W V C V L +G FRV N G+S+P L PV +++
Sbjct: 17946 MQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 18003
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDF 893
P ++LP + TY + GE L + +P G+PRP + W K G PL T+RV+V +
Sbjct: 18004 TIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETAT 18060
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
TV +++ + D G+Y ++ T + + V+EK GPP+ V EV ++
Sbjct: 18061 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 18120
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ P G +I Y V+K D T W V T+ ++ L G EY FR++ EN
Sbjct: 18121 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRY 18180
Query: 1013 GLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC 1069
G S DS V + G PF +M ++ P+ D G + +
Sbjct: 18181 GKSAPLDSKAVIVQYP-FKEPGPPGTPFVTSISKDQMLVQWHEPVND-----GGTKIIGY 18234
Query: 1070 AVRGHPKPKVVWMKNKMEIREDPKFLIT 1097
+ K ++W+K +D KF T
Sbjct: 18235 HLEQKEKNSILWVKLNKTPIQDTKFKTT 18262
Score = 261 bits (668), Expect = 2e-69
Identities = 175/561 (31%), Positives = 269/561 (47%), Gaps = 37/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+ G ++R S+R+T+ + KL I + D G+YT + S IKV
Sbjct: 23467 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 23521
Query: 531 EYVPKQEPPK--IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKG---DE 583
+ K PP I +D TS ++I+ EPP + L G ++
Sbjct: 23522 IILDKPGPPTGPIKIDEIDATS---------------ITISWEPPELDGGAPLSGYVVEQ 23566
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--VGEDVASIFLQV---VDV 638
G + + V S+F +E + + TN +G + S ++ + +
Sbjct: 23567 RDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRI 23626
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PPE ++I V D L W PP DGG VTGY+VERK+ + RW+++N T T Y
Sbjct: 23627 PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRY 23686
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
ST + EG+ YE RV A+NA G +PS +KP + PIAP +P + V D T T+ +L
Sbjct: 23687 RSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 23746
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
W P G + GYL+E EW NT P + +T+ +LP GA FRV+ N
Sbjct: 23747 AWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACN 23806
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
G EPA + V + E+ E P L ++ + G + L +P +GKP P WT
Sbjct: 23807 AGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWT 23866
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K G + + R + TS+ T +++A R DSG Y+L ++ + K I++RV+
Sbjct: 23867 KEGQDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNS 23925
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + V W+ P DDG ++I+GY +++ + W+ + R R TS V
Sbjct: 23926 PEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVK 23985
Query: 995 DLIVGNEYYFRVYTENICGLS 1015
L EY+FRV EN G+S
Sbjct: 23986 GLKENVEYHFRVSAENQFGIS 24006
Score = 252 bits (644), Expect = 1e-66
Identities = 177/599 (29%), Positives = 286/599 (47%), Gaps = 32/599 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ VKA E +++ + W K+G+E+ R I L + D D G
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTG 19553
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A + S +N + + K PP L+ +G T+E + + + + D
Sbjct: 19554 QYVLTLKNVAGTRSVAVN-----CKVLDKPGPPAGPLEINGLTAEKCSL--SWGRPQEDG 19606
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--V 624
+ V +T EG ++ +S + + +E + + N V
Sbjct: 19607 GADIDYYIVEKRETSHLAWTICEGELQM------TSCKVTKLLKGNEYIFRVTGVNKYGV 19660
Query: 625 GEDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKG 681
GE + S+ ++ +D VP PP ++ ITSV ++ L W P DGG ++GY++ER++K
Sbjct: 19661 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19720
Query: 682 SQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPT 737
S RW+++N + + +ST + EG YE RV+A NA G+S PS T P + P+
Sbjct: 19721 SLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPS-ETSPLIRAEDPVFLP 19779
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
S P + D TT T+ W P G I GY VEY +W + + + +T
Sbjct: 19780 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYT 19838
Query: 798 VKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQ 857
+ L TGA +FRV VN G S+P+ + P +E E P + +R+T I K G
Sbjct: 19839 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19898
Query: 858 LNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ VPF+G+P P V+W+K L T R +V T+D T + A R+DSG+Y L++Q
Sbjct: 19899 FTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNV 19957
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ T+ ++V++ GPP N+ V++V +A++ W P++DG + + Y ++K +
Sbjct: 19958 LSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKK 20017
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
W +V S V++L G YYFRV EN G+ G+ T +K IT KP
Sbjct: 20018 AWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV----GIPAETKEGVK--ITEKP 20070
Score = 249 bits (637), Expect = 8e-66
Identities = 181/600 (30%), Positives = 287/600 (47%), Gaps = 38/600 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
LTVKA V + + T W K+G ++P++ I ++ L + V +D G
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 13059
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
DYT + + S SA IK++ + K PP V NK+ D
Sbjct: 13060 DYTITAENSSGSKSAT-----IKLKVLDKPGPP---------------ASVKINKMYSDR 13099
Query: 567 SITGEPPPVA------TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
++ PP+ T D+ T+ ++ V +S +E E ++ I
Sbjct: 13100 AMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICA 13159
Query: 621 TNP--VGEDVASIFLQVVDVPDPP---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N VG+ V + + DPP + I+++ +D + W+PP DGG P+TGYL+
Sbjct: 13160 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLL 13219
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
E+++ + W K+N + E T ++T + EG YE RV A+N G +PS +K
Sbjct: 13220 EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARD 13279
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT-EPV 791
P P P V D T ++ +L W P G I GYLVE S+ WV N + +
Sbjct: 13280 PQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13339
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
++ F V L + FRV VN G S+P+ + ++I PP+ L LR+T I
Sbjct: 13340 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 13399
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEY 910
+ G + L VP +G+P P++ W+K L D + ++++DFDT + D+G+Y
Sbjct: 13400 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13459
Query: 911 ELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ 970
L+++ K TI ++V++ GPP+NV VKE+ +A V W+ P DG S I+ Y VQ
Sbjct: 13460 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 13519
Query: 971 KADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKT 1030
K D + W V TS V++L G Y+FRV+ EN G+ D PG +++ + +T
Sbjct: 13520 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD-PGETRDAVKASQT 13578
Score = 246 bits (628), Expect = 9e-65
Identities = 155/494 (31%), Positives = 245/494 (49%), Gaps = 17/494 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
+E + P + LD S + + IVV AG +R+ ++G+PPP TW + T
Sbjct: 10208 IEMKDRLVSPDLQLDASVR---DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER---TLP 10261
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT- 648
IE SS VI++ QR +G Y++ N GE +I + V+DVP P +
Sbjct: 10262 QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAH 10321
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
++ + L W P DGG P+T Y++E+++ + W + + V T +I+G
Sbjct: 10322 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV-TRQNATVQGLIQGKA 10380
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y R+ A N+IG+ P + T + PI P L V++VT T TL W PP G
Sbjct: 10381 YFFRIAAENSIGMG-PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDG 10439
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I Y++E L G+E++ + + +TVK L G +RV VNI G+ +P+
Sbjct: 10440 GSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF 10499
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAP-LDT 883
+P+T ++ PP + L R +VGE L + GKP+P+V W K A L+
Sbjct: 10500 CTKPITCKDELAPPTLHL--DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLED 10557
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVK 942
R H++T+ +A RSDSG+Y + V+ ++ VV++ GPP+ V
Sbjct: 10558 DRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFD 10617
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
EV ++ W+ P DDG S+I Y ++K + W V + T+C VS L+ G +Y
Sbjct: 10618 EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 10677
Query: 1003 YFRVYTENICGLSD 1016
FR++ EN+ G+SD
Sbjct: 10678 IFRIHAENLYGISD 10691
Score = 246 bits (627), Expect = 1e-64
Identities = 150/488 (30%), Positives = 235/488 (48%), Gaps = 9/488 (1%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
++E V + E P + L + + + AG LRL VS++G PPPV TW K
Sbjct: 23129 EIEPVERIEIPDLEL---ADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQG---IDL 23182
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
R I+ S +++ R D G+YTI+ N G+ A++ ++V D P P +V++
Sbjct: 23183 ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVK 23242
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V D + WE P DGG PV Y+VE K++ + R K ++T Y + ++EG +
Sbjct: 23243 EVSRDSVTITWEIPTIDGGAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTM 23301
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y RV N G+ +P + + P L V DVT +T TL W P G +
Sbjct: 23302 YYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRL 23361
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
GY++E C G+E W+ T TV +L G + LFR+ N G SEP
Sbjct: 23362 TGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 23421
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVH 887
VT++++ P I L ++T G + LV+P G+P P W G+ L ++ RV
Sbjct: 23422 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 23481
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWG 946
V T +R+ D+GEY L ++ + TI++ +++K GPP + + E+
Sbjct: 23482 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 23541
Query: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRV 1006
T+ + W+ P+ DG + + GY V++ D W V E ++ + L GNEY FRV
Sbjct: 23542 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 23601
Query: 1007 YTENICGL 1014
N G+
Sbjct: 23602 AATNRFGI 23609
Score = 243 bits (620), Expect = 8e-64
Identities = 162/502 (32%), Positives = 240/502 (47%), Gaps = 27/502 (5%)
Query: 527 EIKVEYVPKQ--EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEV 584
E+K PK+ EPP+I LD S + ++V AG +RL + G P P TW K
Sbjct: 12285 ELKEAIKPKEILEPPEIDLDASMR---KLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID 12341
Query: 585 FTTTEGRTRIEKRVDCSSF-VIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
+G+ + VD +F VI ++ R+D G+Y++ + NP GE + ++V+D P P
Sbjct: 12342 NVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVS 12398
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++++ V + + W PP DGG VT Y+VE+++ + W + EV +T++ T +
Sbjct: 12399 DLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNL 12457
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSE---PLHLIVEDVTDTTTTLKWRPP 760
+ G Y RV AVN G P+ KP + P SE P L V ++T + TL W PP
Sbjct: 12458 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 12517
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANT----EPVERCGFTVKNLPTGARILFRVVGVNI 816
R G IDGY+ Y EE PA+ V+ V L G + FRV N
Sbjct: 12518 LRDGGAKIDGYITSY----REEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNA 12573
Query: 817 AGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P +E PPKI +P + K G++L + GKP P W K
Sbjct: 12574 VGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKK 12629
Query: 877 GGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G + T S + V +D ++ ++ R DSG Y L+ + + DT I++ V++ GP
Sbjct: 12630 GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGP 12689
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + W P +DG S I Y V+K D +W TSC V
Sbjct: 12690 PQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVG 12749
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
LI G EY FRV EN G+S+
Sbjct: 12750 KLIPGQEYIFRVRAENRFGISE 12771
Score = 239 bits (610), Expect = 1e-62
Identities = 152/487 (31%), Positives = 236/487 (48%), Gaps = 22/487 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P I LD + N + AG LRL V I G P P W K D G R
Sbjct: 16631 KLEAPDIDLDLELRKIIN---IRAGGSLRLFVPIKGRPTPEVKWGKVD-------GEIRD 16680
Query: 595 EKRVDCSS----FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSV 650
+D +S V+++ R D G+YT+ + N G A + ++V+D P PP +++T +
Sbjct: 16681 AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEI 16740
Query: 651 GEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYE 710
+D + WEPP+ DGG + Y+VE+++ + + + + +++ ++ EG Y
Sbjct: 16741 TKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCH-KNSWKIDQLQEGCSYY 16799
Query: 711 MRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDG 770
RV A N G+ P+ P P + V+DVT + +L W P G I
Sbjct: 16800 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 16859
Query: 771 YLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
Y+VE + SE+W + V+ + NL G LFRVV VN GRS+P +LA P+
Sbjct: 16860 YIVEMQAKHSEKW--SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIV 16917
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVR 889
+++ P + + +Y +VG+ L + VP G+P+P + WTK G PL T+R++V
Sbjct: 16918 AKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 16974
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTN 948
S T +++ + D G+Y ++V + TA+I I ++K PP V +V +
Sbjct: 16975 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES 17034
Query: 949 ALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYT 1008
+ W P G +I Y VQK D T W V T+ V+ L G EY FR++
Sbjct: 17035 ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFA 17094
Query: 1009 ENICGLS 1015
EN G S
Sbjct: 17095 ENRYGQS 17101
Score = 238 bits (607), Expect = 2e-62
Identities = 178/616 (28%), Positives = 277/616 (44%), Gaps = 39/616 (6%)
Query: 429 EAELIVEEKQLEVLQDIA---DLTVKASEQAVFKCEVSDEK-VTGKWYKNGVEVRPSKRI 484
EAE + E K+ + I +T+KA ++ + V + T KW K EV S +
Sbjct: 12581 EAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL 12640
Query: 485 TISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLD 544
+ L+I DV +D G Y+ + S+ + +IKV + PP+ D
Sbjct: 12641 AVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKVVVMDAPGPPQPPFD 12695
Query: 545 CSGKTSENA-----IVVVAGNKLRLDVSITGEPPPVATWLKGDEVF---TTTEGRTRIEK 596
S ++ I + G +IT +GD V + T+ R+ K
Sbjct: 12696 ISDIDADACSLSWHIPLEDGGS-----NITNYIVEKCDVSRGDWVTALASVTKTSCRVGK 12750
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ E R+ I + VA VP P+ R+T V +D
Sbjct: 12751 LIPGQEYIFRVRA---ENRFGISEPLTSPKMVAQF---PFGVPSEPKNARVTKVNKDCIF 12804
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
+ W+ P DGG P+ GYL+ERK++ S W+K N + T Y ++EG+ Y R++A+
Sbjct: 12805 VAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 12864
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G S PS T+ P P V DVT +T +L W P G I GY VE C
Sbjct: 12865 NKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC 12924
Query: 777 LEGSEEWVPANTEP--VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
++WV NT P + + +T L A+ FR + S P+ + PVTI
Sbjct: 12925 KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE 12984
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA---PLDTSRVHVRTS 891
PP+I L ++ K G + L GKP P V W K G P + ++ ++ +
Sbjct: 12985 NVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN 13044
Query: 892 DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALV 951
F R DSG+Y ++ + + +ATI+++V++K GPP +V + +++ A++
Sbjct: 13045 LCTLELF--SVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAML 13102
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P +DG SEI Y V K + W V TSC+V LI G+EY FR+ EN
Sbjct: 13103 SWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENK 13162
Query: 1012 CGLSD----SPGVSKN 1023
G+ D P ++KN
Sbjct: 13163 YGVGDPVFTEPAIAKN 13178
Score = 238 bits (606), Expect = 3e-62
Identities = 157/496 (31%), Positives = 232/496 (46%), Gaps = 19/496 (3%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP++ LD + ++ + G+ LRL I G P P TW K D T + RI+
Sbjct: 10909 EPPELILDANMAREQH---IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT---KARIDV 10962
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
S I +A ED G Y++ V NP G S+ + V+D P PP + ++ + +D
Sbjct: 10963 TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 11022
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W+ P+ DGG +T Y+VER+ S +W L+ + ++ + + EG Y RV A
Sbjct: 11023 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAE 11081
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G KP P+ P P L DV T +L W P+R G I GYLV
Sbjct: 11082 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11141
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
EY EG+++W+ T C V L G FRV NI G P T P+ +E
Sbjct: 11142 EYQEEGTQDWIKFKTVTNLEC--VVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 11198
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH-VRTSD 892
PP + L L + + K G + +G P P WT G+ + T + V T +
Sbjct: 11199 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11258
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALV 951
F +V ++ R D+GEY+++V T + + V++ GPP + + +V + +
Sbjct: 11259 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11318
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
WQ PKDDG S ++ Y V+K D + W V + T + L G EY FRV EN
Sbjct: 11319 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 11378
Query: 1012 CG----LSDSPGVSKN 1023
G L +P V+K+
Sbjct: 11379 IGVGPPLDSTPTVAKH 11394
Score = 234 bits (598), Expect = 3e-61
Identities = 149/496 (30%), Positives = 239/496 (48%), Gaps = 18/496 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
VE V ++ P LD + + +VV AG +R+ V I G P P TW K + +
Sbjct: 14460 VEIVEREMAPDFELDAELRRT---LVVRAGLSIRIFVPIKGRPAPEVTWTKDN---INLK 14513
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
R IE + +I R D G++ + + NP G+ + ++V+D P P +R T
Sbjct: 14514 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTD 14573
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ +D L W+ P+ DGG +T Y+VE+++ + + + + TY+ T + EG Y
Sbjct: 14574 ITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH-KCTYKVTGLSEGCEY 14632
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
RV A N G+ +P+ T+P S P L + D+T +T +L W P G I
Sbjct: 14633 FFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKIT 14692
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
GY++E +GS++W T C V+NL G F+V+ VN AGRS P ++PV
Sbjct: 14693 GYVIEAQRKGSDQWTHITTVKGLEC--VVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPV 14749
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHV 888
++E P++ L ++ I K G+ + + +P G+P+P V W KG L T RV+
Sbjct: 14750 IVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNF 14809
Query: 889 RTSDFDTVFFVRQAARSDSGEYELSVQ--IENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
T+ T+ + + RSDSG Y L+ + + + D TI++ + GPP + EV
Sbjct: 14810 ETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI--PGPPTGPIKFDEVS 14867
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
W P++DG I Y V+ + W + T+ + L G EY FR
Sbjct: 14868 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 14927
Query: 1006 VYTENICGLSDSPGVS 1021
V +N G+ PG++
Sbjct: 14928 VKAQNRYGV--GPGIT 14941
Score = 232 bits (592), Expect = 1e-60
Identities = 161/551 (29%), Positives = 248/551 (45%), Gaps = 28/551 (5%)
Query: 469 GKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
G W+K E R T++ + G +K + + +GD V
Sbjct: 21993 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG------------- 22039
Query: 527 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 586
++ V + P++ +D + K + VV AG +RL ++ G P P A W K D +
Sbjct: 22040 --TIKAVDRLTAPELDIDANFKQTH---VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 22094
Query: 587 TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVR 646
R I S+ +E+ R D G+YT+ V N G + ++V+D P PP +
Sbjct: 22095 L---RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPIT 22151
Query: 647 ITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEG 706
V A L+W+ P+ DGG + Y+VE+++ + W ++ E T ++ + EG
Sbjct: 22152 FKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDLAEG 22210
Query: 707 ILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAG 766
+ Y RV AVN GV +P +P + + P L V D + ++ L W P+ G
Sbjct: 22211 VPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGS 22270
Query: 767 GIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA 826
I GYL+E +GS+ WV A ++ FTV+ L FRV N AG SEP
Sbjct: 22271 RITGYLLEMRQKGSDFWVEAG--HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 22328
Query: 827 QPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSR 885
V I+E P L Q K G + VP G+P P+V W L +T R
Sbjct: 22329 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDR 22388
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
V + T+ T V+ + R DSG Y L+++ T ++ + V+ + GP + V V
Sbjct: 22389 VSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV 22448
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
+ ++ W PKD G +EI Y V+K + T W V + T V+ L EY F
Sbjct: 22449 SAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSF 22508
Query: 1005 RVYTENICGLS 1015
RV +EN G+S
Sbjct: 22509 RVSSENRFGVS 22519
Score = 231 bits (588), Expect = 4e-60
Identities = 141/480 (29%), Positives = 230/480 (47%), Gaps = 7/480 (1%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ + V+ N + + V TG P P ATW GD+V T + R +++ + VI ++R
Sbjct: 7096 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD-RVKMKTLSAYAELVISPSER 7154
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
D+G YT+K+ N V I + V+ P P+ ++ + +D L WEPP DGG P+
Sbjct: 7155 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7214
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
TGY+VE+++ + W K+ + T+ + +++G Y +V A N G +P+ +P
Sbjct: 7215 TGYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEP 7273
Query: 731 FMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPAN 787
P + P ++ D T + L W PP G I GY+VE C GS++WV
Sbjct: 7274 VNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 7333
Query: 788 TEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
EPV V L G +RV +N G S+P+ + + + E P+I L L
Sbjct: 7334 -EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL 7392
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSD 906
K G ++ L GKP P++ WTK L R+ + + + + RSD
Sbjct: 7393 AGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSD 7452
Query: 907 SGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966
+G Y + + TA + + V++K GPP + +V + L+ W P+DDG S+I
Sbjct: 7453 TGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7512
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y V++ + W + + T+ + LI EY FRV EN+ G+ + S TA+
Sbjct: 7513 YVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAK 7572
Score = 228 bits (581), Expect = 3e-59
Identities = 138/484 (28%), Positives = 226/484 (46%), Gaps = 11/484 (2%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
++E P +D + + ++V AG + V G P P W K D T R +
Sbjct: 19875 REEEPLFDIDSEMRKT---LIVKAGASFTMTVPFRGRPVPNVLWSKPD---TDLRTRAYV 19928
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ +S IE+A R D G+YT+ + N + ++ ++V+D P PP + + V ++
Sbjct: 19929 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKES 19988
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A+L W+ P DGG PV Y +E+++ + W+ + +Y+ T + EG +Y RV
Sbjct: 19989 AVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKVTNLQEGAIYYFRVS 20047
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N GV P+ + S P L V ++ + +L W P G I Y+VE
Sbjct: 20048 GENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVE 20107
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G + WV + V L + FRV N AG S+P L PV I+E
Sbjct: 20108 ALEKGQKNWVKCAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQ 20165
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDF 893
EPP+I + T + G L + +P GKP P+V ++ G PL T R + +
Sbjct: 20166 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20225
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+ ++++ +D+G YE++ + A I I V+++ GPP V++ ++ + ++
Sbjct: 20226 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLK 20285
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ PK DG S++ Y + K + T W V T V L G EY FR+ EN
Sbjct: 20286 WEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRF 20345
Query: 1013 GLSD 1016
G+SD
Sbjct: 20346 GISD 20349
Score = 226 bits (577), Expect = 7e-59
Identities = 133/383 (34%), Positives = 202/383 (52%), Gaps = 10/383 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE-VFTET 696
VPD P+ +T V +D A++ W P +DGGKP+T Y++E+++ S+RW ++ + + T
Sbjct: 10706 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 10764
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTT 753
+ ++EG YE RV A N IG+ PS +KP PIA S P++ D T +
Sbjct: 10765 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10824
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT---VKNLPTGARILFR 810
L W+PP G I GY+VEY G EEW AN P E C T V L G FR
Sbjct: 10825 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTP-ESCPETKYKVTGLRDGQTYKFR 10883
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V+ VN AG S+PA + +PV +++ EPP++ L ++ + KVG+ L L +G P P
Sbjct: 10884 VLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP 10943
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
+V W K T + + + + +R AA D G Y L+V+ T ++++ V+
Sbjct: 10944 KVTWKKEDRDAPT-KARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVL 11002
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTS 990
+K GPP ++ V E+ + + W+ P DDG S I Y V++ D + +W + ++ S
Sbjct: 11003 DKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKS 11062
Query: 991 CTVSDLIVGNEYYFRVYTENICG 1013
L GN+Y FRV EN G
Sbjct: 11063 HFAKHLNEGNQYLFRVAAENQYG 11085
Score = 225 bits (574), Expect = 2e-58
Identities = 147/490 (30%), Positives = 230/490 (46%), Gaps = 22/490 (4%)
Query: 534 PKQE----PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK--GDEVFTT 587
PK E PP+I LD + + + A LRL V I G P P W + G+ +
Sbjct: 15544 PKAEDRMLPPEIELDADLR---KVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--- 15597
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ IE + ++ + R D G+Y + V N G A + ++V+D P PP+ +++
Sbjct: 15598 --DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKV 15655
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
V + L W+PP+ DGG + Y+VE+++ + + + +T+++ ++ EG
Sbjct: 15656 KEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCH-KTSWKVDQLQEGC 15714
Query: 708 LYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
Y RV A N G+ P+ + P + + DVT + +L W P G
Sbjct: 15715 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSR 15774
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
I GY+VE +GS++W T V T+ L G FRV N G S+P L+
Sbjct: 15775 ILGYIVEMQTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSV 15832
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRV 886
PV +++ PP +L L T+ GE L + VPF G+P P V W K PL T+RV
Sbjct: 15833 PVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRV 15889
Query: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
+ +++ +++ ++ A R D G Y + + + T+ + V++K GPP V + EV
Sbjct: 15890 NAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT 15949
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
+ + W PK DG S I Y V+K D T W V T+ L G EY FR
Sbjct: 15950 ADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 16009
Query: 1006 VYTENICGLS 1015
+ EN G S
Sbjct: 16010 IAAENRYGKS 16019
Score = 219 bits (557), Expect = 2e-56
Identities = 145/484 (29%), Positives = 237/484 (48%), Gaps = 18/484 (3%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE-K 596
PP+ LD + + +++ AG +RL V + G PPP TW K + R ++ K
Sbjct: 13385 PPEGELDADLRKT---LILRAGVTMRLYVPVKGRPPPKITWSKPN---VNLRDRIGLDIK 13438
Query: 597 RVDCSSFV-IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
D +F+ E+ + D G+Y + + N G+ +I ++V+D P PP V + + +D A
Sbjct: 13439 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13498
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WEPP+ DGG P+ Y+V+++ + W + E ++T++ + EG Y RVFA
Sbjct: 13499 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFA 13557
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPL-HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N G+ P T+ + + T P+ L V V+ ++ ++ W+ P+ G I GY+V+
Sbjct: 13558 ENEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 13616
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+ E ++ + ++ ++ K+L G FRV N G P+ + V R+
Sbjct: 13617 FLTEENKWQRVMKSLSLQ---YSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDD 13671
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDT-SRVHVRTSDF 893
P + L Y+ K L +P +GKP P V W KG PL T +RV V +S
Sbjct: 13672 VVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAV 13731
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+T V +SD+G+Y ++++ TI I+VV K G P + EV ++
Sbjct: 13732 NTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLK 13791
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W PKDDG SEI Y ++K D +W + T+ V+ L G EY FRV EN
Sbjct: 13792 WAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKY 13851
Query: 1013 GLSD 1016
G+ +
Sbjct: 13852 GVGE 13855
Score = 218 bits (556), Expect = 2e-56
Identities = 158/516 (30%), Positives = 233/516 (45%), Gaps = 54/516 (10%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+++ V QE P+I LD + V AG K+ L ++TG+P P TW K D +
Sbjct: 7373 EIQAVDTQEAPEIFLDVKLLAG---LTVKAGTKIELPATVTGKPEPKITWTKADMILKQD 7429
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
+ R IE S+ I ++R D G Y I+ N G A + + V+D P PP A IT
Sbjct: 7430 K-RITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDIT 7488
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V + +L W PP DGG +T Y+VER+ S+ W KL+ V +T +++TK+I
Sbjct: 7489 DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKLIPNKE 7547
Query: 709 YEMRVFAVNAIGVSQPSMNTKPF---MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGA 765
Y RV A N GV +P + P P P L D+T TL W P+ G
Sbjct: 7548 YIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7606
Query: 766 GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATL 825
I GY VE +++WV N PV+ + VK L + FRV+ N+AG +P+
Sbjct: 7607 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7666
Query: 826 AQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPL 881
+P+ I++ +PP V GK ++ WTK GGA +
Sbjct: 7667 TEPILIKDPIDPP----------------WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKI 7710
Query: 882 DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG------- 934
++ + + + D +VR A + ++ L +E + + R+R V KAG
Sbjct: 7711 ESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQE--YSFRVRAVNKAGESEPSEP 7766
Query: 935 --------------PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF 980
PP + V + A ++W P+ DG S I Y V+K D + W
Sbjct: 7767 SDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQ 7826
Query: 981 NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T CTV+ L G+ Y FRV EN G SD
Sbjct: 7827 TVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7862
Score = 218 bits (556), Expect = 2e-56
Identities = 180/670 (26%), Positives = 295/670 (44%), Gaps = 50/670 (7%)
Query: 364 EMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVIT 423
E VE +G Q W G+ T E + ++ +L F + ++G +T
Sbjct: 21191 EYVVERKGKGEQT-WSHAGISKTCE------IEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21243
Query: 424 NGGQCEAELIVEEKQLEVLQDI--ADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRP 480
G ELI+ + L DI A +TV+ + + K + W K+G+ ++
Sbjct: 21244 IGPITVKELIITPEV--DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21301
Query: 481 SKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPK 540
S+ + S L I + + E G YT + D ++ + + + PK
Sbjct: 21302 SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP--- 21358
Query: 541 IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGR--TRIEKRV 598
+ ++++ D I P G+ + E R ++ ++
Sbjct: 21359 ----------------IRFDEIKADSVILSWDVPEDNG-GGEITCYSIEKRETSQTNWKM 21401
Query: 599 DCSS-----FVIESAQREDEGRYTIKVTNPVGED---VASIFL--QVVDVPDPPEAVRIT 648
CSS F + + ++ E ++ ++ N G V+SI + +P PP I
Sbjct: 21402 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY 21461
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
+V D L W+ P+YDGG VTG+ VE+K++ S W K+N + Y +T ++EG+
Sbjct: 21462 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 21521
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y+ RV+A N+ G+S PS +K + ++P P DVT T TLKW PP R G I
Sbjct: 21522 YQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKI 21581
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQ 827
GY +E +G+E WV N V C +TV L G R FR++ N G S P+ +
Sbjct: 21582 VGYSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSG 21640
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH 887
+ R+ PP + I K GE L + QG+P P+V W K G ++ R++
Sbjct: 21641 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMN 21699
Query: 888 VRTSDF--DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
+ +D T FVR A R G Y + + + A I+++V + G + + +
Sbjct: 21700 MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNI 21759
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
G + W AP +DG + I Y ++K + + W + ++ S T LI GNEY F
Sbjct: 21760 TGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQF 21819
Query: 1005 RVYTENICGL 1014
RV N G+
Sbjct: 21820 RVSAVNKFGV 21829
Score = 218 bits (555), Expect = 3e-56
Identities = 160/568 (28%), Positives = 254/568 (44%), Gaps = 31/568 (5%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+K+ V ++ + R+ L I D ED G Y L+ SA + V
Sbjct: 15876 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVV-----KLTNSAGEAIETLNV 15930
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITG-----EPPPVATWLKGDEVF 585
+ K PP + T+++ + K SI TW ++
Sbjct: 15931 IVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW----QIV 15986
Query: 586 TTTEGRTRIEK---RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+ T RT I+ + C + A G+ T + P ++ VP PP
Sbjct: 15987 SATVARTTIKACRLKTGCE-YQFRIAAENRYGKSTYLNSEP------TVAQYPFKVPGPP 16039
Query: 643 EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTK 702
+T D + W P+ DGG V GY +ERK++ S W+KLN +T +++T
Sbjct: 16040 GTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTG 16099
Query: 703 MIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNR 762
+ EG+ YE RV A N +G+ +PS ++ ++ P P VT + TL+W+ P
Sbjct: 16100 LEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTY 16159
Query: 763 IGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSE 821
G I GY+VE W+ A+ + F V L R FRV+ N AG SE
Sbjct: 16160 DGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 16219
Query: 822 PATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL 881
P+ +T R+ +PP+I + + T + GE + GKP P + W KG L
Sbjct: 16220 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16279
Query: 882 -DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-V 939
+T+R+ ++++DF T V+ A R DSG Y L + + + T+ ++V+++ GPP V
Sbjct: 16280 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPV 16339
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVG 999
++ V + W+ P DG S+I+ Y V++ + + W V + SC V+ L+ G
Sbjct: 16340 VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG 16399
Query: 1000 NEYYFRVYTENICG----LSDSPGVSKN 1023
NEY FR+ N G L P V+KN
Sbjct: 16400 NEYTFRIMAVNKYGVGEPLESEPVVAKN 16427
Score = 218 bits (554), Expect = 3e-56
Identities = 167/650 (25%), Positives = 284/650 (43%), Gaps = 55/650 (8%)
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRIT 485
+C+ +L+ +L+V + I L VKA F + V T KW +G E++ + T
Sbjct: 11195 ECQEKLVPPSVELDV-KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11253
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDC 545
+ L I + D G+Y A S + ++ + V PP ++
Sbjct: 11254 VETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP-----GPPTGPINI 11308
Query: 546 SGKTSENAIVVVAGNKLRLDVSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVD 599
T E+ ++I+ +PP PV ++ ++ T + +
Sbjct: 11309 LDVTPEH-------------MTISWQPPKDDGGSPVINYIV-EKQDTRKDTWGVVSSGSS 11354
Query: 600 CSSFVIESAQREDEGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ I Q+ E + ++ N +G + ++ P PP +T + E+
Sbjct: 11355 KTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENA 11414
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A + W P DGG P+TGY +ER++ + +W+++N + + T + EG YE RVF
Sbjct: 11415 ATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVF 11473
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G+S+PS ++ P PI P P++ ++D + T L W P G I GY
Sbjct: 11474 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 11533
Query: 772 LVEYCLEGSEEWVPANT-EPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
+VE G+ +W N E + +C F V L G FR+ NI G EP LA+ V
Sbjct: 11534 VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVI 11593
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRT 890
++I PP++ L R +VG+ + ++ +G+P P + WTK G L +
Sbjct: 11594 AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI 11653
Query: 891 SDFDTV-FFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
D V +++A R+D G+Y +S + + + + V+++ GP N+ V V N
Sbjct: 11654 QDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENC 11713
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W+ P D+G SEI + V+ W ++ + ++L+ NEYYFRV E
Sbjct: 11714 TISWENPLDNGGSEITNFIVEYRKPNQKGW-SIVASDVTKRLIKANLLANNEYYFRVCAE 11772
Query: 1010 NICGLS---------------DSPGVSKNTARILKTGITFKPFEYKEHDF 1044
N G+ D PG +N I G TF +++ D+
Sbjct: 11773 NKVGVGPTIETKTPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDY 11821
Score = 217 bits (553), Expect = 4e-56
Identities = 125/382 (32%), Positives = 192/382 (50%), Gaps = 3/382 (0%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP PP ++T+V +D + W P+ DGG P+ GY VERK++ W ++ +
Sbjct: 14953 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 15012
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKW 757
++S+ + +GI YE RV A N G S+PS ++P + + P P + ++T T TLKW
Sbjct: 15013 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKW 15072
Query: 758 RPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIA 817
P G I Y+VE + W+ AN + FTV L A FRV+ N A
Sbjct: 15073 AKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAA 15132
Query: 818 GR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P+ + +T R+ E PKI++ + T I K GE L G+P P + W+K
Sbjct: 15133 GAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSK 15192
Query: 877 GGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G L+ T+++ ++ +DF T + + R DSG Y L+ ++V+++ GP
Sbjct: 15193 DGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP 15252
Query: 936 PIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + V EV ++ W P DDG ++I Y VQK + + W NV + T V+
Sbjct: 15253 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVT 15312
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 15313 KLLKGNEYIFRVMAVNKYGVGE 15334
Score = 217 bits (552), Expect = 6e-56
Identities = 155/560 (27%), Positives = 257/560 (45%), Gaps = 34/560 (6%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
E P+I LD + +TS ++ AG +++ + G PPP TW K DE ++ R IE
Sbjct: 20962 EAPEIDLDVALRTS---VIAKAGEDVQVLIPFKGRPPPTVTWRK-DEKNLGSDARYSIEN 21017
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS-IFLQVVDVPDPPEAVRITSVGEDWA 655
S I R D G+Y + + N VGE +S + ++V+D P + +++ V
Sbjct: 21018 TDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV 21077
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L+W+PP+ DGG P+ Y++E++ + W ++ + + T+++ + E + RV A
Sbjct: 21078 TLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLA 21136
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY 775
N IG+ +P T+P + L ++D T T+ L W P+ G I Y+VE
Sbjct: 21137 ENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 21196
Query: 776 CLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIA 835
+G + W A + C V L + + FRV N G S+P T+ P+T++E+
Sbjct: 21197 KGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELI 21253
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFD 894
P++ L ++G ++L +P++GKP+P + W K G PL S V ++
Sbjct: 21254 ITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK 21313
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV---VEKAGPPIN----VMVKEVWGT 947
++ A + G+Y + + D A RI V V GPP + E+
Sbjct: 21314 ITLSIKNAKKEHGGKYTV------ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKAD 21367
Query: 948 NALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVY 1007
+ ++ W P+D+G EI Y ++K + W V T+ V +L+ EY FRV
Sbjct: 21368 SVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVR 21427
Query: 1008 TENICGLS----DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGY 1063
EN G+S S V+K+ RI G KP Y M+ + P+ D G
Sbjct: 21428 AENRYGVSQPLVSSIIVAKHQFRI--PGPPGKPVIYNVTSDGMSLTWDAPVYD-----GG 21480
Query: 1064 SAALNCAVRGHPKPKVVWMK 1083
S V + ++W K
Sbjct: 21481 SEVTGFHVEKKERNSILWQK 21500
Score = 216 bits (551), Expect = 8e-56
Identities = 174/617 (28%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 434 VEEKQLEVLQDIADLTV-KASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR 491
VE +++V D + KA E + +VS T +W K+G E+ + ++ I
Sbjct: 15151 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15210
Query: 492 FHKLVIDDVRPEDEGDYTFV---PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
LV D D G YT P G+A + V+ + + PP+ L +
Sbjct: 15211 STNLVNKDSTRRDSGAYTLTATNPGGFAKHI--------FNVKVLDRPGPPEGPLAVTEV 15262
Query: 549 TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF-----TTTEGRTRIEKRVDCSSF 603
TSE + ++ PP K D T+ T + V +
Sbjct: 15263 TSEKCV-------------LSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 15309
Query: 604 VIESAQREDEGRYTIKVTNP--VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILV 658
+ + +E + + N VGE + S + V+ PDPP+ +T++ +D ++
Sbjct: 15310 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVC 15369
Query: 659 WEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
W P DGG + Y+VER+ K QRW+K N + T+ Y+ + + EG YE R+ A NA
Sbjct: 15370 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 15429
Query: 719 IGVSQPSMNTKPFMPIAPT----SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
G+S PS T PF T P + V D + ++ ++ W P G I GY+VE
Sbjct: 15430 AGISAPS-PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVE 15488
Query: 775 YCLEGSEEW-VPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
L +EW + ++ +T+ L R+ +N G EPA + +
Sbjct: 15489 IALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAED 15548
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKG-GAPLDTSRVHVRTSD 892
PP+I L LR+ + L L VP +G+P P+V W + G LD + + TS
Sbjct: 15549 RMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIE-STSS 15607
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVE 952
+ T+ V R DSG+Y L+V+ + +A + +RV++ GPP ++ VKEV T+ +
Sbjct: 15608 Y-TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLT 15666
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W P DG S+I Y V+K + + V TS V L G YYFRV EN
Sbjct: 15667 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEY 15726
Query: 1013 GLSDSPGVSKNTARILK 1029
G+ G+ TA +K
Sbjct: 15727 GI----GLPAETAESVK 15739
Score = 215 bits (548), Expect = 2e-55
Identities = 150/495 (30%), Positives = 223/495 (45%), Gaps = 24/495 (4%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
QEPP + LD S K I ++AG LR+ +TG P P W K E + R I+
Sbjct: 8794 QEPPAVELDVSVK---GGIQIMAGKTLRIPAVVTGRPVPTKVWTK--EEGELDKDRVVID 8848
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S +I+ A R+D GRY I TN G A+ ++V DVP P ++
Sbjct: 8849 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8908
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYESTKMIEGILYEMRVF 714
+L W P DGG +TG+++ERK W + + TE + + T ++EG Y+ RV
Sbjct: 8909 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ---PIETERSKCDITGLLEGQEYKFRVI 8965
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G P + P + P+ P + P L + T +T TL W+ P G I GY
Sbjct: 8966 AKNKFGCG-PPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGY 9024
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
++E ++ N F V+NL FRV VN G SEP +L V I
Sbjct: 9025 IIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-SLPLNVVI 9083
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGA-------PLDT 883
++ PP I+L +R I+ K GE +++ G P P++ W+K L
Sbjct: 9084 QDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQI 9143
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKE 943
++ V S+ T + +A R D G Y ++ + + V ++ PP N+ V +
Sbjct: 9144 TKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9203
Query: 944 VWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIVGNE 1001
+ + + W AP D+G SEI Y + K D +K EW V + LI +
Sbjct: 9204 IKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQ 9263
Query: 1002 YYFRVYTENICGLSD 1016
Y FRV N G+SD
Sbjct: 9264 YEFRVRAVNKYGISD 9278
Score = 213 bits (543), Expect = 6e-55
Identities = 157/584 (26%), Positives = 263/584 (45%), Gaps = 34/584 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
L +K+ E K V V W+K+GVE+ + I+ V L + D + G
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21722
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRL-- 564
YT + S A++ ++KV+ P + I + G K+ L
Sbjct: 21723 VYTVEAKNASGSAKAEI---KVKVQDTPGKVVGPIRF-----------TNITGEKMTLWW 21768
Query: 565 DVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN-- 622
D + P+ ++ ++ T+ IE + + S+ +E ++ + N
Sbjct: 21769 DAPLNDGCAPITHYII-EKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKF 21827
Query: 623 ----PVGED--VASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
P+ D VA I V D P PE IT + L W P DGG + Y++E
Sbjct: 21828 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITG---NSITLTWARPESDGGSEIQQYILE 21884
Query: 677 RKKKGSQRWMK-LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
R++K S RW+K ++ +ET ++ T + EG YE V A NA GV S ++
Sbjct: 21885 RREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE 21944
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
P+ P P + V D + TT +L+W P G I GY++E C +W N E
Sbjct: 21945 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV 22004
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
+ +TV +L G FRV +N AG+ + + + + P++ + + +QT++
Sbjct: 22005 KTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVV 22064
Query: 853 KVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ G + L + +QG+P P VW+K + L + R + T+D + V R+D+G+Y L
Sbjct: 22065 RAGASIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTL 22123
Query: 913 SVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKA 972
+V+ + + T ++V++ GPP + K+V +A + W AP DG + I Y V+K
Sbjct: 22124 TVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKR 22183
Query: 973 DKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + E+ V+DL G YYFRV N G+ +
Sbjct: 22184 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 22227
Score = 213 bits (542), Expect = 8e-55
Identities = 131/391 (33%), Positives = 192/391 (49%), Gaps = 16/391 (4%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PDPPE +T V ++ +VW PP YDGGK +TGY +E+K+K S RW+ +N E
Sbjct: 12094 PDPPE---VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 12150
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
+ ++ Y+ RV A N IG+ +PS+ ++P + PI P P + V D T + TL
Sbjct: 12151 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITL 12210
Query: 756 KWRPPNRIGAGGIDGYLVEYC-----LEGSEEWVPANTEP-VERCGFTVKNLPTGARILF 809
W P G I GY+VE E W N + R FTV +L F
Sbjct: 12211 GWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEF 12270
Query: 810 RVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPR 869
RV N G PA L + + +EI EPP+I L +R+ I + G + L +G+P
Sbjct: 12271 RVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPA 12330
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV 929
P+V W K G + V D + + R DSG+Y L++ + + +RV
Sbjct: 12331 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 12390
Query: 930 VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
++ GP ++ V +V T+ V W P++DG S++ Y V+K + W V + T
Sbjct: 12391 LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKT 12450
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGV 1020
S V++L+ GNEYYFRV N G PGV
Sbjct: 12451 SFHVTNLVPGNEYYFRVTAVNEYG----PGV 12477
Score = 211 bits (538), Expect = 2e-54
Identities = 145/521 (27%), Positives = 236/521 (45%), Gaps = 40/521 (7%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW--------LKGDEVFTT 587
QE P++ +D +++ +V AG+++R+ I G P P ++W D V
Sbjct: 9500 QEEPEVFIDIG---AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDI 9556
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
E ++E + S +I +R G+Y+I N G+ A+ ++V+DVP PP+ +++
Sbjct: 9557 PED-AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKV 9615
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
+ + L W+ P DGG + GY++E++ + W K+N + TT+ ++
Sbjct: 9616 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDC-GSTTFVVPDLLSEQ 9674
Query: 708 LYEMRVFAVNAIGVSQP---SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y RV A N G+ P T PI P P+ L + +T T L W+PP G
Sbjct: 9675 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDG 9734
Query: 765 AGGIDGYLVEYCL------EGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG 818
+ Y+VE CL E W N VE FTV++L G FRV VN AG
Sbjct: 9735 GSPVTHYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAG 9793
Query: 819 RSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
S+P+ P + PP I L + + G +N+V +G P P + W K
Sbjct: 9794 VSKPSATVGPCDCQRPDMPPSIDLKEFMEV----EEGTNVNIVAKIKGVPFPTLTWFK-- 9847
Query: 879 AP----------LDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
AP L + V+ D + Q+ RSD+G Y ++ + +R+
Sbjct: 9848 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9907
Query: 929 VVEKAGPPIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR 987
V+ + GPP+ + + V + W PKDDG S+I Y ++K + W +V +
Sbjct: 9908 VLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPK 9967
Query: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
+ T+ L+ G+EY FR+ +N G+ + TAR L
Sbjct: 9968 ECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 10008
Score = 211 bits (536), Expect = 4e-54
Identities = 160/614 (26%), Positives = 270/614 (43%), Gaps = 45/614 (7%)
Query: 431 ELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHV 489
+L++E +V + +V+ + + +S K T W K+G+ ++ + RI ++
Sbjct: 16920 DLVIEP---DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDS 16976
Query: 490 GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
L I + +D G Y G ++ I++ + K +PPK + +
Sbjct: 16977 LDLTTLSIKETHKDDGGQY-----GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVS 17031
Query: 550 SENAIV-----VVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 604
+E+ + + G + + W +V + T RT ++
Sbjct: 17032 AESITLSWNPPLYTGGCQITNYIVQKRDTTTTVW----DVVSATVARTTLK--------- 17078
Query: 605 IESAQREDEGRYTIKVTNPVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVW 659
+ + E ++ I N G+ A +V P PP T++ +D ++ W
Sbjct: 17079 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 17138
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
P+ +GG PV GY +ERK++ S W K+N + +T +++ + EGI YE RV+A N +
Sbjct: 17139 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 17198
Query: 720 GVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
GV + S N++ ++ P P P ++V+ TL+W P G I GY+VE
Sbjct: 17199 GVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKR 17255
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIA 835
W+ A+ V FTV L R FRV+ N AG S+P+ P+T ++
Sbjct: 17256 DLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEV 17315
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFD 894
E P+I + R T + GE L GKP P + W +G ++ S R ++ +DF
Sbjct: 17316 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17375
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVEW 953
+ V+ A R D G+Y L + + ++V+++ GPP V V V + W
Sbjct: 17376 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 17435
Query: 954 QAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I Y V+K + + W V S V+ L+ GNEY FR+ N G
Sbjct: 17436 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 17495
Query: 1014 ----LSDSPGVSKN 1023
L +P + KN
Sbjct: 17496 VGEPLESAPVLMKN 17509
Score = 210 bits (535), Expect = 5e-54
Identities = 152/568 (26%), Positives = 255/568 (44%), Gaps = 40/568 (7%)
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE 527
T +WYK+ E++ + + + + ++I D + G Y S SA
Sbjct: 20598 TIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT----- 20652
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
I+V+ + K PP ++ T+E +++ PP K
Sbjct: 20653 IRVQILDKPGPPGGPIEFKTVTAEK-------------ITLLWRPPADDGGAKITHYIVE 20699
Query: 588 TEGRTRI------EKRVDCSSFVIESAQ--REDEGRYTIKVTNPVG-----EDVASIFLQ 634
+R+ E +C +I + + + +E + ++ N G E + +
Sbjct: 20700 KRETSRVVWSMVSEHLEEC---IITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKN 20756
Query: 635 VVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT 694
P PP +T + ++ +VW P+ DGG ++GY +E++ K S W K+ E
Sbjct: 20757 AFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR 20816
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDT 751
+T + T + E Y+ RV AVNA G S+PS K PI P P + + D T +
Sbjct: 20817 DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKS 20876
Query: 752 TTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLPTGARILFR 810
+ TL W P G + GY+VE EEW +T+ V + V NL G FR
Sbjct: 20877 SITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFR 20936
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VN AG+ EP + +PV ++I E P+I L LR + I K GE + +++PF+G+P P
Sbjct: 20937 VSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPP 20996
Query: 871 QVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI-ENMKDTATIRIR 928
V W K L + +R + +D ++ + Q R+D+G+Y L+++ ++T+ ++
Sbjct: 20997 TVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVK 21056
Query: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
V++ + VK V + W P DG S I+ Y ++K D W V +
Sbjct: 21057 VLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS 21116
Query: 989 TSCTVSDLIVGNEYYFRVYTENICGLSD 1016
TS + DL ++FRV EN G+ +
Sbjct: 21117 TSFKLIDLSEKTPFFFRVLAENEIGIGE 21144
Score = 209 bits (532), Expect = 1e-53
Identities = 154/579 (26%), Positives = 261/579 (45%), Gaps = 27/579 (4%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK-WYKNGVEVRPSK-RITISHVGRFHKLVIDDVRPEDE 505
+ V A E V + ++ + + W K+G E+ + R+ I + LV+ D D
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G Y LS + I V+ + + PP+ L +G T+E + A N D
Sbjct: 18472 GQYIL-----KLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL--AWNPPLQD 18524
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP-- 623
++ ++ ++ T+ T++ V ++ + +E + + N
Sbjct: 18525 GGAN-----ISHYII-EKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 18578
Query: 624 VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
+GE + S + + P PP ++++ +D ++ W P+ DGG + GY++E++ K
Sbjct: 18579 IGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK 18638
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGV---SQPSMNTKPFMPIAPT 737
RW K N + T+ T + EG YE RV A NA GV S+PS+ + + P
Sbjct: 18639 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP 18698
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-- 795
P + V D + ++ +L W P G + GY+VE ++EW T P G
Sbjct: 18699 GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTC-TPPTGLQGKQ 18757
Query: 796 FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG 855
FTV L FR+ +N G EPATL V +E EPP+I L LR+ + +
Sbjct: 18758 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18817
Query: 856 EQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L L V +G+P P+V W K L T R + + T+ + R DSG Y L+++
Sbjct: 18818 ATLRLFVTIKGRPEPEVKWEKAEGIL-TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 18876
Query: 916 IENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ TA + +RV++ P+N+ ++EV + + W+ P DG ++I Y V+K +
Sbjct: 18877 NNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETT 18936
Query: 976 TMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
+ + T+ + +L G YYFRV N G+
Sbjct: 18937 RKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975
Score = 208 bits (529), Expect = 3e-53
Identities = 149/504 (29%), Positives = 229/504 (45%), Gaps = 42/504 (8%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE 613
I+V+ G KL + V P P +W K + ++ T + V +S R D
Sbjct: 8091 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSV-RADA 8149
Query: 614 GRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGY 673
G YTI + N +G ASI ++V+ +P P + ++ + + + L WEPP +DGG P+ Y
Sbjct: 8150 GIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHY 8209
Query: 674 LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM- 732
++ER++ G + ++ + + ++ +I Y RV AVN +G + P +
Sbjct: 8210 VLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8268
Query: 733 --PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP 790
P P P+ + V + T T+ W+PP G I GY++E +G E W N
Sbjct: 8269 QDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL 8328
Query: 791 VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
V +T K L G FRV N AG SEP+ P + + PK+ LR +
Sbjct: 8329 VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSL 8384
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKG------------GAPLD---------------- 882
K G+++ L G P P + W K APL
Sbjct: 8385 EVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLP 8444
Query: 883 -TSRVHVRTS-DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVM 940
T R+ + S ++ VR + R D G Y + V+ ++ A + V++ GPPIN +
Sbjct: 8445 LTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV 8504
Query: 941 VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIV 998
+++ T+ L +W+ P DDG SEI+ Y ++K D K EW V RH +V+ LI
Sbjct: 8505 FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIE 8564
Query: 999 GNEYYFRVYTENICGLSDSPGVSK 1022
G EY FRV EN G P VSK
Sbjct: 8565 GKEYLFRVRAENRFG-PGPPCVSK 8587
Score = 205 bits (522), Expect = 2e-52
Identities = 154/585 (26%), Positives = 255/585 (43%), Gaps = 40/585 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E + +V + + T +W + E+ S R I + L++ D D G
Sbjct: 17330 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 17389
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A S S +N V+ + + PP+ + +G TSE
Sbjct: 17390 QYILRASNVAGSKSFPVN-----VKVLDRPGPPEGPVQVTGVTSEKC------------- 17431
Query: 567 SITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
S+T PP ++ ++ ++ T+ T + V +S + +E + I
Sbjct: 17432 SLTWSPPLQDGGSDISHYVV-EKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMA 17490
Query: 621 TNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N G E + +P PP+++ +T++ +D + W P DGG + GY+V
Sbjct: 17491 VNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV 17550
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFM 732
E++ + RW+K N T+ T + E YE RV A NA GV +PS T K
Sbjct: 17551 EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD 17610
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW---VPANTE 789
P+ P + + D T + TL W P G I GY+VE C EEW P
Sbjct: 17611 PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17670
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
V R F + L RV +N G E ++ V + E P++ L LR+
Sbjct: 17671 RVTR--FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG 17728
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE 909
+ + G + +PF+G+P P++ W++ T +V + T + R+D+G+
Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGK 17787
Query: 910 YELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFV 969
Y L ++ + +A + ++V++ GPP N+ VKEV +A + W+ P DG +++ Y +
Sbjct: 17788 YILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17847
Query: 970 QKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
K + + NV + TS V +L G YYFRV EN G+
Sbjct: 17848 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 17892
Score = 205 bits (521), Expect = 2e-52
Identities = 150/561 (26%), Positives = 249/561 (44%), Gaps = 34/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W K+G ++ + R+ + L I + +D G YT A + + L+ + ++
Sbjct: 18040 WVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE- 18098
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVF---- 585
K PP + V +++ D V I+ EPP +
Sbjct: 18099 ----KPGPP--------------VGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 18140
Query: 586 -TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVP 639
TTT + V ++ I + E ++ I N G+ D ++ +Q P
Sbjct: 18141 DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 18200
Query: 640 DPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYE 699
PP +TS+ +D ++ W P+ DGG + GY +E+K+K S W+KLN +T ++
Sbjct: 18201 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18260
Query: 700 STKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
+T + EG+ YE +V A N +G+ +PS ++ F+ P P +T TLKW+
Sbjct: 18261 TTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKK 18320
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G I GY+VE W+ A+ V FTV L R FRV+ N AG
Sbjct: 18321 PAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGN 18380
Query: 820 -SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
SEP+ + +T R+ + P L + + GE L +GKP P VVW+K G
Sbjct: 18381 FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDG 18440
Query: 879 APLD--TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
L+ +R+ ++++ T V+ R+D G+Y L + + I ++V+++ GPP
Sbjct: 18441 KELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPP 18500
Query: 937 IN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+ V V + W P DG + I Y ++K + + W V + + V+
Sbjct: 18501 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTK 18560
Query: 996 LIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 18561 LLPGNEYIFRVMAVNKYGIGE 18581
Score = 204 bits (519), Expect = 4e-52
Identities = 159/589 (26%), Positives = 267/589 (45%), Gaps = 45/589 (7%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
LT+KA + V K K W K G ++RPS I+ L I +D
Sbjct: 14083 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDA 14142
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G+YT K+ +++ V VP P ++ S ++E A
Sbjct: 14143 GEYTITATN---PFGTKVEHVKVTVLDVPGPPGP---VEISNVSAEKA------------ 14184
Query: 566 VSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619
++T PP P+ +++ ++ T+ T + + + V + +E + +
Sbjct: 14185 -TLTWTPPLEDGGSPIKSYIL-EKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVS 14242
Query: 620 VTNPVG--EDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL 674
N G E V S +++VD P PPE +++V ++ A + W+ P+ DGG +TGY
Sbjct: 14243 AVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYH 14302
Query: 675 VERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-- 732
VER++K S RW++ ++ + T + EG YE RV A N G+ PS + +
Sbjct: 14303 VERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMK 14362
Query: 733 ----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
P P S P V D T + +L W P+ G I GY+VE+ G E W+ T
Sbjct: 14363 DAAYPPGPPSNPH---VTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTT 14419
Query: 789 EPVERCG-FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
R F V +L T + FR+ +N AG EPA + V I E P L LR
Sbjct: 14420 GTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAELR 14478
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDS 907
+T + + G + + VP +G+P P+V WTK L +R ++ ++ T+ + + R D+
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRYDT 14537
Query: 908 GEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGY 967
G++ ++++ K + + +RV++ GP +N+ ++ + + W P DG S I Y
Sbjct: 14538 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNY 14597
Query: 968 FVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V+K + + + + V+ L G EY+FRV EN G+ +
Sbjct: 14598 IVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14646
Score = 203 bits (517), Expect = 7e-52
Identities = 166/605 (27%), Positives = 260/605 (42%), Gaps = 40/605 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E ++ + + T +W K E+ + R+ I L + D D G
Sbjct: 16248 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16307
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV-----VVAGNK 561
+Y A S +N V+ + + PP+ + SG T+E + + G
Sbjct: 16308 NYILKAKNVAGERSVTVN-----VKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGS 16362
Query: 562 LRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVT 621
++ + W T ++ V S + +E + I
Sbjct: 16363 DIINYIVERRETSRLVW-------------TVVDANVQTLSCKVTKLLEGNEYTFRIMAV 16409
Query: 622 NP--VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
N VGE + S + VPD P+A +T+V +D I+VWE P DGG + GY++E
Sbjct: 16410 NKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLE 16469
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFMP 733
++ K RW + + + E T +IE YE RV A NA G+S+PS + K P
Sbjct: 16470 KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDP 16529
Query: 734 IAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP--V 791
I P + V D+T ++ L W P G I GY+VE C EW T P +
Sbjct: 16530 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMC-TPPTGI 16588
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
+ V+ L FR+ +N AG E A + P+ + E E P I L LR+
Sbjct: 16589 NKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 16648
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
+ G L L VP +G+P P+V W K + + + TS F T + R DSG+Y
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF-TSLVLDNVNRYDSGKYT 16707
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
L+++ + +A + +RV++ PP+N+ V E+ + + W+ P DG S+I Y V+K
Sbjct: 16708 LTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 16767
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
+ + V S + L G YYFRV EN G+ G+ TA +K
Sbjct: 16768 REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI----GLPAQTADPIKVA 16823
Query: 1032 ITFKP 1036
+P
Sbjct: 16824 EVPQP 16828
Score = 203 bits (516), Expect = 9e-52
Identities = 157/575 (27%), Positives = 257/575 (44%), Gaps = 39/575 (6%)
Query: 462 VSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
V D V GK W K E+ +++++ + G+ VI D G YT
Sbjct: 22761 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22820
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
+ K + +KV LD G + + V K L S+ E
Sbjct: 22821 S---GTKAVSVMVKV------------LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA 22865
Query: 576 A-TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
T + T+ +E S+V+ + +E + ++ N G V
Sbjct: 22866 EITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP 22925
Query: 635 VV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLN 689
+V +P PP G++ I+ W P DGG ++ YLV++++K S RW ++N
Sbjct: 22926 IVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVN 22985
Query: 690 FE-VFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
+ V +T + T ++EG Y+ RV AVNA G S+PS + +P P S P
Sbjct: 22986 KDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPR- 23044
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP-VERCGFTVKNL 801
V D T + +L W P G I GY++E + +++W +T + FTV +L
Sbjct: 23045 --VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDL 23102
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G + FRV VN+ G SE + + E E P + L L++T + G L L+
Sbjct: 23103 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM 23162
Query: 862 VPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKD 921
V G+P P + W+K G L SR + T++ ++ V + R D+G+Y + + ++ K
Sbjct: 23163 VSVSGRPPPVITWSKQGIDL-ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23221
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
+AT+ ++V + GP +V VKEV + + W+ P DG + + Y V+K + +
Sbjct: 23222 SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKT 23281
Query: 982 VYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T +S L+ G YYFRV ENI G+ +
Sbjct: 23282 VTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23316
Score = 202 bits (515), Expect = 1e-51
Identities = 126/404 (31%), Positives = 190/404 (47%), Gaps = 12/404 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP P+ ++SV + + WE P YDGG PVTGY +E K S+RW ++N + T
Sbjct: 10011 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 10070
Query: 698 ----YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTD 750
Y+ T +IEG Y+ RV+A+NA GV S+ + P PIAP P + D T
Sbjct: 10071 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVT-DWTK 10129
Query: 751 TTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
++ L+W PP + G + GY+VEY EG EEW + V V L GA FR
Sbjct: 10130 SSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFR 10189
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VNIAG EP + + +++ P ++L +R + G + ++ GKP P
Sbjct: 10190 VRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP 10249
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
V W L + T+ + ++ RS G Y L + E + TI + V+
Sbjct: 10250 TVTWNMNERTL-PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 10308
Query: 931 EKAGP-PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
+ GP + + + + W +P+DDG S I Y ++K + W V
Sbjct: 10309 DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ 10368
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
+ TV LI G Y+FR+ EN G+ P V + A +++ IT
Sbjct: 10369 NATVQGLIQGKAYFFRIAAENSIGM--GPFVETSEALVIREPIT 10410
Score = 201 bits (510), Expect = 4e-51
Identities = 227/907 (25%), Positives = 363/907 (40%), Gaps = 108/907 (11%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V ++ E++ KWF+N + I SSKY+ L I L D A Y
Sbjct: 6345 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6404
Query: 327 EVAVKDE-----KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKD 381
V++ + K L V+E + IV PL+D + V +V+ + W K+
Sbjct: 6405 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6464
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEV 441
G E+ F R ++ D +H+L D D G Y V + AEL++ E E
Sbjct: 6465 GEEVP----FDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEF 6520
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
++ + D TV + AVF C++S EK KWY+NG E++ K+ G H+L+I D R
Sbjct: 6521 VEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCR 6580
Query: 502 PEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
+DE +Y V D + A+L EI VE + PP+ L+ G + + + N
Sbjct: 6581 LDDECEYACGVEDRKS---RARLFVEEIPVEII---RPPQDILEAPG---ADVVFLAELN 6631
Query: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
K +++V V ++GD+ +EG +I + C + D+G Y
Sbjct: 6632 KDKVEVQWLRNNMVV---VQGDKHQMMSEG--KIHRLQIC------DIKPRDQGEYRFIA 6680
Query: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL-VERKK 679
+ A L++ P +I + +D + D GKP+T + +
Sbjct: 6681 K----DKEARAKLELAAAP------KIKTADQDLVV--------DVGKPLTMVVPYDAYP 6722
Query: 680 KGSQRWMKLNFEVFT---ETTYEST--KMIE---GILYEMRVFAVNAIGVSQPSMNTKPF 731
K W K N + T +TT E T +++E G ++ N G ++ +N K
Sbjct: 6723 KAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVI 6782
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
P +L V + D +L W P G I GY+VE + WV A T+
Sbjct: 6783 DVPGPVR---NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLA-TDRA 6838
Query: 792 ERCGFTVKNLPT-GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
E C FTV L G LFRV N G EP PV R + P P ++ T
Sbjct: 6839 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITD 6896
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---FDTVFFVRQAARS-- 905
+ + G L P GGA + + +R +DT VR S
Sbjct: 6897 VNRFGVSLTWEPPEY----------DGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSAT 6946
Query: 906 -----DSGEYELSVQIEN-----MKDTATIRIRV---VEKAGPPINVMVKEVWGTNALVE 952
+ EY V+ +N AT ++V +E+ PP+N+ + ++ ++
Sbjct: 6947 VTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLK 7006
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P DG S I+GY +++ ++ W + + V+ L GN+Y +RV EN
Sbjct: 7007 WEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENK 7066
Query: 1012 CGLSD-SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
G+SD S + TA T +K+ + P +T L+
Sbjct: 7067 AGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPST------------ 7114
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
G+P+P W + + + L I D G YT + N +
Sbjct: 7115 --GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7172
Query: 1131 AECKLEV 1137
E + V
Sbjct: 7173 GEIDVNV 7179
Score = 201 bits (510), Expect = 4e-51
Identities = 147/489 (30%), Positives = 221/489 (45%), Gaps = 29/489 (5%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKR 597
PP++ LD T + I V G +R+ + G P P TW K +V EKR
Sbjct: 11600 PPEVELDV---TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR-------EKR 11649
Query: 598 VDCSSFV------IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVG 651
VD + I+ A R D G+Y I N G S + V+D P P + +++T+V
Sbjct: 11650 VDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11709
Query: 652 EDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
++ + WE P+ +GG +T ++VE +K + W + +V ++ Y
Sbjct: 11710 KENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYF 11767
Query: 712 RVFAVNAIGVSQPSMNTK-PFMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
RV A N +GV P++ TK P + I P EP +L + D T LKWR P+ G
Sbjct: 11768 RVCAENKVGVG-PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 11826
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y VE L+GS++W + ++ + V FRV N G S+ +
Sbjct: 11827 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TE 11885
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-- 885
V ++E + P + L L K G+ + L +GKP P+V WTK D +R
Sbjct: 11886 EVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 11943
Query: 886 -VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEV 944
V + T + F + +A RSD G+Y ++ A + V++K GP N+ + +V
Sbjct: 11944 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDV 12003
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
V W P+DDG EI Y ++K + K M W TV+ LI GNEY F
Sbjct: 12004 SSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIF 12063
Query: 1005 RVYTENICG 1013
RV EN G
Sbjct: 12064 RVRAENKIG 12072
Score = 200 bits (508), Expect = 7e-51
Identities = 148/582 (25%), Positives = 254/582 (43%), Gaps = 35/582 (6%)
Query: 450 VKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
VKA EQ + T W K+G ++ + R+ +S L I + ED G Y
Sbjct: 19101 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19160
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
A S++ + I LD G I V+ + ++I
Sbjct: 19161 ELCVSNSAGSITVPITI---------------IVLDRPGPPGPIRIDEVSCDS----ITI 19201
Query: 569 TGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN 622
+ PP ++ ++ + T+T + + V +S I E ++ + N
Sbjct: 19202 SWNPPEYDGGCQISNYIVEKKETTSTTWHI-VSQAVARTSIKIVRLTTGSEYQFRVCAEN 19260
Query: 623 PVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
G+ S VV P PP ++ + ++ W+ P+ DGG V GY +E
Sbjct: 19261 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19320
Query: 678 KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPT 737
K++ S W K N + +T + + + EG++YE RV+A N G+ + S + +P P
Sbjct: 19321 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19380
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
P V ++T + +LKW P+ G I GY+VE W+ N ++ F
Sbjct: 19381 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19440
Query: 798 VKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGE 856
V L R FRV N A SEP+ P+ +++ EPP++ + R + K GE
Sbjct: 19441 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19500
Query: 857 QLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L + G+P P + W K G + + +R + ++D T+ V+ R D+G+Y L+++
Sbjct: 19501 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLK 19560
Query: 916 IENMKDTATIRIRVVEKAGPPINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
+ + +V++K GPP + + + + W P++DG ++I Y V+K +
Sbjct: 19561 NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET 19620
Query: 975 KTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + TSC V+ L+ GNEY FRV N G+ +
Sbjct: 19621 SHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 19662
Score = 198 bits (504), Expect = 2e-50
Identities = 117/410 (28%), Positives = 204/410 (49%), Gaps = 22/410 (5%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTET- 696
+P PP ++ + + ++ W PP+ +GG P+TGY +E++++GS W +++ T+
Sbjct: 9293 LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9352
Query: 697 ----TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVT 749
+ +++EG+ Y+ R A+NA G+ PS + P + PI P P V+D T
Sbjct: 9353 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 9412
Query: 750 DTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP---VERCGFTVKNLPTGAR 806
++ +L W+PP + G I GY+VE EG+ +W N EP + C V NL +
Sbjct: 9413 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVN-EPDKLITTCECVVPNLKELRK 9471
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
FRV VN AG SEP+ + +I E P++ + + + K G Q+ + +G
Sbjct: 9472 YRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG 9531
Query: 867 KPRPQVVWTKGGAPLDTSR--VH-------VRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+P P+ W G + VH + T++ +V + + RS +G+Y ++ + +
Sbjct: 9532 RPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNK 9591
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ TA R++V++ GPP ++ V ++ + + W+ P DDG I GY ++K
Sbjct: 9592 AGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK 9651
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS-PGVSKNTAR 1026
W V T+ V DL+ +Y+FRV EN G+ + + TAR
Sbjct: 9652 AWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR 9701
Score = 198 bits (503), Expect = 3e-50
Identities = 169/622 (27%), Positives = 268/622 (43%), Gaps = 40/622 (6%)
Query: 430 AELIVEEKQLEVLQDIADLT-----VKASEQAVFKCEVSDE---KVTGKWYKNGVEVRPS 481
+ +I++E Q+E D+ +T KA +S KVT W + ++ +
Sbjct: 22329 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT--WKLEEMRLKET 22386
Query: 482 KRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKI 541
R++I+ L + D D G Y L +A + + V + + P
Sbjct: 22387 DRVSITTTKDRTTLTVKDSMRGDSGRYFLT-----LENTAGVKTFSVTVVVIGRPGPVTG 22441
Query: 542 HLDCSGKTSENAIVVVAGNKLRLDVSITG------EPPPVATWLKGDEVFTTTEGRTRIE 595
++ S ++E+ ++ K IT E A L V T T +
Sbjct: 22442 PIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22501
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
K ++ S F + S R V+ P+ E I P P + V +
Sbjct: 22502 KYMEYS-FRVSSENR-------FGVSKPL-ESAPIIAEHPFVPPSAPTRPEVYHVSANAM 22552
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WE P +DGG + GY VE+K++ + W+K N E Y+ T ++EG+ Y+ R +A
Sbjct: 22553 SIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYA 22612
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE- 774
+NA GVS+ S ++P M P P V DVT +T +L W P G + GY++E
Sbjct: 22613 LNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIER 22672
Query: 775 --YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSEPATLAQPVTI 831
G W+ N V FTV L G FRV+ N AG S+ + PVT
Sbjct: 22673 KPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTC 22732
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVR 889
R+ PPK L L + + G L L GKP P+++WTKG LD +V ++
Sbjct: 22733 RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQ 22792
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
+ ++ RSDSG+Y L+V+ + ++ ++V++ GP + V V
Sbjct: 22793 YTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKC 22852
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W P++DG +EI Y V++ + + W V S V+ LI NEY FRV
Sbjct: 22853 TLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22912
Query: 1010 NICG----LSDSPGVSKNTARI 1027
N G + P V++N+ I
Sbjct: 22913 NKYGPGVPVESEPIVARNSFTI 22934
Score = 197 bits (501), Expect = 5e-50
Identities = 164/594 (27%), Positives = 258/594 (43%), Gaps = 46/594 (7%)
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKL 495
L+ + DL A E + F+ ++ + GK W K + R+++ L
Sbjct: 13679 LKGLPDLCYLAKENSNFRLKIP---IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 13735
Query: 496 VIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV 555
++ D + D G YT A K + IKV V K P + T+E
Sbjct: 13736 IVYDCQKSDAGKYTITLKNVA---GTKEGTISIKV--VGKPGIPTGPIKFDEVTAEA--- 13787
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKGDEVFT-TTEGRTRIEKR-VDCSSFVIESA---QR 610
+++ PP G E+ E R + + V C+S V ++ R
Sbjct: 13788 ----------MTLKWAPPKDDG---GSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 13834
Query: 611 EDEG-RYTIKVTNP----VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPP 662
EG YT +V+ VGE + S + DVPD P I V D L W P
Sbjct: 13835 LHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDP 13894
Query: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
GG P+TGY +E K++ S W + N ++ T + EG+ YE RV A+N GV
Sbjct: 13895 KKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVG 13954
Query: 723 QPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+PS+ ++P + + P P V ++T + TL W P G + GY+VE S+
Sbjct: 13955 KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS 14014
Query: 783 WVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIR 841
W+ AN V C FTV +L G + FR+ N AG S P+ + + ++ E P I
Sbjct: 14015 WMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIV 14074
Query: 842 LPRHLRQTYIRKVGEQLNL-VVPFQGKPRPQVVWTKGGAPLDTSRV-HVRTSDFDTVFFV 899
L ++ K G+ + L + GKP P+ W+K G + S + + ++ ++ +
Sbjct: 14075 LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTI 14134
Query: 900 RQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
+ A R D+GEY ++ +++ V++ GPP V + V A + W P +D
Sbjct: 14135 KYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLED 14194
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
G S I Y ++K + + W V E + + LI GNEY FRV N G
Sbjct: 14195 GGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14248
Score = 192 bits (489), Expect = 1e-48
Identities = 116/380 (30%), Positives = 190/380 (50%), Gaps = 8/380 (2%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP A+ + V + L WEPP DGG+P+ Y++E+K++ RW+K + +
Sbjct: 7879 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7938
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T +IEG + +V A N GV PS T+ P +P S PL L V D +
Sbjct: 7939 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7998
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTV-KNLPTGARILFRVVGV 814
W+PP + G I GY VE C G+E+W+ N+ P++ F V + + + RV V
Sbjct: 7999 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 8058
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
N G SEP+ +++ V ++ P I L H I GE+L++ VPF+ P P V W
Sbjct: 8059 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 8115
Query: 875 TKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKA 933
K G + S R+ ++ V ++ R+D+G Y ++++ + TA+I ++V+
Sbjct: 8116 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 8175
Query: 934 GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTV 993
GP ++ ++ ++ + W+ P+ DG + I+ Y +++ + + V S TV
Sbjct: 8176 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 8235
Query: 994 SDLIVGNEYYFRVYTENICG 1013
DLI EY+FRV N G
Sbjct: 8236 KDLIPNGEYFFRVKAVNKVG 8255
Score = 191 bits (485), Expect = 3e-48
Identities = 127/440 (28%), Positives = 205/440 (46%), Gaps = 10/440 (2%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVPD 640
T+T T + V + + +E ++ IK N G D A + +++ P
Sbjct: 20307 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPG 20366
Query: 641 PPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYES 700
PP +T+V + + W P+ +GG V GY +E K + S W K N V T ++
Sbjct: 20367 PPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKV 20426
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPP 760
T + G++YE RV+A NA GV +PS ++P + I P ++ + D++ + +L W+ P
Sbjct: 20427 TTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQP 20486
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR- 819
G I GY+VE W A+ V F + L ++ FRV N G
Sbjct: 20487 AFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSI 20546
Query: 820 SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA 879
S P+ + P+T + P I LP + + G + L GKP P + W K
Sbjct: 20547 SNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDK 20606
Query: 880 PLDTSRVHV--RTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPI 937
L T+ + T+D ++ ++ A R +SG YEL ++ +ATIR+++++K GPP
Sbjct: 20607 ELQTNALVCVENTTDLASI-LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPG 20665
Query: 938 N-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ K V + W+ P DDG ++I Y V+K + + W V E T + +
Sbjct: 20666 GPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI 20725
Query: 997 IVGNEYYFRVYTENICGLSD 1016
I GNEY FRV N G+ +
Sbjct: 20726 IKGNEYIFRVRAVNKYGIGE 20745
Score = 189 bits (480), Expect = 1e-47
Identities = 117/378 (30%), Positives = 174/378 (46%), Gaps = 7/378 (1%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PD P+ + V + ++ W P D G P+ GY +E+++ S W ++N +
Sbjct: 8598 PDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKA 8656
Query: 699 ESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTL 755
++EG+ Y RV A NA G S PS PI+P P+ + D + TT L
Sbjct: 8657 NVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVT-DTSSTTIEL 8715
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W PP G G I GY V+ L G+ EW + ++ +TVK + GA RV VN
Sbjct: 8716 EWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVN 8775
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
AG P QPVT+ E EPP + L ++ G+ L + G+P P VWT
Sbjct: 8776 AAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWT 8834
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K LD RV + + ++ A R D G Y ++ A R+ V + GP
Sbjct: 8835 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGP 8894
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+++ L+ W P+DDG SEI G+ +++ D K W E R + C ++
Sbjct: 8895 VLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER-SKCDITG 8953
Query: 996 LIVGNEYYFRVYTENICG 1013
L+ G EY FRV +N G
Sbjct: 8954 LLEGQEYKFRVIAKNKFG 8971
Score = 171 bits (432), Expect = 5e-42
Identities = 168/618 (27%), Positives = 263/618 (42%), Gaps = 61/618 (9%)
Query: 429 EAELIVEEKQLEVLQDI---ADLTVKASEQAVFKCEVS---DEKVTGKWYKNGVEVRPSK 482
E + + ++ E+ D+ A LTVKA + V+ + K+T W K + ++ K
Sbjct: 7373 EIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDK 7430
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
RITI +V + + I D + D G Y A+++ + + ++V + K PP
Sbjct: 7431 RITIENVPKKSTVTIVDSKRSDTGTYII----EAVNVCGRATAV-VEVNVLDKPGPPAA- 7484
Query: 543 LDCSGKTSENAIVV------VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
D + T+E+ ++ G+K+ + + W K T + + K
Sbjct: 7485 FDITDVTNESCLLTWNPPRDDGGSKI-TNYVVERRATDSEVWHKLSS--TVKDTNFKATK 7541
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ A G V PV + Q D P PP + + + +D
Sbjct: 7542 LIPNKEYIFRVAAENMYG-----VGEPVQASPITAKYQ-FDPPGPPTRLEPSDITKDAVT 7595
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W P DGG P+TGY VER + +W++ N +TTY + Y RV A
Sbjct: 7596 LTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAE 7655
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G +PS +T+P + PI P P V+DV T+ L W P G I+ Y++
Sbjct: 7656 NLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVI 7715
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E G++EWV E V + L G FRV VN AG SEP+ + PV RE
Sbjct: 7716 EMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCRE 7774
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKP------RPQVVWTKGGAPLDT-- 883
PP PR L I K L VP + G P + V KG +DT
Sbjct: 7775 KLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTV 7832
Query: 884 --SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRVVEKAGPPIN 938
++ V +++ R AA + G+ + + +IE+ KDT T GPP
Sbjct: 7833 KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYT-EIEDSVLAKDTFT-------TPGPPYA 7884
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT--VSDL 996
+ V +V + ++W+ PK+DG I Y ++K ++ W + C V+D+
Sbjct: 7885 LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKA-GKTAGPDCNFRVTDV 7943
Query: 997 IVGNEYYFRVYTENICGL 1014
I G E F+V EN G+
Sbjct: 7944 IEGTEVQFQVRAENEAGV 7961
Score = 169 bits (427), Expect = 2e-41
Identities = 134/515 (26%), Positives = 221/515 (42%), Gaps = 40/515 (7%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
+ +++ D+T K E A C++ + KWY+ G E+ S++ +S GR H L +
Sbjct: 24230 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24289
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
EDEG YT + + L Q P+ H G + G
Sbjct: 24290 EEQEDEGVYTCIATNEVGEVETSSKLL--------LQATPQFH---PGYPLKEKYYGAVG 24338
Query: 560 NKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE-GRYTI 618
+ LRL V G P P TW G ++ +E T IE + V+++ QR+ G+Y +
Sbjct: 24339 STLRLHVMYIGRPVPAMTWFHGQKLLQNSENIT-IENTEHYTHLVMKNVQRKTHAGKYKV 24397
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
+++N G A + +++ D PD P + I ++ ++ A++ W+PP DGG +T Y+VE+
Sbjct: 24398 QLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 24457
Query: 678 -KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP----------SM 726
+ K W ++ + + TT + E Y RV A N G+S P S
Sbjct: 24458 CEAKEGAEWQLVSSAI-SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24516
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
KP P PT + VT + + W+PP G I Y +E + +W+
Sbjct: 24517 FEKPGAPGKPT-------ITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISV 24569
Query: 787 NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHL 846
TE + F+VKNL G FRV N+ G SE + +++P+T + L
Sbjct: 24570 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 24629
Query: 847 RQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF---FVRQAA 903
R +R LV G P+P V W + G + + R +F + +
Sbjct: 24630 RNLNVR-YQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVT 24688
Query: 904 RSDSGEYELSV--QIENMKDTATIRIRVVEKAGPP 936
D+ Y++ Q ++ TA++ + V K P
Sbjct: 24689 DDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP 24723
Score = 156 bits (395), Expect = 9e-38
Identities = 95/314 (30%), Positives = 153/314 (48%), Gaps = 13/314 (4%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V + + PP+I L + K+ + V AG + LD ++ G+P P +W K + E
Sbjct: 12979 VTILAENVPPRIDLSVAMKS---LLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE 13035
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
G +R C + + S R+D G YTI N G A+I L+V+D P PP +V+I
Sbjct: 13036 GIKMAMQRNLC-TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINK 13094
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ D A+L WEPP+ DGG +T Y+V++++ W +++ V T+ K+IEG Y
Sbjct: 13095 MYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEY 13153
Query: 710 EMRVFAVNAIGV-----SQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
+ R+ A N GV ++P++ P+ P P ++ ++T T+ W+PP G
Sbjct: 13154 QFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP---VISNITKDHMTVSWKPPADDG 13210
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I GYL+E + W N +P+ L G FRV +N AG +P+
Sbjct: 13211 GSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13270
Query: 825 LAQPVTIREIAEPP 838
++ R+ PP
Sbjct: 13271 ASKAAYARDPQYPP 13284
Score = 154 bits (388), Expect = 6e-37
Identities = 221/934 (23%), Positives = 348/934 (37%), Gaps = 146/934 (15%)
Query: 271 GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV 330
G + + E++ + ++W +N + K+ + GK L I D Y
Sbjct: 6621 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 6680
Query: 331 KDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSE-EGAQVMWMKDGVELTRE- 388
KD++ +L + P I T +D V VG + M V A+ W K+ L+ +
Sbjct: 6681 KDKEARAKLELAAAPK-IKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT 6739
Query: 389 -DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
D+ + F+ + + D+GRY+++ +AE + K ++V + +
Sbjct: 6740 IDTTAEQTSFR---------ILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRN 6790
Query: 448 LTVKASEQAVFKCEVS---DEKVT---GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
L V + F EVS +E +T K VE R KR T ++ D
Sbjct: 6791 LEVTET----FDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTW--------VLATDRA 6838
Query: 502 PEDEGDYTFVPDG---YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA 558
E T + G Y +SA+ + + D G I V
Sbjct: 6839 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN 6898
Query: 559 GNKLRLDVSITGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
R VS+T EPP + ++ T+ T + R + S +
Sbjct: 6899 ----RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQ 6954
Query: 613 EGRYTIKVTNPVG---EDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDG 666
E + ++ N +G A+ F++V D P PP + + + L WEPP+ DG
Sbjct: 6955 EYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDG 7014
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSM 726
G P+ GY++ER ++G W++ N ++ E TY+ T + +G Y RV A N GVS PS
Sbjct: 7015 GSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 7074
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
P EP D++ L+ PN I VP+
Sbjct: 7075 ILGPLTADDAFVEP----TMDLSAFKDGLEVIVPNPITI-----------------LVPS 7113
Query: 787 N--TEPVERCGFTVKNLPTGARILFRVVG------VNIAGRSEPA-----------TLAQ 827
P F K L TG R+ + + ++ + RS+ T++
Sbjct: 7114 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7173
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD----- 882
+ + IA P P+ L+ I K L P GG+PL
Sbjct: 7174 EIDVNVIARPSA---PKELKFGDITKDSVHLTWEPPDDD----------GGSPLTGYVVE 7220
Query: 883 ----TSRVHVRTSDFDT-------------VFFVRQAARSDSGEYELSVQIE--NMKDTA 923
+ + + DF T + + AR+ G E + E NM A
Sbjct: 7221 KREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPA 7280
Query: 924 TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
T+ PP NV ++ + + W PK+DG S I GY V++ + + +W
Sbjct: 7281 TV-------PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 7333
Query: 984 ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
E T V+ L G Y +RV N G S S+ T I P +
Sbjct: 7334 EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRPTEEIQAVDTQEAP------E 7384
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+ K L L V AG L V G P+PK+ W K M +++D + I N
Sbjct: 7385 IFLDVKLLAGL---TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7441
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
T+ I D GTY AVN G A A ++ V
Sbjct: 7442 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 152 bits (385), Expect = 1e-36
Identities = 103/305 (33%), Positives = 150/305 (49%), Gaps = 8/305 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
E P I LD T ++ + + AG+ + L+ +SI G+P P ++W K + ++ T+I
Sbjct: 14069 EAPTIVLD---PTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSD-ITQIT 14124
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S I+ A R+D G YTI TNP G V + + V+DVP PP V I++V + A
Sbjct: 14125 STPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKA 14184
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L W PP+ DGG P+ Y++E+++ W ++ E + +TK+I+G Y RV A
Sbjct: 14185 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQGNEYIFRVSA 14243
Query: 716 VNAIGVSQP--SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
VN G +P S K P P V +VT T T+ W+ P G I GY V
Sbjct: 14244 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14303
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E + S WV A PV V L G+ FRV N AG P+ + V +++
Sbjct: 14304 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14363
Query: 834 IAEPP 838
A PP
Sbjct: 14364 AAYPP 14368
Score = 150 bits (378), Expect = 9e-36
Identities = 188/818 (22%), Positives = 320/818 (39%), Gaps = 114/818 (13%)
Query: 277 MVEISDPDLTLKWFK----NGQEI-------KPSSKYVFENVGKKRI----LTINKCTLA 321
++ IS +TL+W K G+EI + S ++ K+RI TI A
Sbjct: 24134 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24193
Query: 322 DDAAYEVAVKDEKCF-----------TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-V 369
+ + V ++E T+L E P I ++D +G+ +++ + V
Sbjct: 24194 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKEMKDVTTKLGEAAQLSCQIV 24252
Query: 370 SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCE 429
+ W + G EL + +Y+ DG+ H L QED G Y I E
Sbjct: 24253 GRPLPDIKWYRFGKELIQS----RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24308
Query: 430 AE-----LIVEEKQLEVLQDIADLTVKA--SEQAVFKCEVSDEKVTGKWYKNGVEVRPSK 482
E L+ Q + + A S + + W+ ++ S+
Sbjct: 24309 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24368
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
ITI + + LV+ +V+ + Y + LS ++ ++ + +P K
Sbjct: 24369 NITIENTEHYTHLVMKNVQRKTHAGK------YKVQLSNVFGTVDAILDVEIQDKPDK-- 24420
Query: 543 LDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKGDEVFTTTEGRTRIEKRVDC 600
IV+ A L+ I+ +PP +W+ + V E + E ++
Sbjct: 24421 -------PTGPIVIEA--LLKNSAVISWKPPADDGGSWIT-NYVVEKCEAKEGAEWQLVS 24470
Query: 601 SSFVIESAQ----REDEGRY-------TIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
S+ + + + E+ G Y T +++P+ I + P P IT+
Sbjct: 24471 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 24530
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
V +D ++ W+PP DGG + Y +E+++K +W+ + E ET + +IEG+ Y
Sbjct: 24531 VTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEY 24590
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPT--------SEPLHLIVEDVTDTTTTLK----- 756
E RV N G S+ S ++P P + E +L V ++ T K
Sbjct: 24591 EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHP 24650
Query: 757 ------WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
+R I A G+ Y ++ G + + A+ + + V+ G +
Sbjct: 24651 KPIVKWYRQGKEIIADGLK-YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSV--- 24706
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV--GEQLNLVVPFQGKP 868
S A+L E+ P KI LP+ L GE +++ +PF GKP
Sbjct: 24707 ---------SGTASL-------EVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 24750
Query: 869 RPQVVWTKGGAPLDTSRVH--VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
P + W KG +D + + + T F ++ F R D+G Y + + D T+
Sbjct: 24751 DPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE 24810
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
+ V + PP V V +V + + W P DG S+I Y V+K W V +
Sbjct: 24811 LDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA- 24869
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNT 1024
R T TV +L Y FRV EN GLS S+ T
Sbjct: 24870 RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 24907
Score = 149 bits (375), Expect = 2e-35
Identities = 110/360 (30%), Positives = 159/360 (44%), Gaps = 37/360 (10%)
Query: 268 VDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYE 327
V G E+S D+ ++W+ G++++PS K V + GK LT+ L D +
Sbjct: 5902 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5961
Query: 328 VAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTR 387
+ KD K LFVKEPPV PLEDQ V G + EVS E A+V W K+G E+ +
Sbjct: 5962 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 6021
Query: 388 EDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
+Y DG+ L+ D ED Y + L V +E L+ + D
Sbjct: 6022 ----SKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTD 6077
Query: 448 LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGD 507
L V+ E A F+CE+S E KW+K+G E++ K+ I G LVI+ +DE +
Sbjct: 6078 LQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAE 6137
Query: 508 YTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVS 567
Y+ + S L LE + + + + SE + KL +VS
Sbjct: 6138 YSC--EVRTARTSGMLTVLEEEAVFTKNL--------ANIEVSETDTI-----KLVCEVS 6182
Query: 568 ITGEPPPVATWLKGDEVF-------TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
+P W KGDE TEGR RI VI++A ED G Y ++
Sbjct: 6183 ---KPGAEVIWYKGDEEIIETGRYEILTEGRKRI--------LVIQNAHLEDAGNYNCRL 6231
Score = 149 bits (375), Expect = 2e-35
Identities = 101/318 (31%), Positives = 146/318 (45%), Gaps = 14/318 (4%)
Query: 528 IKVEYVPKQEP---PKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKG-DE 583
+K E V +E P + L SG + V AG+ +RL+ + G+P P W K D
Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSG-----VLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDA 11936
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
T R +I+ R D S F + A+R D G+Y + TN G VA + V+D P P
Sbjct: 11937 TDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVR 11996
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++I V D + W+PP DGG + Y++E+ + W + V T T T++
Sbjct: 11997 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT-TVTRL 12055
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT---TTLKWRPP 760
IEG Y RV A N IG P+ +KP + +P +VT + T+ W PP
Sbjct: 12056 IEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPP 12114
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS 820
G I GY +E + S WVP N + V+NL FRV N G
Sbjct: 12115 EYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIG 12174
Query: 821 EPATLAQPVTIREIAEPP 838
EP+ ++PV ++ EPP
Sbjct: 12175 EPSLPSRPVVAKDPIEPP 12192
Score = 145 bits (366), Expect = 2e-34
Identities = 135/522 (25%), Positives = 214/522 (40%), Gaps = 46/522 (8%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP + VG+ L W P +DGG + Y++E K G+ W+++ V T
Sbjct: 7676 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPT- 7734
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTT 752
T + ++EG Y RV AVN G S+PS + P + + P S P L V ++T T
Sbjct: 7735 TQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7794
Query: 753 TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVV 812
LKW P + G I Y+VE + W +T V+ TV L G+ +FRV
Sbjct: 7795 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVA 7853
Query: 813 GVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKPRP 870
N G+S+ + V ++ P P L + K L P G+P
Sbjct: 7854 AENAIGQSDYTEIEDSVLAKDTFTTPGP--PYALAVVDVTKRHVDLKWEPPKNDGGRPIQ 7911
Query: 871 QVV----------WTKGG---APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ V W K G P RV + F VR + G +I
Sbjct: 7912 RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 7971
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+++D + PP+++ V + + + W+ P+ +G S I+GY V+ T
Sbjct: 7972 SIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTE 8024
Query: 978 EWFNVYERN-RHTSCTVSDLIVGN-EYYFRVYTENICGLSDSPGVSKNTARILKTGITFK 1035
+W V R + V + +V + EY RV N G+S+ +S+N + K
Sbjct: 8025 KWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV--VAKDPDCKP 8082
Query: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
+ + HD +V+ G ++ R P P V W K+ E++ +
Sbjct: 8083 TIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8129
Query: 1096 ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N L + + DAG YT N+LG A A ++V
Sbjct: 8130 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 137 bits (345), Expect = 6e-32
Identities = 141/569 (24%), Positives = 234/569 (41%), Gaps = 50/569 (8%)
Query: 68 DAVVVAKVNGKELPDKPTIKWFKGKWL----ELGSKSG--ARFSFKESHNSASNVY---T 118
+ V A+V GK+ + + + K++ + K G A F + SH V+
Sbjct: 5246 EGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKND 5305
Query: 119 VELHIGKVVL--GDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKS 176
+LH + VL + ++LE+K D V+ A + LE+ + K
Sbjct: 5306 AKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLH 5365
Query: 177 D-TAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGI 235
D TA E D L K EV ++ K KD +++ P+ G ++ K A
Sbjct: 5366 DKTAVEKDEITL--KCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKA----- 5418
Query: 236 TDLRGMLKRL-----KKAKVEVKKSAAFTKKLDPAYQVDR--GNKIKLMVEISDPDLTLK 288
DL+ + + K K V A K P Y V+ G +E+S+PD+ +
Sbjct: 5419 -DLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ 5477
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLI 348
W GQ + S GKK IL ++ C L + K L VKE P++
Sbjct: 5478 WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIF 5537
Query: 349 VTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIF 408
+TPL D +VF D + EVS E W+K E+T +D R+ KDG +H ++
Sbjct: 5538 ITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDD----RFELIKDGTKHSMVI 5593
Query: 409 SDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVT 468
ED +Y +LI+E +L+ L + D+T K E AVF E+S + +
Sbjct: 5594 KSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIR 5653
Query: 469 GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEI 528
KW+KN + ++ +++ G+ H + D+ +D + +S AKL LE
Sbjct: 5654 VKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRV--EAMGMSSEAKLTVLEG 5711
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+ K + D +G + I L I+ PV + G E+ +
Sbjct: 5712 DPYFTGKLQ------DYTGVEKDEVI---------LQCEISKADAPVKWFKDGKEIKPSK 5756
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYT 617
+ + + +++ A + D G+YT
Sbjct: 5757 NAVIKADGKK--RMLILKKALKSDIGQYT 5783
Score = 136 bits (342), Expect = 1e-31
Identities = 97/354 (27%), Positives = 155/354 (43%), Gaps = 30/354 (8%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ IVV AG L+ I G+P P W K + T R I+ + ++ V++ R
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKP 669
D G+Y +K++N G I ++V+D P PPE +++T V + L W PP+ DGG
Sbjct: 18469 TDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGAN 18528
Query: 670 VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMN-- 727
++ Y++E+++ W +++ EV Y+ TK++ G Y RV AVN G+ +P +
Sbjct: 18529 ISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGP 18587
Query: 728 ---TKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
P+ P P S P V +T + + W P G I+GY++E + W
Sbjct: 18588 VTACNPYKPPGPPSTPE---VSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18644
Query: 785 PANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N + + V L G FRV N AG EP+ + + PP
Sbjct: 18645 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP------ 18698
Query: 845 HLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVRTSDFD 894
G N V + + W+K GGAP+ V V+ + D
Sbjct: 18699 ----------GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 18742
Score = 134 bits (338), Expect = 4e-31
Identities = 118/428 (27%), Positives = 186/428 (43%), Gaps = 39/428 (9%)
Query: 430 AELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKW----YKNGVEV-RPSKRI 484
+E +V + + V + DL VK EV+ VT W Y G E+
Sbjct: 10400 SEALVIREPITVPERPEDLEVK---------EVTKNTVTLTWNPPKYDGGSEIINYVLES 10450
Query: 485 TISHVGRFHKLVIDD-------VRPEDEGD-YTFVPDGYALSLSAKLNFLEIKVEYVPKQ 536
+ +FHK+ D+ V+ EGD Y + + K +F + +
Sbjct: 10451 RLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDEL 10510
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
PP +HLD K + + G L +G+P P +W K DE + RT I+
Sbjct: 10511 APPTLHLDFRDK-----LTIRVGEAFALTGRYSGKPKPKVSWFK-DEADVLEDDRTHIKT 10564
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWA 655
+ A+R D G+Y + V N G + VVD P PP V V +D+
Sbjct: 10565 TPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM 10624
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
++ W+PP+ DGG +T Y++E+K+ G WM + +TT + +K++EG Y R+ A
Sbjct: 10625 VISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT-SASAKTTCKVSKLLEGKDYIFRIHA 10683
Query: 716 VNAIGVSQP----SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
N G+S P SM K + P IV +VT + + W P+ G I Y
Sbjct: 10684 ENLYGISDPLVSDSMKAKDRFRV--PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNY 10740
Query: 772 LVEYCLEGSEEWVPANTEPVE-RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
++E S+ W +P+ F V +L G + FRV N G +P+ ++PV
Sbjct: 10741 ILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVF 10800
Query: 831 IRE-IAEP 837
++ IA+P
Sbjct: 10801 AKDPIAKP 10808
Score = 130 bits (326), Expect = 9e-30
Identities = 119/457 (26%), Positives = 183/457 (40%), Gaps = 38/457 (8%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K G ++ SKR I+ +LVI + D G Y V + K +++++
Sbjct: 23864 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN---KCGKKAVYIKVR 23918
Query: 530 VEYVPKQEPPKIHLDC----SGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
V P + D S + S G + L + P A W
Sbjct: 23919 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI-LGYILERREVPKAAWYT----- 23972
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN------PVGEDVASIFLQVVDVP 639
I+ RV +S V++ + E + + N P+ + ++ P
Sbjct: 23973 --------IDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP 24024
Query: 640 DPPE-AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
+PP + V + L W P DGG VTGY +ERK+ + +W++ N T T Y
Sbjct: 24025 EPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 24084
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T ++ Y+ R+ A N +G+S+ S ++P + P S+P L + ++ + TL
Sbjct: 24085 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTL 24144
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W P G I GY VEY G W +N E ++ FT+ L FRV N
Sbjct: 24145 QWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAEN 24204
Query: 816 IAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
G S P A + T E P IR + K+GE L G+P P + W
Sbjct: 24205 ETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTKLGEAAQLSCQIVGRPLPDIKW 24261
Query: 875 TKGGAPLDTSRVHVRTSDFDT-VFFVRQAARSDSGEY 910
+ G L SR + +SD T V + D G Y
Sbjct: 24262 YRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24298
Score = 126 bits (316), Expect = 1e-28
Identities = 97/360 (26%), Positives = 157/360 (43%), Gaps = 24/360 (6%)
Query: 258 FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINK 317
FT KL V++ +++ L EIS D +KWFK+G+EIKPS V + GKKR+L + K
Sbjct: 5715 FTGKLQDYTGVEK-DEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKK 5773
Query: 318 CTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM 377
+D Y +K +L +++ + +V PL +V + E+SE+
Sbjct: 5774 ALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHAN 5833
Query: 378 WMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
W G L + + K++GK H L+ + + G + A L V+ +
Sbjct: 5834 WKLKGEALLQTPDCE----IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPR 5889
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVI 497
+ +L+ + D+TV A E A F CE+S E + +WY G ++ PS ++ G+ H L +
Sbjct: 5890 VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTL 5949
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
DV+ ED G+ + A L E VE+ E + E A V
Sbjct: 5950 RDVKLEDAGEVQLTAKDF--KTHANLFVKEPPVEFTKPLEDQTV--------EEGATAV- 5998
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
L+ ++ E V + G E+ + + + RV VI ED YT
Sbjct: 5999 ------LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRV--RKLVIHDCTPEDIKTYT 6050
Score = 126 bits (316), Expect = 1e-28
Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 33/335 (9%)
Query: 526 LEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
L + V + PP I L S + + I V AG + + +TG P P W K + V
Sbjct: 9077 LPLNVVIQDDEVPPTIKLRLSVRG--DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVI 9134
Query: 586 T--------TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVD 637
T E +R E + + S I A RED+G YT+ +N +G ++ ++V D
Sbjct: 9135 EKPTDALQITKEEVSRSEAKTELS---IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYD 9191
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
P PP + +T + + L W+ P+ +GG +T Y+++++ + K +E T T
Sbjct: 9192 RPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRK---KAEWEEVTNTA 9248
Query: 698 YEST----KMIEGILYEMRVFAVNAIGVSQPSMNTK-----PFMPIAPTSEPLHLIVEDV 748
E K+I YE RV AVN G+S + K P+ P +P L
Sbjct: 9249 VEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---R 9305
Query: 749 TDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-----FTVKNLPT 803
T + + W PP G I GY +E EGS W + P+ + G F V L
Sbjct: 9306 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9365
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
G + FR + +N AG P+ + P + PP
Sbjct: 9366 GVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPP 9400
Score = 125 bits (313), Expect = 3e-28
Identities = 224/1082 (20%), Positives = 389/1082 (35%), Gaps = 140/1082 (12%)
Query: 90 KGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGF 149
KG+WL + G + S S+ + L I L D G Y +V T
Sbjct: 2603 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKT----SA 2654
Query: 150 NIDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSGL-----LKKREVVEEEKKKKKKD 204
+ VEA + ++L++ T + + EL + +K V+E +K
Sbjct: 2655 KLKVEAVKIK---KTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYA--- 2708
Query: 205 DDDLGIPPEIWEL-LKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLD 263
+ + I+ L +K + F+ G G RL V++ K L+
Sbjct: 2709 ---ISVKGTIYSLRIKNCAIVDESVYGFRLGRL---GASARLHVETVKIIKKPKDVTALE 2762
Query: 264 PAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADD 323
A + V +S + +KWF EIKPS K+ + K L + + +D
Sbjct: 2763 NA-------TVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDA 2815
Query: 324 AAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGV 383
Y V +C +LFV+ + I +++ +V EVS MW+K+GV
Sbjct: 2816 GEYTAVVGQLECKAKLFVET--LHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGV 2873
Query: 384 ELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQ 443
E+ + FK + GK H LI + ED Y + Q A L V + +
Sbjct: 2874 EIEMSEKFKIVVQ----GKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP--IMITS 2927
Query: 444 DIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPE 503
+ D+ + + F+ V+ E ++ KW KNGVE++ + + + H L I +V
Sbjct: 2928 MLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFG 2987
Query: 504 DEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLR 563
D DYTFV G A S + L ++ ++ ++ K I V+ +
Sbjct: 2988 DAADYTFVA-GKATSTAT----LYVEARHIEFRKHIK------------DIKVLEKKRAM 3030
Query: 564 LDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP 623
+ ++ EP W+K D+ T+ R +I+K +I S + D G+YT+
Sbjct: 3031 FECEVS-EPDITVQWMKDDQELQITD-RIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGN 3088
Query: 624 VGEDVASIFLQ-----------VVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTG 672
V A +F++ V V + AV V ED W Y G +
Sbjct: 3089 VS--TAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHW----YKDGIEINF 3142
Query: 673 YLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM 732
+ ER K +R + F +ET + R + +P +
Sbjct: 3143 QVQERHKYVVERRIHRMF--ISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQ 3200
Query: 733 PIAPTS-EPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
P+ S +P + W ++ + G+ ++ +G E +
Sbjct: 3201 PVTVQSGKPARFCAVISGRPQPKISWYKEEQLLS---TGFKCKFLHDGQEYTL------- 3250
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
++ P A + + + A+L+ E P++ P Y
Sbjct: 3251 ----LLIEAFPEDAAVYTCEAKNDYGVATTSASLS--------VEVPEVVSPDQEMPVYP 3298
Query: 852 RKVGEQLNLVVPFQGKPRP----------QVVWTKGGAPLDTSRVHVRTSDFDTVFF-VR 900
+ L V +G+P +V W + SR T DT +
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIA 3358
Query: 901 QAARSDSGEYEL--SVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKD 958
+A D G Y S + + TA + + V V+E + A+ + K+
Sbjct: 3359 EAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKE 3418
Query: 959 DGN---SEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
+ EI + + + + +V + + HT+ +V D + +T ++ ++
Sbjct: 3419 ESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQL-------CHTASLSQIA 3471
Query: 1016 DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHP 1075
+S +SK A+ TG APK L D V G +A C ++
Sbjct: 3472 ESTELSKECAKE-STG--------------EAPKIFLHLQDVTVKCGDTAQFLCVLKDDS 3516
Query: 1076 KPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
V W +I E + + + L I D G Y+C N+ GE L
Sbjct: 3517 FIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVL 3576
Query: 1136 EV 1137
V
Sbjct: 3577 SV 3578
Score = 124 bits (310), Expect = 7e-28
Identities = 96/374 (25%), Positives = 160/374 (42%), Gaps = 24/374 (6%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
QV + E+S + +KWFK+G EIK KY + G RIL INKC L D+A Y
Sbjct: 6079 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6138
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
V+ + L V E + L + +V D +++ EVS+ GA+V+W K E+
Sbjct: 6139 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6198
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
RY +G++ IL+ + ED G Y + + ++ V E E +
Sbjct: 6199 E----TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQ 6254
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+L + E+A F C +S E +W ++ + + + G+ LV+ D +D G
Sbjct: 6255 NLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMG 6314
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y + A +A L +E VP ++ + E VV +V
Sbjct: 6315 TYVVMVG--AARAAAHLTVIEKLRIVVPLKDT---------RVKEQQEVV-----FNCEV 6358
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
+ G A W + +E + ++K + + I A +D+ Y + +TN GE
Sbjct: 6359 NTEGAK---AKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQANYNVSLTNHRGE 6414
Query: 627 DVASIFLQVVDVPD 640
+V S +V+ D
Sbjct: 6415 NVKSAANLIVEEED 6428
Score = 123 bits (309), Expect = 9e-28
Identities = 99/374 (26%), Positives = 159/374 (42%), Gaps = 25/374 (6%)
Query: 250 VEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGK 309
V+ K+ FT++L ++ E S+P + +KW+K+G E+ KY + K
Sbjct: 2122 VQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRK 2181
Query: 310 KRILTINKCTLADDAAYE-VAVKDE--KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366
L+I +D Y V V+DE K +L V+ V V L+D +V E+
Sbjct: 2182 VHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELE 2241
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
VS E + W + VEL +Y R L DV +ED+G Y + +G
Sbjct: 2242 CIVSPENIEGKWYHNDVELKSN----GKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2297
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
+ +L ++ + + +LQ ++D V + + +VS E V G W K+G EV+PS R+ I
Sbjct: 2298 KTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI 2357
Query: 487 SHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCS 546
+ H L+I+D+ ED G+Y+F LS S +++ + V
Sbjct: 2358 VIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV---------------- 2401
Query: 547 GKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIE 606
T + V+ G K L+ ++ W DE + I K VI
Sbjct: 2402 -ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK-QRLVIN 2459
Query: 607 SAQREDEGRYTIKV 620
DEG Y + V
Sbjct: 2460 RTHASDEGPYKLIV 2473
Score = 121 bits (303), Expect = 4e-27
Identities = 99/330 (30%), Positives = 138/330 (41%), Gaps = 46/330 (13%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR------------------- 593
++ V G+++ LD SI+G P P TW+K + V E + R
Sbjct: 8383 SLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFV 8442
Query: 594 --IEKRVDC-------SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP-- 642
+ +R+ S + + R D G Y IKV N G A + V+D P PP
Sbjct: 8443 LPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN 8502
Query: 643 ---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER--KKKGSQRWMKLNFEVFTETT 697
E +R TSV + WEPP+ DGG + Y +E+ K K W+ +
Sbjct: 8503 FVFEDIRKTSV-----LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCK 8556
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTT 754
Y TK+IEG Y RV A N G P + +KP + P P P IVEDVT +
Sbjct: 8557 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8615
Query: 755 LKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGV 814
+KW P G+ I GY +E S W N + V L G +FRV
Sbjct: 8616 VKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAE 8674
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N AG + + + P T + PP +PR
Sbjct: 8675 NAAGPGKFSPPSDPKTAHDPISPPGPPIPR 8704
Score = 120 bits (302), Expect = 6e-27
Identities = 88/295 (29%), Positives = 136/295 (46%), Gaps = 15/295 (5%)
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
AG ++L I+G+P P W K D+ T +E D +S +I+ A R + G Y
Sbjct: 20581 AGTSVKLRAGISGKPAPTIEWYKDDKELQTN-ALVCVENTTDLASILIKDADRLNSGCYE 20639
Query: 618 IKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
+K+ N +G A+I +Q++D P PP + +V + L+W PP DGG +T Y+VE
Sbjct: 20640 LKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE 20699
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP-----SMNTKPF 731
+++ W ++ E E +TK+I+G Y RV AVN G+ +P + F
Sbjct: 20700 KRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAF 20758
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
+ P P V +T + T+ W P G I GY +E + S W E +
Sbjct: 20759 VTPGPPGIP---EVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 20815
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGR---SEPATLAQPVTIREIAEPP-KIRL 842
V L + +RV VN AG+ SEP+ + + PP KIR+
Sbjct: 20816 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRI 20870
Score = 120 bits (300), Expect = 1e-26
Identities = 87/326 (26%), Positives = 140/326 (42%), Gaps = 29/326 (8%)
Query: 523 LNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGD 582
L+ + K +VP P ++ + +G+ A AG+KLR +T
Sbjct: 23435 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT------------- 23481
Query: 583 EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+E + I D G YT+++ N G +I + ++D P PP
Sbjct: 23482 -----------VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPP 23530
Query: 643 EA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
++I + + WEPP DGG P++GY+VE++ W+ ++ E T +T++ T
Sbjct: 23531 TGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVS-ESVTRSTFKFT 23589
Query: 702 KMIEGILYEMRVFAVNAIGVSQ--PSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
++ EG Y RV A N G+ S + I P L + DV+ TL W P
Sbjct: 23590 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23649
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G + GY+VE ++ WV N PV + L G RV +N G
Sbjct: 23650 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23709
Query: 820 SEPATLAQPVTIRE-IAEPPKIRLPR 844
+P+ ++P+ + IA P K + PR
Sbjct: 23710 GKPSRPSKPIVAMDPIAPPGKPQNPR 23735
Score = 117 bits (294), Expect = 5e-26
Identities = 129/529 (24%), Positives = 197/529 (37%), Gaps = 82/529 (15%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
V +P PP +I G+ + W P++DGG P+TGY VE KK W K + +
Sbjct: 19776 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRG 19834
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLH---------LIVE 746
T Y + + G Y RV +VN +G S PS ++ P + EPL LIV+
Sbjct: 19835 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19894
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+ +R G V L W +T+ R + T
Sbjct: 19895 AGASFTMTVPFR-----------GRPVPNVL-----WSKPDTDLRTRAYVDTTDSRTSLT 19938
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
I A R++ +TI+ + + L + T G N+ V
Sbjct: 19939 I-------ENANRNDSGKYT--LTIQNVLSAASLTLVVKVLDT----PGPPTNITVQDVT 19985
Query: 867 KPRPQVVW----TKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
K + W GGAP+ + R + V LS ++ N+++
Sbjct: 19986 KESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCN------RLSYKVTNLQEG 20039
Query: 923 ATIRIRV--------------------VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
A RV EK PP + V + + + W P+ DG S
Sbjct: 20040 AIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGS 20099
Query: 963 EIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
I+ Y V+ +K W + T VS L +EY+FRV+ EN GLSD
Sbjct: 20100 RIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEYFFRVFAENQAGLSDP----- 20153
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+L + + E E D + P V AG + ++ + G P PKV
Sbjct: 20154 --RELLLPVLIKEQLEPPEIDMKNFPSHTV-----YVRAGSNLKVDIPISGKPLPKVTLS 20206
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALA 1131
++ + ++ +F LT+N++ DAG Y A N G A
Sbjct: 20207 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 20255
Score = 117 bits (293), Expect = 6e-26
Identities = 130/526 (24%), Positives = 205/526 (38%), Gaps = 68/526 (12%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF--EVFTET 696
P PEA+ T D L W+PP +DGG + GY+VE +K G + W + N E ET
Sbjct: 10811 PVNPEAIDTTCNSVD---LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 10867
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLK 756
Y+ T + +G Y+ RV AVNA G S P+ +P + + EP LI++ +K
Sbjct: 10868 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIK 10926
Query: 757 WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR------ 810
R+ A +++ W + + + V P G+++ R
Sbjct: 10927 VGDTLRLSA------IIKGVPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHED 10978
Query: 811 --VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF---- 864
+ + + + T++ V + + PP R L + IRK L P
Sbjct: 10979 GGIYSLTVENPAGSKTVSVKVLVLDKPGPP-----RDLEVSEIRKDSCYLTWKEPLDDGG 11033
Query: 865 --------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI 916
+ + W+ A + + + R AA + G +
Sbjct: 11034 SVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPF---V 11090
Query: 917 ENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKT 976
E K + + GPP ++ +V T + W P DG S I GY V+ ++ T
Sbjct: 11091 ETPKPIKALD--PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT 11148
Query: 977 MEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
+W ++ + C V+ L G Y FRV ENI GL G+ T P
Sbjct: 11149 QDWIK-FKTVTNLECVVTGLQQGKTYRFRVKAENIVGL----GLPDTTI----------P 11193
Query: 1037 FEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
E +E + + LI+ +VV AG + +RG P P W + EI+ D +
Sbjct: 11194 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11253
Query: 1096 I--TNYQGVLTLN--IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N+ VLT+ +RR D G Y N G L V
Sbjct: 11254 VETDNFSSVLTIKNCLRR----DTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 117 bits (293), Expect = 6e-26
Identities = 82/297 (27%), Positives = 135/297 (45%), Gaps = 18/297 (6%)
Query: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
+ +++ +G LR+ + G P P TW K D V I + +S + A R+
Sbjct: 21661 DGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGSTSLFVRDATRD 21719
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPV 670
G YT++ N G A I ++V D P +R T++ + L W+ P+ DG P+
Sbjct: 21720 HRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPI 21779
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
T Y++E+++ W + + + +Y + K+I G Y+ RV AVN GV +P +++ P
Sbjct: 21780 THYIIEKRETSRLAWALIEDKCEAQ-SYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDP 21837
Query: 731 F-------MPIAP-TSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+P AP EP ++T + TL W P G I Y++E + S
Sbjct: 21838 VVAQIQYTVPDAPGIPEP-----SNITGNSITLTWARPESDGGSEIQQYILERREKKSTR 21892
Query: 783 WVPA-NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
WV + P+ F V L G F V+ N AG + +++ + RE PP
Sbjct: 21893 WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 21949
Score = 117 bits (292), Expect = 8e-26
Identities = 112/425 (26%), Positives = 166/425 (39%), Gaps = 46/425 (10%)
Query: 729 KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
KP +P P ++VT TLKW PP G I Y++E + +WV
Sbjct: 13770 KPGIPTGPIK------FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC-A 13822
Query: 789 EPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPVTIREIAEPPKIRLP 843
V++ F V L G FRV N G +SEP P + + PP I
Sbjct: 13823 SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDV 13882
Query: 844 RH----LRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFV 899
RH L T +K G + K R ++W + ++ +R DF
Sbjct: 13883 RHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA------NKTPIRMRDF------ 13930
Query: 900 RQAARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
+ ++ EYE V N+ + + ++ PP V + + + W
Sbjct: 13931 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWT 13990
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
PK DG ++ GY V+K D + W N + TV+DL+ G +Y FR+ +N G
Sbjct: 13991 EPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAG 14050
Query: 1014 LSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC-AVR 1072
+P S T I K EY+ + P L + AG + LN ++
Sbjct: 14051 AISAPSESTETI-ICKD-------EYEAPTIVLDPTIKDGL---TIKAGDTIVLNAISIL 14099
Query: 1073 GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAE 1132
G P PK W K +IR IT+ L I+ + DAG YT A N G +
Sbjct: 14100 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 14159
Query: 1133 CKLEV 1137
K+ V
Sbjct: 14160 VKVTV 14164
Score = 115 bits (287), Expect = 3e-25
Identities = 132/509 (25%), Positives = 215/509 (42%), Gaps = 64/509 (12%)
Query: 159 DASGQSLESFKRTSEK---KSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIW 215
+ S + FKR +E+ ++ TA EL +K++ EE +K KD E+
Sbjct: 1946 EESEELRSKFKRRTEEGYYEAITAVELKS----RKKDESYEELLRKTKD--------ELL 1993
Query: 216 ELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLD--PAYQVDRGNK 273
K + E + +A + IT + K K+E+ S K + + V +G+
Sbjct: 1994 HWTKELTEEEKKALAEEGKIT-----IPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSD 2048
Query: 274 IKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVF----ENVGKKRILTINKCTLADDAAYEV 328
V + PD +W+KNG +I+ S + + +NV + L I T D A+ V
Sbjct: 2049 AHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE---LVIRDVTAEDSASIMV 2105
Query: 329 A---VKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAV---EVSEEGAQVMWMKDG 382
+ E + + LI E Q V ++ MA E SE +V W KDG
Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2165
Query: 383 VELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI---TNGGQCEAELIVEEKQL 439
+E+ D +YR D K H L + D Y + + A+LIVE +
Sbjct: 2166 MEVHEGD----KYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVV 2221
Query: 440 EVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
E ++++ D+ V S +C VS E + GKWY N VE++ + + TI+ L + D
Sbjct: 2222 EFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKD 2281
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V ED+G+Y+FV DG + K+ K P I S + V G
Sbjct: 2282 VTKEDQGEYSFVIDGKKTTCKLKM-----------KPRPIAILQGLSDQK------VCEG 2324
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+ ++L+V ++ E W+K G EV + I+K+ +IE +ED G Y+
Sbjct: 2325 DIVQLEVKVSLESVE-GVWMKDGQEVQPSDRVHIVIDKQ--SHMLLIEDMTKEDAGNYSF 2381
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ + + VDV P + V +
Sbjct: 2382 TIPALGLSTSGRVSVYSVDVITPLKDVNV 2410
Score = 114 bits (286), Expect = 4e-25
Identities = 137/562 (24%), Positives = 213/562 (37%), Gaps = 62/562 (11%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE-DVASIFLQVVDV---PDP 641
T T+ R R+ + S+ A G VGE S+F + D P P
Sbjct: 18650 TLTDLRLRVTGLTEGHSYEFRVAAENAAG---------VGEPSEPSVFYRACDALYPPGP 18700
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYES 700
P ++T L W P+YDGG PV GY+VE K+ + W + +
Sbjct: 18701 PSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18760
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTS-EP--------LHLIVEDVTDT 751
TK+ E Y R+ A+N+ GV +P+ T P +A EP L +V
Sbjct: 18761 TKLKENTEYNFRICAINSEGVGEPA--TLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18818
Query: 752 T----TTLKWRPPNRIGAGGIDGYLVEYC-LEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+K RP + +G L + +E + + + V R NL
Sbjct: 18819 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 18878
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ VN+ P+ +TIRE+ K + I + N +V +
Sbjct: 18879 SGSKTAFVNVRVLDSPSAPVN-LTIREVK---KDSVTLSWEPPLIDGGAKITNYIVEKRE 18934
Query: 867 KPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
R T R+ F V S EY + + E T
Sbjct: 18935 TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA-----SNEYGIGLPAET-----TEP 18984
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++V E PP V + +V A ++W+ P+ DG S+I GY V+ K + +W + +
Sbjct: 18985 VKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKW-STCTQV 19043
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP-FEYKEHDFR 1045
+ T+S L G EY FRV N G SD + ++ I KP E H F
Sbjct: 19044 KTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG---VPVIARDIEIKPSVELPFHTFN 19100
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
V A ++ +G P+ V W K+ ++E + +++ + V +L
Sbjct: 19101 -------------VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 19147
Query: 1106 NIRRPSPFDAGTYTCRAVNELG 1127
+I+ S D GTY N G
Sbjct: 19148 SIKEASKEDVGTYELCVSNSAG 19169
Score = 108 bits (271), Expect = 2e-23
Identities = 107/416 (25%), Positives = 166/416 (39%), Gaps = 37/416 (8%)
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
+P S L +D+ + + WRPP G I GY++E W ++ V
Sbjct: 23922 SPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGT 23980
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK--IRLPRHLRQT--- 849
VK L FRV N G S+P +PVT + PP+ P L T
Sbjct: 23981 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSS 24040
Query: 850 ----YIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDF-DTVFFVRQA 902
+ R + + V + + K W + T+ ++ T D + R
Sbjct: 24041 VSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRII 24100
Query: 903 ARSDSGEYELSVQIENM--KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDG 960
A++D G E S E + KD +K P + + + + ++W+ P+ DG
Sbjct: 24101 AQNDVGLSETSPASEPVVCKDP-------FDKPSQPGELEILSISKDSVTLQWEKPECDG 24153
Query: 961 NSEIMGYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
EI+GY+V+ W ER + T+ L+ EY FRV+ EN GLS
Sbjct: 24154 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP-- 24211
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKV 1079
+ TA +KT +T AP + D G +A L+C + G P P +
Sbjct: 24212 --RRTAMSIKTKLTSGE----------APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 24259
Query: 1080 VWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
W + E+ + K+ +++ TL + D G YTC A NE+GE KL
Sbjct: 24260 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24315
Score = 107 bits (266), Expect = 8e-23
Identities = 121/519 (23%), Positives = 189/519 (36%), Gaps = 75/519 (14%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF-EVFTETT 697
P PP ++ L W P YDGG P+ GYLVE K+ S W++ N + +T
Sbjct: 13284 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13343
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT----- 752
+E T ++E Y+ RV+AVN IG S PS P P + D+ T
Sbjct: 13344 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13403
Query: 753 ------TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RPP +I W N +R G +K+
Sbjct: 13404 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKSTDFDTF 13445
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ V AG+ TL +E K+ + G +N+ V
Sbjct: 13446 LRCENVNKYDAGKYI-LTLENSCGKKEYTIVVKV----------LDTPGPPVNVTVKEIS 13494
Query: 867 KPRPQVVWTK----GGAPLDTSRVHVRTSDFDTVFFV---------RQAARSDSGEYELS 913
K V W GG+P+ V R ++ + V R A + Y
Sbjct: 13495 KDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFR 13554
Query: 914 VQIEN---MKDTATIR--IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V EN + D R ++ + GP +++ V+ V ++ + W+ P DG S I+GY
Sbjct: 13555 VFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYV 13614
Query: 969 VQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
V ++ +W V ++ + DL G EY FRV EN + G +
Sbjct: 13615 VDFLTEEN-KWQRVM-KSLSLQYSAKDLTEGKEYTFRVSAEN----ENGEGTPSEITVVA 13668
Query: 1029 KTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI 1088
+ + + K P + + + L ++G P P V W K + +
Sbjct: 13669 RDDVVAPDLDLKG----------LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPL 13718
Query: 1089 REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
D + + + TL + DAG YT N G
Sbjct: 13719 ATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 13757
Score = 107 bits (266), Expect = 8e-23
Identities = 108/487 (22%), Positives = 190/487 (39%), Gaps = 42/487 (8%)
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTET-TYESTKMIEGILYEMRVFAVNAIGVSQPS 725
GKP+ + R + M+ N E+ E T + + + A N+ G ++
Sbjct: 20197 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20256
Query: 726 MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVP 785
+N P + P+ ++ D+T+ + TLKW PP G + Y++ + W
Sbjct: 20257 INIVVLDRPGPPTGPV--VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20314
Query: 786 ANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRL 842
+ V R V L TG FR+ N G S+ A VT++ PP
Sbjct: 20315 VSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSAC-VTVKLPYTTPGPPSTPW 20372
Query: 843 PRHLRQTYI-----RKVGEQLNLVVPF--QGKPRPQVVWTKGGA-PLDTSRVHVRTSDFD 894
++ + I V + VV + + K R ++W K + T+ V T
Sbjct: 20373 VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAG 20432
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
++ R A + +G + S E + ++ PP NV + ++ + + WQ
Sbjct: 20433 LIYEFRVYAENAAGVGKPSHPSEP--------VLAIDACEPPRNVRITDISKNSVSLSWQ 20484
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I GY V++ D W N T +S L ++Y FRV+ N G
Sbjct: 20485 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 20544
Query: 1014 LSDSPGVSKNTARILKT---GITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
+P + + + P EY E K+ AG S L
Sbjct: 20545 SISNPSEVVGPITCIDSYGGPVIDLPLEYTE-----VVKYR---------AGTSVKLRAG 20590
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
+ G P P + W K+ E++ + + N + ++ I+ ++G Y + N +G A
Sbjct: 20591 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 20650
Query: 1131 AECKLEV 1137
A ++++
Sbjct: 20651 ATIRVQI 20657
Score = 106 bits (265), Expect = 1e-22
Identities = 114/409 (27%), Positives = 180/409 (44%), Gaps = 52/409 (12%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
EIS+ D+ +W G+ ++PS + G KR LT++K L D A EV + T
Sbjct: 5114 EISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKL--DQAGEVLYQALNAITT 5171
Query: 339 --LFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-VSEEGAQVMWMKDGVELTREDSFKARY 395
L VKE + PL+D V V +R + E V A V+W K + D F
Sbjct: 5172 AILTVKEIELDFAVPLKD--VTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFD--- 5226
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQ 455
DGK+HIL+ +D +D G Y G + A L V +L+ + + D TVK E
Sbjct: 5227 -IIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGET 5285
Query: 456 AVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
A F CE+S EK+ W+KN ++ S+ + IS G+ HKL + +V +D
Sbjct: 5286 ATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQ--IKAQVK 5343
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
LS +A+L LE P + KT+ V +++ L ++ + P
Sbjct: 5344 ELSSTAQLKVLE---------ADPYFTVKLHDKTA------VEKDEITLKCEVSKDVP-- 5386
Query: 576 ATWLK-GDEVFTT------TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 628
W K G+E+ + +G RI K I+ A +D+G Y +
Sbjct: 5387 VKWFKDGEEIVPSPKYSIKADGLRRILK--------IKKADLKDKGEYVCDCGTDKTKAN 5438
Query: 629 ASIFLQVVDVPDPPEAVRITSVGE--DWAILVWEPPMYD----GGKPVT 671
++ +++ V P V + VGE + I + EP ++ G+P+T
Sbjct: 5439 VTVEARLIKVEKPLYGVEV-FVGETAHFEIELSEPDVHGQWKLKGQPLT 5486
Score = 103 bits (256), Expect = 1e-21
Identities = 109/405 (26%), Positives = 177/405 (43%), Gaps = 35/405 (8%)
Query: 249 KVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVG 308
KV+V + AA ++ G K + + IS ++W ++ + ++ KY G
Sbjct: 6239 KVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADG 6298
Query: 309 KKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE 368
KKR+L + TL D Y V V + L V E + IV PL+D +V V E
Sbjct: 6299 KKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCE 6357
Query: 369 VSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV-ITN--- 424
V+ EGA+ W ++ E DS ++Y + + L D +D+ Y V +TN
Sbjct: 6358 VNTEGAKAKWFRN--EEAIFDS--SKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6413
Query: 425 -GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKR 483
+ A LIVEE+ L +++ + D+ + F C+V+ VT KW KNG EV R
Sbjct: 6414 ENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNR 6473
Query: 484 ITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHL 543
++ H L I D DEG+Y V G S+ A+L +E E+V HL
Sbjct: 6474 VSYRVDKYKHMLTIKDCGFPDEGEY-IVTAGQDKSV-AELLIIEAPTEFVE-------HL 6524
Query: 544 DCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT-RIEKRVDCSS 602
+ T + V ++ E V + G E+ EG+ + EK
Sbjct: 6525 EDQTVTEFDDAV--------FSCQLSREKANVKWYRNGREI---KEGKKYKFEKDGSIHR 6573
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQ--VVDVPDPPEAV 645
+I+ + +DE Y V + + A +F++ V++ PP+ +
Sbjct: 6574 LIIKDCRLDDECEYACGVED--RKSRARLFVEEIPVEIIRPPQDI 6616
Score = 102 bits (254), Expect = 2e-21
Identities = 114/516 (22%), Positives = 191/516 (37%), Gaps = 76/516 (14%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP +RI + L W P+YDGG VTGY+VE ++ + W ++ +
Sbjct: 20859 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20918
Query: 696 TT-YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMP-------------------IA 735
TT Y + + G+ Y RV AVN G +P +P IA
Sbjct: 20919 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIA 20978
Query: 736 PTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERC 794
E + +++ T+ WR + G Y +E S +P T +
Sbjct: 20979 KAGEDVQVLIPFKGRPPPTVTWRKDEK-NLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 21037
Query: 795 GFTVKN---LPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
T++N P + + +V+ A + T+ + +PP I + I
Sbjct: 21038 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
K + + W+ ++ + T FF R A ++ G E
Sbjct: 21098 EK-------------RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 21144
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
E +K E P ++ +K+ T+ ++ W P DG S I Y V++
Sbjct: 21145 PCETTEPVK--------AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 21196
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
K W + ++ VS L + FRV+ +N GLSD
Sbjct: 21197 KGKGEQTWSHA-GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------- 21241
Query: 1032 ITFKPFEYKEHDFRMAPKFLTPLIDR--------VVVAGYSAALNCAVRGHPKPKVVWMK 1083
+T P KE +TP +D V G++ L +G PKP + W+K
Sbjct: 21242 VTIGPITVKE-------LIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLK 21294
Query: 1084 NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1119
+ + ++E + + +TL+I+ G YT
Sbjct: 21295 DGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21330
Score = 99.8 bits (247), Expect = 1e-20
Identities = 71/264 (26%), Positives = 127/264 (48%), Gaps = 11/264 (4%)
Query: 268 VDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K L ++S PD+T +KW+ N ++IKP + G K+ L IN+ +D+ Y
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2469
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMW-MKDGVEL 385
++ V + L V++ + I+ L D V VE+S G V+W KD
Sbjct: 2470 KLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKD---- 2523
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+E ++Y+ + GK + L +++++D G+Y +L V + + +
Sbjct: 2524 -KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPL 2580
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
D TV S++AVF+CEV++ G+W ++G + + I G +L+I + +D
Sbjct: 2581 TDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDI 2640
Query: 506 GDYTFVPDGYALSLSAKLNFLEIK 529
G+YT+ S K+ ++IK
Sbjct: 2641 GEYTYKVATSKTSAKLKVEAVKIK 2664
Score = 99.0 bits (245), Expect = 2e-20
Identities = 109/513 (21%), Positives = 188/513 (36%), Gaps = 49/513 (9%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV-FTETT 697
P PP ++ + L W P+YDGG + GY+VE+ W +T
Sbjct: 16533 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 16592
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP---LHLIVEDVTDTTT- 753
E K++E Y R+ A+N GV + + P + P L L + + +
Sbjct: 16593 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 16652
Query: 754 -------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RP + G +DG + + + + + V +G
Sbjct: 16653 GSLRLFVPIKGRPTPEVKWGKVDGEIRDAAI------IDVTSSFTSLVLDNVNRYDSGKY 16706
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF-Q 865
L + T + VT+R + P P +L+ T I K + P
Sbjct: 16707 TLTL--------ENSSGTKSAFVTVRVLDTPSP---PVNLKVTEITKDSVSITWEPPLLD 16755
Query: 866 GKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE---NMKDT 922
G + + + S V T+ + + Q S + ++ + E +
Sbjct: 16756 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16815
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I+V E PP + V +V + + W P+ DG S+I+ Y V+ K + +W
Sbjct: 16816 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16875
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
R + +++L G EY FRV N G SD R L I K
Sbjct: 16876 -ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP--------RSLAVPIVAK------- 16919
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P V G + + G PKP + W K+ + +++ + +T+ +
Sbjct: 16920 DLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDL 16979
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
TL+I+ D G Y N +G+ A ++
Sbjct: 16980 TTLSIKETHKDDGGQYGITVANVVGQKTASIEI 17012
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/541 (23%), Positives = 199/541 (36%), Gaps = 74/541 (13%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP + + L W+PP DGG P+ GY+VE +++G+ W ++N TT
Sbjct: 9400 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9459
Query: 699 EST--KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT--- 753
E + E Y RV AVN G S+PS T EP I D
Sbjct: 9460 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9519
Query: 754 --------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGA 805
+K RP + + DG + +G + +P + + +V +P
Sbjct: 9520 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 9577
Query: 806 RILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-- 863
R + ++ T V + ++ PPK L+ + I + +L+ +P
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 9632
Query: 864 ----------FQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + WTK ++ V + +F R A + G +
Sbjct: 9633 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG---IG 9689
Query: 914 VQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--- 970
+E ++ T T R + PPI + + + + W+ PK+DG S + Y V+
Sbjct: 9690 PPVETIQRT-TARDPIYPP-DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 9747
Query: 971 --KADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
K W +R+ TV DL+ G EY FRV N G+S
Sbjct: 9748 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVS------------ 9795
Query: 1028 LKTGITFKPFEYKEHDFRMAPKFLTPLID----RVVVAGYSAALNCAVRGHPKPKVVWMK 1083
K T P + + D + P ID V G + + ++G P P + W K
Sbjct: 9796 -KPSATVGPCDCQRPD-------MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9847
Query: 1084 -------NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
NK + D TL I + D G YT AVN LG A E +L
Sbjct: 9848 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9907
Query: 1137 V 1137
V
Sbjct: 9908 V 9908
Score = 97.4 bits (241), Expect = 7e-20
Identities = 101/436 (23%), Positives = 166/436 (38%), Gaps = 41/436 (9%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N+ G + ++N P + P+ + ++VT + TL W PP G I+ Y+VE
Sbjct: 15919 NSAGEAIETLNVIVLDKPGPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKR 15976
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS-----EPATLAQPVTI 831
+ W + V R L TG FR+ N G+S EP P +
Sbjct: 15977 DTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 16035
Query: 832 REIAEPPKIRLPRH--LRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVH 887
P + L + + + + + V+ + + K R ++W K ++
Sbjct: 16036 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVK------LNKTP 16089
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENM----KDTATIRIRVV-EKAGPPINVMVK 942
+ + F T + EYE V EN+ K + V + PP
Sbjct: 16090 IPQTKFKTT------GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAI 16143
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR-HTSCTVSDLIVGNE 1001
V + ++W+ P DG S+I GY V+K + W N T V+ L+ +
Sbjct: 16144 IVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHR 16203
Query: 1002 YYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVA 1061
Y FRV N G+ P S TG E M PK+ + VV A
Sbjct: 16204 YEFRVIARNAAGVFSEPSES--------TGAITARDEVDPPRISMDPKYKDTI---VVHA 16252
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
G S ++ + G P P + W+K E+ + I + +L+++ D+G Y +
Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16312
Query: 1122 AVNELGEALAECKLEV 1137
A N GE ++V
Sbjct: 16313 AKNVAGERSVTVNVKV 16328
Score = 95.5 bits (236), Expect = 3e-19
Identities = 116/453 (25%), Positives = 166/453 (36%), Gaps = 51/453 (11%)
Query: 694 TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT 753
T + + T +G Y + V N +G S+ P P+ +DV+ +
Sbjct: 16980 TTLSIKETHKDDGGQYGITV--ANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESI 17035
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813
TL W PP G I Y+V+ + W + V R V L TG FR+
Sbjct: 17036 TLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFA 17094
Query: 814 VNIAGRS---EPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLN------LVVPF 864
N G+S E + +E P + + + + E +N +
Sbjct: 17095 ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 17154
Query: 865 QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM---- 919
+ K R ++WTK ++ + +H DT F +A + G EYE V EN+
Sbjct: 17155 ERKERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVG 17201
Query: 920 ----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ + G P +MVK ++W P DG S I GY V+K D
Sbjct: 17202 KASKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLP 17258
Query: 976 TMEWFNVYERNR-HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF 1034
W N T TVS L Y FRV +N G P S TG
Sbjct: 17259 DGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDS--------TGPIT 17310
Query: 1035 KPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF 1094
E + M PKF + VV AG + L V G P P + W++ EI E +
Sbjct: 17311 AKDEVELPRISMDPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARC 17367
Query: 1095 LITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
I N L ++ D G Y RA N G
Sbjct: 17368 EIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 17400
Score = 94.4 bits (233), Expect = 6e-19
Identities = 72/213 (33%), Positives = 98/213 (46%), Gaps = 16/213 (7%)
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHT 989
EK G P + V + +V W+ P DG ++I Y+++K +KK +W +V E R T
Sbjct: 24518 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24577
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK 1049
+V +LI G EY FRV EN+ G S+ +S +P K AP
Sbjct: 24578 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-------------EPITPKSDVPIQAPH 24624
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP-KFLITNYQ-GVLTLNI 1107
F L + V +A L C V GHPKP V W + EI D K+ I ++ G L I
Sbjct: 24625 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 24684
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
+ DA Y RA N+ G LEV VP
Sbjct: 24685 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24717
Score = 94.0 bits (232), Expect = 7e-19
Identities = 95/391 (24%), Positives = 171/391 (43%), Gaps = 37/391 (9%)
Query: 240 GMLKRLKKAKVEVKK-SAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQ-EIK 297
G ++ AK+ V++ F K L+ V +G + L E++ + + W K+G+ ++
Sbjct: 4890 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVE 4948
Query: 298 PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFT-ELFVKEPPVL---IVTPLE 353
+ V +G R LTIN D Y V V++ VK V+ +V P+
Sbjct: 4949 KPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIR 5008
Query: 354 DQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQ 413
DQ V A +++++ + W K E+ E + K +DG L + +
Sbjct: 5009 DQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTE--ILRDGNHLYLKIKNAMP 5066
Query: 414 EDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYK 473
ED Y V G + A+L + E+++E+L+ I D+T+ E A F E+S+ + G+W
Sbjct: 5067 EDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKL 5126
Query: 474 NGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEY- 532
G +RPS I G L + V+ + G+ + +A L EI++++
Sbjct: 5127 KGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLY--QALNAITTAILTVKEIELDFA 5184
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
VP ++ + V + R + +T E + W KG ++ +++
Sbjct: 5185 VPLKD----------------VTVPERRQARFECVLTREANVI--WSKGPDIIKSSDKFD 5226
Query: 593 RI---EKRVDCSSFVIESAQREDEGRYTIKV 620
I +K + VI +Q +DEG YT +V
Sbjct: 5227 IIADGKKHI----LVINDSQFDDEGVYTAEV 5253
Score = 92.8 bits (229), Expect = 2e-18
Identities = 113/454 (24%), Positives = 174/454 (38%), Gaps = 76/454 (16%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
NA G S+ K P + L V VT TL W P G I Y+VE
Sbjct: 22819 NASGTKAVSVMVKVLDSPGPCGK---LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERR 22875
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE--- 833
WV E + V L +FRV VN G P ++P+ R
Sbjct: 22876 ETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFT 22933
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVR 889
I PP I +VG GK + WTK GG + V R
Sbjct: 22934 IPSPPGIP----------EEVGT---------GKEHIIIQWTKPESDGGNEISNYLVDKR 22974
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE------------------ 931
++ + R D Y+ +++ ++ + + RV
Sbjct: 22975 EKK--SLRWTR--VNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISC 23030
Query: 932 -----KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
GPP V + + + W P DG ++I+GY ++ +K T +W+ V+
Sbjct: 23031 REPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNA 23090
Query: 987 --RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKE-HD 1043
R+T TV DL +G +Y FRV N+ G+S+ S++ A I +P E E D
Sbjct: 23091 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSE---YSESIAEI-------EPVERIEIPD 23140
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+A + R AG S L +V G P P + W K +++ + +I +
Sbjct: 23141 LELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITWSKQGIDLAS--RAIIDTTESYS 23195
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L + + + +DAG YT A N+ G+ A ++V
Sbjct: 23196 LLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23229
Score = 91.7 bits (226), Expect = 4e-18
Identities = 62/245 (25%), Positives = 116/245 (47%), Gaps = 7/245 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G+ ++L V++S + W K+GQE++PS + + +L I T D Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVEL 385
+ T V V ++TPL+D V G + + +VS + V W + ++
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+D +A + G + L+ + D G Y++I + L VE+ +++++ +
Sbjct: 2440 KPDDRVQAIVK----GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEK--IKIIRGL 2493
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
DLT ++ VF+ E+S + W E++PS + I G+ +KL + ++ +DE
Sbjct: 2494 RDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDE 2553
Query: 506 GDYTF 510
G YTF
Sbjct: 2554 GKYTF 2558
Score = 91.3 bits (225), Expect = 5e-18
Identities = 106/430 (24%), Positives = 163/430 (37%), Gaps = 59/430 (13%)
Query: 734 IAPTSEPLHLI-VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
+ P S+P I +++ + L W P G G I Y +E W + V
Sbjct: 21349 LGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VA 21407
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
R F V NL A FRV N G ++QP+ I + R+P + I
Sbjct: 21408 RTTFKVPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPGPPGKPVIY 21461
Query: 853 KV---GEQLNLVVPF------------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
V G L P + K R ++W K ++TS + R
Sbjct: 21462 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK----VNTSPISGRE------- 21510
Query: 898 FVRQAARSDSGEYELSVQIENMKDTA--------TIRIRVVEKAGPPINVMVKEVWGTNA 949
R + +Y+ V EN + T+ + V+ G P + +V
Sbjct: 21511 -YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETI 21566
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYT 1008
++W P DG S+I+GY ++K W + TV+ L G+ Y FR+
Sbjct: 21567 TLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21625
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALN 1068
N G P S +GI E P++ LI + +G S +
Sbjct: 21626 RNAVGTISPPSQS--------SGIIMTRDENVPPIVEFGPEYFDGLI---IKSGESLRIK 21674
Query: 1069 CAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
V+G P P+V W K+ +EI + IT+ G +L +R + G YT A N G
Sbjct: 21675 ALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGS 21734
Query: 1129 ALAECKLEVR 1138
A AE K++V+
Sbjct: 21735 AKAEIKVKVQ 21744
Score = 90.1 bits (222), Expect = 1e-17
Identities = 105/434 (24%), Positives = 163/434 (37%), Gaps = 37/434 (8%)
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
E ++ NA G +++ P + P++++ DVT T+ W+PP G +
Sbjct: 11275 EYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVI 11332
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
Y+VE + W ++ + + +L G +FRV N G P V
Sbjct: 11333 NYIVEKQDTRKDTWGVVSSGS-SKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV 11391
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
+ + P P T I + ++ +P P + + V V
Sbjct: 11392 AKHKFSPPSP---PGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11448
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPINVMV 941
+ + F R + YE V EN+ + R ++ GPPIN +
Sbjct: 11449 KTPIADLKF-RVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKL 11507
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEW--FNVYERNRHTSCTVSDLIVG 999
K+ A + W P DG S I+GY V+ T +W N E R + V LI G
Sbjct: 11508 KDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 11567
Query: 1000 NEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVV 1059
NEY FR+ NI G + R L + K D P+ + R V
Sbjct: 11568 NEYRFRIKAANIVG--------EGEPRELAESVIAK-------DILHPPEVELDVTCRDV 11612
Query: 1060 VA---GYSAALNCAVRGHPKPKVVWMK-NKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ G + + V+G P+P + W K K+ +RE LI + V L I+ D
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADH 11671
Query: 1116 GTYTCRAVNELGEA 1129
G Y A N G A
Sbjct: 11672 GKYIISAKNSSGHA 11685
Score = 89.4 bits (220), Expect = 2e-17
Identities = 103/435 (23%), Positives = 167/435 (38%), Gaps = 40/435 (9%)
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
YE+++ NA+G + ++ + P P+ + VT TL WRPP G I
Sbjct: 20638 YELKLR--NAMGSASATIRVQILDKPGPPGGPIEF--KTVTAEKITLLWRPPADDGGAKI 20693
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE W + E +E C T + G +FRV VN G EP
Sbjct: 20694 THYIVEKRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSV 20752
Query: 829 VTIREIAEPPKIRLPRHLRQT-------YIRKVGEQLNLVVPF--QGKPRPQVVWTKG-G 878
V P +P + T + R + + + + + + + + + W K
Sbjct: 20753 VAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLK 20812
Query: 879 APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN 938
+ +R V ++ + R A + +G+ S E K I + GPP
Sbjct: 20813 ETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI-----DPPGPPAK 20867
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSDL 996
+ + + ++ + W P DG S + GY V+ + EW V + R T VS+L
Sbjct: 20868 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 20927
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G YYFRV N G + +++ P + K D AP+ +
Sbjct: 20928 KPGVNYYFRVSAVNCAGQGEPIEMNE-------------PVQAK--DILEAPEIDLDVAL 20972
Query: 1057 RVVV---AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPF 1113
R V AG + +G P P V W K++ + D ++ I N L I + +
Sbjct: 20973 RTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN 21032
Query: 1114 DAGTYTCRAVNELGE 1128
D G Y N +GE
Sbjct: 21033 DTGKYILTIENGVGE 21047
Score = 89.4 bits (220), Expect = 2e-17
Identities = 134/655 (20%), Positives = 251/655 (38%), Gaps = 101/655 (15%)
Query: 23 KEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPD 82
K++ K + ++ P+ P + +P V + +V + A K G+
Sbjct: 26520 KKSDQKTTESTVTRKTEPKAPEPISSKP--VIVTGLQDTTVSSDSVAKFAVKATGEP--- 26574
Query: 83 KPTIKWFK-GKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAK 141
+PT W K GK + G K +K S D+G + LE+
Sbjct: 26575 RPTAIWTKDGKAITQGGK------YKLSE-------------------DKGGFFLEIHKT 26609
Query: 142 DTCDSCGFNIDVEAPRQDASGQ---SLESFKRTSEKKSDTAGELDFSGLLKKREVVEEE- 197
DT DS + V+ S ++++ K T +K T + + +K+ VV+EE
Sbjct: 26610 DTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITP--QKKAVVQEEI 26667
Query: 198 ----------KKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKK 247
K + K + L + E ++L + + + + I + + + +
Sbjct: 26668 SQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSI--VHEEITKTSQ 26725
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
A EV+ A K ++ G ++ L I+ +KW NG E+ S +Y +
Sbjct: 26726 ASEEVRTHAEI-KAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNSEEYRYGVS 26783
Query: 308 GKKRILTINKCTLADDAAYEVAVKDE----KCFTELF----VKEPPVLIVTPLEDQQVFV 359
G + LTI + + D+ K + KC +L + + P I P Q +
Sbjct: 26784 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RSQNINE 26842
Query: 360 GDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGR 418
G V E+S E ++ W K+ + + S + + + L + D G+
Sbjct: 26843 GQNVLFTCEISGEPSPEIEWFKNNLPI----SISSNVSISRSRNVYSLEIRNASVSDSGK 26898
Query: 419 YQVITNG--GQCEAEL------IVEEKQLE-VLQDIADLTVKAS------EQAVFKCEVS 463
Y + GQC A +VEE E VL+ D +++ S + + K E S
Sbjct: 26899 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26958
Query: 464 DEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG--DYTFVPDGYALSLSA 521
+ + E++ + ++ + + ++ G + T + + L A
Sbjct: 26959 FSSFSSSSASSMTEMKFAS-MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKA 27017
Query: 522 KLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW-LK 580
+ + K+E +P I + G L + + TGEP P TW
Sbjct: 27018 GIRGIPPKIEALPSD-----------------ISIDEGKVLTVACAFTGEPTPEVTWSCG 27060
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
G ++ + +GR IE D ++ +I Q++D G YT+ + N G D A++ + +
Sbjct: 27061 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 88.2 bits (217), Expect = 4e-17
Identities = 106/434 (24%), Positives = 168/434 (38%), Gaps = 44/434 (10%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ AVN +G + M P P+ E V+ TL W PP G I Y+
Sbjct: 9891 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKF--ESVSADQMTLSWFPPKDDGGSKITNYV 9948
Query: 773 VEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR 832
+E + WV ++EP E C +T+ L G +FR++ N G EP ++P T R
Sbjct: 9949 IEKREANRKTWVHVSSEPKE-CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD-SEPETAR 10006
Query: 833 EIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-FQGKPRPQVVWTKGGAPLDTSRVHVRTS 891
+ P P + + + +N P + G W + DT+ +
Sbjct: 10007 NLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLE---MKDTTSKRWKRV 10061
Query: 892 DFDTVFFV------RQAARSDSGEYELSVQIENM---------KDTATIRIRVVEKAGPP 936
+ D + + + + +Y+ V N D AT R + GPP
Sbjct: 10062 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP-GPP 10120
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSD 995
V + ++A +EW P DG S++ GY V+ ++ EW ++ R T V+
Sbjct: 10121 FP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTG 10179
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G Y FRV NI G+ + PG + E K+ + +
Sbjct: 10180 LKEGAFYKFRVRAVNIAGIGE-PGEVTDV------------IEMKDRLVSPDLQLDASVR 10226
Query: 1056 DRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
DR+VV AG + V G P P V W N+ + ++ T ++ I+
Sbjct: 10227 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSH 10284
Query: 1115 AGTYTCRAVNELGE 1128
G Y+ A NE GE
Sbjct: 10285 QGVYSLLAKNEAGE 10298
Score = 88.2 bits (217), Expect = 4e-17
Identities = 118/461 (25%), Positives = 169/461 (36%), Gaps = 66/461 (14%)
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRI 763
I+G Y +R A N G +N K P P+ V VT +L W PP +
Sbjct: 17386 IDGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQ--VTGVTSEKCSLTWSPPLQD 17441
Query: 764 GAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPA 823
G I Y+VE W +E V V L G +FR++ VN G EP
Sbjct: 17442 GGSDISHYVVEKRETSRLAWTVVASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPL 17500
Query: 824 TLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG--------------EQLNLVVPFQGKPR 869
A + P P+ L T I K E + +V + + R
Sbjct: 17501 ESAPVLMKNPFVLPGP---PKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV--EKRDR 17555
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT-----AT 924
+ W K + R+ T +R ++ EYE V EN AT
Sbjct: 17556 SGIRWIK----CNKRRI--------TDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17603
Query: 925 IRIRVVE---KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEW 979
+ + + K GPP N + + + + W P DG SEI+GY V+ KAD++ +
Sbjct: 17604 VYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQI 17663
Query: 980 FNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEY 1039
R T +S L EY RV N GL ++ V P
Sbjct: 17664 VTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV---------------PGTV 17708
Query: 1040 KEHDFRMAPKFLTPLIDR---VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLI 1096
K D AP+ R VV AG SA ++ +G P P++ W + + E + K I
Sbjct: 17709 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQI 17766
Query: 1097 TNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+I DAG Y + N G A ++V
Sbjct: 17767 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17807
Score = 87.4 bits (215), Expect = 7e-17
Identities = 103/433 (23%), Positives = 161/433 (37%), Gaps = 50/433 (11%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++N K P P+ ++ VT TL W+PP + G I Y+VE
Sbjct: 16313 AKNVAGERSVTVNVKVLDRPGPPEGPV--VISGVTAEKCTLAWKPPLQDGGSDIINYIVE 16370
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPV 829
W + V+ V L G FR++ VN G SEP P
Sbjct: 16371 RRETSRLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPF 16429
Query: 830 TIREIAEPPKIRLPRHLRQTYI----RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR 885
+ + + P++ + G L + + + + WT R
Sbjct: 16430 VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT---------R 16480
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPI 937
H R +R ++ +YE V EN + + K GPP
Sbjct: 16481 CHKRLIG---ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN 16537
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSD 995
N V ++ ++ + W P DG EI GY V+K D EW T+ V
Sbjct: 16538 NPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEK 16597
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L+ +EY FR+ N G+ + V I + E + D + L +I
Sbjct: 16598 LLEKHEYNFRICAINKAGVGEHADVPGPI-------IVEEKLEAPDIDLDLE---LRKII 16647
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRPSPFD 1114
+ + AG S L ++G P P+V W K EIR+ +T ++ ++ N+ R +D
Sbjct: 16648 N--IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNR---YD 16702
Query: 1115 AGTYTCRAVNELG 1127
+G YT N G
Sbjct: 16703 SGKYTLTLENSSG 16715
Score = 87.4 bits (215), Expect = 7e-17
Identities = 98/404 (24%), Positives = 147/404 (36%), Gaps = 63/404 (15%)
Query: 713 VFAVNAIGVSQPSMNT----KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
V A N+ G + +++ KP P+ P ++V+ + W PP G I
Sbjct: 18079 VTATNSAGTATENLSVIVLEKPGPPVGPVR------FDEVSADFVVISWEPPAYTGGCQI 18132
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE + W + V R + L TG FR+ N G+S P
Sbjct: 18133 SNYIVEKRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV 18191
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV---------------VPFQGKPRPQVV 873
+ EP P ++ + + LV + K + ++
Sbjct: 18192 IVQYPFKEPGPPGTP------FVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18245
Query: 874 WTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM----KDTATIRIR 928
W K ++ ++ + F T D G EYE V EN+ K +
Sbjct: 18246 WVK------LNKTPIQDTKFKTTGL-------DEGLEYEFKVSAENIVGIGKPSKVSECF 18292
Query: 929 VV-EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN- 986
V + PP + N ++W+ P DG S+I GY V+K D W N
Sbjct: 18293 VARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18352
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
T TVS L+ Y FRV N G P S IT + E + +
Sbjct: 18353 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGA-------ITARD-EIDAPNASL 18404
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRE 1090
PK+ + VV AG + L +RG P P VVW K+ E+ E
Sbjct: 18405 DPKYKDVI---VVHAGETFVLEADIRGKPIPDVVWSKDGKELEE 18445
Score = 86.7 bits (213), Expect = 1e-16
Identities = 91/398 (22%), Positives = 151/398 (37%), Gaps = 28/398 (7%)
Query: 633 LQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV 692
L +D P P + IT L W P Y GG +T Y+VE++ + RW+K NF
Sbjct: 15049 LDPIDPPGKPVPLNIT---RHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSN 15105
Query: 693 FTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT 752
E + + + E YE RV A NA G P + E + V+ T
Sbjct: 15106 ILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDT 15165
Query: 753 TTLKWRPPNRIGA--GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
LK R+ A G +E+ +G E A E ++ F+ + + R
Sbjct: 15166 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE-IKIADFSTNLVNKDS--TRR 15222
Query: 811 VVGVNIAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKV-----------GEQL 858
G + P A+ + ++ + P P + + K G ++
Sbjct: 15223 DSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15282
Query: 859 NLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN 918
+ + Q + ++ WT + + +++ V + R A + G E
Sbjct: 15283 DHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG------EP 15335
Query: 919 MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTME 978
++ + + PP N V + + +V W P DG SEI+ Y V++ DK
Sbjct: 15336 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 15395
Query: 979 WFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
W ++ VS L G+EY FR+ EN G+S
Sbjct: 15396 WIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 15433
Score = 86.7 bits (213), Expect = 1e-16
Identities = 227/1140 (19%), Positives = 382/1140 (33%), Gaps = 202/1140 (17%)
Query: 83 KPT--IKWF-KGKWLELGSK------SGA-RFSFKESHNSASNVYTVELHIGKVVLGDRG 132
KPT +KW+ G L+ SK SG + H S Y K D
Sbjct: 26095 KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASD-- 26152
Query: 133 YYRLEVKAKDTCDSCGFNIDVEAPRQ------DASGQSLESFKRTSEKKSDTAGELDFSG 186
Y L+V D D E PR ++ SFK+TSE ++ ++ S
Sbjct: 26153 YATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQ 26212
Query: 187 LLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLK 246
+ + RE + + + + + E +KS KI T +L + +
Sbjct: 26213 MTETRESLSSYEHSASAEMKSAALEEKSLE-----EKSTTRKIK----TTLAARILTKPR 26263
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFEN 306
V +SA F+ D +P T+ W + GQ + S+++
Sbjct: 26264 SMTVYEGESARFSCDTD-----------------GEPVPTVTWLRKGQVLSTSARHQVTT 26306
Query: 307 VGKKRILTINKCTLADDAAYEVAV-----KDEKCFTELFVKEPPVLIVTPLEDQQVFVGD 361
K I+ +D+ Y V V K E FT K + ++ V
Sbjct: 26307 TKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK-------ARVTEKAVTSPP 26359
Query: 362 RVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
RV+ + ++ K+ R K H S + +V
Sbjct: 26360 RVKSPEP---------------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKV 26404
Query: 422 ITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPS 481
+ I + + E ++IA LT + EV+ WYK+G +++ +
Sbjct: 26405 QHLPVSAPPK-ITQFLKAEASKEIAKLTCVVESSVLRAKEVT-------WYKDGKKLKEN 26456
Query: 482 KRITISH-VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE----------IKV 530
+ ++L I+++ D+G+Y G + L F+ K+
Sbjct: 26457 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 26516
Query: 531 EYVPKQEPPKIHLDCSGKTSENAI-------VVVAG---------NKLRLDVSITGEPPP 574
K + + KT A V+V G + + V TGEP P
Sbjct: 26517 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 26576
Query: 575 VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
A W K + T G+ ++ + I D G YT V N G +S L
Sbjct: 26577 TAIWTKDGKAITQG-GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLT 26635
Query: 635 VVDVPDPPEAVRITS------VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKL 688
+ + D EA ++++ + A++ E K + ++ + SQ + L
Sbjct: 26636 IKAIKDT-EAQKVSTQKTSEITPQKKAVVQEEISQ----KALRSEEIKMSEAKSQEKLAL 26690
Query: 689 NFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
E E K E + SQ S K F +E
Sbjct: 26691 KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQR 26750
Query: 743 LIVEDVTDTTTTLKW---------RPPNRIGAGGIDGYLV----EYCLEGSEEWVPANTE 789
L+++ T +KW R G G D L + EG + E
Sbjct: 26751 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26810
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
+ +C + + T ++ L PA ++QP R
Sbjct: 26811 GIVKCQYDL----TLSKEL----------SDAPAFISQP------------------RSQ 26838
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSG 908
I + G+ + G+P P++ W K P+ +S V + S +R A+ SDSG
Sbjct: 26839 NINE-GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 26897
Query: 909 EYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
+Y + + + +AT + V+ P +V G +L
Sbjct: 26898 KYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL----------QGSFSSQS 26947
Query: 969 VQKADKKTMEWFNVYERNRHTSCT--------VSDLIVGNEYYFRVYTENICGLSDSPGV 1020
VQ + K F+ + + +S T + E + + + + G+S+ +
Sbjct: 26948 VQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQL 27007
Query: 1021 SKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVV 1080
+T+++LK GI P PK D + G + CA G P P+V
Sbjct: 27008 ESSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 27056
Query: 1081 WM--KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
W K+ +E +F I N + TL I D G YT NE G A + +R
Sbjct: 27057 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 27116
Score = 84.7 bits (208), Expect = 4e-16
Identities = 109/433 (25%), Positives = 158/433 (36%), Gaps = 52/433 (12%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G ++N K P + PL + +T +L W P G ID Y+VE
Sbjct: 19561 NVAGTRSVAVNCKVLDKPGPPAGPLE--INGLTAEKCSLSWGRPQEDGGADIDYYIVEKR 19618
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
W E ++ V L G +FRV GVN G EP + V I+ +
Sbjct: 19619 ETSHLAWTICEGE-LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKALDP 19674
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---- 892
P L T + K E + L RP+ + GG+ + + R +
Sbjct: 19675 FTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERREKNSLRW 19724
Query: 893 --------FDTVFFVRQAARSDSGEYELSVQIEN-----MKDTATIRIRVVEKA---GPP 936
+D V+ + EYE V EN + + IR + PP
Sbjct: 19725 VRVNKKPVYD--LRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPP 19782
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ + T + W P DG + I GY V+ +W + R T T+S L
Sbjct: 19783 SKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 19842
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G EY FRV + N G SD S +I K +E F + + LI
Sbjct: 19843 TTGAEYVFRVKSVNKVGASDPSDSSD--PQIAKE-------REEEPLFDIDSEMRKTLI- 19892
Query: 1057 RVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAG 1116
V AG S + RG P P V+W K ++R + + +L I + D+G
Sbjct: 19893 --VKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIENANRNDSG 19948
Query: 1117 TYTCRAVNELGEA 1129
YT N L A
Sbjct: 19949 KYTLTIQNVLSAA 19961
Score = 84.3 bits (207), Expect = 6e-16
Identities = 200/926 (21%), Positives = 340/926 (36%), Gaps = 134/926 (14%)
Query: 286 TLKWFK-NGQEIKPSSKYVFENV--GKKRILTINKCTLADDAAYEVAVKDEKCFTELFV- 341
T KW + N + IK V E V K+ +L + A + V + +E V
Sbjct: 8023 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVR-------AVNAIGVSEPSEISENVVA 8075
Query: 342 KEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQV---MWMKDGVELTREDSFKARYRFK 398
K+P LE + V + ++++ V V W KDG E+ D R K
Sbjct: 8076 KDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD----RLTMK 8131
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
D L V+ D G Y + A + K + + D +KAS+
Sbjct: 8132 NDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD--IKASDITKS 8189
Query: 459 KCEVSDEKVTGKWYKNGVEV--------RPSKRITISHVGRFHKL--VIDDVRPEDEGDY 508
C+++ E + G + +R I + +KL + D+ P G+Y
Sbjct: 8190 SCKLTWEPPE---FDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPN--GEY 8244
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYV---PKQEP-PKIHLDCSGKTSENAIVVVAGNKLRL 564
F A++ ++E+K + PKQ P P + ++ T+E
Sbjct: 8245 FFRVK--AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA------------ 8290
Query: 565 DVSITGEPPPV--ATWLKGDEVFTTTEGRTRI----EKRVDCSSFVIESAQREDEGRYTI 618
++IT +PP + + G + +G R E V ++ + + E ++ +
Sbjct: 8291 -MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRV 8349
Query: 619 KVTNPVG---EDVASIFLQVVDVPDPPEAVRITSV---------------GEDWAILVWE 660
+ N G A+ + VD D P+ + TS+ G + + W
Sbjct: 8350 RAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWI 8409
Query: 661 PP----MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL-------- 708
+ + K LV R+K Q + + +++K E L
Sbjct: 8410 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 8469
Query: 709 ----YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y ++V N G+++ P P++ + ED+ T+ KW PP G
Sbjct: 8470 DHGLYMIKV--ENDHGIAKAPCTVSVLDTPGP---PINFVFEDIRKTSVLCKWEPPLDDG 8524
Query: 765 AGGIDGYLVEYC--LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEP 822
I Y +E + EW+ T + C ++V L G LFRV N G P
Sbjct: 8525 GSEIINYTLEKKDKTKPDSEWIVV-TSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8583
Query: 823 ATLAQPVTIREIAEPP----KIRLPRHLRQTYIRKVGEQLNLVVPFQG-----KPRPQVV 873
+++P+ ++ PP K + + + K E + P G +
Sbjct: 8584 C-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTH 8642
Query: 874 WTK-GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W++ + L+ + +V + R A + +G + S D T +
Sbjct: 8643 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP----SDPKTAH-DPISP 8697
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSC 991
GPPI V + T +EW+ P +G EI+GYFV K T EW E+ +
Sbjct: 8698 PGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQY 8756
Query: 992 TVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
TV ++ G +Y RV N G PG ++ +P E + ++ K
Sbjct: 8757 TVKEIREGADYKLRVSAVNAAG-EGPPGETQPVT-------VAEPQEPPAVELDVSVKGG 8808
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
++AG + + V G P P VW K + E+ +D + +I N L I+
Sbjct: 8809 IQ-----IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDAL 8862
Query: 1112 PFDAGTYTCRAVNELGEALAECKLEV 1137
D G Y A N G A ++EV
Sbjct: 8863 RKDHGRYVITATNSCGSKFAAARVEV 8888
Score = 84.3 bits (207), Expect = 6e-16
Identities = 117/447 (26%), Positives = 169/447 (37%), Gaps = 58/447 (12%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++ N K P PL V +VT L W PP G ID Y+V+
Sbjct: 15231 ATNPGGFAKHIFNVKVLDRPGPPEGPL--AVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 15288
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
W +E V+ V L G +FRV+ VN G EP ++PV
Sbjct: 15289 KRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-SEPVLAVNP 15346
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFD 894
PP P++ T I K + +V G P + GG+ + V R
Sbjct: 15347 YGPPDP--PKNPEVTTITK-----DSMVVCWGHPD-----SDGGSEIINYIVERRDKAGQ 15394
Query: 895 ----------TVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPP 936
T + + ++ EYE + EN + V K GPP
Sbjct: 15395 RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPP 15454
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVS 994
N V + ++ + W P DG SEI GY V+ A + EW V + TS T++
Sbjct: 15455 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 15514
Query: 995 DLIVGNEYYFRVYTENICGLSDS---PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
L EY R+Y N GL + PG K R+L I + D R K +
Sbjct: 15515 GLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIEL------DADLR---KVV 15565
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRP 1110
T + A + L ++G P P+V W ++ E + T +Y ++ N+ R
Sbjct: 15566 T------IRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNR- 15618
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
FD+G Y N G A + V
Sbjct: 15619 --FDSGKYILTVENSSGSKSAFVNVRV 15643
Score = 84.3 bits (207), Expect = 6e-16
Identities = 106/412 (25%), Positives = 143/412 (34%), Gaps = 70/412 (16%)
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
++T TL W P G I Y++E W + E +T L G
Sbjct: 21758 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNE 21816
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRLPRHLRQTYIRKV--------G 855
FRV VN G P + PV + + + P I P ++ I G
Sbjct: 21817 YQFRVSAVNKFGVGRPLD-SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGG 21875
Query: 856 EQLNLVVPFQGKPRPQVVWTK--GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
++ + + + + W K P+ +R V ++ EYE
Sbjct: 21876 SEIQQYI-LERREKKSTRWVKVISKRPISETRFKV-------------TGLTEGNEYEFH 21921
Query: 914 VQIENMKDTAT-------IRIRV-VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
V EN I+ R V GPP V V + T +EW P DG EI+
Sbjct: 21922 VMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21981
Query: 966 GYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS------- 1017
GY ++ +W V E T TV+DL G EY FRV N G DS
Sbjct: 21982 GYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTI 22041
Query: 1018 PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKP 1077
V + TA L FK VV AG S L A +G P P
Sbjct: 22042 KAVDRLTAPELDIDANFKQ-------------------THVVRAGASIRLFIAYQGRPTP 22082
Query: 1078 KVVWMK--NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
VW K + + +R D I TL + + DAG YT N G
Sbjct: 22083 TAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNRNDAGKYTLTVENNSG 22130
Score = 84.0 bits (206), Expect = 8e-16
Identities = 108/447 (24%), Positives = 166/447 (37%), Gaps = 71/447 (15%)
Query: 720 GVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEG 779
G Q ++ +P P+ P S ++VT + W+PP G I Y++E G
Sbjct: 10597 GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG 10650
Query: 780 SEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK 839
+ W+P T + V L G +FR+ N+ G S+P + + +
Sbjct: 10651 KDVWMPV-TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP------LVSDSMKAKDR 10703
Query: 840 IRLPRHLRQTYIRKVGEQLNLVV---PFQG-KPRPQVV------WTKGGAPLDTSRVHVR 889
R+P Q + +V + LV P G KP + +K A + +H
Sbjct: 10704 FRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPY 10763
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRV-----VEKAGPPINVMV 941
T R + +YE V EN + D + V + K PP+N
Sbjct: 10764 TK-------FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEA 10816
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT--SCT-----VS 994
+ + + WQ P+ DG S+I+GY V+ EW R HT SC V+
Sbjct: 10817 IDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW----RRANHTPESCPETKYKVT 10872
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL--- 1051
L G Y FRV N G SD V + P K+ R+ P L
Sbjct: 10873 GLRDGQTYKFRVLAVNAAGESDPAHVPE-------------PVLVKD---RLEPPELILD 10916
Query: 1052 -TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110
++ + G + L+ ++G P PKV W K + + +T L IR
Sbjct: 10917 ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNA 10974
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D G Y+ N G K+ V
Sbjct: 10975 AHEDGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 84.0 bits (206), Expect = 8e-16
Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 24/234 (10%)
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++ R A ++ G + V +E + ++ E PP V + +V T+A + W+
Sbjct: 17879 IYYFRVMAENEFG---VGVPVETVD-----AVKAAEPPSPPGKVTLTDVSQTSASLMWEK 17930
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG S ++GY V+ K T +W V E ++ + V+ L G EY FRV N G S
Sbjct: 17931 PEHDGGSRVLGYVVEMQPKGTEKWSIVAE-SKVCNAVVTGLSSGQEYQFRVKAYNEKGKS 17989
Query: 1016 DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHP 1075
D R+L + K D + P P + AG + V G P
Sbjct: 17990 DP--------RVLGVPVIAK-------DLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRP 18034
Query: 1076 KPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
+P + W+K+ +++ + + L+I+ + D G YT A N G A
Sbjct: 18035 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 18088
Score = 82.8 bits (203), Expect = 2e-15
Identities = 100/415 (24%), Positives = 149/415 (35%), Gaps = 52/415 (12%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ D+ +L W P G I Y+VE C +WV A V + V L G
Sbjct: 12696 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTKTSCRVGKLIPG 12754
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV---------- 854
+FRV N G SEP T + V P + P++ R T + K
Sbjct: 12755 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSE---PKNARVTKVNKDCIFVAWDRPD 12811
Query: 855 --GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
G + + K R ++W K L VR++++ V + EY
Sbjct: 12812 SDGGSPIIGYLIERKERNSLLWVKANDTL------VRSTEYPCAGLV------EGLEYSF 12859
Query: 913 SVQIENM-------KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
+ N K T + R+ PP V +V + + W PK DG S+I+
Sbjct: 12860 RIYALNKAGSSPPSKPTEYVTARM--PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKII 12917
Query: 966 GYFVQKADKKTMEWFNVYERNRHT---SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
GYFV+ +W T + L +Y FR +S P
Sbjct: 12918 GYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP-PSEPS 12976
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+ IL + D +A K L V AG + L+ V G P P V W
Sbjct: 12977 DPVTILAENVP------PRIDLSVAMKSLL-----TVKAGTNVCLDATVFGKPMPTVSWK 13025
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
K+ ++ + + + TL + + D+G YT A N G A KL+V
Sbjct: 13026 KDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13080
Score = 82.8 bits (203), Expect = 2e-15
Identities = 92/405 (22%), Positives = 156/405 (38%), Gaps = 35/405 (8%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+++V+ + T+ W PP G I Y+VE S W + + V R + L TG
Sbjct: 19191 IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS-QAVARTSIKIVRLTTG 19249
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT-------YIRKVGEQ 857
+ FRV N G+S + + V + P P+ + T + V +
Sbjct: 19250 SEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDG 19309
Query: 858 LNLVVPF--QGKPRPQVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSV 914
+ V+ + + K R ++W+K L +++ V D ++ R A + +G + S
Sbjct: 19310 GSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSK 19369
Query: 915 QIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
E + + PP V + + ++W P DG ++I GY V++ +
Sbjct: 19370 SCEP--------VPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERREL 19421
Query: 975 KTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
W Y + T V++L Y FRV+ N P S++T I+
Sbjct: 19422 PDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEP--SESTGPIIVKDDV 19479
Query: 1034 FKPFEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDP 1092
P + FR D +VV AG +N + G P P + W K+ +EI E
Sbjct: 19480 EPPRVMMDVKFR----------DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 19529
Query: 1093 KFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG--EALAECKL 1135
+ I + L ++ D G Y N G CK+
Sbjct: 19530 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574
Score = 77.8 bits (190), Expect = 5e-14
Identities = 95/402 (23%), Positives = 156/402 (38%), Gaps = 45/402 (11%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ +V+ TL W PP G I Y++E W + E ++ C L G
Sbjct: 14176 ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQG 14234
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP----KIRLPRHLRQT----YIRKVGE 856
+FRV VN G+ EP ++PV + + PP K + + T + R V +
Sbjct: 14235 NEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14293
Query: 857 QLNLVVPF--QGKPRPQVVWTKG-GAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + + + + + + W + P+ R V + + R +A + +G S
Sbjct: 14294 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14353
Query: 914 VQIEN--MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
++ MKD A GPP N V + +A + W P DG EI GY V+
Sbjct: 14354 EASDSVLMKDAAY-------PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14406
Query: 972 ADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILK 1029
W R T V DL +Y FR+ N G+ + P V + + +
Sbjct: 14407 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVER 14465
Query: 1030 TGITFKPFEYKEHDFRMAPKF-LTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKM 1086
MAP F L + R +V AG S + ++G P P+V W K+ +
Sbjct: 14466 ---------------EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14510
Query: 1087 EIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
++ + I N + L I + +D G + N G+
Sbjct: 14511 NLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGK 14550
Score = 77.4 bits (189), Expect = 7e-14
Identities = 77/267 (28%), Positives = 117/267 (43%), Gaps = 21/267 (7%)
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV----KDEKCFTELFVKEP 344
W K+G I+ S K+ F GK R L I L+D Y + K++ +L V+E
Sbjct: 4846 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905
Query: 345 PVLIVTPLEDQQVFV-GDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
PV V LE++ V G + ++ E+++E V+W KDG + + R G
Sbjct: 4906 PVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDGKIVVEK---PGRIVPGVIGLM 4961
Query: 404 HILIFSDVVQEDRGRYQV-ITNGGQCEAELIVEEKQLEVLQD-----IADLTVKASEQAV 457
L +D D G Y V + N E V K +EV++D I D VK A+
Sbjct: 4962 RALTINDADDTDAGTYTVTVENANNLECSSCV--KVVEVIRDWLVKPIRDQHVKPKGTAI 5019
Query: 458 FKCEVSDEKVTGKWYKNGVEV--RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
F C+++ + KW+K E+ P+ + I G L I + PED +Y +G
Sbjct: 5020 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG- 5078
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIH 542
AKL E +VE + E I+
Sbjct: 5079 -KRYPAKLTLGEREVELLKPIEDVTIY 5104
Score = 77.4 bits (189), Expect = 7e-14
Identities = 139/622 (22%), Positives = 222/622 (35%), Gaps = 82/622 (13%)
Query: 563 RLDVSITGEPPPVATWLKGDEVFTTTEGRTRI-----EKRVDCSSFVIESAQRED----- 612
RLDV T + V WLK D +G +RI E R S F +E+ +
Sbjct: 22246 RLDVVDTSKSSAVLAWLKPDH-----DGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22300
Query: 613 -------EGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITS------VGEDW 654
E + +K N G E +S+ ++ + + IT+ G +
Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22360
Query: 655 AILVWEPPMYDGGKP---VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
I V P+ G+P VT L E + K + R + T T + + + Y +
Sbjct: 22361 TIDV---PI--SGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 22415
Query: 712 RVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
+ N GV S+ P + P+ V V+ + L W P G I Y
Sbjct: 22416 TL--ENTAGVKTFSVTVVVIGRPGPVTGPIE--VSSVSAESCVLSWGEPKDGGGTEITNY 22471
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
+VE G+ W N+ V+R V +L FRV N G S+P A P+
Sbjct: 22472 IVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESA-PIIA 22529
Query: 832 REIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF------------QGKPRPQVVWTKGGA 879
PP P ++ + P+ + K R ++W K
Sbjct: 22530 EHPFVPPSA--PTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVK--- 22584
Query: 880 PLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINV 939
++V ++ V + Y L+ + A+ I P
Sbjct: 22585 ---ENKVPCLECNYKVTGLV-EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP 22640
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM---EWFNV-YERNRHTSCTVSD 995
V +V + + W AP DG S+++GY +++ + W Y TV+
Sbjct: 22641 EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTA 22700
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G+ Y FRV +N G+ +SK + TG EY + + L+
Sbjct: 22701 LSEGDTYEFRVLAKNAAGV-----ISKGSE---STGPVTCRDEYAPPKAELDARLHGDLV 22752
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ AG L+ AV G P+PK++W K E+ K + T I+ D+
Sbjct: 22753 --TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 22810
Query: 1116 GTYTCRAVNELGEALAECKLEV 1137
G YT N G ++V
Sbjct: 22811 GKYTLTVKNASGTKAVSVMVKV 22832
Score = 77.0 bits (188), Expect = 9e-14
Identities = 53/204 (25%), Positives = 88/204 (43%), Gaps = 16/204 (7%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++ E+ PP + + +V + + W+ P+ DG S I+GY V+ K + +W
Sbjct: 15738 VKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC-ATV 15796
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ T T++ LI G EY FRV +N G+SD R L + K D +
Sbjct: 15797 KVTEATITGLIQGEEYSFRVSAQNEKGISDP--------RQLSVPVIAK-------DLVI 15841
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P F V+AG ++ G P P V W K+ + +++ + + + L
Sbjct: 15842 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15901
Query: 1107 IRRPSPFDAGTYTCRAVNELGEAL 1130
I+ D G Y + N GEA+
Sbjct: 15902 IKDACREDVGHYVVKLTNSAGEAI 15925
Score = 74.7 bits (182), Expect = 5e-13
Identities = 97/436 (22%), Positives = 155/436 (35%), Gaps = 49/436 (11%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ A N+ G ++ K P P + + + L W PP G I Y+
Sbjct: 13063 ITAENSSGSKSATIKLKVLDKPGP---PASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119
Query: 773 VEYCLEGSEEWVPAN-TEPVERCGFTVKNLPTGARILFRVVGVNIAGR-----SEPATLA 826
V+ W + T P+ C +V+ L G FR+ N G +EPA
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSC--SVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAK 13177
Query: 827 QPVTIREIAEPPKIR--LPRHLRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLD 882
P +PP I H+ ++ + + + + + + V WTK ++
Sbjct: 13178 NPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VN 13233
Query: 883 TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMK--------DTATIRIRVVEKAG 934
+ RT ++ + EYE V N A G
Sbjct: 13234 RKPIIERT--------LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPG 13285
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEWFNVYERNRHTSCT 992
PP V + ++ + W P DG S I+GY V+ +AD N+ + + T
Sbjct: 13286 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFE 13345
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
V+ L+ +Y FRVY N G SD V + I P + D R
Sbjct: 13346 VTGLMEDTQYQFRVYAVNKIGYSDPSDVPD---KHYPKDILIPPEGELDADLRKT----- 13397
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
++ AG + L V+G P PK+ W K + +R+ I + L +
Sbjct: 13398 ----LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 13453
Query: 1113 FDAGTYTCRAVNELGE 1128
+DAG Y N G+
Sbjct: 13454 YDAGKYILTLENSCGK 13469
Score = 73.6 bits (179), Expect = 1e-12
Identities = 105/414 (25%), Positives = 152/414 (36%), Gaps = 56/414 (13%)
Query: 742 HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNL 801
+L + DV+ T+ W PP G I Y++E C W + V G TV L
Sbjct: 11997 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRL 12055
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G +FRV N G P T ++PV + + P P + KV ++ V
Sbjct: 12056 IEGNEYIFRVRAENKIGTGPP-TESKPVIAKTKYDKPGRPDPPE-----VTKVSKEEMTV 12109
Query: 862 V----PFQG-----------KPRPQVVWT---KGGAPLDTSRVHVRTSDFDTVFFVRQAA 903
V + G K + W K P +V D + F V+
Sbjct: 12110 VWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAEN 12169
Query: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
GE L + KD +E GPP N V + + + W P DG +
Sbjct: 12170 EIGIGEPSLPSRPVVAKDP-------IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12222
Query: 964 IMGYFVQK----ADKKTMEWF---NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
I+GY V+ AD E + N + TV+ L EY FRV +N G+
Sbjct: 12223 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12282
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
+ + KP E E + L+ +V AG L VRG P
Sbjct: 12283 PAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGRPA 12330
Query: 1077 PKVVWMKNKME--IREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
PKV W K ++ +R+ L+ ++ N R D+G Y+ VN GE
Sbjct: 12331 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRD---DSGKYSLTLVNPAGE 12381
Score = 73.6 bits (179), Expect = 1e-12
Identities = 101/421 (23%), Positives = 155/421 (36%), Gaps = 60/421 (14%)
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLP 802
L V VT L W PP + G I Y++E W +TE V+ + V L
Sbjct: 18504 LKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE-VQALNYKVTKLL 18562
Query: 803 TGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP--------KIRLPRHLRQTYIRKV 854
G +FRV+ VN G EP + PVT +PP + T+ R V
Sbjct: 18563 PGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPV 18621
Query: 855 GEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ + + + + + V WTK T +R ++ YE
Sbjct: 18622 DDGGTEIEGYILEKRDKEGVRWTKCNKKTLTD------------LRLRVTGLTEGHSYEF 18669
Query: 913 SVQIENMKDTA-----TIRIRVVEKA---GPPINVMVKEVWGTNALVEWQAPKDDGNSEI 964
V EN ++ R + GPP N V + ++ + W P DG + +
Sbjct: 18670 RVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPV 18729
Query: 965 MGYFVQKADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDS---PG 1019
GY V+ + EW + TV+ L EY FR+ N G+ + PG
Sbjct: 18730 KGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPG 18789
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC--AVRGHPKP 1077
RI I + D R +VVV SA L ++G P+P
Sbjct: 18790 SVVAQERIEPPEIEL------DADLR-----------KVVVLRASATLRLFVTIKGRPEP 18832
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTL-NIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
+V W K + + + + +T+ +L + N+ R FD+G Y N G A +
Sbjct: 18833 EVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR---FDSGRYNLTLENNSGSKTAFVNVR 18889
Query: 1137 V 1137
V
Sbjct: 18890 V 18890
Score = 70.1 bits (170), Expect = 1e-11
Identities = 61/232 (26%), Positives = 96/232 (41%), Gaps = 25/232 (10%)
Query: 905 SDSGEYELSVQIENM-----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
S+ EY V EN T ++ E PP ++ + ++ + + W PK D
Sbjct: 14627 SEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHD 14686
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
G S+I GY ++ K + +W ++ + C V +L G EY F+V N G S +P
Sbjct: 14687 GGSKITGYVIEAQRKGSDQWTHI-TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS-APR 14744
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTPLIDRVVVA--GYSAALNCAVRGHPK 1076
S+ P KE M P+ L + ++V+A G + + V G PK
Sbjct: 14745 ESR-------------PVIVKEQT--MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPK 14789
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
P V W K +++ + LNI D+G Y A N +GE
Sbjct: 14790 PTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 14841
Score = 69.7 bits (169), Expect = 1e-11
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 31/279 (11%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K E+R + I ++ F LV+D+V D G YT + S K F+ ++
Sbjct: 16670 KWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLEN---SSGTKSAFVTVR 16724
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V P P ++L + T ++ VSIT EPP + K
Sbjct: 16725 VLDTPS---PPVNLKVTEITKDS-------------VSITWEPPLLDGGSKIKNYIVEKR 16768
Query: 590 GRTR-----IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF---LQVVDVPDP 641
TR + +S+ I+ Q + + N G + + ++V +VP P
Sbjct: 16769 EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQP 16828
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
P + + V + L W P +DGG + Y+VE + K S++W + + T
Sbjct: 16829 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVI--T 16886
Query: 702 KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP 740
+ +G Y RV AVN G S P P + EP
Sbjct: 16887 NLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 16925
Score = 69.3 bits (168), Expect = 2e-11
Identities = 81/305 (26%), Positives = 128/305 (41%), Gaps = 40/305 (13%)
Query: 429 EAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISH 488
E EL + +++ VL+ A L + + + + EV EK G + R I
Sbjct: 18801 EIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL---------TDRAQIEV 18851
Query: 489 VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
F LVID+V D G Y + + +K F+ ++V LD
Sbjct: 18852 TSSFTMLVIDNVTRFDSGRYNLTLEN---NSGSKTAFVNVRV------------LD---- 18892
Query: 549 TSENAIVVVAGNKLRLD-VSITGEPPPVATWLK-----GDEVFTTTEGRTRIEKRVDCSS 602
S +A V + +++ D V+++ EPP + K ++ TT + I ++
Sbjct: 18893 -SPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT 18951
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVW 659
F IE+ Q + + +N G + + + V V P PP V + V + A + W
Sbjct: 18952 FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 19011
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
E P DGG +TGY+VE + KGS++W E T + G Y RV AVN
Sbjct: 19012 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISG--LTAGEEYVFRVAAVNEK 19069
Query: 720 GVSQP 724
G S P
Sbjct: 19070 GRSDP 19074
Score = 68.2 bits (165), Expect = 4e-11
Identities = 79/289 (27%), Positives = 122/289 (42%), Gaps = 32/289 (11%)
Query: 340 FVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKK 399
FVKE +I+T E FVG VS A WMKDG + ++RF
Sbjct: 4812 FVKEIKDIILTESE----FVGSSAIFECLVSPSTAITTWMKDGSNIRE----SPKHRFIA 4863
Query: 400 DGKRHILIFSDVVQEDRGRYQVITNGGQCE----AELIVEEKQLEVLQDI-ADLTVKASE 454
DGK L DV D G Y + G E A+L+VEE + ++ + ++TV +
Sbjct: 4864 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ 4923
Query: 455 QAVFKCEVSDEKVTGKWYKNG-VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VP 512
CE++ E+ W K+G + V RI +G L I+D D G YT V
Sbjct: 4924 PLYLSCELNKERDV-VWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 4982
Query: 513 DGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEP 572
+ L S+ + +E+ +++ K P + D K AI D++ +
Sbjct: 4983 NANNLECSSCVKVVEVIRDWLVK--PIR---DQHVKPKGTAI-------FACDIA---KD 5027
Query: 573 PPVATWLKG-DEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
P W KG DE+ +T I + + I++A ED Y +++
Sbjct: 5028 TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 5076
Score = 68.2 bits (165), Expect = 4e-11
Identities = 106/473 (22%), Positives = 165/473 (34%), Gaps = 51/473 (10%)
Query: 679 KKGSQ---RWMKLNFEVF-TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPI 734
KKG Q + ++NFE T T + + + A N +G + +
Sbjct: 14795 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP 14854
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
P + P+ ++V+ T W PP G I Y+VE S WV T + R
Sbjct: 14855 GPPTGPIKF--DEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 14911
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV 854
+ L TG FRV N G T A V P P+ T + K
Sbjct: 14912 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQ---VTAVTKD 14968
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF------------VRQA 902
++ P + GG+P+ HV + + + + + +
Sbjct: 14969 SMTISWHEPL----------SDGGSPI--LGYHVERKERNGILWQTVSKALVPGNIFKSS 15016
Query: 903 ARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPK 957
+D YE V ENM + + + ++ PP + + ++W P+
Sbjct: 15017 GLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPE 15076
Query: 958 DDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
G +I Y V+K D W N TVS L Y FRV +N G
Sbjct: 15077 YTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAIS 15136
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
P + IT + + + ++ KF +I + AG + L V G P
Sbjct: 15137 PPSEPSDA-------ITCRD-DVEAPKIKVDVKFKDTVI---LKAGEAFRLEADVSGRPP 15185
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
P + W K+ E+ K I L + + D+G YT A N G A
Sbjct: 15186 PTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 15238
Score = 67.0 bits (162), Expect = 1e-10
Identities = 58/205 (28%), Positives = 84/205 (40%), Gaps = 19/205 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT-SCTVS 994
P ++ VKEV + W PK DG SEI+ Y ++ T ++ V N + TV
Sbjct: 10415 PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVK 10474
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL-TP 1053
L G+ Y +RV NI G K KP K+ +AP L
Sbjct: 10475 GLKEGDTYEYRVSAVNIVGQG-------------KPSFCTKPITCKDE---LAPPTLHLD 10518
Query: 1054 LIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
D++ + G + AL G PKPKV W K++ ++ ED + I L L +
Sbjct: 10519 FRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKR 10578
Query: 1113 FDAGTYTCRAVNELGEALAECKLEV 1137
D+G Y N G C++ V
Sbjct: 10579 SDSGKYCVVVENSTGSRKGFCQVNV 10603
Score = 65.9 bits (159), Expect = 2e-10
Identities = 242/1196 (20%), Positives = 419/1196 (35%), Gaps = 189/1196 (15%)
Query: 41 EDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKS 100
E+Q+ E F+ KP + G V +V G KP + W K G
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP---KPHVYWKKS-----GVPL 1076
Query: 101 GARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDA 160
+ +K S+N + +L I D G Y + V+ K S ++ EA +
Sbjct: 1077 TTGYRYKVSYNKQTG--ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL 1134
Query: 161 SGQSLESFKRTS-------EKKSDTAGELDFSGLLKKREVVEEE-KKKKKKDDDDLGIPP 212
E +T K +TA +S K+ E + +KK KD +
Sbjct: 1135 MKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYV 1194
Query: 213 EIWEL-LKGAKKSEYEKIAFQYGITDLRGMLKR--LKKAKVEVKKSAAFTKKLDPA---Y 266
E E + ++ ++I ++ T L +L+ +K V++ +S A D Y
Sbjct: 1195 EDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNY 1254
Query: 267 QVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRI-LTINKCTLADDA 324
++ G + ++S L + W+K+G+ IK +Y + + R L I D+
Sbjct: 1255 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314
Query: 325 AYEVAVKDEK----CFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMK 380
Y + K C +L+V EP + P + R+ S + +
Sbjct: 1315 IYTAFASNIKGNAICSGKLYV-EPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSP 1373
Query: 381 DGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE 440
+ R + G+R ++E +E QLE
Sbjct: 1374 ARMSPARMSPARMSPARMSPGRR--------LEE-------------------TDESQLE 1406
Query: 441 VLQDIADLTVKASEQAVFKCEVS-----DEKVTGK------WYKNGVEVRP--SKRITIS 487
L V + FKC D KV G+ W+ +G ++ + ++ I
Sbjct: 1407 RLYK----PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIK 1462
Query: 488 HVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSG 547
G L+I P D G++T V A S + + VE V Q P
Sbjct: 1463 EDGT-QSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---LTVEAVEHQVKPMFVEKLKN 1518
Query: 548 KTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE-GRTRIEKRVDCSSFVIE 606
+ + G++L + V TG P P WLK ++ + + RIE ++ I+
Sbjct: 1519 ------VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1572
Query: 607 SAQREDEGRYTIKVTNPVGEDVASIFLQV-VDVPDP-PEAVRITSVGEDWAILVWEPPMY 664
S +D YT N G D + V V+ +P PE I G A + P +
Sbjct: 1573 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPEL- 1631
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
+P+ + G ++W EG LY+
Sbjct: 1632 ---EPL------HLRYGQEQWE------------------EGDLYDKEKQQKPFFKKKLT 1664
Query: 725 SMNTKPFMP------IAPTSEPLHLI--VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
S+ K F P + P +P ++ + D + R N G +D Y V Y
Sbjct: 1665 SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD-YGVAYS 1723
Query: 777 LE------------GSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
+ G++ E+ LP G + L R+ + E A
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH-EGAL 1782
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS 884
+E +P + P +R GE G P+P+V W G + S
Sbjct: 1783 TGVTTDQKEKQKPDIVLYPEPVRVL----EGETARFRCRVTGYPQPKVNWYLNGQLIRKS 1838
Query: 885 R--------VH----VRTSDFDTVFFVRQAARSDSG--EYELSVQIENMKDTATIRIRV- 929
+ +H V +DT V+ A + G E+++ ++I+ +D ++ R
Sbjct: 1839 KRFRVRYDGIHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1897
Query: 930 -----------------VEKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V+K P++ V ++ + + P++ + E+ F
Sbjct: 1898 EPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE--SEELRSKF 1955
Query: 969 VQKADKKTMEWFNVYE-RNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
++ ++ E E ++R + +L+ + +T+ + + K A
Sbjct: 1956 KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKEL-----TEEEKKALAEE 2010
Query: 1028 LKTGI-TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
K I TFKP + + APK + + V G A V G P P+ W KN +
Sbjct: 2011 GKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGV 2070
Query: 1087 EI-REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+I R D + V L IR + D+ + +A+N GE + L V+ Q
Sbjct: 2071 KIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 65.9 bits (159), Expect = 2e-10
Identities = 133/651 (20%), Positives = 240/651 (36%), Gaps = 106/651 (16%)
Query: 33 EAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGK 92
E P+ P+ + P P + D+V+ E G+ A +V+G +L + W+
Sbjct: 3283 EVPEVVSPDQEMPVY--PPAIITPLQDTVTSE-GQPARFQCRVSGTDLK----VSWYSKD 3335
Query: 93 WLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVK--AKDTCDSCGFN 150
S+ F++ T +L I + D G Y + +
Sbjct: 3336 KKIKPSRFFRMTQFED---------TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 3386
Query: 151 IDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGI 210
++V+A + +SG+ + KS + F+ K E +K+ K
Sbjct: 3387 LEVQALDRQSSGKDVRE-----SAKSQAVADSSFT----KEESKISQKEIKSFQGSSYEY 3437
Query: 211 PPEIWELLKGAKKSEYEKIAFQ----YGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAY 266
+++E + ++ S + + Q L + + + +K K+S K+
Sbjct: 3438 EVQVFESV--SQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGEAPKIFLHL 3495
Query: 267 Q---VDRGNKIKLMVEISDPD-LTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLAD 322
Q V G+ + + + D + + W G +I+ S + G + LTI L D
Sbjct: 3496 QDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVD 3555
Query: 323 DAAYEVAVKDE----KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA------VEVSEE 372
Y V ++ L V+ P I+ +Q++ +EM + EE
Sbjct: 3556 QGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEI----EMEMKEFSSSFLSAEEE 3611
Query: 373 GA-----QVMWMKDGVELTREDS-FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
G Q+ + + +EL E + ++ +K+G I I +V D I+ G
Sbjct: 3612 GLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFI-KEVSNAD------ISMG- 3663
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
D+A L+V + K +W+ NGV + PS
Sbjct: 3664 -----------------DVATLSVTV---------IGIPKPKIQWFFNGVLLTPSADYKF 3697
Query: 487 SHVGRFHKLVIDDVRPEDEGDYT-FVPDGYALSLSA---KLN-----FLEIKVEYVPKQE 537
G H L+I + EDEG+YT + Y ++ + K+N + + E +
Sbjct: 3698 VFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKS 3757
Query: 538 PPKIHLDCSGKTSENA--IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
K+ C + I G + ++ GEP P TW K ++ T+ T I
Sbjct: 3758 LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIH 3817
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS----IFLQVVDVPDPP 642
+F++ QRED G Y K N +GE + + L+ D+ D P
Sbjct: 3818 NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3868
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 17/203 (8%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
I E+ PP + V + ++A++ W P DG S I GY ++ K + W
Sbjct: 22235 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 22293
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ + TV L+ EY FRV +N G S+ F KE
Sbjct: 22294 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREA-------------FSSVIIKEPQIEP 22340
Query: 1047 APKFLTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104
LT + ++++ AG ++ + G P PKV W +M ++E + IT + T
Sbjct: 22341 TAD-LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTT 22399
Query: 1105 LNIRRPSPFDAGTYTCRAVNELG 1127
L ++ D+G Y N G
Sbjct: 22400 LTVKDSMRGDSGRYFLTLENTAG 22422
Score = 65.5 bits (158), Expect = 3e-10
Identities = 33/94 (35%), Positives = 46/94 (48%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P ++ L + V+ G S L C + G+P P V W + +I F IT G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
R D+G +TC AVNE G C L V+V +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 990
Score = 65.5 bits (158), Expect = 3e-10
Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 18/219 (8%)
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
T + I +++ G P N+ + + T ++W+ P DG S + Y V++ K + +W
Sbjct: 11785 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 11844
Query: 982 VYERNRHTSCTVSDLIVGNEYY-FRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYK 1040
V++ + + + D V N+ Y FRV T+N G SD K ++K + + K
Sbjct: 11845 VHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWV---KTEEVVVKEDLQKPVLDLK 11901
Query: 1041 EHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK--MEIREDPKFLITN 1098
L+ ++ V AG + L VRG P P+V W K+K ++ P+ I
Sbjct: 11902 ----------LSGVL--TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDT 11949
Query: 1099 YQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + D G Y A N G +A + V
Sbjct: 11950 RADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 65.1 bits (157), Expect = 4e-10
Identities = 75/317 (23%), Positives = 124/317 (39%), Gaps = 50/317 (15%)
Query: 269 DRGNKIKLMVEISDPDLTLK--WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G +K + +I + D + + W+ ++++ S KY IL + T DD Y
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25334
Query: 327 EVAV----KDEKCFTELFVK---------------------------EPPVLIVTPLEDQ 355
V ++ + ELFVK E P PL ++
Sbjct: 25335 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25394
Query: 356 QVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQE 414
+VG+ V V ++ V W K G ++ D+ K +Y F+ D + L + V +
Sbjct: 25395 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFESDKGLYQLTINSVTTD 25453
Query: 415 DRGRYQVITNG----GQCEAELIV------EEKQLEVL--QDIADLTVKASEQAVFKCEV 462
D Y V+ C+A+L V + L + + +A+ + + F+ V
Sbjct: 25454 DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRV 25513
Query: 463 SD-EKVTGKWYKNGVEVRPSKRITISHVG-RFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
S T KW K+G + I I H G ++ L I D PED G Y A S S
Sbjct: 25514 SGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTS 25573
Query: 521 AKLNFLEIKVEYVPKQE 537
+ + ++ Y KQE
Sbjct: 25574 CQAHLQVERLRY-KKQE 25589
Score = 60.5 bits (145), Expect = 9e-09
Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 19/196 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYE-RNRHTSCTVS 994
P + V +V + + W+ P DG S + GY ++ T W V + TV+
Sbjct: 23333 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23392
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTP 1053
L G +Y FR+ +N G+S+ R T +T + D R+ P L+
Sbjct: 23393 SLNEGEQYLFRIRAQNEKGVSEP--------RETVTAVTVQ-------DLRVLPTIDLST 23437
Query: 1054 LIDRV--VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
+ + V AG L + G P P W ++RE + + + V L IR +
Sbjct: 23438 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETT 23497
Query: 1112 PFDAGTYTCRAVNELG 1127
D G YT N G
Sbjct: 23498 IRDTGEYTLELKNVTG 23513
Score = 59.7 bits (143), Expect = 2e-08
Identities = 69/295 (23%), Positives = 117/295 (39%), Gaps = 27/295 (9%)
Query: 348 IVTPLEDQQVFVGDRVEMAVEV-SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
I + +V G + V S+ A+V W +GVEL ++S K Y G +
Sbjct: 26071 ITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESSKIHYT-NTSGVLTLE 26127
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
I D +D G Y+ + + EA D A L V + + + DE+
Sbjct: 26128 IL-DCHTDDSGTYRAVCTNYKGEAS------------DYATLDVTGGDYTTYASQRRDEE 26174
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDG---YALSLSAKL 523
V + E+ ++ +S + ++ E + T + Y S SA++
Sbjct: 26175 VPRSVFP---ELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEM 26231
Query: 524 NFLEIKVEYVP-KQEPPKIHLDCSGK--TSENAIVVVAGNKLRLDVSITGEPPPVATWLK 580
++ + + K KI + + T ++ V G R GEP P TWL+
Sbjct: 26232 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26291
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
+V +T+ R ++ S+F I S Q DEG Y++ V N G+ A L +
Sbjct: 26292 KGQVLSTS-ARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26345
Score = 59.3 bits (142), Expect = 2e-08
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 31/222 (13%)
Query: 439 LEVLQDIADLTVKASE----QAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHK 494
L+ +++I D+ + SE A+F+C VS W K+G +R S + G+ K
Sbjct: 4810 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869
Query: 495 LVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAI 554
L I DV+ D G+YT V L K + ++ VE +P + KT E +
Sbjct: 4870 LHIIDVQLSDAGEYTCV---LRLGNKEKTSTAKLVVEELPVR---------FVKTLEEEV 4917
Query: 555 VVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 614
VV G L L + E V W K ++ GR + I A D G
Sbjct: 4918 TVVKGQPLYLSCELNKERDVV--WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAG 4975
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
YT+ V N + +S V++ V DW +
Sbjct: 4976 TYTVTVENANNLECSS-------------CVKVVEVIRDWLV 5004
Score = 59.3 bits (142), Expect = 2e-08
Identities = 118/608 (19%), Positives = 216/608 (35%), Gaps = 90/608 (14%)
Query: 6 PAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPT------GVFLKKPD 59
P K+P+ P+ EA ++P+ + P+ SPT +PT + + P
Sbjct: 26358 PPRVKSPE----PRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPP 26413
Query: 60 SVS----VETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGARFSFKESHNSAS 114
++ E K+ + V + + W+K GK L K F F H SA
Sbjct: 26414 KITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL----KENGHFQF---HYSAD 26466
Query: 115 NVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEA-----PRQDASGQSLESFK 169
Y EL I + D+G Y E+ + +A + ++ +S +
Sbjct: 26467 GTY--ELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQ 26524
Query: 170 RTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLG----------IPPEIWELLK 219
+T+E E + + V+ + D + P IW
Sbjct: 26525 KTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIW---- 26580
Query: 220 GAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKL-DPAYQVDRGNKIKLMV 278
K + +Y +++ +G L+ K + S +T + + A V K+ +
Sbjct: 26581 -TKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26638
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
I D + + EI P K V + ++ L + +++ + E E+
Sbjct: 26639 -IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 26697
Query: 339 LFVKEPPVLIVTPLE---------------------------DQQVFVGDRVEMAVEVSE 371
L +E T LE Q+ + + + ++ +
Sbjct: 26698 LISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANI 26757
Query: 372 EGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI--TNGG-- 426
GA V W+ +GVELT + YR+ G L D G I T G
Sbjct: 26758 AGATDVKWVLNGVELTNSE----EYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIV 26813
Query: 427 QCEAELIVEEKQLEV---LQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSK 482
+C+ +L + ++ + + + + +F CE+S E +W+KN + + S
Sbjct: 26814 KCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISS 26873
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
++IS + L I + D G YT + SA + + + + P +E +
Sbjct: 26874 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSRE---VV 26930
Query: 543 LDCSGKTS 550
L SG TS
Sbjct: 26931 LRTSGDTS 26938
Score = 56.6 bits (135), Expect = 1e-07
Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 605 IESAQREDEGRYTIKVTNPVGEDVAS------IFLQVVDVPDPPEAVRITSVGEDWAILV 658
+++ + E ++ +K N +G S + ++ P PP R+ + L
Sbjct: 12152 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 12211
Query: 659 WEPPMYDGGKPVTGYLVERKKK-----GSQRWMKLNFEV-FTETTYESTKMIEGILYEMR 712
W P+YDGG P+ GY+VE + K + W + N + T + E YE R
Sbjct: 12212 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 12271
Query: 713 VFAVNAIGVSQPS 725
V A N +G+ +P+
Sbjct: 12272 VCAQNQVGIGRPA 12284
Score = 56.2 bits (134), Expect = 2e-07
Identities = 50/208 (24%), Positives = 85/208 (40%), Gaps = 25/208 (12%)
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ-KADKKTMEWFNVYERNRHTSCTV 993
PP + V E+ +A + W P DG ++I GY + +++ + + Y + S V
Sbjct: 12496 PPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVV 12555
Query: 994 SDLIVGNEYYFRVYTENICGLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF 1050
+ L G +Y FRV N G+S ++ GV Y+ + + PK
Sbjct: 12556 TGLKEGKKYKFRVAARNAVGVSLPREAEGV------------------YEAKEQLLPPKI 12597
Query: 1051 LTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
L P +++ + AG + V G P P W K + E+ + L I+
Sbjct: 12598 LMP--EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 12655
Query: 1110 PSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D+G Y+ A N G + K+ V
Sbjct: 12656 VTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 55.1 bits (131), Expect = 4e-07
Identities = 53/239 (22%), Positives = 92/239 (38%), Gaps = 24/239 (10%)
Query: 907 SGEYELSVQIENMKDTATIRIR-----VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGN 961
S E E S ++ AT++I+ ++++ GP I+ + + +
Sbjct: 4402 SEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA 4461
Query: 962 SEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVS 1021
E+ YF K ++ + ++N +T V D + ++ E +C + G +
Sbjct: 4462 KEVNWYFENKLVPSDEKFKCLQDQNTYT--LVIDKVNTEDHQ----GEYVCEALNDSGKT 4515
Query: 1022 KNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVW 1081
+A++ R AP + V G+ A C ++ P + W
Sbjct: 4516 ATSAKLTVVK-------------RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 4562
Query: 1082 MKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
K EI E K I + + + +L I R D G YTC+A NE G L V VP
Sbjct: 4563 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4621
Score = 55.1 bits (131), Expect = 4e-07
Identities = 59/225 (26%), Positives = 87/225 (38%), Gaps = 30/225 (13%)
Query: 927 IRVVEKAGPPIN---VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
I V+ GPP + + E + ++W+ P+ +G S I GY ++K ++ V
Sbjct: 8981 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 9040
Query: 984 ERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+R TS V +L Y FRV N G S+ P + P
Sbjct: 9041 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE-PSL---------------PLNVVIQ 9084
Query: 1043 DFRMAPKFLTPLIDR----VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL--- 1095
D + P L R V AG + V G P PK+ W KN+ I + L
Sbjct: 9085 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 9144
Query: 1096 ---ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + L+I + D GTYT A N LG +EV
Sbjct: 9145 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9189
Score = 55.1 bits (131), Expect = 4e-07
Identities = 72/327 (22%), Positives = 125/327 (38%), Gaps = 24/327 (7%)
Query: 518 SLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVAT 577
+L + + EI PK + P I + N V N L +TG P P+
Sbjct: 24598 NLGGESEWSEISEPITPKSDVP-IQAPHFKEELRNLNVRYQSNAT-LVCKVTGHPKPIVK 24655
Query: 578 WLKGDEVFTTTEGRTRIEK-RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV- 635
W + + + RI++ + +I S +D Y ++ TN G + L+V
Sbjct: 24656 WYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Query: 636 ----VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE 691
+ +P E + + + P GKP ++ +K +++
Sbjct: 24716 VPAKIHLPKTLEGMGAVHALRGEVVSIKIP---FSGKPDP--VITWQKGQDLIDNNGHYQ 24770
Query: 692 VFTETTYESTKMIEGILYEMRVFAV----NAIGVSQPSMNTKPFMPIAPTSEPLHLI-VE 746
V ++ S G+ + F V N G+ Q ++ + +A +P + V
Sbjct: 24771 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE----LDVADVPDPPRGVKVS 24826
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
DV+ + L W P G I Y+VE C +E W+ R +TV NL
Sbjct: 24827 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR--YTVINLFGKTS 24884
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIRE 833
FRV+ N G S+P+ ++P +E
Sbjct: 24885 YQFRVIAENKFGLSKPSEPSEPTITKE 24911
Score = 51.2 bits (121), Expect = 5e-06
Identities = 68/310 (21%), Positives = 115/310 (37%), Gaps = 56/310 (18%)
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ--VITN 424
+E ++ QV W +L + ++ Y +DG IL D+ + D G Y+ V+ +
Sbjct: 25286 IENYDQSTQVTWYFGVRQLENSEKYEITY---EDGVA-ILYVKDITKLDDGTYRCKVVND 25341
Query: 425 GGQCE--AELIVE---------------------------EKQLEVLQDIADLTVKASEQ 455
G+ AEL V+ E+ E + + T E
Sbjct: 25342 YGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN 25401
Query: 456 AVFKCEVS---DEKVTGKWYKNGVEVRPS---KRITISHVGRFHKLVIDDVRPEDEGDYT 509
F ++ + VT WYK+G +++P K+ T ++L I+ V +D+ +YT
Sbjct: 25402 VRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 25459
Query: 510 FVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA----GNKLRLD 565
V S K V PP D + + ++ A G + +
Sbjct: 25460 VVARNKYGEDSCKAKLT------VTLHPPPT---DSTLRPMFKRLLANAECQEGQSVCFE 25510
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 625
+ ++G PPP W K + + I + +D + I ED G Y + TN G
Sbjct: 25511 IRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25570
Query: 626 EDVASIFLQV 635
LQV
Sbjct: 25571 STSCQAHLQV 25580
Score = 49.3 bits (116), Expect = 2e-05
Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 17/204 (8%)
Query: 443 QDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKR--ITISHVGRFHKLVIDD 499
Q + + V A F+ +S V W+++G + S + IS KL I
Sbjct: 10 QPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPA 69
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V + G Y+ + ++ L +K E P ++ ++ V G
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELL-VKAETAPPNFVQRLQ----------SMTVRQG 118
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+++RL V +TG P PV + + G E+ ++ + +I + D S +I A ED G Y++
Sbjct: 119 SQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 619 KVTNPVGEDVASIFLQVVDVPDPP 642
TN VG ++ L V + P
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVP 200
Score = 49.3 bits (116), Expect = 2e-05
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P +TPL D V G A C V G KV W +I+ F +T ++ L I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
P D GTYT A N +G+ + L + V
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEV 3389
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Query: 351 PLEDQQVFVGDRVEMAVEVSEEGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFS 409
PL+ V G +S +V W +DG ++ + F DG+ + I +
Sbjct: 11 PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRAKLTIPA 69
Query: 410 DVVQEDRGRYQV-ITNG-GQCE--AELIVEEKQL--EVLQDIADLTVKASEQAVFKCEVS 463
V + + GRY + TNG GQ AEL+V+ + +Q + +TV+ Q + V+
Sbjct: 70 -VTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 464 DEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
K+Y++G E++ S IS G + L+I + PED G Y+
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/94 (30%), Positives = 40/94 (42%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P+ L L V +G A + G P+PK+ W K + + K + TL +
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P DA YTC A N+ G A L V VP+
Sbjct: 3253 IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR---EDPKFLITNYQGVLT 1104
P+F PL ++ G + + HP+P V W K+ +I+ D K+ + +G+
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L I + D YT A N+ GE + KL V
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 48.5 bits (114), Expect = 4e-05
Identities = 76/332 (22%), Positives = 117/332 (35%), Gaps = 51/332 (15%)
Query: 243 KRLKKAKVEVKKSAAFTKKLDP-------AYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQ 294
++ + K EV FT P +++V G + ++ + S P +KW+ NG
Sbjct: 26048 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26107
Query: 295 EIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLED 354
E++ SSK + N L I C D Y + K + L VT
Sbjct: 26108 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYA----TLDVTG--- 26160
Query: 355 QQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGK-------RHILI 407
GD A + +E ELTR +++ A FKK + R +
Sbjct: 26161 -----GDYTTYASQRRDEEVPRSVFP---ELTRTEAY-AVSSFKKTSEMEASSSVREVKS 26211
Query: 408 FSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE---------------VLQDIADLTVKA 452
+E Y+ + A L EEK LE +L +TV
Sbjct: 26212 QMTETRESLSSYEHSASAEMKSAAL--EEKSLEEKSTTRKIKTTLAARILTKPRSMTVYE 26269
Query: 453 SEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
E A F C+ E V T W + G + S R ++ I V+ DEG+Y+ V
Sbjct: 26270 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVV 26329
Query: 512 PDGYALSLSAKLNFLEIKVEYVPK--QEPPKI 541
+ A+ K K PP++
Sbjct: 26330 VENSEGKQEAEFTLTIQKARVTEKAVTSPPRV 26361
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/91 (32%), Positives = 40/91 (43%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
AP+ + V G + V+ P +V W N +E++E K TN GVLTL
Sbjct: 26068 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 26127
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
I D+GTY N GEA L+V
Sbjct: 26128 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 46.2 bits (108), Expect = 2e-04
Identities = 47/176 (26%), Positives = 78/176 (44%), Gaps = 12/176 (6%)
Query: 341 VKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKD 400
+KE +I TPL D GD V + ++ +V W + + ++ FK +D
Sbjct: 4430 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLVPSDEKFKCL----QD 4484
Query: 401 GKRHILIFSDVVQED-RGRY--QVITNGGQC--EAELIVEEKQLEVLQ-DIADLTVKASE 454
+ L+ V ED +G Y + + + G+ A+L V ++ V++ I L V
Sbjct: 4485 QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGH 4544
Query: 455 QAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
A F CE+ S V +W+K G E+ S + +I L I + D G+YT
Sbjct: 4545 LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4600
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1032 ITFKPFEYKEHDFRMAP--KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR 1089
+T K F+ + F P +F PL D+ V G +A L C V KV W KN EI
Sbjct: 5962 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEIL 6020
Query: 1090 EDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
+ K+ I V L I +P D TYTC A
Sbjct: 6021 KSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 6053
Score = 44.7 bits (104), Expect = 5e-04
Identities = 48/210 (22%), Positives = 76/210 (36%), Gaps = 28/210 (13%)
Query: 457 VFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGY 515
V K E D+ WY ++ S++ I++ L + D+ D+G Y V + Y
Sbjct: 25283 VCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDY 25342
Query: 516 ALSLSAKLNFL----EIKVEYVPK---------------QEPPKIHLDCSGKTSENAIVV 556
S F+ E+ Y + + PP+ L KT+
Sbjct: 25343 GEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA------ 25396
Query: 557 VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSF--VIESAQREDEG 614
G +R V+IT P P TW K + + + D + I S +D+
Sbjct: 25397 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 25456
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEA 644
YT+ N GED L V P P ++
Sbjct: 25457 EYTVVARNKYGEDSCKAKLTVTLHPPPTDS 25486
Score = 44.3 bits (103), Expect = 7e-04
Identities = 28/91 (30%), Positives = 42/91 (46%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P F+ L V G L V G P P V + ++ EI+ F I+ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
P D+GTY+ A N +G A + +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 1/91 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF-LITNYQGVLTLN 1106
P FL L G A V G P P V W K ++ + +I N G T
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ P D+G Y C+A N LGE+ +L V
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED--PKFLITNYQGVLT 1104
AP F PL VV+ G +A + G P P+V W ++ I P I+ G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L I + ++G Y+ +A N G+A + +L V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/170 (22%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
++VV+ G+ + I+G P P +W + G + T+T +I + I + +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
+ GRY++K TN G+ ++ L V PP V+ ++ V + VT
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-----SMTVRQGSQVRLQVRVT 128
Query: 672 GY---LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
G +V+ + G++ L+F++ E S + E + ++VNA
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNA 178
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/285 (21%), Positives = 104/285 (36%), Gaps = 41/285 (14%)
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDR-----GRYQVITNGGQCEAELIVEEKQLEVLQ 443
D++K+ + + + I V+E+R GR +T + A + + ++
Sbjct: 842 DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVS 901
Query: 444 DIADLTVKASEQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRP 502
+ ++TV E +C +S T WY+ ++ S I+ +L+I +
Sbjct: 902 GLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFA 961
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKV-EYVPKQ----------------EPPKIHLDC 545
ED G +T A ++S +L ++V E K+ E + +
Sbjct: 962 EDSGRFTCSAVNEAGTVSTSC-YLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1020
Query: 546 SGKTSENA--------------IV--VVAGNKLRLDVSITGEPPPVATWLKGDEVFTT-T 588
+ T E A +V +V G + + G P P W K TT
Sbjct: 1021 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGY 1080
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
+ K+ VI +D G YTI V N GE AS L
Sbjct: 1081 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 40.4 bits (93), Expect = 0.010
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
+ V+ G + L+ I+G P P TW + D ++ ++ + + + + + +I A ED
Sbjct: 906 VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLMIREAFAED 963
Query: 613 EGRYTIKVTNPVGEDVASIFLQV 635
GR+T N G S +L V
Sbjct: 964 SGRFTCSAVNEAGTVSTSCYLAV 986
Score = 39.3 bits (90), Expect = 0.022
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 4/104 (3%)
Query: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI--REDPK 1093
P ++ P F+ + + + G A L+ V G PKPK+ W N + + D K
Sbjct: 3637 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3696
Query: 1094 FLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
F+ L + + D G YTC A N+ G+ + L++
Sbjct: 3697 FVFDGDDHSLIILFTKLE--DEGEYTCMASNDYGKTICSAYLKI 3738
Score = 38.9 bits (89), Expect = 0.028
Identities = 19/61 (31%), Positives = 31/61 (50%)
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+V W ++ K+ IT GV L ++ + D GTY C+ VN+ GE + +L V
Sbjct: 25294 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353
Query: 1138 R 1138
+
Sbjct: 25354 K 25354
Score = 38.1 bits (87), Expect = 0.048
Identities = 48/197 (24%), Positives = 83/197 (42%), Gaps = 29/197 (14%)
Query: 287 LKWFKNGQEIK----PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEK----CFTE 338
+ WF++GQ I P + F + K LTI T A+ Y + + E
Sbjct: 37 VSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTAE 94
Query: 339 LFVKEP--PVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM-WMKDGVELTREDSFKARY 395
L VK P V L+ V G +V + V V+ V+ + +DG E+ F+
Sbjct: 95 LLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQ--- 151
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQV-ITNG---GQCEAELIVEEKQLEVLQDIADLTVK 451
++G + L+ ++ ED G Y V TN AEL+V+ ++ ++ K
Sbjct: 152 -ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--------EVPAK 202
Query: 452 ASEQAVFKCEVSDEKVT 468
++ V ++S+ + T
Sbjct: 203 KTKTIVSTAQISESRQT 219
Score = 37.7 bits (86), Expect = 0.063
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 14/105 (13%)
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
T+R + PP+ LP + + Y VGE + V P P V W K G ++
Sbjct: 25377 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIK 25426
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG 934
D D + SD G Y+L++ D A + K G
Sbjct: 25427 PGDNDK----KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 25467
Score = 37.4 bits (85), Expect = 0.082
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 21/97 (21%)
Query: 237 DLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQE 295
DLRG+ ++L AK G+ IK+ + + P T+ W K Q
Sbjct: 14761 DLRGIYQKLVIAKA--------------------GDNIKVEIPVLGRPKPTVTWKKGDQI 14800
Query: 296 IKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKD 332
+K + + FE IL IN+C +D Y + ++
Sbjct: 14801 LKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14837
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 22/93 (23%)
Query: 1006 VYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSA 1065
VYT + G K +AR+ TGI K F++PL D+ V G +A
Sbjct: 5248 VYTAEVEG-------KKTSARLFVTGIRLK--------------FMSPLEDQTVKEGETA 5286
Query: 1066 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITN 1098
C + H K VVW KN ++ LI++
Sbjct: 5287 TFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISS 5318
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 1/82 (1%)
Query: 252 VKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKK 310
V S KL V G ++ I P T KW +G EIK Y E
Sbjct: 11201 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11260
Query: 311 RILTINKCTLADDAAYEVAVKD 332
+LTI C D Y++ V +
Sbjct: 11261 SVLTIKNCLRRDTGEYQITVSN 11282
Score = 36.2 bits (82), Expect = 0.18
Identities = 57/267 (21%), Positives = 99/267 (37%), Gaps = 40/267 (14%)
Query: 874 WTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W + G L T+ + + + D GEY + ++ K +A +++ V+
Sbjct: 2606 WLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVKI 2663
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT 992
N+ V E VE P G I V ++++K + + + S
Sbjct: 2664 KKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEK----YAISVKGTIYSLR 2719
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
+ + + +E VY + L S + T +I+K PK +T
Sbjct: 2720 IKNCAIVDE---SVYGFRLGRLGASARLHVETVKIIKK-----------------PKDVT 2759
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
L + V S + H V W +EI+ K + + + V L ++ SP
Sbjct: 2760 ALENATVAFEVSVS-------HDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2812
Query: 1113 FDAGTYTCRAVNELGEALAECKLEVRV 1139
DAG YT V +L ECK ++ V
Sbjct: 2813 SDAGEYTA-VVGQL-----ECKAKLFV 2833
Score = 36.2 bits (82), Expect = 0.18
Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P F L + G S V G P P + W K+ + P I ++G+
Sbjct: 25485 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25543
Query: 1103 --LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+IR P D G Y A N G + L+V
Sbjct: 25544 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25580
Score = 34.7 bits (78), Expect = 0.53
Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 243 KRLKKAKVEVKKSAA--FTKKLDPAYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPS 299
K AK+ V K AA +K++P +V G+ K EI S P++ +WFK G+EI S
Sbjct: 4514 KTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFKAGREIYES 4572
Query: 300 SKYVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKEP 344
K + L I + + D Y +E C L V P
Sbjct: 4573 DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4621
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDTVFFVRQAAR 904
Q+ + G G P P+V W + G + TS V + SD + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
++SG Y L + + T+T + V + PP
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 268 VDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G ++L++ I+ P WF G +++ S + E K LTI + T+ D Y
Sbjct: 23445 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEY 23504
Query: 327 EVAVKD 332
+ +K+
Sbjct: 23505 TLELKN 23510
Score = 32.3 bits (72), Expect = 2.6
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 873 VWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
VW K G + S RVH+ + + + D+G Y ++ + + + + V+
Sbjct: 2341 VWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400
Query: 932 KAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
P +V V E GT A++E + D S
Sbjct: 2401 VITPLKDVNVIE--GTKAVLECKVSVPDVTS 2429
Score = 32.0 bits (71), Expect = 3.4
Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 268 VDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K+ + V + P T+ W K+G+E+K S + +N L + K AD Y
Sbjct: 8093 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 8152
Query: 327 EVAVKDE 333
+ ++++
Sbjct: 8153 TITLENK 8159
Score = 31.6 bits (70), Expect = 4.5
Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 6/122 (4%)
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK-----FLTPLIDRVVVAGY 1063
+N+C L ++++A I+ I E H F + F L D V
Sbjct: 2085 DNVCELVIRDVTAEDSASIMVKAINIAG-ETSSHAFLLVQAKQLITFTQELQDVVAKEKD 2143
Query: 1064 SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAV 1123
+ A P KV W K+ ME+ E K+ + + + V L+I DA Y+C V
Sbjct: 2144 TMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 1124 NE 1125
+
Sbjct: 2204 ED 2205
Score = 31.6 bits (70), Expect = 4.5
Identities = 60/257 (23%), Positives = 100/257 (38%), Gaps = 50/257 (19%)
Query: 45 PTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGAR 103
PT +F + + + G+ +V+G +P PT+KW K G+ L LG
Sbjct: 25483 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG--IPP-PTLKWEKDGQPLSLGPNI--- 25536
Query: 104 FSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPR-QDASG 162
E + + Y LHI + D GYYR+ SC ++ VE R +
Sbjct: 25537 ----EIIHEGLDYYA--LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEF 25590
Query: 163 QSLESFKRTSEKKSDTAGELDFSGLLKKREVV--EEEKKKKKKDDDDLGIPPEIWELLKG 220
+S E +R +K+ D L + +L E V + K+ ++ L P + +KG
Sbjct: 25591 KSKEEHERHVQKQIDKT--LRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKG 25648
Query: 221 ------AKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKI 274
+K E K+ Y + + R + K+ +E +I
Sbjct: 25649 EFRLEIEEKKEERKLRMPYDVPEPR----KYKQTTIE------------------EDQRI 25686
Query: 275 KLMVEISDPDLTLKWFK 291
K V +SD +KW+K
Sbjct: 25687 KQFVPMSD----MKWYK 25699
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 261 KLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCT 319
KL V G KI+L ++ P+ + W K +K + ENV KK +TI
Sbjct: 7390 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSK 7449
Query: 320 LADDAAY 326
+D Y
Sbjct: 7450 RSDTGTY 7456
Score = 30.8 bits (68), Expect = 7.7
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+FL PL D V A C + KV W K+ EI++ K+ I + V L I
Sbjct: 6070 EFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVIN 6128
Query: 1109 RPSPFDAGTYTC 1120
+ D Y+C
Sbjct: 6129 KCLLDDEAEYSC 6140
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 275 bits (704), Expect = 1e-73
Identities = 222/790 (28%), Positives = 337/790 (42%), Gaps = 43/790 (5%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
++S +KW++NG+EIK KY FE G L I C L D+ Y V+D K
Sbjct: 6473 QLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRAR 6532
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
LFV+E PV I+ P +D G V E++++ +V W+++ + + + D +++
Sbjct: 6533 LFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD----KHQMM 6588
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEA--ELIVEEKQLEVLQDIA-----DLTVK 451
+GK H L D+ D+G Y+ I + A EL K QD+ LT+
Sbjct: 6589 SEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMV 6648
Query: 452 ASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
A K E +W+K E P TI I + + D+G Y V
Sbjct: 6649 VPYDAYPKAEA-------EWFK---ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIV 6698
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
+N I V + D + + G+K+ + +
Sbjct: 6699 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKI-IGYVVERR 6757
Query: 572 PPPVATWLKGDEVFTTTEGR-TRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS 630
TW+ + + E T ++K F + + R G ++ NPV + S
Sbjct: 6758 DIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE-PVETDNPV--EARS 6814
Query: 631 IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRW---MK 687
+ DVP PP V IT V L WEPP YDGG +T Y++E + K S RW M
Sbjct: 6815 KY----DVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 6870
Query: 688 LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHL 743
+ E + T T ++EG Y RV A N IGV +PS T PF+ PI S P++L
Sbjct: 6871 VRAEDLSATV---TDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNL 6926
Query: 744 IVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPT 803
D T ++ LKW PP + G I GY++E C EG + W+ N + V + V L
Sbjct: 6927 TSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK 6986
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP 863
G + L+RV N AG S+P+ + P+T + P + L + V + ++VP
Sbjct: 6987 GNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVI-VPNPITILVP 7045
Query: 864 FQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
G PRP W G L+T RV ++T + + RSD G Y L ++ +
Sbjct: 7046 STGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7105
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I + V+ + P + ++ + + W+ P DDG S + GY V+K + W V
Sbjct: 7106 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 7165
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+ TV DL+ G EY F+V N CG + V + + P K
Sbjct: 7166 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWR 7225
Query: 1043 DFRMAPKFLT 1052
D FLT
Sbjct: 7226 DRTANSIFLT 7235
Score = 274 bits (701), Expect = 3e-73
Identities = 167/480 (34%), Positives = 243/480 (50%), Gaps = 13/480 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP+I LD + +V+ A LRL V+I G P P W K + + T R +IE
Sbjct: 18731 EPPEIELDADLR---KVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTD---RAQIEV 18784
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ VI++ R D GRY + + N G A + ++V+D P P + I V +D
Sbjct: 18785 TSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVT 18844
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L WEPP+ DGG +T Y+VE+++ + + + T+TT+ + EG Y RV A
Sbjct: 18845 LSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC-TKTTFRIENLQEGCSYYFRVLAS 18903
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G+ P+ T+P P P + + DVT T T+KW P G I GY+VE
Sbjct: 18904 NEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 18963
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
+GSE+W + V+ T+ L G +FRV VN GRS+P L PV R+I
Sbjct: 18964 TKGSEKW--STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEI 19021
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDT 895
P + LP H T+ K EQL + VPF+G+P+ V W K G L +T+RV+V +S T
Sbjct: 19022 KPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT 19078
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++A++ D G YEL V T I I V+++ GPP + + EV + + W
Sbjct: 19079 SLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 19138
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG +I Y V+K + + W V + TS + L G+EY FRV EN G S
Sbjct: 19139 PEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19198
Score = 265 bits (678), Expect = 1e-70
Identities = 169/568 (29%), Positives = 272/568 (47%), Gaps = 23/568 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P++ LD + IVV AG R+ + G P P TW + + FT + +I
Sbjct: 17646 KLEAPELDLDSELR---KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD---KVQI 17699
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
EK V+ + I++ R D G+Y +K+ N G A + ++V+D P PP+ + + V +D
Sbjct: 17700 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDS 17759
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A LVWEPP+ DGG V Y++++++ + + ++ + ++T+++ + EG +Y RV
Sbjct: 17760 AFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKC-SKTSFKVENLTEGAIYYFRVM 17818
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N GV P P S P + + DV+ T+ +L W P G + GY+VE
Sbjct: 17819 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17878
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G+E+W V C V L +G FRV N G+S+P L PV +++
Sbjct: 17879 MQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 17936
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDF 893
P ++LP + TY + GE L + +P G+PRP + W K G PL T+RV+V +
Sbjct: 17937 TIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETAT 17993
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
TV +++ + D G+Y ++ T + + V+EK GPP+ V EV ++
Sbjct: 17994 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 18053
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ P G +I Y V+K D T W V T+ ++ L G EY FR++ EN
Sbjct: 18054 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRY 18113
Query: 1013 GLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC 1069
G S DS V + G PF +M ++ P+ D G + +
Sbjct: 18114 GKSAPLDSKAVIVQYP-FKEPGPPGTPFVTSISKDQMLVQWHEPVND-----GGTKIIGY 18167
Query: 1070 AVRGHPKPKVVWMKNKMEIREDPKFLIT 1097
+ K ++W+K +D KF T
Sbjct: 18168 HLEQKEKNSILWVKLNKTPIQDTKFKTT 18195
Score = 261 bits (668), Expect = 2e-69
Identities = 175/561 (31%), Positives = 269/561 (47%), Gaps = 37/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+ G ++R S+R+T+ + KL I + D G+YT + S IKV
Sbjct: 23400 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 23454
Query: 531 EYVPKQEPPK--IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKG---DE 583
+ K PP I +D TS ++I+ EPP + L G ++
Sbjct: 23455 IILDKPGPPTGPIKIDEIDATS---------------ITISWEPPELDGGAPLSGYVVEQ 23499
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--VGEDVASIFLQV---VDV 638
G + + V S+F +E + + TN +G + S ++ + +
Sbjct: 23500 RDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRI 23559
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PPE ++I V D L W PP DGG VTGY+VERK+ + RW+++N T T Y
Sbjct: 23560 PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRY 23619
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
ST + EG+ YE RV A+NA G +PS +KP + PIAP +P + V D T T+ +L
Sbjct: 23620 RSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 23679
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
W P G + GYL+E EW NT P + +T+ +LP GA FRV+ N
Sbjct: 23680 AWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACN 23739
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
G EPA + V + E+ E P L ++ + G + L +P +GKP P WT
Sbjct: 23740 AGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWT 23799
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K G + + R + TS+ T +++A R DSG Y+L ++ + K I++RV+
Sbjct: 23800 KEGQDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNS 23858
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + V W+ P DDG ++I+GY +++ + W+ + R R TS V
Sbjct: 23859 PEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVK 23918
Query: 995 DLIVGNEYYFRVYTENICGLS 1015
L EY+FRV EN G+S
Sbjct: 23919 GLKENVEYHFRVSAENQFGIS 23939
Score = 252 bits (644), Expect = 1e-66
Identities = 177/599 (29%), Positives = 286/599 (47%), Gaps = 32/599 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ VKA E +++ + W K+G+E+ R I L + D D G
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTG 19486
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A + S +N + + K PP L+ +G T+E + + + + D
Sbjct: 19487 QYVLTLKNVAGTRSVAVN-----CKVLDKPGPPAGPLEINGLTAEKCSL--SWGRPQEDG 19539
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--V 624
+ V +T EG ++ +S + + +E + + N V
Sbjct: 19540 GADIDYYIVEKRETSHLAWTICEGELQM------TSCKVTKLLKGNEYIFRVTGVNKYGV 19593
Query: 625 GEDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKG 681
GE + S+ ++ +D VP PP ++ ITSV ++ L W P DGG ++GY++ER++K
Sbjct: 19594 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19653
Query: 682 SQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPT 737
S RW+++N + + +ST + EG YE RV+A NA G+S PS T P + P+
Sbjct: 19654 SLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPS-ETSPLIRAEDPVFLP 19712
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
S P + D TT T+ W P G I GY VEY +W + + + +T
Sbjct: 19713 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYT 19771
Query: 798 VKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQ 857
+ L TGA +FRV VN G S+P+ + P +E E P + +R+T I K G
Sbjct: 19772 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19831
Query: 858 LNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ VPF+G+P P V+W+K L T R +V T+D T + A R+DSG+Y L++Q
Sbjct: 19832 FTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNV 19890
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ T+ ++V++ GPP N+ V++V +A++ W P++DG + + Y ++K +
Sbjct: 19891 LSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKK 19950
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
W +V S V++L G YYFRV EN G+ G+ T +K IT KP
Sbjct: 19951 AWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV----GIPAETKEGVK--ITEKP 20003
Score = 249 bits (637), Expect = 8e-66
Identities = 181/600 (30%), Positives = 287/600 (47%), Gaps = 38/600 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
LTVKA V + + T W K+G ++P++ I ++ L + V +D G
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12992
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
DYT + + S SA IK++ + K PP V NK+ D
Sbjct: 12993 DYTITAENSSGSKSAT-----IKLKVLDKPGPP---------------ASVKINKMYSDR 13032
Query: 567 SITGEPPPVA------TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
++ PP+ T D+ T+ ++ V +S +E E ++ I
Sbjct: 13033 AMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICA 13092
Query: 621 TNP--VGEDVASIFLQVVDVPDPP---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N VG+ V + + DPP + I+++ +D + W+PP DGG P+TGYL+
Sbjct: 13093 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLL 13152
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
E+++ + W K+N + E T ++T + EG YE RV A+N G +PS +K
Sbjct: 13153 EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARD 13212
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT-EPV 791
P P P V D T ++ +L W P G I GYLVE S+ WV N + +
Sbjct: 13213 PQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13272
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
++ F V L + FRV VN G S+P+ + ++I PP+ L LR+T I
Sbjct: 13273 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 13332
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEY 910
+ G + L VP +G+P P++ W+K L D + ++++DFDT + D+G+Y
Sbjct: 13333 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13392
Query: 911 ELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ 970
L+++ K TI ++V++ GPP+NV VKE+ +A V W+ P DG S I+ Y VQ
Sbjct: 13393 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 13452
Query: 971 KADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKT 1030
K D + W V TS V++L G Y+FRV+ EN G+ D PG +++ + +T
Sbjct: 13453 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD-PGETRDAVKASQT 13511
Score = 246 bits (628), Expect = 9e-65
Identities = 155/494 (31%), Positives = 245/494 (49%), Gaps = 17/494 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
+E + P + LD S + + IVV AG +R+ ++G+PPP TW + T
Sbjct: 10141 IEMKDRLVSPDLQLDASVR---DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER---TLP 10194
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT- 648
IE SS VI++ QR +G Y++ N GE +I + V+DVP P +
Sbjct: 10195 QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAH 10254
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
++ + L W P DGG P+T Y++E+++ + W + + V T +I+G
Sbjct: 10255 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV-TRQNATVQGLIQGKA 10313
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y R+ A N+IG+ P + T + PI P L V++VT T TL W PP G
Sbjct: 10314 YFFRIAAENSIGMG-PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDG 10372
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I Y++E L G+E++ + + +TVK L G +RV VNI G+ +P+
Sbjct: 10373 GSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF 10432
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAP-LDT 883
+P+T ++ PP + L R +VGE L + GKP+P+V W K A L+
Sbjct: 10433 CTKPITCKDELAPPTLHL--DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLED 10490
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVK 942
R H++T+ +A RSDSG+Y + V+ ++ VV++ GPP+ V
Sbjct: 10491 DRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFD 10550
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
EV ++ W+ P DDG S+I Y ++K + W V + T+C VS L+ G +Y
Sbjct: 10551 EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 10610
Query: 1003 YFRVYTENICGLSD 1016
FR++ EN+ G+SD
Sbjct: 10611 IFRIHAENLYGISD 10624
Score = 246 bits (627), Expect = 1e-64
Identities = 150/488 (30%), Positives = 235/488 (48%), Gaps = 9/488 (1%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
++E V + E P + L + + + AG LRL VS++G PPPV TW K
Sbjct: 23062 EIEPVERIEIPDLEL---ADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQG---IDL 23115
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
R I+ S +++ R D G+YTI+ N G+ A++ ++V D P P +V++
Sbjct: 23116 ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVK 23175
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V D + WE P DGG PV Y+VE K++ + R K ++T Y + ++EG +
Sbjct: 23176 EVSRDSVTITWEIPTIDGGAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTM 23234
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y RV N G+ +P + + P L V DVT +T TL W P G +
Sbjct: 23235 YYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRL 23294
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
GY++E C G+E W+ T TV +L G + LFR+ N G SEP
Sbjct: 23295 TGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 23354
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVH 887
VT++++ P I L ++T G + LV+P G+P P W G+ L ++ RV
Sbjct: 23355 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 23414
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWG 946
V T +R+ D+GEY L ++ + TI++ +++K GPP + + E+
Sbjct: 23415 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 23474
Query: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRV 1006
T+ + W+ P+ DG + + GY V++ D W V E ++ + L GNEY FRV
Sbjct: 23475 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 23534
Query: 1007 YTENICGL 1014
N G+
Sbjct: 23535 AATNRFGI 23542
Score = 243 bits (620), Expect = 8e-64
Identities = 162/502 (32%), Positives = 240/502 (47%), Gaps = 27/502 (5%)
Query: 527 EIKVEYVPKQ--EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEV 584
E+K PK+ EPP+I LD S + ++V AG +RL + G P P TW K
Sbjct: 12218 ELKEAIKPKEILEPPEIDLDASMR---KLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID 12274
Query: 585 FTTTEGRTRIEKRVDCSSF-VIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
+G+ + VD +F VI ++ R+D G+Y++ + NP GE + ++V+D P P
Sbjct: 12275 NVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVS 12331
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++++ V + + W PP DGG VT Y+VE+++ + W + EV +T++ T +
Sbjct: 12332 DLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNL 12390
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSE---PLHLIVEDVTDTTTTLKWRPP 760
+ G Y RV AVN G P+ KP + P SE P L V ++T + TL W PP
Sbjct: 12391 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 12450
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANT----EPVERCGFTVKNLPTGARILFRVVGVNI 816
R G IDGY+ Y EE PA+ V+ V L G + FRV N
Sbjct: 12451 LRDGGAKIDGYITSY----REEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNA 12506
Query: 817 AGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P +E PPKI +P + K G++L + GKP P W K
Sbjct: 12507 VGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKK 12562
Query: 877 GGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G + T S + V +D ++ ++ R DSG Y L+ + + DT I++ V++ GP
Sbjct: 12563 GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGP 12622
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + W P +DG S I Y V+K D +W TSC V
Sbjct: 12623 PQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVG 12682
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
LI G EY FRV EN G+S+
Sbjct: 12683 KLIPGQEYIFRVRAENRFGISE 12704
Score = 239 bits (610), Expect = 1e-62
Identities = 152/487 (31%), Positives = 236/487 (48%), Gaps = 22/487 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P I LD + N + AG LRL V I G P P W K D G R
Sbjct: 16564 KLEAPDIDLDLELRKIIN---IRAGGSLRLFVPIKGRPTPEVKWGKVD-------GEIRD 16613
Query: 595 EKRVDCSS----FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSV 650
+D +S V+++ R D G+YT+ + N G A + ++V+D P PP +++T +
Sbjct: 16614 AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEI 16673
Query: 651 GEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYE 710
+D + WEPP+ DGG + Y+VE+++ + + + + +++ ++ EG Y
Sbjct: 16674 TKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCH-KNSWKIDQLQEGCSYY 16732
Query: 711 MRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDG 770
RV A N G+ P+ P P + V+DVT + +L W P G I
Sbjct: 16733 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 16792
Query: 771 YLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
Y+VE + SE+W + V+ + NL G LFRVV VN GRS+P +LA P+
Sbjct: 16793 YIVEMQAKHSEKW--SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIV 16850
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVR 889
+++ P + + +Y +VG+ L + VP G+P+P + WTK G PL T+R++V
Sbjct: 16851 AKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 16907
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTN 948
S T +++ + D G+Y ++V + TA+I I ++K PP V +V +
Sbjct: 16908 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES 16967
Query: 949 ALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYT 1008
+ W P G +I Y VQK D T W V T+ V+ L G EY FR++
Sbjct: 16968 ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFA 17027
Query: 1009 ENICGLS 1015
EN G S
Sbjct: 17028 ENRYGQS 17034
Score = 238 bits (607), Expect = 2e-62
Identities = 178/616 (28%), Positives = 277/616 (44%), Gaps = 39/616 (6%)
Query: 429 EAELIVEEKQLEVLQDIA---DLTVKASEQAVFKCEVSDEK-VTGKWYKNGVEVRPSKRI 484
EAE + E K+ + I +T+KA ++ + V + T KW K EV S +
Sbjct: 12514 EAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL 12573
Query: 485 TISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLD 544
+ L+I DV +D G Y+ + S+ + +IKV + PP+ D
Sbjct: 12574 AVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKVVVMDAPGPPQPPFD 12628
Query: 545 CSGKTSENA-----IVVVAGNKLRLDVSITGEPPPVATWLKGDEVF---TTTEGRTRIEK 596
S ++ I + G +IT +GD V + T+ R+ K
Sbjct: 12629 ISDIDADACSLSWHIPLEDGGS-----NITNYIVEKCDVSRGDWVTALASVTKTSCRVGK 12683
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ E R+ I + VA VP P+ R+T V +D
Sbjct: 12684 LIPGQEYIFRVRA---ENRFGISEPLTSPKMVAQF---PFGVPSEPKNARVTKVNKDCIF 12737
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
+ W+ P DGG P+ GYL+ERK++ S W+K N + T Y ++EG+ Y R++A+
Sbjct: 12738 VAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 12797
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G S PS T+ P P V DVT +T +L W P G I GY VE C
Sbjct: 12798 NKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC 12857
Query: 777 LEGSEEWVPANTEP--VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
++WV NT P + + +T L A+ FR + S P+ + PVTI
Sbjct: 12858 KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE 12917
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA---PLDTSRVHVRTS 891
PP+I L ++ K G + L GKP P V W K G P + ++ ++ +
Sbjct: 12918 NVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN 12977
Query: 892 DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALV 951
F R DSG+Y ++ + + +ATI+++V++K GPP +V + +++ A++
Sbjct: 12978 LCTLELF--SVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAML 13035
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P +DG SEI Y V K + W V TSC+V LI G+EY FR+ EN
Sbjct: 13036 SWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENK 13095
Query: 1012 CGLSD----SPGVSKN 1023
G+ D P ++KN
Sbjct: 13096 YGVGDPVFTEPAIAKN 13111
Score = 238 bits (606), Expect = 3e-62
Identities = 157/496 (31%), Positives = 232/496 (46%), Gaps = 19/496 (3%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP++ LD + ++ + G+ LRL I G P P TW K D T + RI+
Sbjct: 10842 EPPELILDANMAREQH---IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT---KARIDV 10895
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
S I +A ED G Y++ V NP G S+ + V+D P PP + ++ + +D
Sbjct: 10896 TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10955
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W+ P+ DGG +T Y+VER+ S +W L+ + ++ + + EG Y RV A
Sbjct: 10956 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAE 11014
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G KP P+ P P L DV T +L W P+R G I GYLV
Sbjct: 11015 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11074
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
EY EG+++W+ T C V L G FRV NI G P T P+ +E
Sbjct: 11075 EYQEEGTQDWIKFKTVTNLEC--VVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 11131
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH-VRTSD 892
PP + L L + + K G + +G P P WT G+ + T + V T +
Sbjct: 11132 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11191
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALV 951
F +V ++ R D+GEY+++V T + + V++ GPP + + +V + +
Sbjct: 11192 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11251
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
WQ PKDDG S ++ Y V+K D + W V + T + L G EY FRV EN
Sbjct: 11252 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 11311
Query: 1012 CG----LSDSPGVSKN 1023
G L +P V+K+
Sbjct: 11312 IGVGPPLDSTPTVAKH 11327
Score = 234 bits (598), Expect = 3e-61
Identities = 149/496 (30%), Positives = 239/496 (48%), Gaps = 18/496 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
VE V ++ P LD + + +VV AG +R+ V I G P P TW K + +
Sbjct: 14393 VEIVEREMAPDFELDAELRRT---LVVRAGLSIRIFVPIKGRPAPEVTWTKDN---INLK 14446
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
R IE + +I R D G++ + + NP G+ + ++V+D P P +R T
Sbjct: 14447 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTD 14506
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ +D L W+ P+ DGG +T Y+VE+++ + + + + TY+ T + EG Y
Sbjct: 14507 ITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH-KCTYKVTGLSEGCEY 14565
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
RV A N G+ +P+ T+P S P L + D+T +T +L W P G I
Sbjct: 14566 FFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKIT 14625
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
GY++E +GS++W T C V+NL G F+V+ VN AGRS P ++PV
Sbjct: 14626 GYVIEAQRKGSDQWTHITTVKGLEC--VVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPV 14682
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHV 888
++E P++ L ++ I K G+ + + +P G+P+P V W KG L T RV+
Sbjct: 14683 IVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNF 14742
Query: 889 RTSDFDTVFFVRQAARSDSGEYELSVQ--IENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
T+ T+ + + RSDSG Y L+ + + + D TI++ + GPP + EV
Sbjct: 14743 ETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI--PGPPTGPIKFDEVS 14800
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
W P++DG I Y V+ + W + T+ + L G EY FR
Sbjct: 14801 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 14860
Query: 1006 VYTENICGLSDSPGVS 1021
V +N G+ PG++
Sbjct: 14861 VKAQNRYGV--GPGIT 14874
Score = 232 bits (592), Expect = 1e-60
Identities = 161/551 (29%), Positives = 248/551 (45%), Gaps = 28/551 (5%)
Query: 469 GKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
G W+K E R T++ + G +K + + +GD V
Sbjct: 21926 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG------------- 21972
Query: 527 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 586
++ V + P++ +D + K + VV AG +RL ++ G P P A W K D +
Sbjct: 21973 --TIKAVDRLTAPELDIDANFKQTH---VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 22027
Query: 587 TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVR 646
R I S+ +E+ R D G+YT+ V N G + ++V+D P PP +
Sbjct: 22028 L---RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPIT 22084
Query: 647 ITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEG 706
V A L+W+ P+ DGG + Y+VE+++ + W ++ E T ++ + EG
Sbjct: 22085 FKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDLAEG 22143
Query: 707 ILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAG 766
+ Y RV AVN GV +P +P + + P L V D + ++ L W P+ G
Sbjct: 22144 VPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGS 22203
Query: 767 GIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA 826
I GYL+E +GS+ WV A ++ FTV+ L FRV N AG SEP
Sbjct: 22204 RITGYLLEMRQKGSDFWVEAG--HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 22261
Query: 827 QPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSR 885
V I+E P L Q K G + VP G+P P+V W L +T R
Sbjct: 22262 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDR 22321
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
V + T+ T V+ + R DSG Y L+++ T ++ + V+ + GP + V V
Sbjct: 22322 VSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV 22381
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
+ ++ W PKD G +EI Y V+K + T W V + T V+ L EY F
Sbjct: 22382 SAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSF 22441
Query: 1005 RVYTENICGLS 1015
RV +EN G+S
Sbjct: 22442 RVSSENRFGVS 22452
Score = 231 bits (588), Expect = 4e-60
Identities = 141/480 (29%), Positives = 230/480 (47%), Gaps = 7/480 (1%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ + V+ N + + V TG P P ATW GD+V T + R +++ + VI ++R
Sbjct: 7029 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD-RVKMKTLSAYAELVISPSER 7087
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
D+G YT+K+ N V I + V+ P P+ ++ + +D L WEPP DGG P+
Sbjct: 7088 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7147
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
TGY+VE+++ + W K+ + T+ + +++G Y +V A N G +P+ +P
Sbjct: 7148 TGYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEP 7206
Query: 731 FMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPAN 787
P + P ++ D T + L W PP G I GY+VE C GS++WV
Sbjct: 7207 VNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 7266
Query: 788 TEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
EPV V L G +RV +N G S+P+ + + + E P+I L L
Sbjct: 7267 -EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL 7325
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSD 906
K G ++ L GKP P++ WTK L R+ + + + + RSD
Sbjct: 7326 AGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSD 7385
Query: 907 SGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966
+G Y + + TA + + V++K GPP + +V + L+ W P+DDG S+I
Sbjct: 7386 TGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7445
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y V++ + W + + T+ + LI EY FRV EN+ G+ + S TA+
Sbjct: 7446 YVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAK 7505
Score = 228 bits (581), Expect = 3e-59
Identities = 138/484 (28%), Positives = 226/484 (46%), Gaps = 11/484 (2%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
++E P +D + + ++V AG + V G P P W K D T R +
Sbjct: 19808 REEEPLFDIDSEMRKT---LIVKAGASFTMTVPFRGRPVPNVLWSKPD---TDLRTRAYV 19861
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ +S IE+A R D G+YT+ + N + ++ ++V+D P PP + + V ++
Sbjct: 19862 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKES 19921
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A+L W+ P DGG PV Y +E+++ + W+ + +Y+ T + EG +Y RV
Sbjct: 19922 AVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKVTNLQEGAIYYFRVS 19980
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N GV P+ + S P L V ++ + +L W P G I Y+VE
Sbjct: 19981 GENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVE 20040
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G + WV + V L + FRV N AG S+P L PV I+E
Sbjct: 20041 ALEKGQKNWVKCAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQ 20098
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDF 893
EPP+I + T + G L + +P GKP P+V ++ G PL T R + +
Sbjct: 20099 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20158
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+ ++++ +D+G YE++ + A I I V+++ GPP V++ ++ + ++
Sbjct: 20159 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLK 20218
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ PK DG S++ Y + K + T W V T V L G EY FR+ EN
Sbjct: 20219 WEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRF 20278
Query: 1013 GLSD 1016
G+SD
Sbjct: 20279 GISD 20282
Score = 226 bits (577), Expect = 7e-59
Identities = 133/383 (34%), Positives = 202/383 (52%), Gaps = 10/383 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE-VFTET 696
VPD P+ +T V +D A++ W P +DGGKP+T Y++E+++ S+RW ++ + + T
Sbjct: 10639 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 10697
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTT 753
+ ++EG YE RV A N IG+ PS +KP PIA S P++ D T +
Sbjct: 10698 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10757
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT---VKNLPTGARILFR 810
L W+PP G I GY+VEY G EEW AN P E C T V L G FR
Sbjct: 10758 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTP-ESCPETKYKVTGLRDGQTYKFR 10816
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V+ VN AG S+PA + +PV +++ EPP++ L ++ + KVG+ L L +G P P
Sbjct: 10817 VLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP 10876
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
+V W K T + + + + +R AA D G Y L+V+ T ++++ V+
Sbjct: 10877 KVTWKKEDRDAPT-KARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVL 10935
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTS 990
+K GPP ++ V E+ + + W+ P DDG S I Y V++ D + +W + ++ S
Sbjct: 10936 DKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKS 10995
Query: 991 CTVSDLIVGNEYYFRVYTENICG 1013
L GN+Y FRV EN G
Sbjct: 10996 HFAKHLNEGNQYLFRVAAENQYG 11018
Score = 225 bits (574), Expect = 2e-58
Identities = 147/490 (30%), Positives = 230/490 (46%), Gaps = 22/490 (4%)
Query: 534 PKQE----PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK--GDEVFTT 587
PK E PP+I LD + + + A LRL V I G P P W + G+ +
Sbjct: 15477 PKAEDRMLPPEIELDADLR---KVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--- 15530
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ IE + ++ + R D G+Y + V N G A + ++V+D P PP+ +++
Sbjct: 15531 --DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKV 15588
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
V + L W+PP+ DGG + Y+VE+++ + + + +T+++ ++ EG
Sbjct: 15589 KEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCH-KTSWKVDQLQEGC 15647
Query: 708 LYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
Y RV A N G+ P+ + P + + DVT + +L W P G
Sbjct: 15648 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSR 15707
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
I GY+VE +GS++W T V T+ L G FRV N G S+P L+
Sbjct: 15708 ILGYIVEMQTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSV 15765
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRV 886
PV +++ PP +L L T+ GE L + VPF G+P P V W K PL T+RV
Sbjct: 15766 PVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRV 15822
Query: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
+ +++ +++ ++ A R D G Y + + + T+ + V++K GPP V + EV
Sbjct: 15823 NAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT 15882
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
+ + W PK DG S I Y V+K D T W V T+ L G EY FR
Sbjct: 15883 ADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15942
Query: 1006 VYTENICGLS 1015
+ EN G S
Sbjct: 15943 IAAENRYGKS 15952
Score = 219 bits (557), Expect = 2e-56
Identities = 145/484 (29%), Positives = 237/484 (48%), Gaps = 18/484 (3%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE-K 596
PP+ LD + + +++ AG +RL V + G PPP TW K + R ++ K
Sbjct: 13318 PPEGELDADLRKT---LILRAGVTMRLYVPVKGRPPPKITWSKPN---VNLRDRIGLDIK 13371
Query: 597 RVDCSSFV-IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
D +F+ E+ + D G+Y + + N G+ +I ++V+D P PP V + + +D A
Sbjct: 13372 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13431
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WEPP+ DGG P+ Y+V+++ + W + E ++T++ + EG Y RVFA
Sbjct: 13432 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFA 13490
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPL-HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N G+ P T+ + + T P+ L V V+ ++ ++ W+ P+ G I GY+V+
Sbjct: 13491 ENEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 13549
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+ E ++ + ++ ++ K+L G FRV N G P+ + V R+
Sbjct: 13550 FLTEENKWQRVMKSLSLQ---YSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDD 13604
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDT-SRVHVRTSDF 893
P + L Y+ K L +P +GKP P V W KG PL T +RV V +S
Sbjct: 13605 VVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAV 13664
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+T V +SD+G+Y ++++ TI I+VV K G P + EV ++
Sbjct: 13665 NTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLK 13724
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W PKDDG SEI Y ++K D +W + T+ V+ L G EY FRV EN
Sbjct: 13725 WAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKY 13784
Query: 1013 GLSD 1016
G+ +
Sbjct: 13785 GVGE 13788
Score = 218 bits (556), Expect = 2e-56
Identities = 158/516 (30%), Positives = 233/516 (45%), Gaps = 54/516 (10%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+++ V QE P+I LD + V AG K+ L ++TG+P P TW K D +
Sbjct: 7306 EIQAVDTQEAPEIFLDVKLLAG---LTVKAGTKIELPATVTGKPEPKITWTKADMILKQD 7362
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
+ R IE S+ I ++R D G Y I+ N G A + + V+D P PP A IT
Sbjct: 7363 K-RITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDIT 7421
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V + +L W PP DGG +T Y+VER+ S+ W KL+ V +T +++TK+I
Sbjct: 7422 DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKLIPNKE 7480
Query: 709 YEMRVFAVNAIGVSQPSMNTKPF---MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGA 765
Y RV A N GV +P + P P P L D+T TL W P+ G
Sbjct: 7481 YIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7539
Query: 766 GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATL 825
I GY VE +++WV N PV+ + VK L + FRV+ N+AG +P+
Sbjct: 7540 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7599
Query: 826 AQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPL 881
+P+ I++ +PP V GK ++ WTK GGA +
Sbjct: 7600 TEPILIKDPIDPP----------------WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKI 7643
Query: 882 DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG------- 934
++ + + + D +VR A + ++ L +E + + R+R V KAG
Sbjct: 7644 ESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQE--YSFRVRAVNKAGESEPSEP 7699
Query: 935 --------------PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF 980
PP + V + A ++W P+ DG S I Y V+K D + W
Sbjct: 7700 SDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQ 7759
Query: 981 NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T CTV+ L G+ Y FRV EN G SD
Sbjct: 7760 TVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7795
Score = 218 bits (556), Expect = 2e-56
Identities = 180/670 (26%), Positives = 295/670 (44%), Gaps = 50/670 (7%)
Query: 364 EMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVIT 423
E VE +G Q W G+ T E + ++ +L F + ++G +T
Sbjct: 21124 EYVVERKGKGEQT-WSHAGISKTCE------IEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21176
Query: 424 NGGQCEAELIVEEKQLEVLQDI--ADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRP 480
G ELI+ + L DI A +TV+ + + K + W K+G+ ++
Sbjct: 21177 IGPITVKELIITPEV--DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21234
Query: 481 SKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPK 540
S+ + S L I + + E G YT + D ++ + + + PK
Sbjct: 21235 SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP--- 21291
Query: 541 IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGR--TRIEKRV 598
+ ++++ D I P G+ + E R ++ ++
Sbjct: 21292 ----------------IRFDEIKADSVILSWDVPEDNG-GGEITCYSIEKRETSQTNWKM 21334
Query: 599 DCSS-----FVIESAQREDEGRYTIKVTNPVGED---VASIFL--QVVDVPDPPEAVRIT 648
CSS F + + ++ E ++ ++ N G V+SI + +P PP I
Sbjct: 21335 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY 21394
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
+V D L W+ P+YDGG VTG+ VE+K++ S W K+N + Y +T ++EG+
Sbjct: 21395 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 21454
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y+ RV+A N+ G+S PS +K + ++P P DVT T TLKW PP R G I
Sbjct: 21455 YQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKI 21514
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQ 827
GY +E +G+E WV N V C +TV L G R FR++ N G S P+ +
Sbjct: 21515 VGYSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSG 21573
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH 887
+ R+ PP + I K GE L + QG+P P+V W K G ++ R++
Sbjct: 21574 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMN 21632
Query: 888 VRTSDF--DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
+ +D T FVR A R G Y + + + A I+++V + G + + +
Sbjct: 21633 MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNI 21692
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
G + W AP +DG + I Y ++K + + W + ++ S T LI GNEY F
Sbjct: 21693 TGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQF 21752
Query: 1005 RVYTENICGL 1014
RV N G+
Sbjct: 21753 RVSAVNKFGV 21762
Score = 218 bits (555), Expect = 3e-56
Identities = 160/568 (28%), Positives = 254/568 (44%), Gaps = 31/568 (5%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+K+ V ++ + R+ L I D ED G Y L+ SA + V
Sbjct: 15809 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVV-----KLTNSAGEAIETLNV 15863
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITG-----EPPPVATWLKGDEVF 585
+ K PP + T+++ + K SI TW ++
Sbjct: 15864 IVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW----QIV 15919
Query: 586 TTTEGRTRIEK---RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+ T RT I+ + C + A G+ T + P ++ VP PP
Sbjct: 15920 SATVARTTIKACRLKTGCE-YQFRIAAENRYGKSTYLNSEP------TVAQYPFKVPGPP 15972
Query: 643 EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTK 702
+T D + W P+ DGG V GY +ERK++ S W+KLN +T +++T
Sbjct: 15973 GTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTG 16032
Query: 703 MIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNR 762
+ EG+ YE RV A N +G+ +PS ++ ++ P P VT + TL+W+ P
Sbjct: 16033 LEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTY 16092
Query: 763 IGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSE 821
G I GY+VE W+ A+ + F V L R FRV+ N AG SE
Sbjct: 16093 DGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 16152
Query: 822 PATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL 881
P+ +T R+ +PP+I + + T + GE + GKP P + W KG L
Sbjct: 16153 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16212
Query: 882 -DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-V 939
+T+R+ ++++DF T V+ A R DSG Y L + + + T+ ++V+++ GPP V
Sbjct: 16213 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPV 16272
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVG 999
++ V + W+ P DG S+I+ Y V++ + + W V + SC V+ L+ G
Sbjct: 16273 VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG 16332
Query: 1000 NEYYFRVYTENICG----LSDSPGVSKN 1023
NEY FR+ N G L P V+KN
Sbjct: 16333 NEYTFRIMAVNKYGVGEPLESEPVVAKN 16360
Score = 218 bits (554), Expect = 3e-56
Identities = 167/650 (25%), Positives = 284/650 (43%), Gaps = 55/650 (8%)
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRIT 485
+C+ +L+ +L+V + I L VKA F + V T KW +G E++ + T
Sbjct: 11128 ECQEKLVPPSVELDV-KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11186
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDC 545
+ L I + D G+Y A S + ++ + V PP ++
Sbjct: 11187 VETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP-----GPPTGPINI 11241
Query: 546 SGKTSENAIVVVAGNKLRLDVSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVD 599
T E+ ++I+ +PP PV ++ ++ T + +
Sbjct: 11242 LDVTPEH-------------MTISWQPPKDDGGSPVINYIV-EKQDTRKDTWGVVSSGSS 11287
Query: 600 CSSFVIESAQREDEGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ I Q+ E + ++ N +G + ++ P PP +T + E+
Sbjct: 11288 KTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENA 11347
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A + W P DGG P+TGY +ER++ + +W+++N + + T + EG YE RVF
Sbjct: 11348 ATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVF 11406
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G+S+PS ++ P PI P P++ ++D + T L W P G I GY
Sbjct: 11407 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 11466
Query: 772 LVEYCLEGSEEWVPANT-EPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
+VE G+ +W N E + +C F V L G FR+ NI G EP LA+ V
Sbjct: 11467 VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVI 11526
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRT 890
++I PP++ L R +VG+ + ++ +G+P P + WTK G L +
Sbjct: 11527 AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI 11586
Query: 891 SDFDTV-FFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
D V +++A R+D G+Y +S + + + + V+++ GP N+ V V N
Sbjct: 11587 QDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENC 11646
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W+ P D+G SEI + V+ W ++ + ++L+ NEYYFRV E
Sbjct: 11647 TISWENPLDNGGSEITNFIVEYRKPNQKGW-SIVASDVTKRLIKANLLANNEYYFRVCAE 11705
Query: 1010 NICGLS---------------DSPGVSKNTARILKTGITFKPFEYKEHDF 1044
N G+ D PG +N I G TF +++ D+
Sbjct: 11706 NKVGVGPTIETKTPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDY 11754
Score = 217 bits (553), Expect = 4e-56
Identities = 125/382 (32%), Positives = 192/382 (50%), Gaps = 3/382 (0%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP PP ++T+V +D + W P+ DGG P+ GY VERK++ W ++ +
Sbjct: 14886 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 14945
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKW 757
++S+ + +GI YE RV A N G S+PS ++P + + P P + ++T T TLKW
Sbjct: 14946 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKW 15005
Query: 758 RPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIA 817
P G I Y+VE + W+ AN + FTV L A FRV+ N A
Sbjct: 15006 AKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAA 15065
Query: 818 GR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P+ + +T R+ E PKI++ + T I K GE L G+P P + W+K
Sbjct: 15066 GAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSK 15125
Query: 877 GGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G L+ T+++ ++ +DF T + + R DSG Y L+ ++V+++ GP
Sbjct: 15126 DGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP 15185
Query: 936 PIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + V EV ++ W P DDG ++I Y VQK + + W NV + T V+
Sbjct: 15186 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVT 15245
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 15246 KLLKGNEYIFRVMAVNKYGVGE 15267
Score = 217 bits (552), Expect = 6e-56
Identities = 155/560 (27%), Positives = 257/560 (45%), Gaps = 34/560 (6%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
E P+I LD + +TS ++ AG +++ + G PPP TW K DE ++ R IE
Sbjct: 20895 EAPEIDLDVALRTS---VIAKAGEDVQVLIPFKGRPPPTVTWRK-DEKNLGSDARYSIEN 20950
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS-IFLQVVDVPDPPEAVRITSVGEDWA 655
S I R D G+Y + + N VGE +S + ++V+D P + +++ V
Sbjct: 20951 TDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV 21010
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L+W+PP+ DGG P+ Y++E++ + W ++ + + T+++ + E + RV A
Sbjct: 21011 TLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLA 21069
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY 775
N IG+ +P T+P + L ++D T T+ L W P+ G I Y+VE
Sbjct: 21070 ENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 21129
Query: 776 CLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIA 835
+G + W A + C V L + + FRV N G S+P T+ P+T++E+
Sbjct: 21130 KGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELI 21186
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFD 894
P++ L ++G ++L +P++GKP+P + W K G PL S V ++
Sbjct: 21187 ITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK 21246
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV---VEKAGPPIN----VMVKEVWGT 947
++ A + G+Y + + D A RI V V GPP + E+
Sbjct: 21247 ITLSIKNAKKEHGGKYTV------ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKAD 21300
Query: 948 NALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVY 1007
+ ++ W P+D+G EI Y ++K + W V T+ V +L+ EY FRV
Sbjct: 21301 SVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVR 21360
Query: 1008 TENICGLS----DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGY 1063
EN G+S S V+K+ RI G KP Y M+ + P+ D G
Sbjct: 21361 AENRYGVSQPLVSSIIVAKHQFRI--PGPPGKPVIYNVTSDGMSLTWDAPVYD-----GG 21413
Query: 1064 SAALNCAVRGHPKPKVVWMK 1083
S V + ++W K
Sbjct: 21414 SEVTGFHVEKKERNSILWQK 21433
Score = 216 bits (551), Expect = 8e-56
Identities = 174/617 (28%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 434 VEEKQLEVLQDIADLTV-KASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR 491
VE +++V D + KA E + +VS T +W K+G E+ + ++ I
Sbjct: 15084 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15143
Query: 492 FHKLVIDDVRPEDEGDYTFV---PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
LV D D G YT P G+A + V+ + + PP+ L +
Sbjct: 15144 STNLVNKDSTRRDSGAYTLTATNPGGFAKHI--------FNVKVLDRPGPPEGPLAVTEV 15195
Query: 549 TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF-----TTTEGRTRIEKRVDCSSF 603
TSE + ++ PP K D T+ T + V +
Sbjct: 15196 TSEKCV-------------LSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 15242
Query: 604 VIESAQREDEGRYTIKVTNP--VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILV 658
+ + +E + + N VGE + S + V+ PDPP+ +T++ +D ++
Sbjct: 15243 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVC 15302
Query: 659 WEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
W P DGG + Y+VER+ K QRW+K N + T+ Y+ + + EG YE R+ A NA
Sbjct: 15303 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 15362
Query: 719 IGVSQPSMNTKPFMPIAPT----SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
G+S PS T PF T P + V D + ++ ++ W P G I GY+VE
Sbjct: 15363 AGISAPS-PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVE 15421
Query: 775 YCLEGSEEW-VPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
L +EW + ++ +T+ L R+ +N G EPA + +
Sbjct: 15422 IALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAED 15481
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKG-GAPLDTSRVHVRTSD 892
PP+I L LR+ + L L VP +G+P P+V W + G LD + + TS
Sbjct: 15482 RMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIE-STSS 15540
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVE 952
+ T+ V R DSG+Y L+V+ + +A + +RV++ GPP ++ VKEV T+ +
Sbjct: 15541 Y-TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLT 15599
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W P DG S+I Y V+K + + V TS V L G YYFRV EN
Sbjct: 15600 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEY 15659
Query: 1013 GLSDSPGVSKNTARILK 1029
G+ G+ TA +K
Sbjct: 15660 GI----GLPAETAESVK 15672
Score = 215 bits (548), Expect = 2e-55
Identities = 150/495 (30%), Positives = 223/495 (45%), Gaps = 24/495 (4%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
QEPP + LD S K I ++AG LR+ +TG P P W K E + R I+
Sbjct: 8727 QEPPAVELDVSVK---GGIQIMAGKTLRIPAVVTGRPVPTKVWTK--EEGELDKDRVVID 8781
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S +I+ A R+D GRY I TN G A+ ++V DVP P ++
Sbjct: 8782 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8841
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYESTKMIEGILYEMRVF 714
+L W P DGG +TG+++ERK W + + TE + + T ++EG Y+ RV
Sbjct: 8842 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ---PIETERSKCDITGLLEGQEYKFRVI 8898
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G P + P + P+ P + P L + T +T TL W+ P G I GY
Sbjct: 8899 AKNKFGCG-PPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGY 8957
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
++E ++ N F V+NL FRV VN G SEP +L V I
Sbjct: 8958 IIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-SLPLNVVI 9016
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGA-------PLDT 883
++ PP I+L +R I+ K GE +++ G P P++ W+K L
Sbjct: 9017 QDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQI 9076
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKE 943
++ V S+ T + +A R D G Y ++ + + V ++ PP N+ V +
Sbjct: 9077 TKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9136
Query: 944 VWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIVGNE 1001
+ + + W AP D+G SEI Y + K D +K EW V + LI +
Sbjct: 9137 IKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQ 9196
Query: 1002 YYFRVYTENICGLSD 1016
Y FRV N G+SD
Sbjct: 9197 YEFRVRAVNKYGISD 9211
Score = 213 bits (543), Expect = 6e-55
Identities = 157/584 (26%), Positives = 263/584 (45%), Gaps = 34/584 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
L +K+ E K V V W+K+GVE+ + I+ V L + D + G
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21655
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRL-- 564
YT + S A++ ++KV+ P + I + G K+ L
Sbjct: 21656 VYTVEAKNASGSAKAEI---KVKVQDTPGKVVGPIRF-----------TNITGEKMTLWW 21701
Query: 565 DVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN-- 622
D + P+ ++ ++ T+ IE + + S+ +E ++ + N
Sbjct: 21702 DAPLNDGCAPITHYII-EKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKF 21760
Query: 623 ----PVGED--VASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
P+ D VA I V D P PE IT + L W P DGG + Y++E
Sbjct: 21761 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITG---NSITLTWARPESDGGSEIQQYILE 21817
Query: 677 RKKKGSQRWMK-LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
R++K S RW+K ++ +ET ++ T + EG YE V A NA GV S ++
Sbjct: 21818 RREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE 21877
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
P+ P P + V D + TT +L+W P G I GY++E C +W N E
Sbjct: 21878 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV 21937
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
+ +TV +L G FRV +N AG+ + + + + P++ + + +QT++
Sbjct: 21938 KTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVV 21997
Query: 853 KVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ G + L + +QG+P P VW+K + L + R + T+D + V R+D+G+Y L
Sbjct: 21998 RAGASIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTL 22056
Query: 913 SVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKA 972
+V+ + + T ++V++ GPP + K+V +A + W AP DG + I Y V+K
Sbjct: 22057 TVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKR 22116
Query: 973 DKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + E+ V+DL G YYFRV N G+ +
Sbjct: 22117 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 22160
Score = 213 bits (542), Expect = 8e-55
Identities = 131/391 (33%), Positives = 192/391 (49%), Gaps = 16/391 (4%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PDPPE +T V ++ +VW PP YDGGK +TGY +E+K+K S RW+ +N E
Sbjct: 12027 PDPPE---VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 12083
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
+ ++ Y+ RV A N IG+ +PS+ ++P + PI P P + V D T + TL
Sbjct: 12084 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITL 12143
Query: 756 KWRPPNRIGAGGIDGYLVEYC-----LEGSEEWVPANTEP-VERCGFTVKNLPTGARILF 809
W P G I GY+VE E W N + R FTV +L F
Sbjct: 12144 GWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEF 12203
Query: 810 RVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPR 869
RV N G PA L + + +EI EPP+I L +R+ I + G + L +G+P
Sbjct: 12204 RVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPA 12263
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV 929
P+V W K G + V D + + R DSG+Y L++ + + +RV
Sbjct: 12264 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 12323
Query: 930 VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
++ GP ++ V +V T+ V W P++DG S++ Y V+K + W V + T
Sbjct: 12324 LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKT 12383
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGV 1020
S V++L+ GNEYYFRV N G PGV
Sbjct: 12384 SFHVTNLVPGNEYYFRVTAVNEYG----PGV 12410
Score = 211 bits (538), Expect = 2e-54
Identities = 145/521 (27%), Positives = 236/521 (45%), Gaps = 40/521 (7%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW--------LKGDEVFTT 587
QE P++ +D +++ +V AG+++R+ I G P P ++W D V
Sbjct: 9433 QEEPEVFIDIG---AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDI 9489
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
E ++E + S +I +R G+Y+I N G+ A+ ++V+DVP PP+ +++
Sbjct: 9490 PED-AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKV 9548
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
+ + L W+ P DGG + GY++E++ + W K+N + TT+ ++
Sbjct: 9549 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDC-GSTTFVVPDLLSEQ 9607
Query: 708 LYEMRVFAVNAIGVSQP---SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y RV A N G+ P T PI P P+ L + +T T L W+PP G
Sbjct: 9608 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDG 9667
Query: 765 AGGIDGYLVEYCL------EGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG 818
+ Y+VE CL E W N VE FTV++L G FRV VN AG
Sbjct: 9668 GSPVTHYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAG 9726
Query: 819 RSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
S+P+ P + PP I L + + G +N+V +G P P + W K
Sbjct: 9727 VSKPSATVGPCDCQRPDMPPSIDLKEFMEV----EEGTNVNIVAKIKGVPFPTLTWFK-- 9780
Query: 879 AP----------LDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
AP L + V+ D + Q+ RSD+G Y ++ + +R+
Sbjct: 9781 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9840
Query: 929 VVEKAGPPIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR 987
V+ + GPP+ + + V + W PKDDG S+I Y ++K + W +V +
Sbjct: 9841 VLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPK 9900
Query: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
+ T+ L+ G+EY FR+ +N G+ + TAR L
Sbjct: 9901 ECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 9941
Score = 211 bits (536), Expect = 4e-54
Identities = 160/614 (26%), Positives = 270/614 (43%), Gaps = 45/614 (7%)
Query: 431 ELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHV 489
+L++E +V + +V+ + + +S K T W K+G+ ++ + RI ++
Sbjct: 16853 DLVIEP---DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDS 16909
Query: 490 GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
L I + +D G Y G ++ I++ + K +PPK + +
Sbjct: 16910 LDLTTLSIKETHKDDGGQY-----GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVS 16964
Query: 550 SENAIV-----VVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 604
+E+ + + G + + W +V + T RT ++
Sbjct: 16965 AESITLSWNPPLYTGGCQITNYIVQKRDTTTTVW----DVVSATVARTTLK--------- 17011
Query: 605 IESAQREDEGRYTIKVTNPVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVW 659
+ + E ++ I N G+ A +V P PP T++ +D ++ W
Sbjct: 17012 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 17071
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
P+ +GG PV GY +ERK++ S W K+N + +T +++ + EGI YE RV+A N +
Sbjct: 17072 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 17131
Query: 720 GVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
GV + S N++ ++ P P P ++V+ TL+W P G I GY+VE
Sbjct: 17132 GVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKR 17188
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIA 835
W+ A+ V FTV L R FRV+ N AG S+P+ P+T ++
Sbjct: 17189 DLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEV 17248
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFD 894
E P+I + R T + GE L GKP P + W +G ++ S R ++ +DF
Sbjct: 17249 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17308
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVEW 953
+ V+ A R D G+Y L + + ++V+++ GPP V V V + W
Sbjct: 17309 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 17368
Query: 954 QAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I Y V+K + + W V S V+ L+ GNEY FR+ N G
Sbjct: 17369 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 17428
Query: 1014 ----LSDSPGVSKN 1023
L +P + KN
Sbjct: 17429 VGEPLESAPVLMKN 17442
Score = 210 bits (535), Expect = 5e-54
Identities = 152/568 (26%), Positives = 255/568 (44%), Gaps = 40/568 (7%)
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE 527
T +WYK+ E++ + + + + ++I D + G Y S SA
Sbjct: 20531 TIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT----- 20585
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
I+V+ + K PP ++ T+E +++ PP K
Sbjct: 20586 IRVQILDKPGPPGGPIEFKTVTAEK-------------ITLLWRPPADDGGAKITHYIVE 20632
Query: 588 TEGRTRI------EKRVDCSSFVIESAQ--REDEGRYTIKVTNPVG-----EDVASIFLQ 634
+R+ E +C +I + + + +E + ++ N G E + +
Sbjct: 20633 KRETSRVVWSMVSEHLEEC---IITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKN 20689
Query: 635 VVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT 694
P PP +T + ++ +VW P+ DGG ++GY +E++ K S W K+ E
Sbjct: 20690 AFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR 20749
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDT 751
+T + T + E Y+ RV AVNA G S+PS K PI P P + + D T +
Sbjct: 20750 DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKS 20809
Query: 752 TTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLPTGARILFR 810
+ TL W P G + GY+VE EEW +T+ V + V NL G FR
Sbjct: 20810 SITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFR 20869
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VN AG+ EP + +PV ++I E P+I L LR + I K GE + +++PF+G+P P
Sbjct: 20870 VSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPP 20929
Query: 871 QVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI-ENMKDTATIRIR 928
V W K L + +R + +D ++ + Q R+D+G+Y L+++ ++T+ ++
Sbjct: 20930 TVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVK 20989
Query: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
V++ + VK V + W P DG S I+ Y ++K D W V +
Sbjct: 20990 VLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS 21049
Query: 989 TSCTVSDLIVGNEYYFRVYTENICGLSD 1016
TS + DL ++FRV EN G+ +
Sbjct: 21050 TSFKLIDLSEKTPFFFRVLAENEIGIGE 21077
Score = 209 bits (532), Expect = 1e-53
Identities = 154/579 (26%), Positives = 261/579 (45%), Gaps = 27/579 (4%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK-WYKNGVEVRPSK-RITISHVGRFHKLVIDDVRPEDE 505
+ V A E V + ++ + + W K+G E+ + R+ I + LV+ D D
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G Y LS + I V+ + + PP+ L +G T+E + A N D
Sbjct: 18405 GQYIL-----KLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL--AWNPPLQD 18457
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP-- 623
++ ++ ++ T+ T++ V ++ + +E + + N
Sbjct: 18458 GGAN-----ISHYII-EKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 18511
Query: 624 VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
+GE + S + + P PP ++++ +D ++ W P+ DGG + GY++E++ K
Sbjct: 18512 IGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK 18571
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGV---SQPSMNTKPFMPIAPT 737
RW K N + T+ T + EG YE RV A NA GV S+PS+ + + P
Sbjct: 18572 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP 18631
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-- 795
P + V D + ++ +L W P G + GY+VE ++EW T P G
Sbjct: 18632 GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTC-TPPTGLQGKQ 18690
Query: 796 FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG 855
FTV L FR+ +N G EPATL V +E EPP+I L LR+ + +
Sbjct: 18691 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18750
Query: 856 EQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L L V +G+P P+V W K L T R + + T+ + R DSG Y L+++
Sbjct: 18751 ATLRLFVTIKGRPEPEVKWEKAEGIL-TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 18809
Query: 916 IENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ TA + +RV++ P+N+ ++EV + + W+ P DG ++I Y V+K +
Sbjct: 18810 NNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETT 18869
Query: 976 TMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
+ + T+ + +L G YYFRV N G+
Sbjct: 18870 RKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908
Score = 208 bits (529), Expect = 3e-53
Identities = 149/504 (29%), Positives = 229/504 (45%), Gaps = 42/504 (8%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE 613
I+V+ G KL + V P P +W K + ++ T + V +S R D
Sbjct: 8024 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSV-RADA 8082
Query: 614 GRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGY 673
G YTI + N +G ASI ++V+ +P P + ++ + + + L WEPP +DGG P+ Y
Sbjct: 8083 GIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHY 8142
Query: 674 LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM- 732
++ER++ G + ++ + + ++ +I Y RV AVN +G + P +
Sbjct: 8143 VLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8201
Query: 733 --PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP 790
P P P+ + V + T T+ W+PP G I GY++E +G E W N
Sbjct: 8202 QDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL 8261
Query: 791 VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
V +T K L G FRV N AG SEP+ P + + PK+ LR +
Sbjct: 8262 VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSL 8317
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKG------------GAPLD---------------- 882
K G+++ L G P P + W K APL
Sbjct: 8318 EVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLP 8377
Query: 883 -TSRVHVRTS-DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVM 940
T R+ + S ++ VR + R D G Y + V+ ++ A + V++ GPPIN +
Sbjct: 8378 LTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV 8437
Query: 941 VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIV 998
+++ T+ L +W+ P DDG SEI+ Y ++K D K EW V RH +V+ LI
Sbjct: 8438 FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIE 8497
Query: 999 GNEYYFRVYTENICGLSDSPGVSK 1022
G EY FRV EN G P VSK
Sbjct: 8498 GKEYLFRVRAENRFG-PGPPCVSK 8520
Score = 205 bits (522), Expect = 2e-52
Identities = 154/585 (26%), Positives = 255/585 (43%), Gaps = 40/585 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E + +V + + T +W + E+ S R I + L++ D D G
Sbjct: 17263 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 17322
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A S S +N V+ + + PP+ + +G TSE
Sbjct: 17323 QYILRASNVAGSKSFPVN-----VKVLDRPGPPEGPVQVTGVTSEKC------------- 17364
Query: 567 SITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
S+T PP ++ ++ ++ T+ T + V +S + +E + I
Sbjct: 17365 SLTWSPPLQDGGSDISHYVV-EKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMA 17423
Query: 621 TNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N G E + +P PP+++ +T++ +D + W P DGG + GY+V
Sbjct: 17424 VNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV 17483
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFM 732
E++ + RW+K N T+ T + E YE RV A NA GV +PS T K
Sbjct: 17484 EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD 17543
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW---VPANTE 789
P+ P + + D T + TL W P G I GY+VE C EEW P
Sbjct: 17544 PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17603
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
V R F + L RV +N G E ++ V + E P++ L LR+
Sbjct: 17604 RVTR--FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG 17661
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE 909
+ + G + +PF+G+P P++ W++ T +V + T + R+D+G+
Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGK 17720
Query: 910 YELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFV 969
Y L ++ + +A + ++V++ GPP N+ VKEV +A + W+ P DG +++ Y +
Sbjct: 17721 YILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17780
Query: 970 QKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
K + + NV + TS V +L G YYFRV EN G+
Sbjct: 17781 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 17825
Score = 205 bits (521), Expect = 2e-52
Identities = 150/561 (26%), Positives = 249/561 (44%), Gaps = 34/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W K+G ++ + R+ + L I + +D G YT A + + L+ + ++
Sbjct: 17973 WVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE- 18031
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVF---- 585
K PP + V +++ D V I+ EPP +
Sbjct: 18032 ----KPGPP--------------VGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 18073
Query: 586 -TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVP 639
TTT + V ++ I + E ++ I N G+ D ++ +Q P
Sbjct: 18074 DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 18133
Query: 640 DPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYE 699
PP +TS+ +D ++ W P+ DGG + GY +E+K+K S W+KLN +T ++
Sbjct: 18134 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18193
Query: 700 STKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
+T + EG+ YE +V A N +G+ +PS ++ F+ P P +T TLKW+
Sbjct: 18194 TTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKK 18253
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G I GY+VE W+ A+ V FTV L R FRV+ N AG
Sbjct: 18254 PAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGN 18313
Query: 820 -SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
SEP+ + +T R+ + P L + + GE L +GKP P VVW+K G
Sbjct: 18314 FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDG 18373
Query: 879 APLD--TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
L+ +R+ ++++ T V+ R+D G+Y L + + I ++V+++ GPP
Sbjct: 18374 KELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPP 18433
Query: 937 IN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+ V V + W P DG + I Y ++K + + W V + + V+
Sbjct: 18434 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTK 18493
Query: 996 LIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 18494 LLPGNEYIFRVMAVNKYGIGE 18514
Score = 204 bits (519), Expect = 4e-52
Identities = 159/589 (26%), Positives = 267/589 (45%), Gaps = 45/589 (7%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
LT+KA + V K K W K G ++RPS I+ L I +D
Sbjct: 14016 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDA 14075
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G+YT K+ +++ V VP P ++ S ++E A
Sbjct: 14076 GEYTITATN---PFGTKVEHVKVTVLDVPGPPGP---VEISNVSAEKA------------ 14117
Query: 566 VSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619
++T PP P+ +++ ++ T+ T + + + V + +E + +
Sbjct: 14118 -TLTWTPPLEDGGSPIKSYIL-EKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVS 14175
Query: 620 VTNPVG--EDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL 674
N G E V S +++VD P PPE +++V ++ A + W+ P+ DGG +TGY
Sbjct: 14176 AVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYH 14235
Query: 675 VERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-- 732
VER++K S RW++ ++ + T + EG YE RV A N G+ PS + +
Sbjct: 14236 VERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMK 14295
Query: 733 ----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
P P S P V D T + +L W P+ G I GY+VE+ G E W+ T
Sbjct: 14296 DAAYPPGPPSNPH---VTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTT 14352
Query: 789 EPVERCG-FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
R F V +L T + FR+ +N AG EPA + V I E P L LR
Sbjct: 14353 GTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAELR 14411
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDS 907
+T + + G + + VP +G+P P+V WTK L +R ++ ++ T+ + + R D+
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRYDT 14470
Query: 908 GEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGY 967
G++ ++++ K + + +RV++ GP +N+ ++ + + W P DG S I Y
Sbjct: 14471 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNY 14530
Query: 968 FVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V+K + + + + V+ L G EY+FRV EN G+ +
Sbjct: 14531 IVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14579
Score = 203 bits (517), Expect = 7e-52
Identities = 166/605 (27%), Positives = 260/605 (42%), Gaps = 40/605 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E ++ + + T +W K E+ + R+ I L + D D G
Sbjct: 16181 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16240
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV-----VVAGNK 561
+Y A S +N V+ + + PP+ + SG T+E + + G
Sbjct: 16241 NYILKAKNVAGERSVTVN-----VKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGS 16295
Query: 562 LRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVT 621
++ + W T ++ V S + +E + I
Sbjct: 16296 DIINYIVERRETSRLVW-------------TVVDANVQTLSCKVTKLLEGNEYTFRIMAV 16342
Query: 622 NP--VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
N VGE + S + VPD P+A +T+V +D I+VWE P DGG + GY++E
Sbjct: 16343 NKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLE 16402
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFMP 733
++ K RW + + + E T +IE YE RV A NA G+S+PS + K P
Sbjct: 16403 KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDP 16462
Query: 734 IAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP--V 791
I P + V D+T ++ L W P G I GY+VE C EW T P +
Sbjct: 16463 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMC-TPPTGI 16521
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
+ V+ L FR+ +N AG E A + P+ + E E P I L LR+
Sbjct: 16522 NKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 16581
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
+ G L L VP +G+P P+V W K + + + TS F T + R DSG+Y
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF-TSLVLDNVNRYDSGKYT 16640
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
L+++ + +A + +RV++ PP+N+ V E+ + + W+ P DG S+I Y V+K
Sbjct: 16641 LTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 16700
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
+ + V S + L G YYFRV EN G+ G+ TA +K
Sbjct: 16701 REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI----GLPAQTADPIKVA 16756
Query: 1032 ITFKP 1036
+P
Sbjct: 16757 EVPQP 16761
Score = 203 bits (516), Expect = 9e-52
Identities = 157/575 (27%), Positives = 257/575 (44%), Gaps = 39/575 (6%)
Query: 462 VSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
V D V GK W K E+ +++++ + G+ VI D G YT
Sbjct: 22694 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22753
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
+ K + +KV LD G + + V K L S+ E
Sbjct: 22754 S---GTKAVSVMVKV------------LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA 22798
Query: 576 A-TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
T + T+ +E S+V+ + +E + ++ N G V
Sbjct: 22799 EITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP 22858
Query: 635 VV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLN 689
+V +P PP G++ I+ W P DGG ++ YLV++++K S RW ++N
Sbjct: 22859 IVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVN 22918
Query: 690 FE-VFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
+ V +T + T ++EG Y+ RV AVNA G S+PS + +P P S P
Sbjct: 22919 KDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPR- 22977
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP-VERCGFTVKNL 801
V D T + +L W P G I GY++E + +++W +T + FTV +L
Sbjct: 22978 --VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDL 23035
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G + FRV VN+ G SE + + E E P + L L++T + G L L+
Sbjct: 23036 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM 23095
Query: 862 VPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKD 921
V G+P P + W+K G L SR + T++ ++ V + R D+G+Y + + ++ K
Sbjct: 23096 VSVSGRPPPVITWSKQGIDL-ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23154
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
+AT+ ++V + GP +V VKEV + + W+ P DG + + Y V+K + +
Sbjct: 23155 SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKT 23214
Query: 982 VYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T +S L+ G YYFRV ENI G+ +
Sbjct: 23215 VTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23249
Score = 202 bits (515), Expect = 1e-51
Identities = 126/404 (31%), Positives = 190/404 (47%), Gaps = 12/404 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP P+ ++SV + + WE P YDGG PVTGY +E K S+RW ++N + T
Sbjct: 9944 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 10003
Query: 698 ----YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTD 750
Y+ T +IEG Y+ RV+A+NA GV S+ + P PIAP P + D T
Sbjct: 10004 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVT-DWTK 10062
Query: 751 TTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
++ L+W PP + G + GY+VEY EG EEW + V V L GA FR
Sbjct: 10063 SSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFR 10122
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VNIAG EP + + +++ P ++L +R + G + ++ GKP P
Sbjct: 10123 VRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP 10182
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
V W L + T+ + ++ RS G Y L + E + TI + V+
Sbjct: 10183 TVTWNMNERTL-PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 10241
Query: 931 EKAGP-PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
+ GP + + + + W +P+DDG S I Y ++K + W V
Sbjct: 10242 DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ 10301
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
+ TV LI G Y+FR+ EN G+ P V + A +++ IT
Sbjct: 10302 NATVQGLIQGKAYFFRIAAENSIGM--GPFVETSEALVIREPIT 10343
Score = 201 bits (510), Expect = 4e-51
Identities = 227/907 (25%), Positives = 363/907 (40%), Gaps = 108/907 (11%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V ++ E++ KWF+N + I SSKY+ L I L D A Y
Sbjct: 6278 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6337
Query: 327 EVAVKDE-----KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKD 381
V++ + K L V+E + IV PL+D + V +V+ + W K+
Sbjct: 6338 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6397
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEV 441
G E+ F R ++ D +H+L D D G Y V + AEL++ E E
Sbjct: 6398 GEEVP----FDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEF 6453
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
++ + D TV + AVF C++S EK KWY+NG E++ K+ G H+L+I D R
Sbjct: 6454 VEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCR 6513
Query: 502 PEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
+DE +Y V D + A+L EI VE + PP+ L+ G + + + N
Sbjct: 6514 LDDECEYACGVEDRKS---RARLFVEEIPVEII---RPPQDILEAPG---ADVVFLAELN 6564
Query: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
K +++V V ++GD+ +EG +I + C + D+G Y
Sbjct: 6565 KDKVEVQWLRNNMVV---VQGDKHQMMSEG--KIHRLQIC------DIKPRDQGEYRFIA 6613
Query: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL-VERKK 679
+ A L++ P +I + +D + D GKP+T + +
Sbjct: 6614 K----DKEARAKLELAAAP------KIKTADQDLVV--------DVGKPLTMVVPYDAYP 6655
Query: 680 KGSQRWMKLNFEVFT---ETTYEST--KMIE---GILYEMRVFAVNAIGVSQPSMNTKPF 731
K W K N + T +TT E T +++E G ++ N G ++ +N K
Sbjct: 6656 KAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVI 6715
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
P +L V + D +L W P G I GY+VE + WV A T+
Sbjct: 6716 DVPGPVR---NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLA-TDRA 6771
Query: 792 ERCGFTVKNLPT-GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
E C FTV L G LFRV N G EP PV R + P P ++ T
Sbjct: 6772 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITD 6829
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---FDTVFFVRQAARS-- 905
+ + G L P GGA + + +R +DT VR S
Sbjct: 6830 VNRFGVSLTWEPPEY----------DGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSAT 6879
Query: 906 -----DSGEYELSVQIEN-----MKDTATIRIRV---VEKAGPPINVMVKEVWGTNALVE 952
+ EY V+ +N AT ++V +E+ PP+N+ + ++ ++
Sbjct: 6880 VTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLK 6939
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P DG S I+GY +++ ++ W + + V+ L GN+Y +RV EN
Sbjct: 6940 WEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENK 6999
Query: 1012 CGLSD-SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
G+SD S + TA T +K+ + P +T L+
Sbjct: 7000 AGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPST------------ 7047
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
G+P+P W + + + L I D G YT + N +
Sbjct: 7048 --GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7105
Query: 1131 AECKLEV 1137
E + V
Sbjct: 7106 GEIDVNV 7112
Score = 201 bits (510), Expect = 4e-51
Identities = 147/489 (30%), Positives = 221/489 (45%), Gaps = 29/489 (5%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKR 597
PP++ LD T + I V G +R+ + G P P TW K +V EKR
Sbjct: 11533 PPEVELDV---TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR-------EKR 11582
Query: 598 VDCSSFV------IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVG 651
VD + I+ A R D G+Y I N G S + V+D P P + +++T+V
Sbjct: 11583 VDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11642
Query: 652 EDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
++ + WE P+ +GG +T ++VE +K + W + +V ++ Y
Sbjct: 11643 KENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYF 11700
Query: 712 RVFAVNAIGVSQPSMNTK-PFMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
RV A N +GV P++ TK P + I P EP +L + D T LKWR P+ G
Sbjct: 11701 RVCAENKVGVG-PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 11759
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y VE L+GS++W + ++ + V FRV N G S+ +
Sbjct: 11760 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TE 11818
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-- 885
V ++E + P + L L K G+ + L +GKP P+V WTK D +R
Sbjct: 11819 EVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 11876
Query: 886 -VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEV 944
V + T + F + +A RSD G+Y ++ A + V++K GP N+ + +V
Sbjct: 11877 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDV 11936
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
V W P+DDG EI Y ++K + K M W TV+ LI GNEY F
Sbjct: 11937 SSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIF 11996
Query: 1005 RVYTENICG 1013
RV EN G
Sbjct: 11997 RVRAENKIG 12005
Score = 200 bits (508), Expect = 7e-51
Identities = 148/582 (25%), Positives = 254/582 (43%), Gaps = 35/582 (6%)
Query: 450 VKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
VKA EQ + T W K+G ++ + R+ +S L I + ED G Y
Sbjct: 19034 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19093
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
A S++ + I LD G I V+ + ++I
Sbjct: 19094 ELCVSNSAGSITVPITI---------------IVLDRPGPPGPIRIDEVSCDS----ITI 19134
Query: 569 TGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN 622
+ PP ++ ++ + T+T + + V +S I E ++ + N
Sbjct: 19135 SWNPPEYDGGCQISNYIVEKKETTSTTWHI-VSQAVARTSIKIVRLTTGSEYQFRVCAEN 19193
Query: 623 PVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
G+ S VV P PP ++ + ++ W+ P+ DGG V GY +E
Sbjct: 19194 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19253
Query: 678 KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPT 737
K++ S W K N + +T + + + EG++YE RV+A N G+ + S + +P P
Sbjct: 19254 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19313
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
P V ++T + +LKW P+ G I GY+VE W+ N ++ F
Sbjct: 19314 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19373
Query: 798 VKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGE 856
V L R FRV N A SEP+ P+ +++ EPP++ + R + K GE
Sbjct: 19374 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19433
Query: 857 QLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L + G+P P + W K G + + +R + ++D T+ V+ R D+G+Y L+++
Sbjct: 19434 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLK 19493
Query: 916 IENMKDTATIRIRVVEKAGPPINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
+ + +V++K GPP + + + + W P++DG ++I Y V+K +
Sbjct: 19494 NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET 19553
Query: 975 KTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + TSC V+ L+ GNEY FRV N G+ +
Sbjct: 19554 SHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 19595
Score = 198 bits (504), Expect = 2e-50
Identities = 117/410 (28%), Positives = 204/410 (49%), Gaps = 22/410 (5%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTET- 696
+P PP ++ + + ++ W PP+ +GG P+TGY +E++++GS W +++ T+
Sbjct: 9226 LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9285
Query: 697 ----TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVT 749
+ +++EG+ Y+ R A+NA G+ PS + P + PI P P V+D T
Sbjct: 9286 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 9345
Query: 750 DTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP---VERCGFTVKNLPTGAR 806
++ +L W+PP + G I GY+VE EG+ +W N EP + C V NL +
Sbjct: 9346 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVN-EPDKLITTCECVVPNLKELRK 9404
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
FRV VN AG SEP+ + +I E P++ + + + K G Q+ + +G
Sbjct: 9405 YRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG 9464
Query: 867 KPRPQVVWTKGGAPLDTSR--VH-------VRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+P P+ W G + VH + T++ +V + + RS +G+Y ++ + +
Sbjct: 9465 RPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNK 9524
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ TA R++V++ GPP ++ V ++ + + W+ P DDG I GY ++K
Sbjct: 9525 AGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK 9584
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS-PGVSKNTAR 1026
W V T+ V DL+ +Y+FRV EN G+ + + TAR
Sbjct: 9585 AWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR 9634
Score = 198 bits (503), Expect = 3e-50
Identities = 169/622 (27%), Positives = 268/622 (43%), Gaps = 40/622 (6%)
Query: 430 AELIVEEKQLEVLQDIADLT-----VKASEQAVFKCEVSDE---KVTGKWYKNGVEVRPS 481
+ +I++E Q+E D+ +T KA +S KVT W + ++ +
Sbjct: 22262 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT--WKLEEMRLKET 22319
Query: 482 KRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKI 541
R++I+ L + D D G Y L +A + + V + + P
Sbjct: 22320 DRVSITTTKDRTTLTVKDSMRGDSGRYFLT-----LENTAGVKTFSVTVVVIGRPGPVTG 22374
Query: 542 HLDCSGKTSENAIVVVAGNKLRLDVSITG------EPPPVATWLKGDEVFTTTEGRTRIE 595
++ S ++E+ ++ K IT E A L V T T +
Sbjct: 22375 PIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22434
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
K ++ S F + S R V+ P+ E I P P + V +
Sbjct: 22435 KYMEYS-FRVSSENR-------FGVSKPL-ESAPIIAEHPFVPPSAPTRPEVYHVSANAM 22485
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WE P +DGG + GY VE+K++ + W+K N E Y+ T ++EG+ Y+ R +A
Sbjct: 22486 SIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYA 22545
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE- 774
+NA GVS+ S ++P M P P V DVT +T +L W P G + GY++E
Sbjct: 22546 LNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIER 22605
Query: 775 --YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSEPATLAQPVTI 831
G W+ N V FTV L G FRV+ N AG S+ + PVT
Sbjct: 22606 KPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTC 22665
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVR 889
R+ PPK L L + + G L L GKP P+++WTKG LD +V ++
Sbjct: 22666 RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQ 22725
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
+ ++ RSDSG+Y L+V+ + ++ ++V++ GP + V V
Sbjct: 22726 YTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKC 22785
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W P++DG +EI Y V++ + + W V S V+ LI NEY FRV
Sbjct: 22786 TLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22845
Query: 1010 NICG----LSDSPGVSKNTARI 1027
N G + P V++N+ I
Sbjct: 22846 NKYGPGVPVESEPIVARNSFTI 22867
Score = 197 bits (501), Expect = 5e-50
Identities = 164/594 (27%), Positives = 258/594 (43%), Gaps = 46/594 (7%)
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKL 495
L+ + DL A E + F+ ++ + GK W K + R+++ L
Sbjct: 13612 LKGLPDLCYLAKENSNFRLKIP---IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 13668
Query: 496 VIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV 555
++ D + D G YT A K + IKV V K P + T+E
Sbjct: 13669 IVYDCQKSDAGKYTITLKNVA---GTKEGTISIKV--VGKPGIPTGPIKFDEVTAEA--- 13720
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKGDEVFT-TTEGRTRIEKR-VDCSSFVIESA---QR 610
+++ PP G E+ E R + + V C+S V ++ R
Sbjct: 13721 ----------MTLKWAPPKDDG---GSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 13767
Query: 611 EDEG-RYTIKVTNP----VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPP 662
EG YT +V+ VGE + S + DVPD P I V D L W P
Sbjct: 13768 LHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDP 13827
Query: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
GG P+TGY +E K++ S W + N ++ T + EG+ YE RV A+N GV
Sbjct: 13828 KKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVG 13887
Query: 723 QPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+PS+ ++P + + P P V ++T + TL W P G + GY+VE S+
Sbjct: 13888 KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS 13947
Query: 783 WVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIR 841
W+ AN V C FTV +L G + FR+ N AG S P+ + + ++ E P I
Sbjct: 13948 WMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIV 14007
Query: 842 LPRHLRQTYIRKVGEQLNL-VVPFQGKPRPQVVWTKGGAPLDTSRV-HVRTSDFDTVFFV 899
L ++ K G+ + L + GKP P+ W+K G + S + + ++ ++ +
Sbjct: 14008 LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTI 14067
Query: 900 RQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
+ A R D+GEY ++ +++ V++ GPP V + V A + W P +D
Sbjct: 14068 KYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLED 14127
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
G S I Y ++K + + W V E + + LI GNEY FRV N G
Sbjct: 14128 GGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14181
Score = 192 bits (489), Expect = 1e-48
Identities = 116/380 (30%), Positives = 190/380 (50%), Gaps = 8/380 (2%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP A+ + V + L WEPP DGG+P+ Y++E+K++ RW+K + +
Sbjct: 7812 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7871
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T +IEG + +V A N GV PS T+ P +P S PL L V D +
Sbjct: 7872 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7931
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTV-KNLPTGARILFRVVGV 814
W+PP + G I GY VE C G+E+W+ N+ P++ F V + + + RV V
Sbjct: 7932 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 7991
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
N G SEP+ +++ V ++ P I L H I GE+L++ VPF+ P P V W
Sbjct: 7992 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 8048
Query: 875 TKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKA 933
K G + S R+ ++ V ++ R+D+G Y ++++ + TA+I ++V+
Sbjct: 8049 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 8108
Query: 934 GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTV 993
GP ++ ++ ++ + W+ P+ DG + I+ Y +++ + + V S TV
Sbjct: 8109 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 8168
Query: 994 SDLIVGNEYYFRVYTENICG 1013
DLI EY+FRV N G
Sbjct: 8169 KDLIPNGEYFFRVKAVNKVG 8188
Score = 191 bits (485), Expect = 3e-48
Identities = 127/440 (28%), Positives = 205/440 (46%), Gaps = 10/440 (2%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVPD 640
T+T T + V + + +E ++ IK N G D A + +++ P
Sbjct: 20240 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPG 20299
Query: 641 PPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYES 700
PP +T+V + + W P+ +GG V GY +E K + S W K N V T ++
Sbjct: 20300 PPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKV 20359
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPP 760
T + G++YE RV+A NA GV +PS ++P + I P ++ + D++ + +L W+ P
Sbjct: 20360 TTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQP 20419
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR- 819
G I GY+VE W A+ V F + L ++ FRV N G
Sbjct: 20420 AFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSI 20479
Query: 820 SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA 879
S P+ + P+T + P I LP + + G + L GKP P + W K
Sbjct: 20480 SNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDK 20539
Query: 880 PLDTSRVHV--RTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPI 937
L T+ + T+D ++ ++ A R +SG YEL ++ +ATIR+++++K GPP
Sbjct: 20540 ELQTNALVCVENTTDLASI-LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPG 20598
Query: 938 N-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ K V + W+ P DDG ++I Y V+K + + W V E T + +
Sbjct: 20599 GPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI 20658
Query: 997 IVGNEYYFRVYTENICGLSD 1016
I GNEY FRV N G+ +
Sbjct: 20659 IKGNEYIFRVRAVNKYGIGE 20678
Score = 189 bits (480), Expect = 1e-47
Identities = 117/378 (30%), Positives = 174/378 (46%), Gaps = 7/378 (1%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PD P+ + V + ++ W P D G P+ GY +E+++ S W ++N +
Sbjct: 8531 PDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKA 8589
Query: 699 ESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTL 755
++EG+ Y RV A NA G S PS PI+P P+ + D + TT L
Sbjct: 8590 NVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVT-DTSSTTIEL 8648
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W PP G G I GY V+ L G+ EW + ++ +TVK + GA RV VN
Sbjct: 8649 EWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVN 8708
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
AG P QPVT+ E EPP + L ++ G+ L + G+P P VWT
Sbjct: 8709 AAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWT 8767
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K LD RV + + ++ A R D G Y ++ A R+ V + GP
Sbjct: 8768 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGP 8827
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+++ L+ W P+DDG SEI G+ +++ D K W E R + C ++
Sbjct: 8828 VLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER-SKCDITG 8886
Query: 996 LIVGNEYYFRVYTENICG 1013
L+ G EY FRV +N G
Sbjct: 8887 LLEGQEYKFRVIAKNKFG 8904
Score = 171 bits (432), Expect = 5e-42
Identities = 168/618 (27%), Positives = 263/618 (42%), Gaps = 61/618 (9%)
Query: 429 EAELIVEEKQLEVLQDI---ADLTVKASEQAVFKCEVS---DEKVTGKWYKNGVEVRPSK 482
E + + ++ E+ D+ A LTVKA + V+ + K+T W K + ++ K
Sbjct: 7306 EIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDK 7363
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
RITI +V + + I D + D G Y A+++ + + ++V + K PP
Sbjct: 7364 RITIENVPKKSTVTIVDSKRSDTGTYII----EAVNVCGRATAV-VEVNVLDKPGPPAA- 7417
Query: 543 LDCSGKTSENAIVV------VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
D + T+E+ ++ G+K+ + + W K T + + K
Sbjct: 7418 FDITDVTNESCLLTWNPPRDDGGSKI-TNYVVERRATDSEVWHKLSS--TVKDTNFKATK 7474
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ A G V PV + Q D P PP + + + +D
Sbjct: 7475 LIPNKEYIFRVAAENMYG-----VGEPVQASPITAKYQ-FDPPGPPTRLEPSDITKDAVT 7528
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W P DGG P+TGY VER + +W++ N +TTY + Y RV A
Sbjct: 7529 LTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAE 7588
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G +PS +T+P + PI P P V+DV T+ L W P G I+ Y++
Sbjct: 7589 NLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVI 7648
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E G++EWV E V + L G FRV VN AG SEP+ + PV RE
Sbjct: 7649 EMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCRE 7707
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKP------RPQVVWTKGGAPLDT-- 883
PP PR L I K L VP + G P + V KG +DT
Sbjct: 7708 KLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTV 7765
Query: 884 --SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRVVEKAGPPIN 938
++ V +++ R AA + G+ + + +IE+ KDT T GPP
Sbjct: 7766 KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYT-EIEDSVLAKDTFT-------TPGPPYA 7817
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT--VSDL 996
+ V +V + ++W+ PK+DG I Y ++K ++ W + C V+D+
Sbjct: 7818 LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKA-GKTAGPDCNFRVTDV 7876
Query: 997 IVGNEYYFRVYTENICGL 1014
I G E F+V EN G+
Sbjct: 7877 IEGTEVQFQVRAENEAGV 7894
Score = 169 bits (427), Expect = 2e-41
Identities = 134/515 (26%), Positives = 221/515 (42%), Gaps = 40/515 (7%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
+ +++ D+T K E A C++ + KWY+ G E+ S++ +S GR H L +
Sbjct: 24163 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24222
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
EDEG YT + + L Q P+ H G + G
Sbjct: 24223 EEQEDEGVYTCIATNEVGEVETSSKLL--------LQATPQFH---PGYPLKEKYYGAVG 24271
Query: 560 NKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE-GRYTI 618
+ LRL V G P P TW G ++ +E T IE + V+++ QR+ G+Y +
Sbjct: 24272 STLRLHVMYIGRPVPAMTWFHGQKLLQNSENIT-IENTEHYTHLVMKNVQRKTHAGKYKV 24330
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
+++N G A + +++ D PD P + I ++ ++ A++ W+PP DGG +T Y+VE+
Sbjct: 24331 QLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 24390
Query: 678 -KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP----------SM 726
+ K W ++ + + TT + E Y RV A N G+S P S
Sbjct: 24391 CEAKEGAEWQLVSSAI-SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24449
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
KP P PT + VT + + W+PP G I Y +E + +W+
Sbjct: 24450 FEKPGAPGKPT-------ITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISV 24502
Query: 787 NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHL 846
TE + F+VKNL G FRV N+ G SE + +++P+T + L
Sbjct: 24503 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 24562
Query: 847 RQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF---FVRQAA 903
R +R LV G P+P V W + G + + R +F + +
Sbjct: 24563 RNLNVR-YQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVT 24621
Query: 904 RSDSGEYELSV--QIENMKDTATIRIRVVEKAGPP 936
D+ Y++ Q ++ TA++ + V K P
Sbjct: 24622 DDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP 24656
Score = 156 bits (395), Expect = 9e-38
Identities = 95/314 (30%), Positives = 153/314 (48%), Gaps = 13/314 (4%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V + + PP+I L + K+ + V AG + LD ++ G+P P +W K + E
Sbjct: 12912 VTILAENVPPRIDLSVAMKS---LLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE 12968
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
G +R C + + S R+D G YTI N G A+I L+V+D P PP +V+I
Sbjct: 12969 GIKMAMQRNLC-TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINK 13027
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ D A+L WEPP+ DGG +T Y+V++++ W +++ V T+ K+IEG Y
Sbjct: 13028 MYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEY 13086
Query: 710 EMRVFAVNAIGV-----SQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
+ R+ A N GV ++P++ P+ P P ++ ++T T+ W+PP G
Sbjct: 13087 QFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP---VISNITKDHMTVSWKPPADDG 13143
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I GYL+E + W N +P+ L G FRV +N AG +P+
Sbjct: 13144 GSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13203
Query: 825 LAQPVTIREIAEPP 838
++ R+ PP
Sbjct: 13204 ASKAAYARDPQYPP 13217
Score = 154 bits (388), Expect = 6e-37
Identities = 221/934 (23%), Positives = 348/934 (37%), Gaps = 146/934 (15%)
Query: 271 GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV 330
G + + E++ + ++W +N + K+ + GK L I D Y
Sbjct: 6554 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 6613
Query: 331 KDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSE-EGAQVMWMKDGVELTRE- 388
KD++ +L + P I T +D V VG + M V A+ W K+ L+ +
Sbjct: 6614 KDKEARAKLELAAAPK-IKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT 6672
Query: 389 -DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
D+ + F+ + + D+GRY+++ +AE + K ++V + +
Sbjct: 6673 IDTTAEQTSFR---------ILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRN 6723
Query: 448 LTVKASEQAVFKCEVS---DEKVT---GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
L V + F EVS +E +T K VE R KR T ++ D
Sbjct: 6724 LEVTET----FDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTW--------VLATDRA 6771
Query: 502 PEDEGDYTFVPDG---YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA 558
E T + G Y +SA+ + + D G I V
Sbjct: 6772 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN 6831
Query: 559 GNKLRLDVSITGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
R VS+T EPP + ++ T+ T + R + S +
Sbjct: 6832 ----RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQ 6887
Query: 613 EGRYTIKVTNPVG---EDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDG 666
E + ++ N +G A+ F++V D P PP + + + L WEPP+ DG
Sbjct: 6888 EYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDG 6947
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSM 726
G P+ GY++ER ++G W++ N ++ E TY+ T + +G Y RV A N GVS PS
Sbjct: 6948 GSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 7007
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
P EP D++ L+ PN I VP+
Sbjct: 7008 ILGPLTADDAFVEP----TMDLSAFKDGLEVIVPNPITI-----------------LVPS 7046
Query: 787 N--TEPVERCGFTVKNLPTGARILFRVVG------VNIAGRSEPA-----------TLAQ 827
P F K L TG R+ + + ++ + RS+ T++
Sbjct: 7047 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7106
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD----- 882
+ + IA P P+ L+ I K L P GG+PL
Sbjct: 7107 EIDVNVIARPSA---PKELKFGDITKDSVHLTWEPPDDD----------GGSPLTGYVVE 7153
Query: 883 ----TSRVHVRTSDFDT-------------VFFVRQAARSDSGEYELSVQIE--NMKDTA 923
+ + + DF T + + AR+ G E + E NM A
Sbjct: 7154 KREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPA 7213
Query: 924 TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
T+ PP NV ++ + + W PK+DG S I GY V++ + + +W
Sbjct: 7214 TV-------PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 7266
Query: 984 ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
E T V+ L G Y +RV N G S S+ T I P +
Sbjct: 7267 EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRPTEEIQAVDTQEAP------E 7317
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+ K L L V AG L V G P+PK+ W K M +++D + I N
Sbjct: 7318 IFLDVKLLAGL---TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7374
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
T+ I D GTY AVN G A A ++ V
Sbjct: 7375 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 152 bits (385), Expect = 1e-36
Identities = 103/305 (33%), Positives = 150/305 (49%), Gaps = 8/305 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
E P I LD T ++ + + AG+ + L+ +SI G+P P ++W K + ++ T+I
Sbjct: 14002 EAPTIVLD---PTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSD-ITQIT 14057
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S I+ A R+D G YTI TNP G V + + V+DVP PP V I++V + A
Sbjct: 14058 STPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKA 14117
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L W PP+ DGG P+ Y++E+++ W ++ E + +TK+I+G Y RV A
Sbjct: 14118 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQGNEYIFRVSA 14176
Query: 716 VNAIGVSQP--SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
VN G +P S K P P V +VT T T+ W+ P G I GY V
Sbjct: 14177 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14236
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E + S WV A PV V L G+ FRV N AG P+ + V +++
Sbjct: 14237 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14296
Query: 834 IAEPP 838
A PP
Sbjct: 14297 AAYPP 14301
Score = 150 bits (378), Expect = 9e-36
Identities = 188/818 (22%), Positives = 320/818 (39%), Gaps = 114/818 (13%)
Query: 277 MVEISDPDLTLKWFK----NGQEI-------KPSSKYVFENVGKKRI----LTINKCTLA 321
++ IS +TL+W K G+EI + S ++ K+RI TI A
Sbjct: 24067 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24126
Query: 322 DDAAYEVAVKDEKCF-----------TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-V 369
+ + V ++E T+L E P I ++D +G+ +++ + V
Sbjct: 24127 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKEMKDVTTKLGEAAQLSCQIV 24185
Query: 370 SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCE 429
+ W + G EL + +Y+ DG+ H L QED G Y I E
Sbjct: 24186 GRPLPDIKWYRFGKELIQS----RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24241
Query: 430 AE-----LIVEEKQLEVLQDIADLTVKA--SEQAVFKCEVSDEKVTGKWYKNGVEVRPSK 482
E L+ Q + + A S + + W+ ++ S+
Sbjct: 24242 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24301
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
ITI + + LV+ +V+ + Y + LS ++ ++ + +P K
Sbjct: 24302 NITIENTEHYTHLVMKNVQRKTHAGK------YKVQLSNVFGTVDAILDVEIQDKPDK-- 24353
Query: 543 LDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKGDEVFTTTEGRTRIEKRVDC 600
IV+ A L+ I+ +PP +W+ + V E + E ++
Sbjct: 24354 -------PTGPIVIEA--LLKNSAVISWKPPADDGGSWIT-NYVVEKCEAKEGAEWQLVS 24403
Query: 601 SSFVIESAQ----REDEGRY-------TIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
S+ + + + E+ G Y T +++P+ I + P P IT+
Sbjct: 24404 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 24463
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
V +D ++ W+PP DGG + Y +E+++K +W+ + E ET + +IEG+ Y
Sbjct: 24464 VTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEY 24523
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPT--------SEPLHLIVEDVTDTTTTLK----- 756
E RV N G S+ S ++P P + E +L V ++ T K
Sbjct: 24524 EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHP 24583
Query: 757 ------WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
+R I A G+ Y ++ G + + A+ + + V+ G +
Sbjct: 24584 KPIVKWYRQGKEIIADGLK-YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSV--- 24639
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV--GEQLNLVVPFQGKP 868
S A+L E+ P KI LP+ L GE +++ +PF GKP
Sbjct: 24640 ---------SGTASL-------EVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 24683
Query: 869 RPQVVWTKGGAPLDTSRVH--VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
P + W KG +D + + + T F ++ F R D+G Y + + D T+
Sbjct: 24684 DPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE 24743
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
+ V + PP V V +V + + W P DG S+I Y V+K W V +
Sbjct: 24744 LDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA- 24802
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNT 1024
R T TV +L Y FRV EN GLS S+ T
Sbjct: 24803 RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 24840
Score = 149 bits (375), Expect = 2e-35
Identities = 110/360 (30%), Positives = 159/360 (44%), Gaps = 37/360 (10%)
Query: 268 VDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYE 327
V G E+S D+ ++W+ G++++PS K V + GK LT+ L D +
Sbjct: 5835 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5894
Query: 328 VAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTR 387
+ KD K LFVKEPPV PLEDQ V G + EVS E A+V W K+G E+ +
Sbjct: 5895 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 5954
Query: 388 EDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
+Y DG+ L+ D ED Y + L V +E L+ + D
Sbjct: 5955 ----SKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTD 6010
Query: 448 LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGD 507
L V+ E A F+CE+S E KW+K+G E++ K+ I G LVI+ +DE +
Sbjct: 6011 LQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAE 6070
Query: 508 YTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVS 567
Y+ + S L LE + + + + SE + KL +VS
Sbjct: 6071 YSC--EVRTARTSGMLTVLEEEAVFTKNL--------ANIEVSETDTI-----KLVCEVS 6115
Query: 568 ITGEPPPVATWLKGDEVF-------TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
+P W KGDE TEGR RI VI++A ED G Y ++
Sbjct: 6116 ---KPGAEVIWYKGDEEIIETGRYEILTEGRKRI--------LVIQNAHLEDAGNYNCRL 6164
Score = 149 bits (375), Expect = 2e-35
Identities = 101/318 (31%), Positives = 146/318 (45%), Gaps = 14/318 (4%)
Query: 528 IKVEYVPKQEP---PKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKG-DE 583
+K E V +E P + L SG + V AG+ +RL+ + G+P P W K D
Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSG-----VLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDA 11869
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
T R +I+ R D S F + A+R D G+Y + TN G VA + V+D P P
Sbjct: 11870 TDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVR 11929
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++I V D + W+PP DGG + Y++E+ + W + V T T T++
Sbjct: 11930 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT-TVTRL 11988
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT---TTLKWRPP 760
IEG Y RV A N IG P+ +KP + +P +VT + T+ W PP
Sbjct: 11989 IEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPP 12047
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS 820
G I GY +E + S WVP N + V+NL FRV N G
Sbjct: 12048 EYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIG 12107
Query: 821 EPATLAQPVTIREIAEPP 838
EP+ ++PV ++ EPP
Sbjct: 12108 EPSLPSRPVVAKDPIEPP 12125
Score = 145 bits (366), Expect = 2e-34
Identities = 135/522 (25%), Positives = 214/522 (40%), Gaps = 46/522 (8%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP + VG+ L W P +DGG + Y++E K G+ W+++ V T
Sbjct: 7609 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPT- 7667
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTT 752
T + ++EG Y RV AVN G S+PS + P + + P S P L V ++T T
Sbjct: 7668 TQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7727
Query: 753 TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVV 812
LKW P + G I Y+VE + W +T V+ TV L G+ +FRV
Sbjct: 7728 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVA 7786
Query: 813 GVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKPRP 870
N G+S+ + V ++ P P L + K L P G+P
Sbjct: 7787 AENAIGQSDYTEIEDSVLAKDTFTTPGP--PYALAVVDVTKRHVDLKWEPPKNDGGRPIQ 7844
Query: 871 QVV----------WTKGG---APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ V W K G P RV + F VR + G +I
Sbjct: 7845 RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 7904
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+++D + PP+++ V + + + W+ P+ +G S I+GY V+ T
Sbjct: 7905 SIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTE 7957
Query: 978 EWFNVYERN-RHTSCTVSDLIVGN-EYYFRVYTENICGLSDSPGVSKNTARILKTGITFK 1035
+W V R + V + +V + EY RV N G+S+ +S+N + K
Sbjct: 7958 KWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV--VAKDPDCKP 8015
Query: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
+ + HD +V+ G ++ R P P V W K+ E++ +
Sbjct: 8016 TIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8062
Query: 1096 ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N L + + DAG YT N+LG A A ++V
Sbjct: 8063 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 137 bits (345), Expect = 6e-32
Identities = 141/569 (24%), Positives = 234/569 (41%), Gaps = 50/569 (8%)
Query: 68 DAVVVAKVNGKELPDKPTIKWFKGKWL----ELGSKSG--ARFSFKESHNSASNVY---T 118
+ V A+V GK+ + + + K++ + K G A F + SH V+
Sbjct: 5179 EGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKND 5238
Query: 119 VELHIGKVVL--GDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKS 176
+LH + VL + ++LE+K D V+ A + LE+ + K
Sbjct: 5239 AKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLH 5298
Query: 177 D-TAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGI 235
D TA E D L K EV ++ K KD +++ P+ G ++ K A
Sbjct: 5299 DKTAVEKDEITL--KCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKA----- 5351
Query: 236 TDLRGMLKRL-----KKAKVEVKKSAAFTKKLDPAYQVDR--GNKIKLMVEISDPDLTLK 288
DL+ + + K K V A K P Y V+ G +E+S+PD+ +
Sbjct: 5352 -DLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ 5410
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLI 348
W GQ + S GKK IL ++ C L + K L VKE P++
Sbjct: 5411 WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIF 5470
Query: 349 VTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIF 408
+TPL D +VF D + EVS E W+K E+T +D R+ KDG +H ++
Sbjct: 5471 ITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDD----RFELIKDGTKHSMVI 5526
Query: 409 SDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVT 468
ED +Y +LI+E +L+ L + D+T K E AVF E+S + +
Sbjct: 5527 KSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIR 5586
Query: 469 GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEI 528
KW+KN + ++ +++ G+ H + D+ +D + +S AKL LE
Sbjct: 5587 VKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRV--EAMGMSSEAKLTVLEG 5644
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+ K + D +G + I L I+ PV + G E+ +
Sbjct: 5645 DPYFTGKLQ------DYTGVEKDEVI---------LQCEISKADAPVKWFKDGKEIKPSK 5689
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYT 617
+ + + +++ A + D G+YT
Sbjct: 5690 NAVIKADGKK--RMLILKKALKSDIGQYT 5716
Score = 136 bits (342), Expect = 1e-31
Identities = 97/354 (27%), Positives = 155/354 (43%), Gaps = 30/354 (8%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ IVV AG L+ I G+P P W K + T R I+ + ++ V++ R
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKP 669
D G+Y +K++N G I ++V+D P PPE +++T V + L W PP+ DGG
Sbjct: 18402 TDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGAN 18461
Query: 670 VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMN-- 727
++ Y++E+++ W +++ EV Y+ TK++ G Y RV AVN G+ +P +
Sbjct: 18462 ISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGP 18520
Query: 728 ---TKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
P+ P P S P V +T + + W P G I+GY++E + W
Sbjct: 18521 VTACNPYKPPGPPSTPE---VSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18577
Query: 785 PANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N + + V L G FRV N AG EP+ + + PP
Sbjct: 18578 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP------ 18631
Query: 845 HLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVRTSDFD 894
G N V + + W+K GGAP+ V V+ + D
Sbjct: 18632 ----------GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 18675
Score = 134 bits (338), Expect = 4e-31
Identities = 118/428 (27%), Positives = 186/428 (43%), Gaps = 39/428 (9%)
Query: 430 AELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKW----YKNGVEV-RPSKRI 484
+E +V + + V + DL VK EV+ VT W Y G E+
Sbjct: 10333 SEALVIREPITVPERPEDLEVK---------EVTKNTVTLTWNPPKYDGGSEIINYVLES 10383
Query: 485 TISHVGRFHKLVIDD-------VRPEDEGD-YTFVPDGYALSLSAKLNFLEIKVEYVPKQ 536
+ +FHK+ D+ V+ EGD Y + + K +F + +
Sbjct: 10384 RLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDEL 10443
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
PP +HLD K + + G L +G+P P +W K DE + RT I+
Sbjct: 10444 APPTLHLDFRDK-----LTIRVGEAFALTGRYSGKPKPKVSWFK-DEADVLEDDRTHIKT 10497
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWA 655
+ A+R D G+Y + V N G + VVD P PP V V +D+
Sbjct: 10498 TPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM 10557
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
++ W+PP+ DGG +T Y++E+K+ G WM + +TT + +K++EG Y R+ A
Sbjct: 10558 VISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT-SASAKTTCKVSKLLEGKDYIFRIHA 10616
Query: 716 VNAIGVSQP----SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
N G+S P SM K + P IV +VT + + W P+ G I Y
Sbjct: 10617 ENLYGISDPLVSDSMKAKDRFRV--PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNY 10673
Query: 772 LVEYCLEGSEEWVPANTEPVE-RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
++E S+ W +P+ F V +L G + FRV N G +P+ ++PV
Sbjct: 10674 ILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVF 10733
Query: 831 IRE-IAEP 837
++ IA+P
Sbjct: 10734 AKDPIAKP 10741
Score = 130 bits (326), Expect = 9e-30
Identities = 119/457 (26%), Positives = 183/457 (40%), Gaps = 38/457 (8%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K G ++ SKR I+ +LVI + D G Y V + K +++++
Sbjct: 23797 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN---KCGKKAVYIKVR 23851
Query: 530 VEYVPKQEPPKIHLDC----SGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
V P + D S + S G + L + P A W
Sbjct: 23852 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI-LGYILERREVPKAAWYT----- 23905
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN------PVGEDVASIFLQVVDVP 639
I+ RV +S V++ + E + + N P+ + ++ P
Sbjct: 23906 --------IDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP 23957
Query: 640 DPPE-AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
+PP + V + L W P DGG VTGY +ERK+ + +W++ N T T Y
Sbjct: 23958 EPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 24017
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T ++ Y+ R+ A N +G+S+ S ++P + P S+P L + ++ + TL
Sbjct: 24018 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTL 24077
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W P G I GY VEY G W +N E ++ FT+ L FRV N
Sbjct: 24078 QWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAEN 24137
Query: 816 IAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
G S P A + T E P IR + K+GE L G+P P + W
Sbjct: 24138 ETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTKLGEAAQLSCQIVGRPLPDIKW 24194
Query: 875 TKGGAPLDTSRVHVRTSDFDT-VFFVRQAARSDSGEY 910
+ G L SR + +SD T V + D G Y
Sbjct: 24195 YRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24231
Score = 126 bits (316), Expect = 1e-28
Identities = 97/360 (26%), Positives = 157/360 (43%), Gaps = 24/360 (6%)
Query: 258 FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINK 317
FT KL V++ +++ L EIS D +KWFK+G+EIKPS V + GKKR+L + K
Sbjct: 5648 FTGKLQDYTGVEK-DEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKK 5706
Query: 318 CTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM 377
+D Y +K +L +++ + +V PL +V + E+SE+
Sbjct: 5707 ALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHAN 5766
Query: 378 WMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
W G L + + K++GK H L+ + + G + A L V+ +
Sbjct: 5767 WKLKGEALLQTPDCE----IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPR 5822
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVI 497
+ +L+ + D+TV A E A F CE+S E + +WY G ++ PS ++ G+ H L +
Sbjct: 5823 VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTL 5882
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
DV+ ED G+ + A L E VE+ E + E A V
Sbjct: 5883 RDVKLEDAGEVQLTAKDF--KTHANLFVKEPPVEFTKPLEDQTV--------EEGATAV- 5931
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
L+ ++ E V + G E+ + + + RV VI ED YT
Sbjct: 5932 ------LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRV--RKLVIHDCTPEDIKTYT 5983
Score = 126 bits (316), Expect = 1e-28
Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 33/335 (9%)
Query: 526 LEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
L + V + PP I L S + + I V AG + + +TG P P W K + V
Sbjct: 9010 LPLNVVIQDDEVPPTIKLRLSVRG--DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVI 9067
Query: 586 T--------TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVD 637
T E +R E + + S I A RED+G YT+ +N +G ++ ++V D
Sbjct: 9068 EKPTDALQITKEEVSRSEAKTELS---IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYD 9124
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
P PP + +T + + L W+ P+ +GG +T Y+++++ + K +E T T
Sbjct: 9125 RPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRK---KAEWEEVTNTA 9181
Query: 698 YEST----KMIEGILYEMRVFAVNAIGVSQPSMNTK-----PFMPIAPTSEPLHLIVEDV 748
E K+I YE RV AVN G+S + K P+ P +P L
Sbjct: 9182 VEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---R 9238
Query: 749 TDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-----FTVKNLPT 803
T + + W PP G I GY +E EGS W + P+ + G F V L
Sbjct: 9239 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9298
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
G + FR + +N AG P+ + P + PP
Sbjct: 9299 GVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPP 9333
Score = 124 bits (311), Expect = 5e-28
Identities = 98/378 (25%), Positives = 161/378 (42%), Gaps = 25/378 (6%)
Query: 274 IKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE 333
I V ++ ++ KW KNG EIK + K L I D A Y
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 334 KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKA 393
L+V+ + ++D +V R EVSE V WMKD EL D
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITD---- 3055
Query: 394 RYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKAS 453
R + +K+ H L+ D G+Y V+ G A+L VE + + + ++ V
Sbjct: 3056 RIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3115
Query: 454 EQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFV 511
++AV + EV+++ V WYK+G+E+ + +V R H++ I + R D G+YTFV
Sbjct: 3116 QRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV 3175
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
S++ YV EPP++ + + V +G R I+G
Sbjct: 3176 AGRNRSSVTL----------YVNAPEPPQVLQEL------QPVTVQSGKPARFCAVISGR 3219
Query: 572 PPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG--EDVA 629
P P +W K +++ +T + + + +IE A ED YT + N G A
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE-AFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 630 SIFLQVVDVPDPPEAVRI 647
S+ ++V +V P + + +
Sbjct: 3279 SLSVEVPEVVSPDQEMPV 3296
Score = 124 bits (310), Expect = 7e-28
Identities = 96/374 (25%), Positives = 160/374 (42%), Gaps = 24/374 (6%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
QV + E+S + +KWFK+G EIK KY + G RIL INKC L D+A Y
Sbjct: 6012 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6071
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
V+ + L V E + L + +V D +++ EVS+ GA+V+W K E+
Sbjct: 6072 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6131
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
RY +G++ IL+ + ED G Y + + ++ V E E +
Sbjct: 6132 E----TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQ 6187
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+L + E+A F C +S E +W ++ + + + G+ LV+ D +D G
Sbjct: 6188 NLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMG 6247
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y + A +A L +E VP ++ + E VV +V
Sbjct: 6248 TYVVMVG--AARAAAHLTVIEKLRIVVPLKDT---------RVKEQQEVV-----FNCEV 6291
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
+ G A W + +E + ++K + + I A +D+ Y + +TN GE
Sbjct: 6292 NTEGAK---AKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQANYNVSLTNHRGE 6347
Query: 627 DVASIFLQVVDVPD 640
+V S +V+ D
Sbjct: 6348 NVKSAANLIVEEED 6361
Score = 123 bits (309), Expect = 9e-28
Identities = 99/374 (26%), Positives = 159/374 (42%), Gaps = 25/374 (6%)
Query: 250 VEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGK 309
V+ K+ FT++L ++ E S+P + +KW+K+G E+ KY + K
Sbjct: 2122 VQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRK 2181
Query: 310 KRILTINKCTLADDAAYE-VAVKDE--KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366
L+I +D Y V V+DE K +L V+ V V L+D +V E+
Sbjct: 2182 VHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELE 2241
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
VS E + W + VEL +Y R L DV +ED+G Y + +G
Sbjct: 2242 CIVSPENIEGKWYHNDVELKSN----GKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2297
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
+ +L ++ + + +LQ ++D V + + +VS E V G W K+G EV+PS R+ I
Sbjct: 2298 KTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI 2357
Query: 487 SHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCS 546
+ H L+I+D+ ED G+Y+F LS S +++ + V
Sbjct: 2358 VIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV---------------- 2401
Query: 547 GKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIE 606
T + V+ G K L+ ++ W DE + I K VI
Sbjct: 2402 -ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK-QRLVIN 2459
Query: 607 SAQREDEGRYTIKV 620
DEG Y + V
Sbjct: 2460 RTHASDEGPYKLIV 2473
Score = 121 bits (303), Expect = 4e-27
Identities = 99/330 (30%), Positives = 138/330 (41%), Gaps = 46/330 (13%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR------------------- 593
++ V G+++ LD SI+G P P TW+K + V E + R
Sbjct: 8316 SLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFV 8375
Query: 594 --IEKRVDC-------SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP-- 642
+ +R+ S + + R D G Y IKV N G A + V+D P PP
Sbjct: 8376 LPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN 8435
Query: 643 ---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER--KKKGSQRWMKLNFEVFTETT 697
E +R TSV + WEPP+ DGG + Y +E+ K K W+ +
Sbjct: 8436 FVFEDIRKTSV-----LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCK 8489
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTT 754
Y TK+IEG Y RV A N G P + +KP + P P P IVEDVT +
Sbjct: 8490 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8548
Query: 755 LKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGV 814
+KW P G+ I GY +E S W N + V L G +FRV
Sbjct: 8549 VKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAE 8607
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N AG + + + P T + PP +PR
Sbjct: 8608 NAAGPGKFSPPSDPKTAHDPISPPGPPIPR 8637
Score = 120 bits (302), Expect = 6e-27
Identities = 88/295 (29%), Positives = 136/295 (46%), Gaps = 15/295 (5%)
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
AG ++L I+G+P P W K D+ T +E D +S +I+ A R + G Y
Sbjct: 20514 AGTSVKLRAGISGKPAPTIEWYKDDKELQTN-ALVCVENTTDLASILIKDADRLNSGCYE 20572
Query: 618 IKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
+K+ N +G A+I +Q++D P PP + +V + L+W PP DGG +T Y+VE
Sbjct: 20573 LKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE 20632
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP-----SMNTKPF 731
+++ W ++ E E +TK+I+G Y RV AVN G+ +P + F
Sbjct: 20633 KRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAF 20691
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
+ P P V +T + T+ W P G I GY +E + S W E +
Sbjct: 20692 VTPGPPGIP---EVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 20748
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGR---SEPATLAQPVTIREIAEPP-KIRL 842
V L + +RV VN AG+ SEP+ + + PP KIR+
Sbjct: 20749 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRI 20803
Score = 120 bits (300), Expect = 1e-26
Identities = 87/326 (26%), Positives = 140/326 (42%), Gaps = 29/326 (8%)
Query: 523 LNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGD 582
L+ + K +VP P ++ + +G+ A AG+KLR +T
Sbjct: 23368 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT------------- 23414
Query: 583 EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+E + I D G YT+++ N G +I + ++D P PP
Sbjct: 23415 -----------VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPP 23463
Query: 643 EA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
++I + + WEPP DGG P++GY+VE++ W+ ++ E T +T++ T
Sbjct: 23464 TGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVS-ESVTRSTFKFT 23522
Query: 702 KMIEGILYEMRVFAVNAIGVSQ--PSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
++ EG Y RV A N G+ S + I P L + DV+ TL W P
Sbjct: 23523 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23582
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G + GY+VE ++ WV N PV + L G RV +N G
Sbjct: 23583 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23642
Query: 820 SEPATLAQPVTIRE-IAEPPKIRLPR 844
+P+ ++P+ + IA P K + PR
Sbjct: 23643 GKPSRPSKPIVAMDPIAPPGKPQNPR 23668
Score = 117 bits (294), Expect = 5e-26
Identities = 129/529 (24%), Positives = 197/529 (37%), Gaps = 82/529 (15%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
V +P PP +I G+ + W P++DGG P+TGY VE KK W K + +
Sbjct: 19709 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRG 19767
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLH---------LIVE 746
T Y + + G Y RV +VN +G S PS ++ P + EPL LIV+
Sbjct: 19768 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19827
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+ +R G V L W +T+ R + T
Sbjct: 19828 AGASFTMTVPFR-----------GRPVPNVL-----WSKPDTDLRTRAYVDTTDSRTSLT 19871
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
I A R++ +TI+ + + L + T G N+ V
Sbjct: 19872 I-------ENANRNDSGKYT--LTIQNVLSAASLTLVVKVLDT----PGPPTNITVQDVT 19918
Query: 867 KPRPQVVW----TKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
K + W GGAP+ + R + V LS ++ N+++
Sbjct: 19919 KESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCN------RLSYKVTNLQEG 19972
Query: 923 ATIRIRV--------------------VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
A RV EK PP + V + + + W P+ DG S
Sbjct: 19973 AIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGS 20032
Query: 963 EIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
I+ Y V+ +K W + T VS L +EY+FRV+ EN GLSD
Sbjct: 20033 RIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEYFFRVFAENQAGLSDP----- 20086
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+L + + E E D + P V AG + ++ + G P PKV
Sbjct: 20087 --RELLLPVLIKEQLEPPEIDMKNFPSHTV-----YVRAGSNLKVDIPISGKPLPKVTLS 20139
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALA 1131
++ + ++ +F LT+N++ DAG Y A N G A
Sbjct: 20140 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 20188
Score = 117 bits (293), Expect = 6e-26
Identities = 120/486 (24%), Positives = 203/486 (41%), Gaps = 48/486 (9%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E+S ++ W KNG EI+ S K+ GK L I + D A Y +++
Sbjct: 2858 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSAT 2917
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
L V P++I + L+D D + V V+ EG W+K+GVE+ D K + R K
Sbjct: 2918 LTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTD--KCQMRTK 2973
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
K H L +V D Y + A L VE + +E + I D+ V ++A+F
Sbjct: 2974 K--LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3031
Query: 459 KCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALS 518
+CEVS+ +T +W K+ E++ + RI I H+L+I R D G YT V G +
Sbjct: 3032 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVST 3091
Query: 519 LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW 578
+ ++++ + K+E I + A+V N+ +D A W
Sbjct: 3092 AKLFVEGRDVRIRSI-KKEVQVIE-------KQRAVVEFEVNEDDVD----------AHW 3133
Query: 579 LK-GDEVFTTTEGRTR--IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
K G E+ + R + +E+R+ I ++ D G YT G + +S+ L
Sbjct: 3134 YKDGIEINFQVQERHKYVVERRI--HRMFISETRQSDAGEYTF----VAGRNRSSVTL-Y 3186
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNFEVFT 694
V+ P+PP+ ++ +P GKP ++ + + W K E
Sbjct: 3187 VNAPEPPQVLQ-----------ELQPVTVQSGKPARFCAVISGRPQPKISWYK--EEQLL 3233
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTT 754
T ++ + +G Y + + + + K +A TS L + V +V
Sbjct: 3234 STGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Query: 755 LKWRPP 760
+ PP
Sbjct: 3294 MPVYPP 3299
Score = 117 bits (293), Expect = 6e-26
Identities = 130/526 (24%), Positives = 205/526 (38%), Gaps = 68/526 (12%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF--EVFTET 696
P PEA+ T D L W+PP +DGG + GY+VE +K G + W + N E ET
Sbjct: 10744 PVNPEAIDTTCNSVD---LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 10800
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLK 756
Y+ T + +G Y+ RV AVNA G S P+ +P + + EP LI++ +K
Sbjct: 10801 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIK 10859
Query: 757 WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR------ 810
R+ A +++ W + + + V P G+++ R
Sbjct: 10860 VGDTLRLSA------IIKGVPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHED 10911
Query: 811 --VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF---- 864
+ + + + T++ V + + PP R L + IRK L P
Sbjct: 10912 GGIYSLTVENPAGSKTVSVKVLVLDKPGPP-----RDLEVSEIRKDSCYLTWKEPLDDGG 10966
Query: 865 --------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI 916
+ + W+ A + + + R AA + G +
Sbjct: 10967 SVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPF---V 11023
Query: 917 ENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKT 976
E K + + GPP ++ +V T + W P DG S I GY V+ ++ T
Sbjct: 11024 ETPKPIKALD--PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT 11081
Query: 977 MEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
+W ++ + C V+ L G Y FRV ENI GL G+ T P
Sbjct: 11082 QDWIK-FKTVTNLECVVTGLQQGKTYRFRVKAENIVGL----GLPDTTI----------P 11126
Query: 1037 FEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
E +E + + LI+ +VV AG + +RG P P W + EI+ D +
Sbjct: 11127 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11186
Query: 1096 I--TNYQGVLTLN--IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N+ VLT+ +RR D G Y N G L V
Sbjct: 11187 VETDNFSSVLTIKNCLRR----DTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 117 bits (293), Expect = 6e-26
Identities = 82/297 (27%), Positives = 135/297 (45%), Gaps = 18/297 (6%)
Query: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
+ +++ +G LR+ + G P P TW K D V I + +S + A R+
Sbjct: 21594 DGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGSTSLFVRDATRD 21652
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPV 670
G YT++ N G A I ++V D P +R T++ + L W+ P+ DG P+
Sbjct: 21653 HRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPI 21712
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
T Y++E+++ W + + + +Y + K+I G Y+ RV AVN GV +P +++ P
Sbjct: 21713 THYIIEKRETSRLAWALIEDKCEAQ-SYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDP 21770
Query: 731 F-------MPIAP-TSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+P AP EP ++T + TL W P G I Y++E + S
Sbjct: 21771 VVAQIQYTVPDAPGIPEP-----SNITGNSITLTWARPESDGGSEIQQYILERREKKSTR 21825
Query: 783 WVPA-NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
WV + P+ F V L G F V+ N AG + +++ + RE PP
Sbjct: 21826 WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 21882
Score = 117 bits (292), Expect = 8e-26
Identities = 112/425 (26%), Positives = 166/425 (39%), Gaps = 46/425 (10%)
Query: 729 KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
KP +P P ++VT TLKW PP G I Y++E + +WV
Sbjct: 13703 KPGIPTGPIK------FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC-A 13755
Query: 789 EPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPVTIREIAEPPKIRLP 843
V++ F V L G FRV N G +SEP P + + PP I
Sbjct: 13756 SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDV 13815
Query: 844 RH----LRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFV 899
RH L T +K G + K R ++W + ++ +R DF
Sbjct: 13816 RHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA------NKTPIRMRDF------ 13863
Query: 900 RQAARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
+ ++ EYE V N+ + + ++ PP V + + + W
Sbjct: 13864 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWT 13923
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
PK DG ++ GY V+K D + W N + TV+DL+ G +Y FR+ +N G
Sbjct: 13924 EPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAG 13983
Query: 1014 LSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC-AVR 1072
+P S T I K EY+ + P L + AG + LN ++
Sbjct: 13984 AISAPSESTETI-ICKD-------EYEAPTIVLDPTIKDGL---TIKAGDTIVLNAISIL 14032
Query: 1073 GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAE 1132
G P PK W K +IR IT+ L I+ + DAG YT A N G +
Sbjct: 14033 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 14092
Query: 1133 CKLEV 1137
K+ V
Sbjct: 14093 VKVTV 14097
Score = 115 bits (287), Expect = 3e-25
Identities = 132/509 (25%), Positives = 215/509 (42%), Gaps = 64/509 (12%)
Query: 159 DASGQSLESFKRTSEK---KSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIW 215
+ S + FKR +E+ ++ TA EL +K++ EE +K KD E+
Sbjct: 1946 EESEELRSKFKRRTEEGYYEAITAVELKS----RKKDESYEELLRKTKD--------ELL 1993
Query: 216 ELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLD--PAYQVDRGNK 273
K + E + +A + IT + K K+E+ S K + + V +G+
Sbjct: 1994 HWTKELTEEEKKALAEEGKIT-----IPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSD 2048
Query: 274 IKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVF----ENVGKKRILTINKCTLADDAAYEV 328
V + PD +W+KNG +I+ S + + +NV + L I T D A+ V
Sbjct: 2049 AHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE---LVIRDVTAEDSASIMV 2105
Query: 329 A---VKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAV---EVSEEGAQVMWMKDG 382
+ E + + LI E Q V ++ MA E SE +V W KDG
Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2165
Query: 383 VELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI---TNGGQCEAELIVEEKQL 439
+E+ D +YR D K H L + D Y + + A+LIVE +
Sbjct: 2166 MEVHEGD----KYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVV 2221
Query: 440 EVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
E ++++ D+ V S +C VS E + GKWY N VE++ + + TI+ L + D
Sbjct: 2222 EFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKD 2281
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V ED+G+Y+FV DG + K+ K P I S + V G
Sbjct: 2282 VTKEDQGEYSFVIDGKKTTCKLKM-----------KPRPIAILQGLSDQK------VCEG 2324
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+ ++L+V ++ E W+K G EV + I+K+ +IE +ED G Y+
Sbjct: 2325 DIVQLEVKVSLESVE-GVWMKDGQEVQPSDRVHIVIDKQ--SHMLLIEDMTKEDAGNYSF 2381
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ + + VDV P + V +
Sbjct: 2382 TIPALGLSTSGRVSVYSVDVITPLKDVNV 2410
Score = 114 bits (286), Expect = 4e-25
Identities = 137/562 (24%), Positives = 213/562 (37%), Gaps = 62/562 (11%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE-DVASIFLQVVDV---PDP 641
T T+ R R+ + S+ A G VGE S+F + D P P
Sbjct: 18583 TLTDLRLRVTGLTEGHSYEFRVAAENAAG---------VGEPSEPSVFYRACDALYPPGP 18633
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYES 700
P ++T L W P+YDGG PV GY+VE K+ + W + +
Sbjct: 18634 PSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18693
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTS-EP--------LHLIVEDVTDT 751
TK+ E Y R+ A+N+ GV +P+ T P +A EP L +V
Sbjct: 18694 TKLKENTEYNFRICAINSEGVGEPA--TLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18751
Query: 752 T----TTLKWRPPNRIGAGGIDGYLVEYC-LEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+K RP + +G L + +E + + + V R NL
Sbjct: 18752 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 18811
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ VN+ P+ +TIRE+ K + I + N +V +
Sbjct: 18812 SGSKTAFVNVRVLDSPSAPVN-LTIREVK---KDSVTLSWEPPLIDGGAKITNYIVEKRE 18867
Query: 867 KPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
R T R+ F V S EY + + E T
Sbjct: 18868 TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA-----SNEYGIGLPAET-----TEP 18917
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++V E PP V + +V A ++W+ P+ DG S+I GY V+ K + +W + +
Sbjct: 18918 VKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKW-STCTQV 18976
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP-FEYKEHDFR 1045
+ T+S L G EY FRV N G SD + ++ I KP E H F
Sbjct: 18977 KTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG---VPVIARDIEIKPSVELPFHTFN 19033
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
V A ++ +G P+ V W K+ ++E + +++ + V +L
Sbjct: 19034 -------------VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 19080
Query: 1106 NIRRPSPFDAGTYTCRAVNELG 1127
+I+ S D GTY N G
Sbjct: 19081 SIKEASKEDVGTYELCVSNSAG 19102
Score = 111 bits (277), Expect = 4e-24
Identities = 74/266 (27%), Positives = 120/266 (45%), Gaps = 9/266 (3%)
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFE 305
K ++K A KK V VE++ P++ ++W KNG ++ + KY
Sbjct: 2651 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2710
Query: 306 NVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEM 365
G L I C + D++ Y + L V+ V I+ +D V
Sbjct: 2711 VKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVET--VKIIKKPKDVTALENATVAF 2768
Query: 366 AVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNG 425
V VS + V W VE+ D ++R + K H L+ ++ D G Y +
Sbjct: 2769 EVSVSHDTVPVKWFHKSVEIKPSD----KHRLVSERKVHKLMLQNISPSDAGEYTAVVGQ 2824
Query: 426 GQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRIT 485
+C+A+L VE L + + + ++ V ++ A F+CEVS V W KNGVE+ S++
Sbjct: 2825 LECKAKLFVET--LHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFK 2882
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFV 511
I G+ H+L+I + ED +YTFV
Sbjct: 2883 IVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Score = 108 bits (271), Expect = 2e-23
Identities = 107/416 (25%), Positives = 166/416 (39%), Gaps = 37/416 (8%)
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
+P S L +D+ + + WRPP G I GY++E W ++ V
Sbjct: 23855 SPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGT 23913
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK--IRLPRHLRQT--- 849
VK L FRV N G S+P +PVT + PP+ P L T
Sbjct: 23914 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSS 23973
Query: 850 ----YIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDF-DTVFFVRQA 902
+ R + + V + + K W + T+ ++ T D + R
Sbjct: 23974 VSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRII 24033
Query: 903 ARSDSGEYELSVQIENM--KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDG 960
A++D G E S E + KD +K P + + + + ++W+ P+ DG
Sbjct: 24034 AQNDVGLSETSPASEPVVCKDP-------FDKPSQPGELEILSISKDSVTLQWEKPECDG 24086
Query: 961 NSEIMGYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
EI+GY+V+ W ER + T+ L+ EY FRV+ EN GLS
Sbjct: 24087 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP-- 24144
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKV 1079
+ TA +KT +T AP + D G +A L+C + G P P +
Sbjct: 24145 --RRTAMSIKTKLTSGE----------APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 24192
Query: 1080 VWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
W + E+ + K+ +++ TL + D G YTC A NE+GE KL
Sbjct: 24193 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24248
Score = 107 bits (266), Expect = 8e-23
Identities = 121/519 (23%), Positives = 189/519 (36%), Gaps = 75/519 (14%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF-EVFTETT 697
P PP ++ L W P YDGG P+ GYLVE K+ S W++ N + +T
Sbjct: 13217 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13276
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT----- 752
+E T ++E Y+ RV+AVN IG S PS P P + D+ T
Sbjct: 13277 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13336
Query: 753 ------TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RPP +I W N +R G +K+
Sbjct: 13337 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKSTDFDTF 13378
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ V AG+ TL +E K+ + G +N+ V
Sbjct: 13379 LRCENVNKYDAGKYI-LTLENSCGKKEYTIVVKV----------LDTPGPPVNVTVKEIS 13427
Query: 867 KPRPQVVWTK----GGAPLDTSRVHVRTSDFDTVFFV---------RQAARSDSGEYELS 913
K V W GG+P+ V R ++ + V R A + Y
Sbjct: 13428 KDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFR 13487
Query: 914 VQIEN---MKDTATIR--IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V EN + D R ++ + GP +++ V+ V ++ + W+ P DG S I+GY
Sbjct: 13488 VFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYV 13547
Query: 969 VQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
V ++ +W V ++ + DL G EY FRV EN + G +
Sbjct: 13548 VDFLTEEN-KWQRVM-KSLSLQYSAKDLTEGKEYTFRVSAEN----ENGEGTPSEITVVA 13601
Query: 1029 KTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI 1088
+ + + K P + + + L ++G P P V W K + +
Sbjct: 13602 RDDVVAPDLDLKG----------LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPL 13651
Query: 1089 REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
D + + + TL + DAG YT N G
Sbjct: 13652 ATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 13690
Score = 107 bits (266), Expect = 8e-23
Identities = 108/487 (22%), Positives = 190/487 (39%), Gaps = 42/487 (8%)
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTET-TYESTKMIEGILYEMRVFAVNAIGVSQPS 725
GKP+ + R + M+ N E+ E T + + + A N+ G ++
Sbjct: 20130 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20189
Query: 726 MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVP 785
+N P + P+ ++ D+T+ + TLKW PP G + Y++ + W
Sbjct: 20190 INIVVLDRPGPPTGPV--VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20247
Query: 786 ANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRL 842
+ V R V L TG FR+ N G S+ A VT++ PP
Sbjct: 20248 VSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSAC-VTVKLPYTTPGPPSTPW 20305
Query: 843 PRHLRQTYI-----RKVGEQLNLVVPF--QGKPRPQVVWTKGGA-PLDTSRVHVRTSDFD 894
++ + I V + VV + + K R ++W K + T+ V T
Sbjct: 20306 VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAG 20365
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
++ R A + +G + S E + ++ PP NV + ++ + + WQ
Sbjct: 20366 LIYEFRVYAENAAGVGKPSHPSEP--------VLAIDACEPPRNVRITDISKNSVSLSWQ 20417
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I GY V++ D W N T +S L ++Y FRV+ N G
Sbjct: 20418 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 20477
Query: 1014 LSDSPGVSKNTARILKT---GITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
+P + + + P EY E K+ AG S L
Sbjct: 20478 SISNPSEVVGPITCIDSYGGPVIDLPLEYTE-----VVKYR---------AGTSVKLRAG 20523
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
+ G P P + W K+ E++ + + N + ++ I+ ++G Y + N +G A
Sbjct: 20524 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 20583
Query: 1131 AECKLEV 1137
A ++++
Sbjct: 20584 ATIRVQI 20590
Score = 106 bits (265), Expect = 1e-22
Identities = 114/409 (27%), Positives = 180/409 (44%), Gaps = 52/409 (12%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
EIS+ D+ +W G+ ++PS + G KR LT++K L D A EV + T
Sbjct: 5047 EISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKL--DQAGEVLYQALNAITT 5104
Query: 339 --LFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-VSEEGAQVMWMKDGVELTREDSFKARY 395
L VKE + PL+D V V +R + E V A V+W K + D F
Sbjct: 5105 AILTVKEIELDFAVPLKD--VTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFD--- 5159
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQ 455
DGK+HIL+ +D +D G Y G + A L V +L+ + + D TVK E
Sbjct: 5160 -IIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGET 5218
Query: 456 AVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
A F CE+S EK+ W+KN ++ S+ + IS G+ HKL + +V +D
Sbjct: 5219 ATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQ--IKAQVK 5276
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
LS +A+L LE P + KT+ V +++ L ++ + P
Sbjct: 5277 ELSSTAQLKVLE---------ADPYFTVKLHDKTA------VEKDEITLKCEVSKDVP-- 5319
Query: 576 ATWLK-GDEVFTT------TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 628
W K G+E+ + +G RI K I+ A +D+G Y +
Sbjct: 5320 VKWFKDGEEIVPSPKYSIKADGLRRILK--------IKKADLKDKGEYVCDCGTDKTKAN 5371
Query: 629 ASIFLQVVDVPDPPEAVRITSVGE--DWAILVWEPPMYD----GGKPVT 671
++ +++ V P V + VGE + I + EP ++ G+P+T
Sbjct: 5372 VTVEARLIKVEKPLYGVEV-FVGETAHFEIELSEPDVHGQWKLKGQPLT 5419
Score = 103 bits (256), Expect = 1e-21
Identities = 109/405 (26%), Positives = 177/405 (43%), Gaps = 35/405 (8%)
Query: 249 KVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVG 308
KV+V + AA ++ G K + + IS ++W ++ + ++ KY G
Sbjct: 6172 KVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADG 6231
Query: 309 KKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE 368
KKR+L + TL D Y V V + L V E + IV PL+D +V V E
Sbjct: 6232 KKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCE 6290
Query: 369 VSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV-ITN--- 424
V+ EGA+ W ++ E DS ++Y + + L D +D+ Y V +TN
Sbjct: 6291 VNTEGAKAKWFRN--EEAIFDS--SKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6346
Query: 425 -GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKR 483
+ A LIVEE+ L +++ + D+ + F C+V+ VT KW KNG EV R
Sbjct: 6347 ENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNR 6406
Query: 484 ITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHL 543
++ H L I D DEG+Y V G S+ A+L +E E+V HL
Sbjct: 6407 VSYRVDKYKHMLTIKDCGFPDEGEY-IVTAGQDKSV-AELLIIEAPTEFVE-------HL 6457
Query: 544 DCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT-RIEKRVDCSS 602
+ T + V ++ E V + G E+ EG+ + EK
Sbjct: 6458 EDQTVTEFDDAV--------FSCQLSREKANVKWYRNGREI---KEGKKYKFEKDGSIHR 6506
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQ--VVDVPDPPEAV 645
+I+ + +DE Y V + + A +F++ V++ PP+ +
Sbjct: 6507 LIIKDCRLDDECEYACGVED--RKSRARLFVEEIPVEIIRPPQDI 6549
Score = 102 bits (254), Expect = 2e-21
Identities = 114/516 (22%), Positives = 191/516 (37%), Gaps = 76/516 (14%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP +RI + L W P+YDGG VTGY+VE ++ + W ++ +
Sbjct: 20792 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20851
Query: 696 TT-YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMP-------------------IA 735
TT Y + + G+ Y RV AVN G +P +P IA
Sbjct: 20852 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIA 20911
Query: 736 PTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERC 794
E + +++ T+ WR + G Y +E S +P T +
Sbjct: 20912 KAGEDVQVLIPFKGRPPPTVTWRKDEK-NLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20970
Query: 795 GFTVKN---LPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
T++N P + + +V+ A + T+ + +PP I + I
Sbjct: 20971 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
K + + W+ ++ + T FF R A ++ G E
Sbjct: 21031 EK-------------RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 21077
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
E +K E P ++ +K+ T+ ++ W P DG S I Y V++
Sbjct: 21078 PCETTEPVK--------AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 21129
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
K W + ++ VS L + FRV+ +N GLSD
Sbjct: 21130 KGKGEQTWSHA-GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------- 21174
Query: 1032 ITFKPFEYKEHDFRMAPKFLTPLIDR--------VVVAGYSAALNCAVRGHPKPKVVWMK 1083
+T P KE +TP +D V G++ L +G PKP + W+K
Sbjct: 21175 VTIGPITVKE-------LIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLK 21227
Query: 1084 NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1119
+ + ++E + + +TL+I+ G YT
Sbjct: 21228 DGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21263
Score = 99.8 bits (247), Expect = 1e-20
Identities = 71/264 (26%), Positives = 127/264 (48%), Gaps = 11/264 (4%)
Query: 268 VDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K L ++S PD+T +KW+ N ++IKP + G K+ L IN+ +D+ Y
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2469
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMW-MKDGVEL 385
++ V + L V++ + I+ L D V VE+S G V+W KD
Sbjct: 2470 KLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKD---- 2523
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+E ++Y+ + GK + L +++++D G+Y +L V + + +
Sbjct: 2524 -KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPL 2580
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
D TV S++AVF+CEV++ G+W ++G + + I G +L+I + +D
Sbjct: 2581 TDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDI 2640
Query: 506 GDYTFVPDGYALSLSAKLNFLEIK 529
G+YT+ S K+ ++IK
Sbjct: 2641 GEYTYKVATSKTSAKLKVEAVKIK 2664
Score = 99.0 bits (245), Expect = 2e-20
Identities = 109/513 (21%), Positives = 188/513 (36%), Gaps = 49/513 (9%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV-FTETT 697
P PP ++ + L W P+YDGG + GY+VE+ W +T
Sbjct: 16466 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 16525
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP---LHLIVEDVTDTTT- 753
E K++E Y R+ A+N GV + + P + P L L + + +
Sbjct: 16526 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 16585
Query: 754 -------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RP + G +DG + + + + + V +G
Sbjct: 16586 GSLRLFVPIKGRPTPEVKWGKVDGEIRDAAI------IDVTSSFTSLVLDNVNRYDSGKY 16639
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF-Q 865
L + T + VT+R + P P +L+ T I K + P
Sbjct: 16640 TLTL--------ENSSGTKSAFVTVRVLDTPSP---PVNLKVTEITKDSVSITWEPPLLD 16688
Query: 866 GKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE---NMKDT 922
G + + + S V T+ + + Q S + ++ + E +
Sbjct: 16689 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16748
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I+V E PP + V +V + + W P+ DG S+I+ Y V+ K + +W
Sbjct: 16749 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16808
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
R + +++L G EY FRV N G SD R L I K
Sbjct: 16809 -ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP--------RSLAVPIVAK------- 16852
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P V G + + G PKP + W K+ + +++ + +T+ +
Sbjct: 16853 DLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDL 16912
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
TL+I+ D G Y N +G+ A ++
Sbjct: 16913 TTLSIKETHKDDGGQYGITVANVVGQKTASIEI 16945
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/541 (23%), Positives = 199/541 (36%), Gaps = 74/541 (13%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP + + L W+PP DGG P+ GY+VE +++G+ W ++N TT
Sbjct: 9333 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9392
Query: 699 EST--KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT--- 753
E + E Y RV AVN G S+PS T EP I D
Sbjct: 9393 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9452
Query: 754 --------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGA 805
+K RP + + DG + +G + +P + + +V +P
Sbjct: 9453 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 9510
Query: 806 RILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-- 863
R + ++ T V + ++ PPK L+ + I + +L+ +P
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 9565
Query: 864 ----------FQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + WTK ++ V + +F R A + G +
Sbjct: 9566 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG---IG 9622
Query: 914 VQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--- 970
+E ++ T T R + PPI + + + + W+ PK+DG S + Y V+
Sbjct: 9623 PPVETIQRT-TARDPIYPP-DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 9680
Query: 971 --KADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
K W +R+ TV DL+ G EY FRV N G+S
Sbjct: 9681 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVS------------ 9728
Query: 1028 LKTGITFKPFEYKEHDFRMAPKFLTPLID----RVVVAGYSAALNCAVRGHPKPKVVWMK 1083
K T P + + D + P ID V G + + ++G P P + W K
Sbjct: 9729 -KPSATVGPCDCQRPD-------MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9780
Query: 1084 -------NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
NK + D TL I + D G YT AVN LG A E +L
Sbjct: 9781 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9840
Query: 1137 V 1137
V
Sbjct: 9841 V 9841
Score = 97.4 bits (241), Expect = 7e-20
Identities = 101/436 (23%), Positives = 166/436 (38%), Gaps = 41/436 (9%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N+ G + ++N P + P+ + ++VT + TL W PP G I+ Y+VE
Sbjct: 15852 NSAGEAIETLNVIVLDKPGPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKR 15909
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS-----EPATLAQPVTI 831
+ W + V R L TG FR+ N G+S EP P +
Sbjct: 15910 DTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 15968
Query: 832 REIAEPPKIRLPRH--LRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVH 887
P + L + + + + + V+ + + K R ++W K ++
Sbjct: 15969 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVK------LNKTP 16022
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENM----KDTATIRIRVV-EKAGPPINVMVK 942
+ + F T + EYE V EN+ K + V + PP
Sbjct: 16023 IPQTKFKTT------GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAI 16076
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR-HTSCTVSDLIVGNE 1001
V + ++W+ P DG S+I GY V+K + W N T V+ L+ +
Sbjct: 16077 IVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHR 16136
Query: 1002 YYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVA 1061
Y FRV N G+ P S TG E M PK+ + VV A
Sbjct: 16137 YEFRVIARNAAGVFSEPSES--------TGAITARDEVDPPRISMDPKYKDTI---VVHA 16185
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
G S ++ + G P P + W+K E+ + I + +L+++ D+G Y +
Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16245
Query: 1122 AVNELGEALAECKLEV 1137
A N GE ++V
Sbjct: 16246 AKNVAGERSVTVNVKV 16261
Score = 95.5 bits (236), Expect = 3e-19
Identities = 116/453 (25%), Positives = 166/453 (36%), Gaps = 51/453 (11%)
Query: 694 TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT 753
T + + T +G Y + V N +G S+ P P+ +DV+ +
Sbjct: 16913 TTLSIKETHKDDGGQYGITV--ANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESI 16968
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813
TL W PP G I Y+V+ + W + V R V L TG FR+
Sbjct: 16969 TLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFA 17027
Query: 814 VNIAGRS---EPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLN------LVVPF 864
N G+S E + +E P + + + + E +N +
Sbjct: 17028 ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 17087
Query: 865 QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM---- 919
+ K R ++WTK ++ + +H DT F +A + G EYE V EN+
Sbjct: 17088 ERKERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVG 17134
Query: 920 ----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ + G P +MVK ++W P DG S I GY V+K D
Sbjct: 17135 KASKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLP 17191
Query: 976 TMEWFNVYERNR-HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF 1034
W N T TVS L Y FRV +N G P S TG
Sbjct: 17192 DGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDS--------TGPIT 17243
Query: 1035 KPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF 1094
E + M PKF + VV AG + L V G P P + W++ EI E +
Sbjct: 17244 AKDEVELPRISMDPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARC 17300
Query: 1095 LITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
I N L ++ D G Y RA N G
Sbjct: 17301 EIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 17333
Score = 94.4 bits (233), Expect = 6e-19
Identities = 72/213 (33%), Positives = 98/213 (46%), Gaps = 16/213 (7%)
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHT 989
EK G P + V + +V W+ P DG ++I Y+++K +KK +W +V E R T
Sbjct: 24451 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24510
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK 1049
+V +LI G EY FRV EN+ G S+ +S +P K AP
Sbjct: 24511 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-------------EPITPKSDVPIQAPH 24557
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP-KFLITNYQ-GVLTLNI 1107
F L + V +A L C V GHPKP V W + EI D K+ I ++ G L I
Sbjct: 24558 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 24617
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
+ DA Y RA N+ G LEV VP
Sbjct: 24618 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24650
Score = 94.0 bits (232), Expect = 7e-19
Identities = 95/391 (24%), Positives = 171/391 (43%), Gaps = 37/391 (9%)
Query: 240 GMLKRLKKAKVEVKK-SAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQ-EIK 297
G ++ AK+ V++ F K L+ V +G + L E++ + + W K+G+ ++
Sbjct: 4823 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVE 4881
Query: 298 PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFT-ELFVKEPPVL---IVTPLE 353
+ V +G R LTIN D Y V V++ VK V+ +V P+
Sbjct: 4882 KPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIR 4941
Query: 354 DQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQ 413
DQ V A +++++ + W K E+ E + K +DG L + +
Sbjct: 4942 DQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTE--ILRDGNHLYLKIKNAMP 4999
Query: 414 EDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYK 473
ED Y V G + A+L + E+++E+L+ I D+T+ E A F E+S+ + G+W
Sbjct: 5000 EDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKL 5059
Query: 474 NGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEY- 532
G +RPS I G L + V+ + G+ + +A L EI++++
Sbjct: 5060 KGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLY--QALNAITTAILTVKEIELDFA 5117
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
VP ++ + V + R + +T E + W KG ++ +++
Sbjct: 5118 VPLKD----------------VTVPERRQARFECVLTREANVI--WSKGPDIIKSSDKFD 5159
Query: 593 RI---EKRVDCSSFVIESAQREDEGRYTIKV 620
I +K + VI +Q +DEG YT +V
Sbjct: 5160 IIADGKKHI----LVINDSQFDDEGVYTAEV 5186
Score = 92.8 bits (229), Expect = 2e-18
Identities = 113/454 (24%), Positives = 174/454 (38%), Gaps = 76/454 (16%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
NA G S+ K P + L V VT TL W P G I Y+VE
Sbjct: 22752 NASGTKAVSVMVKVLDSPGPCGK---LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERR 22808
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE--- 833
WV E + V L +FRV VN G P ++P+ R
Sbjct: 22809 ETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFT 22866
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVR 889
I PP I +VG GK + WTK GG + V R
Sbjct: 22867 IPSPPGIP----------EEVGT---------GKEHIIIQWTKPESDGGNEISNYLVDKR 22907
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE------------------ 931
++ + R D Y+ +++ ++ + + RV
Sbjct: 22908 EKK--SLRWTR--VNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISC 22963
Query: 932 -----KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
GPP V + + + W P DG ++I+GY ++ +K T +W+ V+
Sbjct: 22964 REPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNA 23023
Query: 987 --RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKE-HD 1043
R+T TV DL +G +Y FRV N+ G+S+ S++ A I +P E E D
Sbjct: 23024 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSE---YSESIAEI-------EPVERIEIPD 23073
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+A + R AG S L +V G P P + W K +++ + +I +
Sbjct: 23074 LELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITWSKQGIDLAS--RAIIDTTESYS 23128
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L + + + +DAG YT A N+ G+ A ++V
Sbjct: 23129 LLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23162
Score = 91.7 bits (226), Expect = 4e-18
Identities = 62/245 (25%), Positives = 116/245 (47%), Gaps = 7/245 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G+ ++L V++S + W K+GQE++PS + + +L I T D Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVEL 385
+ T V V ++TPL+D V G + + +VS + V W + ++
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+D +A + G + L+ + D G Y++I + L VE+ +++++ +
Sbjct: 2440 KPDDRVQAIVK----GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEK--IKIIRGL 2493
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
DLT ++ VF+ E+S + W E++PS + I G+ +KL + ++ +DE
Sbjct: 2494 RDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDE 2553
Query: 506 GDYTF 510
G YTF
Sbjct: 2554 GKYTF 2558
Score = 91.3 bits (225), Expect = 5e-18
Identities = 106/430 (24%), Positives = 163/430 (37%), Gaps = 59/430 (13%)
Query: 734 IAPTSEPLHLI-VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
+ P S+P I +++ + L W P G G I Y +E W + V
Sbjct: 21282 LGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VA 21340
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
R F V NL A FRV N G ++QP+ I + R+P + I
Sbjct: 21341 RTTFKVPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPGPPGKPVIY 21394
Query: 853 KV---GEQLNLVVPF------------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
V G L P + K R ++W K ++TS + R
Sbjct: 21395 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK----VNTSPISGRE------- 21443
Query: 898 FVRQAARSDSGEYELSVQIENMKDTA--------TIRIRVVEKAGPPINVMVKEVWGTNA 949
R + +Y+ V EN + T+ + V+ G P + +V
Sbjct: 21444 -YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETI 21499
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYT 1008
++W P DG S+I+GY ++K W + TV+ L G+ Y FR+
Sbjct: 21500 TLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21558
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALN 1068
N G P S +GI E P++ LI + +G S +
Sbjct: 21559 RNAVGTISPPSQS--------SGIIMTRDENVPPIVEFGPEYFDGLI---IKSGESLRIK 21607
Query: 1069 CAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
V+G P P+V W K+ +EI + IT+ G +L +R + G YT A N G
Sbjct: 21608 ALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGS 21667
Query: 1129 ALAECKLEVR 1138
A AE K++V+
Sbjct: 21668 AKAEIKVKVQ 21677
Score = 90.1 bits (222), Expect = 1e-17
Identities = 92/433 (21%), Positives = 171/433 (39%), Gaps = 41/433 (9%)
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
AK+ V+ + + QV + + E+++ D+ W+K+G EI + + V
Sbjct: 3092 AKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYV 3151
Query: 308 GKKRI--LTINKCTLADDAAYEVAVKDEKCFTELFVKEP-PVLIVTPLEDQQVFVGDRVE 364
++RI + I++ +D Y + L+V P P ++ L+ V G
Sbjct: 3152 VERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPAR 3211
Query: 365 MAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQED-------- 415
+S ++ W K+ E FK + F DG+ + L+ + ED
Sbjct: 3212 FCAVISGRPQPKISWYKE--EQLLSTGFKCK--FLHDGQEYTLLLIEAFPEDAAVYTCEA 3267
Query: 416 RGRYQVITNGGQCEAEL---IVEEKQLEV-----LQDIADLTVKASEQAVFKCEVSDEKV 467
+ Y V T E+ + ++++ V + + D + A F+C VS +
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3327
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNF-L 526
WY +++PS+ ++ ++L I + PEDEG YTFV +S+ N L
Sbjct: 3328 KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Query: 527 EIKVEYVPKQEPPKIHLDCSGKTSE-------------NAIVVVAGNKLRLDVSITGEPP 573
E ++ + H+ S + +++ V G +R ++G P
Sbjct: 3388 EGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPK 3447
Query: 574 PVATWLKGDEVFTTTEGRT-RIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF 632
P W ++ T+ E+ + +I A E G+Y+ K N GE +
Sbjct: 3448 PEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAAT 3507
Query: 633 LQVVDVPDPPEAV 645
L V P PE++
Sbjct: 3508 LTV--TPKAPESI 3518
Score = 90.1 bits (222), Expect = 1e-17
Identities = 105/434 (24%), Positives = 163/434 (37%), Gaps = 37/434 (8%)
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
E ++ NA G +++ P + P++++ DVT T+ W+PP G +
Sbjct: 11208 EYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVI 11265
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
Y+VE + W ++ + + +L G +FRV N G P V
Sbjct: 11266 NYIVEKQDTRKDTWGVVSSGS-SKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV 11324
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
+ + P P T I + ++ +P P + + V V
Sbjct: 11325 AKHKFSPPSP---PGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11381
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPINVMV 941
+ + F R + YE V EN+ + R ++ GPPIN +
Sbjct: 11382 KTPIADLKF-RVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKL 11440
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEW--FNVYERNRHTSCTVSDLIVG 999
K+ A + W P DG S I+GY V+ T +W N E R + V LI G
Sbjct: 11441 KDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 11500
Query: 1000 NEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVV 1059
NEY FR+ NI G + R L + K D P+ + R V
Sbjct: 11501 NEYRFRIKAANIVG--------EGEPRELAESVIAK-------DILHPPEVELDVTCRDV 11545
Query: 1060 VA---GYSAALNCAVRGHPKPKVVWMK-NKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ G + + V+G P+P + W K K+ +RE LI + V L I+ D
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADH 11604
Query: 1116 GTYTCRAVNELGEA 1129
G Y A N G A
Sbjct: 11605 GKYIISAKNSSGHA 11618
Score = 89.4 bits (220), Expect = 2e-17
Identities = 103/435 (23%), Positives = 167/435 (38%), Gaps = 40/435 (9%)
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
YE+++ NA+G + ++ + P P+ + VT TL WRPP G I
Sbjct: 20571 YELKLR--NAMGSASATIRVQILDKPGPPGGPIEF--KTVTAEKITLLWRPPADDGGAKI 20626
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE W + E +E C T + G +FRV VN G EP
Sbjct: 20627 THYIVEKRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSV 20685
Query: 829 VTIREIAEPPKIRLPRHLRQT-------YIRKVGEQLNLVVPF--QGKPRPQVVWTKG-G 878
V P +P + T + R + + + + + + + + + W K
Sbjct: 20686 VAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLK 20745
Query: 879 APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN 938
+ +R V ++ + R A + +G+ S E K I + GPP
Sbjct: 20746 ETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI-----DPPGPPAK 20800
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSDL 996
+ + + ++ + W P DG S + GY V+ + EW V + R T VS+L
Sbjct: 20801 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 20860
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G YYFRV N G + +++ P + K D AP+ +
Sbjct: 20861 KPGVNYYFRVSAVNCAGQGEPIEMNE-------------PVQAK--DILEAPEIDLDVAL 20905
Query: 1057 RVVV---AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPF 1113
R V AG + +G P P V W K++ + D ++ I N L I + +
Sbjct: 20906 RTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN 20965
Query: 1114 DAGTYTCRAVNELGE 1128
D G Y N +GE
Sbjct: 20966 DTGKYILTIENGVGE 20980
Score = 89.4 bits (220), Expect = 2e-17
Identities = 134/655 (20%), Positives = 251/655 (38%), Gaps = 101/655 (15%)
Query: 23 KEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPD 82
K++ K + ++ P+ P + +P V + +V + A K G+
Sbjct: 26453 KKSDQKTTESTVTRKTEPKAPEPISSKP--VIVTGLQDTTVSSDSVAKFAVKATGEP--- 26507
Query: 83 KPTIKWFK-GKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAK 141
+PT W K GK + G K +K S D+G + LE+
Sbjct: 26508 RPTAIWTKDGKAITQGGK------YKLSE-------------------DKGGFFLEIHKT 26542
Query: 142 DTCDSCGFNIDVEAPRQDASGQ---SLESFKRTSEKKSDTAGELDFSGLLKKREVVEEE- 197
DT DS + V+ S ++++ K T +K T + + +K+ VV+EE
Sbjct: 26543 DTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITP--QKKAVVQEEI 26600
Query: 198 ----------KKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKK 247
K + K + L + E ++L + + + + I + + + +
Sbjct: 26601 SQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSI--VHEEITKTSQ 26658
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
A EV+ A K ++ G ++ L I+ +KW NG E+ S +Y +
Sbjct: 26659 ASEEVRTHAEI-KAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNSEEYRYGVS 26716
Query: 308 GKKRILTINKCTLADDAAYEVAVKDE----KCFTELF----VKEPPVLIVTPLEDQQVFV 359
G + LTI + + D+ K + KC +L + + P I P Q +
Sbjct: 26717 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RSQNINE 26775
Query: 360 GDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGR 418
G V E+S E ++ W K+ + + S + + + L + D G+
Sbjct: 26776 GQNVLFTCEISGEPSPEIEWFKNNLPI----SISSNVSISRSRNVYSLEIRNASVSDSGK 26831
Query: 419 YQVITNG--GQCEAEL------IVEEKQLE-VLQDIADLTVKAS------EQAVFKCEVS 463
Y + GQC A +VEE E VL+ D +++ S + + K E S
Sbjct: 26832 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26891
Query: 464 DEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG--DYTFVPDGYALSLSA 521
+ + E++ + ++ + + ++ G + T + + L A
Sbjct: 26892 FSSFSSSSASSMTEMKFAS-MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKA 26950
Query: 522 KLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW-LK 580
+ + K+E +P I + G L + + TGEP P TW
Sbjct: 26951 GIRGIPPKIEALPSD-----------------ISIDEGKVLTVACAFTGEPTPEVTWSCG 26993
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
G ++ + +GR IE D ++ +I Q++D G YT+ + N G D A++ + +
Sbjct: 26994 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 88.2 bits (217), Expect = 4e-17
Identities = 106/434 (24%), Positives = 168/434 (38%), Gaps = 44/434 (10%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ AVN +G + M P P+ E V+ TL W PP G I Y+
Sbjct: 9824 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKF--ESVSADQMTLSWFPPKDDGGSKITNYV 9881
Query: 773 VEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR 832
+E + WV ++EP E C +T+ L G +FR++ N G EP ++P T R
Sbjct: 9882 IEKREANRKTWVHVSSEPKE-CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD-SEPETAR 9939
Query: 833 EIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-FQGKPRPQVVWTKGGAPLDTSRVHVRTS 891
+ P P + + + +N P + G W + DT+ +
Sbjct: 9940 NLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLE---MKDTTSKRWKRV 9994
Query: 892 DFDTVFFV------RQAARSDSGEYELSVQIENM---------KDTATIRIRVVEKAGPP 936
+ D + + + + +Y+ V N D AT R + GPP
Sbjct: 9995 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP-GPP 10053
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSD 995
V + ++A +EW P DG S++ GY V+ ++ EW ++ R T V+
Sbjct: 10054 FP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTG 10112
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G Y FRV NI G+ + PG + E K+ + +
Sbjct: 10113 LKEGAFYKFRVRAVNIAGIGE-PGEVTDV------------IEMKDRLVSPDLQLDASVR 10159
Query: 1056 DRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
DR+VV AG + V G P P V W N+ + ++ T ++ I+
Sbjct: 10160 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSH 10217
Query: 1115 AGTYTCRAVNELGE 1128
G Y+ A NE GE
Sbjct: 10218 QGVYSLLAKNEAGE 10231
Score = 88.2 bits (217), Expect = 4e-17
Identities = 118/461 (25%), Positives = 169/461 (36%), Gaps = 66/461 (14%)
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRI 763
I+G Y +R A N G +N K P P+ V VT +L W PP +
Sbjct: 17319 IDGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQ--VTGVTSEKCSLTWSPPLQD 17374
Query: 764 GAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPA 823
G I Y+VE W +E V V L G +FR++ VN G EP
Sbjct: 17375 GGSDISHYVVEKRETSRLAWTVVASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPL 17433
Query: 824 TLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG--------------EQLNLVVPFQGKPR 869
A + P P+ L T I K E + +V + + R
Sbjct: 17434 ESAPVLMKNPFVLPGP---PKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV--EKRDR 17488
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT-----AT 924
+ W K + R+ T +R ++ EYE V EN AT
Sbjct: 17489 SGIRWIK----CNKRRI--------TDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17536
Query: 925 IRIRVVE---KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEW 979
+ + + K GPP N + + + + W P DG SEI+GY V+ KAD++ +
Sbjct: 17537 VYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQI 17596
Query: 980 FNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEY 1039
R T +S L EY RV N GL ++ V P
Sbjct: 17597 VTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV---------------PGTV 17641
Query: 1040 KEHDFRMAPKFLTPLIDR---VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLI 1096
K D AP+ R VV AG SA ++ +G P P++ W + + E + K I
Sbjct: 17642 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQI 17699
Query: 1097 TNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+I DAG Y + N G A ++V
Sbjct: 17700 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17740
Score = 87.4 bits (215), Expect = 7e-17
Identities = 103/433 (23%), Positives = 161/433 (37%), Gaps = 50/433 (11%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++N K P P+ ++ VT TL W+PP + G I Y+VE
Sbjct: 16246 AKNVAGERSVTVNVKVLDRPGPPEGPV--VISGVTAEKCTLAWKPPLQDGGSDIINYIVE 16303
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPV 829
W + V+ V L G FR++ VN G SEP P
Sbjct: 16304 RRETSRLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPF 16362
Query: 830 TIREIAEPPKIRLPRHLRQTYI----RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR 885
+ + + P++ + G L + + + + WT R
Sbjct: 16363 VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT---------R 16413
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPI 937
H R +R ++ +YE V EN + + K GPP
Sbjct: 16414 CHKRLIG---ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN 16470
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSD 995
N V ++ ++ + W P DG EI GY V+K D EW T+ V
Sbjct: 16471 NPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEK 16530
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L+ +EY FR+ N G+ + V I + E + D + L +I
Sbjct: 16531 LLEKHEYNFRICAINKAGVGEHADVPGPI-------IVEEKLEAPDIDLDLE---LRKII 16580
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRPSPFD 1114
+ + AG S L ++G P P+V W K EIR+ +T ++ ++ N+ R +D
Sbjct: 16581 N--IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNR---YD 16635
Query: 1115 AGTYTCRAVNELG 1127
+G YT N G
Sbjct: 16636 SGKYTLTLENSSG 16648
Score = 87.4 bits (215), Expect = 7e-17
Identities = 98/404 (24%), Positives = 147/404 (36%), Gaps = 63/404 (15%)
Query: 713 VFAVNAIGVSQPSMNT----KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
V A N+ G + +++ KP P+ P ++V+ + W PP G I
Sbjct: 18012 VTATNSAGTATENLSVIVLEKPGPPVGPVR------FDEVSADFVVISWEPPAYTGGCQI 18065
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE + W + V R + L TG FR+ N G+S P
Sbjct: 18066 SNYIVEKRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV 18124
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV---------------VPFQGKPRPQVV 873
+ EP P ++ + + LV + K + ++
Sbjct: 18125 IVQYPFKEPGPPGTP------FVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18178
Query: 874 WTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM----KDTATIRIR 928
W K ++ ++ + F T D G EYE V EN+ K +
Sbjct: 18179 WVK------LNKTPIQDTKFKTTGL-------DEGLEYEFKVSAENIVGIGKPSKVSECF 18225
Query: 929 VV-EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN- 986
V + PP + N ++W+ P DG S+I GY V+K D W N
Sbjct: 18226 VARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18285
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
T TVS L+ Y FRV N G P S IT + E + +
Sbjct: 18286 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGA-------ITARD-EIDAPNASL 18337
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRE 1090
PK+ + VV AG + L +RG P P VVW K+ E+ E
Sbjct: 18338 DPKYKDVI---VVHAGETFVLEADIRGKPIPDVVWSKDGKELEE 18378
Score = 86.7 bits (213), Expect = 1e-16
Identities = 91/398 (22%), Positives = 151/398 (37%), Gaps = 28/398 (7%)
Query: 633 LQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV 692
L +D P P + IT L W P Y GG +T Y+VE++ + RW+K NF
Sbjct: 14982 LDPIDPPGKPVPLNIT---RHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSN 15038
Query: 693 FTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT 752
E + + + E YE RV A NA G P + E + V+ T
Sbjct: 15039 ILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDT 15098
Query: 753 TTLKWRPPNRIGA--GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
LK R+ A G +E+ +G E A E ++ F+ + + R
Sbjct: 15099 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE-IKIADFSTNLVNKDS--TRR 15155
Query: 811 VVGVNIAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKV-----------GEQL 858
G + P A+ + ++ + P P + + K G ++
Sbjct: 15156 DSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15215
Query: 859 NLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN 918
+ + Q + ++ WT + + +++ V + R A + G E
Sbjct: 15216 DHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG------EP 15268
Query: 919 MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTME 978
++ + + PP N V + + +V W P DG SEI+ Y V++ DK
Sbjct: 15269 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 15328
Query: 979 WFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
W ++ VS L G+EY FR+ EN G+S
Sbjct: 15329 WIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 15366
Score = 86.7 bits (213), Expect = 1e-16
Identities = 227/1140 (19%), Positives = 382/1140 (33%), Gaps = 202/1140 (17%)
Query: 83 KPT--IKWF-KGKWLELGSK------SGA-RFSFKESHNSASNVYTVELHIGKVVLGDRG 132
KPT +KW+ G L+ SK SG + H S Y K D
Sbjct: 26028 KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASD-- 26085
Query: 133 YYRLEVKAKDTCDSCGFNIDVEAPRQ------DASGQSLESFKRTSEKKSDTAGELDFSG 186
Y L+V D D E PR ++ SFK+TSE ++ ++ S
Sbjct: 26086 YATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQ 26145
Query: 187 LLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLK 246
+ + RE + + + + + E +KS KI T +L + +
Sbjct: 26146 MTETRESLSSYEHSASAEMKSAALEEKSLE-----EKSTTRKIK----TTLAARILTKPR 26196
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFEN 306
V +SA F+ D +P T+ W + GQ + S+++
Sbjct: 26197 SMTVYEGESARFSCDTD-----------------GEPVPTVTWLRKGQVLSTSARHQVTT 26239
Query: 307 VGKKRILTINKCTLADDAAYEVAV-----KDEKCFTELFVKEPPVLIVTPLEDQQVFVGD 361
K I+ +D+ Y V V K E FT K + ++ V
Sbjct: 26240 TKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK-------ARVTEKAVTSPP 26292
Query: 362 RVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
RV+ + ++ K+ R K H S + +V
Sbjct: 26293 RVKSPEP---------------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKV 26337
Query: 422 ITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPS 481
+ I + + E ++IA LT + EV+ WYK+G +++ +
Sbjct: 26338 QHLPVSAPPK-ITQFLKAEASKEIAKLTCVVESSVLRAKEVT-------WYKDGKKLKEN 26389
Query: 482 KRITISH-VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE----------IKV 530
+ ++L I+++ D+G+Y G + L F+ K+
Sbjct: 26390 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 26449
Query: 531 EYVPKQEPPKIHLDCSGKTSENAI-------VVVAG---------NKLRLDVSITGEPPP 574
K + + KT A V+V G + + V TGEP P
Sbjct: 26450 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 26509
Query: 575 VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
A W K + T G+ ++ + I D G YT V N G +S L
Sbjct: 26510 TAIWTKDGKAITQG-GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLT 26568
Query: 635 VVDVPDPPEAVRITS------VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKL 688
+ + D EA ++++ + A++ E K + ++ + SQ + L
Sbjct: 26569 IKAIKDT-EAQKVSTQKTSEITPQKKAVVQEEISQ----KALRSEEIKMSEAKSQEKLAL 26623
Query: 689 NFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
E E K E + SQ S K F +E
Sbjct: 26624 KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQR 26683
Query: 743 LIVEDVTDTTTTLKW---------RPPNRIGAGGIDGYLV----EYCLEGSEEWVPANTE 789
L+++ T +KW R G G D L + EG + E
Sbjct: 26684 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26743
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
+ +C + + T ++ L PA ++QP R
Sbjct: 26744 GIVKCQYDL----TLSKEL----------SDAPAFISQP------------------RSQ 26771
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSG 908
I + G+ + G+P P++ W K P+ +S V + S +R A+ SDSG
Sbjct: 26772 NINE-GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 26830
Query: 909 EYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
+Y + + + +AT + V+ P +V G +L
Sbjct: 26831 KYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL----------QGSFSSQS 26880
Query: 969 VQKADKKTMEWFNVYERNRHTSCT--------VSDLIVGNEYYFRVYTENICGLSDSPGV 1020
VQ + K F+ + + +S T + E + + + + G+S+ +
Sbjct: 26881 VQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQL 26940
Query: 1021 SKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVV 1080
+T+++LK GI P PK D + G + CA G P P+V
Sbjct: 26941 ESSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 26989
Query: 1081 WM--KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
W K+ +E +F I N + TL I D G YT NE G A + +R
Sbjct: 26990 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 27049
Score = 84.7 bits (208), Expect = 4e-16
Identities = 109/433 (25%), Positives = 158/433 (36%), Gaps = 52/433 (12%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G ++N K P + PL + +T +L W P G ID Y+VE
Sbjct: 19494 NVAGTRSVAVNCKVLDKPGPPAGPLE--INGLTAEKCSLSWGRPQEDGGADIDYYIVEKR 19551
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
W E ++ V L G +FRV GVN G EP + V I+ +
Sbjct: 19552 ETSHLAWTICEGE-LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKALDP 19607
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---- 892
P L T + K E + L RP+ + GG+ + + R +
Sbjct: 19608 FTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERREKNSLRW 19657
Query: 893 --------FDTVFFVRQAARSDSGEYELSVQIEN-----MKDTATIRIRVVEKA---GPP 936
+D V+ + EYE V EN + + IR + PP
Sbjct: 19658 VRVNKKPVYD--LRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPP 19715
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ + T + W P DG + I GY V+ +W + R T T+S L
Sbjct: 19716 SKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 19775
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G EY FRV + N G SD S +I K +E F + + LI
Sbjct: 19776 TTGAEYVFRVKSVNKVGASDPSDSSD--PQIAKE-------REEEPLFDIDSEMRKTLI- 19825
Query: 1057 RVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAG 1116
V AG S + RG P P V+W K ++R + + +L I + D+G
Sbjct: 19826 --VKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIENANRNDSG 19881
Query: 1117 TYTCRAVNELGEA 1129
YT N L A
Sbjct: 19882 KYTLTIQNVLSAA 19894
Score = 84.3 bits (207), Expect = 6e-16
Identities = 200/926 (21%), Positives = 340/926 (36%), Gaps = 134/926 (14%)
Query: 286 TLKWFK-NGQEIKPSSKYVFENV--GKKRILTINKCTLADDAAYEVAVKDEKCFTELFV- 341
T KW + N + IK V E V K+ +L + A + V + +E V
Sbjct: 7956 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVR-------AVNAIGVSEPSEISENVVA 8008
Query: 342 KEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQV---MWMKDGVELTREDSFKARYRFK 398
K+P LE + V + ++++ V V W KDG E+ D R K
Sbjct: 8009 KDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD----RLTMK 8064
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
D L V+ D G Y + A + K + + D +KAS+
Sbjct: 8065 NDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD--IKASDITKS 8122
Query: 459 KCEVSDEKVTGKWYKNGVEV--------RPSKRITISHVGRFHKL--VIDDVRPEDEGDY 508
C+++ E + G + +R I + +KL + D+ P G+Y
Sbjct: 8123 SCKLTWEPPE---FDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPN--GEY 8177
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYV---PKQEP-PKIHLDCSGKTSENAIVVVAGNKLRL 564
F A++ ++E+K + PKQ P P + ++ T+E
Sbjct: 8178 FFRVK--AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA------------ 8223
Query: 565 DVSITGEPPPV--ATWLKGDEVFTTTEGRTRI----EKRVDCSSFVIESAQREDEGRYTI 618
++IT +PP + + G + +G R E V ++ + + E ++ +
Sbjct: 8224 -MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRV 8282
Query: 619 KVTNPVG---EDVASIFLQVVDVPDPPEAVRITSV---------------GEDWAILVWE 660
+ N G A+ + VD D P+ + TS+ G + + W
Sbjct: 8283 RAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWI 8342
Query: 661 PP----MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL-------- 708
+ + K LV R+K Q + + +++K E L
Sbjct: 8343 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 8402
Query: 709 ----YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y ++V N G+++ P P++ + ED+ T+ KW PP G
Sbjct: 8403 DHGLYMIKV--ENDHGIAKAPCTVSVLDTPGP---PINFVFEDIRKTSVLCKWEPPLDDG 8457
Query: 765 AGGIDGYLVEYC--LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEP 822
I Y +E + EW+ T + C ++V L G LFRV N G P
Sbjct: 8458 GSEIINYTLEKKDKTKPDSEWIVV-TSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8516
Query: 823 ATLAQPVTIREIAEPP----KIRLPRHLRQTYIRKVGEQLNLVVPFQG-----KPRPQVV 873
+++P+ ++ PP K + + + K E + P G +
Sbjct: 8517 C-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTH 8575
Query: 874 WTK-GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W++ + L+ + +V + R A + +G + S D T +
Sbjct: 8576 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP----SDPKTAH-DPISP 8630
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSC 991
GPPI V + T +EW+ P +G EI+GYFV K T EW E+ +
Sbjct: 8631 PGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQY 8689
Query: 992 TVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
TV ++ G +Y RV N G PG ++ +P E + ++ K
Sbjct: 8690 TVKEIREGADYKLRVSAVNAAG-EGPPGETQPVT-------VAEPQEPPAVELDVSVKGG 8741
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
++AG + + V G P P VW K + E+ +D + +I N L I+
Sbjct: 8742 IQ-----IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDAL 8795
Query: 1112 PFDAGTYTCRAVNELGEALAECKLEV 1137
D G Y A N G A ++EV
Sbjct: 8796 RKDHGRYVITATNSCGSKFAAARVEV 8821
Score = 84.3 bits (207), Expect = 6e-16
Identities = 117/447 (26%), Positives = 169/447 (37%), Gaps = 58/447 (12%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++ N K P PL V +VT L W PP G ID Y+V+
Sbjct: 15164 ATNPGGFAKHIFNVKVLDRPGPPEGPL--AVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 15221
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
W +E V+ V L G +FRV+ VN G EP ++PV
Sbjct: 15222 KRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-SEPVLAVNP 15279
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFD 894
PP P++ T I K + +V G P + GG+ + V R
Sbjct: 15280 YGPPDP--PKNPEVTTITK-----DSMVVCWGHPD-----SDGGSEIINYIVERRDKAGQ 15327
Query: 895 ----------TVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPP 936
T + + ++ EYE + EN + V K GPP
Sbjct: 15328 RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPP 15387
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVS 994
N V + ++ + W P DG SEI GY V+ A + EW V + TS T++
Sbjct: 15388 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 15447
Query: 995 DLIVGNEYYFRVYTENICGLSDS---PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
L EY R+Y N GL + PG K R+L I + D R K +
Sbjct: 15448 GLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIEL------DADLR---KVV 15498
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRP 1110
T + A + L ++G P P+V W ++ E + T +Y ++ N+ R
Sbjct: 15499 T------IRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNR- 15551
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
FD+G Y N G A + V
Sbjct: 15552 --FDSGKYILTVENSSGSKSAFVNVRV 15576
Score = 84.3 bits (207), Expect = 6e-16
Identities = 106/412 (25%), Positives = 143/412 (34%), Gaps = 70/412 (16%)
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
++T TL W P G I Y++E W + E +T L G
Sbjct: 21691 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNE 21749
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRLPRHLRQTYIRKV--------G 855
FRV VN G P + PV + + + P I P ++ I G
Sbjct: 21750 YQFRVSAVNKFGVGRPLD-SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGG 21808
Query: 856 EQLNLVVPFQGKPRPQVVWTK--GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
++ + + + + W K P+ +R V ++ EYE
Sbjct: 21809 SEIQQYI-LERREKKSTRWVKVISKRPISETRFKV-------------TGLTEGNEYEFH 21854
Query: 914 VQIENMKDTAT-------IRIRV-VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
V EN I+ R V GPP V V + T +EW P DG EI+
Sbjct: 21855 VMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21914
Query: 966 GYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS------- 1017
GY ++ +W V E T TV+DL G EY FRV N G DS
Sbjct: 21915 GYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTI 21974
Query: 1018 PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKP 1077
V + TA L FK VV AG S L A +G P P
Sbjct: 21975 KAVDRLTAPELDIDANFKQ-------------------THVVRAGASIRLFIAYQGRPTP 22015
Query: 1078 KVVWMK--NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
VW K + + +R D I TL + + DAG YT N G
Sbjct: 22016 TAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNRNDAGKYTLTVENNSG 22063
Score = 84.0 bits (206), Expect = 8e-16
Identities = 108/447 (24%), Positives = 166/447 (37%), Gaps = 71/447 (15%)
Query: 720 GVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEG 779
G Q ++ +P P+ P S ++VT + W+PP G I Y++E G
Sbjct: 10530 GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG 10583
Query: 780 SEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK 839
+ W+P T + V L G +FR+ N+ G S+P + + +
Sbjct: 10584 KDVWMPV-TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP------LVSDSMKAKDR 10636
Query: 840 IRLPRHLRQTYIRKVGEQLNLVV---PFQG-KPRPQVV------WTKGGAPLDTSRVHVR 889
R+P Q + +V + LV P G KP + +K A + +H
Sbjct: 10637 FRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPY 10696
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRV-----VEKAGPPINVMV 941
T R + +YE V EN + D + V + K PP+N
Sbjct: 10697 TK-------FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEA 10749
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT--SCT-----VS 994
+ + + WQ P+ DG S+I+GY V+ EW R HT SC V+
Sbjct: 10750 IDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW----RRANHTPESCPETKYKVT 10805
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL--- 1051
L G Y FRV N G SD V + P K+ R+ P L
Sbjct: 10806 GLRDGQTYKFRVLAVNAAGESDPAHVPE-------------PVLVKD---RLEPPELILD 10849
Query: 1052 -TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110
++ + G + L+ ++G P PKV W K + + +T L IR
Sbjct: 10850 ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNA 10907
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D G Y+ N G K+ V
Sbjct: 10908 AHEDGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 84.0 bits (206), Expect = 8e-16
Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 24/234 (10%)
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++ R A ++ G + V +E + ++ E PP V + +V T+A + W+
Sbjct: 17812 IYYFRVMAENEFG---VGVPVETVD-----AVKAAEPPSPPGKVTLTDVSQTSASLMWEK 17863
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG S ++GY V+ K T +W V E ++ + V+ L G EY FRV N G S
Sbjct: 17864 PEHDGGSRVLGYVVEMQPKGTEKWSIVAE-SKVCNAVVTGLSSGQEYQFRVKAYNEKGKS 17922
Query: 1016 DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHP 1075
D R+L + K D + P P + AG + V G P
Sbjct: 17923 DP--------RVLGVPVIAK-------DLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRP 17967
Query: 1076 KPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
+P + W+K+ +++ + + L+I+ + D G YT A N G A
Sbjct: 17968 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 18021
Score = 82.8 bits (203), Expect = 2e-15
Identities = 100/415 (24%), Positives = 149/415 (35%), Gaps = 52/415 (12%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ D+ +L W P G I Y+VE C +WV A V + V L G
Sbjct: 12629 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTKTSCRVGKLIPG 12687
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV---------- 854
+FRV N G SEP T + V P + P++ R T + K
Sbjct: 12688 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSE---PKNARVTKVNKDCIFVAWDRPD 12744
Query: 855 --GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
G + + K R ++W K L VR++++ V + EY
Sbjct: 12745 SDGGSPIIGYLIERKERNSLLWVKANDTL------VRSTEYPCAGLV------EGLEYSF 12792
Query: 913 SVQIENM-------KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
+ N K T + R+ PP V +V + + W PK DG S+I+
Sbjct: 12793 RIYALNKAGSSPPSKPTEYVTARM--PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKII 12850
Query: 966 GYFVQKADKKTMEWFNVYERNRHT---SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
GYFV+ +W T + L +Y FR +S P
Sbjct: 12851 GYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP-PSEPS 12909
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+ IL + D +A K L V AG + L+ V G P P V W
Sbjct: 12910 DPVTILAENVP------PRIDLSVAMKSLL-----TVKAGTNVCLDATVFGKPMPTVSWK 12958
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
K+ ++ + + + TL + + D+G YT A N G A KL+V
Sbjct: 12959 KDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13013
Score = 82.8 bits (203), Expect = 2e-15
Identities = 92/405 (22%), Positives = 156/405 (38%), Gaps = 35/405 (8%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+++V+ + T+ W PP G I Y+VE S W + + V R + L TG
Sbjct: 19124 IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS-QAVARTSIKIVRLTTG 19182
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT-------YIRKVGEQ 857
+ FRV N G+S + + V + P P+ + T + V +
Sbjct: 19183 SEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDG 19242
Query: 858 LNLVVPF--QGKPRPQVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSV 914
+ V+ + + K R ++W+K L +++ V D ++ R A + +G + S
Sbjct: 19243 GSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSK 19302
Query: 915 QIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
E + + PP V + + ++W P DG ++I GY V++ +
Sbjct: 19303 SCEP--------VPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERREL 19354
Query: 975 KTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
W Y + T V++L Y FRV+ N P S++T I+
Sbjct: 19355 PDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEP--SESTGPIIVKDDV 19412
Query: 1034 FKPFEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDP 1092
P + FR D +VV AG +N + G P P + W K+ +EI E
Sbjct: 19413 EPPRVMMDVKFR----------DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 19462
Query: 1093 KFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG--EALAECKL 1135
+ I + L ++ D G Y N G CK+
Sbjct: 19463 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507
Score = 77.8 bits (190), Expect = 5e-14
Identities = 95/402 (23%), Positives = 156/402 (38%), Gaps = 45/402 (11%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ +V+ TL W PP G I Y++E W + E ++ C L G
Sbjct: 14109 ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQG 14167
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP----KIRLPRHLRQT----YIRKVGE 856
+FRV VN G+ EP ++PV + + PP K + + T + R V +
Sbjct: 14168 NEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14226
Query: 857 QLNLVVPF--QGKPRPQVVWTKG-GAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + + + + + + W + P+ R V + + R +A + +G S
Sbjct: 14227 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14286
Query: 914 VQIEN--MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
++ MKD A GPP N V + +A + W P DG EI GY V+
Sbjct: 14287 EASDSVLMKDAAY-------PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14339
Query: 972 ADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILK 1029
W R T V DL +Y FR+ N G+ + P V + + +
Sbjct: 14340 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVER 14398
Query: 1030 TGITFKPFEYKEHDFRMAPKF-LTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKM 1086
MAP F L + R +V AG S + ++G P P+V W K+ +
Sbjct: 14399 ---------------EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14443
Query: 1087 EIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
++ + I N + L I + +D G + N G+
Sbjct: 14444 NLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGK 14483
Score = 77.4 bits (189), Expect = 7e-14
Identities = 77/267 (28%), Positives = 117/267 (43%), Gaps = 21/267 (7%)
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV----KDEKCFTELFVKEP 344
W K+G I+ S K+ F GK R L I L+D Y + K++ +L V+E
Sbjct: 4779 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838
Query: 345 PVLIVTPLEDQQVFV-GDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
PV V LE++ V G + ++ E+++E V+W KDG + + R G
Sbjct: 4839 PVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDGKIVVEK---PGRIVPGVIGLM 4894
Query: 404 HILIFSDVVQEDRGRYQV-ITNGGQCEAELIVEEKQLEVLQD-----IADLTVKASEQAV 457
L +D D G Y V + N E V K +EV++D I D VK A+
Sbjct: 4895 RALTINDADDTDAGTYTVTVENANNLECSSCV--KVVEVIRDWLVKPIRDQHVKPKGTAI 4952
Query: 458 FKCEVSDEKVTGKWYKNGVEV--RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
F C+++ + KW+K E+ P+ + I G L I + PED +Y +G
Sbjct: 4953 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG- 5011
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIH 542
AKL E +VE + E I+
Sbjct: 5012 -KRYPAKLTLGEREVELLKPIEDVTIY 5037
Score = 77.4 bits (189), Expect = 7e-14
Identities = 139/622 (22%), Positives = 222/622 (35%), Gaps = 82/622 (13%)
Query: 563 RLDVSITGEPPPVATWLKGDEVFTTTEGRTRI-----EKRVDCSSFVIESAQRED----- 612
RLDV T + V WLK D +G +RI E R S F +E+ +
Sbjct: 22179 RLDVVDTSKSSAVLAWLKPDH-----DGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22233
Query: 613 -------EGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITS------VGEDW 654
E + +K N G E +S+ ++ + + IT+ G +
Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22293
Query: 655 AILVWEPPMYDGGKP---VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
I V P+ G+P VT L E + K + R + T T + + + Y +
Sbjct: 22294 TIDV---PI--SGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 22348
Query: 712 RVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
+ N GV S+ P + P+ V V+ + L W P G I Y
Sbjct: 22349 TL--ENTAGVKTFSVTVVVIGRPGPVTGPIE--VSSVSAESCVLSWGEPKDGGGTEITNY 22404
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
+VE G+ W N+ V+R V +L FRV N G S+P A P+
Sbjct: 22405 IVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESA-PIIA 22462
Query: 832 REIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF------------QGKPRPQVVWTKGGA 879
PP P ++ + P+ + K R ++W K
Sbjct: 22463 EHPFVPPSA--PTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVK--- 22517
Query: 880 PLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINV 939
++V ++ V + Y L+ + A+ I P
Sbjct: 22518 ---ENKVPCLECNYKVTGLV-EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP 22573
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM---EWFNV-YERNRHTSCTVSD 995
V +V + + W AP DG S+++GY +++ + W Y TV+
Sbjct: 22574 EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTA 22633
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G+ Y FRV +N G+ +SK + TG EY + + L+
Sbjct: 22634 LSEGDTYEFRVLAKNAAGV-----ISKGSE---STGPVTCRDEYAPPKAELDARLHGDLV 22685
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ AG L+ AV G P+PK++W K E+ K + T I+ D+
Sbjct: 22686 --TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 22743
Query: 1116 GTYTCRAVNELGEALAECKLEV 1137
G YT N G ++V
Sbjct: 22744 GKYTLTVKNASGTKAVSVMVKV 22765
Score = 77.0 bits (188), Expect = 9e-14
Identities = 53/204 (25%), Positives = 88/204 (43%), Gaps = 16/204 (7%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++ E+ PP + + +V + + W+ P+ DG S I+GY V+ K + +W
Sbjct: 15671 VKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC-ATV 15729
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ T T++ LI G EY FRV +N G+SD R L + K D +
Sbjct: 15730 KVTEATITGLIQGEEYSFRVSAQNEKGISDP--------RQLSVPVIAK-------DLVI 15774
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P F V+AG ++ G P P V W K+ + +++ + + + L
Sbjct: 15775 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15834
Query: 1107 IRRPSPFDAGTYTCRAVNELGEAL 1130
I+ D G Y + N GEA+
Sbjct: 15835 IKDACREDVGHYVVKLTNSAGEAI 15858
Score = 74.7 bits (182), Expect = 5e-13
Identities = 97/436 (22%), Positives = 155/436 (35%), Gaps = 49/436 (11%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ A N+ G ++ K P P + + + L W PP G I Y+
Sbjct: 12996 ITAENSSGSKSATIKLKVLDKPGP---PASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052
Query: 773 VEYCLEGSEEWVPAN-TEPVERCGFTVKNLPTGARILFRVVGVNIAGR-----SEPATLA 826
V+ W + T P+ C +V+ L G FR+ N G +EPA
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSC--SVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAK 13110
Query: 827 QPVTIREIAEPPKIR--LPRHLRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLD 882
P +PP I H+ ++ + + + + + + V WTK ++
Sbjct: 13111 NPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VN 13166
Query: 883 TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMK--------DTATIRIRVVEKAG 934
+ RT ++ + EYE V N A G
Sbjct: 13167 RKPIIERT--------LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPG 13218
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEWFNVYERNRHTSCT 992
PP V + ++ + W P DG S I+GY V+ +AD N+ + + T
Sbjct: 13219 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFE 13278
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
V+ L+ +Y FRVY N G SD V + I P + D R
Sbjct: 13279 VTGLMEDTQYQFRVYAVNKIGYSDPSDVPD---KHYPKDILIPPEGELDADLRKT----- 13330
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
++ AG + L V+G P PK+ W K + +R+ I + L +
Sbjct: 13331 ----LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 13386
Query: 1113 FDAGTYTCRAVNELGE 1128
+DAG Y N G+
Sbjct: 13387 YDAGKYILTLENSCGK 13402
Score = 73.6 bits (179), Expect = 1e-12
Identities = 105/414 (25%), Positives = 152/414 (36%), Gaps = 56/414 (13%)
Query: 742 HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNL 801
+L + DV+ T+ W PP G I Y++E C W + V G TV L
Sbjct: 11930 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRL 11988
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G +FRV N G P T ++PV + + P P + KV ++ V
Sbjct: 11989 IEGNEYIFRVRAENKIGTGPP-TESKPVIAKTKYDKPGRPDPPE-----VTKVSKEEMTV 12042
Query: 862 V----PFQG-----------KPRPQVVWT---KGGAPLDTSRVHVRTSDFDTVFFVRQAA 903
V + G K + W K P +V D + F V+
Sbjct: 12043 VWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAEN 12102
Query: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
GE L + KD +E GPP N V + + + W P DG +
Sbjct: 12103 EIGIGEPSLPSRPVVAKDP-------IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12155
Query: 964 IMGYFVQK----ADKKTMEWF---NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
I+GY V+ AD E + N + TV+ L EY FRV +N G+
Sbjct: 12156 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12215
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
+ + KP E E + L+ +V AG L VRG P
Sbjct: 12216 PAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGRPA 12263
Query: 1077 PKVVWMKNKME--IREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
PKV W K ++ +R+ L+ ++ N R D+G Y+ VN GE
Sbjct: 12264 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRD---DSGKYSLTLVNPAGE 12314
Score = 73.6 bits (179), Expect = 1e-12
Identities = 101/421 (23%), Positives = 155/421 (36%), Gaps = 60/421 (14%)
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLP 802
L V VT L W PP + G I Y++E W +TE V+ + V L
Sbjct: 18437 LKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE-VQALNYKVTKLL 18495
Query: 803 TGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP--------KIRLPRHLRQTYIRKV 854
G +FRV+ VN G EP + PVT +PP + T+ R V
Sbjct: 18496 PGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPV 18554
Query: 855 GEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ + + + + + V WTK T +R ++ YE
Sbjct: 18555 DDGGTEIEGYILEKRDKEGVRWTKCNKKTLTD------------LRLRVTGLTEGHSYEF 18602
Query: 913 SVQIENMKDTA-----TIRIRVVEKA---GPPINVMVKEVWGTNALVEWQAPKDDGNSEI 964
V EN ++ R + GPP N V + ++ + W P DG + +
Sbjct: 18603 RVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPV 18662
Query: 965 MGYFVQKADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDS---PG 1019
GY V+ + EW + TV+ L EY FR+ N G+ + PG
Sbjct: 18663 KGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPG 18722
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC--AVRGHPKP 1077
RI I + D R +VVV SA L ++G P+P
Sbjct: 18723 SVVAQERIEPPEIEL------DADLR-----------KVVVLRASATLRLFVTIKGRPEP 18765
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTL-NIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
+V W K + + + + +T+ +L + N+ R FD+G Y N G A +
Sbjct: 18766 EVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR---FDSGRYNLTLENNSGSKTAFVNVR 18822
Query: 1137 V 1137
V
Sbjct: 18823 V 18823
Score = 70.1 bits (170), Expect = 1e-11
Identities = 61/232 (26%), Positives = 96/232 (41%), Gaps = 25/232 (10%)
Query: 905 SDSGEYELSVQIENM-----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
S+ EY V EN T ++ E PP ++ + ++ + + W PK D
Sbjct: 14560 SEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHD 14619
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
G S+I GY ++ K + +W ++ + C V +L G EY F+V N G S +P
Sbjct: 14620 GGSKITGYVIEAQRKGSDQWTHI-TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS-APR 14677
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTPLIDRVVVA--GYSAALNCAVRGHPK 1076
S+ P KE M P+ L + ++V+A G + + V G PK
Sbjct: 14678 ESR-------------PVIVKEQT--MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPK 14722
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
P V W K +++ + LNI D+G Y A N +GE
Sbjct: 14723 PTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 14774
Score = 69.7 bits (169), Expect = 1e-11
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 31/279 (11%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K E+R + I ++ F LV+D+V D G YT + S K F+ ++
Sbjct: 16603 KWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLEN---SSGTKSAFVTVR 16657
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V P P ++L + T ++ VSIT EPP + K
Sbjct: 16658 VLDTPS---PPVNLKVTEITKDS-------------VSITWEPPLLDGGSKIKNYIVEKR 16701
Query: 590 GRTR-----IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF---LQVVDVPDP 641
TR + +S+ I+ Q + + N G + + ++V +VP P
Sbjct: 16702 EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQP 16761
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
P + + V + L W P +DGG + Y+VE + K S++W + + T
Sbjct: 16762 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVI--T 16819
Query: 702 KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP 740
+ +G Y RV AVN G S P P + EP
Sbjct: 16820 NLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 16858
Score = 69.3 bits (168), Expect = 2e-11
Identities = 81/305 (26%), Positives = 128/305 (41%), Gaps = 40/305 (13%)
Query: 429 EAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISH 488
E EL + +++ VL+ A L + + + + EV EK G + R I
Sbjct: 18734 EIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL---------TDRAQIEV 18784
Query: 489 VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
F LVID+V D G Y + + +K F+ ++V LD
Sbjct: 18785 TSSFTMLVIDNVTRFDSGRYNLTLEN---NSGSKTAFVNVRV------------LD---- 18825
Query: 549 TSENAIVVVAGNKLRLD-VSITGEPPPVATWLK-----GDEVFTTTEGRTRIEKRVDCSS 602
S +A V + +++ D V+++ EPP + K ++ TT + I ++
Sbjct: 18826 -SPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT 18884
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVW 659
F IE+ Q + + +N G + + + V V P PP V + V + A + W
Sbjct: 18885 FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 18944
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
E P DGG +TGY+VE + KGS++W E T + G Y RV AVN
Sbjct: 18945 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISG--LTAGEEYVFRVAAVNEK 19002
Query: 720 GVSQP 724
G S P
Sbjct: 19003 GRSDP 19007
Score = 68.2 bits (165), Expect = 4e-11
Identities = 79/289 (27%), Positives = 122/289 (42%), Gaps = 32/289 (11%)
Query: 340 FVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKK 399
FVKE +I+T E FVG VS A WMKDG + ++RF
Sbjct: 4745 FVKEIKDIILTESE----FVGSSAIFECLVSPSTAITTWMKDGSNIRE----SPKHRFIA 4796
Query: 400 DGKRHILIFSDVVQEDRGRYQVITNGGQCE----AELIVEEKQLEVLQDI-ADLTVKASE 454
DGK L DV D G Y + G E A+L+VEE + ++ + ++TV +
Sbjct: 4797 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ 4856
Query: 455 QAVFKCEVSDEKVTGKWYKNG-VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VP 512
CE++ E+ W K+G + V RI +G L I+D D G YT V
Sbjct: 4857 PLYLSCELNKERDV-VWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 4915
Query: 513 DGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEP 572
+ L S+ + +E+ +++ K P + D K AI D++ +
Sbjct: 4916 NANNLECSSCVKVVEVIRDWLVK--PIR---DQHVKPKGTAI-------FACDIA---KD 4960
Query: 573 PPVATWLKG-DEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
P W KG DE+ +T I + + I++A ED Y +++
Sbjct: 4961 TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 5009
Score = 68.2 bits (165), Expect = 4e-11
Identities = 106/473 (22%), Positives = 165/473 (34%), Gaps = 51/473 (10%)
Query: 679 KKGSQ---RWMKLNFEVF-TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPI 734
KKG Q + ++NFE T T + + + A N +G + +
Sbjct: 14728 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP 14787
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
P + P+ ++V+ T W PP G I Y+VE S WV T + R
Sbjct: 14788 GPPTGPIKF--DEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 14844
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV 854
+ L TG FRV N G T A V P P+ T + K
Sbjct: 14845 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQ---VTAVTKD 14901
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF------------VRQA 902
++ P + GG+P+ HV + + + + + +
Sbjct: 14902 SMTISWHEPL----------SDGGSPI--LGYHVERKERNGILWQTVSKALVPGNIFKSS 14949
Query: 903 ARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPK 957
+D YE V ENM + + + ++ PP + + ++W P+
Sbjct: 14950 GLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPE 15009
Query: 958 DDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
G +I Y V+K D W N TVS L Y FRV +N G
Sbjct: 15010 YTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAIS 15069
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
P + IT + + + ++ KF +I + AG + L V G P
Sbjct: 15070 PPSEPSDA-------ITCRD-DVEAPKIKVDVKFKDTVI---LKAGEAFRLEADVSGRPP 15118
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
P + W K+ E+ K I L + + D+G YT A N G A
Sbjct: 15119 PTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 15171
Score = 67.0 bits (162), Expect = 1e-10
Identities = 58/205 (28%), Positives = 84/205 (40%), Gaps = 19/205 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT-SCTVS 994
P ++ VKEV + W PK DG SEI+ Y ++ T ++ V N + TV
Sbjct: 10348 PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVK 10407
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL-TP 1053
L G+ Y +RV NI G K KP K+ +AP L
Sbjct: 10408 GLKEGDTYEYRVSAVNIVGQG-------------KPSFCTKPITCKDE---LAPPTLHLD 10451
Query: 1054 LIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
D++ + G + AL G PKPKV W K++ ++ ED + I L L +
Sbjct: 10452 FRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKR 10511
Query: 1113 FDAGTYTCRAVNELGEALAECKLEV 1137
D+G Y N G C++ V
Sbjct: 10512 SDSGKYCVVVENSTGSRKGFCQVNV 10536
Score = 65.9 bits (159), Expect = 2e-10
Identities = 242/1196 (20%), Positives = 419/1196 (35%), Gaps = 189/1196 (15%)
Query: 41 EDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKS 100
E+Q+ E F+ KP + G V +V G KP + W K G
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP---KPHVYWKKS-----GVPL 1076
Query: 101 GARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDA 160
+ +K S+N + +L I D G Y + V+ K S ++ EA +
Sbjct: 1077 TTGYRYKVSYNKQTG--ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL 1134
Query: 161 SGQSLESFKRTS-------EKKSDTAGELDFSGLLKKREVVEEE-KKKKKKDDDDLGIPP 212
E +T K +TA +S K+ E + +KK KD +
Sbjct: 1135 MKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYV 1194
Query: 213 EIWEL-LKGAKKSEYEKIAFQYGITDLRGMLKR--LKKAKVEVKKSAAFTKKLDPA---Y 266
E E + ++ ++I ++ T L +L+ +K V++ +S A D Y
Sbjct: 1195 EDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNY 1254
Query: 267 QVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRI-LTINKCTLADDA 324
++ G + ++S L + W+K+G+ IK +Y + + R L I D+
Sbjct: 1255 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314
Query: 325 AYEVAVKDEK----CFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMK 380
Y + K C +L+V EP + P + R+ S + +
Sbjct: 1315 IYTAFASNIKGNAICSGKLYV-EPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSP 1373
Query: 381 DGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE 440
+ R + G+R ++E +E QLE
Sbjct: 1374 ARMSPARMSPARMSPARMSPGRR--------LEE-------------------TDESQLE 1406
Query: 441 VLQDIADLTVKASEQAVFKCEVS-----DEKVTGK------WYKNGVEVRP--SKRITIS 487
L V + FKC D KV G+ W+ +G ++ + ++ I
Sbjct: 1407 RLYK----PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIK 1462
Query: 488 HVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSG 547
G L+I P D G++T V A S + + VE V Q P
Sbjct: 1463 EDGT-QSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---LTVEAVEHQVKPMFVEKLKN 1518
Query: 548 KTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE-GRTRIEKRVDCSSFVIE 606
+ + G++L + V TG P P WLK ++ + + RIE ++ I+
Sbjct: 1519 ------VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1572
Query: 607 SAQREDEGRYTIKVTNPVGEDVASIFLQV-VDVPDP-PEAVRITSVGEDWAILVWEPPMY 664
S +D YT N G D + V V+ +P PE I G A + P +
Sbjct: 1573 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPEL- 1631
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
+P+ + G ++W EG LY+
Sbjct: 1632 ---EPL------HLRYGQEQWE------------------EGDLYDKEKQQKPFFKKKLT 1664
Query: 725 SMNTKPFMP------IAPTSEPLHLI--VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
S+ K F P + P +P ++ + D + R N G +D Y V Y
Sbjct: 1665 SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD-YGVAYS 1723
Query: 777 LE------------GSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
+ G++ E+ LP G + L R+ + E A
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH-EGAL 1782
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS 884
+E +P + P +R GE G P+P+V W G + S
Sbjct: 1783 TGVTTDQKEKQKPDIVLYPEPVRVL----EGETARFRCRVTGYPQPKVNWYLNGQLIRKS 1838
Query: 885 R--------VH----VRTSDFDTVFFVRQAARSDSG--EYELSVQIENMKDTATIRIRV- 929
+ +H V +DT V+ A + G E+++ ++I+ +D ++ R
Sbjct: 1839 KRFRVRYDGIHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1897
Query: 930 -----------------VEKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V+K P++ V ++ + + P++ + E+ F
Sbjct: 1898 EPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE--SEELRSKF 1955
Query: 969 VQKADKKTMEWFNVYE-RNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
++ ++ E E ++R + +L+ + +T+ + + K A
Sbjct: 1956 KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKEL-----TEEEKKALAEE 2010
Query: 1028 LKTGI-TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
K I TFKP + + APK + + V G A V G P P+ W KN +
Sbjct: 2011 GKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGV 2070
Query: 1087 EI-REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+I R D + V L IR + D+ + +A+N GE + L V+ Q
Sbjct: 2071 KIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 65.9 bits (159), Expect = 2e-10
Identities = 95/416 (22%), Positives = 157/416 (37%), Gaps = 83/416 (19%)
Query: 267 QVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVF---ENVGKKRILTINKCTLAD 322
+V G ++ +S P ++WF N Q I P+ VF E+ G +L ++
Sbjct: 3429 RVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVD------ 3482
Query: 323 DAAYEVAVKDEKCFTELFVKEPP---VLIVTPLEDQQVFVGDRVEMAVEVS--------- 370
AY C E L VTP + + + +R+E +E+
Sbjct: 3483 --AYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESI-LHERIEQEIEMEMKEFSSSFL 3539
Query: 371 ---EEGA-----QVMWMKDGVELTREDS-FKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
EEG Q+ + + +EL E + ++ +K+G I I +V D
Sbjct: 3540 SAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFI-KEVSNAD------ 3592
Query: 422 ITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPS 481
I+ G D+A L+V + K +W+ NGV + PS
Sbjct: 3593 ISMG------------------DVATLSVTV---------IGIPKPKIQWFFNGVLLTPS 3625
Query: 482 KRITISHVGRFHKLVIDDVRPEDEGDYT-FVPDGYALSLSA---KLN-----FLEIKVEY 532
G H L+I + EDEG+YT + Y ++ + K+N + + E
Sbjct: 3626 ADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETES 3685
Query: 533 VPKQEPPKIHLDCSGKTSENA--IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEG 590
+ K+ C + I G + ++ GEP P TW K ++ T+
Sbjct: 3686 AVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVY 3745
Query: 591 RTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS----IFLQVVDVPDPP 642
T I +F++ QRED G Y K N +GE + + L+ D+ D P
Sbjct: 3746 YTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3801
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 17/203 (8%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
I E+ PP + V + ++A++ W P DG S I GY ++ K + W
Sbjct: 22168 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 22226
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ + TV L+ EY FRV +N G S+ F KE
Sbjct: 22227 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREA-------------FSSVIIKEPQIEP 22273
Query: 1047 APKFLTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104
LT + ++++ AG ++ + G P PKV W +M ++E + IT + T
Sbjct: 22274 TAD-LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTT 22332
Query: 1105 LNIRRPSPFDAGTYTCRAVNELG 1127
L ++ D+G Y N G
Sbjct: 22333 LTVKDSMRGDSGRYFLTLENTAG 22355
Score = 65.5 bits (158), Expect = 3e-10
Identities = 33/94 (35%), Positives = 46/94 (48%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P ++ L + V+ G S L C + G+P P V W + +I F IT G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
R D+G +TC AVNE G C L V+V +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 990
Score = 65.5 bits (158), Expect = 3e-10
Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 18/219 (8%)
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
T + I +++ G P N+ + + T ++W+ P DG S + Y V++ K + +W
Sbjct: 11718 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 11777
Query: 982 VYERNRHTSCTVSDLIVGNEYY-FRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYK 1040
V++ + + + D V N+ Y FRV T+N G SD K ++K + + K
Sbjct: 11778 VHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWV---KTEEVVVKEDLQKPVLDLK 11834
Query: 1041 EHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK--MEIREDPKFLITN 1098
L+ ++ V AG + L VRG P P+V W K+K ++ P+ I
Sbjct: 11835 ----------LSGVL--TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDT 11882
Query: 1099 YQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + D G Y A N G +A + V
Sbjct: 11883 RADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 65.1 bits (157), Expect = 4e-10
Identities = 75/317 (23%), Positives = 124/317 (39%), Gaps = 50/317 (15%)
Query: 269 DRGNKIKLMVEISDPDLTLK--WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G +K + +I + D + + W+ ++++ S KY IL + T DD Y
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25267
Query: 327 EVAV----KDEKCFTELFVK---------------------------EPPVLIVTPLEDQ 355
V ++ + ELFVK E P PL ++
Sbjct: 25268 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25327
Query: 356 QVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQE 414
+VG+ V V ++ V W K G ++ D+ K +Y F+ D + L + V +
Sbjct: 25328 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFESDKGLYQLTINSVTTD 25386
Query: 415 DRGRYQVITNG----GQCEAELIV------EEKQLEVL--QDIADLTVKASEQAVFKCEV 462
D Y V+ C+A+L V + L + + +A+ + + F+ V
Sbjct: 25387 DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRV 25446
Query: 463 SD-EKVTGKWYKNGVEVRPSKRITISHVG-RFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
S T KW K+G + I I H G ++ L I D PED G Y A S S
Sbjct: 25447 SGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTS 25506
Query: 521 AKLNFLEIKVEYVPKQE 537
+ + ++ Y KQE
Sbjct: 25507 CQAHLQVERLRY-KKQE 25522
Score = 60.5 bits (145), Expect = 9e-09
Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 19/196 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYE-RNRHTSCTVS 994
P + V +V + + W+ P DG S + GY ++ T W V + TV+
Sbjct: 23266 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23325
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTP 1053
L G +Y FR+ +N G+S+ R T +T + D R+ P L+
Sbjct: 23326 SLNEGEQYLFRIRAQNEKGVSEP--------RETVTAVTVQ-------DLRVLPTIDLST 23370
Query: 1054 LIDRV--VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
+ + V AG L + G P P W ++RE + + + V L IR +
Sbjct: 23371 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETT 23430
Query: 1112 PFDAGTYTCRAVNELG 1127
D G YT N G
Sbjct: 23431 IRDTGEYTLELKNVTG 23446
Score = 59.7 bits (143), Expect = 2e-08
Identities = 69/295 (23%), Positives = 117/295 (39%), Gaps = 27/295 (9%)
Query: 348 IVTPLEDQQVFVGDRVEMAVEV-SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
I + +V G + V S+ A+V W +GVEL ++S K Y G +
Sbjct: 26004 ITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESSKIHYT-NTSGVLTLE 26060
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
I D +D G Y+ + + EA D A L V + + + DE+
Sbjct: 26061 IL-DCHTDDSGTYRAVCTNYKGEAS------------DYATLDVTGGDYTTYASQRRDEE 26107
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDG---YALSLSAKL 523
V + E+ ++ +S + ++ E + T + Y S SA++
Sbjct: 26108 VPRSVFP---ELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEM 26164
Query: 524 NFLEIKVEYVP-KQEPPKIHLDCSGK--TSENAIVVVAGNKLRLDVSITGEPPPVATWLK 580
++ + + K KI + + T ++ V G R GEP P TWL+
Sbjct: 26165 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26224
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
+V +T+ R ++ S+F I S Q DEG Y++ V N G+ A L +
Sbjct: 26225 KGQVLSTS-ARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26278
Score = 59.3 bits (142), Expect = 2e-08
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 31/222 (13%)
Query: 439 LEVLQDIADLTVKASE----QAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHK 494
L+ +++I D+ + SE A+F+C VS W K+G +R S + G+ K
Sbjct: 4743 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802
Query: 495 LVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAI 554
L I DV+ D G+YT V L K + ++ VE +P + KT E +
Sbjct: 4803 LHIIDVQLSDAGEYTCV---LRLGNKEKTSTAKLVVEELPVR---------FVKTLEEEV 4850
Query: 555 VVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 614
VV G L L + E V W K ++ GR + I A D G
Sbjct: 4851 TVVKGQPLYLSCELNKERDVV--WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAG 4908
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
YT+ V N + +S V++ V DW +
Sbjct: 4909 TYTVTVENANNLECSS-------------CVKVVEVIRDWLV 4937
Score = 59.3 bits (142), Expect = 2e-08
Identities = 118/608 (19%), Positives = 216/608 (35%), Gaps = 90/608 (14%)
Query: 6 PAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPT------GVFLKKPD 59
P K+P+ P+ EA ++P+ + P+ SPT +PT + + P
Sbjct: 26291 PPRVKSPE----PRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPP 26346
Query: 60 SVS----VETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGARFSFKESHNSAS 114
++ E K+ + V + + W+K GK L K F F H SA
Sbjct: 26347 KITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL----KENGHFQF---HYSAD 26399
Query: 115 NVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEA-----PRQDASGQSLESFK 169
Y EL I + D+G Y E+ + +A + ++ +S +
Sbjct: 26400 GTY--ELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQ 26457
Query: 170 RTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLG----------IPPEIWELLK 219
+T+E E + + V+ + D + P IW
Sbjct: 26458 KTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIW---- 26513
Query: 220 GAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKL-DPAYQVDRGNKIKLMV 278
K + +Y +++ +G L+ K + S +T + + A V K+ +
Sbjct: 26514 -TKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26571
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
I D + + EI P K V + ++ L + +++ + E E+
Sbjct: 26572 -IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 26630
Query: 339 LFVKEPPVLIVTPLE---------------------------DQQVFVGDRVEMAVEVSE 371
L +E T LE Q+ + + + ++ +
Sbjct: 26631 LISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANI 26690
Query: 372 EGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI--TNGG-- 426
GA V W+ +GVELT + YR+ G L D G I T G
Sbjct: 26691 AGATDVKWVLNGVELTNSE----EYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIV 26746
Query: 427 QCEAELIVEEKQLEV---LQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSK 482
+C+ +L + ++ + + + + +F CE+S E +W+KN + + S
Sbjct: 26747 KCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISS 26806
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
++IS + L I + D G YT + SA + + + + P +E +
Sbjct: 26807 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSRE---VV 26863
Query: 543 LDCSGKTS 550
L SG TS
Sbjct: 26864 LRTSGDTS 26871
Score = 56.6 bits (135), Expect = 1e-07
Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 605 IESAQREDEGRYTIKVTNPVGEDVAS------IFLQVVDVPDPPEAVRITSVGEDWAILV 658
+++ + E ++ +K N +G S + ++ P PP R+ + L
Sbjct: 12085 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 12144
Query: 659 WEPPMYDGGKPVTGYLVERKKK-----GSQRWMKLNFEV-FTETTYESTKMIEGILYEMR 712
W P+YDGG P+ GY+VE + K + W + N + T + E YE R
Sbjct: 12145 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 12204
Query: 713 VFAVNAIGVSQPS 725
V A N +G+ +P+
Sbjct: 12205 VCAQNQVGIGRPA 12217
Score = 56.2 bits (134), Expect = 2e-07
Identities = 50/208 (24%), Positives = 85/208 (40%), Gaps = 25/208 (12%)
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ-KADKKTMEWFNVYERNRHTSCTV 993
PP + V E+ +A + W P DG ++I GY + +++ + + Y + S V
Sbjct: 12429 PPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVV 12488
Query: 994 SDLIVGNEYYFRVYTENICGLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF 1050
+ L G +Y FRV N G+S ++ GV Y+ + + PK
Sbjct: 12489 TGLKEGKKYKFRVAARNAVGVSLPREAEGV------------------YEAKEQLLPPKI 12530
Query: 1051 LTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
L P +++ + AG + V G P P W K + E+ + L I+
Sbjct: 12531 LMP--EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 12588
Query: 1110 PSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D+G Y+ A N G + K+ V
Sbjct: 12589 VTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 55.1 bits (131), Expect = 4e-07
Identities = 53/239 (22%), Positives = 92/239 (38%), Gaps = 24/239 (10%)
Query: 907 SGEYELSVQIENMKDTATIRIR-----VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGN 961
S E E S ++ AT++I+ ++++ GP I+ + + +
Sbjct: 4335 SEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA 4394
Query: 962 SEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVS 1021
E+ YF K ++ + ++N +T V D + ++ E +C + G +
Sbjct: 4395 KEVNWYFENKLVPSDEKFKCLQDQNTYT--LVIDKVNTEDHQ----GEYVCEALNDSGKT 4448
Query: 1022 KNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVW 1081
+A++ R AP + V G+ A C ++ P + W
Sbjct: 4449 ATSAKLTVVK-------------RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 4495
Query: 1082 MKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
K EI E K I + + + +L I R D G YTC+A NE G L V VP
Sbjct: 4496 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4554
Score = 55.1 bits (131), Expect = 4e-07
Identities = 59/225 (26%), Positives = 87/225 (38%), Gaps = 30/225 (13%)
Query: 927 IRVVEKAGPPIN---VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
I V+ GPP + + E + ++W+ P+ +G S I GY ++K ++ V
Sbjct: 8914 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8973
Query: 984 ERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+R TS V +L Y FRV N G S+ P + P
Sbjct: 8974 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE-PSL---------------PLNVVIQ 9017
Query: 1043 DFRMAPKFLTPLIDR----VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL--- 1095
D + P L R V AG + V G P PK+ W KN+ I + L
Sbjct: 9018 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 9077
Query: 1096 ---ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + L+I + D GTYT A N LG +EV
Sbjct: 9078 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9122
Score = 55.1 bits (131), Expect = 4e-07
Identities = 72/327 (22%), Positives = 125/327 (38%), Gaps = 24/327 (7%)
Query: 518 SLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVAT 577
+L + + EI PK + P I + N V N L +TG P P+
Sbjct: 24531 NLGGESEWSEISEPITPKSDVP-IQAPHFKEELRNLNVRYQSNAT-LVCKVTGHPKPIVK 24588
Query: 578 WLKGDEVFTTTEGRTRIEK-RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV- 635
W + + + RI++ + +I S +D Y ++ TN G + L+V
Sbjct: 24589 WYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Query: 636 ----VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE 691
+ +P E + + + P GKP ++ +K +++
Sbjct: 24649 VPAKIHLPKTLEGMGAVHALRGEVVSIKIP---FSGKPDP--VITWQKGQDLIDNNGHYQ 24703
Query: 692 VFTETTYESTKMIEGILYEMRVFAV----NAIGVSQPSMNTKPFMPIAPTSEPLHLI-VE 746
V ++ S G+ + F V N G+ Q ++ + +A +P + V
Sbjct: 24704 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE----LDVADVPDPPRGVKVS 24759
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
DV+ + L W P G I Y+VE C +E W+ R +TV NL
Sbjct: 24760 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR--YTVINLFGKTS 24817
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIRE 833
FRV+ N G S+P+ ++P +E
Sbjct: 24818 YQFRVIAENKFGLSKPSEPSEPTITKE 24844
Score = 51.2 bits (121), Expect = 5e-06
Identities = 68/310 (21%), Positives = 115/310 (37%), Gaps = 56/310 (18%)
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ--VITN 424
+E ++ QV W +L + ++ Y +DG IL D+ + D G Y+ V+ +
Sbjct: 25219 IENYDQSTQVTWYFGVRQLENSEKYEITY---EDGVA-ILYVKDITKLDDGTYRCKVVND 25274
Query: 425 GGQCE--AELIVE---------------------------EKQLEVLQDIADLTVKASEQ 455
G+ AEL V+ E+ E + + T E
Sbjct: 25275 YGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN 25334
Query: 456 AVFKCEVS---DEKVTGKWYKNGVEVRPS---KRITISHVGRFHKLVIDDVRPEDEGDYT 509
F ++ + VT WYK+G +++P K+ T ++L I+ V +D+ +YT
Sbjct: 25335 VRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 25392
Query: 510 FVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA----GNKLRLD 565
V S K V PP D + + ++ A G + +
Sbjct: 25393 VVARNKYGEDSCKAKLT------VTLHPPPT---DSTLRPMFKRLLANAECQEGQSVCFE 25443
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 625
+ ++G PPP W K + + I + +D + I ED G Y + TN G
Sbjct: 25444 IRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25503
Query: 626 EDVASIFLQV 635
LQV
Sbjct: 25504 STSCQAHLQV 25513
Score = 49.3 bits (116), Expect = 2e-05
Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 17/204 (8%)
Query: 443 QDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKR--ITISHVGRFHKLVIDD 499
Q + + V A F+ +S V W+++G + S + IS KL I
Sbjct: 10 QPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPA 69
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V + G Y+ + ++ L +K E P ++ ++ V G
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELL-VKAETAPPNFVQRLQ----------SMTVRQG 118
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+++RL V +TG P PV + + G E+ ++ + +I + D S +I A ED G Y++
Sbjct: 119 SQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 619 KVTNPVGEDVASIFLQVVDVPDPP 642
TN VG ++ L V + P
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVP 200
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Query: 351 PLEDQQVFVGDRVEMAVEVSEEGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFS 409
PL+ V G +S +V W +DG ++ + F DG+ + I +
Sbjct: 11 PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRAKLTIPA 69
Query: 410 DVVQEDRGRYQV-ITNG-GQCE--AELIVEEKQL--EVLQDIADLTVKASEQAVFKCEVS 463
V + + GRY + TNG GQ AEL+V+ + +Q + +TV+ Q + V+
Sbjct: 70 -VTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 464 DEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
K+Y++G E++ S IS G + L+I + PED G Y+
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/94 (30%), Positives = 40/94 (42%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P+ L L V +G A + G P+PK+ W K + + K + TL +
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P DA YTC A N+ G A L V VP+
Sbjct: 3253 IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR---EDPKFLITNYQGVLT 1104
P+F PL ++ G + + HP+P V W K+ +I+ D K+ + +G+
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L I + D YT A N+ GE + KL V
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 48.5 bits (114), Expect = 4e-05
Identities = 76/332 (22%), Positives = 117/332 (35%), Gaps = 51/332 (15%)
Query: 243 KRLKKAKVEVKKSAAFTKKLDP-------AYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQ 294
++ + K EV FT P +++V G + ++ + S P +KW+ NG
Sbjct: 25981 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26040
Query: 295 EIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLED 354
E++ SSK + N L I C D Y + K + L VT
Sbjct: 26041 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYA----TLDVTG--- 26093
Query: 355 QQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGK-------RHILI 407
GD A + +E ELTR +++ A FKK + R +
Sbjct: 26094 -----GDYTTYASQRRDEEVPRSVFP---ELTRTEAY-AVSSFKKTSEMEASSSVREVKS 26144
Query: 408 FSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE---------------VLQDIADLTVKA 452
+E Y+ + A L EEK LE +L +TV
Sbjct: 26145 QMTETRESLSSYEHSASAEMKSAAL--EEKSLEEKSTTRKIKTTLAARILTKPRSMTVYE 26202
Query: 453 SEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
E A F C+ E V T W + G + S R ++ I V+ DEG+Y+ V
Sbjct: 26203 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVV 26262
Query: 512 PDGYALSLSAKLNFLEIKVEYVPK--QEPPKI 541
+ A+ K K PP++
Sbjct: 26263 VENSEGKQEAEFTLTIQKARVTEKAVTSPPRV 26294
Score = 47.8 bits (112), Expect = 6e-05
Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P +TPL D V G A C V G KV W +I+ F +T ++ L I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
P D GTYT A N +G+ + L +
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 2/101 (1%)
Query: 1039 YKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI--REDPKFLI 1096
+K+ P F+ PL V G + + V G PKP++ W N+ I +D F
Sbjct: 3410 FKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHF 3469
Query: 1097 TNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
G+ + I AG Y+C+A N GEA L V
Sbjct: 3470 EESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/91 (32%), Positives = 40/91 (43%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
AP+ + V G + V+ P +V W N +E++E K TN GVLTL
Sbjct: 26001 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 26060
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
I D+GTY N GEA L+V
Sbjct: 26061 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 46.2 bits (108), Expect = 2e-04
Identities = 47/176 (26%), Positives = 78/176 (44%), Gaps = 12/176 (6%)
Query: 341 VKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKD 400
+KE +I TPL D GD V + ++ +V W + + ++ FK +D
Sbjct: 4363 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLVPSDEKFKCL----QD 4417
Query: 401 GKRHILIFSDVVQED-RGRY--QVITNGGQC--EAELIVEEKQLEVLQ-DIADLTVKASE 454
+ L+ V ED +G Y + + + G+ A+L V ++ V++ I L V
Sbjct: 4418 QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGH 4477
Query: 455 QAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
A F CE+ S V +W+K G E+ S + +I L I + D G+YT
Sbjct: 4478 LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4533
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1032 ITFKPFEYKEHDFRMAP--KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR 1089
+T K F+ + F P +F PL D+ V G +A L C V KV W KN EI
Sbjct: 5895 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEIL 5953
Query: 1090 EDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
+ K+ I V L I +P D TYTC A
Sbjct: 5954 KSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5986
Score = 44.7 bits (104), Expect = 5e-04
Identities = 48/210 (22%), Positives = 76/210 (36%), Gaps = 28/210 (13%)
Query: 457 VFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGY 515
V K E D+ WY ++ S++ I++ L + D+ D+G Y V + Y
Sbjct: 25216 VCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDY 25275
Query: 516 ALSLSAKLNFL----EIKVEYVPK---------------QEPPKIHLDCSGKTSENAIVV 556
S F+ E+ Y + + PP+ L KT+
Sbjct: 25276 GEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA------ 25329
Query: 557 VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSF--VIESAQREDEG 614
G +R V+IT P P TW K + + + D + I S +D+
Sbjct: 25330 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 25389
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEA 644
YT+ N GED L V P P ++
Sbjct: 25390 EYTVVARNKYGEDSCKAKLTVTLHPPPTDS 25419
Score = 44.3 bits (103), Expect = 7e-04
Identities = 28/91 (30%), Positives = 42/91 (46%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P F+ L V G L V G P P V + ++ EI+ F I+ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
P D+GTY+ A N +G A + +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 1/91 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF-LITNYQGVLTLN 1106
P FL L G A V G P P V W K ++ + +I N G T
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ P D+G Y C+A N LGE+ +L V
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED--PKFLITNYQGVLT 1104
AP F PL VV+ G +A + G P P+V W ++ I P I+ G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L I + ++G Y+ +A N G+A + +L V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/170 (22%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
++VV+ G+ + I+G P P +W + G + T+T +I + I + +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
+ GRY++K TN G+ ++ L V PP V+ ++ V + VT
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-----SMTVRQGSQVRLQVRVT 128
Query: 672 GY---LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
G +V+ + G++ L+F++ E S + E + ++VNA
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNA 178
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/285 (21%), Positives = 104/285 (36%), Gaps = 41/285 (14%)
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDR-----GRYQVITNGGQCEAELIVEEKQLEVLQ 443
D++K+ + + + I V+E+R GR +T + A + + ++
Sbjct: 842 DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVS 901
Query: 444 DIADLTVKASEQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRP 502
+ ++TV E +C +S T WY+ ++ S I+ +L+I +
Sbjct: 902 GLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFA 961
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKV-EYVPKQ----------------EPPKIHLDC 545
ED G +T A ++S +L ++V E K+ E + +
Sbjct: 962 EDSGRFTCSAVNEAGTVSTSC-YLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1020
Query: 546 SGKTSENA--------------IV--VVAGNKLRLDVSITGEPPPVATWLKGDEVFTT-T 588
+ T E A +V +V G + + G P P W K TT
Sbjct: 1021 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGY 1080
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
+ K+ VI +D G YTI V N GE AS L
Sbjct: 1081 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 40.4 bits (93), Expect = 0.010
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
+ V+ G + L+ I+G P P TW + D ++ ++ + + + + + +I A ED
Sbjct: 906 VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLMIREAFAED 963
Query: 613 EGRYTIKVTNPVGEDVASIFLQV 635
GR+T N G S +L V
Sbjct: 964 SGRFTCSAVNEAGTVSTSCYLAV 986
Score = 39.3 bits (90), Expect = 0.022
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 4/104 (3%)
Query: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI--REDPK 1093
P ++ P F+ + + + G A L+ V G PKPK+ W N + + D K
Sbjct: 3570 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3629
Query: 1094 FLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
F+ L + + D G YTC A N+ G+ + L++
Sbjct: 3630 FVFDGDDHSLIILFTKLE--DEGEYTCMASNDYGKTICSAYLKI 3671
Score = 38.9 bits (89), Expect = 0.028
Identities = 19/61 (31%), Positives = 31/61 (50%)
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+V W ++ K+ IT GV L ++ + D GTY C+ VN+ GE + +L V
Sbjct: 25227 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286
Query: 1138 R 1138
+
Sbjct: 25287 K 25287
Score = 38.1 bits (87), Expect = 0.048
Identities = 48/197 (24%), Positives = 83/197 (42%), Gaps = 29/197 (14%)
Query: 287 LKWFKNGQEIK----PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEK----CFTE 338
+ WF++GQ I P + F + K LTI T A+ Y + + E
Sbjct: 37 VSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTAE 94
Query: 339 LFVKEP--PVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM-WMKDGVELTREDSFKARY 395
L VK P V L+ V G +V + V V+ V+ + +DG E+ F+
Sbjct: 95 LLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQ--- 151
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQV-ITNG---GQCEAELIVEEKQLEVLQDIADLTVK 451
++G + L+ ++ ED G Y V TN AEL+V+ ++ ++ K
Sbjct: 152 -ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--------EVPAK 202
Query: 452 ASEQAVFKCEVSDEKVT 468
++ V ++S+ + T
Sbjct: 203 KTKTIVSTAQISESRQT 219
Score = 37.7 bits (86), Expect = 0.063
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 14/105 (13%)
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
T+R + PP+ LP + + Y VGE + V P P V W K G ++
Sbjct: 25310 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIK 25359
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG 934
D D + SD G Y+L++ D A + K G
Sbjct: 25360 PGDNDK----KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 25400
Score = 37.4 bits (85), Expect = 0.082
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 21/97 (21%)
Query: 237 DLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQE 295
DLRG+ ++L AK G+ IK+ + + P T+ W K Q
Sbjct: 14694 DLRGIYQKLVIAKA--------------------GDNIKVEIPVLGRPKPTVTWKKGDQI 14733
Query: 296 IKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKD 332
+K + + FE IL IN+C +D Y + ++
Sbjct: 14734 LKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14770
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 22/93 (23%)
Query: 1006 VYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSA 1065
VYT + G K +AR+ TGI K F++PL D+ V G +A
Sbjct: 5181 VYTAEVEG-------KKTSARLFVTGIRLK--------------FMSPLEDQTVKEGETA 5219
Query: 1066 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITN 1098
C + H K VVW KN ++ LI++
Sbjct: 5220 TFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISS 5251
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 1/82 (1%)
Query: 252 VKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKK 310
V S KL V G ++ I P T KW +G EIK Y E
Sbjct: 11134 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11193
Query: 311 RILTINKCTLADDAAYEVAVKD 332
+LTI C D Y++ V +
Sbjct: 11194 SVLTIKNCLRRDTGEYQITVSN 11215
Score = 36.2 bits (82), Expect = 0.18
Identities = 57/267 (21%), Positives = 99/267 (37%), Gaps = 40/267 (14%)
Query: 874 WTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W + G L T+ + + + D GEY + ++ K +A +++ V+
Sbjct: 2606 WLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVKI 2663
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT 992
N+ V E VE P G I V ++++K + + + S
Sbjct: 2664 KKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEK----YAISVKGTIYSLR 2719
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
+ + + +E VY + L S + T +I+K PK +T
Sbjct: 2720 IKNCAIVDE---SVYGFRLGRLGASARLHVETVKIIKK-----------------PKDVT 2759
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
L + V S + H V W +EI+ K + + + V L ++ SP
Sbjct: 2760 ALENATVAFEVSVS-------HDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2812
Query: 1113 FDAGTYTCRAVNELGEALAECKLEVRV 1139
DAG YT V +L ECK ++ V
Sbjct: 2813 SDAGEYTA-VVGQL-----ECKAKLFV 2833
Score = 36.2 bits (82), Expect = 0.18
Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P F L + G S V G P P + W K+ + P I ++G+
Sbjct: 25418 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25476
Query: 1103 --LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+IR P D G Y A N G + L+V
Sbjct: 25477 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25513
Score = 34.7 bits (78), Expect = 0.53
Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 243 KRLKKAKVEVKKSAA--FTKKLDPAYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPS 299
K AK+ V K AA +K++P +V G+ K EI S P++ +WFK G+EI S
Sbjct: 4447 KTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFKAGREIYES 4505
Query: 300 SKYVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKEP 344
K + L I + + D Y +E C L V P
Sbjct: 4506 DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4554
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDTVFFVRQAAR 904
Q+ + G G P P+V W + G + TS V + SD + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
++SG Y L + + T+T + V + PP
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 268 VDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G ++L++ I+ P WF G +++ S + E K LTI + T+ D Y
Sbjct: 23378 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEY 23437
Query: 327 EVAVKD 332
+ +K+
Sbjct: 23438 TLELKN 23443
Score = 32.3 bits (72), Expect = 2.6
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 873 VWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
VW K G + S RVH+ + + + D+G Y ++ + + + + V+
Sbjct: 2341 VWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400
Query: 932 KAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
P +V V E GT A++E + D S
Sbjct: 2401 VITPLKDVNVIE--GTKAVLECKVSVPDVTS 2429
Score = 32.0 bits (71), Expect = 3.4
Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 268 VDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K+ + V + P T+ W K+G+E+K S + +N L + K AD Y
Sbjct: 8026 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 8085
Query: 327 EVAVKDE 333
+ ++++
Sbjct: 8086 TITLENK 8092
Score = 31.6 bits (70), Expect = 4.5
Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 6/122 (4%)
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK-----FLTPLIDRVVVAGY 1063
+N+C L ++++A I+ I E H F + F L D V
Sbjct: 2085 DNVCELVIRDVTAEDSASIMVKAINIAG-ETSSHAFLLVQAKQLITFTQELQDVVAKEKD 2143
Query: 1064 SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAV 1123
+ A P KV W K+ ME+ E K+ + + + V L+I DA Y+C V
Sbjct: 2144 TMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 1124 NE 1125
+
Sbjct: 2204 ED 2205
Score = 31.6 bits (70), Expect = 4.5
Identities = 60/257 (23%), Positives = 100/257 (38%), Gaps = 50/257 (19%)
Query: 45 PTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGAR 103
PT +F + + + G+ +V+G +P PT+KW K G+ L LG
Sbjct: 25416 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG--IPP-PTLKWEKDGQPLSLGPNI--- 25469
Query: 104 FSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPR-QDASG 162
E + + Y LHI + D GYYR+ SC ++ VE R +
Sbjct: 25470 ----EIIHEGLDYYA--LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEF 25523
Query: 163 QSLESFKRTSEKKSDTAGELDFSGLLKKREVV--EEEKKKKKKDDDDLGIPPEIWELLKG 220
+S E +R +K+ D L + +L E V + K+ ++ L P + +KG
Sbjct: 25524 KSKEEHERHVQKQIDKT--LRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKG 25581
Query: 221 ------AKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKI 274
+K E K+ Y + + R + K+ +E +I
Sbjct: 25582 EFRLEIEEKKEERKLRMPYDVPEPR----KYKQTTIE------------------EDQRI 25619
Query: 275 KLMVEISDPDLTLKWFK 291
K V +SD +KW+K
Sbjct: 25620 KQFVPMSD----MKWYK 25632
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 261 KLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCT 319
KL V G KI+L ++ P+ + W K +K + ENV KK +TI
Sbjct: 7323 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSK 7382
Query: 320 LADDAAY 326
+D Y
Sbjct: 7383 RSDTGTY 7389
Score = 30.8 bits (68), Expect = 7.7
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+FL PL D V A C + KV W K+ EI++ K+ I + V L I
Sbjct: 6003 EFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVIN 6061
Query: 1109 RPSPFDAGTYTC 1120
+ D Y+C
Sbjct: 6062 KCLLDDEAEYSC 6073
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 275 bits (704), Expect = 1e-73
Identities = 222/790 (28%), Positives = 337/790 (42%), Gaps = 43/790 (5%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
++S +KW++NG+EIK KY FE G L I C L D+ Y V+D K
Sbjct: 6348 QLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRAR 6407
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
LFV+E PV I+ P +D G V E++++ +V W+++ + + + D +++
Sbjct: 6408 LFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD----KHQMM 6463
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEA--ELIVEEKQLEVLQDIA-----DLTVK 451
+GK H L D+ D+G Y+ I + A EL K QD+ LT+
Sbjct: 6464 SEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMV 6523
Query: 452 ASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
A K E +W+K E P TI I + + D+G Y V
Sbjct: 6524 VPYDAYPKAEA-------EWFK---ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIV 6573
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
+N I V + D + + G+K+ + +
Sbjct: 6574 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKI-IGYVVERR 6632
Query: 572 PPPVATWLKGDEVFTTTEGR-TRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS 630
TW+ + + E T ++K F + + R G ++ NPV + S
Sbjct: 6633 DIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE-PVETDNPV--EARS 6689
Query: 631 IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRW---MK 687
+ DVP PP V IT V L WEPP YDGG +T Y++E + K S RW M
Sbjct: 6690 KY----DVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 6745
Query: 688 LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHL 743
+ E + T T ++EG Y RV A N IGV +PS T PF+ PI S P++L
Sbjct: 6746 VRAEDLSATV---TDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNL 6801
Query: 744 IVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPT 803
D T ++ LKW PP + G I GY++E C EG + W+ N + V + V L
Sbjct: 6802 TSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEK 6861
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP 863
G + L+RV N AG S+P+ + P+T + P + L + V + ++VP
Sbjct: 6862 GNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVI-VPNPITILVP 6920
Query: 864 FQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
G PRP W G L+T RV ++T + + RSD G Y L ++ +
Sbjct: 6921 STGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 6980
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I + V+ + P + ++ + + W+ P DDG S + GY V+K + W V
Sbjct: 6981 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 7040
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+ TV DL+ G EY F+V N CG + V + + P K
Sbjct: 7041 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWR 7100
Query: 1043 DFRMAPKFLT 1052
D FLT
Sbjct: 7101 DRTANSIFLT 7110
Score = 274 bits (701), Expect = 3e-73
Identities = 167/480 (34%), Positives = 243/480 (50%), Gaps = 13/480 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP+I LD + +V+ A LRL V+I G P P W K + + T R +IE
Sbjct: 18606 EPPEIELDADLR---KVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTD---RAQIEV 18659
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ VI++ R D GRY + + N G A + ++V+D P P + I V +D
Sbjct: 18660 TSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVT 18719
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L WEPP+ DGG +T Y+VE+++ + + + T+TT+ + EG Y RV A
Sbjct: 18720 LSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC-TKTTFRIENLQEGCSYYFRVLAS 18778
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G+ P+ T+P P P + + DVT T T+KW P G I GY+VE
Sbjct: 18779 NEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 18838
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
+GSE+W + V+ T+ L G +FRV VN GRS+P L PV R+I
Sbjct: 18839 TKGSEKW--STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEI 18896
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDT 895
P + LP H T+ K EQL + VPF+G+P+ V W K G L +T+RV+V +S T
Sbjct: 18897 KPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT 18953
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++A++ D G YEL V T I I V+++ GPP + + EV + + W
Sbjct: 18954 SLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNP 19013
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG +I Y V+K + + W V + TS + L G+EY FRV EN G S
Sbjct: 19014 PEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19073
Score = 265 bits (678), Expect = 1e-70
Identities = 169/568 (29%), Positives = 272/568 (47%), Gaps = 23/568 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P++ LD + IVV AG R+ + G P P TW + + FT + +I
Sbjct: 17521 KLEAPELDLDSELR---KGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD---KVQI 17574
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
EK V+ + I++ R D G+Y +K+ N G A + ++V+D P PP+ + + V +D
Sbjct: 17575 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDS 17634
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A LVWEPP+ DGG V Y++++++ + + ++ + ++T+++ + EG +Y RV
Sbjct: 17635 AFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKC-SKTSFKVENLTEGAIYYFRVM 17693
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N GV P P S P + + DV+ T+ +L W P G + GY+VE
Sbjct: 17694 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17753
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G+E+W V C V L +G FRV N G+S+P L PV +++
Sbjct: 17754 MQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 17811
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDF 893
P ++LP + TY + GE L + +P G+PRP + W K G PL T+RV+V +
Sbjct: 17812 TIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETAT 17868
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
TV +++ + D G+Y ++ T + + V+EK GPP+ V EV ++
Sbjct: 17869 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 17928
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ P G +I Y V+K D T W V T+ ++ L G EY FR++ EN
Sbjct: 17929 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRY 17988
Query: 1013 GLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC 1069
G S DS V + G PF +M ++ P+ D G + +
Sbjct: 17989 GKSAPLDSKAVIVQYP-FKEPGPPGTPFVTSISKDQMLVQWHEPVND-----GGTKIIGY 18042
Query: 1070 AVRGHPKPKVVWMKNKMEIREDPKFLIT 1097
+ K ++W+K +D KF T
Sbjct: 18043 HLEQKEKNSILWVKLNKTPIQDTKFKTT 18070
Score = 261 bits (668), Expect = 2e-69
Identities = 175/561 (31%), Positives = 269/561 (47%), Gaps = 37/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+ G ++R S+R+T+ + KL I + D G+YT + S IKV
Sbjct: 23275 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 23329
Query: 531 EYVPKQEPPK--IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKG---DE 583
+ K PP I +D TS ++I+ EPP + L G ++
Sbjct: 23330 IILDKPGPPTGPIKIDEIDATS---------------ITISWEPPELDGGAPLSGYVVEQ 23374
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--VGEDVASIFLQV---VDV 638
G + + V S+F +E + + TN +G + S ++ + +
Sbjct: 23375 RDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRI 23434
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PPE ++I V D L W PP DGG VTGY+VERK+ + RW+++N T T Y
Sbjct: 23435 PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRY 23494
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
ST + EG+ YE RV A+NA G +PS +KP + PIAP +P + V D T T+ +L
Sbjct: 23495 RSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 23554
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
W P G + GYL+E EW NT P + +T+ +LP GA FRV+ N
Sbjct: 23555 AWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACN 23614
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
G EPA + V + E+ E P L ++ + G + L +P +GKP P WT
Sbjct: 23615 AGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWT 23674
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K G + + R + TS+ T +++A R DSG Y+L ++ + K I++RV+
Sbjct: 23675 KEGQDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNS 23733
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + V W+ P DDG ++I+GY +++ + W+ + R R TS V
Sbjct: 23734 PEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVK 23793
Query: 995 DLIVGNEYYFRVYTENICGLS 1015
L EY+FRV EN G+S
Sbjct: 23794 GLKENVEYHFRVSAENQFGIS 23814
Score = 252 bits (644), Expect = 1e-66
Identities = 177/599 (29%), Positives = 286/599 (47%), Gaps = 32/599 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ VKA E +++ + W K+G+E+ R I L + D D G
Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTG 19361
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A + S +N + + K PP L+ +G T+E + + + + D
Sbjct: 19362 QYVLTLKNVAGTRSVAVN-----CKVLDKPGPPAGPLEINGLTAEKCSL--SWGRPQEDG 19414
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP--V 624
+ V +T EG ++ +S + + +E + + N V
Sbjct: 19415 GADIDYYIVEKRETSHLAWTICEGELQM------TSCKVTKLLKGNEYIFRVTGVNKYGV 19468
Query: 625 GEDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKG 681
GE + S+ ++ +D VP PP ++ ITSV ++ L W P DGG ++GY++ER++K
Sbjct: 19469 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19528
Query: 682 SQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----PIAPT 737
S RW+++N + + +ST + EG YE RV+A NA G+S PS T P + P+
Sbjct: 19529 SLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPS-ETSPLIRAEDPVFLP 19587
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
S P + D TT T+ W P G I GY VEY +W + + + +T
Sbjct: 19588 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYT 19646
Query: 798 VKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQ 857
+ L TGA +FRV VN G S+P+ + P +E E P + +R+T I K G
Sbjct: 19647 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19706
Query: 858 LNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ VPF+G+P P V+W+K L T R +V T+D T + A R+DSG+Y L++Q
Sbjct: 19707 FTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNV 19765
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ T+ ++V++ GPP N+ V++V +A++ W P++DG + + Y ++K +
Sbjct: 19766 LSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKK 19825
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
W +V S V++L G YYFRV EN G+ G+ T +K IT KP
Sbjct: 19826 AWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV----GIPAETKEGVK--ITEKP 19878
Score = 249 bits (637), Expect = 8e-66
Identities = 181/600 (30%), Positives = 287/600 (47%), Gaps = 38/600 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
LTVKA V + + T W K+G ++P++ I ++ L + V +D G
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
DYT + + S SA IK++ + K PP V NK+ D
Sbjct: 12868 DYTITAENSSGSKSAT-----IKLKVLDKPGPP---------------ASVKINKMYSDR 12907
Query: 567 SITGEPPPVA------TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
++ PP+ T D+ T+ ++ V +S +E E ++ I
Sbjct: 12908 AMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICA 12967
Query: 621 TNP--VGEDVASIFLQVVDVPDPP---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N VG+ V + + DPP + I+++ +D + W+PP DGG P+TGYL+
Sbjct: 12968 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLL 13027
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
E+++ + W K+N + E T ++T + EG YE RV A+N G +PS +K
Sbjct: 13028 EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARD 13087
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT-EPV 791
P P P V D T ++ +L W P G I GYLVE S+ WV N + +
Sbjct: 13088 PQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13147
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
++ F V L + FRV VN G S+P+ + ++I PP+ L LR+T I
Sbjct: 13148 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 13207
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEY 910
+ G + L VP +G+P P++ W+K L D + ++++DFDT + D+G+Y
Sbjct: 13208 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267
Query: 911 ELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ 970
L+++ K TI ++V++ GPP+NV VKE+ +A V W+ P DG S I+ Y VQ
Sbjct: 13268 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 13327
Query: 971 KADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKT 1030
K D + W V TS V++L G Y+FRV+ EN G+ D PG +++ + +T
Sbjct: 13328 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD-PGETRDAVKASQT 13386
Score = 246 bits (628), Expect = 9e-65
Identities = 155/494 (31%), Positives = 245/494 (49%), Gaps = 17/494 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
+E + P + LD S + + IVV AG +R+ ++G+PPP TW + T
Sbjct: 10016 IEMKDRLVSPDLQLDASVR---DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER---TLP 10069
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT- 648
IE SS VI++ QR +G Y++ N GE +I + V+DVP P +
Sbjct: 10070 QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAH 10129
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
++ + L W P DGG P+T Y++E+++ + W + + V T +I+G
Sbjct: 10130 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV-TRQNATVQGLIQGKA 10188
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFM----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y R+ A N+IG+ P + T + PI P L V++VT T TL W PP G
Sbjct: 10189 YFFRIAAENSIGMG-PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDG 10247
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I Y++E L G+E++ + + +TVK L G +RV VNI G+ +P+
Sbjct: 10248 GSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF 10307
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAP-LDT 883
+P+T ++ PP + L R +VGE L + GKP+P+V W K A L+
Sbjct: 10308 CTKPITCKDELAPPTLHL--DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLED 10365
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVK 942
R H++T+ +A RSDSG+Y + V+ ++ VV++ GPP+ V
Sbjct: 10366 DRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFD 10425
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
EV ++ W+ P DDG S+I Y ++K + W V + T+C VS L+ G +Y
Sbjct: 10426 EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 10485
Query: 1003 YFRVYTENICGLSD 1016
FR++ EN+ G+SD
Sbjct: 10486 IFRIHAENLYGISD 10499
Score = 246 bits (627), Expect = 1e-64
Identities = 150/488 (30%), Positives = 235/488 (48%), Gaps = 9/488 (1%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
++E V + E P + L + + + AG LRL VS++G PPPV TW K
Sbjct: 22937 EIEPVERIEIPDLEL---ADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQG---IDL 22990
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
R I+ S +++ R D G+YTI+ N G+ A++ ++V D P P +V++
Sbjct: 22991 ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVK 23050
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V D + WE P DGG PV Y+VE K++ + R K ++T Y + ++EG +
Sbjct: 23051 EVSRDSVTITWEIPTIDGGAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTM 23109
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y RV N G+ +P + + P L V DVT +T TL W P G +
Sbjct: 23110 YYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRL 23169
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
GY++E C G+E W+ T TV +L G + LFR+ N G SEP
Sbjct: 23170 TGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 23229
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVH 887
VT++++ P I L ++T G + LV+P G+P P W G+ L ++ RV
Sbjct: 23230 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 23289
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWG 946
V T +R+ D+GEY L ++ + TI++ +++K GPP + + E+
Sbjct: 23290 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 23349
Query: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRV 1006
T+ + W+ P+ DG + + GY V++ D W V E ++ + L GNEY FRV
Sbjct: 23350 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 23409
Query: 1007 YTENICGL 1014
N G+
Sbjct: 23410 AATNRFGI 23417
Score = 243 bits (620), Expect = 8e-64
Identities = 162/502 (32%), Positives = 240/502 (47%), Gaps = 27/502 (5%)
Query: 527 EIKVEYVPKQ--EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEV 584
E+K PK+ EPP+I LD S + ++V AG +RL + G P P TW K
Sbjct: 12093 ELKEAIKPKEILEPPEIDLDASMR---KLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID 12149
Query: 585 FTTTEGRTRIEKRVDCSSF-VIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
+G+ + VD +F VI ++ R+D G+Y++ + NP GE + ++V+D P P
Sbjct: 12150 NVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVS 12206
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++++ V + + W PP DGG VT Y+VE+++ + W + EV +T++ T +
Sbjct: 12207 DLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNL 12265
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSE---PLHLIVEDVTDTTTTLKWRPP 760
+ G Y RV AVN G P+ KP + P SE P L V ++T + TL W PP
Sbjct: 12266 VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPP 12325
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANT----EPVERCGFTVKNLPTGARILFRVVGVNI 816
R G IDGY+ Y EE PA+ V+ V L G + FRV N
Sbjct: 12326 LRDGGAKIDGYITSY----REEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNA 12381
Query: 817 AGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P +E PPKI +P + K G++L + GKP P W K
Sbjct: 12382 VGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKK 12437
Query: 877 GGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G + T S + V +D ++ ++ R DSG Y L+ + + DT I++ V++ GP
Sbjct: 12438 GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGP 12497
Query: 936 PINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + ++ + W P +DG S I Y V+K D +W TSC V
Sbjct: 12498 PQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVG 12557
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
LI G EY FRV EN G+S+
Sbjct: 12558 KLIPGQEYIFRVRAENRFGISE 12579
Score = 239 bits (610), Expect = 1e-62
Identities = 152/487 (31%), Positives = 236/487 (48%), Gaps = 22/487 (4%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
K E P I LD + N + AG LRL V I G P P W K D G R
Sbjct: 16439 KLEAPDIDLDLELRKIIN---IRAGGSLRLFVPIKGRPTPEVKWGKVD-------GEIRD 16488
Query: 595 EKRVDCSS----FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSV 650
+D +S V+++ R D G+YT+ + N G A + ++V+D P PP +++T +
Sbjct: 16489 AAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEI 16548
Query: 651 GEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYE 710
+D + WEPP+ DGG + Y+VE+++ + + + + +++ ++ EG Y
Sbjct: 16549 TKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCH-KNSWKIDQLQEGCSYY 16607
Query: 711 MRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDG 770
RV A N G+ P+ P P + V+DVT + +L W P G I
Sbjct: 16608 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 16667
Query: 771 YLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
Y+VE + SE+W + V+ + NL G LFRVV VN GRS+P +LA P+
Sbjct: 16668 YIVEMQAKHSEKW--SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIV 16725
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVR 889
+++ P + + +Y +VG+ L + VP G+P+P + WTK G PL T+R++V
Sbjct: 16726 AKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 16782
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTN 948
S T +++ + D G+Y ++V + TA+I I ++K PP V +V +
Sbjct: 16783 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES 16842
Query: 949 ALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYT 1008
+ W P G +I Y VQK D T W V T+ V+ L G EY FR++
Sbjct: 16843 ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFA 16902
Query: 1009 ENICGLS 1015
EN G S
Sbjct: 16903 ENRYGQS 16909
Score = 238 bits (607), Expect = 2e-62
Identities = 178/616 (28%), Positives = 277/616 (44%), Gaps = 39/616 (6%)
Query: 429 EAELIVEEKQLEVLQDIA---DLTVKASEQAVFKCEVSDEK-VTGKWYKNGVEVRPSKRI 484
EAE + E K+ + I +T+KA ++ + V + T KW K EV S +
Sbjct: 12389 EAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHL 12448
Query: 485 TISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLD 544
+ L+I DV +D G Y+ + S+ + +IKV + PP+ D
Sbjct: 12449 AVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKVVVMDAPGPPQPPFD 12503
Query: 545 CSGKTSENA-----IVVVAGNKLRLDVSITGEPPPVATWLKGDEVF---TTTEGRTRIEK 596
S ++ I + G +IT +GD V + T+ R+ K
Sbjct: 12504 ISDIDADACSLSWHIPLEDGGS-----NITNYIVEKCDVSRGDWVTALASVTKTSCRVGK 12558
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ E R+ I + VA VP P+ R+T V +D
Sbjct: 12559 LIPGQEYIFRVRA---ENRFGISEPLTSPKMVAQF---PFGVPSEPKNARVTKVNKDCIF 12612
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
+ W+ P DGG P+ GYL+ERK++ S W+K N + T Y ++EG+ Y R++A+
Sbjct: 12613 VAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 12672
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G S PS T+ P P V DVT +T +L W P G I GY VE C
Sbjct: 12673 NKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC 12732
Query: 777 LEGSEEWVPANTEP--VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
++WV NT P + + +T L A+ FR + S P+ + PVTI
Sbjct: 12733 KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE 12792
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA---PLDTSRVHVRTS 891
PP+I L ++ K G + L GKP P V W K G P + ++ ++ +
Sbjct: 12793 NVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN 12852
Query: 892 DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALV 951
F R DSG+Y ++ + + +ATI+++V++K GPP +V + +++ A++
Sbjct: 12853 LCTLELF--SVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAML 12910
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P +DG SEI Y V K + W V TSC+V LI G+EY FR+ EN
Sbjct: 12911 SWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENK 12970
Query: 1012 CGLSD----SPGVSKN 1023
G+ D P ++KN
Sbjct: 12971 YGVGDPVFTEPAIAKN 12986
Score = 238 bits (606), Expect = 3e-62
Identities = 157/496 (31%), Positives = 232/496 (46%), Gaps = 19/496 (3%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
EPP++ LD + ++ + G+ LRL I G P P TW K D T + RI+
Sbjct: 10717 EPPELILDANMAREQH---IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT---KARIDV 10770
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
S I +A ED G Y++ V NP G S+ + V+D P PP + ++ + +D
Sbjct: 10771 TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10830
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W+ P+ DGG +T Y+VER+ S +W L+ + ++ + + EG Y RV A
Sbjct: 10831 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAE 10889
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G KP P+ P P L DV T +L W P+R G I GYLV
Sbjct: 10890 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 10949
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
EY EG+++W+ T C V L G FRV NI G P T P+ +E
Sbjct: 10950 EYQEEGTQDWIKFKTVTNLEC--VVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 11006
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH-VRTSD 892
PP + L L + + K G + +G P P WT G+ + T + V T +
Sbjct: 11007 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11066
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALV 951
F +V ++ R D+GEY+++V T + + V++ GPP + + +V + +
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11126
Query: 952 EWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
WQ PKDDG S ++ Y V+K D + W V + T + L G EY FRV EN
Sbjct: 11127 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 11186
Query: 1012 CG----LSDSPGVSKN 1023
G L +P V+K+
Sbjct: 11187 IGVGPPLDSTPTVAKH 11202
Score = 234 bits (598), Expect = 3e-61
Identities = 149/496 (30%), Positives = 239/496 (48%), Gaps = 18/496 (3%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
VE V ++ P LD + + +VV AG +R+ V I G P P TW K + +
Sbjct: 14268 VEIVEREMAPDFELDAELRRT---LVVRAGLSIRIFVPIKGRPAPEVTWTKDN---INLK 14321
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
R IE + +I R D G++ + + NP G+ + ++V+D P P +R T
Sbjct: 14322 NRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTD 14381
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ +D L W+ P+ DGG +T Y+VE+++ + + + + TY+ T + EG Y
Sbjct: 14382 ITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH-KCTYKVTGLSEGCEY 14440
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
RV A N G+ +P+ T+P S P L + D+T +T +L W P G I
Sbjct: 14441 FFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKIT 14500
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
GY++E +GS++W T C V+NL G F+V+ VN AGRS P ++PV
Sbjct: 14501 GYVIEAQRKGSDQWTHITTVKGLEC--VVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPV 14557
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHV 888
++E P++ L ++ I K G+ + + +P G+P+P V W KG L T RV+
Sbjct: 14558 IVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNF 14617
Query: 889 RTSDFDTVFFVRQAARSDSGEYELSVQ--IENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
T+ T+ + + RSDSG Y L+ + + + D TI++ + GPP + EV
Sbjct: 14618 ETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI--PGPPTGPIKFDEVS 14675
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
W P++DG I Y V+ + W + T+ + L G EY FR
Sbjct: 14676 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 14735
Query: 1006 VYTENICGLSDSPGVS 1021
V +N G+ PG++
Sbjct: 14736 VKAQNRYGV--GPGIT 14749
Score = 232 bits (592), Expect = 1e-60
Identities = 161/551 (29%), Positives = 248/551 (45%), Gaps = 28/551 (5%)
Query: 469 GKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
G W+K E R T++ + G +K + + +GD V
Sbjct: 21801 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG------------- 21847
Query: 527 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 586
++ V + P++ +D + K + VV AG +RL ++ G P P A W K D +
Sbjct: 21848 --TIKAVDRLTAPELDIDANFKQTH---VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 21902
Query: 587 TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVR 646
R I S+ +E+ R D G+YT+ V N G + ++V+D P PP +
Sbjct: 21903 L---RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPIT 21959
Query: 647 ITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEG 706
V A L+W+ P+ DGG + Y+VE+++ + W ++ E T ++ + EG
Sbjct: 21960 FKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDLAEG 22018
Query: 707 ILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAG 766
+ Y RV AVN GV +P +P + + P L V D + ++ L W P+ G
Sbjct: 22019 VPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGS 22078
Query: 767 GIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA 826
I GYL+E +GS+ WV A ++ FTV+ L FRV N AG SEP
Sbjct: 22079 RITGYLLEMRQKGSDFWVEAG--HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAF 22136
Query: 827 QPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSR 885
V I+E P L Q K G + VP G+P P+V W L +T R
Sbjct: 22137 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDR 22196
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
V + T+ T V+ + R DSG Y L+++ T ++ + V+ + GP + V V
Sbjct: 22197 VSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV 22256
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
+ ++ W PKD G +EI Y V+K + T W V + T V+ L EY F
Sbjct: 22257 SAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSF 22316
Query: 1005 RVYTENICGLS 1015
RV +EN G+S
Sbjct: 22317 RVSSENRFGVS 22327
Score = 231 bits (588), Expect = 4e-60
Identities = 141/480 (29%), Positives = 230/480 (47%), Gaps = 7/480 (1%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ + V+ N + + V TG P P ATW GD+V T + R +++ + VI ++R
Sbjct: 6904 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD-RVKMKTLSAYAELVISPSER 6962
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
D+G YT+K+ N V I + V+ P P+ ++ + +D L WEPP DGG P+
Sbjct: 6963 SDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7022
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
TGY+VE+++ + W K+ + T+ + +++G Y +V A N G +P+ +P
Sbjct: 7023 TGYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEP 7081
Query: 731 FMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPAN 787
P + P ++ D T + L W PP G I GY+VE C GS++WV
Sbjct: 7082 VNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 7141
Query: 788 TEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
EPV V L G +RV +N G S+P+ + + + E P+I L L
Sbjct: 7142 -EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLL 7200
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSD 906
K G ++ L GKP P++ WTK L R+ + + + + RSD
Sbjct: 7201 AGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSD 7260
Query: 907 SGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966
+G Y + + TA + + V++K GPP + +V + L+ W P+DDG S+I
Sbjct: 7261 TGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7320
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y V++ + W + + T+ + LI EY FRV EN+ G+ + S TA+
Sbjct: 7321 YVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAK 7380
Score = 228 bits (581), Expect = 3e-59
Identities = 138/484 (28%), Positives = 226/484 (46%), Gaps = 11/484 (2%)
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
++E P +D + + ++V AG + V G P P W K D T R +
Sbjct: 19683 REEEPLFDIDSEMRKT---LIVKAGASFTMTVPFRGRPVPNVLWSKPD---TDLRTRAYV 19736
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ +S IE+A R D G+YT+ + N + ++ ++V+D P PP + + V ++
Sbjct: 19737 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKES 19796
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A+L W+ P DGG PV Y +E+++ + W+ + +Y+ T + EG +Y RV
Sbjct: 19797 AVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKVTNLQEGAIYYFRVS 19855
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N GV P+ + S P L V ++ + +L W P G I Y+VE
Sbjct: 19856 GENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVE 19915
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+G + WV + V L + FRV N AG S+P L PV I+E
Sbjct: 19916 ALEKGQKNWVKCAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQ 19973
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDF 893
EPP+I + T + G L + +P GKP P+V ++ G PL T R + +
Sbjct: 19974 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20033
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+ ++++ +D+G YE++ + A I I V+++ GPP V++ ++ + ++
Sbjct: 20034 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLK 20093
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W+ PK DG S++ Y + K + T W V T V L G EY FR+ EN
Sbjct: 20094 WEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRF 20153
Query: 1013 GLSD 1016
G+SD
Sbjct: 20154 GISD 20157
Score = 226 bits (577), Expect = 7e-59
Identities = 133/383 (34%), Positives = 202/383 (52%), Gaps = 10/383 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE-VFTET 696
VPD P+ +T V +D A++ W P +DGGKP+T Y++E+++ S+RW ++ + + T
Sbjct: 10514 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 10572
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTT 753
+ ++EG YE RV A N IG+ PS +KP PIA S P++ D T +
Sbjct: 10573 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10632
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT---VKNLPTGARILFR 810
L W+PP G I GY+VEY G EEW AN P E C T V L G FR
Sbjct: 10633 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTP-ESCPETKYKVTGLRDGQTYKFR 10691
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V+ VN AG S+PA + +PV +++ EPP++ L ++ + KVG+ L L +G P P
Sbjct: 10692 VLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFP 10751
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
+V W K T + + + + +R AA D G Y L+V+ T ++++ V+
Sbjct: 10752 KVTWKKEDRDAPT-KARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVL 10810
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTS 990
+K GPP ++ V E+ + + W+ P DDG S I Y V++ D + +W + ++ S
Sbjct: 10811 DKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKS 10870
Query: 991 CTVSDLIVGNEYYFRVYTENICG 1013
L GN+Y FRV EN G
Sbjct: 10871 HFAKHLNEGNQYLFRVAAENQYG 10893
Score = 225 bits (574), Expect = 2e-58
Identities = 147/490 (30%), Positives = 230/490 (46%), Gaps = 22/490 (4%)
Query: 534 PKQE----PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK--GDEVFTT 587
PK E PP+I LD + + + A LRL V I G P P W + G+ +
Sbjct: 15352 PKAEDRMLPPEIELDADLR---KVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--- 15405
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ IE + ++ + R D G+Y + V N G A + ++V+D P PP+ +++
Sbjct: 15406 --DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKV 15463
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
V + L W+PP+ DGG + Y+VE+++ + + + +T+++ ++ EG
Sbjct: 15464 KEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCH-KTSWKVDQLQEGC 15522
Query: 708 LYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
Y RV A N G+ P+ + P + + DVT + +L W P G
Sbjct: 15523 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSR 15582
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
I GY+VE +GS++W T V T+ L G FRV N G S+P L+
Sbjct: 15583 ILGYIVEMQTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSV 15640
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRV 886
PV +++ PP +L L T+ GE L + VPF G+P P V W K PL T+RV
Sbjct: 15641 PVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRV 15697
Query: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVW 945
+ +++ +++ ++ A R D G Y + + + T+ + V++K GPP V + EV
Sbjct: 15698 NAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT 15757
Query: 946 GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFR 1005
+ + W PK DG S I Y V+K D T W V T+ L G EY FR
Sbjct: 15758 ADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15817
Query: 1006 VYTENICGLS 1015
+ EN G S
Sbjct: 15818 IAAENRYGKS 15827
Score = 219 bits (557), Expect = 2e-56
Identities = 145/484 (29%), Positives = 237/484 (48%), Gaps = 18/484 (3%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE-K 596
PP+ LD + + +++ AG +RL V + G PPP TW K + R ++ K
Sbjct: 13193 PPEGELDADLRKT---LILRAGVTMRLYVPVKGRPPPKITWSKPN---VNLRDRIGLDIK 13246
Query: 597 RVDCSSFV-IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
D +F+ E+ + D G+Y + + N G+ +I ++V+D P PP V + + +D A
Sbjct: 13247 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSA 13306
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WEPP+ DGG P+ Y+V+++ + W + E ++T++ + EG Y RVFA
Sbjct: 13307 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFA 13365
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPL-HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
N G+ P T+ + + T P+ L V V+ ++ ++ W+ P+ G I GY+V+
Sbjct: 13366 ENEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD 13424
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
+ E ++ + ++ ++ K+L G FRV N G P+ + V R+
Sbjct: 13425 FLTEENKWQRVMKSLSLQ---YSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDD 13479
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDT-SRVHVRTSDF 893
P + L Y+ K L +P +GKP P V W KG PL T +RV V +S
Sbjct: 13480 VVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAV 13539
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVE 952
+T V +SD+G+Y ++++ TI I+VV K G P + EV ++
Sbjct: 13540 NTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLK 13599
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W PKDDG SEI Y ++K D +W + T+ V+ L G EY FRV EN
Sbjct: 13600 WAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKY 13659
Query: 1013 GLSD 1016
G+ +
Sbjct: 13660 GVGE 13663
Score = 218 bits (556), Expect = 2e-56
Identities = 158/516 (30%), Positives = 233/516 (45%), Gaps = 54/516 (10%)
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+++ V QE P+I LD + V AG K+ L ++TG+P P TW K D +
Sbjct: 7181 EIQAVDTQEAPEIFLDVKLLAG---LTVKAGTKIELPATVTGKPEPKITWTKADMILKQD 7237
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
+ R IE S+ I ++R D G Y I+ N G A + + V+D P PP A IT
Sbjct: 7238 K-RITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDIT 7296
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
V + +L W PP DGG +T Y+VER+ S+ W KL+ V +T +++TK+I
Sbjct: 7297 DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKLIPNKE 7355
Query: 709 YEMRVFAVNAIGVSQPSMNTKPF---MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGA 765
Y RV A N GV +P + P P P L D+T TL W P+ G
Sbjct: 7356 YIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7414
Query: 766 GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATL 825
I GY VE +++WV N PV+ + VK L + FRV+ N+AG +P+
Sbjct: 7415 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7474
Query: 826 AQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPL 881
+P+ I++ +PP V GK ++ WTK GGA +
Sbjct: 7475 TEPILIKDPIDPP----------------WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKI 7518
Query: 882 DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG------- 934
++ + + + D +VR A + ++ L +E + + R+R V KAG
Sbjct: 7519 ESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQE--YSFRVRAVNKAGESEPSEP 7574
Query: 935 --------------PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF 980
PP + V + A ++W P+ DG S I Y V+K D + W
Sbjct: 7575 SDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQ 7634
Query: 981 NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T CTV+ L G+ Y FRV EN G SD
Sbjct: 7635 TVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7670
Score = 218 bits (556), Expect = 2e-56
Identities = 180/670 (26%), Positives = 295/670 (44%), Gaps = 50/670 (7%)
Query: 364 EMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVIT 423
E VE +G Q W G+ T E + ++ +L F + ++G +T
Sbjct: 20999 EYVVERKGKGEQT-WSHAGISKTCE------IEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21051
Query: 424 NGGQCEAELIVEEKQLEVLQDI--ADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRP 480
G ELI+ + L DI A +TV+ + + K + W K+G+ ++
Sbjct: 21052 IGPITVKELIITPEV--DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21109
Query: 481 SKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPK 540
S+ + S L I + + E G YT + D ++ + + + PK
Sbjct: 21110 SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGP--- 21166
Query: 541 IHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGR--TRIEKRV 598
+ ++++ D I P G+ + E R ++ ++
Sbjct: 21167 ----------------IRFDEIKADSVILSWDVPEDNG-GGEITCYSIEKRETSQTNWKM 21209
Query: 599 DCSS-----FVIESAQREDEGRYTIKVTNPVGED---VASIFL--QVVDVPDPPEAVRIT 648
CSS F + + ++ E ++ ++ N G V+SI + +P PP I
Sbjct: 21210 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIY 21269
Query: 649 SVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL 708
+V D L W+ P+YDGG VTG+ VE+K++ S W K+N + Y +T ++EG+
Sbjct: 21270 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 21329
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
Y+ RV+A N+ G+S PS +K + ++P P DVT T TLKW PP R G I
Sbjct: 21330 YQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKI 21389
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQ 827
GY +E +G+E WV N V C +TV L G R FR++ N G S P+ +
Sbjct: 21390 VGYSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSG 21448
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH 887
+ R+ PP + I K GE L + QG+P P+V W K G ++ R++
Sbjct: 21449 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMN 21507
Query: 888 VRTSDF--DTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEV 944
+ +D T FVR A R G Y + + + A I+++V + G + + +
Sbjct: 21508 MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNI 21567
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
G + W AP +DG + I Y ++K + + W + ++ S T LI GNEY F
Sbjct: 21568 TGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQF 21627
Query: 1005 RVYTENICGL 1014
RV N G+
Sbjct: 21628 RVSAVNKFGV 21637
Score = 218 bits (555), Expect = 3e-56
Identities = 160/568 (28%), Positives = 254/568 (44%), Gaps = 31/568 (5%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W+K+ V ++ + R+ L I D ED G Y L+ SA + V
Sbjct: 15684 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVV-----KLTNSAGEAIETLNV 15738
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITG-----EPPPVATWLKGDEVF 585
+ K PP + T+++ + K SI TW ++
Sbjct: 15739 IVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW----QIV 15794
Query: 586 TTTEGRTRIEK---RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+ T RT I+ + C + A G+ T + P ++ VP PP
Sbjct: 15795 SATVARTTIKACRLKTGCE-YQFRIAAENRYGKSTYLNSEP------TVAQYPFKVPGPP 15847
Query: 643 EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTK 702
+T D + W P+ DGG V GY +ERK++ S W+KLN +T +++T
Sbjct: 15848 GTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTG 15907
Query: 703 MIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNR 762
+ EG+ YE RV A N +G+ +PS ++ ++ P P VT + TL+W+ P
Sbjct: 15908 LEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTY 15967
Query: 763 IGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSE 821
G I GY+VE W+ A+ + F V L R FRV+ N AG SE
Sbjct: 15968 DGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 16027
Query: 822 PATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL 881
P+ +T R+ +PP+I + + T + GE + GKP P + W KG L
Sbjct: 16028 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16087
Query: 882 -DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-V 939
+T+R+ ++++DF T V+ A R DSG Y L + + + T+ ++V+++ GPP V
Sbjct: 16088 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPV 16147
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVG 999
++ V + W+ P DG S+I+ Y V++ + + W V + SC V+ L+ G
Sbjct: 16148 VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG 16207
Query: 1000 NEYYFRVYTENICG----LSDSPGVSKN 1023
NEY FR+ N G L P V+KN
Sbjct: 16208 NEYTFRIMAVNKYGVGEPLESEPVVAKN 16235
Score = 218 bits (554), Expect = 3e-56
Identities = 167/650 (25%), Positives = 284/650 (43%), Gaps = 55/650 (8%)
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRIT 485
+C+ +L+ +L+V + I L VKA F + V T KW +G E++ + T
Sbjct: 11003 ECQEKLVPPSVELDV-KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11061
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDC 545
+ L I + D G+Y A S + ++ + V PP ++
Sbjct: 11062 VETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP-----GPPTGPINI 11116
Query: 546 SGKTSENAIVVVAGNKLRLDVSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVD 599
T E+ ++I+ +PP PV ++ ++ T + +
Sbjct: 11117 LDVTPEH-------------MTISWQPPKDDGGSPVINYIV-EKQDTRKDTWGVVSSGSS 11162
Query: 600 CSSFVIESAQREDEGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ I Q+ E + ++ N +G + ++ P PP +T + E+
Sbjct: 11163 KTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENA 11222
Query: 655 AILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVF 714
A + W P DGG P+TGY +ER++ + +W+++N + + T + EG YE RVF
Sbjct: 11223 ATVSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVF 11281
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G+S+PS ++ P PI P P++ ++D + T L W P G I GY
Sbjct: 11282 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 11341
Query: 772 LVEYCLEGSEEWVPANT-EPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
+VE G+ +W N E + +C F V L G FR+ NI G EP LA+ V
Sbjct: 11342 VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVI 11401
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRT 890
++I PP++ L R +VG+ + ++ +G+P P + WTK G L +
Sbjct: 11402 AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI 11461
Query: 891 SDFDTV-FFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
D V +++A R+D G+Y +S + + + + V+++ GP N+ V V N
Sbjct: 11462 QDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENC 11521
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W+ P D+G SEI + V+ W ++ + ++L+ NEYYFRV E
Sbjct: 11522 TISWENPLDNGGSEITNFIVEYRKPNQKGW-SIVASDVTKRLIKANLLANNEYYFRVCAE 11580
Query: 1010 NICGLS---------------DSPGVSKNTARILKTGITFKPFEYKEHDF 1044
N G+ D PG +N I G TF +++ D+
Sbjct: 11581 NKVGVGPTIETKTPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDY 11629
Score = 217 bits (553), Expect = 4e-56
Identities = 125/382 (32%), Positives = 192/382 (50%), Gaps = 3/382 (0%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP PP ++T+V +D + W P+ DGG P+ GY VERK++ W ++ +
Sbjct: 14761 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 14820
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKW 757
++S+ + +GI YE RV A N G S+PS ++P + + P P + ++T T TLKW
Sbjct: 14821 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKW 14880
Query: 758 RPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIA 817
P G I Y+VE + W+ AN + FTV L A FRV+ N A
Sbjct: 14881 AKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAA 14940
Query: 818 GR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
G S P+ + +T R+ E PKI++ + T I K GE L G+P P + W+K
Sbjct: 14941 GAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSK 15000
Query: 877 GGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
G L+ T+++ ++ +DF T + + R DSG Y L+ ++V+++ GP
Sbjct: 15001 DGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP 15060
Query: 936 PIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVS 994
P + V EV ++ W P DDG ++I Y VQK + + W NV + T V+
Sbjct: 15061 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVT 15120
Query: 995 DLIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 15121 KLLKGNEYIFRVMAVNKYGVGE 15142
Score = 217 bits (552), Expect = 6e-56
Identities = 155/560 (27%), Positives = 257/560 (45%), Gaps = 34/560 (6%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
E P+I LD + +TS ++ AG +++ + G PPP TW K DE ++ R IE
Sbjct: 20770 EAPEIDLDVALRTS---VIAKAGEDVQVLIPFKGRPPPTVTWRK-DEKNLGSDARYSIEN 20825
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVAS-IFLQVVDVPDPPEAVRITSVGEDWA 655
S I R D G+Y + + N VGE +S + ++V+D P + +++ V
Sbjct: 20826 TDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV 20885
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L+W+PP+ DGG P+ Y++E++ + W ++ + + T+++ + E + RV A
Sbjct: 20886 TLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLA 20944
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY 775
N IG+ +P T+P + L ++D T T+ L W P+ G I Y+VE
Sbjct: 20945 ENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 21004
Query: 776 CLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIA 835
+G + W A + C V L + + FRV N G S+P T+ P+T++E+
Sbjct: 21005 KGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELI 21061
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFD 894
P++ L ++G ++L +P++GKP+P + W K G PL S V ++
Sbjct: 21062 ITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK 21121
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV---VEKAGPPIN----VMVKEVWGT 947
++ A + G+Y + + D A RI V V GPP + E+
Sbjct: 21122 ITLSIKNAKKEHGGKYTV------ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKAD 21175
Query: 948 NALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVY 1007
+ ++ W P+D+G EI Y ++K + W V T+ V +L+ EY FRV
Sbjct: 21176 SVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVR 21235
Query: 1008 TENICGLS----DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGY 1063
EN G+S S V+K+ RI G KP Y M+ + P+ D G
Sbjct: 21236 AENRYGVSQPLVSSIIVAKHQFRI--PGPPGKPVIYNVTSDGMSLTWDAPVYD-----GG 21288
Query: 1064 SAALNCAVRGHPKPKVVWMK 1083
S V + ++W K
Sbjct: 21289 SEVTGFHVEKKERNSILWQK 21308
Score = 216 bits (551), Expect = 8e-56
Identities = 174/617 (28%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 434 VEEKQLEVLQDIADLTV-KASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR 491
VE +++V D + KA E + +VS T +W K+G E+ + ++ I
Sbjct: 14959 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15018
Query: 492 FHKLVIDDVRPEDEGDYTFV---PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
LV D D G YT P G+A + V+ + + PP+ L +
Sbjct: 15019 STNLVNKDSTRRDSGAYTLTATNPGGFAKHI--------FNVKVLDRPGPPEGPLAVTEV 15070
Query: 549 TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF-----TTTEGRTRIEKRVDCSSF 603
TSE + ++ PP K D T+ T + V +
Sbjct: 15071 TSEKCV-------------LSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 15117
Query: 604 VIESAQREDEGRYTIKVTNP--VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILV 658
+ + +E + + N VGE + S + V+ PDPP+ +T++ +D ++
Sbjct: 15118 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVC 15177
Query: 659 WEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
W P DGG + Y+VER+ K QRW+K N + T+ Y+ + + EG YE R+ A NA
Sbjct: 15178 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENA 15237
Query: 719 IGVSQPSMNTKPFMPIAPT----SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
G+S PS T PF T P + V D + ++ ++ W P G I GY+VE
Sbjct: 15238 AGISAPS-PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVE 15296
Query: 775 YCLEGSEEW-VPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
L +EW + ++ +T+ L R+ +N G EPA + +
Sbjct: 15297 IALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAED 15356
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKG-GAPLDTSRVHVRTSD 892
PP+I L LR+ + L L VP +G+P P+V W + G LD + + TS
Sbjct: 15357 RMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIE-STSS 15415
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVE 952
+ T+ V R DSG+Y L+V+ + +A + +RV++ GPP ++ VKEV T+ +
Sbjct: 15416 Y-TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLT 15474
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENIC 1012
W P DG S+I Y V+K + + V TS V L G YYFRV EN
Sbjct: 15475 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEY 15534
Query: 1013 GLSDSPGVSKNTARILK 1029
G+ G+ TA +K
Sbjct: 15535 GI----GLPAETAESVK 15547
Score = 215 bits (548), Expect = 2e-55
Identities = 150/495 (30%), Positives = 223/495 (45%), Gaps = 24/495 (4%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
QEPP + LD S K I ++AG LR+ +TG P P W K E + R I+
Sbjct: 8602 QEPPAVELDVSVK---GGIQIMAGKTLRIPAVVTGRPVPTKVWTK--EEGELDKDRVVID 8656
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S +I+ A R+D GRY I TN G A+ ++V DVP P ++
Sbjct: 8657 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8716
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYESTKMIEGILYEMRVF 714
+L W P DGG +TG+++ERK W + + TE + + T ++EG Y+ RV
Sbjct: 8717 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ---PIETERSKCDITGLLEGQEYKFRVI 8773
Query: 715 AVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
A N G P + P + P+ P + P L + T +T TL W+ P G I GY
Sbjct: 8774 AKNKFGCG-PPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGY 8832
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
++E ++ N F V+NL FRV VN G SEP +L V I
Sbjct: 8833 IIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-SLPLNVVI 8891
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGA-------PLDT 883
++ PP I+L +R I+ K GE +++ G P P++ W+K L
Sbjct: 8892 QDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQI 8951
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKE 943
++ V S+ T + +A R D G Y ++ + + V ++ PP N+ V +
Sbjct: 8952 TKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9011
Query: 944 VWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIVGNE 1001
+ + + W AP D+G SEI Y + K D +K EW V + LI +
Sbjct: 9012 IKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQ 9071
Query: 1002 YYFRVYTENICGLSD 1016
Y FRV N G+SD
Sbjct: 9072 YEFRVRAVNKYGISD 9086
Score = 213 bits (543), Expect = 6e-55
Identities = 157/584 (26%), Positives = 263/584 (45%), Gaps = 34/584 (5%)
Query: 448 LTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
L +K+ E K V V W+K+GVE+ + I+ V L + D + G
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRL-- 564
YT + S A++ ++KV+ P + I + G K+ L
Sbjct: 21531 VYTVEAKNASGSAKAEI---KVKVQDTPGKVVGPIRF-----------TNITGEKMTLWW 21576
Query: 565 DVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN-- 622
D + P+ ++ ++ T+ IE + + S+ +E ++ + N
Sbjct: 21577 DAPLNDGCAPITHYII-EKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKF 21635
Query: 623 ----PVGED--VASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
P+ D VA I V D P PE IT + L W P DGG + Y++E
Sbjct: 21636 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITG---NSITLTWARPESDGGSEIQQYILE 21692
Query: 677 RKKKGSQRWMK-LNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--- 732
R++K S RW+K ++ +ET ++ T + EG YE V A NA GV S ++
Sbjct: 21693 RREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE 21752
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
P+ P P + V D + TT +L+W P G I GY++E C +W N E
Sbjct: 21753 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV 21812
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
+ +TV +L G FRV +N AG+ + + + + P++ + + +QT++
Sbjct: 21813 KTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVV 21872
Query: 853 KVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ G + L + +QG+P P VW+K + L + R + T+D + V R+D+G+Y L
Sbjct: 21873 RAGASIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTL 21931
Query: 913 SVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKA 972
+V+ + + T ++V++ GPP + K+V +A + W AP DG + I Y V+K
Sbjct: 21932 TVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKR 21991
Query: 973 DKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + E+ V+DL G YYFRV N G+ +
Sbjct: 21992 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 22035
Score = 213 bits (542), Expect = 8e-55
Identities = 131/391 (33%), Positives = 192/391 (49%), Gaps = 16/391 (4%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PDPPE +T V ++ +VW PP YDGGK +TGY +E+K+K S RW+ +N E
Sbjct: 11902 PDPPE---VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 11958
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
+ ++ Y+ RV A N IG+ +PS+ ++P + PI P P + V D T + TL
Sbjct: 11959 KVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITL 12018
Query: 756 KWRPPNRIGAGGIDGYLVEY-----CLEGSEEWVPAN-TEPVERCGFTVKNLPTGARILF 809
W P G I GY+VE E W N + R FTV +L F
Sbjct: 12019 GWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEF 12078
Query: 810 RVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPR 869
RV N G PA L + + +EI EPP+I L +R+ I + G + L +G+P
Sbjct: 12079 RVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPA 12138
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRV 929
P+V W K G + V D + + R DSG+Y L++ + + +RV
Sbjct: 12139 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 12198
Query: 930 VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
++ GP ++ V +V T+ V W P++DG S++ Y V+K + W V + T
Sbjct: 12199 LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKT 12258
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGV 1020
S V++L+ GNEYYFRV N G PGV
Sbjct: 12259 SFHVTNLVPGNEYYFRVTAVNEYG----PGV 12285
Score = 211 bits (538), Expect = 2e-54
Identities = 145/521 (27%), Positives = 236/521 (45%), Gaps = 40/521 (7%)
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW--------LKGDEVFTT 587
QE P++ +D +++ +V AG+++R+ I G P P ++W D V
Sbjct: 9308 QEEPEVFIDIG---AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDI 9364
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
E ++E + S +I +R G+Y+I N G+ A+ ++V+DVP PP+ +++
Sbjct: 9365 PED-AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKV 9423
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
+ + L W+ P DGG + GY++E++ + W K+N + TT+ ++
Sbjct: 9424 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDC-GSTTFVVPDLLSEQ 9482
Query: 708 LYEMRVFAVNAIGVSQP---SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y RV A N G+ P T PI P P+ L + +T T L W+PP G
Sbjct: 9483 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDG 9542
Query: 765 AGGIDGYLVEYCL------EGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG 818
+ Y+VE CL E W N VE FTV++L G FRV VN AG
Sbjct: 9543 GSPVTHYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAG 9601
Query: 819 RSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
S+P+ P + PP I L + + G +N+V +G P P + W K
Sbjct: 9602 VSKPSATVGPCDCQRPDMPPSIDLKEFMEV----EEGTNVNIVAKIKGVPFPTLTWFK-- 9655
Query: 879 AP----------LDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
AP L + V+ D + Q+ RSD+G Y ++ + +R+
Sbjct: 9656 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9715
Query: 929 VVEKAGPPIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR 987
V+ + GPP+ + + V + W PKDDG S+I Y ++K + W +V +
Sbjct: 9716 VLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPK 9775
Query: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
+ T+ L+ G+EY FR+ +N G+ + TAR L
Sbjct: 9776 ECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNL 9816
Score = 211 bits (536), Expect = 4e-54
Identities = 160/614 (26%), Positives = 270/614 (43%), Gaps = 45/614 (7%)
Query: 431 ELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHV 489
+L++E +V + +V+ + + +S K T W K+G+ ++ + RI ++
Sbjct: 16728 DLVIEP---DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDS 16784
Query: 490 GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
L I + +D G Y G ++ I++ + K +PPK + +
Sbjct: 16785 LDLTTLSIKETHKDDGGQY-----GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVS 16839
Query: 550 SENAIV-----VVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 604
+E+ + + G + + W +V + T RT ++
Sbjct: 16840 AESITLSWNPPLYTGGCQITNYIVQKRDTTTTVW----DVVSATVARTTLK--------- 16886
Query: 605 IESAQREDEGRYTIKVTNPVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVW 659
+ + E ++ I N G+ A +V P PP T++ +D ++ W
Sbjct: 16887 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 16946
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
P+ +GG PV GY +ERK++ S W K+N + +T +++ + EGI YE RV+A N +
Sbjct: 16947 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 17006
Query: 720 GVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
GV + S N++ ++ P P P ++V+ TL+W P G I GY+VE
Sbjct: 17007 GVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKR 17063
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIA 835
W+ A+ V FTV L R FRV+ N AG S+P+ P+T ++
Sbjct: 17064 DLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEV 17123
Query: 836 EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDFD 894
E P+I + R T + GE L GKP P + W +G ++ S R ++ +DF
Sbjct: 17124 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17183
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVEW 953
+ V+ A R D G+Y L + + ++V+++ GPP V V V + W
Sbjct: 17184 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 17243
Query: 954 QAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I Y V+K + + W V S V+ L+ GNEY FR+ N G
Sbjct: 17244 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 17303
Query: 1014 ----LSDSPGVSKN 1023
L +P + KN
Sbjct: 17304 VGEPLESAPVLMKN 17317
Score = 210 bits (535), Expect = 5e-54
Identities = 152/568 (26%), Positives = 255/568 (44%), Gaps = 40/568 (7%)
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE 527
T +WYK+ E++ + + + + ++I D + G Y S SA
Sbjct: 20406 TIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASAT----- 20460
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
I+V+ + K PP ++ T+E +++ PP K
Sbjct: 20461 IRVQILDKPGPPGGPIEFKTVTAEK-------------ITLLWRPPADDGGAKITHYIVE 20507
Query: 588 TEGRTRI------EKRVDCSSFVIESAQ--REDEGRYTIKVTNPVG-----EDVASIFLQ 634
+R+ E +C +I + + + +E + ++ N G E + +
Sbjct: 20508 KRETSRVVWSMVSEHLEEC---IITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKN 20564
Query: 635 VVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT 694
P PP +T + ++ +VW P+ DGG ++GY +E++ K S W K+ E
Sbjct: 20565 AFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR 20624
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDT 751
+T + T + E Y+ RV AVNA G S+PS K PI P P + + D T +
Sbjct: 20625 DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKS 20684
Query: 752 TTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLPTGARILFR 810
+ TL W P G + GY+VE EEW +T+ V + V NL G FR
Sbjct: 20685 SITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFR 20744
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VN AG+ EP + +PV ++I E P+I L LR + I K GE + +++PF+G+P P
Sbjct: 20745 VSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPP 20804
Query: 871 QVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI-ENMKDTATIRIR 928
V W K L + +R + +D ++ + Q R+D+G+Y L+++ ++T+ ++
Sbjct: 20805 TVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVK 20864
Query: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
V++ + VK V + W P DG S I+ Y ++K D W V +
Sbjct: 20865 VLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS 20924
Query: 989 TSCTVSDLIVGNEYYFRVYTENICGLSD 1016
TS + DL ++FRV EN G+ +
Sbjct: 20925 TSFKLIDLSEKTPFFFRVLAENEIGIGE 20952
Score = 209 bits (532), Expect = 1e-53
Identities = 154/579 (26%), Positives = 261/579 (45%), Gaps = 27/579 (4%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK-WYKNGVEVRPSK-RITISHVGRFHKLVIDDVRPEDE 505
+ V A E V + ++ + + W K+G E+ + R+ I + LV+ D D
Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18279
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G Y LS + I V+ + + PP+ L +G T+E + A N D
Sbjct: 18280 GQYIL-----KLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL--AWNPPLQD 18332
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNP-- 623
++ ++ ++ T+ T++ V ++ + +E + + N
Sbjct: 18333 GGAN-----ISHYII-EKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 18386
Query: 624 VGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
+GE + S + + P PP ++++ +D ++ W P+ DGG + GY++E++ K
Sbjct: 18387 IGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK 18446
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGV---SQPSMNTKPFMPIAPT 737
RW K N + T+ T + EG YE RV A NA GV S+PS+ + + P
Sbjct: 18447 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP 18506
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-- 795
P + V D + ++ +L W P G + GY+VE ++EW T P G
Sbjct: 18507 GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTC-TPPTGLQGKQ 18565
Query: 796 FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG 855
FTV L FR+ +N G EPATL V +E EPP+I L LR+ + +
Sbjct: 18566 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18625
Query: 856 EQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L L V +G+P P+V W K L T R + + T+ + R DSG Y L+++
Sbjct: 18626 ATLRLFVTIKGRPEPEVKWEKAEGIL-TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 18684
Query: 916 IENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ TA + +RV++ P+N+ ++EV + + W+ P DG ++I Y V+K +
Sbjct: 18685 NNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETT 18744
Query: 976 TMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
+ + T+ + +L G YYFRV N G+
Sbjct: 18745 RKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783
Score = 208 bits (529), Expect = 3e-53
Identities = 149/504 (29%), Positives = 229/504 (45%), Gaps = 42/504 (8%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE 613
I+V+ G KL + V P P +W K + ++ T + V +S R D
Sbjct: 7899 IIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSV-RADA 7957
Query: 614 GRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGY 673
G YTI + N +G ASI ++V+ +P P + ++ + + + L WEPP +DGG P+ Y
Sbjct: 7958 GIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHY 8017
Query: 674 LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM- 732
++ER++ G + ++ + + ++ +I Y RV AVN +G + P +
Sbjct: 8018 VLERREAGRRTYIPV-MSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8076
Query: 733 --PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP 790
P P P+ + V + T T+ W+PP G I GY++E +G E W N
Sbjct: 8077 QDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL 8136
Query: 791 VERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
V +T K L G FRV N AG SEP+ P + + PK+ LR +
Sbjct: 8137 VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSL 8192
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKG------------GAPLD---------------- 882
K G+++ L G P P + W K APL
Sbjct: 8193 EVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLP 8252
Query: 883 -TSRVHVRTS-DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVM 940
T R+ + S ++ VR + R D G Y + V+ ++ A + V++ GPPIN +
Sbjct: 8253 LTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV 8312
Query: 941 VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKAD--KKTMEWFNVYERNRHTSCTVSDLIV 998
+++ T+ L +W+ P DDG SEI+ Y ++K D K EW V RH +V+ LI
Sbjct: 8313 FEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIE 8372
Query: 999 GNEYYFRVYTENICGLSDSPGVSK 1022
G EY FRV EN G P VSK
Sbjct: 8373 GKEYLFRVRAENRFG-PGPPCVSK 8395
Score = 205 bits (522), Expect = 2e-52
Identities = 154/585 (26%), Positives = 255/585 (43%), Gaps = 40/585 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E + +V + + T +W + E+ S R I + L++ D D G
Sbjct: 17138 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 17197
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y A S S +N V+ + + PP+ + +G TSE
Sbjct: 17198 QYILRASNVAGSKSFPVN-----VKVLDRPGPPEGPVQVTGVTSEKC------------- 17239
Query: 567 SITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
S+T PP ++ ++ ++ T+ T + V +S + +E + I
Sbjct: 17240 SLTWSPPLQDGGSDISHYVV-EKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMA 17298
Query: 621 TNPVG-----EDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
N G E + +P PP+++ +T++ +D + W P DGG + GY+V
Sbjct: 17299 VNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV 17358
Query: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFM 732
E++ + RW+K N T+ T + E YE RV A NA GV +PS T K
Sbjct: 17359 EKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACD 17418
Query: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW---VPANTE 789
P+ P + + D T + TL W P G I GY+VE C EEW P
Sbjct: 17419 PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17478
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
V R F + L RV +N G E ++ V + E P++ L LR+
Sbjct: 17479 RVTR--FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG 17536
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE 909
+ + G + +PF+G+P P++ W++ T +V + T + R+D+G+
Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGK 17595
Query: 910 YELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFV 969
Y L ++ + +A + ++V++ GPP N+ VKEV +A + W+ P DG +++ Y +
Sbjct: 17596 YILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17655
Query: 970 QKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGL 1014
K + + NV + TS V +L G YYFRV EN G+
Sbjct: 17656 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 17700
Score = 205 bits (521), Expect = 2e-52
Identities = 150/561 (26%), Positives = 249/561 (44%), Gaps = 34/561 (6%)
Query: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
W K+G ++ + R+ + L I + +D G YT A + + L+ + ++
Sbjct: 17848 WVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE- 17906
Query: 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVF---- 585
K PP + V +++ D V I+ EPP +
Sbjct: 17907 ----KPGPP--------------VGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 17948
Query: 586 -TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVP 639
TTT + V ++ I + E ++ I N G+ D ++ +Q P
Sbjct: 17949 DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 18008
Query: 640 DPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYE 699
PP +TS+ +D ++ W P+ DGG + GY +E+K+K S W+KLN +T ++
Sbjct: 18009 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18068
Query: 700 STKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
+T + EG+ YE +V A N +G+ +PS ++ F+ P P +T TLKW+
Sbjct: 18069 TTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKK 18128
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G I GY+VE W+ A+ V FTV L R FRV+ N AG
Sbjct: 18129 PAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGN 18188
Query: 820 -SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGG 878
SEP+ + +T R+ + P L + + GE L +GKP P VVW+K G
Sbjct: 18189 FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDG 18248
Query: 879 APLD--TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
L+ +R+ ++++ T V+ R+D G+Y L + + I ++V+++ GPP
Sbjct: 18249 KELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPP 18308
Query: 937 IN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+ V V + W P DG + I Y ++K + + W V + + V+
Sbjct: 18309 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTK 18368
Query: 996 LIVGNEYYFRVYTENICGLSD 1016
L+ GNEY FRV N G+ +
Sbjct: 18369 LLPGNEYIFRVMAVNKYGIGE 18389
Score = 204 bits (519), Expect = 4e-52
Identities = 159/589 (26%), Positives = 267/589 (45%), Gaps = 45/589 (7%)
Query: 448 LTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
LT+KA + V K K W K G ++RPS I+ L I +D
Sbjct: 13891 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDA 13950
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
G+YT K+ +++ V VP P ++ S ++E A
Sbjct: 13951 GEYTITATN---PFGTKVEHVKVTVLDVPGPPGP---VEISNVSAEKA------------ 13992
Query: 566 VSITGEPP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619
++T PP P+ +++ ++ T+ T + + + V + +E + +
Sbjct: 13993 -TLTWTPPLEDGGSPIKSYIL-EKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVS 14050
Query: 620 VTNPVG--EDVASIFLQVVD---VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL 674
N G E V S +++VD P PPE +++V ++ A + W+ P+ DGG +TGY
Sbjct: 14051 AVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYH 14110
Query: 675 VERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-- 732
VER++K S RW++ ++ + T + EG YE RV A N G+ PS + +
Sbjct: 14111 VERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMK 14170
Query: 733 ----PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
P P S P V D T + +L W P+ G I GY+VE+ G E W+ T
Sbjct: 14171 DAAYPPGPPSNPH---VTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTT 14227
Query: 789 EPVERCG-FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLR 847
R F V +L T + FR+ +N AG EPA + V I E P L LR
Sbjct: 14228 GTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAELR 14286
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDS 907
+T + + G + + VP +G+P P+V WTK L +R ++ ++ T+ + + R D+
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRYDT 14345
Query: 908 GEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGY 967
G++ ++++ K + + +RV++ GP +N+ ++ + + W P DG S I Y
Sbjct: 14346 GKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNY 14405
Query: 968 FVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V+K + + + + V+ L G EY+FRV EN G+ +
Sbjct: 14406 IVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14454
Score = 203 bits (517), Expect = 7e-52
Identities = 166/605 (27%), Positives = 260/605 (42%), Gaps = 40/605 (6%)
Query: 448 LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+ V A E ++ + + T +W K E+ + R+ I L + D D G
Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16115
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV-----VVAGNK 561
+Y A S +N V+ + + PP+ + SG T+E + + G
Sbjct: 16116 NYILKAKNVAGERSVTVN-----VKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGS 16170
Query: 562 LRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVT 621
++ + W T ++ V S + +E + I
Sbjct: 16171 DIINYIVERRETSRLVW-------------TVVDANVQTLSCKVTKLLEGNEYTFRIMAV 16217
Query: 622 NP--VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
N VGE + S + VPD P+A +T+V +D I+VWE P DGG + GY++E
Sbjct: 16218 NKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLE 16277
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT---KPFMP 733
++ K RW + + + E T +IE YE RV A NA G+S+PS + K P
Sbjct: 16278 KRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDP 16337
Query: 734 IAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP--V 791
I P + V D+T ++ L W P G I GY+VE C EW T P +
Sbjct: 16338 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMC-TPPTGI 16396
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
+ V+ L FR+ +N AG E A + P+ + E E P I L LR+
Sbjct: 16397 NKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 16456
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
+ G L L VP +G+P P+V W K + + + TS F T + R DSG+Y
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF-TSLVLDNVNRYDSGKYT 16515
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
L+++ + +A + +RV++ PP+N+ V E+ + + W+ P DG S+I Y V+K
Sbjct: 16516 LTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK 16575
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
+ + V S + L G YYFRV EN G+ G+ TA +K
Sbjct: 16576 REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI----GLPAQTADPIKVA 16631
Query: 1032 ITFKP 1036
+P
Sbjct: 16632 EVPQP 16636
Score = 203 bits (516), Expect = 9e-52
Identities = 157/575 (27%), Positives = 257/575 (44%), Gaps = 39/575 (6%)
Query: 462 VSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
V D V GK W K E+ +++++ + G+ VI D G YT
Sbjct: 22569 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22628
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
+ K + +KV LD G + + V K L S+ E
Sbjct: 22629 S---GTKAVSVMVKV------------LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA 22673
Query: 576 A-TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
T + T+ +E S+V+ + +E + ++ N G V
Sbjct: 22674 EITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP 22733
Query: 635 VV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLN 689
+V +P PP G++ I+ W P DGG ++ YLV++++K S RW ++N
Sbjct: 22734 IVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVN 22793
Query: 690 FE-VFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
+ V +T + T ++EG Y+ RV AVNA G S+PS + +P P S P
Sbjct: 22794 KDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPR- 22852
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP-VERCGFTVKNL 801
V D T + +L W P G I GY++E + +++W +T + FTV +L
Sbjct: 22853 --VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDL 22910
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G + FRV VN+ G SE + + E E P + L L++T + G L L+
Sbjct: 22911 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM 22970
Query: 862 VPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKD 921
V G+P P + W+K G L SR + T++ ++ V + R D+G+Y + + ++ K
Sbjct: 22971 VSVSGRPPPVITWSKQGIDL-ASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23029
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
+AT+ ++V + GP +V VKEV + + W+ P DG + + Y V+K + +
Sbjct: 23030 SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKT 23089
Query: 982 VYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
V + T +S L+ G YYFRV ENI G+ +
Sbjct: 23090 VTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23124
Score = 202 bits (515), Expect = 1e-51
Identities = 126/404 (31%), Positives = 190/404 (47%), Gaps = 12/404 (2%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP P+ ++SV + + WE P YDGG PVTGY +E K S+RW ++N + T
Sbjct: 9819 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 9878
Query: 698 ----YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTD 750
Y+ T +IEG Y+ RV+A+NA GV S+ + P PIAP P + D T
Sbjct: 9879 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVT-DWTK 9937
Query: 751 TTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
++ L+W PP + G + GY+VEY EG EEW + V V L GA FR
Sbjct: 9938 SSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFR 9997
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRP 870
V VNIAG EP + + +++ P ++L +R + G + ++ GKP P
Sbjct: 9998 VRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP 10057
Query: 871 QVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
V W L + T+ + ++ RS G Y L + E + TI + V+
Sbjct: 10058 TVTWNMNERTL-PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 10116
Query: 931 EKAGP-PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT 989
+ GP + + + + W +P+DDG S I Y ++K + W V
Sbjct: 10117 DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ 10176
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
+ TV LI G Y+FR+ EN G+ P V + A +++ IT
Sbjct: 10177 NATVQGLIQGKAYFFRIAAENSIGM--GPFVETSEALVIREPIT 10218
Score = 201 bits (510), Expect = 4e-51
Identities = 227/907 (25%), Positives = 363/907 (40%), Gaps = 108/907 (11%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V ++ E++ KWF+N + I SSKY+ L I L D A Y
Sbjct: 6153 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6212
Query: 327 EVAVKDE-----KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKD 381
V++ + K L V+E + IV PL+D + V +V+ + W K+
Sbjct: 6213 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6272
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEV 441
G E+ F R ++ D +H+L D D G Y V + AEL++ E E
Sbjct: 6273 GEEVP----FDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEF 6328
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
++ + D TV + AVF C++S EK KWY+NG E++ K+ G H+L+I D R
Sbjct: 6329 VEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCR 6388
Query: 502 PEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
+DE +Y V D + A+L EI VE + PP+ L+ G + + + N
Sbjct: 6389 LDDECEYACGVEDRKS---RARLFVEEIPVEII---RPPQDILEAPG---ADVVFLAELN 6439
Query: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
K +++V V ++GD+ +EG +I + C + D+G Y
Sbjct: 6440 KDKVEVQWLRNNMVV---VQGDKHQMMSEG--KIHRLQIC------DIKPRDQGEYRFIA 6488
Query: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL-VERKK 679
+ A L++ P +I + +D + D GKP+T + +
Sbjct: 6489 K----DKEARAKLELAAAP------KIKTADQDLVV--------DVGKPLTMVVPYDAYP 6530
Query: 680 KGSQRWMKLNFEVFT---ETTYEST--KMIE---GILYEMRVFAVNAIGVSQPSMNTKPF 731
K W K N + T +TT E T +++E G ++ N G ++ +N K
Sbjct: 6531 KAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVI 6590
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
P +L V + D +L W P G I GY+VE + WV A T+
Sbjct: 6591 DVPGPVR---NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLA-TDRA 6646
Query: 792 ERCGFTVKNLPT-GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTY 850
E C FTV L G LFRV N G EP PV R + P P ++ T
Sbjct: 6647 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITD 6704
Query: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---FDTVFFVRQAARS-- 905
+ + G L P GGA + + +R +DT VR S
Sbjct: 6705 VNRFGVSLTWEPPEY----------DGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSAT 6754
Query: 906 -----DSGEYELSVQIEN-----MKDTATIRIRV---VEKAGPPINVMVKEVWGTNALVE 952
+ EY V+ +N AT ++V +E+ PP+N+ + ++ ++
Sbjct: 6755 VTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLK 6814
Query: 953 WQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENI 1011
W+ P DG S I+GY +++ ++ W + + V+ L GN+Y +RV EN
Sbjct: 6815 WEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENK 6874
Query: 1012 CGLSD-SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
G+SD S + TA T +K+ + P +T L+
Sbjct: 6875 AGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPST------------ 6922
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
G+P+P W + + + L I D G YT + N +
Sbjct: 6923 --GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 6980
Query: 1131 AECKLEV 1137
E + V
Sbjct: 6981 GEIDVNV 6987
Score = 201 bits (510), Expect = 4e-51
Identities = 147/489 (30%), Positives = 221/489 (45%), Gaps = 29/489 (5%)
Query: 538 PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKR 597
PP++ LD T + I V G +R+ + G P P TW K +V EKR
Sbjct: 11408 PPEVELDV---TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR-------EKR 11457
Query: 598 VDCSSFV------IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVG 651
VD + I+ A R D G+Y I N G S + V+D P P + +++T+V
Sbjct: 11458 VDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11517
Query: 652 EDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
++ + WE P+ +GG +T ++VE +K + W + +V ++ Y
Sbjct: 11518 KENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYF 11575
Query: 712 RVFAVNAIGVSQPSMNTK-PFMPIAPTS---EPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
RV A N +GV P++ TK P + I P EP +L + D T LKWR P+ G
Sbjct: 11576 RVCAENKVGVG-PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 11634
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y VE L+GS++W + ++ + V FRV N G S+ +
Sbjct: 11635 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK-TE 11693
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-- 885
V ++E + P + L L K G+ + L +GKP P+V WTK D +R
Sbjct: 11694 EVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 11751
Query: 886 -VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEV 944
V + T + F + +A RSD G+Y ++ A + V++K GP N+ + +V
Sbjct: 11752 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDV 11811
Query: 945 WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004
V W P+DDG EI Y ++K + K M W TV+ LI GNEY F
Sbjct: 11812 SSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIF 11871
Query: 1005 RVYTENICG 1013
RV EN G
Sbjct: 11872 RVRAENKIG 11880
Score = 200 bits (508), Expect = 7e-51
Identities = 148/582 (25%), Positives = 254/582 (43%), Gaps = 35/582 (6%)
Query: 450 VKASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
VKA EQ + T W K+G ++ + R+ +S L I + ED G Y
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
A S++ + I LD G I V+ + ++I
Sbjct: 18969 ELCVSNSAGSITVPITI---------------IVLDRPGPPGPIRIDEVSCDS----ITI 19009
Query: 569 TGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN 622
+ PP ++ ++ + T+T + + V +S I E ++ + N
Sbjct: 19010 SWNPPEYDGGCQISNYIVEKKETTSTTWHI-VSQAVARTSIKIVRLTTGSEYQFRVCAEN 19068
Query: 623 PVGEDVASIFLQVV-----DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
G+ S VV P PP ++ + ++ W+ P+ DGG V GY +E
Sbjct: 19069 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19128
Query: 678 KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPT 737
K++ S W K N + +T + + + EG++YE RV+A N G+ + S + +P P
Sbjct: 19129 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19188
Query: 738 SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFT 797
P V ++T + +LKW P+ G I GY+VE W+ N ++ F
Sbjct: 19189 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19248
Query: 798 VKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGE 856
V L R FRV N A SEP+ P+ +++ EPP++ + R + K GE
Sbjct: 19249 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19308
Query: 857 QLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
L + G+P P + W K G + + +R + ++D T+ V+ R D+G+Y L+++
Sbjct: 19309 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLK 19368
Query: 916 IENMKDTATIRIRVVEKAGPPINVM-VKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
+ + +V++K GPP + + + + W P++DG ++I Y V+K +
Sbjct: 19369 NVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRET 19428
Query: 975 KTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
+ W + TSC V+ L+ GNEY FRV N G+ +
Sbjct: 19429 SHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 19470
Score = 198 bits (504), Expect = 2e-50
Identities = 117/410 (28%), Positives = 204/410 (49%), Gaps = 22/410 (5%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTET- 696
+P PP ++ + + ++ W PP+ +GG P+TGY +E++++GS W +++ T+
Sbjct: 9101 LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9160
Query: 697 ----TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVT 749
+ +++EG+ Y+ R A+NA G+ PS + P + PI P P V+D T
Sbjct: 9161 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 9220
Query: 750 DTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEP---VERCGFTVKNLPTGAR 806
++ +L W+PP + G I GY+VE EG+ +W N EP + C V NL +
Sbjct: 9221 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVN-EPDKLITTCECVVPNLKELRK 9279
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
FRV VN AG SEP+ + +I E P++ + + + K G Q+ + +G
Sbjct: 9280 YRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKG 9339
Query: 867 KPRPQVVWTKGGAPLDTSR--VH-------VRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+P P+ W G + VH + T++ +V + + RS +G+Y ++ + +
Sbjct: 9340 RPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNK 9399
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+ TA R++V++ GPP ++ V ++ + + W+ P DDG I GY ++K
Sbjct: 9400 AGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK 9459
Query: 978 EWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS-PGVSKNTAR 1026
W V T+ V DL+ +Y+FRV EN G+ + + TAR
Sbjct: 9460 AWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTAR 9509
Score = 198 bits (503), Expect = 3e-50
Identities = 169/622 (27%), Positives = 268/622 (43%), Gaps = 40/622 (6%)
Query: 430 AELIVEEKQLEVLQDIADLT-----VKASEQAVFKCEVSDE---KVTGKWYKNGVEVRPS 481
+ +I++E Q+E D+ +T KA +S KVT W + ++ +
Sbjct: 22137 SSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT--WKLEEMRLKET 22194
Query: 482 KRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKI 541
R++I+ L + D D G Y L +A + + V + + P
Sbjct: 22195 DRVSITTTKDRTTLTVKDSMRGDSGRYFLT-----LENTAGVKTFSVTVVVIGRPGPVTG 22249
Query: 542 HLDCSGKTSENAIVVVAGNKLRLDVSITG------EPPPVATWLKGDEVFTTTEGRTRIE 595
++ S ++E+ ++ K IT E A L V T T +
Sbjct: 22250 PIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22309
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
K ++ S F + S R V+ P+ E I P P + V +
Sbjct: 22310 KYMEYS-FRVSSENR-------FGVSKPL-ESAPIIAEHPFVPPSAPTRPEVYHVSANAM 22360
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
+ WE P +DGG + GY VE+K++ + W+K N E Y+ T ++EG+ Y+ R +A
Sbjct: 22361 SIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYA 22420
Query: 716 VNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE- 774
+NA GVS+ S ++P M P P V DVT +T +L W P G + GY++E
Sbjct: 22421 LNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIER 22480
Query: 775 --YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-RSEPATLAQPVTI 831
G W+ N V FTV L G FRV+ N AG S+ + PVT
Sbjct: 22481 KPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTC 22540
Query: 832 REIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVR 889
R+ PPK L L + + G L L GKP P+++WTKG LD +V ++
Sbjct: 22541 RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQ 22600
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 949
+ ++ RSDSG+Y L+V+ + ++ ++V++ GP + V V
Sbjct: 22601 YTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKC 22660
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ W P++DG +EI Y V++ + + W V S V+ LI NEY FRV
Sbjct: 22661 TLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22720
Query: 1010 NICG----LSDSPGVSKNTARI 1027
N G + P V++N+ I
Sbjct: 22721 NKYGPGVPVESEPIVARNSFTI 22742
Score = 197 bits (501), Expect = 5e-50
Identities = 164/594 (27%), Positives = 258/594 (43%), Gaps = 46/594 (7%)
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGK------WYKNGVEVRPSKRITISHVGRFHKL 495
L+ + DL A E + F+ ++ + GK W K + R+++ L
Sbjct: 13487 LKGLPDLCYLAKENSNFRLKIP---IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 13543
Query: 496 VIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIV 555
++ D + D G YT A K + IKV V K P + T+E
Sbjct: 13544 IVYDCQKSDAGKYTITLKNVA---GTKEGTISIKV--VGKPGIPTGPIKFDEVTAEA--- 13595
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKGDEVFT-TTEGRTRIEKR-VDCSSFVIESA---QR 610
+++ PP G E+ E R + + V C+S V ++ R
Sbjct: 13596 ----------MTLKWAPPKDDG---GSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 13642
Query: 611 EDEG-RYTIKVTNP----VGEDVAS---IFLQVVDVPDPPEAVRITSVGEDWAILVWEPP 662
EG YT +V+ VGE + S + DVPD P I V D L W P
Sbjct: 13643 LHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDP 13702
Query: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
GG P+TGY +E K++ S W + N ++ T + EG+ YE RV A+N GV
Sbjct: 13703 KKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVG 13762
Query: 723 QPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+PS+ ++P + + P P V ++T + TL W P G + GY+VE S+
Sbjct: 13763 KPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS 13822
Query: 783 WVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR-SEPATLAQPVTIREIAEPPKIR 841
W+ AN V C FTV +L G + FR+ N AG S P+ + + ++ E P I
Sbjct: 13823 WMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIV 13882
Query: 842 LPRHLRQTYIRKVGEQLNL-VVPFQGKPRPQVVWTKGGAPLDTSRV-HVRTSDFDTVFFV 899
L ++ K G+ + L + GKP P+ W+K G + S + + ++ ++ +
Sbjct: 13883 LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTI 13942
Query: 900 RQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
+ A R D+GEY ++ +++ V++ GPP V + V A + W P +D
Sbjct: 13943 KYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLED 14002
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1013
G S I Y ++K + + W V E + + LI GNEY FRV N G
Sbjct: 14003 GGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14056
Score = 192 bits (489), Expect = 1e-48
Identities = 116/380 (30%), Positives = 190/380 (50%), Gaps = 8/380 (2%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP A+ + V + L WEPP DGG+P+ Y++E+K++ RW+K + +
Sbjct: 7687 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7746
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T +IEG + +V A N GV PS T+ P +P S PL L V D +
Sbjct: 7747 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7806
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTV-KNLPTGARILFRVVGV 814
W+PP + G I GY VE C G+E+W+ N+ P++ F V + + + RV V
Sbjct: 7807 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 7866
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
N G SEP+ +++ V ++ P I L H I GE+L++ VPF+ P P V W
Sbjct: 7867 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 7923
Query: 875 TKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKA 933
K G + S R+ ++ V ++ R+D+G Y ++++ + TA+I ++V+
Sbjct: 7924 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 7983
Query: 934 GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTV 993
GP ++ ++ ++ + W+ P+ DG + I+ Y +++ + + V S TV
Sbjct: 7984 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 8043
Query: 994 SDLIVGNEYYFRVYTENICG 1013
DLI EY+FRV N G
Sbjct: 8044 KDLIPNGEYFFRVKAVNKVG 8063
Score = 191 bits (485), Expect = 3e-48
Identities = 127/440 (28%), Positives = 205/440 (46%), Gaps = 10/440 (2%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE----DVASIFLQV-VDVPD 640
T+T T + V + + +E ++ IK N G D A + +++ P
Sbjct: 20115 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPG 20174
Query: 641 PPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYES 700
PP +T+V + + W P+ +GG V GY +E K + S W K N V T ++
Sbjct: 20175 PPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKV 20234
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPP 760
T + G++YE RV+A NA GV +PS ++P + I P ++ + D++ + +L W+ P
Sbjct: 20235 TTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQP 20294
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR- 819
G I GY+VE W A+ V F + L ++ FRV N G
Sbjct: 20295 AFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSI 20354
Query: 820 SEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGA 879
S P+ + P+T + P I LP + + G + L GKP P + W K
Sbjct: 20355 SNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDK 20414
Query: 880 PLDTSRVHV--RTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPI 937
L T+ + T+D ++ ++ A R +SG YEL ++ +ATIR+++++K GPP
Sbjct: 20415 ELQTNALVCVENTTDLASI-LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPG 20473
Query: 938 N-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ K V + W+ P DDG ++I Y V+K + + W V E T + +
Sbjct: 20474 GPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI 20533
Query: 997 IVGNEYYFRVYTENICGLSD 1016
I GNEY FRV N G+ +
Sbjct: 20534 IKGNEYIFRVRAVNKYGIGE 20553
Score = 189 bits (480), Expect = 1e-47
Identities = 117/378 (30%), Positives = 174/378 (46%), Gaps = 7/378 (1%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
PD P+ + V + ++ W P D G P+ GY +E+++ S W ++N +
Sbjct: 8406 PDAPDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKA 8464
Query: 699 ESTKMIEGILYEMRVFAVNAIG---VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTL 755
++EG+ Y RV A NA G S PS PI+P P+ + D + TT L
Sbjct: 8465 NVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVT-DTSSTTIEL 8523
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W PP G G I GY V+ L G+ EW + ++ +TVK + GA RV VN
Sbjct: 8524 EWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVN 8583
Query: 816 IAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
AG P QPVT+ E EPP + L ++ G+ L + G+P P VWT
Sbjct: 8584 AAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWT 8642
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP 935
K LD RV + + ++ A R D G Y ++ A R+ V + GP
Sbjct: 8643 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGP 8702
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSD 995
+++ L+ W P+DDG SEI G+ +++ D K W E R + C ++
Sbjct: 8703 VLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER-SKCDITG 8761
Query: 996 LIVGNEYYFRVYTENICG 1013
L+ G EY FRV +N G
Sbjct: 8762 LLEGQEYKFRVIAKNKFG 8779
Score = 171 bits (432), Expect = 5e-42
Identities = 168/618 (27%), Positives = 263/618 (42%), Gaps = 61/618 (9%)
Query: 429 EAELIVEEKQLEVLQDI---ADLTVKASEQAVFKCEVS---DEKVTGKWYKNGVEVRPSK 482
E + + ++ E+ D+ A LTVKA + V+ + K+T W K + ++ K
Sbjct: 7181 EIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT--WTKADMILKQDK 7238
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
RITI +V + + I D + D G Y A+++ + + ++V + K PP
Sbjct: 7239 RITIENVPKKSTVTIVDSKRSDTGTYII----EAVNVCGRATAV-VEVNVLDKPGPPAA- 7292
Query: 543 LDCSGKTSENAIVV------VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
D + T+E+ ++ G+K+ + + W K T + + K
Sbjct: 7293 FDITDVTNESCLLTWNPPRDDGGSKI-TNYVVERRATDSEVWHKLSS--TVKDTNFKATK 7349
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
+ ++ A G V PV + Q D P PP + + + +D
Sbjct: 7350 LIPNKEYIFRVAAENMYG-----VGEPVQASPITAKYQ-FDPPGPPTRLEPSDITKDAVT 7403
Query: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
L W P DGG P+TGY VER + +W++ N +TTY + Y RV A
Sbjct: 7404 LTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAE 7463
Query: 717 NAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
N G +PS +T+P + PI P P V+DV T+ L W P G I+ Y++
Sbjct: 7464 NLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVI 7523
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E G++EWV E V + L G FRV VN AG SEP+ + PV RE
Sbjct: 7524 EMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCRE 7582
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKP------RPQVVWTKGGAPLDT-- 883
PP PR L I K L VP + G P + V KG +DT
Sbjct: 7583 KLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTV 7640
Query: 884 --SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRVVEKAGPPIN 938
++ V +++ R AA + G+ + + +IE+ KDT T GPP
Sbjct: 7641 KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYT-EIEDSVLAKDTFT-------TPGPPYA 7692
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT--VSDL 996
+ V +V + ++W+ PK+DG I Y ++K ++ W + C V+D+
Sbjct: 7693 LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKA-GKTAGPDCNFRVTDV 7751
Query: 997 IVGNEYYFRVYTENICGL 1014
I G E F+V EN G+
Sbjct: 7752 IEGTEVQFQVRAENEAGV 7769
Score = 169 bits (427), Expect = 2e-41
Identities = 134/515 (26%), Positives = 221/515 (42%), Gaps = 40/515 (7%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
+ +++ D+T K E A C++ + KWY+ G E+ S++ +S GR H L +
Sbjct: 24038 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24097
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
EDEG YT + + L Q P+ H G + G
Sbjct: 24098 EEQEDEGVYTCIATNEVGEVETSSKLL--------LQATPQFH---PGYPLKEKYYGAVG 24146
Query: 560 NKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE-GRYTI 618
+ LRL V G P P TW G ++ +E T IE + V+++ QR+ G+Y +
Sbjct: 24147 STLRLHVMYIGRPVPAMTWFHGQKLLQNSENIT-IENTEHYTHLVMKNVQRKTHAGKYKV 24205
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
+++N G A + +++ D PD P + I ++ ++ A++ W+PP DGG +T Y+VE+
Sbjct: 24206 QLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEK 24265
Query: 678 -KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP----------SM 726
+ K W ++ + + TT + E Y RV A N G+S P S
Sbjct: 24266 CEAKEGAEWQLVSSAI-SVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24324
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
KP P PT + VT + + W+PP G I Y +E + +W+
Sbjct: 24325 FEKPGAPGKPT-------ITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISV 24377
Query: 787 NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHL 846
TE + F+VKNL G FRV N+ G SE + +++P+T + L
Sbjct: 24378 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 24437
Query: 847 RQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF---FVRQAA 903
R +R LV G P+P V W + G + + R +F + +
Sbjct: 24438 RNLNVR-YQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVT 24496
Query: 904 RSDSGEYELSV--QIENMKDTATIRIRVVEKAGPP 936
D+ Y++ Q ++ TA++ + V K P
Sbjct: 24497 DDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP 24531
Score = 156 bits (395), Expect = 9e-38
Identities = 95/314 (30%), Positives = 153/314 (48%), Gaps = 13/314 (4%)
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V + + PP+I L + K+ + V AG + LD ++ G+P P +W K + E
Sbjct: 12787 VTILAENVPPRIDLSVAMKS---LLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE 12843
Query: 590 GRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
G +R C + + S R+D G YTI N G A+I L+V+D P PP +V+I
Sbjct: 12844 GIKMAMQRNLC-TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINK 12902
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+ D A+L WEPP+ DGG +T Y+V++++ W +++ V T+ K+IEG Y
Sbjct: 12903 MYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEY 12961
Query: 710 EMRVFAVNAIGV-----SQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
+ R+ A N GV ++P++ P+ P P ++ ++T T+ W+PP G
Sbjct: 12962 QFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP---VISNITKDHMTVSWKPPADDG 13018
Query: 765 AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
I GYL+E + W N +P+ L G FRV +N AG +P+
Sbjct: 13019 GSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13078
Query: 825 LAQPVTIREIAEPP 838
++ R+ PP
Sbjct: 13079 ASKAAYARDPQYPP 13092
Score = 154 bits (388), Expect = 6e-37
Identities = 221/934 (23%), Positives = 348/934 (37%), Gaps = 146/934 (15%)
Query: 271 GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV 330
G + + E++ + ++W +N + K+ + GK L I D Y
Sbjct: 6429 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 6488
Query: 331 KDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSE-EGAQVMWMKDGVELTRE- 388
KD++ +L + P I T +D V VG + M V A+ W K+ L+ +
Sbjct: 6489 KDKEARAKLELAAAPK-IKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT 6547
Query: 389 -DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
D+ + F+ + + D+GRY+++ +AE + K ++V + +
Sbjct: 6548 IDTTAEQTSFR---------ILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRN 6598
Query: 448 LTVKASEQAVFKCEVS---DEKVT---GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
L V + F EVS +E +T K VE R KR T ++ D
Sbjct: 6599 LEVTET----FDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTW--------VLATDRA 6646
Query: 502 PEDEGDYTFVPDG---YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA 558
E T + G Y +SA+ + + D G I V
Sbjct: 6647 ESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN 6706
Query: 559 GNKLRLDVSITGEPPP------VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
R VS+T EPP + ++ T+ T + R + S +
Sbjct: 6707 ----RFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQ 6762
Query: 613 EGRYTIKVTNPVG---EDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVWEPPMYDG 666
E + ++ N +G A+ F++V D P PP + + + L WEPP+ DG
Sbjct: 6763 EYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDG 6822
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSM 726
G P+ GY++ER ++G W++ N ++ E TY+ T + +G Y RV A N GVS PS
Sbjct: 6823 GSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 6882
Query: 727 NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPA 786
P EP D++ L+ PN I VP+
Sbjct: 6883 ILGPLTADDAFVEP----TMDLSAFKDGLEVIVPNPITI-----------------LVPS 6921
Query: 787 N--TEPVERCGFTVKNLPTGARILFRVVG------VNIAGRSEPA-----------TLAQ 827
P F K L TG R+ + + ++ + RS+ T++
Sbjct: 6922 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981
Query: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD----- 882
+ + IA P P+ L+ I K L P GG+PL
Sbjct: 6982 EIDVNVIARPSA---PKELKFGDITKDSVHLTWEPPDDD----------GGSPLTGYVVE 7028
Query: 883 ----TSRVHVRTSDFDT-------------VFFVRQAARSDSGEYELSVQIE--NMKDTA 923
+ + + DF T + + AR+ G E + E NM A
Sbjct: 7029 KREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPA 7088
Query: 924 TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
T+ PP NV ++ + + W PK+DG S I GY V++ + + +W
Sbjct: 7089 TV-------PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG 7141
Query: 984 ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
E T V+ L G Y +RV N G S S+ T I P +
Sbjct: 7142 EPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRPTEEIQAVDTQEAP------E 7192
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+ K L L V AG L V G P+PK+ W K M +++D + I N
Sbjct: 7193 IFLDVKLLAGL---TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7249
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
T+ I D GTY AVN G A A ++ V
Sbjct: 7250 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 152 bits (385), Expect = 1e-36
Identities = 103/305 (33%), Positives = 150/305 (49%), Gaps = 8/305 (2%)
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLD-VSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
E P I LD T ++ + + AG+ + L+ +SI G+P P ++W K + ++ T+I
Sbjct: 13877 EAPTIVLD---PTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSD-ITQIT 13932
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWA 655
S I+ A R+D G YTI TNP G V + + V+DVP PP V I++V + A
Sbjct: 13933 STPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKA 13992
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
L W PP+ DGG P+ Y++E+++ W ++ E + +TK+I+G Y RV A
Sbjct: 13993 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQGNEYIFRVSA 14051
Query: 716 VNAIGVSQP--SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLV 773
VN G +P S K P P V +VT T T+ W+ P G I GY V
Sbjct: 14052 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14111
Query: 774 EYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE 833
E + S WV A PV V L G+ FRV N AG P+ + V +++
Sbjct: 14112 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14171
Query: 834 IAEPP 838
A PP
Sbjct: 14172 AAYPP 14176
Score = 150 bits (378), Expect = 9e-36
Identities = 188/818 (22%), Positives = 320/818 (39%), Gaps = 114/818 (13%)
Query: 277 MVEISDPDLTLKWFK----NGQEI-------KPSSKYVFENVGKKRI----LTINKCTLA 321
++ IS +TL+W K G+EI + S ++ K+RI TI A
Sbjct: 23942 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24001
Query: 322 DDAAYEVAVKDEKCF-----------TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-V 369
+ + V ++E T+L E P I ++D +G+ +++ + V
Sbjct: 24002 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKEMKDVTTKLGEAAQLSCQIV 24060
Query: 370 SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCE 429
+ W + G EL + +Y+ DG+ H L QED G Y I E
Sbjct: 24061 GRPLPDIKWYRFGKELIQS----RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24116
Query: 430 AE-----LIVEEKQLEVLQDIADLTVKA--SEQAVFKCEVSDEKVTGKWYKNGVEVRPSK 482
E L+ Q + + A S + + W+ ++ S+
Sbjct: 24117 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24176
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
ITI + + LV+ +V+ + Y + LS ++ ++ + +P K
Sbjct: 24177 NITIENTEHYTHLVMKNVQRKTHAGK------YKVQLSNVFGTVDAILDVEIQDKPDK-- 24228
Query: 543 LDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV--ATWLKGDEVFTTTEGRTRIEKRVDC 600
IV+ A L+ I+ +PP +W+ + V E + E ++
Sbjct: 24229 -------PTGPIVIEA--LLKNSAVISWKPPADDGGSWIT-NYVVEKCEAKEGAEWQLVS 24278
Query: 601 SSFVIESAQ----REDEGRY-------TIKVTNPVGEDVASIFLQVVDVPDPPEAVRITS 649
S+ + + + E+ G Y T +++P+ I + P P IT+
Sbjct: 24279 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 24338
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
V +D ++ W+PP DGG + Y +E+++K +W+ + E ET + +IEG+ Y
Sbjct: 24339 VTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEY 24398
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPT--------SEPLHLIVEDVTDTTTTLK----- 756
E RV N G S+ S ++P P + E +L V ++ T K
Sbjct: 24399 EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHP 24458
Query: 757 ------WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
+R I A G+ Y ++ G + + A+ + + V+ G +
Sbjct: 24459 KPIVKWYRQGKEIIADGLK-YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSV--- 24514
Query: 811 VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV--GEQLNLVVPFQGKP 868
S A+L E+ P KI LP+ L GE +++ +PF GKP
Sbjct: 24515 ---------SGTASL-------EVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 24558
Query: 869 RPQVVWTKGGAPLDTSRVH--VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
P + W KG +D + + + T F ++ F R D+G Y + + D T+
Sbjct: 24559 DPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE 24618
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
+ V + PP V V +V + + W P DG S+I Y V+K W V +
Sbjct: 24619 LDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQA- 24677
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNT 1024
R T TV +L Y FRV EN GLS S+ T
Sbjct: 24678 RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 24715
Score = 149 bits (375), Expect = 2e-35
Identities = 110/360 (30%), Positives = 159/360 (44%), Gaps = 37/360 (10%)
Query: 268 VDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYE 327
V G E+S D+ ++W+ G++++PS K V + GK LT+ L D +
Sbjct: 5710 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5769
Query: 328 VAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTR 387
+ KD K LFVKEPPV PLEDQ V G + EVS E A+V W K+G E+ +
Sbjct: 5770 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 5829
Query: 388 EDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD 447
+Y DG+ L+ D ED Y + L V +E L+ + D
Sbjct: 5830 ----SKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTD 5885
Query: 448 LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGD 507
L V+ E A F+CE+S E KW+K+G E++ K+ I G LVI+ +DE +
Sbjct: 5886 LQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAE 5945
Query: 508 YTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVS 567
Y+ + S L LE + + + + SE + KL +VS
Sbjct: 5946 YSC--EVRTARTSGMLTVLEEEAVFTKNL--------ANIEVSETDTI-----KLVCEVS 5990
Query: 568 ITGEPPPVATWLKGDEVF-------TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
+P W KGDE TEGR RI VI++A ED G Y ++
Sbjct: 5991 ---KPGAEVIWYKGDEEIIETGRYEILTEGRKRI--------LVIQNAHLEDAGNYNCRL 6039
Score = 149 bits (375), Expect = 2e-35
Identities = 101/318 (31%), Positives = 146/318 (45%), Gaps = 14/318 (4%)
Query: 528 IKVEYVPKQEP---PKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKG-DE 583
+K E V +E P + L SG + V AG+ +RL+ + G+P P W K D
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSG-----VLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDA 11744
Query: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 643
T R +I+ R D S F + A+R D G+Y + TN G VA + V+D P P
Sbjct: 11745 TDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVR 11804
Query: 644 AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKM 703
++I V D + W+PP DGG + Y++E+ + W + V T T T++
Sbjct: 11805 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT-TVTRL 11863
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT---TTLKWRPP 760
IEG Y RV A N IG P+ +KP + +P +VT + T+ W PP
Sbjct: 11864 IEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPP 11922
Query: 761 NRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS 820
G I GY +E + S WVP N + V+NL FRV N G
Sbjct: 11923 EYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIG 11982
Query: 821 EPATLAQPVTIREIAEPP 838
EP+ ++PV ++ EPP
Sbjct: 11983 EPSLPSRPVVAKDPIEPP 12000
Score = 145 bits (366), Expect = 2e-34
Identities = 135/522 (25%), Positives = 214/522 (40%), Gaps = 46/522 (8%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP + VG+ L W P +DGG + Y++E K G+ W+++ V T
Sbjct: 7484 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPT- 7542
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTT 752
T + ++EG Y RV AVN G S+PS + P + + P S P L V ++T T
Sbjct: 7543 TQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7602
Query: 753 TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVV 812
LKW P + G I Y+VE + W +T V+ TV L G+ +FRV
Sbjct: 7603 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVA 7661
Query: 813 GVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKPRP 870
N G+S+ + V ++ P P L + K L P G+P
Sbjct: 7662 AENAIGQSDYTEIEDSVLAKDTFTTPGP--PYALAVVDVTKRHVDLKWEPPKNDGGRPIQ 7719
Query: 871 QVV----------WTKGG---APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
+ V W K G P RV + F VR + G +I
Sbjct: 7720 RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 7779
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM 977
+++D + PP+++ V + + + W+ P+ +G S I+GY V+ T
Sbjct: 7780 SIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTE 7832
Query: 978 EWFNVYERN-RHTSCTVSDLIVGN-EYYFRVYTENICGLSDSPGVSKNTARILKTGITFK 1035
+W V R + V + +V + EY RV N G+S+ +S+N + K
Sbjct: 7833 KWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV--VAKDPDCKP 7890
Query: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
+ + HD +V+ G ++ R P P V W K+ E++ +
Sbjct: 7891 TIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 7937
Query: 1096 ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N L + + DAG YT N+LG A A ++V
Sbjct: 7938 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 137 bits (345), Expect = 6e-32
Identities = 141/569 (24%), Positives = 234/569 (41%), Gaps = 50/569 (8%)
Query: 68 DAVVVAKVNGKELPDKPTIKWFKGKWL----ELGSKSG--ARFSFKESHNSASNVY---T 118
+ V A+V GK+ + + + K++ + K G A F + SH V+
Sbjct: 5054 EGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKND 5113
Query: 119 VELHIGKVVL--GDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKS 176
+LH + VL + ++LE+K D V+ A + LE+ + K
Sbjct: 5114 AKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLH 5173
Query: 177 D-TAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGI 235
D TA E D L K EV ++ K KD +++ P+ G ++ K A
Sbjct: 5174 DKTAVEKDEITL--KCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKA----- 5226
Query: 236 TDLRGMLKRL-----KKAKVEVKKSAAFTKKLDPAYQVDR--GNKIKLMVEISDPDLTLK 288
DL+ + + K K V A K P Y V+ G +E+S+PD+ +
Sbjct: 5227 -DLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ 5285
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLI 348
W GQ + S GKK IL ++ C L + K L VKE P++
Sbjct: 5286 WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIF 5345
Query: 349 VTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIF 408
+TPL D +VF D + EVS E W+K E+T +D R+ KDG +H ++
Sbjct: 5346 ITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDD----RFELIKDGTKHSMVI 5401
Query: 409 SDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVT 468
ED +Y +LI+E +L+ L + D+T K E AVF E+S + +
Sbjct: 5402 KSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIR 5461
Query: 469 GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEI 528
KW+KN + ++ +++ G+ H + D+ +D + +S AKL LE
Sbjct: 5462 VKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRV--EAMGMSSEAKLTVLEG 5519
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
+ K + D +G + I L I+ PV + G E+ +
Sbjct: 5520 DPYFTGKLQ------DYTGVEKDEVI---------LQCEISKADAPVKWFKDGKEIKPSK 5564
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYT 617
+ + + +++ A + D G+YT
Sbjct: 5565 NAVIKADGKK--RMLILKKALKSDIGQYT 5591
Score = 136 bits (342), Expect = 1e-31
Identities = 97/354 (27%), Positives = 155/354 (43%), Gaps = 30/354 (8%)
Query: 551 ENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQR 610
++ IVV AG L+ I G+P P W K + T R I+ + ++ V++ R
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276
Query: 611 EDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKP 669
D G+Y +K++N G I ++V+D P PPE +++T V + L W PP+ DGG
Sbjct: 18277 TDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGAN 18336
Query: 670 VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMN-- 727
++ Y++E+++ W +++ EV Y+ TK++ G Y RV AVN G+ +P +
Sbjct: 18337 ISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGP 18395
Query: 728 ---TKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
P+ P P S P V +T + + W P G I+GY++E + W
Sbjct: 18396 VTACNPYKPPGPPSTPE---VSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18452
Query: 785 PANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N + + V L G FRV N AG EP+ + + PP
Sbjct: 18453 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP------ 18506
Query: 845 HLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVRTSDFD 894
G N V + + W+K GGAP+ V V+ + D
Sbjct: 18507 ----------GPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 18550
Score = 134 bits (338), Expect = 4e-31
Identities = 118/428 (27%), Positives = 186/428 (43%), Gaps = 39/428 (9%)
Query: 430 AELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKW----YKNGVEV-RPSKRI 484
+E +V + + V + DL VK EV+ VT W Y G E+
Sbjct: 10208 SEALVIREPITVPERPEDLEVK---------EVTKNTVTLTWNPPKYDGGSEIINYVLES 10258
Query: 485 TISHVGRFHKLVIDD-------VRPEDEGD-YTFVPDGYALSLSAKLNFLEIKVEYVPKQ 536
+ +FHK+ D+ V+ EGD Y + + K +F + +
Sbjct: 10259 RLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDEL 10318
Query: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
PP +HLD K + + G L +G+P P +W K DE + RT I+
Sbjct: 10319 APPTLHLDFRDK-----LTIRVGEAFALTGRYSGKPKPKVSWFK-DEADVLEDDRTHIKT 10372
Query: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWA 655
+ A+R D G+Y + V N G + VVD P PP V V +D+
Sbjct: 10373 TPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM 10432
Query: 656 ILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFA 715
++ W+PP+ DGG +T Y++E+K+ G WM + +TT + +K++EG Y R+ A
Sbjct: 10433 VISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT-SASAKTTCKVSKLLEGKDYIFRIHA 10491
Query: 716 VNAIGVSQP----SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
N G+S P SM K + P IV +VT + + W P+ G I Y
Sbjct: 10492 ENLYGISDPLVSDSMKAKDRFRV--PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNY 10548
Query: 772 LVEYCLEGSEEWVPANTEPVE-RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVT 830
++E S+ W +P+ F V +L G + FRV N G +P+ ++PV
Sbjct: 10549 ILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVF 10608
Query: 831 IRE-IAEP 837
++ IA+P
Sbjct: 10609 AKDPIAKP 10616
Score = 130 bits (326), Expect = 9e-30
Identities = 119/457 (26%), Positives = 183/457 (40%), Gaps = 38/457 (8%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K G ++ SKR I+ +LVI + D G Y V + K +++++
Sbjct: 23672 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLEN---KCGKKAVYIKVR 23726
Query: 530 VEYVPKQEPPKIHLDC----SGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
V P + D S + S G + L + P A W
Sbjct: 23727 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI-LGYILERREVPKAAWYT----- 23780
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN------PVGEDVASIFLQVVDVP 639
I+ RV +S V++ + E + + N P+ + ++ P
Sbjct: 23781 --------IDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP 23832
Query: 640 DPPE-AVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
+PP + V + L W P DGG VTGY +ERK+ + +W++ N T T Y
Sbjct: 23833 EPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 23892
Query: 699 ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTL 755
T ++ Y+ R+ A N +G+S+ S ++P + P S+P L + ++ + TL
Sbjct: 23893 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTL 23952
Query: 756 KWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVN 815
+W P G I GY VEY G W +N E ++ FT+ L FRV N
Sbjct: 23953 QWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAEN 24012
Query: 816 IAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
G S P A + T E P IR + K+GE L G+P P + W
Sbjct: 24013 ETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTKLGEAAQLSCQIVGRPLPDIKW 24069
Query: 875 TKGGAPLDTSRVHVRTSDFDT-VFFVRQAARSDSGEY 910
+ G L SR + +SD T V + D G Y
Sbjct: 24070 YRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24106
Score = 126 bits (316), Expect = 1e-28
Identities = 97/360 (26%), Positives = 157/360 (43%), Gaps = 24/360 (6%)
Query: 258 FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINK 317
FT KL V++ +++ L EIS D +KWFK+G+EIKPS V + GKKR+L + K
Sbjct: 5523 FTGKLQDYTGVEK-DEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKK 5581
Query: 318 CTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM 377
+D Y +K +L +++ + +V PL +V + E+SE+
Sbjct: 5582 ALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHAN 5641
Query: 378 WMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
W G L + + K++GK H L+ + + G + A L V+ +
Sbjct: 5642 WKLKGEALLQTPDCE----IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPR 5697
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVI 497
+ +L+ + D+TV A E A F CE+S E + +WY G ++ PS ++ G+ H L +
Sbjct: 5698 VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTL 5757
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
DV+ ED G+ + A L E VE+ E + E A V
Sbjct: 5758 RDVKLEDAGEVQLTAKDF--KTHANLFVKEPPVEFTKPLEDQTV--------EEGATAV- 5806
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
L+ ++ E V + G E+ + + + RV VI ED YT
Sbjct: 5807 ------LECEVSRENAKVKWFKNGTEILKSKKYEIVADGRV--RKLVIHDCTPEDIKTYT 5858
Score = 126 bits (316), Expect = 1e-28
Identities = 95/335 (28%), Positives = 146/335 (43%), Gaps = 33/335 (9%)
Query: 526 LEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
L + V + PP I L S + + I V AG + + +TG P P W K + V
Sbjct: 8885 LPLNVVIQDDEVPPTIKLRLSVRG--DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVI 8942
Query: 586 T--------TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVD 637
T E +R E + + S I A RED+G YT+ +N +G ++ ++V D
Sbjct: 8943 EKPTDALQITKEEVSRSEAKTELS---IPKAVREDKGTYTVTASNRLGSVFRNVHVEVYD 8999
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
P PP + +T + + L W+ P+ +GG +T Y+++++ + K +E T T
Sbjct: 9000 RPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRK---KAEWEEVTNTA 9056
Query: 698 YEST----KMIEGILYEMRVFAVNAIGVSQPSMNTK-----PFMPIAPTSEPLHLIVEDV 748
E K+I YE RV AVN G+S + K P+ P +P L
Sbjct: 9057 VEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLA---R 9113
Query: 749 TDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG-----FTVKNLPT 803
T + + W PP G I GY +E EGS W + P+ + G F V L
Sbjct: 9114 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9173
Query: 804 GARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
G + FR + +N AG P+ + P + PP
Sbjct: 9174 GVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPP 9208
Score = 124 bits (311), Expect = 5e-28
Identities = 98/378 (25%), Positives = 161/378 (42%), Gaps = 25/378 (6%)
Query: 274 IKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE 333
I V ++ ++ KW KNG EIK + K L I D A Y
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 334 KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKA 393
L+V+ + ++D +V R EVSE V WMKD EL D
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITD---- 3055
Query: 394 RYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKAS 453
R + +K+ H L+ D G+Y V+ G A+L VE + + + ++ V
Sbjct: 3056 RIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3115
Query: 454 EQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFV 511
++AV + EV+++ V WYK+G+E+ + +V R H++ I + R D G+YTFV
Sbjct: 3116 QRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV 3175
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
S++ YV EPP++ + + V +G R I+G
Sbjct: 3176 AGRNRSSVTL----------YVNAPEPPQVLQEL------QPVTVQSGKPARFCAVISGR 3219
Query: 572 PPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG--EDVA 629
P P +W K +++ +T + + + +IE A ED YT + N G A
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE-AFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 630 SIFLQVVDVPDPPEAVRI 647
S+ ++V +V P + + +
Sbjct: 3279 SLSVEVPEVVSPDQEMPV 3296
Score = 124 bits (310), Expect = 7e-28
Identities = 96/374 (25%), Positives = 160/374 (42%), Gaps = 24/374 (6%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
QV + E+S + +KWFK+G EIK KY + G RIL INKC L D+A Y
Sbjct: 5887 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 5946
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
V+ + L V E + L + +V D +++ EVS+ GA+V+W K E+
Sbjct: 5947 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6006
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
RY +G++ IL+ + ED G Y + + ++ V E E +
Sbjct: 6007 E----TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQ 6062
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
+L + E+A F C +S E +W ++ + + + G+ LV+ D +D G
Sbjct: 6063 NLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMG 6122
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
Y + A +A L +E VP ++ + E VV +V
Sbjct: 6123 TYVVMVG--AARAAAHLTVIEKLRIVVPLKDT---------RVKEQQEVV-----FNCEV 6166
Query: 567 SITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
+ G A W + +E + ++K + + I A +D+ Y + +TN GE
Sbjct: 6167 NTEGAK---AKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQANYNVSLTNHRGE 6222
Query: 627 DVASIFLQVVDVPD 640
+V S +V+ D
Sbjct: 6223 NVKSAANLIVEEED 6236
Score = 123 bits (309), Expect = 9e-28
Identities = 99/374 (26%), Positives = 159/374 (42%), Gaps = 25/374 (6%)
Query: 250 VEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGK 309
V+ K+ FT++L ++ E S+P + +KW+K+G E+ KY + K
Sbjct: 2122 VQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRK 2181
Query: 310 KRILTINKCTLADDAAYE-VAVKDE--KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366
L+I +D Y V V+DE K +L V+ V V L+D +V E+
Sbjct: 2182 VHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELE 2241
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
VS E + W + VEL +Y R L DV +ED+G Y + +G
Sbjct: 2242 CIVSPENIEGKWYHNDVELKSN----GKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2297
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
+ +L ++ + + +LQ ++D V + + +VS E V G W K+G EV+PS R+ I
Sbjct: 2298 KTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI 2357
Query: 487 SHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCS 546
+ H L+I+D+ ED G+Y+F LS S +++ + V
Sbjct: 2358 VIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV---------------- 2401
Query: 547 GKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIE 606
T + V+ G K L+ ++ W DE + I K VI
Sbjct: 2402 -ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK-QRLVIN 2459
Query: 607 SAQREDEGRYTIKV 620
DEG Y + V
Sbjct: 2460 RTHASDEGPYKLIV 2473
Score = 121 bits (303), Expect = 4e-27
Identities = 99/330 (30%), Positives = 138/330 (41%), Gaps = 46/330 (13%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR------------------- 593
++ V G+++ LD SI+G P P TW+K + V E + R
Sbjct: 8191 SLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFV 8250
Query: 594 --IEKRVDC-------SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP-- 642
+ +R+ S + + R D G Y IKV N G A + V+D P PP
Sbjct: 8251 LPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN 8310
Query: 643 ---EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER--KKKGSQRWMKLNFEVFTETT 697
E +R TSV + WEPP+ DGG + Y +E+ K K W+ +
Sbjct: 8311 FVFEDIRKTSV-----LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT-STLRHCK 8364
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTT 754
Y TK+IEG Y RV A N G P + +KP + P P P IVEDVT +
Sbjct: 8365 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8423
Query: 755 LKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGV 814
+KW P G+ I GY +E S W N + V L G +FRV
Sbjct: 8424 VKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAE 8482
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPR 844
N AG + + + P T + PP +PR
Sbjct: 8483 NAAGPGKFSPPSDPKTAHDPISPPGPPIPR 8512
Score = 120 bits (302), Expect = 6e-27
Identities = 88/295 (29%), Positives = 136/295 (46%), Gaps = 15/295 (5%)
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
AG ++L I+G+P P W K D+ T +E D +S +I+ A R + G Y
Sbjct: 20389 AGTSVKLRAGISGKPAPTIEWYKDDKELQTN-ALVCVENTTDLASILIKDADRLNSGCYE 20447
Query: 618 IKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVE 676
+K+ N +G A+I +Q++D P PP + +V + L+W PP DGG +T Y+VE
Sbjct: 20448 LKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE 20507
Query: 677 RKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP-----SMNTKPF 731
+++ W ++ E E +TK+I+G Y RV AVN G+ +P + F
Sbjct: 20508 KRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAF 20566
Query: 732 MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
+ P P V +T + T+ W P G I GY +E + S W E +
Sbjct: 20567 VTPGPPGIP---EVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 20623
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGR---SEPATLAQPVTIREIAEPP-KIRL 842
V L + +RV VN AG+ SEP+ + + PP KIR+
Sbjct: 20624 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRI 20678
Score = 120 bits (300), Expect = 1e-26
Identities = 87/326 (26%), Positives = 140/326 (42%), Gaps = 29/326 (8%)
Query: 523 LNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGD 582
L+ + K +VP P ++ + +G+ A AG+KLR +T
Sbjct: 23243 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT------------- 23289
Query: 583 EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
+E + I D G YT+++ N G +I + ++D P PP
Sbjct: 23290 -----------VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPP 23338
Query: 643 EA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
++I + + WEPP DGG P++GY+VE++ W+ ++ E T +T++ T
Sbjct: 23339 TGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVS-ESVTRSTFKFT 23397
Query: 702 KMIEGILYEMRVFAVNAIGVSQ--PSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRP 759
++ EG Y RV A N G+ S + I P L + DV+ TL W P
Sbjct: 23398 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23457
Query: 760 PNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGR 819
P G + GY+VE ++ WV N PV + L G RV +N G
Sbjct: 23458 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23517
Query: 820 SEPATLAQPVTIRE-IAEPPKIRLPR 844
+P+ ++P+ + IA P K + PR
Sbjct: 23518 GKPSRPSKPIVAMDPIAPPGKPQNPR 23543
Score = 117 bits (294), Expect = 5e-26
Identities = 129/529 (24%), Positives = 197/529 (37%), Gaps = 82/529 (15%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
V +P PP +I G+ + W P++DGG P+TGY VE KK W K + +
Sbjct: 19584 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRG 19642
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLH---------LIVE 746
T Y + + G Y RV +VN +G S PS ++ P + EPL LIV+
Sbjct: 19643 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19702
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+ +R G V L W +T+ R + T
Sbjct: 19703 AGASFTMTVPFR-----------GRPVPNVL-----WSKPDTDLRTRAYVDTTDSRTSLT 19746
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
I A R++ +TI+ + + L + T G N+ V
Sbjct: 19747 I-------ENANRNDSGKYT--LTIQNVLSAASLTLVVKVLDT----PGPPTNITVQDVT 19793
Query: 867 KPRPQVVW----TKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT 922
K + W GGAP+ + R + V LS ++ N+++
Sbjct: 19794 KESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCN------RLSYKVTNLQEG 19847
Query: 923 ATIRIRV--------------------VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
A RV EK PP + V + + + W P+ DG S
Sbjct: 19848 AIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGS 19907
Query: 963 EIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
I+ Y V+ +K W + T VS L +EY+FRV+ EN GLSD
Sbjct: 19908 RIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEYFFRVFAENQAGLSDP----- 19961
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+L + + E E D + P V AG + ++ + G P PKV
Sbjct: 19962 --RELLLPVLIKEQLEPPEIDMKNFPSHTV-----YVRAGSNLKVDIPISGKPLPKVTLS 20014
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALA 1131
++ + ++ +F LT+N++ DAG Y A N G A
Sbjct: 20015 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 20063
Score = 117 bits (293), Expect = 6e-26
Identities = 120/486 (24%), Positives = 203/486 (41%), Gaps = 48/486 (9%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E+S ++ W KNG EI+ S K+ GK L I + D A Y +++
Sbjct: 2858 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSAT 2917
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
L V P++I + L+D D + V V+ EG W+K+GVE+ D K + R K
Sbjct: 2918 LTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTD--KCQMRTK 2973
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
K H L +V D Y + A L VE + +E + I D+ V ++A+F
Sbjct: 2974 K--LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3031
Query: 459 KCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALS 518
+CEVS+ +T +W K+ E++ + RI I H+L+I R D G YT V G +
Sbjct: 3032 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVST 3091
Query: 519 LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW 578
+ ++++ + K+E I + A+V N+ +D A W
Sbjct: 3092 AKLFVEGRDVRIRSI-KKEVQVIE-------KQRAVVEFEVNEDDVD----------AHW 3133
Query: 579 LK-GDEVFTTTEGRTR--IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
K G E+ + R + +E+R+ I ++ D G YT G + +S+ L
Sbjct: 3134 YKDGIEINFQVQERHKYVVERRI--HRMFISETRQSDAGEYTF----VAGRNRSSVTL-Y 3186
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNFEVFT 694
V+ P+PP+ ++ +P GKP ++ + + W K E
Sbjct: 3187 VNAPEPPQVLQ-----------ELQPVTVQSGKPARFCAVISGRPQPKISWYK--EEQLL 3233
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTT 754
T ++ + +G Y + + + + K +A TS L + V +V
Sbjct: 3234 STGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Query: 755 LKWRPP 760
+ PP
Sbjct: 3294 MPVYPP 3299
Score = 117 bits (293), Expect = 6e-26
Identities = 130/526 (24%), Positives = 205/526 (38%), Gaps = 68/526 (12%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF--EVFTET 696
P PEA+ T D L W+PP +DGG + GY+VE +K G + W + N E ET
Sbjct: 10619 PVNPEAIDTTCNSVD---LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPET 10675
Query: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLK 756
Y+ T + +G Y+ RV AVNA G S P+ +P + + EP LI++ +K
Sbjct: 10676 KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIK 10734
Query: 757 WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR------ 810
R+ A +++ W + + + V P G+++ R
Sbjct: 10735 VGDTLRLSA------IIKGVPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHED 10786
Query: 811 --VVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF---- 864
+ + + + T++ V + + PP R L + IRK L P
Sbjct: 10787 GGIYSLTVENPAGSKTVSVKVLVLDKPGPP-----RDLEVSEIRKDSCYLTWKEPLDDGG 10841
Query: 865 --------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQI 916
+ + W+ A + + + R AA + G +
Sbjct: 10842 SVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPF---V 10898
Query: 917 ENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKT 976
E K + + GPP ++ +V T + W P DG S I GY V+ ++ T
Sbjct: 10899 ETPKPIKALD--PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT 10956
Query: 977 MEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
+W ++ + C V+ L G Y FRV ENI GL G+ T P
Sbjct: 10957 QDWIK-FKTVTNLECVVTGLQQGKTYRFRVKAENIVGL----GLPDTTI----------P 11001
Query: 1037 FEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
E +E + + LI+ +VV AG + +RG P P W + EI+ D +
Sbjct: 11002 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11061
Query: 1096 I--TNYQGVLTLN--IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ N+ VLT+ +RR D G Y N G L V
Sbjct: 11062 VETDNFSSVLTIKNCLRR----DTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 117 bits (293), Expect = 6e-26
Identities = 82/297 (27%), Positives = 135/297 (45%), Gaps = 18/297 (6%)
Query: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
+ +++ +G LR+ + G P P TW K D V I + +S + A R+
Sbjct: 21469 DGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGSTSLFVRDATRD 21527
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPV 670
G YT++ N G A I ++V D P +R T++ + L W+ P+ DG P+
Sbjct: 21528 HRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPI 21587
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
T Y++E+++ W + + + +Y + K+I G Y+ RV AVN GV +P +++ P
Sbjct: 21588 THYIIEKRETSRLAWALIEDKCEAQ-SYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDP 21645
Query: 731 F-------MPIAP-TSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+P AP EP ++T + TL W P G I Y++E + S
Sbjct: 21646 VVAQIQYTVPDAPGIPEP-----SNITGNSITLTWARPESDGGSEIQQYILERREKKSTR 21700
Query: 783 WVPA-NTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
WV + P+ F V L G F V+ N AG + +++ + RE PP
Sbjct: 21701 WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 21757
Score = 117 bits (292), Expect = 8e-26
Identities = 112/425 (26%), Positives = 166/425 (39%), Gaps = 46/425 (10%)
Query: 729 KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANT 788
KP +P P ++VT TLKW PP G I Y++E + +WV
Sbjct: 13578 KPGIPTGPIK------FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC-A 13630
Query: 789 EPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPVTIREIAEPPKIRLP 843
V++ F V L G FRV N G +SEP P + + PP I
Sbjct: 13631 SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDV 13690
Query: 844 RH----LRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFV 899
RH L T +K G + K R ++W + ++ +R DF
Sbjct: 13691 RHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA------NKTPIRMRDF------ 13738
Query: 900 RQAARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
+ ++ EYE V N+ + + ++ PP V + + + W
Sbjct: 13739 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWT 13798
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
PK DG ++ GY V+K D + W N + TV+DL+ G +Y FR+ +N G
Sbjct: 13799 EPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAG 13858
Query: 1014 LSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC-AVR 1072
+P S T I K EY+ + P L + AG + LN ++
Sbjct: 13859 AISAPSESTETI-ICKD-------EYEAPTIVLDPTIKDGL---TIKAGDTIVLNAISIL 13907
Query: 1073 GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAE 1132
G P PK W K +IR IT+ L I+ + DAG YT A N G +
Sbjct: 13908 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 13967
Query: 1133 CKLEV 1137
K+ V
Sbjct: 13968 VKVTV 13972
Score = 115 bits (287), Expect = 3e-25
Identities = 132/509 (25%), Positives = 215/509 (42%), Gaps = 64/509 (12%)
Query: 159 DASGQSLESFKRTSEK---KSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIW 215
+ S + FKR +E+ ++ TA EL +K++ EE +K KD E+
Sbjct: 1946 EESEELRSKFKRRTEEGYYEAITAVELKS----RKKDESYEELLRKTKD--------ELL 1993
Query: 216 ELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLD--PAYQVDRGNK 273
K + E + +A + IT + K K+E+ S K + + V +G+
Sbjct: 1994 HWTKELTEEEKKALAEEGKIT-----IPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSD 2048
Query: 274 IKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVF----ENVGKKRILTINKCTLADDAAYEV 328
V + PD +W+KNG +I+ S + + +NV + L I T D A+ V
Sbjct: 2049 AHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE---LVIRDVTAEDSASIMV 2105
Query: 329 A---VKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAV---EVSEEGAQVMWMKDG 382
+ E + + LI E Q V ++ MA E SE +V W KDG
Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2165
Query: 383 VELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI---TNGGQCEAELIVEEKQL 439
+E+ D +YR D K H L + D Y + + A+LIVE +
Sbjct: 2166 MEVHEGD----KYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVV 2221
Query: 440 EVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
E ++++ D+ V S +C VS E + GKWY N VE++ + + TI+ L + D
Sbjct: 2222 EFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKD 2281
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V ED+G+Y+FV DG + K+ K P I S + V G
Sbjct: 2282 VTKEDQGEYSFVIDGKKTTCKLKM-----------KPRPIAILQGLSDQK------VCEG 2324
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+ ++L+V ++ E W+K G EV + I+K+ +IE +ED G Y+
Sbjct: 2325 DIVQLEVKVSLESVE-GVWMKDGQEVQPSDRVHIVIDKQ--SHMLLIEDMTKEDAGNYSF 2381
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ + + VDV P + V +
Sbjct: 2382 TIPALGLSTSGRVSVYSVDVITPLKDVNV 2410
Score = 114 bits (286), Expect = 4e-25
Identities = 137/562 (24%), Positives = 213/562 (37%), Gaps = 62/562 (11%)
Query: 586 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE-DVASIFLQVVDV---PDP 641
T T+ R R+ + S+ A G VGE S+F + D P P
Sbjct: 18458 TLTDLRLRVTGLTEGHSYEFRVAAENAAG---------VGEPSEPSVFYRACDALYPPGP 18508
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE-TTYES 700
P ++T L W P+YDGG PV GY+VE K+ + W + +
Sbjct: 18509 PSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18568
Query: 701 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTS-EP--------LHLIVEDVTDT 751
TK+ E Y R+ A+N+ GV +P+ T P +A EP L +V
Sbjct: 18569 TKLKENTEYNFRICAINSEGVGEPA--TLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18626
Query: 752 T----TTLKWRPPNRIGAGGIDGYLVEYC-LEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
T T+K RP + +G L + +E + + + V R NL
Sbjct: 18627 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 18686
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ VN+ P+ +TIRE+ K + I + N +V +
Sbjct: 18687 SGSKTAFVNVRVLDSPSAPVN-LTIREVK---KDSVTLSWEPPLIDGGAKITNYIVEKRE 18742
Query: 867 KPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR 926
R T R+ F V S EY + + E T
Sbjct: 18743 TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA-----SNEYGIGLPAET-----TEP 18792
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++V E PP V + +V A ++W+ P+ DG S+I GY V+ K + +W + +
Sbjct: 18793 VKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKW-STCTQV 18851
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKP-FEYKEHDFR 1045
+ T+S L G EY FRV N G SD + ++ I KP E H F
Sbjct: 18852 KTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG---VPVIARDIEIKPSVELPFHTFN 18908
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
V A ++ +G P+ V W K+ ++E + +++ + V +L
Sbjct: 18909 -------------VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 18955
Query: 1106 NIRRPSPFDAGTYTCRAVNELG 1127
+I+ S D GTY N G
Sbjct: 18956 SIKEASKEDVGTYELCVSNSAG 18977
Score = 111 bits (277), Expect = 4e-24
Identities = 74/266 (27%), Positives = 120/266 (45%), Gaps = 9/266 (3%)
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFE 305
K ++K A KK V VE++ P++ ++W KNG ++ + KY
Sbjct: 2651 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2710
Query: 306 NVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEM 365
G L I C + D++ Y + L V+ V I+ +D V
Sbjct: 2711 VKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVET--VKIIKKPKDVTALENATVAF 2768
Query: 366 AVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNG 425
V VS + V W VE+ D ++R + K H L+ ++ D G Y +
Sbjct: 2769 EVSVSHDTVPVKWFHKSVEIKPSD----KHRLVSERKVHKLMLQNISPSDAGEYTAVVGQ 2824
Query: 426 GQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRIT 485
+C+A+L VE L + + + ++ V ++ A F+CEVS V W KNGVE+ S++
Sbjct: 2825 LECKAKLFVET--LHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFK 2882
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFV 511
I G+ H+L+I + ED +YTFV
Sbjct: 2883 IVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Score = 108 bits (271), Expect = 2e-23
Identities = 107/416 (25%), Positives = 166/416 (39%), Gaps = 37/416 (8%)
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
+P S L +D+ + + WRPP G I GY++E W ++ V
Sbjct: 23730 SPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGT 23788
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK--IRLPRHLRQT--- 849
VK L FRV N G S+P +PVT + PP+ P L T
Sbjct: 23789 SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSS 23848
Query: 850 ----YIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDF-DTVFFVRQA 902
+ R + + V + + K W + T+ ++ T D + R
Sbjct: 23849 VSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRII 23908
Query: 903 ARSDSGEYELSVQIENM--KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDG 960
A++D G E S E + KD +K P + + + + ++W+ P+ DG
Sbjct: 23909 AQNDVGLSETSPASEPVVCKDP-------FDKPSQPGELEILSISKDSVTLQWEKPECDG 23961
Query: 961 NSEIMGYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
EI+GY+V+ W ER + T+ L+ EY FRV+ EN GLS
Sbjct: 23962 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP-- 24019
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKV 1079
+ TA +KT +T AP + D G +A L+C + G P P +
Sbjct: 24020 --RRTAMSIKTKLTSGE----------APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 24067
Query: 1080 VWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
W + E+ + K+ +++ TL + D G YTC A NE+GE KL
Sbjct: 24068 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123
Score = 107 bits (266), Expect = 8e-23
Identities = 121/519 (23%), Positives = 189/519 (36%), Gaps = 75/519 (14%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF-EVFTETT 697
P PP ++ L W P YDGG P+ GYLVE K+ S W++ N + +T
Sbjct: 13092 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13151
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT----- 752
+E T ++E Y+ RV+AVN IG S PS P P + D+ T
Sbjct: 13152 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13211
Query: 753 ------TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RPP +I W N +R G +K+
Sbjct: 13212 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKSTDFDTF 13253
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQG 866
+ V AG+ TL +E K+ + G +N+ V
Sbjct: 13254 LRCENVNKYDAGKYI-LTLENSCGKKEYTIVVKV----------LDTPGPPVNVTVKEIS 13302
Query: 867 KPRPQVVWTK----GGAPLDTSRVHVRTSDFDTVFFV---------RQAARSDSGEYELS 913
K V W GG+P+ V R ++ + V R A + Y
Sbjct: 13303 KDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFR 13362
Query: 914 VQIEN---MKDTATIR--IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V EN + D R ++ + GP +++ V+ V ++ + W+ P DG S I+GY
Sbjct: 13363 VFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYV 13422
Query: 969 VQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
V ++ +W V ++ + DL G EY FRV EN + G +
Sbjct: 13423 VDFLTEEN-KWQRVM-KSLSLQYSAKDLTEGKEYTFRVSAEN----ENGEGTPSEITVVA 13476
Query: 1029 KTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI 1088
+ + + K P + + + L ++G P P V W K + +
Sbjct: 13477 RDDVVAPDLDLKG----------LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPL 13526
Query: 1089 REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
D + + + TL + DAG YT N G
Sbjct: 13527 ATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 13565
Score = 107 bits (266), Expect = 8e-23
Identities = 108/487 (22%), Positives = 190/487 (39%), Gaps = 42/487 (8%)
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTET-TYESTKMIEGILYEMRVFAVNAIGVSQPS 725
GKP+ + R + M+ N E+ E T + + + A N+ G ++
Sbjct: 20005 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20064
Query: 726 MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVP 785
+N P + P+ ++ D+T+ + TLKW PP G + Y++ + W
Sbjct: 20065 INIVVLDRPGPPTGPV--VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20122
Query: 786 ANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRL 842
+ V R V L TG FR+ N G S+ A VT++ PP
Sbjct: 20123 VSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSAC-VTVKLPYTTPGPPSTPW 20180
Query: 843 PRHLRQTYI-----RKVGEQLNLVVPF--QGKPRPQVVWTKGGA-PLDTSRVHVRTSDFD 894
++ + I V + VV + + K R ++W K + T+ V T
Sbjct: 20181 VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAG 20240
Query: 895 TVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQ 954
++ R A + +G + S E + ++ PP NV + ++ + + WQ
Sbjct: 20241 LIYEFRVYAENAAGVGKPSHPSEP--------VLAIDACEPPRNVRITDISKNSVSLSWQ 20292
Query: 955 APKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG 1013
P DG S+I GY V++ D W N T +S L ++Y FRV+ N G
Sbjct: 20293 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 20352
Query: 1014 LSDSPGVSKNTARILKT---GITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
+P + + + P EY E K+ AG S L
Sbjct: 20353 SISNPSEVVGPITCIDSYGGPVIDLPLEYTE-----VVKYR---------AGTSVKLRAG 20398
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
+ G P P + W K+ E++ + + N + ++ I+ ++G Y + N +G A
Sbjct: 20399 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 20458
Query: 1131 AECKLEV 1137
A ++++
Sbjct: 20459 ATIRVQI 20465
Score = 106 bits (265), Expect = 1e-22
Identities = 114/409 (27%), Positives = 180/409 (44%), Gaps = 52/409 (12%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
EIS+ D+ +W G+ ++PS + G KR LT++K L D A EV + T
Sbjct: 4922 EISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKL--DQAGEVLYQALNAITT 4979
Query: 339 --LFVKEPPVLIVTPLEDQQVFVGDRVEMAVE-VSEEGAQVMWMKDGVELTREDSFKARY 395
L VKE + PL+D V V +R + E V A V+W K + D F
Sbjct: 4980 AILTVKEIELDFAVPLKD--VTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFD--- 5034
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQ 455
DGK+HIL+ +D +D G Y G + A L V +L+ + + D TVK E
Sbjct: 5035 -IIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGET 5093
Query: 456 AVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
A F CE+S EK+ W+KN ++ S+ + IS G+ HKL + +V +D
Sbjct: 5094 ATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQ--IKAQVK 5151
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV 575
LS +A+L LE P + KT+ V +++ L ++ + P
Sbjct: 5152 ELSSTAQLKVLE---------ADPYFTVKLHDKTA------VEKDEITLKCEVSKDVP-- 5194
Query: 576 ATWLK-GDEVFTT------TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 628
W K G+E+ + +G RI K I+ A +D+G Y +
Sbjct: 5195 VKWFKDGEEIVPSPKYSIKADGLRRILK--------IKKADLKDKGEYVCDCGTDKTKAN 5246
Query: 629 ASIFLQVVDVPDPPEAVRITSVGE--DWAILVWEPPMYD----GGKPVT 671
++ +++ V P V + VGE + I + EP ++ G+P+T
Sbjct: 5247 VTVEARLIKVEKPLYGVEV-FVGETAHFEIELSEPDVHGQWKLKGQPLT 5294
Score = 104 bits (259), Expect = 5e-22
Identities = 98/393 (24%), Positives = 166/393 (42%), Gaps = 39/393 (9%)
Query: 243 KRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKY 302
K +K KV KK A F E+S+PD+T++W K+ QE++ + +
Sbjct: 3016 KHIKDIKVLEKKRAMFE------------------CEVSEPDITVQWMKDDQELQITDRI 3057
Query: 303 VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDR 362
+ L I ++D Y V +LFV+ V I + ++ QV R
Sbjct: 3058 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3117
Query: 363 VEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI 422
+ EV+E+ W KDG+E+ + + R+++ + + H + S+ Q D G Y +
Sbjct: 3118 AVVEFEVNEDDVDAHWYKDGIEINFQ--VQERHKYVVERRIHRMFISETRQSDAGEYTFV 3175
Query: 423 TNGGQCEAELIVEEKQL-EVLQDIADLTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVR 479
+ L V + +VLQ++ +TV++ + A F C V + K WYK +
Sbjct: 3176 AGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLS 3234
Query: 480 PSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVPKQE- 537
+ H G+ + L++ + PED YT + Y ++ ++ +E+ P QE
Sbjct: 3235 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEM 3294
Query: 538 ---PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGR-TR 593
PP I T V G R ++G V+ + K ++ + R T+
Sbjct: 3295 PVYPPAII------TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQ 3348
Query: 594 IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
E D I A EDEG YT +N VG+
Sbjct: 3349 FE---DTYQLEIAEAYPEDEGTYTFVASNAVGQ 3378
Score = 103 bits (256), Expect = 1e-21
Identities = 109/405 (26%), Positives = 177/405 (43%), Gaps = 35/405 (8%)
Query: 249 KVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVG 308
KV+V + AA ++ G K + + IS ++W ++ + ++ KY G
Sbjct: 6047 KVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADG 6106
Query: 309 KKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVE 368
KKR+L + TL D Y V V + L V E + IV PL+D +V V E
Sbjct: 6107 KKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCE 6165
Query: 369 VSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV-ITN--- 424
V+ EGA+ W ++ E DS ++Y + + L D +D+ Y V +TN
Sbjct: 6166 VNTEGAKAKWFRN--EEAIFDS--SKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6221
Query: 425 -GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKR 483
+ A LIVEE+ L +++ + D+ + F C+V+ VT KW KNG EV R
Sbjct: 6222 ENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNR 6281
Query: 484 ITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHL 543
++ H L I D DEG+Y V G S+ A+L +E E+V HL
Sbjct: 6282 VSYRVDKYKHMLTIKDCGFPDEGEY-IVTAGQDKSV-AELLIIEAPTEFVE-------HL 6332
Query: 544 DCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT-RIEKRVDCSS 602
+ T + V ++ E V + G E+ EG+ + EK
Sbjct: 6333 EDQTVTEFDDAV--------FSCQLSREKANVKWYRNGREI---KEGKKYKFEKDGSIHR 6381
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQ--VVDVPDPPEAV 645
+I+ + +DE Y V + + A +F++ V++ PP+ +
Sbjct: 6382 LIIKDCRLDDECEYACGVED--RKSRARLFVEEIPVEIIRPPQDI 6424
Score = 102 bits (254), Expect = 2e-21
Identities = 114/516 (22%), Positives = 191/516 (37%), Gaps = 76/516 (14%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
+D P PP +RI + L W P+YDGG VTGY+VE ++ + W ++ +
Sbjct: 20667 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20726
Query: 696 TT-YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMP-------------------IA 735
TT Y + + G+ Y RV AVN G +P +P IA
Sbjct: 20727 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIA 20786
Query: 736 PTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERC 794
E + +++ T+ WR + G Y +E S +P T +
Sbjct: 20787 KAGEDVQVLIPFKGRPPPTVTWRKDEK-NLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20845
Query: 795 GFTVKN---LPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
T++N P + + +V+ A + T+ + +PP I + I
Sbjct: 20846 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYE 911
K + + W+ ++ + T FF R A ++ G E
Sbjct: 20906 EK-------------RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGE 20952
Query: 912 LSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
E +K E P ++ +K+ T+ ++ W P DG S I Y V++
Sbjct: 20953 PCETTEPVK--------AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVER 21004
Query: 972 ADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTG 1031
K W + ++ VS L + FRV+ +N GLSD
Sbjct: 21005 KGKGEQTWSHA-GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-------------- 21049
Query: 1032 ITFKPFEYKEHDFRMAPKFLTPLIDR--------VVVAGYSAALNCAVRGHPKPKVVWMK 1083
+T P KE +TP +D V G++ L +G PKP + W+K
Sbjct: 21050 VTIGPITVKE-------LIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLK 21102
Query: 1084 NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1119
+ + ++E + + +TL+I+ G YT
Sbjct: 21103 DGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21138
Score = 99.8 bits (247), Expect = 1e-20
Identities = 71/264 (26%), Positives = 127/264 (48%), Gaps = 11/264 (4%)
Query: 268 VDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K L ++S PD+T +KW+ N ++IKP + G K+ L IN+ +D+ Y
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2469
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMW-MKDGVEL 385
++ V + L V++ + I+ L D V VE+S G V+W KD
Sbjct: 2470 KLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKD---- 2523
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+E ++Y+ + GK + L +++++D G+Y +L V + + +
Sbjct: 2524 -KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPL 2580
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
D TV S++AVF+CEV++ G+W ++G + + I G +L+I + +D
Sbjct: 2581 TDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDI 2640
Query: 506 GDYTFVPDGYALSLSAKLNFLEIK 529
G+YT+ S K+ ++IK
Sbjct: 2641 GEYTYKVATSKTSAKLKVEAVKIK 2664
Score = 99.0 bits (245), Expect = 2e-20
Identities = 109/513 (21%), Positives = 188/513 (36%), Gaps = 49/513 (9%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV-FTETT 697
P PP ++ + L W P+YDGG + GY+VE+ W +T
Sbjct: 16341 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 16400
Query: 698 YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP---LHLIVEDVTDTTT- 753
E K++E Y R+ A+N GV + + P + P L L + + +
Sbjct: 16401 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 16460
Query: 754 -------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
+K RP + G +DG + + + + + V +G
Sbjct: 16461 GSLRLFVPIKGRPTPEVKWGKVDGEIRDAAI------IDVTSSFTSLVLDNVNRYDSGKY 16514
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF-Q 865
L + T + VT+R + P P +L+ T I K + P
Sbjct: 16515 TLTL--------ENSSGTKSAFVTVRVLDTPSP---PVNLKVTEITKDSVSITWEPPLLD 16563
Query: 866 GKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE---NMKDT 922
G + + + S V T+ + + Q S + ++ + E +
Sbjct: 16564 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16623
Query: 923 ATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV 982
I+V E PP + V +V + + W P+ DG S+I+ Y V+ K + +W
Sbjct: 16624 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16683
Query: 983 YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
R + +++L G EY FRV N G SD R L I K
Sbjct: 16684 -ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP--------RSLAVPIVAK------- 16727
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P V G + + G PKP + W K+ + +++ + +T+ +
Sbjct: 16728 DLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDL 16787
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
TL+I+ D G Y N +G+ A ++
Sbjct: 16788 TTLSIKETHKDDGGQYGITVANVVGQKTASIEI 16820
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/541 (23%), Positives = 199/541 (36%), Gaps = 74/541 (13%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTY 698
P PP + + L W+PP DGG P+ GY+VE +++G+ W ++N TT
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9267
Query: 699 EST--KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT--- 753
E + E Y RV AVN G S+PS T EP I D
Sbjct: 9268 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9327
Query: 754 --------TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGA 805
+K RP + + DG + +G + +P + + +V +P
Sbjct: 9328 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 9385
Query: 806 RILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-- 863
R + ++ T V + ++ PPK L+ + I + +L+ +P
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 9440
Query: 864 ----------FQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + WTK ++ V + +F R A + G +
Sbjct: 9441 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG---IG 9497
Query: 914 VQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--- 970
+E ++ T T R + PPI + + + + W+ PK+DG S + Y V+
Sbjct: 9498 PPVETIQRT-TARDPIYPP-DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 9555
Query: 971 --KADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
K W +R+ TV DL+ G EY FRV N G+S
Sbjct: 9556 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVS------------ 9603
Query: 1028 LKTGITFKPFEYKEHDFRMAPKFLTPLID----RVVVAGYSAALNCAVRGHPKPKVVWMK 1083
K T P + + D + P ID V G + + ++G P P + W K
Sbjct: 9604 -KPSATVGPCDCQRPD-------MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9655
Query: 1084 -------NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
NK + D TL I + D G YT AVN LG A E +L
Sbjct: 9656 APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLN 9715
Query: 1137 V 1137
V
Sbjct: 9716 V 9716
Score = 97.4 bits (241), Expect = 7e-20
Identities = 101/436 (23%), Positives = 166/436 (38%), Gaps = 41/436 (9%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N+ G + ++N P + P+ + ++VT + TL W PP G I+ Y+VE
Sbjct: 15727 NSAGEAIETLNVIVLDKPGPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKR 15784
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRS-----EPATLAQPVTI 831
+ W + V R L TG FR+ N G+S EP P +
Sbjct: 15785 DTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 15843
Query: 832 REIAEPPKIRLPRH--LRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVH 887
P + L + + + + + V+ + + K R ++W K ++
Sbjct: 15844 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVK------LNKTP 15897
Query: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENM----KDTATIRIRVV-EKAGPPINVMVK 942
+ + F T + EYE V EN+ K + V + PP
Sbjct: 15898 IPQTKFKTT------GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAI 15951
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR-HTSCTVSDLIVGNE 1001
V + ++W+ P DG S+I GY V+K + W N T V+ L+ +
Sbjct: 15952 IVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHR 16011
Query: 1002 YYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVA 1061
Y FRV N G+ P S TG E M PK+ + VV A
Sbjct: 16012 YEFRVIARNAAGVFSEPSES--------TGAITARDEVDPPRISMDPKYKDTI---VVHA 16060
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
G S ++ + G P P + W+K E+ + I + +L+++ D+G Y +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 1122 AVNELGEALAECKLEV 1137
A N GE ++V
Sbjct: 16121 AKNVAGERSVTVNVKV 16136
Score = 95.5 bits (236), Expect = 3e-19
Identities = 116/453 (25%), Positives = 166/453 (36%), Gaps = 51/453 (11%)
Query: 694 TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTT 753
T + + T +G Y + V N +G S+ P P+ +DV+ +
Sbjct: 16788 TTLSIKETHKDDGGQYGITV--ANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESI 16843
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813
TL W PP G I Y+V+ + W + V R V L TG FR+
Sbjct: 16844 TLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFA 16902
Query: 814 VNIAGRS---EPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLN------LVVPF 864
N G+S E + +E P + + + + E +N +
Sbjct: 16903 ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 16962
Query: 865 QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM---- 919
+ K R ++WTK ++ + +H DT F +A + G EYE V EN+
Sbjct: 16963 ERKERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVG 17009
Query: 920 ----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
+ + G P +MVK ++W P DG S I GY V+K D
Sbjct: 17010 KASKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLP 17066
Query: 976 TMEWFNVYERNR-HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF 1034
W N T TVS L Y FRV +N G P S TG
Sbjct: 17067 DGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDS--------TGPIT 17118
Query: 1035 KPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF 1094
E + M PKF + VV AG + L V G P P + W++ EI E +
Sbjct: 17119 AKDEVELPRISMDPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARC 17175
Query: 1095 LITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
I N L ++ D G Y RA N G
Sbjct: 17176 EIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 17208
Score = 94.4 bits (233), Expect = 6e-19
Identities = 72/213 (33%), Positives = 98/213 (46%), Gaps = 16/213 (7%)
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHT 989
EK G P + V + +V W+ P DG ++I Y+++K +KK +W +V E R T
Sbjct: 24326 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24385
Query: 990 SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK 1049
+V +LI G EY FRV EN+ G S+ +S +P K AP
Sbjct: 24386 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-------------EPITPKSDVPIQAPH 24432
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP-KFLITNYQ-GVLTLNI 1107
F L + V +A L C V GHPKP V W + EI D K+ I ++ G L I
Sbjct: 24433 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 24492
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
+ DA Y RA N+ G LEV VP
Sbjct: 24493 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24525
Score = 94.0 bits (232), Expect = 7e-19
Identities = 95/391 (24%), Positives = 171/391 (43%), Gaps = 37/391 (9%)
Query: 240 GMLKRLKKAKVEVKK-SAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQ-EIK 297
G ++ AK+ V++ F K L+ V +G + L E++ + + W K+G+ ++
Sbjct: 4698 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVE 4756
Query: 298 PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFT-ELFVKEPPVL---IVTPLE 353
+ V +G R LTIN D Y V V++ VK V+ +V P+
Sbjct: 4757 KPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIR 4816
Query: 354 DQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQ 413
DQ V A +++++ + W K E+ E + K +DG L + +
Sbjct: 4817 DQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTE--ILRDGNHLYLKIKNAMP 4874
Query: 414 EDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYK 473
ED Y V G + A+L + E+++E+L+ I D+T+ E A F E+S+ + G+W
Sbjct: 4875 EDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKL 4934
Query: 474 NGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEY- 532
G +RPS I G L + V+ + G+ + +A L EI++++
Sbjct: 4935 KGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLY--QALNAITTAILTVKEIELDFA 4992
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
VP ++ + V + R + +T E + W KG ++ +++
Sbjct: 4993 VPLKD----------------VTVPERRQARFECVLTREANVI--WSKGPDIIKSSDKFD 5034
Query: 593 RI---EKRVDCSSFVIESAQREDEGRYTIKV 620
I +K + VI +Q +DEG YT +V
Sbjct: 5035 IIADGKKHI----LVINDSQFDDEGVYTAEV 5061
Score = 92.8 bits (229), Expect = 2e-18
Identities = 113/454 (24%), Positives = 174/454 (38%), Gaps = 76/454 (16%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
NA G S+ K P + L V VT TL W P G I Y+VE
Sbjct: 22627 NASGTKAVSVMVKVLDSPGPCGK---LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERR 22683
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE--- 833
WV E + V L +FRV VN G P ++P+ R
Sbjct: 22684 ETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFT 22741
Query: 834 IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK----GGAPLDTSRVHVR 889
I PP I +VG GK + WTK GG + V R
Sbjct: 22742 IPSPPGIP----------EEVGT---------GKEHIIIQWTKPESDGGNEISNYLVDKR 22782
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE------------------ 931
++ + R D Y+ +++ ++ + + RV
Sbjct: 22783 EKK--SLRWTR--VNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISC 22838
Query: 932 -----KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
GPP V + + + W P DG ++I+GY ++ +K T +W+ V+
Sbjct: 22839 REPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNA 22898
Query: 987 --RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKE-HD 1043
R+T TV DL +G +Y FRV N+ G+S+ S++ A I +P E E D
Sbjct: 22899 TIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSE---YSESIAEI-------EPVERIEIPD 22948
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
+A + R AG S L +V G P P + W K +++ + +I +
Sbjct: 22949 LELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITWSKQGIDLAS--RAIIDTTESYS 23003
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L + + + +DAG YT A N+ G+ A ++V
Sbjct: 23004 LLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23037
Score = 91.7 bits (226), Expect = 4e-18
Identities = 62/245 (25%), Positives = 116/245 (47%), Gaps = 7/245 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G+ ++L V++S + W K+GQE++PS + + +L I T D Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVEL 385
+ T V V ++TPL+D V G + + +VS + V W + ++
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+D +A + G + L+ + D G Y++I + L VE+ +++++ +
Sbjct: 2440 KPDDRVQAIVK----GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEK--IKIIRGL 2493
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
DLT ++ VF+ E+S + W E++PS + I G+ +KL + ++ +DE
Sbjct: 2494 RDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDE 2553
Query: 506 GDYTF 510
G YTF
Sbjct: 2554 GKYTF 2558
Score = 91.3 bits (225), Expect = 5e-18
Identities = 106/430 (24%), Positives = 163/430 (37%), Gaps = 59/430 (13%)
Query: 734 IAPTSEPLHLI-VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE 792
+ P S+P I +++ + L W P G G I Y +E W + V
Sbjct: 21157 LGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VA 21215
Query: 793 RCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIR 852
R F V NL A FRV N G ++QP+ I + R+P + I
Sbjct: 21216 RTTFKVPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPGPPGKPVIY 21269
Query: 853 KV---GEQLNLVVPF------------QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
V G L P + K R ++W K ++TS + R
Sbjct: 21270 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK----VNTSPISGRE------- 21318
Query: 898 FVRQAARSDSGEYELSVQIENMKDTA--------TIRIRVVEKAGPPINVMVKEVWGTNA 949
R + +Y+ V EN + T+ + V+ G P + +V
Sbjct: 21319 -YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETI 21374
Query: 950 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYT 1008
++W P DG S+I+GY ++K W + TV+ L G+ Y FR+
Sbjct: 21375 TLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21433
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALN 1068
N G P S +GI E P++ LI + +G S +
Sbjct: 21434 RNAVGTISPPSQS--------SGIIMTRDENVPPIVEFGPEYFDGLI---IKSGESLRIK 21482
Query: 1069 CAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
V+G P P+V W K+ +EI + IT+ G +L +R + G YT A N G
Sbjct: 21483 ALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGS 21542
Query: 1129 ALAECKLEVR 1138
A AE K++V+
Sbjct: 21543 AKAEIKVKVQ 21552
Score = 90.1 bits (222), Expect = 1e-17
Identities = 105/434 (24%), Positives = 163/434 (37%), Gaps = 37/434 (8%)
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
E ++ NA G +++ P + P++++ DVT T+ W+PP G +
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVI 11140
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPV 829
Y+VE + W ++ + + +L G +FRV N G P V
Sbjct: 11141 NYIVEKQDTRKDTWGVVSSGS-SKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV 11199
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
+ + P P T I + ++ +P P + + V V
Sbjct: 11200 AKHKFSPPSP---PGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11256
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPINVMV 941
+ + F R + YE V EN+ + R ++ GPPIN +
Sbjct: 11257 KTPIADLKF-RVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKL 11315
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEW--FNVYERNRHTSCTVSDLIVG 999
K+ A + W P DG S I+GY V+ T +W N E R + V LI G
Sbjct: 11316 KDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEG 11375
Query: 1000 NEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVV 1059
NEY FR+ NI G + R L + K D P+ + R V
Sbjct: 11376 NEYRFRIKAANIVG--------EGEPRELAESVIAK-------DILHPPEVELDVTCRDV 11420
Query: 1060 VA---GYSAALNCAVRGHPKPKVVWMK-NKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ G + + V+G P+P + W K K+ +RE LI + V L I+ D
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADH 11479
Query: 1116 GTYTCRAVNELGEA 1129
G Y A N G A
Sbjct: 11480 GKYIISAKNSSGHA 11493
Score = 89.4 bits (220), Expect = 2e-17
Identities = 103/435 (23%), Positives = 167/435 (38%), Gaps = 40/435 (9%)
Query: 709 YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
YE+++ NA+G + ++ + P P+ + VT TL WRPP G I
Sbjct: 20446 YELKLR--NAMGSASATIRVQILDKPGPPGGPIEF--KTVTAEKITLLWRPPADDGGAKI 20501
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE W + E +E C T + G +FRV VN G EP
Sbjct: 20502 THYIVEKRETSRVVWSMVS-EHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSV 20560
Query: 829 VTIREIAEPPKIRLPRHLRQT-------YIRKVGEQLNLVVPF--QGKPRPQVVWTKG-G 878
V P +P + T + R + + + + + + + + + W K
Sbjct: 20561 VAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLK 20620
Query: 879 APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPIN 938
+ +R V ++ + R A + +G+ S E K I + GPP
Sbjct: 20621 ETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI-----DPPGPPAK 20675
Query: 939 VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSDL 996
+ + + ++ + W P DG S + GY V+ + EW V + R T VS+L
Sbjct: 20676 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 20735
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G YYFRV N G + +++ P + K D AP+ +
Sbjct: 20736 KPGVNYYFRVSAVNCAGQGEPIEMNE-------------PVQAK--DILEAPEIDLDVAL 20780
Query: 1057 RVVV---AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPF 1113
R V AG + +G P P V W K++ + D ++ I N L I + +
Sbjct: 20781 RTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRN 20840
Query: 1114 DAGTYTCRAVNELGE 1128
D G Y N +GE
Sbjct: 20841 DTGKYILTIENGVGE 20855
Score = 89.4 bits (220), Expect = 2e-17
Identities = 134/655 (20%), Positives = 251/655 (38%), Gaps = 101/655 (15%)
Query: 23 KEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPD 82
K++ K + ++ P+ P + +P V + +V + A K G+
Sbjct: 26328 KKSDQKTTESTVTRKTEPKAPEPISSKP--VIVTGLQDTTVSSDSVAKFAVKATGEP--- 26382
Query: 83 KPTIKWFK-GKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAK 141
+PT W K GK + G K +K S D+G + LE+
Sbjct: 26383 RPTAIWTKDGKAITQGGK------YKLSE-------------------DKGGFFLEIHKT 26417
Query: 142 DTCDSCGFNIDVEAPRQDASGQ---SLESFKRTSEKKSDTAGELDFSGLLKKREVVEEE- 197
DT DS + V+ S ++++ K T +K T + + +K+ VV+EE
Sbjct: 26418 DTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITP--QKKAVVQEEI 26475
Query: 198 ----------KKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKK 247
K + K + L + E ++L + + + + I + + + +
Sbjct: 26476 SQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSI--VHEEITKTSQ 26533
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
A EV+ A K ++ G ++ L I+ +KW NG E+ S +Y +
Sbjct: 26534 ASEEVRTHAEI-KAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNSEEYRYGVS 26591
Query: 308 GKKRILTINKCTLADDAAYEVAVKDE----KCFTELF----VKEPPVLIVTPLEDQQVFV 359
G + LTI + + D+ K + KC +L + + P I P Q +
Sbjct: 26592 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RSQNINE 26650
Query: 360 GDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGR 418
G V E+S E ++ W K+ + + S + + + L + D G+
Sbjct: 26651 GQNVLFTCEISGEPSPEIEWFKNNLPI----SISSNVSISRSRNVYSLEIRNASVSDSGK 26706
Query: 419 YQVITNG--GQCEAEL------IVEEKQLE-VLQDIADLTVKAS------EQAVFKCEVS 463
Y + GQC A +VEE E VL+ D +++ S + + K E S
Sbjct: 26707 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26766
Query: 464 DEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG--DYTFVPDGYALSLSA 521
+ + E++ + ++ + + ++ G + T + + L A
Sbjct: 26767 FSSFSSSSASSMTEMKFAS-MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKA 26825
Query: 522 KLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW-LK 580
+ + K+E +P I + G L + + TGEP P TW
Sbjct: 26826 GIRGIPPKIEALPSD-----------------ISIDEGKVLTVACAFTGEPTPEVTWSCG 26868
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
G ++ + +GR IE D ++ +I Q++D G YT+ + N G D A++ + +
Sbjct: 26869 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 88.2 bits (217), Expect = 4e-17
Identities = 106/434 (24%), Positives = 168/434 (38%), Gaps = 44/434 (10%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ AVN +G + M P P+ E V+ TL W PP G I Y+
Sbjct: 9699 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKF--ESVSADQMTLSWFPPKDDGGSKITNYV 9756
Query: 773 VEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIR 832
+E + WV ++EP E C +T+ L G +FR++ N G EP ++P T R
Sbjct: 9757 IEKREANRKTWVHVSSEPKE-CTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD-SEPETAR 9814
Query: 833 EIAEPPKIRLPRHLRQTYIRKVGEQLNLVVP-FQGKPRPQVVWTKGGAPLDTSRVHVRTS 891
+ P P + + + +N P + G W + DT+ +
Sbjct: 9815 NLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLE---MKDTTSKRWKRV 9869
Query: 892 DFDTVFFV------RQAARSDSGEYELSVQIENM---------KDTATIRIRVVEKAGPP 936
+ D + + + + +Y+ V N D AT R + GPP
Sbjct: 9870 NRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP-GPP 9928
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSD 995
V + ++A +EW P DG S++ GY V+ ++ EW ++ R T V+
Sbjct: 9929 FP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTG 9987
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G Y FRV NI G+ + PG + E K+ + +
Sbjct: 9988 LKEGAFYKFRVRAVNIAGIGE-PGEVTDV------------IEMKDRLVSPDLQLDASVR 10034
Query: 1056 DRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
DR+VV AG + V G P P V W N+ + ++ T ++ I+
Sbjct: 10035 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSH 10092
Query: 1115 AGTYTCRAVNELGE 1128
G Y+ A NE GE
Sbjct: 10093 QGVYSLLAKNEAGE 10106
Score = 88.2 bits (217), Expect = 4e-17
Identities = 118/461 (25%), Positives = 169/461 (36%), Gaps = 66/461 (14%)
Query: 704 IEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRI 763
I+G Y +R A N G +N K P P+ V VT +L W PP +
Sbjct: 17194 IDGGQYILR--ASNVAGSKSFPVNVKVLDRPGPPEGPVQ--VTGVTSEKCSLTWSPPLQD 17249
Query: 764 GAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPA 823
G I Y+VE W +E V V L G +FR++ VN G EP
Sbjct: 17250 GGSDISHYVVEKRETSRLAWTVVASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPL 17308
Query: 824 TLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG--------------EQLNLVVPFQGKPR 869
A + P P+ L T I K E + +V + + R
Sbjct: 17309 ESAPVLMKNPFVLPGP---PKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV--EKRDR 17363
Query: 870 PQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDT-----AT 924
+ W K + R+ T +R ++ EYE V EN AT
Sbjct: 17364 SGIRWIK----CNKRRI--------TDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17411
Query: 925 IRIRVVE---KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEW 979
+ + + K GPP N + + + + W P DG SEI+GY V+ KAD++ +
Sbjct: 17412 VYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQI 17471
Query: 980 FNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEY 1039
R T +S L EY RV N GL ++ V P
Sbjct: 17472 VTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV---------------PGTV 17516
Query: 1040 KEHDFRMAPKFLTPLIDR---VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLI 1096
K D AP+ R VV AG SA ++ +G P P++ W + + E + K I
Sbjct: 17517 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQI 17574
Query: 1097 TNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+I DAG Y + N G A ++V
Sbjct: 17575 EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17615
Score = 87.4 bits (215), Expect = 7e-17
Identities = 103/433 (23%), Positives = 161/433 (37%), Gaps = 50/433 (11%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++N K P P+ ++ VT TL W+PP + G I Y+VE
Sbjct: 16121 AKNVAGERSVTVNVKVLDRPGPPEGPV--VISGVTAEKCTLAWKPPLQDGGSDIINYIVE 16178
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAG-----RSEPATLAQPV 829
W + V+ V L G FR++ VN G SEP P
Sbjct: 16179 RRETSRLVWTVVDAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPF 16237
Query: 830 TIREIAEPPKIRLPRHLRQTYI----RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR 885
+ + + P++ + G L + + + + WT R
Sbjct: 16238 VVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT---------R 16288
Query: 886 VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPPI 937
H R +R ++ +YE V EN + + K GPP
Sbjct: 16289 CHKRLIG---ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN 16345
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSD 995
N V ++ ++ + W P DG EI GY V+K D EW T+ V
Sbjct: 16346 NPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEK 16405
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L+ +EY FR+ N G+ + V I + E + D + L +I
Sbjct: 16406 LLEKHEYNFRICAINKAGVGEHADVPGPI-------IVEEKLEAPDIDLDLE---LRKII 16455
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRPSPFD 1114
+ + AG S L ++G P P+V W K EIR+ +T ++ ++ N+ R +D
Sbjct: 16456 N--IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNR---YD 16510
Query: 1115 AGTYTCRAVNELG 1127
+G YT N G
Sbjct: 16511 SGKYTLTLENSSG 16523
Score = 87.4 bits (215), Expect = 7e-17
Identities = 98/404 (24%), Positives = 147/404 (36%), Gaps = 63/404 (15%)
Query: 713 VFAVNAIGVSQPSMNT----KPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGI 768
V A N+ G + +++ KP P+ P ++V+ + W PP G I
Sbjct: 17887 VTATNSAGTATENLSVIVLEKPGPPVGPVR------FDEVSADFVVISWEPPAYTGGCQI 17940
Query: 769 DGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQP 828
Y+VE + W + V R + L TG FR+ N G+S P
Sbjct: 17941 SNYIVEKRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV 17999
Query: 829 VTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV---------------VPFQGKPRPQVV 873
+ EP P ++ + + LV + K + ++
Sbjct: 18000 IVQYPFKEPGPPGTP------FVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18053
Query: 874 WTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSG-EYELSVQIENM----KDTATIRIR 928
W K ++ ++ + F T D G EYE V EN+ K +
Sbjct: 18054 WVK------LNKTPIQDTKFKTTGL-------DEGLEYEFKVSAENIVGIGKPSKVSECF 18100
Query: 929 VV-EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN- 986
V + PP + N ++W+ P DG S+I GY V+K D W N
Sbjct: 18101 VARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18160
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
T TVS L+ Y FRV N G P S IT + E + +
Sbjct: 18161 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGA-------ITARD-EIDAPNASL 18212
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRE 1090
PK+ + VV AG + L +RG P P VVW K+ E+ E
Sbjct: 18213 DPKYKDVI---VVHAGETFVLEADIRGKPIPDVVWSKDGKELEE 18253
Score = 86.7 bits (213), Expect = 1e-16
Identities = 91/398 (22%), Positives = 151/398 (37%), Gaps = 28/398 (7%)
Query: 633 LQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV 692
L +D P P + IT L W P Y GG +T Y+VE++ + RW+K NF
Sbjct: 14857 LDPIDPPGKPVPLNIT---RHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSN 14913
Query: 693 FTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTT 752
E + + + E YE RV A NA G P + E + V+ T
Sbjct: 14914 ILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDT 14973
Query: 753 TTLKWRPPNRIGA--GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFR 810
LK R+ A G +E+ +G E A E ++ F+ + + R
Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLE-IKIADFSTNLVNKDS--TRR 15030
Query: 811 VVGVNIAGRSEPATLAQPV-TIREIAEPPKIRLPRHLRQTYIRKV-----------GEQL 858
G + P A+ + ++ + P P + + K G ++
Sbjct: 15031 DSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15090
Query: 859 NLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIEN 918
+ + Q + ++ WT + + +++ V + R A + G E
Sbjct: 15091 DHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG------EP 15143
Query: 919 MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTME 978
++ + + PP N V + + +V W P DG SEI+ Y V++ DK
Sbjct: 15144 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 15203
Query: 979 WFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
W ++ VS L G+EY FR+ EN G+S
Sbjct: 15204 WIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 15241
Score = 86.7 bits (213), Expect = 1e-16
Identities = 227/1140 (19%), Positives = 382/1140 (33%), Gaps = 202/1140 (17%)
Query: 83 KPT--IKWF-KGKWLELGSK------SGA-RFSFKESHNSASNVYTVELHIGKVVLGDRG 132
KPT +KW+ G L+ SK SG + H S Y K D
Sbjct: 25903 KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASD-- 25960
Query: 133 YYRLEVKAKDTCDSCGFNIDVEAPRQ------DASGQSLESFKRTSEKKSDTAGELDFSG 186
Y L+V D D E PR ++ SFK+TSE ++ ++ S
Sbjct: 25961 YATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQ 26020
Query: 187 LLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLK 246
+ + RE + + + + + E +KS KI T +L + +
Sbjct: 26021 MTETRESLSSYEHSASAEMKSAALEEKSLE-----EKSTTRKIK----TTLAARILTKPR 26071
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFEN 306
V +SA F+ D +P T+ W + GQ + S+++
Sbjct: 26072 SMTVYEGESARFSCDTD-----------------GEPVPTVTWLRKGQVLSTSARHQVTT 26114
Query: 307 VGKKRILTINKCTLADDAAYEVAV-----KDEKCFTELFVKEPPVLIVTPLEDQQVFVGD 361
K I+ +D+ Y V V K E FT K + ++ V
Sbjct: 26115 TKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK-------ARVTEKAVTSPP 26167
Query: 362 RVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
RV+ + ++ K+ R K H S + +V
Sbjct: 26168 RVKSPEP---------------RVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKV 26212
Query: 422 ITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPS 481
+ I + + E ++IA LT + EV+ WYK+G +++ +
Sbjct: 26213 QHLPVSAPPK-ITQFLKAEASKEIAKLTCVVESSVLRAKEVT-------WYKDGKKLKEN 26264
Query: 482 KRITISH-VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLE----------IKV 530
+ ++L I+++ D+G+Y G + L F+ K+
Sbjct: 26265 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 26324
Query: 531 EYVPKQEPPKIHLDCSGKTSENAI-------VVVAG---------NKLRLDVSITGEPPP 574
K + + KT A V+V G + + V TGEP P
Sbjct: 26325 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 26384
Query: 575 VATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQ 634
A W K + T G+ ++ + I D G YT V N G +S L
Sbjct: 26385 TAIWTKDGKAITQG-GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLT 26443
Query: 635 VVDVPDPPEAVRITS------VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKL 688
+ + D EA ++++ + A++ E K + ++ + SQ + L
Sbjct: 26444 IKAIKDT-EAQKVSTQKTSEITPQKKAVVQEEISQ----KALRSEEIKMSEAKSQEKLAL 26498
Query: 689 NFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNT------KPFMPIAPTSEPLH 742
E E K E + SQ S K F +E
Sbjct: 26499 KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQR 26558
Query: 743 LIVEDVTDTTTTLKW---------RPPNRIGAGGIDGYLV----EYCLEGSEEWVPANTE 789
L+++ T +KW R G G D L + EG + E
Sbjct: 26559 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26618
Query: 790 PVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
+ +C + + T ++ L PA ++QP R
Sbjct: 26619 GIVKCQYDL----TLSKEL----------SDAPAFISQP------------------RSQ 26646
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSG 908
I + G+ + G+P P++ W K P+ +S V + S +R A+ SDSG
Sbjct: 26647 NINE-GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSG 26705
Query: 909 EYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
+Y + + + +AT + V+ P +V G +L
Sbjct: 26706 KYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL----------QGSFSSQS 26755
Query: 969 VQKADKKTMEWFNVYERNRHTSCT--------VSDLIVGNEYYFRVYTENICGLSDSPGV 1020
VQ + K F+ + + +S T + E + + + + G+S+ +
Sbjct: 26756 VQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQL 26815
Query: 1021 SKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVV 1080
+T+++LK GI P PK D + G + CA G P P+V
Sbjct: 26816 ESSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 26864
Query: 1081 WM--KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
W K+ +E +F I N + TL I D G YT NE G A + +R
Sbjct: 26865 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 26924
Score = 84.7 bits (208), Expect = 4e-16
Identities = 109/433 (25%), Positives = 158/433 (36%), Gaps = 52/433 (12%)
Query: 717 NAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
N G ++N K P + PL + +T +L W P G ID Y+VE
Sbjct: 19369 NVAGTRSVAVNCKVLDKPGPPAGPLE--INGLTAEKCSLSWGRPQEDGGADIDYYIVEKR 19426
Query: 777 LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAE 836
W E ++ V L G +FRV GVN G EP + V I+ +
Sbjct: 19427 ETSHLAWTICEGE-LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKALDP 19482
Query: 837 PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD---- 892
P L T + K E + L RP+ + GG+ + + R +
Sbjct: 19483 FTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERREKNSLRW 19532
Query: 893 --------FDTVFFVRQAARSDSGEYELSVQIEN-----MKDTATIRIRVVEKA---GPP 936
+D V+ + EYE V EN + + IR + PP
Sbjct: 19533 VRVNKKPVYD--LRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPP 19590
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDL 996
+ + T + W P DG + I GY V+ +W + R T T+S L
Sbjct: 19591 SKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 19650
Query: 997 IVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLID 1056
G EY FRV + N G SD S +I K +E F + + LI
Sbjct: 19651 TTGAEYVFRVKSVNKVGASDPSDSSD--PQIAKE-------REEEPLFDIDSEMRKTLI- 19700
Query: 1057 RVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAG 1116
V AG S + RG P P V+W K ++R + + +L I + D+G
Sbjct: 19701 --VKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIENANRNDSG 19756
Query: 1117 TYTCRAVNELGEA 1129
YT N L A
Sbjct: 19757 KYTLTIQNVLSAA 19769
Score = 84.3 bits (207), Expect = 6e-16
Identities = 200/926 (21%), Positives = 340/926 (36%), Gaps = 134/926 (14%)
Query: 286 TLKWFK-NGQEIKPSSKYVFENV--GKKRILTINKCTLADDAAYEVAVKDEKCFTELFV- 341
T KW + N + IK V E V K+ +L + A + V + +E V
Sbjct: 7831 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVR-------AVNAIGVSEPSEISENVVA 7883
Query: 342 KEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQV---MWMKDGVELTREDSFKARYRFK 398
K+P LE + V + ++++ V V W KDG E+ D R K
Sbjct: 7884 KDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD----RLTMK 7939
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
D L V+ D G Y + A + K + + D +KAS+
Sbjct: 7940 NDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD--IKASDITKS 7997
Query: 459 KCEVSDEKVTGKWYKNGVEV--------RPSKRITISHVGRFHKL--VIDDVRPEDEGDY 508
C+++ E + G + +R I + +KL + D+ P G+Y
Sbjct: 7998 SCKLTWEPPE---FDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPN--GEY 8052
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYV---PKQEP-PKIHLDCSGKTSENAIVVVAGNKLRL 564
F A++ ++E+K + PKQ P P + ++ T+E
Sbjct: 8053 FFRVK--AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA------------ 8098
Query: 565 DVSITGEPPPV--ATWLKGDEVFTTTEGRTRI----EKRVDCSSFVIESAQREDEGRYTI 618
++IT +PP + + G + +G R E V ++ + + E ++ +
Sbjct: 8099 -MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRV 8157
Query: 619 KVTNPVG---EDVASIFLQVVDVPDPPEAVRITSV---------------GEDWAILVWE 660
+ N G A+ + VD D P+ + TS+ G + + W
Sbjct: 8158 RAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWI 8217
Query: 661 PP----MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGIL-------- 708
+ + K LV R+K Q + + +++K E L
Sbjct: 8218 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 8277
Query: 709 ----YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764
Y ++V N G+++ P P++ + ED+ T+ KW PP G
Sbjct: 8278 DHGLYMIKV--ENDHGIAKAPCTVSVLDTPGP---PINFVFEDIRKTSVLCKWEPPLDDG 8332
Query: 765 AGGIDGYLVEYC--LEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEP 822
I Y +E + EW+ T + C ++V L G LFRV N G P
Sbjct: 8333 GSEIINYTLEKKDKTKPDSEWIVV-TSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8391
Query: 823 ATLAQPVTIREIAEPP----KIRLPRHLRQTYIRKVGEQLNLVVPFQG-----KPRPQVV 873
+++P+ ++ PP K + + + K E + P G +
Sbjct: 8392 C-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTH 8450
Query: 874 WTK-GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W++ + L+ + +V + R A + +G + S D T +
Sbjct: 8451 WSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP----SDPKTAH-DPISP 8505
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSC 991
GPPI V + T +EW+ P +G EI+GYFV K T EW E+ +
Sbjct: 8506 PGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQY 8564
Query: 992 TVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
TV ++ G +Y RV N G PG ++ +P E + ++ K
Sbjct: 8565 TVKEIREGADYKLRVSAVNAAG-EGPPGETQPVT-------VAEPQEPPAVELDVSVKGG 8616
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
++AG + + V G P P VW K + E+ +D + +I N L I+
Sbjct: 8617 IQ-----IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDAL 8670
Query: 1112 PFDAGTYTCRAVNELGEALAECKLEV 1137
D G Y A N G A ++EV
Sbjct: 8671 RKDHGRYVITATNSCGSKFAAARVEV 8696
Score = 84.3 bits (207), Expect = 6e-16
Identities = 117/447 (26%), Positives = 169/447 (37%), Gaps = 58/447 (12%)
Query: 715 AVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVE 774
A N G ++ N K P PL V +VT L W PP G ID Y+V+
Sbjct: 15039 ATNPGGFAKHIFNVKVLDRPGPPEGPL--AVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 15096
Query: 775 YCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI 834
W +E V+ V L G +FRV+ VN G EP ++PV
Sbjct: 15097 KRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-SEPVLAVNP 15154
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFD 894
PP P++ T I K + +V G P + GG+ + V R
Sbjct: 15155 YGPPDP--PKNPEVTTITK-----DSMVVCWGHPD-----SDGGSEIINYIVERRDKAGQ 15202
Query: 895 ----------TVFFVRQAARSDSGEYELSVQIENMKDTATIR--------IRVVEKAGPP 936
T + + ++ EYE + EN + V K GPP
Sbjct: 15203 RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPP 15262
Query: 937 INVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVS 994
N V + ++ + W P DG SEI GY V+ A + EW V + TS T++
Sbjct: 15263 GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTIT 15322
Query: 995 DLIVGNEYYFRVYTENICGLSDS---PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL 1051
L EY R+Y N GL + PG K R+L I + D R K +
Sbjct: 15323 GLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIEL------DADLR---KVV 15373
Query: 1052 TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTLNIRRP 1110
T + A + L ++G P P+V W ++ E + T +Y ++ N+ R
Sbjct: 15374 T------IRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNR- 15426
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
FD+G Y N G A + V
Sbjct: 15427 --FDSGKYILTVENSSGSKSAFVNVRV 15451
Score = 84.3 bits (207), Expect = 6e-16
Identities = 106/412 (25%), Positives = 143/412 (34%), Gaps = 70/412 (16%)
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
++T TL W P G I Y++E W + E +T L G
Sbjct: 21566 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNE 21624
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIR---EIAEPPKIRLPRHLRQTYIRKV--------G 855
FRV VN G P + PV + + + P I P ++ I G
Sbjct: 21625 YQFRVSAVNKFGVGRPLD-SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGG 21683
Query: 856 EQLNLVVPFQGKPRPQVVWTK--GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
++ + + + + W K P+ +R V ++ EYE
Sbjct: 21684 SEIQQYI-LERREKKSTRWVKVISKRPISETRFKV-------------TGLTEGNEYEFH 21729
Query: 914 VQIENMKDTAT-------IRIRV-VEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
V EN I+ R V GPP V V + T +EW P DG EI+
Sbjct: 21730 VMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21789
Query: 966 GYFVQKADKKTMEWFNVY-ERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS------- 1017
GY ++ +W V E T TV+DL G EY FRV N G DS
Sbjct: 21790 GYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTI 21849
Query: 1018 PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKP 1077
V + TA L FK VV AG S L A +G P P
Sbjct: 21850 KAVDRLTAPELDIDANFKQ-------------------THVVRAGASIRLFIAYQGRPTP 21890
Query: 1078 KVVWMK--NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
VW K + + +R D I TL + + DAG YT N G
Sbjct: 21891 TAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNRNDAGKYTLTVENNSG 21938
Score = 84.0 bits (206), Expect = 8e-16
Identities = 108/447 (24%), Positives = 166/447 (37%), Gaps = 71/447 (15%)
Query: 720 GVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEG 779
G Q ++ +P P+ P S ++VT + W+PP G I Y++E G
Sbjct: 10405 GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG 10458
Query: 780 SEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK 839
+ W+P T + V L G +FR+ N+ G S+P + + +
Sbjct: 10459 KDVWMPV-TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP------LVSDSMKAKDR 10511
Query: 840 IRLPRHLRQTYIRKVGEQLNLVV---PFQG-KPRPQVV------WTKGGAPLDTSRVHVR 889
R+P Q + +V + LV P G KP + +K A + +H
Sbjct: 10512 FRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPY 10571
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIEN---MKDTATIRIRV-----VEKAGPPINVMV 941
T R + +YE V EN + D + V + K PP+N
Sbjct: 10572 TK-------FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEA 10624
Query: 942 KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT--SCT-----VS 994
+ + + WQ P+ DG S+I+GY V+ EW R HT SC V+
Sbjct: 10625 IDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW----RRANHTPESCPETKYKVT 10680
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL--- 1051
L G Y FRV N G SD V + P K+ R+ P L
Sbjct: 10681 GLRDGQTYKFRVLAVNAAGESDPAHVPE-------------PVLVKD---RLEPPELILD 10724
Query: 1052 -TPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110
++ + G + L+ ++G P PKV W K + + +T L IR
Sbjct: 10725 ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNA 10782
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D G Y+ N G K+ V
Sbjct: 10783 AHEDGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 84.0 bits (206), Expect = 8e-16
Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 24/234 (10%)
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+++ R A ++ G + V +E + ++ E PP V + +V T+A + W+
Sbjct: 17687 IYYFRVMAENEFG---VGVPVETVD-----AVKAAEPPSPPGKVTLTDVSQTSASLMWEK 17738
Query: 956 PKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLS 1015
P+ DG S ++GY V+ K T +W V E ++ + V+ L G EY FRV N G S
Sbjct: 17739 PEHDGGSRVLGYVVEMQPKGTEKWSIVAE-SKVCNAVVTGLSSGQEYQFRVKAYNEKGKS 17797
Query: 1016 DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHP 1075
D R+L + K D + P P + AG + V G P
Sbjct: 17798 DP--------RVLGVPVIAK-------DLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRP 17842
Query: 1076 KPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
+P + W+K+ +++ + + L+I+ + D G YT A N G A
Sbjct: 17843 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA 17896
Score = 82.8 bits (203), Expect = 2e-15
Identities = 100/415 (24%), Positives = 149/415 (35%), Gaps = 52/415 (12%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ D+ +L W P G I Y+VE C +WV A V + V L G
Sbjct: 12504 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTKTSCRVGKLIPG 12562
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV---------- 854
+FRV N G SEP T + V P + P++ R T + K
Sbjct: 12563 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSE---PKNARVTKVNKDCIFVAWDRPD 12619
Query: 855 --GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
G + + K R ++W K L VR++++ V + EY
Sbjct: 12620 SDGGSPIIGYLIERKERNSLLWVKANDTL------VRSTEYPCAGLV------EGLEYSF 12667
Query: 913 SVQIENM-------KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIM 965
+ N K T + R+ PP V +V + + W PK DG S+I+
Sbjct: 12668 RIYALNKAGSSPPSKPTEYVTARM--PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKII 12725
Query: 966 GYFVQKADKKTMEWFNVYERNRHT---SCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
GYFV+ +W T + L +Y FR +S P
Sbjct: 12726 GYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP-PSEPS 12784
Query: 1023 NTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWM 1082
+ IL + D +A K L V AG + L+ V G P P V W
Sbjct: 12785 DPVTILAENVP------PRIDLSVAMKSLL-----TVKAGTNVCLDATVFGKPMPTVSWK 12833
Query: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
K+ ++ + + + TL + + D+G YT A N G A KL+V
Sbjct: 12834 KDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 12888
Score = 82.8 bits (203), Expect = 2e-15
Identities = 92/405 (22%), Positives = 156/405 (38%), Gaps = 35/405 (8%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+++V+ + T+ W PP G I Y+VE S W + + V R + L TG
Sbjct: 18999 IDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS-QAVARTSIKIVRLTTG 19057
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT-------YIRKVGEQ 857
+ FRV N G+S + + V + P P+ + T + V +
Sbjct: 19058 SEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDG 19117
Query: 858 LNLVVPF--QGKPRPQVVWTKGGAPLDT-SRVHVRTSDFDTVFFVRQAARSDSGEYELSV 914
+ V+ + + K R ++W+K L +++ V D ++ R A + +G + S
Sbjct: 19118 GSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSK 19177
Query: 915 QIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
E + + PP V + + ++W P DG ++I GY V++ +
Sbjct: 19178 SCEP--------VPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERREL 19229
Query: 975 KTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGIT 1033
W Y + T V++L Y FRV+ N P S++T I+
Sbjct: 19230 PDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEP--SESTGPIIVKDDV 19287
Query: 1034 FKPFEYKEHDFRMAPKFLTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDP 1092
P + FR D +VV AG +N + G P P + W K+ +EI E
Sbjct: 19288 EPPRVMMDVKFR----------DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 19337
Query: 1093 KFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG--EALAECKL 1135
+ I + L ++ D G Y N G CK+
Sbjct: 19338 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382
Score = 81.6 bits (200), Expect = 4e-15
Identities = 98/461 (21%), Positives = 173/461 (37%), Gaps = 79/461 (17%)
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
AK+ V+ + + QV + + E+++ D+ W+K+G EI + + V
Sbjct: 3092 AKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYV 3151
Query: 308 GKKRI--LTINKCTLADDAAYEVAVKDEKCFTELFVKEP-PVLIVTPLEDQQVFVGDRVE 364
++RI + I++ +D Y + L+V P P ++ L+ V G
Sbjct: 3152 VERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPAR 3211
Query: 365 MAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQED-------- 415
+S ++ W K+ E FK + F DG+ + L+ + ED
Sbjct: 3212 FCAVISGRPQPKISWYKE--EQLLSTGFKCK--FLHDGQEYTLLLIEAFPEDAAVYTCEA 3267
Query: 416 RGRYQVITNGGQCEAEL---IVEEKQLEV-----LQDIADLTVKASEQAVFKCEVSDEKV 467
+ Y V T E+ + ++++ V + + D + A F+C VS +
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3327
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYA--------LSL 519
WY +++PS+ ++ ++L I + PEDEG YTFV LSL
Sbjct: 3328 KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Query: 520 SAKLNFLEIKVEYVPKQE---------------------------------------PPK 540
A + L ++E + E P K
Sbjct: 3388 EAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTK 3447
Query: 541 IHLDCSG------KTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
+ G K NA + + G+ L V++ G P P W + V T +
Sbjct: 3448 FDSEKEGTGPIFIKEVSNADISM-GDVATLSVTVIGIPKPKIQWF-FNGVLLTPSADYKF 3505
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
D S +I + EDEG YT +N G+ + S +L++
Sbjct: 3506 VFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3546
Score = 77.8 bits (190), Expect = 5e-14
Identities = 95/402 (23%), Positives = 156/402 (38%), Gaps = 45/402 (11%)
Query: 745 VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTG 804
+ +V+ TL W PP G I Y++E W + E ++ C L G
Sbjct: 13984 ISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSCRHVATKLIQG 14042
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP----KIRLPRHLRQT----YIRKVGE 856
+FRV VN G+ EP ++PV + + PP K + + T + R V +
Sbjct: 14043 NEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14101
Query: 857 QLNLVVPF--QGKPRPQVVWTKG-GAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELS 913
+ + + + + + + W + P+ R V + + R +A + +G S
Sbjct: 14102 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14161
Query: 914 VQIEN--MKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 971
++ MKD A GPP N V + +A + W P DG EI GY V+
Sbjct: 14162 EASDSVLMKDAAY-------PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14214
Query: 972 ADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILK 1029
W R T V DL +Y FR+ N G+ + P V + + +
Sbjct: 14215 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGE-PAVIPDVEIVER 14273
Query: 1030 TGITFKPFEYKEHDFRMAPKF-LTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKM 1086
MAP F L + R +V AG S + ++G P P+V W K+ +
Sbjct: 14274 ---------------EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14318
Query: 1087 EIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
++ + I N + L I + +D G + N G+
Sbjct: 14319 NLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGK 14358
Score = 77.4 bits (189), Expect = 7e-14
Identities = 77/267 (28%), Positives = 117/267 (43%), Gaps = 21/267 (7%)
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV----KDEKCFTELFVKEP 344
W K+G I+ S K+ F GK R L I L+D Y + K++ +L V+E
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713
Query: 345 PVLIVTPLEDQQVFV-GDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
PV V LE++ V G + ++ E+++E V+W KDG + + R G
Sbjct: 4714 PVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDGKIVVEK---PGRIVPGVIGLM 4769
Query: 404 HILIFSDVVQEDRGRYQV-ITNGGQCEAELIVEEKQLEVLQD-----IADLTVKASEQAV 457
L +D D G Y V + N E V K +EV++D I D VK A+
Sbjct: 4770 RALTINDADDTDAGTYTVTVENANNLECSSCV--KVVEVIRDWLVKPIRDQHVKPKGTAI 4827
Query: 458 FKCEVSDEKVTGKWYKNGVEV--RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGY 515
F C+++ + KW+K E+ P+ + I G L I + PED +Y +G
Sbjct: 4828 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG- 4886
Query: 516 ALSLSAKLNFLEIKVEYVPKQEPPKIH 542
AKL E +VE + E I+
Sbjct: 4887 -KRYPAKLTLGEREVELLKPIEDVTIY 4912
Score = 77.4 bits (189), Expect = 7e-14
Identities = 139/622 (22%), Positives = 222/622 (35%), Gaps = 82/622 (13%)
Query: 563 RLDVSITGEPPPVATWLKGDEVFTTTEGRTRI-----EKRVDCSSFVIESAQRED----- 612
RLDV T + V WLK D +G +RI E R S F +E+ +
Sbjct: 22054 RLDVVDTSKSSAVLAWLKPDH-----DGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22108
Query: 613 -------EGRYTIKVTNPVG-----EDVASIFLQVVDVPDPPEAVRITS------VGEDW 654
E + +K N G E +S+ ++ + + IT+ G +
Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22168
Query: 655 AILVWEPPMYDGGKP---VTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEM 711
I V P+ G+P VT L E + K + R + T T + + + Y +
Sbjct: 22169 TIDV---PI--SGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 22223
Query: 712 RVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGY 771
+ N GV S+ P + P+ V V+ + L W P G I Y
Sbjct: 22224 TL--ENTAGVKTFSVTVVVIGRPGPVTGPIE--VSSVSAESCVLSWGEPKDGGGTEITNY 22279
Query: 772 LVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI 831
+VE G+ W N+ V+R V +L FRV N G S+P A P+
Sbjct: 22280 IVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESA-PIIA 22337
Query: 832 REIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF------------QGKPRPQVVWTKGGA 879
PP P ++ + P+ + K R ++W K
Sbjct: 22338 EHPFVPPSA--PTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVK--- 22392
Query: 880 PLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINV 939
++V ++ V + Y L+ + A+ I P
Sbjct: 22393 ---ENKVPCLECNYKVTGLV-EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP 22448
Query: 940 MVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTM---EWFNV-YERNRHTSCTVSD 995
V +V + + W AP DG S+++GY +++ + W Y TV+
Sbjct: 22449 EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTA 22508
Query: 996 LIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLI 1055
L G+ Y FRV +N G+ +SK + TG EY + + L+
Sbjct: 22509 LSEGDTYEFRVLAKNAAGV-----ISKGSE---STGPVTCRDEYAPPKAELDARLHGDLV 22560
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ AG L+ AV G P+PK++W K E+ K + T I+ D+
Sbjct: 22561 --TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDS 22618
Query: 1116 GTYTCRAVNELGEALAECKLEV 1137
G YT N G ++V
Sbjct: 22619 GKYTLTVKNASGTKAVSVMVKV 22640
Score = 77.0 bits (188), Expect = 9e-14
Identities = 53/204 (25%), Positives = 88/204 (43%), Gaps = 16/204 (7%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
++ E+ PP + + +V + + W+ P+ DG S I+GY V+ K + +W
Sbjct: 15546 VKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATC-ATV 15604
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ T T++ LI G EY FRV +N G+SD R L + K D +
Sbjct: 15605 KVTEATITGLIQGEEYSFRVSAQNEKGISDP--------RQLSVPVIAK-------DLVI 15649
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P F V+AG ++ G P P V W K+ + +++ + + + L
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15709
Query: 1107 IRRPSPFDAGTYTCRAVNELGEAL 1130
I+ D G Y + N GEA+
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAI 15733
Score = 74.7 bits (182), Expect = 5e-13
Identities = 97/436 (22%), Positives = 155/436 (35%), Gaps = 49/436 (11%)
Query: 713 VFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYL 772
+ A N+ G ++ K P P + + + L W PP G I Y+
Sbjct: 12871 ITAENSSGSKSATIKLKVLDKPGP---PASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927
Query: 773 VEYCLEGSEEWVPAN-TEPVERCGFTVKNLPTGARILFRVVGVNIAGR-----SEPATLA 826
V+ W + T P+ C +V+ L G FR+ N G +EPA
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSC--SVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAK 12985
Query: 827 QPVTIREIAEPPKIR--LPRHLRQTYIRKVGEQLNLVVPF--QGKPRPQVVWTKGGAPLD 882
P +PP I H+ ++ + + + + + + V WTK ++
Sbjct: 12986 NPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK----VN 13041
Query: 883 TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMK--------DTATIRIRVVEKAG 934
+ RT ++ + EYE V N A G
Sbjct: 13042 RKPIIERT--------LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPG 13093
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ--KADKKTMEWFNVYERNRHTSCT 992
PP V + ++ + W P DG S I+GY V+ +AD N+ + + T
Sbjct: 13094 PPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFE 13153
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
V+ L+ +Y FRVY N G SD V + I P + D R
Sbjct: 13154 VTGLMEDTQYQFRVYAVNKIGYSDPSDVPD---KHYPKDILIPPEGELDADLRKT----- 13205
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
++ AG + L V+G P PK+ W K + +R+ I + L +
Sbjct: 13206 ----LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 13261
Query: 1113 FDAGTYTCRAVNELGE 1128
+DAG Y N G+
Sbjct: 13262 YDAGKYILTLENSCGK 13277
Score = 73.6 bits (179), Expect = 1e-12
Identities = 105/414 (25%), Positives = 152/414 (36%), Gaps = 56/414 (13%)
Query: 742 HLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNL 801
+L + DV+ T+ W PP G I Y++E C W + V G TV L
Sbjct: 11805 NLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATVLTPGTTVTRL 11863
Query: 802 PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLV 861
G +FRV N G P T ++PV + + P P + KV ++ V
Sbjct: 11864 IEGNEYIFRVRAENKIGTGPP-TESKPVIAKTKYDKPGRPDPPE-----VTKVSKEEMTV 11917
Query: 862 V----PFQG-----------KPRPQVVWT---KGGAPLDTSRVHVRTSDFDTVFFVRQAA 903
V + G K + W K P +V D + F V+
Sbjct: 11918 VWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAEN 11977
Query: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
GE L + KD +E GPP N V + + + W P DG +
Sbjct: 11978 EIGIGEPSLPSRPVVAKDP-------IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12030
Query: 964 IMGYFVQK----ADKKTMEWF---NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
I+GY V+ AD E + N + TV+ L EY FRV +N G+
Sbjct: 12031 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12090
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
+ + KP E E + L+ +V AG L VRG P
Sbjct: 12091 PAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGRPA 12138
Query: 1077 PKVVWMKNKME--IREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
PKV W K ++ +R+ L+ ++ N R D+G Y+ VN GE
Sbjct: 12139 PKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRD---DSGKYSLTLVNPAGE 12189
Score = 73.6 bits (179), Expect = 1e-12
Identities = 101/421 (23%), Positives = 155/421 (36%), Gaps = 60/421 (14%)
Query: 743 LIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLP 802
L V VT L W PP + G I Y++E W +TE V+ + V L
Sbjct: 18312 LKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE-VQALNYKVTKLL 18370
Query: 803 TGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP--------KIRLPRHLRQTYIRKV 854
G +FRV+ VN G EP + PVT +PP + T+ R V
Sbjct: 18371 PGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPV 18429
Query: 855 GEQLNLVVPF--QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYEL 912
+ + + + + + V WTK T +R ++ YE
Sbjct: 18430 DDGGTEIEGYILEKRDKEGVRWTKCNKKTLTD------------LRLRVTGLTEGHSYEF 18477
Query: 913 SVQIENMKDTA-----TIRIRVVEKA---GPPINVMVKEVWGTNALVEWQAPKDDGNSEI 964
V EN ++ R + GPP N V + ++ + W P DG + +
Sbjct: 18478 RVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPV 18537
Query: 965 MGYFVQKADKKTMEWFNVYERN--RHTSCTVSDLIVGNEYYFRVYTENICGLSDS---PG 1019
GY V+ + EW + TV+ L EY FR+ N G+ + PG
Sbjct: 18538 KGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPG 18597
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC--AVRGHPKP 1077
RI I + D R +VVV SA L ++G P+P
Sbjct: 18598 SVVAQERIEPPEIEL------DADLR-----------KVVVLRASATLRLFVTIKGRPEP 18640
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTL-NIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136
+V W K + + + + +T+ +L + N+ R FD+G Y N G A +
Sbjct: 18641 EVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR---FDSGRYNLTLENNSGSKTAFVNVR 18697
Query: 1137 V 1137
V
Sbjct: 18698 V 18698
Score = 70.1 bits (170), Expect = 1e-11
Identities = 61/232 (26%), Positives = 96/232 (41%), Gaps = 25/232 (10%)
Query: 905 SDSGEYELSVQIENM-----KDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
S+ EY V EN T ++ E PP ++ + ++ + + W PK D
Sbjct: 14435 SEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHD 14494
Query: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
G S+I GY ++ K + +W ++ + C V +L G EY F+V N G S +P
Sbjct: 14495 GGSKITGYVIEAQRKGSDQWTHI-TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS-APR 14552
Query: 1020 VSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTPLIDRVVVA--GYSAALNCAVRGHPK 1076
S+ P KE M P+ L + ++V+A G + + V G PK
Sbjct: 14553 ESR-------------PVIVKEQT--MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPK 14597
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
P V W K +++ + LNI D+G Y A N +GE
Sbjct: 14598 PTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 14649
Score = 69.7 bits (169), Expect = 1e-11
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 31/279 (11%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
KW K E+R + I ++ F LV+D+V D G YT + S K F+ ++
Sbjct: 16478 KWGKVDGEIRDAAIIDVT--SSFTSLVLDNVNRYDSGKYTLTLEN---SSGTKSAFVTVR 16532
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
V P P ++L + T ++ VSIT EPP + K
Sbjct: 16533 VLDTPS---PPVNLKVTEITKDS-------------VSITWEPPLLDGGSKIKNYIVEKR 16576
Query: 590 GRTR-----IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF---LQVVDVPDP 641
TR + +S+ I+ Q + + N G + + ++V +VP P
Sbjct: 16577 EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQP 16636
Query: 642 PEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYEST 701
P + + V + L W P +DGG + Y+VE + K S++W + + T
Sbjct: 16637 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVI--T 16694
Query: 702 KMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEP 740
+ +G Y RV AVN G S P P + EP
Sbjct: 16695 NLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP 16733
Score = 69.3 bits (168), Expect = 2e-11
Identities = 81/305 (26%), Positives = 128/305 (41%), Gaps = 40/305 (13%)
Query: 429 EAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISH 488
E EL + +++ VL+ A L + + + + EV EK G + R I
Sbjct: 18609 EIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL---------TDRAQIEV 18659
Query: 489 VGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK 548
F LVID+V D G Y + + +K F+ ++V LD
Sbjct: 18660 TSSFTMLVIDNVTRFDSGRYNLTLEN---NSGSKTAFVNVRV------------LD---- 18700
Query: 549 TSENAIVVVAGNKLRLD-VSITGEPPPVATWLK-----GDEVFTTTEGRTRIEKRVDCSS 602
S +A V + +++ D V+++ EPP + K ++ TT + I ++
Sbjct: 18701 -SPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTT 18759
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV---PDPPEAVRITSVGEDWAILVW 659
F IE+ Q + + +N G + + + V V P PP V + V + A + W
Sbjct: 18760 FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 18819
Query: 660 EPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAI 719
E P DGG +TGY+VE + KGS++W E T + G Y RV AVN
Sbjct: 18820 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISG--LTAGEEYVFRVAAVNEK 18877
Query: 720 GVSQP 724
G S P
Sbjct: 18878 GRSDP 18882
Score = 68.2 bits (165), Expect = 4e-11
Identities = 79/289 (27%), Positives = 122/289 (42%), Gaps = 32/289 (11%)
Query: 340 FVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKK 399
FVKE +I+T E FVG VS A WMKDG + ++RF
Sbjct: 4620 FVKEIKDIILTESE----FVGSSAIFECLVSPSTAITTWMKDGSNIRE----SPKHRFIA 4671
Query: 400 DGKRHILIFSDVVQEDRGRYQVITNGGQCE----AELIVEEKQLEVLQDI-ADLTVKASE 454
DGK L DV D G Y + G E A+L+VEE + ++ + ++TV +
Sbjct: 4672 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ 4731
Query: 455 QAVFKCEVSDEKVTGKWYKNG-VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VP 512
CE++ E+ W K+G + V RI +G L I+D D G YT V
Sbjct: 4732 PLYLSCELNKERDV-VWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVE 4790
Query: 513 DGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEP 572
+ L S+ + +E+ +++ K P + D K AI D++ +
Sbjct: 4791 NANNLECSSCVKVVEVIRDWLVK--PIR---DQHVKPKGTAI-------FACDIA---KD 4835
Query: 573 PPVATWLKG-DEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
P W KG DE+ +T I + + I++A ED Y +++
Sbjct: 4836 TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEI 4884
Score = 68.2 bits (165), Expect = 4e-11
Identities = 106/473 (22%), Positives = 165/473 (34%), Gaps = 51/473 (10%)
Query: 679 KKGSQ---RWMKLNFEVF-TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPI 734
KKG Q + ++NFE T T + + + A N +G + +
Sbjct: 14603 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP 14662
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 794
P + P+ ++V+ T W PP G I Y+VE S WV T + R
Sbjct: 14663 GPPTGPIKF--DEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 14719
Query: 795 GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKV 854
+ L TG FRV N G T A V P P+ T + K
Sbjct: 14720 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQ---VTAVTKD 14776
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF------------VRQA 902
++ P + GG+P+ HV + + + + + +
Sbjct: 14777 SMTISWHEPL----------SDGGSPI--LGYHVERKERNGILWQTVSKALVPGNIFKSS 14824
Query: 903 ARSDSGEYELSVQIENMKDTA-----TIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPK 957
+D YE V ENM + + + ++ PP + + ++W P+
Sbjct: 14825 GLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPE 14884
Query: 958 DDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
G +I Y V+K D W N TVS L Y FRV +N G
Sbjct: 14885 YTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAIS 14944
Query: 1017 SPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK 1076
P + IT + + + ++ KF +I + AG + L V G P
Sbjct: 14945 PPSEPSDA-------ITCRD-DVEAPKIKVDVKFKDTVI---LKAGEAFRLEADVSGRPP 14993
Query: 1077 PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
P + W K+ E+ K I L + + D+G YT A N G A
Sbjct: 14994 PTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 15046
Score = 67.4 bits (163), Expect = 7e-11
Identities = 87/398 (21%), Positives = 151/398 (37%), Gaps = 60/398 (15%)
Query: 271 GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV-- 328
G + +S DL + W+ ++IKPS + L I + D+ Y
Sbjct: 3313 GQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3372
Query: 329 --AVKDEKCFTELFVKEPPVLIVTPLEDQ-QVFVGDRVEMAVEVSEEGA-----QVMWMK 380
AV L ++ P ++ +E + ++ + + + EEG Q+ +
Sbjct: 3373 SNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKIN 3432
Query: 381 DGVELTREDS-FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQL 439
+ +EL E + ++ +K+G I I +V D I+ G
Sbjct: 3433 ETLELLSESPVYPTKFDSEKEGTGPIFI-KEVSNAD------ISMG-------------- 3471
Query: 440 EVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
D+A L+V + K +W+ NGV + PS G H L+I
Sbjct: 3472 ----DVATLSVTV---------IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3518
Query: 500 VRPEDEGDYT-FVPDGYALSLSA---KLN-----FLEIKVEYVPKQEPPKIHLDCSGKTS 550
+ EDEG+YT + Y ++ + K+N + + E + K+ C
Sbjct: 3519 TKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFL 3578
Query: 551 ENA--IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
+ I G + ++ GEP P TW K ++ T+ T I +F++
Sbjct: 3579 KELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDP 3638
Query: 609 QREDEGRYTIKVTNPVGEDVAS----IFLQVVDVPDPP 642
QRED G Y K N +GE + + L+ D+ D P
Sbjct: 3639 QREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3676
Score = 67.0 bits (162), Expect = 1e-10
Identities = 58/205 (28%), Positives = 84/205 (40%), Gaps = 19/205 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHT-SCTVS 994
P ++ VKEV + W PK DG SEI+ Y ++ T ++ V N + TV
Sbjct: 10223 PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVK 10282
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFL-TP 1053
L G+ Y +RV NI G K KP K+ +AP L
Sbjct: 10283 GLKEGDTYEYRVSAVNIVGQG-------------KPSFCTKPITCKDE---LAPPTLHLD 10326
Query: 1054 LIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
D++ + G + AL G PKPKV W K++ ++ ED + I L L +
Sbjct: 10327 FRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKR 10386
Query: 1113 FDAGTYTCRAVNELGEALAECKLEV 1137
D+G Y N G C++ V
Sbjct: 10387 SDSGKYCVVVENSTGSRKGFCQVNV 10411
Score = 65.9 bits (159), Expect = 2e-10
Identities = 242/1196 (20%), Positives = 419/1196 (35%), Gaps = 189/1196 (15%)
Query: 41 EDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKS 100
E+Q+ E F+ KP + G V +V G KP + W K G
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP---KPHVYWKKS-----GVPL 1076
Query: 101 GARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDA 160
+ +K S+N + +L I D G Y + V+ K S ++ EA +
Sbjct: 1077 TTGYRYKVSYNKQTG--ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL 1134
Query: 161 SGQSLESFKRTS-------EKKSDTAGELDFSGLLKKREVVEEE-KKKKKKDDDDLGIPP 212
E +T K +TA +S K+ E + +KK KD +
Sbjct: 1135 MKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYV 1194
Query: 213 EIWEL-LKGAKKSEYEKIAFQYGITDLRGMLKR--LKKAKVEVKKSAAFTKKLDPA---Y 266
E E + ++ ++I ++ T L +L+ +K V++ +S A D Y
Sbjct: 1195 EDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNY 1254
Query: 267 QVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRI-LTINKCTLADDA 324
++ G + ++S L + W+K+G+ IK +Y + + R L I D+
Sbjct: 1255 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314
Query: 325 AYEVAVKDEK----CFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMK 380
Y + K C +L+V EP + P + R+ S + +
Sbjct: 1315 IYTAFASNIKGNAICSGKLYV-EPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSP 1373
Query: 381 DGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE 440
+ R + G+R ++E +E QLE
Sbjct: 1374 ARMSPARMSPARMSPARMSPGRR--------LEE-------------------TDESQLE 1406
Query: 441 VLQDIADLTVKASEQAVFKCEVS-----DEKVTGK------WYKNGVEVRP--SKRITIS 487
L V + FKC D KV G+ W+ +G ++ + ++ I
Sbjct: 1407 RLYK----PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIK 1462
Query: 488 HVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSG 547
G L+I P D G++T V A S + + VE V Q P
Sbjct: 1463 EDGT-QSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---LTVEAVEHQVKPMFVEKLKN 1518
Query: 548 KTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE-GRTRIEKRVDCSSFVIE 606
+ + G++L + V TG P P WLK ++ + + RIE ++ I+
Sbjct: 1519 ------VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1572
Query: 607 SAQREDEGRYTIKVTNPVGEDVASIFLQV-VDVPDP-PEAVRITSVGEDWAILVWEPPMY 664
S +D YT N G D + V V+ +P PE I G A + P +
Sbjct: 1573 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPEL- 1631
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
+P+ + G ++W EG LY+
Sbjct: 1632 ---EPL------HLRYGQEQWE------------------EGDLYDKEKQQKPFFKKKLT 1664
Query: 725 SMNTKPFMP------IAPTSEPLHLI--VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
S+ K F P + P +P ++ + D + R N G +D Y V Y
Sbjct: 1665 SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD-YGVAYS 1723
Query: 777 LE------------GSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
+ G++ E+ LP G + L R+ + E A
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH-EGAL 1782
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS 884
+E +P + P +R GE G P+P+V W G + S
Sbjct: 1783 TGVTTDQKEKQKPDIVLYPEPVRVL----EGETARFRCRVTGYPQPKVNWYLNGQLIRKS 1838
Query: 885 R--------VH----VRTSDFDTVFFVRQAARSDSG--EYELSVQIENMKDTATIRIRV- 929
+ +H V +DT V+ A + G E+++ ++I+ +D ++ R
Sbjct: 1839 KRFRVRYDGIHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1897
Query: 930 -----------------VEKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V+K P++ V ++ + + P++ + E+ F
Sbjct: 1898 EPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE--SEELRSKF 1955
Query: 969 VQKADKKTMEWFNVYE-RNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
++ ++ E E ++R + +L+ + +T+ + + K A
Sbjct: 1956 KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKEL-----TEEEKKALAEE 2010
Query: 1028 LKTGI-TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
K I TFKP + + APK + + V G A V G P P+ W KN +
Sbjct: 2011 GKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGV 2070
Query: 1087 EI-REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+I R D + V L IR + D+ + +A+N GE + L V+ Q
Sbjct: 2071 KIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 17/203 (8%)
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
I E+ PP + V + ++A++ W P DG S I GY ++ K + W
Sbjct: 22043 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 22101
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRM 1046
+ + TV L+ EY FRV +N G S+ F KE
Sbjct: 22102 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREA-------------FSSVIIKEPQIEP 22148
Query: 1047 APKFLTPLIDRVVV--AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104
LT + ++++ AG ++ + G P PKV W +M ++E + IT + T
Sbjct: 22149 TAD-LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTT 22207
Query: 1105 LNIRRPSPFDAGTYTCRAVNELG 1127
L ++ D+G Y N G
Sbjct: 22208 LTVKDSMRGDSGRYFLTLENTAG 22230
Score = 65.5 bits (158), Expect = 3e-10
Identities = 33/94 (35%), Positives = 46/94 (48%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P ++ L + V+ G S L C + G+P P V W + +I F IT G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
R D+G +TC AVNE G C L V+V +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 990
Score = 65.5 bits (158), Expect = 3e-10
Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 18/219 (8%)
Query: 922 TATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFN 981
T + I +++ G P N+ + + T ++W+ P DG S + Y V++ K + +W
Sbjct: 11593 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 11652
Query: 982 VYERNRHTSCTVSDLIVGNEYY-FRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYK 1040
V++ + + + D V N+ Y FRV T+N G SD K ++K + + K
Sbjct: 11653 VHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWV---KTEEVVVKEDLQKPVLDLK 11709
Query: 1041 EHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK--MEIREDPKFLITN 1098
L+ ++ V AG + L VRG P P+V W K+K ++ P+ I
Sbjct: 11710 ----------LSGVL--TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDT 11757
Query: 1099 YQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + D G Y A N G +A + V
Sbjct: 11758 RADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 65.1 bits (157), Expect = 4e-10
Identities = 75/317 (23%), Positives = 124/317 (39%), Gaps = 50/317 (15%)
Query: 269 DRGNKIKLMVEISDPDLTLK--WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G +K + +I + D + + W+ ++++ S KY IL + T DD Y
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142
Query: 327 EVAV----KDEKCFTELFVK---------------------------EPPVLIVTPLEDQ 355
V ++ + ELFVK E P PL ++
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25202
Query: 356 QVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQE 414
+VG+ V V ++ V W K G ++ D+ K +Y F+ D + L + V +
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFESDKGLYQLTINSVTTD 25261
Query: 415 DRGRYQVITNG----GQCEAELIV------EEKQLEVL--QDIADLTVKASEQAVFKCEV 462
D Y V+ C+A+L V + L + + +A+ + + F+ V
Sbjct: 25262 DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRV 25321
Query: 463 SD-EKVTGKWYKNGVEVRPSKRITISHVG-RFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
S T KW K+G + I I H G ++ L I D PED G Y A S S
Sbjct: 25322 SGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTS 25381
Query: 521 AKLNFLEIKVEYVPKQE 537
+ + ++ Y KQE
Sbjct: 25382 CQAHLQVERLRY-KKQE 25397
Score = 60.5 bits (145), Expect = 9e-09
Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 19/196 (9%)
Query: 936 PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYE-RNRHTSCTVS 994
P + V +V + + W+ P DG S + GY ++ T W V + TV+
Sbjct: 23141 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23200
Query: 995 DLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF-LTP 1053
L G +Y FR+ +N G+S+ R T +T + D R+ P L+
Sbjct: 23201 SLNEGEQYLFRIRAQNEKGVSEP--------RETVTAVTVQ-------DLRVLPTIDLST 23245
Query: 1054 LIDRV--VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPS 1111
+ + V AG L + G P P W ++RE + + + V L IR +
Sbjct: 23246 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETT 23305
Query: 1112 PFDAGTYTCRAVNELG 1127
D G YT N G
Sbjct: 23306 IRDTGEYTLELKNVTG 23321
Score = 59.7 bits (143), Expect = 2e-08
Identities = 69/295 (23%), Positives = 117/295 (39%), Gaps = 27/295 (9%)
Query: 348 IVTPLEDQQVFVGDRVEMAVEV-SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
I + +V G + V S+ A+V W +GVEL ++S K Y G +
Sbjct: 25879 ITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESSKIHYT-NTSGVLTLE 25935
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
I D +D G Y+ + + EA D A L V + + + DE+
Sbjct: 25936 IL-DCHTDDSGTYRAVCTNYKGEAS------------DYATLDVTGGDYTTYASQRRDEE 25982
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDG---YALSLSAKL 523
V + E+ ++ +S + ++ E + T + Y S SA++
Sbjct: 25983 VPRSVFP---ELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEM 26039
Query: 524 NFLEIKVEYVP-KQEPPKIHLDCSGK--TSENAIVVVAGNKLRLDVSITGEPPPVATWLK 580
++ + + K KI + + T ++ V G R GEP P TWL+
Sbjct: 26040 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
+V +T+ R ++ S+F I S Q DEG Y++ V N G+ A L +
Sbjct: 26100 KGQVLSTS-ARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26153
Score = 59.3 bits (142), Expect = 2e-08
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 31/222 (13%)
Query: 439 LEVLQDIADLTVKASE----QAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHK 494
L+ +++I D+ + SE A+F+C VS W K+G +R S + G+ K
Sbjct: 4618 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677
Query: 495 LVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAI 554
L I DV+ D G+YT V L K + ++ VE +P + KT E +
Sbjct: 4678 LHIIDVQLSDAGEYTCV---LRLGNKEKTSTAKLVVEELPVR---------FVKTLEEEV 4725
Query: 555 VVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 614
VV G L L + E V W K ++ GR + I A D G
Sbjct: 4726 TVVKGQPLYLSCELNKERDVV--WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAG 4783
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
YT+ V N + +S V++ V DW +
Sbjct: 4784 TYTVTVENANNLECSS-------------CVKVVEVIRDWLV 4812
Score = 59.3 bits (142), Expect = 2e-08
Identities = 118/608 (19%), Positives = 216/608 (35%), Gaps = 90/608 (14%)
Query: 6 PAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPT------GVFLKKPD 59
P K+P+ P+ EA ++P+ + P+ SPT +PT + + P
Sbjct: 26166 PPRVKSPE----PRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPP 26221
Query: 60 SVS----VETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGARFSFKESHNSAS 114
++ E K+ + V + + W+K GK L K F F H SA
Sbjct: 26222 KITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL----KENGHFQF---HYSAD 26274
Query: 115 NVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEA-----PRQDASGQSLESFK 169
Y EL I + D+G Y E+ + +A + ++ +S +
Sbjct: 26275 GTY--ELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQ 26332
Query: 170 RTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLG----------IPPEIWELLK 219
+T+E E + + V+ + D + P IW
Sbjct: 26333 KTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIW---- 26388
Query: 220 GAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKL-DPAYQVDRGNKIKLMV 278
K + +Y +++ +G L+ K + S +T + + A V K+ +
Sbjct: 26389 -TKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26446
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
I D + + EI P K V + ++ L + +++ + E E+
Sbjct: 26447 -IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKV 26505
Query: 339 LFVKEPPVLIVTPLE---------------------------DQQVFVGDRVEMAVEVSE 371
L +E T LE Q+ + + + ++ +
Sbjct: 26506 LISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANI 26565
Query: 372 EGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI--TNGG-- 426
GA V W+ +GVELT + YR+ G L D G I T G
Sbjct: 26566 AGATDVKWVLNGVELTNSE----EYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIV 26621
Query: 427 QCEAELIVEEKQLEV---LQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSK 482
+C+ +L + ++ + + + + +F CE+S E +W+KN + + S
Sbjct: 26622 KCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISS 26681
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
++IS + L I + D G YT + SA + + + + P +E +
Sbjct: 26682 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSRE---VV 26738
Query: 543 LDCSGKTS 550
L SG TS
Sbjct: 26739 LRTSGDTS 26746
Score = 56.6 bits (135), Expect = 1e-07
Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 605 IESAQREDEGRYTIKVTNPVGEDVAS------IFLQVVDVPDPPEAVRITSVGEDWAILV 658
+++ + E ++ +K N +G S + ++ P PP R+ + L
Sbjct: 11960 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 12019
Query: 659 WEPPMYDGGKPVTGYLVERKKK-----GSQRWMKLNFEV-FTETTYESTKMIEGILYEMR 712
W P+YDGG P+ GY+VE + K + W + N + T + E YE R
Sbjct: 12020 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 12079
Query: 713 VFAVNAIGVSQPS 725
V A N +G+ +P+
Sbjct: 12080 VCAQNQVGIGRPA 12092
Score = 56.2 bits (134), Expect = 2e-07
Identities = 50/208 (24%), Positives = 85/208 (40%), Gaps = 25/208 (12%)
Query: 935 PPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ-KADKKTMEWFNVYERNRHTSCTV 993
PP + V E+ +A + W P DG ++I GY + +++ + + Y + S V
Sbjct: 12304 PPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVV 12363
Query: 994 SDLIVGNEYYFRVYTENICGLS---DSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF 1050
+ L G +Y FRV N G+S ++ GV Y+ + + PK
Sbjct: 12364 TGLKEGKKYKFRVAARNAVGVSLPREAEGV------------------YEAKEQLLPPKI 12405
Query: 1051 LTPLIDRVVV-AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
L P +++ + AG + V G P P W K + E+ + L I+
Sbjct: 12406 LMP--EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 12463
Query: 1110 PSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ D+G Y+ A N G + K+ V
Sbjct: 12464 VTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 55.1 bits (131), Expect = 4e-07
Identities = 53/239 (22%), Positives = 92/239 (38%), Gaps = 24/239 (10%)
Query: 907 SGEYELSVQIENMKDTATIRIR-----VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGN 961
S E E S ++ AT++I+ ++++ GP I+ + + +
Sbjct: 4210 SEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA 4269
Query: 962 SEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVS 1021
E+ YF K ++ + ++N +T V D + ++ E +C + G +
Sbjct: 4270 KEVNWYFENKLVPSDEKFKCLQDQNTYT--LVIDKVNTEDHQ----GEYVCEALNDSGKT 4323
Query: 1022 KNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVW 1081
+A++ R AP + V G+ A C ++ P + W
Sbjct: 4324 ATSAKLTVVK-------------RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 4370
Query: 1082 MKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
K EI E K I + + + +L I R D G YTC+A NE G L V VP
Sbjct: 4371 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 55.1 bits (131), Expect = 4e-07
Identities = 59/225 (26%), Positives = 87/225 (38%), Gaps = 30/225 (13%)
Query: 927 IRVVEKAGPPIN---VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
I V+ GPP + + E + ++W+ P+ +G S I GY ++K ++ V
Sbjct: 8789 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8848
Query: 984 ERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEH 1042
+R TS V +L Y FRV N G S+ P + P
Sbjct: 8849 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE-PSL---------------PLNVVIQ 8892
Query: 1043 DFRMAPKFLTPLIDR----VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL--- 1095
D + P L R V AG + V G P PK+ W KN+ I + L
Sbjct: 8893 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 8952
Query: 1096 ---ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++ + L+I + D GTYT A N LG +EV
Sbjct: 8953 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997
Score = 55.1 bits (131), Expect = 4e-07
Identities = 72/327 (22%), Positives = 125/327 (38%), Gaps = 24/327 (7%)
Query: 518 SLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVAT 577
+L + + EI PK + P I + N V N L +TG P P+
Sbjct: 24406 NLGGESEWSEISEPITPKSDVP-IQAPHFKEELRNLNVRYQSNAT-LVCKVTGHPKPIVK 24463
Query: 578 WLKGDEVFTTTEGRTRIEK-RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV- 635
W + + + RI++ + +I S +D Y ++ TN G + L+V
Sbjct: 24464 WYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Query: 636 ----VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE 691
+ +P E + + + P GKP ++ +K +++
Sbjct: 24524 VPAKIHLPKTLEGMGAVHALRGEVVSIKIP---FSGKPDP--VITWQKGQDLIDNNGHYQ 24578
Query: 692 VFTETTYESTKMIEGILYEMRVFAV----NAIGVSQPSMNTKPFMPIAPTSEPLHLI-VE 746
V ++ S G+ + F V N G+ Q ++ + +A +P + V
Sbjct: 24579 VIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVE----LDVADVPDPPRGVKVS 24634
Query: 747 DVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGAR 806
DV+ + L W P G I Y+VE C +E W+ R +TV NL
Sbjct: 24635 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR--YTVINLFGKTS 24692
Query: 807 ILFRVVGVNIAGRSEPATLAQPVTIRE 833
FRV+ N G S+P+ ++P +E
Sbjct: 24693 YQFRVIAENKFGLSKPSEPSEPTITKE 24719
Score = 51.2 bits (121), Expect = 5e-06
Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P +TPL D V G A C V G KV W +I+ F +T ++ L I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P D GTYT A N +G+ + L + P+
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3391
Score = 51.2 bits (121), Expect = 5e-06
Identities = 68/310 (21%), Positives = 115/310 (37%), Gaps = 56/310 (18%)
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQ--VITN 424
+E ++ QV W +L + ++ Y +DG IL D+ + D G Y+ V+ +
Sbjct: 25094 IENYDQSTQVTWYFGVRQLENSEKYEITY---EDGVA-ILYVKDITKLDDGTYRCKVVND 25149
Query: 425 GGQCE--AELIVE---------------------------EKQLEVLQDIADLTVKASEQ 455
G+ AEL V+ E+ E + + T E
Sbjct: 25150 YGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN 25209
Query: 456 AVFKCEVS---DEKVTGKWYKNGVEVRPS---KRITISHVGRFHKLVIDDVRPEDEGDYT 509
F ++ + VT WYK+G +++P K+ T ++L I+ V +D+ +YT
Sbjct: 25210 VRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYT 25267
Query: 510 FVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVA----GNKLRLD 565
V S K V PP D + + ++ A G + +
Sbjct: 25268 VVARNKYGEDSCKAKLT------VTLHPPPT---DSTLRPMFKRLLANAECQEGQSVCFE 25318
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 625
+ ++G PPP W K + + I + +D + I ED G Y + TN G
Sbjct: 25319 IRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25378
Query: 626 EDVASIFLQV 635
LQV
Sbjct: 25379 STSCQAHLQV 25388
Score = 49.3 bits (116), Expect = 2e-05
Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 17/204 (8%)
Query: 443 QDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKR--ITISHVGRFHKLVIDD 499
Q + + V A F+ +S V W+++G + S + IS KL I
Sbjct: 10 QPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPA 69
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V + G Y+ + ++ L +K E P ++ ++ V G
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELL-VKAETAPPNFVQRLQ----------SMTVRQG 118
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+++RL V +TG P PV + + G E+ ++ + +I + D S +I A ED G Y++
Sbjct: 119 SQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 619 KVTNPVGEDVASIFLQVVDVPDPP 642
TN VG ++ L V + P
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVP 200
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Query: 351 PLEDQQVFVGDRVEMAVEVSEEGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFS 409
PL+ V G +S +V W +DG ++ + F DG+ + I +
Sbjct: 11 PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRAKLTIPA 69
Query: 410 DVVQEDRGRYQV-ITNG-GQCE--AELIVEEKQL--EVLQDIADLTVKASEQAVFKCEVS 463
V + + GRY + TNG GQ AEL+V+ + +Q + +TV+ Q + V+
Sbjct: 70 -VTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 464 DEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
K+Y++G E++ S IS G + L+I + PED G Y+
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/94 (30%), Positives = 40/94 (42%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P+ L L V +G A + G P+PK+ W K + + K + TL +
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P DA YTC A N+ G A L V VP+
Sbjct: 3253 IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR---EDPKFLITNYQGVLT 1104
P+F PL ++ G + + HP+P V W K+ +I+ D K+ + +G+
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L I + D YT A N+ GE + KL V
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 48.5 bits (114), Expect = 4e-05
Identities = 76/332 (22%), Positives = 117/332 (35%), Gaps = 51/332 (15%)
Query: 243 KRLKKAKVEVKKSAAFTKKLDP-------AYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQ 294
++ + K EV FT P +++V G + ++ + S P +KW+ NG
Sbjct: 25856 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 25915
Query: 295 EIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLED 354
E++ SSK + N L I C D Y + K + L VT
Sbjct: 25916 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYA----TLDVTG--- 25968
Query: 355 QQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGK-------RHILI 407
GD A + +E ELTR +++ A FKK + R +
Sbjct: 25969 -----GDYTTYASQRRDEEVPRSVFP---ELTRTEAY-AVSSFKKTSEMEASSSVREVKS 26019
Query: 408 FSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE---------------VLQDIADLTVKA 452
+E Y+ + A L EEK LE +L +TV
Sbjct: 26020 QMTETRESLSSYEHSASAEMKSAAL--EEKSLEEKSTTRKIKTTLAARILTKPRSMTVYE 26077
Query: 453 SEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511
E A F C+ E V T W + G + S R ++ I V+ DEG+Y+ V
Sbjct: 26078 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVV 26137
Query: 512 PDGYALSLSAKLNFLEIKVEYVPK--QEPPKI 541
+ A+ K K PP++
Sbjct: 26138 VENSEGKQEAEFTLTIQKARVTEKAVTSPPRV 26169
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/91 (32%), Positives = 40/91 (43%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
AP+ + V G + V+ P +V W N +E++E K TN GVLTL
Sbjct: 25876 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 25935
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
I D+GTY N GEA L+V
Sbjct: 25936 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 46.2 bits (108), Expect = 2e-04
Identities = 47/176 (26%), Positives = 78/176 (44%), Gaps = 12/176 (6%)
Query: 341 VKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKD 400
+KE +I TPL D GD V + ++ +V W + + ++ FK +D
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLVPSDEKFKCL----QD 4292
Query: 401 GKRHILIFSDVVQED-RGRY--QVITNGGQC--EAELIVEEKQLEVLQ-DIADLTVKASE 454
+ L+ V ED +G Y + + + G+ A+L V ++ V++ I L V
Sbjct: 4293 QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGH 4352
Query: 455 QAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
A F CE+ S V +W+K G E+ S + +I L I + D G+YT
Sbjct: 4353 LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4408
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 1032 ITFKPFEYKEHDFRMAP--KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR 1089
+T K F+ + F P +F PL D+ V G +A L C V KV W KN EI
Sbjct: 5770 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEIL 5828
Query: 1090 EDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
+ K+ I V L I +P D TYTC A
Sbjct: 5829 KSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861
Score = 44.7 bits (104), Expect = 5e-04
Identities = 48/210 (22%), Positives = 76/210 (36%), Gaps = 28/210 (13%)
Query: 457 VFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGY 515
V K E D+ WY ++ S++ I++ L + D+ D+G Y V + Y
Sbjct: 25091 VCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDY 25150
Query: 516 ALSLSAKLNFL----EIKVEYVPK---------------QEPPKIHLDCSGKTSENAIVV 556
S F+ E+ Y + + PP+ L KT+
Sbjct: 25151 GEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA------ 25204
Query: 557 VAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSF--VIESAQREDEG 614
G +R V+IT P P TW K + + + D + I S +D+
Sbjct: 25205 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 25264
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEA 644
YT+ N GED L V P P ++
Sbjct: 25265 EYTVVARNKYGEDSCKAKLTVTLHPPPTDS 25294
Score = 44.3 bits (103), Expect = 7e-04
Identities = 28/91 (30%), Positives = 42/91 (46%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P F+ L V G L V G P P V + ++ EI+ F I+ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
P D+GTY+ A N +G A + +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 1/91 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF-LITNYQGVLTLN 1106
P FL L G A V G P P V W K ++ + +I N G T
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+ P D+G Y C+A N LGE+ +L V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED--PKFLITNYQGVLT 1104
AP F PL VV+ G +A + G P P+V W ++ I P I+ G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L I + ++G Y+ +A N G+A + +L V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/170 (22%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
++VV+ G+ + I+G P P +W + G + T+T +I + I + +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
+ GRY++K TN G+ ++ L V PP V+ ++ V + VT
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-----SMTVRQGSQVRLQVRVT 128
Query: 672 GY---LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
G +V+ + G++ L+F++ E S + E + ++VNA
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNA 178
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/285 (21%), Positives = 104/285 (36%), Gaps = 41/285 (14%)
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDR-----GRYQVITNGGQCEAELIVEEKQLEVLQ 443
D++K+ + + + I V+E+R GR +T + A + + ++
Sbjct: 842 DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVS 901
Query: 444 DIADLTVKASEQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRP 502
+ ++TV E +C +S T WY+ ++ S I+ +L+I +
Sbjct: 902 GLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFA 961
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKV-EYVPKQ----------------EPPKIHLDC 545
ED G +T A ++S +L ++V E K+ E + +
Sbjct: 962 EDSGRFTCSAVNEAGTVSTSC-YLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1020
Query: 546 SGKTSENA--------------IV--VVAGNKLRLDVSITGEPPPVATWLKGDEVFTT-T 588
+ T E A +V +V G + + G P P W K TT
Sbjct: 1021 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGY 1080
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
+ K+ VI +D G YTI V N GE AS L
Sbjct: 1081 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 40.4 bits (93), Expect = 0.010
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
+ V+ G + L+ I+G P P TW + D ++ ++ + + + + + +I A ED
Sbjct: 906 VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLMIREAFAED 963
Query: 613 EGRYTIKVTNPVGEDVASIFLQV 635
GR+T N G S +L V
Sbjct: 964 SGRFTCSAVNEAGTVSTSCYLAV 986
Score = 39.3 bits (90), Expect = 0.022
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 4/104 (3%)
Query: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI--REDPK 1093
P ++ P F+ + + + G A L+ V G PKPK+ W N + + D K
Sbjct: 3445 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3504
Query: 1094 FLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
F+ L + + D G YTC A N+ G+ + L++
Sbjct: 3505 FVFDGDDHSLIILFTKLE--DEGEYTCMASNDYGKTICSAYLKI 3546
Score = 38.9 bits (89), Expect = 0.028
Identities = 19/61 (31%), Positives = 31/61 (50%)
Query: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+V W ++ K+ IT GV L ++ + D GTY C+ VN+ GE + +L V
Sbjct: 25102 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161
Query: 1138 R 1138
+
Sbjct: 25162 K 25162
Score = 38.1 bits (87), Expect = 0.048
Identities = 48/197 (24%), Positives = 83/197 (42%), Gaps = 29/197 (14%)
Query: 287 LKWFKNGQEIK----PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEK----CFTE 338
+ WF++GQ I P + F + K LTI T A+ Y + + E
Sbjct: 37 VSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTAE 94
Query: 339 LFVKEP--PVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM-WMKDGVELTREDSFKARY 395
L VK P V L+ V G +V + V V+ V+ + +DG E+ F+
Sbjct: 95 LLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQ--- 151
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQV-ITNG---GQCEAELIVEEKQLEVLQDIADLTVK 451
++G + L+ ++ ED G Y V TN AEL+V+ ++ ++ K
Sbjct: 152 -ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--------EVPAK 202
Query: 452 ASEQAVFKCEVSDEKVT 468
++ V ++S+ + T
Sbjct: 203 KTKTIVSTAQISESRQT 219
Score = 37.7 bits (86), Expect = 0.063
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 14/105 (13%)
Query: 830 TIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR 889
T+R + PP+ LP + + Y VGE + V P P V W K G ++
Sbjct: 25185 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIK 25234
Query: 890 TSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAG 934
D D + SD G Y+L++ D A + K G
Sbjct: 25235 PGDNDK----KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 25275
Score = 37.4 bits (85), Expect = 0.082
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 21/97 (21%)
Query: 237 DLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQE 295
DLRG+ ++L AK G+ IK+ + + P T+ W K Q
Sbjct: 14569 DLRGIYQKLVIAKA--------------------GDNIKVEIPVLGRPKPTVTWKKGDQI 14608
Query: 296 IKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKD 332
+K + + FE IL IN+C +D Y + ++
Sbjct: 14609 LKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14645
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 22/93 (23%)
Query: 1006 VYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSA 1065
VYT + G K +AR+ TGI K F++PL D+ V G +A
Sbjct: 5056 VYTAEVEG-------KKTSARLFVTGIRLK--------------FMSPLEDQTVKEGETA 5094
Query: 1066 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITN 1098
C + H K VVW KN ++ LI++
Sbjct: 5095 TFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISS 5126
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 1/82 (1%)
Query: 252 VKKSAAFTKKLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKK 310
V S KL V G ++ I P T KW +G EIK Y E
Sbjct: 11009 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11068
Query: 311 RILTINKCTLADDAAYEVAVKD 332
+LTI C D Y++ V +
Sbjct: 11069 SVLTIKNCLRRDTGEYQITVSN 11090
Score = 36.2 bits (82), Expect = 0.18
Identities = 57/267 (21%), Positives = 99/267 (37%), Gaps = 40/267 (14%)
Query: 874 WTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W + G L T+ + + + D GEY + ++ K +A +++ V+
Sbjct: 2606 WLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVKI 2663
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT 992
N+ V E VE P G I V ++++K + + + S
Sbjct: 2664 KKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEK----YAISVKGTIYSLR 2719
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
+ + + +E VY + L S + T +I+K PK +T
Sbjct: 2720 IKNCAIVDE---SVYGFRLGRLGASARLHVETVKIIKK-----------------PKDVT 2759
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
L + V S + H V W +EI+ K + + + V L ++ SP
Sbjct: 2760 ALENATVAFEVSVS-------HDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2812
Query: 1113 FDAGTYTCRAVNELGEALAECKLEVRV 1139
DAG YT V +L ECK ++ V
Sbjct: 2813 SDAGEYTA-VVGQL-----ECKAKLFV 2833
Score = 36.2 bits (82), Expect = 0.18
Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D + P F L + G S V G P P + W K+ + P I ++G+
Sbjct: 25293 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25351
Query: 1103 --LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L+IR P D G Y A N G + L+V
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 34.7 bits (78), Expect = 0.53
Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 243 KRLKKAKVEVKKSAA--FTKKLDPAYQVDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPS 299
K AK+ V K AA +K++P +V G+ K EI S P++ +WFK G+EI S
Sbjct: 4322 KTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTCEIQSAPNVRFQWFKAGREIYES 4380
Query: 300 SKYVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKEP 344
K + L I + + D Y +E C L V P
Sbjct: 4381 DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDTVFFVRQAAR 904
Q+ + G G P P+V W + G + TS V + SD + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
++SG Y L + + T+T + V + PP
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 268 VDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G ++L++ I+ P WF G +++ S + E K LTI + T+ D Y
Sbjct: 23253 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEY 23312
Query: 327 EVAVKD 332
+ +K+
Sbjct: 23313 TLELKN 23318
Score = 32.3 bits (72), Expect = 2.6
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 873 VWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
VW K G + S RVH+ + + + D+G Y ++ + + + + V+
Sbjct: 2341 VWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400
Query: 932 KAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
P +V V E GT A++E + D S
Sbjct: 2401 VITPLKDVNVIE--GTKAVLECKVSVPDVTS 2429
Score = 32.0 bits (71), Expect = 3.4
Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 268 VDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K+ + V + P T+ W K+G+E+K S + +N L + K AD Y
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 7960
Query: 327 EVAVKDE 333
+ ++++
Sbjct: 7961 TITLENK 7967
Score = 31.6 bits (70), Expect = 4.5
Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 6/122 (4%)
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK-----FLTPLIDRVVVAGY 1063
+N+C L ++++A I+ I E H F + F L D V
Sbjct: 2085 DNVCELVIRDVTAEDSASIMVKAINIAG-ETSSHAFLLVQAKQLITFTQELQDVVAKEKD 2143
Query: 1064 SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAV 1123
+ A P KV W K+ ME+ E K+ + + + V L+I DA Y+C V
Sbjct: 2144 TMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 1124 NE 1125
+
Sbjct: 2204 ED 2205
Score = 31.6 bits (70), Expect = 4.5
Identities = 60/257 (23%), Positives = 100/257 (38%), Gaps = 50/257 (19%)
Query: 45 PTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFK-GKWLELGSKSGAR 103
PT +F + + + G+ +V+G +P PT+KW K G+ L LG
Sbjct: 25291 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG--IPP-PTLKWEKDGQPLSLGPNI--- 25344
Query: 104 FSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPR-QDASG 162
E + + Y LHI + D GYYR+ SC ++ VE R +
Sbjct: 25345 ----EIIHEGLDYYA--LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEF 25398
Query: 163 QSLESFKRTSEKKSDTAGELDFSGLLKKREVV--EEEKKKKKKDDDDLGIPPEIWELLKG 220
+S E +R +K+ D L + +L E V + K+ ++ L P + +KG
Sbjct: 25399 KSKEEHERHVQKQIDKT--LRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKG 25456
Query: 221 ------AKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKI 274
+K E K+ Y + + R + K+ +E +I
Sbjct: 25457 EFRLEIEEKKEERKLRMPYDVPEPR----KYKQTTIE------------------EDQRI 25494
Query: 275 KLMVEISDPDLTLKWFK 291
K V +SD +KW+K
Sbjct: 25495 KQFVPMSD----MKWYK 25507
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 261 KLDPAYQVDRGNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCT 319
KL V G KI+L ++ P+ + W K +K + ENV KK +TI
Sbjct: 7198 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSK 7257
Query: 320 LADDAAY 326
+D Y
Sbjct: 7258 RSDTGTY 7264
Score = 30.8 bits (68), Expect = 7.7
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+FL PL D V A C + KV W K+ EI++ K+ I + V L I
Sbjct: 5878 EFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVIN 5936
Query: 1109 RPSPFDAGTYTC 1120
+ D Y+C
Sbjct: 5937 KCLLDDEAEYSC 5948
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 266 bits (680), Expect = 8e-71
Identities = 223/815 (27%), Positives = 339/815 (41%), Gaps = 53/815 (6%)
Query: 352 LEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDV 411
L D +V G+ ++ ++ + W KDGV+LT +D FK+DG H L + V
Sbjct: 79 LADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVI----FKQDGLVHSLFITHV 134
Query: 412 VQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIAD-----LTVKASEQAVFKCEVSDE- 465
GRY + Q EA L V++ + D+ + L VKA + + K
Sbjct: 135 QGTQAGRYTFVAGDQQSEATLTVQDSPT-IAPDVTEKLREPLVVKAGKPVIVKIPFQSHL 193
Query: 466 KVTGKWYKNGVEVRPS--KRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKL 523
+ W K+G EV S + + + +L + +D G Y+ S+ A
Sbjct: 194 PIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQA-- 251
Query: 524 NFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPV-------A 576
E+ ++ + K +PP+ ++ + A V + R + T E V +
Sbjct: 252 ---ELTLQVIDKPDPPQGPMEV--QDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRS 306
Query: 577 TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV----TNPVGEDVAS-- 630
TWLK E S A E +YT +V + GE + S
Sbjct: 307 TWLKVGEA--------------PADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEE 352
Query: 631 IFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNF 690
I + +P P A I S L W P G + GYL+ER+KKGS W +N
Sbjct: 353 ILVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVND 412
Query: 691 EVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---PIAPTSEPLHLIVED 747
+ E + + +G YE RV AV G +P + P+ P +L V D
Sbjct: 413 QPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTD 472
Query: 748 VTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARI 807
++T+ TL W P+ GY+VE C S +W+P + V +T K L G
Sbjct: 473 RSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGY 532
Query: 808 LFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGK 867
RV VN G+S+P+ L V + PK + + KVG+ + + V F+
Sbjct: 533 FVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAM 592
Query: 868 PRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTA-TIR 926
P P+V W K G PL V V T D T + A SDSG Y + ++ K+ A + R
Sbjct: 593 PMPEVTWLKDGLPLPKRSVTV-TKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFR 651
Query: 927 IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN 986
IRV P + ++E EW+ D+ + Y V W +R
Sbjct: 652 IRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRI 711
Query: 987 RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKN-TARILKTGITFKPFEYKEHDFR 1045
T+ ++ G+EY+FRV +N G S S+ + T K Y+E D
Sbjct: 712 HTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLS 771
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
P+FL L ++ G ++CAV+G P+P V W KN + +P T+ GV +L
Sbjct: 772 QKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSL 831
Query: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
I SP D+G Y A N LG+A++ L V P
Sbjct: 832 TIPSVSPKDSGEYKAVAENTLGQAVSTATLIVIEP 866
Score = 159 bits (403), Expect = 1e-38
Identities = 115/410 (28%), Positives = 183/410 (44%), Gaps = 18/410 (4%)
Query: 443 QDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRP 502
Q +AD+ V+ E A C ++ + G W+K+GV++ + G H L I V+
Sbjct: 77 QGLADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQG 136
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKL 562
G YTFV + + Q+ P I D + K E +VV AG +
Sbjct: 137 TQAGRYTFVAGDQQSEATLTV------------QDSPTIAPDVTEKLRE-PLVVKAGKPV 183
Query: 563 RLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVT 621
+ + P A W K G EV +++ +++ + + SA R+D G+Y++ +
Sbjct: 184 IVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLR 243
Query: 622 NPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
+ G A + LQV+D PDPP+ + + L W PP +GG+ V Y+VER++
Sbjct: 244 SEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQA 303
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-PIAPTSE 739
G W+K+ TT+ + G Y RV AV + G + + + + P A
Sbjct: 304 GRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKA 363
Query: 740 PLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVK 799
P + + TL W P G+ I GYL+E +GS W N +PV +TV
Sbjct: 364 PSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVA 423
Query: 800 NLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQT 849
++ G + FRV V +G EP + V R+ PP L R+L+ T
Sbjct: 424 DVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPP--GLVRNLQVT 471
Score = 56.6 bits (135), Expect = 1e-07
Identities = 108/506 (21%), Positives = 178/506 (35%), Gaps = 75/506 (14%)
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLI 348
WFK+G ++ +F+ G L I Y D++ L V++ P +
Sbjct: 105 WFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPTIA 164
Query: 349 --VTPLEDQQVFVGDRVEMAVEV---SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
VT + + V + V++ S Q W KDG E+ +A+ R
Sbjct: 165 PDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTR 224
Query: 404 HILIFSDVVQEDRGRYQVI--TNGGQCEAELIVE--------EKQLEVLQDIADLTV--- 450
L ++D G+Y V + GG +AEL ++ + +EV QD V
Sbjct: 225 --LCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEV-QDCHRAGVCLR 281
Query: 451 ----KASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKRITISHV--GRFHKLVIDDVRP 502
+ + +C V + + G+ W K G S T +HV GR + + V
Sbjct: 282 WRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTS 341
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKL 562
E G+ LE + V + PK + +A +++ +
Sbjct: 342 EGAGE-----------------ALESEEILVAPEALPK---------APSAPAILSASSQ 375
Query: 563 RLDVSITGEPPPVATWL---------KGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDE 613
+ ++ T P + + KG +T + E+R + + ++ +
Sbjct: 376 GITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERR-----WTVADVRQGCQ 430
Query: 614 GRYTIKVTNPVGEDVASIFLQVVDVPD---PPEAVR---ITSVGEDWAILVWEPPMYDGG 667
+ + P G V D PP VR +T L W P G
Sbjct: 431 YEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEG 490
Query: 668 KPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMN 727
GY+VE S +W+ + TTY + + G Y +RV AVN G SQPS
Sbjct: 491 DEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSAL 550
Query: 728 TKPFMPIAPTSEPLHLIVEDVTDTTT 753
+ T P L+ D T
Sbjct: 551 DTLVQAMPVTVCPKFLVDSSTKDLLT 576
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 132 bits (333), Expect = 1e-30
Identities = 138/525 (26%), Positives = 216/525 (41%), Gaps = 96/525 (18%)
Query: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
VP PP V + + ++ +L WEPP G P+ Y +E+ GS W ++N + +
Sbjct: 510 VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSP 568
Query: 698 -YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPT---SEPLHLIVEDVTDTTT 753
Y ++EG Y RV + N G+S+PS T P T S P ++ T T+
Sbjct: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSV 628
Query: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813
++W P + GY V+ C+ G+ W P N +P+ F V L TG + +FRV
Sbjct: 629 VVQWDRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686
Query: 814 VNIAGRSEPATLAQPVTIREIAEPPKIRLPRH-LRQTYIRKVGEQLNLVVPFQGKPRPQV 872
VN G SE + + + ++ + +P H T + G + L G P+
Sbjct: 687 VNAVGMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTL-----GWKVPKF 736
Query: 873 VWTKGGAP-----LDTSRVH---------------VRTSDFDT---VFFVRQAARSDSGE 909
GG+P LD VH + T D T ++ + AA + +G
Sbjct: 737 ---SGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793
Query: 910 YELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFV 969
E S E+ K A + + GP ++ EV T+ ++ W+AP G+S + GYFV
Sbjct: 794 GEPSDPSEHFKCEAW----TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFV 849
Query: 970 QKADKKTMEWFNVYE---RNRHTSCTVSDLIVGNEYYFRVYTENICGL---SDS------ 1017
++ EW V + NR+ VSDL G Y FRV N G+ SD+
Sbjct: 850 DFREEDAGEWITVNQTTTANRYLK--VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLV 907
Query: 1018 ---PGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGH 1074
PG + +A + + G + F+ +E A +F
Sbjct: 908 EARPGTKEISAGVDEQGNIYLGFDCQE--MTDASQF------------------------ 941
Query: 1075 PKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1119
W K+ EI +D +F I L ++ P D GTY+
Sbjct: 942 -----TWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYS 981
Score = 120 bits (302), Expect = 6e-27
Identities = 115/498 (23%), Positives = 198/498 (39%), Gaps = 55/498 (11%)
Query: 574 PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
P A W + D+V T++ +S ++DEG YT+++ + G S FL
Sbjct: 312 PRAEWYR-DDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFL 370
Query: 634 QVVDV-------PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWM 686
V D P P ++ D+ I+ W+PP PV GY V+R + G+ W+
Sbjct: 371 FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430
Query: 687 KLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTS----EPLH 742
+ N Y T + EG Y RV AVN+ G+S+PS + + P + +H
Sbjct: 431 QCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVH 490
Query: 743 LIVE--------------------------DVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
L E +++ L W PP G + Y +E
Sbjct: 491 LEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKS 549
Query: 777 LEGSEEWVPANTEPVERC-GFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREI- 834
+ GS W N + R + V +L G +FRV+ N G SEP+ + P+ +++
Sbjct: 550 VVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVT 609
Query: 835 ---AEPPKIRLPRHLRQTYI----RKVGEQLNLVVPFQGKPRPQVVWTK-GGAPLDTSRV 886
+ P ++ R+ + + + R E+ L +W P+ +R
Sbjct: 610 VVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRF 669
Query: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWG 946
V + R A + G E S + + +K A + + P + + G
Sbjct: 670 VVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTV-----PSHPYGITLLNCDG 724
Query: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYER-NRHTSCTVSDLIVGNEYYFR 1005
+ + W+ PK G S I+GY++ K + W V ++ T TV L G+ Y F+
Sbjct: 725 HSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFK 784
Query: 1006 VYTENICGLSDSPGVSKN 1023
+ N+ G+ + S++
Sbjct: 785 IAAVNLAGIGEPSDPSEH 802
Score = 107 bits (267), Expect = 6e-23
Identities = 81/333 (24%), Positives = 140/333 (42%), Gaps = 24/333 (7%)
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV------PDPPEAVRITS 649
K + + FV+ ++ + +K N VG S V+ V P P + + +
Sbjct: 662 KPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLN 721
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
L W+ P + GG P+ GY +++++ + W ++N T + EG LY
Sbjct: 722 CDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLY 781
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIA---PTSEPLH-LIVEDVTDTTTTLKWRPPNRIGA 765
E ++ AVN G+ +PS ++ F A P P + L +V DT+ + W+ P G+
Sbjct: 782 EFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGS 841
Query: 766 GGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATL 825
+ GY V++ E + EW+ N V +L G +FRV VN G +P+
Sbjct: 842 SPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDT 901
Query: 826 AQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF---QGKPRPQVVWTKGGAPL- 881
++PV + +I V EQ N+ + F + Q W K +
Sbjct: 902 SEPVLVEARPGTKEIS----------AGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEIS 951
Query: 882 DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSV 914
D R + T + +++ + D G Y +SV
Sbjct: 952 DDERFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984
Score = 74.7 bits (182), Expect = 5e-13
Identities = 114/532 (21%), Positives = 190/532 (35%), Gaps = 83/532 (15%)
Query: 562 LRLDVSITGEPPPVATWLKGDEVF--TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619
++L ++ G P PV W K + G+ RIE + I A +D Y+
Sbjct: 171 VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAV 230
Query: 620 VTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKK 679
TN G+ + + V E R + + P + + + + V ++
Sbjct: 231 ATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRR 290
Query: 680 KG--------------------------------SQRWMKLNF-EVFTETTYESTKMIEG 706
+G +W K+ F E ++ +
Sbjct: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDE 350
Query: 707 ILYEMRVFAVNAIGVSQPS-----MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPN 761
LY +R+ V+ GVS S + P + AP P+ L D + W+PPN
Sbjct: 351 GLYTLRI--VSRGGVSDHSAFLFVRDADPLVTGAP-GAPMDLQCHDANRDYVIVTWKPPN 407
Query: 762 RIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSE 821
+ GY V+ C G+ WV N PV+ C + V L G +FRV VN AG S
Sbjct: 408 TTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISR 467
Query: 822 PATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP---------RPQV 872
P+ ++ V + + +++ + I + L G P R V
Sbjct: 468 PSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYV 527
Query: 873 V--W----TKGGAPL------------DTSRVHVRTSDFDTVFFVRQAARSDSGEYE-LS 913
V W +G PL RV+ +T+ + V S + LS
Sbjct: 528 VLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLS 587
Query: 914 VQIENMKDTATIR-------IRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966
+ + + I + VV A P V+ T+ +V+W PK + +++G
Sbjct: 588 ANRHGLSEPSEITSPIQAQDVTVVPSA--PGRVLASRNTKTSVVVQWDRPKHE--EDLLG 643
Query: 967 YFVQKADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS 1017
Y+V T W ++ + V L G +Y FRV N G+S++
Sbjct: 644 YYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSEN 695
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/155 (27%), Positives = 68/155 (43%), Gaps = 13/155 (8%)
Query: 884 SRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKE 943
SRV + D + R A GE E+++ ++++ A + GPP V E
Sbjct: 469 SRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQV-------PGPPTGVHASE 521
Query: 944 VWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSCTVSDLIVGNE 1001
+ ++ W+ P G +M YF++K+ + W V + R V DL+ G
Sbjct: 522 ISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKS 580
Query: 1002 YYFRVYTENICGLSDSPGVSKNTARILKTGITFKP 1036
Y FRV + N GLS+ S+ T+ I +T P
Sbjct: 581 YVFRVLSANRHGLSEP---SEITSPIQAQDVTVVP 612
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/160 (25%), Positives = 61/160 (38%), Gaps = 15/160 (9%)
Query: 874 WTK-----GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
WTK G A L S +H T+ V + SD + ++D +
Sbjct: 328 WTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF------VRDADPL--- 378
Query: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-R 987
V G P+++ + +V W+ P S +MGYFV + + T W + +
Sbjct: 379 VTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVK 438
Query: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
V+ L G Y FRV N G+S VS A +
Sbjct: 439 ICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAAL 478
Score = 44.3 bits (103), Expect = 7e-04
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
+ + ++ G L L ++ G P P W K D+ +E + ++ S I+ E
Sbjct: 1352 DVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE 1411
Query: 612 DEGRYTIKVTNPVGED----VASIFLQVVDVPD--PPEAVR 646
D G+Y+I + N G + S++ +PD PP+ +
Sbjct: 1412 DSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452
Score = 42.4 bits (98), Expect = 0.003
Identities = 32/101 (31%), Positives = 41/101 (40%), Gaps = 3/101 (2%)
Query: 1041 EHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK---MEIREDPKFLIT 1097
E AP+ L L V S L V+G P P V W K+ + E K+ I
Sbjct: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206
Query: 1098 NYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
+ GV TL I R D TY+ A N G+ + VR
Sbjct: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVR 247
Score = 40.8 bits (94), Expect = 0.007
Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Query: 1059 VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQG-VLTLNIRRPSPFDAGT 1117
++ G + L C V G+P P+V+W KN +I+ F + Q +++ I+ + D+G
Sbjct: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415
Query: 1118 YTCRAVNELG 1127
Y+ N+ G
Sbjct: 1416 YSINIKNKYG 1425
Score = 36.6 bits (83), Expect = 0.14
Identities = 52/259 (20%), Positives = 101/259 (38%), Gaps = 42/259 (16%)
Query: 289 WFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV-- 346
W K+ +EI ++ E VG L + D Y V+V D + FV +P
Sbjct: 943 WCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELE 1002
Query: 347 -LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDG----------VELTREDSFKARY 395
L+ E + + + E+A E+ ++G W++ + RE S +
Sbjct: 1003 RLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIH 1062
Query: 396 RFKKDGKRHI--LIFSDVVQEDRGRYQVITNGGQCEAE-----------LIVEEKQLEVL 442
R K D I ++ E+ G Y V + G+ +++ ++EE + +
Sbjct: 1063 RIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRK 1122
Query: 443 QDIA------------DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVG 490
+ + D+T + + V K + ++ KW K+ V T+ ++
Sbjct: 1123 EFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETE---TLPNLE 1179
Query: 491 R-FHKLVIDDVRPEDEGDY 508
R +L+I + +D G+Y
Sbjct: 1180 RGICELLIPKLSKKDHGEY 1198
Score = 33.9 bits (76), Expect = 0.91
Identities = 40/181 (22%), Positives = 71/181 (39%), Gaps = 10/181 (5%)
Query: 458 FKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV---PDG 514
F C+ + W K+ E+ +R I VG KL + + ED G Y+ DG
Sbjct: 930 FDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989
Query: 515 YALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPP 574
+ S LE + + + P I L SE A + ++R + P
Sbjct: 990 VSSSFVLDPEELERLMALSNEIKNPTIPL-----KSELAYEIFDKGRVRFWLQAEHLSPD 1044
Query: 575 VA--TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF 632
+ + EV + R + +K V++ E+EG YT+++ + + +S+
Sbjct: 1045 ASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLV 1104
Query: 633 L 633
L
Sbjct: 1105 L 1105
Score = 33.9 bits (76), Expect = 0.91
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 10/107 (9%)
Query: 237 DLRGMLKRLKKAKVEVKKSAAFTKK--------LDPAYQVDRGNKIKLMVEI-SDPDLTL 287
DL G A+ + K+AAF +K L + G + L + +PD +
Sbjct: 1317 DLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEV 1376
Query: 288 KWFKNGQEIKPSSKYVFENVGKKRI-LTINKCTLADDAAYEVAVKDE 333
WFKN Q+I+ S + + K + +TI T D Y + +K++
Sbjct: 1377 IWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNK 1423
Score = 31.6 bits (70), Expect = 4.5
Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 4/64 (6%)
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDTVFFVRQAARSDSGEYE 911
G+ LNL G P P+V+W K + S V V + + ++ ++ DSG+Y
Sbjct: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSM-TIKGVTSEDSGKYS 1417
Query: 912 LSVQ 915
++++
Sbjct: 1418 INIK 1421
>gi|140560917 myomesin 1 isoform b [Homo sapiens]
Length = 1589
Score = 127 bits (319), Expect = 6e-29
Identities = 120/472 (25%), Positives = 188/472 (39%), Gaps = 73/472 (15%)
Query: 610 REDEGRYTIKVTNPVGEDVASIFLQVVDV-------PDPPEAVRITSVGEDWAILVWEPP 662
+EDEG YTI+V + S ++ V D P P V+ +D+ I+ W+ P
Sbjct: 474 KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
Query: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
DGG P+ GY +++ + G+ W + N + T +IEG Y RV AVN +G+
Sbjct: 534 AVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIG 593
Query: 723 QPSMNTKPFMPIAPTSE------------------------------PLHLIVEDVTDTT 752
PS ++P + P + P L V + T +
Sbjct: 594 FPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSY 653
Query: 753 TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLPTGARILFRV 811
L W+PP + G GI Y VE C G+E W NTE PV+ F + +L G FRV
Sbjct: 654 VVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRV 712
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPKIR---LPRHLRQTYI-----------RKVGEQ 857
N AG EP+ + + + + PK +P T + VG
Sbjct: 713 RCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYY 772
Query: 858 LNLVVPFQGKPRPQVVWTKGGAPLDTSR--VHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
+ V GK P P+ SR H + +F VR + EY
Sbjct: 773 IEASVAGSGKWEP-----CNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS---- 823
Query: 916 IENMKDTATIRIR-VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFV---QK 971
+D+ I ++ + PP ++ E + + ++ W+ P G +EI GY+V +
Sbjct: 824 ----QDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREV 879
Query: 972 ADKKTMEWFNV-YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSK 1022
D +W + + +S+L Y F+V N+ GL VS+
Sbjct: 880 IDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 931
Score = 116 bits (290), Expect = 1e-25
Identities = 159/719 (22%), Positives = 271/719 (37%), Gaps = 96/719 (13%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDG-YALSLSAKLNFLE 527
+WY+NGV + PSK + G L + EDEG YT V G Y SA + +
Sbjct: 442 QWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRD 501
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
E + P LD + ++++ + +D G P + ++ EV T
Sbjct: 502 ADAEI---EGAPAAPLDVKCLEANKDYIIISWKQPAVD----GGSPILGYFIDKCEVGTD 554
Query: 588 T--------------------EGRTRI-------EKRVDCSSFVIESAQREDEGRYTIKV 620
+ EGR+ I + + S V E D
Sbjct: 555 SWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLK 614
Query: 621 TNPVGEDVASIFLQVVD-----VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
+ P I + + VP PP + +T + +L W+PP G + + Y V
Sbjct: 615 SRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFV 673
Query: 676 ERKKKGSQRWMKLNFEVFTET-TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-- 732
E+ + G++ W ++N E+ ++ + + EG Y RV N+ GV +PS T+ +
Sbjct: 674 EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
Query: 733 -PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
+ P +I TDT+ + W A + GY +E + GS +W P N PV
Sbjct: 734 DKLDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKELVGYYIEASVAGSGKWEPCNNNPV 791
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK----IRLPRHLR 847
+ FT L TG +FRV VN AG SE + ++ + ++ PP I R
Sbjct: 792 KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFR 851
Query: 848 QTYI------------RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH-VRTSDFD 894
+ + G +N G P W + + + + +
Sbjct: 852 DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGK---WREANVKAVSEEAYKISNLKEN 908
Query: 895 TVFFVRQAARSDSGEYELSVQIENMK-DTATIRIRVVEKAGPPINVMVKEVWGTNALVEW 953
V+ + AA + +G S E K + TI + GPP ++ EV + +++W
Sbjct: 909 MVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAV-----PGPPHSLKCSEVRKDSLVLQW 963
Query: 954 QAPKDDGNSEIMGYFV--QKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTEN 1010
+ P G + + GYFV ++A K +W + E ++ V L G Y FRV N
Sbjct: 964 KPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAIN 1023
Query: 1011 ICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCA 1070
G+ ++ + G + + + D V+ S C
Sbjct: 1024 QAGVGKPSDLAGPVVAETRPG---------------TKEVVVNVDDDGVI---SLNFECD 1065
Query: 1071 VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
+ PK + W K+ + + P+ + + + + D G Y+C + G A
Sbjct: 1066 -KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIA 1123
Score = 96.3 bits (238), Expect = 1e-19
Identities = 124/560 (22%), Positives = 216/560 (38%), Gaps = 61/560 (10%)
Query: 616 YTIKVTNPVGEDVASIFLQVVDV------PDPPEAVRITSVGEDWAILVWEPPMYDGGKP 669
+ ++ N G S + ++V P PP + D +L W+ P GG
Sbjct: 809 FRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 868
Query: 670 VTGYLVERKKKGSQ---RWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSM 726
+TGY V ++ +W + N + +E Y+ + + E ++Y+ +V A+N G+ PS
Sbjct: 869 ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 928
Query: 727 NTKPF----MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY--CLEGS 780
++ F IA P L +V + L+W+PP G + GY V+
Sbjct: 929 VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 988
Query: 781 EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKI 840
++W N ++ V+ L G +FRV +N AG +P+ LA PV +AE
Sbjct: 989 DQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV----VAE---- 1040
Query: 841 RLPRHLRQTYIRKVGEQLNLVVPFQ---GKPRPQVVWTKGGAPL-DTSRVHVRTSDFDTV 896
R + + V + + + F+ P+ + W+K D+ R+ V + T
Sbjct: 1041 --TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1098
Query: 897 FFVRQAARSDSGEYELSV------------QIENMKDTATIRIRVVEKAGPPINVMVKEV 944
+ D G Y V E +K + P + + E+
Sbjct: 1099 MTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEI 1158
Query: 945 WGTNALVEW-QAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYY 1003
+ W QA K GN+++ F +K + ++ +RN + + +
Sbjct: 1159 LEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDED-- 1216
Query: 1004 FRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDF-------RMAPKFLTPLID 1056
E G + N + ++ G FK + KE +F + P F+ +
Sbjct: 1217 -----EGTYTFQLQDGKATNHSTVVLVGDVFKKLQ-KEAEFQRQEWIRKQGPHFV-EYLS 1269
Query: 1057 RVVVAGYSAALNCAVRGHPK-PKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
V + L C V K +VW K++ EI D K + G+ TL I S DA
Sbjct: 1270 WEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKD--GICTLLITEFSKKDA 1327
Query: 1116 GTYTCRAVNELGEALAECKL 1135
G Y ++ G+ + KL
Sbjct: 1328 GIYEVILKDDRGKDKSRLKL 1347
Score = 60.5 bits (145), Expect = 9e-09
Identities = 74/303 (24%), Positives = 130/303 (42%), Gaps = 44/303 (14%)
Query: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNG--GQCEAELI 433
++W KD RE S ++ FK DG +LI ++ ++D G Y+VI G+ ++ L
Sbjct: 1293 IVWYKD----EREISVDEKHDFK-DGICTLLI-TEFSKKDAGIYEVILKDDRGKDKSRLK 1346
Query: 434 V-----EEKQLEVLQDIA----DLTVKASEQAV-----FKCEVSDEKVTGKWYKNGVEVR 479
+ +E +EV + IA DL ++++ + + V D KV W NG +R
Sbjct: 1347 LVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVN--WSHNGSAIR 1404
Query: 480 PSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYA-----LSLS------AKLNFLE 527
S R+ G L I++ P D+G Y + DG + LS A F
Sbjct: 1405 YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR 1464
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
+K + ++ ++ G + + + G L L ++ G+PPP +WLK ++ +
Sbjct: 1465 LKQAAIAEKNRARV---LGGLP--DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAS 1519
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ + + F I D G+Y + V N G + + V V P E R+
Sbjct: 1520 DDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDF---TVSVFIPEEEARM 1576
Query: 648 TSV 650
++
Sbjct: 1577 AAL 1579
Score = 55.8 bits (133), Expect = 2e-07
Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 9/168 (5%)
Query: 869 RPQVVWTKGGAPLDTSR-VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRI 927
+P++ W + G PL S+ V S + D G Y + V++ + + +
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
Query: 928 RV------VEKA-GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF 980
V +E A P++V E ++ W+ P DG S I+GYF+ K + T W
Sbjct: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
Query: 981 NVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
+ + V+ LI G Y FRV N G+ VS+ A +
Sbjct: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR---EDPKFLITNYQGVL 1103
AP+F+ V + L+C++ G P+P+V W KN++ I K++I + G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
TL I D Y A+N GE A + V+
Sbjct: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 38.1 bits (87), Expect = 0.048
Identities = 48/217 (22%), Positives = 79/217 (36%), Gaps = 53/217 (24%)
Query: 274 IKLMVEISD-PDLTLKWFKNGQEIKPSS---KYVFENVGKKRILTINKCTLADDAAYEVA 329
+KL I+ P+ + W+KN I + KY+ E+ L IN C D A Y +
Sbjct: 294 VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
Query: 330 VKDEK----CFTELFVKE-----------------PPVLIVTPL---------------- 352
+ K + + VK P VTP
Sbjct: 354 AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
Query: 353 ----EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIF 408
E + + +G RV + E+ ++ W ++GV L+ + + G+R L F
Sbjct: 414 SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLW----SGERATLTF 469
Query: 409 SDVVQEDRGRYQVITNGG----QCEAELIVEEKQLEV 441
S + +ED G Y + G Q A + V + E+
Sbjct: 470 SHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI 506
Score = 37.7 bits (86), Expect = 0.063
Identities = 123/621 (19%), Positives = 220/621 (35%), Gaps = 98/621 (15%)
Query: 68 DAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVV 127
D + A++ G + + I GKW E K+ + ++K S+ + VY + + +
Sbjct: 862 DKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY--QFQVAAMN 919
Query: 128 LGDRGYYRLEVKAKDTCDSCG-FNIDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSG 186
+ G A C C + I V P + + K SG
Sbjct: 920 MAGLG----APSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV-----HSG 970
Query: 187 LLKKREVVEEEKKKKKKDDDDLGIPP----EIWELLKGAKKSEYEKIAFQYGITDLRGML 242
+ K+ K K+D G+ ++ ++G K E F+ + G+
Sbjct: 971 RTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLK--EGVSYVFRVRAINQAGVG 1028
Query: 243 KRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISD--PDLTLKWFKNGQEIKPSS 300
K A V ++ TK++ VD I L E P W K+ + S
Sbjct: 1029 KPSDLAGPVVAETRPGTKEV--VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSP 1086
Query: 301 KYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFV---KEPPVLIVTPLEDQQV 357
+ E+ G K +T + D Y V D ++ +E L+ E +
Sbjct: 1087 RLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFP 1146
Query: 358 FVGDRVEMAVEVSEEGAQVMWM---------KDGVELTREDSFKA-RYRFKKDGKRHIL- 406
V + E+AVE+ E+G WM K ++ F+ +Y+ D I+
Sbjct: 1147 TVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIE 1206
Query: 407 IFSDVVQ-EDRGRYQVITNGG------------------QCEAELIVEE---KQLEVLQD 444
+F + +Q ED G Y G Q EAE +E KQ +
Sbjct: 1207 MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVE 1266
Query: 445 IADLTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKR---------ITISHVGR-- 491
V + KC+V++ K WYK+ E+ ++ + I+ +
Sbjct: 1267 YLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKD 1326
Query: 492 --FHKLVIDDVRPEDEGDYTFVPDGY-----ALSLSAKLNFLEIKVE------------- 531
+++++ D R +D+ V + + + L+ ++K++
Sbjct: 1327 AGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVT 1386
Query: 532 -YVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEG 590
YV + H + + S+ V G ++ L ++ EP P KG V +G
Sbjct: 1387 YYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN---EPTPND---KGKYVMELFDG 1440
Query: 591 RTRIEKRVDCSSFVIESAQRE 611
+T +K VD S + A E
Sbjct: 1441 KTGHQKTVDLSGQAYDEAYAE 1461
Score = 37.7 bits (86), Expect = 0.063
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 58 PDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVY 117
PD V+++ GK + V G P+ + W K + L S F+
Sbjct: 1483 PDVVTIQEGKALNLTCNVWGDPPPE---VSWLKNE-KALASDDHCNLKFEAGR------- 1531
Query: 118 TVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKK 175
T I V D G Y L VK K ++ F + V P ++A +LES K + K
Sbjct: 1532 TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK 1589
Score = 35.8 bits (81), Expect = 0.24
Identities = 37/181 (20%), Positives = 75/181 (41%), Gaps = 10/181 (5%)
Query: 458 FKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYA 516
F+C+ K W K+ V S R+ + G K+ D+ +D G Y+ V D
Sbjct: 1062 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1121
Query: 517 LSLSAKLNFLEIK--VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLR--LDVSITGEP 572
++ S ++ E+K + + + P + + SE A+ ++ ++R +
Sbjct: 1122 IASSYLIDEEELKRLLALSHEHKFPTVPV-----KSELAVEILEKGQVRFWMQAEKLSGN 1176
Query: 573 PPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF 632
V E+F + + I++ +E Q EDEG YT ++ + + +++
Sbjct: 1177 AKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVV 1236
Query: 633 L 633
L
Sbjct: 1237 L 1237
Score = 35.4 bits (80), Expect = 0.31
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQG-VLTLNIRRPSPFDAGTYTC 1120
G + L C V G P P+V W+KN+ + D + G I S D+G Y
Sbjct: 1491 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1550
Query: 1121 RAVNELGEALAECKLEVRVPQ 1141
N+ G ++ + V +P+
Sbjct: 1551 VVKNKYGSETSDFTVSVFIPE 1571
Score = 34.7 bits (78), Expect = 0.53
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 814 VNIAGRSEPATLAQPVTIRE--IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
V+++G++ A+ +++ IAE + R+ L + G+ LNL G P P+
Sbjct: 1448 VDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPE 1507
Query: 872 VVWTKGGAPL-DTSRVHVRTSDFDTVFF-VRQAARSDSGEYELSVQIENMKDTATIRIRV 929
V W K L +++ T +F + + +DSG+Y L V+ + +T+ + V
Sbjct: 1508 VSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1567
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/67 (29%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 562 LRLDVSITGEPPPVATWLKGDEVFT--TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619
++L SI G P P TW K G+ IE R + I ED +Y
Sbjct: 294 VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
Query: 620 VTNPVGE 626
N GE
Sbjct: 354 AMNVKGE 360
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 125 bits (314), Expect = 2e-28
Identities = 149/593 (25%), Positives = 226/593 (38%), Gaps = 99/593 (16%)
Query: 269 DRGNKIKLMVEISDPD--LTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G+ +L ++SD + ++W K G E+ KY + G R L I++ D Y
Sbjct: 4080 ETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVEL 385
+K L V EP V IV L D +V + VE + EVS GA V W G+ L
Sbjct: 4140 ACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPL 4199
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+ + R DG+ H L V ED G A+L V ++ +L+ +
Sbjct: 4200 QSNEVTEVAVR---DGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPL 4256
Query: 446 ADLTVKASEQAVFKCEVSDEK-VTGKWYKNGVEVRPSKRITIS-HVGRFHKLVIDDVRPE 503
D+ + + A F+C +S +W GV ++ ++ I+ G H L + V E
Sbjct: 4257 QDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316
Query: 504 DEGDYTF----VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK----------- 548
D G +F L ++AK N + +E V E + +C
Sbjct: 4317 DAGTVSFHVGTCSSEAQLKVTAK-NTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLL 4375
Query: 549 ------TSENAIVVVAGNKLRLDVSITGEPPPVA---TWLKGDEV---FTTTEG------ 590
TSENA VV N LR + + P + T+L GD V F T G
Sbjct: 4376 DDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEIL 4435
Query: 591 --------RTRIEKRVDC-----------SSFVIESAQREDEGRYTI------------- 618
R + C S ++ +A + D+ +T+
Sbjct: 4436 EPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRS 4495
Query: 619 -------KVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
+VT + VAS L V+ +PDPPE + + L W PM DGG +
Sbjct: 4496 AQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLC 4555
Query: 672 GYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP------- 724
GY VE K+ + +W +L E+ + G Y RV AV +G +P
Sbjct: 4556 GYRVEVKEGATGQW-RLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTV 4614
Query: 725 ----SMNTKPFMPIAPTS------EPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P AP S E + L +E V + + + RI GG
Sbjct: 4615 RLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGG 4667
Score = 105 bits (263), Expect = 2e-22
Identities = 71/283 (25%), Positives = 126/283 (44%), Gaps = 12/283 (4%)
Query: 269 DRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV 328
+ G + +S D+ + WF++G ++PS K+ G LTI+ L D V
Sbjct: 1911 EEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 329 AVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTRE 388
+ L V+E PVL LE Q V V + VE++ ++ W ++ L
Sbjct: 1971 EAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPG 2030
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADL 448
+ + +G RH L+ +V DRG + T + +A+L VE +Q+ +++ + +
Sbjct: 2031 KNVEIH----AEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAV 2086
Query: 449 TVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
+ A + ++S V G W ++G+ + ++ G H L + +RPED G
Sbjct: 2087 EAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLM 2146
Query: 509 TFVPDGYALSLSAKLNFLEIKVEY------VPKQEPPKIHLDC 545
F +G + SA+L E+ V + V E K+ L+C
Sbjct: 2147 VFKAEG--VHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLEC 2187
Score = 101 bits (251), Expect = 5e-21
Identities = 74/271 (27%), Positives = 119/271 (43%), Gaps = 8/271 (2%)
Query: 242 LKRLKKAKVEVK-KSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSS 300
LK A++EV+ K F K LD +RG + L E+SDP+ + W K+G ++ PS
Sbjct: 2632 LKVSTSARLEVRVKPVVFLKALDDLSAEERGT-LALQCEVSDPEAHVVWRKDGVQLGPSD 2690
Query: 301 KYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVG 360
KY F + R L ++ + D Y V E+ + V + V I L+ +V G
Sbjct: 2691 KYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEG 2750
Query: 361 DRVEMAVEVSEEGAQ--VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGR 418
+ +S E A MW G + F+A + G+++IL+ + D G
Sbjct: 2751 ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQA----TRQGRKYILVVREAAPSDAGE 2806
Query: 419 YQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEV 478
G +A LIV E+ +++ + D V E +CE+S W K+ +
Sbjct: 2807 VVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAI 2866
Query: 479 RPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
R S++ + G LVI +D G+YT
Sbjct: 2867 RKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897
Score = 99.8 bits (247), Expect = 1e-20
Identities = 77/316 (24%), Positives = 135/316 (42%), Gaps = 26/316 (8%)
Query: 227 EKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT 286
++++F IT+ +G+ + + EV Q + G L E++ P
Sbjct: 1151 QRVSFHLHITEPKGVFAKEQSVHNEV--------------QAEAGTTAMLSCEVAQPQTE 1196
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
+ W+K+G+++ SSK E G R L + + AD Y ++ +L + EP
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKA 1256
Query: 347 LIVTPL---EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
+ + + G ++ EV++ +V W KDG +L S ++ R + G
Sbjct: 1257 VFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKL----SSSSKVRIEAAGCM 1312
Query: 404 HILIFSDVVQEDRGRYQVITNGGQCEAELIVEE-KQLEVLQDIADLTVKASEQAV--FKC 460
L+ Q D G Y G + L V E K + + +A V+A A+ C
Sbjct: 1313 RQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSC 1372
Query: 461 EVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
EV+ + WYK+G ++ S ++ + VG +LV+ D G+Y+ G LS S
Sbjct: 1373 EVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFS 1432
Query: 521 AKLNFLEIKVEYVPKQ 536
L+ E KV + +Q
Sbjct: 1433 --LDVAEPKVVFAKEQ 1446
Score = 98.2 bits (243), Expect = 4e-20
Identities = 125/585 (21%), Positives = 212/585 (36%), Gaps = 64/585 (10%)
Query: 49 EPTGVFLKKP---DSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFS 105
EP VF K+ + E G A + +V + + W+K G + S
Sbjct: 885 EPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTE----VTWYK---------DGKKLS 931
Query: 106 FKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSL 165
+ T L + + D G Y E + F++DV+ P+
Sbjct: 932 SSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFHLDVKEPKV------- 980
Query: 166 ESFKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSE 225
F + S+ E S L + + KD L ++ KG ++
Sbjct: 981 -VFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRR-- 1037
Query: 226 YEKIAFQYGITDL-------RGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMV 278
+ Q G TD RG + E K A + + Q + G L
Sbjct: 1038 -RLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSC 1096
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E++ + W+K+G+++ SSK E G R L + + AD Y ++
Sbjct: 1097 EVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFH 1156
Query: 339 LFVKEPPVLIVTPLE---DQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARY 395
L + EP + + Q G ++ EV++ +V W KDG +L S ++
Sbjct: 1157 LHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKL----SSSSKV 1212
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAEL-IVEEKQLEVLQDIA--DLTVKA 452
R + G L+ V + D G Y G + +L I E K + + + ++ +A
Sbjct: 1213 RMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEA 1272
Query: 453 SEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVP 512
A CEV+ + WYK+G ++ S ++ I G +LV+ D G+YT
Sbjct: 1273 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 513 DGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEP 572
G LS L+ E K + +Q + + AG L +
Sbjct: 1333 GGQRLSF--HLDVSEPKAVFAKEQ------------LAHRKVQAEAGAIATLSCEVAQAQ 1378
Query: 573 PPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
V TW K D ++ + R+E V++ A + D G Y+
Sbjct: 1379 TEV-TWYK-DGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYS 1421
Score = 97.8 bits (242), Expect = 5e-20
Identities = 82/360 (22%), Positives = 140/360 (38%), Gaps = 25/360 (6%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
Q G L E++ + W+K+G+++ SSK E VG R L + + A Y
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEY 1512
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPL---EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGV 383
++ L V EP + + Q G ++ EV++ +V W KDG
Sbjct: 1513 SCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGK 1572
Query: 384 ELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQ 443
+L S ++ R + G L+ + Q D G Y + L V E ++ +
Sbjct: 1573 KL----SSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAK 1628
Query: 444 DIA---DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
+ ++ +A A CEV+ + WYK+G ++ S ++ + VG +LV+
Sbjct: 1629 EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQA 1688
Query: 501 RPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
D G+Y+ G LS + LE ++ P + P +VV
Sbjct: 1689 GQADAGEYSCEAGGQRLSFRLHVAELEPQISERPCRREP--------------LVVKEHE 1734
Query: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
+ L ++ TWLK D V R + D + + AQ D Y+ +V
Sbjct: 1735 DIILTATLATPSAATVTWLK-DGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRV 1793
Score = 97.8 bits (242), Expect = 5e-20
Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 4/223 (1%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
++W+K+ + PS K+ G+ L I + AD Y TE+ V+ V
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREV 2558
Query: 347 LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
+ PL+D + + E+S E +V W +G+ L DSF + G+RH L
Sbjct: 2559 TVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYN-DSF---HEISHKGRRHTL 2614
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
+ + + D G + + A L V K + L+ + DL+ + +CEVSD +
Sbjct: 2615 VLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPE 2674
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
W K+GV++ PS + H LV+ DV PED G YT
Sbjct: 2675 AHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYT 2717
Score = 96.7 bits (239), Expect = 1e-19
Identities = 74/270 (27%), Positives = 114/270 (42%), Gaps = 20/270 (7%)
Query: 240 GMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPS 299
G+ KRLK +V +S +F L SDP + W G+ + S
Sbjct: 2737 GITKRLKTMEVLEGESCSFECVLSHE-------------SASDPAM---WTVGGKTVGSS 2780
Query: 300 SKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFV 359
S++ G+K IL + + +D +V+ L V+E P I+ PLEDQ V
Sbjct: 2781 SRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAP 2840
Query: 360 GDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY 419
G+ VE+ E+S G V W+KD + + +Y +G +L+ +D G Y
Sbjct: 2841 GEDVELRCELSRAGTPVHWLKDRKAIRKSQ----KYDVVCEGTMAMLVIRGASLKDAGEY 2896
Query: 420 QVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVR 479
+ A L VEEK +++ +L V+ AVF C+ T W K +E+R
Sbjct: 2897 TCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELR 2956
Query: 480 PSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
S + S G +L I + D YT
Sbjct: 2957 ASGKHQPSQEGLTLRLTISALEKADSDTYT 2986
Score = 92.8 bits (229), Expect = 2e-18
Identities = 82/379 (21%), Positives = 148/379 (39%), Gaps = 29/379 (7%)
Query: 249 KVEVKKSAAFTKKLDPAYQVDR-----GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYV 303
++EV+ + T PA + +L+ E+SD + W K+G+ + P KY
Sbjct: 694 RMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYE 753
Query: 304 FENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQV--FVGD 361
+ +R+L + D YE + + +L V+ + + V G
Sbjct: 754 VQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAVAGG 813
Query: 362 RVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
+ E SE V W KDG+EL R+ + G RH L+ + V ++D G Y
Sbjct: 814 PAQFECETSEAHVHVHWYKDGMELGHSGE---RFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 422 ITNGGQCEAELIVEEKQLEVLQD---IADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEV 478
+ L V E ++ ++ L +A A CEV+ + WYK+G ++
Sbjct: 871 RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKL 930
Query: 479 RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEP 538
S ++ + G +LV+ D G+Y+ G LS L+ E KV + Q
Sbjct: 931 SSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSF--HLDVKEPKVVFAKDQ-- 986
Query: 539 PKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRV 598
+ + + AG L + V + G ++ ++ + +E +
Sbjct: 987 ----------VAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSL--KVHVEAKG 1034
Query: 599 DCSSFVIESAQREDEGRYT 617
V++ A + D G Y+
Sbjct: 1035 CRRRLVVQQAGKTDAGDYS 1053
Score = 92.4 bits (228), Expect = 2e-18
Identities = 91/417 (21%), Positives = 162/417 (38%), Gaps = 44/417 (10%)
Query: 227 EKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT 286
++++FQ IT+ + + + + EV+ A G L E++
Sbjct: 1243 QRVSFQLHITEPKAVFAKEQLVHNEVRTEA--------------GASATLSCEVAQAQTE 1288
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
+ W+K+G+++ SSK E G R L + + AD Y ++ L V EP
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKA 1348
Query: 347 LIVTPL---EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
+ Q G ++ EV++ +V W KDG +L S ++ R + G
Sbjct: 1349 VFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKL----SSSSKVRMEAVGCT 1404
Query: 404 HILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA---DLTVKASEQAVFKC 460
L+ Q D G Y G + L V E ++ ++ ++ +A C
Sbjct: 1405 RRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSC 1464
Query: 461 EVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
EV+ + WYK+G ++ S ++ + VG +LV+ G+Y+ + + LS
Sbjct: 1465 EVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSC--EAGSQRLS 1522
Query: 521 AKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK 580
L+ E K + K++P + TS VA + TW K
Sbjct: 1523 FHLHVAEPKAVFA-KEQPASREVQAEAGTSATLSCEVA------------QAQTEVTWYK 1569
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVD 637
D ++ + R+E V++ A + D G Y+ K G+ S L V +
Sbjct: 1570 -DGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCK----AGDQRLSFHLHVAE 1621
Score = 90.5 bits (223), Expect = 8e-18
Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 7/257 (2%)
Query: 286 TLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPP 345
T+ W K+G EI+ S ++ + G LT++ + D A Y V E + V+E
Sbjct: 1749 TVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVA 1808
Query: 346 VLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHI 405
LE +G V +A E+S A+V+W +L R++ +G
Sbjct: 1809 AKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLR----VGKRFQMVAEGPVRS 1864
Query: 406 LIFSDVVQEDRGRYQVITNGGQCEAELIVE-EKQLEVLQDIADLTVKASEQAVFKCEVSD 464
L + ED G Y + A+L V + ++ + ++ + + +A F+C VS
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP 1924
Query: 465 EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLN 524
V W+++G ++PS++ IS G H L I D+ ED G T +G S SA L
Sbjct: 1925 SDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG--ASSSAALR 1982
Query: 525 FLEIKVEYVPKQEPPKI 541
E V + K EP +
Sbjct: 1983 VREAPVLFKKKLEPQTV 1999
Score = 90.5 bits (223), Expect = 8e-18
Identities = 83/345 (24%), Positives = 136/345 (39%), Gaps = 27/345 (7%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E+S D ++W NG + S + + G++ L + AD +
Sbjct: 2580 ELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSAR 2639
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
L V+ PV+ + L+D + + EVS+ A V+W KDGV+L D +Y F
Sbjct: 2640 LEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSD----KYDFL 2695
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
L+ DV ED G Y + A + V + + + + + + V E F
Sbjct: 2696 HTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSF 2755
Query: 459 KCEVSDEKVT--GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYA 516
+C +S E + W G V S R + GR + LV+ + P D G+ F G
Sbjct: 2756 ECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRG-- 2813
Query: 517 LSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN-KLRLDVSITGEPPPV 575
L K + ++ P I K E+ V + +LR ++S G P
Sbjct: 2814 ---------LTSKASLIVRERPAAII-----KPLEDQWVAPGEDVELRCELSRAGTP--- 2856
Query: 576 ATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
WLK + ++ + + + VI A +D G YT +V
Sbjct: 2857 VHWLKDRKAIRKSQ-KYDVVCEGTMAMLVIRGASLKDAGEYTCEV 2900
Score = 90.1 bits (222), Expect = 1e-17
Identities = 66/266 (24%), Positives = 111/266 (41%), Gaps = 6/266 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
Q + G+ L E+S+P T+ W K G +++ + + G L + D Y
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
+ L V PV + L+ Q+V G + E+S GA V W K ++L
Sbjct: 3960 TCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLF 4019
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
A+Y+ +DG L+ V QED G Y T Q A L V + + +
Sbjct: 4020 P----CAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQ 4075
Query: 447 DLTVKASEQAVFKCEVSDEK--VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPED 504
L + + A C++SD + +W K GVE+ + + G +L+I + +D
Sbjct: 4076 SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKD 4135
Query: 505 EGDYTFVPDGYALSLSAKLNFLEIKV 530
G+Y V G + S ++ E+ +
Sbjct: 4136 TGEYACVTGGQKTAASLRVTEPEVTI 4161
Score = 89.7 bits (221), Expect = 1e-17
Identities = 64/251 (25%), Positives = 104/251 (41%), Gaps = 5/251 (1%)
Query: 258 FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINK 317
F KKL+P V+ + + L VE++ P L+W +N + P G + L ++
Sbjct: 1990 FKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHN 2048
Query: 318 CTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM 377
AD + D+K +L V+ V +V L+ + M V++S
Sbjct: 2049 VGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGS 2108
Query: 378 WMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
W +DG+ + + R G H L S + ED G G A L+V E
Sbjct: 2109 WTRDGLRFQQGPTCHLAVR----GPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTEL 2164
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVI 497
+ + + D+ E+ +CE+S V +W K+GVE+R K + I+ G L I
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224
Query: 498 DDVRPEDEGDY 508
D+G Y
Sbjct: 2225 YRCEFADQGVY 2235
Score = 89.0 bits (219), Expect = 2e-17
Identities = 63/263 (23%), Positives = 103/263 (39%), Gaps = 31/263 (11%)
Query: 278 VEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFT 337
V++S D+ W ++G + G LT++ D +
Sbjct: 2098 VQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSA 2157
Query: 338 ELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKAR--- 394
L V E PV PL+D ++V + E+S V W+KDGVEL +
Sbjct: 2158 RLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQG 2217
Query: 395 -------YR---------------------FKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
YR K G+ + LI+ V+ ED G Q +
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENA 2277
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
+ A+L V+E + +++ + D + V +C+VS +W+K E++P + +
Sbjct: 2278 ESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYEL 2337
Query: 487 SHVGRFHKLVIDDVRPEDEGDYT 509
G + KL+I DV EDE YT
Sbjct: 2338 VSDGLYRKLIISDVHAEDEDTYT 2360
Score = 87.8 bits (216), Expect = 5e-17
Identities = 89/365 (24%), Positives = 156/365 (42%), Gaps = 36/365 (9%)
Query: 265 AYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDA 324
A Q G ++ V+++ +WF +GQ +K SS Y + LTI + +
Sbjct: 621 AVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHG 679
Query: 325 A--------YEVAVKDE-KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ 375
A E +++ E + L +PP + + + ++ E+S++ A
Sbjct: 680 AQLKFVANGIESSIRMEVRAAPGLTANKPP---AAAAREVLARLHEEAQLLAELSDQAAA 736
Query: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVE 435
V W+KDG R S +Y + R +L+ DV ++D G Y+ ++ GG+ +L V+
Sbjct: 737 VTWLKDG----RTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQ 792
Query: 436 EKQLEVLQDIADLTVK--ASEQAVFKCEVSDEKVTGKWYKNGVEVRPS-KRITISHVGRF 492
+ +D+A V A A F+CE S+ V WYK+G+E+ S +R VG
Sbjct: 793 GLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTR 852
Query: 493 HKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSEN 552
H+LV V +DEG Y S ++ E V++ + PK+ + + +
Sbjct: 853 HRLVAATVTRQDEGTY-----------SCRVG--EDSVDFRLRVSEPKV-VFAKEQLARR 898
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
+ AG L + V TW K D ++ + +E V++ A + D
Sbjct: 899 KLQAEAGASATLSCEVAQAQTEV-TWYK-DGKKLSSSSKVCMEATGCTRRLVVQQAGQAD 956
Query: 613 EGRYT 617
G Y+
Sbjct: 957 AGEYS 961
Score = 79.0 bits (193), Expect = 2e-14
Identities = 84/388 (21%), Positives = 144/388 (37%), Gaps = 28/388 (7%)
Query: 253 KKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRI 312
+K+ FT++L ++G + + P T+ W K E++ S K+ G
Sbjct: 2913 EKANCFTEELTNLQVEEKGTAV-FTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLR 2971
Query: 313 LTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEE 372
LTI+ AD Y + + +L V+ V I+ LED V G +S
Sbjct: 2972 LTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPA 3031
Query: 373 GAQ-VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAE 431
+ V W D L + + + G H+L + +D G + A
Sbjct: 3032 NYEPVHWFLDKTPLHANELNEID---AQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAA 3088
Query: 432 LIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGR 491
L V EK +++ D T+ E CE S + W K+G +R S R +SH G
Sbjct: 3089 LRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGH 3148
Query: 492 FHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSE 551
+L+I +D G Y G S +++ ++ + K
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD--------------- 3193
Query: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
+ V+ G L ++ PV W G+ V + + + + V+ + + +
Sbjct: 3194 --LEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGD-KYSLRQEGAMLELVVRNLRPQ 3249
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVP 639
D GRY+ G+ S L V +P
Sbjct: 3250 DSGRYSCS----FGDQTTSATLTVTALP 3273
Score = 77.8 bits (190), Expect = 5e-14
Identities = 133/578 (23%), Positives = 216/578 (37%), Gaps = 101/578 (17%)
Query: 371 EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVV-----------QEDRGRY 419
E + +W KDG +T +G+RH+ ++ D Q DRG Y
Sbjct: 264 EPKPETVWKKDGQLVT-------------EGRRHV-VYEDAQENFVLKILFCKQSDRGLY 309
Query: 420 QVITNG--GQCEAEL--IVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNG 475
+ GQ + + +V E + + + DL V+ E A F CEV W+K
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEE 369
Query: 476 VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVP 534
+ S + I G +L + +V +D+ Y P+G E+ V+
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG-------SRTVAELAVQGNL 422
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
++ P+ KT+ V G+ V + PV WL+ E GR I
Sbjct: 423 LRKLPR-------KTA-----VRVGDTAMFCVELAVPVGPVH-WLRNQEE-VVAGGRVAI 468
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ I ED G+ + + PP + + E
Sbjct: 469 SAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESS 528
Query: 655 AILVWEPPMYDGGKPVT--GYLVERKKKGSQRWMKLNFEVFTETTYEST--KMIEGILYE 710
IL W PP + G +PVT GYLVE+KK G+ W++ + E T E T + E ++
Sbjct: 529 VILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCH-EAEWVATPELTVADVAEEGNFQ 586
Query: 711 MRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGA--GGI 768
RV A+N+ G S P++ T +HL + T P + A GG
Sbjct: 587 FRVSALNSFGQS-------PYLEFPGT---VHLAPKLAVRT-------PLKAVQAVEGGE 629
Query: 769 DGYLVEYCLEGSEEW------VPANTEPVERCG-----FTVKNLPT---GARILFRVVGV 814
+ V+ + + EW + A++ C T++ +P GA++ F G+
Sbjct: 630 VTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGI 689
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
+ R E +R + P + + ++ E+ L+ + V W
Sbjct: 690 ESSIRME---------VRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQ-AAAVTW 739
Query: 875 TKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYE 911
K G L + V+ S V VR AR D+G YE
Sbjct: 740 LKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYE 777
Score = 77.8 bits (190), Expect = 5e-14
Identities = 178/900 (19%), Positives = 326/900 (36%), Gaps = 133/900 (14%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G+ L E+S ++W K + ++ ++ G + L I + D Y
Sbjct: 3724 EATEGDTATLWCELSKA-APVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEY 3782
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
E+ L V+ P + +++Q+ G + E+S+ A V W K L
Sbjct: 3783 SCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSK-AAPVEWRKGSETLR 3841
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
D RY ++DG R L + D G Y + + A L V Q + +
Sbjct: 3842 GGD----RYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQ 3897
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
L + A +CE+S+ T W K G++++ + R G +LV+ D++ ED G
Sbjct: 3898 SLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTG 3957
Query: 507 DYTFVPDGYALS-----LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNK 561
+YT A S +A + FL ++++ E HL C
Sbjct: 3958 EYTCTCGSQATSATLTVTAAPVRFLR-ELQHQEVDEGGTAHLCC---------------- 4000
Query: 562 LRLDVSITGEPPPVATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
++S G W KG ++F + ++ + + ++ ++ED G YT
Sbjct: 4001 ---ELSRAGAS---VEWRKGSLQLFPC--AKYQMVQDGAAAELLVRGVEQEDAGDYTCDT 4052
Query: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
+ + +AS+ V VP P R+ S+ ++ + + L + +
Sbjct: 4053 GHT--QSMASL---SVRVPRPKFKTRLQSLEQETGDIA----------RLCCQLSDAESG 4097
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAP--TS 738
+W+K E+ YE +G E+ + + A + + T A +
Sbjct: 4098 AVVQWLKEGVELHAGPKYEMRS--QGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVT 4155
Query: 739 EPLHLIVEDVTDTTTTLKWR-----PPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVER 793
EP IV + D T +R GA G V++CL+G TE R
Sbjct: 4156 EPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATG-----VQWCLQGLPLQSNEVTEVAVR 4210
Query: 794 CG----FTVKNL-PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQ 848
G +K + P A + +G N A ++ A VTI E + ++
Sbjct: 4211 DGRIHTLRLKGVTPEDAGTVSFHLG-NHASSAQLTVRAPEVTILEPLQDVQL-------- 4261
Query: 849 TYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF--VRQAARSD 906
G+ + + W GG PL + ++ T + T+ + + D
Sbjct: 4262 ----SEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLED 4317
Query: 907 SGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966
+G +S + A +++ N +V+ + AL +G +
Sbjct: 4318 AG--TVSFHVGTCSSEAQLKVTAK-------NTVVRGLENVEAL--------EGGEALFE 4360
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI-----CGLSDSPGVS 1021
+ + + W + + HTS + N + +N+ C ++ G
Sbjct: 4361 CQLSQPEVAAHTWL-LDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDM 4419
Query: 1022 KNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAV-RGHPKPKVV 1080
+A + G +R+ + L PL + V AG A C + P +
Sbjct: 4420 VTSAFLTVRG------------WRL--EILEPLKNAAVRAGAQACFTCTLSEAVPVGEAS 4465
Query: 1081 WMKNKMEIR-EDPKFLITNYQGVLTLNIRRPSPFDAG--TYTCRAVNELGEALAECKLEV 1137
W N ++ +D + +T L +R P AG T+ CR +A+A +L V
Sbjct: 4466 WYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR------DAVASARLTV 4519
Score = 75.1 bits (183), Expect = 4e-13
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 7/259 (2%)
Query: 250 VEVKKSAA-FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVG 308
V+V++ AA F + L+P + G + L E+S + W +++ ++ G
Sbjct: 1802 VQVEEVAAKFCRLLEPVCG-ELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEG 1860
Query: 309 KKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVL-IVTPLEDQQVFVGDRVEMAV 367
R LT+ D Y +D+ +L V P V+ ++ L G
Sbjct: 1861 PVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQC 1920
Query: 368 EVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQ 427
VS V+W +DG L + F + G H L SD+V ED G+ V G
Sbjct: 1921 VVSPSDVAVVWFRDGALLQPSEKF----AISQSGASHSLTISDLVLEDAGQITVEAEGAS 1976
Query: 428 CEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITIS 487
A L V E + + + TV+ + E++ +W +N + P K + I
Sbjct: 1977 SSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIH 2036
Query: 488 HVGRFHKLVIDDVRPEDEG 506
G H+LV+ +V D G
Sbjct: 2037 AEGARHRLVLHNVGFADRG 2055
Score = 70.5 bits (171), Expect = 9e-12
Identities = 79/353 (22%), Positives = 134/353 (37%), Gaps = 29/353 (8%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
++W+K + ++ ++ G + L I D Y E+ L V+ P
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPS 3714
Query: 347 LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
+ L +++ GD + E+S+ A V W K G E R+ R+ ++DG R L
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSK-AAPVEWRK-GHETLRDGD---RHSLRQDGSRCEL 3769
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
+ D G Y + + A L V ++D+ + + AV +CE+S +
Sbjct: 3770 QIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELS-KA 3828
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
+W K +R R ++ G +L I + D G+Y+ V S + L
Sbjct: 3829 APVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSAT-----L 3883
Query: 527 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 586
++ +EP + G T+ L+ ++S EP W KG +
Sbjct: 3884 TVRAPQPVFREPLQSLQAEEGSTAT----------LQCELS---EPTATVVWSKGG-LQL 3929
Query: 587 TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVP 639
GR + + V++ QRED G YT G S L V P
Sbjct: 3930 QANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGSQATSATLTVTAAP 3978
Score = 68.2 bits (165), Expect = 4e-11
Identities = 79/311 (25%), Positives = 116/311 (37%), Gaps = 49/311 (15%)
Query: 375 QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITN---------- 424
QV W KD + AR+R +DG + L D+ D G+Y
Sbjct: 40 QVSWEKDQQPVAAG----ARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95
Query: 425 GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRP--S 481
G Q +AE E+ L + V+ +A F+C V + W K+G +
Sbjct: 96 GLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDG 155
Query: 482 KRITISHVGRFHKLVIDDVRPEDEGDY---------------TFVPDGYAL--------S 518
R+ + +G L I RP D G Y V D A S
Sbjct: 156 PRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTS 215
Query: 519 LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW 578
+A L L+ + E + + P T V G RL +TGEP P W
Sbjct: 216 TAALLAHLQRRREAMRAEGAPA----SPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVW 271
Query: 579 LKGDEVFTTTEGRTRIEKRVDCSSFVIE--SAQREDEGRYTIKVTNPVGEDVASIFLQVV 636
K ++ TEGR + +FV++ ++ D G YT +N VG+ +S+ L VV
Sbjct: 272 KKDGQL--VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVV 328
Query: 637 DVPDPPEAVRI 647
P P R+
Sbjct: 329 REPAVPFKKRL 339
Score = 67.0 bits (162), Expect = 1e-10
Identities = 53/234 (22%), Positives = 91/234 (38%), Gaps = 5/234 (2%)
Query: 276 LMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKC 335
L ++S ++WFK QE++P KY + G R L I+ D+ Y D K
Sbjct: 2309 LECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKT 2368
Query: 336 FTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKAR 394
+ FV+E + IV L+D V E S + W+ L
Sbjct: 2369 SAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVL----QAGGN 2424
Query: 395 YRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASE 454
+++G H L+ G + A L+V + + + + + T + +
Sbjct: 2425 VGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQ 2484
Query: 455 QAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
V C+ +WYK+ + PS++ +S G+ +L I + P D G Y
Sbjct: 2485 SVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Score = 64.7 bits (156), Expect = 5e-10
Identities = 81/380 (21%), Positives = 143/380 (37%), Gaps = 31/380 (8%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
++W K + ++ +Y G K L I +AD Y E+ L V+ P+
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPI 3626
Query: 347 LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
L +++ G + E+S+ A V W K G E R+ R+ ++DG R L
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKM-APVEWWK-GHETLRDGD---RHSLRQDGARCEL 3681
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
+V ED G Y + + A L V + ++ + + + A CE+S +
Sbjct: 3682 QIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELS-KA 3740
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
+W K +R R ++ G +L I + D G+Y+ V S + + L
Sbjct: 3741 APVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRAL 3800
Query: 527 EIK-VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
+ +E V QE E A V+ + L + E + L+G + +
Sbjct: 3801 PARFIEDVKNQE-----------AREGATAVL---QCELSKAAPVEWRKGSETLRGGDRY 3846
Query: 586 TTTEGRTRIEKRV------DCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVP 639
+ + TR E ++ D + Q T++ PV + LQ +
Sbjct: 3847 SLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREP----LQSLQAE 3902
Query: 640 DPPEAVRITSVGEDWAILVW 659
+ A + E A +VW
Sbjct: 3903 EGSTATLQCELSEPTATVVW 3922
Score = 63.9 bits (154), Expect = 8e-10
Identities = 144/692 (20%), Positives = 237/692 (34%), Gaps = 82/692 (11%)
Query: 251 EVKKSAAFTKKLDPAYQVDR--------GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKY 302
E + SA+ T + PA+ + R G L E+S ++W K + ++ ++
Sbjct: 3348 EERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELSKA-APVEWRKGRESLRDGDRH 3406
Query: 303 VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDR 362
G L I +AD Y +E+ L VK P L +++ G
Sbjct: 3407 SLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGAT 3466
Query: 363 VEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI 422
+ E+S+ A V W K L D RY +++G R L + D G Y +
Sbjct: 3467 AMLWCELSKV-APVEWRKGPENLRDGD----RYILRQEGTRCELQICGLAMADAGEYLCV 3521
Query: 423 TNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSK 482
+ A L + ++D+ + + AV +CE++ +W K +R
Sbjct: 3522 CGQERTSATLTIRALPARFIEDVKNQEAREGATAVLQCELNSAAPV-EWRKGSETLRDGD 3580
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
R ++ G +L I + D G+Y+ V S + L IK + E
Sbjct: 3581 RYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNE----- 3635
Query: 543 LDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSS 602
+ +E A V LR ++S + PV W KG E + + + C
Sbjct: 3636 -----EATEGATAV-----LRCELS---KMAPV-EWWKGHETLRDGDRHSLRQDGARC-E 3680
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDP-PEAVRITSVGEDWAILVWEP 661
I ED G Y G++ S L V +P E +R E +W
Sbjct: 3681 LQIRGLVAEDAGEYLCM----CGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLW-- 3734
Query: 662 PMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGV 721
E K W K E + S + +G E+++ + +
Sbjct: 3735 -------------CELSKAAPVEWRK-GHETLRDGDRHSLRQ-DGSRCELQIRGLAVVDA 3779
Query: 722 SQPSM---NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLE 778
+ S + + + P I EDV + R GA + E
Sbjct: 3780 GEYSCVCGQERTSATLTVRALPARFI-EDVKNQEA--------REGATAV--LQCELSKA 3828
Query: 779 GSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA----QPVTIREI 834
EW R G G R ++ G+++A E + + T+
Sbjct: 3829 APVEW--RKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVR 3886
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDF 893
A P R P Q+ + G L +P VVW+KGG L + R R
Sbjct: 3887 APQPVFREP---LQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGC 3942
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATI 925
++ R D+GEY + + T T+
Sbjct: 3943 TAELVLQDLQREDTGEYTCTCGSQATSATLTV 3974
Score = 61.2 bits (147), Expect = 5e-09
Identities = 96/440 (21%), Positives = 152/440 (34%), Gaps = 45/440 (10%)
Query: 42 DQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSG 101
D E FL +P S+ V G +A +V G +P + W K LG G
Sbjct: 100 DAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSP---RPAVSWSKDG-RRLGEPDG 155
Query: 102 ARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDAS 161
R +E +++ L I D G Y + + S + V++ D +
Sbjct: 156 PRVRVEELGEASA------LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTA 209
Query: 162 GQSLESF--------KRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPE 213
+ S +R +++ A S + V E + + P
Sbjct: 210 SRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPET 269
Query: 214 IWE-----LLKGAKKSEYE--------KIAF-------QYGITDLRGMLKRLKKAKVEVK 253
+W+ + +G + YE KI F Y T + + V V+
Sbjct: 270 VWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329
Query: 254 KSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRIL 313
+ A KK +V + E+ P WFK + S+KY E G +R L
Sbjct: 330 EPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRL 389
Query: 314 TINKCTLADDAAYEVAVKD-EKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEE 372
T+ + DDA Y + + EL V+ L+ V VGD VE++
Sbjct: 390 TVRNVSADDDAVYICETPEGSRTVAELAVQGN--LLRKLPRKTAVRVGDTAMFCVELAVP 447
Query: 373 GAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAEL 432
V W+++ E+ R +G RH L S ED G+ + Q +
Sbjct: 448 VGPVHWLRNQEEVVA----GGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQF 503
Query: 433 IVEEKQLEVLQDIADLTVKA 452
V + LQ D VKA
Sbjct: 504 CVSAPRKPPLQPPVDPVVKA 523
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/94 (36%), Positives = 49/94 (52%)
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
F AP+FLT VV G A L+C + G+P P+V W K++ + +F + +
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLY 65
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L I + D+G Y CRA N +GEA A L+V
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 60.1 bits (144), Expect = 1e-08
Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 13/251 (5%)
Query: 268 VDRGNKIKLMVEIS-DPDLTLKWFKNGQEIKPSSKYV-FENVGKKRILTINKCTLADDAA 325
V G +L ++ +P W K+GQ + ++V +E+ + +L I C +D
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGL 308
Query: 326 YEVAVKDEKCFTE----LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKD 381
Y + T + V+EP V L+D +V + EV + + W K+
Sbjct: 309 YTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKE 368
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVIT-NGGQCEAELIVEEKQLE 440
L A+Y +++G L +V +D Y T G + AEL V+ L
Sbjct: 369 ETRLWAS----AKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLR 424
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
L V+ + A+F E++ W +N EV R+ IS G H L I
Sbjct: 425 KLP--RKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQC 482
Query: 501 RPEDEGDYTFV 511
ED G F+
Sbjct: 483 CLEDVGQVAFM 493
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTL 1105
AP FLT L ++ V GY + +C V G P P V W K+ + ED ++I + QG L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
I P D G Y C A N +G + + +L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 55.5 bits (132), Expect = 3e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 1045 RMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF--LITNYQGV 1102
++ P+F+ + V G A C + G P P++ W K+ + KF L G+
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
L L IR S D G Y C VN LG A A +L ++ P
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Score = 54.3 bits (129), Expect = 6e-07
Identities = 52/245 (21%), Positives = 87/245 (35%), Gaps = 6/245 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G L +S +KW ++P KY G L + D Y
Sbjct: 3195 EVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
+ D+ L V P + L +++ G + E+S + A V W K G E
Sbjct: 3255 SCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELS-KAAPVEWRK-GSETL 3312
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
R+ RY ++DG L + D Y + + A L + + +
Sbjct: 3313 RDGD---RYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLR 3369
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
A +CE+S + +W K +R R ++ G +L I + D G
Sbjct: 3370 HQESIEGATATLRCELS-KAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAG 3428
Query: 507 DYTFV 511
+Y+ V
Sbjct: 3429 EYSCV 3433
Score = 53.1 bits (126), Expect = 1e-06
Identities = 81/367 (22%), Positives = 136/367 (37%), Gaps = 65/367 (17%)
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEM-AVEVSEEGAQVMWMKDGVELTREDSFKARYRF 397
L + + +T L++Q+V G V V + V W KDG L +D Y
Sbjct: 5119 LLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD----HYMI 5174
Query: 398 KKDGKR-HILIFSDVVQEDRGRYQVITNGGQ----CEAELIVE----------------- 435
+D + H LI + VV D G Y+ + +AEL V+
Sbjct: 5175 NEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSS 5234
Query: 436 ---------------------EKQL-EVLQDIADLTVKASEQ-AVFKCEVSDEKVTGK-W 471
E QL +V++++ DL V + A F+ +V W
Sbjct: 5235 YFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYW 5294
Query: 472 YKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY-TFVPDGYALSLSAKLNFLEIKV 530
+K+G + S I ++ H L I V ED G Y ++ + + S+ L ++
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSAR--LLVRG 5352
Query: 531 EYVPKQEPPK-IHLDCSGKTSENAIV---VVAGNKLRLDVSITGEPPPVATWLKGDE--- 583
P+++P +H V G+ + V + G P P WL+ +
Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERG 5412
Query: 584 ---VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPD 640
+ T G T + S V+ R+ +G YT +N G+ + S L V +P
Sbjct: 5413 VLWIGPDTPGYT-VASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPK 5471
Query: 641 PPEAVRI 647
E ++
Sbjct: 5472 VEEQEKV 5478
Score = 52.4 bits (124), Expect = 2e-06
Identities = 53/197 (26%), Positives = 81/197 (41%), Gaps = 19/197 (9%)
Query: 443 QDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNG--VEVRPSKRITISHVGRFHKLVIDD 499
+++AD T + E C V+ K WYK+G V+V P I I L++D
Sbjct: 6018 EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPH-HILIEDPDGSCALILDS 6076
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
+ D G Y +A S + + L + VP + K+ A V G
Sbjct: 6077 LTGVDSGQYMC----FAASAAGNCSTLGKILVQVPPRFVNKVR----------ASPFVEG 6122
Query: 560 NKLRLDVSITGEPPPVATWLKGDEVFTT-TEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+ +I G P P W K + TT + +T E R VI +A +ED G Y
Sbjct: 6123 EDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYEC 6182
Query: 619 KVTNPVGEDVASIFLQV 635
++ N +G AS L++
Sbjct: 6183 ELVNRLGSARASAELRI 6199
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/93 (36%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED--PKFLITNYQGVLT 1104
AP FL V G A C V G P+P V W K+ + E P+ +
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L IR P D GTY RA N LG A A L V
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 49.7 bits (117), Expect = 2e-05
Identities = 44/188 (23%), Positives = 74/188 (39%), Gaps = 9/188 (4%)
Query: 450 VKASEQAVFKCE-VSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
V + A C+ V + W K+ V R ++ G ++L I D+ D G Y
Sbjct: 21 VSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQY 80
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
A + L++ E ++ P L +I V G++ +
Sbjct: 81 VCRARNAIGEAFAAVG-LQVDAEAACAEQAPHFLL------RPTSIRVREGSEATFRCRV 133
Query: 569 TGEPPPVATWLKGDEVFTTTEG-RTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGED 627
G P P +W K +G R R+E+ + S+ I +A+ D G Y ++ NP+G
Sbjct: 134 GGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAA 193
Query: 628 VASIFLQV 635
A+ L V
Sbjct: 194 SAAAALVV 201
Score = 47.8 bits (112), Expect = 6e-05
Identities = 60/255 (23%), Positives = 89/255 (34%), Gaps = 21/255 (8%)
Query: 868 PRPQVVWTKGGAPL--DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATI 925
P + W GA + D S V +R A +GE + + A+
Sbjct: 4460 PVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR----DAVASA 4515
Query: 926 RIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYER 985
R+ V+ PP + V + W AP DG + GY V+ + T +W +E
Sbjct: 4516 RLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHEL 4575
Query: 986 NRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFR 1045
C V L G Y FRV G + P T R+ + P
Sbjct: 4576 VPGPECVVDGLAPGETYRFRVAAVGPVGAGE-PVHLPQTVRLAEPPKPVPPQP------- 4627
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
AP+ R V AG +L V +V+W K I+ +F + + L
Sbjct: 4628 SAPE------SRQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPGGRFEVVSQGRQQML 4680
Query: 1106 NIRRPSPFDAGTYTC 1120
I+ + D G Y C
Sbjct: 4681 VIKGFTAEDQGEYHC 4695
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 1059 VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLI-TNYQGVLTLNIRRPSPFDAGT 1117
V G A L+C V G PKP+ VW K+ + E + ++ + Q L I D G
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGL 308
Query: 1118 YTCRAVNELGEALAECKLEVRVP 1140
YTC A N +G+ + + VR P
Sbjct: 309 YTCTASNLVGQTYSSVLVVVREP 331
Score = 47.4 bits (111), Expect = 8e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP-KFLITNYQGVLTLN 1106
P F L D G + L C V G PKP + W K+ ++ DP LI + G L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
+ + D+G Y C A + G K+ V+VP
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107
Score = 44.3 bits (103), Expect = 7e-04
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 16/136 (11%)
Query: 1014 LSDSPGVSKNTARILKTGITFKPFEYKE------HDFRMAPKFLTPLIDRVVVAGYSAAL 1067
+S++ G + ++AR+L G P E +E H+ + P+ L + V G S
Sbjct: 5335 ISNAMGAAYSSARLLVRG----PDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITF 5390
Query: 1068 NCAVRGHPKPKVVWMKNKMEI------REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
+ V G P P V W++ + E + P + + + +L + GTYTC
Sbjct: 5391 SVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCI 5450
Query: 1122 AVNELGEALAECKLEV 1137
A N G+AL L V
Sbjct: 5451 ASNAAGQALCSASLHV 5466
Score = 42.4 bits (98), Expect = 0.003
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Query: 549 TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
T A VV G L I G P P +W K D+ R R+ + D I
Sbjct: 14 TRPKAFVVSVGKDATLSCQIVGNPTPQVSWEK-DQQPVAAGARFRLAQDGDLYRLTILDL 72
Query: 609 QREDEGRYTIKVTNPVGEDVASIFLQV 635
D G+Y + N +GE A++ LQV
Sbjct: 73 ALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 40.4 bits (93), Expect = 0.010
Identities = 63/268 (23%), Positives = 103/268 (38%), Gaps = 37/268 (13%)
Query: 873 VWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
+WT GG + +SR + VR+AA SD+GE SV+ K + +R R
Sbjct: 2769 MWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAA 2828
Query: 932 KAGPPINVMVKEVW-GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTS 990
P +++ W VE + + + +KA +K+ ++ V E
Sbjct: 2829 IIKP-----LEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEG----- 2878
Query: 991 CTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF 1050
T++ L++ + E C + SK+TA + H A F
Sbjct: 2879 -TMAMLVIRGAS-LKDAGEYTCEVE----ASKSTASL--------------HVEEKANCF 2918
Query: 1051 LTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110
L + V +A C HP V W K +E+R K + L L I
Sbjct: 2919 TEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISAL 2977
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEVR 1138
D+ TYTC ++G+A + +L V+
Sbjct: 2978 EKADSDTYTC----DIGQAQSRAQLLVQ 3001
Score = 40.0 bits (92), Expect = 0.013
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAA-LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P+ + L D V G A V+G+P P++ W K+ + +T+ + + TL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
I + D+G Y N +G A + +L VR P
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGP 5353
Score = 39.3 bits (90), Expect = 0.022
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
FL L D + AL C V P+ VVW K+ +++ K+ + G L +
Sbjct: 2649 FLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHD 2707
Query: 1110 PSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
SP DAG YTC +E E + VRV
Sbjct: 2708 VSPEDAGLYTCHVGSE------ETRARVRV 2731
Score = 38.9 bits (89), Expect = 0.028
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 556 VVAGNKL-RLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 614
V G +L + + + G P P W K + T + +K++ + I S RED G
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKI-LHTLEIISVTREDSG 5329
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGE 652
+Y ++N +G +S L +V PD PE + V E
Sbjct: 5330 QYAAYISNAMGAAYSSARL-LVRGPDEPEEKPASDVHE 5366
Score = 38.1 bits (87), Expect = 0.048
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 353 EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVV 412
E +QV G+ V + +EV E +V+W K G+E + R+ G++ +L+
Sbjct: 4631 ESRQVAAGEDVSLELEVVAEAGEVIWHK-GMERIQPGG---RFEVVSQGRQQMLVIKGFT 4686
Query: 413 QEDRGRYQV-ITNGGQCEA 430
ED+G Y + G C A
Sbjct: 4687 AEDQGEYHCGLAQGSICPA 4705
Score = 35.8 bits (81), Expect = 0.24
Identities = 36/125 (28%), Positives = 49/125 (39%), Gaps = 19/125 (15%)
Query: 809 FRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP 868
F VG+ + + A A +R P IR+ T+ +VG G P
Sbjct: 92 FAAVGLQVDAEAACAEQAPHFLLR----PTSIRVREGSEATFRCRVG----------GSP 137
Query: 869 RPQVVWTKGGAPL---DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATI 925
RP V W+K G L D RV V + +R A D G YE V+ EN A+
Sbjct: 138 RPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYE--VRAENPLGAASA 195
Query: 926 RIRVV 930
+V
Sbjct: 196 AAALV 200
Score = 35.4 bits (80), Expect = 0.31
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 2/103 (1%)
Query: 1028 LKTGITFKPFEY-KEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
+K FK ++ KE + P F D G + L C V + W+K+ +
Sbjct: 4877 VKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGV 4936
Query: 1087 EIREDPKFLITNY-QGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
E+ + I G +L I DAG YTC+ N+ G+
Sbjct: 4937 ELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 35.4 bits (80), Expect = 0.31
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDT---VFFVRQAARSDSGEYE 911
GE +G P PQ+ W K GA L T S+ + V +R A++ D G YE
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Query: 912 LSV--QIENMKDTATIRIR 928
+ ++ + + +A +RI+
Sbjct: 6182 CELVNRLGSARASAELRIQ 6200
Score = 35.0 bits (79), Expect = 0.41
Identities = 46/209 (22%), Positives = 85/209 (40%), Gaps = 24/209 (11%)
Query: 271 GNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVF-ENVGKKRILTINKCTLADDAAYE- 327
G +KL ++ P + W+K+G+ ++ ++ E+ L ++ T D Y
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 328 -VAVKDEKCFT--ELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGA---QVMWMKD 381
A C T ++ V+ PP V + G+ + + EGA Q+ W KD
Sbjct: 6088 FAASAAGNCSTLGKILVQVPP-RFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKD 6144
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV-ITN---GGQCEAELIVEEK 437
G LT + F+ + +L+ +ED G Y+ + N + AEL ++
Sbjct: 6145 GALLTTGNKFQTLSEPRSG--LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEK 466
L+ + EQ V EV++++
Sbjct: 6203 MLQAQEQC------HREQLVAAVEVTEQE 6225
Score = 34.7 bits (78), Expect = 0.53
Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 1064 SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
S L+C R PK V W K+ + KF ++ + L I R P DAG Y C+A
Sbjct: 2485 SVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA 2542
Score = 34.7 bits (78), Expect = 0.53
Identities = 79/384 (20%), Positives = 135/384 (35%), Gaps = 62/384 (16%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
QV G + L +E+ + W K + I+P ++ + G++++L I T D Y
Sbjct: 4634 QVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEG-AQVMWMKDGVEL 385
+ + L V + + E ++EG ++W
Sbjct: 4694 HCGLAQGS------ICPAAATFQVALSPASVDEAPQPSLPPEAAQEGDLHLLW------- 4740
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+A R ++ + L + E+ GR Q + EAE + + L
Sbjct: 4741 ------EALARKRRMSREPTLDSISELPEEDGRSQRLPQ----EAEEVAPD--LSEGYST 4788
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGK------WYKNGVEVRPSKRITISHVGR-------- 491
AD + + + DE G K G RP S VG
Sbjct: 4789 ADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAG---RPGTSPLASKVGAPAAPSVKP 4845
Query: 492 --------FHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHL 543
+ + D+ +D GD + D A+ + A +++ E ++ P H
Sbjct: 4846 QQQQEPLAAVRPPLGDLSTKDLGDPSM--DKAAVKIQAAFKGYKVRKEMKQQEGPMFSHT 4903
Query: 544 DCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCS-S 602
G T G+ LRL+ + + A WLK D V T I++ D + S
Sbjct: 4904 --FGDTEAQV-----GDALRLECVVASKADVRARWLK-DGVELTDGRHHHIDQLGDGTCS 4955
Query: 603 FVIESAQREDEGRYTIKVTNPVGE 626
+I R D G YT +V+N G+
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 34.3 bits (77), Expect = 0.69
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+F L D V+ G +A L C + P V W +R K+ + +L L +R
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVR 3244
Query: 1109 RPSPFDAGTYTC 1120
P D+G Y+C
Sbjct: 3245 NLRPQDSGRYSC 3256
Score = 34.3 bits (77), Expect = 0.69
Identities = 91/396 (22%), Positives = 151/396 (38%), Gaps = 51/396 (12%)
Query: 322 DDAAYEV--AVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEM-AVEVSEEGAQVMW 378
D AA ++ A K K E+ +E P+ T D + VGD + + V S+ + W
Sbjct: 4873 DKAAVKIQAAFKGYKVRKEMKQQEGPMFSHT-FGDTEAQVGDALRLECVVASKADVRARW 4931
Query: 379 MKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY--QVITNGGQC--EAELIV 434
+KDGVELT D DG +LI + + + D G Y QV GQ A ++V
Sbjct: 4932 LKDGVELT--DGRHHHIDQLGDGTCSLLI-TGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988
Query: 435 EEKQLEVLQ----DIADLTVKASEQA--VFK----CEVSDEKVTGKWYKNGVEVR-PSKR 483
+ E ++ D +A+ + +F+ EVSDE++ + E P+
Sbjct: 4989 SGSESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW 5048
Query: 484 ITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEI---KVEYVPKQEPPK 540
T F + + + + F L + ++ +E +VE +E P
Sbjct: 5049 QTYREDEHFICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPA 5108
Query: 541 IHLDC----SGKTSENAIVVVA---------GNKLRLDVSITGEPPPVATWLKGDEVFTT 587
+ S TS+ A V + G + D +TG+P P W K ++
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 5168
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ E + +I + D G Y N +G L+ V +
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELR----------VDL 5218
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQ 683
TS D A E Y + GYL R+++G++
Sbjct: 5219 TSTDYDTAADATESSSYFSAQ---GYLSSREQEGTE 5251
Score = 33.9 bits (76), Expect = 0.91
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 935 PPINVMVKEVWGTNALVEWQ-APKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSC 991
PP++ +VK ++ ++ W P + I GY V+K T W +E
Sbjct: 515 PPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPEL 574
Query: 992 TVSDLIVGNEYYFRVYTENICGLS 1015
TV+D+ + FRV N G S
Sbjct: 575 TVADVAEEGNFQFRVSALNSFGQS 598
Score = 33.9 bits (76), Expect = 0.91
Identities = 24/105 (22%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
+P PP + + T+E G ++L +TG P PV +W K +
Sbjct: 6008 LPVWRPPDFEEELADCTAE------LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHI 6061
Query: 593 RIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG--EDVASIFLQV 635
IE + +++S D G+Y + G + I +QV
Sbjct: 6062 LIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Query: 1061 AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTC 1120
AG SA L+C V + +V W K+ ++ K I + L +++ DAG YTC
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 1121 RA 1122
A
Sbjct: 1331 EA 1332
Score = 33.5 bits (75), Expect = 1.2
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+FL L + V G +A L C + V W K +++ K+ + L +R
Sbjct: 3980 RFLRELQHQEVDEGGTAHLCCEL-SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVR 4038
Query: 1109 RPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
DAG YTC + G + L VRVP+
Sbjct: 4039 GVEQEDAGDYTC----DTGHTQSMASLSVRVPR 4067
Score = 33.1 bits (74), Expect = 1.5
Identities = 58/298 (19%), Positives = 111/298 (37%), Gaps = 39/298 (13%)
Query: 833 EIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTS 891
+++EP + L ++ + + + + +V W K G L +S +V +
Sbjct: 1342 DVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAV 1401
Query: 892 DFDTVFFVRQAARSDSGEYELSVQIENMKDTATI-RIRVVEKAGPPINVMVKEVWGTNAL 950
V+QA ++D+GEY + + + + +VV P++ V+ G +
Sbjct: 1402 GCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTT 1461
Query: 951 VEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI------VGNEYYF 1004
+ + + +E+M Y K KK F+ R CT ++ V EY
Sbjct: 1462 LSCEVAQ--AQTEVMWY---KDGKKLS--FSSKVRMEAVGCTRRLVVQQAGQAVAGEYSC 1514
Query: 1005 RVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYS 1064
++ LS V++ A K + + + AG S
Sbjct: 1515 EAGSQR---LSFHLHVAEPKAVFAKEQPASREVQAE--------------------AGTS 1551
Query: 1065 AALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
A L+C V + +V W K+ ++ K + L ++ DAG Y+C+A
Sbjct: 1552 ATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Score = 33.1 bits (74), Expect = 1.5
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 865 QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVR--QAARSDSGEY 910
+G P P++ W K G PL T+ H+R +D + + R DSG+Y
Sbjct: 5285 KGYPAPRLYWFKDGQPL-TASAHIRMTDKKILHTLEIISVTREDSGQY 5331
Score = 32.3 bits (72), Expect = 2.6
Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
F PL D V L C + P V W+K+ +E+R I +L I R
Sbjct: 2168 FSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYR 2226
Query: 1110 PSPFDAGTYTCRA 1122
D G Y C A
Sbjct: 2227 CEFADQGVYVCDA 2239
Score = 31.6 bits (70), Expect = 4.5
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 1061 AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTC 1120
AG SA L+C V + +V W K+ ++ K + L +++ DAG Y+C
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSC 1698
Query: 1121 RA 1122
A
Sbjct: 1699 EA 1700
Score = 30.8 bits (68), Expect = 7.7
Identities = 33/122 (27%), Positives = 48/122 (39%), Gaps = 4/122 (3%)
Query: 818 GRSEPATLAQPVTIREI--AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
G S A LA RE AE P +T G+ L G+P+P+ VW
Sbjct: 213 GTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWK 272
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVR--QAARSDSGEYELSVQIENMKDTATIRIRVVEKA 933
K G + R HV D F ++ +SD G Y + + +++ + V E A
Sbjct: 273 KDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPA 332
Query: 934 GP 935
P
Sbjct: 333 VP 334
Score = 30.8 bits (68), Expect = 7.7
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 1061 AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTC 1120
AG SA L+C V + +V W K+ ++ K + L +++ DAG Y+C
Sbjct: 904 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 1121 RA 1122
A
Sbjct: 963 EA 964
Score = 30.8 bits (68), Expect = 7.7
Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 871 QVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEY 910
+V+W K G L +S +VHV V+QA ++D+G+Y
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 125 bits (314), Expect = 2e-28
Identities = 149/593 (25%), Positives = 226/593 (38%), Gaps = 99/593 (16%)
Query: 269 DRGNKIKLMVEISDPD--LTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G+ +L ++SD + ++W K G E+ KY + G R L I++ D Y
Sbjct: 4080 ETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVEL 385
+K L V EP V IV L D +V + VE + EVS GA V W G+ L
Sbjct: 4140 ACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPL 4199
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+ + R DG+ H L V ED G A+L V ++ +L+ +
Sbjct: 4200 QSNEVTEVAVR---DGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPL 4256
Query: 446 ADLTVKASEQAVFKCEVSDEK-VTGKWYKNGVEVRPSKRITIS-HVGRFHKLVIDDVRPE 503
D+ + + A F+C +S +W GV ++ ++ I+ G H L + V E
Sbjct: 4257 QDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316
Query: 504 DEGDYTF----VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK----------- 548
D G +F L ++AK N + +E V E + +C
Sbjct: 4317 DAGTVSFHVGTCSSEAQLKVTAK-NTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLL 4375
Query: 549 ------TSENAIVVVAGNKLRLDVSITGEPPPVA---TWLKGDEV---FTTTEG------ 590
TSENA VV N LR + + P + T+L GD V F T G
Sbjct: 4376 DDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEIL 4435
Query: 591 --------RTRIEKRVDC-----------SSFVIESAQREDEGRYTI------------- 618
R + C S ++ +A + D+ +T+
Sbjct: 4436 EPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRS 4495
Query: 619 -------KVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
+VT + VAS L V+ +PDPPE + + L W PM DGG +
Sbjct: 4496 AQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLC 4555
Query: 672 GYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP------- 724
GY VE K+ + +W +L E+ + G Y RV AV +G +P
Sbjct: 4556 GYRVEVKEGATGQW-RLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTV 4614
Query: 725 ----SMNTKPFMPIAPTS------EPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P AP S E + L +E V + + + RI GG
Sbjct: 4615 RLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGG 4667
Score = 105 bits (263), Expect = 2e-22
Identities = 71/283 (25%), Positives = 126/283 (44%), Gaps = 12/283 (4%)
Query: 269 DRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV 328
+ G + +S D+ + WF++G ++PS K+ G LTI+ L D V
Sbjct: 1911 EEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 329 AVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTRE 388
+ L V+E PVL LE Q V V + VE++ ++ W ++ L
Sbjct: 1971 EAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPG 2030
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADL 448
+ + +G RH L+ +V DRG + T + +A+L VE +Q+ +++ + +
Sbjct: 2031 KNVEIH----AEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAV 2086
Query: 449 TVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
+ A + ++S V G W ++G+ + ++ G H L + +RPED G
Sbjct: 2087 EAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLM 2146
Query: 509 TFVPDGYALSLSAKLNFLEIKVEY------VPKQEPPKIHLDC 545
F +G + SA+L E+ V + V E K+ L+C
Sbjct: 2147 VFKAEG--VHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLEC 2187
Score = 101 bits (251), Expect = 5e-21
Identities = 74/271 (27%), Positives = 119/271 (43%), Gaps = 8/271 (2%)
Query: 242 LKRLKKAKVEVK-KSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSS 300
LK A++EV+ K F K LD +RG + L E+SDP+ + W K+G ++ PS
Sbjct: 2632 LKVSTSARLEVRVKPVVFLKALDDLSAEERGT-LALQCEVSDPEAHVVWRKDGVQLGPSD 2690
Query: 301 KYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVG 360
KY F + R L ++ + D Y V E+ + V + V I L+ +V G
Sbjct: 2691 KYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEG 2750
Query: 361 DRVEMAVEVSEEGAQ--VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGR 418
+ +S E A MW G + F+A + G+++IL+ + D G
Sbjct: 2751 ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQA----TRQGRKYILVVREAAPSDAGE 2806
Query: 419 YQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEV 478
G +A LIV E+ +++ + D V E +CE+S W K+ +
Sbjct: 2807 VVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAI 2866
Query: 479 RPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
R S++ + G LVI +D G+YT
Sbjct: 2867 RKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897
Score = 99.8 bits (247), Expect = 1e-20
Identities = 77/316 (24%), Positives = 135/316 (42%), Gaps = 26/316 (8%)
Query: 227 EKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT 286
++++F IT+ +G+ + + EV Q + G L E++ P
Sbjct: 1151 QRVSFHLHITEPKGVFAKEQSVHNEV--------------QAEAGTTAMLSCEVAQPQTE 1196
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
+ W+K+G+++ SSK E G R L + + AD Y ++ +L + EP
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKA 1256
Query: 347 LIVTPL---EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
+ + + G ++ EV++ +V W KDG +L S ++ R + G
Sbjct: 1257 VFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKL----SSSSKVRIEAAGCM 1312
Query: 404 HILIFSDVVQEDRGRYQVITNGGQCEAELIVEE-KQLEVLQDIADLTVKASEQAV--FKC 460
L+ Q D G Y G + L V E K + + +A V+A A+ C
Sbjct: 1313 RQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSC 1372
Query: 461 EVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
EV+ + WYK+G ++ S ++ + VG +LV+ D G+Y+ G LS S
Sbjct: 1373 EVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFS 1432
Query: 521 AKLNFLEIKVEYVPKQ 536
L+ E KV + +Q
Sbjct: 1433 --LDVAEPKVVFAKEQ 1446
Score = 98.2 bits (243), Expect = 4e-20
Identities = 125/585 (21%), Positives = 212/585 (36%), Gaps = 64/585 (10%)
Query: 49 EPTGVFLKKP---DSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFS 105
EP VF K+ + E G A + +V + + W+K G + S
Sbjct: 885 EPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTE----VTWYK---------DGKKLS 931
Query: 106 FKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSL 165
+ T L + + D G Y E + F++DV+ P+
Sbjct: 932 SSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFHLDVKEPKV------- 980
Query: 166 ESFKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSE 225
F + S+ E S L + + KD L ++ KG ++
Sbjct: 981 -VFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRR-- 1037
Query: 226 YEKIAFQYGITDL-------RGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMV 278
+ Q G TD RG + E K A + + Q + G L
Sbjct: 1038 -RLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSC 1096
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E++ + W+K+G+++ SSK E G R L + + AD Y ++
Sbjct: 1097 EVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFH 1156
Query: 339 LFVKEPPVLIVTPLE---DQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARY 395
L + EP + + Q G ++ EV++ +V W KDG +L S ++
Sbjct: 1157 LHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKL----SSSSKV 1212
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAEL-IVEEKQLEVLQDIA--DLTVKA 452
R + G L+ V + D G Y G + +L I E K + + + ++ +A
Sbjct: 1213 RMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEA 1272
Query: 453 SEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVP 512
A CEV+ + WYK+G ++ S ++ I G +LV+ D G+YT
Sbjct: 1273 GASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 513 DGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEP 572
G LS L+ E K + +Q + + AG L +
Sbjct: 1333 GGQRLSF--HLDVSEPKAVFAKEQ------------LAHRKVQAEAGAIATLSCEVAQAQ 1378
Query: 573 PPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
V TW K D ++ + R+E V++ A + D G Y+
Sbjct: 1379 TEV-TWYK-DGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYS 1421
Score = 97.8 bits (242), Expect = 5e-20
Identities = 82/360 (22%), Positives = 140/360 (38%), Gaps = 25/360 (6%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
Q G L E++ + W+K+G+++ SSK E VG R L + + A Y
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEY 1512
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPL---EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGV 383
++ L V EP + + Q G ++ EV++ +V W KDG
Sbjct: 1513 SCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGK 1572
Query: 384 ELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQ 443
+L S ++ R + G L+ + Q D G Y + L V E ++ +
Sbjct: 1573 KL----SSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAK 1628
Query: 444 DIA---DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
+ ++ +A A CEV+ + WYK+G ++ S ++ + VG +LV+
Sbjct: 1629 EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQA 1688
Query: 501 RPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
D G+Y+ G LS + LE ++ P + P +VV
Sbjct: 1689 GQADAGEYSCEAGGQRLSFRLHVAELEPQISERPCRREP--------------LVVKEHE 1734
Query: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
+ L ++ TWLK D V R + D + + AQ D Y+ +V
Sbjct: 1735 DIILTATLATPSAATVTWLK-DGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRV 1793
Score = 97.8 bits (242), Expect = 5e-20
Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 4/223 (1%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
++W+K+ + PS K+ G+ L I + AD Y TE+ V+ V
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREV 2558
Query: 347 LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
+ PL+D + + E+S E +V W +G+ L DSF + G+RH L
Sbjct: 2559 TVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYN-DSF---HEISHKGRRHTL 2614
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
+ + + D G + + A L V K + L+ + DL+ + +CEVSD +
Sbjct: 2615 VLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPE 2674
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
W K+GV++ PS + H LV+ DV PED G YT
Sbjct: 2675 AHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYT 2717
Score = 96.7 bits (239), Expect = 1e-19
Identities = 74/270 (27%), Positives = 114/270 (42%), Gaps = 20/270 (7%)
Query: 240 GMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPS 299
G+ KRLK +V +S +F L SDP + W G+ + S
Sbjct: 2737 GITKRLKTMEVLEGESCSFECVLSHE-------------SASDPAM---WTVGGKTVGSS 2780
Query: 300 SKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFV 359
S++ G+K IL + + +D +V+ L V+E P I+ PLEDQ V
Sbjct: 2781 SRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAP 2840
Query: 360 GDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY 419
G+ VE+ E+S G V W+KD + + +Y +G +L+ +D G Y
Sbjct: 2841 GEDVELRCELSRAGTPVHWLKDRKAIRKSQ----KYDVVCEGTMAMLVIRGASLKDAGEY 2896
Query: 420 QVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVR 479
+ A L VEEK +++ +L V+ AVF C+ T W K +E+R
Sbjct: 2897 TCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELR 2956
Query: 480 PSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
S + S G +L I + D YT
Sbjct: 2957 ASGKHQPSQEGLTLRLTISALEKADSDTYT 2986
Score = 92.8 bits (229), Expect = 2e-18
Identities = 82/379 (21%), Positives = 148/379 (39%), Gaps = 29/379 (7%)
Query: 249 KVEVKKSAAFTKKLDPAYQVDR-----GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYV 303
++EV+ + T PA + +L+ E+SD + W K+G+ + P KY
Sbjct: 694 RMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYE 753
Query: 304 FENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQV--FVGD 361
+ +R+L + D YE + + +L V+ + + V G
Sbjct: 754 VQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAVAGG 813
Query: 362 RVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
+ E SE V W KDG+EL R+ + G RH L+ + V ++D G Y
Sbjct: 814 PAQFECETSEAHVHVHWYKDGMELGHSGE---RFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 422 ITNGGQCEAELIVEEKQLEVLQD---IADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEV 478
+ L V E ++ ++ L +A A CEV+ + WYK+G ++
Sbjct: 871 RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKL 930
Query: 479 RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEP 538
S ++ + G +LV+ D G+Y+ G LS L+ E KV + Q
Sbjct: 931 SSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSF--HLDVKEPKVVFAKDQ-- 986
Query: 539 PKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRV 598
+ + + AG L + V + G ++ ++ + +E +
Sbjct: 987 ----------VAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSL--KVHVEAKG 1034
Query: 599 DCSSFVIESAQREDEGRYT 617
V++ A + D G Y+
Sbjct: 1035 CRRRLVVQQAGKTDAGDYS 1053
Score = 92.4 bits (228), Expect = 2e-18
Identities = 91/417 (21%), Positives = 162/417 (38%), Gaps = 44/417 (10%)
Query: 227 EKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT 286
++++FQ IT+ + + + + EV+ A G L E++
Sbjct: 1243 QRVSFQLHITEPKAVFAKEQLVHNEVRTEA--------------GASATLSCEVAQAQTE 1288
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
+ W+K+G+++ SSK E G R L + + AD Y ++ L V EP
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKA 1348
Query: 347 LIVTPL---EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
+ Q G ++ EV++ +V W KDG +L S ++ R + G
Sbjct: 1349 VFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKL----SSSSKVRMEAVGCT 1404
Query: 404 HILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA---DLTVKASEQAVFKC 460
L+ Q D G Y G + L V E ++ ++ ++ +A C
Sbjct: 1405 RRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSC 1464
Query: 461 EVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLS 520
EV+ + WYK+G ++ S ++ + VG +LV+ G+Y+ + + LS
Sbjct: 1465 EVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSC--EAGSQRLS 1522
Query: 521 AKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK 580
L+ E K + K++P + TS VA + TW K
Sbjct: 1523 FHLHVAEPKAVFA-KEQPASREVQAEAGTSATLSCEVA------------QAQTEVTWYK 1569
Query: 581 GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVD 637
D ++ + R+E V++ A + D G Y+ K G+ S L V +
Sbjct: 1570 -DGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCK----AGDQRLSFHLHVAE 1621
Score = 90.5 bits (223), Expect = 8e-18
Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 7/257 (2%)
Query: 286 TLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPP 345
T+ W K+G EI+ S ++ + G LT++ + D A Y V E + V+E
Sbjct: 1749 TVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVA 1808
Query: 346 VLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHI 405
LE +G V +A E+S A+V+W +L R++ +G
Sbjct: 1809 AKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLR----VGKRFQMVAEGPVRS 1864
Query: 406 LIFSDVVQEDRGRYQVITNGGQCEAELIVE-EKQLEVLQDIADLTVKASEQAVFKCEVSD 464
L + ED G Y + A+L V + ++ + ++ + + +A F+C VS
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP 1924
Query: 465 EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLN 524
V W+++G ++PS++ IS G H L I D+ ED G T +G S SA L
Sbjct: 1925 SDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG--ASSSAALR 1982
Query: 525 FLEIKVEYVPKQEPPKI 541
E V + K EP +
Sbjct: 1983 VREAPVLFKKKLEPQTV 1999
Score = 90.5 bits (223), Expect = 8e-18
Identities = 83/345 (24%), Positives = 136/345 (39%), Gaps = 27/345 (7%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E+S D ++W NG + S + + G++ L + AD +
Sbjct: 2580 ELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSAR 2639
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
L V+ PV+ + L+D + + EVS+ A V+W KDGV+L D +Y F
Sbjct: 2640 LEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSD----KYDFL 2695
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
L+ DV ED G Y + A + V + + + + + + V E F
Sbjct: 2696 HTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSF 2755
Query: 459 KCEVSDEKVT--GKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYA 516
+C +S E + W G V S R + GR + LV+ + P D G+ F G
Sbjct: 2756 ECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRG-- 2813
Query: 517 LSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN-KLRLDVSITGEPPPV 575
L K + ++ P I K E+ V + +LR ++S G P
Sbjct: 2814 ---------LTSKASLIVRERPAAII-----KPLEDQWVAPGEDVELRCELSRAGTP--- 2856
Query: 576 ATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
WLK + ++ + + + VI A +D G YT +V
Sbjct: 2857 VHWLKDRKAIRKSQ-KYDVVCEGTMAMLVIRGASLKDAGEYTCEV 2900
Score = 90.1 bits (222), Expect = 1e-17
Identities = 66/266 (24%), Positives = 111/266 (41%), Gaps = 6/266 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
Q + G+ L E+S+P T+ W K G +++ + + G L + D Y
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
+ L V PV + L+ Q+V G + E+S GA V W K ++L
Sbjct: 3960 TCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLF 4019
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
A+Y+ +DG L+ V QED G Y T Q A L V + + +
Sbjct: 4020 P----CAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQ 4075
Query: 447 DLTVKASEQAVFKCEVSDEK--VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPED 504
L + + A C++SD + +W K GVE+ + + G +L+I + +D
Sbjct: 4076 SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKD 4135
Query: 505 EGDYTFVPDGYALSLSAKLNFLEIKV 530
G+Y V G + S ++ E+ +
Sbjct: 4136 TGEYACVTGGQKTAASLRVTEPEVTI 4161
Score = 89.7 bits (221), Expect = 1e-17
Identities = 64/251 (25%), Positives = 104/251 (41%), Gaps = 5/251 (1%)
Query: 258 FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINK 317
F KKL+P V+ + + L VE++ P L+W +N + P G + L ++
Sbjct: 1990 FKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHN 2048
Query: 318 CTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM 377
AD + D+K +L V+ V +V L+ + M V++S
Sbjct: 2049 VGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGS 2108
Query: 378 WMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
W +DG+ + + R G H L S + ED G G A L+V E
Sbjct: 2109 WTRDGLRFQQGPTCHLAVR----GPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTEL 2164
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVI 497
+ + + D+ E+ +CE+S V +W K+GVE+R K + I+ G L I
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224
Query: 498 DDVRPEDEGDY 508
D+G Y
Sbjct: 2225 YRCEFADQGVY 2235
Score = 89.0 bits (219), Expect = 2e-17
Identities = 63/263 (23%), Positives = 103/263 (39%), Gaps = 31/263 (11%)
Query: 278 VEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFT 337
V++S D+ W ++G + G LT++ D +
Sbjct: 2098 VQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSA 2157
Query: 338 ELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKAR--- 394
L V E PV PL+D ++V + E+S V W+KDGVEL +
Sbjct: 2158 RLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQG 2217
Query: 395 -------YR---------------------FKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
YR K G+ + LI+ V+ ED G Q +
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENA 2277
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
+ A+L V+E + +++ + D + V +C+VS +W+K E++P + +
Sbjct: 2278 ESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYEL 2337
Query: 487 SHVGRFHKLVIDDVRPEDEGDYT 509
G + KL+I DV EDE YT
Sbjct: 2338 VSDGLYRKLIISDVHAEDEDTYT 2360
Score = 87.8 bits (216), Expect = 5e-17
Identities = 89/365 (24%), Positives = 156/365 (42%), Gaps = 36/365 (9%)
Query: 265 AYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDA 324
A Q G ++ V+++ +WF +GQ +K SS Y + LTI + +
Sbjct: 621 AVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHG 679
Query: 325 A--------YEVAVKDE-KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ 375
A E +++ E + L +PP + + + ++ E+S++ A
Sbjct: 680 AQLKFVANGIESSIRMEVRAAPGLTANKPP---AAAAREVLARLHEEAQLLAELSDQAAA 736
Query: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVE 435
V W+KDG R S +Y + R +L+ DV ++D G Y+ ++ GG+ +L V+
Sbjct: 737 VTWLKDG----RTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQ 792
Query: 436 EKQLEVLQDIADLTVK--ASEQAVFKCEVSDEKVTGKWYKNGVEVRPS-KRITISHVGRF 492
+ +D+A V A A F+CE S+ V WYK+G+E+ S +R VG
Sbjct: 793 GLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTR 852
Query: 493 HKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSEN 552
H+LV V +DEG Y S ++ E V++ + PK+ + + +
Sbjct: 853 HRLVAATVTRQDEGTY-----------SCRVG--EDSVDFRLRVSEPKV-VFAKEQLARR 898
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
+ AG L + V TW K D ++ + +E V++ A + D
Sbjct: 899 KLQAEAGASATLSCEVAQAQTEV-TWYK-DGKKLSSSSKVCMEATGCTRRLVVQQAGQAD 956
Query: 613 EGRYT 617
G Y+
Sbjct: 957 AGEYS 961
Score = 79.0 bits (193), Expect = 2e-14
Identities = 84/388 (21%), Positives = 144/388 (37%), Gaps = 28/388 (7%)
Query: 253 KKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRI 312
+K+ FT++L ++G + + P T+ W K E++ S K+ G
Sbjct: 2913 EKANCFTEELTNLQVEEKGTAV-FTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLR 2971
Query: 313 LTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEE 372
LTI+ AD Y + + +L V+ V I+ LED V G +S
Sbjct: 2972 LTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPA 3031
Query: 373 GAQ-VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAE 431
+ V W D L + + + G H+L + +D G + A
Sbjct: 3032 NYEPVHWFLDKTPLHANELNEID---AQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAA 3088
Query: 432 LIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGR 491
L V EK +++ D T+ E CE S + W K+G +R S R +SH G
Sbjct: 3089 LRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGH 3148
Query: 492 FHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSE 551
+L+I +D G Y G S +++ ++ + K
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD--------------- 3193
Query: 552 NAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
+ V+ G L ++ PV W G+ V + + + + V+ + + +
Sbjct: 3194 --LEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGD-KYSLRQEGAMLELVVRNLRPQ 3249
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVP 639
D GRY+ G+ S L V +P
Sbjct: 3250 DSGRYSCS----FGDQTTSATLTVTALP 3273
Score = 77.8 bits (190), Expect = 5e-14
Identities = 133/578 (23%), Positives = 216/578 (37%), Gaps = 101/578 (17%)
Query: 371 EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVV-----------QEDRGRY 419
E + +W KDG +T +G+RH+ ++ D Q DRG Y
Sbjct: 264 EPKPETVWKKDGQLVT-------------EGRRHV-VYEDAQENFVLKILFCKQSDRGLY 309
Query: 420 QVITNG--GQCEAEL--IVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNG 475
+ GQ + + +V E + + + DL V+ E A F CEV W+K
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEE 369
Query: 476 VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVP 534
+ S + I G +L + +V +D+ Y P+G E+ V+
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG-------SRTVAELAVQGNL 422
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRI 594
++ P+ KT+ V G+ V + PV WL+ E GR I
Sbjct: 423 LRKLPR-------KTA-----VRVGDTAMFCVELAVPVGPVH-WLRNQEE-VVAGGRVAI 468
Query: 595 EKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDW 654
+ I ED G+ + + PP + + E
Sbjct: 469 SAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESS 528
Query: 655 AILVWEPPMYDGGKPVT--GYLVERKKKGSQRWMKLNFEVFTETTYEST--KMIEGILYE 710
IL W PP + G +PVT GYLVE+KK G+ W++ + E T E T + E ++
Sbjct: 529 VILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCH-EAEWVATPELTVADVAEEGNFQ 586
Query: 711 MRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGA--GGI 768
RV A+N+ G S P++ T +HL + T P + A GG
Sbjct: 587 FRVSALNSFGQS-------PYLEFPGT---VHLAPKLAVRT-------PLKAVQAVEGGE 629
Query: 769 DGYLVEYCLEGSEEW------VPANTEPVERCG-----FTVKNLPT---GARILFRVVGV 814
+ V+ + + EW + A++ C T++ +P GA++ F G+
Sbjct: 630 VTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGI 689
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVW 874
+ R E +R + P + + ++ E+ L+ + V W
Sbjct: 690 ESSIRME---------VRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQ-AAAVTW 739
Query: 875 TKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYE 911
K G L + V+ S V VR AR D+G YE
Sbjct: 740 LKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYE 777
Score = 77.8 bits (190), Expect = 5e-14
Identities = 178/900 (19%), Positives = 326/900 (36%), Gaps = 133/900 (14%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+ G+ L E+S ++W K + ++ ++ G + L I + D Y
Sbjct: 3724 EATEGDTATLWCELSKA-APVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEY 3782
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
E+ L V+ P + +++Q+ G + E+S+ A V W K L
Sbjct: 3783 SCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSK-AAPVEWRKGSETLR 3841
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
D RY ++DG R L + D G Y + + A L V Q + +
Sbjct: 3842 GGD----RYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQ 3897
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
L + A +CE+S+ T W K G++++ + R G +LV+ D++ ED G
Sbjct: 3898 SLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTG 3957
Query: 507 DYTFVPDGYALS-----LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNK 561
+YT A S +A + FL ++++ E HL C
Sbjct: 3958 EYTCTCGSQATSATLTVTAAPVRFLR-ELQHQEVDEGGTAHLCC---------------- 4000
Query: 562 LRLDVSITGEPPPVATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
++S G W KG ++F + ++ + + ++ ++ED G YT
Sbjct: 4001 ---ELSRAGAS---VEWRKGSLQLFPC--AKYQMVQDGAAAELLVRGVEQEDAGDYTCDT 4052
Query: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
+ + +AS+ V VP P R+ S+ ++ + + L + +
Sbjct: 4053 GHT--QSMASL---SVRVPRPKFKTRLQSLEQETGDIA----------RLCCQLSDAESG 4097
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAP--TS 738
+W+K E+ YE +G E+ + + A + + T A +
Sbjct: 4098 AVVQWLKEGVELHAGPKYEMRS--QGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVT 4155
Query: 739 EPLHLIVEDVTDTTTTLKWR-----PPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVER 793
EP IV + D T +R GA G V++CL+G TE R
Sbjct: 4156 EPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATG-----VQWCLQGLPLQSNEVTEVAVR 4210
Query: 794 CG----FTVKNL-PTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQ 848
G +K + P A + +G N A ++ A VTI E + ++
Sbjct: 4211 DGRIHTLRLKGVTPEDAGTVSFHLG-NHASSAQLTVRAPEVTILEPLQDVQL-------- 4261
Query: 849 TYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF--VRQAARSD 906
G+ + + W GG PL + ++ T + T+ + + D
Sbjct: 4262 ----SEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLED 4317
Query: 907 SGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966
+G +S + A +++ N +V+ + AL +G +
Sbjct: 4318 AG--TVSFHVGTCSSEAQLKVTAK-------NTVVRGLENVEAL--------EGGEALFE 4360
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENI-----CGLSDSPGVS 1021
+ + + W + + HTS + N + +N+ C ++ G
Sbjct: 4361 CQLSQPEVAAHTWL-LDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDM 4419
Query: 1022 KNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAV-RGHPKPKVV 1080
+A + G +R+ + L PL + V AG A C + P +
Sbjct: 4420 VTSAFLTVRG------------WRL--EILEPLKNAAVRAGAQACFTCTLSEAVPVGEAS 4465
Query: 1081 WMKNKMEIR-EDPKFLITNYQGVLTLNIRRPSPFDAG--TYTCRAVNELGEALAECKLEV 1137
W N ++ +D + +T L +R P AG T+ CR +A+A +L V
Sbjct: 4466 WYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR------DAVASARLTV 4519
Score = 75.1 bits (183), Expect = 4e-13
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 7/259 (2%)
Query: 250 VEVKKSAA-FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVG 308
V+V++ AA F + L+P + G + L E+S + W +++ ++ G
Sbjct: 1802 VQVEEVAAKFCRLLEPVCG-ELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEG 1860
Query: 309 KKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVL-IVTPLEDQQVFVGDRVEMAV 367
R LT+ D Y +D+ +L V P V+ ++ L G
Sbjct: 1861 PVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQC 1920
Query: 368 EVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQ 427
VS V+W +DG L + F + G H L SD+V ED G+ V G
Sbjct: 1921 VVSPSDVAVVWFRDGALLQPSEKF----AISQSGASHSLTISDLVLEDAGQITVEAEGAS 1976
Query: 428 CEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITIS 487
A L V E + + + TV+ + E++ +W +N + P K + I
Sbjct: 1977 SSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIH 2036
Query: 488 HVGRFHKLVIDDVRPEDEG 506
G H+LV+ +V D G
Sbjct: 2037 AEGARHRLVLHNVGFADRG 2055
Score = 70.5 bits (171), Expect = 9e-12
Identities = 79/353 (22%), Positives = 134/353 (37%), Gaps = 29/353 (8%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
++W+K + ++ ++ G + L I D Y E+ L V+ P
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPS 3714
Query: 347 LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
+ L +++ GD + E+S+ A V W K G E R+ R+ ++DG R L
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSK-AAPVEWRK-GHETLRDGD---RHSLRQDGSRCEL 3769
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
+ D G Y + + A L V ++D+ + + AV +CE+S +
Sbjct: 3770 QIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELS-KA 3828
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
+W K +R R ++ G +L I + D G+Y+ V S + L
Sbjct: 3829 APVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSAT-----L 3883
Query: 527 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 586
++ +EP + G T+ L+ ++S EP W KG +
Sbjct: 3884 TVRAPQPVFREPLQSLQAEEGSTAT----------LQCELS---EPTATVVWSKGG-LQL 3929
Query: 587 TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVP 639
GR + + V++ QRED G YT G S L V P
Sbjct: 3930 QANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGSQATSATLTVTAAP 3978
Score = 68.2 bits (165), Expect = 4e-11
Identities = 79/311 (25%), Positives = 116/311 (37%), Gaps = 49/311 (15%)
Query: 375 QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITN---------- 424
QV W KD + AR+R +DG + L D+ D G+Y
Sbjct: 40 QVSWEKDQQPVAAG----ARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95
Query: 425 GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNGVEVRP--S 481
G Q +AE E+ L + V+ +A F+C V + W K+G +
Sbjct: 96 GLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDG 155
Query: 482 KRITISHVGRFHKLVIDDVRPEDEGDY---------------TFVPDGYAL--------S 518
R+ + +G L I RP D G Y V D A S
Sbjct: 156 PRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTS 215
Query: 519 LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW 578
+A L L+ + E + + P T V G RL +TGEP P W
Sbjct: 216 TAALLAHLQRRREAMRAEGAPA----SPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVW 271
Query: 579 LKGDEVFTTTEGRTRIEKRVDCSSFVIE--SAQREDEGRYTIKVTNPVGEDVASIFLQVV 636
K ++ TEGR + +FV++ ++ D G YT +N VG+ +S+ L VV
Sbjct: 272 KKDGQL--VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVV 328
Query: 637 DVPDPPEAVRI 647
P P R+
Sbjct: 329 REPAVPFKKRL 339
Score = 67.0 bits (162), Expect = 1e-10
Identities = 53/234 (22%), Positives = 91/234 (38%), Gaps = 5/234 (2%)
Query: 276 LMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKC 335
L ++S ++WFK QE++P KY + G R L I+ D+ Y D K
Sbjct: 2309 LECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKT 2368
Query: 336 FTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKAR 394
+ FV+E + IV L+D V E S + W+ L
Sbjct: 2369 SAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVL----QAGGN 2424
Query: 395 YRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASE 454
+++G H L+ G + A L+V + + + + + T + +
Sbjct: 2425 VGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQ 2484
Query: 455 QAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
V C+ +WYK+ + PS++ +S G+ +L I + P D G Y
Sbjct: 2485 SVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Score = 64.7 bits (156), Expect = 5e-10
Identities = 81/380 (21%), Positives = 143/380 (37%), Gaps = 31/380 (8%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPV 346
++W K + ++ +Y G K L I +AD Y E+ L V+ P+
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPI 3626
Query: 347 LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406
L +++ G + E+S+ A V W K G E R+ R+ ++DG R L
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKM-APVEWWK-GHETLRDGD---RHSLRQDGARCEL 3681
Query: 407 IFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 466
+V ED G Y + + A L V + ++ + + + A CE+S +
Sbjct: 3682 QIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELS-KA 3740
Query: 467 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFL 526
+W K +R R ++ G +L I + D G+Y+ V S + + L
Sbjct: 3741 APVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRAL 3800
Query: 527 EIK-VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 585
+ +E V QE E A V+ + L + E + L+G + +
Sbjct: 3801 PARFIEDVKNQE-----------AREGATAVL---QCELSKAAPVEWRKGSETLRGGDRY 3846
Query: 586 TTTEGRTRIEKRV------DCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVP 639
+ + TR E ++ D + Q T++ PV + LQ +
Sbjct: 3847 SLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREP----LQSLQAE 3902
Query: 640 DPPEAVRITSVGEDWAILVW 659
+ A + E A +VW
Sbjct: 3903 EGSTATLQCELSEPTATVVW 3922
Score = 63.9 bits (154), Expect = 8e-10
Identities = 144/692 (20%), Positives = 237/692 (34%), Gaps = 82/692 (11%)
Query: 251 EVKKSAAFTKKLDPAYQVDR--------GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKY 302
E + SA+ T + PA+ + R G L E+S ++W K + ++ ++
Sbjct: 3348 EERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELSKA-APVEWRKGRESLRDGDRH 3406
Query: 303 VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDR 362
G L I +AD Y +E+ L VK P L +++ G
Sbjct: 3407 SLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGAT 3466
Query: 363 VEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI 422
+ E+S+ A V W K L D RY +++G R L + D G Y +
Sbjct: 3467 AMLWCELSKV-APVEWRKGPENLRDGD----RYILRQEGTRCELQICGLAMADAGEYLCV 3521
Query: 423 TNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSK 482
+ A L + ++D+ + + AV +CE++ +W K +R
Sbjct: 3522 CGQERTSATLTIRALPARFIEDVKNQEAREGATAVLQCELNSAAPV-EWRKGSETLRDGD 3580
Query: 483 RITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH 542
R ++ G +L I + D G+Y+ V S + L IK + E
Sbjct: 3581 RYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNE----- 3635
Query: 543 LDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSS 602
+ +E A V LR ++S + PV W KG E + + + C
Sbjct: 3636 -----EATEGATAV-----LRCELS---KMAPV-EWWKGHETLRDGDRHSLRQDGARC-E 3680
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDP-PEAVRITSVGEDWAILVWEP 661
I ED G Y G++ S L V +P E +R E +W
Sbjct: 3681 LQIRGLVAEDAGEYLCM----CGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLW-- 3734
Query: 662 PMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGV 721
E K W K E + S + +G E+++ + +
Sbjct: 3735 -------------CELSKAAPVEWRK-GHETLRDGDRHSLRQ-DGSRCELQIRGLAVVDA 3779
Query: 722 SQPSM---NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLE 778
+ S + + + P I EDV + R GA + E
Sbjct: 3780 GEYSCVCGQERTSATLTVRALPARFI-EDVKNQEA--------REGATAV--LQCELSKA 3828
Query: 779 GSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA----QPVTIREI 834
EW R G G R ++ G+++A E + + T+
Sbjct: 3829 APVEW--RKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVR 3886
Query: 835 AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTSDF 893
A P R P Q+ + G L +P VVW+KGG L + R R
Sbjct: 3887 APQPVFREP---LQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGC 3942
Query: 894 DTVFFVRQAARSDSGEYELSVQIENMKDTATI 925
++ R D+GEY + + T T+
Sbjct: 3943 TAELVLQDLQREDTGEYTCTCGSQATSATLTV 3974
Score = 61.2 bits (147), Expect = 5e-09
Identities = 96/440 (21%), Positives = 152/440 (34%), Gaps = 45/440 (10%)
Query: 42 DQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSG 101
D E FL +P S+ V G +A +V G +P + W K LG G
Sbjct: 100 DAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSP---RPAVSWSKDG-RRLGEPDG 155
Query: 102 ARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDAS 161
R +E +++ L I D G Y + + S + V++ D +
Sbjct: 156 PRVRVEELGEASA------LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTA 209
Query: 162 GQSLESF--------KRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPE 213
+ S +R +++ A S + V E + + P
Sbjct: 210 SRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPET 269
Query: 214 IWE-----LLKGAKKSEYE--------KIAF-------QYGITDLRGMLKRLKKAKVEVK 253
+W+ + +G + YE KI F Y T + + V V+
Sbjct: 270 VWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329
Query: 254 KSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRIL 313
+ A KK +V + E+ P WFK + S+KY E G +R L
Sbjct: 330 EPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRL 389
Query: 314 TINKCTLADDAAYEVAVKD-EKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEE 372
T+ + DDA Y + + EL V+ L+ V VGD VE++
Sbjct: 390 TVRNVSADDDAVYICETPEGSRTVAELAVQGN--LLRKLPRKTAVRVGDTAMFCVELAVP 447
Query: 373 GAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAEL 432
V W+++ E+ R +G RH L S ED G+ + Q +
Sbjct: 448 VGPVHWLRNQEEVVA----GGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQF 503
Query: 433 IVEEKQLEVLQDIADLTVKA 452
V + LQ D VKA
Sbjct: 504 CVSAPRKPPLQPPVDPVVKA 523
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/94 (36%), Positives = 49/94 (52%)
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
F AP+FLT VV G A L+C + G+P P+V W K++ + +F + +
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLY 65
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L I + D+G Y CRA N +GEA A L+V
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 60.1 bits (144), Expect = 1e-08
Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 13/251 (5%)
Query: 268 VDRGNKIKLMVEIS-DPDLTLKWFKNGQEIKPSSKYV-FENVGKKRILTINKCTLADDAA 325
V G +L ++ +P W K+GQ + ++V +E+ + +L I C +D
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGL 308
Query: 326 YEVAVKDEKCFTE----LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKD 381
Y + T + V+EP V L+D +V + EV + + W K+
Sbjct: 309 YTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKE 368
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVIT-NGGQCEAELIVEEKQLE 440
L A+Y +++G L +V +D Y T G + AEL V+ L
Sbjct: 369 ETRLWAS----AKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLR 424
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
L V+ + A+F E++ W +N EV R+ IS G H L I
Sbjct: 425 KLP--RKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQC 482
Query: 501 RPEDEGDYTFV 511
ED G F+
Sbjct: 483 CLEDVGQVAFM 493
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTL 1105
AP FLT L ++ V GY + +C V G P P V W K+ + ED ++I + QG L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
I P D G Y C A N +G + + +L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 55.5 bits (132), Expect = 3e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 1045 RMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF--LITNYQGV 1102
++ P+F+ + V G A C + G P P++ W K+ + KF L G+
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
L L IR S D G Y C VN LG A A +L ++ P
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Score = 54.3 bits (129), Expect = 6e-07
Identities = 52/245 (21%), Positives = 87/245 (35%), Gaps = 6/245 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G L +S +KW ++P KY G L + D Y
Sbjct: 3195 EVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELT 386
+ D+ L V P + L +++ G + E+S + A V W K G E
Sbjct: 3255 SCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELS-KAAPVEWRK-GSETL 3312
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIA 446
R+ RY ++DG L + D Y + + A L + + +
Sbjct: 3313 RDGD---RYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLR 3369
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
A +CE+S + +W K +R R ++ G +L I + D G
Sbjct: 3370 HQESIEGATATLRCELS-KAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAG 3428
Query: 507 DYTFV 511
+Y+ V
Sbjct: 3429 EYSCV 3433
Score = 53.1 bits (126), Expect = 1e-06
Identities = 81/367 (22%), Positives = 136/367 (37%), Gaps = 65/367 (17%)
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEM-AVEVSEEGAQVMWMKDGVELTREDSFKARYRF 397
L + + +T L++Q+V G V V + V W KDG L +D Y
Sbjct: 5119 LLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD----HYMI 5174
Query: 398 KKDGKR-HILIFSDVVQEDRGRYQVITNGGQ----CEAELIVE----------------- 435
+D + H LI + VV D G Y+ + +AEL V+
Sbjct: 5175 NEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSS 5234
Query: 436 ---------------------EKQL-EVLQDIADLTVKASEQ-AVFKCEVSDEKVTGK-W 471
E QL +V++++ DL V + A F+ +V W
Sbjct: 5235 YFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYW 5294
Query: 472 YKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY-TFVPDGYALSLSAKLNFLEIKV 530
+K+G + S I ++ H L I V ED G Y ++ + + S+ L ++
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSAR--LLVRG 5352
Query: 531 EYVPKQEPPK-IHLDCSGKTSENAIV---VVAGNKLRLDVSITGEPPPVATWLKGDE--- 583
P+++P +H V G+ + V + G P P WL+ +
Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERG 5412
Query: 584 ---VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPD 640
+ T G T + S V+ R+ +G YT +N G+ + S L V +P
Sbjct: 5413 VLWIGPDTPGYT-VASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPK 5471
Query: 641 PPEAVRI 647
E ++
Sbjct: 5472 VEEQEKV 5478
Score = 52.4 bits (124), Expect = 2e-06
Identities = 53/197 (26%), Positives = 81/197 (41%), Gaps = 19/197 (9%)
Query: 443 QDIADLTVKASEQAVFKCEVSDE-KVTGKWYKNG--VEVRPSKRITISHVGRFHKLVIDD 499
+++AD T + E C V+ K WYK+G V+V P I I L++D
Sbjct: 6018 EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPH-HILIEDPDGSCALILDS 6076
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
+ D G Y +A S + + L + VP + K+ A V G
Sbjct: 6077 LTGVDSGQYMC----FAASAAGNCSTLGKILVQVPPRFVNKVR----------ASPFVEG 6122
Query: 560 NKLRLDVSITGEPPPVATWLKGDEVFTT-TEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+ +I G P P W K + TT + +T E R VI +A +ED G Y
Sbjct: 6123 EDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYEC 6182
Query: 619 KVTNPVGEDVASIFLQV 635
++ N +G AS L++
Sbjct: 6183 ELVNRLGSARASAELRI 6199
Score = 52.0 bits (123), Expect = 3e-06
Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 15/195 (7%)
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSF---VIESAQRED 612
VV G + L ++ +P ATW K E +R+ +F I ED
Sbjct: 7474 VVLGQSVTLACQVSAQPAAQATWSKDG---APLESSSRVLISATLKNFQLLTILVVVAED 7530
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTG 672
G YT V+N +G + L+ + P I V D +LVW+P G PVT
Sbjct: 7531 LGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYG--PVT- 7587
Query: 673 YLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM 732
Y+V+ +G W L ++F + Y ++K+ G Y R V+ G+ S ++ +
Sbjct: 7588 YIVQCSLEGGS-WTTLASDIF-DCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVL 7645
Query: 733 PIAPTSEPLHLIVED 747
P HL E+
Sbjct: 7646 ----LGGPSHLASEE 7656
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/93 (36%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED--PKFLITNYQGVLT 1104
AP FL V G A C V G P+P V W K+ + E P+ +
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L IR P D GTY RA N LG A A L V
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 49.7 bits (117), Expect = 2e-05
Identities = 44/188 (23%), Positives = 74/188 (39%), Gaps = 9/188 (4%)
Query: 450 VKASEQAVFKCE-VSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
V + A C+ V + W K+ V R ++ G ++L I D+ D G Y
Sbjct: 21 VSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQY 80
Query: 509 TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSI 568
A + L++ E ++ P L +I V G++ +
Sbjct: 81 VCRARNAIGEAFAAVG-LQVDAEAACAEQAPHFLL------RPTSIRVREGSEATFRCRV 133
Query: 569 TGEPPPVATWLKGDEVFTTTEG-RTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGED 627
G P P +W K +G R R+E+ + S+ I +A+ D G Y ++ NP+G
Sbjct: 134 GGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAA 193
Query: 628 VASIFLQV 635
A+ L V
Sbjct: 194 SAAAALVV 201
Score = 47.8 bits (112), Expect = 6e-05
Identities = 60/255 (23%), Positives = 89/255 (34%), Gaps = 21/255 (8%)
Query: 868 PRPQVVWTKGGAPL--DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATI 925
P + W GA + D S V +R A +GE + + A+
Sbjct: 4460 PVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR----DAVASA 4515
Query: 926 RIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYER 985
R+ V+ PP + V + W AP DG + GY V+ + T +W +E
Sbjct: 4516 RLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHEL 4575
Query: 986 NRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFR 1045
C V L G Y FRV G + P T R+ + P
Sbjct: 4576 VPGPECVVDGLAPGETYRFRVAAVGPVGAGE-PVHLPQTVRLAEPPKPVPPQP------- 4627
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105
AP+ R V AG +L V +V+W K I+ +F + + L
Sbjct: 4628 SAPE------SRQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPGGRFEVVSQGRQQML 4680
Query: 1106 NIRRPSPFDAGTYTC 1120
I+ + D G Y C
Sbjct: 4681 VIKGFTAEDQGEYHC 4695
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 1059 VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLI-TNYQGVLTLNIRRPSPFDAGT 1117
V G A L+C V G PKP+ VW K+ + E + ++ + Q L I D G
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGL 308
Query: 1118 YTCRAVNELGEALAECKLEVRVP 1140
YTC A N +G+ + + VR P
Sbjct: 309 YTCTASNLVGQTYSSVLVVVREP 331
Score = 47.4 bits (111), Expect = 8e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP-KFLITNYQGVLTLN 1106
P F L D G + L C V G PKP + W K+ ++ DP LI + G L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
+ + D+G Y C A + G K+ V+VP
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107
Score = 46.2 bits (108), Expect = 2e-04
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 1033 TFKPFEYKEHDFRMA--PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRE 1090
T + + Y+ D A P + D G +A + G P+P V W K+ +++ +
Sbjct: 6340 TQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVD 6399
Query: 1091 DPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
+ +L +R + DAG YTC A N G+ L CK E+ V
Sbjct: 6400 STRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVL--CKAELLV 6446
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQGVLTL 1105
AP FL L D VV G S L C V P + W K+ + + LI+ + L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521
Query: 1106 NIRRPSPFDAGTYTCRAVNELG 1127
I D G YTC N LG
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALG 7543
Score = 44.3 bits (103), Expect = 7e-04
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 16/136 (11%)
Query: 1014 LSDSPGVSKNTARILKTGITFKPFEYKE------HDFRMAPKFLTPLIDRVVVAGYSAAL 1067
+S++ G + ++AR+L G P E +E H+ + P+ L + V G S
Sbjct: 5335 ISNAMGAAYSSARLLVRG----PDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITF 5390
Query: 1068 NCAVRGHPKPKVVWMKNKMEI------REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
+ V G P P V W++ + E + P + + + +L + GTYTC
Sbjct: 5391 SVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCI 5450
Query: 1122 AVNELGEALAECKLEV 1137
A N G+AL L V
Sbjct: 5451 ASNAAGQALCSASLHV 5466
Score = 42.4 bits (98), Expect = 0.003
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Query: 549 TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
T A VV G L I G P P +W K D+ R R+ + D I
Sbjct: 14 TRPKAFVVSVGKDATLSCQIVGNPTPQVSWEK-DQQPVAAGARFRLAQDGDLYRLTILDL 72
Query: 609 QREDEGRYTIKVTNPVGEDVASIFLQV 635
D G+Y + N +GE A++ LQV
Sbjct: 73 ALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 40.4 bits (93), Expect = 0.010
Identities = 63/268 (23%), Positives = 103/268 (38%), Gaps = 37/268 (13%)
Query: 873 VWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
+WT GG + +SR + VR+AA SD+GE SV+ K + +R R
Sbjct: 2769 MWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAA 2828
Query: 932 KAGPPINVMVKEVW-GTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTS 990
P +++ W VE + + + +KA +K+ ++ V E
Sbjct: 2829 IIKP-----LEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEG----- 2878
Query: 991 CTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKF 1050
T++ L++ + E C + SK+TA + H A F
Sbjct: 2879 -TMAMLVIRGAS-LKDAGEYTCEVE----ASKSTASL--------------HVEEKANCF 2918
Query: 1051 LTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110
L + V +A C HP V W K +E+R K + L L I
Sbjct: 2919 TEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISAL 2977
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEVR 1138
D+ TYTC ++G+A + +L V+
Sbjct: 2978 EKADSDTYTC----DIGQAQSRAQLLVQ 3001
Score = 40.0 bits (92), Expect = 0.013
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAA-LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P+ + L D V G A V+G+P P++ W K+ + +T+ + + TL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
I + D+G Y N +G A + +L VR P
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGP 5353
Score = 39.3 bits (90), Expect = 0.022
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
FL L D + AL C V P+ VVW K+ +++ K+ + G L +
Sbjct: 2649 FLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHD 2707
Query: 1110 PSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
SP DAG YTC +E E + VRV
Sbjct: 2708 VSPEDAGLYTCHVGSE------ETRARVRV 2731
Score = 38.9 bits (89), Expect = 0.028
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 556 VVAGNKL-RLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 614
V G +L + + + G P P W K + T + +K++ + I S RED G
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKI-LHTLEIISVTREDSG 5329
Query: 615 RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGE 652
+Y ++N +G +S L +V PD PE + V E
Sbjct: 5330 QYAAYISNAMGAAYSSARL-LVRGPDEPEEKPASDVHE 5366
Score = 38.1 bits (87), Expect = 0.048
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 353 EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVV 412
E +QV G+ V + +EV E +V+W K G+E + R+ G++ +L+
Sbjct: 4631 ESRQVAAGEDVSLELEVVAEAGEVIWHK-GMERIQPGG---RFEVVSQGRQQMLVIKGFT 4686
Query: 413 QEDRGRYQV-ITNGGQCEA 430
ED+G Y + G C A
Sbjct: 4687 AEDQGEYHCGLAQGSICPA 4705
Score = 37.7 bits (86), Expect = 0.063
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Query: 344 PPVLIVTPLEDQQVFVGDRVEM-AVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGK 402
PP + VT +ED Q G + A+ + V W KD V+L DS R +++G
Sbjct: 6356 PPSMQVT-IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLV--DS--TRLSQQQEGT 6410
Query: 403 RHILIFSDVVQEDRGRYQVI--TNGGQ--CEAELIV 434
+ L+ V +D G Y + GGQ C+AEL+V
Sbjct: 6411 TYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 6446
Score = 36.2 bits (82), Expect = 0.18
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 6/125 (4%)
Query: 841 RLPRHLRQTYIRKV--GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDT 895
R P LR+ V G+ + L +P Q W+K GAPL++S + +F
Sbjct: 7461 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 7520
Query: 896 VFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQA 955
+ + A D G Y SV T T +R E+ + EV+ L+ W+
Sbjct: 7521 LTILVVVA-EDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKP 7579
Query: 956 PKDDG 960
+ G
Sbjct: 7580 VESYG 7584
Score = 35.8 bits (81), Expect = 0.24
Identities = 36/125 (28%), Positives = 49/125 (39%), Gaps = 19/125 (15%)
Query: 809 FRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP 868
F VG+ + + A A +R P IR+ T+ +VG G P
Sbjct: 92 FAAVGLQVDAEAACAEQAPHFLLR----PTSIRVREGSEATFRCRVG----------GSP 137
Query: 869 RPQVVWTKGGAPL---DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATI 925
RP V W+K G L D RV V + +R A D G YE V+ EN A+
Sbjct: 138 RPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYE--VRAENPLGAASA 195
Query: 926 RIRVV 930
+V
Sbjct: 196 AAALV 200
Score = 35.4 bits (80), Expect = 0.31
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 2/103 (1%)
Query: 1028 LKTGITFKPFEY-KEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
+K FK ++ KE + P F D G + L C V + W+K+ +
Sbjct: 4877 VKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGV 4936
Query: 1087 EIREDPKFLITNY-QGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128
E+ + I G +L I DAG YTC+ N+ G+
Sbjct: 4937 ELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 35.4 bits (80), Expect = 0.31
Identities = 45/209 (21%), Positives = 85/209 (40%), Gaps = 27/209 (12%)
Query: 271 GNKIKLMVEISD-PDLTLKWFKNGQEIKPSSKYVF-ENVGKKRILTINKCTLADDAAYE- 327
G +KL ++ P + W+K+G+ ++ ++ E+ L ++ T D Y
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 328 -VAVKDEKCFT--ELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGA---QVMWMKD 381
A C T ++ V+ PP V + G+ + + EGA Q+ W KD
Sbjct: 6088 FAASAAGNCSTLGKILVQVPP-RFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKD 6144
Query: 382 GVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV-ITN---GGQCEAELIVEEK 437
G LT + F+ + +L+ +ED G Y+ + N + AEL ++
Sbjct: 6145 GALLTTGNKFQTLSEPRSG--LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Query: 438 QLEVLQD---------IADLTVKASEQAV 457
L+ + + D T++ ++Q V
Sbjct: 6203 MLQAQEQCHREQLVAAVEDTTLERADQEV 6231
Score = 35.4 bits (80), Expect = 0.31
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDT---VFFVRQAARSDSGEYE 911
GE +G P PQ+ W K GA L T S+ + V +R A++ D G YE
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Query: 912 LSV--QIENMKDTATIRIR 928
+ ++ + + +A +RI+
Sbjct: 6182 CELVNRLGSARASAELRIQ 6200
Score = 34.7 bits (78), Expect = 0.53
Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 1064 SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
S L+C R PK V W K+ + KF ++ + L I R P DAG Y C+A
Sbjct: 2485 SVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA 2542
Score = 34.7 bits (78), Expect = 0.53
Identities = 79/384 (20%), Positives = 135/384 (35%), Gaps = 62/384 (16%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
QV G + L +E+ + W K + I+P ++ + G++++L I T D Y
Sbjct: 4634 QVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEG-AQVMWMKDGVEL 385
+ + L V + + E ++EG ++W
Sbjct: 4694 HCGLAQGS------ICPAAATFQVALSPASVDEAPQPSLPPEAAQEGDLHLLW------- 4740
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+A R ++ + L + E+ GR Q + EAE + + L
Sbjct: 4741 ------EALARKRRMSREPTLDSISELPEEDGRSQRLPQ----EAEEVAPD--LSEGYST 4788
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGK------WYKNGVEVRPSKRITISHVGR-------- 491
AD + + + DE G K G RP S VG
Sbjct: 4789 ADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAG---RPGTSPLASKVGAPAAPSVKP 4845
Query: 492 --------FHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHL 543
+ + D+ +D GD + D A+ + A +++ E ++ P H
Sbjct: 4846 QQQQEPLAAVRPPLGDLSTKDLGDPSM--DKAAVKIQAAFKGYKVRKEMKQQEGPMFSHT 4903
Query: 544 DCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCS-S 602
G T G+ LRL+ + + A WLK D V T I++ D + S
Sbjct: 4904 --FGDTEAQV-----GDALRLECVVASKADVRARWLK-DGVELTDGRHHHIDQLGDGTCS 4955
Query: 603 FVIESAQREDEGRYTIKVTNPVGE 626
+I R D G YT +V+N G+
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 34.3 bits (77), Expect = 0.69
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+F L D V+ G +A L C + P V W +R K+ + +L L +R
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVR 3244
Query: 1109 RPSPFDAGTYTC 1120
P D+G Y+C
Sbjct: 3245 NLRPQDSGRYSC 3256
Score = 34.3 bits (77), Expect = 0.69
Identities = 91/396 (22%), Positives = 151/396 (38%), Gaps = 51/396 (12%)
Query: 322 DDAAYEV--AVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEM-AVEVSEEGAQVMW 378
D AA ++ A K K E+ +E P+ T D + VGD + + V S+ + W
Sbjct: 4873 DKAAVKIQAAFKGYKVRKEMKQQEGPMFSHT-FGDTEAQVGDALRLECVVASKADVRARW 4931
Query: 379 MKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRY--QVITNGGQC--EAELIV 434
+KDGVELT D DG +LI + + + D G Y QV GQ A ++V
Sbjct: 4932 LKDGVELT--DGRHHHIDQLGDGTCSLLI-TGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988
Query: 435 EEKQLEVLQ----DIADLTVKASEQA--VFK----CEVSDEKVTGKWYKNGVEVR-PSKR 483
+ E ++ D +A+ + +F+ EVSDE++ + E P+
Sbjct: 4989 SGSESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW 5048
Query: 484 ITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEI---KVEYVPKQEPPK 540
T F + + + + F L + ++ +E +VE +E P
Sbjct: 5049 QTYREDEHFICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPA 5108
Query: 541 IHLDC----SGKTSENAIVVVA---------GNKLRLDVSITGEPPPVATWLKGDEVFTT 587
+ S TS+ A V + G + D +TG+P P W K ++
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 5168
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ E + +I + D G Y N +G L+ V +
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELR----------VDL 5218
Query: 648 TSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQ 683
TS D A E Y + GYL R+++G++
Sbjct: 5219 TSTDYDTAADATESSSYFSAQ---GYLSSREQEGTE 5251
Score = 33.9 bits (76), Expect = 0.91
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 935 PPINVMVKEVWGTNALVEWQ-APKDDGNSEIMGYFVQKADKKTMEWFNVYERN--RHTSC 991
PP++ +VK ++ ++ W P + I GY V+K T W +E
Sbjct: 515 PPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPEL 574
Query: 992 TVSDLIVGNEYYFRVYTENICGLS 1015
TV+D+ + FRV N G S
Sbjct: 575 TVADVAEEGNFQFRVSALNSFGQS 598
Score = 33.9 bits (76), Expect = 0.91
Identities = 24/105 (22%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
+P PP + + T+E G ++L +TG P PV +W K +
Sbjct: 6008 LPVWRPPDFEEELADCTAE------LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHI 6061
Query: 593 RIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG--EDVASIFLQV 635
IE + +++S D G+Y + G + I +QV
Sbjct: 6062 LIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
Score = 33.9 bits (76), Expect = 0.91
Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Query: 445 IADLTVKASEQAVFKCEVS-DEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPE 503
I D+ + A F+ + D + + WYK+ V++ S R++ G + LV+ V +
Sbjct: 6363 IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASK 6422
Query: 504 DEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQE 537
D G YT + + K L + + P E
Sbjct: 6423 DAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSE 6456
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Query: 1061 AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTC 1120
AG SA L+C V + +V W K+ ++ K I + L +++ DAG YTC
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 1121 RA 1122
A
Sbjct: 1331 EA 1332
Score = 33.5 bits (75), Expect = 1.2
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 1049 KFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIR 1108
+FL L + V G +A L C + V W K +++ K+ + L +R
Sbjct: 3980 RFLRELQHQEVDEGGTAHLCCEL-SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVR 4038
Query: 1109 RPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
DAG YTC + G + L VRVP+
Sbjct: 4039 GVEQEDAGDYTC----DTGHTQSMASLSVRVPR 4067
Score = 33.1 bits (74), Expect = 1.5
Identities = 58/298 (19%), Positives = 111/298 (37%), Gaps = 39/298 (13%)
Query: 833 EIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS-RVHVRTS 891
+++EP + L ++ + + + + +V W K G L +S +V +
Sbjct: 1342 DVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAV 1401
Query: 892 DFDTVFFVRQAARSDSGEYELSVQIENMKDTATI-RIRVVEKAGPPINVMVKEVWGTNAL 950
V+QA ++D+GEY + + + + +VV P++ V+ G +
Sbjct: 1402 GCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTT 1461
Query: 951 VEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI------VGNEYYF 1004
+ + + +E+M Y K KK F+ R CT ++ V EY
Sbjct: 1462 LSCEVAQ--AQTEVMWY---KDGKKLS--FSSKVRMEAVGCTRRLVVQQAGQAVAGEYSC 1514
Query: 1005 RVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYS 1064
++ LS V++ A K + + + AG S
Sbjct: 1515 EAGSQR---LSFHLHVAEPKAVFAKEQPASREVQAE--------------------AGTS 1551
Query: 1065 AALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRA 1122
A L+C V + +V W K+ ++ K + L ++ DAG Y+C+A
Sbjct: 1552 ATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA 1608
Score = 33.1 bits (74), Expect = 1.5
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 865 QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVR--QAARSDSGEY 910
+G P P++ W K G PL T+ H+R +D + + R DSG+Y
Sbjct: 5285 KGYPAPRLYWFKDGQPL-TASAHIRMTDKKILHTLEIISVTREDSGQY 5331
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 559 GNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
G + + I G+P P TW K D V R ++ S V+ +D G YT
Sbjct: 6371 GGTAQFEAIIEGDPQPSVTWYK-DSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTC 6429
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEA 644
N G+ + L V+ + P++
Sbjct: 6430 LAQNTGGQVLCKAELLVLGGDNEPDS 6455
Score = 32.3 bits (72), Expect = 2.6
Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRR 1109
F PL D V L C + P V W+K+ +E+R I +L I R
Sbjct: 2168 FSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYR 2226
Query: 1110 PSPFDAGTYTCRA 1122
D G Y C A
Sbjct: 2227 CEFADQGVYVCDA 2239
Score = 31.6 bits (70), Expect = 4.5
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 1061 AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTC 1120
AG SA L+C V + +V W K+ ++ K + L +++ DAG Y+C
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSC 1698
Query: 1121 RA 1122
A
Sbjct: 1699 EA 1700
Score = 30.8 bits (68), Expect = 7.7
Identities = 33/122 (27%), Positives = 48/122 (39%), Gaps = 4/122 (3%)
Query: 818 GRSEPATLAQPVTIREI--AEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWT 875
G S A LA RE AE P +T G+ L G+P+P+ VW
Sbjct: 213 GTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWK 272
Query: 876 KGGAPLDTSRVHVRTSDFDTVFFVR--QAARSDSGEYELSVQIENMKDTATIRIRVVEKA 933
K G + R HV D F ++ +SD G Y + + +++ + V E A
Sbjct: 273 KDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPA 332
Query: 934 GP 935
P
Sbjct: 333 VP 334
Score = 30.8 bits (68), Expect = 7.7
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 1061 AGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTC 1120
AG SA L+C V + +V W K+ ++ K + L +++ DAG Y+C
Sbjct: 904 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 1121 RA 1122
A
Sbjct: 963 EA 964
Score = 30.8 bits (68), Expect = 7.7
Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 871 QVVWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEY 910
+V+W K G L +S +VHV V+QA ++D+G+Y
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDY 1052
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 125 bits (313), Expect = 3e-28
Identities = 99/357 (27%), Positives = 153/357 (42%), Gaps = 37/357 (10%)
Query: 268 VDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYE 327
+ G +E+S +T +W + G ++ P K + G + L +N LAD
Sbjct: 1551 ISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVS 1610
Query: 328 VAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTR 387
+C L V+E PV IV D +V GD E+S+ A V W KDG LT
Sbjct: 1611 FTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWEKDGNALTP 1670
Query: 388 EDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQC-EAELIVEEKQLEVLQDIA 446
R R + G R +L D G Y + L V E+ + VL ++
Sbjct: 1671 ----SPRLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELR 1726
Query: 447 DLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506
++ + + A F+C VS+ + TG+W G +RP R+ I G+ H LV+ ++R ED G
Sbjct: 1727 SVSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAG 1786
Query: 507 DYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDV 566
+ F G A SL+ ++VE +P Q C E ++V G + L+V
Sbjct: 1787 EVRF-QAGPAQSLAL------LEVEALPLQM-------CRHPPREKTVLV--GRRAVLEV 1830
Query: 567 SITGEPPPVATWLK-------GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRY 616
+++ V WL+ GD+ + G T S VI + ED+G Y
Sbjct: 1831 TVSRSGGHVC-WLREGAELCPGDKYEMRSHGPTH--------SLVIHDVRPEDQGTY 1878
Score = 121 bits (304), Expect = 3e-27
Identities = 79/268 (29%), Positives = 124/268 (46%), Gaps = 8/268 (2%)
Query: 268 VDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYE 327
V G+ E+S PD + W +NG + P + G RILT+ C L D
Sbjct: 1371 VHEGDDATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVT 1430
Query: 328 VAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ--VMWMKDGVEL 385
+ L V+E +L + L+D + G V + VE GA V W++ G L
Sbjct: 1431 LRAGSTATSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPL 1490
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+ +R +DG H L V+ D+G Y ++ + A L V +QL VL+ +
Sbjct: 1491 PHD----SRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLRPL 1546
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
D+T+ A F+ E+S E VTG+W + GV++ P + I G H+LV++ + D
Sbjct: 1547 EDVTISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADS 1606
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYV 533
G +F D +L +A+L E+ V V
Sbjct: 1607 GCVSFTAD--SLRCAARLIVREVPVTIV 1632
Score = 97.8 bits (242), Expect = 5e-20
Identities = 71/244 (29%), Positives = 109/244 (44%), Gaps = 6/244 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G+ E+S + W K+G + PS + + +G +R+L + +C +D Y
Sbjct: 1639 EVTEGDTATFECELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTY 1698
Query: 327 EVAVKDEKCF-TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVEL 385
AV + L V+E V +++ L GD VSE W G L
Sbjct: 1699 SCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPL 1758
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQ-D 444
AR R +++GK+HIL+ S++ ED G + Q A L VE L++ +
Sbjct: 1759 RP----GARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHP 1814
Query: 445 IADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPED 504
+ TV +AV + VS W + G E+ P + + G H LVI DVRPED
Sbjct: 1815 PREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPED 1874
Query: 505 EGDY 508
+G Y
Sbjct: 1875 QGTY 1878
Score = 95.1 bits (235), Expect = 3e-19
Identities = 100/410 (24%), Positives = 166/410 (40%), Gaps = 46/410 (11%)
Query: 252 VKKSAAFTKKLDPAYQV---DR-------GNKIKLMVEISDPDLTLKWFKNGQEIKPSSK 301
V+ SAA T + P + + DR ++ L E+S D W+K+GQ+++ S
Sbjct: 702 VQDSAALTIQESPVHILSPQDRVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESEL 761
Query: 302 YVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFV-- 359
V + G+K L + + + D +E + F + V++PPV IV P E VFV
Sbjct: 762 LVVKMDGRKHRLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPRE--HVFVHA 819
Query: 360 --GDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRG 417
+ V +A EV E A V W KDG E+ D + +G L+ D G
Sbjct: 820 ITSECVMLACEVDREDAPVRWYKDGQEVEESDFVV----LENEGPHRRLVLPATQPSDGG 875
Query: 418 RYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKA--SEQAVFKCEVSDEKVTGKWYKNG 475
+Q + + + + ++ + V A E+ V CE+ +W K+G
Sbjct: 876 EFQCVAGDECAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDG 935
Query: 476 VEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPK 535
EV S + + +LV+ V+ ED G+Y D + S + + +++ Y P+
Sbjct: 936 EEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIY-PR 994
Query: 536 QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIE 595
E ++ V + L ++ E PV + G EV +E
Sbjct: 995 DEV--------------TLIAVTLECVVLMCELSREDAPVRWYKDGLEV--EESEALVLE 1038
Query: 596 KRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAV 645
+ V+ +AQ ED G + G+D A V V PPE +
Sbjct: 1039 RDGPRCRLVLPAAQPEDGGEFVC----DAGDDSAFF---TVTVTAPPERI 1081
Score = 94.4 bits (233), Expect = 6e-19
Identities = 88/351 (25%), Positives = 138/351 (39%), Gaps = 26/351 (7%)
Query: 274 IKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE 333
+ LM E+S D ++W+K+G E++ S V E G + L + D + D+
Sbjct: 1007 VVLMCELSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDD 1066
Query: 334 KCFTELFVKEPPVLIVTPLE---DQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDS 390
F + V PP IV P D RVE+ EV+ G+QV W KDG+E+ D+
Sbjct: 1067 SAFFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDA 1126
Query: 391 FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVL---QDIAD 447
+ +G L ED G Y T +I+ E ++ L +
Sbjct: 1127 L----QLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPPVQFLALETTPSP 1182
Query: 448 LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGD 507
L V E V CE+S W NG V+ + + + G L I P G
Sbjct: 1183 LCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGL 1242
Query: 508 YTFVPDGY--ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 565
YT A SLS + E V V + + ++ + G L L
Sbjct: 1243 YTCQSGAAPGAPSLSFTVQVAEPPVRVV------------APEAAQTRVRSTPGGDLELV 1290
Query: 566 VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRY 616
V ++G PV + G+ + ++GR ++E+ ++ A+ D G Y
Sbjct: 1291 VHLSGPGGPVRWYKDGERL--ASQGRVQLEQAGARQVLRVQGARSGDAGEY 1339
Score = 85.5 bits (210), Expect = 3e-16
Identities = 95/407 (23%), Positives = 163/407 (40%), Gaps = 52/407 (12%)
Query: 289 WFKNGQEIKPSS----------KYVFENVGKKRILTINKCTLADDAAYE----VAVKDEK 334
WF NG+E+K + +Y E G + L ++ D A V+D
Sbjct: 647 WFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSA 706
Query: 335 CFTELFVKEPPVLIVTPLEDQQVF--VGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFK 392
T ++E PV I++P + + +RV + E+S W KDG ++ +
Sbjct: 707 ALT---IQESPVHILSPQDRVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESELLV 763
Query: 393 ARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKA 452
K DG++H LI + +D G ++ T G + V++ + ++ + V A
Sbjct: 764 V----KMDGRKHRLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPREHVFVHA 819
Query: 453 --SEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF 510
SE + CEV E +WYK+G EV S + + + G +LV+ +P D G++
Sbjct: 820 ITSECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQC 879
Query: 511 VPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITG 570
V + + + + Y SGK V VA +L V +T
Sbjct: 880 VAGDECAYFTVTITDVSSWIVYP------------SGK------VYVAAVRLER-VVLTC 920
Query: 571 E---PPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
E P W K G+EV + ++K V+ + Q ED G Y ++ +
Sbjct: 921 ELCRPWAEVRWTKDGEEVVESPA--LLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESAS 978
Query: 627 DVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGY 673
++ V + P + V + +V + +L+ E D PV Y
Sbjct: 979 FTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDA--PVRWY 1023
Score = 80.5 bits (197), Expect = 8e-15
Identities = 82/331 (24%), Positives = 136/331 (41%), Gaps = 37/331 (11%)
Query: 344 PPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSF------KARYRF 397
P +V LED QV+ G+ ++++S Q W +G EL + RYR
Sbjct: 614 PTARLVAGLEDVQVYDGEDAVFSLDLSTI-IQGTWFLNGEELKSNEPEGQVEPGALRYRI 672
Query: 398 KKDGKRHILIFSDVVQEDRGRYQVITNGG-QCEAELIVEEKQLEVL--QDIADLTVKASE 454
++ G +H LI V +D G + G Q A L ++E + +L QD LT SE
Sbjct: 673 EQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDRVSLTFTTSE 732
Query: 455 QAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDG 514
+ V CE+S WYK+G +V S+ + + GR H+L++ + + +D G++ +G
Sbjct: 733 RVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG 792
Query: 515 YALSLSAKLNFLEIKVEYVPKQ-EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPP 573
+ F + V+ P P+ H+ TSE + L + E
Sbjct: 793 VSA-------FFGVTVQDPPVHIVDPREHVFVHAITSECVM---------LACEVDREDA 836
Query: 574 PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
PV + G EV +E V+ + Q D G + G++ A +
Sbjct: 837 PVRWYKDGQEV--EESDFVVLENEGPHRRLVLPATQPSDGGEFQC----VAGDECAYFTV 890
Query: 634 QVVDVPD----PPEAVRITSVGEDWAILVWE 660
+ DV P V + +V + +L E
Sbjct: 891 TITDVSSWIVYPSGKVYVAAVRLERVVLTCE 921
Score = 75.1 bits (183), Expect = 4e-13
Identities = 70/272 (25%), Positives = 109/272 (40%), Gaps = 16/272 (5%)
Query: 271 GNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYE--- 327
G + L E+S + W NG+ ++ G +R+L I A Y
Sbjct: 1188 GEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQS 1247
Query: 328 -VAVKDEKCFTELFVKEPPVLIVTPLEDQQVFV----GDRVEMAVEVSEEGAQVMWMKDG 382
A + V EPPV +V P E Q V G +E+ V +S G V W KDG
Sbjct: 1248 GAAPGAPSLSFTVQVAEPPVRVVAP-EAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDG 1306
Query: 383 VELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQL-EV 441
L + R + ++ G R +L D G Y + VEE L ++
Sbjct: 1307 ERLASQ----GRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKL 1362
Query: 442 LQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVR 501
+ ++ LTV + A F+CEVS W +NG V P ++ ++ G L + +
Sbjct: 1363 VSELTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQ 1422
Query: 502 PEDEGDYTFVPDGYALSLSAKLNFLEIKVEYV 533
D G T A SA+L+ E ++ ++
Sbjct: 1423 LGDAGTVTLRAGSTA--TSARLHVRETELLFL 1452
Score = 67.4 bits (163), Expect = 7e-11
Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 5/157 (3%)
Query: 280 ISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTEL 339
+S+ + T +W G+ ++P ++ GKK IL +++ D + L
Sbjct: 1742 VSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALL 1801
Query: 340 FVKEPPVLIVT-PLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
V+ P+ + P ++ V VG R + V VS G V W+++G EL D +Y +
Sbjct: 1802 EVEALPLQMCRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGD----KYEMR 1857
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVE 435
G H L+ DV ED+G Y L+VE
Sbjct: 1858 SHGPTHSLVIHDVRPEDQGTYCCQAGQDSTHTRLLVE 1894
Score = 58.5 bits (140), Expect = 3e-08
Identities = 52/246 (21%), Positives = 93/246 (37%), Gaps = 14/246 (5%)
Query: 273 KIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKD 332
+++L E++ ++W+K+G E++ S G R LT+ D Y +
Sbjct: 1098 RVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRH 1157
Query: 333 EKCFTELFVKEPPV---LIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTRED 389
E + + EPPV + T V G+ V ++ E+S GA V+W +G + +
Sbjct: 1158 EAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGE 1217
Query: 390 SFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAEL-----IVEEKQLEVLQD 444
+ +G R +L G Y + L + E V +
Sbjct: 1218 GLE----LHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPE 1273
Query: 445 IADLTVKASEQAVFKCEVSDEKVTG--KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRP 502
A V+++ + V G +WYK+G + R+ + G L + R
Sbjct: 1274 AAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARS 1333
Query: 503 EDEGDY 508
D G+Y
Sbjct: 1334 GDAGEY 1339
Score = 53.9 bits (128), Expect = 8e-07
Identities = 61/285 (21%), Positives = 116/285 (40%), Gaps = 42/285 (14%)
Query: 414 EDRGRYQVIT--NGGQC--EAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTG 469
+DRG Y + GQ +L V+E +L + + D+ + AV +C+V + ++
Sbjct: 312 KDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPT 371
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIK 529
W++ + P ++ G +L+I ++ +D+G Y G +++ + +K
Sbjct: 372 AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVAN----VTVK 427
Query: 530 VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
+ K+ P K+ + ENA+++V L+ + G W + E
Sbjct: 428 GPIL-KRLPRKLDV----LEGENAVLLVE----TLEAGVEGR------WSRDGE------ 466
Query: 590 GRTRIEKRVDCSS-------FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPP 642
E V C S V+ RED G T + N + + P PP
Sbjct: 467 -----ELPVICQSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPP 521
Query: 643 EAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMK 687
+ ++ +L W+PP P Y +ER++ GS+ W++
Sbjct: 522 ILAEMFKGHKNTVLLTWKPPEPAPETPFI-YRLERQEVGSEDWIQ 565
Score = 51.6 bits (122), Expect = 4e-06
Identities = 30/82 (36%), Positives = 36/82 (43%)
Query: 1059 VVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTY 1118
VV+G A L C V G P P VVW K ++ + L + P DAG Y
Sbjct: 23 VVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVY 82
Query: 1119 TCRAVNELGEALAECKLEVRVP 1140
CRA N GEA A + V P
Sbjct: 83 VCRARNAAGEAYAAAAVTVLEP 104
Score = 50.8 bits (120), Expect = 7e-06
Identities = 66/281 (23%), Positives = 110/281 (39%), Gaps = 22/281 (7%)
Query: 266 YQVDRGNKIKLMVEI-SDPDLTLKWFKNGQEIKPSSK-YVFENVGKKRILTINKCTLADD 323
+ V+ G K + P+ ++W G+ + P + ++ + +L + C D
Sbjct: 255 FWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDR 314
Query: 324 AAYEVAVKDEKCFT----ELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWM 379
Y A ++ T +L VKEP + PL+D + + +V W
Sbjct: 315 GLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWF 374
Query: 380 KDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG-QCEAELIVEEKQ 438
++ L +Y ++G LI + +D G Y G + A + V+
Sbjct: 375 REDQRLLP----CRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGPI 430
Query: 439 LEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVID 498
L+ L L V E AV E + V G+W ++G E+ I S G H LV+
Sbjct: 431 LKRLP--RKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPV---ICQSSSGHMHALVLP 485
Query: 499 DVRPEDEGDYTFVPDGYALSLSAKLNFLEIK-VEYVPKQEP 538
V ED G+ TF +L S L +K V++ P P
Sbjct: 486 GVTREDAGEVTF-----SLGNSRTTTLLRVKCVKHSPPGPP 521
Score = 50.4 bits (119), Expect = 9e-06
Identities = 96/415 (23%), Positives = 144/415 (34%), Gaps = 48/415 (11%)
Query: 26 PPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPT 85
PP P P E P SP + E VFL P S V G + V+ + G LP+ PT
Sbjct: 104 PPASDPELQPAERPLP--SPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGG--LPE-PT 158
Query: 86 IKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCD 145
+ W K + F+ + ++ L I L D G Y +
Sbjct: 159 LYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHA 218
Query: 146 SCGFNIDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDD 205
G + V P + E+ A ++ K V E K K +
Sbjct: 219 QAGALLQVHQPPESPPADPDEA----------PAPVVEPLKCAPKTFWVNEGKHAKFRCY 268
Query: 206 DDLGIP-PEI---WE---LLKGAKKSEYEK------IAFQYGITDLRGML---------K 243
+G P PEI WE LL ++ Y + Y RG+ +
Sbjct: 269 V-MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQ 327
Query: 244 RLKKAKVEVKKSAA-FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKY 302
L ++ VK+ FT+ L + G + L ++ + + WF+ Q + P KY
Sbjct: 328 TLSAVQLHVKEPRLRFTRPLQDVEGREHGIAV-LECKVPNSRIPTAWFREDQRLLPCRKY 386
Query: 303 VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDR 362
G R L I++ DD Y ++ + P+L P V G+
Sbjct: 387 EQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGPILKRLP-RKLDVLEGEN 445
Query: 363 VEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRG 417
+ VE E G + W +DG EL G H L+ V +ED G
Sbjct: 446 AVLLVETLEAGVEGRWSRDGEELPVICQ-------SSSGHMHALVLPGVTREDAG 493
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCS--SFVIESAQREDE 613
VV+G + L + GEPPPV W KG + +E R+ D + ++ +A D
Sbjct: 23 VVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASE---RLSFPADGAEHGLLLTAALPTDA 79
Query: 614 GRYTIKVTNPVGEDVASIFLQVVDVP 639
G Y + N GE A+ + V++ P
Sbjct: 80 GVYVCRARNAAGEAYAAAAVTVLEPP 105
Score = 41.6 bits (96), Expect = 0.004
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 9/103 (8%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRE---------DPKFLIT 1097
AP FLT + V+ G L C G P+P + W K+ M + E P
Sbjct: 127 APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED 186
Query: 1098 NYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
L L I D+G Y C A N G A A L+V P
Sbjct: 187 GPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQP 229
Score = 39.7 bits (91), Expect = 0.017
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLI-TNYQGVLTLNIRRPSPFDAGTYTC 1120
G A C V G P+P++ W + D + L+ + G L + D G Y C
Sbjct: 260 GKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVC 319
Query: 1121 RAVNELGEALAECKLEVRVPQ 1141
A N G+ L+ +L V+ P+
Sbjct: 320 AARNSAGQTLSAVQLHVKEPR 340
Score = 38.9 bits (89), Expect = 0.028
Identities = 54/217 (24%), Positives = 82/217 (37%), Gaps = 26/217 (11%)
Query: 450 VKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
V + +A KC V E W K G ++ S+R++ G H L++ P D G Y
Sbjct: 23 VVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVY 82
Query: 509 -----TFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGK--------TSENAIV 555
+ YA +A + LE P+ +P + L G T +
Sbjct: 83 VCRARNAAGEAYA---AAAVTVLEPPAS-DPELQPAERPLPSPGSGEGAPVFLTGPRSQW 138
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKG----DEVFTTTEGRTRIEKRVD----CSSFVIES 607
V+ G ++ L G P P W K DEV+ ++ + + D + I +
Sbjct: 139 VLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILA 198
Query: 608 AQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA 644
A+ D G Y N G A LQV P+ P A
Sbjct: 199 ARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPA 235
Score = 31.6 bits (70), Expect = 4.5
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 1/65 (1%)
Query: 1056 DRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
D V G +A C + V W K+ + P+ + L +RR P DA
Sbjct: 1637 DLEVTEGDTATFECEL-SQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDA 1695
Query: 1116 GTYTC 1120
GTY+C
Sbjct: 1696 GTYSC 1700
Score = 31.2 bits (69), Expect = 5.9
Identities = 27/88 (30%), Positives = 34/88 (38%), Gaps = 8/88 (9%)
Query: 1051 LTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110
LTPL V G A C V P V W++N + P+ + L +R
Sbjct: 1366 LTPL---TVHEGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGC 1421
Query: 1111 SPFDAGTYTCRAVNELGEALAECKLEVR 1138
DAGT T RA G +L VR
Sbjct: 1422 QLGDAGTVTLRA----GSTATSARLHVR 1445
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 124 bits (311), Expect = 5e-28
Identities = 98/378 (25%), Positives = 161/378 (42%), Gaps = 25/378 (6%)
Query: 274 IKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE 333
I V ++ ++ KW KNG EIK + K L I D A Y
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045
Query: 334 KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKA 393
L+V+ + ++D +V R EVSE V WMKD EL D
Sbjct: 3046 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITD---- 3101
Query: 394 RYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKAS 453
R + +K+ H L+ D G+Y V+ G A+L VE + + + ++ V
Sbjct: 3102 RIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3161
Query: 454 EQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHV--GRFHKLVIDDVRPEDEGDYTFV 511
++AV + EV+++ V WYK+G+E+ + +V R H++ I + R D G+YTFV
Sbjct: 3162 QRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV 3221
Query: 512 PDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGE 571
S++ YV EPP++ + + V +G R I+G
Sbjct: 3222 AGRNRSSVTL----------YVNAPEPPQVLQEL------QPVTVQSGKPARFCAVISGR 3265
Query: 572 PPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG--EDVA 629
P P +W K +++ +T + + + +IE A ED YT + N G A
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE-AFPEDAAVYTCEAKNDYGVATTSA 3324
Query: 630 SIFLQVVDVPDPPEAVRI 647
S+ ++V +V P + + +
Sbjct: 3325 SLSVEVPEVVSPDQEMPV 3342
Score = 123 bits (309), Expect = 9e-28
Identities = 99/374 (26%), Positives = 159/374 (42%), Gaps = 25/374 (6%)
Query: 250 VEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGK 309
V+ K+ FT++L ++ E S+P + +KW+K+G E+ KY + K
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRK 2227
Query: 310 KRILTINKCTLADDAAYE-VAVKDE--KCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366
L+I +D Y V V+DE K +L V+ V V L+D +V E+
Sbjct: 2228 VHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELE 2287
Query: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426
VS E + W + VEL +Y R L DV +ED+G Y + +G
Sbjct: 2288 CIVSPENIEGKWYHNDVELKSN----GKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2343
Query: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486
+ +L ++ + + +LQ ++D V + + +VS E V G W K+G EV+PS R+ I
Sbjct: 2344 KTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI 2403
Query: 487 SHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCS 546
+ H L+I+D+ ED G+Y+F LS S +++ + V
Sbjct: 2404 VIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV---------------- 2447
Query: 547 GKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIE 606
T + V+ G K L+ ++ W DE + I K VI
Sbjct: 2448 -ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK-QRLVIN 2505
Query: 607 SAQREDEGRYTIKV 620
DEG Y + V
Sbjct: 2506 RTHASDEGPYKLIV 2519
Score = 117 bits (293), Expect = 6e-26
Identities = 120/486 (24%), Positives = 203/486 (41%), Gaps = 48/486 (9%)
Query: 279 EISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE 338
E+S ++ W KNG EI+ S K+ GK L I + D A Y +++
Sbjct: 2904 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSAT 2963
Query: 339 LFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFK 398
L V P++I + L+D D + V V+ EG W+K+GVE+ D K + R K
Sbjct: 2964 LTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTD--KCQMRTK 3019
Query: 399 KDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVF 458
K H L +V D Y + A L VE + +E + I D+ V ++A+F
Sbjct: 3020 K--LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3077
Query: 459 KCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALS 518
+CEVS+ +T +W K+ E++ + RI I H+L+I R D G YT V G +
Sbjct: 3078 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVST 3137
Query: 519 LSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATW 578
+ ++++ + K+E I + A+V N+ +D A W
Sbjct: 3138 AKLFVEGRDVRIRSI-KKEVQVIE-------KQRAVVEFEVNEDDVD----------AHW 3179
Query: 579 LK-GDEVFTTTEGRTR--IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV 635
K G E+ + R + +E+R+ I ++ D G YT G + +S+ L
Sbjct: 3180 YKDGIEINFQVQERHKYVVERRI--HRMFISETRQSDAGEYTF----VAGRNRSSVTL-Y 3232
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNFEVFT 694
V+ P+PP+ ++ +P GKP ++ + + W K E
Sbjct: 3233 VNAPEPPQVLQ-----------ELQPVTVQSGKPARFCAVISGRPQPKISWYK--EEQLL 3279
Query: 695 ETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTT 754
T ++ + +G Y + + + + K +A TS L + V +V
Sbjct: 3280 STGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3339
Query: 755 LKWRPP 760
+ PP
Sbjct: 3340 MPVYPP 3345
Score = 115 bits (287), Expect = 3e-25
Identities = 132/509 (25%), Positives = 215/509 (42%), Gaps = 64/509 (12%)
Query: 159 DASGQSLESFKRTSEK---KSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIW 215
+ S + FKR +E+ ++ TA EL +K++ EE +K KD E+
Sbjct: 1992 EESEELRSKFKRRTEEGYYEAITAVELKS----RKKDESYEELLRKTKD--------ELL 2039
Query: 216 ELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLD--PAYQVDRGNK 273
K + E + +A + IT + K K+E+ S K + + V +G+
Sbjct: 2040 HWTKELTEEEKKALAEEGKIT-----IPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSD 2094
Query: 274 IKLMVEI-SDPDLTLKWFKNGQEIKPSSKYVF----ENVGKKRILTINKCTLADDAAYEV 328
V + PD +W+KNG +I+ S + + +NV + L I T D A+ V
Sbjct: 2095 AHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE---LVIRDVTAEDSASIMV 2151
Query: 329 A---VKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAV---EVSEEGAQVMWMKDG 382
+ E + + LI E Q V ++ MA E SE +V W KDG
Sbjct: 2152 KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDG 2211
Query: 383 VELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI---TNGGQCEAELIVEEKQL 439
+E+ D +YR D K H L + D Y + + A+LIVE +
Sbjct: 2212 MEVHEGD----KYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVV 2267
Query: 440 EVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDD 499
E ++++ D+ V S +C VS E + GKWY N VE++ + + TI+ L + D
Sbjct: 2268 EFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKD 2327
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V ED+G+Y+FV DG + K+ K P I S + V G
Sbjct: 2328 VTKEDQGEYSFVIDGKKTTCKLKM-----------KPRPIAILQGLSDQK------VCEG 2370
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+ ++L+V ++ E W+K G EV + I+K+ +IE +ED G Y+
Sbjct: 2371 DIVQLEVKVSLESVE-GVWMKDGQEVQPSDRVHIVIDKQ--SHMLLIEDMTKEDAGNYSF 2427
Query: 619 KVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ + + VDV P + V +
Sbjct: 2428 TIPALGLSTSGRVSVYSVDVITPLKDVNV 2456
Score = 111 bits (277), Expect = 4e-24
Identities = 74/266 (27%), Positives = 120/266 (45%), Gaps = 9/266 (3%)
Query: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFE 305
K ++K A KK V VE++ P++ ++W KNG ++ + KY
Sbjct: 2697 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2756
Query: 306 NVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEM 365
G L I C + D++ Y + L V+ V I+ +D V
Sbjct: 2757 VKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVET--VKIIKKPKDVTALENATVAF 2814
Query: 366 AVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNG 425
V VS + V W VE+ D ++R + K H L+ ++ D G Y +
Sbjct: 2815 EVSVSHDTVPVKWFHKSVEIKPSD----KHRLVSERKVHKLMLQNISPSDAGEYTAVVGQ 2870
Query: 426 GQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRIT 485
+C+A+L VE L + + + ++ V ++ A F+CEVS V W KNGVE+ S++
Sbjct: 2871 LECKAKLFVET--LHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFK 2928
Query: 486 ISHVGRFHKLVIDDVRPEDEGDYTFV 511
I G+ H+L+I + ED +YTFV
Sbjct: 2929 IVVQGKLHQLIIMNTSTEDSAEYTFV 2954
Score = 104 bits (259), Expect = 5e-22
Identities = 98/393 (24%), Positives = 166/393 (42%), Gaps = 39/393 (9%)
Query: 243 KRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKY 302
K +K KV KK A F E+S+PD+T++W K+ QE++ + +
Sbjct: 3062 KHIKDIKVLEKKRAMFE------------------CEVSEPDITVQWMKDDQELQITDRI 3103
Query: 303 VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDR 362
+ L I ++D Y V +LFV+ V I + ++ QV R
Sbjct: 3104 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3163
Query: 363 VEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVI 422
+ EV+E+ W KDG+E+ + + R+++ + + H + S+ Q D G Y +
Sbjct: 3164 AVVEFEVNEDDVDAHWYKDGIEINFQ--VQERHKYVVERRIHRMFISETRQSDAGEYTFV 3221
Query: 423 TNGGQCEAELIVEEKQL-EVLQDIADLTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVR 479
+ L V + +VLQ++ +TV++ + A F C V + K WYK +
Sbjct: 3222 AGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLS 3280
Query: 480 PSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYALSLSAKLNFLEIKVEYVPKQE- 537
+ H G+ + L++ + PED YT + Y ++ ++ +E+ P QE
Sbjct: 3281 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEM 3340
Query: 538 ---PPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGR-TR 593
PP I T V G R ++G V+ + K ++ + R T+
Sbjct: 3341 PVYPPAII------TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQ 3394
Query: 594 IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
E D I A EDEG YT +N VG+
Sbjct: 3395 FE---DTYQLEIAEAYPEDEGTYTFVASNAVGQ 3424
Score = 99.8 bits (247), Expect = 1e-20
Identities = 71/264 (26%), Positives = 127/264 (48%), Gaps = 11/264 (4%)
Query: 268 VDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
V G K L ++S PD+T +KW+ N ++IKP + G K+ L IN+ +D+ Y
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY 2515
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMW-MKDGVEL 385
++ V + L V++ + I+ L D V VE+S G V+W KD
Sbjct: 2516 KLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKD---- 2569
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+E ++Y+ + GK + L +++++D G+Y +L V + + +
Sbjct: 2570 -KEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPL 2626
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
D TV S++AVF+CEV++ G+W ++G + + I G +L+I + +D
Sbjct: 2627 TDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDI 2686
Query: 506 GDYTFVPDGYALSLSAKLNFLEIK 529
G+YT+ S K+ ++IK
Sbjct: 2687 GEYTYKVATSKTSAKLKVEAVKIK 2710
Score = 91.7 bits (226), Expect = 4e-18
Identities = 62/245 (25%), Positives = 116/245 (47%), Gaps = 7/245 (2%)
Query: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
+V G+ ++L V++S + W K+GQE++PS + + +L I T D Y
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2425
Query: 327 EVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVEL 385
+ T V V ++TPL+D V G + + +VS + V W + ++
Sbjct: 2426 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2485
Query: 386 TREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDI 445
+D +A + G + L+ + D G Y++I + L VE+ +++++ +
Sbjct: 2486 KPDDRVQAIVK----GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEK--IKIIRGL 2539
Query: 446 ADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDE 505
DLT ++ VF+ E+S + W E++PS + I G+ +KL + ++ +DE
Sbjct: 2540 RDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDE 2599
Query: 506 GDYTF 510
G YTF
Sbjct: 2600 GKYTF 2604
Score = 72.4 bits (176), Expect = 2e-12
Identities = 72/332 (21%), Positives = 135/332 (40%), Gaps = 32/332 (9%)
Query: 248 AKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENV 307
AK+ V+ + + QV + + E+++ D+ W+K+G EI + + V
Sbjct: 3138 AKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYV 3197
Query: 308 GKKRI--LTINKCTLADDAAYEVAVKDEKCFTELFVKEP-PVLIVTPLEDQQVFVGDRVE 364
++RI + I++ +D Y + L+V P P ++ L+ V G
Sbjct: 3198 VERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPAR 3257
Query: 365 MAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQED-------- 415
+S ++ W K+ E FK + F DG+ + L+ + ED
Sbjct: 3258 FCAVISGRPQPKISWYKE--EQLLSTGFKCK--FLHDGQEYTLLLIEAFPEDAAVYTCEA 3313
Query: 416 RGRYQVITNGGQCEAEL---IVEEKQLEV-----LQDIADLTVKASEQAVFKCEVSDEKV 467
+ Y V T E+ + ++++ V + + D + A F+C VS +
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL 3373
Query: 468 TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYA--------LSL 519
WY +++PS+ ++ ++L I + PEDEG YTFV LSL
Sbjct: 3374 KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Query: 520 SAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSE 551
A + L ++E + E ++ + + SE
Sbjct: 3434 EAPESILHERIEQEIEMEMKELFSEGESEHSE 3465
Score = 66.2 bits (160), Expect = 2e-10
Identities = 36/88 (40%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP-KFLITNYQGV 1102
F M P+F+ P+ D + A C+V G P P+V W K M I D K++I+ +G
Sbjct: 5376 FEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGS 5435
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEAL 1130
TL IR D+ TY CRAVN +GEA+
Sbjct: 5436 HTLKIRNVCLSDSATYRCRAVNCVGEAI 5463
Score = 65.9 bits (159), Expect = 2e-10
Identities = 242/1196 (20%), Positives = 419/1196 (35%), Gaps = 189/1196 (15%)
Query: 41 EDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKS 100
E+Q+ E F+ KP + G V +V G KP + W K G
Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP---KPHVYWKKS-----GVPL 1122
Query: 101 GARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDA 160
+ +K S+N + +L I D G Y + V+ K S ++ EA +
Sbjct: 1123 TTGYRYKVSYNKQTG--ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELL 1180
Query: 161 SGQSLESFKRTS-------EKKSDTAGELDFSGLLKKREVVEEE-KKKKKKDDDDLGIPP 212
E +T K +TA +S K+ E + +KK KD +
Sbjct: 1181 MKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYV 1240
Query: 213 EIWEL-LKGAKKSEYEKIAFQYGITDLRGMLKR--LKKAKVEVKKSAAFTKKLDPA---Y 266
E E + ++ ++I ++ T L +L+ +K V++ +S A D Y
Sbjct: 1241 EDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNY 1300
Query: 267 QVDRGNKIKLMVEISDPDLT-LKWFKNGQEIKPSSKYVFENVGKKRI-LTINKCTLADDA 324
++ G + ++S L + W+K+G+ IK +Y + + R L I D+
Sbjct: 1301 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360
Query: 325 AYEVAVKDEK----CFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMK 380
Y + K C +L+V EP + P + R+ S + +
Sbjct: 1361 IYTAFASNIKGNAICSGKLYV-EPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSP 1419
Query: 381 DGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLE 440
+ R + G+R ++E +E QLE
Sbjct: 1420 ARMSPARMSPARMSPARMSPGRR--------LEE-------------------TDESQLE 1452
Query: 441 VLQDIADLTVKASEQAVFKCEVS-----DEKVTGK------WYKNGVEVRP--SKRITIS 487
L V + FKC D KV G+ W+ +G ++ + ++ I
Sbjct: 1453 RLYK----PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIK 1508
Query: 488 HVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSG 547
G L+I P D G++T V A S + + VE V Q P
Sbjct: 1509 EDGT-QSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---LTVEAVEHQVKPMFVEKLKN 1564
Query: 548 KTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE-GRTRIEKRVDCSSFVIE 606
+ + G++L + V TG P P WLK ++ + + RIE ++ I+
Sbjct: 1565 ------VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1618
Query: 607 SAQREDEGRYTIKVTNPVGEDVASIFLQV-VDVPDP-PEAVRITSVGEDWAILVWEPPMY 664
S +D YT N G D + V V+ +P PE I G A + P +
Sbjct: 1619 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPEL- 1677
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
+P+ + G ++W EG LY+
Sbjct: 1678 ---EPL------HLRYGQEQWE------------------EGDLYDKEKQQKPFFKKKLT 1710
Query: 725 SMNTKPFMP------IAPTSEPLHLI--VEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYC 776
S+ K F P + P +P ++ + D + R N G +D Y V Y
Sbjct: 1711 SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD-YGVAYS 1769
Query: 777 LE------------GSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824
+ G++ E+ LP G + L R+ + E A
Sbjct: 1770 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH-EGAL 1828
Query: 825 LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS 884
+E +P + P +R GE G P+P+V W G + S
Sbjct: 1829 TGVTTDQKEKQKPDIVLYPEPVRVL----EGETARFRCRVTGYPQPKVNWYLNGQLIRKS 1884
Query: 885 R--------VH----VRTSDFDTVFFVRQAARSDSG--EYELSVQIENMKDTATIRIRV- 929
+ +H V +DT V+ A + G E+++ ++I+ +D ++ R
Sbjct: 1885 KRFRVRYDGIHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1943
Query: 930 -----------------VEKAGPPINVM----VKEVWGTNALVEWQAPKDDGNSEIMGYF 968
V+K P++ V ++ + + P++ + E+ F
Sbjct: 1944 EPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE--SEELRSKF 2001
Query: 969 VQKADKKTMEWFNVYE-RNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
++ ++ E E ++R + +L+ + +T+ + + K A
Sbjct: 2002 KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKEL-----TEEEKKALAEE 2056
Query: 1028 LKTGI-TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
K I TFKP + + APK + + V G A V G P P+ W KN +
Sbjct: 2057 GKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGV 2116
Query: 1087 EI-REDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+I R D + V L IR + D+ + +A+N GE + L V+ Q
Sbjct: 2117 KIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 65.5 bits (158), Expect = 3e-10
Identities = 33/94 (35%), Positives = 46/94 (48%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P ++ L + V+ G S L C + G+P P V W + +I F IT G+ L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
R D+G +TC AVNE G C L V+V +
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036
Score = 53.1 bits (126), Expect = 1e-06
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 1043 DFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGV 1102
D M P F+ PL R V + V G P P V W +NK + D + + V
Sbjct: 5178 DNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNV 5237
Query: 1103 LTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
+L I + G Y C AVN +GEA + +++ +PQ
Sbjct: 5238 CSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI-MPQ 5275
Score = 51.2 bits (121), Expect = 5e-06
Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P +TPL D V G A C V G KV W +I+ F +T ++ L I
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P D GTYT A N +G+ + L + P+
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3437
Score = 49.3 bits (116), Expect = 2e-05
Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 17/204 (8%)
Query: 443 QDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSKR--ITISHVGRFHKLVIDD 499
Q + + V A F+ +S V W+++G + S + IS KL I
Sbjct: 10 QPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPA 69
Query: 500 VRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 559
V + G Y+ + ++ L +K E P ++ ++ V G
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELL-VKAETAPPNFVQRLQ----------SMTVRQG 118
Query: 560 NKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618
+++RL V +TG P PV + + G E+ ++ + +I + D S +I A ED G Y++
Sbjct: 119 SQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD--FQISQEGDLYSLLIAEAYPEDSGTYSV 176
Query: 619 KVTNPVGEDVASIFLQVVDVPDPP 642
TN VG ++ L V + P
Sbjct: 177 NATNSVGRATSTAELLVQGEEEVP 200
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/128 (24%), Positives = 53/128 (41%)
Query: 1014 LSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRG 1073
LS S + + + + F +++ R P FL + + V G S C +G
Sbjct: 3910 LSASTRIDEFKTEQKEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQG 3969
Query: 1074 HPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAEC 1133
+P+P V W N M I + F+I + + L + + G+ TC N+ G
Sbjct: 3970 YPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTS 4029
Query: 1134 KLEVRVPQ 1141
L+V+ Q
Sbjct: 4030 MLKVKAKQ 4037
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Query: 351 PLEDQQVFVGDRVEMAVEVSEEGA-QVMWMKDGVELTREDSFKARYRFKKDGKRHILIFS 409
PL+ V G +S +V W +DG ++ + F DG+ + I +
Sbjct: 11 PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRAKLTIPA 69
Query: 410 DVVQEDRGRYQV-ITNG-GQCE--AELIVEEKQL--EVLQDIADLTVKASEQAVFKCEVS 463
V + + GRY + TNG GQ AEL+V+ + +Q + +TV+ Q + V+
Sbjct: 70 -VTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 464 DEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
K+Y++G E++ S IS G + L+I + PED G Y+
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/94 (30%), Positives = 40/94 (42%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P+ L L V +G A + G P+PK+ W K + + K + TL +
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
P DA YTC A N+ G A L V VP+
Sbjct: 3299 IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 44.3 bits (103), Expect = 7e-04
Identities = 28/91 (30%), Positives = 42/91 (46%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
P F+ L V G L V G P P V + ++ EI+ F I+ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
P D+GTY+ A N +G A + +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED--PKFLITNYQGVLT 1104
AP F PL VV+ G +A + G P P+V W ++ I P I+ G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L I + ++G Y+ +A N G+A + +L V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/170 (22%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 553 AIVVVAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSSFVIESAQRE 611
++VV+ G+ + I+G P P +W + G + T+T +I + I + +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 612 DEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVT 671
+ GRY++K TN G+ ++ L V PP V+ ++ V + VT
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ-----SMTVRQGSQVRLQVRVT 128
Query: 672 GY---LVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 718
G +V+ + G++ L+F++ E S + E + ++VNA
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNA 178
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/285 (21%), Positives = 104/285 (36%), Gaps = 41/285 (14%)
Query: 389 DSFKARYRFKKDGKRHILIFSDVVQEDR-----GRYQVITNGGQCEAELIVEEKQLEVLQ 443
D++K+ + + + I V+E+R GR +T + A + + ++
Sbjct: 888 DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVS 947
Query: 444 DIADLTVKASEQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRP 502
+ ++TV E +C +S T WY+ ++ S I+ +L+I +
Sbjct: 948 GLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFA 1007
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKV-EYVPKQ----------------EPPKIHLDC 545
ED G +T A ++S +L ++V E K+ E + +
Sbjct: 1008 EDSGRFTCSAVNEAGTVSTSC-YLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTD 1066
Query: 546 SGKTSENA--------------IV--VVAGNKLRLDVSITGEPPPVATWLKGDEVFTT-T 588
+ T E A +V +V G + + G P P W K TT
Sbjct: 1067 TSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGY 1126
Query: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
+ K+ VI +D G YTI V N GE AS L
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 42.4 bits (98), Expect = 0.003
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121
G S L C + G P+P V W +N + ++++ KF L I+ + D+G Y C
Sbjct: 4173 GDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCV 4232
Query: 1122 AVNELG--EALAECKLE 1136
A N G E++++ +E
Sbjct: 4233 AENNSGAVESVSDLTVE 4249
Score = 42.4 bits (98), Expect = 0.003
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 2/103 (1%)
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
+LK+ T FE++ + P+F+ + D G +A C VRG P+P V W K+
Sbjct: 5495 VLKSNYTDSFFEFQVVEG--PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGK 5552
Query: 1087 EIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129
++ + + G L I D G Y C A N+ G A
Sbjct: 5553 LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 5595
Score = 42.0 bits (97), Expect = 0.003
Identities = 82/398 (20%), Positives = 133/398 (33%), Gaps = 77/398 (19%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV----AVKDEKCFTELFV- 341
+KW++N ++P + E VG L I+ + Y + + K F + +
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Query: 342 --KEPPVLIVTPLEDQQVFVGD-------------RVEMAVEVSEEGAQVMWMKDGVELT 386
+E V + P+ Q V D + + VE+SE KD E
Sbjct: 5274 PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSE--------KDVKEFE 5325
Query: 387 REDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG---QCEAELIVEEKQLEVLQ 443
++ F D K +++ DV+ + + + G + + +L V E +
Sbjct: 5326 KQVKIVTVPEFTPDHK-SMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIM 5384
Query: 444 DIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRPSK-RITISHVGRFHKLVIDDVR 501
I D + + AVFKC V KWYK + + P + IS H L I +V
Sbjct: 5385 PICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVC 5444
Query: 502 PEDEGDY-------------------------TFVPDGYALSLSAKLNFLEIKVEYVPK- 535
D Y + ++LS+ + L +K Y
Sbjct: 5445 LSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSF 5504
Query: 536 ------QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTE 589
+ PP+ S G + G P P W K ++ +
Sbjct: 5505 FEFQVVEGPPRFIKGISD------CYAPIGTAAYFQCLVRGSPRPTVYWYKDGKL---VQ 5555
Query: 590 GR--TRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 625
GR T E + I S + DEG Y TN G
Sbjct: 5556 GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 5593
Score = 40.4 bits (93), Expect = 0.010
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGD-EVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
+ V+ G + L+ I+G P P TW + D ++ ++ + + + + + +I A ED
Sbjct: 952 VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI--ARLMIREAFAED 1009
Query: 613 EGRYTIKVTNPVGEDVASIFLQV 635
GR+T N G S +L V
Sbjct: 1010 SGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 38.1 bits (87), Expect = 0.048
Identities = 48/197 (24%), Positives = 83/197 (42%), Gaps = 29/197 (14%)
Query: 287 LKWFKNGQEIK----PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEK----CFTE 338
+ WF++GQ I P + F + K LTI T A+ Y + + E
Sbjct: 37 VSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTAE 94
Query: 339 LFVKEP--PVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM-WMKDGVELTREDSFKARY 395
L VK P V L+ V G +V + V V+ V+ + +DG E+ F+
Sbjct: 95 LLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQ--- 151
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQV-ITNG---GQCEAELIVEEKQLEVLQDIADLTVK 451
++G + L+ ++ ED G Y V TN AEL+V+ ++ ++ K
Sbjct: 152 -ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--------EVPAK 202
Query: 452 ASEQAVFKCEVSDEKVT 468
++ V ++S+ + T
Sbjct: 203 KTKTIVSTAQISESRQT 219
Score = 38.1 bits (87), Expect = 0.048
Identities = 36/150 (24%), Positives = 64/150 (42%), Gaps = 5/150 (3%)
Query: 559 GNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCS-SFVIESAQREDEGRYT 617
G+ + L+ I+GEP PV TW + + V + + E+ V+CS I+ +D G+Y
Sbjct: 4173 GDSIILECLISGEPQPVVTWFQ-NGVLLKQNQKFQFEE-VNCSHQLYIKDVNSQDSGKYK 4230
Query: 618 IKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 677
N G V S+ V+ E + ++GE + + + D G+ V + +
Sbjct: 4231 CVAENNSGA-VESVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQGESVRAHFYDY 4289
Query: 678 KKKGSQRWMKLNFEVFTETTYESTKMIEGI 707
W + E ++S + IE I
Sbjct: 4290 PAGPFTPWTNVK-EYSVRDYFQSLETIEQI 4318
Score = 37.0 bits (84), Expect = 0.11
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 451 KASEQAVFKCEVSDE-KVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
+ + + +C +S E + W++NGV ++ +++ V H+L I DV +D G Y
Sbjct: 4171 REGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYK 4230
Query: 510 FVPD 513
V +
Sbjct: 4231 CVAE 4234
Score = 36.2 bits (82), Expect = 0.18
Identities = 57/267 (21%), Positives = 99/267 (37%), Gaps = 40/267 (14%)
Query: 874 WTKGGAPLD-TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
W + G L T+ + + + D GEY + ++ K +A +++ V+
Sbjct: 2652 WLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVKI 2709
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCT 992
N+ V E VE P G I V ++++K + + + S
Sbjct: 2710 KKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEK----YAISVKGTIYSLR 2765
Query: 993 VSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLT 1052
+ + + +E VY + L S + T +I+K PK +T
Sbjct: 2766 IKNCAIVDE---SVYGFRLGRLGASARLHVETVKIIKK-----------------PKDVT 2805
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSP 1112
L + V S + H V W +EI+ K + + + V L ++ SP
Sbjct: 2806 ALENATVAFEVSVS-------HDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2858
Query: 1113 FDAGTYTCRAVNELGEALAECKLEVRV 1139
DAG YT V +L ECK ++ V
Sbjct: 2859 SDAGEYTA-VVGQL-----ECKAKLFV 2879
Score = 35.0 bits (79), Expect = 0.41
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITN----YQGVL 1103
P F L + V+ G C + P P++ W N I + +I +
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
+L I+R D+G+Y A+N G A + L V
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597
Score = 33.5 bits (75), Expect = 1.2
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 848 QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR---VHVRTSDFDTVFFVRQAAR 904
Q+ + G G P P+V W + G + TS V + SD + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 905 SDSGEYELSVQIENMKDTATIRIRVVEKAGPP 936
++SG Y L + + T+T + V + PP
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 458 FKCEVSDEKVTG-KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDY 508
F EV V G KWY+N + P +RI + VG L I +++ + G+Y
Sbjct: 5202 FIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEY 5253
Score = 32.7 bits (73), Expect = 2.0
Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 836 EPPKI--RLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPL-DTSRVHVRTSD 892
EPPK+ +P+H R + G+ + L G+P+P V W + G L + +
Sbjct: 4156 EPPKMLQEMPKHARC----REGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVN 4211
Query: 893 FDTVFFVRQAARSDSGEYE 911
+++ DSG+Y+
Sbjct: 4212 CSHQLYIKDVNSQDSGKYK 4230
Score = 32.3 bits (72), Expect = 2.6
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 873 VWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
VW K G + S RVH+ + + + D+G Y ++ + + + + V+
Sbjct: 2387 VWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2446
Query: 932 KAGPPINVMVKEVWGTNALVEWQAPKDDGNS 962
P +V V E GT A++E + D S
Sbjct: 2447 VITPLKDVNVIE--GTKAVLECKVSVPDVTS 2475
Score = 32.0 bits (71), Expect = 3.4
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Query: 271 GNKIKLMVEIS-DPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVA 329
G+ I L IS +P + WF+NG +K + K+ FE V L I D Y+
Sbjct: 4173 GDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCV 4232
Query: 330 VKDEKCFTELFVKEPPVLIVTPLEDQQ 356
++ E V + V VT E+ Q
Sbjct: 4233 AENNSGAVE-SVSDLTVEPVTYRENSQ 4258
Score = 31.6 bits (70), Expect = 4.5
Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 6/122 (4%)
Query: 1009 ENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPK-----FLTPLIDRVVVAGY 1063
+N+C L ++++A I+ I E H F + F L D V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAG-ETSSHAFLLVQAKQLITFTQELQDVVAKEKD 2189
Query: 1064 SAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAV 1123
+ A P KV W K+ ME+ E K+ + + + V L+I DA Y+C V
Sbjct: 2190 TMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 1124 NE 1125
+
Sbjct: 2250 ED 2251
>gi|155969693 myomesin family, member 3 [Homo sapiens]
Length = 1437
Score = 112 bits (279), Expect = 3e-24
Identities = 114/469 (24%), Positives = 187/469 (39%), Gaps = 65/469 (13%)
Query: 601 SSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV-------PDPPEAVRITSVGED 653
+S + +EDEG Y ++V +P G S ++ V D P P VR V D
Sbjct: 328 ASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRD 387
Query: 654 WAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRV 713
IL W PP G P+T Y +ER + S W+ + ++EG Y RV
Sbjct: 388 CLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCPIQGLVEGQSYRFRV 447
Query: 714 FAVNAIGVSQPSMNTK----------------PF--------------MPIAPTSEPLHL 743
A++ +G S PS ++ PF + S P ++
Sbjct: 448 RAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTNV 507
Query: 744 IVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLP 802
++ + L W P+ + Y +E + GS W ++E PV F V +L
Sbjct: 508 HASEIREAYVVLAWEEPSPRDRAPLT-YSLEKSVIGSGTWEAISSESPVRSPRFAVLDLE 566
Query: 803 TGARILFRVVGVNIAGRSEPATLAQPVTIR----EIAEPPKIRLPRHLRQTYIR------ 852
+FRV +N G S+P+ ++P+ +R + P +++ R QT +
Sbjct: 567 KKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD-TQTSVSLTWDPV 625
Query: 853 KVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHV---RTSDFDTVFFVRQAARSDSGE 909
K E L + + K T P+ +R V RT + F VR + + GE
Sbjct: 626 KDPELLGYYI-YSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGK-EYEFCVRSVSEAGVGE 683
Query: 910 YELSVQIENMKDTATIRIR-VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYF 968
+ T IR++ + P + ++ W+ PK G +I+GYF
Sbjct: 684 SSAA--------TEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYF 735
Query: 969 VQKADKKTMEWFNVYERNRHTS-CTVSDLIVGNEYYFRVYTENICGLSD 1016
+ + D + ++W V ++ T C VSDL G+ Y FR N G+ +
Sbjct: 736 LDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGE 784
Score = 108 bits (271), Expect = 2e-23
Identities = 86/376 (22%), Positives = 154/376 (40%), Gaps = 27/376 (7%)
Query: 556 VVAGNKLRLDVSITGEP---PPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612
V A + VS+T +P P + + T+E +T K + + F + +
Sbjct: 608 VQAFRDTQTSVSLTWDPVKDPELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGK 667
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDV------PDPPEAVRITSVGEDWAILVWEPPMYDG 666
E + ++ + G +S + + V P P + + G++ ++ W+PP G
Sbjct: 668 EYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRG 727
Query: 667 GKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSM 726
G + GY +++ W +N + + + + EG YE R A N GV + S
Sbjct: 728 GGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSA 787
Query: 727 NTKPF----MPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEE 782
+ F + P + +V T+ L+W PP +GAG + GY V + EGSE+
Sbjct: 788 PSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQ 847
Query: 783 WVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRL 842
W P P+ V +L G +F+V +N AG +P+ PV + + +I +
Sbjct: 848 WKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEV 907
Query: 843 PRHLRQTYIRKVGEQLNLVVPFQGKPRP---QVVWTKG-GAPLDTSRVHVRTSDFDTVFF 898
V E+ + + F+ P + W+K PLD RV + +
Sbjct: 908 ----------GVDEEGFIYLAFEAPEAPDSSEFQWSKDYKGPLDPQRVKIEDKVNKSKVI 957
Query: 899 VRQAARSDSGEYELSV 914
+++ D G Y + V
Sbjct: 958 LKEPGLEDLGTYSVIV 973
Score = 102 bits (255), Expect = 2e-21
Identities = 144/653 (22%), Positives = 233/653 (35%), Gaps = 85/653 (13%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYALSLSAKLNFLEI 528
+W+++G +R S+R I + R L + EDEG Y VP + + +
Sbjct: 305 QWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRD 364
Query: 529 KVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITG-----------------E 571
P +++ C + I+ A IT E
Sbjct: 365 AEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHE 424
Query: 572 PP------PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 625
P P+ ++G +R+ V + + D R ++ +G
Sbjct: 425 APGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLG 484
Query: 626 EDVA---SIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGS 682
+ F V +P PP V + + E + +L WE P P+T Y +E+ GS
Sbjct: 485 NKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLT-YSLEKSVIGS 543
Query: 683 QRWMKLNFEV------FTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM---P 733
W ++ E F E K Y RV A+N G+S PS ++P P
Sbjct: 544 GTWEAISSESPVRSPRFAVLDLEKKKS-----YVFRVRAMNQYGLSDPSEPSEPIALRGP 598
Query: 734 IAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVER 793
A P + T T+ +L W P + + GY + G+ EW N +P++
Sbjct: 599 PATLPPPAQVQAFRDTQTSVSLTWDP---VKDPELLGYYIYSRKVGTSEWQTVNNKPIQG 655
Query: 794 CGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRK 853
FTV L TG F V V+ AG E + +P+ +++ P P K
Sbjct: 656 TRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSA--PYGFALLNCGK 713
Query: 854 VGEQLNLVVPFQ---GKPRPQVVWTKGGAPLDTSRVH--------VRTSDFDTVFFVRQA 902
+ P + GK + LD V+ + SD F
Sbjct: 714 NEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFR 773
Query: 903 ARSDS----GEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKD 958
AR+ + GE + K+ + + GPP +V EV T+ +++W+ P
Sbjct: 774 ARAANWAGVGELSAPSSLFECKEWT------MPQPGPPYDVRASEVRATSLVLQWEPPLY 827
Query: 959 DGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFRVYTENICG---- 1013
G + GY V ++ + +W V T VSDL G Y F+V N G
Sbjct: 828 MGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQP 887
Query: 1014 --------LSDSPGVSKNTARILKTGITFKPFEYKE----HDFRMAPKFLTPL 1054
L D PG + + + G + FE E +F+ + + PL
Sbjct: 888 SMPTDPVLLEDKPGAHEIEVGVDEEGFIYLAFEAPEAPDSSEFQWSKDYKGPL 940
Score = 60.8 bits (146), Expect = 7e-09
Identities = 40/107 (37%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 1038 EYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDP----- 1092
E +E + P F PL V + L C V+ P P+V W KN + R DP
Sbjct: 144 ELRELCYGRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKN--DTRIDPRLFRA 201
Query: 1093 -KFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
K+ ITN G+L+L IRR + D+ TYT R N G+A + K+ VR
Sbjct: 202 GKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVR 248
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 556 VVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGR 615
++ L L ++G+P P +WLK D+ T + R R+E R + IE ED GR
Sbjct: 1346 IMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLD-RYRMEVRGTEVTITIEKVNSEDSGR 1404
Query: 616 YTIKVTNPVGEDVASIFLQVVDVPDPPEAVR 646
Y + V N G + + + V D P+ ++
Sbjct: 1405 YGVFVKNKYGSETGQVTISVFKHGDEPKELK 1435
Score = 42.4 bits (98), Expect = 0.003
Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 9/144 (6%)
Query: 872 VVWTKGGAPLDTSRVH-VRTSDFDTVFFVRQAARSDSGEYELSVQ--IENMKDTATIRIR 928
+ W + G+ L +SR + +D V + D G Y + V + + + +R
Sbjct: 304 IQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVR 363
Query: 929 VVEKAGP-----PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVY 983
E P P+NV +V ++ W P D + I Y +++ ++ EW +
Sbjct: 364 DAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACH 423
Query: 984 ERNRHT-SCTVSDLIVGNEYYFRV 1006
E T C + L+ G Y FRV
Sbjct: 424 EAPGGTCRCPIQGLVEGQSYRFRV 447
Score = 36.2 bits (82), Expect = 0.18
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 564 LDVSITGEPPPVATWLKGD---EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
L ++ PPP TW K D + G+ RI S I ED YT++V
Sbjct: 173 LTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRV 232
Query: 621 TNPVGEDVASIFLQVV 636
N G+ AS F +V+
Sbjct: 233 KNAHGQ--ASSFAKVL 246
Score = 36.2 bits (82), Expect = 0.18
Identities = 35/138 (25%), Positives = 51/138 (36%), Gaps = 17/138 (12%)
Query: 213 EIWELLKGAKKSEYEKIAFQYGI--------TDLRGML--------KRLKKAKVEVKKSA 256
EIW + K S+ K + TDL G +RLK + K A
Sbjct: 1275 EIWLHILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRA 1334
Query: 257 AFTKKLDPAYQVDRGNKIKLMVEIS-DPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTI 315
+ L + + L +S DP + W KN Q + +Y E G + +TI
Sbjct: 1335 KVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITI 1394
Query: 316 NKCTLADDAAYEVAVKDE 333
K D Y V VK++
Sbjct: 1395 EKVNSEDSGRYGVFVKNK 1412
Score = 35.8 bits (81), Expect = 0.24
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 810 RVVGVNIAGRSEPATLAQPVTIREIA--EPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGK 867
R + +++G++ +A+ ++ +A E + ++ R L + L L G
Sbjct: 1302 RQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGD 1361
Query: 868 PRPQVVWTKGGAP---LDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTAT 924
P P++ W K P LD R+ VR + + + + DSG Y + V+ + +T
Sbjct: 1362 PTPEISWLKNDQPVTFLDRYRMEVRGT--EVTITIEKVNSEDSGRYGVFVKNKYGSETGQ 1419
Query: 925 IRIRVVEKAGPP 936
+ I V + P
Sbjct: 1420 VTISVFKHGDEP 1431
Score = 35.0 bits (79), Expect = 0.41
Identities = 17/71 (23%), Positives = 32/71 (45%)
Query: 1067 LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNEL 1126
L C V G P P++ W+KN + ++ + +T+ I + + D+G Y N+
Sbjct: 1354 LTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKY 1413
Query: 1127 GEALAECKLEV 1137
G + + V
Sbjct: 1414 GSETGQVTISV 1424
Score = 32.7 bits (73), Expect = 2.0
Identities = 41/174 (23%), Positives = 59/174 (33%), Gaps = 40/174 (22%)
Query: 281 SDPDLTLKWFKNGQEIKP----SSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCF 336
+ P + W+KN I P + KY N L I +C + D A Y V VK+
Sbjct: 179 ASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQ 238
Query: 337 TELFVKEPPVLIVTPLE-----DQQVFVGDRVEMAVEVSE-------------------- 371
F K VL+ T L D ++F +VE +
Sbjct: 239 ASSFAK---VLVRTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKEPFSLSCLFS 295
Query: 372 ----EGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQV 421
+ + W +DG L K Y ++ L S +ED G Y V
Sbjct: 296 EDVLDAESIQWFRDGSLLRSSRRRKILY----TDRQASLKVSCTYKEDEGLYMV 345
Score = 32.0 bits (71), Expect = 3.4
Identities = 38/186 (20%), Positives = 74/186 (39%), Gaps = 21/186 (11%)
Query: 241 MLKRLKKAKVEVKKSAAF--TKKLDPAYQVDRGNKI-KLMVEISDPDLTLKWFKNGQEIK 297
+ ++K VE K+ F K+L+ ++ G + ++ + I DP + K
Sbjct: 1238 IFSKVKYYNVEYMKTTWFHKDKRLESGDRIRTGTTLDEIWLHILDPKDSDK--------- 1288
Query: 298 PSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQV 357
KY E K + ++ L+ A + + ++ T +++ +V L D
Sbjct: 1289 --GKYTLEIAAGKEVRQLST-DLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVAT 1345
Query: 358 FVGDRVEM--AVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQED 415
+ D+ + + ++ W+K+ +T F RYR + G + V ED
Sbjct: 1346 IMEDKTLCLTCIVSGDPTPEISWLKNDQPVT----FLDRYRMEVRGTEVTITIEKVNSED 1401
Query: 416 RGRYQV 421
GRY V
Sbjct: 1402 SGRYGV 1407
>gi|140560919 myomesin 1 isoform a [Homo sapiens]
Length = 1685
Score = 110 bits (275), Expect = 8e-24
Identities = 78/268 (29%), Positives = 116/268 (43%), Gaps = 39/268 (14%)
Query: 610 REDEGRYTIKVTNPVGEDVASIFLQVVDV-------PDPPEAVRITSVGEDWAILVWEPP 662
+EDEG YTI+V + S ++ V D P P V+ +D+ I+ W+ P
Sbjct: 474 KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
Query: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
DGG P+ GY +++ + G+ W + N + T +IEG Y RV AVN +G+
Sbjct: 534 AVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIG 593
Query: 723 QPSMNTKPFMPIAPTSE------------------------------PLHLIVEDVTDTT 752
PS ++P + P + P L V + T +
Sbjct: 594 FPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSY 653
Query: 753 TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLPTGARILFRV 811
L W+PP + G GI Y VE C G+E W NTE PV+ F + +L G FRV
Sbjct: 654 VVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRV 712
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPK 839
N AG EP+ + + + + PK
Sbjct: 713 RCSNSAGVGEPSEATEVTVVGDKLDIPK 740
Score = 99.0 bits (245), Expect = 2e-20
Identities = 140/621 (22%), Positives = 233/621 (37%), Gaps = 103/621 (16%)
Query: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDG-YALSLSAKLNFLE 527
+WY+NGV + PSK + G L + EDEG YT V G Y SA + +
Sbjct: 442 QWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRD 501
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
E + P LD + ++++ + +D G P + ++ EV T
Sbjct: 502 ADAEI---EGAPAAPLDVKCLEANKDYIIISWKQPAVD----GGSPILGYFIDKCEVGTD 554
Query: 588 T--------------------EGRTRI-------EKRVDCSSFVIESAQREDEGRYTIKV 620
+ EGR+ I + + S V E D
Sbjct: 555 SWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLK 614
Query: 621 TNPVGEDVASIFLQVVD-----VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
+ P I + + VP PP + +T + +L W+PP G + + Y V
Sbjct: 615 SRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFV 673
Query: 676 ERKKKGSQRWMKLNFEVFTETT-YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-- 732
E+ + G++ W ++N E+ ++ + + EG Y RV N+ GV +PS T+ +
Sbjct: 674 EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
Query: 733 -PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791
+ P +I TDT+ + W A + GY +E + GS +W P N PV
Sbjct: 734 DKLDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKELVGYYIEASVAGSGKWEPCNNNPV 791
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851
+ FT L TG +FRV VN AG SE + ++ + ++
Sbjct: 792 KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVK------------------- 832
Query: 852 RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR---TSDFDTVFFVRQAARSDSG 908
+G ++ V P + GG RVH T D + + S
Sbjct: 833 AAIGGGVSPDV------CPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPS 886
Query: 909 EYELSVQIENMKDTATIRIRVV---EKAGP--------------------PINVMVKEVW 945
+ Q E K + T++ + +KA P P ++ E +
Sbjct: 887 SSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESF 946
Query: 946 GTNALVEWQAPKDDGNSEIMGYFV---QKADKKTMEWFNV-YERNRHTSCTVSDLIVGNE 1001
+ ++ W+ P G +EI GY+V + D +W + + +S+L
Sbjct: 947 RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMV 1006
Query: 1002 YYFRVYTENICGLSDSPGVSK 1022
Y F+V N+ GL VS+
Sbjct: 1007 YQFQVAAMNMAGLGAPSAVSE 1027
Score = 95.9 bits (237), Expect = 2e-19
Identities = 120/531 (22%), Positives = 206/531 (38%), Gaps = 55/531 (10%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQ---RWMKLNFEVFTE 695
P PP + D +L W+ P GG +TGY V ++ +W + N + +E
Sbjct: 934 PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPF----MPIAPTSEPLHLIVEDVTDT 751
Y+ + + E ++Y+ +V A+N G+ PS ++ F IA P L +V
Sbjct: 994 EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
Query: 752 TTTLKWRPPNRIGAGGIDGYLVEY--CLEGSEEWVPANTEPVERCGFTVKNLPTGARILF 809
+ L+W+PP G + GY V+ ++W N ++ V+ L G +F
Sbjct: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
Query: 810 RVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ---G 866
RV +N AG +P+ LA PV +AE R + + V + + + F+
Sbjct: 1114 RVRAINQAGVGKPSDLAGPV----VAE------TRPGTKEVVVNVDDDGVISLNFECDKM 1163
Query: 867 KPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSV----------- 914
P+ + W+K D+ R+ V + T + D G Y V
Sbjct: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
Query: 915 -QIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEW-QAPKDDGNSEIMGYFVQKA 972
E +K + P + + E+ + W QA K GN+++ F +K
Sbjct: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
Query: 973 DKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGI 1032
+ ++ +RN + + + E G + N + ++ G
Sbjct: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDED-------EGTYTFQLQDGKATNHSTVVLVGD 1336
Query: 1033 TFKPFEYKEHDF-------RMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK-PKVVWMKN 1084
FK + KE +F + P F+ + V + L C V K +VW K+
Sbjct: 1337 VFKKLQ-KEAEFQRQEWIRKQGPHFV-EYLSWEVTGECNVLLKCKVANIKKETHIVWYKD 1394
Query: 1085 KMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135
+ EI D K + G+ TL I S DAG Y ++ G+ + KL
Sbjct: 1395 EREISVDEKHDFKD--GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
Score = 67.0 bits (162), Expect = 1e-10
Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 4/117 (3%)
Query: 636 VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERK--KKGSQRWMKLNFEVF 693
+ VP PP +++ + V +D +L W+PP++ G PVTGY V+ K K +W LN
Sbjct: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
Query: 694 TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTD 750
+ + EG+ Y RV A+N GV +PS P +A T +V +V D
Sbjct: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV--VAETRPGTKEVVVNVDD 1150
Score = 60.5 bits (145), Expect = 9e-09
Identities = 74/303 (24%), Positives = 130/303 (42%), Gaps = 44/303 (14%)
Query: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNG--GQCEAELI 433
++W KD RE S ++ FK DG +LI ++ ++D G Y+VI G+ ++ L
Sbjct: 1389 IVWYKD----EREISVDEKHDFK-DGICTLLI-TEFSKKDAGIYEVILKDDRGKDKSRLK 1442
Query: 434 V-----EEKQLEVLQDIA----DLTVKASEQAV-----FKCEVSDEKVTGKWYKNGVEVR 479
+ +E +EV + IA DL ++++ + + V D KV W NG +R
Sbjct: 1443 LVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVN--WSHNGSAIR 1500
Query: 480 PSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYA-----LSLS------AKLNFLE 527
S R+ G L I++ P D+G Y + DG + LS A F
Sbjct: 1501 YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR 1560
Query: 528 IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587
+K + ++ ++ G + + + G L L ++ G+PPP +WLK ++ +
Sbjct: 1561 LKQAAIAEKNRARV---LGGLP--DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAS 1615
Query: 588 TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647
+ + + F I D G+Y + V N G + + V V P E R+
Sbjct: 1616 DDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDF---TVSVFIPEEEARM 1672
Query: 648 TSV 650
++
Sbjct: 1673 AAL 1675
Score = 55.8 bits (133), Expect = 2e-07
Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 9/168 (5%)
Query: 869 RPQVVWTKGGAPLDTSR-VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRI 927
+P++ W + G PL S+ V S + D G Y + V++ + + +
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
Query: 928 RV------VEKA-GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF 980
V +E A P++V E ++ W+ P DG S I+GYF+ K + T W
Sbjct: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
Query: 981 NVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
+ + V+ LI G Y FRV N G+ VS+ A +
Sbjct: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
Score = 49.7 bits (117), Expect = 2e-05
Identities = 88/415 (21%), Positives = 157/415 (37%), Gaps = 59/415 (14%)
Query: 735 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY--CLEG-SEEWVPANTEPV 791
AP S P + + + L W+ P++IG I GY V Y ++G +W AN + V
Sbjct: 932 APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAV 991
Query: 792 ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE--IAEPPKIRLPRHLRQT 849
+ + NL F+V +N+AG P+ +++ E IA P P L+ +
Sbjct: 992 SEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGP---PHSLKCS 1048
Query: 850 YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE 909
+RK L P P G +D + + +++
Sbjct: 1049 EVRKDSLVLQWKPPVHSGRTPVT-----GYFVDLKEAKAKEDQW--------RGLNEAAI 1095
Query: 910 YELSVQIENMKD--TATIRIRVVEKA--GPPIN----VMVKEVWGTNALVEWQAPKDDGN 961
+ +++ +K+ + R+R + +A G P + V+ + GT +V DDG
Sbjct: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVV--VNVDDDGV 1153
Query: 962 SEIMGYFVQKADKKTMEW------------FNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009
+ + K W V + T T DL + + +Y+
Sbjct: 1154 ISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDD---LGIYS- 1209
Query: 1010 NICGLSDSPGVSKN---TARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAA 1066
C ++D+ G++ + LK + EH F P + L ++ G
Sbjct: 1210 --CDVTDTDGIASSYLIDEEELKRLLALS----HEHKFPTVP-VKSELAVEILEKGQVRF 1262
Query: 1067 LNCAVRGHPKPKVVWMKNKMEIREDPKFL--ITNYQGVLTLNIRRPSPFDAGTYT 1119
A + KV ++ N+ EI E PK+ I G++ + + + D GTYT
Sbjct: 1263 WMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
Score = 46.2 bits (108), Expect = 2e-04
Identities = 139/679 (20%), Positives = 242/679 (35%), Gaps = 110/679 (16%)
Query: 12 PKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFL--KKPDSVSVETGKDA 69
P K AP+G K P K+ AP +PP D + + L K+PD +
Sbjct: 910 PPQKAAPQGKSKSDPLKKKTDRAPP-SPPCDITCLESFRDSMVLGWKQPDKIGG------ 962
Query: 70 VVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLG 129
A++ G + + I GKW E K+ + ++K S+ + VY + + + +
Sbjct: 963 ---AEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY--QFQVAAMNMA 1017
Query: 130 DRGYYRLEVKAKDTCDSCG-FNIDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSGLL 188
G A C C + I V P + + K SG
Sbjct: 1018 GLG----APSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV-----HSGRT 1068
Query: 189 KKREVVEEEKKKKKKDDDDLGIPP----EIWELLKGAKKSEYEKIAFQYGITDLRGMLKR 244
+ K+ K K+D G+ ++ ++G K E F+ + G+ K
Sbjct: 1069 PVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLK--EGVSYVFRVRAINQAGVGKP 1126
Query: 245 LKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISD--PDLTLKWFKNGQEIKPSSKY 302
A V ++ TK++ VD I L E P W K+ + S +
Sbjct: 1127 SDLAGPVVAETRPGTKEV--VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRL 1184
Query: 303 VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFV---KEPPVLIVTPLEDQQVFV 359
E+ G K +T + D Y V D ++ +E L+ E + V
Sbjct: 1185 EVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTV 1244
Query: 360 GDRVEMAVEVSEEGAQVMWM---------KDGVELTREDSFKA-RYRFKKDGKRHIL-IF 408
+ E+AVE+ E+G WM K ++ F+ +Y+ D I+ +F
Sbjct: 1245 PVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMF 1304
Query: 409 SDVVQ-EDRGRYQVITNGG------------------QCEAELIVEE---KQLEVLQDIA 446
+ +Q ED G Y G Q EAE +E KQ +
Sbjct: 1305 MEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYL 1364
Query: 447 DLTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKR---------ITISHVGR---- 491
V + KC+V++ K WYK+ E+ ++ + I+ +
Sbjct: 1365 SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAG 1424
Query: 492 FHKLVIDDVRPEDEGDYTFVPDGY-----ALSLSAKLNFLEIKVE--------------Y 532
+++++ D R +D+ V + + + L+ ++K++ Y
Sbjct: 1425 IYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYY 1484
Query: 533 VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592
V + H + + S+ V G ++ L ++ EP P KG V +G+T
Sbjct: 1485 VEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN---EPTPND---KGKYVMELFDGKT 1538
Query: 593 RIEKRVDCSSFVIESAQRE 611
+K VD S + A E
Sbjct: 1539 GHQKTVDLSGQAYDEAYAE 1557
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR---EDPKFLITNYQGVL 1103
AP+F+ V + L+C++ G P+P+V W KN++ I K++I + G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
TL I D Y A+N GE A + V+
Sbjct: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 38.1 bits (87), Expect = 0.048
Identities = 48/217 (22%), Positives = 79/217 (36%), Gaps = 53/217 (24%)
Query: 274 IKLMVEISD-PDLTLKWFKNGQEIKPSS---KYVFENVGKKRILTINKCTLADDAAYEVA 329
+KL I+ P+ + W+KN I + KY+ E+ L IN C D A Y +
Sbjct: 294 VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
Query: 330 VKDEK----CFTELFVKE-----------------PPVLIVTPL---------------- 352
+ K + + VK P VTP
Sbjct: 354 AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
Query: 353 ----EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIF 408
E + + +G RV + E+ ++ W ++GV L+ + + G+R L F
Sbjct: 414 SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLW----SGERATLTF 469
Query: 409 SDVVQEDRGRYQVITNGG----QCEAELIVEEKQLEV 441
S + +ED G Y + G Q A + V + E+
Sbjct: 470 SHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI 506
Score = 37.7 bits (86), Expect = 0.063
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 58 PDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVY 117
PD V+++ GK + V G P+ + W K + L S F+
Sbjct: 1579 PDVVTIQEGKALNLTCNVWGDPPPE---VSWLKNE-KALASDDHCNLKFEAGR------- 1627
Query: 118 TVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKK 175
T I V D G Y L VK K ++ F + V P ++A +LES K + K
Sbjct: 1628 TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK 1685
Score = 35.8 bits (81), Expect = 0.24
Identities = 37/181 (20%), Positives = 75/181 (41%), Gaps = 10/181 (5%)
Query: 458 FKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYA 516
F+C+ K W K+ V S R+ + G K+ D+ +D G Y+ V D
Sbjct: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
Query: 517 LSLSAKLNFLEIK--VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLR--LDVSITGEP 572
++ S ++ E+K + + + P + + SE A+ ++ ++R +
Sbjct: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPV-----KSELAVEILEKGQVRFWMQAEKLSGN 1272
Query: 573 PPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF 632
V E+F + + I++ +E Q EDEG YT ++ + + +++
Sbjct: 1273 AKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVV 1332
Query: 633 L 633
L
Sbjct: 1333 L 1333
Score = 35.4 bits (80), Expect = 0.31
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Query: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQG-VLTLNIRRPSPFDAGTYTC 1120
G + L C V G P P+V W+KN+ + D + G I S D+G Y
Sbjct: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
Query: 1121 RAVNELGEALAECKLEVRVPQ 1141
N+ G ++ + V +P+
Sbjct: 1647 VVKNKYGSETSDFTVSVFIPE 1667
Score = 34.7 bits (78), Expect = 0.53
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 814 VNIAGRSEPATLAQPVTIRE--IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
V+++G++ A+ +++ IAE + R+ L + G+ LNL G P P+
Sbjct: 1544 VDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPE 1603
Query: 872 VVWTKGGAPL-DTSRVHVRTSDFDTVFF-VRQAARSDSGEYELSVQIENMKDTATIRIRV 929
V W K L +++ T +F + + +DSG+Y L V+ + +T+ + V
Sbjct: 1604 VSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/67 (29%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 562 LRLDVSITGEPPPVATWLKGDEVFT--TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619
++L SI G P P TW K G+ IE R + I ED +Y
Sbjct: 294 VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
Query: 620 VTNPVGE 626
N GE
Sbjct: 354 AMNVKGE 360
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 102 bits (255), Expect = 2e-21
Identities = 130/499 (26%), Positives = 192/499 (38%), Gaps = 76/499 (15%)
Query: 283 PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV------KDEKCF 336
P+ T+ W K+G + + + GK I K DA V V + E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 337 TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKARY 395
EL V E P + P + V V D E E + V W KD EL K+RY
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP-----KSRY 268
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNG----GQCEAELIVEEKQLEVLQDIADLTVK 451
+ D H L V D G Y + + A L V+E V++ D V
Sbjct: 269 EIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKP-RDQVVA 324
Query: 452 ASEQAVFKCEVSDEKVTGK-WYKNGVE--------VRPSKRITISHVGRFHKLVIDDVRP 502
F+CE + W + G + + S R ++S G L I +V+
Sbjct: 325 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQR 381
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKL 562
D G Y A S+ K +LE+ + + + PP I + N V V G +
Sbjct: 382 SDVGYYICQTLNVAGSIITKA-YLEV-TDVIADRPPPVIR-----QGPVNQTVAVDGTFV 434
Query: 563 RLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN 622
L TG P P W K + +T + R K+++ I A+ D GRYT +
Sbjct: 435 -LSCVATGSPVPTILWRKDGVLVSTQDSRI---KQLENGVLQIRYAKLGDTGRYTCIAST 490
Query: 623 PVGEDVASIFLQVVD---------------VPDPPEAVRITSVGEDWAILVWEPPMYDGG 667
P GE S +++V + +P P +T V + L W+P + G
Sbjct: 491 PSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGA 550
Query: 668 KPVTGYLVERKKKGS-QRWMKLNFEVFTETTYESTKMIEGI----LYEMRVFAVNAIGVS 722
P T Y++E S W + V TET+ I+G+ +Y V A NA G+S
Sbjct: 551 TP-TSYIIEAFSHASGSSWQTVAENVKTETS-----AIKGLKPNAIYLFLVRAANAYGIS 604
Query: 723 QPSMNTKPF--MPIAPTSE 739
PS + P + PTS+
Sbjct: 605 DPSQISDPVKTQDVLPTSQ 623
Score = 82.8 bits (203), Expect = 2e-15
Identities = 141/607 (23%), Positives = 214/607 (35%), Gaps = 99/607 (16%)
Query: 283 PDLTLKWFKNGQEIK-----PSSKYVFENVGKKRILTI--NKCTLADDAAYEVAVKDEKC 335
P T++W+K G+ ++ P S + G L I + + D+ Y ++
Sbjct: 56 PTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN--- 112
Query: 336 FTELFVKEPPVLIVTPLEDQ--------QVFVGDRVEMAVEVSEEGAQ--VMWMKDGVEL 385
+ V L V L D V VG+ M + + + W KDG L
Sbjct: 113 YLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL 172
Query: 386 TREDS--------FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
+D Y K D +++ + +++V E AEL V E+
Sbjct: 173 DDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEV----------AELTVLER 222
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLV 496
V + ++L V + A FKCE + V T +W K+ E+ P R I H L
Sbjct: 223 PSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDD---HTLK 277
Query: 497 IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVV 556
I V D G YT V + A + QEPP + + VV
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASAT--------LTVQEPPHFVVKPRDQ------VV 323
Query: 557 VAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSS---FVIESAQRED 612
G + TG P P W + G + + + R S I + QR D
Sbjct: 324 ALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSD 383
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDV--PDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
G Y + N G + +L+V DV PP +R V + A+ G V
Sbjct: 384 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAV---------DGTFV 434
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG-----VSQPS 725
+ + W K V T+ + K +E + ++R + G S PS
Sbjct: 435 LSCVATGSPVPTILWRKDGVLVSTQDS--RIKQLENGVLQIRYAKLGDTGRYTCIASTPS 492
Query: 726 MNTK------------PFMPIAPT------SEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P PT S P V DV+ T TL W+P GA
Sbjct: 493 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 552
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y++E S E V+ +K L A LF V N G S+P+ ++
Sbjct: 553 TS-YIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 611
Query: 828 PVTIREI 834
PV +++
Sbjct: 612 PVKTQDV 618
Score = 63.5 bits (153), Expect = 1e-09
Identities = 133/619 (21%), Positives = 213/619 (34%), Gaps = 77/619 (12%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR-------F 492
+++ +DL V E A C+ T +WYK G V K SH F
Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF 90
Query: 493 HKLVIDDVRPEDEGDYTFVPDGY---ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
++V DEG Y V Y A+S +A L ++ ++ +Q P
Sbjct: 91 LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF--RQNP----------- 137
Query: 550 SENAIVVVAGNKLRLDVSIT-GEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
+ ++V G ++ G P P +W K + R I +I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMITYT 191
Query: 609 QREDEGRYTIKVTNPVGEDVASIF-LQVVDVPD---PPEAVRITSVGEDWAILVWEPPMY 664
++ D G+Y TN VGE + + L V++ P P + +T +D A E
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEAR-- 247
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
G PV R +K K +E+ + T + K+ G + A N +G ++
Sbjct: 248 --GDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEA 302
Query: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
S EP H +V+ D L + A G + + EGS+ +
Sbjct: 303 SATLT-------VQEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 354
Query: 785 PANTEPVERCGFTVKNLPTGARILFRV----VGVNIAGRSEPATLAQPVTIREIAEPPKI 840
+ P F+V TG + V VG I A E+ +
Sbjct: 355 FSYQPPQSSSRFSVSQ--TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD 412
Query: 841 RLPRHLRQTYIRK---VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
R P +RQ + + V L G P P ++W K G + T ++ + + V
Sbjct: 413 RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVL 471
Query: 898 FVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP---------------PINVMVK 942
+R A D+G Y + + T + I V E P P V
Sbjct: 472 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVT 531
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
+V + WQ + G + + W V E + + + L Y
Sbjct: 532 DVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIY 591
Query: 1003 YFRVYTENICGLSDSPGVS 1021
F V N G+SD +S
Sbjct: 592 LFLVRAANAYGISDPSQIS 610
Score = 57.4 bits (137), Expect = 8e-08
Identities = 77/326 (23%), Positives = 128/326 (39%), Gaps = 52/326 (15%)
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS----RV 886
+R+ PP R+ H + K GE L +G+P P + W KGG ++T R
Sbjct: 22 LRQEDFPP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 887 HVRTSDFDTVFFVR----QAARSDSGEYELSVQI---ENMKDTATIRIRVVEK--AGPPI 937
H ++FF+R + +R D G Y + E + A++ + ++ P
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPS 138
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI 997
+VMV G A++E Q P+ I K D ++ +++ + L+
Sbjct: 139 DVMVAV--GEPAVMECQPPRGHPEPTISW----KKDGSPLD-----DKDERITIRGGKLM 187
Query: 998 VGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF---KPFEYKEHDFRMAPKFLTPL 1054
+ YT + + + G + E E P F+
Sbjct: 188 I-------TYTRK-----------SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP 229
Query: 1055 IDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
+ V SA C RG P P V W K+ E+ + + ++ TL IR+ + D
Sbjct: 230 SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDH----TLKIRKVTAGD 285
Query: 1115 AGTYTCRAVNELGEALAECKLEVRVP 1140
G+YTC A N +G+A A L V+ P
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQEP 311
Score = 50.4 bits (119), Expect = 9e-06
Identities = 67/305 (21%), Positives = 113/305 (37%), Gaps = 82/305 (26%)
Query: 863 PFQGKPRPQVVWTKGGAPLDTS--RVHVRTSDFDTVFFVRQAARSDSGEYE-LSVQIENM 919
P +G P P + W K G+PLD R+ +R + +SD+G+Y + +
Sbjct: 154 PPRGHPEPTISWKKDGSPLDDKDERITIRGGKL----MITYTRKSDAGKYVCVGTNMVGE 209
Query: 920 KDTATIRIRVVEKAG---PPINVMVK---------EVWGTNA-LVEWQAPKDDGNSEIMG 966
+++ + V+E+ P N+ V E G V W+ KDDG
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR--KDDGELPKSR 267
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y + R+ HT + + G+ + EN+ G +++
Sbjct: 268 YEI---------------RDDHT-LKIRKVTAGDMGSYTCVAENMVGKAEASATLT---- 307
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
+ P F+ D+VV G + C G+P+P + W
Sbjct: 308 -----------------VQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR---- 346
Query: 1087 EIREDPKFLITNYQ-------------GVLTL-NIRRPSPFDAGTYTCRAVNELGEALAE 1132
RE + L+ +YQ G LT+ N++R D G Y C+ +N G + +
Sbjct: 347 --REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRS---DVGYYICQTLNVAGSIITK 401
Query: 1133 CKLEV 1137
LEV
Sbjct: 402 AYLEV 406
Score = 49.7 bits (117), Expect = 2e-05
Identities = 71/335 (21%), Positives = 116/335 (34%), Gaps = 40/335 (11%)
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
VG N+ G E ++ + + P ++ P +L T V + +G P P
Sbjct: 202 VGTNMVGERE----SEVAELTVLERPSFVKRPSNLAVT----VDDSAEFKCEARGDPVPT 253
Query: 872 VVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
V W K L SR +R D +R+ D G Y + K A+ + V E
Sbjct: 254 VRWRKDDGELPKSRYEIRD---DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE 310
Query: 932 KAGPPINVMVK---EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
P + +VK +V V +Q + + + + + +R
Sbjct: 311 ----PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 366
Query: 989 TSCTVSDLIVGNEY-----YFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
+ DL + N Y+ T N+ G + + T I
Sbjct: 367 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-------------- 412
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
R P +++ V + L+C G P P ++W K+ + + + GV
Sbjct: 413 -RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV- 470
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L IR D G YTC A GEA +EV+
Sbjct: 471 -LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 504
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 102 bits (255), Expect = 2e-21
Identities = 130/499 (26%), Positives = 192/499 (38%), Gaps = 76/499 (15%)
Query: 283 PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV------KDEKCF 336
P+ T+ W K+G + + + GK I K DA V V + E
Sbjct: 198 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 253
Query: 337 TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKARY 395
EL V E P + P + V V D E E + V W KD EL K+RY
Sbjct: 254 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP-----KSRY 307
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNG----GQCEAELIVEEKQLEVLQDIADLTVK 451
+ D H L V D G Y + + A L V+E V++ D V
Sbjct: 308 EIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKP-RDQVVA 363
Query: 452 ASEQAVFKCEVSDEKVTGK-WYKNGVE--------VRPSKRITISHVGRFHKLVIDDVRP 502
F+CE + W + G + + S R ++S G L I +V+
Sbjct: 364 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQR 420
Query: 503 EDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKL 562
D G Y A S+ K +LE+ + + + PP I + N V V G +
Sbjct: 421 SDVGYYICQTLNVAGSIITKA-YLEV-TDVIADRPPPVIR-----QGPVNQTVAVDGTFV 473
Query: 563 RLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN 622
L TG P P W K + +T + R K+++ I A+ D GRYT +
Sbjct: 474 -LSCVATGSPVPTILWRKDGVLVSTQDSRI---KQLENGVLQIRYAKLGDTGRYTCIAST 529
Query: 623 PVGEDVASIFLQVVD---------------VPDPPEAVRITSVGEDWAILVWEPPMYDGG 667
P GE S +++V + +P P +T V + L W+P + G
Sbjct: 530 PSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGA 589
Query: 668 KPVTGYLVERKKKGS-QRWMKLNFEVFTETTYESTKMIEGI----LYEMRVFAVNAIGVS 722
P T Y++E S W + V TET+ I+G+ +Y V A NA G+S
Sbjct: 590 TP-TSYIIEAFSHASGSSWQTVAENVKTETS-----AIKGLKPNAIYLFLVRAANAYGIS 643
Query: 723 QPSMNTKPF--MPIAPTSE 739
PS + P + PTS+
Sbjct: 644 DPSQISDPVKTQDVLPTSQ 662
Score = 82.8 bits (203), Expect = 2e-15
Identities = 141/607 (23%), Positives = 214/607 (35%), Gaps = 99/607 (16%)
Query: 283 PDLTLKWFKNGQEIK-----PSSKYVFENVGKKRILTI--NKCTLADDAAYEVAVKDEKC 335
P T++W+K G+ ++ P S + G L I + + D+ Y ++
Sbjct: 95 PTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN--- 151
Query: 336 FTELFVKEPPVLIVTPLEDQ--------QVFVGDRVEMAVEVSEEGAQ--VMWMKDGVEL 385
+ V L V L D V VG+ M + + + W KDG L
Sbjct: 152 YLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL 211
Query: 386 TREDS--------FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
+D Y K D +++ + +++V E AEL V E+
Sbjct: 212 DDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEV----------AELTVLER 261
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLV 496
V + ++L V + A FKCE + V T +W K+ E+ P R I H L
Sbjct: 262 PSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDD---HTLK 316
Query: 497 IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVV 556
I V D G YT V + A + QEPP + + VV
Sbjct: 317 IRKVTAGDMGSYTCVAENMVGKAEASAT--------LTVQEPPHFVVKPRDQ------VV 362
Query: 557 VAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSS---FVIESAQRED 612
G + TG P P W + G + + + R S I + QR D
Sbjct: 363 ALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSD 422
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDV--PDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
G Y + N G + +L+V DV PP +R V + A+ G V
Sbjct: 423 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAV---------DGTFV 473
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG-----VSQPS 725
+ + W K V T+ + K +E + ++R + G S PS
Sbjct: 474 LSCVATGSPVPTILWRKDGVLVSTQDS--RIKQLENGVLQIRYAKLGDTGRYTCIASTPS 531
Query: 726 MNTK------------PFMPIAPT------SEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P PT S P V DV+ T TL W+P GA
Sbjct: 532 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 591
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y++E S E V+ +K L A LF V N G S+P+ ++
Sbjct: 592 TS-YIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 650
Query: 828 PVTIREI 834
PV +++
Sbjct: 651 PVKTQDV 657
Score = 64.3 bits (155), Expect = 6e-10
Identities = 136/634 (21%), Positives = 218/634 (34%), Gaps = 77/634 (12%)
Query: 426 GQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRI 484
G + L E+ +++ +DL V E A C+ T +WYK G V K
Sbjct: 55 GYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDD 114
Query: 485 TISHVGR-------FHKLVIDDVRPEDEGDYTFVPDGY---ALSLSAKLNFLEIKVEYVP 534
SH F ++V DEG Y V Y A+S +A L ++ ++
Sbjct: 115 PRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF-- 172
Query: 535 KQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSIT-GEPPPVATWLKGDEVFTTTEGRTR 593
+Q P + ++V G ++ G P P +W K + R
Sbjct: 173 RQNP-------------SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERIT 219
Query: 594 IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF-LQVVDVPD---PPEAVRITS 649
I +I ++ D G+Y TN VGE + + L V++ P P + +T
Sbjct: 220 IRG----GKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV 275
Query: 650 VGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILY 709
+D A E G PV R +K K +E+ + T + K+ G +
Sbjct: 276 --DDSAEFKCEAR----GDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMG 326
Query: 710 EMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGID 769
A N +G ++ S EP H +V+ D L + A G
Sbjct: 327 SYTCVAENMVGKAEASATLT-------VQEPPHFVVKP-RDQVVALGRTVTFQCEATGNP 378
Query: 770 GYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRV----VGVNIAGRSEPATL 825
+ + EGS+ + + P F+V TG + V VG I A
Sbjct: 379 QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ--TGDLTITNVQRSDVGYYICQTLNVAGS 436
Query: 826 AQPVTIREIAEPPKIRLPRHLRQTYIRK---VGEQLNLVVPFQGKPRPQVVWTKGGAPLD 882
E+ + R P +RQ + + V L G P P ++W K G +
Sbjct: 437 IITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVS 496
Query: 883 TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP------- 935
T ++ + + V +R A D+G Y + + T + I V E P
Sbjct: 497 TQDSRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPT 555
Query: 936 --------PINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNR 987
P V +V + WQ + G + + W V E +
Sbjct: 556 DPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK 615
Query: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVS 1021
+ + L Y F V N G+SD +S
Sbjct: 616 TETSAIKGLKPNAIYLFLVRAANAYGISDPSQIS 649
Score = 57.4 bits (137), Expect = 8e-08
Identities = 77/326 (23%), Positives = 128/326 (39%), Gaps = 52/326 (15%)
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS----RV 886
+R+ PP R+ H + K GE L +G+P P + W KGG ++T R
Sbjct: 61 LRQEDFPP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 117
Query: 887 HVRTSDFDTVFFVR----QAARSDSGEYELSVQI---ENMKDTATIRIRVVEK--AGPPI 937
H ++FF+R + +R D G Y + E + A++ + ++ P
Sbjct: 118 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPS 177
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI 997
+VMV G A++E Q P+ I K D ++ +++ + L+
Sbjct: 178 DVMVAV--GEPAVMECQPPRGHPEPTISW----KKDGSPLD-----DKDERITIRGGKLM 226
Query: 998 VGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF---KPFEYKEHDFRMAPKFLTPL 1054
+ YT + + + G + E E P F+
Sbjct: 227 I-------TYTRK-----------SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP 268
Query: 1055 IDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
+ V SA C RG P P V W K+ E+ + + ++ TL IR+ + D
Sbjct: 269 SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDH----TLKIRKVTAGD 324
Query: 1115 AGTYTCRAVNELGEALAECKLEVRVP 1140
G+YTC A N +G+A A L V+ P
Sbjct: 325 MGSYTCVAENMVGKAEASATLTVQEP 350
Score = 50.4 bits (119), Expect = 9e-06
Identities = 67/305 (21%), Positives = 113/305 (37%), Gaps = 82/305 (26%)
Query: 863 PFQGKPRPQVVWTKGGAPLDTS--RVHVRTSDFDTVFFVRQAARSDSGEYE-LSVQIENM 919
P +G P P + W K G+PLD R+ +R + +SD+G+Y + +
Sbjct: 193 PPRGHPEPTISWKKDGSPLDDKDERITIRGGKL----MITYTRKSDAGKYVCVGTNMVGE 248
Query: 920 KDTATIRIRVVEKAG---PPINVMVK---------EVWGTNA-LVEWQAPKDDGNSEIMG 966
+++ + V+E+ P N+ V E G V W+ KDDG
Sbjct: 249 RESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR--KDDGELPKSR 306
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y + R+ HT + + G+ + EN+ G +++
Sbjct: 307 YEI---------------RDDHT-LKIRKVTAGDMGSYTCVAENMVGKAEASATLT---- 346
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
+ P F+ D+VV G + C G+P+P + W
Sbjct: 347 -----------------VQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR---- 385
Query: 1087 EIREDPKFLITNYQ-------------GVLTL-NIRRPSPFDAGTYTCRAVNELGEALAE 1132
RE + L+ +YQ G LT+ N++R D G Y C+ +N G + +
Sbjct: 386 --REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRS---DVGYYICQTLNVAGSIITK 440
Query: 1133 CKLEV 1137
LEV
Sbjct: 441 AYLEV 445
Score = 49.7 bits (117), Expect = 2e-05
Identities = 71/335 (21%), Positives = 116/335 (34%), Gaps = 40/335 (11%)
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
VG N+ G E ++ + + P ++ P +L T V + +G P P
Sbjct: 241 VGTNMVGERE----SEVAELTVLERPSFVKRPSNLAVT----VDDSAEFKCEARGDPVPT 292
Query: 872 VVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
V W K L SR +R D +R+ D G Y + K A+ + V E
Sbjct: 293 VRWRKDDGELPKSRYEIRD---DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE 349
Query: 932 KAGPPINVMVK---EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
P + +VK +V V +Q + + + + + +R
Sbjct: 350 ----PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 405
Query: 989 TSCTVSDLIVGNEY-----YFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
+ DL + N Y+ T N+ G + + T I
Sbjct: 406 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-------------- 451
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
R P +++ V + L+C G P P ++W K+ + + + GV
Sbjct: 452 -RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV- 509
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L IR D G YTC A GEA +EV+
Sbjct: 510 -LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 543
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 102 bits (253), Expect = 3e-21
Identities = 125/522 (23%), Positives = 206/522 (39%), Gaps = 59/522 (11%)
Query: 284 DLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEV-------AVKDEKCF 336
DL++ W +NG I + G++ LTI+ T AD Y A + +
Sbjct: 324 DLSVTWKRNGVRITSG----LHSFGRR--LTISNPTSADTGPYVCEAALPGSAFEPARAT 377
Query: 337 TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQV-----MWMKDGVELTREDSF 391
LF+ EPP P + + VE V++ + V W KD + ++R +
Sbjct: 378 AFLFIIEPPYFTAEP----ESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQN- 432
Query: 392 KARYRFKKDGKRHILIFSDVVQEDRGRYQVITN--GGQCEAELIVEEKQLEVL--QDIAD 447
RY+ G I + ED G +Q + GG+ + ++ + + Q D
Sbjct: 433 -PRYKVLASGGLRI---QKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVD 488
Query: 448 LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHK--LVIDDVRPEDE 505
TV A+ +CEVS +K + S + I L I V +D
Sbjct: 489 TTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDA 548
Query: 506 GDYTFVPDGYALSLSAKLNFLEIKVEYVPKQ--EPPKIHLDCSGKTSENAIVVVAGNKLR 563
G+YT YA + LN + PP+ H VV+ G
Sbjct: 549 GNYTC----YAANTEGSLNASATLTVWNRTSIVHPPEDH------------VVIKGTTAT 592
Query: 564 LDVSITGEPPPVATWL-KGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTN 622
L T +P ++ K D V T +RI D S +I D G Y+ ++ +
Sbjct: 593 LHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKD-GSLLISQTWSGDIGDYSCEIVS 651
Query: 623 PVGEDVASIFLQVVDVPDPPEAVRIT--SVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
G D L+V+++P P+ + ++ S +L W P +DG P+ Y+VE +
Sbjct: 652 EGGNDSRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRP-FDGNSPILYYIVELSEN 710
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--PIAPTS 738
S + L+ T + + Y+ RV AVN +G Q S T M P++
Sbjct: 711 NSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSA 770
Query: 739 EPLHLIVEDVTDTTTTLKWRPPNRIGAGGI-DGYLVEYCLEG 779
P +++ T+ + ++W+PP G+ GY++ Y L G
Sbjct: 771 PPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAG 812
Score = 54.3 bits (129), Expect = 6e-07
Identities = 94/396 (23%), Positives = 150/396 (37%), Gaps = 49/396 (12%)
Query: 603 FVIESAQREDEGRYTIKVTNPVGEDVASIFLQVV------DVPDP-PEAVRITSVGEDWA 655
F IE + E ++ N VG A + +VV VP PE V +V
Sbjct: 1237 FTIEELEEWMEYELQMQAFNAVG---AGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQI 1293
Query: 656 ILVWEP-PMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEG----ILYE 710
+L W P D + GY + + K + + + + ++ G +LYE
Sbjct: 1294 LLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHI---VRGNHTQSALLAGLRKFVLYE 1350
Query: 711 MRVFAVNAIGVSQPSM-----NTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGA 765
++V A IG PS TK P P+ L+ +V T+ + W+PP
Sbjct: 1351 LQVLAFTRIGNGVPSTPLILERTKDDAP----GPPVRLVFPEVRLTSVRIVWQPPEEPN- 1405
Query: 766 GGIDGYLVEYCLEGSEEWVPANTEPVERCG-FTVKNLPTGARILFRVVGVNIAGRSEP-- 822
G I GY + Y L S E FT +L + +FR+ G EP
Sbjct: 1406 GIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLE 1465
Query: 823 ATLA------QPVTIREIAEPPKIRLPRHLRQTYIR-KVGEQLNLVVPFQGKPRPQVVWT 875
AT+ +P RE+ P R LR ++ G Q + P+ W
Sbjct: 1466 ATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQ 1525
Query: 876 KGGAPLD---TSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
+ + T+ V R F T + +R A +D G+ + S + E + +
Sbjct: 1526 TYSSSISHEATACVVDRLRPF-TSYKLRLKATNDIGDSDFSSETEAVTTLQDV------P 1578
Query: 933 AGPPINVMVKEVWGTNALVEWQAPKDDG-NSEIMGY 967
PP +V ++ L++WQ P+D+ N + GY
Sbjct: 1579 GEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGY 1614
Score = 51.6 bits (122), Expect = 4e-06
Identities = 142/643 (22%), Positives = 216/643 (33%), Gaps = 105/643 (16%)
Query: 246 KKAKVEVKKSAAFTKKLDPAYQVDRGNK--IKLMVEISDPDLTLKWFKNGQEIKPSSKYV 303
+K++V+V +F D V +G + L+ S P + WF+ G +I PS++
Sbjct: 181 RKSEVQVAYMGSFMDT-DQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIA 239
Query: 304 FENVGKKRILTINKCTLADDAAYEVAVKDEK-------CFTELFVKE--------PPVLI 348
+ + L I T +D AY V +EK F L + P ++
Sbjct: 240 ---ITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIV 296
Query: 349 VTPLEDQQVFVGDRVEMAVEVSE---EGAQVMWMKDGVELTREDSFKARYRFKKDGKRHI 405
V P V + S E V W ++GV +T + F G+R
Sbjct: 297 VPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRIT-----SGLHSF---GRR-- 346
Query: 406 LIFSDVVQEDRGRY--QVITNGGQCE-----AELIVEEKQLEVLQDIADLTVKASEQAVF 458
L S+ D G Y + G E A L + E + + ++ + E
Sbjct: 347 LTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDI 406
Query: 459 KCEVSDEKV-TGKWYKNGVEV----RPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPD 513
C+ + T +WYK+ + + P ++ S R KL RPED G +
Sbjct: 407 GCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKL-----RPEDSGIFQCFAS 461
Query: 514 GYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPP 573
+ + V Q P +D + AI LR +VS G P
Sbjct: 462 NEGGEIQTHTYLDVTNIAPVFTQRP----VDTTVTDGMTAI-------LRCEVS--GAPK 508
Query: 574 PVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFL 633
P TW + + + + R ++ I +D G YT N G AS L
Sbjct: 509 PAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATL 568
Query: 634 QV---VDVPDPPE---------AVRITSVGEDWAI---LVWEPPMYDGGKPVTGYLVERK 678
V + PPE A D + VW+ T +V K
Sbjct: 569 TVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEK 628
Query: 679 KKG---SQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIA 735
SQ W + E E + R+ + I + N + ++
Sbjct: 629 DGSLLISQTWSGDIGDYSCEIVSEGGN-------DSRMARLEVIELPHSPQN----LLVS 677
Query: 736 PTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG 795
P S H +V L W P G I Y+VE S V + E G
Sbjct: 678 PNSSHSHAVV---------LSWVRPFD-GNSPILYYIVELSENNSPWKVHLSNVGPEMTG 727
Query: 796 FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
TV L FRV VN GR + + + + E EPP
Sbjct: 728 VTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPE--EPP 768
Score = 48.5 bits (114), Expect = 4e-05
Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 7/96 (7%)
Query: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIRED----PKFLITNYQG 1101
+AP F +D V G +A L C V G PKP + W + + P+F++ G
Sbjct: 478 IAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGG 537
Query: 1102 VLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
L I DAG YTC A N G A L V
Sbjct: 538 ---LQIAPVFIQDAGNYTCYAANTEGSLNASATLTV 570
Score = 47.0 bits (110), Expect = 1e-04
Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 11/161 (6%)
Query: 873 VWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEK 932
VW K L S + D + Q D G+Y + E D+ R+ V+E
Sbjct: 608 VWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIEL 667
Query: 933 AGPPINVMV--KEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN---R 987
P N++V ++ W P DGNS I+ Y V+ ++ + + V+ N
Sbjct: 668 PHSPQNLLVSPNSSHSHAVVLSWVRP-FDGNSPILYYIVELSENNSP--WKVHLSNVGPE 724
Query: 988 HTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
T TVS L Y FRV N G S T+R++
Sbjct: 725 MTGVTVSGLTPARTYQFRVCAVNEVGRGQ---YSAETSRLM 762
Score = 42.4 bits (98), Expect = 0.003
Identities = 67/289 (23%), Positives = 106/289 (36%), Gaps = 32/289 (11%)
Query: 858 LNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIE 917
LNL+ P PRPQV W + G + S T + V SD+G Y VQ
Sbjct: 210 LNLL-PITSYPRPQVTWFREGHKIIPSNRIAITLENQLVILA--TTTSDAGAYY--VQAV 264
Query: 918 NMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK-----A 972
N K+ K P I++ + GT + GN ++ + A
Sbjct: 265 NEKNGEN-------KTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIA 317
Query: 973 DKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGI 1032
+ +E +V + T G R+ N P V + G
Sbjct: 318 SARPVEDLSVTWKRNGVRITSGLHSFGR----RLTISNPTSADTGPYVCEAAL----PGS 369
Query: 1033 TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALN--CAVRGHPKPKVVWMKNKMEIR- 1089
F+P F + P + T + + A ++ C G P P + W K+ + I
Sbjct: 370 AFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISR 429
Query: 1090 -EDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
++P++ + G L I++ P D+G + C A NE GE L+V
Sbjct: 430 LQNPRYKVLASGG---LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDV 475
Score = 42.4 bits (98), Expect = 0.003
Identities = 88/405 (21%), Positives = 154/405 (38%), Gaps = 55/405 (13%)
Query: 637 DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKG---SQRWMKLNFEVF 693
D+P P + I+++ A L + P YDG ++ ++VE + + W+ L +
Sbjct: 1068 DLPGAPSNLVISNISPRSATLQFRPG-YDGKTSISRWIVEGQVGAIGDEEEWVTL----Y 1122
Query: 694 TETTYESTKMIE------GILYEMRVFAVNAIGVS--QPSMNTKPFMPIAPTSEPLHLIV 745
E +M+E Y R+ VN +G S PS + P P + V
Sbjct: 1123 EEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTV 1182
Query: 746 EDVTDTTTTLKWRP-PNRIGAGGID--GYLVEYCLEGSEEWVPAN--TEPVERCGFTVKN 800
++T+ L+W P P+ G + GY ++Y + A ++ +ER FT++
Sbjct: 1183 RTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLER-EFTIEE 1241
Query: 801 LPTGARILFRVVGVNIAGRSEPATLAQPVTIREI-AEPPKIRLPRHLRQTYI----RKVG 855
L ++ N G + + + T + + P+ + T I V
Sbjct: 1242 LEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVP 1301
Query: 856 EQ------LNLVVPFQGK---PRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQA---A 903
EQ L + F+ K P P+ +G +R V + Q
Sbjct: 1302 EQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLR----KFVLYELQVLAFT 1357
Query: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
R +G + +E KD A GPP+ ++ EV T+ + WQ P ++ N
Sbjct: 1358 RIGNGVPSTPLILERTKDDA---------PGPPVRLVFPEVRLTSVRIVWQ-PPEEPNGI 1407
Query: 964 IMGYFV--QKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRV 1006
I+GY + + A + V T +DL + Y FR+
Sbjct: 1408 ILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRL 1452
Score = 41.6 bits (96), Expect = 0.004
Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 5/90 (5%)
Query: 639 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV---FTE 695
P P V +T + + E + G P TGY++E + W ++ T
Sbjct: 1903 PGSPRDVLVTKSASELTLQWTEG--HSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATS 1960
Query: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPS 725
T K+ +G+ YE RV AVN G +PS
Sbjct: 1961 YTLSLDKLRQGVTYEFRVVAVNEAGYGEPS 1990
Score = 40.8 bits (94), Expect = 0.007
Identities = 179/841 (21%), Positives = 298/841 (35%), Gaps = 105/841 (12%)
Query: 251 EVKKSAAFTKKLDPAY-QVDRGNKIKLMVE---------ISDPDLTLKWFKNGQEIKPSS 300
E ++ AF ++P Y + ++I VE + P TL+W+K+ I
Sbjct: 372 EPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQ 431
Query: 301 KYVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKE-PPVLIVTPLEDQ 355
++ + L I K D ++ +E + T L V PV P+ D
Sbjct: 432 NPRYKVLASGG-LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPV-DT 489
Query: 356 QVFVGDRVEMAVEVSEEGAQ---VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVV 412
V G + EVS GA + W ++ L R+ + G I + V
Sbjct: 490 TVTDGMTAILRCEVS--GAPKPAITWKRENHILASGSVRIPRFMLLESGGLQI---APVF 544
Query: 413 QEDRGRYQVI---TNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVS-DEKVT 468
+D G Y T G + + + ++ D V A C + D +V+
Sbjct: 545 IQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVS 604
Query: 469 GK--WYKNGVEVRPSK--RITISHVGRFHKLVIDDVRPEDEGDYT--FVPDGYALSLSAK 522
+ W K+ V + PS RI + G L+I D GDY+ V +G S A+
Sbjct: 605 LRYVWKKDNVALTPSSTSRIVVEKDG---SLLISQTWSGDIGDYSCEIVSEGGNDSRMAR 661
Query: 523 LNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVV-----VAGNKLRL----DVSITGEPP 573
L +E+ P+ L + +A+V+ GN L ++S P
Sbjct: 662 LEVIELP-------HSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPW 714
Query: 574 PVATWLKGDEVF-TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF 632
V G E+ T G T F + + G+Y+ + +
Sbjct: 715 KVHLSNVGPEMTGVTVSGLTPARTY----QFRVCAVNEVGRGQYSAETSR---------L 761
Query: 633 LQVVDVPDPPEAVRITSVGEDWAILV-WEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNF 690
+ + P P + S + +I+V W+PP V GY++ + G +
Sbjct: 762 MLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRN 821
Query: 691 EVFTETTY-ESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPF-MPIAPTSEPLHLIVEDV 748
E Y T +I YE++V A N G+ S + + PT+ P ++ E V
Sbjct: 822 ITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAV 881
Query: 749 TDTTTTLKWRPPNRIGAGGID-GYLVEYCLEGSEEWVPANTEPVERCGF---TVKNLPTG 804
TT W PP + GI+ GY + + E V T + G + NL
Sbjct: 882 NSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKF 941
Query: 805 ARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPF 864
V+ G P+T Q V +E K HL T I +++ P
Sbjct: 942 TAYFTSVLCFTTPGDGPPST-PQLVWTQE----DKPGAVGHLSFTEILDTSLKVSWQEPL 996
Query: 865 QGK---PRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKD 921
+ Q+ W G D+ H S T + S Y + V
Sbjct: 997 EKNGIITGYQISWEVYGRN-DSRLTHTLNS---TTHEYKIQGLSSLTTYTIDVAAVTAVG 1052
Query: 922 TATIRIRVVEKA------GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ---KA 972
T + + G P N+++ + +A ++++ P DG + I + V+ A
Sbjct: 1053 TGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFR-PGYDGKTSISRWIVEGQVGA 1111
Query: 973 DKKTMEWFNVYERNRHTSC---TVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILK 1029
EW +YE + +L Y FR+ NI G P ++R+++
Sbjct: 1112 IGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVG----PSPYSPSSRVIQ 1167
Query: 1030 T 1030
T
Sbjct: 1168 T 1168
Score = 33.9 bits (76), Expect = 0.91
Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 1053 PLIDRVVVAGYSAALNCAVRGHPKP--KVVWMKNKMEIR-EDPKFLITNYQGVLTLNIRR 1109
P D VV+ G +A L+C P+ + VW K+ + + ++ G +L I +
Sbjct: 579 PPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDG--SLLISQ 636
Query: 1110 PSPFDAGTYTCRAVNELGEALAECKLEV 1137
D G Y+C V+E G +LEV
Sbjct: 637 TWSGDIGDYSCEIVSEGGNDSRMARLEV 664
Score = 33.5 bits (75), Expect = 1.2
Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 10/95 (10%)
Query: 1046 MAPKFLT-PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104
+AP F T P + ++ + G L C G + WM++ E+ T Y
Sbjct: 102 VAPYFKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSEL--------TTYSSEYK 153
Query: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRV 1139
I DAG Y C N +G AL + K EV+V
Sbjct: 154 YIIPSLQKLDAGFYRCVVRNRMG-ALLQRKSEVQV 187
Score = 31.6 bits (70), Expect = 4.5
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 1057 RVVVAGYSAALNCA-VRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDA 1115
+ V G +A LN + +P+P+V W + +I + IT ++ L + DA
Sbjct: 200 KTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLVIL---ATTTSDA 256
Query: 1116 GTYTCRAVNE 1125
G Y +AVNE
Sbjct: 257 GAYYVQAVNE 266
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 100 bits (249), Expect = 8e-21
Identities = 131/504 (25%), Positives = 195/504 (38%), Gaps = 83/504 (16%)
Query: 283 PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV------KDEKCF 336
P+ T+ W K+G + + + GK I K DA V V + E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 337 TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKARY 395
EL V E P + P + V V D E E + V W KD EL K+RY
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP-----KSRY 268
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNG--GQCEAELIVEEKQLEVLQDIADLTVKAS 453
+ D H L V D G Y + G+ EA + ++V + VK
Sbjct: 269 EIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLT---VQVGSEPPHFVVKPR 322
Query: 454 EQAV-------FKCEVSDEKVTGK-WYKNGVE--------VRPSKRITISHVGRFHKLVI 497
+Q V F+CE + W + G + + S R ++S G L I
Sbjct: 323 DQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTI 379
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
+V+ D G Y A S+ K +LE+ + + + PP I + N V V
Sbjct: 380 TNVQRSDVGYYICQTLNVAGSIITKA-YLEV-TDVIADRPPPVIR-----QGPVNQTVAV 432
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
G + L TG P P W K + +T + R K+++ I A+ D GRYT
Sbjct: 433 DGTFV-LSCVATGSPVPTILWRKDGVLVSTQDSRI---KQLENGVLQIRYAKLGDTGRYT 488
Query: 618 IKVTNPVGEDVASIFLQVVD---------------VPDPPEAVRITSVGEDWAILVWEPP 662
+ P GE S +++V + +P P +T V + L W+P
Sbjct: 489 CIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPN 548
Query: 663 MYDGGKPVTGYLVERKKKGS-QRWMKLNFEVFTETTYESTKMIEGI----LYEMRVFAVN 717
+ G P T Y++E S W + V TET+ I+G+ +Y V A N
Sbjct: 549 LNSGATP-TSYIIEAFSHASGSSWQTVAENVKTETS-----AIKGLKPNAIYLFLVRAAN 602
Query: 718 AIGVSQPSMNTKPF--MPIAPTSE 739
A G+S PS + P + PTS+
Sbjct: 603 AYGISDPSQISDPVKTQDVLPTSQ 626
Score = 82.0 bits (201), Expect = 3e-15
Identities = 142/607 (23%), Positives = 216/607 (35%), Gaps = 96/607 (15%)
Query: 283 PDLTLKWFKNGQEIK-----PSSKYVFENVGKKRILTI--NKCTLADDAAYEVAVKDEKC 335
P T++W+K G+ ++ P S + G L I + + D+ Y ++
Sbjct: 56 PTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN--- 112
Query: 336 FTELFVKEPPVLIVTPLEDQ--------QVFVGDRVEMAVEVSEEGAQ--VMWMKDGVEL 385
+ V L V L D V VG+ M + + + W KDG L
Sbjct: 113 YLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL 172
Query: 386 TREDS--------FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
+D Y K D +++ + +++V E AEL V E+
Sbjct: 173 DDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEV----------AELTVLER 222
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLV 496
V + ++L V + A FKCE + V T +W K+ E+ P R I H L
Sbjct: 223 PSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDD---HTLK 277
Query: 497 IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVV 556
I V D G YT V + A L ++V EPP + + VV
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASAT-LTVQVG----SEPPHFVVKPRDQ------VV 326
Query: 557 VAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSS---FVIESAQRED 612
G + TG P P W + G + + + R S I + QR D
Sbjct: 327 ALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSD 386
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDV--PDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
G Y + N G + +L+V DV PP +R V + A+ G V
Sbjct: 387 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAV---------DGTFV 437
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG-----VSQPS 725
+ + W K V T+ + K +E + ++R + G S PS
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDS--RIKQLENGVLQIRYAKLGDTGRYTCIASTPS 495
Query: 726 MNTK------------PFMPIAPT------SEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P PT S P V DV+ T TL W+P GA
Sbjct: 496 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 555
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y++E S E V+ +K L A LF V N G S+P+ ++
Sbjct: 556 -TSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 614
Query: 828 PVTIREI 834
PV +++
Sbjct: 615 PVKTQDV 621
Score = 66.6 bits (161), Expect = 1e-10
Identities = 134/619 (21%), Positives = 216/619 (34%), Gaps = 74/619 (11%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR-------F 492
+++ +DL V E A C+ T +WYK G V K SH F
Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF 90
Query: 493 HKLVIDDVRPEDEGDYTFVPDGY---ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
++V DEG Y V Y A+S +A L ++ ++ +Q P
Sbjct: 91 LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF--RQNP----------- 137
Query: 550 SENAIVVVAGNKLRLDVSIT-GEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
+ ++V G ++ G P P +W K + R I +I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMITYT 191
Query: 609 QREDEGRYTIKVTNPVGEDVASIF-LQVVDVPD---PPEAVRITSVGEDWAILVWEPPMY 664
++ D G+Y TN VGE + + L V++ P P + +T +D A E
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEAR-- 247
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
G PV R +K K +E+ + T + K+ G + A N +G ++
Sbjct: 248 --GDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEA 302
Query: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
S + + SEP H +V+ D L + A G + + EGS+ +
Sbjct: 303 SAT----LTVQVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 785 PANTEPVERCGFTVKNLPTGARILFRV----VGVNIAGRSEPATLAQPVTIREIAEPPKI 840
+ P F+V TG + V VG I A E+ +
Sbjct: 358 FSYQPPQSSSRFSVSQ--TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD 415
Query: 841 RLPRHLRQTYIRK---VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
R P +RQ + + V L G P P ++W K G + T ++ + + V
Sbjct: 416 RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVL 474
Query: 898 FVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP---------------PINVMVK 942
+R A D+G Y + + T + I V E P P V
Sbjct: 475 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVT 534
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
+V + WQ + G + + W V E + + + L Y
Sbjct: 535 DVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIY 594
Query: 1003 YFRVYTENICGLSDSPGVS 1021
F V N G+SD +S
Sbjct: 595 LFLVRAANAYGISDPSQIS 613
Score = 57.0 bits (136), Expect = 1e-07
Identities = 77/325 (23%), Positives = 128/325 (39%), Gaps = 52/325 (16%)
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS----RV 886
+R+ PP R+ H + K GE L +G+P P + W KGG ++T R
Sbjct: 22 LRQEDFPP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 887 HVRTSDFDTVFFVR----QAARSDSGEYELSVQI---ENMKDTATIRIRVVEK--AGPPI 937
H ++FF+R + +R D G Y + E + A++ + ++ P
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPS 138
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI 997
+VMV G A++E Q P+ I K D ++ +++ + L+
Sbjct: 139 DVMVAV--GEPAVMECQPPRGHPEPTISW----KKDGSPLD-----DKDERITIRGGKLM 187
Query: 998 VGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF---KPFEYKEHDFRMAPKFLTPL 1054
+ YT + + + G + E E P F+
Sbjct: 188 I-------TYTRK-----------SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP 229
Query: 1055 IDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
+ V SA C RG P P V W K+ E+ + + ++ TL IR+ + D
Sbjct: 230 SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDH----TLKIRKVTAGD 285
Query: 1115 AGTYTCRAVNELGEALAECKLEVRV 1139
G+YTC A N +G+A A L V+V
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQV 310
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 79/305 (25%)
Query: 863 PFQGKPRPQVVWTKGGAPLDTS--RVHVRTSDFDTVFFVRQAARSDSGEYE-LSVQIENM 919
P +G P P + W K G+PLD R+ +R + +SD+G+Y + +
Sbjct: 154 PPRGHPEPTISWKKDGSPLDDKDERITIRGGKL----MITYTRKSDAGKYVCVGTNMVGE 209
Query: 920 KDTATIRIRVVEKAG---PPINVMVK---------EVWGTNA-LVEWQAPKDDGNSEIMG 966
+++ + V+E+ P N+ V E G V W+ KDDG
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR--KDDGELPKSR 267
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y + R+ HT + + G+ + EN+ G +++
Sbjct: 268 YEI---------------RDDHT-LKIRKVTAGDMGSYTCVAENMVGKAEASAT------ 305
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
L + +P P F+ D+VV G + C G+P+P + W
Sbjct: 306 -LTVQVGSEP-----------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR---- 349
Query: 1087 EIREDPKFLITNYQ-------------GVLTL-NIRRPSPFDAGTYTCRAVNELGEALAE 1132
RE + L+ +YQ G LT+ N++R D G Y C+ +N G + +
Sbjct: 350 --REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRS---DVGYYICQTLNVAGSIITK 404
Query: 1133 CKLEV 1137
LEV
Sbjct: 405 AYLEV 409
Score = 50.8 bits (120), Expect = 7e-06
Identities = 71/335 (21%), Positives = 117/335 (34%), Gaps = 37/335 (11%)
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
VG N+ G E ++ + + P ++ P +L T V + +G P P
Sbjct: 202 VGTNMVGERE----SEVAELTVLERPSFVKRPSNLAVT----VDDSAEFKCEARGDPVPT 253
Query: 872 VVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
V W K L SR +R D +R+ D G Y + K A+ + V
Sbjct: 254 VRWRKDDGELPKSRYEIRD---DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV 310
Query: 932 KAGPPINVMVK---EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
+ PP + +VK +V V +Q + + + + + +R
Sbjct: 311 GSEPP-HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 369
Query: 989 TSCTVSDLIVGNEY-----YFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
+ DL + N Y+ T N+ G + + T I
Sbjct: 370 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-------------- 415
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
R P +++ V + L+C G P P ++W K+ + + + GV
Sbjct: 416 -RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV- 473
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L IR D G YTC A GEA +EV+
Sbjct: 474 -LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 100 bits (249), Expect = 8e-21
Identities = 131/504 (25%), Positives = 195/504 (38%), Gaps = 83/504 (16%)
Query: 283 PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV------KDEKCF 336
P+ T+ W K+G + + + GK I K DA V V + E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 337 TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKARY 395
EL V E P + P + V V D E E + V W KD EL K+RY
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP-----KSRY 268
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNG--GQCEAELIVEEKQLEVLQDIADLTVKAS 453
+ D H L V D G Y + G+ EA + ++V + VK
Sbjct: 269 EIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLT---VQVGSEPPHFVVKPR 322
Query: 454 EQAV-------FKCEVSDEKVTGK-WYKNGVE--------VRPSKRITISHVGRFHKLVI 497
+Q V F+CE + W + G + + S R ++S G L I
Sbjct: 323 DQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTI 379
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
+V+ D G Y A S+ K +LE+ + + + PP I + N V V
Sbjct: 380 TNVQRSDVGYYICQTLNVAGSIITKA-YLEV-TDVIADRPPPVIR-----QGPVNQTVAV 432
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
G + L TG P P W K + +T + R K+++ I A+ D GRYT
Sbjct: 433 DGTFV-LSCVATGSPVPTILWRKDGVLVSTQDSRI---KQLENGVLQIRYAKLGDTGRYT 488
Query: 618 IKVTNPVGEDVASIFLQVVD---------------VPDPPEAVRITSVGEDWAILVWEPP 662
+ P GE S +++V + +P P +T V + L W+P
Sbjct: 489 CIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPN 548
Query: 663 MYDGGKPVTGYLVERKKKGS-QRWMKLNFEVFTETTYESTKMIEGI----LYEMRVFAVN 717
+ G P T Y++E S W + V TET+ I+G+ +Y V A N
Sbjct: 549 LNSGATP-TSYIIEAFSHASGSSWQTVAENVKTETS-----AIKGLKPNAIYLFLVRAAN 602
Query: 718 AIGVSQPSMNTKPF--MPIAPTSE 739
A G+S PS + P + PTS+
Sbjct: 603 AYGISDPSQISDPVKTQDVLPTSQ 626
Score = 82.0 bits (201), Expect = 3e-15
Identities = 142/607 (23%), Positives = 216/607 (35%), Gaps = 96/607 (15%)
Query: 283 PDLTLKWFKNGQEIK-----PSSKYVFENVGKKRILTI--NKCTLADDAAYEVAVKDEKC 335
P T++W+K G+ ++ P S + G L I + + D+ Y ++
Sbjct: 56 PTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN--- 112
Query: 336 FTELFVKEPPVLIVTPLEDQ--------QVFVGDRVEMAVEVSEEGAQ--VMWMKDGVEL 385
+ V L V L D V VG+ M + + + W KDG L
Sbjct: 113 YLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL 172
Query: 386 TREDS--------FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
+D Y K D +++ + +++V E AEL V E+
Sbjct: 173 DDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEV----------AELTVLER 222
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLV 496
V + ++L V + A FKCE + V T +W K+ E+ P R I H L
Sbjct: 223 PSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDD---HTLK 277
Query: 497 IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVV 556
I V D G YT V + A L ++V EPP + + VV
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASAT-LTVQVG----SEPPHFVVKPRDQ------VV 326
Query: 557 VAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSS---FVIESAQRED 612
G + TG P P W + G + + + R S I + QR D
Sbjct: 327 ALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSD 386
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDV--PDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
G Y + N G + +L+V DV PP +R V + A+ G V
Sbjct: 387 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAV---------DGTFV 437
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG-----VSQPS 725
+ + W K V T+ + K +E + ++R + G S PS
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDS--RIKQLENGVLQIRYAKLGDTGRYTCIASTPS 495
Query: 726 MNTK------------PFMPIAPT------SEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P PT S P V DV+ T TL W+P GA
Sbjct: 496 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 555
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y++E S E V+ +K L A LF V N G S+P+ ++
Sbjct: 556 -TSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 614
Query: 828 PVTIREI 834
PV +++
Sbjct: 615 PVKTQDV 621
Score = 66.6 bits (161), Expect = 1e-10
Identities = 134/619 (21%), Positives = 216/619 (34%), Gaps = 74/619 (11%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR-------F 492
+++ +DL V E A C+ T +WYK G V K SH F
Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF 90
Query: 493 HKLVIDDVRPEDEGDYTFVPDGY---ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
++V DEG Y V Y A+S +A L ++ ++ +Q P
Sbjct: 91 LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF--RQNP----------- 137
Query: 550 SENAIVVVAGNKLRLDVSIT-GEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
+ ++V G ++ G P P +W K + R I +I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMITYT 191
Query: 609 QREDEGRYTIKVTNPVGEDVASIF-LQVVDVPD---PPEAVRITSVGEDWAILVWEPPMY 664
++ D G+Y TN VGE + + L V++ P P + +T +D A E
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEAR-- 247
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
G PV R +K K +E+ + T + K+ G + A N +G ++
Sbjct: 248 --GDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEA 302
Query: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
S + + SEP H +V+ D L + A G + + EGS+ +
Sbjct: 303 SAT----LTVQVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 785 PANTEPVERCGFTVKNLPTGARILFRV----VGVNIAGRSEPATLAQPVTIREIAEPPKI 840
+ P F+V TG + V VG I A E+ +
Sbjct: 358 FSYQPPQSSSRFSVSQ--TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD 415
Query: 841 RLPRHLRQTYIRK---VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
R P +RQ + + V L G P P ++W K G + T ++ + + V
Sbjct: 416 RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVL 474
Query: 898 FVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP---------------PINVMVK 942
+R A D+G Y + + T + I V E P P V
Sbjct: 475 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVT 534
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
+V + WQ + G + + W V E + + + L Y
Sbjct: 535 DVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIY 594
Query: 1003 YFRVYTENICGLSDSPGVS 1021
F V N G+SD +S
Sbjct: 595 LFLVRAANAYGISDPSQIS 613
Score = 57.0 bits (136), Expect = 1e-07
Identities = 77/325 (23%), Positives = 128/325 (39%), Gaps = 52/325 (16%)
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS----RV 886
+R+ PP R+ H + K GE L +G+P P + W KGG ++T R
Sbjct: 22 LRQEDFPP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 887 HVRTSDFDTVFFVR----QAARSDSGEYELSVQI---ENMKDTATIRIRVVEK--AGPPI 937
H ++FF+R + +R D G Y + E + A++ + ++ P
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPS 138
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI 997
+VMV G A++E Q P+ I K D ++ +++ + L+
Sbjct: 139 DVMVAV--GEPAVMECQPPRGHPEPTISW----KKDGSPLD-----DKDERITIRGGKLM 187
Query: 998 VGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF---KPFEYKEHDFRMAPKFLTPL 1054
+ YT + + + G + E E P F+
Sbjct: 188 I-------TYTRK-----------SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP 229
Query: 1055 IDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
+ V SA C RG P P V W K+ E+ + + ++ TL IR+ + D
Sbjct: 230 SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDH----TLKIRKVTAGD 285
Query: 1115 AGTYTCRAVNELGEALAECKLEVRV 1139
G+YTC A N +G+A A L V+V
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQV 310
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 79/305 (25%)
Query: 863 PFQGKPRPQVVWTKGGAPLDTS--RVHVRTSDFDTVFFVRQAARSDSGEYE-LSVQIENM 919
P +G P P + W K G+PLD R+ +R + +SD+G+Y + +
Sbjct: 154 PPRGHPEPTISWKKDGSPLDDKDERITIRGGKL----MITYTRKSDAGKYVCVGTNMVGE 209
Query: 920 KDTATIRIRVVEKAG---PPINVMVK---------EVWGTNA-LVEWQAPKDDGNSEIMG 966
+++ + V+E+ P N+ V E G V W+ KDDG
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR--KDDGELPKSR 267
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y + R+ HT + + G+ + EN+ G +++
Sbjct: 268 YEI---------------RDDHT-LKIRKVTAGDMGSYTCVAENMVGKAEASAT------ 305
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
L + +P P F+ D+VV G + C G+P+P + W
Sbjct: 306 -LTVQVGSEP-----------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR---- 349
Query: 1087 EIREDPKFLITNYQ-------------GVLTL-NIRRPSPFDAGTYTCRAVNELGEALAE 1132
RE + L+ +YQ G LT+ N++R D G Y C+ +N G + +
Sbjct: 350 --REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRS---DVGYYICQTLNVAGSIITK 404
Query: 1133 CKLEV 1137
LEV
Sbjct: 405 AYLEV 409
Score = 50.8 bits (120), Expect = 7e-06
Identities = 71/335 (21%), Positives = 117/335 (34%), Gaps = 37/335 (11%)
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
VG N+ G E ++ + + P ++ P +L T V + +G P P
Sbjct: 202 VGTNMVGERE----SEVAELTVLERPSFVKRPSNLAVT----VDDSAEFKCEARGDPVPT 253
Query: 872 VVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
V W K L SR +R D +R+ D G Y + K A+ + V
Sbjct: 254 VRWRKDDGELPKSRYEIRD---DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV 310
Query: 932 KAGPPINVMVK---EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
+ PP + +VK +V V +Q + + + + + +R
Sbjct: 311 GSEPP-HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 369
Query: 989 TSCTVSDLIVGNEY-----YFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
+ DL + N Y+ T N+ G + + T I
Sbjct: 370 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-------------- 415
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
R P +++ V + L+C G P P ++W K+ + + + GV
Sbjct: 416 -RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV- 473
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L IR D G YTC A GEA +EV+
Sbjct: 474 -LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 100 bits (249), Expect = 8e-21
Identities = 131/504 (25%), Positives = 195/504 (38%), Gaps = 83/504 (16%)
Query: 283 PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV------KDEKCF 336
P+ T+ W K+G + + + GK I K DA V V + E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 337 TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKARY 395
EL V E P + P + V V D E E + V W KD EL K+RY
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP-----KSRY 268
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNG--GQCEAELIVEEKQLEVLQDIADLTVKAS 453
+ D H L V D G Y + G+ EA + ++V + VK
Sbjct: 269 EIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLT---VQVGSEPPHFVVKPR 322
Query: 454 EQAV-------FKCEVSDEKVTGK-WYKNGVE--------VRPSKRITISHVGRFHKLVI 497
+Q V F+CE + W + G + + S R ++S G L I
Sbjct: 323 DQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTI 379
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
+V+ D G Y A S+ K +LE+ + + + PP I + N V V
Sbjct: 380 TNVQRSDVGYYICQTLNVAGSIITKA-YLEV-TDVIADRPPPVIR-----QGPVNQTVAV 432
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
G + L TG P P W K + +T + R K+++ I A+ D GRYT
Sbjct: 433 DGTFV-LSCVATGSPVPTILWRKDGVLVSTQDSRI---KQLENGVLQIRYAKLGDTGRYT 488
Query: 618 IKVTNPVGEDVASIFLQVVD---------------VPDPPEAVRITSVGEDWAILVWEPP 662
+ P GE S +++V + +P P +T V + L W+P
Sbjct: 489 CIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPN 548
Query: 663 MYDGGKPVTGYLVERKKKGS-QRWMKLNFEVFTETTYESTKMIEGI----LYEMRVFAVN 717
+ G P T Y++E S W + V TET+ I+G+ +Y V A N
Sbjct: 549 LNSGATP-TSYIIEAFSHASGSSWQTVAENVKTETS-----AIKGLKPNAIYLFLVRAAN 602
Query: 718 AIGVSQPSMNTKPF--MPIAPTSE 739
A G+S PS + P + PTS+
Sbjct: 603 AYGISDPSQISDPVKTQDVLPTSQ 626
Score = 82.0 bits (201), Expect = 3e-15
Identities = 142/607 (23%), Positives = 216/607 (35%), Gaps = 96/607 (15%)
Query: 283 PDLTLKWFKNGQEIK-----PSSKYVFENVGKKRILTI--NKCTLADDAAYEVAVKDEKC 335
P T++W+K G+ ++ P S + G L I + + D+ Y ++
Sbjct: 56 PTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN--- 112
Query: 336 FTELFVKEPPVLIVTPLEDQ--------QVFVGDRVEMAVEVSEEGAQ--VMWMKDGVEL 385
+ V L V L D V VG+ M + + + W KDG L
Sbjct: 113 YLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL 172
Query: 386 TREDS--------FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
+D Y K D +++ + +++V E AEL V E+
Sbjct: 173 DDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEV----------AELTVLER 222
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLV 496
V + ++L V + A FKCE + V T +W K+ E+ P R I H L
Sbjct: 223 PSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDD---HTLK 277
Query: 497 IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVV 556
I V D G YT V + A L ++V EPP + + VV
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASAT-LTVQVG----SEPPHFVVKPRDQ------VV 326
Query: 557 VAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSS---FVIESAQRED 612
G + TG P P W + G + + + R S I + QR D
Sbjct: 327 ALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSD 386
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDV--PDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
G Y + N G + +L+V DV PP +R V + A+ G V
Sbjct: 387 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAV---------DGTFV 437
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG-----VSQPS 725
+ + W K V T+ + K +E + ++R + G S PS
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDS--RIKQLENGVLQIRYAKLGDTGRYTCIASTPS 495
Query: 726 MNTK------------PFMPIAPT------SEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P PT S P V DV+ T TL W+P GA
Sbjct: 496 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 555
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y++E S E V+ +K L A LF V N G S+P+ ++
Sbjct: 556 -TSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 614
Query: 828 PVTIREI 834
PV +++
Sbjct: 615 PVKTQDV 621
Score = 66.6 bits (161), Expect = 1e-10
Identities = 134/619 (21%), Positives = 216/619 (34%), Gaps = 74/619 (11%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR-------F 492
+++ +DL V E A C+ T +WYK G V K SH F
Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF 90
Query: 493 HKLVIDDVRPEDEGDYTFVPDGY---ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
++V DEG Y V Y A+S +A L ++ ++ +Q P
Sbjct: 91 LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF--RQNP----------- 137
Query: 550 SENAIVVVAGNKLRLDVSIT-GEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
+ ++V G ++ G P P +W K + R I +I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMITYT 191
Query: 609 QREDEGRYTIKVTNPVGEDVASIF-LQVVDVPD---PPEAVRITSVGEDWAILVWEPPMY 664
++ D G+Y TN VGE + + L V++ P P + +T +D A E
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEAR-- 247
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
G PV R +K K +E+ + T + K+ G + A N +G ++
Sbjct: 248 --GDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEA 302
Query: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
S + + SEP H +V+ D L + A G + + EGS+ +
Sbjct: 303 SAT----LTVQVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 785 PANTEPVERCGFTVKNLPTGARILFRV----VGVNIAGRSEPATLAQPVTIREIAEPPKI 840
+ P F+V TG + V VG I A E+ +
Sbjct: 358 FSYQPPQSSSRFSVSQ--TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD 415
Query: 841 RLPRHLRQTYIRK---VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
R P +RQ + + V L G P P ++W K G + T ++ + + V
Sbjct: 416 RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVL 474
Query: 898 FVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP---------------PINVMVK 942
+R A D+G Y + + T + I V E P P V
Sbjct: 475 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVT 534
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
+V + WQ + G + + W V E + + + L Y
Sbjct: 535 DVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIY 594
Query: 1003 YFRVYTENICGLSDSPGVS 1021
F V N G+SD +S
Sbjct: 595 LFLVRAANAYGISDPSQIS 613
Score = 57.0 bits (136), Expect = 1e-07
Identities = 77/325 (23%), Positives = 128/325 (39%), Gaps = 52/325 (16%)
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS----RV 886
+R+ PP R+ H + K GE L +G+P P + W KGG ++T R
Sbjct: 22 LRQEDFPP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 887 HVRTSDFDTVFFVR----QAARSDSGEYELSVQI---ENMKDTATIRIRVVEK--AGPPI 937
H ++FF+R + +R D G Y + E + A++ + ++ P
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPS 138
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI 997
+VMV G A++E Q P+ I K D ++ +++ + L+
Sbjct: 139 DVMVAV--GEPAVMECQPPRGHPEPTISW----KKDGSPLD-----DKDERITIRGGKLM 187
Query: 998 VGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF---KPFEYKEHDFRMAPKFLTPL 1054
+ YT + + + G + E E P F+
Sbjct: 188 I-------TYTRK-----------SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP 229
Query: 1055 IDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
+ V SA C RG P P V W K+ E+ + + ++ TL IR+ + D
Sbjct: 230 SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDH----TLKIRKVTAGD 285
Query: 1115 AGTYTCRAVNELGEALAECKLEVRV 1139
G+YTC A N +G+A A L V+V
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQV 310
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 79/305 (25%)
Query: 863 PFQGKPRPQVVWTKGGAPLDTS--RVHVRTSDFDTVFFVRQAARSDSGEYE-LSVQIENM 919
P +G P P + W K G+PLD R+ +R + +SD+G+Y + +
Sbjct: 154 PPRGHPEPTISWKKDGSPLDDKDERITIRGGKL----MITYTRKSDAGKYVCVGTNMVGE 209
Query: 920 KDTATIRIRVVEKAG---PPINVMVK---------EVWGTNA-LVEWQAPKDDGNSEIMG 966
+++ + V+E+ P N+ V E G V W+ KDDG
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR--KDDGELPKSR 267
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y + R+ HT + + G+ + EN+ G +++
Sbjct: 268 YEI---------------RDDHT-LKIRKVTAGDMGSYTCVAENMVGKAEASAT------ 305
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
L + +P P F+ D+VV G + C G+P+P + W
Sbjct: 306 -LTVQVGSEP-----------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR---- 349
Query: 1087 EIREDPKFLITNYQ-------------GVLTL-NIRRPSPFDAGTYTCRAVNELGEALAE 1132
RE + L+ +YQ G LT+ N++R D G Y C+ +N G + +
Sbjct: 350 --REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRS---DVGYYICQTLNVAGSIITK 404
Query: 1133 CKLEV 1137
LEV
Sbjct: 405 AYLEV 409
Score = 50.8 bits (120), Expect = 7e-06
Identities = 71/335 (21%), Positives = 117/335 (34%), Gaps = 37/335 (11%)
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
VG N+ G E ++ + + P ++ P +L T V + +G P P
Sbjct: 202 VGTNMVGERE----SEVAELTVLERPSFVKRPSNLAVT----VDDSAEFKCEARGDPVPT 253
Query: 872 VVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
V W K L SR +R D +R+ D G Y + K A+ + V
Sbjct: 254 VRWRKDDGELPKSRYEIRD---DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV 310
Query: 932 KAGPPINVMVK---EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
+ PP + +VK +V V +Q + + + + + +R
Sbjct: 311 GSEPP-HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 369
Query: 989 TSCTVSDLIVGNEY-----YFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
+ DL + N Y+ T N+ G + + T I
Sbjct: 370 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-------------- 415
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
R P +++ V + L+C G P P ++W K+ + + + GV
Sbjct: 416 -RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV- 473
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L IR D G YTC A GEA +EV+
Sbjct: 474 -LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 100 bits (249), Expect = 8e-21
Identities = 131/504 (25%), Positives = 195/504 (38%), Gaps = 83/504 (16%)
Query: 283 PDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV------KDEKCF 336
P+ T+ W K+G + + + GK I K DA V V + E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 337 TELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQ-VMWMKDGVELTREDSFKARY 395
EL V E P + P + V V D E E + V W KD EL K+RY
Sbjct: 215 AELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP-----KSRY 268
Query: 396 RFKKDGKRHILIFSDVVQEDRGRYQVITNG--GQCEAELIVEEKQLEVLQDIADLTVKAS 453
+ D H L V D G Y + G+ EA + ++V + VK
Sbjct: 269 EIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLT---VQVGSEPPHFVVKPR 322
Query: 454 EQAV-------FKCEVSDEKVTGK-WYKNGVE--------VRPSKRITISHVGRFHKLVI 497
+Q V F+CE + W + G + + S R ++S G L I
Sbjct: 323 DQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTI 379
Query: 498 DDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 557
+V+ D G Y A S+ K +LE+ + + + PP I + N V V
Sbjct: 380 TNVQRSDVGYYICQTLNVAGSIITKA-YLEV-TDVIADRPPPVIR-----QGPVNQTVAV 432
Query: 558 AGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617
G + L TG P P W K + +T + R K+++ I A+ D GRYT
Sbjct: 433 DGTFV-LSCVATGSPVPTILWRKDGVLVSTQDSRI---KQLENGVLQIRYAKLGDTGRYT 488
Query: 618 IKVTNPVGEDVASIFLQVVD---------------VPDPPEAVRITSVGEDWAILVWEPP 662
+ P GE S +++V + +P P +T V + L W+P
Sbjct: 489 CIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPN 548
Query: 663 MYDGGKPVTGYLVERKKKGS-QRWMKLNFEVFTETTYESTKMIEGI----LYEMRVFAVN 717
+ G P T Y++E S W + V TET+ I+G+ +Y V A N
Sbjct: 549 LNSGATP-TSYIIEAFSHASGSSWQTVAENVKTETS-----AIKGLKPNAIYLFLVRAAN 602
Query: 718 AIGVSQPSMNTKPF--MPIAPTSE 739
A G+S PS + P + PTS+
Sbjct: 603 AYGISDPSQISDPVKTQDVLPTSQ 626
Score = 82.0 bits (201), Expect = 3e-15
Identities = 142/607 (23%), Positives = 216/607 (35%), Gaps = 96/607 (15%)
Query: 283 PDLTLKWFKNGQEIK-----PSSKYVFENVGKKRILTI--NKCTLADDAAYEVAVKDEKC 335
P T++W+K G+ ++ P S + G L I + + D+ Y ++
Sbjct: 56 PTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARN--- 112
Query: 336 FTELFVKEPPVLIVTPLEDQ--------QVFVGDRVEMAVEVSEEGAQ--VMWMKDGVEL 385
+ V L V L D V VG+ M + + + W KDG L
Sbjct: 113 YLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL 172
Query: 386 TREDS--------FKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEK 437
+D Y K D +++ + +++V E AEL V E+
Sbjct: 173 DDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEV----------AELTVLER 222
Query: 438 QLEVLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLV 496
V + ++L V + A FKCE + V T +W K+ E+ P R I H L
Sbjct: 223 PSFVKRP-SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDD---HTLK 277
Query: 497 IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVV 556
I V D G YT V + A L ++V EPP + + VV
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASAT-LTVQVG----SEPPHFVVKPRDQ------VV 326
Query: 557 VAGNKLRLDVSITGEPPPVATWLK-GDEVFTTTEGRTRIEKRVDCSS---FVIESAQRED 612
G + TG P P W + G + + + R S I + QR D
Sbjct: 327 ALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSD 386
Query: 613 EGRYTIKVTNPVGEDVASIFLQVVDV--PDPPEAVRITSVGEDWAILVWEPPMYDGGKPV 670
G Y + N G + +L+V DV PP +R V + A+ G V
Sbjct: 387 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAV---------DGTFV 437
Query: 671 TGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG-----VSQPS 725
+ + W K V T+ + K +E + ++R + G S PS
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDS--RIKQLENGVLQIRYAKLGDTGRYTCIASTPS 495
Query: 726 MNTK------------PFMPIAPT------SEPLHLIVEDVTDTTTTLKWRPPNRIGAGG 767
P P PT S P V DV+ T TL W+P GA
Sbjct: 496 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 555
Query: 768 IDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQ 827
Y++E S E V+ +K L A LF V N G S+P+ ++
Sbjct: 556 -TSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 614
Query: 828 PVTIREI 834
PV +++
Sbjct: 615 PVKTQDV 621
Score = 66.6 bits (161), Expect = 1e-10
Identities = 134/619 (21%), Positives = 216/619 (34%), Gaps = 74/619 (11%)
Query: 441 VLQDIADLTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGR-------F 492
+++ +DL V E A C+ T +WYK G V K SH F
Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFF 90
Query: 493 HKLVIDDVRPEDEGDYTFVPDGY---ALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKT 549
++V DEG Y V Y A+S +A L ++ ++ +Q P
Sbjct: 91 LRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF--RQNP----------- 137
Query: 550 SENAIVVVAGNKLRLDVSIT-GEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESA 608
+ ++V G ++ G P P +W K + R I +I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMITYT 191
Query: 609 QREDEGRYTIKVTNPVGEDVASIF-LQVVDVPD---PPEAVRITSVGEDWAILVWEPPMY 664
++ D G+Y TN VGE + + L V++ P P + +T +D A E
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEAR-- 247
Query: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
G PV R +K K +E+ + T + K+ G + A N +G ++
Sbjct: 248 --GDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEA 302
Query: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWV 784
S + + SEP H +V+ D L + A G + + EGS+ +
Sbjct: 303 SAT----LTVQVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 785 PANTEPVERCGFTVKNLPTGARILFRV----VGVNIAGRSEPATLAQPVTIREIAEPPKI 840
+ P F+V TG + V VG I A E+ +
Sbjct: 358 FSYQPPQSSSRFSVSQ--TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD 415
Query: 841 RLPRHLRQTYIRK---VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVF 897
R P +RQ + + V L G P P ++W K G + T ++ + + V
Sbjct: 416 RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE-NGVL 474
Query: 898 FVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP---------------PINVMVK 942
+R A D+G Y + + T + I V E P P V
Sbjct: 475 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVT 534
Query: 943 EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEY 1002
+V + WQ + G + + W V E + + + L Y
Sbjct: 535 DVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIY 594
Query: 1003 YFRVYTENICGLSDSPGVS 1021
F V N G+SD +S
Sbjct: 595 LFLVRAANAYGISDPSQIS 613
Score = 57.0 bits (136), Expect = 1e-07
Identities = 77/325 (23%), Positives = 128/325 (39%), Gaps = 52/325 (16%)
Query: 831 IREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS----RV 886
+R+ PP R+ H + K GE L +G+P P + W KGG ++T R
Sbjct: 22 LRQEDFPP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 887 HVRTSDFDTVFFVR----QAARSDSGEYELSVQI---ENMKDTATIRIRVVEK--AGPPI 937
H ++FF+R + +R D G Y + E + A++ + ++ P
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPS 138
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI 997
+VMV G A++E Q P+ I K D ++ +++ + L+
Sbjct: 139 DVMVAV--GEPAVMECQPPRGHPEPTISW----KKDGSPLD-----DKDERITIRGGKLM 187
Query: 998 VGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITF---KPFEYKEHDFRMAPKFLTPL 1054
+ YT + + + G + E E P F+
Sbjct: 188 I-------TYTRK-----------SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP 229
Query: 1055 IDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFD 1114
+ V SA C RG P P V W K+ E+ + + ++ TL IR+ + D
Sbjct: 230 SNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDH----TLKIRKVTAGD 285
Query: 1115 AGTYTCRAVNELGEALAECKLEVRV 1139
G+YTC A N +G+A A L V+V
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQV 310
Score = 52.8 bits (125), Expect = 2e-06
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 79/305 (25%)
Query: 863 PFQGKPRPQVVWTKGGAPLDTS--RVHVRTSDFDTVFFVRQAARSDSGEYE-LSVQIENM 919
P +G P P + W K G+PLD R+ +R + +SD+G+Y + +
Sbjct: 154 PPRGHPEPTISWKKDGSPLDDKDERITIRGGKL----MITYTRKSDAGKYVCVGTNMVGE 209
Query: 920 KDTATIRIRVVEKAG---PPINVMVK---------EVWGTNA-LVEWQAPKDDGNSEIMG 966
+++ + V+E+ P N+ V E G V W+ KDDG
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR--KDDGELPKSR 267
Query: 967 YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
Y + R+ HT + + G+ + EN+ G +++
Sbjct: 268 YEI---------------RDDHT-LKIRKVTAGDMGSYTCVAENMVGKAEASAT------ 305
Query: 1027 ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKM 1086
L + +P P F+ D+VV G + C G+P+P + W
Sbjct: 306 -LTVQVGSEP-----------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR---- 349
Query: 1087 EIREDPKFLITNYQ-------------GVLTL-NIRRPSPFDAGTYTCRAVNELGEALAE 1132
RE + L+ +YQ G LT+ N++R D G Y C+ +N G + +
Sbjct: 350 --REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRS---DVGYYICQTLNVAGSIITK 404
Query: 1133 CKLEV 1137
LEV
Sbjct: 405 AYLEV 409
Score = 50.8 bits (120), Expect = 7e-06
Identities = 71/335 (21%), Positives = 117/335 (34%), Gaps = 37/335 (11%)
Query: 812 VGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871
VG N+ G E ++ + + P ++ P +L T V + +G P P
Sbjct: 202 VGTNMVGERE----SEVAELTVLERPSFVKRPSNLAVT----VDDSAEFKCEARGDPVPT 253
Query: 872 VVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
V W K L SR +R D +R+ D G Y + K A+ + V
Sbjct: 254 VRWRKDDGELPKSRYEIRD---DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV 310
Query: 932 KAGPPINVMVK---EVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
+ PP + +VK +V V +Q + + + + + +R
Sbjct: 311 GSEPP-HFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 369
Query: 989 TSCTVSDLIVGNEY-----YFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHD 1043
+ DL + N Y+ T N+ G + + T I
Sbjct: 370 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-------------- 415
Query: 1044 FRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL 1103
R P +++ V + L+C G P P ++W K+ + + + GV
Sbjct: 416 -RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV- 473
Query: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
L IR D G YTC A GEA +EV+
Sbjct: 474 -LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 99.0 bits (245), Expect = 2e-20
Identities = 143/611 (23%), Positives = 228/611 (37%), Gaps = 83/611 (13%)
Query: 245 LKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYV- 303
L +A++ V+ A+ + R I V I P ++KW+KN + + + V
Sbjct: 494 LYQARINVRGPASIRPMKNITAIAGRDTYIHCRV-IGYPYYSIKWYKNSNLLPFNHRQVA 552
Query: 304 FENVGKKRILTINKCTLADDAAYEVAVKDEKCFTE---LFVKEPPVLIVTPLEDQQVFVG 360
FEN G ++ + K + V V+ + ++ + VK PP + P E + +G
Sbjct: 553 FENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPP--FIQPFEFPRFSIG 610
Query: 361 DRVEMAVEV--SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGR 418
RV + V + + W KDG R L S++ G
Sbjct: 611 QRVFIPCVVVSGDLPITITWQKDG----RPIPGSLGVTIDNIDFTSSLRISNLSLMHNGN 666
Query: 419 YQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQ-------AVFKCEVSDEKV-TGK 470
Y I EA + + QL +++ V+ +Q + C V T
Sbjct: 667 YTCIARN---EAAAVEHQSQL-IVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIV 722
Query: 471 W-YKNGVEVRPSKRITISHVGRFH-----KLVIDDVRPEDEGDYTFVPDGYALSLSAKLN 524
W + G V + I ++ GR L+I V ED G Y + +K
Sbjct: 723 WKFSKGAGVPQFQPIALN--GRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSM 780
Query: 525 FLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEV 584
+L +K+ + P N + G K + + GE P + W K D +
Sbjct: 781 YLTVKIPAMITSYP-------------NTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRI 827
Query: 585 FTTTEGRTRIEKRVDCSSFVIESAQ-----REDEGRYTIKVTNPVGEDVASIFLQVVDVP 639
R + + + VI + Q RED G ++ N GED I L V + P
Sbjct: 828 INPEMARYLVSTK-EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 886
Query: 640 DPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYE 699
DPPE + I V L W +DG P+TGY +E K K S W
Sbjct: 887 DPPE-IEIKDVKARTITLRWTMG-FDGNSPITGYDIECKNK-SDSWDSAQRTKDVSPQLN 943
Query: 700 STKMIE---GILYEMRVFAVNAIGVSQPSMN-TKPFMPIAPTSEPLHLIVEDVTDTTTTL 755
S +I+ Y +R++A N IG S+PS T AP P + +E ++ + +
Sbjct: 944 SATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRV 1003
Query: 756 KWRPPNR-IGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGV 814
W+ P + + G I GY + Y + TG F ++ V
Sbjct: 1004 TWKAPKKHLQNGIIRGYQIGY-----------------------REYSTGGNFQFNIISV 1040
Query: 815 NIAGRSEPATL 825
+ +G SE TL
Sbjct: 1041 DTSGDSEVYTL 1051
Score = 59.7 bits (143), Expect = 2e-08
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 9/160 (5%)
Query: 564 LDVSITGEPPPVATWLK---GDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
L G+P P W+K G T +GR I SF+I + + ED G Y+
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSN---GSFIIRTVKAEDSGYYSCIA 1361
Query: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
N G D + LQV PD P + ++ L W P +GG + GY+++ +
Sbjct: 1362 NNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSWLPG-DNGGSSIRGYILQYSED 1419
Query: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG 720
S++W +E +Y + G Y+ + A N +G
Sbjct: 1420 NSEQWGSFPISP-SERSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
AP L R +AG L C GHP+P W+K+ M + +F T G+L N
Sbjct: 224 APSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKT-VTGLLIEN 282
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
IR P D+G+Y C N G A +L V+ P
Sbjct: 283 IR---PSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313
Score = 50.4 bits (119), Expect = 9e-06
Identities = 59/263 (22%), Positives = 102/263 (38%), Gaps = 15/263 (5%)
Query: 755 LKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGV 814
+ W PP ++ G I Y V +C + + + + NL + VV V
Sbjct: 1207 VSWLPPLKLN-GIIRKYTV-FCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAV 1264
Query: 815 NIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ--GKPRPQV 872
AGR + + +T+ +A+ P R L + ++V+P + G P P V
Sbjct: 1265 TSAGRGNSSEI---ITVEPLAKAPA----RILTFSGTVTTPWMKDIVLPCKAVGDPSPAV 1317
Query: 873 VWTK--GGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVV 930
W K G P + R+ + F +R DSG Y D + ++V
Sbjct: 1318 KWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQ 1377
Query: 931 EKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTS 990
P + V + ++ + W P D+G S I GY +Q ++ + +W + S
Sbjct: 1378 VPPDQP-RLTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERS 1435
Query: 991 CTVSDLIVGNEYYFRVYTENICG 1013
+ +L G Y F + +N G
Sbjct: 1436 YRLENLKCGTWYKFTLTAQNGVG 1458
Score = 48.5 bits (114), Expect = 4e-05
Identities = 63/297 (21%), Positives = 104/297 (35%), Gaps = 42/297 (14%)
Query: 855 GEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSV 914
G+++ L G P P W K PL+ S +T T + SDSG Y
Sbjct: 239 GQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTV---TGLLIENIRPSDSGSYVC-- 293
Query: 915 QIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADK 974
++ N TA + R+ K + ++V G+ + V +
Sbjct: 294 EVSNRYGTAKVIGRLYVKQPLKATISPRKV-----------KSSVGSQVSLSCSVTGTED 342
Query: 975 KTMEWF------NVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL 1028
+ + W+ N + R T +LI+ + D +L
Sbjct: 343 QELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVL 402
Query: 1029 KTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEI 1088
+ G PK ++ ++VV +L C V+G P P + W + I
Sbjct: 403 EDG---------------TPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPI 447
Query: 1089 REDPKF----LITNYQGVLT-LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
+ +IT+ V++ LNI D G Y C A N G L + ++ VR P
Sbjct: 448 LKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP 504
Score = 48.1 bits (113), Expect = 5e-05
Identities = 80/361 (22%), Positives = 131/361 (36%), Gaps = 49/361 (13%)
Query: 287 LKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFT--------- 337
+ W K+ + S+++ + G I + +D Y +T
Sbjct: 158 VSWEKDTVSLVSGSRFLITSTGALYIKDVQN----EDGLYNYRCITRHRYTGETRQSNSA 213
Query: 338 ELFVKEPP---VLIVTPLEDQQVFVGDRVEMAVE-VSEEGAQVMWMKDGVELTREDSFKA 393
LFV +P I+ + ++ G RVE+ + + W+KD + L
Sbjct: 214 RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPL----ELSG 269
Query: 394 RYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQ-DIADLTVKA 452
R++ G L+ ++ D G Y + A++I + L+ I+ VK+
Sbjct: 270 RFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKS 325
Query: 453 S--EQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
S Q C V+ E WY+NG + P K + I+ + L++D + D G Y
Sbjct: 326 SVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINH-ENLIMDHMVKSDGGAYQ 384
Query: 510 FVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSIT 569
LS + V+ V + PKI S K VV + L ++
Sbjct: 385 CFVRKDKLS-------AQDYVQVVLEDGTPKIISAFSEK------VVSPAEPVSLMCNVK 431
Query: 570 GEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV-----IESAQREDEGRYTIKVTNPV 624
G P P TW D+ G RI + + V I S+Q D G Y N
Sbjct: 432 GTPLPTITWTLDDDPI-LKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSA 490
Query: 625 G 625
G
Sbjct: 491 G 491
Score = 42.7 bits (99), Expect = 0.002
Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
Query: 1045 RMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVL- 1103
R+ PKF+ D+ + G + LNC+ G+P P +VW +K P+F G +
Sbjct: 687 RVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKG--AGVPQFQPIALNGRIQ 744
Query: 1104 -----TLNIRRPSPFDAGTYTCRAVNELGEALAECK-LEVRVP 1140
+L I+ D+G Y C+ N++G +++ L V++P
Sbjct: 745 VLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 787
Score = 42.4 bits (98), Expect = 0.003
Identities = 50/256 (19%), Positives = 109/256 (42%), Gaps = 26/256 (10%)
Query: 271 GNKIKLMVEISDP-DLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVA 329
G+++ L ++ D L W++NG+ + P + + ++ ++ +D AY+
Sbjct: 328 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLI-MDHMVKSDGGAYQCF 386
Query: 330 VKDEKC----FTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEG-AQVMWMKDGVE 384
V+ +K + ++ +++ I++ ++ V + V + V + W D
Sbjct: 387 VRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDP 446
Query: 385 LTREDSFKARYRFKKDGK--RHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEV- 441
+ + S + +G ++ I S V+ D G Y+ N A +++ + ++ V
Sbjct: 447 ILKGGSHRISQMITSEGNVVSYLNISSSQVR-DGGVYRCTANN---SAGVVLYQARINVR 502
Query: 442 ----LQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEVRP--SKRITISHVGRFHK 494
++ + ++T A C V KWYKN + P +++ + G
Sbjct: 503 GPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNS-NLLPFNHRQVAFENNG---T 558
Query: 495 LVIDDVRPE-DEGDYT 509
L + DV+ E DEG+YT
Sbjct: 559 LKLSDVQKEVDEGEYT 574
Score = 39.3 bits (90), Expect = 0.022
Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
R DSG + +D I++ V E PP + +K+V + W D GNS
Sbjct: 857 REDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-EIEIKDVKARTITLRWTMGFD-GNSP 914
Query: 964 IMGYFVQKADKKTMEWFNVYERN----RHTSCTVSDLIVGNEYYFRVYTENICGLSD 1016
I GY ++ K+ W + + S T+ D+ + Y R+Y +N G S+
Sbjct: 915 ITGYDIE-CKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSE 970
Score = 35.8 bits (81), Expect = 0.24
Identities = 58/306 (18%), Positives = 108/306 (35%), Gaps = 53/306 (17%)
Query: 834 IAEPPKIRL-PRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSD 892
+ +P K + PR ++ + VG Q++L G ++ W + G L+ + T
Sbjct: 310 VKQPLKATISPRKVKSS----VGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGI 365
Query: 893 FDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGP---------------PI 937
+ +SD G Y+ V+ + + +++ V+E P P+
Sbjct: 366 NHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQV-VLEDGTPKIISAFSEKVVSPAEPV 424
Query: 938 NVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLI 997
++M + W D + K + E N + +S
Sbjct: 425 SLMCNVKGTPLPTITWTLDDDP---------ILKGGSHRISQMITSEGNVVSYLNISSSQ 475
Query: 998 VGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDR 1057
V + +R C ++S GV ARI G P + P+ +
Sbjct: 476 VRDGGVYR------CTANNSAGVVLYQARINVRG----------------PASIRPMKNI 513
Query: 1058 VVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGT 1117
+AG ++C V G+P + W KN + + + + G L L+ + D G
Sbjct: 514 TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQ-KEVDEGE 572
Query: 1118 YTCRAV 1123
YTC +
Sbjct: 573 YTCNVL 578
Score = 33.1 bits (74), Expect = 1.5
Identities = 70/335 (20%), Positives = 121/335 (36%), Gaps = 65/335 (19%)
Query: 422 ITNGGQCEAELIVEEKQL-----EVLQDIADLTVKASEQAVFKCE-VSDEKVTGKWYK-- 473
+T+ G+ + I+ + L +L +T + V C+ V D KW K
Sbjct: 1264 VTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDS 1323
Query: 474 NGVE--VRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVE 531
NG V R +I G F +I V+ ED G Y+ + + S LN L+++V
Sbjct: 1324 NGTPSLVTIDGRRSIFSNGSF---IIRTVKAEDSGYYSCIANNNWGSDEIILN-LQVQV- 1378
Query: 532 YVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEG- 590
P +P RL VS T +WL GD ++ G
Sbjct: 1379 --PPDQP------------------------RLTVSKTTSSSITLSWLPGDNGGSSIRGY 1412
Query: 591 --RTRIEKRVDCSSFVIESAQREDE---------GRYTIKVTNPVGEDVASIFLQVVDVP 639
+ + SF I ++R ++T+ N VG S ++ +
Sbjct: 1413 ILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLG 1472
Query: 640 DPPEAVR-------ITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEV 692
P+ + I + ++ W DGG P+T + +E + G+ W
Sbjct: 1473 KEPQFSKEQELFASINTTRVRLNLIGWN----DGGCPITSFTLEYRPFGTTVWTTAQ-RT 1527
Query: 693 FTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMN 727
+Y + E YE+++ N+ G ++ N
Sbjct: 1528 SLSKSYILYDLQEATWYELQMRVCNSAGCAEKQAN 1562
Score = 32.7 bits (73), Expect = 2.0
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 1/94 (1%)
Query: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKP-KVVWMKNKMEIREDPKFLITNYQGVLTLN 1106
P F+ P G + C V P + W K+ I I N +L
Sbjct: 596 PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLR 655
Query: 1107 IRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140
I S G YTC A NE + +L VRVP
Sbjct: 656 ISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Score = 32.3 bits (72), Expect = 2.6
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 1067 LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLN----IRRPSPFDAGTYTCRA 1122
L C G P P V WMK+ P + + + + N IR D+G Y+C A
Sbjct: 1305 LPCKAVGDPSPAVKWMKDS---NGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 1123 VNELGEALAECKLEVRVP 1140
N G L+V+VP
Sbjct: 1362 NNNWGSDEIILNLQVQVP 1379
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,753,028
Number of Sequences: 37866
Number of extensions: 2302017
Number of successful extensions: 22142
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 329
Number of HSP's that attempted gapping in prelim test: 11490
Number of HSP's gapped (non-prelim): 5629
length of query: 1141
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1028
effective length of database: 13,968,660
effective search space: 14359782480
effective search space used: 14359782480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.