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Search of human proteins with 13376818
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
(335 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 644 0.0
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 644 0.0
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 120 1e-27
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 120 1e-27
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 120 1e-27
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 99 7e-21
gi|187607364 tuftelin 1 isoform 2 [Homo sapiens] 71 1e-12
gi|9910596 tuftelin 1 isoform 1 [Homo sapiens] 71 1e-12
gi|55770834 centromere protein F [Homo sapiens] 68 1e-11
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 65 9e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 65 1e-10
gi|118498362 kinectin 1 isoform b [Homo sapiens] 64 2e-10
gi|71061468 centromere protein E [Homo sapiens] 62 6e-10
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 62 7e-10
gi|118498356 kinectin 1 isoform a [Homo sapiens] 61 2e-09
gi|33620775 kinectin 1 isoform a [Homo sapiens] 61 2e-09
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 61 2e-09
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 60 2e-09
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 60 2e-09
gi|7705415 hook homolog 1 [Homo sapiens] 60 3e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 59 5e-09
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 59 6e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 6e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 6e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 6e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 6e-09
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 59 6e-09
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H... 59 6e-09
gi|55749696 outer dense fiber of sperm tails 2-like isoform a [H... 59 6e-09
gi|58530840 desmoplakin isoform I [Homo sapiens] 59 8e-09
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 644 bits (1661), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS 60
MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS
Sbjct: 1 MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS 60
Query: 61 TNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR 120
TNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR
Sbjct: 61 TNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR 120
Query: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK 180
EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK
Sbjct: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK 180
Query: 181 LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ 240
LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ
Sbjct: 181 LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ 240
Query: 241 EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA 300
EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA
Sbjct: 241 EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA 300
Query: 301 LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK 335
LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK
Sbjct: 301 LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK 335
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 644 bits (1661), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS 60
MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS
Sbjct: 1 MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS 60
Query: 61 TNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR 120
TNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR
Sbjct: 61 TNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR 120
Query: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK 180
EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK
Sbjct: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK 180
Query: 181 LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ 240
LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ
Sbjct: 181 LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ 240
Query: 241 EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA 300
EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA
Sbjct: 241 EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA 300
Query: 301 LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK 335
LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK
Sbjct: 301 LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK 335
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 120 bits (302), Expect = 1e-27
Identities = 93/333 (27%), Positives = 168/333 (50%), Gaps = 55/333 (16%)
Query: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKD--EIRHD--------STNHK------- 64
+Y +++ + EE Y+K +R TL+K+R +M+ D E+R S +H
Sbjct: 89 VYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLEN 148
Query: 65 --------LDAKHCGNLQQGSDS-------------------EMDPSCCSLDLLMKKIKG 97
LD + N SDS ++ + + M K++
Sbjct: 149 HIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLRE 208
Query: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
K QL EN++LK+K+++S+EA A +R + ++L+ Y+ + +E ++K K+ L
Sbjct: 209 KQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL- 267
Query: 158 VNKLEKEQKLKQHVENLN---QVAE-KLEEKHSQITELENLVQRMEKEKRTLLERKLSLE 213
LE+ + +E N Q AE LEEK +I EL+ L++RMEKE+ L + L E
Sbjct: 268 ---LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE 324
Query: 214 NKLL-QLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLK 272
++ +L S + Q L+ + L+E+I HL ++H Q + ++ +++E+E LK L+
Sbjct: 325 TEMSGELTDSDK--ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQ 382
Query: 273 EQDKRIENLREKVNILEAQNKELKTQVALSSET 305
++ I L EK++ LE +N EL++++ +ET
Sbjct: 383 QKQLLILQLLEKISFLEGENNELQSRLDYLTET 415
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 120 bits (302), Expect = 1e-27
Identities = 93/333 (27%), Positives = 168/333 (50%), Gaps = 55/333 (16%)
Query: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKD--EIRHD--------STNHK------- 64
+Y +++ + EE Y+K +R TL+K+R +M+ D E+R S +H
Sbjct: 89 VYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLEN 148
Query: 65 --------LDAKHCGNLQQGSDS-------------------EMDPSCCSLDLLMKKIKG 97
LD + N SDS ++ + + M K++
Sbjct: 149 HIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLRE 208
Query: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
K QL EN++LK+K+++S+EA A +R + ++L+ Y+ + +E ++K K+ L
Sbjct: 209 KQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL- 267
Query: 158 VNKLEKEQKLKQHVENLN---QVAE-KLEEKHSQITELENLVQRMEKEKRTLLERKLSLE 213
LE+ + +E N Q AE LEEK +I EL+ L++RMEKE+ L + L E
Sbjct: 268 ---LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE 324
Query: 214 NKLL-QLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLK 272
++ +L S + Q L+ + L+E+I HL ++H Q + ++ +++E+E LK L+
Sbjct: 325 TEMSGELTDSDK--ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQ 382
Query: 273 EQDKRIENLREKVNILEAQNKELKTQVALSSET 305
++ I L EK++ LE +N EL++++ +ET
Sbjct: 383 QKQLLILQLLEKISFLEGENNELQSRLDYLTET 415
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 120 bits (302), Expect = 1e-27
Identities = 93/333 (27%), Positives = 168/333 (50%), Gaps = 55/333 (16%)
Query: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKD--EIRHD--------STNHK------- 64
+Y +++ + EE Y+K +R TL+K+R +M+ D E+R S +H
Sbjct: 89 VYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLEN 148
Query: 65 --------LDAKHCGNLQQGSDS-------------------EMDPSCCSLDLLMKKIKG 97
LD + N SDS ++ + + M K++
Sbjct: 149 HIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLRE 208
Query: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
K QL EN++LK+K+++S+EA A +R + ++L+ Y+ + +E ++K K+ L
Sbjct: 209 KQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL- 267
Query: 158 VNKLEKEQKLKQHVENLN---QVAE-KLEEKHSQITELENLVQRMEKEKRTLLERKLSLE 213
LE+ + +E N Q AE LEEK +I EL+ L++RMEKE+ L + L E
Sbjct: 268 ---LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE 324
Query: 214 NKLL-QLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLK 272
++ +L S + Q L+ + L+E+I HL ++H Q + ++ +++E+E LK L+
Sbjct: 325 TEMSGELTDSDK--ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQ 382
Query: 273 EQDKRIENLREKVNILEAQNKELKTQVALSSET 305
++ I L EK++ LE +N EL++++ +ET
Sbjct: 383 QKQLLILQLLEKISFLEGENNELQSRLDYLTET 415
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 98.6 bits (244), Expect = 7e-21
Identities = 91/338 (26%), Positives = 161/338 (47%), Gaps = 63/338 (18%)
Query: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKD--EIRHD--------STNHK------- 64
+Y +++ + EE Y+K +R TL+K+R +M+ D E+R S +H
Sbjct: 89 VYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLEN 148
Query: 65 --------LDAKHCGNLQQGSDS-------------------EMDPSCCSLDLLMKKIKG 97
LD + N SDS ++ + + M K++
Sbjct: 149 HIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLRE 208
Query: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
K QL EN++LK+K+++S+EA A +R + ++L+ Y+ + +E ++K K+ L
Sbjct: 209 KQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL- 267
Query: 158 VNKLEKEQKLKQHVENLN---QVAE-KLEEKHSQITELENLVQRMEKEKRTLLERKLSLE 213
LE+ + +E N Q AE LEEK +I EL+ L++RMEKE+ L + L E
Sbjct: 268 ---LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE 324
Query: 214 NKLL-QLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLK 272
++ +L S + Q L+ + L+E+I HL ++H Q + ++ +++E NN
Sbjct: 325 TEMSGELTDSDK--ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEE-----NN-- 375
Query: 273 EQDKRIENLREKVNILEAQNKELKTQV-ALSSETPRTK 309
E R++ L E E + +E+ L S+T RT+
Sbjct: 376 ELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTR 413
>gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
Length = 365
Score = 71.2 bits (173), Expect = 1e-12
Identities = 61/281 (21%), Positives = 129/281 (45%), Gaps = 38/281 (13%)
Query: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEM 81
++E + E +Y+++ R LQK+R + + KLD +L +
Sbjct: 66 IHEKNINQLKSEVQYIQEARNCLQKLR----------EDISSKLDRNLGDSLHRQ----- 110
Query: 82 DPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQ 141
+ ++++K G + + + E +LR Q L Q
Sbjct: 111 -----EIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVE----SLRKTVQDLLAKLQ-- 159
Query: 142 SEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKE 201
E +++ + +V +++ +Q L + +++E+K +++ EL+ + ME E
Sbjct: 160 --EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 217
Query: 202 KRTLLERKLSLENKLLQLKSSATYGKSCQ-------DLQREISILQEQISHLQFVIHSQH 254
+ LL + E L +L+S+ CQ L++E++ L+E+I HL ++ SQ
Sbjct: 218 HQALLAKVREGEVALEELRSN---NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 274
Query: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL 295
+ +R +I++++ K ++ +D I+ L+EK+ LEA+N E+
Sbjct: 275 RKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 315
>gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
Length = 390
Score = 71.2 bits (173), Expect = 1e-12
Identities = 61/281 (21%), Positives = 129/281 (45%), Gaps = 38/281 (13%)
Query: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEM 81
++E + E +Y+++ R LQK+R + + KLD +L +
Sbjct: 91 IHEKNINQLKSEVQYIQEARNCLQKLR----------EDISSKLDRNLGDSLHRQ----- 135
Query: 82 DPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQ 141
+ ++++K G + + + E +LR Q L Q
Sbjct: 136 -----EIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVE----SLRKTVQDLLAKLQ-- 184
Query: 142 SEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKE 201
E +++ + +V +++ +Q L + +++E+K +++ EL+ + ME E
Sbjct: 185 --EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 242
Query: 202 KRTLLERKLSLENKLLQLKSSATYGKSCQ-------DLQREISILQEQISHLQFVIHSQH 254
+ LL + E L +L+S+ CQ L++E++ L+E+I HL ++ SQ
Sbjct: 243 HQALLAKVREGEVALEELRSN---NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 299
Query: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL 295
+ +R +I++++ K ++ +D I+ L+EK+ LEA+N E+
Sbjct: 300 RKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 340
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 68.2 bits (165), Expect = 1e-11
Identities = 77/311 (24%), Positives = 132/311 (42%), Gaps = 29/311 (9%)
Query: 16 MEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQ 75
++D + +S+ ++ E E K + + + +M E H++ A+ LQ+
Sbjct: 2579 LQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEM-AQKTAELQE 2637
Query: 76 GSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLF 135
E + L LL+++IK QL E+ EN LK L + V + +
Sbjct: 2638 ELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIA 2697
Query: 136 ENYQTQSEEVRKKQE----DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITEL 191
E YQ + E KK + D+ + +V +KL E L+ +++ S EL
Sbjct: 2698 E-YQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEEL 2756
Query: 192 EN----LVQRMEKEKRTLLE-----RKLSLENKLLQLKSSATYGKSCQDLQREISILQEQ 242
N Q +E+ K+T ++ +L EN+ Q K KSC+ L+ E ILQ++
Sbjct: 2757 NNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLI-KSCKQLEEEKEILQKE 2815
Query: 243 ISHLQFVIHSQ------HQNLRSVIQEMEGLKNNLKEQDKRIENLREKV-------NILE 289
+S LQ Q + + E++ LK L+E+ K + +K LE
Sbjct: 2816 LSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLE 2875
Query: 290 AQNKELKTQVA 300
+ L+TQVA
Sbjct: 2876 KAKEMLETQVA 2886
Score = 55.1 bits (131), Expect = 9e-08
Identities = 68/336 (20%), Positives = 149/336 (44%), Gaps = 23/336 (6%)
Query: 13 RDKMEDNSALYESTSAHIIEETEYVKKIRTTL--QKIRTQMFKDEIRHDSTNHKLDAKHC 70
RD++ +A Y+ S + +KK+ L Q+ + + + + + +
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEE 399
Query: 71 GNLQQGSDSEMDPSCCSLD--LLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR 128
+ QQ S +D C + L + + K++ + + +++ +K Q +
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 129 NV-AQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQ--HVENLNQVAEKLEEKH 185
A++ F+ Q + E+R+ E+ K+ + K EQK ++ H+E +L+
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLE------AELKNIK 513
Query: 186 SQITELENLVQRMEKEKRTLLERKL-SLENKLLQLKSSATYGK---SCQDLQREISILQE 241
+ + +N + M K K T E L L+ K+ Q ++S T K + DL+++ Q+
Sbjct: 514 QCLNQSQNFAEEM-KAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQD 572
Query: 242 QISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNIL---EAQNKELKTQ 298
+ + I + L +E + L + L+ + K E L+E+ + +++N++L TQ
Sbjct: 573 LLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQ 632
Query: 299 VALSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLR 334
+ E ++K++ + LKT+ + + R+R
Sbjct: 633 MESEKENLQSKINHLETC--LKTQQIKSHEYNERVR 666
Score = 52.0 bits (123), Expect = 7e-07
Identities = 53/288 (18%), Positives = 127/288 (44%), Gaps = 22/288 (7%)
Query: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKL-DAKHCGNLQQGSDSE 80
+ ++T + E ++R +++K+R ++ DE + +L +++H +L +G
Sbjct: 2281 IMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVEN 2340
Query: 81 MDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR------EAGAAALRNVAQRL 134
++ L++ + L+ E E LK K++ E +R+ + L
Sbjct: 2341 LERE---LEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENL 2397
Query: 135 FENYQTQSEEVRKKQ---EDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITEL 191
Q + E + + + + +LQ + EK Q ++ + + +L+E + ++ L
Sbjct: 2398 TNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAAL 2457
Query: 192 ENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIH 251
N ++E E+ LS + + L+L+ + + + + +LQ ++ L +
Sbjct: 2458 HN-----DQEACKAKEQNLSSQVECLELEKAQLL-QGLDEAKNNYIVLQSSVNGLIQEVE 2511
Query: 252 SQHQNLRSVIQEMEGLKNNLKEQDKRIENLRE---KVNILEAQNKELK 296
Q L +E+ LKN +++Q++ + L + + + + QN EL+
Sbjct: 2512 DGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELR 2559
Score = 48.9 bits (115), Expect = 6e-06
Identities = 62/263 (23%), Positives = 122/263 (46%), Gaps = 51/263 (19%)
Query: 35 EYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKK 94
E V ++R ++K+R ++ DE + KL + N D L K
Sbjct: 2112 EEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKEREREN----------------DSLKDK 2155
Query: 95 IKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQ 154
++ + +L +M++EN+ L I L A EN + + E ++ + E+ +
Sbjct: 2156 VENLEREL-QMSEENQELVI-LDA-----------------ENSKAEVETLKTQIEEMAR 2196
Query: 155 LLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLEN 214
L+V +L+ L+ ENL + +++EK Q++EL+ L+ ++LLE K E
Sbjct: 2197 SLKVFELDLVT-LRSEKENLTK---QIQEKQGQLSELDKLLSSF----KSLLEEKEQAEI 2248
Query: 215 KLLQLKSSATYGKSCQDLQREISILQEQISHL---QFVIHSQHQNLRSVIQEMEGLKNNL 271
++ + +A + LQ ++ L E ++ L Q ++ + Q+L I+E L+N++
Sbjct: 2249 QIKEESKTAV-----EMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSI 2303
Query: 272 KEQDKRIENLREKVNILEAQNKE 294
++ R+E +K + Q KE
Sbjct: 2304 EKLRARLEADEKKQLCVLQQLKE 2326
Score = 48.1 bits (113), Expect = 1e-05
Identities = 51/235 (21%), Positives = 102/235 (43%), Gaps = 37/235 (15%)
Query: 133 RLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELE 192
+L E + +++E+ Q + +QV + E ++K + + V+E L++K T L+
Sbjct: 1979 QLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDK----THLQ 2034
Query: 193 NLVQRMEKEKRTLLERKLSLENKLLQL-KSSATYGKSCQDLQR----------------- 234
+Q +EK+ + L K LEN++ QL K K + LQ
Sbjct: 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALE 2094
Query: 235 -----------EISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLRE 283
+S QE++ L+ I + + ++ + LKE+++ ++L++
Sbjct: 2095 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKD 2154
Query: 284 KVNILEAQ---NKELKTQVALSSETPRTKVSKAVSTSELKTEGVSPY-LMLIRLR 334
KV LE + ++E + V L +E + +V + E + + L L+ LR
Sbjct: 2155 KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Score = 48.1 bits (113), Expect = 1e-05
Identities = 55/245 (22%), Positives = 116/245 (47%), Gaps = 27/245 (11%)
Query: 96 KGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQL 155
K ++L+L + E E KI++ S+ A V Q ++N + + E K + +
Sbjct: 2552 KEQNLELRNLTVELEQ-KIQVLQSKNASLQDTLEVLQSSYKNLENELELT--KMDKMSFV 2608
Query: 156 LQVNKLE-KEQKLKQHVENLNQVAEKLEE-----KHSQITELENLVQRMEKEKRTLLERK 209
+VNK+ KE +L++ + + Q +L+E K+ EL+ L++ ++ K L E
Sbjct: 2609 EKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKE-- 2666
Query: 210 LSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHS---QHQNL-----RSVI 261
L+LEN L+ + +D + ++E+I+ Q +H +HQ L +
Sbjct: 2667 LTLENSELKKSLDCMH----KDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYE 2722
Query: 262 QEMEGLKNNLKEQDKRIENLREKVNILEAQNKE----LKTQVALSSETPRTKVSKAVSTS 317
E++ + L +++ + + + ++++L++ +E LK + E +TK+ +
Sbjct: 2723 VEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVN 2782
Query: 318 ELKTE 322
+LK E
Sbjct: 2783 QLKKE 2787
Score = 47.0 bits (110), Expect = 2e-05
Identities = 54/236 (22%), Positives = 116/236 (49%), Gaps = 24/236 (10%)
Query: 74 QQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKEN-EVLKIKLQASREAGAAALRNVAQ 132
+Q SE++ S + ++++ + + +Q+ E + E+L+ +L+ E AAL N +
Sbjct: 2404 EQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNER-VAALHNDQE 2462
Query: 133 RLFENYQTQSEEVRKKQEDSKQLLQV------NKLEKEQKLKQHVENLNQVAEKLEEKHS 186
Q S +V + + QLLQ N + + + ++ + +KLE+K
Sbjct: 2463 ACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Query: 187 QITELENLVQRMEK--EKRTLLERKLSL-ENKLLQLKSSATYGKSCQDLQREISILQEQI 243
+I+ L+N +Q E+ K + +E + L + + L+L++ +L+++I +LQ +
Sbjct: 2523 EISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTV------ELEQKIQVLQSKN 2576
Query: 244 SHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
+ LQ + + +++ E+E L + DK + EKVN + A+ EL+ ++
Sbjct: 2577 ASLQDTLEVLQSSYKNLENELE-----LTKMDKM--SFVEKVNKMTAKETELQREM 2625
Score = 46.2 bits (108), Expect = 4e-05
Identities = 45/203 (22%), Positives = 95/203 (46%), Gaps = 16/203 (7%)
Query: 101 QLLEMNKENEVL---KIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
Q+ ++NKE E+L LQA NV++ L + E + +++ Q
Sbjct: 2057 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ 2116
Query: 158 VNKLEKEQKLKQHVENLNQ--VAEKLEEKHSQITELENLVQRMEKEKRTLLERK----LS 211
+ + ++ +++ + Q +AEKL+E+ + L++ V+ +E+E + E + L
Sbjct: 2117 LRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILD 2176
Query: 212 LENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNL 271
EN ++++ T +++ R + + + + L+ S+ +NL IQE +G + L
Sbjct: 2177 AENSKAEVETLKT---QIEEMARSLKVFELDLVTLR----SEKENLTKQIQEKQGQLSEL 2229
Query: 272 KEQDKRIENLREKVNILEAQNKE 294
+ ++L E+ E Q KE
Sbjct: 2230 DKLLSSFKSLLEEKEQAEIQIKE 2252
Score = 44.7 bits (104), Expect = 1e-04
Identities = 60/254 (23%), Positives = 117/254 (46%), Gaps = 47/254 (18%)
Query: 74 QQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKEN-EVLKIKLQASREAGAAALRNVAQ 132
+QG SE+D S L+++ + ++Q+ E +K E+L+ +L+ EA AA +
Sbjct: 2222 KQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGD--- 2278
Query: 133 RLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKH----SQI 188
+E+ K E S +E+E +L+ +E L E E+K Q+
Sbjct: 2279 ----------QEIMKATEQSLD----PPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQL 2324
Query: 189 TELEN----LVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQIS 244
E E+ L R+E +R L + + E+ L+ ++S + L+ +I + + +
Sbjct: 2325 KESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKG---EVETLKAKIEGMTQSLR 2381
Query: 245 HLQF---VIHSQHQNLRSVIQEME-----------GLKNNLKEQDKRIENLREK----VN 286
L+ I S+ +NL + +Q+ + +N L+E+++ ++EK +
Sbjct: 2382 GLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAME 2441
Query: 287 ILEAQNKELKTQVA 300
+L+ Q KEL +VA
Sbjct: 2442 MLQTQLKELNERVA 2455
Score = 43.5 bits (101), Expect = 3e-04
Identities = 69/350 (19%), Positives = 141/350 (40%), Gaps = 63/350 (18%)
Query: 14 DKMEDNSALYESTSAHIIEETEYVKKIRTTLQK-----------IRTQMFKDEIRHDSTN 62
D+ NSA+ ++ + E K++ + LQK I + K E H S
Sbjct: 819 DQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFV 878
Query: 63 HKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIK-LQASRE 121
+ ++ LQ+ + + + +L L K K+LQLL E E +I+ L+ S
Sbjct: 879 AET-SQRISKLQEDTSAHQNVVAETLSALENK--EKELQLLNDKVETEQAEIQELKKSNH 935
Query: 122 AGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKL 181
+L+ + Q SE + ++++ ++ +NK E +E L Q L
Sbjct: 936 LLEDSLKEL--------QLLSETLSLEKKEMSSIISLNKRE--------IEELTQENGTL 979
Query: 182 EEKHSQITELENLVQRMEKEKRTLLERKLSLEN-------------------KLLQLKSS 222
+E ++ + + EK L+++ S N KL+ L+
Sbjct: 980 KEINASLNQ----------EKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRC 1029
Query: 223 ATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLR 282
G + +DL ++ QE+ S L+ +++ + E+E LK K +
Sbjct: 1030 EETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFA---KEHQEFL 1086
Query: 283 EKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTEGVSPYLMLIR 332
K+ E +N+ L ++ + R++++ + S+ + G+ +M ++
Sbjct: 1087 TKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLK 1136
Score = 41.6 bits (96), Expect = 0.001
Identities = 79/360 (21%), Positives = 136/360 (37%), Gaps = 75/360 (20%)
Query: 30 IIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSE-----MDPS 84
+++E E + K+ T + + + + IR+ + + C N + D E +D
Sbjct: 1149 LLQENEQLMKVMKTKHECQN-LESEPIRNSVKERESERNQC-NFKPQMDLEVKEISLDSY 1206
Query: 85 CCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR------------EAGAAALRNVAQ 132
L L ++ K+L+L E KE E L+ +LQ R + L++
Sbjct: 1207 NAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEI 1266
Query: 133 RLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLE-EKHSQITEL 191
E Y + E+ Q D+ L Q + KL + L ++ E L+ EK+ +TEL
Sbjct: 1267 DAEEKYISGPHELSTSQNDNAHL-QCSLQTTMNKLNE----LEKICEILQAEKYELVTEL 1321
Query: 192 ENLVQRMEKEKRTLLER--KLSLENKLLQLKSSATYGKSCQDL----------------- 232
+ R + E KL E K+L S +G+ +D+
Sbjct: 1322 NDSRSECITATRKMAEEVGKLLNEVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSL 1381
Query: 233 -------------------QREISILQEQISHLQF---VIHSQHQNLRSVIQEMEGLKNN 270
Q + LQE+ LQ ++H QH + S + E++ ++
Sbjct: 1382 APLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDS 1441
Query: 271 LKEQDKRIENLREKVNILEAQNKELKTQVALSSE---TPRTKVSKAVSTSELKTEGVSPY 327
LK ENL N+ Q +L ++ L E P S +S L + G S +
Sbjct: 1442 LK-----AENLVLSTNLRNFQG-DLVKEMQLGLEEGLVPSLSSSCVPDSSSLSSLGDSSF 1495
Score = 41.2 bits (95), Expect = 0.001
Identities = 64/262 (24%), Positives = 109/262 (41%), Gaps = 39/262 (14%)
Query: 72 NLQQGSDS---EMDPSCCSLDLLMKKIKGKDLQLLEMNKEN----EVLKIKLQASREAGA 124
NL Q S+S +D S+ L + K + L LL+ +E E L K +A++E +
Sbjct: 992 NLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNS 1051
Query: 125 A--ALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLE 182
L N L EN + + E++ KE K+H E L ++A E
Sbjct: 1052 KLECLLNECTSLCENRKNELEQL-----------------KEAFAKEHQEFLTKLAFAEE 1094
Query: 183 EKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQ 242
+ + ELE + Q + E S L Q T + +Q+E++ L ++
Sbjct: 1095 RNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQ--EIMTLKEEQNKMQKEVNDLLQE 1152
Query: 243 ISHLQFVIHSQH--QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA 300
L V+ ++H QNL E E ++N++KE+ E+ R + N + E+K
Sbjct: 1153 NEQLMKVMKTKHECQNL-----ESEPIRNSVKER----ESERNQCNFKPQMDLEVKEISL 1203
Query: 301 LSSETPRTKVSKAVSTSELKTE 322
S ++ + ELK +
Sbjct: 1204 DSYNAQLVQLEAMLRNKELKLQ 1225
Score = 39.3 bits (90), Expect = 0.005
Identities = 46/190 (24%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 144 EVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKR 203
E++K+ D + L+ + Q+L Q VE + LE H+ + E++ + K
Sbjct: 1834 ELKKENSDLSEKLEYFSCD-HQELLQRVETSEGLNSDLE-MHADKSSREDIGDNVAKVND 1891
Query: 204 TLLERKLSLENKLLQLKS-------SATYGKS-CQDLQREISILQEQISHLQFVIHSQHQ 255
+ ER L +EN+L +++S A Y ++ + +Q E L++ + Q VI +
Sbjct: 1892 SWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEE 1951
Query: 256 NLRSVIQEMEGLKNNLKEQDKRI-------ENLREKVNILEAQNKELK--TQVALSSETP 306
L V E L+ L K+ E ++EK LE+ E QVA +
Sbjct: 1952 ELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKE 2011
Query: 307 RTKVSKAVST 316
+T++ + +S+
Sbjct: 2012 KTELLQTLSS 2021
Score = 38.9 bits (89), Expect = 0.007
Identities = 59/299 (19%), Positives = 126/299 (42%), Gaps = 31/299 (10%)
Query: 38 KKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKG 97
K + QK+ + + H+ + ++ +++ L LL +I
Sbjct: 689 KSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMD 748
Query: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQS----------EEVRK 147
KD +++ E E L+ L+ S++A + + L Q + E+
Sbjct: 749 KDRCYQDLHAEYESLRDLLK-SKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSM 807
Query: 148 KQEDSKQLLQVNKLEKEQKLKQH-VENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLL 206
E S+ L+ ++ K + Q+ V++L E ++ +S + +K+ L+
Sbjct: 808 PSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDL----------QKQCEELV 857
Query: 207 ERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEG 266
+ K +E L+ K+ + + + IS LQE S Q V+ L + +E++
Sbjct: 858 QIKGEIEENLM--KAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQL 915
Query: 267 LKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSET---PRTKVSKAVSTSELKTE 322
L + ++ + I+ L++ ++LE KEL+ L SET + ++S +S ++ + E
Sbjct: 916 LNDKVETEQAEIQELKKSNHLLEDSLKELQ----LLSETLSLEKKEMSSIISLNKREIE 970
Score = 33.5 bits (75), Expect = 0.27
Identities = 41/188 (21%), Positives = 79/188 (42%), Gaps = 23/188 (12%)
Query: 152 SKQLLQVNKLEKEQKLKQHVEN---LNQVAEKLEEKHSQITELENLVQRMEKEKR----T 204
S+ LQ+ K + + + L+Q+ + +E ++I ELE +Q EKE +
Sbjct: 255 SRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNK 314
Query: 205 LLERKLSLENKLLQLKSSATYGKSCQD-----------LQREISILQEQISHLQFVIHSQ 253
E +L LE ++L C+D + + L++++ L + Q
Sbjct: 315 FQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQ 374
Query: 254 HQNLRSVIQEMEGLKNNLKEQDKRI-ENLREKVNILEAQNKE-LKTQVALSSETPRTKVS 311
QN S +E +KE++K E L + + ++E ++ + L+ E + K
Sbjct: 375 RQNAESARCSLE---QKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNM 431
Query: 312 KAVSTSEL 319
V +EL
Sbjct: 432 HNVLQAEL 439
Score = 32.0 bits (71), Expect = 0.80
Identities = 30/151 (19%), Positives = 69/151 (45%), Gaps = 25/151 (16%)
Query: 157 QVNKLEKEQKLKQHVEN-----LNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLS 211
Q++KL+KE++ +Q + L + +K+E + ++ T L ++E + L+E S
Sbjct: 26 QLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNL-------KRENQRLMEICES 78
Query: 212 LENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNL 271
LE K+ Q + E+ + + Q++ + ++S + + + QE++ K+ L
Sbjct: 79 LE-------------KTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSEL 125
Query: 272 KEQDKRIENLREKVNILEAQNKELKTQVALS 302
+ + ++ +N K T + S
Sbjct: 126 ERSQQAAQSADVSLNPCNTPQKIFTTPLTPS 156
Score = 30.8 bits (68), Expect = 1.8
Identities = 36/166 (21%), Positives = 69/166 (41%), Gaps = 20/166 (12%)
Query: 149 QEDSKQL-LQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLE 207
QED L L+V + E HV + K+E +++ EL++ + E + T +E
Sbjct: 1766 QEDIHNLQLRVKETSNENLRLLHV--IEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIE 1823
Query: 208 RKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGL 267
+ LE K +L++E S L E++ + HQ L ++ EGL
Sbjct: 1824 ACIELE-------------KIVGELKKENSDLSEKLEYFS----CDHQELLQRVETSEGL 1866
Query: 268 KNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKA 313
++L+ + N+ + + + + + +E R + KA
Sbjct: 1867 NSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKA 1912
Score = 30.4 bits (67), Expect = 2.3
Identities = 41/177 (23%), Positives = 81/177 (45%), Gaps = 33/177 (18%)
Query: 150 EDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERK 209
E+ K+ L L+K Q+L+ ++ L + EK + +L++L ++K+K+ + K
Sbjct: 6 EEWKEGLPTRALQKIQELEGQLDKLKK------EKQQRQFQLDSLEAALQKQKQKVENEK 59
Query: 210 -----LSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEM 264
L EN+ L + C+ L++ +++ISH V SQ +
Sbjct: 60 TEGTNLKRENQRLM--------EICESLEKT----KQKISHELQVKESQ-------VNFQ 100
Query: 265 EGLKNNLKEQDKRIEN--LREKVNILEAQNKELKTQVALS-SETPRTKVSKAVSTSE 318
EG N+ K+Q +++E R K + +Q V+L+ TP+ + ++ S+
Sbjct: 101 EGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQ 157
Score = 30.4 bits (67), Expect = 2.3
Identities = 41/183 (22%), Positives = 80/183 (43%), Gaps = 13/183 (7%)
Query: 59 DSTNHKLDAKHCGNLQQGSDSE--MDPSCCSLD-LLMKKIKGKDLQLLEMNKENEVLKIK 115
DS+ ++ + G++ S+ E + + CS+D + ++ ++L KE K
Sbjct: 1492 DSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLT----RKETPSAPAK 1547
Query: 116 LQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLN 175
E+ R ++L E ++Q K+ ++ +QLL + E + KQ++
Sbjct: 1548 GVEELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENE 1607
Query: 176 QVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQRE 235
Q +KL S E+E+ ++ EK+ + L LE LQL+ +S + E
Sbjct: 1608 QWQQKLT---SVTLEMES---KLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTE 1661
Query: 236 ISI 238
+I
Sbjct: 1662 DAI 1664
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 65.1 bits (157), Expect = 9e-11
Identities = 73/325 (22%), Positives = 146/325 (44%), Gaps = 46/325 (14%)
Query: 6 VTTEIPPRDKMEDNSALYES---TSAHIIEETEYVKKIRTTLQKI-----RTQMFKDEIR 57
++ E +D ++N L+ES TS+ + + ++I+ L+ R + ++E+
Sbjct: 576 ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 635
Query: 58 HDSTNHKLDAKHCGNLQ---------QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKE 108
H ++L K NL+ + +SE++ L + K QL + KE
Sbjct: 636 HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 109 NEVL---KIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQ 165
N L ++L+ + E+ A +AQ EN + +SE+ + K+ K E+ +
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLE 755
Query: 166 KLKQHVENLNQVAEK-LEEKHSQITELENLVQRMEKEKRTLL----ERKLSLENKLLQLK 220
Q ++ NQ +K LE + +I +LE+ +Q +E E +TL E K+S
Sbjct: 756 VSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIS--------- 806
Query: 221 SSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN 280
K + L++E L+++ S L+ ++ + + +E + L+ + +D +E
Sbjct: 807 -----SKRLEQLEKENKSLEQETSQLE-------KDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 281 LREKVNILEAQNKELKTQVALSSET 305
K+ LE +NK L ++ + E+
Sbjct: 855 NNVKIGNLEKENKTLSKEIGIYKES 879
Score = 50.4 bits (119), Expect = 2e-06
Identities = 66/321 (20%), Positives = 134/321 (41%), Gaps = 57/321 (17%)
Query: 34 TEYVKKIRTTLQKIR---TQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDL 90
T+ V+++RTT+ + +++ K E + + K++ + Q S + S DL
Sbjct: 473 TKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE-NEIVQEKQSLQNCQNLSKDL 531
Query: 91 LMKKIK-GKDLQLLEMNKENEV----------------LKIKLQASREAGAAALRNVAQR 133
+ +K + K ++ L N E ++ L+ + Q S EA + +
Sbjct: 532 MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI 591
Query: 134 LFENYQTQSEEVRKKQEDSKQLL------------------QVNKLEKEQKLKQH-VENL 174
L E+ + S ++ K + + +Q+ +++ LEKE +L Q + NL
Sbjct: 592 LHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Query: 175 NQVAEKLEEKHSQITELE--------------NL---VQRMEKEKRTLLERKLSLENKLL 217
EK+E + +ELE NL ++ +EKE L E L L +
Sbjct: 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVE 711
Query: 218 QLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKR 277
LK ++ Q +E+ +EQ+ ++ + + + +GL + K
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKT 771
Query: 278 IENLREKVNILEAQNKELKTQ 298
+EN +K+ LE++ ++L+ +
Sbjct: 772 LENSNKKIQQLESELQDLEME 792
Score = 50.1 bits (118), Expect = 3e-06
Identities = 71/326 (21%), Positives = 153/326 (46%), Gaps = 39/326 (11%)
Query: 13 RDKMEDNSALYESTSAHII-EETEYVKKIRTTLQKIRTQMFKDEIR-HDSTNHKLDAKHC 70
R + E+ + L ++ SA + +E + +++ + K+ +++ + + R HD +K +
Sbjct: 290 RLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEE- 348
Query: 71 GNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNV 130
L++ + ++ D L + + + +L E+ KEN LK KL + +
Sbjct: 349 --LKEDNQVLLETKTMLEDQL-EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKI 405
Query: 131 AQRLFENY-----QTQS-----------EEVRKKQEDSKQLL-----QVNKLEKEQKLKQ 169
+ + EN Q QS E++ + E S+ +VN+L + LK
Sbjct: 406 EELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKL 465
Query: 170 HVEN--LNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGK 227
+EN L + E+L + + + +MEKE + L ++ LEN+++Q K S +
Sbjct: 466 EMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSL---Q 522
Query: 228 SCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNI 287
+CQ+L ++ L ++ + L+ I + +N I+ +E +L ++ + +LR++ I
Sbjct: 523 NCQNLSKD---LMKEKAQLEKTIETLRENSERQIKILEQENEHL---NQTVSSLRQRSQI 576
Query: 288 -LEAQNKELKTQVALSSETPRTKVSK 312
EA+ K+++ + + E+ + SK
Sbjct: 577 SAEARVKDIEKENKILHESIKETSSK 602
Score = 44.7 bits (104), Expect = 1e-04
Identities = 64/300 (21%), Positives = 138/300 (46%), Gaps = 36/300 (12%)
Query: 24 ESTSAHIIEETEYVKK----IRTTLQKIRT-QMFKDEIRHDSTNHKLDAKHCGNLQ---- 74
E+ H+ +E E ++K ++ T +KI + E+ ++ K NL
Sbjct: 631 ENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLE 690
Query: 75 --QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEM---NKENEVLKIKLQASREAGAAALRN 129
+ +S++D L ++ +K +++ ++ NKE E K +L+ E A+ +
Sbjct: 691 SLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKK 750
Query: 130 VAQRLFENYQ---TQSEEVRKKQEDSKQLLQ-----VNKLEKE-QKLKQHVENLNQVAEK 180
+RL +YQ +++ ++K E+S + +Q + LE E Q L++++E L +++
Sbjct: 751 T-ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKR 809
Query: 181 LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQ--DLQREISI 238
LE+ + LE ++EK+K+ L + L + ++K + + + +L++E
Sbjct: 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ-AEIKDTTLEENNVKIGNLEKENKT 868
Query: 239 LQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
L ++I + L+ + +E + L K + LRE + +++LKTQ
Sbjct: 869 LSKEIG----IYKESCVRLKELEKENKELVKRATIDIKTLVTLRE-----DLVSEKLKTQ 919
Score = 40.4 bits (93), Expect = 0.002
Identities = 60/320 (18%), Positives = 136/320 (42%), Gaps = 42/320 (13%)
Query: 24 ESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDP 83
E + + +ET ++K + L+K ++ + D+T + + K GNL++ + +
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVK-IGNLEKENKT---- 868
Query: 84 SCCSLDLLMKKI---KGKDLQLLEMNKENEVL------KIKLQASREAGAAALRNVAQRL 134
L K+I K ++L E+ KEN+ L IK + + + Q++
Sbjct: 869 -------LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 135 FENYQTQSEEVRK------------KQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLE 182
+ + + E+ K + D + L +KLE K ++ EK+
Sbjct: 922 NNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKE-----EKIA 976
Query: 183 EKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQ---LKSSATYGKSCQDLQREISIL 239
+++ E N Q++ +E +T+ + +L+ + + ++SS +RE
Sbjct: 977 ALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQET 1036
Query: 240 QEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ- 298
++ ++ + +N ++ E + LK LK+ + + NL+ ++ L+ Q L+ Q
Sbjct: 1037 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1096
Query: 299 VALSSETPRTKVSKAVSTSE 318
L ++ + +V + S+
Sbjct: 1097 TTLQTQNAKLQVENSTLNSQ 1116
Score = 40.0 bits (92), Expect = 0.003
Identities = 62/281 (22%), Positives = 120/281 (42%), Gaps = 41/281 (14%)
Query: 28 AHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCS 87
A + E T Y +++R L+ ++ + R D + G D++ + S
Sbjct: 980 ARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPIS----GEDNKWERE--S 1033
Query: 88 LDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRK 147
+ + +K KD +L+E+ + N L+ + QA L+ ++L ++
Sbjct: 1034 QETTRELLKVKD-RLIEVERNNATLQAEKQA--------LKTQLKQLETQNNNLQAQILA 1084
Query: 148 KQEDSKQLLQVNKLEKEQKLKQHVEN--LNQVAEKLEEKHSQI----TELENLVQRMEKE 201
Q + L + N + Q K VEN LN + L +++Q+ + LEN + + KE
Sbjct: 1085 LQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE 1144
Query: 202 KRTL--LERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRS 259
+ L L L +++ L+L +R+ S + IS + S H+NL
Sbjct: 1145 REDLKSLYDSLIKDHEKLELLH-----------ERQASEYESLISK-HGTLKSAHKNLEV 1192
Query: 260 VIQEMEGLKNNLKEQDKRIENLREKVNI------LEAQNKE 294
+++E N L +Q ++E+L + + + LE +N E
Sbjct: 1193 EHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHE 1233
Score = 39.3 bits (90), Expect = 0.005
Identities = 35/162 (21%), Positives = 80/162 (49%), Gaps = 21/162 (12%)
Query: 148 KQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLE 207
K+ +S+Q L V + + K+++ + ++LEEK Q+ + + +++ME E + L +
Sbjct: 241 KRTESRQHLSVELADAKAKIRR-------LRQELEEKTEQLLDCKQELEQMEIELKRLQQ 293
Query: 208 RKLSLENKLLQLKSSATY----------GKSCQDLQREISILQEQISHLQFVIHSQHQNL 257
++L L +S+ Y L+ E+S +E++ ++F ++ + L
Sbjct: 294 ENMNL---LSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEF-YKARVEEL 349
Query: 258 RSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
+ Q + K L++Q + +K++ LE +N +LK ++
Sbjct: 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL 391
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 64.7 bits (156), Expect = 1e-10
Identities = 79/345 (22%), Positives = 153/345 (44%), Gaps = 47/345 (13%)
Query: 21 ALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSE 80
AL +S S ++ E ++ L+++ Q K I +S N D + + E
Sbjct: 514 ALEKSQSEYLKISQEKEQQESLALEELELQ--KKAILTESENKLRDLQQEAETYRTRILE 571
Query: 81 MDPSCCSLDLLMKKIKGKDLQL---LEMNKENEVL-------KIKLQASREAGAAALRNV 130
++ S L K + KDL + E NK N+ + K +L++ + A
Sbjct: 572 LESSL-EKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK 630
Query: 131 AQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQ-VAEKLEEKHSQIT 189
Q L + YQT+ E++R+K E K+ L +KE + H+E +N+ EKL+ K +++
Sbjct: 631 LQVLKQQYQTEMEKLREKCEQEKETLLK---DKEIIFQAHIEEMNEKTLEKLDVKQTELE 687
Query: 190 ELENLVQRMEKEKRTLLER-----------KLSLENKLLQLKSSATYGKSCQDLQREISI 238
L + + + K + L E K LE K+ + K+ + E+SI
Sbjct: 688 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSI 747
Query: 239 ------LQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEA-- 290
L++QI+ L+ ++ + ++L+ +E L+ ++K + ++ K+++ ++
Sbjct: 748 QRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ 807
Query: 291 -----QNKELKTQVA------LSSETPRTKVSKAVSTSELKTEGV 324
Q K + Q+A L ET R ++K V+ E + + V
Sbjct: 808 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 852
Score = 55.1 bits (131), Expect = 9e-08
Identities = 82/380 (21%), Positives = 164/380 (43%), Gaps = 85/380 (22%)
Query: 20 SALYESTSAHIIEETEYVKK--------IRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCG 71
SA +E T A+ + + +K I T Q + K ++ + HK+ +
Sbjct: 808 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 867
Query: 72 NLQQGSDSEMDPSCCSLDLLMKK---------------IKGKDLQLLEMN----KENEVL 112
+ +SEM+ SL + + + K+ +L+M KE E+L
Sbjct: 868 QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEIL 927
Query: 113 KIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVE 172
KL A +E L + F+N + + E+V++K ++ ++ L+ L++E KLK+ +E
Sbjct: 928 TQKLSA-KEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELE 986
Query: 173 N----LNQV-----AEKLEEKHSQITELENLVQRMEKEKR------------------TL 205
N L+Q A+ LE + + + V R+E ++ ++
Sbjct: 987 NTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISI 1046
Query: 206 LERKLS----------------LENKLLQLKSS-ATYGKSCQDLQREISILQEQ------ 242
E+KL+ E ++ +LK +G +++ +EI+ L+E+
Sbjct: 1047 WEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDT 1106
Query: 243 -ISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVAL 301
++ LQ + + ++ S+ Q+ LK +L++ + + ++ L+ Q ELK +
Sbjct: 1107 TLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELK----M 1162
Query: 302 SSETPRTKVSKAVSTSELKT 321
+E + KVS+ TS+LKT
Sbjct: 1163 LAEEDKRKVSEL--TSKLKT 1180
Score = 53.9 bits (128), Expect = 2e-07
Identities = 78/374 (20%), Positives = 150/374 (40%), Gaps = 80/374 (21%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+++ +A HI ++T ++ + L+ Q +I H KL +H L
Sbjct: 1519 ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK---DIEHKELVQKL--QHFQELG 1573
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRL 134
+ D+ + + + L ++ +L KE E + + +++ E L+ + RL
Sbjct: 1574 EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEE----LKALEDRL 1629
Query: 135 FENYQTQSEEVRKKQEDS-----KQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQIT 189
+ E+++K E KQLL + ++EQ K +L+++ KL+E+ ++
Sbjct: 1630 ESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVH 1689
Query: 190 ELEN-----------------------------------LVQRMEKEKRTLLERKLSLEN 214
LE VQ+ +EK ++L+R L+ +
Sbjct: 1690 ILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKE 1749
Query: 215 KLLQLKS-------SATYGKSCQDLQREISIL---------QEQISHLQFVIHSQHQNLR 258
KLLQ S+ + CQ +R I + Q I HLQ + +++
Sbjct: 1750 KLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYS 1809
Query: 259 SVIQ---EMEGLKNNLKEQDKRIENLREKVN-----------ILEAQNKELKTQVALSSE 304
++ E EG KNN++ + + +EN+ + V ILE + KEL + + E
Sbjct: 1810 LIVAQHVEKEGGKNNIQAK-QNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKE 1868
Query: 305 TPRTKVSKAVSTSE 318
R ++ + S E
Sbjct: 1869 VHRVEMEELTSKYE 1882
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/289 (20%), Positives = 123/289 (42%), Gaps = 37/289 (12%)
Query: 30 IIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLD 89
++ +T V ++ L+++ + I H+L+ K N + ++++ +
Sbjct: 1264 LLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKE--NQIKSMKADIESLVTEKE 1321
Query: 90 LLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQ 149
L K+ G + Q KE+ + ++K + S A L EE+++K+
Sbjct: 1322 ALQKE--GGNQQQAASEKESCITQLKKELSENINAVTL-------------MKEELKEKK 1366
Query: 150 ED----SKQLLQVN-KLEKEQKLKQHVENLNQVAEKLEEKH----SQITELENLVQRMEK 200
+ SKQL +N +L+ L + ++ + ++ +E+ Q+ +L V + K
Sbjct: 1367 VEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSK 1426
Query: 201 EKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSV 260
EK + LE+ NK + K A Q + Q + LQ + + +
Sbjct: 1427 EKISALEQVDDWSNKFSEWKKKA---------QSRFTQHQNTVKELQIQLELKSKEAYEK 1477
Query: 261 IQEMEGLKNNLKEQDKRIENLREKV--NILEAQNKELKTQVALSSETPR 307
+++ LK L +Q+KR + L+ ++ + + + KE + L S+T R
Sbjct: 1478 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTAR 1526
Score = 47.0 bits (110), Expect = 2e-05
Identities = 62/310 (20%), Positives = 134/310 (43%), Gaps = 31/310 (10%)
Query: 24 ESTSAHIIEETEYVKKIRTTLQKIRTQM-FKDEIRHDSTNHKLDAKHCGNLQQGSDSEMD 82
ES ++E+ VK + T Q+++ Q + +HK + ++ ++D
Sbjct: 265 ESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLD 324
Query: 83 PSCCSLDLLMKKIKGKDLQLLEMNKENEVL---KIKLQASREAGAAALRNVAQRLFENYQ 139
L+ K KDL + E K L K ++ + + +++ E +
Sbjct: 325 ERLQELE------KIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 140 TQSEEVRKKQEDSKQLLQVNKLEKEQKLK------QHVENLNQVAEKLEEKHSQI-TELE 192
+ EE+ + + KQ+ + +EQK K + +E A+K EE ++ E++
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMD 438
Query: 193 NLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHS 252
++ +EK T E ++SL+ +L ++K D+ ++ S +EQI+ LQ +H
Sbjct: 439 EQIKTIEK---TSEEERISLQQELSRVKQEVV------DVMKKSS--EEQIAKLQ-KLHE 486
Query: 253 QH--QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKV 310
+ + + + ++++ + +EQ K + + +Q KE + +AL + K
Sbjct: 487 KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKA 546
Query: 311 SKAVSTSELK 320
S ++L+
Sbjct: 547 ILTESENKLR 556
Score = 45.8 bits (107), Expect = 5e-05
Identities = 78/337 (23%), Positives = 144/337 (42%), Gaps = 54/337 (16%)
Query: 24 ESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDP 83
+S H+ EE E K I Q + E ++ K + ++ + Q + E +
Sbjct: 1791 QSMIGHLQEELEEKNK---KYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKEL 1847
Query: 84 SCCSLDLLMKK-----IKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENY 138
+C L+ +K+ ++ K++ +EM + + KLQA ++ RN L E
Sbjct: 1848 TCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYE-KLQALQQMDG---RNKPTELLEE- 1902
Query: 139 QTQSEEVRKKQEDSKQLL-----QVNKLE--------KEQKLKQHVENLNQVAEKLEEKH 185
+EE K +LL Q N LE ++QKL + + L + L ++H
Sbjct: 1903 --NTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 1960
Query: 186 SQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREIS-------- 237
Q ELE L + ++E+ E K+ E + L+LK ++T + ++ +++
Sbjct: 1961 QQ--ELEILKKEYDQER----EEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2014
Query: 238 ILQEQISHLQFV------IHSQHQN--LRSVIQEMEGLKNNLKEQ----DKRIENLREKV 285
++E I+ Q V H + N L+ + ++ + LK K D R E + KV
Sbjct: 2015 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKV 2074
Query: 286 NILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
L+ Q +EL+ + E + V+ EL+T+
Sbjct: 2075 RDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQ 2111
Score = 43.1 bits (100), Expect = 3e-04
Identities = 59/297 (19%), Positives = 128/297 (43%), Gaps = 42/297 (14%)
Query: 27 SAHIIEETEYVKKIRTTLQKIRTQMFKD------------EIRHDSTNHKLDAKHCGNLQ 74
SAH+ + K++ L+K+ + K E++ + K +
Sbjct: 1119 SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKL 1178
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEV-LKI---KLQASREAGAAALRNV 130
+ +D E S + K ++ K L+ ++++E + L I K +A EA L N+
Sbjct: 1179 KTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINI 1238
Query: 131 AQRLFENYQTQSEEVRKKQEDSKQLLQVNKL---EKEQKLKQHVENLNQVAEKLEEKHSQ 187
+ ++ + + K+ L + E E +L+Q E N + ++ Q
Sbjct: 1239 SSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQ 1298
Query: 188 ITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQ 247
+ E EN ++ M+ + +L+ K +L+ + + +A+ +SC I+ L++++S
Sbjct: 1299 LEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC------ITQLKKELS--- 1349
Query: 248 FVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSE 304
+N+ +V +K LKE+ I +L +++ L N +L+ ++LS +
Sbjct: 1350 -------ENINAVTL----MKEELKEKKVEISSLSKQLTDL---NVQLQNSISLSEK 1392
Score = 40.0 bits (92), Expect = 0.003
Identities = 43/187 (22%), Positives = 91/187 (48%), Gaps = 10/187 (5%)
Query: 32 EETEYVKKI--RTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLD 89
+E E +KK + +KI+ + E++H+ST +L + L Q + E++ ++
Sbjct: 1962 QELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQ-KEQELE---MTIK 2017
Query: 90 LLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQ 149
+ K + + +LLE ++E +K A ++ L+ A+R E + EE+ K
Sbjct: 2018 ETINKAQEVEAELLESHQEETNQLLKKIAEKDDD---LKRTAKRYEEILDAREEEMTAKV 2074
Query: 150 EDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERK 209
D + L+ + + +QKL+Q EN + E +Q+ + L+ + +++ E+
Sbjct: 2075 RDLQTQLEELQKKYQQKLEQE-ENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQI 2133
Query: 210 LSLENKL 216
+LE++L
Sbjct: 2134 HNLEDRL 2140
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 63.9 bits (154), Expect = 2e-10
Identities = 84/332 (25%), Positives = 144/332 (43%), Gaps = 34/332 (10%)
Query: 17 EDNSALYESTSAHIIEETEYVKKIRTTLQK--IRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+ N + E I E+ E +K + L+ I+ ++E+ T + K +L+
Sbjct: 724 QPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLK 783
Query: 75 QGSDSEMDPSCCSLDLLMKKI---KGKDLQLLEMNKENEVLKIK-----LQASREAGAAA 126
+ ++ S SL +KK+ K ++ +E E E+LK+ +Q S +
Sbjct: 784 AKQNDQV--SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQE 841
Query: 127 LRNVAQRLFENYQTQSEEVRKKQED----SKQLLQVNKLEKEQKLKQHVENLNQVAEKLE 182
L+N+ + E T + +K++D K L + E+ + LK HV+ + Q K
Sbjct: 842 LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ--EENESLKAHVQEVAQHNLKEA 899
Query: 183 EKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQ 242
SQ ELE +++ E E + L E+ L SS T + QD+Q E + + Q
Sbjct: 900 SSASQFEELEIVLKEKENELKRLEAMLKERESDL----SSKT--QLLQDVQDENKLFKSQ 953
Query: 243 ISHLQFVIHSQ------HQNLRSVIQEME----GLKNNLKEQDKRIENLREKVNILEAQN 292
I L+ + Q H+ L VI E E GL N L +E+ R+K N L +N
Sbjct: 954 IEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKN 1013
Query: 293 KELKTQVALSSETPRTKVSKAVSTSELKTEGV 324
E +A + + + KV+K + + E V
Sbjct: 1014 WEAMEALASTEKMLQDKVNKTSKERQQQVEAV 1045
Score = 46.6 bits (109), Expect = 3e-05
Identities = 65/314 (20%), Positives = 140/314 (44%), Gaps = 42/314 (13%)
Query: 45 QKIRTQMFKDEIRHDSTNHKLDAKHCG--NLQQGSDSEMDPSCCSLDLLMKKIKGKDLQL 102
+++++ + K H++ L +K N Q S++ + S L +++ +QL
Sbjct: 498 EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRL----MQL 553
Query: 103 LE-----MNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
+E +NKE E L++++Q E A L+ Q+ Q+ +E K +
Sbjct: 554 MESEQKRVNKE-ESLQMQVQDILEQNEA-LKAQIQQFHSQIAAQTSASVLAEELHKVIA- 610
Query: 158 VNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENL--VQRMEKEKRTLLERKLSLENK 215
EK++++KQ ++L ++L K ++ +++N+ + + E +K L + +
Sbjct: 611 ----EKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAH 666
Query: 216 LLQLKSSATYGKSC------QDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGL-- 267
L+ + Y K + LQ EIS E+ +++ Q++ L+S +Q+++ L
Sbjct: 667 ELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK----ILNDQNKALKSEVQKLQTLVS 722
Query: 268 ----KNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSE------TPRTKVSKAVSTS 317
K+ +++ +K I+ EK+ +E + QVA E T + ++K V
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 318 ELKTEGVSPYLMLI 331
+ K + L+
Sbjct: 783 KAKQNDQVSFASLV 796
Score = 37.0 bits (84), Expect = 0.025
Identities = 59/275 (21%), Positives = 114/275 (41%), Gaps = 54/275 (19%)
Query: 38 KKIRTTLQKIRTQMFKDEIRH------------DSTNHKLDAKHCGNLQQGSDSEMDPSC 85
++++ Q++R QM + EI H +T ++L++K L + D +
Sbjct: 402 QQMQMKFQQVREQM-EAEIAHLKQENGILRDAVSNTTNQLESKQSAELNK---LRQDYAR 457
Query: 86 CSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV 145
+L K K + ++ + N E ++K+Q A+R +E Q+ +
Sbjct: 458 LVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQE----------AERRWEEVQSYIRKR 507
Query: 146 RKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTL 205
+ E ++Q LQ + KE ++ + HS++T+ Q++E+ L
Sbjct: 508 TAEHEAAQQDLQSKFVAKENEV--------------QSLHSKLTDTLVSKQQLEQRLMQL 553
Query: 206 LERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEME 265
+E + NK L+ QD+ + L+ QI HSQ S E
Sbjct: 554 MESEQKRVNKEESLQMQV------QDILEQNEALKAQIQQ----FHSQIAAQTSASVLAE 603
Query: 266 GLKNNLKEQDKRI----ENLREKVNILEAQNKELK 296
L + E+DK+I ++L + + L ++ +ELK
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
Score = 30.8 bits (68), Expect = 1.8
Identities = 44/227 (19%), Positives = 102/227 (44%), Gaps = 26/227 (11%)
Query: 106 NKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQ 165
++E +VL+ KL+ + E + + Q E Y++ V + E Q LQ + ++E
Sbjct: 1089 SEEVKVLEHKLKEADE-----MHTLLQLECEKYKS----VLAETEGILQKLQRSVEQEEN 1139
Query: 166 KLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATY 225
K K V+ ++ ++++ S T E ++R+ E + + + E+ ++L+ +
Sbjct: 1140 KWKVKVDESHKTIKQMQ---SSFTSSEQELERLRSENKDIENLRREREHLEMELEKA--- 1193
Query: 226 GKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKV 285
+ E S ++ L+ ++ LR+ E + + +L + + +E ++ K
Sbjct: 1194 -------EMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSK- 1245
Query: 286 NILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTEGVSPYLMLIR 332
I++A T + S +P T+ S+ + S + V+ L++
Sbjct: 1246 -IVKAAGD--TTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQ 1289
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 62.4 bits (150), Expect = 6e-10
Identities = 70/309 (22%), Positives = 143/309 (46%), Gaps = 39/309 (12%)
Query: 29 HIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAK--------HCGNLQQGSDSE 80
H+ E+ E + K+R + + ++ + +++N KL K H + +E
Sbjct: 1782 HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNE 1841
Query: 81 MDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQT 140
++ L K+IK + L L ++ EN L KL + E + ++ +N +
Sbjct: 1842 TQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKER-----DNLRR 1896
Query: 141 QSEEVRKKQEDSKQLLQVNK---LEKEQKLK-------QHVENLNQVAEKLEEKHSQITE 190
E ++ +++ K+ LQ K LE +Q+LK +H E ++++ EK+ EK QI++
Sbjct: 1897 VEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISD 1956
Query: 191 LENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYG-KSCQDLQREISILQEQISHLQFV 249
++ + + + E + ++ E +LL++K K ++++ + Q +Q V
Sbjct: 1957 IQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSV 2016
Query: 250 ----------IHSQHQNLRSVIQEMEGL---KNNLK-EQDKRIENLREKVNILEAQNKEL 295
+H + +R V +E + L K +LK E+D+ I LRE + + QN ++
Sbjct: 2017 RMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMI-ARDRQNHQV 2075
Query: 296 KTQVALSSE 304
K + L S+
Sbjct: 2076 KPEKRLLSD 2084
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/269 (25%), Positives = 115/269 (42%), Gaps = 43/269 (15%)
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRL 134
Q DS + L ++++ K ++ E E E LK +L+ +R++ + +
Sbjct: 855 QKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLE-NRDSTLQTVEREKTLI 913
Query: 135 FENYQTQSEEVR---KKQEDSKQLLQVNKLEKEQ------------------------KL 167
E Q EEV+ ++++D KQL + ++E++Q L
Sbjct: 914 TEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESL 973
Query: 168 KQHVENLNQVAEKLEEKHSQITELENLVQRMEKE---KRTLLERKLSLENKLLQLKSSAT 224
KQH E +N + K+ E+ S+ +E + E K +++K LE K Q ++
Sbjct: 974 KQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADV 1033
Query: 225 YGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQ-DKRIENLRE 283
+ QR+I L ++ + LQ Q L SVI E E LK +LKE + IEN E
Sbjct: 1034 KDNEIIEQQRKIFSLIQEKNELQ-------QMLESVIAEKEQLKTDLKENIEMTIENQEE 1086
Query: 284 KVNILEAQNKELKTQVALSSETPRTKVSK 312
L ELK Q + ++ + K
Sbjct: 1087 ----LRLLGDELKKQQEIVAQEKNHAIKK 1111
Score = 57.0 bits (136), Expect = 2e-08
Identities = 56/280 (20%), Positives = 134/280 (47%), Gaps = 19/280 (6%)
Query: 30 IIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLD 89
+I+E E +K+++ LQ R Q+ ++ + + K L+ + +E C ++
Sbjct: 1588 MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIE 1647
Query: 90 LLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQ 149
L ++ + + L L + EN I+L +R+V + ++ ++ E ++ ++
Sbjct: 1648 HLKEQFETQKLNLENIETEN----IRLTQILHENLEEMRSVTKER-DDLRSVEETLKVER 1702
Query: 150 EDSKQLLQ---VNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKE----K 202
+ K+ L+ LEK+++LK +L + E +++ ++E N + M+K+
Sbjct: 1703 DQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN 1762
Query: 203 RTLLERKLSLENKL----LQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLR 258
L + L ++ +L + LK ++ L+ +S +++S++Q + + + L+
Sbjct: 1763 DALKAQDLKIQEELRIAHMHLKEQQ---ETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQ 1819
Query: 259 SVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
IQE++ ++ L K + ++KV+ +E K++K Q
Sbjct: 1820 EKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQ 1859
Score = 55.5 bits (132), Expect = 7e-08
Identities = 75/324 (23%), Positives = 138/324 (42%), Gaps = 66/324 (20%)
Query: 32 EETEYVKKIRTTLQKIRTQMFKDEIRHDS-------TNHKLDAKHCGNLQQGSDSEMDPS 84
EE + + K R L+ I+ + E++HD T K+ Q + E D
Sbjct: 1342 EEIKSLTKERDNLKTIKEAL---EVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNE 1398
Query: 85 CCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREA--GAAALRNVAQRLFENYQTQS 142
+ M++ K KD LL + E L +LQ S + A ++ QRL E Q++S
Sbjct: 1399 TTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSES 1458
Query: 143 EEVR------------------------KKQEDSKQLLQVNKLEKEQKLKQHVENLNQVA 178
++++ K+QE++ L+VN EKE ++ + L +
Sbjct: 1459 DQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAIN 1518
Query: 179 EKLEEKHSQITELE---NLVQRME-----------KEKRTLLERKL-SLENKLLQLKSSA 223
+KL+ K +I E E N+ Q E KE R + L S+E+K+L+L +
Sbjct: 1519 DKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTN-- 1576
Query: 224 TYGKSCQDLQREISIL---QEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKR--- 277
Q+ Q EI I+ +E++ +Q + + L+ +E+ +E++ +
Sbjct: 1577 ----RLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLK 1632
Query: 278 ---IENLREKVNILEAQNKELKTQ 298
+ +EK+ +E ++ +TQ
Sbjct: 1633 MTAVNETQEKMCEIEHLKEQFETQ 1656
Score = 53.1 bits (126), Expect = 3e-07
Identities = 78/317 (24%), Positives = 139/317 (43%), Gaps = 53/317 (16%)
Query: 35 EYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQ---GSDSEMDPSCCSLDLL 91
++ + I T KI ++ ++ ++T D QQ G D + D + L
Sbjct: 975 QHQETINTLKSKISEEVSRNLHMEENTGETKD-----EFQQKMVGIDKKQDLEAKNTQTL 1029
Query: 92 MKKIKGKDLQLLEMNKENEVL---KIKLQASREAGAAALRNVAQRLFENYQT---QSEEV 145
+K D +++E ++ L K +LQ E+ A + L EN + EE+
Sbjct: 1030 TADVK--DNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEEL 1087
Query: 146 R------KKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITE-------LE 192
R KKQ++ + + ++KE +L + + L +V EKL+EK Q+ E ++
Sbjct: 1088 RLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQ 1147
Query: 193 NLVQRMEKEKRTLLERKLSLENKLLQLKSSAT-----YGKSCQDLQREISILQEQ--ISH 245
+ M+K+ + K L+NK L L+ T K ++ + SI +E+ +
Sbjct: 1148 EEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKE 1207
Query: 246 LQFVIHSQHQNLRSVIQEME--GLKN---------NLKEQDKRIENLREKVN-----ILE 289
LQ ++ +LR I+E+E GL+ +LKE + I+ LR V+ I+
Sbjct: 1208 LQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIIN 1267
Query: 290 AQNKELKTQVALSSETP 306
Q+ E K+ L E P
Sbjct: 1268 TQDLE-KSHTKLQEEIP 1283
Score = 48.5 bits (114), Expect = 8e-06
Identities = 67/319 (21%), Positives = 137/319 (42%), Gaps = 43/319 (13%)
Query: 31 IEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDL 90
+E E +K++ TT + QM D + S +L+AK +Q + E+ + +
Sbjct: 649 LELKEKMKELATTYK----QMENDIQLYQS---QLEAKK--KMQVDLEKELQSAFNEITK 699
Query: 91 LMKKIKGK---DLQLLEMNKENEVLKIKLQASREAGA-AALRNVAQRLFE--NYQTQSEE 144
L I GK DL L + E ++ ++ + ++E ALR L E + ++ E
Sbjct: 700 LTSLIDGKVPKDL-LCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVER 758
Query: 145 VRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEE-----------------KHSQ 187
+RK+ +D + L + EK++ + V ++V LEE +
Sbjct: 759 LRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQE 818
Query: 188 ITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQ 247
+ L E++ + +LE + +++ L K Q + L+ ++S+
Sbjct: 819 FQNFKTLHMDFEQKYKMVLEENERMNQEIVNL------SKEAQKFDSSLGALKTELSYKT 872
Query: 248 FVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENL-REKVNI---LEAQNKELKTQVALSS 303
+ + + ++ + EME LK L+ +D ++ + REK I L+ +E+KT
Sbjct: 873 QELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKD 932
Query: 304 ETPRTKVSKAVSTSELKTE 322
+ + + S + +LK++
Sbjct: 933 DLKQLQESLQIERDQLKSD 951
Score = 46.6 bits (109), Expect = 3e-05
Identities = 66/312 (21%), Positives = 140/312 (44%), Gaps = 51/312 (16%)
Query: 13 RDKMEDNSALYESTSAHIIEETE------YVKKIRTTLQKIRTQMFKDEIRHDSTNHKLD 66
RD++++N L E+ + + ++ E ++K+ + T+ K+R + E ++ +N + D
Sbjct: 1702 RDQLKEN--LRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIV--SEKTNEISNMQKD 1757
Query: 67 AKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAA 126
+H + + D ++ + +K+ + +L + E +Q E A
Sbjct: 1758 LEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAK 1817
Query: 127 LRNVAQRLFENYQ---TQSEEVRKKQEDSKQLLQVNKLEKEQKL---KQHVENLNQVAEK 180
L+ Q L N T ++V + Q+ ++ Q+ K K+Q L K +ENLN +A+K
Sbjct: 1818 LQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLN-LAQK 1876
Query: 181 LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ 240
L H + E++++++ + +R +E L LE QLK S K+ +DL+
Sbjct: 1877 L---HENLEEMKSVMKERDNLRR--VEETLKLERD--QLKESLQETKA-RDLE------- 1921
Query: 241 EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA 300
+ QE++ + KE + ++ LREK++ Q +++ +
Sbjct: 1922 -------------------IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLD 1962
Query: 301 LSSETPRTKVSK 312
S + + K+ +
Sbjct: 1963 KSKDELQKKIQE 1974
Score = 44.3 bits (103), Expect = 2e-04
Identities = 46/250 (18%), Positives = 113/250 (45%), Gaps = 22/250 (8%)
Query: 91 LMKKIKGKDLQLLEMNKENEVLKI---KLQASREAGAAALRNVAQRLFENYQTQSEEVRK 147
L +K + ++ + KE + LK L+ + +R ++ E+ Q + +
Sbjct: 1333 LNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNM 1392
Query: 148 KQEDSKQLLQVNKLE----KEQKLKQHVENLNQVAEKLEEKHSQI-------TELENLVQ 196
K++D++ V+++E K+ L + + ++++L+E H ++ +L+ L +
Sbjct: 1393 KEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQE 1452
Query: 197 RMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQRE-ISILQEQISHLQFVIHSQHQ 255
++ E L E + K L+ + C Q E I+ L+ +S + I + +
Sbjct: 1453 VLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQK 1512
Query: 256 NLRSVIQEMEGLKNNLKEQD-----KRIENLREKVNILE--AQNKELKTQVALSSETPRT 308
L ++ +++ + E++ K+I ++EKVN L+ ++++ K S E+
Sbjct: 1513 QLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKML 1572
Query: 309 KVSKAVSTSE 318
+++ + S+
Sbjct: 1573 ELTNRLQESQ 1582
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/261 (21%), Positives = 116/261 (44%), Gaps = 29/261 (11%)
Query: 87 SLDLLMKKIKGKDLQLL---EMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSE 143
++D L + + K Q++ ++ K + L+ ++ E L NV + + E +T +E
Sbjct: 1250 TIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE-QELLPNVKE-VSETQETMNE 1307
Query: 144 -EVRKKQEDSKQLLQVNKLEKEQ---------------KLKQHVENLNQVAEKLEEKHSQ 187
E+ +Q +K + ++E E+ L + +NL + E LE KH Q
Sbjct: 1308 LELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQ 1367
Query: 188 ITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQ 247
+ E ++ + + K + + +++ SL K +++ + Q ++ ++L+ +I L
Sbjct: 1368 LKE--HIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLG 1425
Query: 248 FV--IHSQHQNLRSVIQEMEGLKNNLK----EQDKRIENLREKVNILEAQNKELKTQVAL 301
+ H ++SV +E + L+ + E D+ EN++E V +ELK
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCC 1485
Query: 302 SSETPRTKVSKAVSTSELKTE 322
E T V+ SE +TE
Sbjct: 1486 LKEQEETINELRVNLSEKETE 1506
Score = 43.5 bits (101), Expect = 3e-04
Identities = 63/282 (22%), Positives = 132/282 (46%), Gaps = 33/282 (11%)
Query: 55 EIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKG-KDLQLLEMNKENEVLK 113
++ H+ +N K KH Q ++E+ ++LL +K K LQ +++ E +K
Sbjct: 551 QLIHEISNLKNLVKHAEVYNQDLENELSSK---VELLREKEDQIKKLQEYIDSQKLENIK 607
Query: 114 IKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVEN 173
+ L S E+ + + Q LF+ +E V + L+ LE ++K+K+
Sbjct: 608 MDLSYSLES-IEDPKQMKQTLFD-----AETVALDAKRESAFLRSENLELKEKMKELATT 661
Query: 174 LNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQ 233
Q+ ++ SQ+ + + +EKE + S N++ +L +S GK +DL
Sbjct: 662 YKQMENDIQLYQSQLEAKKKMQVDLEKELQ-------SAFNEITKL-TSLIDGKVPKDLL 713
Query: 234 REISILQEQISHLQFVIH---SQHQNLRS---VIQEMEGLKNNLKEQDKRIENLREKVNI 287
+ L+ +I+ LQ ++ +++ LR ++ E++ L + ++ K I++ E+++I
Sbjct: 714 CNLE-LEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHI 772
Query: 288 LEAQNKELKTQV--------ALSSETPRTKVSKAVSTSELKT 321
+ ++ +L ++V L E +TK A + S K+
Sbjct: 773 ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Score = 43.5 bits (101), Expect = 3e-04
Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 23/184 (12%)
Query: 134 LFENYQTQSEEVRKKQEDSK--QLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITEL 191
L EN + E V +E K L K E K ++ E +V E+L E +L
Sbjct: 837 LEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQL 896
Query: 192 EN---LVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQF 248
EN +Q +E+EK + E+ L+ L ++K+ + LQ + I ++Q+
Sbjct: 897 ENRDSTLQTVEREKTLITEK---LQQTLEEVKTLTQEKDDLKQLQESLQIERDQLK---- 949
Query: 249 VIHSQHQNLRSVIQEMEGLKN---NLKEQDKRIENLREKVNILEAQNKELKTQVALSSET 305
H + I E L+N +LK+ + I L+ K+ ++E+ + + T
Sbjct: 950 --SDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKI------SEEVSRNLHMEENT 1001
Query: 306 PRTK 309
TK
Sbjct: 1002 GETK 1005
Score = 41.6 bits (96), Expect = 0.001
Identities = 65/298 (21%), Positives = 126/298 (42%), Gaps = 63/298 (21%)
Query: 22 LYESTSAHIIEETEYVKKIRTT-----LQKIRTQMFKDEIRHDST----NHKLDAKHCGN 72
L S+S + +E + +K R T + K++ + D+ + HKL
Sbjct: 401 LVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLRE 460
Query: 73 LQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQ 132
+ + SE D +LD L + +E N ++L Q + E+ +LR
Sbjct: 461 IDESVCSESDVFSNTLDTLSE---------IEWNPATKLLN---QENIESELNSLRADYD 508
Query: 133 RL---FENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQIT 189
L +E +T+ EE+ K ++ L + LE++ K Q ++ ++ +I+
Sbjct: 509 NLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIH-----------EIS 557
Query: 190 ELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFV 249
L+NLV+ E + LE +LS + +LL+ K ++QI LQ
Sbjct: 558 NLKNLVKHAEVYNQD-LENELSSKVELLREK-------------------EDQIKKLQEY 597
Query: 250 IHSQH-QNLR-------SVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
I SQ +N++ I++ + +K L + + + + + L ++N ELK ++
Sbjct: 598 IDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKM 655
Score = 40.4 bits (93), Expect = 0.002
Identities = 63/313 (20%), Positives = 126/313 (40%), Gaps = 54/313 (17%)
Query: 9 EIPPRD----KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFK-DEIRHDSTNH 63
++P R+ K+ N L+ E+E+ I+T Q++ + + + + N
Sbjct: 2220 DVPSRELRDLKLNQNMDLHIEEILKDFSESEF-PSIKTEFQQVLSNRKEMTQFLEEWLNT 2278
Query: 64 KLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAG 123
+ D + L+ G E D C + +I + ++ + E E + E
Sbjct: 2279 RFDIE---KLKNGIQKENDRICQVNNFFNNRI----IAIMNESTEFEERSATISKEWEQD 2331
Query: 124 AAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEE 183
+L+ ++LF+NYQT + QVN ++ K HV
Sbjct: 2332 LKSLKEKNEKLFKNYQTLKTSLASGA-------QVNPTTQDNK-NPHVT----------- 2372
Query: 184 KHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQ 242
S+ T+L E+ LEN L + K SA + +S +Q+E+ + +
Sbjct: 2373 --SRATQLTT-------------EKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDI 2417
Query: 243 ISHLQFVIHSQHQNLRSVIQEMEGLKNNL----KEQDKRIENLREKVNILEAQNKELKTQ 298
I+ LQ +H ++ L + ++ L++ + K + IE+L K+ +++ +++K
Sbjct: 2418 IAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDL--KMKLVKIDLEKMKNA 2475
Query: 299 VALSSETPRTKVS 311
E TK +
Sbjct: 2476 KEFEKEISATKAT 2488
Score = 35.0 bits (79), Expect = 0.094
Identities = 50/247 (20%), Positives = 102/247 (41%), Gaps = 31/247 (12%)
Query: 103 LEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQS---------EEVRKKQEDSK 153
L+ +E ++ I L+ +E R+V+++ + TQ EE+ E+ +
Sbjct: 1231 LQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQE 1290
Query: 154 QLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENL------------VQRMEKE 201
L V ++ + Q+ +E L + + + E+E L ++ + KE
Sbjct: 1291 LLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKE 1350
Query: 202 KRTLLERKLSLENKLLQLKS--SATYGK--SCQDLQREISILQEQISHLQFVIHSQHQ-- 255
+ L K +LE K QLK T K Q Q + ++E+ + ++ Q
Sbjct: 1351 RDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFK 1410
Query: 256 ----NLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVS 311
L + EM GL L+E ++++ ++ + L+ + L+++ E + V+
Sbjct: 1411 PKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVA 1470
Query: 312 KAVSTSE 318
K + T E
Sbjct: 1471 KHLETEE 1477
Score = 32.0 bits (71), Expect = 0.80
Identities = 44/215 (20%), Positives = 97/215 (45%), Gaps = 14/215 (6%)
Query: 104 EMNKENEVL-KIK-LQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKL 161
E+ K+ E+L KI+ LQ + + LR++ +L +N EE+ K +S+ K
Sbjct: 2201 EVEKQKELLIKIQHLQQDCDVPSRELRDL--KLNQNMDLHIEEILKDFSESE--FPSIKT 2256
Query: 162 EKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKS 221
E +Q L N ++ + LEE + ++E L ++KE + + N+++ + +
Sbjct: 2257 EFQQVLS----NRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMN 2312
Query: 222 SAT-YGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN 280
+T + + + +E + + + +Q L++ + G + N QD + +
Sbjct: 2313 ESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSL--ASGAQVNPTTQDNKNPH 2370
Query: 281 LREKVNILEAQN-KELKTQVALSSETPRTKVSKAV 314
+ + L + +EL+ + + E+ K SK +
Sbjct: 2371 VTSRATQLTTEKIRELENSLHEAKESAMHKESKII 2405
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 62.0 bits (149), Expect = 7e-10
Identities = 60/272 (22%), Positives = 120/272 (44%), Gaps = 27/272 (9%)
Query: 54 DEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLK 113
+E+R T K + + + + E + C L KK++ +L E +E E +
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 114 IKLQASREAGAAALRNVAQR--LFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHV 171
KLQ + A L+ + + + E+ + + +K ED N E+E+K K
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS-- 1017
Query: 172 ENLNQVAEKLEEKH-SQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQ 230
KL+ KH + IT+LE ++R EK+++ L + + LE
Sbjct: 1018 ------LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEG-------------DST 1058
Query: 231 DLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEA 290
DL +I+ LQ QI+ L+ + + + L++ + +E +++ ++ +RE + +
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVE---EEAAQKNMALKKIRELESQISE 1115
Query: 291 QNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
++L+++ A ++ + K LKTE
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
Score = 58.2 bits (139), Expect = 1e-08
Identities = 53/293 (18%), Positives = 131/293 (44%), Gaps = 18/293 (6%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
++E+ +A I E + +++ L+ R K E + +L+A L+
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA-----LK 1145
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRL 134
+ +D + +L K+ + ++ + +E + + ++Q R+ + A+ +A++L
Sbjct: 1146 TELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL 1205
Query: 135 FENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENL 194
Q++ V+ E +KQ L+ + E ++K ++ K ++ +Q+ EL+
Sbjct: 1206 -----EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 195 VQRMEKEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQISHLQFVIHSQ 253
E+ + L ++ L+ +L + + S L ++ S L+ Q+ Q ++ +
Sbjct: 1261 FNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEE 1320
Query: 254 HQ-------NLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
++ L+ V E + L+E+++ NL +++ L AQ ++K ++
Sbjct: 1321 NRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
Score = 53.5 bits (127), Expect = 3e-07
Identities = 70/343 (20%), Positives = 151/343 (44%), Gaps = 33/343 (9%)
Query: 3 TVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKD-------- 54
T +T E + +E+ + E +K R L+K R ++ D
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 55 -EIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLK 113
E++ K+ Q + + ++ ++ +KKI+ + Q+ E+ ++ E
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE--- 1121
Query: 114 IKLQASREAGAAALRNVAQRLFENYQTQSEEV-----RKKQEDSKQLLQVNKLEK--EQK 166
+ASR R++ + L E +T+ E+ +++ SK+ +VN L+K E++
Sbjct: 1122 -SERASRNKAEKQKRDLGEEL-EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Query: 167 LKQHVENLNQVAEK----LEEKHSQITELENLVQRMEKEKRTLLERKLSLENK---LLQL 219
K H + ++ +K +EE Q+ + + + +EK K+TL + L N+ LLQ
Sbjct: 1180 AKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQG 1239
Query: 220 KSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIE 279
K + + + + ++ ++ LQ + + + V + + E++ + L + D +
Sbjct: 1240 KGDSEHKR--KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSS 1297
Query: 280 NLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
L + + LE+Q ++ TQ L E R K+S + +++ E
Sbjct: 1298 KLTKDFSALESQLQD--TQELLQEEN-RQKLSLSTKLKQVEDE 1337
Score = 47.0 bits (110), Expect = 2e-05
Identities = 63/298 (21%), Positives = 119/298 (39%), Gaps = 28/298 (9%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+++D L + + + + +K++ R Q+ ++E + ++ H
Sbjct: 1309 QLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVAD 1368
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKI-KLQASREAGAAALRNVAQR 133
E C +K+ KDL+ L E +V KL+ ++ L ++
Sbjct: 1369 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD 1428
Query: 134 LFENYQTQSE-EVRKKQEDSKQLLQVNKL----------EKEQKLKQHVENLNQVAEKLE 182
L ++Q QS + KKQ+ QLL K E + ++ +A LE
Sbjct: 1429 L--DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALE 1486
Query: 183 EKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQ 242
E Q ELE R+ K+ RT +E +S S GKS +L++ L++Q
Sbjct: 1487 EAMEQKAELE----RLNKQFRTEMEDLMS---------SKDDVGKSVHELEKSKRALEQQ 1533
Query: 243 ISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIE-NLREKVNILEAQNKELKTQV 299
+ ++ + L++ L+ NL+ + E +L+ + E + K+L QV
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQV 1591
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/269 (17%), Positives = 118/269 (43%), Gaps = 31/269 (11%)
Query: 93 KKIKGKDLQLLEMNKENEVL-KIKLQASRE-----------AGAAALRNVAQRLFENYQT 140
KK+K + +++++ +E + K QA +E +G AL +R E
Sbjct: 1673 KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIA 1732
Query: 141 QSEEVRKKQEDSKQL---------LQVNKLEKEQKLKQ-HVENLNQVAEKLEEKHSQIT- 189
Q EE ++++ + +L LQ++++ + L++ H + ++LE ++ ++
Sbjct: 1733 QLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV 1792
Query: 190 ---ELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHL 246
E+E V+ K T LE K++ + L ++ +C+ ++R ++++ +
Sbjct: 1793 KLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQA-ACKQVRRT----EKKLKDV 1847
Query: 247 QFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETP 306
+ + +N + + LK+ +++E E+ A ++L+ ++ ++ET
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907
Query: 307 RTKVSKAVSTSELKTEGVSPYLMLIRLRK 335
+ S G P+++ R+ +
Sbjct: 1908 DAMNREVSSLKNKLRRGDLPFVVPRRMAR 1936
Score = 45.8 bits (107), Expect = 5e-05
Identities = 62/325 (19%), Positives = 145/325 (44%), Gaps = 29/325 (8%)
Query: 13 RDKMEDNSALYEST--SAHIIEET-----EYVKKIRTTLQKIRTQMFKDE---IRHDSTN 62
R +MED + + S H +E++ + V++++T L+++ ++ E +R +
Sbjct: 1503 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL 1562
Query: 63 HKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREA 122
+ A+ +LQ G D + + L +++++ + LE ++ + + + E
Sbjct: 1563 QAMKAQFERDLQ-GRDEQSEEKKKQLVRQVREMEAE----LEDERKQRSMAVAARKKLEM 1617
Query: 123 GAAALRNVAQRLFENYQTQSEEVRKKQ---EDSKQLLQVNKLEKEQKLKQHVENLNQVAE 179
L +N +++RK Q +D + L + +E+ L Q EN +
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKEN----EK 1673
Query: 180 KLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYG-KSCQDLQREISI 238
KL+ +++ +L+ + E+ KR + + L +++ + + L+ I+
Sbjct: 1674 KLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQ 1733
Query: 239 LQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNL---KEQDKRIENLREKVNILEAQNKEL 295
L+E++ Q + L+ +++ + +L + ++ EN R++ LE QNKEL
Sbjct: 1734 LEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQ---LERQNKEL 1790
Query: 296 KTQVALSSETPRTKVSKAVSTSELK 320
K ++ T ++K +++ E K
Sbjct: 1791 KVKLQEMEGTVKSKYKASITALEAK 1815
Score = 35.8 bits (81), Expect = 0.055
Identities = 32/139 (23%), Positives = 69/139 (49%), Gaps = 10/139 (7%)
Query: 187 QITELENLVQRMEKEKRTLLERKLSLENKL-----LQLKSSATYGKSCQDLQREISILQE 241
Q++ E + E+E + E++L+ EN+L LQ + A + + LQ E + E
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 242 QISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVAL 301
L+ + ++ Q L + ++E ++E+++R ++L+ + ++ +EL+ Q+
Sbjct: 899 -AEELRARLTAKKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLE- 953
Query: 302 SSETPRTKVSKAVSTSELK 320
E+ R K+ T+E K
Sbjct: 954 EEESARQKLQLEKVTTEAK 972
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 60.8 bits (146), Expect = 2e-09
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 27/258 (10%)
Query: 88 LDLLMKKIKGKDLQLLEMNKENEVLK-----IKLQASREAGAAALRNVAQRLFENYQTQS 142
L+ + K+ K+ + ++ +E + LK ++L+ +++ + Q L + + Q
Sbjct: 817 LEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQM 876
Query: 143 EEVRKK-QEDSKQLLQVNKL-----EKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQ 196
++ +E K L K E+ + LK HV+ + Q K SQ ELE +++
Sbjct: 877 NTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLK 936
Query: 197 RMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQ--- 253
E E + L E+ L SS T + QD+Q E + + QI L+ + Q
Sbjct: 937 EKENELKRLEAMLKERESDL----SSKT--QLLQDVQDENKLFKSQIEQLKQQNYQQASS 990
Query: 254 ---HQNLRSVIQEME----GLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETP 306
H+ L VI E E GL N L +E+ R+K N L +N E +A + +
Sbjct: 991 FPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKML 1050
Query: 307 RTKVSKAVSTSELKTEGV 324
+ KV+K + + E V
Sbjct: 1051 QDKVNKTSKERQQQVEAV 1068
Score = 49.7 bits (117), Expect = 4e-06
Identities = 83/368 (22%), Positives = 161/368 (43%), Gaps = 84/368 (22%)
Query: 24 ESTSAHIIEETE---YVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSE 80
++ +AH +E+ + YVK KIR + +++++H+ +N + K + + SE
Sbjct: 661 QAAAAHELEKMQQSVYVKD-----DKIR--LLEEQLQHEISNKMEEFKILNDQNKALKSE 713
Query: 81 MD---------PSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVA 131
+ P+ ++ + K I+ KD +L + + E I++ A++E A+R
Sbjct: 714 VQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQV-ATKEEELNAIRTEN 772
Query: 132 QRLFENYQTQSEEVRKKQEDSKQLLQVNKL--EKEQKLK-----------------QHVE 172
L + Q + + + + ++ K+ EK+ K+K + V+
Sbjct: 773 SSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Query: 173 NLNQVAEKLEEK--------------HSQITELENLVQRMEKEKRTLLERKLSLENKLLQ 218
+L Q + L+E+ S++ EL+NL++ E++ T+ K LE K
Sbjct: 833 DLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM---KAVLEEK--- 886
Query: 219 LKSSATYGKSCQDLQREISILQEQISHLQFVIH---------SQHQNLRSVIQEMEG--- 266
K A GK QDLQ E L+ +H+Q V SQ + L V++E E
Sbjct: 887 EKDLANTGKWLQDLQEENESLK---AHVQEVAQHNLKEASSASQFEELEIVLKEKENELK 943
Query: 267 -LKNNLKEQDKRIENLREKVNILEAQNKELKTQV---------ALSSETPRTKVSKAVST 316
L+ LKE++ + + + + ++ +NK K+Q+ SS P ++ K +S
Sbjct: 944 RLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISE 1003
Query: 317 SELKTEGV 324
E + G+
Sbjct: 1004 REKEISGL 1011
Score = 46.6 bits (109), Expect = 3e-05
Identities = 65/314 (20%), Positives = 140/314 (44%), Gaps = 42/314 (13%)
Query: 45 QKIRTQMFKDEIRHDSTNHKLDAKHCG--NLQQGSDSEMDPSCCSLDLLMKKIKGKDLQL 102
+++++ + K H++ L +K N Q S++ + S L +++ +QL
Sbjct: 498 EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRL----MQL 553
Query: 103 LE-----MNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
+E +NKE E L++++Q E A L+ Q+ Q+ +E K +
Sbjct: 554 MESEQKRVNKE-ESLQMQVQDILEQNEA-LKAQIQQFHSQIAAQTSASVLAEELHKVIA- 610
Query: 158 VNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENL--VQRMEKEKRTLLERKLSLENK 215
EK++++KQ ++L ++L K ++ +++N+ + + E +K L + +
Sbjct: 611 ----EKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAH 666
Query: 216 LLQLKSSATYGKSC------QDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGL-- 267
L+ + Y K + LQ EIS E+ +++ Q++ L+S +Q+++ L
Sbjct: 667 ELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK----ILNDQNKALKSEVQKLQTLVS 722
Query: 268 ----KNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSE------TPRTKVSKAVSTS 317
K+ +++ +K I+ EK+ +E + QVA E T + ++K V
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 318 ELKTEGVSPYLMLI 331
+ K + L+
Sbjct: 783 KAKQNDQVSFASLV 796
Score = 37.0 bits (84), Expect = 0.025
Identities = 59/275 (21%), Positives = 114/275 (41%), Gaps = 54/275 (19%)
Query: 38 KKIRTTLQKIRTQMFKDEIRH------------DSTNHKLDAKHCGNLQQGSDSEMDPSC 85
++++ Q++R QM + EI H +T ++L++K L + D +
Sbjct: 402 QQMQMKFQQVREQM-EAEIAHLKQENGILRDAVSNTTNQLESKQSAELNK---LRQDYAR 457
Query: 86 CSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV 145
+L K K + ++ + N E ++K+Q A+R +E Q+ +
Sbjct: 458 LVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQE----------AERRWEEVQSYIRKR 507
Query: 146 RKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTL 205
+ E ++Q LQ + KE ++ + HS++T+ Q++E+ L
Sbjct: 508 TAEHEAAQQDLQSKFVAKENEV--------------QSLHSKLTDTLVSKQQLEQRLMQL 553
Query: 206 LERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEME 265
+E + NK L+ QD+ + L+ QI HSQ S E
Sbjct: 554 MESEQKRVNKEESLQMQV------QDILEQNEALKAQIQQ----FHSQIAAQTSASVLAE 603
Query: 266 GLKNNLKEQDKRI----ENLREKVNILEAQNKELK 296
L + E+DK+I ++L + + L ++ +ELK
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
Score = 37.0 bits (84), Expect = 0.025
Identities = 47/228 (20%), Positives = 106/228 (46%), Gaps = 20/228 (8%)
Query: 106 NKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQ 165
++E +VL+ KL+ + E + + Q E Y++ V + E Q LQ + ++E
Sbjct: 1112 SEEVKVLEHKLKEADE-----MHTLLQLECEKYKS----VLAETEGILQKLQRSVEQEEN 1162
Query: 166 KLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSS--- 222
K K V+ ++ ++++ S T E ++R+ E + + + E+ ++L+ +
Sbjct: 1163 KWKVKVDESHKTIKQMQ---SSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEME 1219
Query: 223 -ATYGKSCQDLQREISILQEQI--SHLQFVIHSQHQNL--RSVIQEMEGLKNNLKEQDKR 277
+TY ++L+ ++ LQ+++ S+ + V ++ NL + + + L+ E+ K
Sbjct: 1220 RSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKV 1279
Query: 278 IENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTEGVS 325
+L + LE ++ ++ + VS +SE +T VS
Sbjct: 1280 AGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVS 1327
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 60.8 bits (146), Expect = 2e-09
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 27/258 (10%)
Query: 88 LDLLMKKIKGKDLQLLEMNKENEVLK-----IKLQASREAGAAALRNVAQRLFENYQTQS 142
L+ + K+ K+ + ++ +E + LK ++L+ +++ + Q L + + Q
Sbjct: 817 LEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQM 876
Query: 143 EEVRKK-QEDSKQLLQVNKL-----EKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQ 196
++ +E K L K E+ + LK HV+ + Q K SQ ELE +++
Sbjct: 877 NTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLK 936
Query: 197 RMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQ--- 253
E E + L E+ L SS T + QD+Q E + + QI L+ + Q
Sbjct: 937 EKENELKRLEAMLKERESDL----SSKT--QLLQDVQDENKLFKSQIEQLKQQNYQQASS 990
Query: 254 ---HQNLRSVIQEME----GLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETP 306
H+ L VI E E GL N L +E+ R+K N L +N E +A + +
Sbjct: 991 FPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKML 1050
Query: 307 RTKVSKAVSTSELKTEGV 324
+ KV+K + + E V
Sbjct: 1051 QDKVNKTSKERQQQVEAV 1068
Score = 49.7 bits (117), Expect = 4e-06
Identities = 83/368 (22%), Positives = 161/368 (43%), Gaps = 84/368 (22%)
Query: 24 ESTSAHIIEETE---YVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSE 80
++ +AH +E+ + YVK KIR + +++++H+ +N + K + + SE
Sbjct: 661 QAAAAHELEKMQQSVYVKD-----DKIR--LLEEQLQHEISNKMEEFKILNDQNKALKSE 713
Query: 81 MD---------PSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVA 131
+ P+ ++ + K I+ KD +L + + E I++ A++E A+R
Sbjct: 714 VQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQV-ATKEEELNAIRTEN 772
Query: 132 QRLFENYQTQSEEVRKKQEDSKQLLQVNKL--EKEQKLK-----------------QHVE 172
L + Q + + + + ++ K+ EK+ K+K + V+
Sbjct: 773 SSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQ 832
Query: 173 NLNQVAEKLEEK--------------HSQITELENLVQRMEKEKRTLLERKLSLENKLLQ 218
+L Q + L+E+ S++ EL+NL++ E++ T+ K LE K
Sbjct: 833 DLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTM---KAVLEEK--- 886
Query: 219 LKSSATYGKSCQDLQREISILQEQISHLQFVIH---------SQHQNLRSVIQEMEG--- 266
K A GK QDLQ E L+ +H+Q V SQ + L V++E E
Sbjct: 887 EKDLANTGKWLQDLQEENESLK---AHVQEVAQHNLKEASSASQFEELEIVLKEKENELK 943
Query: 267 -LKNNLKEQDKRIENLREKVNILEAQNKELKTQV---------ALSSETPRTKVSKAVST 316
L+ LKE++ + + + + ++ +NK K+Q+ SS P ++ K +S
Sbjct: 944 RLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISE 1003
Query: 317 SELKTEGV 324
E + G+
Sbjct: 1004 REKEISGL 1011
Score = 46.6 bits (109), Expect = 3e-05
Identities = 65/314 (20%), Positives = 140/314 (44%), Gaps = 42/314 (13%)
Query: 45 QKIRTQMFKDEIRHDSTNHKLDAKHCG--NLQQGSDSEMDPSCCSLDLLMKKIKGKDLQL 102
+++++ + K H++ L +K N Q S++ + S L +++ +QL
Sbjct: 498 EEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRL----MQL 553
Query: 103 LE-----MNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
+E +NKE E L++++Q E A L+ Q+ Q+ +E K +
Sbjct: 554 MESEQKRVNKE-ESLQMQVQDILEQNEA-LKAQIQQFHSQIAAQTSASVLAEELHKVIA- 610
Query: 158 VNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENL--VQRMEKEKRTLLERKLSLENK 215
EK++++KQ ++L ++L K ++ +++N+ + + E +K L + +
Sbjct: 611 ----EKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAH 666
Query: 216 LLQLKSSATYGKSC------QDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGL-- 267
L+ + Y K + LQ EIS E+ +++ Q++ L+S +Q+++ L
Sbjct: 667 ELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK----ILNDQNKALKSEVQKLQTLVS 722
Query: 268 ----KNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSE------TPRTKVSKAVSTS 317
K+ +++ +K I+ EK+ +E + QVA E T + ++K V
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 318 ELKTEGVSPYLMLI 331
+ K + L+
Sbjct: 783 KAKQNDQVSFASLV 796
Score = 37.0 bits (84), Expect = 0.025
Identities = 59/275 (21%), Positives = 114/275 (41%), Gaps = 54/275 (19%)
Query: 38 KKIRTTLQKIRTQMFKDEIRH------------DSTNHKLDAKHCGNLQQGSDSEMDPSC 85
++++ Q++R QM + EI H +T ++L++K L + D +
Sbjct: 402 QQMQMKFQQVREQM-EAEIAHLKQENGILRDAVSNTTNQLESKQSAELNK---LRQDYAR 457
Query: 86 CSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV 145
+L K K + ++ + N E ++K+Q A+R +E Q+ +
Sbjct: 458 LVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQE----------AERRWEEVQSYIRKR 507
Query: 146 RKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTL 205
+ E ++Q LQ + KE ++ + HS++T+ Q++E+ L
Sbjct: 508 TAEHEAAQQDLQSKFVAKENEV--------------QSLHSKLTDTLVSKQQLEQRLMQL 553
Query: 206 LERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEME 265
+E + NK L+ QD+ + L+ QI HSQ S E
Sbjct: 554 MESEQKRVNKEESLQMQV------QDILEQNEALKAQIQQ----FHSQIAAQTSASVLAE 603
Query: 266 GLKNNLKEQDKRI----ENLREKVNILEAQNKELK 296
L + E+DK+I ++L + + L ++ +ELK
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
Score = 37.0 bits (84), Expect = 0.025
Identities = 47/228 (20%), Positives = 106/228 (46%), Gaps = 20/228 (8%)
Query: 106 NKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQ 165
++E +VL+ KL+ + E + + Q E Y++ V + E Q LQ + ++E
Sbjct: 1112 SEEVKVLEHKLKEADE-----MHTLLQLECEKYKS----VLAETEGILQKLQRSVEQEEN 1162
Query: 166 KLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSS--- 222
K K V+ ++ ++++ S T E ++R+ E + + + E+ ++L+ +
Sbjct: 1163 KWKVKVDESHKTIKQMQ---SSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEME 1219
Query: 223 -ATYGKSCQDLQREISILQEQI--SHLQFVIHSQHQNL--RSVIQEMEGLKNNLKEQDKR 277
+TY ++L+ ++ LQ+++ S+ + V ++ NL + + + L+ E+ K
Sbjct: 1220 RSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKV 1279
Query: 278 IENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTEGVS 325
+L + LE ++ ++ + VS +SE +T VS
Sbjct: 1280 AGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVS 1327
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 60.8 bits (146), Expect = 2e-09
Identities = 64/258 (24%), Positives = 117/258 (45%), Gaps = 53/258 (20%)
Query: 92 MKKIKGK-DLQLLEMNKENEVLKIKLQASREAGAAALRNVAQ--------------RLFE 136
+KKIK L+L +N E L+ ++ A A A +N+ +
Sbjct: 1462 LKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQ 1521
Query: 137 NYQTQSEEVRKKQEDS-KQLLQVNKLEKE-----QKLKQHVENLNQVAEKLEEKHSQITE 190
Q +S+ ++++ E S +QLLQ K EKE Q+L + +E N+ AE L++K ++T
Sbjct: 1522 ICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTR 1581
Query: 191 LEN----LVQRMEKEKRTLLERKLSLENKLLQLKSSA---------------TYGKSCQD 231
N ++QR++ E ++ K +++ + LK A K+ QD
Sbjct: 1582 QNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQD 1641
Query: 232 LQREISILQEQISHLQFVIHSQH----------QNLRSVIQEMEGLKNNLKEQDKRIENL 281
QR+I L+E ++ Q ++ QN + ++ + N KE+ +R E
Sbjct: 1642 FQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGE-- 1699
Query: 282 REKVNILEAQNKELKTQV 299
+KV + +AQ +EL ++
Sbjct: 1700 -QKVQLQQAQVQELNNRL 1716
Score = 45.8 bits (107), Expect = 5e-05
Identities = 65/305 (21%), Positives = 134/305 (43%), Gaps = 25/305 (8%)
Query: 1 MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS 60
+ T+T + + K +S++ II+E ++ T L + TQ K
Sbjct: 1041 LQTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLK 1100
Query: 61 TNHKLDAKHCGNLQQ-GSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQAS 119
+ + K C + G+ S++ + L K+ GK +L E V ++K Q S
Sbjct: 1101 RLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISEL-----ERMVAELKKQKS 1155
Query: 120 REAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAE 179
R V + L + + E+RK+Q + + + + K+ E + KQ+ L +
Sbjct: 1156 R---------VEEELPKVREAAENELRKQQRNVEDI-SLQKIRAESEAKQYRRELETIVR 1205
Query: 180 KLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQD-LQRE--- 235
+ E ++ + L E ++ + E L+ N QL+ + ++ +D L+R+
Sbjct: 1206 EKEAAERELERVRQLTIEAEAKRAAVEENLLNFRN---QLEENTFTRRTLEDHLKRKDLS 1262
Query: 236 ISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIE-NLREKVNI-LEAQNK 293
++ L++Q + L + + N +++ ++ ++ +L Q + E L+EK I LEA+ K
Sbjct: 1263 LNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRK 1322
Query: 294 ELKTQ 298
+ Q
Sbjct: 1323 ITEIQ 1327
Score = 45.1 bits (105), Expect = 9e-05
Identities = 59/310 (19%), Positives = 136/310 (43%), Gaps = 44/310 (14%)
Query: 13 RDKME-DNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLD-AKHC 70
RD+ E + + + S H+ E+ E K LQ I+ + ++ + N +L+ + C
Sbjct: 1512 RDEKELERLQICQRKSDHLKEQFE--KSHEQLLQNIKAEKENND-KIQRLNEELEKSNEC 1568
Query: 71 GNLQQGSDSEMDPSCCSLDLLMKKIKGKD----LQLLEMNKENEVLKIKLQASREAGAAA 126
+ + E+ L+M++I+ + L+ + + E LKI+ ++
Sbjct: 1569 AEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQ---- 1624
Query: 127 LRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKE------------QKLKQHVENL 174
LR+ + L + +T+ + RK + + L + L E Q K+ V NL
Sbjct: 1625 LRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNL 1684
Query: 175 N-----------QVAEKLEEKHSQITELENLVQRMEKEKRT-LLERKLSLENKLLQLKSS 222
N + +K++ + +Q+ EL N +++++ E +E +++ +L + S
Sbjct: 1685 NAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEES 1744
Query: 223 ATYGKSCQDLQREISILQEQ-------ISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQD 275
+ +S ++ ++++ L E IS ++ S Q + + + N+KE +
Sbjct: 1745 GKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELE 1804
Query: 276 KRIENLREKV 285
++++ RE++
Sbjct: 1805 RQLQQYREQM 1814
Score = 40.8 bits (94), Expect = 0.002
Identities = 46/243 (18%), Positives = 95/243 (39%), Gaps = 35/243 (14%)
Query: 92 MKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQED 151
+++ K K ++ L ++NE +KL E A + VA++ + Q E R+K +
Sbjct: 1266 LEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITE 1325
Query: 152 SKQLLQVNKL-----------------------EKEQKLKQHVENLNQVAEKLEEKHSQI 188
+ + N L +K ++LKQ V+ L K E+ ++
Sbjct: 1326 IQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMREL 1385
Query: 189 TELENLVQ---RMEKEKRTLLERKLSLENKLLQL---------KSSATYGKSCQDLQREI 236
T N +Q +EK LL+ KL N L+ ++ Y + ++L R++
Sbjct: 1386 TYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQL 1445
Query: 237 SILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELK 296
+ + + R+ E+E L + + + ++ + + E + L
Sbjct: 1446 NQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLN 1505
Query: 297 TQV 299
+Q+
Sbjct: 1506 SQI 1508
Score = 32.3 bits (72), Expect = 0.61
Identities = 40/201 (19%), Positives = 79/201 (39%), Gaps = 47/201 (23%)
Query: 63 HKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREA 122
H+L++++ L + E LD L + +L+ +N++ E + R
Sbjct: 352 HRLESQYAKLLNTSRNQERH-----LDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNT 406
Query: 123 GAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNK--------------------LE 162
A ++ L + E ++ QE ++QLL N L+
Sbjct: 407 NIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQ 466
Query: 163 KEQKLKQHVEN-----------------LNQVAEKLEEKHS-----QITELENLVQRMEK 200
Q ++QH++ L + + ++ K+S I +LE+LVQ +
Sbjct: 467 LCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESME 526
Query: 201 EKRTLLERKLSLENKLLQLKS 221
EK LL+ K ++ N + + K+
Sbjct: 527 EKEELLQYKSTIANLMGKAKT 547
Score = 32.0 bits (71), Expect = 0.80
Identities = 29/98 (29%), Positives = 55/98 (56%), Gaps = 13/98 (13%)
Query: 137 NYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQ----------VAEKLEEKH- 185
++ + +E + QE++K L + N E E++L+Q+ E + Q +KLE++
Sbjct: 1778 DFVSLQQENSRAQENAK-LCETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELI 1836
Query: 186 SQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSA 223
+Q E+ENL Q+M+++ + E +L L +Q KS+A
Sbjct: 1837 AQKREVENLKQKMDQQIKE-HEHQLVLLQCEIQKKSTA 1873
Score = 30.0 bits (66), Expect = 3.0
Identities = 34/161 (21%), Positives = 71/161 (44%), Gaps = 10/161 (6%)
Query: 109 NEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLK 168
N V ++++Q R + L +V L EN++ + + + K+ ++++++ LK
Sbjct: 287 NWVDEMQVQLDRTEWGSDLPSVESHL-ENHKNVHRAIEEFESSLKEA-KISEIQMTAPLK 344
Query: 169 QHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKS 228
AEKL SQ +L N + E+ TL N+L+ L +
Sbjct: 345 L------TYAEKLHRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVA 398
Query: 229 CQDLQREISILQEQISHLQFV--IHSQHQNLRSVIQEMEGL 267
+R +I +++ H + + + + +N++SV + E L
Sbjct: 399 YDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQL 439
Score = 30.0 bits (66), Expect = 3.0
Identities = 40/190 (21%), Positives = 82/190 (43%), Gaps = 20/190 (10%)
Query: 127 LRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVE----NLNQVAEKLE 182
+RN+ RL ++R E V ++ +++KLK+ +E +L + K E
Sbjct: 746 VRNIRLRLENCEDRLIRQIRTPLERDDLHESVFRITEQEKLKKELERLKDDLGTITNKCE 805
Query: 183 EKHSQITELENLVQRMEKEKRTLLE---RKLSLENKLL-QLKSSATYGKSCQDLQREISI 238
E SQ + V + E +L+ + S+ + + +LK+ K+ Q + + +
Sbjct: 806 EFFSQ-AAASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLKTVNLVLKNTQAAEALVKL 864
Query: 239 LQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
+ ++ + VI ++ +E L + LK+ ++ EK + A EL+
Sbjct: 865 YETKLCEEEAVIADKN--------NIENLISTLKQWRSEVD---EKRQVFHALEDELQKA 913
Query: 299 VALSSETPRT 308
A+S E +T
Sbjct: 914 KAISDEMFKT 923
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 60.5 bits (145), Expect = 2e-09
Identities = 64/260 (24%), Positives = 117/260 (45%), Gaps = 38/260 (14%)
Query: 98 KDLQLLEMN-KENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLL 156
+D+Q L+ + +E E L + E+ L +V + E +Q + ++V +K L
Sbjct: 620 RDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVT--IMERFQMELKDVERKIAQQAAKL 677
Query: 157 Q-------VNKLEKEQKLKQHVENLNQVAEKLE-------EKHSQITELENLVQRMEKEK 202
Q V ++ +E++ KQH L+ V+ K+E ++ QI L++ ++ EK
Sbjct: 678 QGIDLDRTVQQVNQEKQEKQH--KLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEK 735
Query: 203 ---RTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRS 259
T L+R+ LE + ++L + Q L REI +EQ+S L+ + Q
Sbjct: 736 LQISTNLQRRQQLEEQTVELSTEV------QSLYREIKDAKEQVSPLETTLEKFQQEKEE 789
Query: 260 VIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL-------KTQVALSSETPRTKVSK 312
+I + +N QDK + +++EKV + K++ K ET KV
Sbjct: 790 LINKKN--TSNKIAQDK-LNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIA 846
Query: 313 AVSTSELKTEGVSPYLMLIR 332
+S E E ++ + L+R
Sbjct: 847 QLSECEKHKEKINEDMRLMR 866
Score = 41.6 bits (96), Expect = 0.001
Identities = 70/335 (20%), Positives = 144/335 (42%), Gaps = 55/335 (16%)
Query: 33 ETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLM 92
+++ + + R L K+ ++ E + N++L K L D D C S D
Sbjct: 444 KSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKE-EQLSSYEDKLFDV-CGSQDF-- 499
Query: 93 KKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRN--VAQRLFEN----------YQT 140
DL L+ E+ K Q + AGA A+ + + Q EN +QT
Sbjct: 500 ----ESDLDRLK----EEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQT 551
Query: 141 QSE------EVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK---LEEKHSQITEL 191
++E +++ K + L+ + E ++K K+ E L V + ++ K +I EL
Sbjct: 552 EAELQEVISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPEL 611
Query: 192 ENLVQRMEKEKRTL---LERKLSLENKLLQLKSSAT-----------YGKSCQDLQREIS 237
N +Q + ++ + L +E + +L ++ + SA + +D++R+I+
Sbjct: 612 RNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIA 671
Query: 238 ILQEQISHLQFV-----IHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQN 292
+Q + LQ + + +Q + +++ + + ++ K I++ +E++ L++
Sbjct: 672 ---QQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTT 728
Query: 293 KELKTQVALSSETPRTKVSKAVSTSELKTEGVSPY 327
ELK++ S + + T EL TE S Y
Sbjct: 729 NELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLY 763
Score = 38.9 bits (89), Expect = 0.007
Identities = 59/297 (19%), Positives = 130/297 (43%), Gaps = 44/297 (14%)
Query: 6 VTTEIPPRDKMEDN----SALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDST 61
++T + R ++E+ S +S I + E V + TTL+K + + ++ I +T
Sbjct: 738 ISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEK-EELINKKNT 796
Query: 62 NHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIK-----GKDLQLLEMNKENEVLKIKL 116
++K+ Q +++ ++ MK I+ GKD + KE E+ K+
Sbjct: 797 SNKI--------AQDKLNDIKEKVKNIHGYMKDIENYIQDGKDDY--KKQKETELNKVIA 846
Query: 117 QAS-----REAGAAALRNV-----AQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQK 166
Q S +E +R + Q++ E + + +RK+ E+ K E E++
Sbjct: 847 QLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEELK--------EVEEE 898
Query: 167 LKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSS--AT 224
KQH++ + Q+ ++ + S+ +LE + +++ L R+ E +++ K
Sbjct: 899 RKQHLKEMGQM--QVLQMKSEHQKLEENIDNIKRNHNLALGRQKGYEEEIIHFKKELREP 956
Query: 225 YGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENL 281
+ ++ RE+ I+ + + ++ L I + +K ++E +K I +L
Sbjct: 957 QFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMK--MEEINKIIRDL 1011
Score = 38.1 bits (87), Expect = 0.011
Identities = 39/198 (19%), Positives = 88/198 (44%), Gaps = 25/198 (12%)
Query: 139 QTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRM 198
QTQ ++V++ Q + K L KQ+ E ++ +++ K +Q+T + +V+
Sbjct: 58 QTQGQKVKEYQMELKYL------------KQYKEKACEIRDQITSKEAQLTSSKEIVKSY 105
Query: 199 EKEKRTLLERKLSLENKLLQLKSSATYGKSC----QDLQREISILQEQI--------SHL 246
E E L R +E+ L ++ K+ + ++++ S L+E++ L
Sbjct: 106 ENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQL 165
Query: 247 QFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETP 306
+ H+ + +R +++ L++ +K L ++ + L + L+ Q E
Sbjct: 166 NDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHI 225
Query: 307 RTKVSKAVS-TSELKTEG 323
R + S S ++L+ +G
Sbjct: 226 RARDSLIQSLATQLELDG 243
Score = 37.7 bits (86), Expect = 0.015
Identities = 49/243 (20%), Positives = 107/243 (44%), Gaps = 25/243 (10%)
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEM--------NKENEVLKIKLQASREAGAAA 126
Q +++D + LD M+++ +M +K+ ++ KIK + S E +
Sbjct: 369 QNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLL 428
Query: 127 LRNVAQRLFENY-QTQSEEVRKKQEDSKQL------LQVNKLEKEQKLKQHVENLNQVAE 179
++ E++ ++S+E+ + ++ +L + NK +LK+ E L+ +
Sbjct: 429 GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYED 488
Query: 180 KL------EEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKS-SATYGKSCQDL 232
KL ++ S + L+ +++ K++ L + QL + + CQ +
Sbjct: 489 KLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRV 548
Query: 233 QREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQN 292
+ + LQE IS LQ + L+S E LK K +D+ + + + +I++ +
Sbjct: 549 FQTEAELQEVISDLQSKLRLAPDKLKSTESE---LKKKEKRRDEMLGLVPMRQSIIDLKE 605
Query: 293 KEL 295
KE+
Sbjct: 606 KEI 608
Score = 37.4 bits (85), Expect = 0.019
Identities = 64/281 (22%), Positives = 114/281 (40%), Gaps = 43/281 (15%)
Query: 53 KDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKG-KDLQLLEMNKENEV 111
K EI N + K+ +GS + L+L + IK ++L E N E
Sbjct: 307 KSEILSKKQNELKNVKYELQQLEGSSDRI------LELDQELIKAERELSKAEKNSNVET 360
Query: 112 LK---IKLQASREAGAAALRNVAQRLFE-NYQT---------------QSEEVRK-KQED 151
LK I LQ + LR + Q + + N+ T + E++RK K
Sbjct: 361 LKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRH 420
Query: 152 SKQLLQV-----NKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLL 206
S +L + NK + E L + +NQ ++L + + ++ E + E +
Sbjct: 421 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKE 480
Query: 207 ERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHL--------QFV--IHSQHQN 256
E+ S E+KL + S + L+ EI +Q + L QF+ + ++Q+
Sbjct: 481 EQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQS 540
Query: 257 LRSVIQEMEGLKNNLKEQDKRIEN-LREKVNILEAQNKELK 296
V Q + + L+E +++ LR + L++ ELK
Sbjct: 541 CCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELK 581
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 60.5 bits (145), Expect = 2e-09
Identities = 64/260 (24%), Positives = 117/260 (45%), Gaps = 38/260 (14%)
Query: 98 KDLQLLEMN-KENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLL 156
+D+Q L+ + +E E L + E+ L +V + E +Q + ++V +K L
Sbjct: 759 RDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVT--IMERFQMELKDVERKIAQQAAKL 816
Query: 157 Q-------VNKLEKEQKLKQHVENLNQVAEKLE-------EKHSQITELENLVQRMEKEK 202
Q V ++ +E++ KQH L+ V+ K+E ++ QI L++ ++ EK
Sbjct: 817 QGIDLDRTVQQVNQEKQEKQH--KLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEK 874
Query: 203 ---RTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRS 259
T L+R+ LE + ++L + Q L REI +EQ+S L+ + Q
Sbjct: 875 LQISTNLQRRQQLEEQTVELSTEV------QSLYREIKDAKEQVSPLETTLEKFQQEKEE 928
Query: 260 VIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL-------KTQVALSSETPRTKVSK 312
+I + +N QDK + +++EKV + K++ K ET KV
Sbjct: 929 LINKKN--TSNKIAQDK-LNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIA 985
Query: 313 AVSTSELKTEGVSPYLMLIR 332
+S E E ++ + L+R
Sbjct: 986 QLSECEKHKEKINEDMRLMR 1005
Score = 41.6 bits (96), Expect = 0.001
Identities = 70/335 (20%), Positives = 144/335 (42%), Gaps = 55/335 (16%)
Query: 33 ETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLM 92
+++ + + R L K+ ++ E + N++L K L D D C S D
Sbjct: 583 KSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKE-EQLSSYEDKLFDV-CGSQDF-- 638
Query: 93 KKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRN--VAQRLFEN----------YQT 140
DL L+ E+ K Q + AGA A+ + + Q EN +QT
Sbjct: 639 ----ESDLDRLK----EEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQT 690
Query: 141 QSE------EVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK---LEEKHSQITEL 191
++E +++ K + L+ + E ++K K+ E L V + ++ K +I EL
Sbjct: 691 EAELQEVISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPEL 750
Query: 192 ENLVQRMEKEKRTL---LERKLSLENKLLQLKSSAT-----------YGKSCQDLQREIS 237
N +Q + ++ + L +E + +L ++ + SA + +D++R+I+
Sbjct: 751 RNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIA 810
Query: 238 ILQEQISHLQFV-----IHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQN 292
+Q + LQ + + +Q + +++ + + ++ K I++ +E++ L++
Sbjct: 811 ---QQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTT 867
Query: 293 KELKTQVALSSETPRTKVSKAVSTSELKTEGVSPY 327
ELK++ S + + T EL TE S Y
Sbjct: 868 NELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLY 902
Score = 38.9 bits (89), Expect = 0.007
Identities = 59/297 (19%), Positives = 130/297 (43%), Gaps = 44/297 (14%)
Query: 6 VTTEIPPRDKMEDN----SALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDST 61
++T + R ++E+ S +S I + E V + TTL+K + + ++ I +T
Sbjct: 877 ISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEK-EELINKKNT 935
Query: 62 NHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIK-----GKDLQLLEMNKENEVLKIKL 116
++K+ Q +++ ++ MK I+ GKD + KE E+ K+
Sbjct: 936 SNKI--------AQDKLNDIKEKVKNIHGYMKDIENYIQDGKDDY--KKQKETELNKVIA 985
Query: 117 QAS-----REAGAAALRNV-----AQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQK 166
Q S +E +R + Q++ E + + +RK+ E+ K E E++
Sbjct: 986 QLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEELK--------EVEEE 1037
Query: 167 LKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSS--AT 224
KQH++ + Q+ ++ + S+ +LE + +++ L R+ E +++ K
Sbjct: 1038 RKQHLKEMGQM--QVLQMKSEHQKLEENIDNIKRNHNLALGRQKGYEEEIIHFKKELREP 1095
Query: 225 YGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENL 281
+ ++ RE+ I+ + + ++ L I + +K ++E +K I +L
Sbjct: 1096 QFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMK--MEEINKIIRDL 1150
Score = 38.1 bits (87), Expect = 0.011
Identities = 39/198 (19%), Positives = 88/198 (44%), Gaps = 25/198 (12%)
Query: 139 QTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRM 198
QTQ ++V++ Q + K L KQ+ E ++ +++ K +Q+T + +V+
Sbjct: 197 QTQGQKVKEYQMELKYL------------KQYKEKACEIRDQITSKEAQLTSSKEIVKSY 244
Query: 199 EKEKRTLLERKLSLENKLLQLKSSATYGKSC----QDLQREISILQEQI--------SHL 246
E E L R +E+ L ++ K+ + ++++ S L+E++ L
Sbjct: 245 ENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQL 304
Query: 247 QFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETP 306
+ H+ + +R +++ L++ +K L ++ + L + L+ Q E
Sbjct: 305 NDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHI 364
Query: 307 RTKVSKAVS-TSELKTEG 323
R + S S ++L+ +G
Sbjct: 365 RARDSLIQSLATQLELDG 382
Score = 37.7 bits (86), Expect = 0.015
Identities = 49/243 (20%), Positives = 107/243 (44%), Gaps = 25/243 (10%)
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEM--------NKENEVLKIKLQASREAGAAA 126
Q +++D + LD M+++ +M +K+ ++ KIK + S E +
Sbjct: 508 QNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLL 567
Query: 127 LRNVAQRLFENY-QTQSEEVRKKQEDSKQL------LQVNKLEKEQKLKQHVENLNQVAE 179
++ E++ ++S+E+ + ++ +L + NK +LK+ E L+ +
Sbjct: 568 GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYED 627
Query: 180 KL------EEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKS-SATYGKSCQDL 232
KL ++ S + L+ +++ K++ L + QL + + CQ +
Sbjct: 628 KLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRV 687
Query: 233 QREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQN 292
+ + LQE IS LQ + L+S E LK K +D+ + + + +I++ +
Sbjct: 688 FQTEAELQEVISDLQSKLRLAPDKLKSTESE---LKKKEKRRDEMLGLVPMRQSIIDLKE 744
Query: 293 KEL 295
KE+
Sbjct: 745 KEI 747
Score = 37.4 bits (85), Expect = 0.019
Identities = 64/281 (22%), Positives = 114/281 (40%), Gaps = 43/281 (15%)
Query: 53 KDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKG-KDLQLLEMNKENEV 111
K EI N + K+ +GS + L+L + IK ++L E N E
Sbjct: 446 KSEILSKKQNELKNVKYELQQLEGSSDRI------LELDQELIKAERELSKAEKNSNVET 499
Query: 112 LK---IKLQASREAGAAALRNVAQRLFE-NYQT---------------QSEEVRK-KQED 151
LK I LQ + LR + Q + + N+ T + E++RK K
Sbjct: 500 LKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRH 559
Query: 152 SKQLLQV-----NKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLL 206
S +L + NK + E L + +NQ ++L + + ++ E + E +
Sbjct: 560 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKE 619
Query: 207 ERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHL--------QFV--IHSQHQN 256
E+ S E+KL + S + L+ EI +Q + L QF+ + ++Q+
Sbjct: 620 EQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQS 679
Query: 257 LRSVIQEMEGLKNNLKEQDKRIEN-LREKVNILEAQNKELK 296
V Q + + L+E +++ LR + L++ ELK
Sbjct: 680 CCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELK 720
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 60.1 bits (144), Expect = 3e-09
Identities = 68/325 (20%), Positives = 150/325 (46%), Gaps = 40/325 (12%)
Query: 16 MEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLD--AKHCGNL 73
+++ + +Y + + EE + RT L+ + Q+ ++ S + + D A L
Sbjct: 343 LQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRL 402
Query: 74 QQGSDSEMDPSCCSLDLLMKK---IKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNV 130
++ ++ LL +K I+ +D L E N+E +++ + A+A ++
Sbjct: 403 EEKHEA----------LLKEKERLIEQRDT-LKETNEELRCSQVQQDHLNQTDASATKSY 451
Query: 131 AQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITE 190
E + EV + + ++L++ + E E + ++ E+LE+KH ++ E
Sbjct: 452 ENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSEN------ERIEELQEQLEQKHRKMNE 505
Query: 191 LENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVI 250
LE QR+ KE+ L++++ K LQ + S + G+S L++++ E+++ +
Sbjct: 506 LET-EQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTE----V 560
Query: 251 HSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKV 310
H + Q + +I++++ N +N+ +K+N LEA ++ + E + +
Sbjct: 561 HEELQKKQELIEDLQPDIN---------QNV-QKINELEAALQKKDEDMKAMEERYKMYL 610
Query: 311 SKA---VSTSELKTEGVSPYLMLIR 332
KA + T + K S +ML+R
Sbjct: 611 EKARNVIKTLDPKLNPASAEIMLLR 635
Score = 49.7 bits (117), Expect = 4e-06
Identities = 56/281 (19%), Positives = 119/281 (42%), Gaps = 32/281 (11%)
Query: 42 TTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQ 101
TTLQ + + + ++ N KLD Q S DP+ ++ KK LQ
Sbjct: 209 TTLQDEKNSLVSE---NEMMNEKLD--------QLDGSFDDPNT----VVAKKYFHAQLQ 253
Query: 102 LLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKL 161
L ++ +EN +L+A+++ + ++L E +Q +++E+ E+++ L +++
Sbjct: 254 LEQLQEEN----FRLEAAKDDYRVHCEELEKQLIE-FQHRNDELTSLAEETRALK--DEI 306
Query: 162 EKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKS 221
+ + L E +K + +L V+ +++ + +SLE +L + +
Sbjct: 307 DVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANA 366
Query: 222 SATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENL 281
+ T ++ + Q+ L + S+ + ++ EM+ L+ + K E L
Sbjct: 367 ART----------QLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERL 416
Query: 282 REKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
E+ + L+ N+EL+ +T S S L E
Sbjct: 417 IEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAE 457
Score = 47.0 bits (110), Expect = 2e-05
Identities = 67/305 (21%), Positives = 137/305 (44%), Gaps = 28/305 (9%)
Query: 4 VTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNH 63
V +++E D + E +++E E + + R TL++ ++ +++ D N
Sbjct: 383 VKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLN- 441
Query: 64 KLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAG 123
+ DA + + + +E+ P + + + K L+L + ENE ++ +LQ E
Sbjct: 442 QTDASATKSYENLA-AEIMPVEYREVFIRLQHENKMLRLQQEGSENERIE-ELQEQLEQK 499
Query: 124 AAALRNVA--QRL----FENYQTQSEEVRKK-QEDSKQLLQVNKLEKEQKLKQHVENLNQ 176
+ + QRL Q Q E+++K QE + + + +QKL+ H+E L +
Sbjct: 500 HRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTE 559
Query: 177 VAEKLEEKHSQITELE-NLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQRE 235
V E+L++K I +L+ ++ Q ++K + E + +L+ K +K+ K + R
Sbjct: 560 VHEELQKKQELIEDLQPDINQNVQK----INELEAALQKKDEDMKAMEERYKMYLEKARN 615
Query: 236 ISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL 295
VI + L E+ L+ L E+++RIE L + + + ++ E
Sbjct: 616 -------------VIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEE 662
Query: 296 KTQVA 300
K V+
Sbjct: 663 KLIVS 667
Score = 43.5 bits (101), Expect = 3e-04
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 32/168 (19%)
Query: 162 EKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKS 221
E EQ+LK+ +E L + + EE + EL+ V ++ EK +L+ + KL QL
Sbjct: 175 ELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDG 234
Query: 222 S-----ATYGKSCQDLQREISILQEQISHLQF---------------VIHSQHQN--LRS 259
S K Q ++ LQE+ L+ +I QH+N L S
Sbjct: 235 SFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTS 294
Query: 260 VIQEMEGLKNNL----------KEQDKRIENLREKVNILEAQNKELKT 297
+ +E LK+ + + + +E R+K+ L K++KT
Sbjct: 295 LAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKT 342
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 59.3 bits (142), Expect = 5e-09
Identities = 62/300 (20%), Positives = 146/300 (48%), Gaps = 35/300 (11%)
Query: 43 TLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQL 102
TLQ+ TQ+ +++++ S +HK ++ + Q + + + + L + + QL
Sbjct: 572 TLQEQVTQL-TEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQL 630
Query: 103 LEMNKENEVLKIKLQASREAGAAA-LRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKL 161
E ++ L I+++A E +A AQR +++ + ++ LQ
Sbjct: 631 NESKEKVSQLDIQIKAKTELLLSAEAAKTAQRA---------DLQNHLDTAQNALQ---- 677
Query: 162 EKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKS 221
+K+Q+L + L+QV KL++K ++LE+ ++ +++ +L ++ LE ++ +L++
Sbjct: 678 DKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEA 737
Query: 222 -----SATYGKSCQDLQREISI----------LQEQISHLQFVIHSQHQNLRSVIQEMEG 266
A+ ++ QDLQ++ + L +Q+ + ++ S +L+ + +E
Sbjct: 738 DSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797
Query: 267 LKNNLKEQDKRIENLREKVNIL----EAQNKELKTQVALS-SETPRTKVSKAVSTSELKT 321
+K L +Q++ + L++ L + Q++EL ++ + +E + K+ K +EL T
Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELST 857
Score = 59.3 bits (142), Expect = 5e-09
Identities = 80/366 (21%), Positives = 164/366 (44%), Gaps = 65/366 (17%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTL--QKIRTQMFKDEIRHDSTNHKLDAKHCGN 72
++E + ST + +++E ++ I+ L Q+ Q+ K + S K+ + N
Sbjct: 773 QLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN 832
Query: 73 LQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAA------ 126
Q + +E+ + LM ++ +L +++ + K + + + G AA
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Query: 127 ----LRNVAQRLFENYQTQSEEVRKKQEDSK---------------QLLQV-NKLEKEQK 166
L++ Q EN + +E++K E K QL+Q N L++ +K
Sbjct: 893 TCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEK 952
Query: 167 LKQHVE-NLNQVAEKLEEKHSQI--------------TELENLVQRM----------EKE 201
+Q ++ N+N++ + E+K QI TELEN +Q+ EKE
Sbjct: 953 EEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKE 1012
Query: 202 KRTLLERKLSLENKLLQLKSSATYGKSCQDL--QREISILQEQISHLQ-FVIHSQHQ--N 256
K ++L+ + + S YG+ + L ++++ ++E++S Q +I +++Q N
Sbjct: 1013 KISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGN 1072
Query: 257 LRSVIQEMEGLKNNLKEQD--KRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAV 314
+IQE++ K L EQD K+ + L+E+ L+ +++ + +L + + SK
Sbjct: 1073 QNKLIQELKTAKATL-EQDSAKKEQQLQERCKALQ----DIQKEKSLKEKELVNEKSKLA 1127
Query: 315 STSELK 320
E+K
Sbjct: 1128 EIEEIK 1133
Score = 55.1 bits (131), Expect = 9e-08
Identities = 56/281 (19%), Positives = 132/281 (46%), Gaps = 24/281 (8%)
Query: 32 EETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSE-MDPSCCSLDL 90
EE+ K I+ TL + + + R ++ L H ++G ++ + ++
Sbjct: 327 EESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVET 386
Query: 91 LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQE 150
+ +K + QL + +E E ++LQ+ + + +L E + Q E + +
Sbjct: 387 KYQHLKAEFKQLQQQREEKEQHGLQLQSE-------INQLHSKLLET-ERQLGEAHGRLK 438
Query: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKL 210
+ +QL ++KEQ++ L+++ E+L+EK + TEL++ + + +++ +
Sbjct: 439 EQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ------- 491
Query: 211 SLENKLLQLKSSATYGKSCQDLQ---REISILQEQISHLQFVIHSQHQNLRSVIQEMEGL 267
E + LQ ++A ++ DL+ R+I ++I +L+ ++ +N+ + +E E L
Sbjct: 492 --EQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDL 549
Query: 268 KNNLKEQDKR---IENLREKVNILEAQNKELKTQVALSSET 305
++ + + L+EK + L+ Q +L ++ SE+
Sbjct: 550 YAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES 590
Score = 53.5 bits (127), Expect = 3e-07
Identities = 77/311 (24%), Positives = 136/311 (43%), Gaps = 48/311 (15%)
Query: 26 TSAHII-----EETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSE 80
TS H I E+ E +K++ L ++ T+ + + + K LQ S+
Sbjct: 358 TSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSE-- 415
Query: 81 MDPSCCSLDLLMKKIKGKDLQLLEMN---KENEVLKIKLQASREAGAAALRNVAQRLFEN 137
++ L K+ + QL E + KE L + +E A L+ RL E
Sbjct: 416 -------INQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQ 468
Query: 138 YQ---TQSEEVRKKQEDSKQLLQVNKLEKEQ---KLKQHVENLNQVAEKLEEKHSQITEL 191
+ T S E++ + + +KQ Q + ++ KL++ +L QV ++ +K +I L
Sbjct: 469 LKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNL 528
Query: 192 ENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSC--QDLQREISILQEQISHLQFV 249
E L+Q+ KE +LLE+ E + L K A G++ LQ + LQEQ++ L
Sbjct: 529 EALLQK-SKENISLLEK----EREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLT-- 581
Query: 250 IHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTK 309
E LKN + + ENL ++V +A + + +V LS ET +
Sbjct: 582 ---------------EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV-LSLETSVNE 625
Query: 310 VSKAVSTSELK 320
++ ++ S+ K
Sbjct: 626 LNSQLNESKEK 636
Score = 50.1 bits (118), Expect = 3e-06
Identities = 68/321 (21%), Positives = 134/321 (41%), Gaps = 47/321 (14%)
Query: 6 VTTEIPP-RDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHK 64
+ TEI + K ++ +L E+ + TE + K T +Q ++T++ + D K
Sbjct: 168 LATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLK 227
Query: 65 LDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGA 124
+ L D LE +E+E LK + + + A
Sbjct: 228 KELVQVQTLM------------------------DNMTLERERESEKLKDECKKLQSQYA 263
Query: 125 AALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKL-EKEQKLKQHVENLNQVAEKLEE 183
++ ++Q E + E QE K VN+L +K Q L +++ Q KLEE
Sbjct: 264 SSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEE 323
Query: 184 KHSQITELENLVQRMEKEK----RTLLERKLSLENKLLQLK-SSATYGKSCQDLQREISI 238
KH++ + + +Q +K + L R + E L ++ + G++ Q L+ E+S
Sbjct: 324 KHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSE 383
Query: 239 LQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
++ + HL+ E + L+ +E+++ L+ ++N + +K L+T+
Sbjct: 384 VETKYQHLK--------------AEFKQLQQQREEKEQHGLQLQSEIN--QLHSKLLETE 427
Query: 299 VALSSETPRTKVSKAVSTSEL 319
L R K + +S+ +L
Sbjct: 428 RQLGEAHGRLKEQRQLSSEKL 448
Score = 48.5 bits (114), Expect = 8e-06
Identities = 57/286 (19%), Positives = 122/286 (42%), Gaps = 30/286 (10%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+++ A E SA ++ + K +QK ++ K+ + S +++ C
Sbjct: 1079 ELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKC---- 1134
Query: 75 QGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRL 134
+ L+ +K K + ++ + K+ + L I+ + + A +L+ ++
Sbjct: 1135 -----RQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQE 1189
Query: 135 FENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHS----QITE 190
N Q ++V+K++E+ K+ +EKE KL ++ +K EE + QIT
Sbjct: 1190 KRNQQILKDQVKKEEEELKK----EFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITA 1245
Query: 191 LENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVI 250
L + ++KE ++ R LE K DL+ EI++L+ + + Q
Sbjct: 1246 LNENLGTVKKEWQSSQRRVSELE-------------KQTDDLRGEIAVLEATVQNNQDER 1292
Query: 251 HSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELK 296
+ + E+E L+ + E ++++N V L +N+ L+
Sbjct: 1293 RALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQ 1338
Score = 45.8 bits (107), Expect = 5e-05
Identities = 62/290 (21%), Positives = 132/290 (45%), Gaps = 41/290 (14%)
Query: 50 QMFKD-EIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKE 108
++FK E HD+ N D+ H G +S + + LL ++++ L E
Sbjct: 55 ELFKHYEAVHDAGN---DSGH------GGESNLALKRDDVTLLRQEVQDLQASLKEEKWY 105
Query: 109 NEVLKIKLQA-----SREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQV----- 158
+E LK +L+ +EA L + ++ + Q EE + + + KQ+ +
Sbjct: 106 SEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKA 165
Query: 159 -----------NKLEKEQKLKQHVEN-LNQVAEKLEEKHSQITELEN-LVQRMEKE---- 201
+K ++E+ L++ E + ++ E+L ++ + I +L+ L+QR E
Sbjct: 166 AQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAV 225
Query: 202 -KRTLLERKLSLENKLLQL-KSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRS 259
K+ L++ + ++N L+ + S C+ LQ + + + IS L+ + Q +
Sbjct: 226 LKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAV 285
Query: 260 VIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTK 309
+QE++ LK+++ E ++ + L E N+L+ + K + + E+ K
Sbjct: 286 YVQELQKLKSSVNELTQKNQTLTE--NLLKKEQDYTKLEEKHNEESVSKK 333
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 58.9 bits (141), Expect = 6e-09
Identities = 62/297 (20%), Positives = 123/297 (41%), Gaps = 40/297 (13%)
Query: 16 MEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQ 75
+ D + E + + E KK T QK+ M + + ++T+ L +H +L
Sbjct: 1155 LADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSL-- 1212
Query: 76 GSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLF 135
+E++ +L + +K++ KD L++ ++ + +++ +A A ++L
Sbjct: 1213 ---AELEGQVENLQQVKQKLE-KDKSDLQLEVDDLLTRVEQMTRAKANA-------EKLC 1261
Query: 136 ENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLV 195
Y+ + E K + QL +K + + E L ++ EK E L+
Sbjct: 1262 TLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK-----------EALI 1310
Query: 196 QRMEKEKRTLLERKLSLENKL-LQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQH 254
++ +EK + L +L + KS + + Q QR+ +L+EQ Q V H
Sbjct: 1311 NQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELH 1370
Query: 255 QNL---------------RSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELK 296
+ L +VIQ E L++ KE R++ E + + A+N L+
Sbjct: 1371 RTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLE 1427
Score = 52.0 bits (123), Expect = 7e-07
Identities = 67/300 (22%), Positives = 140/300 (46%), Gaps = 53/300 (17%)
Query: 27 SAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCC 86
S+ + EE +K+ LQK + K E + + +L AK Q+ +D
Sbjct: 854 SSEVGEEVAGLKEECAQLQKA---LEKSEFQRE----ELKAKQVSLTQEKND-------- 898
Query: 87 SLDLLMKKIKGKDLQLLEMNKENE-VLKIKLQASREAGAAALRNVAQRLFENYQTQSE-- 143
L+ +++ + L + ++ E ++K K+Q A ++ +++R+ E + SE
Sbjct: 899 ----LILQLQAEQETLANVEEQCEWLIKSKIQLE-----ARVKELSERVEEEEEINSELT 949
Query: 144 -----------EVRKKQEDSKQLLQVNKLEKEQKLKQH-VENLNQVAEKLEEKHSQITEL 191
E++K+ +D + +L K EKE++ +H V+NL + E L E S++
Sbjct: 950 ARGRKLEDECFELKKEIDDLETMLV--KSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRA 1007
Query: 192 ENLVQR----------MEKEKRTLLER-KLSLENKLLQLKSSATYGKSCQ-DLQREISIL 239
+VQ ME+EK + L + L LE ++ +L+ + + + + +RE+ L
Sbjct: 1008 AKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKL 1067
Query: 240 QEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
+ + + + + + R + +E+ + L + + ++EN + V L+ KEL+TQ+
Sbjct: 1068 EGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQI 1127
Score = 47.8 bits (112), Expect = 1e-05
Identities = 61/282 (21%), Positives = 127/282 (45%), Gaps = 48/282 (17%)
Query: 27 SAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSD-SEMDPSC 85
++ + E V +++ T+++++TQ+ KD KL+A+ + + +++
Sbjct: 1103 NSKVENEKGLVAQLQKTVKELQTQI-KD------LKEKLEAERTTRAKMERERADLTQDL 1155
Query: 86 CSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV 145
L+ ++++ G L LE+ K+ E KL E +++T S +
Sbjct: 1156 ADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATL-----------HFETTSASL 1204
Query: 146 RKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQI-TELENLVQRMEKEKRT 204
+K+ DS +L+ VENL QV +KLE+ S + E+++L+ R+E+
Sbjct: 1205 KKRHADSLA-----------ELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQ---- 1249
Query: 205 LLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEM 264
+ R + KL L + + + +++ L ++ + + S+ ++E
Sbjct: 1250 -MTRAKANAEKLCTLYEERLHEATAK--LDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306
Query: 265 EGLKNNLKEQ----DKRIENLREKVNILEAQNKELKTQVALS 302
E L N L + ++IE+LR ++ KE K+Q AL+
Sbjct: 1307 EALINQLSREKSNFTRQIEDLRGQL------EKETKSQSALA 1342
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/195 (20%), Positives = 86/195 (44%), Gaps = 23/195 (11%)
Query: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVE----NLNQ 176
EA A ++ A+ + + Q E+ +K ++ L + +L+K+Q H+E N+ Q
Sbjct: 1743 EADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSE--ELKKKQDTIAHLERTRENMEQ 1800
Query: 177 VAEKLEEK------------HSQITELENLVQRMEKEKRTLLERKLSLENKLLQLK---S 221
L+++ QI +LE+ V+ +E E + R + +L+
Sbjct: 1801 TITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK 1860
Query: 222 SATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENL 281
TY ++ ++ +S +Q Q+ LQ + + Q + + + K+Q + +
Sbjct: 1861 ELTY--QAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEV 1918
Query: 282 REKVNILEAQNKELK 296
+E+ + E+Q +LK
Sbjct: 1919 KERAEVAESQVNKLK 1933
Score = 45.1 bits (105), Expect = 9e-05
Identities = 51/249 (20%), Positives = 115/249 (46%), Gaps = 26/249 (10%)
Query: 88 LDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRK 147
LD K+++ +LL++ E + G LR + L E + +VR+
Sbjct: 1479 LDASQKEVQALSTELLKLKNTYEESIV--------GQETLRRENKNLQEEISNLTNQVRE 1530
Query: 148 KQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELE-NLVQRMEKEKRTLL 206
++ ++ +V KL +E+K + V L + LE S+I + L++ + +R L
Sbjct: 1531 GTKNLTEMEKVKKLIEEEKTEVQV-TLEETEGALERNESKILHFQLELLEAKAELERKLS 1589
Query: 207 ERKLSLEN-------KLLQLKSSA-TYGKSCQDLQREISILQEQISHLQFVIHSQHQNLR 258
E+ +EN + L+SS + KS ++ R ++E ++ ++ + ++ +
Sbjct: 1590 EKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVS 1649
Query: 259 SVIQEMEGLKNNLKEQDKRIE-------NLREKVNILEAQNKELKTQVA-LSSETPRTKV 310
+ + L+ +K+ +++ +L+E+V + E +N L++++ L S +T+
Sbjct: 1650 EATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTER 1709
Query: 311 SKAVSTSEL 319
+ +S EL
Sbjct: 1710 GRRLSEEEL 1718
Score = 40.0 bits (92), Expect = 0.003
Identities = 57/264 (21%), Positives = 122/264 (46%), Gaps = 38/264 (14%)
Query: 24 ESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMDP 83
+ T A++ E+ E++ K + L+ ++ + + N +L A+ +++
Sbjct: 907 QETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTAR---------GRKLED 957
Query: 84 SCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSE 143
C L K+I + L++ KE + K++ E + L E+ +
Sbjct: 958 ECFELK---KEIDDLETMLVKSEKEKRTTEHKVKNLTEE--------VEFLNEDISKLNR 1006
Query: 144 EVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKR 203
+ QE +Q L +E+E+ + +L++ KLE+ Q+ ELE +++ E++ R
Sbjct: 1007 AAKVVQEAHQQTLDDLHMEEEK-----LSSLSKANLKLEQ---QVDELEGALEQ-ERKAR 1057
Query: 204 TLLERKL-SLENKL-LQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVI 261
ER+L LE L L +S S + L E+ + ++S + +S+ +N + ++
Sbjct: 1058 MNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQM----NSKVENEKGLV 1113
Query: 262 QEMEGLKNNLKEQDKRIENLREKV 285
+ L+ +KE +I++L+EK+
Sbjct: 1114 AQ---LQKTVKELQTQIKDLKEKL 1134
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/233 (23%), Positives = 106/233 (45%), Gaps = 27/233 (11%)
Query: 93 KKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLF--ENYQTQSEEVRKKQE 150
KK+ + L L E +E E + KLQ + A ++ + + ++ + + RK E
Sbjct: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Query: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKH-SQITELENLVQRMEKEKRTLLERK 209
+ L N E+E+K K NL KL+ KH S I+ELE +++ EK ++ L + K
Sbjct: 1006 ERISDLTTNLAEEEEKAK----NLT----KLKNKHESMISELEVRLKKEEKSRQELEKLK 1057
Query: 210 LSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKN 269
LE D +I+ LQ QI+ L+ + + + L++ + ++ +
Sbjct: 1058 RKLEG-------------DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD---D 1101
Query: 270 NLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
+ +++ ++ +RE + ++L ++ A ++ + K LKTE
Sbjct: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154
Score = 53.9 bits (128), Expect = 2e-07
Identities = 65/331 (19%), Positives = 147/331 (44%), Gaps = 45/331 (13%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+MED + + ++ E + + + T +++++TQ+ +E+ + LQ
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL--EELEDE-------------LQ 1556
Query: 75 QGSDSEMDPSCCSLDLLMKKIKG---KDLQLLEMNKENEVLKIKLQA-----------SR 120
D+++ L++ M+ +KG +DLQ + E + +++ Q +
Sbjct: 1557 ATEDAKL-----RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611
Query: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDS-KQL--LQVNKLEKEQKLKQHVENLNQV 177
A AAA + + ++ + Q++ K +E++ KQL LQ + +++L+ + +++
Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEI 1671
Query: 178 AEKLEEKHSQITELENLVQRMEKE----KRTLLERKLSLENKLLQLKSSATYGKSCQD-- 231
+E + LE + +++++ +R + L E +L SS + + QD
Sbjct: 1672 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1731
Query: 232 --LQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILE 289
L+ I+ L+E++ Q + + +R Q+ E L N L + + LE
Sbjct: 1732 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1791
Query: 290 AQNKELKTQVALSSETPRTKVSKAVSTSELK 320
QNKEL++++ ++K ++ E K
Sbjct: 1792 RQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/228 (23%), Positives = 109/228 (47%), Gaps = 32/228 (14%)
Query: 100 LQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVN 159
LQ+ +E + + +LQ ++E Q+ EN + E+ + + K LLQ
Sbjct: 845 LQVTRQEEEMQAKEDELQKTKER---------QQKAENELKELEQKHSQLTEEKNLLQ-E 894
Query: 160 KLEKEQKLKQHVENL--------NQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLS 211
+L+ E +L E + ++ E L E +++ E E+ Q+++ E++ + ++ L
Sbjct: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
Query: 212 LENKLLQLKSSATYGKSCQDLQREISILQEQISHLQ---FVIHSQHQNL---RSVIQE-M 264
LE +L + +++ Q LQ E + +I L+ V+ Q+ L R +++E +
Sbjct: 955 LEEQLEEEEAAR------QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008
Query: 265 EGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
L NL E++++ +NL + N E+ EL+ ++ E R ++ K
Sbjct: 1009 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK-KEEKSRQELEK 1055
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/204 (24%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 153 KQLLQVNKLEKE--------QKLKQHVENLNQVAEKLEEKHSQITELENLVQRM------ 198
K LLQV + E+E QK K+ + ++LE+KHSQ+TE +NL+Q
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 199 -----EKEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQISHLQFVIHS 252
E+ + L +K LE L ++++ + Q LQ E + +Q+ L+ +
Sbjct: 902 LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 961
Query: 253 QHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
+ + + E + +K+ + I + ++ N L + K L+ +++ + + K
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Query: 313 AVSTSELKTEGVSPYLML-IRLRK 335
A + ++LK + S L +RL+K
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKK 1045
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/202 (20%), Positives = 89/202 (44%), Gaps = 14/202 (6%)
Query: 104 EMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV-----RKKQEDSKQLLQV 158
E K+ + L+ L +E AAA R Q E + E R +D K+ L+
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1736
Query: 159 NKLEKEQKLKQHVENLNQVAEKLEEKHSQITELEN--LVQRMEKEKRTLLERKLSLENKL 216
+ E++L++ N+ +++++ + Q +L N +R +K ++L +NK
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Query: 217 LQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDK 276
L+ K G + I+ L+ +I+ L+ + + +E + +LK++DK
Sbjct: 1797 LRSKLHEMEGAVKSKFKSTIAALEAKIAQLE-------EQVEQEAREKQAATKSLKQKDK 1849
Query: 277 RIENLREKVNILEAQNKELKTQ 298
+++ + +V ++ K Q
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQ 1871
Score = 45.8 bits (107), Expect = 5e-05
Identities = 67/342 (19%), Positives = 144/342 (42%), Gaps = 33/342 (9%)
Query: 6 VTTEIPPRDKMEDNSALYESTSAHIIEETEY----VKKIRTTLQKIRTQMFKD------- 54
+TT + ++ N ++ +I E E +K R L+K++ ++ D
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 55 --EIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKE---- 108
+++ K+ Q + + +D + +KKI+ + + ++ ++
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 109 ----NEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKE 164
N+ K K E AL+ + ++ TQ +E+R K+E +L+ E+
Sbjct: 1131 RAARNKAEKQKRDLGEEL--EALKTELEDTLDSTATQ-QELRAKREQEVTVLKKALDEET 1187
Query: 165 QKLKQHVENLNQV-AEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLL---QLK 220
+ + V+ + Q A+ +EE Q+ + + ++K K+TL + L +L Q K
Sbjct: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1247
Query: 221 SSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN 280
+ K + L+ ++ LQ + S + + + + E+E + L E + +
Sbjct: 1248 QEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 281 LREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
L + V L +Q ++ TQ L ET R K++ + +L+ E
Sbjct: 1306 LAKDVASLSSQLQD--TQELLQEET-RQKLNVSTKLRQLEEE 1344
Score = 37.7 bits (86), Expect = 0.015
Identities = 49/215 (22%), Positives = 98/215 (45%), Gaps = 32/215 (14%)
Query: 91 LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR---NVAQRLFENYQTQSEEVRK 147
++ + +GK ++L K+ L +LQ ++E R NV+ +L Q EE R
Sbjct: 1295 MLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQKLNVSTKL-----RQLEEERN 1346
Query: 148 KQEDSKQLLQVNKLEKEQKLKQHVENLN----QVAEKLEEKHSQITELENLVQRMEKEKR 203
+D ++E +Q L++H+ LN +KL++ S + LE +R +KE
Sbjct: 1347 SLQDQLD----EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIE 1402
Query: 204 TLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQE 263
L ++ E K +A Y K L++ + LQ+++ L + +Q Q + ++ ++
Sbjct: 1403 NLTQQ---YEEK------AAAYDK----LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 264 MEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
L E+ ++ + EA+ +E +T+
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/233 (23%), Positives = 106/233 (45%), Gaps = 27/233 (11%)
Query: 93 KKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLF--ENYQTQSEEVRKKQE 150
KK+ + L L E +E E + KLQ + A ++ + + ++ + + RK E
Sbjct: 953 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Query: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKH-SQITELENLVQRMEKEKRTLLERK 209
+ L N E+E+K K NL KL+ KH S I+ELE +++ EK ++ L + K
Sbjct: 1013 ERISDLTTNLAEEEEKAK----NLT----KLKNKHESMISELEVRLKKEEKSRQELEKLK 1064
Query: 210 LSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKN 269
LE D +I+ LQ QI+ L+ + + + L++ + ++ +
Sbjct: 1065 RKLEG-------------DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD---D 1108
Query: 270 NLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
+ +++ ++ +RE + ++L ++ A ++ + K LKTE
Sbjct: 1109 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1161
Score = 53.9 bits (128), Expect = 2e-07
Identities = 65/331 (19%), Positives = 147/331 (44%), Gaps = 45/331 (13%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+MED + + ++ E + + + T +++++TQ+ +E+ + LQ
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL--EELEDE-------------LQ 1563
Query: 75 QGSDSEMDPSCCSLDLLMKKIKG---KDLQLLEMNKENEVLKIKLQA-----------SR 120
D+++ L++ M+ +KG +DLQ + E + +++ Q +
Sbjct: 1564 ATEDAKL-----RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618
Query: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDS-KQL--LQVNKLEKEQKLKQHVENLNQV 177
A AAA + + ++ + Q++ K +E++ KQL LQ + +++L+ + +++
Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEI 1678
Query: 178 AEKLEEKHSQITELENLVQRMEKE----KRTLLERKLSLENKLLQLKSSATYGKSCQD-- 231
+E + LE + +++++ +R + L E +L SS + + QD
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1738
Query: 232 --LQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILE 289
L+ I+ L+E++ Q + + +R Q+ E L N L + + LE
Sbjct: 1739 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1798
Query: 290 AQNKELKTQVALSSETPRTKVSKAVSTSELK 320
QNKEL++++ ++K ++ E K
Sbjct: 1799 RQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1829
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/228 (23%), Positives = 109/228 (47%), Gaps = 32/228 (14%)
Query: 100 LQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVN 159
LQ+ +E + + +LQ ++E Q+ EN + E+ + + K LLQ
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKER---------QQKAENELKELEQKHSQLTEEKNLLQ-E 901
Query: 160 KLEKEQKLKQHVENL--------NQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLS 211
+L+ E +L E + ++ E L E +++ E E+ Q+++ E++ + ++ L
Sbjct: 902 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 961
Query: 212 LENKLLQLKSSATYGKSCQDLQREISILQEQISHLQ---FVIHSQHQNL---RSVIQE-M 264
LE +L + +++ Q LQ E + +I L+ V+ Q+ L R +++E +
Sbjct: 962 LEEQLEEEEAAR------QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1015
Query: 265 EGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
L NL E++++ +NL + N E+ EL+ ++ E R ++ K
Sbjct: 1016 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK-KEEKSRQELEK 1062
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/204 (24%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 153 KQLLQVNKLEKE--------QKLKQHVENLNQVAEKLEEKHSQITELENLVQRM------ 198
K LLQV + E+E QK K+ + ++LE+KHSQ+TE +NL+Q
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 908
Query: 199 -----EKEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQISHLQFVIHS 252
E+ + L +K LE L ++++ + Q LQ E + +Q+ L+ +
Sbjct: 909 LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 968
Query: 253 QHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
+ + + E + +K+ + I + ++ N L + K L+ +++ + + K
Sbjct: 969 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Query: 313 AVSTSELKTEGVSPYLML-IRLRK 335
A + ++LK + S L +RL+K
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKK 1052
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/202 (20%), Positives = 89/202 (44%), Gaps = 14/202 (6%)
Query: 104 EMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV-----RKKQEDSKQLLQV 158
E K+ + L+ L +E AAA R Q E + E R +D K+ L+
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1743
Query: 159 NKLEKEQKLKQHVENLNQVAEKLEEKHSQITELEN--LVQRMEKEKRTLLERKLSLENKL 216
+ E++L++ N+ +++++ + Q +L N +R +K ++L +NK
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Query: 217 LQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDK 276
L+ K G + I+ L+ +I+ L+ + + +E + +LK++DK
Sbjct: 1804 LRSKLHEMEGAVKSKFKSTIAALEAKIAQLE-------EQVEQEAREKQAATKSLKQKDK 1856
Query: 277 RIENLREKVNILEAQNKELKTQ 298
+++ + +V ++ K Q
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQ 1878
Score = 45.8 bits (107), Expect = 5e-05
Identities = 67/342 (19%), Positives = 144/342 (42%), Gaps = 33/342 (9%)
Query: 6 VTTEIPPRDKMEDNSALYESTSAHIIEETEY----VKKIRTTLQKIRTQMFKD------- 54
+TT + ++ N ++ +I E E +K R L+K++ ++ D
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 55 --EIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKE---- 108
+++ K+ Q + + +D + +KKI+ + + ++ ++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 109 ----NEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKE 164
N+ K K E AL+ + ++ TQ +E+R K+E +L+ E+
Sbjct: 1138 RAARNKAEKQKRDLGEEL--EALKTELEDTLDSTATQ-QELRAKREQEVTVLKKALDEET 1194
Query: 165 QKLKQHVENLNQV-AEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLL---QLK 220
+ + V+ + Q A+ +EE Q+ + + ++K K+TL + L +L Q K
Sbjct: 1195 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1254
Query: 221 SSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN 280
+ K + L+ ++ LQ + S + + + + E+E + L E + +
Sbjct: 1255 QEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 281 LREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
L + V L +Q ++ TQ L ET R K++ + +L+ E
Sbjct: 1313 LAKDVASLSSQLQD--TQELLQEET-RQKLNVSTKLRQLEEE 1351
Score = 37.7 bits (86), Expect = 0.015
Identities = 49/215 (22%), Positives = 98/215 (45%), Gaps = 32/215 (14%)
Query: 91 LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR---NVAQRLFENYQTQSEEVRK 147
++ + +GK ++L K+ L +LQ ++E R NV+ +L Q EE R
Sbjct: 1302 MLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQKLNVSTKL-----RQLEEERN 1353
Query: 148 KQEDSKQLLQVNKLEKEQKLKQHVENLN----QVAEKLEEKHSQITELENLVQRMEKEKR 203
+D ++E +Q L++H+ LN +KL++ S + LE +R +KE
Sbjct: 1354 SLQDQLD----EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIE 1409
Query: 204 TLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQE 263
L ++ E K +A Y K L++ + LQ+++ L + +Q Q + ++ ++
Sbjct: 1410 NLTQQ---YEEK------AAAYDK----LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Query: 264 MEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
L E+ ++ + EA+ +E +T+
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/233 (23%), Positives = 106/233 (45%), Gaps = 27/233 (11%)
Query: 93 KKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLF--ENYQTQSEEVRKKQE 150
KK+ + L L E +E E + KLQ + A ++ + + ++ + + RK E
Sbjct: 953 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Query: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKH-SQITELENLVQRMEKEKRTLLERK 209
+ L N E+E+K K NL KL+ KH S I+ELE +++ EK ++ L + K
Sbjct: 1013 ERISDLTTNLAEEEEKAK----NLT----KLKNKHESMISELEVRLKKEEKSRQELEKLK 1064
Query: 210 LSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKN 269
LE D +I+ LQ QI+ L+ + + + L++ + ++ +
Sbjct: 1065 RKLEG-------------DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD---D 1108
Query: 270 NLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
+ +++ ++ +RE + ++L ++ A ++ + K LKTE
Sbjct: 1109 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1161
Score = 53.9 bits (128), Expect = 2e-07
Identities = 65/331 (19%), Positives = 147/331 (44%), Gaps = 45/331 (13%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+MED + + ++ E + + + T +++++TQ+ +E+ + LQ
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL--EELEDE-------------LQ 1563
Query: 75 QGSDSEMDPSCCSLDLLMKKIKG---KDLQLLEMNKENEVLKIKLQA-----------SR 120
D+++ L++ M+ +KG +DLQ + E + +++ Q +
Sbjct: 1564 ATEDAKL-----RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618
Query: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDS-KQL--LQVNKLEKEQKLKQHVENLNQV 177
A AAA + + ++ + Q++ K +E++ KQL LQ + +++L+ + +++
Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEI 1678
Query: 178 AEKLEEKHSQITELENLVQRMEKE----KRTLLERKLSLENKLLQLKSSATYGKSCQD-- 231
+E + LE + +++++ +R + L E +L SS + + QD
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1738
Query: 232 --LQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILE 289
L+ I+ L+E++ Q + + +R Q+ E L N L + + LE
Sbjct: 1739 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1798
Query: 290 AQNKELKTQVALSSETPRTKVSKAVSTSELK 320
QNKEL++++ ++K ++ E K
Sbjct: 1799 RQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1829
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/228 (23%), Positives = 109/228 (47%), Gaps = 32/228 (14%)
Query: 100 LQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVN 159
LQ+ +E + + +LQ ++E Q+ EN + E+ + + K LLQ
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKER---------QQKAENELKELEQKHSQLTEEKNLLQ-E 901
Query: 160 KLEKEQKLKQHVENL--------NQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLS 211
+L+ E +L E + ++ E L E +++ E E+ Q+++ E++ + ++ L
Sbjct: 902 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 961
Query: 212 LENKLLQLKSSATYGKSCQDLQREISILQEQISHLQ---FVIHSQHQNL---RSVIQE-M 264
LE +L + +++ Q LQ E + +I L+ V+ Q+ L R +++E +
Sbjct: 962 LEEQLEEEEAAR------QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1015
Query: 265 EGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
L NL E++++ +NL + N E+ EL+ ++ E R ++ K
Sbjct: 1016 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK-KEEKSRQELEK 1062
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/204 (24%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 153 KQLLQVNKLEKE--------QKLKQHVENLNQVAEKLEEKHSQITELENLVQRM------ 198
K LLQV + E+E QK K+ + ++LE+KHSQ+TE +NL+Q
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 908
Query: 199 -----EKEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQISHLQFVIHS 252
E+ + L +K LE L ++++ + Q LQ E + +Q+ L+ +
Sbjct: 909 LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 968
Query: 253 QHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
+ + + E + +K+ + I + ++ N L + K L+ +++ + + K
Sbjct: 969 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Query: 313 AVSTSELKTEGVSPYLML-IRLRK 335
A + ++LK + S L +RL+K
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKK 1052
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/202 (20%), Positives = 89/202 (44%), Gaps = 14/202 (6%)
Query: 104 EMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV-----RKKQEDSKQLLQV 158
E K+ + L+ L +E AAA R Q E + E R +D K+ L+
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1743
Query: 159 NKLEKEQKLKQHVENLNQVAEKLEEKHSQITELEN--LVQRMEKEKRTLLERKLSLENKL 216
+ E++L++ N+ +++++ + Q +L N +R +K ++L +NK
Sbjct: 1744 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Query: 217 LQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDK 276
L+ K G + I+ L+ +I+ L+ + + +E + +LK++DK
Sbjct: 1804 LRSKLHEMEGAVKSKFKSTIAALEAKIAQLE-------EQVEQEAREKQAATKSLKQKDK 1856
Query: 277 RIENLREKVNILEAQNKELKTQ 298
+++ + +V ++ K Q
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQ 1878
Score = 45.8 bits (107), Expect = 5e-05
Identities = 67/342 (19%), Positives = 144/342 (42%), Gaps = 33/342 (9%)
Query: 6 VTTEIPPRDKMEDNSALYESTSAHIIEETEY----VKKIRTTLQKIRTQMFKD------- 54
+TT + ++ N ++ +I E E +K R L+K++ ++ D
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 55 --EIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKE---- 108
+++ K+ Q + + +D + +KKI+ + + ++ ++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 109 ----NEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKE 164
N+ K K E AL+ + ++ TQ +E+R K+E +L+ E+
Sbjct: 1138 RAARNKAEKQKRDLGEEL--EALKTELEDTLDSTATQ-QELRAKREQEVTVLKKALDEET 1194
Query: 165 QKLKQHVENLNQV-AEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLL---QLK 220
+ + V+ + Q A+ +EE Q+ + + ++K K+TL + L +L Q K
Sbjct: 1195 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1254
Query: 221 SSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN 280
+ K + L+ ++ LQ + S + + + + E+E + L E + +
Sbjct: 1255 QEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 281 LREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
L + V L +Q ++ TQ L ET R K++ + +L+ E
Sbjct: 1313 LAKDVASLSSQLQD--TQELLQEET-RQKLNVSTKLRQLEEE 1351
Score = 37.7 bits (86), Expect = 0.015
Identities = 49/215 (22%), Positives = 98/215 (45%), Gaps = 32/215 (14%)
Query: 91 LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR---NVAQRLFENYQTQSEEVRK 147
++ + +GK ++L K+ L +LQ ++E R NV+ +L Q EE R
Sbjct: 1302 MLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQKLNVSTKL-----RQLEEERN 1353
Query: 148 KQEDSKQLLQVNKLEKEQKLKQHVENLN----QVAEKLEEKHSQITELENLVQRMEKEKR 203
+D ++E +Q L++H+ LN +KL++ S + LE +R +KE
Sbjct: 1354 SLQDQLD----EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIE 1409
Query: 204 TLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQE 263
L ++ E K +A Y K L++ + LQ+++ L + +Q Q + ++ ++
Sbjct: 1410 NLTQQ---YEEK------AAAYDK----LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Query: 264 MEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
L E+ ++ + EA+ +E +T+
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/233 (23%), Positives = 106/233 (45%), Gaps = 27/233 (11%)
Query: 93 KKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLF--ENYQTQSEEVRKKQE 150
KK+ + L L E +E E + KLQ + A ++ + + ++ + + RK E
Sbjct: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Query: 151 DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKH-SQITELENLVQRMEKEKRTLLERK 209
+ L N E+E+K K NL KL+ KH S I+ELE +++ EK ++ L + K
Sbjct: 1006 ERISDLTTNLAEEEEKAK----NLT----KLKNKHESMISELEVRLKKEEKSRQELEKLK 1057
Query: 210 LSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKN 269
LE D +I+ LQ QI+ L+ + + + L++ + ++ +
Sbjct: 1058 RKLEG-------------DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD---D 1101
Query: 270 NLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
+ +++ ++ +RE + ++L ++ A ++ + K LKTE
Sbjct: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154
Score = 53.9 bits (128), Expect = 2e-07
Identities = 65/331 (19%), Positives = 147/331 (44%), Gaps = 45/331 (13%)
Query: 15 KMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQ 74
+MED + + ++ E + + + T +++++TQ+ +E+ + LQ
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL--EELEDE-------------LQ 1556
Query: 75 QGSDSEMDPSCCSLDLLMKKIKG---KDLQLLEMNKENEVLKIKLQA-----------SR 120
D+++ L++ M+ +KG +DLQ + E + +++ Q +
Sbjct: 1557 ATEDAKL-----RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611
Query: 121 EAGAAALRNVAQRLFENYQTQSEEVRKKQEDS-KQL--LQVNKLEKEQKLKQHVENLNQV 177
A AAA + + ++ + Q++ K +E++ KQL LQ + +++L+ + +++
Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEI 1671
Query: 178 AEKLEEKHSQITELENLVQRMEKE----KRTLLERKLSLENKLLQLKSSATYGKSCQD-- 231
+E + LE + +++++ +R + L E +L SS + + QD
Sbjct: 1672 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1731
Query: 232 --LQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILE 289
L+ I+ L+E++ Q + + +R Q+ E L N L + + LE
Sbjct: 1732 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1791
Query: 290 AQNKELKTQVALSSETPRTKVSKAVSTSELK 320
QNKEL++++ ++K ++ E K
Sbjct: 1792 RQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/228 (23%), Positives = 109/228 (47%), Gaps = 32/228 (14%)
Query: 100 LQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVN 159
LQ+ +E + + +LQ ++E Q+ EN + E+ + + K LLQ
Sbjct: 845 LQVTRQEEEMQAKEDELQKTKER---------QQKAENELKELEQKHSQLTEEKNLLQ-E 894
Query: 160 KLEKEQKLKQHVENL--------NQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLS 211
+L+ E +L E + ++ E L E +++ E E+ Q+++ E++ + ++ L
Sbjct: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
Query: 212 LENKLLQLKSSATYGKSCQDLQREISILQEQISHLQ---FVIHSQHQNL---RSVIQE-M 264
LE +L + +++ Q LQ E + +I L+ V+ Q+ L R +++E +
Sbjct: 955 LEEQLEEEEAAR------QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008
Query: 265 EGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
L NL E++++ +NL + N E+ EL+ ++ E R ++ K
Sbjct: 1009 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK-KEEKSRQELEK 1055
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/204 (24%), Positives = 95/204 (46%), Gaps = 21/204 (10%)
Query: 153 KQLLQVNKLEKE--------QKLKQHVENLNQVAEKLEEKHSQITELENLVQRM------ 198
K LLQV + E+E QK K+ + ++LE+KHSQ+TE +NL+Q
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 199 -----EKEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQISHLQFVIHS 252
E+ + L +K LE L ++++ + Q LQ E + +Q+ L+ +
Sbjct: 902 LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 961
Query: 253 QHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
+ + + E + +K+ + I + ++ N L + K L+ +++ + + K
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Query: 313 AVSTSELKTEGVSPYLML-IRLRK 335
A + ++LK + S L +RL+K
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKK 1045
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/202 (20%), Positives = 89/202 (44%), Gaps = 14/202 (6%)
Query: 104 EMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEV-----RKKQEDSKQLLQV 158
E K+ + L+ L +E AAA R Q E + E R +D K+ L+
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 1736
Query: 159 NKLEKEQKLKQHVENLNQVAEKLEEKHSQITELEN--LVQRMEKEKRTLLERKLSLENKL 216
+ E++L++ N+ +++++ + Q +L N +R +K ++L +NK
Sbjct: 1737 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Query: 217 LQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDK 276
L+ K G + I+ L+ +I+ L+ + + +E + +LK++DK
Sbjct: 1797 LRSKLHEMEGAVKSKFKSTIAALEAKIAQLE-------EQVEQEAREKQAATKSLKQKDK 1849
Query: 277 RIENLREKVNILEAQNKELKTQ 298
+++ + +V ++ K Q
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQ 1871
Score = 45.8 bits (107), Expect = 5e-05
Identities = 67/342 (19%), Positives = 144/342 (42%), Gaps = 33/342 (9%)
Query: 6 VTTEIPPRDKMEDNSALYESTSAHIIEETEY----VKKIRTTLQKIRTQMFKD------- 54
+TT + ++ N ++ +I E E +K R L+K++ ++ D
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 55 --EIRHDSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKE---- 108
+++ K+ Q + + +D + +KKI+ + + ++ ++
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 109 ----NEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKE 164
N+ K K E AL+ + ++ TQ +E+R K+E +L+ E+
Sbjct: 1131 RAARNKAEKQKRDLGEEL--EALKTELEDTLDSTATQ-QELRAKREQEVTVLKKALDEET 1187
Query: 165 QKLKQHVENLNQV-AEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLL---QLK 220
+ + V+ + Q A+ +EE Q+ + + ++K K+TL + L +L Q K
Sbjct: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1247
Query: 221 SSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN 280
+ K + L+ ++ LQ + S + + + + E+E + L E + +
Sbjct: 1248 QEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 281 LREKVNILEAQNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
L + V L +Q ++ TQ L ET R K++ + +L+ E
Sbjct: 1306 LAKDVASLSSQLQD--TQELLQEET-RQKLNVSTKLRQLEEE 1344
Score = 37.7 bits (86), Expect = 0.015
Identities = 49/215 (22%), Positives = 98/215 (45%), Gaps = 32/215 (14%)
Query: 91 LMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR---NVAQRLFENYQTQSEEVRK 147
++ + +GK ++L K+ L +LQ ++E R NV+ +L Q EE R
Sbjct: 1295 MLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQKLNVSTKL-----RQLEEERN 1346
Query: 148 KQEDSKQLLQVNKLEKEQKLKQHVENLN----QVAEKLEEKHSQITELENLVQRMEKEKR 203
+D ++E +Q L++H+ LN +KL++ S + LE +R +KE
Sbjct: 1347 SLQDQLD----EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIE 1402
Query: 204 TLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQE 263
L ++ E K +A Y K L++ + LQ+++ L + +Q Q + ++ ++
Sbjct: 1403 NLTQQ---YEEK------AAAYDK----LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 264 MEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQ 298
L E+ ++ + EA+ +E +T+
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 58.9 bits (141), Expect = 6e-09
Identities = 66/320 (20%), Positives = 147/320 (45%), Gaps = 24/320 (7%)
Query: 15 KMEDN--SALYESTSAH--IIEETEYVKKIRTTLQKIRTQMFKDE-----IRHDSTNHKL 65
KME+ SA +E+ +IE T ++++ + + + ++ K E ++ D N +
Sbjct: 959 KMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAM 1018
Query: 66 DAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAA 125
+ + +E++ ++ L K + +L E ++ EVL+ +LQ + +
Sbjct: 1019 HLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKS 1078
Query: 126 ALRNVAQR--LFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK--- 180
LR + + + + Q EE +D L+ K+E E K ++ +E + E+
Sbjct: 1079 TLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWE 1138
Query: 181 LEEKHSQITELENLVQRMEKE-KRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISIL 239
L+++ +Q+T L+ ++ E ++ +++ + +LE L+LK K + L ++
Sbjct: 1139 LKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKEC---NKQIESLNDKLQNA 1195
Query: 240 QEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
+EQ+ +F++ Q + + +E+E + +KE + ++E+ + Q KE +
Sbjct: 1196 KEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEME---SVMKEQEQYIATQYKE---AI 1249
Query: 300 ALSSETPRTKVSKAVSTSEL 319
L E T+ S +EL
Sbjct: 1250 DLGQELRLTREQVQNSHTEL 1269
Score = 48.1 bits (113), Expect = 1e-05
Identities = 58/241 (24%), Positives = 112/241 (46%), Gaps = 44/241 (18%)
Query: 90 LLMKKIKGKDLQLLEMNKENEVLKIK--LQASREAGAAALRNVAQRLFENYQTQSEEVRK 147
L + I+ +L+ + E +V K++ LQ RE+ A LR + ++ E+ +++ R+
Sbjct: 918 LQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKC-ESAAHEADLKRQ 976
Query: 148 KQ------------EDSKQLLQVNKLEKE-QKLKQHVEN-----------LNQVAEKLEE 183
K E + +++K+EKE LK+ EN L+Q +LE+
Sbjct: 977 KVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEK 1036
Query: 184 KHSQITELENLVQRMEKEKRTLLERKLSLENKLL----QLKSSATYGKSCQDLQREISIL 239
K + + ELE L E E L+++ LE +L +LKS+ R++ L
Sbjct: 1037 KTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTL----------RQLQEL 1086
Query: 240 QEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
++ + Q + ++ ++ + E+ K ++ +DK+ + L E L+ +N ELK +
Sbjct: 1087 RDVLQKAQLSLEEKYTTIKDLTAELRECK--MEIEDKK-QELLEMDQALKERNWELKQRA 1143
Query: 300 A 300
A
Sbjct: 1144 A 1144
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/209 (20%), Positives = 98/209 (46%), Gaps = 41/209 (19%)
Query: 99 DLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQV 158
D+ + E E E IKL+ + E L+ +++ E + K +++K+ L+
Sbjct: 1150 DMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQI--------ESLNDKLQNAKEQLR- 1200
Query: 159 NKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQ 218
EKE + Q+ + ++Q+ +++E ++ E+E++++ E
Sbjct: 1201 ---EKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQE------------------- 1238
Query: 219 LKSSATYGKSCQDLQREISILQEQI--SHLQFVIHSQHQNLRS------VIQEMEGLKNN 270
+ AT K DL +E+ + +EQ+ SH + + ++HQ +++ + E+E +K
Sbjct: 1239 -QYIATQYKEAIDLGQELRLTREQVQNSHTE-LAEARHQQVQAQREIERLSSELEDMKQL 1296
Query: 271 LKEQDKRIENLREKVNILEAQNKELKTQV 299
KE+D +L E++ + + L+ ++
Sbjct: 1297 SKEKDAHGNHLAEELGASKVREAHLEARM 1325
Score = 44.3 bits (103), Expect = 2e-04
Identities = 46/212 (21%), Positives = 92/212 (43%), Gaps = 15/212 (7%)
Query: 113 KIKLQASREAGAAALRNVAQRLF--ENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQH 170
K+ + S + AA++ + +++ E + ++V ++ E+ + Q +EKEQ L++
Sbjct: 272 KVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQES 331
Query: 171 VENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQ 230
E ++ L E+ Q +R E+++ L L Q K + +
Sbjct: 332 KEECIKLKVDLLEQTKQ-------GKRAERQRNEALYNAEELSKAFQQYKKKVA--EKLE 382
Query: 231 DLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEA 290
+Q E IL+ +++ + + E+E LK L++ + N +EK+ I+
Sbjct: 383 KVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAV 442
Query: 291 QNKELKTQVALSSETPRTKVSKAVSTSELKTE 322
+N E+ Q+ S R + K S E K E
Sbjct: 443 KNSEVMAQLTES----RQSILKLESELENKDE 470
Score = 43.5 bits (101), Expect = 3e-04
Identities = 60/311 (19%), Positives = 138/311 (44%), Gaps = 34/311 (10%)
Query: 38 KKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGN---------LQQGS-----DSEMDP 83
+++ T ++++RT++ +I ++++ K++ H + L++ S +SEM
Sbjct: 637 QRLVTGIEELRTKLI--QIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTK 694
Query: 84 SCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQR------LFEN 137
C L L K+++ K + + +N L+ +L E + N+ FE
Sbjct: 695 KCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEK 754
Query: 138 YQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQ- 196
+ E K+ E + L+ +K+Q+ K+ + ++ + + + K + L+ L+
Sbjct: 755 AKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTE 814
Query: 197 ---RMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQ 253
M+KE E +L+N++ + S ++ +E +L ++ L+
Sbjct: 815 SKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVL--HLNQLEGNKEKF 872
Query: 254 HQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILE---AQNKELKTQVALSS---ETPR 307
+ L+ +E+ L+ LK ++ ++ E+ IL+ Q +++ Q + + E +
Sbjct: 873 EKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQ 932
Query: 308 TKVSKAVSTSE 318
TK+ K VS E
Sbjct: 933 TKLEKQVSKLE 943
Score = 40.8 bits (94), Expect = 0.002
Identities = 71/377 (18%), Positives = 153/377 (40%), Gaps = 77/377 (20%)
Query: 13 RDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKH--- 69
R + + N ALY + + +Y KK+ L+K++ + ++ + + TN + + K
Sbjct: 351 RAERQRNEALYNAEELSKAFQ-QYKKKVAEKLEKVQAE--EEILERNLTNCEKENKRLQE 407
Query: 70 -CGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR 128
CG + L++L +K++ QL E N + K+++ A + + A
Sbjct: 408 RCGLYKS-----------ELEILKEKLR----QLKEENNNGKE-KLRIMAVKNSEVMAQL 451
Query: 129 NVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQI 188
+++ +++ E + D L+ N+ K + Q+ E L+ +++E ++
Sbjct: 452 TESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQN-ERLDLCQQEIESSRVEL 510
Query: 189 TELENLVQRM--------------------------------EKEKRTLLERKLSL---E 213
LE ++ ++ E K + E ++ L E
Sbjct: 511 RSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKE 570
Query: 214 NKLLQLKSSATYGK------SCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGL 267
++ +L ++ T + +C D Q + + ++ HQ SV + +
Sbjct: 571 AEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKL---GGHQVAESVKDQNQHT 627
Query: 268 KNNLKEQDKR-----IENLREKVNILEAQNKELKTQVALSSE----TPRTKVSKAVSTSE 318
N E++++ IE LR K+ +EA+N +LK +A + + KA ++S+
Sbjct: 628 MNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSK 687
Query: 319 LKTEGVSPYLMLIRLRK 335
L++E L+ L K
Sbjct: 688 LESEMTKKCSQLLTLEK 704
Score = 32.0 bits (71), Expect = 0.80
Identities = 30/138 (21%), Positives = 63/138 (45%), Gaps = 11/138 (7%)
Query: 172 ENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLEN---KLLQLKSSATYGKS 228
++L ++ + +++ E E+L+ + + L + SL++ +L + S +
Sbjct: 114 DDLGEMESSSSDYYNKDNEEESLLANVASLRHELKITEWSLQSLGEELSSVSPSENSDYA 173
Query: 229 CQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQ--------DKRIEN 280
+ E IL Q SH + +S ++N+ + + +++ D+ I++
Sbjct: 174 PNPSRSEKLILDVQPSHPGLLNYSPYENVCKISGSSTDFQKKPRDKMFSSSAPVDQEIKS 233
Query: 281 LREKVNILEAQNKELKTQ 298
LREK+N L QN L TQ
Sbjct: 234 LREKLNKLRQQNACLVTQ 251
>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
sapiens]
Length = 513
Score = 58.9 bits (141), Expect = 6e-09
Identities = 61/227 (26%), Positives = 106/227 (46%), Gaps = 34/227 (14%)
Query: 87 SLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVR 146
S + +++K+ + + +N EN LK L A ++ + EN ++ +EV
Sbjct: 195 SCEEILRKVHSIEYENETLNLENTKLKTTLAALKDEVVSV---------ENELSELQEVE 245
Query: 147 KKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENL-VQRME------ 199
KKQ K L+++ K + QKL++ E + E L K++QIT+ +N V++M
Sbjct: 246 KKQ---KTLIEMYKTQV-QKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMESH 301
Query: 200 -KEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQISHLQFVIHSQHQNL 257
KE + + + E +L + + S K C D + I LQ Q+ H L
Sbjct: 302 LKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQVD-------GNHNLL 354
Query: 258 RSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSE 304
+ E E LK ENL++K+ ++A+NKEL+ ++A E
Sbjct: 355 TKLSLEEENCLIQLK-----CENLQQKLEQMDAENKELEKKLANQEE 396
Score = 41.6 bits (96), Expect = 0.001
Identities = 60/312 (19%), Positives = 129/312 (41%), Gaps = 50/312 (16%)
Query: 16 MEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQ 75
+++ S L++S A+ ++ + + ++ ++++ Q+ K E +D + +
Sbjct: 27 IQELSCLFQSEKANTLKANRFSQSVKVVHERLQIQIHKREAENDKLKEYVKS-------- 78
Query: 76 GSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR--NVAQR 133
L KI +LQ MNK NE + +K +ASR+ A + V ++
Sbjct: 79 ---------------LETKIAKWNLQS-RMNK-NEAIVMK-EASRQKTVALKKASKVYKQ 120
Query: 134 LFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELEN 193
+++ E++ + D + L + K H E + V EK TELE
Sbjct: 121 RLDHFTGAIEKLTSQIRDQEAKLS-ETISASNAWKSHYEKI--VIEK--------TELEV 169
Query: 194 LVQRMEKEKRTLLERKLSLENKLLQLKSSATYGK-SCQDLQREISILQEQISHLQFVIHS 252
++ M+K+ LLE LK +GK SC+++ R++ ++ + L
Sbjct: 170 QIETMKKQIINLLE----------DLKKMEDHGKNSCEEILRKVHSIEYENETLNLENTK 219
Query: 253 QHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
L ++ E+ ++N L E + + + + + + Q ++L+ + + K
Sbjct: 220 LKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHK 279
Query: 313 AVSTSELKTEGV 324
++ K + V
Sbjct: 280 NNQITKTKNKNV 291
Score = 39.3 bits (90), Expect = 0.005
Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 23/179 (12%)
Query: 59 DSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDL----LMKKIKGKDLQLLEMNK----ENE 110
+ T +L + GN + ++ C + L L +K++ D + E+ K + E
Sbjct: 337 EHTIRELQGQVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKELEKKLANQEE 396
Query: 111 VLK---IKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKL 167
LK +K + A R + L E Q +EE+ +K + LQ+ L+ E +L
Sbjct: 397 CLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEI-EKMSSRESALQIKILDLETEL 455
Query: 168 KQHVENLNQVAEKLEEK--HSQI--TELENLVQRMEKEKRTLLERKLSLENKLLQLKSS 222
++ E NQ+ K+ K H ++ E++N +++ E + S++N L LK+S
Sbjct: 456 RKKNEEQNQLVCKMNSKAQHQEVCLKEVQNSLEKSENQNE-------SIKNYLQFLKTS 507
>gi|55749696 outer dense fiber of sperm tails 2-like isoform a [Homo
sapiens]
Length = 644
Score = 58.9 bits (141), Expect = 6e-09
Identities = 61/227 (26%), Positives = 106/227 (46%), Gaps = 34/227 (14%)
Query: 87 SLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVR 146
S + +++K+ + + +N EN LK L A ++ + EN ++ +EV
Sbjct: 326 SCEEILRKVHSIEYENETLNLENTKLKTTLAALKDEVVSV---------ENELSELQEVE 376
Query: 147 KKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENL-VQRME------ 199
KKQ K L+++ K + QKL++ E + E L K++QIT+ +N V++M
Sbjct: 377 KKQ---KTLIEMYKTQV-QKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMESH 432
Query: 200 -KEKRTLLERKLSLENKLLQLKSSATYGKS-CQDLQREISILQEQISHLQFVIHSQHQNL 257
KE + + + E +L + + S K C D + I LQ Q+ H L
Sbjct: 433 LKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQVD-------GNHNLL 485
Query: 258 RSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSE 304
+ E E LK ENL++K+ ++A+NKEL+ ++A E
Sbjct: 486 TKLSLEEENCLIQLK-----CENLQQKLEQMDAENKELEKKLANQEE 527
Score = 41.6 bits (96), Expect = 0.001
Identities = 60/312 (19%), Positives = 129/312 (41%), Gaps = 50/312 (16%)
Query: 16 MEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQ 75
+++ S L++S A+ ++ + + ++ ++++ Q+ K E +D + +
Sbjct: 158 IQELSCLFQSEKANTLKANRFSQSVKVVHERLQIQIHKREAENDKLKEYVKS-------- 209
Query: 76 GSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALR--NVAQR 133
L KI +LQ MNK NE + +K +ASR+ A + V ++
Sbjct: 210 ---------------LETKIAKWNLQS-RMNK-NEAIVMK-EASRQKTVALKKASKVYKQ 251
Query: 134 LFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELEN 193
+++ E++ + D + L + K H E + V EK TELE
Sbjct: 252 RLDHFTGAIEKLTSQIRDQEAKLS-ETISASNAWKSHYEKI--VIEK--------TELEV 300
Query: 194 LVQRMEKEKRTLLERKLSLENKLLQLKSSATYGK-SCQDLQREISILQEQISHLQFVIHS 252
++ M+K+ LLE LK +GK SC+++ R++ ++ + L
Sbjct: 301 QIETMKKQIINLLE----------DLKKMEDHGKNSCEEILRKVHSIEYENETLNLENTK 350
Query: 253 QHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSK 312
L ++ E+ ++N L E + + + + + + Q ++L+ + + K
Sbjct: 351 LKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHK 410
Query: 313 AVSTSELKTEGV 324
++ K + V
Sbjct: 411 NNQITKTKNKNV 422
Score = 39.3 bits (90), Expect = 0.005
Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 23/179 (12%)
Query: 59 DSTNHKLDAKHCGNLQQGSDSEMDPSCCSLDL----LMKKIKGKDLQLLEMNK----ENE 110
+ T +L + GN + ++ C + L L +K++ D + E+ K + E
Sbjct: 468 EHTIRELQGQVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKELEKKLANQEE 527
Query: 111 VLK---IKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKL 167
LK +K + A R + L E Q +EE+ +K + LQ+ L+ E +L
Sbjct: 528 CLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEI-EKMSSRESALQIKILDLETEL 586
Query: 168 KQHVENLNQVAEKLEEK--HSQI--TELENLVQRMEKEKRTLLERKLSLENKLLQLKSS 222
++ E NQ+ K+ K H ++ E++N +++ E + S++N L LK+S
Sbjct: 587 RKKNEEQNQLVCKMNSKAQHQEVCLKEVQNSLEKSENQNE-------SIKNYLQFLKTS 638
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 58.5 bits (140), Expect = 8e-09
Identities = 70/324 (21%), Positives = 151/324 (46%), Gaps = 31/324 (9%)
Query: 17 EDNSALYESTSAHIIEETEY-VKKIRTTLQK--IRTQMFKDEIRHDSTNHKLDAKHCGNL 73
++N + S I+E EY ++++R LQ+ R + +++E+ ++ + NL
Sbjct: 1150 KENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYN---EEMSNL 1206
Query: 74 QQGSDSEMDPSCCSLD--LLMKKIKGKDL--QLLEMNKENEVLK---IKLQASREAGAAA 126
+ ++E++ + ++ + K+ K+L QL +++EN LK ++L S
Sbjct: 1207 RNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQ 1266
Query: 127 LRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHS 186
R + + SE ++KKQ +L QV + E + H ++L + A+ +++K+
Sbjct: 1267 RRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNAR-HKQSLEEAAKTIQDKNK 1325
Query: 187 QITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDL----QREISILQEQ 242
+I +R++ E + +R+ EN+L +++++ Y + L + EI+I +
Sbjct: 1326 EI-------ERLKAEFQEEAKRRWEYENELSKVRNN--YDEEIISLKNQFETEINITKTT 1376
Query: 243 ISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN-LREKVNILEAQNKELKTQVAL 301
I L R+ I + +L E+ KR++N L + L ++++ Q A
Sbjct: 1377 IHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKAT 1436
Query: 302 SSETPRTKVSKAV---STSELKTE 322
SE + K V ++++TE
Sbjct: 1437 GSEVSQRKQQLEVELRQVTQMRTE 1460
Score = 53.5 bits (127), Expect = 3e-07
Identities = 58/322 (18%), Positives = 145/322 (45%), Gaps = 51/322 (15%)
Query: 13 RDKMEDNSA---LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKH 69
+ + EDN+ E + I ++ + +++++ Q+ + ++ E + D +
Sbjct: 1300 QQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEI 1359
Query: 70 CGNLQQGSDSEMDPSCCSL-DLLMKK---IKGKDLQLLEMNKENEVLKIKLQASREAGAA 125
+L+ ++E++ + ++ L M+K G Q+ + +EN L +++ +
Sbjct: 1360 I-SLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQ 1418
Query: 126 A---LRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLE 182
LR V + + + T SE ++KQ+ +L QV ++ E+ ++ + ++L+ A+ ++
Sbjct: 1419 TTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVR-YKQSLDDAAKTIQ 1477
Query: 183 EKHSQITELENLVQRMEKEKRTLLERKLSLEN---KLLQLKSSAT--------------- 224
+K+ +I L+ L+ + +++ L + L+ L + SSAT
Sbjct: 1478 DKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTR 1537
Query: 225 ---------------------YGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQE 263
+ S ++LQ + ++E+++ L+ + + +E
Sbjct: 1538 LRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEE 1597
Query: 264 MEGLKNNLKEQDKRIENLREKV 285
+EG++ +LKEQ +I NL +++
Sbjct: 1598 LEGMRRSLKEQAIKITNLTQQL 1619
Score = 48.5 bits (114), Expect = 8e-06
Identities = 54/280 (19%), Positives = 121/280 (43%), Gaps = 26/280 (9%)
Query: 23 YESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEMD 82
YE S + + + + + +L++++ Q K ++ + K A ++ + E++
Sbjct: 1542 YERVSQERTVKDQDITRFQNSLKELQLQ--KQKVEEELNRLKRTASEDSCKRKKLEEELE 1599
Query: 83 PSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQS 142
+ + +K + +++ + ++ E I + S E R+V Q
Sbjct: 1600 G-------MRRSLKEQAIKITNLTQQLEQASIVKKRS-EDDLRQQRDVLDGHLREKQRTQ 1651
Query: 143 EEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEK 202
EE+R+ + + L + E+E + H+ N + +E+K + E + ++R++
Sbjct: 1652 EELRRLSSEVEALRRQLLQEQESVKQAHLRN-EHFQKAIEDKSRSLNESKIEIERLQSLT 1710
Query: 203 RTLLERKLSLENKLLQLK---SSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRS 259
L + L LE +L L+ G+S D + +IL+ + SQ Q +
Sbjct: 1711 ENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILE---------LRSQLQISNN 1761
Query: 260 VIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQV 299
E++GL N+L+ + ENLR+++ + Q E ++
Sbjct: 1762 RTLELQGLINDLQRER---ENLRQEIEKFQKQALEASNRI 1798
Score = 38.9 bits (89), Expect = 0.007
Identities = 37/198 (18%), Positives = 86/198 (43%), Gaps = 29/198 (14%)
Query: 101 QLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNK 160
Q+ E+N++ L +++ + R + F+ + ++++K ++ K+ L K
Sbjct: 1103 QIKELNEKITRLTYEIEDEKRR-----RKSVEDRFDQQKNDYDQLQKARQCEKENLGWQK 1157
Query: 161 LEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLK 220
LE E+ +K+ + ++ L+E+ ++ E EN + K + E +L NK
Sbjct: 1158 LESEKAIKEKEYEIERLRVLLQEEGTRKREYEN---ELAKVRNHYNEEMSNLRNK----- 1209
Query: 221 SSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIEN 280
+ EI+I + I + +NLR+ + + +LK++ R+ +
Sbjct: 1210 -----------YETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLND 1258
Query: 281 LREKVNILEAQNKELKTQ 298
+IL+A + + +
Sbjct: 1259 -----SILQATEQRRRAE 1271
Score = 38.5 bits (88), Expect = 0.009
Identities = 57/245 (23%), Positives = 116/245 (47%), Gaps = 15/245 (6%)
Query: 87 SLDLLMKKIKGKDLQLLEMN--KENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEE 144
S L KI+ + LQ L N KE+ +L+ +L+ R R ++ + T E
Sbjct: 1693 SRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILEL 1752
Query: 145 VRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRT 204
+ Q + + L++ L + L++ ENL Q EK ++ Q E N +Q + +
Sbjct: 1753 RSQLQISNNRTLELQGLIND--LQRERENLRQEIEKFQK---QALEASNRIQESKNQCTQ 1807
Query: 205 LLERKLSLENKLLQLKSSATYGKSCQD-LQREISILQEQISHLQFVIHSQHQNLRSVIQE 263
+++ + SL K+ L+ + +D L R S L+ + + ++ + + Q +++ + +
Sbjct: 1808 VVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAE-TRVKQRLECEKQQIQNDLNQ 1866
Query: 264 MEGLKNNLKEQDKRIENLREK----VNILEAQNKELKTQVALSSETPRTKV--SKAVSTS 317
+ + +E ++IE+ REK N L ++ + L+ ++ E R K+ S + S
Sbjct: 1867 WKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQS 1926
Query: 318 ELKTE 322
+L+TE
Sbjct: 1927 QLETE 1931
Score = 31.2 bits (69), Expect = 1.4
Identities = 37/197 (18%), Positives = 93/197 (47%), Gaps = 19/197 (9%)
Query: 113 KIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQE----DSKQLLQVNKLEKEQKLK 168
KIK ++ L + L + + + +R+ Q S++++ +N E+E+ L
Sbjct: 237 KIKADLREKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLY 296
Query: 169 QHVENLNQVAEKLEE---KHSQITELENLVQRMEKEKRTLLERKLSLENKL-LQLKSSAT 224
+ +A+K E + SQ+ E + ++++E L+ + +K+ + + T
Sbjct: 297 DWSDKNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQT 356
Query: 225 YGKSCQDLQREISI-LQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQ---DKR--I 278
+ + I + L+E ++ QF +Q S ++GL+++++++ DK +
Sbjct: 357 QWSWILQITKCIDVHLKENAAYFQFFEEAQ-----STEAYLKGLQDSIRKKYPCDKNMPL 411
Query: 279 ENLREKVNILEAQNKEL 295
++L E++ LE + +++
Sbjct: 412 QHLLEQIKELEKEREKI 428
Score = 28.9 bits (63), Expect = 6.8
Identities = 35/163 (21%), Positives = 76/163 (46%), Gaps = 23/163 (14%)
Query: 132 QRLFENYQTQSEEVRKKQED-SKQLLQVNKLEKE-QKLKQHVENLNQVAEKLEEKHSQIT 189
+ L ++ ++ + +KQE S ++ Q+ EKE KLKQ + L + +H
Sbjct: 292 EELLYDWSDKNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESDQL------VLNQHPASD 345
Query: 190 ELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFV 249
++E + ++ + +L+ ++ + LK +A Y + ++ Q + L+ LQ
Sbjct: 346 KIEAYMDTLQTQWSWILQITKCID---VHLKENAAYFQFFEEAQSTEAYLKG----LQDS 398
Query: 250 IHSQH--------QNLRSVIQEMEGLKNNLKEQDKRIENLREK 284
I ++ Q+L I+E+E + + E ++++NL K
Sbjct: 399 IRKKYPCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNK 441
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.320
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,521,666
Number of Sequences: 37866
Number of extensions: 437955
Number of successful extensions: 9332
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 445
Number of HSP's successfully gapped in prelim test: 1016
Number of HSP's that attempted gapping in prelim test: 3679
Number of HSP's gapped (non-prelim): 3928
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.