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Search of human proteins with 5174633
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
(2253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 4549 0.0
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 233 2e-60
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 182 2e-45
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 182 2e-45
gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] 182 3e-45
gi|31559825 polycystin 1-like 3 [Homo sapiens] 182 3e-45
gi|19923084 polycystin-1L1 [Homo sapiens] 151 8e-36
gi|4505835 polycystin 2 [Homo sapiens] 129 3e-29
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 128 7e-29
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] 110 1e-23
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 103 2e-21
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 103 2e-21
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 70 3e-11
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 70 3e-11
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 65 6e-10
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 60 2e-08
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 57 2e-07
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 57 2e-07
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 57 2e-07
gi|10092597 mucolipin 1 [Homo sapiens] 56 5e-07
gi|24496763 mucolipin 3 [Homo sapiens] 54 2e-06
gi|237512982 voltage-gated sodium channel type V alpha isoform f... 48 1e-04
gi|37622907 voltage-gated sodium channel type V alpha isoform a ... 48 1e-04
gi|30089970 voltage-gated sodium channel type V alpha isoform b ... 48 1e-04
gi|150417969 voltage-gated sodium channel type V alpha isoform d... 48 1e-04
gi|150417967 voltage-gated sodium channel type V alpha isoform c... 48 1e-04
gi|239748090 PREDICTED: similar to sodium channel, voltage-gated... 48 1e-04
gi|54792073 mucolipin 2 [Homo sapiens] 45 8e-04
gi|237512980 voltage-gated sodium channel type V alpha isoform e... 43 0.004
gi|110835710 sodium channel, voltage-gated, type X, alpha [Homo ... 40 0.020
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 4549 bits (11799), Expect = 0.0
Identities = 2253/2253 (100%), Positives = 2253/2253 (100%)
Query: 1 MRPGPALLLLGVGLSLSVGRLPLPPVPRGAQAAVSGAPGGLLRGAPGLGVRGGRALLSLR 60
MRPGPALLLLGVGLSLSVGRLPLPPVPRGAQAAVSGAPGGLLRGAPGLGVRGGRALLSLR
Sbjct: 1 MRPGPALLLLGVGLSLSVGRLPLPPVPRGAQAAVSGAPGGLLRGAPGLGVRGGRALLSLR 60
Query: 61 PSAVRAGGAVLSGRGSLCFPHGGTGRRWYCLDLRVLLSAQRLPWPAAPALALVDLQLSAR 120
PSAVRAGGAVLSGRGSLCFPHGGTGRRWYCLDLRVLLSAQRLPWPAAPALALVDLQLSAR
Sbjct: 61 PSAVRAGGAVLSGRGSLCFPHGGTGRRWYCLDLRVLLSAQRLPWPAAPALALVDLQLSAR 120
Query: 121 GGRLSLTWSVRLPRSPGRLAWAFRLRLLGPGAARPASPAARVSPRSAAPGPRPQQGFVAR 180
GGRLSLTWSVRLPRSPGRLAWAFRLRLLGPGAARPASPAARVSPRSAAPGPRPQQGFVAR
Sbjct: 121 GGRLSLTWSVRLPRSPGRLAWAFRLRLLGPGAARPASPAARVSPRSAAPGPRPQQGFVAR 180
Query: 181 TECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRINTDQKGAPVRLSMQAEAT 240
TECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRINTDQKGAPVRLSMQAEAT
Sbjct: 181 TECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRINTDQKGAPVRLSMQAEAT 240
Query: 241 INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLPQLEIRNSPLFIHIPNNSLQW 300
INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLPQLEIRNSPLFIHIPNNSLQW
Sbjct: 241 INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLPQLEIRNSPLFIHIPNNSLQW 300
Query: 301 GVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVMLGDANITANFTEQLILDGST 360
GVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVMLGDANITANFTEQLILDGST
Sbjct: 301 GVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVMLGDANITANFTEQLILDGST 360
Query: 361 SSDPDADSPLQGLQFFWYCTTDPRNYGGDRIILGSKEVCHPEQANLKWPWASGPVLTLLP 420
SSDPDADSPLQGLQFFWYCTTDPRNYGGDRIILGSKEVCHPEQANLKWPWASGPVLTLLP
Sbjct: 361 SSDPDADSPLQGLQFFWYCTTDPRNYGGDRIILGSKEVCHPEQANLKWPWASGPVLTLLP 420
Query: 421 ETLKGDHVYFFRMVIRKDSRTAFSDKRVHVLQGPKAIAHITCIENCERNFIVSDRFSLFL 480
ETLKGDHVYFFRMVIRKDSRTAFSDKRVHVLQGPKAIAHITCIENCERNFIVSDRFSLFL
Sbjct: 421 ETLKGDHVYFFRMVIRKDSRTAFSDKRVHVLQGPKAIAHITCIENCERNFIVSDRFSLFL 480
Query: 481 NCTNCASRDFYKWSILSSSGGEMLFDWMGETVTGRNGAYLSIKAFAFRHFLEAEFSISLY 540
NCTNCASRDFYKWSILSSSGGEMLFDWMGETVTGRNGAYLSIKAFAFRHFLEAEFSISLY
Sbjct: 481 NCTNCASRDFYKWSILSSSGGEMLFDWMGETVTGRNGAYLSIKAFAFRHFLEAEFSISLY 540
Query: 541 LACWSGVTSVFRHSFIINHGPQIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIV 600
LACWSGVTSVFRHSFIINHGPQIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIV
Sbjct: 541 LACWSGVTSVFRHSFIINHGPQIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIV 600
Query: 601 SDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQ 660
SDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQ
Sbjct: 601 SDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQ 660
Query: 661 VTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNM 720
VTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNM
Sbjct: 661 VTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNM 720
Query: 721 KTELPLRDDRVNLRKHLIDQSFLLPVSTLVEIGQVVMTITKLTQKPSEFTWDAQKRATMR 780
KTELPLRDDRVNLRKHLIDQSFLLPVSTLVEIGQVVMTITKLTQKPSEFTWDAQKRATMR
Sbjct: 721 KTELPLRDDRVNLRKHLIDQSFLLPVSTLVEIGQVVMTITKLTQKPSEFTWDAQKRATMR 780
Query: 781 VWQANQALQEYQQKDKRFRSEQIEIVSTGILMSLSNILKMTSPHQVVKDPFYVIESLSDT 840
VWQANQALQEYQQKDKRFRSEQIEIVSTGILMSLSNILKMTSPHQVVKDPFYVIESLSDT
Sbjct: 781 VWQANQALQEYQQKDKRFRSEQIEIVSTGILMSLSNILKMTSPHQVVKDPFYVIESLSDT 840
Query: 841 ILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFRNEKHCRNCFYPTLNVSSVPGLSAN 900
ILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFRNEKHCRNCFYPTLNVSSVPGLSAN
Sbjct: 841 ILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFRNEKHCRNCFYPTLNVSSVPGLSAN 900
Query: 901 GPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMTGVADNGSVLEITPDVAEVYLVRKNLT 960
GPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMTGVADNGSVLEITPDVAEVYLVRKNLT
Sbjct: 901 GPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMTGVADNGSVLEITPDVAEVYLVRKNLT 960
Query: 961 FAAFNLTVGPNSEVDGSLKKTTGGFSFQVDSTVLREVLVHIVTEVMVLFTVLVYTGSQIT 1020
FAAFNLTVGPNSEVDGSLKKTTGGFSFQVDSTVLREVLVHIVTEVMVLFTVLVYTGSQIT
Sbjct: 961 FAAFNLTVGPNSEVDGSLKKTTGGFSFQVDSTVLREVLVHIVTEVMVLFTVLVYTGSQIT 1020
Query: 1021 PTALVATFLVPHDIPPFASQSALFDPACTVKKARVVCLPVSLLQLIAQHSHSPHCTVSIV 1080
PTALVATFLVPHDIPPFASQSALFDPACTVKKARVVCLPVSLLQLIAQHSHSPHCTVSIV
Sbjct: 1021 PTALVATFLVPHDIPPFASQSALFDPACTVKKARVVCLPVSLLQLIAQHSHSPHCTVSIV 1080
Query: 1081 LQAPRFVMKLNDKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRA 1140
LQAPRFVMKLNDKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRA
Sbjct: 1081 LQAPRFVMKLNDKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRA 1140
Query: 1141 RRQLGTIGLTGIHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGL 1200
RRQLGTIGLTGIHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGL
Sbjct: 1141 RRQLGTIGLTGIHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGL 1200
Query: 1201 AFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVST 1260
AFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVST
Sbjct: 1201 AFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVST 1260
Query: 1261 SDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLF 1320
SDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLF
Sbjct: 1261 SDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLF 1320
Query: 1321 SRHIWLFICQKWLSVDTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVV 1380
SRHIWLFICQKWLSVDTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVV
Sbjct: 1321 SRHIWLFICQKWLSVDTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVV 1380
Query: 1381 AKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMRSMMIGIESVLITIPV 1440
AKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMRSMMIGIESVLITIPV
Sbjct: 1381 AKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMRSMMIGIESVLITIPV 1440
Query: 1441 QLLITFLFTCSQRKPQADLKEVSPQKHPLMSEASEHWEEYLRKWHAYETAKVHPREVAKP 1500
QLLITFLFTCSQRKPQADLKEVSPQKHPLMSEASEHWEEYLRKWHAYETAKVHPREVAKP
Sbjct: 1441 QLLITFLFTCSQRKPQADLKEVSPQKHPLMSEASEHWEEYLRKWHAYETAKVHPREVAKP 1500
Query: 1501 ASKGKPRLPKASPKATSKPKHRHRKAQIKTPETLGPNTNSNNNIEDDQDVHSEQHPSQKD 1560
ASKGKPRLPKASPKATSKPKHRHRKAQIKTPETLGPNTNSNNNIEDDQDVHSEQHPSQKD
Sbjct: 1501 ASKGKPRLPKASPKATSKPKHRHRKAQIKTPETLGPNTNSNNNIEDDQDVHSEQHPSQKD 1560
Query: 1561 LQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQ 1620
LQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQ
Sbjct: 1561 LQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQ 1620
Query: 1621 SVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQIVRI 1680
SVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQIVRI
Sbjct: 1621 SVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQIVRI 1680
Query: 1681 RGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN 1740
RGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN
Sbjct: 1681 RGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN 1740
Query: 1741 QFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMRQVRAK 1800
QFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMRQVRAK
Sbjct: 1741 QFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMRQVRAK 1800
Query: 1801 SSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKP 1860
SSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKP
Sbjct: 1801 SSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKP 1860
Query: 1861 QGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTT 1920
QGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTT
Sbjct: 1861 QGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTT 1920
Query: 1921 FNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAYVV 1980
FNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAYVV
Sbjct: 1921 FNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAYVV 1980
Query: 1981 DEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPF 2040
DEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPF
Sbjct: 1981 DEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPF 2040
Query: 2041 HAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYF 2100
HAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYF
Sbjct: 2041 HAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYF 2100
Query: 2101 FVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNRILGVLFLSSFMLVMI 2160
FVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNRILGVLFLSSFMLVMI
Sbjct: 2101 FVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNRILGVLFLSSFMLVMI 2160
Query: 2161 CVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKAKDEPEFF 2220
CVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKAKDEPEFF
Sbjct: 2161 CVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKAKDEPEFF 2220
Query: 2221 IDMLYGQPEKNSHRYLGLKTRNINGKKMVYLVV 2253
IDMLYGQPEKNSHRYLGLKTRNINGKKMVYLVV
Sbjct: 2221 IDMLYGQPEKNSHRYLGLKTRNINGKKMVYLVV 2253
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 233 bits (593), Expect = 2e-60
Identities = 179/664 (26%), Positives = 306/664 (46%), Gaps = 33/664 (4%)
Query: 1556 PSQKDLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASF 1615
P+ Q+ K P+ LPWWC+ V W LV ATS +++FF + YGL YG S+ WL +
Sbjct: 1802 PAHASALQVSKPPQ-GLPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMA 1860
Query: 1616 CSFCQSVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHD 1675
SF +S+ + QP K++ + F + L + T L G + P+
Sbjct: 1861 VSFVESMFVTQPLKVLGFAAF------FALVLKRVDDEEDTVAPLPGHLLGPDPYALFRA 1914
Query: 1676 QIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTD 1735
+ R +YQP I K +++A + IL + FL +LL++ R
Sbjct: 1915 R--RNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPS 1972
Query: 1736 CFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMR 1795
++ N+ ++ F+ + V + ++W N+ L+ L+ P F+ + +SK++G +R
Sbjct: 1973 AYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYGH-PPGFITDGNSKLVGSAQIR 2031
Query: 1796 QVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNG 1855
QVR + S + N C Y +D ED +Y WN + +
Sbjct: 2032 QVRVQESSCPLAQQPQAYLNG------CRAPYSLDAEDMADYGEGWNAT-------TLSE 2078
Query: 1856 FTYKPQGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVV 1915
+ Y+ Q + Y +G L Y GGY + ++Q + LR L ++ WLD T AV
Sbjct: 2079 WQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQSTSRILRY--LFDNTWLDALTRAVF 2136
Query: 1916 LELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADF-DRKASAEIYLYVAILIF 1974
+E T +N ++NLFC +++ E S LG T +L S L F D + + +F
Sbjct: 2137 VESTVYNANVNLFCIVTLTLETSALGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLF 2196
Query: 1975 FLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNP 2034
L Y+V +G + +E Y S +NLL A+ + +F+++ LA ++ ++
Sbjct: 2197 LLYYMVVQGKRMSKETWGYFCSKWNLLELAIILASWSALAVFVKRAVLAERDLQRCRNHR 2256
Query: 2035 EDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAF 2094
E+ I F + D + I+ FL+ L+ +K R + + A++ A I
Sbjct: 2257 EEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMI 2316
Query: 2095 VVSVYFFVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTE-FSNNRILGVLFLS 2153
V+ Y L+FG +Y L + +T+ S + F E + +LG +
Sbjct: 2317 VILTMLLAYSIASNLIFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIG 2376
Query: 2154 SFMLVMICVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKA 2213
S ++ M V++NLF +VIL A+ E ++ Y + S+E E + L K+ SFL +SK
Sbjct: 2377 SCIVFMTFVVLNLFISVILVAFSEEQK--YYQLSEEGEIVDLLLMKI---LSFLGIKSK- 2430
Query: 2214 KDEP 2217
++EP
Sbjct: 2431 REEP 2434
Score = 218 bits (555), Expect = 5e-56
Identities = 122/364 (33%), Positives = 191/364 (52%), Gaps = 25/364 (6%)
Query: 1092 DKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTG 1151
D V I+ F C+ +Q W + C +G +TS Y+ HC+C ++
Sbjct: 1270 DLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLT------------- 1316
Query: 1152 IHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211
T VM+ I I +L + NPV + TV + ++YV + WA +D D
Sbjct: 1317 FFGSTFLVMSNAINIHQTAEL----FATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQD 1372
Query: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271
Q + V VL DNDP+ YLVT++TG R G+ T + V V L G + H L+ P
Sbjct: 1373 Q-AKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431
Query: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
RG+++ FLL+T LG++ S+R+WH+N G PSWY+SR+ V +L W F+C
Sbjct: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491
Query: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388
WLS+ D LD+ F V +R FF+ S+ + H+W+SIF+ +F R+Q
Sbjct: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551
Query: 1389 RLSCCLAMLLSSLLCNIMFFNLNR----QEQTESRERKYMRSMMIGIESVLITIPVQLLI 1444
R+SCC ++LL ++L +IMF+ + + Q+ + + +MIG+ES ++ P+ LLI
Sbjct: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611
Query: 1445 TFLF 1448
+F
Sbjct: 1612 VQIF 1615
Score = 52.0 bits (123), Expect = 7e-06
Identities = 88/419 (21%), Positives = 165/419 (39%), Gaps = 61/419 (14%)
Query: 548 TSVFRHSF-----IINHGP--QIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIV 600
T++ RH++ +I+ P ++ C I P +G L T F + C N PL + +
Sbjct: 753 TALTRHAYGEDTYVISTVPPREVPACTIAPEEGTVL-TSFAIFC-NASTALGPLEFCFCL 810
Query: 601 SDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQ 660
G+ L+ GP+ +P +LP+G + + L + + G Q
Sbjct: 811 ES---------------GSCLHCGPEPALPSVYLPLGEENNDFVLTVVISATNRAGDTQQ 855
Query: 661 VTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNM 720
QA T + + +F S + T +Q + LL + +V + +
Sbjct: 856 T------QAMAKVALGDTCVEDV-AFQAAVSEKIPTALQGEG--GPEQLLQLAKAVSSML 906
Query: 721 KTELPLR--------DDRVNLRKHLIDQSFLLPVSTLVE----IGQVVMTITKLTQKPSE 768
E + D R +R+H++ L V+T +E + ++ + ++T + E
Sbjct: 907 NQEHESQGSGQSLSIDVRQKVREHVLGS--LSAVTTGLEDVQRVQELAEVLREVTCRSKE 964
Query: 769 FTWDAQKRATMRVWQANQALQEYQQK----DKRFRS---EQIEIVSTGILMSLSNILK-- 819
T AQ A++ + A++AL K D+R ++ + + V + + SLSN +
Sbjct: 965 LTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLEASLSNRPEEP 1024
Query: 820 ---MTSPHQVVKDPFYVIESLSDTILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFR 876
+S V V+E + T+L K+PG + TP+ ++Y +++ W
Sbjct: 1025 AEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQGSSL 1084
Query: 877 NEKHCRNCFYPTLNVSSVPGL-SANGPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMT 934
+ + SS+ L P+ F FP + S V G R+T
Sbjct: 1085 RPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFP-ARSHFDVSGTVGGLRVT 1142
>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1732
Score = 182 bits (463), Expect = 2e-45
Identities = 114/393 (29%), Positives = 188/393 (47%), Gaps = 37/393 (9%)
Query: 1094 LVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIH 1153
LV + QC W C +G +++ C+C
Sbjct: 625 LVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCN------------------ 666
Query: 1154 LHTHYVMAKVIVIPNPVDLR--LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211
H + + V+P V++ + + + NPV + + ++ YV WA +D+ D
Sbjct: 667 -HLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQAD 725
Query: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271
+ V VL DNDP YL+ ++TG R + T A V + L G+ S+ H L P
Sbjct: 726 MQ-KVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
T RG ++ FLLTT + LG++HS+R+WH+N G SPSWY+S++ V ++ + W F+C
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388
WL+V D LDR F E + + F + ++++W SI F R+Q
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRIQ 904
Query: 1389 RLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMR-------SMMIGIESVLITIPVQ 1441
RLSCC+ +LL +++ N+MF+ +N T ++ + MR +++ I + +I P+
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKIN---STTAKRDEQMRPFAVAWSELLVSIHTAVILFPIN 961
Query: 1442 LLITFLFTCSQRKPQADLKEVSPQKHPLMSEAS 1474
L+I LF + PQ L P + +S+AS
Sbjct: 962 LVIGRLFPLIE--PQETLPLFPPIQASCLSDAS 992
Score = 77.0 bits (188), Expect = 2e-13
Identities = 72/267 (26%), Positives = 114/267 (42%), Gaps = 23/267 (8%)
Query: 1552 SEQHPSQK-------DLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGY 1604
+EQ PS++ ++ KK L W V W L+ TS S+FF Y L
Sbjct: 1122 TEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYRLELSK 1181
Query: 1605 DKSIEWLFASFCSFCQSVLLVQPSKII----LLSGFRTNKPKYCKNLSWSTKYKYTEIRL 1660
D++ W+ + S Q++ + QP K++ L S + P+ K TK + +
Sbjct: 1182 DQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTK-RILALLA 1240
Query: 1661 DGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIF 1720
P + + V + P E R K+KK K IL +F
Sbjct: 1241 KCSSSVPGSRDKNNPVYV---APAINSPTKHPE-RTLKKKKLFK-----LTGDILVQILF 1291
Query: 1721 LALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDL-NPT 1779
L LL+ I ++++ FY +Q I FS + + L+D Y W N +LLP L+ D
Sbjct: 1292 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYGDYRGKN 1351
Query: 1780 FLPESSSKILGLPLMRQV-RAKSSEKM 1805
+ E S G+ L+ Q+ R K+ EK+
Sbjct: 1352 AVLEPSHCKCGVQLIFQIPRTKTYEKV 1378
Score = 68.6 bits (166), Expect = 7e-11
Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 6/255 (2%)
Query: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLA---YVVDEGCIIMQERA 1991
F G TS+ L SF+ +K ++ ++ +I++L Y +GC + Q++
Sbjct: 1436 FSYIMRGAFFTSLRLESFTSLQMSKKGC--VWSIISQVIYYLLVCYYAFIQGCQLKQQKW 1493
Query: 1992 SYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMR 2051
+ N+L+ ++ I +L+ L ++ L + Y + + FI F+ +V+
Sbjct: 1494 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAAT 1553
Query: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111
++GF + L ++ R +R+ R + A + ++ + Y L+F
Sbjct: 1554 HLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLF 1613
Query: 2112 GQHEWNYSNLIHSTQTVFSYCVS-AFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAV 2170
G +Y S TV + + Q F+ + +LG + + +++M+ V+INLF +
Sbjct: 1614 GCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSA 1673
Query: 2171 ILSAYEEMKQPVYEE 2185
IL A+ + ++ + +E
Sbjct: 1674 ILMAFGKERKSLKKE 1688
>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1731
Score = 182 bits (463), Expect = 2e-45
Identities = 114/393 (29%), Positives = 188/393 (47%), Gaps = 37/393 (9%)
Query: 1094 LVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIH 1153
LV + QC W C +G +++ C+C
Sbjct: 625 LVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCN------------------ 666
Query: 1154 LHTHYVMAKVIVIPNPVDLR--LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211
H + + V+P V++ + + + NPV + + ++ YV WA +D+ D
Sbjct: 667 -HLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQAD 725
Query: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271
+ V VL DNDP YL+ ++TG R + T A V + L G+ S+ H L P
Sbjct: 726 MQ-KVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
T RG ++ FLLTT + LG++HS+R+WH+N G SPSWY+S++ V ++ + W F+C
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388
WL+V D LDR F E + + F + ++++W SI F R+Q
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRIQ 904
Query: 1389 RLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMR-------SMMIGIESVLITIPVQ 1441
RLSCC+ +LL +++ N+MF+ +N T ++ + MR +++ I + +I P+
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKIN---STTAKRDEQMRPFAVAWSELLVSIHTAVILFPIN 961
Query: 1442 LLITFLFTCSQRKPQADLKEVSPQKHPLMSEAS 1474
L+I LF + PQ L P + +S+AS
Sbjct: 962 LVIGRLFPLIE--PQETLPLFPPIQASCLSDAS 992
Score = 76.6 bits (187), Expect = 2e-13
Identities = 70/267 (26%), Positives = 115/267 (43%), Gaps = 24/267 (8%)
Query: 1552 SEQHPSQK-------DLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGY 1604
+EQ PS++ ++ KK L W V W L+ TS S+FF Y L
Sbjct: 1122 TEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSK 1181
Query: 1605 DKSIEWLFASFCSFCQSVLLVQPSKII----LLSGFRTNKPKYCKNLSWSTKYKYTEIRL 1660
D++ W+ + S Q++ + QP K++ L S + P+ K + + T+ L
Sbjct: 1182 DQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK------ENEXTKRIL 1235
Query: 1661 DGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIF 1720
+ + D+ + T+ R K+KK K IL +F
Sbjct: 1236 ALLAKCSSSVPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFK-----LTGDILVQILF 1290
Query: 1721 LALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDL-NPT 1779
L LL+ I ++++ FY +Q I FS + + L+D Y W N +LLP L+ D
Sbjct: 1291 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYGDYRGKN 1350
Query: 1780 FLPESSSKILGLPLMRQV-RAKSSEKM 1805
+ E S G+ L+ Q+ R K+ EK+
Sbjct: 1351 AVLEPSHCKCGVQLIFQIPRTKTYEKV 1377
Score = 68.6 bits (166), Expect = 7e-11
Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 6/255 (2%)
Query: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLA---YVVDEGCIIMQERA 1991
F G TS+ L SF+ +K ++ ++ +I++L Y +GC + Q++
Sbjct: 1435 FSYIMRGAFFTSLRLESFTSLQMSKKGC--VWSIISQVIYYLLVCYYAFIQGCQLKQQKW 1492
Query: 1992 SYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMR 2051
+ N+L+ ++ I +L+ L ++ L + Y + + FI F+ +V+
Sbjct: 1493 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAAT 1552
Query: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111
++GF + L ++ R +R+ R + A + ++ + Y L+F
Sbjct: 1553 HLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLF 1612
Query: 2112 GQHEWNYSNLIHSTQTVFSYCVS-AFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAV 2170
G +Y S TV + + Q F+ + +LG + + +++M+ V+INLF +
Sbjct: 1613 GCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSA 1672
Query: 2171 ILSAYEEMKQPVYEE 2185
IL A+ + ++ + +E
Sbjct: 1673 ILMAFGKERKSLKKE 1687
>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
Length = 1731
Score = 182 bits (462), Expect = 3e-45
Identities = 114/393 (29%), Positives = 188/393 (47%), Gaps = 37/393 (9%)
Query: 1094 LVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIH 1153
LV + QC W C +G +++ C+C
Sbjct: 625 LVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCN------------------ 666
Query: 1154 LHTHYVMAKVIVIPNPVDLR--LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211
H + + V+P V++ + + + NPV + + ++ YV WA +D+ D
Sbjct: 667 -HLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQAD 725
Query: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271
+ V VL DNDP YL+ ++TG R + T A V + L G+ S+ H L P
Sbjct: 726 MQ-KVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
T RG ++ FLLTT + LG++HS+R+WH+N G SPSWY+S++ V ++ + W F+C
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388
WL+V D LDR F E + + F + ++++W SI F R+Q
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
Query: 1389 RLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMR-------SMMIGIESVLITIPVQ 1441
RLSCC+ +LL +++ N+MF+ +N T ++ + MR +++ I + +I P+
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKIN---STTAKRDEQMRPFAVAWSELLVSIHTAVILFPIN 961
Query: 1442 LLITFLFTCSQRKPQADLKEVSPQKHPLMSEAS 1474
L+I LF + PQ L P + +S+AS
Sbjct: 962 LVIGRLFPLIE--PQETLPLFPPIQASCLSDAS 992
Score = 76.6 bits (187), Expect = 2e-13
Identities = 70/267 (26%), Positives = 115/267 (43%), Gaps = 24/267 (8%)
Query: 1552 SEQHPSQK-------DLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGY 1604
+EQ PS++ ++ KK L W V W L+ TS S+FF Y L
Sbjct: 1122 TEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSK 1181
Query: 1605 DKSIEWLFASFCSFCQSVLLVQPSKII----LLSGFRTNKPKYCKNLSWSTKYKYTEIRL 1660
D++ W+ + S Q++ + QP K++ L S + P+ K + + T+ L
Sbjct: 1182 DQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK------ENEXTKRIL 1235
Query: 1661 DGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIF 1720
+ + D+ + T+ R K+KK K IL +F
Sbjct: 1236 ALLAKCSSSVPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFK-----LTGDILVQILF 1290
Query: 1721 LALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDL-NPT 1779
L LL+ I ++++ FY +Q I FS + + L+D Y W N +LLP L+ D
Sbjct: 1291 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYGDYRGKN 1350
Query: 1780 FLPESSSKILGLPLMRQV-RAKSSEKM 1805
+ E S G+ L+ Q+ R K+ EK+
Sbjct: 1351 AVLEPSHCKCGVQLIFQIPRTKTYEKV 1377
Score = 68.6 bits (166), Expect = 7e-11
Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 6/255 (2%)
Query: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLA---YVVDEGCIIMQERA 1991
F G TS+ L SF+ +K ++ ++ +I++L Y +GC + Q++
Sbjct: 1435 FSYIMRGAFFTSLRLESFTSLQMSKKGC--VWSIISQVIYYLLVCYYAFIQGCQLKQQKW 1492
Query: 1992 SYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMR 2051
+ N+L+ ++ I +L+ L ++ L + Y + + FI F+ +V+
Sbjct: 1493 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAAT 1552
Query: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111
++GF + L ++ R +R+ R + A + ++ + Y L+F
Sbjct: 1553 HLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLF 1612
Query: 2112 GQHEWNYSNLIHSTQTVFSYCVS-AFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAV 2170
G +Y S TV + + Q F+ + +LG + + +++M+ V+INLF +
Sbjct: 1613 GCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSA 1672
Query: 2171 ILSAYEEMKQPVYEE 2185
IL A+ + ++ + +E
Sbjct: 1673 ILMAFGKERKSLKKE 1687
>gi|31559825 polycystin 1-like 3 [Homo sapiens]
Length = 1732
Score = 182 bits (462), Expect = 3e-45
Identities = 114/393 (29%), Positives = 188/393 (47%), Gaps = 37/393 (9%)
Query: 1094 LVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIH 1153
LV + QC W C +G +++ C+C
Sbjct: 625 LVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCN------------------ 666
Query: 1154 LHTHYVMAKVIVIPNPVDLR--LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211
H + + V+P V++ + + + NPV + + ++ YV WA +D+ D
Sbjct: 667 -HLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQAD 725
Query: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271
+ V VL DNDP YL+ ++TG R + T A V + L G+ S+ H L P
Sbjct: 726 MQ-KVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
T RG ++ FLLTT + LG++HS+R+WH+N G SPSWY+S++ V ++ + W F+C
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388
WL+V D LDR F E + + F + ++++W SI F R+Q
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
Query: 1389 RLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMR-------SMMIGIESVLITIPVQ 1441
RLSCC+ +LL +++ N+MF+ +N T ++ + MR +++ I + +I P+
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKIN---STTAKRDEQMRPFAVAWSELLVSIHTAVILFPIN 961
Query: 1442 LLITFLFTCSQRKPQADLKEVSPQKHPLMSEAS 1474
L+I LF + PQ L P + +S+AS
Sbjct: 962 LVIGRLFPLIE--PQETLPLFPPIQASCLSDAS 992
Score = 77.8 bits (190), Expect = 1e-13
Identities = 72/267 (26%), Positives = 114/267 (42%), Gaps = 23/267 (8%)
Query: 1552 SEQHPSQK-------DLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGY 1604
+EQ PS++ ++ KK L W V W L+ TS S+FF Y L
Sbjct: 1122 TEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSK 1181
Query: 1605 DKSIEWLFASFCSFCQSVLLVQPSKII----LLSGFRTNKPKYCKNLSWSTKYKYTEIRL 1660
D++ W+ + S Q++ + QP K++ L S + P+ K TK + +
Sbjct: 1182 DQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTK-RILALLA 1240
Query: 1661 DGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIF 1720
P + + V + P E R K+KK K IL +F
Sbjct: 1241 KCSSSVPGSRDKNNPVYV---APAINSPTKHPE-RTLKKKKLFK-----LTGDILVQILF 1291
Query: 1721 LALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDL-NPT 1779
L LL+ I ++++ FY +Q I FS + + L+D Y W N +LLP L+ D
Sbjct: 1292 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYGDYRGKN 1351
Query: 1780 FLPESSSKILGLPLMRQV-RAKSSEKM 1805
+ E S G+ L+ Q+ R K+ EK+
Sbjct: 1352 AVLEPSHCKCGVQLIFQIPRTKTYEKV 1378
Score = 68.6 bits (166), Expect = 7e-11
Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 6/255 (2%)
Query: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLA---YVVDEGCIIMQERA 1991
F G TS+ L SF+ +K ++ ++ +I++L Y +GC + Q++
Sbjct: 1436 FSYIMRGAFFTSLRLESFTSLQMSKKGC--VWSIISQVIYYLLVCYYAFIQGCQLKQQKW 1493
Query: 1992 SYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMR 2051
+ N+L+ ++ I +L+ L ++ L + Y + + FI F+ +V+
Sbjct: 1494 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAAT 1553
Query: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111
++GF + L ++ R +R+ R + A + ++ + Y L+F
Sbjct: 1554 HLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLF 1613
Query: 2112 GQHEWNYSNLIHSTQTVFSYCVS-AFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAV 2170
G +Y S TV + + Q F+ + +LG + + +++M+ V+INLF +
Sbjct: 1614 GCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSA 1673
Query: 2171 ILSAYEEMKQPVYEE 2185
IL A+ + ++ + +E
Sbjct: 1674 ILMAFGKERKSLKKE 1688
>gi|19923084 polycystin-1L1 [Homo sapiens]
Length = 2849
Score = 151 bits (381), Expect = 8e-36
Identities = 208/932 (22%), Positives = 364/932 (39%), Gaps = 91/932 (9%)
Query: 1177 IKSLHQNPVTLFTVLFI---ILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYL 1233
I L +P L +FI ++LY L + D ++ G++ + + P L Y
Sbjct: 1741 ISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQL-YA 1799
Query: 1234 VTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDI 1293
V I TG R + + V++ L G S+ LS P R S +TF+L+ + LG +
Sbjct: 1800 VVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLL 1859
Query: 1294 HSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSV---DTTLDRTFHVTHPDE 1350
IR+WH++ G SP W++S + V+ L + W F Q WLS D ++R +T
Sbjct: 1860 RKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVER--ELTCLQG 1917
Query: 1351 RLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNL 1410
L + F+ + L H+W S+++ + + RL+ + LL C
Sbjct: 1918 GLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFS-LLCVYACLTALVAA 1976
Query: 1411 NRQEQTESRERKYMRSMMIGIESVLITIPVQLLITFLFTCSQRKP-QADLKEVSPQKHPL 1469
QEQ + S +G+ L+ P L++ LF S+ P A ++ SP +
Sbjct: 1977 GGQEQPHLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGA 2036
Query: 1470 MSEASEHWEEYLRKWHAYETAKVHPREVAKPASKGKPRLPKASPKATSKPKHRHRKAQIK 1529
+EA + R A E K + + + + + + A PK + A
Sbjct: 2037 QTEAPHGPNSWGRIPDAQEPRKQPASAILSGSGRAQRKAASDNGTACPAPKLQVHGADHS 2096
Query: 1530 TPETLGPNTNSNNNIEDDQDVHSEQHPSQKDLQQLKKKPRIVLPWWCVYVAWFLVFATSS 1589
+G + + Q PS + + R + PWW V W + S
Sbjct: 2097 RTSLMGKSHCCPPH---------TQAPSSGLEGLMPQWSRALQPWWSSAV-WAICGTASL 2146
Query: 1590 ISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKIILLS-GF----RTNKPKYC 1644
S F +G ++ ++WL S + + QP + L++ GF R + +
Sbjct: 2147 ACSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFT 2206
Query: 1645 KNLSWSTK--------YKYTEIRLDGMRMHPE---EMQRIHDQIVRIRGTRMYQPLTEDE 1693
++L +T+ +T + P+ E++++ + R R P ++ +
Sbjct: 2207 ESLCEATRDLDSELAERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQ 2266
Query: 1694 IRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRFSMD--- 1750
+R +++ R + R L I + L LLL +I D + NQ IR F+ +
Sbjct: 2267 LRGTRQRMRRESRTRAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARN 2326
Query: 1751 -LATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSK--------ILGLPLMRQVRAKS 1801
L + + D + W + LL L+ P+ + ++G ++RQ++
Sbjct: 2327 CLGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKV-F 2385
Query: 1802 SEKMCLPAEKF---VQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTY 1858
+C P F +++SI C P+ G PE N +
Sbjct: 2386 PRHLCKPPRPFSALIEDSIPT---CSPEVG-GPE---------------------NPYLI 2420
Query: 1859 KPQGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLEL 1918
P+ G T +L + R + L L+ S W+D T AV +
Sbjct: 2421 DPENQNVTLNGPGGCGTREDCVLSL----GRTRTEAHTALSRLRASMWIDRSTRAVSVHF 2476
Query: 1919 TTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAY 1978
T +NP LF S+S+ E+ G + S + SFS+ R SA Y + + FLA
Sbjct: 2477 TLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIF---RSDSALQYHLMLPQLVFLAL 2533
Query: 1979 VVDEGCIIMQER-----ASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGII-RFYLS 2032
+ C+ + SY R N L ++ + + LA + +F+
Sbjct: 2534 SLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGDVTNQFHRG 2593
Query: 2033 NPEDFIPFHAVSQVDHIMRIILGFLLFLTILK 2064
F+ ++ + R + G LLFL LK
Sbjct: 2594 LCRAFMDLTLMASWNQRARWLRGILLFLFTLK 2625
>gi|4505835 polycystin 2 [Homo sapiens]
Length = 968
Score = 129 bits (324), Expect = 3e-29
Identities = 113/511 (22%), Positives = 218/511 (42%), Gaps = 67/511 (13%)
Query: 1711 LSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRF---------SMDLATVTKLEDIY 1761
L ++T+ +FL +L IL + ++ +YY + + F + T++ +ED +
Sbjct: 221 LRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFW 280
Query: 1762 RWLNSVLLPLLHNDLNPTFLPESSSK--------ILGLPLMRQVRAKSSEKMCLPAEKFV 1813
++ LL L+ + P+ E+ ++ +LG+P +RQ+R ++ +
Sbjct: 281 KFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCS-------I 333
Query: 1814 QNSIRREI-HCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKPQGTQWLYYS--- 1869
+R EI C+ Y + ED + GT W+Y S
Sbjct: 334 PQDLRDEIKECYDVYSVSSEDRAPFG--------------------PRNGTAWIYTSEKD 373
Query: 1870 ------YGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTTFNP 1923
+G++ TY GY Y + R + ++ L+++ WLD T A ++ + +N
Sbjct: 374 LNGSSHWGIIATYSGAGY--YLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNA 431
Query: 1924 DINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAY-VVDE 1982
+INLFC + ++ E G V S L + + I FF+ Y VV+E
Sbjct: 432 NINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEE 491
Query: 1983 GCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHA 2042
I + Y RS +N L+ + + V I + + + +++F L + F F
Sbjct: 492 ILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQF-LEDQNTFPNFEH 550
Query: 2043 VS----QVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSV 2098
++ Q ++I + + F +++ + K + ++R + L G M F++
Sbjct: 551 LAYWQIQFNNIAAVTV-FFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFII-- 607
Query: 2099 YFFVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSN-NRILGVLFLSSFML 2157
F Y YLVFG ++S T F + E NR+LG ++ ++F+
Sbjct: 608 -FLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVF 666
Query: 2158 VMICVLINLFQAVILSAYEEMKQPVYEEPSD 2188
M +L+N+F A+I Y E+K + ++ ++
Sbjct: 667 FMFFILLNMFLAIINDTYSEVKSDLAQQKAE 697
>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
Length = 805
Score = 128 bits (321), Expect = 7e-29
Identities = 111/488 (22%), Positives = 199/488 (40%), Gaps = 37/488 (7%)
Query: 1711 LSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRF-------SMDLATVTKLEDIYRW 1763
L +L + +FL + +L + + +YY + + + F + ++ + D + +
Sbjct: 101 LRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDF 160
Query: 1764 LNSVLLPLLH--NDLNPTFLPESS-------SKILGLPLMRQVRAKSSEKMCLPAEKFVQ 1814
LL L+ N L S + +LG+P +RQ++ ++ C+ E F +
Sbjct: 161 AQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDS--CVVHEDFRE 218
Query: 1815 NSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKPQGTQWLYYSYGLLH 1874
+ + C+ Y D E+ + F + +TY Q + +G L
Sbjct: 219 DILS----CYDVYSPDKEEQLPFGPF-----------NGTAWTYHSQDELGGFSHWGRLT 263
Query: 1875 TYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTTFNPDINLFCSISVI 1934
+Y GGY Y R S L+ LQE WLD T V ++ + +N +INLFC + ++
Sbjct: 264 SYSGGGY--YLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLV 321
Query: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIY-LYVAILIFFLAYVVDEGCIIMQERASY 1993
E G S + + L + I V +F YVV+E + R Y
Sbjct: 322 VEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRY 381
Query: 1994 VRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRII 2053
+ S++N+L+ + + V + + + ++ L P + F ++ +
Sbjct: 382 LSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNM 441
Query: 2054 LGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQ 2113
LF +K +Y F + + I A + + FF Y GYL+FG
Sbjct: 442 NAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGT 501
Query: 2114 HEWNYSNLIHSTQTVFSYCVSAFQNTEFSN-NRILGVLFLSSFMLVMICVLINLFQAVIL 2172
N+S I T F + F N NRILG + +++ + VL+N+F A+I
Sbjct: 502 QVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIIN 561
Query: 2173 SAYEEMKQ 2180
Y E+K+
Sbjct: 562 DTYSEVKE 569
>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
Length = 613
Score = 110 bits (276), Expect = 1e-23
Identities = 110/494 (22%), Positives = 209/494 (42%), Gaps = 49/494 (9%)
Query: 1711 LSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRF---------SMDLATVTKLEDIY 1761
L +L +FIFL L IL + + +Y N+ + F + ++ + D +
Sbjct: 29 LQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFW 88
Query: 1762 RWLNSVLLPLLHNDL----NPTFLPESSSKI------LGLPLMRQVRAKSSEKMCLPAEK 1811
+++ LL L+ D + ++SS+I LG+P +RQ++ +++ C
Sbjct: 89 KFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNT--CKVYSS 146
Query: 1812 FVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKPQGTQWLYYSYG 1871
F S+ E C+ KY ED N+ G + + +TN + W +G
Sbjct: 147 F--QSLMSE--CYGKYTSANEDLSNF-GLQINTEWRYSTSNTN--------SPW---HWG 190
Query: 1872 LLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTTFNPDINLFCSI 1931
L Y +GGY F + + + + +L+ ++W+ T + ++ + +N ++NLFC I
Sbjct: 191 FLGVYRNGGYI--FTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCII 248
Query: 1932 SVIFEVSQLGVVNTSISLHSFSLADFDRK-----ASAEIYLYVAILIFFLAYVVDEGCII 1986
++ E G + TS +S L + AS EI IF + E I
Sbjct: 249 RLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEI----TFCIFLFVFTTQEVKKI 304
Query: 1987 MQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQV 2046
+ +++Y +S++N L L + V + + ++ L + E + F+ ++
Sbjct: 305 KEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACW 364
Query: 2047 DHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAF 2106
I+ +F +K ++ F + + + I A + + FF Y
Sbjct: 365 HIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQL 424
Query: 2107 GYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSN-NRILGVLFLSSFMLVMICVLIN 2165
G+LVFG ++S +S F + F N ILG ++ +F+ + VL+N
Sbjct: 425 GFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLN 484
Query: 2166 LFQAVILSAYEEMK 2179
+F A+I Y E+K
Sbjct: 485 MFLAIINDTYSEVK 498
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 103 bits (256), Expect = 2e-21
Identities = 128/558 (22%), Positives = 217/558 (38%), Gaps = 77/558 (13%)
Query: 1571 VLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKI 1630
+LP WC +A L +++ + G ++ S+ WL +S SF S L +P K+
Sbjct: 3548 LLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKV 3607
Query: 1631 ILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQI----VRIRGTRMY 1686
+L + + L R+HP+E + + V R R+
Sbjct: 3608 LLEALY---------------------FSLVAKRLHPDEDDTLVESPAVTPVSARVPRVR 3646
Query: 1687 QP------LTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN 1740
P L ++E R KR + R L+++ L LL+ L+ C +
Sbjct: 3647 PPHGFALFLAKEEARKVKRLHGMLRSLLVYM---------LFLLVTLLASYGDASCHGHA 3697
Query: 1741 QFIRDRFSMDLAT-----VTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMR 1795
++ +L + +T+ E+++ W+ VLLP +H + SS LG P +R
Sbjct: 3698 YRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGN--------QSSPELGPPRLR 3749
Query: 1796 QVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNG 1855
QVR + + P + V Y + E N SG W +
Sbjct: 3750 QVRLQEALYPDPPGPR-VHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGA---- 3804
Query: 1856 FTYKPQGTQWLYYSYGLLHTYGSGGYA--LYFFPEQQRFNSTLRLKELQESNWLDEKTWA 1913
+S+G Y SGGY L E+ R RL+ LQ NWLD ++ A
Sbjct: 3805 ------------WSWGSCAVYDSGGYVQELGLSLEESRD----RLRFLQLHNWLDNRSRA 3848
Query: 1914 VVLELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILI 1973
V LELT ++P + L ++++ E G ++S+ F+L S + V +L+
Sbjct: 3849 VFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLL 3908
Query: 1974 FFLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLA-TGIIRFYLS 2032
F + + V E +E V + + L + ++ L + A RF
Sbjct: 3909 FAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRG 3968
Query: 2033 NPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHM 2092
P F F V+Q+ R + LLFL ++K + RF + + + ALP + +
Sbjct: 3969 RPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGV 4028
Query: 2093 AFVVSVYFFVYMAFGYLV 2110
+ V Y L+
Sbjct: 4029 TLGLVVLGVAYAQLAILL 4046
Score = 100 bits (249), Expect = 2e-20
Identities = 74/285 (25%), Positives = 125/285 (43%), Gaps = 21/285 (7%)
Query: 1183 NPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRW 1242
N + + T ++ Y+ +A D++D RG I P Y + + TG
Sbjct: 3074 NYIVMLTCAVCLVTYMVMAAILHKLDQLDAS-RGRAI--PFCGQRGRFKYEILVKTGWGR 3130
Query: 1243 GSGTRANVFVQLRGTVSTSDVHCLSHPHFT---TLYRGSINTFLLTTKSDLGDIHSIRVW 1299
GSGT A+V + L G S S H H +R S++ F + T LG + IRVW
Sbjct: 3131 GSGTTAHVGIMLYGVDSRS-----GHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVW 3185
Query: 1300 HNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDT-----TLDRTFHVTHPDERLTR 1354
H+N+G SP+W+L + V +L + F+ WLSV+T +++ L
Sbjct: 3186 HDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRF 3245
Query: 1355 KDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQE 1414
+ ++ H+W SI+ F R+QR +CC+ ++ L N +++
Sbjct: 3246 RRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDS 3305
Query: 1415 QTESRERKYMR-----SMMIGIESVLITIPVQLLITFLFTCSQRK 1454
+ + ++ +G+ S ++ PV L I FLF S+ K
Sbjct: 3306 AYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSK 3350
Score = 72.0 bits (175), Expect = 6e-12
Identities = 141/625 (22%), Positives = 243/625 (38%), Gaps = 80/625 (12%)
Query: 163 SPRSAAPGPRPQQGFVARTECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRI 222
SP PR + ++ G RV + A N S +++V+ Q+ AC V +
Sbjct: 2100 SPGQDTDEPRAEHSYLR------PGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDV 2153
Query: 223 NTDQKGAPVRLSMQAEAT--INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLP 280
P+++ M+ + A V L W+V+ + Q P + LP
Sbjct: 2154 VL-----PLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASC-QRPGRPARVALP 2207
Query: 281 QLEIRNSPLFIHIPNNSLQWGVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVM 340
+++ L + P +L G Y F F VS G+ + + S V + L ++
Sbjct: 2208 GVDVSRPRLVL--PRLALPVGHYCFVFVVSF--GDTPLTQ---SIQANVTVAPERLVPII 2260
Query: 341 LGDANITANFTEQLILDGSTSSDPD-ADSPLQGLQFFWYC-TTDPRNYGGDRIILGSKEV 398
G + + T L+LDGS S DP+ D L F W C + R GG + G +
Sbjct: 2261 EGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPR-- 2318
Query: 399 CHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVIRKDSR-TAFSDKRVHVLQGPKAI 457
+T+ E L Y F + + K R +++ V + G I
Sbjct: 2319 -------------GSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPI 2365
Query: 458 AHITCIENCERNFIVSDRFSLFL----NCTNCASRDFY-KWSILSSSGGEMLFDWMGETV 512
+ C+ +C+ + S ++ C NC+S +W+ + S ++ D T
Sbjct: 2366 VSLECV-SCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLD-ETTTS 2423
Query: 513 TGRNGAYLSIKAFAFRHFLEAEFSISLYLACW--SGVTSVFRHSFIINHGPQIGECKINP 570
TG G L ++ R F++++ G S+ N P G C++ P
Sbjct: 2424 TGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASI---RLSPNRPPLGGSCRLFP 2480
Query: 571 AKGI-ALITKFVVQCSNFRDKH---VPLTYKIIVSDLHSVG-EISSVKENTLGTILYLGP 625
+ AL TK +C+ + D PL Y +++ E V + +L +
Sbjct: 2481 LGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSY----- 2535
Query: 626 QSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNSSKTVLNQLLS 685
+ +PP F P + GL + Q D LGA + A + N S T L L
Sbjct: 2536 GAVLPPGFRP----HFEVGLAVVVQ--DQLGAAVVALNRSLAITLPEPNGSATGLTVWLH 2589
Query: 686 FTVGPSSLLSTLIQKKDFLPAGYLLYIVA--SVLNNMKTELPL-------RDDRVNLRKH 736
+S+L L+++ D P + Y +A +VLN + L + R R +RK+
Sbjct: 2590 GLT--ASVLPGLLRQAD--PQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKN 2645
Query: 737 LIDQSFLLPVSTLVEIGQVVMTITK 761
+ + L V T+ +I Q+ + +
Sbjct: 2646 ITETLVSLRVHTVDDIQQIAAALAQ 2670
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 103 bits (256), Expect = 2e-21
Identities = 128/558 (22%), Positives = 217/558 (38%), Gaps = 77/558 (13%)
Query: 1571 VLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKI 1630
+LP WC +A L +++ + G ++ S+ WL +S SF S L +P K+
Sbjct: 3549 LLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKV 3608
Query: 1631 ILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQI----VRIRGTRMY 1686
+L + + L R+HP+E + + V R R+
Sbjct: 3609 LLEALY---------------------FSLVAKRLHPDEDDTLVESPAVTPVSARVPRVR 3647
Query: 1687 QP------LTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN 1740
P L ++E R KR + R L+++ L LL+ L+ C +
Sbjct: 3648 PPHGFALFLAKEEARKVKRLHGMLRSLLVYM---------LFLLVTLLASYGDASCHGHA 3698
Query: 1741 QFIRDRFSMDLAT-----VTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMR 1795
++ +L + +T+ E+++ W+ VLLP +H + SS LG P +R
Sbjct: 3699 YRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGN--------QSSPELGPPRLR 3750
Query: 1796 QVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNG 1855
QVR + + P + V Y + E N SG W +
Sbjct: 3751 QVRLQEALYPDPPGPR-VHTCSAAGGFSTSDYDVGWESPHNGSGTWAYSAPDLLGA---- 3805
Query: 1856 FTYKPQGTQWLYYSYGLLHTYGSGGYA--LYFFPEQQRFNSTLRLKELQESNWLDEKTWA 1913
+S+G Y SGGY L E+ R RL+ LQ NWLD ++ A
Sbjct: 3806 ------------WSWGSCAVYDSGGYVQELGLSLEESRD----RLRFLQLHNWLDNRSRA 3849
Query: 1914 VVLELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILI 1973
V LELT ++P + L ++++ E G ++S+ F+L S + V +L+
Sbjct: 3850 VFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLL 3909
Query: 1974 FFLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLA-TGIIRFYLS 2032
F + + V E +E V + + L + ++ L + A RF
Sbjct: 3910 FAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRG 3969
Query: 2033 NPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHM 2092
P F F V+Q+ R + LLFL ++K + RF + + + ALP + +
Sbjct: 3970 RPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGV 4029
Query: 2093 AFVVSVYFFVYMAFGYLV 2110
+ V Y L+
Sbjct: 4030 TLGLVVLGVAYAQLAILL 4047
Score = 100 bits (249), Expect = 2e-20
Identities = 74/285 (25%), Positives = 125/285 (43%), Gaps = 21/285 (7%)
Query: 1183 NPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRW 1242
N + + T ++ Y+ +A D++D RG I P Y + + TG
Sbjct: 3074 NYIVMLTCAVCLVTYMVMAAILHKLDQLDAS-RGRAI--PFCGQRGRFKYEILVKTGWGR 3130
Query: 1243 GSGTRANVFVQLRGTVSTSDVHCLSHPHFT---TLYRGSINTFLLTTKSDLGDIHSIRVW 1299
GSGT A+V + L G S S H H +R S++ F + T LG + IRVW
Sbjct: 3131 GSGTTAHVGIMLYGVDSRS-----GHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVW 3185
Query: 1300 HNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDT-----TLDRTFHVTHPDERLTR 1354
H+N+G SP+W+L + V +L + F+ WLSV+T +++ L
Sbjct: 3186 HDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRF 3245
Query: 1355 KDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQE 1414
+ ++ H+W SI+ F R+QR +CC+ ++ L N +++
Sbjct: 3246 RRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDS 3305
Query: 1415 QTESRERKYMR-----SMMIGIESVLITIPVQLLITFLFTCSQRK 1454
+ + ++ +G+ S ++ PV L I FLF S+ K
Sbjct: 3306 AYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSK 3350
Score = 72.0 bits (175), Expect = 6e-12
Identities = 141/625 (22%), Positives = 243/625 (38%), Gaps = 80/625 (12%)
Query: 163 SPRSAAPGPRPQQGFVARTECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRI 222
SP PR + ++ G RV + A N S +++V+ Q+ AC V +
Sbjct: 2100 SPGQDTDEPRAEHSYLR------PGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDV 2153
Query: 223 NTDQKGAPVRLSMQAEAT--INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLP 280
P+++ M+ + A V L W+V+ + Q P + LP
Sbjct: 2154 VL-----PLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASC-QRPGRPARVALP 2207
Query: 281 QLEIRNSPLFIHIPNNSLQWGVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVM 340
+++ L + P +L G Y F F VS G+ + + S V + L ++
Sbjct: 2208 GVDVSRPRLVL--PRLALPVGHYCFVFVVSF--GDTPLTQ---SIQANVTVAPERLVPII 2260
Query: 341 LGDANITANFTEQLILDGSTSSDPD-ADSPLQGLQFFWYC-TTDPRNYGGDRIILGSKEV 398
G + + T L+LDGS S DP+ D L F W C + R GG + G +
Sbjct: 2261 EGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPR-- 2318
Query: 399 CHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVIRKDSR-TAFSDKRVHVLQGPKAI 457
+T+ E L Y F + + K R +++ V + G I
Sbjct: 2319 -------------GSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPI 2365
Query: 458 AHITCIENCERNFIVSDRFSLFL----NCTNCASRDFY-KWSILSSSGGEMLFDWMGETV 512
+ C+ +C+ + S ++ C NC+S +W+ + S ++ D T
Sbjct: 2366 VSLECV-SCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLD-ETTTS 2423
Query: 513 TGRNGAYLSIKAFAFRHFLEAEFSISLYLACW--SGVTSVFRHSFIINHGPQIGECKINP 570
TG G L ++ R F++++ G S+ N P G C++ P
Sbjct: 2424 TGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASI---RLSPNRPPLGGSCRLFP 2480
Query: 571 AKGI-ALITKFVVQCSNFRDKH---VPLTYKIIVSDLHSVG-EISSVKENTLGTILYLGP 625
+ AL TK +C+ + D PL Y +++ E V + +L +
Sbjct: 2481 LGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSY----- 2535
Query: 626 QSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNSSKTVLNQLLS 685
+ +PP F P + GL + Q D LGA + A + N S T L L
Sbjct: 2536 GAVLPPGFRP----HFEVGLAVVVQ--DQLGAAVVALNRSLAITLPEPNGSATGLTVWLH 2589
Query: 686 FTVGPSSLLSTLIQKKDFLPAGYLLYIVA--SVLNNMKTELPL-------RDDRVNLRKH 736
+S+L L+++ D P + Y +A +VLN + L + R R +RK+
Sbjct: 2590 GLT--ASVLPGLLRQAD--PQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKN 2645
Query: 737 LIDQSFLLPVSTLVEIGQVVMTITK 761
+ + L V T+ +I Q+ + +
Sbjct: 2646 ITETLVSLRVHTVDDIQQIAAALAQ 2670
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sapiens]
Length = 1114
Score = 69.7 bits (169), Expect = 3e-11
Identities = 40/125 (32%), Positives = 70/125 (56%), Gaps = 6/125 (4%)
Query: 1225 DPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTT--LYRGSINTF 1282
+P D + Y V IFTG+ G+GT A V++ + G + + L T RG+ +TF
Sbjct: 344 EPLDIVLYSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTF 403
Query: 1283 LLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSV---DTTL 1339
++ +DLG I+ I++ H+N WY+ ++++ N + +LF+C +WLS+ D L
Sbjct: 404 IIEA-ADLGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRL 462
Query: 1340 DRTFH 1344
+R F+
Sbjct: 463 ERLFY 467
Score = 67.0 bits (162), Expect = 2e-10
Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 12/123 (9%)
Query: 1223 DNDPYDNLC---------YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCL--SHPHF 1271
DN+P DNL + VTI TG + +GT ANVF+ L GT + + L S +
Sbjct: 48 DNNPLDNLALEQKDKSTTFSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNS 107
Query: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
R SI F + T DLGD+ +R+ H+N G++P W++ ++V+ F C +
Sbjct: 108 DKFERDSIEIFTVETL-DLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGR 166
Query: 1332 WLS 1334
WL+
Sbjct: 167 WLA 169
Score = 60.5 bits (145), Expect = 2e-08
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 1/116 (0%)
Query: 1220 VLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHP-HFTTLYRGS 1278
V+ + + + Y V + T G+GT ANVF+ + G S L ++ R +
Sbjct: 764 VIDEEEMMEWTSYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNN 823
Query: 1279 INTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLS 1334
+TF LG + +RVWH+N+G P W+LS + V++ + F C WLS
Sbjct: 824 TDTFNFPDMLSLGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS 879
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 18/137 (13%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTT--------LYRGSINTFL 1283
Y +T++T + +GT AN+F+ + G D C + T R S + F+
Sbjct: 197 YEITLYTSDVFAAGTDANIFIIIYGC----DAVCTQQKYLCTNKREQKQFFERKSASRFI 252
Query: 1284 LTTKSDLGDI-HSIRVWHNNEGRSPSWYLSRIKVENLF----SRHIWLFICQKWLSVDTT 1338
+ + D+G+I IR+ HNN G +P W+ S + + L F C +WL+
Sbjct: 253 VELE-DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSED 311
Query: 1339 LDRTFHVTHPDERLTRK 1355
+T P + T K
Sbjct: 312 DKKTIRELVPYDIFTEK 328
Score = 45.1 bits (105), Expect = 8e-04
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Y +T++TG G GT +N+F+ L G +++ L R +TF++ D+
Sbjct: 649 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKK-ARFEREQNDTFIMEIL-DIA 706
Query: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLS 1334
+R+ + G P W+L RI ++N+ + + +F WLS
Sbjct: 707 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749
Score = 31.6 bits (70), Expect = 9.2
Identities = 20/55 (36%), Positives = 25/55 (45%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTT 1286
Y V + TG G+GT ANVFV + G + L RGS + F L T
Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET 1099
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 69.7 bits (169), Expect = 3e-11
Identities = 40/125 (32%), Positives = 70/125 (56%), Gaps = 6/125 (4%)
Query: 1225 DPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTT--LYRGSINTF 1282
+P D + Y V IFTG+ G+GT A V++ + G + + L T RG+ +TF
Sbjct: 1455 EPLDIVLYSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTF 1514
Query: 1283 LLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSV---DTTL 1339
++ +DLG I+ I++ H+N WY+ ++++ N + +LF+C +WLS+ D L
Sbjct: 1515 IIEA-ADLGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRL 1573
Query: 1340 DRTFH 1344
+R F+
Sbjct: 1574 ERLFY 1578
Score = 67.0 bits (162), Expect = 2e-10
Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 12/123 (9%)
Query: 1223 DNDPYDNLC---------YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCL--SHPHF 1271
DN+P DNL + VTI TG + +GT ANVF+ L GT + + L S +
Sbjct: 1159 DNNPLDNLALEQKDKSTTFSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNS 1218
Query: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
R SI F + T DLGD+ +R+ H+N G++P W++ ++V+ F C +
Sbjct: 1219 DKFERDSIEIFTVETL-DLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGR 1277
Query: 1332 WLS 1334
WL+
Sbjct: 1278 WLA 1280
Score = 62.8 bits (151), Expect = 4e-09
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 2/134 (1%)
Query: 1202 FWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTS 1261
F ALY E+ + +++ Y Y V TG G+GT ANVF+ L G S
Sbjct: 15 FLALYEAELLNYASEDDEGELEHEYYKARVYEVVTATGDVRGAGTDANVFITLFGENGLS 74
Query: 1262 DVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFS 1321
L+ + +G+++ F + T +++G I+ +R+ H+N G + SWYL + V ++
Sbjct: 75 PKLQLTSKSKSAFEKGNVDVFRVRT-NNVGLIYKVRIEHDNTGLNASWYLDHVIVTDMKR 133
Query: 1322 RHI-WLFICQKWLS 1334
H+ + F C WLS
Sbjct: 134 PHLRYYFNCNNWLS 147
Score = 62.0 bits (149), Expect = 6e-09
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Y V ++TG G+GT A+VF+ + G + L + +G+ + F+L DLG
Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEK-DNFEKGAEDRFILDAP-DLG 231
Query: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVD 1336
+ I V HNN+G S W+LS+I +E++ ++ + F +WL++D
Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALD 276
Score = 60.5 bits (145), Expect = 2e-08
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 1/116 (0%)
Query: 1220 VLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHP-HFTTLYRGS 1278
V+ + + + Y V + T G+GT ANVF+ + G S L ++ R +
Sbjct: 1813 VIDEEEMMEWTSYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNN 1872
Query: 1279 INTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLS 1334
+TF LG + +RVWH+N+G P W+LS + V++ + F C WLS
Sbjct: 1873 TDTFNFPDMLSLGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS 1928
Score = 56.6 bits (135), Expect = 3e-07
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Y V + TG G+GT ANVFV + G + L RGS + F L T +LG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLETL-ELG 2152
Query: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWL 1333
++ +R+ H++ G W + +++V N + +F C +WL
Sbjct: 2153 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 2194
Score = 55.5 bits (132), Expect = 6e-07
Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Y V I+TG G+GT A V++Q+ G ++V LS R S +TF L +D+G
Sbjct: 816 YEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSS-RSKVFERASKDTFQLEA-ADVG 873
Query: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHI 1324
+++ +R+ H EG PSW++ + + +L R +
Sbjct: 874 EVYKLRLGHTGEGFGPSWFVDTVWLRHLVVREV 906
Score = 55.1 bits (131), Expect = 8e-07
Identities = 32/107 (29%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTV--STSDVHCLSHPHFTTLYRGSINTFLLTTKSD 1289
Y V + TG+ +GT ANV++ + G T + +G +TF + D
Sbjct: 1024 YEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA-ID 1082
Query: 1290 LGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVD 1336
LG + IR+ H+N G W+L RI + ++ + + F CQ+WL+V+
Sbjct: 1083 LGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVE 1129
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 18/137 (13%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTT--------LYRGSINTFL 1283
Y +T++T + +GT AN+F+ + G D C + T R S + F+
Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGC----DAVCTQQKYLCTNKREQKQFFERKSASRFI 1363
Query: 1284 LTTKSDLGDI-HSIRVWHNNEGRSPSWYLSRIKVENLF----SRHIWLFICQKWLSVDTT 1338
+ + D+G+I IR+ HNN G +P W+ S + + L F C +WL+
Sbjct: 1364 VELE-DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSED 1422
Query: 1339 LDRTFHVTHPDERLTRK 1355
+T P + T K
Sbjct: 1423 DKKTIRELVPYDIFTEK 1439
Score = 52.4 bits (124), Expect = 5e-06
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 1244 SGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNE 1303
+GT + +F+Q+ G +D L +P+ G I F + DLG + IRVWH+
Sbjct: 439 AGTNSPIFIQIYGQKGRTD-EILLNPNNKWFKPGIIEKFRIELP-DLGRFYKIRVWHDKR 496
Query: 1304 GRSPSWYLSRIKVENLFSRHIWLFICQKWLSVD 1336
W+L R+ + N ++ + F C +WL +
Sbjct: 497 SSGSGWHLERMTLMNTLNKDKYNFNCNRWLDAN 529
Score = 46.6 bits (109), Expect = 3e-04
Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTT--LYRGSINTFLLTTKSD 1289
Y VT+ TG G+GT ANV++ L G V + L + T +G+ + F + + +
Sbjct: 555 YHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIESVT- 613
Query: 1290 LGDIHSIRVWHNNEGRSPSWYLSRIKV--ENLFSRHIWLFICQKWLSVD 1336
+ ++ +R+ H+ +G WYL R+ V E F C +WL D
Sbjct: 614 MRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKD 662
Score = 45.1 bits (105), Expect = 8e-04
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Y +T++TG G GT +N+F+ L G +++ L R +TF++ D+
Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKK-ARFEREQNDTFIMEIL-DIA 1755
Query: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLS 1334
+R+ + G P W+L RI ++N+ + + +F WLS
Sbjct: 1756 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798
Score = 43.9 bits (102), Expect = 0.002
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
Query: 1205 LYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTS--D 1262
L +D+ D L ++ + N Y +++ TG G+ T + V+++L G S +
Sbjct: 659 LDKDKDDGQLVRELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQ 718
Query: 1263 VHCLSHPHFTTLY-RGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFS 1321
V +S + + RG ++ F L T + +G+I+ + + H++ G SW+L +++
Sbjct: 719 VLLVSDNNLKDYFERGRVDEFTLETLN-IGNINRLVIGHDSTGMHASWFLGSVQIRVPRQ 777
Query: 1322 RHIWLFICQKWLSVDTTLDRTFHVTHPDE 1350
+ F +WL + R +P E
Sbjct: 778 GKQYTFPANRWLDKNQADGRLEVELYPSE 806
Score = 40.8 bits (94), Expect = 0.015
Identities = 25/107 (23%), Positives = 48/107 (44%), Gaps = 7/107 (6%)
Query: 1230 LCYLVTIFTGSRWGSGTRANVFVQL---RGTVSTSDVHCLSHPHFTTLYRGSINTFLLTT 1286
+ Y+VT+FTG G+GT++ +++ + RG ++ + RG + F +
Sbjct: 296 ITYIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIFL----EGGVFDRGRTDIFHIEL 351
Query: 1287 KSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWL 1333
L + + V H N G + W+ ++ + F+ F C WL
Sbjct: 352 AVLLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNWL 398
>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
Length = 674
Score = 65.5 bits (158), Expect = 6e-10
Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Y VT+ TGS+W +GT +++ L G+ S+ H L P + RG+++++ +T +LG
Sbjct: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63
Query: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVD 1336
+I +R+ + WYL I ++ +I F C +W++ D
Sbjct: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYI-EFPCYRWITGD 107
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sapiens]
Length = 512
Score = 60.5 bits (145), Expect = 2e-08
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 1/116 (0%)
Query: 1220 VLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHP-HFTTLYRGS 1278
V+ + + + Y V + T G+GT ANVF+ + G S L ++ R +
Sbjct: 114 VIDEEEMMEWTSYTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNN 173
Query: 1279 INTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLS 1334
+TF LG + +RVWH+N+G P W+LS + V++ + F C WLS
Sbjct: 174 TDTFNFPDMLSLGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLS 229
Score = 56.6 bits (135), Expect = 3e-07
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
Query: 1232 YLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLG 1291
Y V + TG G+GT ANVFV + G + L RGS + F L T +LG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLETL-ELG 453
Query: 1292 DIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWL 1333
++ +R+ H++ G W + +++V N + +F C +WL
Sbjct: 454 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 495
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 1234 VTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDI 1293
+T++TG G GT +N+F+ L G +++ L R +TF++ D+
Sbjct: 1 MTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQLDKKK-ARFEREQNDTFIMEIL-DIAPF 58
Query: 1294 HSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLS 1334
+R+ + G P W+L RI ++N+ + + +F WLS
Sbjct: 59 TKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 99
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 57.0 bits (136), Expect = 2e-07
Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 1197 YVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLC-YLVTIFTGSRWGSGTRANVFVQLR 1255
YV + W L RD+ D + +L P + Y V + TG W +GT ANV++ +
Sbjct: 8 YVPVQRW-LARDQEDGEICREFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISIH 66
Query: 1256 GTVSTSDVHCL--SHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSR 1313
G + L S F L RG +TF L LGD+ I + H+ G W+L
Sbjct: 67 GEKGDTGSRQLFRSKSSFNFL-RGQTDTFFLEAVH-LGDLCKIVIGHDGLGPGNGWFLDD 124
Query: 1314 IKVENLFSRHIWLFICQKWL 1333
+ +++ + + + F C +WL
Sbjct: 125 VVIKDPTTNYEYAFFCHRWL 144
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 57.0 bits (136), Expect = 2e-07
Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 1197 YVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLC-YLVTIFTGSRWGSGTRANVFVQLR 1255
YV + W L RD+ D + +L P + Y V + TG W +GT ANV++ +
Sbjct: 8 YVPVQRW-LARDQEDGEICREFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISIH 66
Query: 1256 GTVSTSDVHCL--SHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSR 1313
G + L S F L RG +TF L LGD+ I + H+ G W+L
Sbjct: 67 GEKGDTGSRQLFRSKSSFNFL-RGQTDTFFLEAVH-LGDLCKIVIGHDGLGPGNGWFLDD 124
Query: 1314 IKVENLFSRHIWLFICQKWL 1333
+ +++ + + + F C +WL
Sbjct: 125 VVIKDPTTNYEYAFFCHRWL 144
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 57.0 bits (136), Expect = 2e-07
Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 1197 YVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLC-YLVTIFTGSRWGSGTRANVFVQLR 1255
YV + W L RD+ D + +L P + Y V + TG W +GT ANV++ +
Sbjct: 8 YVPVQRW-LARDQEDGEICREFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISIH 66
Query: 1256 GTVSTSDVHCL--SHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSR 1313
G + L S F L RG +TF L LGD+ I + H+ G W+L
Sbjct: 67 GEKGDTGSRQLFRSKSSFNFL-RGQTDTFFLEAVH-LGDLCKIVIGHDGLGPGNGWFLDD 124
Query: 1314 IKVENLFSRHIWLFICQKWL 1333
+ +++ + + + F C +WL
Sbjct: 125 VVIKDPTTNYEYAFFCHRWL 144
>gi|10092597 mucolipin 1 [Homo sapiens]
Length = 580
Score = 55.8 bits (133), Expect = 5e-07
Identities = 35/143 (24%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 2049 IMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGY 2108
+ I+LG L + +RY FF++ + ++ ALP + V+V + Y G+
Sbjct: 385 VCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGW 444
Query: 2109 LVFGQHEWNYSNLIHSTQTVFS----------YCVSAFQNTEFSNNRILGVLFLSSFMLV 2158
+V G + + +L ++ +FS + Q S + L+L SF+ +
Sbjct: 445 IVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISL 504
Query: 2159 MICVLINLFQAVILSAYEEMKQP 2181
I ++++LF A+I AY+ +K P
Sbjct: 505 FIYMVLSLFIALITGAYDTIKHP 527
>gi|24496763 mucolipin 3 [Homo sapiens]
Length = 553
Score = 53.9 bits (128), Expect = 2e-06
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 12/162 (7%)
Query: 2049 IMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGY 2108
+ I+LG L L +RY FF L +QAALP + ++ + Y G+
Sbjct: 372 VCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGW 431
Query: 2109 LVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNR-------ILGVLFLSSFMLVMIC 2161
+V G + + +L ++ +FS F+ + + ++L SF+ + I
Sbjct: 432 IVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIY 491
Query: 2162 VLINLFQAVILSAYEEMKQPVYEE---PSDEVEAMTYLCRKL 2200
++++LF A+I YE +KQ Y++ P E+ C+ L
Sbjct: 492 MILSLFIALITDTYETIKQ--YQQDGFPETELRTFISECKDL 531
>gi|237512982 voltage-gated sodium channel type V alpha isoform f
[Homo sapiens]
Length = 1962
Score = 48.1 bits (113), Expect = 1e-04
Identities = 56/273 (20%), Positives = 111/273 (40%), Gaps = 64/273 (23%)
Query: 1954 LADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQE--RASYVRSVYNLLNFALKCIFTV 2011
+ + D ++ +I + I + F+A E CI+ R Y + +N+ +F + + V
Sbjct: 1492 MVETDDQSPEKINILAKINLLFVAIFTGE-CIVKLAALRHYYFTNSWNIFDFVVVILSIV 1550
Query: 2012 LIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRF 2071
VL + II+ Y +P F ++++ I+R+I G T+L L S
Sbjct: 1551 GTVL--------SDIIQKYFFSPTLFRVIR-LARIGRILRLIRGAKGIRTLLFALMMS-- 1599
Query: 2072 FYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW--------NYSNLIH 2123
LP + ++ ++ + F+Y FG F +W N+ +
Sbjct: 1600 --------------LPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFAN 1645
Query: 2124 STQTVFS--------------------YCVSAFQNTEFSN----NRILGVLFLSSFMLVM 2159
S +F YC N+ S + +G+LF ++++++
Sbjct: 1646 SMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIIS 1705
Query: 2160 ICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
+++N++ A+IL A EE +P+ E+ D
Sbjct: 1706 FLIVVNMYIAIILENFSVATEESTEPLSEDDFD 1738
Score = 37.0 bits (84), Expect = 0.22
Identities = 34/162 (20%), Positives = 75/162 (46%), Gaps = 29/162 (17%)
Query: 2040 FHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQ---------RAIQAALPGIC 2090
F ++ + +M + L + L++L++ R R F +LA+ + I ++ +
Sbjct: 784 FDSIIVILSLMELGLSRMSNLSVLRSFRLLRVF---KLAKSWPTLNTLIKIIGNSVGALG 840
Query: 2091 HMAFVVSVYFFVYMAFGYLVFGQH-------------EWNYSNLIHSTQTVFSYCVSAFQ 2137
++ V+++ F++ G +FG++ W+ + H+ +F +
Sbjct: 841 NLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWI 900
Query: 2138 NTEFSNNRILG-VLFLSSFMLVMI---CVLINLFQAVILSAY 2175
T + + G L L F+LVM+ V++NLF A++LS++
Sbjct: 901 ETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSF 942
>gi|37622907 voltage-gated sodium channel type V alpha isoform a [Homo
sapiens]
Length = 2016
Score = 48.1 bits (113), Expect = 1e-04
Identities = 56/273 (20%), Positives = 111/273 (40%), Gaps = 64/273 (23%)
Query: 1954 LADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQE--RASYVRSVYNLLNFALKCIFTV 2011
+ + D ++ +I + I + F+A E CI+ R Y + +N+ +F + + V
Sbjct: 1546 MVETDDQSPEKINILAKINLLFVAIFTGE-CIVKLAALRHYYFTNSWNIFDFVVVILSIV 1604
Query: 2012 LIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRF 2071
VL + II+ Y +P F ++++ I+R+I G T+L L S
Sbjct: 1605 GTVL--------SDIIQKYFFSPTLFRVIR-LARIGRILRLIRGAKGIRTLLFALMMS-- 1653
Query: 2072 FYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW--------NYSNLIH 2123
LP + ++ ++ + F+Y FG F +W N+ +
Sbjct: 1654 --------------LPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFAN 1699
Query: 2124 STQTVFS--------------------YCVSAFQNTEFSN----NRILGVLFLSSFMLVM 2159
S +F YC N+ S + +G+LF ++++++
Sbjct: 1700 SMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIIS 1759
Query: 2160 ICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
+++N++ A+IL A EE +P+ E+ D
Sbjct: 1760 FLIVVNMYIAIILENFSVATEESTEPLSEDDFD 1792
Score = 37.0 bits (84), Expect = 0.22
Identities = 34/162 (20%), Positives = 75/162 (46%), Gaps = 29/162 (17%)
Query: 2040 FHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQ---------RAIQAALPGIC 2090
F ++ + +M + L + L++L++ R R F +LA+ + I ++ +
Sbjct: 784 FDSIIVILSLMELGLSRMSNLSVLRSFRLLRVF---KLAKSWPTLNTLIKIIGNSVGALG 840
Query: 2091 HMAFVVSVYFFVYMAFGYLVFGQH-------------EWNYSNLIHSTQTVFSYCVSAFQ 2137
++ V+++ F++ G +FG++ W+ + H+ +F +
Sbjct: 841 NLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWI 900
Query: 2138 NTEFSNNRILG-VLFLSSFMLVMI---CVLINLFQAVILSAY 2175
T + + G L L F+LVM+ V++NLF A++LS++
Sbjct: 901 ETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSF 942
>gi|30089970 voltage-gated sodium channel type V alpha isoform b [Homo
sapiens]
Length = 2015
Score = 48.1 bits (113), Expect = 1e-04
Identities = 56/273 (20%), Positives = 111/273 (40%), Gaps = 64/273 (23%)
Query: 1954 LADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQE--RASYVRSVYNLLNFALKCIFTV 2011
+ + D ++ +I + I + F+A E CI+ R Y + +N+ +F + + V
Sbjct: 1545 MVETDDQSPEKINILAKINLLFVAIFTGE-CIVKLAALRHYYFTNSWNIFDFVVVILSIV 1603
Query: 2012 LIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRF 2071
VL + II+ Y +P F ++++ I+R+I G T+L L S
Sbjct: 1604 GTVL--------SDIIQKYFFSPTLFRVIR-LARIGRILRLIRGAKGIRTLLFALMMS-- 1652
Query: 2072 FYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW--------NYSNLIH 2123
LP + ++ ++ + F+Y FG F +W N+ +
Sbjct: 1653 --------------LPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFAN 1698
Query: 2124 STQTVFS--------------------YCVSAFQNTEFSN----NRILGVLFLSSFMLVM 2159
S +F YC N+ S + +G+LF ++++++
Sbjct: 1699 SMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIIS 1758
Query: 2160 ICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
+++N++ A+IL A EE +P+ E+ D
Sbjct: 1759 FLIVVNMYIAIILENFSVATEESTEPLSEDDFD 1791
Score = 37.0 bits (84), Expect = 0.22
Identities = 34/162 (20%), Positives = 75/162 (46%), Gaps = 29/162 (17%)
Query: 2040 FHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQ---------RAIQAALPGIC 2090
F ++ + +M + L + L++L++ R R F +LA+ + I ++ +
Sbjct: 784 FDSIIVILSLMELGLSRMSNLSVLRSFRLLRVF---KLAKSWPTLNTLIKIIGNSVGALG 840
Query: 2091 HMAFVVSVYFFVYMAFGYLVFGQH-------------EWNYSNLIHSTQTVFSYCVSAFQ 2137
++ V+++ F++ G +FG++ W+ + H+ +F +
Sbjct: 841 NLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWI 900
Query: 2138 NTEFSNNRILG-VLFLSSFMLVMI---CVLINLFQAVILSAY 2175
T + + G L L F+LVM+ V++NLF A++LS++
Sbjct: 901 ETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSF 942
>gi|150417969 voltage-gated sodium channel type V alpha isoform d
[Homo sapiens]
Length = 1998
Score = 48.1 bits (113), Expect = 1e-04
Identities = 56/273 (20%), Positives = 111/273 (40%), Gaps = 64/273 (23%)
Query: 1954 LADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQE--RASYVRSVYNLLNFALKCIFTV 2011
+ + D ++ +I + I + F+A E CI+ R Y + +N+ +F + + V
Sbjct: 1528 MVETDDQSPEKINILAKINLLFVAIFTGE-CIVKLAALRHYYFTNSWNIFDFVVVILSIV 1586
Query: 2012 LIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRF 2071
VL + II+ Y +P F ++++ I+R+I G T+L L S
Sbjct: 1587 GTVL--------SDIIQKYFFSPTLFRVIR-LARIGRILRLIRGAKGIRTLLFALMMS-- 1635
Query: 2072 FYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW--------NYSNLIH 2123
LP + ++ ++ + F+Y FG F +W N+ +
Sbjct: 1636 --------------LPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFAN 1681
Query: 2124 STQTVFS--------------------YCVSAFQNTEFSN----NRILGVLFLSSFMLVM 2159
S +F YC N+ S + +G+LF ++++++
Sbjct: 1682 SMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIIS 1741
Query: 2160 ICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
+++N++ A+IL A EE +P+ E+ D
Sbjct: 1742 FLIVVNMYIAIILENFSVATEESTEPLSEDDFD 1774
Score = 37.0 bits (84), Expect = 0.22
Identities = 34/162 (20%), Positives = 75/162 (46%), Gaps = 29/162 (17%)
Query: 2040 FHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQ---------RAIQAALPGIC 2090
F ++ + +M + L + L++L++ R R F +LA+ + I ++ +
Sbjct: 784 FDSIIVILSLMELGLSRMSNLSVLRSFRLLRVF---KLAKSWPTLNTLIKIIGNSVGALG 840
Query: 2091 HMAFVVSVYFFVYMAFGYLVFGQH-------------EWNYSNLIHSTQTVFSYCVSAFQ 2137
++ V+++ F++ G +FG++ W+ + H+ +F +
Sbjct: 841 NLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWI 900
Query: 2138 NTEFSNNRILG-VLFLSSFMLVMI---CVLINLFQAVILSAY 2175
T + + G L L F+LVM+ V++NLF A++LS++
Sbjct: 901 ETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSF 942
>gi|150417967 voltage-gated sodium channel type V alpha isoform c
[Homo sapiens]
Length = 2016
Score = 48.1 bits (113), Expect = 1e-04
Identities = 56/273 (20%), Positives = 111/273 (40%), Gaps = 64/273 (23%)
Query: 1954 LADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQE--RASYVRSVYNLLNFALKCIFTV 2011
+ + D ++ +I + I + F+A E CI+ R Y + +N+ +F + + V
Sbjct: 1546 MVETDDQSPEKINILAKINLLFVAIFTGE-CIVKLAALRHYYFTNSWNIFDFVVVILSIV 1604
Query: 2012 LIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRF 2071
VL + II+ Y +P F ++++ I+R+I G T+L L S
Sbjct: 1605 GTVL--------SDIIQKYFFSPTLFRVIR-LARIGRILRLIRGAKGIRTLLFALMMS-- 1653
Query: 2072 FYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW--------NYSNLIH 2123
LP + ++ ++ + F+Y FG F +W N+ +
Sbjct: 1654 --------------LPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFAN 1699
Query: 2124 STQTVFS--------------------YCVSAFQNTEFSN----NRILGVLFLSSFMLVM 2159
S +F YC N+ S + +G+LF ++++++
Sbjct: 1700 SMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIIS 1759
Query: 2160 ICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
+++N++ A+IL A EE +P+ E+ D
Sbjct: 1760 FLIVVNMYIAIILENFSVATEESTEPLSEDDFD 1792
Score = 37.0 bits (84), Expect = 0.22
Identities = 34/162 (20%), Positives = 75/162 (46%), Gaps = 29/162 (17%)
Query: 2040 FHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQ---------RAIQAALPGIC 2090
F ++ + +M + L + L++L++ R R F +LA+ + I ++ +
Sbjct: 784 FDSIIVILSLMELGLSRMSNLSVLRSFRLLRVF---KLAKSWPTLNTLIKIIGNSVGALG 840
Query: 2091 HMAFVVSVYFFVYMAFGYLVFGQH-------------EWNYSNLIHSTQTVFSYCVSAFQ 2137
++ V+++ F++ G +FG++ W+ + H+ +F +
Sbjct: 841 NLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWI 900
Query: 2138 NTEFSNNRILG-VLFLSSFMLVMI---CVLINLFQAVILSAY 2175
T + + G L L F+LVM+ V++NLF A++LS++
Sbjct: 901 ETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSF 942
>gi|239748090 PREDICTED: similar to sodium channel, voltage-gated,
type V, alpha (long QT syndrome 3) [Homo sapiens]
Length = 1637
Score = 48.1 bits (113), Expect = 1e-04
Identities = 56/273 (20%), Positives = 111/273 (40%), Gaps = 64/273 (23%)
Query: 1954 LADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQE--RASYVRSVYNLLNFALKCIFTV 2011
+ + D ++ +I + I + F+A E CI+ R Y + +N+ +F + + V
Sbjct: 1155 MVETDDQSPEKINILAKINLLFVAIFTGE-CIVKLAALRHYYFTNSWNIFDFVVVILSIV 1213
Query: 2012 LIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRF 2071
VL + II+ Y +P F ++++ I+R+I G T+L L S
Sbjct: 1214 GTVL--------SDIIQKYFFSPTLFRVIR-LARIGRILRLIRGAKGIRTLLFALMMS-- 1262
Query: 2072 FYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW--------NYSNLIH 2123
LP + ++ ++ + F+Y FG F +W N+ +
Sbjct: 1263 --------------LPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFAN 1308
Query: 2124 STQTVFS--------------------YCVSAFQNTEFSN----NRILGVLFLSSFMLVM 2159
S +F YC N+ S + +G+LF ++++++
Sbjct: 1309 SMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIIS 1368
Query: 2160 ICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
+++N++ A+IL A EE +P+ E+ D
Sbjct: 1369 FLIVVNMYIAIILENFSVATEESTEPLSEDDFD 1401
>gi|54792073 mucolipin 2 [Homo sapiens]
Length = 566
Score = 45.1 bits (105), Expect = 8e-04
Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 7/136 (5%)
Query: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111
I LG L + +RY +F + +QA+LP + + + Y G++V
Sbjct: 380 IFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVL 439
Query: 2112 GQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNR-------ILGVLFLSSFMLVMICVLI 2164
G + + NL + +FS F+ + + L+L SF+ + I +++
Sbjct: 440 GPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMIL 499
Query: 2165 NLFQAVILSAYEEMKQ 2180
+LF A+I +Y+ +K+
Sbjct: 500 SLFIALITDSYDTIKK 515
>gi|237512980 voltage-gated sodium channel type V alpha isoform e
[Homo sapiens]
Length = 1983
Score = 42.7 bits (99), Expect = 0.004
Identities = 33/161 (20%), Positives = 67/161 (41%), Gaps = 36/161 (22%)
Query: 2064 KTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW------- 2116
+ LR R +R A+ +LP + ++ ++ + F+Y FG F +W
Sbjct: 1599 RILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDM 1658
Query: 2117 -NYSNLIHSTQTVFS--------------------YCVSAFQNTEFSN----NRILGVLF 2151
N+ +S +F YC N+ S + +G+LF
Sbjct: 1659 FNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILF 1718
Query: 2152 LSSFMLVMICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
++++++ +++N++ A+IL A EE +P+ E+ D
Sbjct: 1719 FTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFD 1759
Score = 37.0 bits (84), Expect = 0.22
Identities = 34/162 (20%), Positives = 75/162 (46%), Gaps = 29/162 (17%)
Query: 2040 FHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQ---------RAIQAALPGIC 2090
F ++ + +M + L + L++L++ R R F +LA+ + I ++ +
Sbjct: 784 FDSIIVILSLMELGLSRMSNLSVLRSFRLLRVF---KLAKSWPTLNTLIKIIGNSVGALG 840
Query: 2091 HMAFVVSVYFFVYMAFGYLVFGQH-------------EWNYSNLIHSTQTVFSYCVSAFQ 2137
++ V+++ F++ G +FG++ W+ + H+ +F +
Sbjct: 841 NLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWI 900
Query: 2138 NTEFSNNRILG-VLFLSSFMLVMI---CVLINLFQAVILSAY 2175
T + + G L L F+LVM+ V++NLF A++LS++
Sbjct: 901 ETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSF 942
>gi|110835710 sodium channel, voltage-gated, type X, alpha [Homo
sapiens]
Length = 1956
Score = 40.4 bits (93), Expect = 0.020
Identities = 32/161 (19%), Positives = 66/161 (40%), Gaps = 36/161 (22%)
Query: 2064 KTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEW------- 2116
+ LR R +R A+ +LP + ++ ++ + F+Y FG F W
Sbjct: 1582 RILRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSSFPHVRWEAGIDDM 1641
Query: 2117 -NYSNLIHSTQTVFS--------------------YCVSAFQNTEFSN----NRILGVLF 2151
N+ +S +F YC N+ + + +G++F
Sbjct: 1642 FNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPNLPNSNGTRGDCGSPAVGIIF 1701
Query: 2152 LSSFMLVMICVLINLFQAVILS----AYEEMKQPVYEEPSD 2188
++++++ +++N++ AVIL A EE +P+ E+ D
Sbjct: 1702 FTTYIIISFLIMVNMYIAVILENFNVATEESTEPLSEDDFD 1742
Score = 31.6 bits (70), Expect = 9.2
Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 19/93 (20%)
Query: 2106 FGYLVFGQHEWNYSNLIH-STQTVFSYCVSAFQNTEFSNNRI-----LGVLFLSSFMLVM 2159
F Y F W + +L TQ + +Q T ++ +I + V+FL SF LV
Sbjct: 334 FNYTSFDSFAWAFLSLFRLMTQDSWE---RLYQQTLRTSGKIYMIFFVLVIFLGSFYLV- 389
Query: 2160 ICVLINLFQAVILSAYEEMKQPVYEEPSDEVEA 2192
NL AV+ AYEE Q +DE+EA
Sbjct: 390 -----NLILAVVTMAYEEQNQAT----TDEIEA 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,239,148
Number of Sequences: 37866
Number of extensions: 3890952
Number of successful extensions: 15973
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 15503
Number of HSP's gapped (non-prelim): 542
length of query: 2253
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2135
effective length of database: 13,779,330
effective search space: 29418869550
effective search space used: 29418869550
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.