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Search of human proteins with 51477718
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51477718 TATA box binding protein-associated factor, RNA
polymerase II, Q [Homo sapiens]
(462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51477718 TATA box binding protein-associated factor, RNA poly... 912 0.0
gi|14717407 TATA box-binding protein-associated factor 2F [Homo ... 394 e-109
gi|18093112 ABT1-associated protein [Homo sapiens] 59 7e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 58 2e-08
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 56 8e-08
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 56 8e-08
gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens] 55 1e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 55 2e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 55 2e-07
gi|115529449 upstream binding transcription factor, RNA polymera... 54 2e-07
gi|115529451 upstream binding transcription factor, RNA polymera... 54 2e-07
gi|7657671 upstream binding transcription factor, RNA polymerase... 54 2e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 54 3e-07
gi|42740903 MTERF domain containing 2 [Homo sapiens] 54 4e-07
gi|55956788 nucleolin [Homo sapiens] 54 4e-07
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens] 54 4e-07
gi|21361639 DIPB protein [Homo sapiens] 53 5e-07
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 53 5e-07
gi|221219020 NYD-SP11 protein [Homo sapiens] 53 7e-07
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens] 53 7e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 53 7e-07
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 53 7e-07
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 52 1e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 52 1e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 51 3e-06
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 51 3e-06
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 3e-06
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 3e-06
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 3e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 3e-06
>gi|51477718 TATA box binding protein-associated factor, RNA
polymerase II, Q [Homo sapiens]
Length = 462
Score = 912 bits (2357), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 1 MECPEGQLPISSENDSTPTVSTSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPAD 60
MECPEGQLPISSENDSTPTVSTSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPAD
Sbjct: 1 MECPEGQLPISSENDSTPTVSTSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPAD 60
Query: 61 EDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARS 120
EDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARS
Sbjct: 61 EDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARS 120
Query: 121 QSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQM 180
QSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQM
Sbjct: 121 QSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQM 180
Query: 181 LVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK 240
LVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK
Sbjct: 181 LVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK 240
Query: 241 VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF 300
VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF
Sbjct: 241 VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF 300
Query: 301 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE 360
LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE
Sbjct: 301 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE 360
Query: 361 DCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIM 420
DCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIM
Sbjct: 361 DCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIM 420
Query: 421 KVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK 462
KVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
Sbjct: 421 KVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK 462
>gi|14717407 TATA box-binding protein-associated factor 2F [Homo
sapiens]
Length = 349
Score = 394 bits (1011), Expect = e-109
Identities = 212/377 (56%), Positives = 276/377 (73%), Gaps = 29/377 (7%)
Query: 87 MSESQDEVPDEVENQFILRLPLEHACTVRNLARSQSVKMKDKLKIDLLPDGRHAVVEVED 146
MS+S+D+ P E+E+QFILRLP E+A TVR +S V +KD+L I+L PDGRH +V V+
Sbjct: 1 MSKSKDDAPHELESQFILRLPPEYASTVRRAVQSGHVNLKDRLTIELHPDGRHGIVRVDR 60
Query: 147 VPLAAKLVDLPCVIESLRTLDKKTFYKTADISQMLVCTADGDIHLSPEEPAASTDPNIVR 206
VPLA+KLVDLPCV+ESL+T+DKKTFYKTADI QMLV T DGD++ EEP ASTDP +
Sbjct: 61 VPLASKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVASTDPKASK 120
Query: 207 KKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK 266
KK++ +E+K +W HGIT PLKNVRK+RFRKT KK +YIESPDVE EVK
Sbjct: 121 KKDKDKEKKFIWNHGITLPLKNVRKRRFRKTAKK-------------KYIESPDVEKEVK 167
Query: 267 RLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFS 326
RLL +DAEAVSTRWE+IAED TKE E+QG + S GMS H+QGH S E+D LRE+F+
Sbjct: 168 RLLSTDAEAVSTRWEIIAEDETKEAENQGL---DISSPGMSGHRQGHDSLEHDELREIFN 224
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESG-QYRANE 385
D S++ EDEDE + +D+E+ +EE LERQLQ + ES Q++ NE
Sbjct: 225 DLSSSS------------EDEDETQHQDEEDINIIDTEEDLERQLQDKLNESDEQHQENE 272
Query: 386 GTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQEKQK 445
GT+ +VM IQKQI+ + KL + Q++A+RQ+DLIMKVENL LKN FQ+VL++L+ +E ++
Sbjct: 273 GTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDRE 332
Query: 446 NEKLISLQEQLQRFLKK 462
E+L SLQE+L+ L+K
Sbjct: 333 KEQLSSLQEELESLLEK 349
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 59.3 bits (142), Expect = 7e-09
Identities = 43/148 (29%), Positives = 76/148 (51%), Gaps = 12/148 (8%)
Query: 227 KNVRKKRF---RKTQKKVPDVKEMEKSSFTEYIESPDVE-NEVKRLLRSDAEAVSTRWEV 282
KN ++K+ T + + + S +E ++SP +E ++ +R ++S + + TR
Sbjct: 164 KNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSD 223
Query: 283 IAEDGTK-EIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDE 341
E+ T E+ + ++ S S+ + E+ S R++ DDD EDDE
Sbjct: 224 GYENSTDGEMCDKDALEE-------DSESVSEIGSDEESENEITSVGRASGDDDGSEDDE 276
Query: 342 DEDEDEDEDEDEDKEEEEEDCSEEYLER 369
+EDEDE+EDEDED E++++ S L R
Sbjct: 277 EEDEDEEEDEDEDSEDDDKSDSGPDLAR 304
Score = 36.6 bits (83), Expect = 0.049
Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 235 RKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQ 294
+K K+ + EK + ++ +E E +R L S + + +E++S
Sbjct: 155 KKDSKEFTQKNKKEKKNIVQHTTDSSLE-EKQRTLDSGTSEIVKSPRIECSKTRREMQSV 213
Query: 295 GSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDE-----DEDEDE 349
+ S G + G + D L E DS S ++ DE+ E+E D+
Sbjct: 214 VQLIMTRDSDGYENSTDGEMCDK-DALEE---DSESVSEIGSDEESENEITSVGRASGDD 269
Query: 350 DEDEDKEEEEEDCSEEYLERQLQAEFIESG 379
D ED EEE+ED E+ E + +SG
Sbjct: 270 DGSEDDEEEDEDEEEDEDEDSEDDDKSDSG 299
Score = 33.5 bits (75), Expect = 0.42
Identities = 52/253 (20%), Positives = 99/253 (39%), Gaps = 32/253 (12%)
Query: 204 IVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVEN 263
+V+ K G+++ W+ + K KKR ++ QK + + E+ + P
Sbjct: 618 MVKNKLEGKDKLTPWEQFLE---KKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAE 674
Query: 264 EVKRLLRSDAEAVSTRWEVIAEDGTK-----EIESQGSIPGFLISSGMSSHKQGHTSSEY 318
EVK++ ++ + A+DGT EIE Q + L+ M + Y
Sbjct: 675 EVKQI------GINKKSVKSAKDGTSPEEEIEIERQKAEMALLM---MDEDEDSKKHFNY 725
Query: 319 DMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEE------EEDCSEEYLERQLQ 372
+ + E + S+ + + ED+ E D + D S+ ++
Sbjct: 726 NKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKA 785
Query: 373 AEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQ 432
E I + R E E+ + I+KKE ++ K + L M ++++ K
Sbjct: 786 MEKILEEKARQRERKE---QELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKT--- 839
Query: 433 SVLEQLELQEKQK 445
EQ + ++KQK
Sbjct: 840 ---EQFQARKKQK 849
Score = 31.6 bits (70), Expect = 1.6
Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 22/148 (14%)
Query: 236 KTQKKVPDVKEMEKSSFTE-YIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQ 294
KT++++ V ++ + ++ Y S D E K L D+E+VS E G+ E ES+
Sbjct: 205 KTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVS-------EIGSDE-ESE 256
Query: 295 GSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDED--------ED 346
I +SG + + D + DS +D+D+ D D E
Sbjct: 257 NEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDS-----EDDDKSDSGPDLARGKGNIET 311
Query: 347 EDEDEDEDKEEEEEDCSEEYLERQLQAE 374
EDED+ + E+ E+ R+L +
Sbjct: 312 SSEDEDDTADLFPEESGFEHAWRELDKD 339
Score = 29.6 bits (65), Expect = 6.0
Identities = 91/453 (20%), Positives = 172/453 (37%), Gaps = 66/453 (14%)
Query: 21 STSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPADEDTQTDADSSAQAAAQAPEN 80
S SE+ S +E + + + S D ++ + DE+ D DS + + +
Sbjct: 245 SVSEIGSDEESENEI---TSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPD 301
Query: 81 FQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARSQSVKMKDKLKIDLLPDGRHA 140
GK E+ E D+ + F EHA + KD + D + R A
Sbjct: 302 LARGKGNIETSSEDEDDTADLFPEESGFEHAWRELD---------KDAPRADEITR-RLA 351
Query: 141 VVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQMLVCTADGDIHLSPEEPAAST 200
V ++ L AK DL + S + F S + + G + E+
Sbjct: 352 VCNMDWDRLKAK--DLLALFNSFKPKGGVIF------SVKIYPSEFGKERMKEEQVQGPV 403
Query: 201 D----PNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYI 256
+ P +K+ EK L++ + KR K V D E +S Y
Sbjct: 404 ELLSIPEDAPEKDWTSREK----------LRDYQFKRL-KYYYAVVDCDSPETASKI-YE 451
Query: 257 ESPDVENEVKRLLRSDAEAVSTRW---EVIAEDGTKEIESQGSI----PGFLISSGMSSH 309
+ +E E S + R+ ++ +D K++ S+ ++ P + S+ M +
Sbjct: 452 DCDGLEFE------SSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTS 505
Query: 310 KQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLER 369
T E D R + + ++ D D + EDE+E +EE + D
Sbjct: 506 TVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDG------ 559
Query: 370 QLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKN 429
E G+ + ++ + ++QI K + L IQ K ++ K+ M++E +
Sbjct: 560 ---VNVEEDGKTKKSQ------KDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPG 610
Query: 430 HFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK 462
+S E++ + + +KL ++ L++ +K
Sbjct: 611 LKESA-EEMVKNKLEGKDKLTPWEQFLEKKKEK 642
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 57.8 bits (138), Expect = 2e-08
Identities = 25/81 (30%), Positives = 57/81 (70%), Gaps = 2/81 (2%)
Query: 330 SNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSS 389
+++D++E+E++E+E+E+E+E+E+E+ EEEE+ EEY E + + E ++ EG
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG--E 941
Query: 390 IVMEIQKQIEKKEKKLHKIQN 410
+ E +++ E++E++L ++++
Sbjct: 942 LEEEEEEEDEEEEEELEEVED 962
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/57 (38%), Positives = 33/57 (57%)
Query: 323 EMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESG 379
E F + ++ E+E +E+E E E+E+E+ED+EEEEE E LE +E G
Sbjct: 919 EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/63 (33%), Positives = 37/63 (58%)
Query: 317 EYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFI 376
E D E + +++E+E++ +E+ +E+E E E++EEEE++ EE LE EF
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG 966
Query: 377 ESG 379
+G
Sbjct: 967 TAG 969
Score = 38.9 bits (89), Expect = 0.010
Identities = 21/74 (28%), Positives = 40/74 (54%)
Query: 301 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE 360
+I+ S ++ E + E + +++EDE++ E+E+E+E+E E++ EEEE
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939
Query: 361 DCSEEYLERQLQAE 374
EE E + + E
Sbjct: 940 GELEEEEEEEDEEE 953
Score = 37.4 bits (85), Expect = 0.029
Identities = 22/79 (27%), Positives = 46/79 (58%), Gaps = 3/79 (3%)
Query: 348 DEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHK 407
DE+E+E++EEEEE+ EE E + E + +Y E E +++ E++E +L +
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE--EEFEEEFEEEEGELEE 944
Query: 408 IQNKA-QRQKDLIMKVENL 425
+ + + +++ + +VE+L
Sbjct: 945 EEEEEDEEEEEELEEVEDL 963
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 55.8 bits (133), Expect = 8e-08
Identities = 22/67 (32%), Positives = 44/67 (65%)
Query: 307 SSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEY 366
+ +++G S + + D + DD++D+DD+D+D+D+D+++DED+E+ EE+ + Y
Sbjct: 235 TDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQKRY 294
Query: 367 LERQLQA 373
RQ +A
Sbjct: 295 YLRQRKA 301
Score = 46.2 bits (108), Expect = 6e-05
Identities = 42/186 (22%), Positives = 85/186 (45%), Gaps = 23/186 (12%)
Query: 206 RKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVP----DVKEMEKSSFTEYIESPDV 261
+KKE RE+K + P +++R + ++ + + DV+ +
Sbjct: 116 KKKEEHREDKVI------PVTRSLRARNIVQSTEHLHEDNGDVEVRRSCRIRSRYSGVNQ 169
Query: 262 ENEVKRLLRSDAEAVSTRWEVIAE---DGTKEIESQGSIPGFLISSGMSSHKQG------ 312
+L+ + AEAV + + + + +E+E G + S ++ + +G
Sbjct: 170 SMLFDKLITNTAEAVLQKMDDMKKMRRQRMRELEDLG-VFNETEESNLNMYTRGKQKDIQ 228
Query: 313 HTSSEYDMLREMFSDSRSNNDDDEDEDD---EDEDEDEDEDEDEDKEEEEEDCSEEYLER 369
T E +E +S +D E EDD ED+++D+D+D+D+D +++E+D EE E
Sbjct: 229 RTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEE 288
Query: 370 QLQAEF 375
+ Q +
Sbjct: 289 ENQKRY 294
Score = 42.4 bits (98), Expect = 9e-04
Identities = 17/77 (22%), Positives = 45/77 (58%)
Query: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGT 387
S ++++ ED++ ED+ EDED+++D+D +++++D +E E + E +Y +
Sbjct: 241 SVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQKRYYLRQRK 300
Query: 388 SSIVMEIQKQIEKKEKK 404
+++ + + + ++K
Sbjct: 301 ATVYYQAPLEKPRHQRK 317
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 55.8 bits (133), Expect = 8e-08
Identities = 53/210 (25%), Positives = 97/210 (46%), Gaps = 24/210 (11%)
Query: 207 KKERGREEKCVWKHGITP-PLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEV 265
++ERG + C+++ + K R+++ R+ QK+ + KE E+ + E + + EV
Sbjct: 151 RRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRA-EERRKEREARREV 209
Query: 266 K---RLLRSDA--EAVSTRWEVIAE----------DGTKEIESQGSIPGFLISSGMS-SH 309
R +R D + ++ W DG K ++ + L+S S
Sbjct: 210 SAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD 269
Query: 310 KQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC---SEEY 366
+ TSS E S S +++E+E++E +E E+E+E++EEEEE+ SEE
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329
Query: 367 LER---QLQAEFIESGQYRANEGTSSIVME 393
E+ ++ E + + R NE +V E
Sbjct: 330 SEQSAEEVSEEEMSEDEERENENHLLVVPE 359
Score = 32.3 bits (72), Expect = 0.93
Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Query: 345 EDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIE--SGQYRANEGTSSIVMEIQKQIEKKE 402
E E E E + EE+D + ERQ + E S + R N+G + + +Q+E+K
Sbjct: 115 EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGV-CLFRDRLEQLERKR 173
Query: 403 KKLHKIQNKAQRQKD 417
++ K++ + + Q++
Sbjct: 174 ERERKMREQQKEQRE 188
>gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 486
Score = 55.1 bits (131), Expect = 1e-07
Identities = 39/151 (25%), Positives = 73/151 (48%), Gaps = 9/151 (5%)
Query: 225 PLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIES--PDVENEVKRLLRSD-AEAVSTRWE 281
P K KK+F K P+ + S+F Y P ++ E L D A+ + W
Sbjct: 216 PPKGETKKKF-----KDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWN 270
Query: 282 VIAEDGTKEIESQGSIPGFLISSGMSSHK-QGHTSSEYDMLREMFSDSRSNNDDDEDEDD 340
A D + E + + +++++ +G + + + + + +++ +ED+
Sbjct: 271 NTAADDKQPYEKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDE 330
Query: 341 EDEDEDEDEDEDEDKEEEEEDCSEEYLERQL 371
EDE+E++DEDEDE+ +E+EED +E QL
Sbjct: 331 EDEEEEKDEDEDEEDDEDEEDGDDEQSHWQL 361
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 8/97 (8%)
Query: 270 RSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSR 329
R+ + S++ EV +E+ + E+ SSG S + +T +E + + E +
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETG--------SSGSSDEQGNNTENEEEGVEEDVEEDE 213
Query: 330 SNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEY 366
+D E++++ DED +E+E+E+E++EEEEE+ EEY
Sbjct: 214 EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY 250
Score = 48.5 bits (114), Expect = 1e-05
Identities = 24/74 (32%), Positives = 41/74 (55%)
Query: 307 SSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEY 366
S H+ G + S + ++ +D E++++ +ED +EDE+ DED EEEEE+ EE
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
Query: 367 LERQLQAEFIESGQ 380
E + + E E +
Sbjct: 241 EEEEEEEEEYEQDE 254
Score = 38.5 bits (88), Expect = 0.013
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 303 SSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC 362
S S K+ S EY E S S + D++ + E+E+E +ED +ED+E EE+
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGS---SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220
Query: 363 SEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKA 412
+E ++ + E E + E E ++ +K+E + +++A
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEA 270
Score = 37.7 bits (86), Expect = 0.022
Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 6/90 (6%)
Query: 315 SSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAE 374
+ E + + E + +++E+E++E+E+E E ++ D+ +E + D E + ++
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
Query: 375 FIESGQYRANEGTSSIVMEIQKQIEKKEKK 404
G R+ GT +KKE+K
Sbjct: 279 SFTDGSVRSGSGTDG------SDEKKKERK 302
Score = 29.6 bits (65), Expect = 6.0
Identities = 16/67 (23%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Query: 36 DRGSETTYESSA---DIAGDEGTQIPADEDTQTDADSSAQAAAQAPENFQEGKDMSESQD 92
++G+ T E D+ DE + A+ED + D D + + E +E ++ E +
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Query: 93 EVPDEVE 99
+ D+ E
Sbjct: 253 DERDQKE 259
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 8/97 (8%)
Query: 270 RSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSR 329
R+ + S++ EV +E+ + E+ SSG S + +T +E + + E +
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETG--------SSGSSDEQGNNTENEEEGVEEDVEEDE 213
Query: 330 SNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEY 366
+D E++++ DED +E+E+E+E++EEEEE+ EEY
Sbjct: 214 EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY 250
Score = 48.5 bits (114), Expect = 1e-05
Identities = 24/74 (32%), Positives = 41/74 (55%)
Query: 307 SSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEY 366
S H+ G + S + ++ +D E++++ +ED +EDE+ DED EEEEE+ EE
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
Query: 367 LERQLQAEFIESGQ 380
E + + E E +
Sbjct: 241 EEEEEEEEEYEQDE 254
Score = 38.5 bits (88), Expect = 0.013
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 303 SSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC 362
S S K+ S EY E S S + D++ + E+E+E +ED +ED+E EE+
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGS---SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220
Query: 363 SEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKA 412
+E ++ + E E + E E ++ +K+E + +++A
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEA 270
Score = 37.7 bits (86), Expect = 0.022
Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 6/90 (6%)
Query: 315 SSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAE 374
+ E + + E + +++E+E++E+E+E E ++ D+ +E + D E + ++
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
Query: 375 FIESGQYRANEGTSSIVMEIQKQIEKKEKK 404
G R+ GT +KKE+K
Sbjct: 279 SFTDGSVRSGSGTDG------SDEKKKERK 302
Score = 29.6 bits (65), Expect = 6.0
Identities = 16/67 (23%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Query: 36 DRGSETTYESSA---DIAGDEGTQIPADEDTQTDADSSAQAAAQAPENFQEGKDMSESQD 92
++G+ T E D+ DE + A+ED + D D + + E +E ++ E +
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Query: 93 EVPDEVE 99
+ D+ E
Sbjct: 253 DERDQKE 259
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 54.3 bits (129), Expect = 2e-07
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 24/183 (13%)
Query: 194 EEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK--------VPDVK 245
+E ++ + N + KER E W+ I+ K KK + QK+ V +
Sbjct: 543 QELLSNGELNHLPLKERMVEIGSRWQR-ISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLS 601
Query: 246 EMEKSSFTEYIESP-----DVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF 300
+++++ EYI + + + R+ ++ S E ED E E +
Sbjct: 602 PQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD- 660
Query: 301 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE 360
+G SS G +S E S+ S + D+ +EDDEDED+DED+DEDED E E
Sbjct: 661 --ENGDSSEDGGDSS-------ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGS 711
Query: 361 DCS 363
S
Sbjct: 712 SSS 714
Score = 52.8 bits (125), Expect = 7e-07
Identities = 24/43 (55%), Positives = 30/43 (69%)
Query: 326 SDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLE 368
S S S DD+EDEDDEDEDE+E++DE+ D E+ D SE E
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678
Score = 47.8 bits (112), Expect = 2e-05
Identities = 18/37 (48%), Positives = 32/37 (86%)
Query: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSE 364
S S+++D+ ++ DE+E++DEDED+DED +E+E++ SE
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Score = 40.8 bits (94), Expect = 0.003
Identities = 13/39 (33%), Positives = 29/39 (74%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
DS ++ +DE ED ++ +ED+++++D++ ++E+ED E
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Score = 38.5 bits (88), Expect = 0.013
Identities = 14/38 (36%), Positives = 27/38 (71%)
Query: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
SR+ + +++DE++++DEDEDE++E++E S E
Sbjct: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE 667
Score = 37.4 bits (85), Expect = 0.029
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 9/88 (10%)
Query: 311 QGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDED---------EDEDEDEDEDKEEEEED 361
Q + SE D + + ++D++ D ED EDE ED DE++E++E++
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 362 CSEEYLERQLQAEFIESGQYRANEGTSS 389
+E + E S ++ G SS
Sbjct: 695 DDDEDDDEDEDNESEGSSSSSSSSGDSS 722
Score = 29.3 bits (64), Expect = 7.9
Identities = 34/165 (20%), Positives = 68/165 (41%), Gaps = 15/165 (9%)
Query: 208 KERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKR 267
+++ R E+ + + P N KK + + K P + +K F++ + S N +
Sbjct: 499 EDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK--FSQELLSNGELNHLP- 555
Query: 268 LLRSDAEAVSTRWEVIAEDG-------TKEIESQGSIPGFLISSGMSSHKQGHTSSEYDM 320
L+ + +RW+ I++ +E + Q + L +S +
Sbjct: 556 -LKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISN 614
Query: 321 LREMFSDSRSNNDDDEDEDDEDEDEDEDEDED----EDKEEEEED 361
R+ + R N + + E E++DE+ ED++EEEED
Sbjct: 615 KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 659
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 54.3 bits (129), Expect = 2e-07
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 24/183 (13%)
Query: 194 EEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK--------VPDVK 245
+E ++ + N + KER E W+ I+ K KK + QK+ V +
Sbjct: 543 QELLSNGELNHLPLKERMVEIGSRWQR-ISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLS 601
Query: 246 EMEKSSFTEYIESP-----DVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF 300
+++++ EYI + + + R+ ++ S E ED E E +
Sbjct: 602 PQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD- 660
Query: 301 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE 360
+G SS G +S E S+ S + D+ +EDDEDED+DED+DEDED E E
Sbjct: 661 --ENGDSSEDGGDSS-------ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGS 711
Query: 361 DCS 363
S
Sbjct: 712 SSS 714
Score = 52.8 bits (125), Expect = 7e-07
Identities = 24/43 (55%), Positives = 30/43 (69%)
Query: 326 SDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLE 368
S S S DD+EDEDDEDEDE+E++DE+ D E+ D SE E
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678
Score = 47.8 bits (112), Expect = 2e-05
Identities = 18/37 (48%), Positives = 32/37 (86%)
Query: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSE 364
S S+++D+ ++ DE+E++DEDED+DED +E+E++ SE
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Score = 40.8 bits (94), Expect = 0.003
Identities = 13/39 (33%), Positives = 29/39 (74%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
DS ++ +DE ED ++ +ED+++++D++ ++E+ED E
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Score = 38.5 bits (88), Expect = 0.013
Identities = 14/38 (36%), Positives = 27/38 (71%)
Query: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
SR+ + +++DE++++DEDEDE++E++E S E
Sbjct: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE 667
Score = 37.4 bits (85), Expect = 0.029
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 9/88 (10%)
Query: 311 QGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDED---------EDEDEDEDEDKEEEEED 361
Q + SE D + + ++D++ D ED EDE ED DE++E++E++
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 362 CSEEYLERQLQAEFIESGQYRANEGTSS 389
+E + E S ++ G SS
Sbjct: 695 DDDEDDDEDEDNESEGSSSSSSSSGDSS 722
Score = 29.3 bits (64), Expect = 7.9
Identities = 34/165 (20%), Positives = 68/165 (41%), Gaps = 15/165 (9%)
Query: 208 KERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKR 267
+++ R E+ + + P N KK + + K P + +K F++ + S N +
Sbjct: 499 EDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK--FSQELLSNGELNHLP- 555
Query: 268 LLRSDAEAVSTRWEVIAEDG-------TKEIESQGSIPGFLISSGMSSHKQGHTSSEYDM 320
L+ + +RW+ I++ +E + Q + L +S +
Sbjct: 556 -LKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISN 614
Query: 321 LREMFSDSRSNNDDDEDEDDEDEDEDEDEDED----EDKEEEEED 361
R+ + R N + + E E++DE+ ED++EEEED
Sbjct: 615 KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 659
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 54.3 bits (129), Expect = 2e-07
Identities = 51/183 (27%), Positives = 81/183 (44%), Gaps = 24/183 (13%)
Query: 194 EEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK--------VPDVK 245
+E ++ + N + KER E W+ I+ K KK + QK+ V +
Sbjct: 580 QELLSNGELNHLPLKERMVEIGSRWQR-ISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLS 638
Query: 246 EMEKSSFTEYIESP-----DVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF 300
+++++ EYI + + + R+ ++ S E ED E E +
Sbjct: 639 PQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD- 697
Query: 301 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE 360
+G SS G +S E S+ S + D+ +EDDEDED+DED+DEDED E E
Sbjct: 698 --ENGDSSEDGGDSS-------ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGS 748
Query: 361 DCS 363
S
Sbjct: 749 SSS 751
Score = 52.8 bits (125), Expect = 7e-07
Identities = 24/43 (55%), Positives = 30/43 (69%)
Query: 326 SDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLE 368
S S S DD+EDEDDEDEDE+E++DE+ D E+ D SE E
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 715
Score = 47.8 bits (112), Expect = 2e-05
Identities = 18/37 (48%), Positives = 32/37 (86%)
Query: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSE 364
S S+++D+ ++ DE+E++DEDED+DED +E+E++ SE
Sbjct: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746
Score = 40.8 bits (94), Expect = 0.003
Identities = 13/39 (33%), Positives = 29/39 (74%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
DS ++ +DE ED ++ +ED+++++D++ ++E+ED E
Sbjct: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746
Score = 38.5 bits (88), Expect = 0.013
Identities = 14/38 (36%), Positives = 27/38 (71%)
Query: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
SR+ + +++DE++++DEDEDE++E++E S E
Sbjct: 667 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE 704
Score = 37.4 bits (85), Expect = 0.029
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 9/88 (10%)
Query: 311 QGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDED---------EDEDEDEDEDKEEEEED 361
Q + SE D + + ++D++ D ED EDE ED DE++E++E++
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
Query: 362 CSEEYLERQLQAEFIESGQYRANEGTSS 389
+E + E S ++ G SS
Sbjct: 732 DDDEDDDEDEDNESEGSSSSSSSSGDSS 759
Score = 29.3 bits (64), Expect = 7.9
Identities = 34/165 (20%), Positives = 68/165 (41%), Gaps = 15/165 (9%)
Query: 208 KERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKR 267
+++ R E+ + + P N KK + + K P + +K F++ + S N +
Sbjct: 536 EDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK--FSQELLSNGELNHLP- 592
Query: 268 LLRSDAEAVSTRWEVIAEDG-------TKEIESQGSIPGFLISSGMSSHKQGHTSSEYDM 320
L+ + +RW+ I++ +E + Q + L +S +
Sbjct: 593 -LKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISN 651
Query: 321 LREMFSDSRSNNDDDEDEDDEDEDEDEDEDED----EDKEEEEED 361
R+ + R N + + E E++DE+ ED++EEEED
Sbjct: 652 KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 696
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 53.9 bits (128), Expect = 3e-07
Identities = 32/115 (27%), Positives = 61/115 (53%), Gaps = 17/115 (14%)
Query: 257 ESPDVENEVKRLL-------RSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSH 309
E + E E +RL+ + + E +STR + +++S+ + S
Sbjct: 1000 EEREAEKEAERLMEQASCWEKEEQEILSTRAN--SRQSPAKVQSKNKY--------LHSP 1049
Query: 310 KQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSE 364
+ + E L E+ +S +++EDE++E+E+E+E+EDE+E++EEEEE+ E
Sbjct: 1050 ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 39.7 bits (91), Expect = 0.006
Identities = 34/124 (27%), Positives = 65/124 (52%), Gaps = 10/124 (8%)
Query: 326 SDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE---YLERQ---LQAEFIESG 379
S + S + ED+ + E+E+E+E+E+E++EEEEE EE +E+ +++ E
Sbjct: 1334 SPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEP 1393
Query: 380 QYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIM---KVENLTL-KNHFQSVL 435
+ + S+ + + +++ E+ E+ H + A + D M +VE L + F+ VL
Sbjct: 1394 EISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVL 1453
Query: 436 EQLE 439
E E
Sbjct: 1454 ENQE 1457
Score = 38.5 bits (88), Expect = 0.013
Identities = 45/200 (22%), Positives = 79/200 (39%), Gaps = 44/200 (22%)
Query: 184 TADGDIHLSP---EEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK 240
T++G SP EE T ++ ++E REE C T P +K
Sbjct: 1295 TSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSP-----------GEKP 1343
Query: 241 VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF 300
D+ + E+ E E + E E E E+G +E
Sbjct: 1344 EDDLIKPEEEEEEEEEEEEEEEEE----------------EGEEEEGGGNVEKD------ 1381
Query: 301 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDED--EDEDEDEDEDEDKEEE 358
G S ++ E ++ E +R ++ ++E+E+DE+ +ED D D+++D E
Sbjct: 1382 --PDGAKSQEK----EEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHME 1435
Query: 359 EEDCSEEYLERQLQAEFIES 378
+ +E L R+ E +E+
Sbjct: 1436 SAEVEKEELPRESFKEVLEN 1455
Score = 34.3 bits (77), Expect = 0.24
Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 2/74 (2%)
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKE 402
++ E+E+E+ED+EEEEE+ EE E + + E E + N +S + + + K
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEE--EEEEEEENIQSSPPRLTKPQSVAIKR 1123
Query: 403 KKLHKIQNKAQRQK 416
K+ ++ K R++
Sbjct: 1124 KRPFVLKKKRGRKR 1137
>gi|42740903 MTERF domain containing 2 [Homo sapiens]
Length = 381
Score = 53.5 bits (127), Expect = 4e-07
Identities = 20/35 (57%), Positives = 29/35 (82%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEED 361
D N++DD DEDD+DED+DE ED DED++++EE+
Sbjct: 347 DEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381
Score = 51.2 bits (121), Expect = 2e-06
Identities = 23/57 (40%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Query: 310 KQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDE-DEDEDEDEDEDKEEEEEDCSEE 365
++ +S+ D + D ++++D DEDD DE D+DED+DE ED +E+E+D EE
Sbjct: 325 EESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 53.5 bits (127), Expect = 4e-07
Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 22/115 (19%)
Query: 273 AEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNN 332
A+AV+T + A G + + G + + G K G + + D E DS +
Sbjct: 101 AKAVTTPGKKGATPGKALVATPGKKGAAIPAKGA---KNGKNAKKEDSDEEEDDDSEEDE 157
Query: 333 DDDEDEDD-------------------EDEDEDEDEDEDEDKEEEEEDCSEEYLE 368
+DDEDED+ EDED+++DED+++D ++EE+D EE +E
Sbjct: 158 EDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAME 212
Score = 53.1 bits (126), Expect = 5e-07
Identities = 20/43 (46%), Positives = 33/43 (76%)
Query: 326 SDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLE 368
++ +DDEDEDD+D+++DED+D+++D+EEEEE+ E E
Sbjct: 233 AEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275
Score = 52.4 bits (124), Expect = 9e-07
Identities = 27/77 (35%), Positives = 43/77 (55%), Gaps = 12/77 (15%)
Query: 333 DDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVM 392
D+DE+EDDEDED+D+DED+++D +E++E+ EE E ++ E
Sbjct: 235 DEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVK------------EAPGKRKK 282
Query: 393 EIQKQIEKKEKKLHKIQ 409
E+ KQ E K K++
Sbjct: 283 EMAKQKAAPEAKKQKVE 299
Score = 50.4 bits (119), Expect = 3e-06
Identities = 17/40 (42%), Positives = 32/40 (80%)
Query: 322 REMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEED 361
+ + D DD++++DD+DED+++D+DED+++EEEEE+
Sbjct: 230 KNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEE 269
Score = 49.3 bits (116), Expect = 7e-06
Identities = 19/40 (47%), Positives = 32/40 (80%)
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQ 370
N +DEDE+++DEDED+D+DED++ +++E+D EE E +
Sbjct: 231 NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270
Score = 45.1 bits (105), Expect = 1e-04
Identities = 17/61 (27%), Positives = 38/61 (62%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEG 386
D +DDD+++D++D+DED++E+E+E++EE ++ + + + + + + EG
Sbjct: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG 300
Query: 387 T 387
T
Sbjct: 301 T 301
Score = 40.8 bits (94), Expect = 0.003
Identities = 18/65 (27%), Positives = 38/65 (58%)
Query: 310 KQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLER 369
K + + + D + + +++DDED+DDED++E+E+E+E+E +E +E ++
Sbjct: 228 KAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287
Query: 370 QLQAE 374
+ E
Sbjct: 288 KAAPE 292
Score = 40.8 bits (94), Expect = 0.003
Identities = 16/63 (25%), Positives = 39/63 (61%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEG 386
D ++D+D+++DD+++DE+E+E+E+E+ +E ++ + +Q A + + E
Sbjct: 244 DEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEP 303
Query: 387 TSS 389
T++
Sbjct: 304 TTA 306
Score = 29.3 bits (64), Expect = 7.9
Identities = 13/30 (43%), Positives = 22/30 (73%), Gaps = 1/30 (3%)
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQ 372
ED DE+ED+D + E+EE+D E+ E +++
Sbjct: 143 EDSDEEEDDDSE-EDEEDDEDEDEDEDEIE 171
>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 488
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/153 (26%), Positives = 75/153 (49%), Gaps = 11/153 (7%)
Query: 225 PLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIES--PDVENEVKRLLRSD-AEAVSTRWE 281
P K KK+F K P+ + S+F Y P ++ E L D A+ + W
Sbjct: 216 PPKGETKKKF-----KDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWN 270
Query: 282 VIAEDGTKEIESQGSIPGFLISSGMSSH--KQGHTSSEYDMLREMFSDSRSNNDD-DEDE 338
A D + E + + ++++ K H ++ +++ S + ++ +EDE
Sbjct: 271 NTAADDKQPYEKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDE 330
Query: 339 DDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQL 371
+DE+E++DE+++++ED E+EEED +E QL
Sbjct: 331 EDEEEEKDEEDEDEEDDEDEEEDGDDEQSHWQL 363
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 53.1 bits (126), Expect = 5e-07
Identities = 30/89 (33%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 322 REMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQY 381
RE+ S++ ++ +E+ + E+E E E+E EDE EE EED SEE +E + ++E E Q
Sbjct: 89 REIESEAGEESESEEESESEEESETEEESEDESDEESEED-SEEEMEDEQESEAEEDNQE 147
Query: 382 RAN---EGTSSIVMEIQKQIEKKEKKLHK 407
EG + E +IE + +++ K
Sbjct: 148 EGESEAEGETEAESEFDPEIEMEAERVAK 176
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 12/105 (11%)
Query: 271 SDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRS 330
+D E + + +EIES+ +G S + + SE + E S+ S
Sbjct: 71 ADGEGAGKEEAEVKVEQEREIESE---------AGEESESEEESESEEESETEEESEDES 121
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEF 375
+ + +ED ++E EDE E E E++++EE E SE E + ++EF
Sbjct: 122 DEESEEDSEEEMEDEQESEAEEDNQEEGE---SEAEGETEAESEF 163
Score = 42.7 bits (99), Expect = 7e-04
Identities = 25/81 (30%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Query: 323 EMFSDSRSNNDDDEDEDDEDEDE-DEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQY 381
E S+ S ++++ + ++E EDE DE+ +ED ++E E+E SE + Q + E G+
Sbjct: 98 ESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGET 157
Query: 382 RA-NEGTSSIVMEIQKQIEKK 401
A +E I ME ++ ++K
Sbjct: 158 EAESEFDPEIEMEAERVAKRK 178
Score = 33.5 bits (75), Expect = 0.42
Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 5/91 (5%)
Query: 23 SEVTSQQEPQIPVDRG----SETTYESSADIAGDEGTQIPADEDTQTDADSSAQAAAQAP 78
+EV +QE +I + G SE ES + +E ++ +DE+++ D++ + Q
Sbjct: 81 AEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME-DEQES 139
Query: 79 ENFQEGKDMSESQDEVPDEVENQFILRLPLE 109
E ++ ++ ES+ E E E++F + +E
Sbjct: 140 EAEEDNQEEGESEAEGETEAESEFDPEIEME 170
Score = 29.3 bits (64), Expect = 7.9
Identities = 17/77 (22%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 11 SSENDSTPTVSTSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPADEDTQTDADSS 70
+ E + S SE S+ E + + E+ +S ++ ++ ++ A+ED Q + +S
Sbjct: 95 AGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESE--AEEDNQEEGESE 152
Query: 71 AQAAAQAPENFQEGKDM 87
A+ +A F +M
Sbjct: 153 AEGETEAESEFDPEIEM 169
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 53.1 bits (126), Expect = 5e-07
Identities = 37/121 (30%), Positives = 63/121 (52%), Gaps = 7/121 (5%)
Query: 310 KQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDK---EEEEEDCSEEY 366
K+ EYD +E+ ++ +++E ED+E+E EDE+E+E E+ EE EE+ EE
Sbjct: 282 KKNDDEEEYD--QEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEE 339
Query: 367 LERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLT 426
LE + E +E + R E + M + +E +EK+ + I + +I KV +
Sbjct: 340 LEE--EEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFISCTFLNPEQIIPKVPQES 397
Query: 427 L 427
L
Sbjct: 398 L 398
Score = 50.4 bits (119), Expect = 3e-06
Identities = 24/80 (30%), Positives = 44/80 (55%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEG 386
+ NDD+E+ D E D E +E+E+ E+EEE+ +E E +AE++E G+ E
Sbjct: 279 EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE 338
Query: 387 TSSIVMEIQKQIEKKEKKLH 406
E+ ++ E++ ++ H
Sbjct: 339 ELEEEEEVLEENEQRGEEFH 358
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/166 (28%), Positives = 76/166 (45%), Gaps = 30/166 (18%)
Query: 308 SHKQGHTSSEYDMLREMFS--DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
S + SE EM S D + E++E+ +E+E+ +E+E +EEEEE EE
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273
Query: 366 Y-LERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQ--RQKDLIMKV 422
E+Q++ E E +K+ +KKEKK ++Q K + +K+ IM
Sbjct: 2274 EGEEKQVEKE------------------EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315
Query: 423 ENLTLKNHFQSVLEQLELQEK-------QKNEKLISLQEQLQRFLK 461
E + + E L+E+ K EK LQEQ ++ L+
Sbjct: 2316 EETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLR 2361
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/197 (23%), Positives = 91/197 (46%), Gaps = 13/197 (6%)
Query: 263 NEVKRLLRSDAEAVSTRWEVIAEDGTKE-IESQGSIPGFLISSGMSSHKQGHTSSEYDML 321
N+ +++ +++ EVI +D + IE + IP + K+ D
Sbjct: 2155 NKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIP--FLKRRWRKRKEAKRG---DKP 2209
Query: 322 REMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQY 381
+E FS + +E +E E ++ ++ E EEE+ EE ER+ + E E +
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE-EEEVREEEEE 2268
Query: 382 RANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQ 441
R E +KQ+EK+E++ K + K ++++++ K E K S E L
Sbjct: 2269 RKEEEEGE-----EKQVEKEEEEKKK-KKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 442 EKQKNEKLISLQEQLQR 458
++++ E+ SL+E++ R
Sbjct: 2323 DEEEEEESCSLEEEVDR 2339
Score = 36.6 bits (83), Expect = 0.049
Identities = 57/251 (22%), Positives = 99/251 (39%), Gaps = 54/251 (21%)
Query: 191 LSPEEPAASTDPNIVRKKER----GREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKE 246
++ EE + + RK EE + + + P LK R+ R RK K+ KE
Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLK--RRWRKRKEAKRGDKPKE 2211
Query: 247 MEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGM 306
S E E++ LL E+E Q S+ SS
Sbjct: 2212 KFSSQVDEVESEEHFSEEMESLL-------------------DELEKQESL-----SSEE 2247
Query: 307 SSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDE-----------DEDEDEDK 355
++ E + +RE + + + +E + +++E+E + E E+
Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF- 2306
Query: 356 EEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEI--QKQIEKKEK--KLHKIQNK 411
EE+EE SEE E E E + S+ E+ +K+I KKEK KL + + K
Sbjct: 2307 EEKEEIMSEEETESLSDEE--------EEEESCSLEEEVDREKEILKKEKQFKLQEQRRK 2358
Query: 412 AQRQKDLIMKV 422
+ R ++ ++ +
Sbjct: 2359 SLRGRERVLSI 2369
Score = 36.2 bits (82), Expect = 0.064
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 317 EYDMLREMFSDSRSNNDDDEDEDD---EDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQA 373
E+ + E S+S +DE++ E+E E E++++ EE+ EE+ ++
Sbjct: 1520 EWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHR 1579
Query: 374 EFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQS 433
+ + + RA E +K +++EK + + AQ ++ L +T + +
Sbjct: 1580 KRARAEKKRAQEE--------RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMA 1631
Query: 434 VLE----QLELQEKQKNEKLISLQEQLQRFLKK 462
E Q E Q+ EKL E+L + KK
Sbjct: 1632 QAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKK 1664
Score = 32.7 bits (73), Expect = 0.71
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 9/144 (6%)
Query: 317 EYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFI 376
E+DM + + N ++E E++ + +E+E + E SEE + + E +
Sbjct: 1722 EWDMEELSWKEEELN----QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL 1777
Query: 377 ESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLE 436
+ + + + E ++ K+E+ + K AQ+++ I +E LT KN +
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELT-KNKMILYQK 1836
Query: 437 QLELQEK----QKNEKLISLQEQL 456
+ QEK Q+ EKL +E L
Sbjct: 1837 KNLAQEKKNLAQEKEKLAQRKENL 1860
Score = 32.3 bits (72), Expect = 0.93
Identities = 15/69 (21%), Positives = 43/69 (62%), Gaps = 3/69 (4%)
Query: 393 EIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENL---TLKNHFQSVLEQLELQEKQKNEKL 449
E +K++ ++E+KLH+ K +++++ + + L K ++++L +++ K+E+
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543
Query: 450 ISLQEQLQR 458
++L+E++ R
Sbjct: 1544 VTLEEEVSR 1552
>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 487
Score = 52.8 bits (125), Expect = 7e-07
Identities = 37/152 (24%), Positives = 74/152 (48%), Gaps = 10/152 (6%)
Query: 225 PLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIES--PDVENEVKRLLRSD-AEAVSTRWE 281
P K KK+F K P+ + S+F Y P ++ E L D A+ + W
Sbjct: 216 PPKGETKKKF-----KDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWN 270
Query: 282 VIAEDGTKEIESQGSIPGFLISSGMSSH--KQGHTSSEYDMLREMFSDSRSNNDDDEDED 339
A D + E + + ++++ K H ++ +++ S + +++E+++
Sbjct: 271 NTAADDKQPYEKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDE 330
Query: 340 DEDEDEDEDEDEDEDKEEEEEDCSEEYLERQL 371
+++E+E ++EDEDE+ +E+EED +E QL
Sbjct: 331 EDEEEEKDEEDEDEEDDEDEEDGDDEQSHWQL 362
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 52.8 bits (125), Expect = 7e-07
Identities = 26/89 (29%), Positives = 48/89 (53%)
Query: 285 EDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDED 344
ED + +E L + +S + +L D +++E+E+DE+E+
Sbjct: 219 EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE 278
Query: 345 EDEDEDEDEDKEEEEEDCSEEYLERQLQA 373
E+E+E+E+E++EEEEE+ EE E + +A
Sbjct: 279 EEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Score = 52.0 bits (123), Expect = 1e-06
Identities = 22/60 (36%), Positives = 41/60 (68%)
Query: 315 SSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAE 374
S E + + S + +++E+E++E+EDE+E+E+E+E++EEEEE+ EE E + + E
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 49.7 bits (117), Expect = 6e-06
Identities = 22/50 (44%), Positives = 37/50 (74%)
Query: 334 DDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRA 383
++EDE++E+E+E+E+EDE+E++EEEEE+ EE E + + E E + A
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Score = 48.5 bits (114), Expect = 1e-05
Identities = 19/42 (45%), Positives = 35/42 (83%)
Query: 333 DDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAE 374
+++E+E++EDE+E+E+E+E+E++EEEEE+ EE E + + E
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 47.4 bits (111), Expect = 3e-05
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 314 TSSEYDMLREMFSDSRSNNDDDE------DEDDEDEDEDEDEDEDEDKEEEEEDCSEEYL 367
T D+ + D+ S + +E+DE+E+E+E+E+E++++EEEEE+ EE
Sbjct: 229 TERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 288
Query: 368 ERQLQAEFIESGQYRANEGTSSIVME 393
E + + E E + E ++ +
Sbjct: 289 EEEEEEEEEEEEEEEEEEAAPDVIFQ 314
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/102 (22%), Positives = 52/102 (50%), Gaps = 7/102 (6%)
Query: 306 MSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
+S ++ E + E + +++E+E++E+E+E+E+E+E+E++EE D
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI-- 312
Query: 366 YLERQLQAEFIESGQYRANEGTS-----SIVMEIQKQIEKKE 402
+ E ++ + R E S S+++E++ +K E
Sbjct: 313 FQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE 354
>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
Length = 619
Score = 52.8 bits (125), Expect = 7e-07
Identities = 18/50 (36%), Positives = 39/50 (78%)
Query: 321 LREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQ 370
+ E D +D ++D+DDED+D++EDE+E+E++EE+++D +E++ +++
Sbjct: 126 IMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQE 175
Score = 48.9 bits (115), Expect = 1e-05
Identities = 17/41 (41%), Positives = 33/41 (80%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYL 367
D + ++DDDED+DDE+++E+E+E+E++D ++ E+ +E L
Sbjct: 137 DDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENL 177
Score = 47.0 bits (110), Expect = 4e-05
Identities = 16/43 (37%), Positives = 32/43 (74%)
Query: 323 EMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
E+ ++D+ EDD+D+++D+DE+++E++EEEEED ++
Sbjct: 125 EIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDD 167
Score = 35.4 bits (80), Expect = 0.11
Identities = 15/50 (30%), Positives = 29/50 (58%)
Query: 312 GHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEED 361
G E D + D ++++DE+E++E+E++D+D+ ED +E D
Sbjct: 130 GGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPD 179
Score = 29.3 bits (64), Expect = 7.9
Identities = 8/38 (21%), Positives = 23/38 (60%)
Query: 327 DSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSE 364
D +++E+E+D+D+D ++ D++ + ++ C +
Sbjct: 150 DEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQ 187
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 52.0 bits (123), Expect = 1e-06
Identities = 48/220 (21%), Positives = 90/220 (40%), Gaps = 18/220 (8%)
Query: 231 KKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKE 290
K + + +K + D K + S Y+E+ + E E K + E + ED +
Sbjct: 189 KGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDID-----FFEDIDSD 243
Query: 291 IESQGSIPGFLISSGMSSHKQGH------TSSEYDMLREMFSDSRSNNDDDEDEDDEDE- 343
+ G + SG SS + S+ D+ + SN +DDE ++E E
Sbjct: 244 EDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEE 303
Query: 344 ------DEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQ 397
DED+D E+ED ++ +E AE ++G + + + +K+
Sbjct: 304 LSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKR 363
Query: 398 IEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQ 437
EK +K+ ++ + +K ++ E K S+LE+
Sbjct: 364 QEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEE 403
Score = 42.4 bits (98), Expect = 9e-04
Identities = 33/120 (27%), Positives = 62/120 (51%), Gaps = 7/120 (5%)
Query: 332 NDDDEDEDDEDEDEDEDEDEDEDKEEEE-EDCSEEYLERQLQAEFIESGQYRANEGTSSI 390
+++ E E+D E E +D+++ ED EEEE D + E +AE R + S
Sbjct: 110 SEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDE 169
Query: 391 VMEIQKQIEKKEKKLHKIQNKAQ---RQKDLIMKVENLTLKNHFQSVLEQLELQEKQKNE 447
++ I K E++ K+QNK Q R+K ++ + + ++ LE +E +E++K++
Sbjct: 170 DSDLDFDISKLEQQ-SKVQNKGQGKPREKSIV--DDKFFKLSEMEAYLENIEKEEERKDD 226
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 51.6 bits (122), Expect = 1e-06
Identities = 57/220 (25%), Positives = 99/220 (45%), Gaps = 35/220 (15%)
Query: 250 SSFTEYIESPDVEN-EVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSS 308
S+F+ I S D E E+ L + D E + KE + S+ G
Sbjct: 521 STFSPTILSSDKETIEIIDLAKKDLEKLKR----------KEKRKKKSVAG--------- 561
Query: 309 HKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLE 368
K+ +T ++ + E R NN+ + +E E D EDE+E++EEEE+D
Sbjct: 562 -KEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDH---EDEEEEEEEEEDDIDGGESS 617
Query: 369 RQLQAEFIESGQYRANEGTSSIVMEI---QKQIEKKEKKLHKIQN-KAQRQKDLIM---K 421
+ +E E Y+A+ ++I EI QK I++ E ++Q K Q ++ L+M K
Sbjct: 618 DESDSESDEKANYQAD--LANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHK 675
Query: 422 VENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLK 461
+ + L+ VL+ L E EK ++ + ++ L+
Sbjct: 676 IRDTQLER--DQVLQNLGSVESYSEEKAKKVRSEYEKKLQ 713
Score = 36.6 bits (83), Expect = 0.049
Identities = 69/333 (20%), Positives = 136/333 (40%), Gaps = 39/333 (11%)
Query: 141 VVEVEDVPLAAKLVDLPCVIESLR------TLDKKTFYKTADISQMLVCTADGDIHLSPE 194
+ E+ED L AKL++ V E+LR T F ++ S ++ + I +
Sbjct: 483 IKEIED--LRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIID- 539
Query: 195 EPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTE 254
A D +++KE+ +++ K T + KK + ++ + E+E+S
Sbjct: 540 --LAKKDLEKLKRKEKRKKKSVAGKEDNTDT--DQEKKEEKGVSERENNELEVEESQEVS 595
Query: 255 YIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTK--------EIESQGSIPGFLISSGM 306
E + E E + D + + E +E K I + +I LI
Sbjct: 596 DHEDEEEEEEEEE---DDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELE 652
Query: 307 SSHKQGHT-SSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEE 365
+S K+ T +Y+ M + + D+ ++ E E++ K+ E
Sbjct: 653 NSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSE----- 707
Query: 366 YLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENL 425
E++LQA E + +A + + +++ Q Q EK+ KKL +Q + MK +
Sbjct: 708 -YEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKL--------QQDVMEMKKTKV 758
Query: 426 TLKNHFQSVLEQLELQEKQKNEKLISLQEQLQR 458
L + E+ L E ++N ++ L++ ++
Sbjct: 759 RLMKQMKEEQEKARLTESRRNREIAQLKKDQRK 791
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 23/189 (12%)
Query: 227 KNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK---RLLRSDA--EAVSTRWE 281
K R+++ R+ QK+ + KE E+ + E + + EV R +R D + ++ W
Sbjct: 162 KRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWS 220
Query: 282 VIAE----------DGTKEIESQGSIPGFLISSGMS-SHKQGHTSSEYDMLREMFSDSRS 330
DG K ++ + L+S S + TSS E S S
Sbjct: 221 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 280
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC---SEEYLER---QLQAEFIESGQYRAN 384
+++E+E++E +E E+E+E++EEEEE+ SEE E+ ++ E + + R N
Sbjct: 281 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 340
Query: 385 EGTSSIVME 393
E +V E
Sbjct: 341 ENHLLVVPE 349
Score = 29.3 bits (64), Expect = 7.9
Identities = 30/166 (18%), Positives = 64/166 (38%), Gaps = 28/166 (16%)
Query: 223 TPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEV 282
+PP + +K V + K E+ ++ + D E + S AE+ S
Sbjct: 222 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGS----- 276
Query: 283 IAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDED 342
G++E E + ++G TS E + E +++E+E++
Sbjct: 277 ----GSEEEEEEEE----------EEEEEGSTSEESEEEEE---------EEEEEEEETG 313
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTS 388
+ +E ++ ++ EEE +E E + + ++ + G S
Sbjct: 314 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 359
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 23/189 (12%)
Query: 227 KNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK---RLLRSDA--EAVSTRWE 281
K R+++ R+ QK+ + KE E+ + E + + EV R +R D + ++ W
Sbjct: 172 KRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWS 230
Query: 282 VIAE----------DGTKEIESQGSIPGFLISSGMS-SHKQGHTSSEYDMLREMFSDSRS 330
DG K ++ + L+S S + TSS E S S
Sbjct: 231 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 290
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC---SEEYLER---QLQAEFIESGQYRAN 384
+++E+E++E +E E+E+E++EEEEE+ SEE E+ ++ E + + R N
Sbjct: 291 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 350
Query: 385 EGTSSIVME 393
E +V E
Sbjct: 351 ENHLLVVPE 359
Score = 29.3 bits (64), Expect = 7.9
Identities = 30/166 (18%), Positives = 64/166 (38%), Gaps = 28/166 (16%)
Query: 223 TPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEV 282
+PP + +K V + K E+ ++ + D E + S AE+ S
Sbjct: 232 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGS----- 286
Query: 283 IAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDED 342
G++E E + ++G TS E + E +++E+E++
Sbjct: 287 ----GSEEEEEEEE----------EEEEEGSTSEESEEEEE---------EEEEEEEETG 323
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTS 388
+ +E ++ ++ EEE +E E + + ++ + G S
Sbjct: 324 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 369
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 23/189 (12%)
Query: 227 KNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK---RLLRSDA--EAVSTRWE 281
K R+++ R+ QK+ + KE E+ + E + + EV R +R D + ++ W
Sbjct: 163 KRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWS 221
Query: 282 VIAE----------DGTKEIESQGSIPGFLISSGMS-SHKQGHTSSEYDMLREMFSDSRS 330
DG K ++ + L+S S + TSS E S S
Sbjct: 222 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 281
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC---SEEYLER---QLQAEFIESGQYRAN 384
+++E+E++E +E E+E+E++EEEEE+ SEE E+ ++ E + + R N
Sbjct: 282 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 341
Query: 385 EGTSSIVME 393
E +V E
Sbjct: 342 ENHLLVVPE 350
Score = 29.3 bits (64), Expect = 7.9
Identities = 30/166 (18%), Positives = 64/166 (38%), Gaps = 28/166 (16%)
Query: 223 TPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEV 282
+PP + +K V + K E+ ++ + D E + S AE+ S
Sbjct: 223 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGS----- 277
Query: 283 IAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDED 342
G++E E + ++G TS E + E +++E+E++
Sbjct: 278 ----GSEEEEEEEE----------EEEEEGSTSEESEEEEE---------EEEEEEEETG 314
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTS 388
+ +E ++ ++ EEE +E E + + ++ + G S
Sbjct: 315 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 360
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 23/189 (12%)
Query: 227 KNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK---RLLRSDA--EAVSTRWE 281
K R+++ R+ QK+ + KE E+ + E + + EV R +R D + ++ W
Sbjct: 140 KRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWS 198
Query: 282 VIAE----------DGTKEIESQGSIPGFLISSGMS-SHKQGHTSSEYDMLREMFSDSRS 330
DG K ++ + L+S S + TSS E S S
Sbjct: 199 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 258
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC---SEEYLER---QLQAEFIESGQYRAN 384
+++E+E++E +E E+E+E++EEEEE+ SEE E+ ++ E + + R N
Sbjct: 259 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 318
Query: 385 EGTSSIVME 393
E +V E
Sbjct: 319 ENHLLVVPE 327
Score = 29.3 bits (64), Expect = 7.9
Identities = 30/166 (18%), Positives = 64/166 (38%), Gaps = 28/166 (16%)
Query: 223 TPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEV 282
+PP + +K V + K E+ ++ + D E + S AE+ S
Sbjct: 200 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGS----- 254
Query: 283 IAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDED 342
G++E E + ++G TS E + E +++E+E++
Sbjct: 255 ----GSEEEEEEEE----------EEEEEGSTSEESEEEEE---------EEEEEEEETG 291
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTS 388
+ +E ++ ++ EEE +E E + + ++ + G S
Sbjct: 292 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 337
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 23/189 (12%)
Query: 227 KNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK---RLLRSDA--EAVSTRWE 281
K R+++ R+ QK+ + KE E+ + E + + EV R +R D + ++ W
Sbjct: 129 KRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWS 187
Query: 282 VIAE----------DGTKEIESQGSIPGFLISSGMS-SHKQGHTSSEYDMLREMFSDSRS 330
DG K ++ + L+S S + TSS E S S
Sbjct: 188 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 247
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC---SEEYLER---QLQAEFIESGQYRAN 384
+++E+E++E +E E+E+E++EEEEE+ SEE E+ ++ E + + R N
Sbjct: 248 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 307
Query: 385 EGTSSIVME 393
E +V E
Sbjct: 308 ENHLLVVPE 316
Score = 29.3 bits (64), Expect = 7.9
Identities = 30/166 (18%), Positives = 64/166 (38%), Gaps = 28/166 (16%)
Query: 223 TPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEV 282
+PP + +K V + K E+ ++ + D E + S AE+ S
Sbjct: 189 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGS----- 243
Query: 283 IAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDED 342
G++E E + ++G TS E + E +++E+E++
Sbjct: 244 ----GSEEEEEEEE----------EEEEEGSTSEESEEEEE---------EEEEEEEETG 280
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTS 388
+ +E ++ ++ EEE +E E + + ++ + G S
Sbjct: 281 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 326
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 23/189 (12%)
Query: 227 KNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK---RLLRSDA--EAVSTRWE 281
K R+++ R+ QK+ + KE E+ + E + + EV R +R D + ++ W
Sbjct: 174 KRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWS 232
Query: 282 VIAE----------DGTKEIESQGSIPGFLISSGMS-SHKQGHTSSEYDMLREMFSDSRS 330
DG K ++ + L+S S + TSS E S S
Sbjct: 233 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 292
Query: 331 NNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDC---SEEYLER---QLQAEFIESGQYRAN 384
+++E+E++E +E E+E+E++EEEEE+ SEE E+ ++ E + + R N
Sbjct: 293 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 352
Query: 385 EGTSSIVME 393
E +V E
Sbjct: 353 ENHLLVVPE 361
Score = 30.8 bits (68), Expect = 2.7
Identities = 44/212 (20%), Positives = 82/212 (38%), Gaps = 16/212 (7%)
Query: 213 EEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVK-RLLRS 271
+EK WK + +++K+ RK Q++ ++K ++ S + E E++ +
Sbjct: 3 DEKDSWKVKTLDEI--LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 272 DAEAVSTRWEVIAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSN 331
R E ED +E +S P +S H H E + R
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVH---HRKDE-----KRKEKRRHR 112
Query: 332 NDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIV 391
+ E E E E E + EE+D + ERQ + E R +
Sbjct: 113 SHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDR----- 167
Query: 392 MEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVE 423
+E ++ ++E+K+ + Q + + QK+ + E
Sbjct: 168 LEQLERKRERERKMREQQKEQREQKERERRAE 199
Score = 29.3 bits (64), Expect = 7.9
Identities = 30/166 (18%), Positives = 64/166 (38%), Gaps = 28/166 (16%)
Query: 223 TPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEV 282
+PP + +K V + K E+ ++ + D E + S AE+ S
Sbjct: 234 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGS----- 288
Query: 283 IAEDGTKEIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDED 342
G++E E + ++G TS E + E +++E+E++
Sbjct: 289 ----GSEEEEEEEE----------EEEEEGSTSEESEEEEE---------EEEEEEEETG 325
Query: 343 EDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTS 388
+ +E ++ ++ EEE +E E + + ++ + G S
Sbjct: 326 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 371
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,060,731
Number of Sequences: 37866
Number of extensions: 923583
Number of successful extensions: 35262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 817
Number of HSP's successfully gapped in prelim test: 663
Number of HSP's that attempted gapping in prelim test: 10169
Number of HSP's gapped (non-prelim): 9716
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.