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Search of human proteins with 51477700
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51477700 mediator complex subunit 15 isoform a [Homo
sapiens]
(788 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 1578 0.0
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 1482 0.0
gi|169164663 PREDICTED: similar to mediator complex subunit 15 [... 129 1e-29
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 128 2e-29
gi|221139761 zinc finger protein 853 [Homo sapiens] 127 3e-29
gi|62953127 polyhomeotic 1-like [Homo sapiens] 123 6e-28
gi|169164745 PREDICTED: similar to hCG2014450 [Homo sapiens] 123 8e-28
gi|169163050 PREDICTED: hypothetical protein LOC100127989 [Homo ... 123 8e-28
gi|169164311 PREDICTED: similar to hCG2014450 [Homo sapiens] 122 2e-27
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 113 8e-25
gi|33286444 mastermind-like 2 [Homo sapiens] 112 1e-24
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 112 2e-24
gi|110347429 mediator complex subunit 12 [Homo sapiens] 112 2e-24
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 111 2e-24
gi|93141033 PAX interacting protein 1 [Homo sapiens] 109 9e-24
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 105 2e-22
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 105 2e-22
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 100 7e-21
gi|226246533 TOX high mobility group box family member 3 isoform... 99 1e-20
gi|226054295 TOX high mobility group box family member 3 isoform... 99 1e-20
gi|56549696 E1A binding protein p400 [Homo sapiens] 97 4e-20
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 97 8e-20
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 96 1e-19
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 93 8e-19
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 93 1e-18
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 91 3e-18
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 90 9e-18
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 89 2e-17
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 89 2e-17
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 89 2e-17
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 1578 bits (4087), Expect = 0.0
Identities = 788/788 (100%), Positives = 788/788 (100%)
Query: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
Query: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ
Sbjct: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
Query: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR
Sbjct: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Query: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Query: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ
Sbjct: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
Query: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQ 420
PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQ
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQ 420
Query: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF 480
PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF
Sbjct: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF 480
Query: 481 LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS 540
LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS
Sbjct: 481 LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS 540
Query: 541 KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA 600
KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA
Sbjct: 541 KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA 600
Query: 601 VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC 660
VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC
Sbjct: 601 VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC 660
Query: 661 TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP 720
TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP
Sbjct: 661 TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP 720
Query: 721 LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV 780
LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV
Sbjct: 721 LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV 780
Query: 781 HQACLSAA 788
HQACLSAA
Sbjct: 781 HQACLSAA 788
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 1482 bits (3836), Expect = 0.0
Identities = 748/788 (94%), Positives = 748/788 (94%), Gaps = 40/788 (5%)
Query: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
Query: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ
Sbjct: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
Query: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR
Sbjct: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Query: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Query: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ
Sbjct: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
Query: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQ 420
PQVQQQQTAVQTAQAAQMVAPGV
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAPGV------------------------------------- 383
Query: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF 480
QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF
Sbjct: 384 ---QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF 440
Query: 481 LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS 540
LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS
Sbjct: 441 LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS 500
Query: 541 KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA 600
KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA
Sbjct: 501 KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA 560
Query: 601 VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC 660
VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC
Sbjct: 561 VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC 620
Query: 661 TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP 720
TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP
Sbjct: 621 TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP 680
Query: 721 LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV 780
LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV
Sbjct: 681 LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV 740
Query: 781 HQACLSAA 788
HQACLSAA
Sbjct: 741 HQACLSAA 748
>gi|169164663 PREDICTED: similar to mediator complex subunit 15
[Homo sapiens]
Length = 229
Score = 129 bits (323), Expect = 1e-29
Identities = 63/90 (70%), Positives = 71/90 (78%), Gaps = 10/90 (11%)
Query: 633 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 682
+FNHSLYR F+P M AIH PPIT APVVCT+K RLEDDE+QSIPSVLQG V
Sbjct: 62 LFNHSLYRIFMPTMIAIHSPPITYIQLGWASQRAPVVCTQKHRLEDDEQQSIPSVLQGLV 121
Query: 683 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 712
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 128 bits (322), Expect = 2e-29
Identities = 140/421 (33%), Positives = 175/421 (41%), Gaps = 93/421 (22%)
Query: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQ---- 157
PP+GP LG Q L Q P PH +++ + + QL Q
Sbjct: 3794 PPQGPQGMLGP-------AQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQG 3846
Query: 158 ------VALQQQQQQQQFQQQ-QQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
V QQQQQQQQ QQQ A L QQ Q + SA +QQQQQL
Sbjct: 3847 LMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQL 3906
Query: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
QQQQQ QQ Q QQQ+QQQQQ LQQQQ QQQQQQQQ QQ Q Q
Sbjct: 3907 QQQQQLQQ-------QQQQQLQQQQQ---------LQQQQLQQQQQQQQLQQQQQQQLQQ 3950
Query: 271 QQPPMQQPQPPPSQALPQQLQQ-----MHHTQHHQPPPQPQQPPVAQ------------N 313
QQ +QQ Q Q QQ QQ ++ ++ P Q QQ VA +
Sbjct: 3951 QQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFS 4010
Query: 314 QPSQLPP--------QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPP------- 358
P L P Q+ P VS ++A G + PL P + P
Sbjct: 4011 SPGALGPTLLLTGKEQNTVDPAVS-SEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSL 4069
Query: 359 --------VQPQVQQQQTAVQTAQAAQMVAPGVQMITEAL---AQGGMHIRARFPPTTAV 407
VQPQ Q Q +++Q ++ PG Q +L A GG H + ++
Sbjct: 4070 SGDSQLLLVQPQPQPQPSSLQLQPPLRL--PGQQQQQVSLLHTAGGGSHGQLGSGSSSEA 4127
Query: 408 SAIP----SSSIPLGRQPMAQVSQSSL----PMLSSPSPGQQVQTPQSMPPPPQPSPQPG 459
S++P S+ LG QP ++Q+ L PML P Q PQ PP P P Q G
Sbjct: 4128 SSVPHLLAQPSVSLGDQP-GSMTQNLLGPQQPMLERPM--QNNTGPQ--PPKPGPVLQSG 4182
Query: 460 Q 460
Q
Sbjct: 4183 Q 4183
Score = 112 bits (281), Expect = 1e-24
Identities = 169/611 (27%), Positives = 217/611 (35%), Gaps = 177/611 (28%)
Query: 81 PMNALQSLTGGPAAGAAGIGMPPRG---PGQSLGGM--------------GSLGAMGQPM 123
P + LQ G P A G+ + P G PGQ G G G++ P
Sbjct: 3637 PGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGP- 3695
Query: 124 SLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQ-----QQQQQQQFQQQQ---QA 175
SG PG +A S+ S + QLQLQQ +Q QQQQQQQ QQQ Q
Sbjct: 3696 --SGGFFPGN--LALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQV 3751
Query: 176 ALQQQQQQQQQQQFQ--------------------------------------AQQSAMQ 197
A+QQQQQQ Q AQ + +Q
Sbjct: 3752 AIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQ 3811
Query: 198 QQF-----------QAVVQQQQQLQQQQQQQQ-------HLIKLHHQNQQQIQQQQ---- 235
QQ Q ++ Q + L Q QQ L+ Q QQQ QQQ
Sbjct: 3812 QQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMA 3871
Query: 236 --------------------------QQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP 269
QQLQ+ QLQ QQQ QQQQQQQ QQQQ LQ Q
Sbjct: 3872 GLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQL 3931
Query: 270 IQQPPMQQPQPPPSQALPQQLQQMHHTQHH-----QPPPQPQQPPVAQNQPSQLPPQSQT 324
QQ QQ Q Q L QQ QQ+ Q Q Q QQ + + L PQ Q
Sbjct: 3932 QQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQ 3991
Query: 325 QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
Q V+ +P + PL+ +P + P + ++Q T + P
Sbjct: 3992 QQQVALGPGMPAK------PLQHFSSPGAL-GPTLLLTGKEQNTVDPAVSSEATEGPSTH 4044
Query: 385 MITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQT 444
QGG A+ P S + +S S +L P P Q +
Sbjct: 4045 -------QGG---------PLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSS 4088
Query: 445 PQSMPPPPQPSPQPGQPS------SQPNSNVSSGPAPSPSSFLPSPSPQPS--------- 489
Q PP P Q Q S + + SG + S +S +P QPS
Sbjct: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSG-SSSEASSVPHLLAQPSVSLGDQPGS 4147
Query: 490 --------QSPVTARTPQNFSVPSPGPLNTPVNPS-------SVMSPAGSSQAEEQQYLD 534
Q P+ R QN + P P P PV S +M G +A+ Q L
Sbjct: 4148 MTQNLLGPQQPMLERPMQNNTGPQP-PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA 4206
Query: 535 KLKQLSKYIEP 545
K QL +++ P
Sbjct: 4207 KNPQL-RHLSP 4216
Score = 65.9 bits (159), Expect = 1e-10
Identities = 108/428 (25%), Positives = 160/428 (37%), Gaps = 88/428 (20%)
Query: 86 QSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVS 145
Q L+GGP++ G G + G P PP G+ +
Sbjct: 3460 QRLSGGPSSDLQN---------HVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQY 3510
Query: 146 TATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQ 205
QL Q+ L+ ++Q ++ + AL +Q+ ++ + + A ++ + V +
Sbjct: 3511 EEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPE-ADAEKLKLVTE 3569
Query: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQ-QAL 264
QQ ++Q+Q Q + +QQ++ +A+ + +QQQQQQQQQQQQQQ A+
Sbjct: 3570 QQSKIQKQLDQVR-------------KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAV 3616
Query: 265 QAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT 324
A P Q P + LP QL H Q PQ PP Q +L P
Sbjct: 3617 LALSPSQSPRL-------LTKLPGQLLPGHGLQ------PPQGPPGGQAGGLRLTP---- 3659
Query: 325 QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
ALPG QP F+ + QQ QQQ + A + P
Sbjct: 3660 -----GGMALPG-----QPGGPFLNTALAQQQ-------QQQ----HSGGAGSLAGP--- 3695
Query: 385 MITEALAQGGMHIRARFPPTTAVSAI-PSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443
GG FP A+ ++ P S + RQ Q+ Q + + QQ Q
Sbjct: 3696 -------SGGF-----FPGNLALRSLGPDSRLLQERQ--LQLQQQRMQLAQKLQQQQQQQ 3741
Query: 444 TPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPS----PSS----FLPSPSPQPSQSPVTA 495
Q Q Q +N + GP P PSS + SPQP Q P
Sbjct: 3742 QQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGM 3801
Query: 496 RTPQNFSV 503
P +V
Sbjct: 3802 LGPAQVAV 3809
Score = 60.8 bits (146), Expect = 5e-09
Identities = 148/632 (23%), Positives = 217/632 (34%), Gaps = 131/632 (20%)
Query: 90 GGPAAGAAGIGMPPRG----PGQ---SLGGMGSL-----GAMGQPMSLSGQPPPGTSGMA 137
GGP A IG P PG+ SL G L QP SL QPP G
Sbjct: 4046 GGPLA----IGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQ 4101
Query: 138 PHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ 197
++++ TA + QL + + Q +L Q Q QQ ++
Sbjct: 4102 QQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLE 4161
Query: 198 QQFQ-----------AVVQQQQQLQ---------QQQQQQQHLIKLHHQNQQQIQQQQQQ 237
+ Q V+Q Q L Q + Q Q ++ + Q + QQQQQ
Sbjct: 4162 RPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQ 4221
Query: 238 LQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP-----PMQ-----QPQP---PPSQ 284
LQ + Q+Q QQ QA++ PP Q+P P+Q QPQ P Q
Sbjct: 4222 LQALLM-----------QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270
Query: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS-QAQALPGQMLYTQP 343
P LQ++ Q PP+ PP A + L P T P S Q P Q+
Sbjct: 4271 TGP--LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL----- 4323
Query: 344 PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPP 403
P + P Q PP P + Q + V+P + + L G + PP
Sbjct: 4324 PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR-VSPAAAQLADTLFSKG--LGPWDPP 4380
Query: 404 TTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS 463
L + QV+ +P S S Q+ P + G S
Sbjct: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQE---------PREEPCALGAQSV 4431
Query: 464 QPNSNVSSGPAPSPSSFLPSPSPQPS------QSPVTARTPQNFSVPSPGPLNTPVNPSS 517
+ +N AP S+ L P+ Q + A+ Q + L +N
Sbjct: 4432 KREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHI 4491
Query: 518 VMSPAGSSQ------------AEEQQYLDKLKQLSKYIEPL---RRMINKID---KNEDR 559
AG Q A + K K++ K + L R+ + K D +E
Sbjct: 4492 DSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEAL 4551
Query: 560 KKDLSKMKSLLDILTDPS------------KRCPLKTLQKCEIALEK------------- 594
K L + SLL LT+P+ CP+ + A
Sbjct: 4552 LKQLKQELSLLP-LTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQL 4610
Query: 595 -LKNDMAVPTPPPPPVPPTKQQYLCQPLLDAV 625
KN+++ P PP +PPT + Q +++ V
Sbjct: 4611 LTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGV 4642
Score = 59.7 bits (143), Expect = 1e-08
Identities = 78/338 (23%), Positives = 126/338 (37%), Gaps = 50/338 (14%)
Query: 212 QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ 271
Q Q + H+ + + +Q + + L + A +QL+ Q + ++ + + P+
Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGK-AGVQLEPQLEAPLNEEMPLLPPPE-ESPLS 450
Query: 272 QPPMQQPQPPPSQAL-----PQQL--QQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQS 322
PP + P PP +A P++L + H P + P PP ++ S P S
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS 510
Query: 323 QTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV--QQPPVQPQVQQQQTAVQTAQAAQMVA 380
PL + P + PP + P+ + P+ P ++ + +
Sbjct: 511 PFSPLEESPLSPPEE----SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP 566
Query: 381 PGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQ 440
P ++ PP + + P P+ P A S+ P SP
Sbjct: 567 PEASRLSP-------------PPEESPMSPPPEESPMSPPPEA--SRLFPPFEESPLSPP 611
Query: 441 QVQTPQSMPP-------PPQPSPQPGQPSSQPNS---NVSS-GPAPSPSSFLPSP----- 484
++P S PP PP+ SP P P S VS P P S P P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 485 SPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 522
SP P +SP + P S SP P ++P +P SPA
Sbjct: 672 SPPPEESPTS--PPPEASRLSPPPEDSPTSPPPEDSPA 707
Score = 57.4 bits (137), Expect = 5e-08
Identities = 67/280 (23%), Positives = 106/280 (37%), Gaps = 38/280 (13%)
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQP------PIQQPPMQQPQPPPSQALPQQLQQMHHT 296
+L L Q ++ ++ L QP P + P P+P S P+ +
Sbjct: 803 ELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSP 862
Query: 297 QHHQPPPQPQQPPVAQNQPSQLPP-QSQTQPLVSQ-AQALPGQMLYTQPPLKFVRAPMVV 354
+ +PP +P Q P + P PP + PL+ + A + PG+ + P + +P
Sbjct: 863 RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPS-- 920
Query: 355 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSS 414
+P + PQ+ + P + I A A PP A+S +
Sbjct: 921 GEPSLSPQLMPPDP----------LPPPLSPIITAAA----------PP--ALSPLGELE 958
Query: 415 IPLGRQ----PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVS 470
P G + P + ++ L SP P P+ +PP P P PG P P S +
Sbjct: 959 YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP-PSPGSPVG-PASPIL 1016
Query: 471 SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLN 510
P P S L S P SP + +P + P PL+
Sbjct: 1017 MEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS 1056
Score = 57.0 bits (136), Expect = 7e-08
Identities = 59/262 (22%), Positives = 96/262 (36%), Gaps = 32/262 (12%)
Query: 267 QPPIQQPPMQQPQPPPSQALP-QQLQQMHHTQHHQPPPQP--QQPPVAQNQPSQLPPQSQ 323
+ P+ PP + P PP ++ P L++ + + PP P + P + S L P +
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550
Query: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
PL + LP T PP + R ++ P+ P ++ + +A+++ P
Sbjct: 551 ESPLSPPPEELP-----TSPPPEASRLSPPPEESPMSPPPEESPMS-PPPEASRLFPPFE 604
Query: 384 QMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443
+ L+ PP + + P P+ P + S P +S SP +
Sbjct: 605 E---SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP-EESPMSPPPEVSRLSP---LP 657
Query: 444 TPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSV 503
+ PPP+ SP P P S P P S P P P+ P
Sbjct: 658 VVSRLSPPPEESPLSPPPEESPTS-----PPPEASRLSPPPEDSPTSPP----------- 701
Query: 504 PSPGPLNTPVNPSSVMSPAGSS 525
P P + P S + P S
Sbjct: 702 PEDSPASPPPEDSLMSLPLEES 723
Score = 55.1 bits (131), Expect = 3e-07
Identities = 65/263 (24%), Positives = 100/263 (38%), Gaps = 56/263 (21%)
Query: 231 IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQL 290
++ ++++LQ+ QL Q Q QQQQQQQQQ L A P Q + PS A QQ
Sbjct: 3253 LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQ 3312
Query: 291 QQMHHTQHHQP----PPQPQQPP-------------VAQNQ----------PSQLPPQSQ 323
+ QP P P QPP + NQ + L PQ
Sbjct: 3313 LSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQS 3372
Query: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ--------PPVQPQVQQQQTAVQTAQA 375
+QP++SQ + + T PP ++ + Q P + +
Sbjct: 3373 SQPVLSQ------KPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAK 3426
Query: 376 AQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSS 435
A+MVA ++ I + +AQG + + + + L Q ++ S L +
Sbjct: 3427 AKMVA--LKGIKKVMAQGSIGV---------APGMNRQQVSLLAQRLSGGPSSDLQNHVA 3475
Query: 436 PSPGQQVQTPQSMPPPPQPSPQP 458
GQ+ +S P QP P P
Sbjct: 3476 AGSGQE----RSAGDPSQPRPNP 3494
Score = 52.4 bits (124), Expect = 2e-06
Identities = 70/300 (23%), Positives = 113/300 (37%), Gaps = 55/300 (18%)
Query: 262 QALQAQPPIQQPPMQQPQPPPSQAL-------PQQLQQMHHTQHH-QPPPQPQQPPVAQN 313
+A Q +P ++ +PPP+QAL P + +T + QPP P+ P
Sbjct: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE 2393
Query: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL--------KFVRAPMV--------VQQP 357
LPP+S S+ A P +Q PL F +P+ +P
Sbjct: 2394 SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453
Query: 358 PVQPQVQQQQTAVQ---TAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSS 414
P +PQ + + Q ++ + +L GG P + A
Sbjct: 2454 PSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHA----K 2509
Query: 415 IPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPP--PQPSPQPGQPSSQP-NSNVSS 471
+P G+ P S + + +PSP + PQ++ P P PQPG P NS+
Sbjct: 2510 VPSGQPPNFVRSPGTGAFVGTPSP-MRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGP 2568
Query: 472 GP----------APSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSP 521
GP + +F PS SP P + T +++ + +P+ P SV+ P
Sbjct: 2569 GPTLGKPQSTNYTVATGNFHPSGSP---LGPSSGSTGESYGL-------SPLRPPSVLPP 2618
Score = 49.3 bits (116), Expect = 1e-05
Identities = 55/233 (23%), Positives = 86/233 (36%), Gaps = 45/233 (19%)
Query: 302 PPQPQQPPVAQNQPSQLPPQSQTQP----LVSQAQALPGQMLYTQPPLKFVRAPMVVQQP 357
PP+P P ++P L Q QP + S PG + PL + +P
Sbjct: 374 PPEPGDTPT--DEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL---EP 428
Query: 358 PVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPL 417
++ + ++ + + + + P + T PP + + P +P
Sbjct: 429 QLEAPLNEEMPLLPPPEESPLSPPPEESPTSP------------PPEASRLSPPPEELPA 476
Query: 418 GRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSP 477
P+ + S P+ SP + PPP+ SP P S P S + P P
Sbjct: 477 S--PLPEALHLSRPLEESP-----------LSPPPEESPLSPPPESSPFSPLEESPLSPP 523
Query: 478 SSFLPSP------SPQPSQSPVTARTPQNFSVPSPGPLNTPVNP---SSVMSP 521
PSP SP P SP++ P S SP P P +P +S +SP
Sbjct: 524 EESPPSPALETPLSPPPEASPLS--PPFEESPLSPPPEELPTSPPPEASRLSP 574
Score = 48.1 bits (113), Expect = 3e-05
Identities = 62/238 (26%), Positives = 87/238 (36%), Gaps = 31/238 (13%)
Query: 301 PPP--------QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
PPP + ++ + + PS PP S L G L T K AP+
Sbjct: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFK---APL 2331
Query: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQM---------ITEALAQGGMHIRARFPP 403
+ V+PQ Q AQ +AP T+ AQ + R + PP
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 404 TTAVSAIPSSSI---PLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP-G 459
+ A+P S+ P R P + SQSS +P P S P SP P
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451
Query: 460 QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPG-PLNTPVNPS 516
+P S+P S P P P PQP + A + + S+ + G P P P+
Sbjct: 2452 RPPSRPQSRDPFAPLHKP------PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
Score = 47.0 bits (110), Expect = 7e-05
Identities = 55/217 (25%), Positives = 80/217 (36%), Gaps = 17/217 (7%)
Query: 89 TGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTAT 148
TGGP A P GPG S + ++L G P + ++V++
Sbjct: 3188 TGGPPAHLL-TPSPLSGPGGS-SLLEKFELESGALTLPGGPAASGDELDKMESSLVASEL 3245
Query: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF------QA 202
P L + ++ Q++QQ Q Q A QQQQQQQQ A A +
Sbjct: 3246 PLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPS 3305
Query: 203 VVQQQQQLQ------QQQQQQQHLIKLH---HQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253
+ QQQL +Q Q L+ H QQ++ + + Q Q
Sbjct: 3306 LAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQA 3365
Query: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQL 290
QQ Q + +Q P+ P P A+ QQL
Sbjct: 3366 GLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQL 3402
Score = 46.6 bits (109), Expect = 9e-05
Identities = 59/259 (22%), Positives = 103/259 (39%), Gaps = 21/259 (8%)
Query: 269 PIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQSQ--T 324
P+ PP + P PP + +L + PPP+ P PP + P+ PP++ +
Sbjct: 634 PMSPPPEESPMSPPPEV--SRLSPLPVVSRLSPPPEESPLSPP-PEESPTSPPPEASRLS 690
Query: 325 QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
P + P + PP + + +++ P+ P ++ Q ++ P
Sbjct: 691 PPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP 750
Query: 385 MITEALAQGGMHIRARFPPTTAVSAIPS-SSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443
++ + + +A P + P ++P +P Q+ P LS P P +
Sbjct: 751 HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP--EEPHLS-PQAEGPHLS-PQPEELHL 806
Query: 444 TPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSV 503
+PQ+ P P P+ S QP + SP S P SP+P +S + +P+
Sbjct: 807 SPQTEEPHLSPVPEEPCLSPQPEES-----HLSPQSEEPCLSPRPEESHL---SPELEKP 858
Query: 504 P-SPGPLNTPVNPSSVMSP 521
P SP P P P +P
Sbjct: 859 PLSPRPEKPPEEPGQCPAP 877
Score = 46.2 bits (108), Expect = 1e-04
Identities = 71/312 (22%), Positives = 122/312 (39%), Gaps = 45/312 (14%)
Query: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQ---QPQPPPSQALPQQ 289
++Q+Q QR+ +L ++QQ Q+ +Q+++ A A PP +P P + L +
Sbjct: 2678 EKQRQRQRLRELLIRQQIQRNTLRQEKETAA--AAAGAVGPPGSWGAEPSSPAFEQLSRG 2735
Query: 290 LQQMHHTQHHQP----PPQPQQPPV-------AQNQPSQLPPQSQTQPLVSQAQALPG-- 336
TQ PP P+ + ++ S+ PP + + ++ L G
Sbjct: 2736 QTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS 2795
Query: 337 QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV----APGVQMITEALAQ 392
Q Y + P + +QQ Q QQQ TA + + A PG ++ +AL
Sbjct: 2796 QAFYQRAPYP---GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS 2852
Query: 393 GGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQ-QVQTPQSMPPP 451
I R P +P + P + Q L +P PGQ Q P+ P
Sbjct: 2853 PLAGISTRLPGPG--EPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVS 2910
Query: 452 PQP---SPQ-----------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 497
P +P+ P +PS+ P +++ P+P + P+ P+ + R
Sbjct: 2911 EDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPT---LPTGLELVNRP 2967
Query: 498 PQNFSVPSPGPL 509
P + + P PL
Sbjct: 2968 PSSTELGRPNPL 2979
Score = 45.8 bits (107), Expect = 2e-04
Identities = 59/242 (24%), Positives = 97/242 (40%), Gaps = 30/242 (12%)
Query: 304 QPQQPPVAQNQPSQLPP-QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV--QQPPVQ 360
QP+ V QP + P Q + +PL L Q+ + PL P++ ++ P+
Sbjct: 395 QPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL---EAPLN-EEMPLLPPPEESPLS 450
Query: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARF-------PPTTAVSAIPSS 413
P ++ T+ +A+++ P ++ L + +H+ PP + + P
Sbjct: 451 PPPEESPTS-PPPEASRLSPPPEELPASPLPEA-LHLSRPLEESPLSPPPEESPLSPPPE 508
Query: 414 SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ--PSSQPNSNVSS 471
S P P+ + S S P S PSP ++TP S PP P P + P S P + +
Sbjct: 509 SSPFS--PLEE-SPLSPPEESPPSPA--LETPLSPPPEASPLSPPFEESPLSPPPEELPT 563
Query: 472 GPAPSPSSFLP-------SPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 524
P P S P SP P+ S + F PL+ P S + P +
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623
Query: 525 SQ 526
S+
Sbjct: 624 SR 625
Score = 40.4 bits (93), Expect = 0.006
Identities = 51/252 (20%), Positives = 87/252 (34%), Gaps = 30/252 (11%)
Query: 268 PPIQQPPMQQPQPPPSQALPQQLQ-----QMHHTQHHQPP---PQPQQPPVAQNQPSQLP 319
P + +P + +P PP LP++L + + PP P P P + P L
Sbjct: 893 PLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALS 952
Query: 320 PQSQTQ-PLVSQAQALPGQMLYT---QPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
P + + P ++ + P L + P+ PV P + A
Sbjct: 953 PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPA 1012
Query: 376 AQMVAPGVQMITEALAQGGMHIRARFP----PTTAVSAIPSSSIPLGR----QPMAQVSQ 427
+ ++ + L Q + + P P ++PS P+G+ A++ +
Sbjct: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072
Query: 428 SSLPMLSSPS-PGQQVQTPQSMPPP------PQPSPQPGQPSSQPNSNVSSGPAPSPSSF 480
+S P P + +P P P PSP P S + AP
Sbjct: 1073 METEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDF---SGLGEDTAPLDGID 1129
Query: 481 LPSPSPQPSQSP 492
P P+P Q+P
Sbjct: 1130 APGSQPEPGQTP 1141
Score = 39.7 bits (91), Expect = 0.011
Identities = 59/248 (23%), Positives = 91/248 (36%), Gaps = 20/248 (8%)
Query: 99 IGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGT-SGMAPHSMAVVSTATPQTQLQLQQ 157
+G+PP + G GS + + LS PPP T S M +S +V + Q
Sbjct: 2749 VGLPPSKLSGPILGPGSFPSDDR---LSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYP 2805
Query: 158 VALQQQQQQQQFQQQQQAALQQQQQQQQQQQF----------QAQQSAMQQQFQAVVQQQ 207
+L QQQQQQ QQQQA + +F QA S + +
Sbjct: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG 2865
Query: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
+ + Q I+L H Q+ + Q + + + + L+
Sbjct: 2866 EPVPGPAGPAQ-FIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGL 2924
Query: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPL 327
PP Q+P PP+ P+ +H T H + P P + N+P + PL
Sbjct: 2925 AVSGLPP-QKPSAPPA---PELNNSLHPTPHTKGPTLPTGLELV-NRPPSSTELGRPNPL 2979
Query: 328 VSQAQALP 335
+A LP
Sbjct: 2980 ALEAGKLP 2987
Score = 36.6 bits (83), Expect = 0.093
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 450 PPPQPSPQPGQPSSQPNSNVSS-------GPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 502
P P+P Q + N +V P+P PS PSP+ P++ V T
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 503 VPSPGPLNTPVNPSSVMSPAGSSQAE--EQQYLDKLKQLSKYIEPLRRMINKIDKNEDRK 560
P P PL +P S + E E +LK+ R++ I K R+
Sbjct: 4944 PPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQ 5003
Query: 561 KDLSKMKSLLDIL 573
+D ++ ++ L
Sbjct: 5004 EDEREVAEFMEQL 5016
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 6/71 (8%)
Query: 447 SMPPPPQPSPQPG----QPSSQPNSNVSSGPAPSPSSFLPSPSPQP-SQSPVTARTPQNF 501
S PPP +PSP P P+S P + P P + P PSP P + SP +AR
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPT-EPLAEPPVPSPLPLASSPESARPKPRA 4965
Query: 502 SVPSPGPLNTP 512
P G + P
Sbjct: 4966 RPPEEGEDSRP 4976
Score = 34.3 bits (77), Expect = 0.46
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 411 PSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNV 469
P+ P VS + LS+P P + +P P P P+ P +P + P +
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP--SPPPSPLAPSPASPPTEPLVELPTEPL 4941
Query: 470 SSGPAPSPSSFLPSPS---PQPSQSP 492
+ P PSP SP P+P P
Sbjct: 4942 AEPPVPSPLPLASSPESARPKPRARP 4967
Score = 34.3 bits (77), Expect = 0.46
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 9/84 (10%)
Query: 278 PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQ 337
P+PP + + + Q PPP+ PP + PS P T+PLV LP +
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS--PASPPTEPLVE----LPTE 4939
Query: 338 MLYTQP---PLKFVRAPMVVQQPP 358
L P PL +P + P
Sbjct: 4940 PLAEPPVPSPLPLASSPESARPKP 4963
Score = 33.9 bits (76), Expect = 0.60
Identities = 77/405 (19%), Positives = 129/405 (31%), Gaps = 36/405 (8%)
Query: 120 GQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQ----- 174
G+P S P G+ G P + +T L Q +LQ+ ++ ++ Q
Sbjct: 1967 GEPDS----PWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVL 2022
Query: 175 -AALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ 233
A + +Q + ++ + + ++ V + Q+ + ++ Q+Q +
Sbjct: 2023 YANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAES 2082
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQM 293
Q + ++ + + + + Q AL + PP P + P L
Sbjct: 2083 QINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGF 2142
Query: 294 HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV 353
P + P Q+P Q +Q A A P + P
Sbjct: 2143 LKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE-------------PRF 2189
Query: 354 VQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSS 413
PP P T AQ G A G H PP T PS+
Sbjct: 2190 PTAPPTYPPYPSP-----TGAPAQPPMLGASSRPGAGQPGEFHTT---PPGTPRHQ-PST 2240
Query: 414 SIPLGRQPMAQVSQSSLPMLSSPSPGQ-QVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 472
P + + ++P SP G + P PPP S + + + S
Sbjct: 2241 PDPFLKPRCPSLDNLAVP--ESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPS 2298
Query: 473 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 517
P F+ SPS + +TP F P P + V P S
Sbjct: 2299 YGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT-PRASQVEPQS 2342
Score = 31.2 bits (69), Expect = 3.9
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 270 IQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS 329
+ PP ++P PPPS P P +PPV PS LP S +
Sbjct: 4906 LSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPV----PSPLPLASSPESARP 4961
Query: 330 QAQALP 335
+ +A P
Sbjct: 4962 KPRARP 4967
Score = 30.4 bits (67), Expect = 6.7
Identities = 55/263 (20%), Positives = 94/263 (35%), Gaps = 32/263 (12%)
Query: 303 PQPQQPPVAQ-NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV----VQQP 357
P+ + PP A ++P + +P V + P +T K AP +
Sbjct: 3096 PEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLK 3155
Query: 358 PVQPQVQQQQTAV---------QTAQAAQMVAPG---VQMITEA--LAQGGMHIRARFPP 403
P Q + + T + TA+ A A G ++T + GG + +F
Sbjct: 3156 PGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFEL 3215
Query: 404 TTAVSAIPSSSIPLGRQPMAQVSQ---SSLPMLSSP---SPGQQVQTPQSMPPPPQPSPQ 457
+ +P G + S S LP+L +++Q Q + QP+ Q
Sbjct: 3216 ESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQ 3275
Query: 458 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 517
Q Q ++ S P P+ + L P SP A + Q S+ G P P
Sbjct: 3276 --QQQQQQQHSLLSAPGPAQAMSL----PHEGSSPSLAGSQQQLSLGLAG-ARQPGLPQP 3328
Query: 518 VMSPAGSSQAEEQQYLDKLKQLS 540
+M + A +Q+ + +S
Sbjct: 3329 LMPTQPPAHALQQRLAPSMAMVS 3351
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 127 bits (320), Expect = 3e-29
Identities = 117/310 (37%), Positives = 149/310 (48%), Gaps = 48/310 (15%)
Query: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQ 209
QTQ +Q LQQQ+Q QQ Q+QQ QQQ+Q QQQQ Q Q+ QQQFQ QQQ+Q
Sbjct: 178 QTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQ---QQQEQ 234
Query: 210 LQQQQQ----QQQHLIK--LHHQNQQQIQQQ---QQQLQRIAQLQLQQQQQQQQQQQQQ- 259
LQQQQQ QQQ ++ L Q Q Q+QQQ QQQ Q QL LQQQ+Q QQQQQQQ
Sbjct: 235 LQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Query: 260 -QQQALQAQPPIQQPPMQQPQP---------PPSQALPQQLQQMHHTQHHQPPPQPQQPP 309
QQQ Q Q QPP +P+ P Q+L+Q Q + QQ
Sbjct: 295 LQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQ-- 352
Query: 310 VAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ-------PPVQPQ 362
+ + QL Q + Q L Q + Q+ + L+ + QQ PVQP+
Sbjct: 353 --EQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPE 410
Query: 363 VQQQ--------QTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSS 414
+Q + AV A AA +VAP ++ + L M + A P AV AIP +
Sbjct: 411 LQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQEL----MVLPAVAAP--AVVAIPGPA 464
Query: 415 IPLGRQPMAQ 424
P Q
Sbjct: 465 GSAALTPARQ 474
Score = 124 bits (312), Expect = 3e-28
Identities = 98/240 (40%), Positives = 124/240 (51%), Gaps = 13/240 (5%)
Query: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQ---QQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Q QLQ QQV QQ+ QQQQ Q Q Q A +QQ QQ+Q QQQ Q QQ QQQ Q +QQ
Sbjct: 156 QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQ--LQQ 213
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
QQ LQQQ+Q QQ + Q Q+Q+QQQQQ L Q QLQQQ QQQQ Q QQQ Q
Sbjct: 214 QQLLQQQEQLQQQQFQ---QQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQ 270
Query: 267 QPPIQQPPMQQPQPPPSQALPQQL--QQMHHTQHHQPPPQPQQPPVAQNQPSQLPP--QS 322
Q +QQ + Q Q Q QQL QQ Q Q P P +P + +L P
Sbjct: 271 QAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLG 330
Query: 323 QTQPLVSQAQALPGQM-LYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAP 381
Q L Q Q L Q L Q + ++ + + ++ Q++QQQ ++ + + P
Sbjct: 331 SEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTP 390
Score = 114 bits (286), Expect = 3e-25
Identities = 108/299 (36%), Positives = 134/299 (44%), Gaps = 52/299 (17%)
Query: 105 GPGQSLGGMGSLGAMGQ----PMSLSGQPP-PGTSGMAPHSMAVVSTATPQTQLQLQQVA 159
GPG GS G+ Q P + P P S S T Q +LQLQQ+
Sbjct: 36 GPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLE 95
Query: 160 LQQQQQQQ-QFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ-FQAV-----------VQQ 206
Q + QQQ Q +Q QQ + QQQ QQ Q Q S +QQ+ Q+V + Q
Sbjct: 96 QQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQ 155
Query: 207 QQQLQQQQ-QQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ---QQQQ 262
QQQLQ QQ Q+QQ L + Q Q Q Q+QQ LQ+ QLQ Q Q+QQ QQQQ QQQQ
Sbjct: 156 QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQ 215
Query: 263 ALQAQPPIQQPPMQQPQPPPSQ-----------ALPQQLQQMHHTQHHQPPPQPQQPPVA 311
LQ Q +QQ QQ Q Q L QQL Q Q Q + QQ +
Sbjct: 216 LLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQ 275
Query: 312 Q----NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ 366
Q Q QL Q Q Q L Q + L Q L Q PP++P+ +++
Sbjct: 276 QQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQL---------------QPPPLEPEEEEE 319
Score = 79.7 bits (195), Expect = 1e-14
Identities = 84/292 (28%), Positives = 121/292 (41%), Gaps = 40/292 (13%)
Query: 128 QPPPGTSGMAPHSMAVVSTATPQTQLQ-----------LQQVALQQQQQQQQFQQQQQAA 176
QP PG G+ +T T +LQ L + + Q+++ Q++ ++
Sbjct: 4 QPTPGNRGLTARMEVGPATETFVLELQCLEDGGPGPDTLSGGSGGSESQEEEEPQERNSS 63
Query: 177 LQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ--QQQLQQQQQQQQHL------IKLHHQNQ 228
Q+ + + Q + +QQ QQ QQQ Q + L ++L Q Q
Sbjct: 64 PQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQ 123
Query: 229 QQIQQQQQQLQR------------------IAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
Q QQQ QLQ+ Q QLQ QQ Q+QQ+ QQQQ+ LQ Q
Sbjct: 124 QDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ 183
Query: 271 QQPPMQQPQPPPSQALPQQL--QQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
+Q +QQ + Q QQL QQ Q Q Q +Q Q Q Q Q Q Q L+
Sbjct: 184 EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLL 243
Query: 329 SQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQ-VQQQQTAVQTAQAAQMV 379
Q Q Q L Q + + + QQ +Q Q + QQQ +Q Q Q++
Sbjct: 244 LQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLL 295
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 123 bits (309), Expect = 6e-28
Identities = 142/541 (26%), Positives = 215/541 (39%), Gaps = 103/541 (19%)
Query: 86 QSLTGGPAAGAAGIGMP----PRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM 141
QSL A G +G +P P G GQ+ GG+G L + G M P GT + P
Sbjct: 260 QSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSG--MGGGSCPRKGTGVVQPLPA 317
Query: 142 AVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQ 201
A T + +Q + + A ++ + QQ L + Q + + Q Q
Sbjct: 318 AQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPH 377
Query: 202 AVVQQQQQLQQQQQQQ--QHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQ 259
+++QQQQQ+ QQ+Q Q I +HHQ QQ Q +Q QL A QQQQQQQQQQQ
Sbjct: 378 SLIQQQQQIHLQQKQVVIQQQIAIHHQ--QQFQHRQSQLLHTATHLQLAQQQQQQQQQQQ 435
Query: 260 QQQALQAQPPIQQPPMQQPQPPPSQAL-PQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318
QQQ QA + P Q PQ PP+Q + P Q QQ T Q P+ Q+ P L
Sbjct: 436 QQQQPQA-TTLTAP--QPPQVPPTQQVPPSQSQQQAQTLVVQ--------PMLQSSPLSL 484
Query: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV-------VQQPPVQPQVQQQQTAVQ 371
PP + +P + + ++PP+ ++ P + QQPP P + Q +
Sbjct: 485 PPDAAPKPPIP---------IQSKPPVAPIKPPQLGAAKMSAAQQPP--PHIPVQVVGTR 533
Query: 372 TAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLP 431
AQ A G+ + +A+P+S G Q +S P
Sbjct: 534 QPGTAQAQALGLAQL--------------------AAAVPTSRGMPGTVQSGQAHLASSP 573
Query: 432 MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 491
SS +PG + P ++ P +P G ++V G A + S
Sbjct: 574 P-SSQAPGALQECPPTLAPGMTLAPVQG------TAHVVKGGA-------------TTSS 613
Query: 492 PVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMIN 551
PV A+ P F + S ++ P P ++ A +A+ ++ D + L + +
Sbjct: 614 PVVAQVPAAFYMQS---VHLPGKPQTL---AVKRKADSEEERDDVSTLGSMLPAKASPVA 667
Query: 552 KIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPP 611
+ K D K L + K + +++ TP P PP
Sbjct: 668 ESPKVMDEKSSLGE-----------------KAESVANVNANTPSSELVALTPAPSVPPP 710
Query: 612 T 612
T
Sbjct: 711 T 711
Score = 45.8 bits (107), Expect = 2e-04
Identities = 101/469 (21%), Positives = 163/469 (34%), Gaps = 60/469 (12%)
Query: 171 QQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQ---QQLQQQQQQQQHLIKLHHQ- 226
Q Q +L ++Q Q Q Q Q +A Q Q ++QQQ QL QQ I Q
Sbjct: 25 QIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQA 84
Query: 227 ---NQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPS 283
N QQQ Q A + L Q + Q + A Q + PP
Sbjct: 85 SSPNTSTTQQQTTTTQ--ASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPP- 141
Query: 284 QALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALP-GQMLYTQ 342
L Q QM+ +PQ + Q + + PL SQ +P G + Q
Sbjct: 142 --LNQSQAQMYL--------RPQLGNLLQVNRTL----GRNVPLASQLILMPNGAVAAVQ 187
Query: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFP 402
+ Q P V Q Q Q A P +Q T+ G
Sbjct: 188 QEVPSA------QSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGAS------ 235
Query: 403 PTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS 462
P +++S S ++ + + +QS LS G P SM P G
Sbjct: 236 PVSSLSQASSQALAVAQASSGATNQSL--NLSQAGGGSGNSIPGSMGPGGGGQAHGGL-G 292
Query: 463 SQPNSNVSSGPAPSPSSFLPSPSP--------QPSQSPVTARTPQNFSVPSPGPLNTPVN 514
P+S + G P + + P P Q SQ+ + + G N +N
Sbjct: 293 QLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMN 352
Query: 515 PSSVMSPAGS---------SQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSK 565
+ +PA S +Q + + + +Q+ +++ + +I + +++ +
Sbjct: 353 LTRTATPAPSQTLISSATYTQIQPHSLIQQQQQI--HLQQKQVVIQQQIAIHHQQQFQHR 410
Query: 566 MKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQ 614
LL T + + Q+ + ++ + P PP VPPT+Q
Sbjct: 411 QSQLLHTATH-LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQ 458
>gi|169164745 PREDICTED: similar to hCG2014450 [Homo sapiens]
Length = 297
Score = 123 bits (308), Expect = 8e-28
Identities = 61/90 (67%), Positives = 69/90 (76%), Gaps = 10/90 (11%)
Query: 633 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 682
+FNHSLY F+P + AIH PPIT APVVCTRK RLEDDE+QSI SVLQG V
Sbjct: 62 LFNHSLYCIFMPTLIAIHSPPITYIQLGWASRRAPVVCTRKHRLEDDEQQSISSVLQGLV 121
Query: 683 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 712
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|169163050 PREDICTED: hypothetical protein LOC100127989 [Homo
sapiens]
Length = 297
Score = 123 bits (308), Expect = 8e-28
Identities = 61/90 (67%), Positives = 69/90 (76%), Gaps = 10/90 (11%)
Query: 633 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 682
+FNHSLY F+P + AIH PPIT APVVCTRK RLEDDE+QSI SVLQG V
Sbjct: 62 LFNHSLYCIFMPTLIAIHSPPITYIQLGWASRRAPVVCTRKHRLEDDEQQSISSVLQGLV 121
Query: 683 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 712
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|169164311 PREDICTED: similar to hCG2014450 [Homo sapiens]
Length = 297
Score = 122 bits (305), Expect = 2e-27
Identities = 60/90 (66%), Positives = 69/90 (76%), Gaps = 10/90 (11%)
Query: 633 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 682
+FNHSLY F+P + AIH PPIT APVVCTRK RLEDDE+QSI S+LQG V
Sbjct: 62 LFNHSLYCIFMPTLIAIHSPPITYIQLGWASRRAPVVCTRKHRLEDDEQQSISSMLQGLV 121
Query: 683 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 712
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 113 bits (282), Expect = 8e-25
Identities = 82/164 (50%), Positives = 95/164 (57%), Gaps = 19/164 (11%)
Query: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-------QQQQQQQQQQQFQAQQSA 195
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ
Sbjct: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
Query: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQ 253
QQQ Q QQQQQ QQQQQQQQH K Q ++Q QQQQQQ Q AQ + QQQ Q Q
Sbjct: 172 QQQQQQ---QQQQQQQQQQQQQQHPGK---QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
Query: 254 QQQQQQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
Q QQQQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 269
Score = 108 bits (269), Expect = 3e-23
Identities = 85/190 (44%), Positives = 96/190 (50%), Gaps = 21/190 (11%)
Query: 140 SMAVVSTATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQQQ--QQQQFQAQQSAM 196
+M TPQ Q LQQ L QQ Q QQQQ LQQQQ Q+ ++QQ Q +
Sbjct: 92 AMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLL 151
Query: 197 QQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+ Q +Q ++QQQQQ
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQ 204
Query: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
QQQQQ A Q Q QQ +Q QQLQQ H Q PP P
Sbjct: 205 QQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQRQGLISIPPGQAALPV 253
Query: 317 QLPPQSQTQP 326
Q PQ+ P
Sbjct: 254 QSLPQAGLSP 263
Score = 106 bits (265), Expect = 7e-23
Identities = 100/254 (39%), Positives = 119/254 (46%), Gaps = 40/254 (15%)
Query: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ---QVALQQQ----- 163
GM +L + S G+ +SG ++ V Q Q LQ Q+ LQQQ
Sbjct: 19 GMSTLSSQLDAGSRDGR----SSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLK 74
Query: 164 -----QQQQQFQQQQQAAL--------QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQ 209
+Q+ Q A+ QQ QQ QQQ QQ A+ QQ QAV+ QQQQ
Sbjct: 75 SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ 134
Query: 210 LQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
LQ+ +QQ+Q HL L Q QQQ QQQQQQ Q Q Q QQQQQQQQQQQQQQQQ Q
Sbjct: 135 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQ 191
Query: 267 QPPIQQPPMQQPQPPPSQ------ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--L 318
P Q QQ Q Q QQL QM Q Q Q+ + P Q L
Sbjct: 192 HPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 251
Query: 319 PPQSQTQPLVSQAQ 332
P QS Q +S A+
Sbjct: 252 PVQSLPQAGLSPAE 265
Score = 31.2 bits (69), Expect = 3.9
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 364 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 422
Query: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
S + + + + Q P P P P+ Q PS + P S
Sbjct: 423 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 468
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 112 bits (280), Expect = 1e-24
Identities = 89/229 (38%), Positives = 103/229 (44%), Gaps = 13/229 (5%)
Query: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIK 222
QQ Q + +L QQQQQQQ Q QQ QQQ Q QQQQQ QQQQQQQQ I
Sbjct: 569 QQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQSSIS 625
Query: 223 LHHQNQQQ--IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQP 280
Q QQQ I QQQQ Q+ Q Q QQQQQQQQQQQQQQ + AQ QP ++ P P
Sbjct: 626 AQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLP 685
Query: 281 PPSQALPQQLQQMHHT----QHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336
+ L QQ+Q Q Q Q Q V QN P + P
Sbjct: 686 LQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
Query: 337 QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQM 385
Q L Q + Q + Q QQ Q A+ +AP Q+
Sbjct: 746 QSLLNQQ----LMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQI 790
Score = 103 bits (258), Expect = 5e-22
Identities = 129/448 (28%), Positives = 169/448 (37%), Gaps = 70/448 (15%)
Query: 71 NKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGP-GQSLGGMGSLGAMGQPMSLSGQP 129
N++ A + Q +AG P GP GQ S G Q S P
Sbjct: 442 NRQQHARMQQHQQQHQPTNWSALPSSAG---PSPGPFGQEKIPSPSFGQ--QTFSPQSSP 496
Query: 130 PPGTSGMAPHSMAVVS---TATPQTQLQLQQVALQQQQQQ--QQFQQQQQAALQQQQQQQ 184
PG +G + S + + A P Q V +QQ+ Q + F A++ +Q
Sbjct: 497 MPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNT 556
Query: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQL 244
+ F QQ +V+ Q + L H QQQ QQQQQQ Q+ Q
Sbjct: 557 KPL-FHFNSDQANQQMPSVLPSQNKPS-----------LLHYTQQQQQQQQQQQQQQQQQ 604
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ 304
Q QQQQQQQQQQQQQQQ ++ AQ Q Q S QQ QQ Q Q Q
Sbjct: 605 QQQQQQQQQQQQQQQQQSSISAQ---------QQQQQQSSISAQQQQQQQQQQQQQQQQQ 655
Query: 305 PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQP-PLKFVRAPMVVQQPPVQP-- 361
QQ Q QPS P AQ+LP Q L P PL+ +++QQ QP
Sbjct: 656 QQQQQQQQQQPSSQP-----------AQSLPSQPLLRSPLPLQ---QKLLLQQMQNQPIA 701
Query: 362 ----QVQQQQTAVQTAQAAQMVAPGVQ---MITEALAQGGMHIRARFPPTTAVSAIPSSS 414
QV QQQ Q + Q P G M+ + + +
Sbjct: 702 GMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQ----SLLNQQLMGKK 757
Query: 415 IPLGRQPMAQ-----VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 469
L RQ M Q + Q L +P Q+ S PPP + + QP +
Sbjct: 758 QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQY 817
Query: 470 SSGPAPSPSSFLPSPSPQPSQSPVTART 497
S G SS + S Q +PV+ T
Sbjct: 818 SGG-----SSTISLNSNQALANPVSTHT 840
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 112 bits (279), Expect = 2e-24
Identities = 75/158 (47%), Positives = 91/158 (57%), Gaps = 7/158 (4%)
Query: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQA 202
V+S Q LQ QQ + QQQQ Q+F ++QQ L Q QQQQQQ Q QQ QQQ Q
Sbjct: 20 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 79
Query: 203 VVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQ 262
QQQQQ QQQQQQQQ + + ++ QQQQQQ Q++A QL QQQ Q QQ QQQQ
Sbjct: 80 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 139
Query: 263 ---ALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
+LQ Q I PP Q P P + P ++QQ+
Sbjct: 140 HLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 177
Score = 107 bits (268), Expect = 3e-23
Identities = 85/189 (44%), Positives = 95/189 (50%), Gaps = 21/189 (11%)
Query: 141 MAVVSTATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQQQ--QQQQFQAQQSAMQ 197
M TPQ Q LQQ L QQ Q QQQQ LQQQQ Q+ ++QQ Q +Q
Sbjct: 1 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 60
Query: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
QQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+ Q +Q ++QQQQQQ
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQ 113
Query: 258 QQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ 317
QQQQ A Q Q QQ +Q QQLQQ H Q PP P Q
Sbjct: 114 QQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQRQGLISIPPGQAALPVQ 162
Query: 318 LPPQSQTQP 326
PQ+ P
Sbjct: 163 SLPQAGLSP 171
Score = 104 bits (260), Expect = 3e-22
Identities = 80/167 (47%), Positives = 89/167 (53%), Gaps = 15/167 (8%)
Query: 178 QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQLQQ---QQQQQQHLIKLHHQNQQQIQQ 233
QQ QQ QQQ QQ A+ QQ QAV+ QQQQLQ+ +QQ+Q HL L Q QQQ QQ
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ------ALP 287
QQQQ Q Q Q QQQQQQQQQQQQQQQQ Q P Q QQ Q Q
Sbjct: 70 QQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 126
Query: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--LPPQSQTQPLVSQAQ 332
QQL QM Q Q Q+ + P Q LP QS Q +S A+
Sbjct: 127 QQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 173
Score = 94.4 bits (233), Expect = 4e-19
Identities = 85/253 (33%), Positives = 107/253 (42%), Gaps = 36/253 (14%)
Query: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
QQ QQ QQ QQ QA++QQQQ + QQQQ Q K +QQ+QL +
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK----------KQQEQLH-LQL 58
Query: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP 303
LQ QQQQQQQQQQQQQQQQ Q Q QQ QQ QQ QQ H
Sbjct: 59 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----------QQQQQQQH-------- 100
Query: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363
P + Q Q Q Q Q LV Q Q L Q L Q L ++ ++ PP Q +
Sbjct: 101 -PGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 159
Query: 364 QQQ---QTAVQTAQAAQM---VAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPL 417
Q Q + A+ Q+ V M + GG+ + +T S +S P+
Sbjct: 160 PVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPI 219
Query: 418 GRQPMAQVSQSSL 430
+ S L
Sbjct: 220 THHSIVNGQSSVL 232
Score = 55.8 bits (133), Expect = 1e-07
Identities = 96/387 (24%), Positives = 144/387 (37%), Gaps = 42/387 (10%)
Query: 239 QRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI--QQPPMQQPQPPPSQALPQQLQQMHHT 296
Q I Q+QQ QQQ QQ Q LQ Q + QQ +Q+ + L QL Q
Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 64
Query: 297 QHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG-----QMLYTQPPLKFVRAP 351
Q Q Q QQ Q Q Q Q Q Q Q Q PG Q Q +
Sbjct: 65 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQHPGKQAKEQQQQQQQQQQLAAQQ 122
Query: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVA--PG-VQMITEALAQGGM---HIRARFPPTT 405
+V QQ +Q Q QQQ + + Q +++ PG + ++L Q G+ I+ + T
Sbjct: 123 LVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 182
Query: 406 AVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQP 465
V ++ + I G + + SS T ++ PP S GQ
Sbjct: 183 GVHSMEDNGIKHGGLDLTTNNSSST---------TSSNTSKASPPITHHSIVNGQ----- 228
Query: 466 NSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSP-GPLNTPVNPSSVMSPAGS 524
S+V S S SS + + + P S+ G +N + +
Sbjct: 229 -SSVLSARRDS-SSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRST 286
Query: 525 SQAEEQ-QYLDKLK-QLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPL 582
+Q Q Q + +L+ QLSK E L+ M+ + K K +L+ +T
Sbjct: 287 AQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVT-------- 338
Query: 583 KTLQKCEIALEKLKNDMAVPTPPPPPV 609
+ E + + L PT P P+
Sbjct: 339 MSKNMLETSPQSLPQTPTTPTAPVTPI 365
Score = 31.2 bits (69), Expect = 3.9
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 272 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 330
Query: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
S + + + + Q P P P P+ Q PS + P S
Sbjct: 331 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 376
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 112 bits (279), Expect = 2e-24
Identities = 78/164 (47%), Positives = 93/164 (56%), Gaps = 25/164 (15%)
Query: 143 VVSTATPQT----QLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
++ST TP + Q ++ A+ +QQQQQ QQQQQ QQQQQQQQQQQ Q QQ
Sbjct: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQ---QYHIRQQ 2082
Query: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Q Q +++QQQQ QQQQQQQQ Q QQQ QQQQQ QQ QQQQQQQ
Sbjct: 2083 QQQQILRQQQQQQQQQQQQQ-------QQQQQQQQQQQ----------QQHQQQQQQQAA 2125
Query: 259 QQQQALQAQPPIQQPPMQQ-PQPPPSQALPQQLQQMHHTQHHQP 301
Q Q+QP Q+ +QQ Q + AL +QLQQ QP
Sbjct: 2126 PPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
Score = 107 bits (266), Expect = 6e-23
Identities = 93/241 (38%), Positives = 110/241 (45%), Gaps = 38/241 (15%)
Query: 95 GAAGIGMPPR---GPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAP---HSMAVVSTAT 148
G AG +PP P QS + + L +P AP H + +
Sbjct: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
Query: 149 PQTQLQLQQVALQQQQQQQQFQQ--QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
QT Q ++ Q Q + A L +QQQQQQQQQ Q QQ QQQ QQ
Sbjct: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQ----QQQ 2073
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
QQQ +QQQQQ +++ Q QQQ QQQQQQ QQQQQQQQQQQ QQQQ QA
Sbjct: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQ---------QQQQQQQQQQQHQQQQQQQA 2124
Query: 267 QPPIQQPPMQQPQPPPSQALPQ-QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
PP QPQP Q+ PQ Q Q + TQ Q QQ Q Q +Q Q
Sbjct: 2125 APP-------QPQP---QSQPQFQRQGLQQTQ------QQQQTAALVRQLQQQLSNTQPQ 2168
Query: 326 P 326
P
Sbjct: 2169 P 2169
Score = 95.1 bits (235), Expect = 2e-19
Identities = 90/240 (37%), Positives = 100/240 (41%), Gaps = 40/240 (16%)
Query: 114 GSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQ--------- 164
G G M P S S QP T H + P LQ + QQ
Sbjct: 1958 GPAGTMVPP-SYSSQPYQST-----HPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLT 2011
Query: 165 QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLH 224
Q+F Q LQQ AQ + A++ +QQQ QQQQQQQQ
Sbjct: 2012 STQRFSHQ---TLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQ----- 2063
Query: 225 HQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ 284
QQQ QQQQQQ Q+ Q QQQQ +QQQQQQQQQ Q Q QQ QQ
Sbjct: 2064 ---QQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQ------- 2113
Query: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQAQALPGQMLYTQP 343
QQ QQ Q P PQPQ P Q Q Q Q QT LV Q Q Q+ TQP
Sbjct: 2114 ---QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQ---QLSNTQP 2167
Score = 47.8 bits (112), Expect = 4e-05
Identities = 66/267 (24%), Positives = 90/267 (33%), Gaps = 26/267 (9%)
Query: 193 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ 252
++++ +Q Q V Q Q+L+QQ QQ Q ++ Q Q+ + LQ Q
Sbjct: 1894 KTSVYRQQQPAVPQGQRLRQQLQQSQGMLG---------QSSVHQMTPSSSYGLQTSQGY 1944
Query: 253 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ 312
Q PP QP S + T+H Q P V Q
Sbjct: 1945 TPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGY---VHQ 2001
Query: 313 NQPSQLPPQSQTQPLVSQA-QALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ 371
P+ + TQ Q Q P M+ T P+ V+ + P+ QQQQ Q
Sbjct: 2002 QAPTYGHGLTSTQRFSHQTLQQTP--MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQ 2059
Query: 372 TAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLP 431
Q Q Q + Q HIR + I +Q Q Q
Sbjct: 2060 QQQQQQ------QQQQQQQQQQQYHIRQQ-----QQQQILRQQQQQQQQQQQQQQQQQQQ 2108
Query: 432 MLSSPSPGQQVQTPQSMPPPPQPSPQP 458
QQ Q Q+ PP PQP QP
Sbjct: 2109 QQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
Score = 47.0 bits (110), Expect = 7e-05
Identities = 65/266 (24%), Positives = 90/266 (33%), Gaps = 54/266 (20%)
Query: 169 FQQQQQAALQQQQQQQQQQQFQAQ--QSAMQQQ----------------FQAVVQQQQ-- 208
++QQQ A Q Q+ +QQ QQ Q QS++ Q + + V QQ
Sbjct: 1898 YRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT 1957
Query: 209 ---------QLQQQQQQQQH------LIKLHHQNQQQ----IQQQ--------------- 234
Q Q H L+ QQ+ + QQ
Sbjct: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
Query: 235 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH 294
Q LQ+ + Q Q + A+ + QQ QQ Q Q QQ QQ +
Sbjct: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
Query: 295 HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV 354
H + Q +Q Q Q Q Q Q Q Q Q Q PP ++
Sbjct: 2078 HIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQF 2137
Query: 355 QQPPVQPQVQQQQTAVQTAQAAQMVA 380
Q+ +Q QQQQTA Q Q ++
Sbjct: 2138 QRQGLQQTQQQQQTAALVRQLQQQLS 2163
Score = 41.6 bits (96), Expect = 0.003
Identities = 57/247 (23%), Positives = 79/247 (31%), Gaps = 26/247 (10%)
Query: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQH-----HQP 301
+QQQ Q Q+ +QQ Q+Q + Q + Q P S L + H H
Sbjct: 1899 RQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTG 1958
Query: 302 PPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQP 361
P PP +QP Q S LV + L Q P +V QQ P
Sbjct: 1959 PAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQ------QRPSGYVH-----QQAPTYG 2007
Query: 362 Q--VQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGR 419
Q+ + QT Q M++ M + + Q G+ A P +
Sbjct: 2008 HGLTSTQRFSHQTLQQTPMISTMTPMSAQGV-QAGVRSTAILPEQQQQQQQQQQQQQQQQ 2066
Query: 420 QPMAQ-------VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 472
Q Q + Q + QQ Q Q Q Q Q Q ++
Sbjct: 2067 QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAP 2126
Query: 473 PAPSPSS 479
P P P S
Sbjct: 2127 PQPQPQS 2133
Score = 32.7 bits (73), Expect = 1.3
Identities = 26/64 (40%), Positives = 27/64 (42%), Gaps = 19/64 (29%)
Query: 150 QTQLQLQQVALQQQQQQ-------------------QQFQQQQQAALQQQQQQQQQQQFQ 190
Q Q Q QQ QQQQQQ QQ QQQQQ A +Q QQQ Q
Sbjct: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
Query: 191 AQQS 194
Q S
Sbjct: 2167 PQPS 2170
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 111 bits (278), Expect = 2e-24
Identities = 78/160 (48%), Positives = 90/160 (56%), Gaps = 11/160 (6%)
Query: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-----QQQQQQQQQQQFQAQQSAMQ 197
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ Q
Sbjct: 137 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 196
Query: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
QQ Q QQQQQ QQQQQQQQ + QQQ QQQQQQL + QQ Q QQ QQ
Sbjct: 197 QQQQQ--QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 254
Query: 258 QQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
QQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 255 QQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 294
Score = 111 bits (277), Expect = 3e-24
Identities = 90/206 (43%), Positives = 105/206 (50%), Gaps = 23/206 (11%)
Query: 126 SGQPPPGTSGMAPHSMAVVS--TATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQ 182
SG P + P S+A+++ TPQ Q LQQ L QQ Q QQQQ LQQQQ
Sbjct: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL 160
Query: 183 QQ--QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Q+ ++QQ Q +QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+
Sbjct: 161 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQ 213
Query: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Q +Q ++QQQQQQQQQQ A Q Q QQ +Q QQLQQ H Q
Sbjct: 214 QQQHPGKQAKEQQQQQQQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQ 262
Query: 301 PPPQPQQPPVAQNQPSQLPPQSQTQP 326
PP P Q PQ+ P
Sbjct: 263 RQGLISIPPGQAALPVQSLPQAGLSP 288
Score = 104 bits (260), Expect = 3e-22
Identities = 80/167 (47%), Positives = 89/167 (53%), Gaps = 15/167 (8%)
Query: 178 QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQLQQ---QQQQQQHLIKLHHQNQQQIQQ 233
QQ QQ QQQ QQ A+ QQ QAV+ QQQQLQ+ +QQ+Q HL L Q QQQ QQ
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ------ALP 287
QQQQ Q Q Q QQQQQQQQQQQQQQQQ Q P Q QQ Q Q
Sbjct: 187 QQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
Query: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--LPPQSQTQPLVSQAQ 332
QQL QM Q Q Q+ + P Q LP QS Q +S A+
Sbjct: 244 QQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
Score = 94.4 bits (233), Expect = 4e-19
Identities = 85/253 (33%), Positives = 107/253 (42%), Gaps = 36/253 (14%)
Query: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
QQ QQ QQ QQ QA++QQQQ + QQQQ Q K +QQ+QL +
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK----------KQQEQLH-LQL 175
Query: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP 303
LQ QQQQQQQQQQQQQQQQ Q Q QQ QQ QQ QQ H
Sbjct: 176 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----------QQQQQQQH-------- 217
Query: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363
P + Q Q Q Q Q LV Q Q L Q L Q L ++ ++ PP Q +
Sbjct: 218 -PGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 276
Query: 364 QQQ---QTAVQTAQAAQM---VAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPL 417
Q Q + A+ Q+ V M + GG+ + +T S +S P+
Sbjct: 277 PVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPI 336
Query: 418 GRQPMAQVSQSSL 430
+ S L
Sbjct: 337 THHSIVNGQSSVL 349
Score = 63.5 bits (153), Expect = 7e-10
Identities = 113/475 (23%), Positives = 175/475 (36%), Gaps = 48/475 (10%)
Query: 151 TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
T ++ V L QQQQ Q +Q LQQQ + + +Q +Q+ + + + +
Sbjct: 40 TSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQE---LLPETKLCI 96
Query: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
H H+ + Q I Q+QQ QQQ QQ Q LQ Q +
Sbjct: 97 CGHSSGDGHP---HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAV 153
Query: 271 --QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
QQ +Q+ + L QL Q Q Q Q QQ Q Q Q Q Q Q
Sbjct: 154 MLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-- 211
Query: 329 SQAQALPG-----QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVA--P 381
Q Q PG Q Q + +V QQ +Q Q QQQ + + Q +++ P
Sbjct: 212 QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPP 271
Query: 382 G-VQMITEALAQGGM---HIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPS 437
G + ++L Q G+ I+ + T V ++ + I G + + SS
Sbjct: 272 GQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSST------- 324
Query: 438 PGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 497
T ++ PP S GQ S+V S S SS + + +
Sbjct: 325 --TSSNTSKASPPITHHSIVNGQ------SSVLSARRDS-SSHEETGASHTLYGHGVCKW 375
Query: 498 PQNFSVPSP-GPLNTPVNPSSVMSPAGSSQAEEQ-QYLDKLK-QLSKYIEPLRRMINKID 554
P S+ G +N + ++Q Q Q + +L+ QLSK E L+ M+ +
Sbjct: 376 PGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLH 435
Query: 555 KNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPV 609
K K +L+ +T + E + + L PT P P+
Sbjct: 436 MRPSEPKPSPKPLNLVSSVT--------MSKNMLETSPQSLPQTPTTPTAPVTPI 482
Score = 31.2 bits (69), Expect = 3.9
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 389 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 447
Query: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
S + + + + Q P P P P+ Q PS + P S
Sbjct: 448 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 493
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 109 bits (273), Expect = 9e-24
Identities = 90/208 (43%), Positives = 98/208 (47%), Gaps = 25/208 (12%)
Query: 148 TPQTQLQLQQVALQQQQQQQ---QFQQQQQAALQQQQQQQQQQQFQAQQ------SAMQQ 198
TP+T + QQ QQQQQQ Q QQ LQQQQQQQ QQ QQ QQ
Sbjct: 395 TPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ 454
Query: 199 QFQAVVQQ--QQQLQQQQQQQQHLIKLHHQNQQ--QIQQQ---QQQLQRIAQLQLQQQQQ 251
Q QA Q QQQLQ QQQ +LH QQ QQQ QQQ ++ Q QLQQQQ
Sbjct: 455 QQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL 514
Query: 252 QQQQQQ-----QQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306
Q QQQ QQQQQ +Q Q + QQ Q SQ P Q QH PP QP
Sbjct: 515 AQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPP 574
Query: 307 QPPVAQNQPSQLPPQSQTQPLVSQAQAL 334
Q Q Q Q PP Q L A+
Sbjct: 575 Q----QQQQQQPPPSPQQHQLFGHDPAV 598
Score = 91.7 bits (226), Expect = 2e-18
Identities = 89/260 (34%), Positives = 109/260 (41%), Gaps = 14/260 (5%)
Query: 155 LQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQ 214
LQ ++ + +QQ QQ Q + + +QQQ QA QQQQQ
Sbjct: 360 LQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQ-QQQQQHPVLH 418
Query: 215 QQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL-----QAQPP 269
Q Q +++L Q QQQI QQ Q QQQQQQQ Q QQ L Q PP
Sbjct: 419 LQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPP 478
Query: 270 IQ-QPPMQQPQPPPSQ-ALPQQLQQM--HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
Q P QQ QP Q AL QQ Q+ H Q Q QQ + Q Q Q Q Q Q
Sbjct: 479 QQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQ 538
Query: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ-PQVQQQQTAVQTAQAAQMVA--PG 382
+ Q Q Q T P L + Q PP Q PQ QQQQ + Q Q+ P
Sbjct: 539 RMHQQQQQQQMQS-QTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPA 597
Query: 383 VQMITEALAQGGMHIRARFP 402
V++ E G + A +P
Sbjct: 598 VEIPEEGFLLGCVFAIADYP 617
Score = 91.3 bits (225), Expect = 3e-18
Identities = 84/238 (35%), Positives = 104/238 (43%), Gaps = 16/238 (6%)
Query: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS--AM 196
H + +S T + Q+ Q + + QQQQQ Q QQ +
Sbjct: 358 HILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVL 417
Query: 197 QQQFQAVVQQQQQLQQQQQQQQHLIKLHHQ-NQQQIQQQQQQLQRIAQLQLQQQQQ---- 251
Q Q ++Q QQQ QQQ QQ + + H +QQQ QQQQ + +Q QLQ QQ
Sbjct: 418 HLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHP 477
Query: 252 -QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHH--TQHHQPPPQPQQP 308
QQ + QQQ Q Q Q +QQ Q Q Q QLQQ H Q Q Q QQ
Sbjct: 478 PQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQL 537
Query: 309 PVAQNQPSQLPPQSQTQPLVSQ-AQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Q Q QSQT P +SQ +QAL Q+ QPP + QQPP PQ Q
Sbjct: 538 QRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ-----QQQQQPPPSPQQHQ 590
Score = 79.0 bits (193), Expect = 2e-14
Identities = 83/295 (28%), Positives = 101/295 (34%), Gaps = 68/295 (23%)
Query: 180 QQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQ 239
+QQ QQ +A+ V + LQQQQQ QQ QQQQ +
Sbjct: 371 EQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQ-------------QQQQHPVL 417
Query: 240 RIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH 299
+ Q+ Q QQQQQQQ QQ Q P Q QQ Q P Q QQLQ H
Sbjct: 418 HLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLH- 476
Query: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV 359
PPQ P Q QP Q Q Q Q L Q L
Sbjct: 477 --PPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL-------------------- 514
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGR 419
Q+QQQ + +Q Q Q+ +Q + + +
Sbjct: 515 -AQLQQQHSLLQQQQQQQIQQQQLQRMHQ------------------------------Q 543
Query: 420 QPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA 474
Q Q+ + P LS S Q Q P PP Q QP PS Q + PA
Sbjct: 544 QQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQP-PPSPQQHQLFGHDPA 597
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 105 bits (261), Expect = 2e-22
Identities = 139/480 (28%), Positives = 182/480 (37%), Gaps = 54/480 (11%)
Query: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143
+GGP G AG G M + G + + A G S P PG+SG +A
Sbjct: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375
Query: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200
TPQ + Q+ + Q + QQQ QQ Q Q+ Q++
Sbjct: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430
Query: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260
+Q + Q I + Q QQ Q Q QQQQ QQ
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
Query: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319
Q AQP QQ P QP P + P QQ H Q P P P Q Q P P
Sbjct: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q
Sbjct: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597
Query: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
P + L+Q +A P+ S + L Q SSLP LS
Sbjct: 598 PP-----PQELSQDSFGSQASSAPSMTSSKGGQEDMNLS----LQSRPSSLPDLSGSIDD 648
Query: 440 QQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNVSSGP-APSPSSFLP---SPSPQPSQSPVT 494
+ T ++ P S G SSQ SN + P +P S LP PSP P SP +
Sbjct: 649 LPMGTEGALSPGVSTS---GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPAS 705
Query: 495 ---ARTPQNFSVPSPGPLNTPVNPS----SVMSPA--GSSQAEEQQYLDKLKQLSKYIEP 545
+R+ PG P PS S+M P+ SS A+++ Y+ + Q+ +Y P
Sbjct: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765
Score = 61.2 bits (147), Expect = 4e-09
Identities = 111/416 (26%), Positives = 140/416 (33%), Gaps = 67/416 (16%)
Query: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140
P ++ G + G+ + P G G GQ + Q P P+S
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
Query: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197
S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q
Sbjct: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
Query: 198 QQFQAVVQQQQ-QLQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253
Q Q+ Q Q Q QQQ QQ Q Q Q QQ Q+ A Q + Q+
Sbjct: 543 QHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602
Query: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP-------PPQPQ 306
Q QA A Q+ Q+ P L + + P P
Sbjct: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
Query: 307 QPPVAQNQPSQL-PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
++ +Q Q P QS P +T P L +R P P P
Sbjct: 663 TSGISSSQGEQSNPAQSPFSP-------------HTSPHLPGIRGPS--PSPVGSPASVA 707
Query: 366 QQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAI--PS---SSIPLGRQ 420
Q + + AA PG QM PP+ +I PS SSI R
Sbjct: 708 QSRSGPLSPAA---VPGNQMPPR-------------PPSGQSDSIMHPSMNQSSIAQDRG 751
Query: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP---QPGQPSSQPNSNVSSGP 473
M + Q +P SSP PG + P QPS G S Q NS S GP
Sbjct: 752 YMQRNPQ--MPQYSSPQPGSALS-------PRQPSGGQIHTGMGSYQQNSMGSYGP 798
Score = 58.9 bits (141), Expect = 2e-08
Identities = 102/400 (25%), Positives = 138/400 (34%), Gaps = 74/400 (18%)
Query: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQ---HHQPPPQ---- 304
QQQQQQQQ+ + Q Q P P P + QQ QQ + + PP +
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEG 1386
Query: 305 -----PQQPPVAQNQPSQLPPQSQTQPLVSQ--AQALPGQMLYTQPPLKF--VRAPMVVQ 355
P Q Q QLPP +Q QP Q AQ P Q +Y Q + +
Sbjct: 1387 EMYSVPYSTGQGQPQQQQLPP-AQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATER 1445
Query: 356 QPPVQPQVQ------------QQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPP 403
+P PQ Q T Q QM+ +Q E QG M
Sbjct: 1446 RPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMT 1505
Query: 404 TTAVSAIPSSSIPLG--------RQPMAQVSQSSLPMLSSPSPG-QQVQTPQSMPPPPQP 454
+ + S P G M Q + S PS G +Q S P PP
Sbjct: 1506 YNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMT 1565
Query: 455 SPQPGQ----PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV--------TARTPQNFS 502
P P PS Q + S PAP P S PS+SP A P S
Sbjct: 1566 RPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTS--PSKSPFLHSGMKMQKAGPPVPAS 1623
Query: 503 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYI---EPLRRMIN-------- 551
+P P+ P+ + P GS +A + + + K I E R M++
Sbjct: 1624 HIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAE 1683
Query: 552 -----------KIDKNEDRKKDLSKMKSLLDILTDPSKRC 580
D N +LS++ LL++L + +RC
Sbjct: 1684 STWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRC 1723
Score = 30.4 bits (67), Expect = 6.7
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 446 QSMPPPPQP-----SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTAR---T 497
+S PPP P SP+ G P S + S P PS S+ S S +Q A
Sbjct: 219 RSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG 278
Query: 498 PQNFSVPSPGPLNTPVNPSSVMSPAGS 524
P +P P TP + SP+ +
Sbjct: 279 PSAAGGGTPQPTATPTLNQLLTSPSSA 305
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 105 bits (261), Expect = 2e-22
Identities = 139/480 (28%), Positives = 182/480 (37%), Gaps = 54/480 (11%)
Query: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143
+GGP G AG G M + G + + A G S P PG+SG +A
Sbjct: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375
Query: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200
TPQ + Q+ + Q + QQQ QQ Q Q+ Q++
Sbjct: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430
Query: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260
+Q + Q I + Q QQ Q Q QQQQ QQ
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
Query: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319
Q AQP QQ P QP P + P QQ H Q P P P Q Q P P
Sbjct: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q
Sbjct: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597
Query: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
P + L+Q +A P+ S + L Q SSLP LS
Sbjct: 598 PP-----PQELSQDSFGSQASSAPSMTSSKGGQEDMNLS----LQSRPSSLPDLSGSIDD 648
Query: 440 QQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNVSSGP-APSPSSFLP---SPSPQPSQSPVT 494
+ T ++ P S G SSQ SN + P +P S LP PSP P SP +
Sbjct: 649 LPMGTEGALSPGVSTS---GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPAS 705
Query: 495 ---ARTPQNFSVPSPGPLNTPVNPS----SVMSPA--GSSQAEEQQYLDKLKQLSKYIEP 545
+R+ PG P PS S+M P+ SS A+++ Y+ + Q+ +Y P
Sbjct: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765
Score = 61.2 bits (147), Expect = 4e-09
Identities = 111/416 (26%), Positives = 140/416 (33%), Gaps = 67/416 (16%)
Query: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140
P ++ G + G+ + P G G GQ + Q P P+S
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
Query: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197
S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q
Sbjct: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
Query: 198 QQFQAVVQQQQ-QLQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253
Q Q+ Q Q Q QQQ QQ Q Q Q QQ Q+ A Q + Q+
Sbjct: 543 QHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602
Query: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP-------PPQPQ 306
Q QA A Q+ Q+ P L + + P P
Sbjct: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
Query: 307 QPPVAQNQPSQL-PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
++ +Q Q P QS P +T P L +R P P P
Sbjct: 663 TSGISSSQGEQSNPAQSPFSP-------------HTSPHLPGIRGPS--PSPVGSPASVA 707
Query: 366 QQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAI--PS---SSIPLGRQ 420
Q + + AA PG QM PP+ +I PS SSI R
Sbjct: 708 QSRSGPLSPAA---VPGNQMPPR-------------PPSGQSDSIMHPSMNQSSIAQDRG 751
Query: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP---QPGQPSSQPNSNVSSGP 473
M + Q +P SSP PG + P QPS G S Q NS S GP
Sbjct: 752 YMQRNPQ--MPQYSSPQPGSALS-------PRQPSGGQIHTGMGSYQQNSMGSYGP 798
Score = 37.0 bits (84), Expect = 0.071
Identities = 104/501 (20%), Positives = 175/501 (34%), Gaps = 71/501 (14%)
Query: 71 NKKSQASVSDPMNALQSLTGGPAA-------GAAGIGMPPRGPG-QSLGGMGSLGAMGQP 122
N+K+Q + A S+ P G G G PP G G S+ GM + G P
Sbjct: 891 NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTG-PPYGQGINSMAGM--INPQGPP 947
Query: 123 MSLSGQPPPGTSGMA--PHSMAVVSTA-TPQTQLQLQQVALQQQQQQQQFQQQQQAALQQ 179
S+ G ++GMA P M + TP T++ + + + + + + +
Sbjct: 948 YSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSK-KSSSSTTTNE 1006
Query: 180 QQQQQQQQQFQAQQSAMQQQFQAVVQQQQQ----LQQQQQQQQHLIKLHHQNQQ-----Q 230
+ + + + ++ ++ A +++ L ++ L +L+ ++ Q
Sbjct: 1007 KITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQ 1066
Query: 231 IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA---------QPPIQ---------- 271
+ + ++ + L + ++Q Q L A PP
Sbjct: 1067 VNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKS 1126
Query: 272 QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQ 330
QP +Q P P S ++ Q Q T +PP + P SQ+PP P +S+
Sbjct: 1127 QPKIQPPSPAGSGSM-QGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPL----PGMSR 1181
Query: 331 AQALPGQMLYTQ-PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ-------AAQMVAPG 382
+ ++ Q + F + + P QP + + + + APG
Sbjct: 1182 SNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG 1241
Query: 383 VQ--MITEALAQGGM---HIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPS 437
M + GGM + RA P V+ P P G ++ + + S
Sbjct: 1242 SDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMS 1301
Query: 438 PGQQVQTPQSMPPPPQ-----PSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 492
G P MP P PS P Q Q S + PS SP PSQ
Sbjct: 1302 TG--APQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQ- 1358
Query: 493 VTARTPQNFSVPSPGPLNTPV 513
T Q V SP PL P+
Sbjct: 1359 -TTMYQQQQQVSSPAPLPRPM 1378
Score = 36.2 bits (82), Expect = 0.12
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA 311
QQQQQQQQ+ + Q Q P P P + QQ QQ+ P P P+
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQV-----SSPAPLPR----- 1376
Query: 312 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR-APMVVQQPPVQPQVQQQQTAV 370
P +++T P S +M PP+ AP VQ P ++ + +V
Sbjct: 1377 -------PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSV 1429
Query: 371 QTAQ 374
+ Q
Sbjct: 1430 EATQ 1433
Score = 35.8 bits (81), Expect = 0.16
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 21/121 (17%)
Query: 230 QIQQQQQQLQRIAQLQLQQQQ-------QQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Q QQQQQQ Q Q QQ QQQQ + + P+ +P + P
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSK 1386
Query: 283 SQALPQQLQQMHHTQHHQPP-------PQPQQPPVAQNQPSQLPPQS--QTQPLVSQAQA 333
S L ++ Q PP P P QPP+ + + PP S TQP++ Q +
Sbjct: 1387 SPFLHSGMKM----QKAGPPVPASHIAPAPVQPPMIRRDIT-FPPGSVEATQPVLKQRRR 1441
Query: 334 L 334
L
Sbjct: 1442 L 1442
Score = 32.0 bits (71), Expect = 2.3
Identities = 36/143 (25%), Positives = 52/143 (36%), Gaps = 10/143 (6%)
Query: 67 RDIHNKKSQASVSDP-MNALQSLTGGPA-----AGAAGIGMPPRGPGQSLGGMGSLGAMG 120
+D + +A SDP M++ Q GG A G+G GP Q G +
Sbjct: 1230 KDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR 1289
Query: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
+ + T P+ M + P + + QQQQQQQ +
Sbjct: 1290 TEPGIGPEGNMSTGAPQPNLMP----SNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345
Query: 181 QQQQQQQQFQAQQSAMQQQFQAV 203
Q F +QQ+ M QQ Q V
Sbjct: 1346 QGTPSGSPFPSQQTTMYQQQQQV 1368
Score = 30.8 bits (68), Expect = 5.1
Identities = 57/233 (24%), Positives = 77/233 (33%), Gaps = 53/233 (22%)
Query: 393 GGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLS-SPSPGQQVQ-------- 443
GG + R R P S+ P QP S M S S P QQ Q
Sbjct: 1282 GGPYDRVRTEPGIGPEGNMSTGAP---QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDS 1338
Query: 444 ---------TPQSMPPPPQPSPQPGQPSSQPNSNVSS-GPAPSPSSFLPSPSPQP----S 489
TP P P Q + Q VSS P P P SPS P
Sbjct: 1339 YGNQFSTQGTPSGSPFPSQQTTM-----YQQQQQVSSPAPLPRPMENRTSPSKSPFLHSG 1393
Query: 490 QSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYI---EPL 546
A P S +P P+ P+ + P GS +A + + + K I E
Sbjct: 1394 MKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAW 1453
Query: 547 RRMIN-------------------KIDKNEDRKKDLSKMKSLLDILTDPSKRC 580
R M++ D N +LS++ LL++L + +RC
Sbjct: 1454 RVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRC 1506
Score = 30.4 bits (67), Expect = 6.7
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 446 QSMPPPPQP-----SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTAR---T 497
+S PPP P SP+ G P S + S P PS S+ S S +Q A
Sbjct: 219 RSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG 278
Query: 498 PQNFSVPSPGPLNTPVNPSSVMSPAGS 524
P +P P TP + SP+ +
Sbjct: 279 PSAAGGGTPQPTATPTLNQLLTSPSSA 305
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 100 bits (248), Expect = 7e-21
Identities = 93/248 (37%), Positives = 112/248 (45%), Gaps = 39/248 (15%)
Query: 97 AGIGMPPRGPGQSLGGMGSLGAMGQPMSLS--GQPPPGTSGMAPHS-------------- 140
A + PP+ G S G L ++ QP + QP P T P +
Sbjct: 394 ATVQPPPQAAGSS-NQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQG 452
Query: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQ--QQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
+ + ATPQ Q QQ+ L+QQQQQQQ QQQ A QQQQ Q QQFQA A QQ
Sbjct: 453 LPAQAQATPQHQ---QQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ 509
Query: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
A Q + Q QQ L++ +Q QQQ QQQQQQ Q L QQ QQ QQ
Sbjct: 510 PAIA----QFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQ 565
Query: 259 QQQQALQAQPPIQQPPMQQPQPPPSQ--ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP- 315
+ A QP Q P PQP P+Q A+ ++Q QP Q PP Q Q
Sbjct: 566 KPTMAAGQQP--QPQPAAAPQPAPAQEPAIQAPVRQ-------QPKVQTTPPPAVQGQKV 616
Query: 316 -SQLPPQS 322
S PP S
Sbjct: 617 GSLTPPSS 624
Score = 70.9 bits (172), Expect = 4e-12
Identities = 83/288 (28%), Positives = 108/288 (37%), Gaps = 38/288 (13%)
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP--IQQPPMQQPQPPPSQALPQQLQ 291
Q Q I +Q +++ Q Q A + P + P +PQ PPSQ LPQ
Sbjct: 374 QTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQ--- 430
Query: 292 QMHHTQHHQP--PPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
TQ QP PP PQQ P Q Q LP Q+Q P Q L Q QPP
Sbjct: 431 ----TQAKQPQAPPTPQQTPSTQAQG--LPAQAQATPQHQQQLFLKQQQQQQQPP----- 479
Query: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSA 409
QQ P QQQQ Q QA V P Q A+AQ FP + +
Sbjct: 480 ---PAQQQPAGTFYQQQQAQTQQFQA---VHPATQQ--PAIAQ--------FPVVSQGGS 523
Query: 410 IPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 469
+Q Q Q L++ QQ+ T Q+ +P+ GQ QP
Sbjct: 524 QQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQ-KPTMAAGQ---QPQPQP 579
Query: 470 SSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 517
++ P P+P+ +P Q V P G L P +P +
Sbjct: 580 AAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKT 627
Score = 64.7 bits (156), Expect = 3e-10
Identities = 113/395 (28%), Positives = 144/395 (36%), Gaps = 86/395 (21%)
Query: 148 TPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ- 206
T +T + +Q Q Q Q AL +++ Q QA S+ Q A V Q
Sbjct: 359 TTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQP 418
Query: 207 ------QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ--QQQQQQ 258
Q L Q Q +Q + QQ Q Q L AQ Q QQQ +QQQQQ
Sbjct: 419 KPQAPPSQPLPQTQAKQP---QAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQ 475
Query: 259 QQQQALQAQPPIQQPP---MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP 315
QQ PP QQ P Q Q QA QQ Q +H P QQP +AQ
Sbjct: 476 QQ------PPPAQQQPAGTFYQQQ----QAQTQQFQAVH--------PATQQPAIAQ--- 514
Query: 316 SQLPPQSQTQPLVSQ--AQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA 373
P+VSQ +Q Q Y Q QQ Q Q QQ TA+
Sbjct: 515 ---------FPVVSQGGSQQQLMQNFYQQQ-----------QQQQQQQQQQQLATALHQQ 554
Query: 374 QAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPML 433
Q A Q T A Q A P A + P+ P+ +QP Q
Sbjct: 555 QLMTQQAALQQKPTMAAGQQPQPQPAA-APQPAPAQEPAIQAPVRQQPKVQ--------- 604
Query: 434 SSPSPGQQVQTPQSMPPPPQPSPQP----------------GQPSSQPNSNVSSGPAPSP 477
++P P Q Q S+ PP P Q G P+S+ + + A +
Sbjct: 605 TTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEAS 664
Query: 478 SSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTP 512
+ S + PS SP T++ QN PS G P
Sbjct: 665 LNKSKSATTTPSGSPRTSQ--QNVYNPSEGSTWNP 697
Score = 38.9 bits (89), Expect = 0.019
Identities = 38/152 (25%), Positives = 53/152 (34%), Gaps = 5/152 (3%)
Query: 397 IRARFP-PTTAVSAIPSSSIPLGR--QPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQ 453
I A+ P P A A + P R P+ S P P GQ P +P P
Sbjct: 329 IPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPR-QRPKAGQTQPNPGILPIQPA 387
Query: 454 PSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPV 513
+P+ P S P + +P P PQ S +T P P TP
Sbjct: 388 LTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPS 447
Query: 514 NPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEP 545
+ + + + QQ L LKQ + +P
Sbjct: 448 TQAQGLPAQAQATPQHQQQL-FLKQQQQQQQP 478
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 99.4 bits (246), Expect = 1e-20
Identities = 72/155 (46%), Positives = 83/155 (53%), Gaps = 24/155 (15%)
Query: 147 ATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
+ P TQ+ ++Q QQ Q Q QQQQQ QQQQQ QQ QQ Q QQ M QQ
Sbjct: 421 SAPSTQVS---PSVQTQQHQMQLQQQQQ---QQQQQMQQMQQQQLQQHQMHQQI------ 468
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL-QRIAQLQLQQQQQQQQQQQQQQQQALQ 265
QQQ QQQH H QQ +QQQQQ L Q+I Q QLQQQ QQ+ Q QQ Q Q
Sbjct: 469 -----QQQMQQQH---FQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQ 520
Query: 266 AQP-PIQQPPM--QQPQPPPSQALPQQLQQMHHTQ 297
+QP P Q P+ Q P P+ PQ Q H +Q
Sbjct: 521 SQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQ 555
Score = 97.1 bits (240), Expect = 6e-20
Identities = 73/163 (44%), Positives = 81/163 (49%), Gaps = 19/163 (11%)
Query: 135 GMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS 194
G AP + S T Q Q+QLQQ QQQQQ QQ QQQQ Q QQ QQQ Q Q Q
Sbjct: 420 GSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQH 479
Query: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
MQQ Q QQQQ LQQQ NQQQ+QQQ QQ ++ QLQ Q Q Q
Sbjct: 480 HMQQHLQ---QQQQHLQQQ------------INQQQLQQQLQQRLQLQQLQ-HMQHQSQP 523
Query: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQ 297
+Q A Q PI P + PQ P SQ Q+Q TQ
Sbjct: 524 SPRQHSPVASQITSPI--PAIGSPQ-PASQQHQSQIQSQTQTQ 563
Score = 89.4 bits (220), Expect = 1e-17
Identities = 65/160 (40%), Positives = 73/160 (45%), Gaps = 28/160 (17%)
Query: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Q QQ Q Q QQ QQQ QQQQQ+QQ QQQQ ++H Q QQQ+QQQ Q
Sbjct: 432 QTQQHQMQLQQ---QQQ-----QQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ 483
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPP 302
LQ QQQ QQQ QQQ QQ LQ + QLQQ+ H QH P
Sbjct: 484 HLQQQQQHLQQQINQQQLQQQLQQR--------------------LQLQQLQHMQHQSQP 523
Query: 303 PQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Q PVA S +P QP Q Q+ TQ
Sbjct: 524 SPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 563
Score = 63.2 bits (152), Expect = 9e-10
Identities = 55/151 (36%), Positives = 67/151 (44%), Gaps = 16/151 (10%)
Query: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
Q QQ Q QLQ QQQQQQQQQ QQ QQQ LQ QQ Q Q + Q
Sbjct: 432 QTQQHQMQLQ-------QQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH 484
Query: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
LQQ QH Q QQ Q Q Q Q Q + Q+Q P Q P +
Sbjct: 485 LQQQQ--QHLQQQINQQQ---LQQQLQQRLQLQQLQHMQHQSQPSPRQ---HSPVASQIT 536
Query: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVA 380
+P+ P QP QQ Q+ +Q+ Q+++
Sbjct: 537 SPIPAIGSP-QPASQQHQSQIQSQTQTQVLS 566
Score = 43.1 bits (100), Expect = 0.001
Identities = 100/482 (20%), Positives = 161/482 (33%), Gaps = 71/482 (14%)
Query: 6 QETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIH 65
Q D S + LV Q GV HS +SH + +D SL+ R I+H
Sbjct: 104 QSLDLPSITISRNLVEQ-------DGVLHSSGLHMDQSHTQVSQYRQDP--SLIMRSIVH 154
Query: 66 FRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRG---PGQSLGGMGSLGAMGQP 122
D A+ S M Q T + +A +G+ G P S S A P
Sbjct: 155 MTD-------AARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSP 207
Query: 123 MSLSGQ----------------PPPGTSGMAPHSMAVVSTATPQTQLQLQ-------QVA 159
S + P G P PQ + Q A
Sbjct: 208 SSSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAA 267
Query: 160 LQQQQQQQQFQQQQQ--AALQQQQQQQQQQQFQAQQSAMQQQF-QAVVQQQQQLQQQQQQ 216
++ Q F + + A++ ++Q+Q ++ + A ++++ +A+ + L +
Sbjct: 268 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAA 327
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQ---QQQQQQQQQQQQQALQAQPPIQQP 273
+ + QQ + + L Q Q QQ +++ +P +
Sbjct: 328 ESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRL 387
Query: 274 PMQQ-------PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQP 326
PM Q PS + M T P Q P Q Q Q+ Q Q Q
Sbjct: 388 PMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAP-STQVSPSVQTQQHQMQLQQQQQQ 446
Query: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQ--QPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
Q Q + Q L + ++ M Q Q +Q +QQQQ +Q Q + +Q
Sbjct: 447 QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 506
Query: 385 MITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQT 444
+ Q H++ + P+ P P+A S +P + SP P Q
Sbjct: 507 QRLQL--QQLQHMQHQSQPS-----------PRQHSPVASQITSPIPAIGSPQPASQQHQ 553
Query: 445 PQ 446
Q
Sbjct: 554 SQ 555
Score = 34.3 bits (77), Expect = 0.46
Identities = 45/202 (22%), Positives = 78/202 (38%), Gaps = 24/202 (11%)
Query: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPL 327
PPI PP + P+ +P L P + P Q PPQS P
Sbjct: 62 PPITPPP----ESDPALGMPDVLLPFQALSDPLPSQGSEFTP-------QFPPQSLDLPS 110
Query: 328 VSQAQALPGQ--MLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQM 385
++ ++ L Q +L++ L ++ V Q P + + T A V P Q+
Sbjct: 111 ITISRNLVEQDGVLHSSG-LHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQL 169
Query: 386 IT----EALAQGGMHIRARFPPTTAVS------AIPSSSIPLGRQPMAQVSQSSLPMLSS 435
T + AQ G+++ P T+ S A PS S + + + +++ ++
Sbjct: 170 TTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIGEKRAA 229
Query: 436 PSPGQQVQTPQSMPPPPQPSPQ 457
P G++ +TP+ PQ
Sbjct: 230 PDSGKKPKTPKKKKKKDPNEPQ 251
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 99.4 bits (246), Expect = 1e-20
Identities = 72/155 (46%), Positives = 83/155 (53%), Gaps = 24/155 (15%)
Query: 147 ATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
+ P TQ+ ++Q QQ Q Q QQQQQ QQQQQ QQ QQ Q QQ M QQ
Sbjct: 426 SAPSTQVS---PSVQTQQHQMQLQQQQQ---QQQQQMQQMQQQQLQQHQMHQQI------ 473
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL-QRIAQLQLQQQQQQQQQQQQQQQQALQ 265
QQQ QQQH H QQ +QQQQQ L Q+I Q QLQQQ QQ+ Q QQ Q Q
Sbjct: 474 -----QQQMQQQH---FQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQ 525
Query: 266 AQP-PIQQPPM--QQPQPPPSQALPQQLQQMHHTQ 297
+QP P Q P+ Q P P+ PQ Q H +Q
Sbjct: 526 SQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQ 560
Score = 97.1 bits (240), Expect = 6e-20
Identities = 73/163 (44%), Positives = 81/163 (49%), Gaps = 19/163 (11%)
Query: 135 GMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS 194
G AP + S T Q Q+QLQQ QQQQQ QQ QQQQ Q QQ QQQ Q Q Q
Sbjct: 425 GSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQH 484
Query: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
MQQ Q QQQQ LQQQ NQQQ+QQQ QQ ++ QLQ Q Q Q
Sbjct: 485 HMQQHLQ---QQQQHLQQQ------------INQQQLQQQLQQRLQLQQLQ-HMQHQSQP 528
Query: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQ 297
+Q A Q PI P + PQ P SQ Q+Q TQ
Sbjct: 529 SPRQHSPVASQITSPI--PAIGSPQ-PASQQHQSQIQSQTQTQ 568
Score = 89.4 bits (220), Expect = 1e-17
Identities = 65/160 (40%), Positives = 73/160 (45%), Gaps = 28/160 (17%)
Query: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Q QQ Q Q QQ QQQ QQQQQ+QQ QQQQ ++H Q QQQ+QQQ Q
Sbjct: 437 QTQQHQMQLQQ---QQQ-----QQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ 488
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPP 302
LQ QQQ QQQ QQQ QQ LQ + QLQQ+ H QH P
Sbjct: 489 HLQQQQQHLQQQINQQQLQQQLQQR--------------------LQLQQLQHMQHQSQP 528
Query: 303 PQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Q PVA S +P QP Q Q+ TQ
Sbjct: 529 SPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 568
Score = 63.2 bits (152), Expect = 9e-10
Identities = 55/151 (36%), Positives = 67/151 (44%), Gaps = 16/151 (10%)
Query: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
Q QQ Q QLQ QQQQQQQQQ QQ QQQ LQ QQ Q Q + Q
Sbjct: 437 QTQQHQMQLQ-------QQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH 489
Query: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
LQQ QH Q QQ Q Q Q Q Q + Q+Q P Q P +
Sbjct: 490 LQQQQ--QHLQQQINQQQ---LQQQLQQRLQLQQLQHMQHQSQPSPRQ---HSPVASQIT 541
Query: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVA 380
+P+ P QP QQ Q+ +Q+ Q+++
Sbjct: 542 SPIPAIGSP-QPASQQHQSQIQSQTQTQVLS 571
Score = 43.1 bits (100), Expect = 0.001
Identities = 100/482 (20%), Positives = 161/482 (33%), Gaps = 71/482 (14%)
Query: 6 QETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIH 65
Q D S + LV Q GV HS +SH + +D SL+ R I+H
Sbjct: 109 QSLDLPSITISRNLVEQ-------DGVLHSSGLHMDQSHTQVSQYRQDP--SLIMRSIVH 159
Query: 66 FRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRG---PGQSLGGMGSLGAMGQP 122
D A+ S M Q T + +A +G+ G P S S A P
Sbjct: 160 MTD-------AARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSP 212
Query: 123 MSLSGQ----------------PPPGTSGMAPHSMAVVSTATPQTQLQLQ-------QVA 159
S + P G P PQ + Q A
Sbjct: 213 SSSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAA 272
Query: 160 LQQQQQQQQFQQQQQ--AALQQQQQQQQQQQFQAQQSAMQQQF-QAVVQQQQQLQQQQQQ 216
++ Q F + + A++ ++Q+Q ++ + A ++++ +A+ + L +
Sbjct: 273 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAA 332
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQ---QQQQQQQQQQQQQALQAQPPIQQP 273
+ + QQ + + L Q Q QQ +++ +P +
Sbjct: 333 ESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRL 392
Query: 274 PMQQ-------PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQP 326
PM Q PS + M T P Q P Q Q Q+ Q Q Q
Sbjct: 393 PMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAP-STQVSPSVQTQQHQMQLQQQQQQ 451
Query: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQ--QPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
Q Q + Q L + ++ M Q Q +Q +QQQQ +Q Q + +Q
Sbjct: 452 QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 511
Query: 385 MITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQT 444
+ Q H++ + P+ P P+A S +P + SP P Q
Sbjct: 512 QRLQL--QQLQHMQHQSQPS-----------PRQHSPVASQITSPIPAIGSPQPASQQHQ 558
Query: 445 PQ 446
Q
Sbjct: 559 SQ 560
Score = 34.3 bits (77), Expect = 0.46
Identities = 45/202 (22%), Positives = 78/202 (38%), Gaps = 24/202 (11%)
Query: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPL 327
PPI PP + P+ +P L P + P Q PPQS P
Sbjct: 67 PPITPPP----ESDPALGMPDVLLPFQALSDPLPSQGSEFTP-------QFPPQSLDLPS 115
Query: 328 VSQAQALPGQ--MLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQM 385
++ ++ L Q +L++ L ++ V Q P + + T A V P Q+
Sbjct: 116 ITISRNLVEQDGVLHSSG-LHMDQSHTQVSQYRQDPSLIMRSIVHMTDAARSGVMPPAQL 174
Query: 386 IT----EALAQGGMHIRARFPPTTAVS------AIPSSSIPLGRQPMAQVSQSSLPMLSS 435
T + AQ G+++ P T+ S A PS S + + + +++ ++
Sbjct: 175 TTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIGEKRAA 234
Query: 436 PSPGQQVQTPQSMPPPPQPSPQ 457
P G++ +TP+ PQ
Sbjct: 235 PDSGKKPKTPKKKKKKDPNEPQ 256
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 97.4 bits (241), Expect = 4e-20
Identities = 134/518 (25%), Positives = 184/518 (35%), Gaps = 85/518 (16%)
Query: 71 NKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPP 130
NK+ + V+ AL + G A PPR G L +M +
Sbjct: 2614 NKRLASPVAP--GALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTS 2671
Query: 131 PGTSGMAPHSMAVVSTAT----PQ----TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQ 182
S + ++ V T PQ T +QL + Q QQQQQ QQQQQ
Sbjct: 2672 VTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQ 2731
Query: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
QQQQQQ Q QQ QQ Q Q+Q Q Q + + + + + Q+Q
Sbjct: 2732 QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQ----- 2786
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ-PQ------PPPSQAL--------- 286
+LQ+ Q Q Q Q Q Q QPP QQ PQ P P L
Sbjct: 2787 KLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQ 2846
Query: 287 --------PQQLQQMHHTQHHQPPPQP---QQPPVAQNQPSQL-PPQSQTQPL------- 327
QLQ Q P P +PPV + + P T P+
Sbjct: 2847 VARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISV 2906
Query: 328 -VSQAQALPGQMLYTQP----PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-AP 381
+ Q Q GQ + QP L ++ V QQ +QPQ Q AVQ AQ + P
Sbjct: 2907 AIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTP 2966
Query: 382 GVQMITEALAQ-------------------GGMHIRARFP----PTTAVSAIPSSSIPLG 418
G Q AQ G ++ + P P +SI
Sbjct: 2967 GAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQV 3026
Query: 419 RQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPS 478
Q S ++ + + + GQQVQ M P + Q Q V++ AP +
Sbjct: 3027 ASASQQASPQTVALTQATAAGQQVQ----MIPAVTATAQVVQQKLIQQQVVTTASAPLQT 3082
Query: 479 SFLPSPSPQPSQSPVTARTPQ-NFSVPSPGPLNTPVNP 515
P+P+ P+ S ++ P+ VP+ L TP P
Sbjct: 3083 PGAPNPAQVPASSDSPSQQPKLQMRVPAV-RLKTPTKP 3119
Score = 95.9 bits (237), Expect = 1e-19
Identities = 136/530 (25%), Positives = 182/530 (34%), Gaps = 105/530 (19%)
Query: 85 LQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGM-APHSMAV 143
+ ++ G PAA I P + G + + G + QPPP G A + +
Sbjct: 2599 VNTIAGVPAATFQSINKRLASP-VAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDL 2657
Query: 144 VSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAV 203
VS AT Q + V Q A Q Q ++ FQ +
Sbjct: 2658 VSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLL 2717
Query: 204 VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQA 263
QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q Q+Q Q Q Q Q Q +A
Sbjct: 2718 RQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKA 2771
Query: 264 LQAQPP----------IQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ--PQQPPVA 311
+ P +Q PP QP PP +Q+ P Q Q QPP Q PQ V
Sbjct: 2772 VGKLTPEHLIKMQKQKLQMPP--QPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVT 2829
Query: 312 QNQP----------------------SQLPPQSQTQ--------------PLVS------ 329
+P SQL Q Q Q P+VS
Sbjct: 2830 APRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVV 2889
Query: 330 --------------------QAQALPGQMLYTQP----PLKFVRAPMVVQQPPVQPQVQQ 365
Q Q GQ + QP L ++ V QQ +QPQ Q
Sbjct: 2890 SSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQ 2949
Query: 366 QQTAVQTAQAAQMVA-PGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQ 424
AVQ AQ + PG Q AQ + + P + + + +Q Q
Sbjct: 2950 GPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGA-----QQVQTQ 3004
Query: 425 VSQSSLP-MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 483
+ + LP ++ +P +Q S P ++ V PA + ++ +
Sbjct: 3005 IQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQ 3064
Query: 484 PSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYL 533
Q TA P L TP P+ PA S +Q L
Sbjct: 3065 QKLIQQQVVTTASAP----------LQTPGAPNPAQVPASSDSPSQQPKL 3104
Score = 90.1 bits (222), Expect = 7e-18
Identities = 107/367 (29%), Positives = 148/367 (40%), Gaps = 47/367 (12%)
Query: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQ 255
+Q +++V Q Q Q + + H Q +Q QQQQQQ Q Q Q QQQQQQQQQ
Sbjct: 2685 VQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQ---QQQQQQQQQQQQQ 2741
Query: 256 QQQQQQQALQAQPPIQQPPMQQPQPPPSQAL----PQQLQQMHHTQHHQPPPQPQQPPVA 311
QQQQQQ +Q + Q Q P +A+ P+ L +M Q Q PPQP PP A
Sbjct: 2742 QQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKM-QKQKLQMPPQP-PPPQA 2799
Query: 312 QNQPSQ----------LPPQSQTQPLVSQAQALPGQML--YTQPPLKFVRAPMVVQQPPV 359
Q+ P Q PPQ Q+ L + PG +L T L+ R V +
Sbjct: 2800 QSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTR-VPTSQL 2858
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGR 419
Q Q Q Q A Q AQ A P V + ++ G+ TT + S+ +G
Sbjct: 2859 QAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGV--------TTLPMNVAGISVAIG- 2909
Query: 420 QPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSS 479
QP Q+ +++ P QQ+ + Q + QP + GPA
Sbjct: 2910 QPQKAAGQT---VVAQPVHMQQLLKLKQQAVQQQKAIQP---------QAAQGPAAVQQK 2957
Query: 480 FLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQL 539
P A Q L TP+ S AG+ Q + Q + KL Q+
Sbjct: 2958 ITAQQITTPGAQQKVAYAAQ--PALKTQFLTTPI--SQAQKLAGAQQVQTQIQVAKLPQV 3013
Query: 540 SKYIEPL 546
+ P+
Sbjct: 3014 VQQQTPV 3020
Score = 80.9 bits (198), Expect = 4e-15
Identities = 117/492 (23%), Positives = 194/492 (39%), Gaps = 82/492 (16%)
Query: 86 QSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVS 145
Q L G P G R PG L G G GA G M+ PPP TS P AV
Sbjct: 281 QVLQGPPLPRPLGF---ERTPGVLLPGAG--GAAGFGMT---SPPPPTS---PSRTAVPP 329
Query: 146 TATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQ 205
+ + +++ ++ + + Q ++Q +Q Q A+++ F+ +
Sbjct: 330 GLSSLPLTSVGNTGMKKVPKKLEEIPPASPEMAQMRKQCLDYHYQEMQ-ALKEVFKEYLI 388
Query: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQ---- 261
+ LQ Q + ++ +Q +Q L ++++++++++++++ +
Sbjct: 389 ELFFLQHFQGNMMDFLAFKKKHYAPLQAYLRQ----NDLDIEEEEEEEEEEEEKSEVIND 444
Query: 262 -QALQ------AQPPIQQPPMQQPQPPPSQALPQQ-----LQQMHHTQHHQPPPQPQQPP 309
QAL A ++ ++ Q PS + +Q L+ H Q P P
Sbjct: 445 EQALAGSLVAGAGSTVETDLFKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVP 504
Query: 310 VAQNQPSQ---LPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRA------PMVVQQPPVQ 360
+ Q P+ +PP Q L Q Q+ T PP++ + + + PP
Sbjct: 505 LQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAG 564
Query: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQ 420
+A+Q AQ Q+V Q+ Q P + A PSS +P+
Sbjct: 565 VPTAALSSALQFAQQPQVVEAQTQLQIPVKTQ---------QPNVPIPAPPSSQLPI--- 612
Query: 421 PMAQVSQSSLPMLSSPSPGQ-QVQTPQ----------------SMPPPPQPSPQPGQPSS 463
P +Q +Q +L + P+PG+ QVQ Q PP P+P P S
Sbjct: 613 PPSQPAQLALHV---PTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSL 669
Query: 464 QPNSNVSSGPAPSPSSFL--PSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSP 521
P S GP+P+ SS + PS + + SPVT+RTP + + P P S
Sbjct: 670 APVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVVA-------SAPTKPQSPAQN 722
Query: 522 AGSSQAEEQQYL 533
A SSQ Q L
Sbjct: 723 ATSSQDSSQDTL 734
Score = 67.8 bits (164), Expect = 4e-11
Identities = 83/372 (22%), Positives = 147/372 (39%), Gaps = 53/372 (14%)
Query: 240 RIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH 299
++A L+ ++ ++++ QQ+ QP + QPP QPQPPP PQ
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQ---QPAVAQPPPPQPQPPPP---PQ----------- 2518
Query: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV 359
QPPP QP A +QP PP Q QP Q Q P QP V+AP
Sbjct: 2519 QPPPPLPQPQAAGSQPPAGPPAVQPQP-QPQPQTQP------QP----VQAP-----AKA 2562
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSI-PLG 418
QP + +A A + G M T A++ + ++ +P+++ +
Sbjct: 2563 QPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVI--------VNTIAGVPAATFQSIN 2614
Query: 419 RQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPS 478
++ + V+ +L +P Q V T PPP+ P + S ++ + +
Sbjct: 2615 KRLASPVAPGALTTPGGSAPAQVVHT----QPPPRAVGSPATATPDLVSMATTQGVRAVT 2670
Query: 479 SFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQ 538
S S + +PV +TP VP P ++PA +QQ + +Q
Sbjct: 2671 SVTASAVVTTNLTPV--QTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQ 2728
Query: 539 LSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKC--EIALEKLK 596
+ + ++ + + + ++ + P++ +K + K E ++ K
Sbjct: 2729 QQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQ---IKAVGKLTPEHLIKMQK 2785
Query: 597 NDMAVPTPPPPP 608
+ +P PPPP
Sbjct: 2786 QKLQMPPQPPPP 2797
Score = 57.4 bits (137), Expect = 5e-08
Identities = 83/282 (29%), Positives = 105/282 (37%), Gaps = 68/282 (24%)
Query: 86 QSLTGGPAAGAAGIGMPP---------RGPGQSLGGMGSLG---AMGQPMSLSGQPPPGT 133
Q T P + PP PG + M G A+GQP +GQ
Sbjct: 2863 QMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQT---- 2918
Query: 134 SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ-------Q 186
V Q L+L+Q A+QQQ+ Q Q AA+QQ+ QQ Q
Sbjct: 2919 --------VVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQ 2970
Query: 187 QQFQAQQSAMQQQFQAV-VQQQQQLQ--QQQQQQQHLIKLHHQNQQQ-----IQQ----- 233
+ A Q A++ QF + Q Q+L QQ Q Q + KL QQQ IQQ
Sbjct: 2971 KVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASAS 3030
Query: 234 QQQQLQRIAQLQLQQQQQQQQ-------------QQQQQQQQALQAQPPIQQPPMQQP-Q 279
QQ Q +A Q QQ Q Q+ QQQ A P+Q P P Q
Sbjct: 3031 QQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQ 3090
Query: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321
P S P Q QP Q + P V P++ P Q
Sbjct: 3091 VPASSDSPSQ----------QPKLQMRVPAVRLKTPTKPPCQ 3122
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 390 LAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP 449
LA+ G++ PP V+++ + I ++ +A ++ P ++ P P Q PQ P
Sbjct: 2461 LAESGINYDKPLPPIQ-VASLRAERIAKEKKALADQQKAQQPAVAQPPPPQ----PQPPP 2515
Query: 450 PPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTP 498
PP QP P QP + S P P + P P PQP P + P
Sbjct: 2516 PPQQPPPPLPQPQA-----AGSQPPAGPPAVQPQPQPQPQTQPQPVQAP 2559
Score = 50.1 bits (118), Expect = 8e-06
Identities = 77/294 (26%), Positives = 106/294 (36%), Gaps = 35/294 (11%)
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPI---QQPPMQQPQPPPSQALP--QQLQQMHHTQHH 299
Q+QQ + Q LQ+ P+ Q P P PS P Q Q +H
Sbjct: 57 QIQQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHG 116
Query: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQAL---------PGQMLYTQPPLK-FVR 349
P P++Q Q+ QS TQP QAL PG L + P FV
Sbjct: 117 SPSYIQVTSPLSQ----QVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVD 172
Query: 350 APMVVQQPPVQPQ------VQQQQTAVQTAQAAQMVA--PGVQMITEALAQGGMHIRARF 401
A ++V+Q + P Q Q AQ AQ+ PG + H ++
Sbjct: 173 ASVLVRQISLSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGG 232
Query: 402 PPTTAVSAIPSSSIPLGRQPMAQVSQSSL----PMLSSPSPGQQVQTPQSMPPPPQPSPQ 457
P+++ G QP+A S + P +SS GQ VQ Q + PP P P
Sbjct: 233 TIHHLGPQSPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPL 292
Query: 458 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNT 511
+ V A + F + P P+ TA P S+P NT
Sbjct: 293 ----GFERTPGVLLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNT 342
Score = 45.8 bits (107), Expect = 2e-04
Identities = 105/457 (22%), Positives = 154/457 (33%), Gaps = 62/457 (13%)
Query: 222 KLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPP 281
K+ + ++I R A +L+ + Q Q Q+ + P PP + P
Sbjct: 1397 KIPRKLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPSTHPP-RTAAPT 1455
Query: 282 PSQALPQ---QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQM 338
+ A PQ + + T P + P +Q S P+ Q S A A P
Sbjct: 1456 TASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTA-ASPAH- 1513
Query: 339 LYTQPPLKFVRAPMVVQ-----QPPVQPQVQQQQTAVQTAQAAQMVAPG----------V 383
P K +RA Q QPP QPQ A Q+A ++V P V
Sbjct: 1514 -----PAK-LRAQTTAQASTPGQPPPQPQAPSH-AAGQSALPQRLVLPSQAQARLPSGEV 1566
Query: 384 QMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443
I + + G R P T S L + Q++ P+ S Q V
Sbjct: 1567 VKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQ-PLQLQGSVLQIVS 1625
Query: 444 TPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQN-FS 502
P P P P Q SQ + V P + PSP+P Q V R N +
Sbjct: 1626 AP-GQPYLRAPGPVVMQTVSQAGA-VHGALGSKPPAGGPSPAPLTPQVGVPGRVAVNALA 1683
Query: 503 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNED---- 558
V PG + P SP G EE+ L K + Y+ RR D
Sbjct: 1684 VGEPGTASKPA------SPIGGPTQEEKTRLLKERLDQIYLVNERRCSQAPVYGRDLLRI 1737
Query: 559 ------------------RKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA 600
R K+ S PS+ + TL +C +L+ + + +A
Sbjct: 1738 CALPSHGRVQWRGSLDGRRGKEAGPAHSYTSSSESPSEL--MLTLCRCGESLQDVIDRVA 1795
Query: 601 VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHS 637
PP PP+ + PL + +R + H+
Sbjct: 1796 FVIPPVVAAPPSLRVPRPPPLYSHRMRILRQGLREHA 1832
Score = 41.2 bits (95), Expect = 0.004
Identities = 86/384 (22%), Positives = 122/384 (31%), Gaps = 93/384 (24%)
Query: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQ----QQQALQAQPPIQQPPMQQPQPPPS-QALP 287
QQ+ Q +AQ Q Q QQ Q QA +QPP PP QPQP P Q P
Sbjct: 2495 QQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAG-PPAVQPQPQPQPQTQP 2553
Query: 288 QQLQQMHHTQ---------------------HHQPPPQPQQPPVAQNQPSQLPP---QSQ 323
Q +Q Q P V N + +P QS
Sbjct: 2554 QPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSI 2613
Query: 324 TQPLVSQAQ---------ALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374
+ L S + P Q+++TQPP + V +P V Q AV +
Sbjct: 2614 NKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVT 2673
Query: 375 AAQMV--------------------APGVQMITEALAQGGMHI----------------- 397
A+ +V A GVQ+ + + +
Sbjct: 2674 ASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQ 2733
Query: 398 --------RARFPPTTAVSAIPSSSIPLGRQPMAQVSQ--SSLPMLSSPSPGQQVQTPQS 447
+ + TT S + I Q AQ+ P Q++Q P
Sbjct: 2734 QQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMP-P 2792
Query: 448 MPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPG 507
PPPPQ P QP++Q S P +P+P + +T T N V
Sbjct: 2793 QPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPG-ALLTGTTVANLQVARLT 2851
Query: 508 PLNTPVNPSSVMSPAGSSQAEEQQ 531
+ P+S + G Q + Q
Sbjct: 2852 RV-----PTSQLQAQGQMQTQAPQ 2870
Score = 36.2 bits (82), Expect = 0.12
Identities = 106/483 (21%), Positives = 165/483 (34%), Gaps = 96/483 (19%)
Query: 70 HNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQP 129
H S V+ P++ Q T P P GPGQ+L + + GA G + L
Sbjct: 115 HGSPSYIQVTSPLSQ-QVQTQSPT-------QPSPGPGQALQNVRA-GAPGPGLGLCSSS 165
Query: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189
P G G S+ V +Q++L F Q + L Q Q Q Q
Sbjct: 166 PTG--GFVDASVLV------------RQISLSPSSGGH-FVFQDGSGLTQIAQGAQVQ-- 208
Query: 190 QAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQ------------------- 230
+Q + ++++ Q Q I HH Q
Sbjct: 209 ------LQHPGTPITVRERRPSQPHTQSGGTI--HHLGPQSPAAAGGAGLQPLASPSHIT 260
Query: 231 IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPP--------MQQPQPPP 282
Q+ I Q QL QQQQ Q + + P + P M P PP
Sbjct: 261 TANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVLLPGAGGAAGFGMTSPPPPT 320
Query: 283 SQ---ALPQQLQQMH-----HTQHHQPPPQ-----PQQPPVAQNQPSQLPPQSQTQPLVS 329
S A+P L + +T + P + P P +AQ + L Q +
Sbjct: 321 SPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPASPEMAQMRKQCLDYHYQEMQALK 380
Query: 330 QA-----------QALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378
+ Q G M+ K AP+ +++++ + +
Sbjct: 381 EVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEEEEEKSE 440
Query: 379 VAPGVQMITEALAQG-GMHIRARFPPTTAVSAIPSSSIP-LGRQPMAQVSQSSL----PM 432
V Q + +L G G + A+PS+ + ++P +V + P
Sbjct: 441 VINDEQALAGSLVAGAGSTVETDL--FKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPG 498
Query: 433 LSSPSPGQQVQ-TPQS-MPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ-PS 489
+ P QQ+ T Q MPP PQ + GQ SQ + S+GP ++ L +P PQ P
Sbjct: 499 ADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPG 558
Query: 490 QSP 492
+ P
Sbjct: 559 RLP 561
Score = 30.8 bits (68), Expect = 5.1
Identities = 43/167 (25%), Positives = 58/167 (34%), Gaps = 23/167 (13%)
Query: 298 HHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQP 357
HH PQ Q Q Q S+ P S+ + + P P F AP
Sbjct: 2 HHGTGPQNVQH---QLQRSRACPGSEGEEQPAHPNPPPS------PAAPF--APSASPSA 50
Query: 358 PVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFP------PTTAVSAIP 411
P P Q QQ ++ Q V +Q + + A P P SA P
Sbjct: 51 PQSPSYQIQQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQP 110
Query: 412 ------SSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 452
S S P++Q Q+ P SP PGQ +Q ++ P P
Sbjct: 111 RRFEHGSPSYIQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGP 157
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 96.7 bits (239), Expect = 8e-20
Identities = 107/346 (30%), Positives = 136/346 (39%), Gaps = 45/346 (13%)
Query: 210 LQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP 269
+QQQ L HH Q +Q QLQ QQQQQQQQQQQQQQQQ Q Q
Sbjct: 226 IQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ 285
Query: 270 IQ-QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA-QNQPSQLPPQSQTQPL 327
+Q +PP Q Q P PQ TQ PP Q P A Q P+Q + T
Sbjct: 286 LQARPPQQHQQQQPQGIRPQFTAP---TQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342
Query: 328 VSQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT-----AQAAQMV 379
+ LPG Q L +P L V+ P PP P QQ + T + Q
Sbjct: 343 GWKKAPLPGPMQQQLQARPSLATVQTPS--HPPPPYPFGSQQASQAHTNFPQMSNPGQFT 400
Query: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
AP ++ + QGG +R P + + S Q S +S P ++
Sbjct: 401 APQMKSL-----QGG---PSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVN----- 447
Query: 440 QQVQTPQSM-PPPPQPSPQP---GQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP--- 492
QT Q M P PPQ +P P QP S P N P +F+ P+Q P
Sbjct: 448 ---QTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSL 504
Query: 493 ------VTARTPQNFSVPSPGP-LNTPVNPSSVMSPAGSSQAEEQQ 531
+ R P FS P PS+ + G+S A + Q
Sbjct: 505 HPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQ 550
Score = 90.1 bits (222), Expect = 7e-18
Identities = 135/478 (28%), Positives = 172/478 (35%), Gaps = 79/478 (16%)
Query: 71 NKKSQASVSDPMNALQSL---TGGPAAGAAGI---------GMPPRGPGQSLGGMGSLGA 118
N+ ++ PM A S+ G P A GI +PP G S S+ A
Sbjct: 142 NRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSS-----SMMA 196
Query: 119 MG----------QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQ 168
G +P S S P SG+ + S + +Q V++ +Q
Sbjct: 197 PGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPAN 256
Query: 169 FQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQ 228
F Q QQ QQQQQQQQQQQ Q QQ QQQ QA QQ QQQQ Q + Q
Sbjct: 257 FPQLQQQQQQQQQQQQQQQQQQQQQ--QQQQLQARPPQQ---HQQQQPQGIRPQFTAPTQ 311
Query: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288
+ QL A LQ Q Q + + P+ P QQ Q PS A Q
Sbjct: 312 VPVPPGWNQLPSGA---LQPPPAQGSLGTMTANQGWK-KAPLPGPMQQQLQARPSLATVQ 367
Query: 289 QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFV 348
T H PPP P A + P S PGQ +T P +K +
Sbjct: 368 -------TPSHPPPPYPFGSQQASQAHTNFPQMSN-----------PGQ--FTAPQMKSL 407
Query: 349 R-APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAV 407
+ P V P QP + + A + Q + + Q G P
Sbjct: 408 QGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGF 467
Query: 408 SAIPSSSIPLGRQPMAQVSQSSLP---MLSSPSPGQQVQTPQSMPPPPQPSPQ---PGQP 461
SS GR PM Q Q ++P M+ P Q PQS+ P P+ PG
Sbjct: 468 QQPVSSP---GRNPMVQ--QGNVPPNFMVMQQQPPN--QGPQSLHPGLGGMPKRLPPGFS 520
Query: 462 SSQPNSNVSSGPAPSPSSFLPSPSPQPS---------QSPVTARTPQNFSVPSPGPLN 510
+ Q N N G PS ++ P S P A PQN S GP N
Sbjct: 521 AGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPN 578
Score = 65.1 bits (157), Expect = 2e-10
Identities = 89/361 (24%), Positives = 123/361 (34%), Gaps = 45/361 (12%)
Query: 170 QQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQ 229
Q +Q LQQ Q Q Q QQ + QQQQ Q Q Q
Sbjct: 976 QPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQ----------- 1024
Query: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
Q QQQQQQ+ + +Q + + Q P Q+ PMQQ P Q
Sbjct: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG 1084
Query: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
+ + Q P P P+ N + +S P S P + + P
Sbjct: 1085 PASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSS-----PLAEMASLPEASGSE 1139
Query: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRA---RFPPTTA 406
AP V P P + +V P Q++ G + A P
Sbjct: 1140 APSVPGGPNNMP--------------SHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPP 1185
Query: 407 VSAIPSS---SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS 463
V+++PSS P P Q S+ P +SP P QTP + PP +PS P
Sbjct: 1186 VNSLPSSHGHHFPNVAAP-TQTSRPKTPNRASPRP-YYPQTPNNRPPSTEPSEISLSPE- 1242
Query: 464 QPNSNVSSGPAPSPSSFLPSPSPQPSQS---PVTARTPQNFSVPSPGPLNTPVNPSSVMS 520
N S P +P P P+P+ + P P N +NPS+ +
Sbjct: 1243 --RLNASIAGLFPPQINIPLP-PRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFAT 1299
Query: 521 P 521
P
Sbjct: 1300 P 1300
Score = 60.1 bits (144), Expect = 8e-09
Identities = 153/703 (21%), Positives = 240/703 (34%), Gaps = 101/703 (14%)
Query: 72 KKSQASVSDPMN---ALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMS---L 125
K SQ ++ P L+ P G GI + GP G QP+ L
Sbjct: 924 KNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPL 983
Query: 126 SGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAA--LQQQQQQ 183
PP +AP PQ QQQ Q Q QQQQ Q Q QQ
Sbjct: 984 QQMPPQLMQHVAP---------PPQPP---------QQQPQPQLPQQQQPPPPSQPQSQQ 1025
Query: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
QQQQQ Q M QQ V +L Q L+ +Q+ QQ + +
Sbjct: 1026 QQQQQQQMMMMLMMQQDPKSV----RLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVS 1081
Query: 244 LQLQQQQQQQQQQQQQQQQALQAQPPI-----QQPPMQQPQPPPSQALPQ--QLQQMHHT 296
L Q +Q+ + P+ + + PQ P S L + L + +
Sbjct: 1082 L---QGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS 1138
Query: 297 QHHQPPPQPQQPP----VAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKF----- 347
+ P P P + QNQ P+ PL + A P Q P
Sbjct: 1139 EAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198
Query: 348 -VRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMH--IRARFPPT 404
V AP +P + + QT P + +L+ ++ I FPP
Sbjct: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNR---PPSTEPSEISLSPERLNASIAGLFPPQ 1255
Query: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 464
+ P ++ G ++ ++L + +P P + P +S
Sbjct: 1256 INIPLPPRPNLNRGFDQQG-LNPTTLKAIGQ-APSNLTMNPSNFATPQTHKLDSVVVNSG 1313
Query: 465 PNSNVSSGPAPSPSS-----------FLPSPSPQPSQSP-------VTARTPQNFSVP-- 504
SN + SPS+ PSP Q S++P A QN +P
Sbjct: 1314 KQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRN 1373
Query: 505 ---SPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKK 561
SP PL P P S + +G Q + + +E NK N +
Sbjct: 1374 VLVSPTPLANPPVPGSFPNNSG---LNPQNSTVSVAAVGGVVED-----NKESLNVPQDS 1425
Query: 562 DLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPL 621
D +S + + K P + + K + ++ K D P+ P + + L P
Sbjct: 1426 DCQNSQSRKEQVNIELKAVPAQEV-KMVVPEDQSKKD-GQPSDPNKLPSVEENKNLVSPA 1483
Query: 622 LDAVLANIRSPVFNHSLYRTFV--PAMTAIHGPPITAPVVCTRKRRLEDDERQSIPSVLQ 679
+ ++ + N + P +T + +T PVV ED ++ S+ LQ
Sbjct: 1484 MREAPTSLSQLLDNSGAPNVTIKPPGLTDLE---VTPPVVSG-----EDLKKASVIPTLQ 1535
Query: 680 GEVARLDPKFLVNLDPSHCSNNGTVH-LICKLDDKDLPSVPPL 721
+ +P +NL S+ + VH + ++ PS+PP+
Sbjct: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPV 1578
Score = 53.5 bits (127), Expect = 7e-07
Identities = 95/419 (22%), Positives = 134/419 (31%), Gaps = 52/419 (12%)
Query: 74 SQASVSDPMNALQ-SLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG 132
+++ S P + Q S P M PR P + G QP+S G+ P
Sbjct: 425 NKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQG----FQQPVSSPGRNPMV 480
Query: 133 TSGMAPHSMAVVSTATPQTQLQLQQVAL------------QQQQQQQQFQQQQQAALQQQ 180
G P + V+ P Q L Q Q Q +
Sbjct: 481 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT 540
Query: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQ----QQQQHLIKLHHQNQQQIQQQQQ 236
Q QA Q+ Q Q Q+Q Q L+ +H + QQ
Sbjct: 541 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN----MNNQQA 596
Query: 237 QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ---PPPSQALPQQLQQM 293
+ Q+ L Q Q QQ Q + Q Q M Q Q P + + + Q M
Sbjct: 597 GTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLM 656
Query: 294 HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV 353
Q PP P Q PP+ Q A QM+ Q + + PM+
Sbjct: 657 PQGQMMVNPPSQNLGPSPQR---MTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMI 713
Query: 354 VQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSS 413
Q Q Q +QQ Q V PG I PT + +
Sbjct: 714 EQIMTNQMQGNKQQF---NTQNQSNVMPGPAQIMRG-------------PTPNMQ---GN 754
Query: 414 SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP--SPQPGQPSSQPNSNVS 470
+ Q Q+ P+ +SPS +Q PP P P + Q G P++ N++VS
Sbjct: 755 MVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVS 813
Score = 52.8 bits (125), Expect = 1e-06
Identities = 116/502 (23%), Positives = 161/502 (32%), Gaps = 94/502 (18%)
Query: 108 QSLGGMGSLGAMGQPMSLSGQPP----PGTSGMAPH--SMAVVSTATPQTQLQLQQVALQ 161
Q GG G+ G M +S PP P G+ + + ++ PQ L Q Q
Sbjct: 556 QHAGGQGA-GPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQ 614
Query: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQ---------- 211
Q Q QQ Q Q QQQ Q + + Q + Q Q +
Sbjct: 615 QGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSP 674
Query: 212 ------QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQ 265
+Q QQ + NQ Q Q LQ+ ++ Q Q +QQ Q
Sbjct: 675 QRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQS 734
Query: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
P M+ P P + Q QM PQQ PV N PSQ+
Sbjct: 735 NVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM------LPQQGPV-NNSPSQV------- 780
Query: 326 PLVSQAQAL----PGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAP 381
+ Q Q L P + Q A V + P V QQT MV P
Sbjct: 781 -MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQT--------NMVPP 831
Query: 382 GVQMITEALAQG------GMHIRARF---PPTTAVSAIPSSSIPLGRQP------MAQVS 426
VQ + A G GM A F P +S + P+ + + +
Sbjct: 832 HVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLL 891
Query: 427 QSSL-----------------------PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS 463
QS + P + Q + TP + P + + QP P
Sbjct: 892 QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGE 951
Query: 464 QPNSNVSSGPAPSPSSFLPS--PSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVM-- 519
Q + +SGP S P PS Q P+ PQ +P P P +
Sbjct: 952 QGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQ 1011
Query: 520 --SPAGSSQAEEQQYLDKLKQL 539
P SQ + QQ + +Q+
Sbjct: 1012 QQQPPPPSQPQSQQQQQQQQQM 1033
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/486 (19%), Positives = 169/486 (34%), Gaps = 66/486 (13%)
Query: 122 PMSLSGQPPPGT----SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL 177
P L+ P PG+ SG+ P + V A V + ++ Q +
Sbjct: 1378 PTPLANPPVPGSFPNNSGLNPQNSTVSVAA----------VGGVVEDNKESLNVPQDSDC 1427
Query: 178 QQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQ 237
Q Q +++Q + + + Q+ + VV + Q + Q + + +N+ + ++
Sbjct: 1428 QNSQSRKEQVNIELK-AVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMRE 1486
Query: 238 LQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ----------PPMQQ----PQPPPS 283
L + L+ PP+ P +Q +P S
Sbjct: 1487 APTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNS 1546
Query: 284 QALPQ-----------QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT-----QPL 327
LP +L ++ PP +P + + + LPP T P+
Sbjct: 1547 LNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPI 1606
Query: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV--QPQVQQQQTAVQTAQAAQMVAP---G 382
+ A + Q L VV P + V + Q+A Q+ Q + P
Sbjct: 1607 TTSANTSAALPTHLQSALMST----VVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFIN 1662
Query: 383 VQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQ-VSQSSLP-----MLSSP 436
I + + P TT +P S +G + Q + SS P + SSP
Sbjct: 1663 SSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSP 1722
Query: 437 SPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLP---SPSPQPSQSPV 493
+P Q P + P P P + S P P SP S
Sbjct: 1723 APNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQN 1782
Query: 494 TARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKI 553
T + Q+ ++ SP N+P + + SP SS+ + + +DK+ Q+ + +++ +
Sbjct: 1783 TLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGK--VDKIGQI-LLTKACKKVTGSL 1839
Query: 554 DKNEDR 559
+K E++
Sbjct: 1840 EKGEEQ 1845
Score = 34.3 bits (77), Expect = 0.46
Identities = 61/300 (20%), Positives = 100/300 (33%), Gaps = 57/300 (19%)
Query: 431 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGP-APSPSSFLPSPSPQPS 489
PM + S + P + P P P NVSS AP P+ L +P+P+
Sbjct: 152 PMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPA 211
Query: 490 QSPVTARTP---------QNFSVPSPGPLNTPVNPSSV---MSPAGSSQAEEQQYLDKLK 537
S A P Q+ S P + P+ P SV M+PA Q ++QQ + +
Sbjct: 212 -SQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQ 270
Query: 538 QLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPS-------------------- 577
Q + + ++ ++ ++ + + + T P+
Sbjct: 271 QQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPP 330
Query: 578 --------------KRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLD 623
K+ PL + ++ + P+ PPPP P QQ
Sbjct: 331 AQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQ-------- 382
Query: 624 AVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVCTRKRRLEDDERQSIPSVLQGEVA 683
A A+ P ++ T P M ++ G P P + S S QG A
Sbjct: 383 ASQAHTNFPQMSNPGQFT-APQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPA 441
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 95.9 bits (237), Expect = 1e-19
Identities = 110/494 (22%), Positives = 195/494 (39%), Gaps = 52/494 (10%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 S--QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM-------- 378
+ Q P + L QP P P P TA +A+ A +
Sbjct: 570 RPVEPQEGPHKSLQDQPTRNLAAFPASHDPDPAIP----APTATPSARGAVIRQNSDPTS 625
Query: 379 VAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSP 438
PG A + + P T+ A ++ G AQ ++ S+
Sbjct: 626 EGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQI 685
Query: 439 GQQVQTPQSMPPPPQPSPQ-PGQPSSQPNSNV---------SSGPAPSPSSFLPSPSPQP 488
Q + + P PP P Q PG P++ N ++ S P+ LP
Sbjct: 686 YLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLE 745
Query: 489 SQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRR 548
+ P + V SPG P + S +++ LD+ + K
Sbjct: 746 RNRVGVSSKPDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSS 805
Query: 549 MINKIDKNEDRKKD 562
+++ +ED +++
Sbjct: 806 SSEEVESSEDDEEE 819
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 93.2 bits (230), Expect = 8e-19
Identities = 114/516 (22%), Positives = 204/516 (39%), Gaps = 76/516 (14%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 SQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA-QAAQMVAPGVQ 384
+ G ++ + PLK AP+ P +Q Q T A A+ P +
Sbjct: 570 RPVEPQEGPHKSLVAHRVPLKPYAAPV-----PRSQSLQDQPTRNLAAFPASHDPDPAIP 624
Query: 385 MITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQP-------MAQVSQSSLPMLSSPS 437
T + G IR PT+ PS + P +P + Q + S L++
Sbjct: 625 APTATPSARGAVIRQNSDPTSEGPG-PSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSG 683
Query: 438 PG--QQVQTPQSMP--------------------PPPQPSPQPGQPSSQPNSNV------ 469
G + Q ++ P PP P+ PG P++ N ++
Sbjct: 684 AGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPG 743
Query: 470 ---SSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQ 526
S P+ LP + P + V SPG P + S
Sbjct: 744 WERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPVLSPGNKAKPDDHRSRPGRPADFV 803
Query: 527 AEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKD 562
+++ LD+ + K +++ +ED +++
Sbjct: 804 LLKERTLDEAPRPPKKAMDYSSSSEEVESSEDDEEE 839
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 92.8 bits (229), Expect = 1e-18
Identities = 110/485 (22%), Positives = 193/485 (39%), Gaps = 51/485 (10%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 SQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA-QAAQMVAPGVQ 384
+ G ++ + PLK AP+ P +Q Q T A A+ P +
Sbjct: 570 RPVEPQEGPHKSLVAHRVPLKPYAAPV-----PRSQSLQDQPTRNLAAFPASHDPDPAIP 624
Query: 385 MITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQP-------MAQVSQSSLPMLSSPS 437
T + G IR PT+ PS + P +P + Q + S L++
Sbjct: 625 APTATPSARGAVIRQNSDPTSEGPG-PSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSG 683
Query: 438 PGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 497
G S P + P S P S P+ LP +
Sbjct: 684 AG------GSRPAQAVRASNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGVSSK 737
Query: 498 PQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNE 557
P + V SPG P + S +++ LD+ + K +++ +E
Sbjct: 738 PDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEEVESSE 797
Query: 558 DRKKD 562
D +++
Sbjct: 798 DDEEE 802
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 91.3 bits (225), Expect = 3e-18
Identities = 103/430 (23%), Positives = 173/430 (40%), Gaps = 51/430 (11%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 SQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA-QAAQMVAPGVQ 384
+ G ++ + PLK AP+ P +Q Q T A A+ P +
Sbjct: 570 RPVEPQEGPHKSLVAHRVPLKPYAAPV-----PRSQSLQDQPTRNLAAFPASHDPDPAIP 624
Query: 385 MITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQP-------MAQVSQSSLPMLSSPS 437
T + G IR PT+ PS + P +P + Q + S L++
Sbjct: 625 APTATPSARGAVIRQNSDPTSEGPG-PSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSG 683
Query: 438 PGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 497
G S P + P S P S P+ LP +
Sbjct: 684 AG------GSRPAQAVRASNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGVSSK 737
Query: 498 PQNFSVPSPG 507
P + V SPG
Sbjct: 738 PDSSPVLSPG 747
Score = 54.7 bits (130), Expect = 3e-07
Identities = 76/351 (21%), Positives = 140/351 (39%), Gaps = 60/351 (17%)
Query: 193 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ------------------- 233
+S ++++F + Q+ + + +QQQ L QQ QQ
Sbjct: 348 ESTLRREFLRLQQENKSNSEALKQQQQL--------QQQQQRDPEAHIKHLLHQRQRRIE 399
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQM 293
+Q++ +R + Q +++++Q++ Q+++QQ+ L+ +++ ++ + +QL++
Sbjct: 400 EQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQ 459
Query: 294 HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV 353
++ Q Q + + Q Q Q Q Q Q Q LPG + PL M
Sbjct: 460 RQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQ---QQQQLLPGD----RKPLYHYGRGMN 512
Query: 354 VQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSS 413
P + +++T + Q LA+ PP IP +
Sbjct: 513 PADKPAWAREVEERTRMNKQQ------------NSPLAKSKPGSTGPEPP------IPQA 554
Query: 414 SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS--SQPNSNVSS 471
S P P++Q P+ P + + +P P +P P S QP N+++
Sbjct: 555 S-PGPPGPLSQTPPMQRPVEPQEGPHKSL-VAHRVPLKPYAAPVPRSQSLQDQPTRNLAA 612
Query: 472 GPAP-SPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSP 521
PA P +P+P+ PS R QN S GP +P NP + + P
Sbjct: 613 FPASHDPDPAIPAPTATPSARGAVIR--QNSDPTSEGPGPSP-NPPAWVRP 660
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 89.7 bits (221), Expect = 9e-18
Identities = 110/360 (30%), Positives = 148/360 (41%), Gaps = 54/360 (15%)
Query: 220 LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ----------------QQQQQQA 263
++ L QN Q QLQ++ QLQLQQQQQQQQQQ Q QQQ
Sbjct: 161 IMTLPLQNLQATSSLNSQLQQL-QLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQP 219
Query: 264 LQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ 323
LQ PP Q PP Q P P+ L Q Q H H Q Q P Q S PPQ
Sbjct: 220 LQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSP---TQQSSSPPQKP 276
Query: 324 TQPLVSQAQALPGQMLYTQP-PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPG 382
+Q S LP + T P PL+ V P+ Q + +++ ++QA
Sbjct: 277 SQ---SPGHGLPSPL--TPPNPLQLVNNPLASQAAAAAAAM----SSIASSQAFGNALSS 327
Query: 383 VQMITEAL---AQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
+Q +T L AQG + P PSS G Q + QV Q P L + + G
Sbjct: 328 LQGVTGQLVTNAQGQIIGTIPLMPNPG----PSSQAASGTQGL-QV-QPITPQLLTNAQG 381
Query: 440 QQVQTPQSMPPPPQPSPQ--------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQP--S 489
Q + T P + Q PGQ QP S S G A S + L Q S
Sbjct: 382 QIIATVIGNQILPVINTQGITLSPIKPGQQLHQP-SQTSVGQAASQGNLLHLAHSQASMS 440
Query: 490 QSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRM 549
QSPV + + S S L+ S+ + AG L+++++ +K + +RR+
Sbjct: 441 QSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN---LEEIREFAKAFK-IRRL 496
Score = 68.2 bits (165), Expect = 3e-11
Identities = 93/347 (26%), Positives = 122/347 (35%), Gaps = 57/347 (16%)
Query: 147 ATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ----QQFQA 202
AT QLQQ+ LQ QQQQQQ QQQ + Q Q Q Q+QQ +Q QQ
Sbjct: 171 ATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPP 230
Query: 203 VVQQ----QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
QQ QLQQ Q QQH H QNQ Q QQ
Sbjct: 231 ASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQ---------------------- 268
Query: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318
P Q+P P LP L + Q P Q A S
Sbjct: 269 ------------SSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIA 316
Query: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378
Q+ L S Q + GQ++ ++ P+ P A Q Q+
Sbjct: 317 SSQAFGNAL-SSLQGVTGQLVTN-------AQGQIIGTIPLMPNPGPSSQAASGTQGLQV 368
Query: 379 VAPGVQMITEALAQ-GGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPS 437
Q++T A Q I + P I S I G+Q + Q SQ+S+ + S
Sbjct: 369 QPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQ-LHQPSQTSVG--QAAS 425
Query: 438 PGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSP 484
G + S S P + +S +S+ SS A S + +P
Sbjct: 426 QGNLLHLAHSQ---ASMSQSPVRQASSSSSSSSSSSALSVGQLVSNP 469
Score = 33.1 bits (74), Expect = 1.0
Identities = 42/190 (22%), Positives = 67/190 (35%), Gaps = 10/190 (5%)
Query: 431 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 490
P LS P Q Q Q+ PP P PQP + Q S V +G P L P P
Sbjct: 69 PALSDPGTPDQHQASQTHPPFP-VGPQPLLTAQQLASAV-AGVMPGGPPALNQPILIPFN 126
Query: 491 SPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMI 550
Q + P T + + AG Q L L+ ++ L+ +
Sbjct: 127 MAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQL 186
Query: 551 NKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVP 610
+ + + ++ S + P+ + P ++ Q+ L+ P PP P
Sbjct: 187 QQQQQQQQQQPPPSTNQH-----PQPAPQAPSQSQQQ---PLQPTPPQQPPPASQQPPAP 238
Query: 611 PTKQQYLCQP 620
++ Q QP
Sbjct: 239 TSQLQQAPQP 248
>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 89.0 bits (219), Expect = 2e-17
Identities = 91/324 (28%), Positives = 133/324 (41%), Gaps = 51/324 (15%)
Query: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A
Sbjct: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
Query: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
+ + L PP QPQQP + N S L + L+ Q L G +
Sbjct: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
Query: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398
PP + A + + + + A + Q+ P +Q + +
Sbjct: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159
Query: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQ 453
PP V PS GR P Q S SS +P ++ + Q+MP PP+
Sbjct: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPE 213
Query: 454 PSPQPGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS---- 505
S + +P + P P + P+P P+P + S + A+ ++ P+
Sbjct: 214 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 273
Query: 506 PGPLNTPVNPSSVMSPAGSSQAEE 529
PG L P + M+ +Q +
Sbjct: 274 PGQLQVKAQPQARMTVPKQTQTPD 297
Score = 76.3 bits (186), Expect = 1e-13
Identities = 65/197 (32%), Positives = 90/197 (45%), Gaps = 17/197 (8%)
Query: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVV----- 204
Q Q++ Q A +Q Q AL+ Q + Q + Q+ +Q Q Q +
Sbjct: 276 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT 335
Query: 205 QQQQQLQQQQQQQ---QHLIKLHHQNQQQIQQQ---QQQLQRIAQLQLQQQQQQQQQQQQ 258
Q Q +LQ+Q Q Q +HL+ Q Q Q+QQ+ Q+Q+Q Q Q Q +Q Q QQ
Sbjct: 336 QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ 395
Query: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH---QPPPQPQQPPVAQ--- 312
+ + Q QP +Q QP L +Q+Q + Q H QP QPQ+ P AQ
Sbjct: 396 EAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSV 455
Query: 313 NQPSQLPPQSQTQPLVS 329
P Q Q TQP VS
Sbjct: 456 QPPEQTHEQPHTQPQVS 472
Score = 72.0 bits (175), Expect = 2e-12
Identities = 83/282 (29%), Positives = 120/282 (42%), Gaps = 23/282 (8%)
Query: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194
AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++
Sbjct: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
Query: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
+ +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q
Sbjct: 306 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 364
Query: 255 QQQQQQQQALQAQPPIQ-----QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309
QQ+ + Q Q QP +Q Q P Q ++ L Q Q+ H QPP Q Q
Sbjct: 365 LQQEAEPQK-QVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQL 423
Query: 310 VAQNQPSQLPP-QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQT 368
Q Q P +Q QP V Q Q P + QPP +Q QP Q Q +
Sbjct: 424 QKQVQTQTYPQVHTQAQPSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVS 472
Query: 369 AVQTAQAAQMV-APGVQMITEAL-AQGGMHIRARFPPTTAVS 408
+ Q +V G++M +A+ A GGM P T VS
Sbjct: 473 LLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVS 514
Score = 66.2 bits (160), Expect = 1e-10
Identities = 100/437 (22%), Positives = 148/437 (33%), Gaps = 85/437 (19%)
Query: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215
QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ QQ Q L QQ
Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
Query: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL----------- 264
QQ L+ L N + + + QLQ Q L
Sbjct: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLR 123
Query: 265 ---QAQPPIQQPPMQQPQ---PPPSQALPQQLQQ-----------MHHTQHHQP--PPQP 305
A P + P + PQ P Q PQ +Q M+ +Q + PQ
Sbjct: 124 GYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQK 183
Query: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Q + P++ SQT P+ ++ G +P + P PP + +
Sbjct: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMD---TPEDQDLPPCPEDIAK 240
Query: 366 QQTA----VQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQP 421
++ + +A+++ A + SS P ++P
Sbjct: 241 EKRTPAPEPEPCEASELPA---------------------------KRLRSSEEPTEKEP 273
Query: 422 MAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG-QPS-SQPNSNVSSGPAPSPSS 479
Q+ + P P +Q QTP +P + P QP Q + V S P S
Sbjct: 274 PGQLQVKAQPQARMTVP-KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
Query: 480 FLPSPSPQPSQSPVTARTPQNFSVPS---PGPLNTPVNPSSVMSP--------AGSSQAE 528
P+ + T +P++ + L P + P G Q +
Sbjct: 333 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQ 392
Query: 529 EQQYLDKLKQLSKYIEP 545
QQ + LKQ+ ++P
Sbjct: 393 LQQEAEPLKQVQPQVQP 409
Score = 62.0 bits (149), Expect = 2e-09
Identities = 59/198 (29%), Positives = 80/198 (40%), Gaps = 39/198 (19%)
Query: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQ-QQQQQFQQQQQAALQQQQQQQQQQQ 188
P + + P T T L LQQ +Q Q QQ+ + Q+Q Q +Q Q Q +Q
Sbjct: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390
Query: 189 FQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQ 248
Q QQ A + +Q+Q Q Q Q H Q R QLQLQ+
Sbjct: 391 VQLQQEA---------EPLKQVQPQVQPQAH----------------SQPPRQVQLQLQK 425
Query: 249 QQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---P 305
Q Q Q Q Q QP +Q + PP+Q Q +Q H H QP P
Sbjct: 426 QVQTQTYPQVHTQ---------AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 476
Query: 306 QQPPVAQNQPS-QLPPQS 322
+Q PV + ++PP +
Sbjct: 477 EQTPVVVHVCGLEMPPDA 494
Score = 33.9 bits (76), Expect = 0.60
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 128 QPPPGTSGMAPHSMAVVSTATP--QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185
Q P P + + A P Q Q Q+Q A Q +Q Q Q Q+Q Q Q
Sbjct: 378 QVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQV----QTQTYP 433
Query: 186 QQQFQAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217
Q QAQ S Q+ Q VQ +Q +Q Q
Sbjct: 434 QVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
[Homo sapiens]
Length = 842
Score = 89.0 bits (219), Expect = 2e-17
Identities = 92/324 (28%), Positives = 132/324 (40%), Gaps = 51/324 (15%)
Query: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Q QQQ+QQQQQQLQ Q QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A
Sbjct: 5 QQQQQLQQQQQQLQ-------QLQQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
Query: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
+ + L PP QPQQP + N S L + L+ Q L G +
Sbjct: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
Query: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398
PP + A + + + + A + Q+ P +Q + +
Sbjct: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159
Query: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQ 453
PP V PS GR P Q S SS +P ++ + Q+MP PP+
Sbjct: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPE 213
Query: 454 PSPQPGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS---- 505
S + +P + P P + P+P P+P + S + A+ ++ P+
Sbjct: 214 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 273
Query: 506 PGPLNTPVNPSSVMSPAGSSQAEE 529
PG L P + M+ +Q +
Sbjct: 274 PGQLQVKAQPQARMTVPKQTQTPD 297
Score = 63.9 bits (154), Expect = 5e-10
Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194
AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++
Sbjct: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
Query: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
+ +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q
Sbjct: 306 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 364
Query: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308
QQ+ + Q Q QP + QP +Q + PP+Q Q +Q H H QP P+Q
Sbjct: 365 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 423
Query: 309 PVAQNQPS-QLPPQS 322
PV + ++PP +
Sbjct: 424 PVVVHVCGLEMPPDA 438
Score = 63.5 bits (153), Expect = 7e-10
Identities = 104/428 (24%), Positives = 140/428 (32%), Gaps = 103/428 (24%)
Query: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215
QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ QQ Q L QQ
Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
Query: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL----------- 264
QQ L+ L N + + + QLQ Q L
Sbjct: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLR 123
Query: 265 ---QAQPPIQQPPMQQPQ---PPPSQALPQQLQQ-----------MHHTQHHQP--PPQP 305
A P + P + PQ P Q PQ +Q M+ +Q + PQ
Sbjct: 124 GYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQK 183
Query: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQP---------------------- 343
Q + P++ SQT P+ ++ G +P
Sbjct: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKR 243
Query: 344 --------------PLKFVRA--PMVVQQPPVQPQVQQQQTAVQT-------------AQ 374
P K +R+ ++PP Q QV+ Q A T A
Sbjct: 244 TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 303
Query: 375 AAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLS 434
AQ++ + + AQ + R P T L +Q Q S L +
Sbjct: 304 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT-----QVQPKLQKQAQTQTSPEHLVLQQ 358
Query: 435 ---SPSPGQQVQTPQSMPPPPQPSPQPG-QPSSQPNSNVSSGPAPSPSSFLPSPSPQ--- 487
P Q+ + + + P QP QP P + VS P P + P PQ
Sbjct: 359 KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSL 417
Query: 488 --PSQSPV 493
P Q+PV
Sbjct: 418 LAPEQTPV 425
Score = 53.1 bits (126), Expect = 1e-06
Identities = 67/272 (24%), Positives = 100/272 (36%), Gaps = 30/272 (11%)
Query: 81 PMNALQSLTGGPAAGA----AGIGMPPRGPGQSLGGMGSL-------GAMGQPMSLSGQP 129
P QSL G P G + + R P + S + P+ P
Sbjct: 152 PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 211
Query: 130 PPGTSGMAPHSMAVVSTAT----PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185
P G+ A M P+ + ++ + + + + + ++ ++
Sbjct: 212 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK 271
Query: 186 QQQFQAQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHH---QNQQQIQQQQQQLQR 240
+ Q Q A Q V +Q Q L + + Q L + Q Q Q+Q Q Q
Sbjct: 272 EPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIP 331
Query: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Q+Q + Q+Q Q Q + + Q +Q P +QQ P Q PQ HTQ Q
Sbjct: 332 STDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ-PQLQQEAEPQKQVQPQV-----HTQ-AQ 384
Query: 301 PPPQPQQPPVAQ---NQPSQLPPQSQTQPLVS 329
P QPQ+ P AQ P Q Q TQP VS
Sbjct: 385 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 416
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 27/205 (13%)
Query: 209 QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP 268
QLQ + Q Q + + + + Q + + Q + Q Q Q Q Q Q + +
Sbjct: 276 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTD 334
Query: 269 PIQQPPMQ---QPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
QP +Q Q Q P + QQ Q Q P + QP V +Q Q
Sbjct: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV----------HTQAQ 384
Query: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQ 384
P V Q Q P + QPP +Q QP Q Q + + Q +V G++
Sbjct: 385 PSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLE 433
Query: 385 MITEAL-AQGGMHIRARFPPTTAVS 408
M +A+ A GGM P T VS
Sbjct: 434 MPPDAVEAGGGMEKTLPEPVGTQVS 458
>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 89.0 bits (219), Expect = 2e-17
Identities = 91/324 (28%), Positives = 133/324 (41%), Gaps = 51/324 (15%)
Query: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A
Sbjct: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
Query: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
+ + L PP QPQQP + N S L + L+ Q L G +
Sbjct: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
Query: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398
PP + A + + + + A + Q+ P +Q + +
Sbjct: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159
Query: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQ 453
PP V PS GR P Q S SS +P ++ + Q+MP PP+
Sbjct: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPE 213
Query: 454 PSPQPGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS---- 505
S + +P + P P + P+P P+P + S + A+ ++ P+
Sbjct: 214 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 273
Query: 506 PGPLNTPVNPSSVMSPAGSSQAEE 529
PG L P + M+ +Q +
Sbjct: 274 PGQLQVKAQPQARMTVPKQTQTPD 297
Score = 76.3 bits (186), Expect = 1e-13
Identities = 65/197 (32%), Positives = 90/197 (45%), Gaps = 17/197 (8%)
Query: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVV----- 204
Q Q++ Q A +Q Q AL+ Q + Q + Q+ +Q Q Q +
Sbjct: 276 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT 335
Query: 205 QQQQQLQQQQQQQ---QHLIKLHHQNQQQIQQQ---QQQLQRIAQLQLQQQQQQQQQQQQ 258
Q Q +LQ+Q Q Q +HL+ Q Q Q+QQ+ Q+Q+Q Q Q Q +Q Q QQ
Sbjct: 336 QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ 395
Query: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH---QPPPQPQQPPVAQ--- 312
+ + Q QP +Q QP L +Q+Q + Q H QP QPQ+ P AQ
Sbjct: 396 EAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSV 455
Query: 313 NQPSQLPPQSQTQPLVS 329
P Q Q TQP VS
Sbjct: 456 QPPEQTHEQPHTQPQVS 472
Score = 72.0 bits (175), Expect = 2e-12
Identities = 83/282 (29%), Positives = 120/282 (42%), Gaps = 23/282 (8%)
Query: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194
AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++
Sbjct: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
Query: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
+ +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q
Sbjct: 306 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 364
Query: 255 QQQQQQQQALQAQPPIQ-----QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309
QQ+ + Q Q QP +Q Q P Q ++ L Q Q+ H QPP Q Q
Sbjct: 365 LQQEAEPQK-QVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQL 423
Query: 310 VAQNQPSQLPP-QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQT 368
Q Q P +Q QP V Q Q P + QPP +Q QP Q Q +
Sbjct: 424 QKQVQTQTYPQVHTQAQPSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVS 472
Query: 369 AVQTAQAAQMV-APGVQMITEAL-AQGGMHIRARFPPTTAVS 408
+ Q +V G++M +A+ A GGM P T VS
Sbjct: 473 LLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVS 514
Score = 66.2 bits (160), Expect = 1e-10
Identities = 100/437 (22%), Positives = 148/437 (33%), Gaps = 85/437 (19%)
Query: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215
QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ QQ Q L QQ
Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
Query: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL----------- 264
QQ L+ L N + + + QLQ Q L
Sbjct: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLR 123
Query: 265 ---QAQPPIQQPPMQQPQ---PPPSQALPQQLQQ-----------MHHTQHHQP--PPQP 305
A P + P + PQ P Q PQ +Q M+ +Q + PQ
Sbjct: 124 GYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQK 183
Query: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Q + P++ SQT P+ ++ G +P + P PP + +
Sbjct: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMD---TPEDQDLPPCPEDIAK 240
Query: 366 QQTA----VQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQP 421
++ + +A+++ A + SS P ++P
Sbjct: 241 EKRTPAPEPEPCEASELPA---------------------------KRLRSSEEPTEKEP 273
Query: 422 MAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG-QPS-SQPNSNVSSGPAPSPSS 479
Q+ + P P +Q QTP +P + P QP Q + V S P S
Sbjct: 274 PGQLQVKAQPQARMTVP-KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
Query: 480 FLPSPSPQPSQSPVTARTPQNFSVPS---PGPLNTPVNPSSVMSP--------AGSSQAE 528
P+ + T +P++ + L P + P G Q +
Sbjct: 333 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQ 392
Query: 529 EQQYLDKLKQLSKYIEP 545
QQ + LKQ+ ++P
Sbjct: 393 LQQEAEPLKQVQPQVQP 409
Score = 62.0 bits (149), Expect = 2e-09
Identities = 59/198 (29%), Positives = 80/198 (40%), Gaps = 39/198 (19%)
Query: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQ-QQQQQFQQQQQAALQQQQQQQQQQQ 188
P + + P T T L LQQ +Q Q QQ+ + Q+Q Q +Q Q Q +Q
Sbjct: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390
Query: 189 FQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQ 248
Q QQ A + +Q+Q Q Q Q H Q R QLQLQ+
Sbjct: 391 VQLQQEA---------EPLKQVQPQVQPQAH----------------SQPPRQVQLQLQK 425
Query: 249 QQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---P 305
Q Q Q Q Q QP +Q + PP+Q Q +Q H H QP P
Sbjct: 426 QVQTQTYPQVHTQ---------AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 476
Query: 306 QQPPVAQNQPS-QLPPQS 322
+Q PV + ++PP +
Sbjct: 477 EQTPVVVHVCGLEMPPDA 494
Score = 33.9 bits (76), Expect = 0.60
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 128 QPPPGTSGMAPHSMAVVSTATP--QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185
Q P P + + A P Q Q Q+Q A Q +Q Q Q Q+Q Q Q
Sbjct: 378 QVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQV----QTQTYP 433
Query: 186 QQQFQAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217
Q QAQ S Q+ Q VQ +Q +Q Q
Sbjct: 434 QVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.125 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,783,973
Number of Sequences: 37866
Number of extensions: 2644479
Number of successful extensions: 103001
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1387
Number of HSP's successfully gapped in prelim test: 2250
Number of HSP's that attempted gapping in prelim test: 20686
Number of HSP's gapped (non-prelim): 31384
length of query: 788
length of database: 18,247,518
effective HSP length: 110
effective length of query: 678
effective length of database: 14,082,258
effective search space: 9547770924
effective search space used: 9547770924
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.