BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|51477690 tripartite motif-containing 6 and tripartite motif-containing 34 [Homo sapiens] (842 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 1718 0.0 gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 1010 0.0 gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 1010 0.0 gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 665 0.0 gi|117938316 tripartite motif-containing 22 [Homo sapiens] 618 e-177 gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 612 e-175 gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 536 e-152 gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] 524 e-148 gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens] 518 e-146 gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 384 e-106 gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 383 e-106 gi|15208660 tripartite motif protein 21 [Homo sapiens] 371 e-102 gi|37622899 ring finger protein 137 [Homo sapiens] 296 4e-80 gi|112421127 tripartite motif-containing 58 [Homo sapiens] 271 2e-72 gi|21630277 tripartite motif-containing 11 [Homo sapiens] 265 1e-70 gi|5454014 tripartite motif-containing 38 [Homo sapiens] 256 5e-68 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 239 1e-62 gi|22749269 ring finger protein 129 [Homo sapiens] 239 1e-62 gi|5730009 ret finger protein [Homo sapiens] 235 1e-61 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 229 6e-60 gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 207 3e-53 gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 207 3e-53 gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 193 5e-49 gi|157743261 tripartite motif-containing 75 [Homo sapiens] 192 1e-48 gi|31542779 tripartite motif family-like 1 [Homo sapiens] 191 2e-48 gi|169202375 PREDICTED: tripartite motif-containing protein 64B-... 190 4e-48 gi|210147600 tripartite motif-containing 64 [Homo sapiens] 189 9e-48 gi|239755486 PREDICTED: tripartite motif-containing protein 64C-... 187 3e-47 gi|239750044 PREDICTED: tripartite motif-containing protein 64C-... 187 3e-47 gi|239744355 PREDICTED: tripartite motif-containing protein 64C-... 187 3e-47 >gi|51477690 tripartite motif-containing 6 and tripartite motif-containing 34 [Homo sapiens] Length = 842 Score = 1718 bits (4450), Expect = 0.0 Identities = 842/842 (100%), Positives = 842/842 (100%) Query: 1 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH Sbjct: 1 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60 Query: 61 SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120 SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL Sbjct: 61 SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120 Query: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK Sbjct: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180 Query: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG Sbjct: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240 Query: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT Sbjct: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300 Query: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKIL 360 KLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKIL Sbjct: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKIL 360 Query: 361 LNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFE 420 LNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFE Sbjct: 361 LNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFE 420 Query: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR Sbjct: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480 Query: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE Sbjct: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540 Query: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM Sbjct: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600 Query: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 660 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN Sbjct: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 660 Query: 661 SVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVY 720 SVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVY Sbjct: 661 SVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVY 720 Query: 721 CRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSM 780 CRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSM Sbjct: 721 CRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSM 780 Query: 781 AVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP 840 AVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP Sbjct: 781 AVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP 840 Query: 841 SS 842 SS Sbjct: 841 SS 842 >gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 1010 bits (2612), Expect = 0.0 Identities = 488/488 (100%), Positives = 488/488 (100%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240 Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300 Query: 655 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 714 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 360 Query: 715 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 774 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE Sbjct: 361 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 420 Query: 775 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 834 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP Sbjct: 421 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 480 Query: 835 MTLCPPSS 842 MTLCPPSS Sbjct: 481 MTLCPPSS 488 Score = 376 bits (966), Expect = e-104 Identities = 188/300 (62%), Positives = 232/300 (77%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240 Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 Q STMELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YW Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300 >gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 1010 bits (2612), Expect = 0.0 Identities = 488/488 (100%), Positives = 488/488 (100%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240 Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300 Query: 655 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 714 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 360 Query: 715 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 774 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE Sbjct: 361 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 420 Query: 775 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 834 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP Sbjct: 421 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 480 Query: 835 MTLCPPSS 842 MTLCPPSS Sbjct: 481 MTLCPPSS 488 Score = 376 bits (966), Expect = e-104 Identities = 188/300 (62%), Positives = 232/300 (77%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240 Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 Q STMELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YW Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300 >gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] Length = 516 Score = 665 bits (1716), Expect = 0.0 Identities = 328/328 (100%), Positives = 328/328 (100%) Query: 1 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH Sbjct: 1 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60 Query: 61 SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120 SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL Sbjct: 61 SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120 Query: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK Sbjct: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180 Query: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG Sbjct: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240 Query: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT Sbjct: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300 Query: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYW 328 KLRSMFRAPDLKRMLRVCRELTDVQSYW Sbjct: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYW 328 Score = 563 bits (1452), Expect = e-160 Identities = 294/496 (59%), Positives = 361/496 (72%), Gaps = 12/496 (2%) Query: 353 SAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPV 412 + M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPV Sbjct: 27 ATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPV 86 Query: 413 CGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWL 472 C SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWL Sbjct: 87 CQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWL 146 Query: 473 CERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQT 532 CERSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ Sbjct: 147 CERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEP 206 Query: 533 ERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVE 592 ER RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E Sbjct: 207 ERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266 Query: 593 CRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRC 652 R Q STMELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ Sbjct: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQS 326 Query: 653 YWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWE 706 YWVDVTLN NLNLVL++++RQV +S P + Y+ VLGSQ+FSSGKHYWE Sbjct: 327 YWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWE 386 Query: 707 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFE 766 VDV+KKTAWILGV + + A + Y++Y+P GYWVIGLQ+ +Y +E Sbjct: 387 VDVAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYE 444 Query: 767 ESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826 +S S L LSM VPP RVGVFLDYEAG VSF+NVT+HG IY FSK F + PYF Sbjct: 445 DSSPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500 Query: 827 NPWNCPAPMTLCPPSS 842 NP NC PMTL PSS Sbjct: 501 NPCNCVIPMTLRRPSS 516 >gi|117938316 tripartite motif-containing 22 [Homo sapiens] Length = 498 Score = 618 bits (1594), Expect = e-177 Identities = 303/498 (60%), Positives = 376/498 (75%), Gaps = 10/498 (2%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 M + +++++EVTCPICLELLTEPLSLDCGHS C+ACIT KE+V G+SSCPVC Sbjct: 1 MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 + +L+ N+HLANIVER+KEVK+SP G+KRD+C+HHG+KL +FCKED KVICW+CE Sbjct: 61 TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 SQEH+GH T EV KECQEKLQ L+RL KE++EAEKLE DIR+E+T+WK +Q ER Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 Q+I F+++R IL+NEEQRELQ+LEE E LD A A D+LVQQ+Q LISD++ R Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240 Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654 + S++E+LQD+ +MK SE W LKKPK VSKKLK+VF PDLS MLQ+ +ELT V+ YW Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300 Query: 655 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN------YGVLGSQYFSSGKHYWEVD 708 VDV LN + N+ +S DQRQV +V F+ N +GV G QYFSSGK+YWEVD Sbjct: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD 360 Query: 709 VSKKTAWILGVYCRTYSRHMK----YVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 764 VS K AWILGV+ + S + + + N +Y++YRP +GYWVIGLQN C+Y Sbjct: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420 Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824 FE+S SSDP+VLTL MAVPPCR+GVFLDYEAGIVSFFNVT+HG+LIYKFS C FS+P YP Sbjct: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480 Query: 825 YFNPWNCPAPMTLCPPSS 842 YFNPWNC PMT+CPPSS Sbjct: 481 YFNPWNCLVPMTVCPPSS 498 Score = 369 bits (946), Expect = e-102 Identities = 181/300 (60%), Positives = 228/300 (76%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M V VDI +EVTCPICLELLTEPLS+DCGHSFCQACIT +ESVI GE SCPVCQ Sbjct: 1 MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 T +QPGNLRPNRHLANIV R++EV + P + K +C HG+KLQ+FC+EDGKVICW+CE Sbjct: 61 TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 SQEH+GH TF + EV +E QEK Q +L++L E+QEAEKL IR+++T+WKN ++ ER Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 +I FN++R ILD EQREL+KLE+ E L + A + LV Q Q LISDL+RR Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240 Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 +GS++E+LQDV DV +RSE WTL+KP+++ KL+S+FR PDL ML+V +ELTDVQ YW Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300 >gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] Length = 488 Score = 612 bits (1579), Expect = e-175 Identities = 300/300 (100%), Positives = 300/300 (100%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ Sbjct: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE Sbjct: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240 Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300 Score = 563 bits (1451), Expect = e-160 Identities = 294/494 (59%), Positives = 360/494 (72%), Gaps = 12/494 (2%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC Sbjct: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE Sbjct: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240 Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654 Q STMELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YW Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300 Query: 655 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVD 708 VDVTLN NLNLVL++++RQV +S P + Y+ VLGSQ+FSSGKHYWEVD Sbjct: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360 Query: 709 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 768 V+KKTAWILGV + + A + Y++Y+P GYWVIGLQ+ +Y +E+S Sbjct: 361 VAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 418 Query: 769 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 828 S L LSM VPP RVGVFLDYEAG VSF+NVT+HG IY FSK F + PYFNP Sbjct: 419 SPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474 Query: 829 WNCPAPMTLCPPSS 842 NC PMTL PSS Sbjct: 475 CNCVIPMTLRRPSS 488 >gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo sapiens] Length = 493 Score = 536 bits (1382), Expect = e-152 Identities = 285/504 (56%), Positives = 359/504 (71%), Gaps = 27/504 (5%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++ G +SSCPVC Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 ISY E+++ N+H+AN+VE+L+EVKLSP+ G+K D C HGEKLLLFC+ED KVICWLCE Sbjct: 60 ISYQPENIRPNRHVANLVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 RSQEHRGHHT TEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++ Sbjct: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 + +F+QLR IL+ EE ELQ LE+EE+ L +E E+VQQ Q +RELISD+E R Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238 Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654 Q S MELLQ + G++K +E LKKP+ K + VF APDL ML++FRELT VR YW Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298 Query: 655 VDVTLNSVNLNLNLVLSEDQRQVIS-----------VPIWPFQCYNY--GVLGSQYFSSG 701 VDVT+ N++ V+SED+RQV S F +NY G+LGSQ +SG Sbjct: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357 Query: 702 KHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 761 KHYWEVDVSKKTAWILGV C + + + N Y+P +GYWVIGL+ K Sbjct: 358 KHYWEVDVSKKTAWILGV-CAGFQPDAMCNIEKNEN-------YQPKYGYWVIGLEEGVK 409 Query: 762 YGVFEES---LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 818 F++S S P ++ LS+ + P RVGVFLDYEA VSFFN+T+HG LIYKFS C F Sbjct: 410 CSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSF 469 Query: 819 SQPVYPYFNPWNCPAPMTLCPPSS 842 SQPV+PY NP C PMTLC PSS Sbjct: 470 SQPVFPYLNPRKCGVPMTLCSPSS 493 Score = 380 bits (975), Expect = e-105 Identities = 188/300 (62%), Positives = 232/300 (77%), Gaps = 2/300 (0%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+ Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 SYQP N+RPNRH+AN+V +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE Sbjct: 60 ISYQPENIRPNRHVANLVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 RSQEHRGHHTF EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++ Sbjct: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 + +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238 Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298 >gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] Length = 270 Score = 524 bits (1349), Expect = e-148 Identities = 259/262 (98%), Positives = 260/262 (99%), Gaps = 1/262 (0%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240 Query: 595 SQWSTMELLQDMSGIMKWSEIW 616 SQWSTMELLQDMSGIMKW +W Sbjct: 241 SQWSTMELLQDMSGIMKWC-VW 261 Score = 328 bits (840), Expect = 2e-89 Identities = 165/255 (64%), Positives = 199/255 (78%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V G+ SCPVC Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 SY +L+ N+HLANIV RL+EV L P K LC HGEKL LFC+ED KVICWLCE Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 RSQEHRGHHT L EEV +E QEK Q LK+LK EE+EAEKL A IRE+KTSWK Q++ ER Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 RIQTEF+QLR+IL+ EQREL++LE+EEKK L EAE++LV Q Q +RELISD+E R Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240 Query: 269 CQGSTMELLQDVSDV 283 Q STMELLQD+S + Sbjct: 241 SQWSTMELLQDMSGI 255 >gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens] Length = 243 Score = 518 bits (1333), Expect = e-146 Identities = 243/243 (100%), Positives = 243/243 (100%) Query: 600 MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 659 MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL Sbjct: 1 MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 60 Query: 660 NSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV 719 NSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV Sbjct: 61 NSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV 120 Query: 720 YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLS 779 YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLS Sbjct: 121 YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLS 180 Query: 780 MAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP 839 MAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP Sbjct: 181 MAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP 240 Query: 840 PSS 842 PSS Sbjct: 241 PSS 243 Score = 67.0 bits (162), Expect = 7e-11 Identities = 30/55 (54%), Positives = 42/55 (76%) Query: 274 MELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 MELLQD+S + + SE W L+KP+ + KL+++F APDL RML++ RELT V+ YW Sbjct: 1 MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 55 >gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo sapiens] Length = 347 Score = 384 bits (985), Expect = e-106 Identities = 191/305 (62%), Positives = 235/305 (77%), Gaps = 2/305 (0%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+ Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 SYQP N+RPNRH+ANIV +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE Sbjct: 60 ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++ Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 + +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238 Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298 Query: 329 AIQGS 333 + S Sbjct: 299 GKEKS 303 Score = 366 bits (940), Expect = e-101 Identities = 184/300 (61%), Positives = 234/300 (78%), Gaps = 2/300 (0%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++ G +SSCPVC Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 ISY E+++ N+H+ANIVE+L+EVKLSP+ G+K D C HGEKLLLFC+ED KVICWLCE Sbjct: 60 ISYQPENIRPNRHVANIVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 RSQEHRGHHT LTEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++ Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 + +F+QLR IL+ EE ELQ LE+EE+ L +E E+VQQ Q +RELISD+E R Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238 Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654 Q S MELLQ + G++K +E LKKP+ K + VF APDL ML++FRELT VR YW Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298 >gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo sapiens] Length = 326 Score = 383 bits (984), Expect = e-106 Identities = 190/300 (63%), Positives = 233/300 (77%), Gaps = 2/300 (0%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+ Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59 Query: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148 SYQP N+RPNRH+ANIV +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE Sbjct: 60 ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118 Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208 RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++ Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178 Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268 + +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238 Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328 QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298 Score = 366 bits (940), Expect = e-101 Identities = 184/300 (61%), Positives = 234/300 (78%), Gaps = 2/300 (0%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++ G +SSCPVC Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474 ISY E+++ N+H+ANIVE+L+EVKLSP+ G+K D C HGEKLLLFC+ED KVICWLCE Sbjct: 60 ISYQPENIRPNRHVANIVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118 Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534 RSQEHRGHHT LTEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++ Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178 Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594 + +F+QLR IL+ EE ELQ LE+EE+ L +E E+VQQ Q +RELISD+E R Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238 Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654 Q S MELLQ + G++K +E LKKP+ K + VF APDL ML++FRELT VR YW Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298 >gi|15208660 tripartite motif protein 21 [Homo sapiens] Length = 475 Score = 371 bits (953), Expect = e-102 Identities = 213/500 (42%), Positives = 301/500 (60%), Gaps = 51/500 (10%) Query: 355 MASKILLNVQ-EEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVC 413 MAS L + EEVTCPICL+ EP+S++CGHS C+ CI+ K GG S CPVC Sbjct: 1 MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGK------GGGSVCPVC 54 Query: 414 GISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLC 473 + ++L+ N+ LAN+V LKE+ G + + C HGE+L LFC++D K +CW+C Sbjct: 55 RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVC 114 Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533 +S++HR H V EE +E QEKLQ L L++++E AEKLE +I ++ WK V+T+ Sbjct: 115 AQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ 174 Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593 + RI EF Q ++ L EEQR+LQ LE++E++ L E E +L QQ Q ++ELIS+++ Sbjct: 175 KSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDR 234 Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653 R S +ELLQ++ +++ SE W LK + S +L++V H P L +ML R Sbjct: 235 RCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML---------RTC 285 Query: 654 WVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG-VLGSQYFSSGKHYWE 706 V +TL+ N L+LSED+RQV S+P + +Y VLG+Q+F SGKHYWE Sbjct: 286 AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWE 345 Query: 707 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKY--GV 764 VDV+ K AW LGV CR R + + + G+W I L NK KY G Sbjct: 346 VDVTGKEAWDLGV-CRDSVRRKGHFLLSSKS------------GFWTIWLWNKQKYEAGT 392 Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824 + ++ L + VPPC+VG+FLDYEAG+VSF+N+T HGSLIY FS+C F+ P+ P Sbjct: 393 YPQT--------PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRP 444 Query: 825 YFNP-----WNCPAPMTLCP 839 +F+P AP+TLCP Sbjct: 445 FFSPGFNDGGKNTAPLTLCP 464 Score = 272 bits (695), Expect = 1e-72 Identities = 135/280 (48%), Positives = 187/280 (66%), Gaps = 6/280 (2%) Query: 39 EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRP 98 EEVTCPICL+ EP+SI+CGHSFCQ CI S +G+ G CPVC+ + NLRP Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65 Query: 99 NRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHT 158 NR LAN+V L+E+ + + CA HGE+L LFC++DGK +CW+C +S++HR H Sbjct: 66 NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125 Query: 159 FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQL 218 +EE AQEYQEK Q +L +L+ +++ AEKL I K+ WK +E ++ RI EF Q Sbjct: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185 Query: 219 RNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQ 278 +N L EQR+L++LE++E++ LRI+ E E L Q+Q+L+ELIS+L+RRC S +ELLQ Sbjct: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245 Query: 279 DVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVC 318 +V V ERSE W L+ + +LRS+ P LK+MLR C Sbjct: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTC 285 >gi|37622899 ring finger protein 137 [Homo sapiens] Length = 485 Score = 296 bits (759), Expect = 4e-80 Identities = 179/498 (35%), Positives = 270/498 (54%), Gaps = 50/498 (10%) Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422 + EEV CPIC+ L EP+S+DCGHS C +C++ + S +CP+C +L Sbjct: 10 IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNL 69 Query: 423 QANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH 482 + N LAN+VE+++ ++L P G K DLC+ HGEKL +FCKED ++C C +S EH H Sbjct: 70 RPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAH 129 Query: 483 HTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFD 542 V E+V E + +L L+ LKKE+EEA KLE R+ +WK QV+T +Q I EF+ Sbjct: 130 SVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFE 189 Query: 543 QLRSILNN----------EEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVE 592 + + +L E L L+ E +T+ K EL+QQ Q++ +I++++ Sbjct: 190 KYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249 Query: 593 CRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRC 652 RSQ +LQD+ ++ S+ W L++P+ +S +LKT L +L + Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREIL---------KT 300 Query: 653 YWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG-VLGSQYFSSGKHYW 705 Y DV L+ L++SED+++V +P P + Y Y VLGSQ SSG+HYW Sbjct: 301 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYW 360 Query: 706 EVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVF 765 EV+V ++ W LGV + R ++ +Y P +G+WVI L+ +Y Sbjct: 361 EVEVGDRSEWGLGVCKQNVDR-----------KEVVYLS--PHYGFWVIRLRKGNEY--- 404 Query: 766 EESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPY 825 + E LS+ VPP RVG+F+DYEA +SF+NVT GS I+ F + F + PY Sbjct: 405 ---RAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPY 461 Query: 826 FNP-----WNCPAPMTLC 838 F+P N AP+ +C Sbjct: 462 FSPCYSIGTNNTAPLAIC 479 Score = 210 bits (534), Expect = 5e-54 Identities = 108/290 (37%), Positives = 173/290 (59%), Gaps = 10/290 (3%) Query: 37 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96 I EEV CPIC+ L EP+SIDCGHSFC +C++ Q +CP+C+ QP NL Sbjct: 10 IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNL 69 Query: 97 RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 156 RPN LAN+V ++R + L PG LK LC HGEKL++FC+ED ++C C +S EH H Sbjct: 70 RPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAH 129 Query: 157 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 216 +E+VA EY+ + E+L+ LK E++EA KL R++ +WK Q+E + I EF Sbjct: 130 SVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFE 189 Query: 217 QLRNILDRVE----------QRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266 + + +L++ + L L++E + ++ +E ++L+ Q+Q L +I++L+ Sbjct: 190 KYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249 Query: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316 R Q +LQD+ +V RS+ W+L++PE + +L++ R L+ +L+ Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILK 299 >gi|112421127 tripartite motif-containing 58 [Homo sapiens] Length = 486 Score = 271 bits (693), Expect = 2e-72 Identities = 169/487 (34%), Positives = 259/487 (53%), Gaps = 41/487 (8%) Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422 ++E+ CP+CL+ L EP+S+DCGHS C CI+ +++ + GG +CP C + Sbjct: 10 LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69 Query: 423 QANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH 482 + N+ LA +VE ++ + L G +R C HGE L FC+ED +CW+C+ EHR H Sbjct: 70 RPNRQLAGLVESVRRLGLGAGPGARR--CARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127 Query: 483 HTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFD 542 T +E Q KLQ L+ ++KE E+A EA++ ++ WK +V+ +RQR + EF+ Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187 Query: 543 QLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTMEL 602 + R L EEQR+L+RLE EE+ TL + E++ LVQQ + ++EL +++ R Q + L Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247 Query: 603 LQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNSV 662 L+ + G++ S+ + + + +LKT P +L+ F+ VDV L+ Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQ---------VDVKLDPA 298 Query: 663 NLNLNLVLSEDQRQVISVPIW---PFQCYNYG----VLGSQYFSSGKHYWEVDVSKKTAW 715 + +L+L+ D R V W P + +LG Q FSSG+HYWEV V + W Sbjct: 299 TAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEW 358 Query: 716 ILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEV 775 LGV T R + T P G W + L +Y V + P V Sbjct: 359 GLGVCQDTLPRKGE-------------TTPSPENGVWALWLLKGNEYMVL-----ASPSV 400 Query: 776 LTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPM 835 L + P C +G+FLDYEAG +SF+NVT GS IY F++ FS + PYF + C A Sbjct: 401 PLLQLESPRC-IGIFLDYEAGEISFYNVTD-GSYIYTFNQ-LFSGLLRPYF--FICDATP 455 Query: 836 TLCPPSS 842 + PP++ Sbjct: 456 LILPPTT 462 Score = 217 bits (553), Expect = 3e-56 Identities = 108/280 (38%), Positives = 169/280 (60%), Gaps = 2/280 (0%) Query: 37 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96 +RE+ CP+CL+ L EP+S+DCGHSFC CI+ +S Q G +CP C+ ++P Sbjct: 10 LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69 Query: 97 RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 156 RPNR LA +V +R + LG G + CA HGE L FC+ED +CW+C+ EHR H Sbjct: 70 RPNRQLAGLVESVRRLGLGAGPGARR--CARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127 Query: 157 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 216 T ++E A YQ K Q +L+ ++ E ++A A + +K WK ++E +R R + EF Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187 Query: 217 QLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMEL 276 + R L + EQR+L++LE EE+ L+ + E+++ LV Q+++L+EL +L+ RCQ + L Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247 Query: 277 LQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316 L+ V V RS+ T + E +P +L++ P + +LR Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLR 287 >gi|21630277 tripartite motif-containing 11 [Homo sapiens] Length = 468 Score = 265 bits (677), Expect = 1e-70 Identities = 170/494 (34%), Positives = 262/494 (53%), Gaps = 48/494 (9%) Query: 356 ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGI 415 A + N+QEE TC ICL+ T+P+ DCGH+ CR CI + G +CP C Sbjct: 3 APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPECRE 58 Query: 416 SYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCER 475 +L+ N+ LA + E + +L P + + +C H E L FC ++ +++C CER Sbjct: 59 LSPQRNLRPNRPLAKMAEMAR--RLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACER 116 Query: 476 SQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQ 535 S EH H ++ ++ + KL+ L+ L+K+ ++A +A E W+ V+++RQ Sbjct: 117 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ 176 Query: 536 RIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRS 595 + EF++LR +L EEQ+ LQRLEEEE + L + E L QQ + ELI+++E R Sbjct: 177 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC 236 Query: 596 QWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV 655 Q + LLQD+ ++ + +L+ P++V +L+TV P L L+ FR Sbjct: 237 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG--------- 287 Query: 656 DVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG--VLGSQYFSSGKHYWEV 707 DVTL+ N L+LSED+R V ++P P + ++ G VLG + F+SG+HYWEV Sbjct: 288 DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSP-ERFDPGPCVLGQERFTSGRHYWEV 346 Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767 +V +T+W LGV CR + N G+W++ VF Sbjct: 347 EVGDRTSWALGV-CRENVNRKEKGELSAGN------------GFWIL---------VFLG 384 Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFN 827 S + E + PP RVG+FLDYEAG +SF++ T GSL++ F + FS + P F+ Sbjct: 385 SYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFS 443 Query: 828 PW-NCPAPMTLCPP 840 P + P PMT+C P Sbjct: 444 PLSSSPTPMTICRP 457 Score = 183 bits (465), Expect = 5e-46 Identities = 105/289 (36%), Positives = 159/289 (55%), Gaps = 7/289 (2%) Query: 29 MTSPVL-VDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVC 87 M +P L +++EE TC ICL+ T+P+ DCGH+FC+ CI R EG +CP C Sbjct: 1 MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPEC 56 Query: 88 QTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLC 147 + NLRPNR LA + R L P + +C H E L FC ++ +++C C Sbjct: 57 RELSPQRNLRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114 Query: 148 ERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE 207 ERS EH H +++ A++ + K ++SL+ L+ + Q+A A E W+ +E + Sbjct: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ 174 Query: 208 RCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLER 267 R + EF +LR +L EQ+ L++LE+EE + L + E L Q+ L ELI++LE Sbjct: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234 Query: 268 RCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316 RCQ + LLQD+ D R + L+ PE +P +LR++ R P L LR Sbjct: 235 RCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLR 283 >gi|5454014 tripartite motif-containing 38 [Homo sapiens] Length = 465 Score = 256 bits (655), Expect = 5e-68 Identities = 166/491 (33%), Positives = 256/491 (52%), Gaps = 50/491 (10%) Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSS--CPVCGISYSFE 420 + EE TC ICL L+T P+S++CGHS C CIT K + + CP C + + Sbjct: 10 MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69 Query: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480 L+ N+ L +++E LKE C+ HGE+ LFC+++ ++ICW CER+ +H+ Sbjct: 70 SLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICWRCERAPQHK 122 Query: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540 GH T L E+V + +EKLQ + +LK+ E+ + + T WK +VQ +RQ+I+++ Sbjct: 123 GHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSD 182 Query: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600 F L+ L+ EE+ L RLE+EE++TL + + E L + ++ I ++E + Q S Sbjct: 183 FKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQ 242 Query: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 660 +LLQ+++ + S +L+ + VS +L T+ + L F +R + V VTL+ Sbjct: 243 KLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKL-----YFDVKKMLRSHQVSVTLD 297 Query: 661 SVNLNLNLVLSEDQRQVI-----------SVPIWPFQCYNYGVLGSQYFSSGKHYWEVDV 709 + L+LSED+RQV S F C VLG + F+SG+ Y+EVDV Sbjct: 298 PDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC----VLGCEGFTSGRRYFEVDV 353 Query: 710 SKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESL 769 + T W LGV R K P G+W + L K Y +L Sbjct: 354 GEGTGWDLGVCMENVQR-------------GTGMKQEPQSGFWTLRLCKKKGY----VAL 396 Query: 770 SSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW 829 +S P +L + P VG+FLDYEAG+VSF+N + G I+ F K FS + PYF + Sbjct: 397 TSPP--TSLHLHEQPLLVGIFLDYEAGVVSFYNGNT-GCHIFTFPKASFSDTLRPYFQVY 453 Query: 830 NCPAPMTLCPP 840 +P+ L PP Sbjct: 454 QY-SPLFLPPP 463 Score = 199 bits (507), Expect = 7e-51 Identities = 106/285 (37%), Positives = 168/285 (58%), Gaps = 15/285 (5%) Query: 39 EEVTCPICLELLTEPLSIDCGHSFCQACITP---NGRESVIGQEGERSCPVCQTSYQPGN 95 EE TC ICL L+T P+SI+CGHS+C CIT N + + QE CP C+ + + Sbjct: 12 EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCCPQCRAPFHMDS 70 Query: 96 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155 LRPN+ L +++ L+E + + C +HGE+ LFC+++G++ICW CER+ +H+G Sbjct: 71 LRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKG 123 Query: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215 H T LVE+V Q Y+EK Q+++ KLK E + + T WK +++ +R +I+++F Sbjct: 124 HTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183 Query: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275 L+ L E+ L +LE+EE++ L + + E L ++ L+ I +LE +CQGS + Sbjct: 184 KNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQK 243 Query: 276 LLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLR 316 LLQ+V+D RS L EA+ +L +M D+K+MLR Sbjct: 244 LLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR 288 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 239 bits (609), Expect = 1e-62 Identities = 163/503 (32%), Positives = 264/503 (52%), Gaps = 42/503 (8%) Query: 352 SSAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCP 411 S+A + L N+Q E +C +CLE L EP+ ++CGH+ C+ACIT ++ CP Sbjct: 12 SAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDF----PCP 67 Query: 412 VCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICW 471 VC + + L+ N+ L ++VE K+++ + LC H E L LFC ED++ +C Sbjct: 68 VCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCL 127 Query: 472 LCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQ 531 +C S HR H V ++ +E +EKLQ L+ L+++ +E + ++ ++ K V+ Sbjct: 128 ICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVE 187 Query: 532 TERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDV 591 + RQ+I EF++L L+ E+Q L RLEEEE+ L + E L +++ + L ++V Sbjct: 188 SRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEV 247 Query: 592 ECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVR 651 E + S E+L+D+ ++ E ++K ++ S ++ + + R R++ ++ Sbjct: 248 EGKCLQSGFEMLKDVKSTLEKCE--KVKTMEVTSVSIELEKNFSNFPRQYFALRKI--LK 303 Query: 652 CYWVDVTLNSVNLNLNLVLSEDQRQVISV-------PIWPFQCYNYG-VLGSQYFSSGKH 703 DVTL+ + NLVLSED++ V V P P + Y VL ++ F+SG+H Sbjct: 304 QLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRH 363 Query: 704 YWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG 763 YWEV+V KT W +G V R +R+ T P GYW + L N KY Sbjct: 364 YWEVEVGDKTHWAVG------------VCRDSVSRKGELTPL-PETGYWRVRLWNGDKYA 410 Query: 764 VFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVY 823 ++ L + V P RVG+FLDYEAG +SF+NVT S IY F+ F++ ++ Sbjct: 411 ------ATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDR-SHIYTFTD-TFTEKLW 462 Query: 824 PYFNPW-----NCPAPMTLCPPS 841 P F P AP+T+ PP+ Sbjct: 463 PLFYPGIRAGRKNAAPLTIRPPT 485 Score = 163 bits (413), Expect = 5e-40 Identities = 93/269 (34%), Positives = 147/269 (54%), Gaps = 6/269 (2%) Query: 20 QAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE 79 +AGA A T+ L +++ E +C +CLE L EP+ I+CGH+FC+ACIT + E Sbjct: 8 EAGAS--AASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----E 61 Query: 80 GERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQED 139 + CPVC+ + + +LRPNR L ++V +++ K LC H E L LFC ED Sbjct: 62 RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYED 121 Query: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199 + +C +C S HR H +++ QEY+EK Q+ L+ L+ + QE + + +K Sbjct: 122 QEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGE 181 Query: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259 K +E R +I EF +L LD +Q L +LE+EE+ L+ + E L + + L Sbjct: 182 LKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLA 241 Query: 260 ELISDLERRCQGSTMELLQDVSDVTERSE 288 L +++E +C S E+L+DV E+ E Sbjct: 242 HLAAEVEGKCLQSGFEMLKDVKSTLEKCE 270 >gi|22749269 ring finger protein 129 [Homo sapiens] Length = 471 Score = 239 bits (609), Expect = 1e-62 Identities = 158/497 (31%), Positives = 259/497 (52%), Gaps = 51/497 (10%) Query: 360 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 419 L+N+QEE +CPICLE L +P++++CGH+ CR+C++VS K+ + CPVC + + Sbjct: 7 LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKD----LDDTFPCPVCRFCFPY 62 Query: 420 EHLQANQHLANIVERLKEVKLSPDNGKKRD---LCDHHGEKLLLFCKEDRKVICWLCERS 476 + + N L N+ E K++++ K++ +C+ H + L LFC +D +++C C S Sbjct: 63 KSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFS 122 Query: 477 QEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQR 536 +H+ H+ ++ +E L+ L+ L+ E EK+ + K +V+ +R+ Sbjct: 123 TKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREE 182 Query: 537 IQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQ 596 I +EF+Q+R L NE++ L+++++EE L K E EL ++ L+ +VE +S Sbjct: 183 INSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSV 242 Query: 597 WSTMELLQDMSGIMKWSEIWRLKKPKMVSKKL-KTVFHAP----DLSRMLQMFRELTAVR 651 S +ELL + + LK P++ S +L K F P L R+++ F+ Sbjct: 243 QSNLELLTQAKSM--HHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPFQ------ 294 Query: 652 CYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN-------YGVLGSQYFSSGKHY 704 VDV L+ + L++SED++ V CY+ VLGSQ FSSG+HY Sbjct: 295 ---VDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHY 351 Query: 705 WEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 764 WEV+V K WILG V + C R N + L G+W IG K Y Sbjct: 352 WEVEVGNKPKWILG------------VCQDCLLR-NWQDQPSVLGGFWAIGRYMKSGY-- 396 Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824 ++S P+ L V P ++G+FLDYE G +SF+N+ S++Y F+ CF++ V+P Sbjct: 397 ----VASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDR-SILYTFND-CFTEAVWP 450 Query: 825 YFNPWNCPAPMTLCPPS 841 YF P+ +C S Sbjct: 451 YFYTGTDSEPLKICSVS 467 Score = 137 bits (346), Expect = 3e-32 Identities = 76/272 (27%), Positives = 146/272 (53%), Gaps = 9/272 (3%) Query: 34 LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93 LV+++EE +CPICLE L +P++I+CGH+FC++C++ + ++ + CPVC+ + Sbjct: 7 LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDL----DDTFPCPVCRFCFPY 62 Query: 94 GNLRPNRHLANIVRRLREVVLGPGK---QLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150 + R N L N+ +++ + K Q + +C H + L LFC +D +++C C S Sbjct: 63 KSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFS 122 Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210 +H+ H+ +++ A ++E + SL+ L+N + EK+ K K ++E +R Sbjct: 123 TKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREE 182 Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270 I +EF Q+R L ++ L++++ EE L + E +L +L+ L+ ++E + Sbjct: 183 INSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSV 242 Query: 271 GSTMELLQDVSDVTERSEFWTLRKPEALPTKL 302 S +ELL + ++ L+ PE +L Sbjct: 243 QSNLELLTQAKSM--HHKYQNLKCPELFSFRL 272 >gi|5730009 ret finger protein [Homo sapiens] Length = 513 Score = 235 bits (600), Expect = 1e-61 Identities = 164/512 (32%), Positives = 253/512 (49%), Gaps = 61/512 (11%) Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422 +Q+E TCP+CL+ EP+ LDCGH++C AC+ A T++ SCP C ++ H+ Sbjct: 10 LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNV----SCPQCRETFPQRHM 65 Query: 423 QANQHLANIVERLKEVKLSPDNGKKRDL--CDHHGEKLLLFCKEDRKVICWLCERSQEHR 480 + N+HLAN+ + +K+++ +G ++ C+ H E L L+C+ED+ IC +C+RS+EHR Sbjct: 66 RPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHR 125 Query: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540 GH + EE + +E++Q L LK+ ++ ++ A + + Q ER++I E Sbjct: 126 GHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWE 185 Query: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600 F+QL L E R L RLEE + + A + + LI+ +E + Q T Sbjct: 186 FEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTR 245 Query: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFH----------------APDLSRMLQMF 644 ELLQD+ + +E R+ +P + L+ H + ++ Sbjct: 246 ELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKI 305 Query: 645 RELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWP-----FQCYNYGVL 693 +EL + Y VDVTL+ +L+LS++ RQV +P P F C VL Sbjct: 306 QELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC----VL 361 Query: 694 GSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWV 753 GS F +G+HYWEV+V K W +GV C V R+ P G+W Sbjct: 362 GSPCFIAGRHYWEVEVGDKAKWTIGV-CE------DSVCRKGG------VTSAPQNGFWA 408 Query: 754 IGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKF 813 + L YG +L+S + L + P RVG+FLDY+AG VSF+NVT + F Sbjct: 409 VSLW----YGKEYWALTS--PMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTF 461 Query: 814 SKCCFSQPVYPYF----NPWNCPAPMTLCPPS 841 S F PV PYF + AP+ +CP S Sbjct: 462 SHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493 Score = 159 bits (402), Expect = 1e-38 Identities = 94/271 (34%), Positives = 145/271 (53%), Gaps = 10/271 (3%) Query: 37 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96 +++E TCP+CL+ EP+ +DCGH+ C AC+ + E SCP C+ ++ ++ Sbjct: 10 LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQCRETFPQRHM 65 Query: 97 RPNRHLANI---VRRLR-EVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 152 RPNRHLAN+ V++LR E GPG ++ +C H E L+L+C+ED IC +C+RS+E Sbjct: 66 RPNRHLANVTQLVKQLRTERPSGPGGEMG--VCEKHREPLKLYCEEDQMPICVVCDRSRE 123 Query: 153 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 212 HRGH +EE + ++E+ Q L LK + ++ A + + + + ER +I Sbjct: 124 HRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIV 183 Query: 213 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGS 272 EF QL + L E R L +LE+ + I A L LI+ LE + Q Sbjct: 184 WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQP 243 Query: 273 TMELLQDVSDVTERSEFWTLRKPEALPTKLR 303 T ELLQD+ D R+E + +P P L+ Sbjct: 244 TRELLQDIGDTLSRAERIRIPEPWITPPDLQ 274 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 229 bits (585), Expect = 6e-60 Identities = 165/529 (31%), Positives = 264/529 (49%), Gaps = 64/529 (12%) Query: 352 SSAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCP 411 S+A + L N+Q E +C +CLE L EP+ ++CGH+ C+ACIT ++ CP Sbjct: 12 SAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDF----PCP 67 Query: 412 VCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICW 471 VC + + L+ N+ L ++VE K+++ + LC H E L LFC ED++ +C Sbjct: 68 VCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCL 127 Query: 472 LCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQ 531 +C S HR H V ++ +E +EKLQ L+ L+++ +E + ++ ++ K V+ Sbjct: 128 ICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVE 187 Query: 532 TERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDV 591 + RQ+I EF++L L+ E+Q L RLEEEE+ L + E L +++ + L ++V Sbjct: 188 SRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEV 247 Query: 592 ECRSQWSTMELLQDMSGIMKWS-------------------------EIWRLKKPKMVSK 626 E + S E+L+D+ ++ + EI R +K K + Sbjct: 248 EGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEV 307 Query: 627 KLKTVFHAPDLSRMLQMFRELTAVRCYWV-DVTLNSVNLNLNLVLSEDQRQVISV----- 680 ++ + S + + L + + DVTL+ + NLVLSED++ V V Sbjct: 308 TSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLR 367 Query: 681 --PIWPFQCYNYG-VLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCAN 737 P P + Y VL ++ F+SG+HYWEV+V KT W +G V R + Sbjct: 368 DLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVG------------VCRDSVS 415 Query: 738 RQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGI 797 R+ T P GYW + L N KY ++ L + V P RVG+FLDYEAG Sbjct: 416 RKGELTPL-PETGYWRVRLWNGDKYA------ATTTPFTPLHIKVKPKRVGIFLDYEAGT 468 Query: 798 VSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW-----NCPAPMTLCPPS 841 +SF+NVT S IY F+ F++ ++P F P AP+T+ PP+ Sbjct: 469 LSFYNVTDR-SHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRPPT 515 Score = 162 bits (410), Expect = 1e-39 Identities = 92/268 (34%), Positives = 147/268 (54%), Gaps = 6/268 (2%) Query: 20 QAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE 79 +AGA A T+ L +++ E +C +CLE L EP+ I+CGH+FC+ACIT + E Sbjct: 8 EAGAS--AASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----E 61 Query: 80 GERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQED 139 + CPVC+ + + +LRPNR L ++V +++ K LC H E L LFC ED Sbjct: 62 RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYED 121 Query: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199 + +C +C S HR H +++ QEY+EK Q+ L+ L+ + QE + + +K Sbjct: 122 QEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGE 181 Query: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259 K +E R +I EF +L LD +Q L +LE+EE+ L+ + E L + + L Sbjct: 182 LKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLA 241 Query: 260 ELISDLERRCQGSTMELLQDVSDVTERS 287 L +++E +C S E+L+DV E++ Sbjct: 242 HLAAEVEGKCLQSGFEMLKDVKSTLEKN 269 >gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] Length = 477 Score = 207 bits (528), Expect = 3e-53 Identities = 153/488 (31%), Positives = 241/488 (49%), Gaps = 51/488 (10%) Query: 356 ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMG-----GKSSC 410 A ++ +QEE TC ICL+ T+P+ CGH+ CRACI +S ++A G G C Sbjct: 3 AVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPC 62 Query: 411 PVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVIC 470 P C +L N+ L + E ++ +K+DLC H E L LFC++D+ IC Sbjct: 63 PECREMSPQRNLLPNRLLTKVAEMAQQ----HPGLQKQDLCQEHHEPLKLFCQKDQSPIC 118 Query: 471 WLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQV 530 +C S+EHR H + EE + + KL+ ++ L+++ L+A + W+ +V Sbjct: 119 VVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKV 178 Query: 531 QTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISD 590 + R+RI EF+++ L EEQR LQ LE EE++T + E+ L +Q + L+ Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238 Query: 591 VECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMV-SKKLKTVFHAPDLSRMLQMFRELTA 649 +E RS +++LQDM + ++ P++ + +TV P +L+ F E Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLE--- 295 Query: 650 VRCYWVDVTLNSVNLNLNLVL--SEDQRQVISVPIWP-------FQCYNYGVLGSQYFSS 700 DV ++ + L+L S +R + S P F Y V G FSS Sbjct: 296 ------DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSS 348 Query: 701 GKHYWEV--DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQN 758 G+HYWEV +++ W LGV SR K V +C P G+WV+ L Sbjct: 349 GRHYWEVGMNITGDALWALGVCRDNVSR--KDRVPKC-----------PENGFWVVQLSK 395 Query: 759 KCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 818 KY LS+ + + + PP +G+FLD+EAG VSF++V S GS ++ +S+ F Sbjct: 396 GTKY------LSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSV-SDGSHLHTYSQATF 448 Query: 819 SQPVYPYF 826 P+ P+F Sbjct: 449 PGPLQPFF 456 Score = 161 bits (408), Expect = 2e-39 Identities = 105/313 (33%), Positives = 157/313 (50%), Gaps = 17/313 (5%) Query: 37 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 90 ++EE TC ICL+ T+P+ CGH+FC+ACI + E G++G R CP C+ Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68 Query: 91 YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150 NL PNR L + ++ PG Q K LC +H E L+LFCQ+D IC +C S Sbjct: 69 SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124 Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210 +EHR H EE Q Y+ K +E ++ L+ + L A + W+ +++ R R Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184 Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270 I EF ++ L EQR L+ LE EE++ + E+ L Q SL L+ LE R Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244 Query: 271 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLR-----VCRELTDV 324 +++LQD+ + R +++ PE A PT+ R++ R P +LR V + T Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSA 304 Query: 325 QSYWAIQGSLTRR 337 Y + S RR Sbjct: 305 YPYLLLYESRQRR 317 >gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] Length = 477 Score = 207 bits (528), Expect = 3e-53 Identities = 153/488 (31%), Positives = 241/488 (49%), Gaps = 51/488 (10%) Query: 356 ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMG-----GKSSC 410 A ++ +QEE TC ICL+ T+P+ CGH+ CRACI +S ++A G G C Sbjct: 3 AVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPC 62 Query: 411 PVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVIC 470 P C +L N+ L + E ++ +K+DLC H E L LFC++D+ IC Sbjct: 63 PECREMSPQRNLLPNRLLTKVAEMAQQ----HPGLQKQDLCQEHHEPLKLFCQKDQSPIC 118 Query: 471 WLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQV 530 +C S+EHR H + EE + + KL+ ++ L+++ L+A + W+ +V Sbjct: 119 VVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKV 178 Query: 531 QTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISD 590 + R+RI EF+++ L EEQR LQ LE EE++T + E+ L +Q + L+ Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238 Query: 591 VECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMV-SKKLKTVFHAPDLSRMLQMFRELTA 649 +E RS +++LQDM + ++ P++ + +TV P +L+ F E Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLE--- 295 Query: 650 VRCYWVDVTLNSVNLNLNLVL--SEDQRQVISVPIWP-------FQCYNYGVLGSQYFSS 700 DV ++ + L+L S +R + S P F Y V G FSS Sbjct: 296 ------DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSS 348 Query: 701 GKHYWEV--DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQN 758 G+HYWEV +++ W LGV SR K V +C P G+WV+ L Sbjct: 349 GRHYWEVGMNITGDALWALGVCRDNVSR--KDRVPKC-----------PENGFWVVQLSK 395 Query: 759 KCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 818 KY LS+ + + + PP +G+FLD+EAG VSF++V S GS ++ +S+ F Sbjct: 396 GTKY------LSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSV-SDGSHLHTYSQATF 448 Query: 819 SQPVYPYF 826 P+ P+F Sbjct: 449 PGPLQPFF 456 Score = 161 bits (408), Expect = 2e-39 Identities = 105/313 (33%), Positives = 157/313 (50%), Gaps = 17/313 (5%) Query: 37 IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 90 ++EE TC ICL+ T+P+ CGH+FC+ACI + E G++G R CP C+ Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68 Query: 91 YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150 NL PNR L + ++ PG Q K LC +H E L+LFCQ+D IC +C S Sbjct: 69 SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124 Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210 +EHR H EE Q Y+ K +E ++ L+ + L A + W+ +++ R R Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184 Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270 I EF ++ L EQR L+ LE EE++ + E+ L Q SL L+ LE R Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244 Query: 271 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLR-----VCRELTDV 324 +++LQD+ + R +++ PE A PT+ R++ R P +LR V + T Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSA 304 Query: 325 QSYWAIQGSLTRR 337 Y + S RR Sbjct: 305 YPYLLLYESRQRR 317 >gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sapiens] Length = 474 Score = 193 bits (491), Expect = 5e-49 Identities = 154/505 (30%), Positives = 236/505 (46%), Gaps = 66/505 (13%) Query: 362 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 421 ++QEE+TCPICL+ +P+S++CGH+ CR C+ + GG CP C + Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60 Query: 422 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 481 L+ N LA + E+ + +L P LC H E L LFC++D++ +C +C SQEH+ Sbjct: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117 Query: 482 HHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEF 541 H +E F+ +EKL + L + ++ L+ + T WK +++++R RI TEF Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177 Query: 542 DQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTME 601 +L + L EE LQRL +EE++T K E +L Q +++LI +V +SQ T+E Sbjct: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237 Query: 602 LLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNS 661 LLQ+ ++ SEI + + + K+KTV P + ML+ F+ V V L Sbjct: 238 LLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIPLMKEMLKRFQ---------VAVNLAE 287 Query: 662 VNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY--------------------GVLGSQ 696 + LV S++ R V S WP +NY VLG Sbjct: 288 DTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKN 347 Query: 697 YFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVR-RCANRQNLYTKYRPLFGYWVIG 755 F+SGKHYWEV+ +GV CR M R + + ++ Y GYW + Sbjct: 348 VFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGITDRSKMSPDVGIWAIYWSAAGYWPL- 403 Query: 756 LQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSK 815 G +P + RVGV+LD G VSF++ G ++ FS Sbjct: 404 ------IGFPGTPTQQEPAL---------HRVGVYLDRGTGNVSFYSAVD-GVHLHTFS- 446 Query: 816 CCFSQPVYPYFNPWNCPAPMTLCPP 840 C + P+F W P + PP Sbjct: 447 CSSVSRLRPFF--WLSPLASLVIPP 469 Score = 171 bits (432), Expect = 3e-42 Identities = 97/282 (34%), Positives = 159/282 (56%), Gaps = 10/282 (3%) Query: 36 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95 DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60 Query: 96 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155 LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+ Sbjct: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117 Query: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215 H ++E + Y+EK +S + L + ++ L + T WK++++ +R RI TEF Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177 Query: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275 ++L N L E L++L +EE++ + + E L SL++LI ++ + Q T+E Sbjct: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237 Query: 276 LLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRAPDLKRMLR 316 LLQ+ +V RSE + EA+ K++++ + P +K ML+ Sbjct: 238 LLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQIPLMKEMLK 277 >gi|157743261 tripartite motif-containing 75 [Homo sapiens] Length = 468 Score = 192 bits (487), Expect = 1e-48 Identities = 140/495 (28%), Positives = 240/495 (48%), Gaps = 55/495 (11%) Query: 360 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 419 L +Q E C ICL+ L++P++++CGH+ CR+CI +++ + CPVC Sbjct: 7 LTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCI----QQSWLDLQELFPCPVCRHQCQE 62 Query: 420 EHLQANQHLANIVERLKEVKLSPDNGKKRD---LCDHHGEKLLLFCKEDRKVICWLCERS 476 H ++N L ++E K ++ + N +K++ LC+ H + L +FCKED V+C LC + Sbjct: 63 GHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQP 122 Query: 477 QEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQR 536 +H+GHH E+ +++ + ++ LKK+ + +KL + ++ + V+ +RQ Sbjct: 123 PDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE 182 Query: 537 IQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQ 596 + +EF+ L L+ E+Q L RL EEEK K + ++ +S V S+ Sbjct: 183 LSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSE 242 Query: 597 WSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKT--VFHAPDLSRMLQMFRELTAVRCYW 654 S +ELL S I + E P + S LK P S + ++ ++ + Sbjct: 243 LSELELL---SQIKIFYESENESSPSIFSIHLKRDGCSFPPQYSALQRIIKK------FK 293 Query: 655 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQ-CYNYGVLGSQYFSSGKHYWEV 707 V++ L+ + NL++SED+++V VP +P + VLG YF SG+H+WE+ Sbjct: 294 VEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEI 353 Query: 708 DVSKKTAWILGVYCR----TYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG 763 +V K+ W +G+ C+ T +R + C W I LQ+ G Sbjct: 354 EVGDKSEWAIGI-CKDSLPTKARRPSSAQQEC----------------WRIELQDD---G 393 Query: 764 VFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVY 823 P L + V +G+FLDYE G +SF+N+ + S I F+ F+ P+ Sbjct: 394 YHAPGAFPTP----LLLEVKARAIGIFLDYEMGEISFYNM-AEKSHICTFTD-TFTGPLR 447 Query: 824 PYFNPWNCPAPMTLC 838 PYF P+ +C Sbjct: 448 PYFYVGPDSQPLRIC 462 Score = 141 bits (356), Expect = 2e-33 Identities = 74/250 (29%), Positives = 134/250 (53%), Gaps = 7/250 (2%) Query: 34 LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93 L ++ E C ICL+ L++P++I+CGH+FC++CI ++S + + CPVC+ Q Sbjct: 7 LTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCI----QQSWLDLQELFPCPVCRHQCQE 62 Query: 94 GNLRPNRHLANIV---RRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150 G+ R N L ++ + L+ KQ + LC H + L +FC+ED V+C LC + Sbjct: 63 GHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQP 122 Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210 +H+GHH +E+ A Y+++F ++ LK + + +KL + +K + +E +R Sbjct: 123 PDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE 182 Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270 + +EF L LDR +Q L +L +EEK + + + + +L+ +S + + Sbjct: 183 LSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSE 242 Query: 271 GSTMELLQDV 280 S +ELL + Sbjct: 243 LSELELLSQI 252 >gi|31542779 tripartite motif family-like 1 [Homo sapiens] Length = 468 Score = 191 bits (486), Expect = 2e-48 Identities = 148/499 (29%), Positives = 248/499 (49%), Gaps = 53/499 (10%) Query: 359 ILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYS 418 ++ N++EE+TC ICL+ + P++ +CGHS C C+ S +E T + SCP C + Sbjct: 6 LMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPL----SCPECWRTLE 61 Query: 419 FEHLQANQ---HLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCER 475 H Q+N+ LA+I +L+ L ++ + K L ++ Sbjct: 62 GPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFV----- 116 Query: 476 SQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQ 535 +Q H + L+ E + +EKLQ +L L+ +EA+ + +E + + +T +Q Sbjct: 117 AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQ 176 Query: 536 RIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRS 595 + +E+ ++ L EEQ +LQ LE+EEK+ + K E +L QQ + + ++I+ +E S Sbjct: 177 VVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSS 236 Query: 596 QWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV 655 Q S E L+++ G ++ SE L+ P+ + +L ++ M +M R+ + Sbjct: 237 QSSAFESLEEVRGALERSEPLLLQCPEATTTELSLC----RITGMKEMLRKFS------T 286 Query: 656 DVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQC-YNYGVLGSQYFSSGKHYWEVD 708 ++TL+ N LVLSED + V +P P + + VLG+Q F+SG+HYWEV+ Sbjct: 287 EITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVE 346 Query: 709 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 768 V KT W +G+ + SR + NL LF +IGL+ Y ++ S Sbjct: 347 VGNKTEWEVGICKDSVSR-----------KGNLPKPPGDLFS--LIGLKIGDDYSLWVSS 393 Query: 769 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 828 V P C+VGVFLDYE+G ++F+N T SLIY F + F + + P F+P Sbjct: 394 PLKGQHV-----REPVCKVGVFLDYESGHIAFYNGTDE-SLIYSFPQASFQEALRPIFSP 447 Query: 829 -----WNCPAPMTLCPPSS 842 P+T+C +S Sbjct: 448 CLPNEGTNTDPLTICSLNS 466 Score = 127 bits (320), Expect = 3e-29 Identities = 86/290 (29%), Positives = 145/290 (50%), Gaps = 13/290 (4%) Query: 30 TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQT 89 T+ ++ ++REE+TC ICL+ + P++ +CGHSFC C+ + E SCP C Sbjct: 3 TADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEE----HNTPLSCPECWR 58 Query: 90 SYQPGNLRPNRHL---ANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWL 146 + + + + N L A+I R+LR VL + + K ++ G Sbjct: 59 TLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFV-- 116 Query: 147 CERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEP 206 +Q H + L E + ++EK QE L L+ +EA+ + +E+ + + + Sbjct: 117 ---AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKT 173 Query: 207 ERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266 + + +E+ ++ L EQ +L+ LEQEEK+ +R + E L Q +SL ++I+ +E Sbjct: 174 CKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIE 233 Query: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316 Q S E L++V ERSE L+ PEA T+L S+ R +K MLR Sbjct: 234 SSSQSSAFESLEEVRGALERSEPLLLQCPEATTTEL-SLCRITGMKEMLR 282 >gi|169202375 PREDICTED: tripartite motif-containing protein 64B-like [Homo sapiens] Length = 449 Score = 190 bits (483), Expect = 4e-48 Identities = 141/482 (29%), Positives = 235/482 (48%), Gaps = 48/482 (9%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 M S L Q E+ C IC+ +P+++DCGHS CR C+ + ++E M CP C Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPM----RCPSCR 56 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473 + + N L + ++ + P N D +C H E LFC+ D++++C C Sbjct: 57 KTSEKPNFNTNLVLKKLSSLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114 Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSW---KYQV 530 S EH H +EC+EKL +K + E ++ ++ +E +++ K V Sbjct: 115 SESPEHMAHSHSPIGWAAEECREKL---IKEMDYLWEINQETRNNLNQETSTFHSLKDYV 171 Query: 531 QTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISD 590 ++ I ++ ++ L+ EEQR LQ LE E ++ + +++ + Q + ++++ + Sbjct: 172 SVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRE 231 Query: 591 VECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAV 650 + + LLQD+ + +++ +++KP+ V+ +L T + + ML FR Sbjct: 232 LWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPEL-TSWCITGVLDMLNNFR----- 285 Query: 651 RCYWVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHY 704 VD L++ + + LSED R VI S P P ++ V G+Q F+SGKHY Sbjct: 286 ----VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHY 341 Query: 705 WEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 764 WEVDV+ + WILGV + + +V+ +++I + Y Sbjct: 342 WEVDVTLSSNWILGVCRDSRTADANFVIDSDER-------------FFLISSKRSNHY-- 386 Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824 SLS++ L + P RVGVFLDY+ G VSFF+V S GSLIY F FS P+ P Sbjct: 387 ---SLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRP 442 Query: 825 YF 826 +F Sbjct: 443 FF 444 Score = 115 bits (289), Expect = 1e-25 Identities = 71/279 (25%), Positives = 133/279 (47%), Gaps = 11/279 (3%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S L + E+ C IC+ +P++IDCGHSFC+ C+ E CP C+ Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG----RAPMRCPSCR 56 Query: 89 TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145 + + N N + L+++ R+ R + + C H E +LFC+ D +++C Sbjct: 57 KTSEKPNFNTNLVLKKLSSLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112 Query: 146 LCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQME 205 C S EH H + A+E +EK + + L QE S K+ + Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVS 172 Query: 206 PERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDL 265 + I ++ ++ LD EQR L+ LE+E ++ + +++++ + + ++++ +L Sbjct: 173 VRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYREL 232 Query: 266 ERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304 C + LLQDV +V+ R++ ++KP+ + +L S Sbjct: 233 WETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPELTS 271 >gi|210147600 tripartite motif-containing 64 [Homo sapiens] Length = 449 Score = 189 bits (480), Expect = 9e-48 Identities = 141/479 (29%), Positives = 228/479 (47%), Gaps = 42/479 (8%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 M S L Q E+ C IC+ +P+++DCGHS CR C+ + ++E M CP C Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPM----RCPSCR 56 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473 + N L + ++ + P N D +C H E LFC+ D++++C C Sbjct: 57 KISEKPNFNTNVVLKKLSSLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114 Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533 S EH H +EC+EKL + L + +E S K V Sbjct: 115 SESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVR 174 Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593 ++ I ++ ++ L+ EEQR LQ LE E ++ + +++ + Q + ++++ ++ Sbjct: 175 KRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWE 234 Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653 +ELLQD+ + +++ +++KP+ V+ +L T + + ML FR Sbjct: 235 TCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPEL-TSWCITGVLDMLNNFR-------- 285 Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707 VD L++ + + LSED R VI S P P ++ V G+Q F+SGKHYWEV Sbjct: 286 -VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEV 344 Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767 DV+ + WILGV + + +V+ +++I + Y Sbjct: 345 DVTLSSNWILGVCQDSRTADANFVIDSDER-------------FFLISSKRSNHY----- 386 Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826 SLS++ L + P +VGVFLDY+ G VSFF+V S GSLIY F FS P+ P+F Sbjct: 387 SLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 444 Score = 117 bits (293), Expect = 4e-26 Identities = 72/279 (25%), Positives = 133/279 (47%), Gaps = 11/279 (3%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S L + E+ C IC+ +P++IDCGHSFC+ C+ E CP C+ Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG----RAPMRCPSCR 56 Query: 89 TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145 + N N + L+++ R+ R + + C H E +LFC+ D +++C Sbjct: 57 KISEKPNFNTNVVLKKLSSLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112 Query: 146 LCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQME 205 C S EH H + A+E +EK + + L QE S K+ + Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVS 172 Query: 206 PERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDL 265 + I ++ ++ LD EQR L+ LE+E ++ + +++++ + + ++++ +L Sbjct: 173 VRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYREL 232 Query: 266 ERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304 C +ELLQDV +V+ R++ ++KP+ + +L S Sbjct: 233 WETCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPELTS 271 >gi|239755486 PREDICTED: tripartite motif-containing protein 64C-like isoform 2 [Homo sapiens] Length = 447 Score = 187 bits (476), Expect = 3e-47 Identities = 143/479 (29%), Positives = 232/479 (48%), Gaps = 44/479 (9%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 M S L Q E+ C IC+ +P++ DC HS CR C+ + ++E M CP+C Sbjct: 1 MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPM----RCPLCR 56 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473 + N L + ++ + P N D +C H E LFC+ D++++C C Sbjct: 57 KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114 Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533 S EH H +EC ++Q ++K + + ++ + ++ +E + + V+ + Sbjct: 115 SESPEHMAHSHSPIGWAAEEC--RVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVEDK 172 Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593 R RI + ++ L+ EEQR LQ LE E K+ + +++ + Q + ++++ ++ Sbjct: 173 RNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWE 232 Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653 +ELLQD+ I +++ ++ KP+ V+ +L T + + ML FR Sbjct: 233 TYHMPDVELLQDVGNISARTDLAQMPKPQPVNPEL-TSWCITGVLDMLNNFR-------- 283 Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707 VD L++ + LSED R+VI S P+ P ++ V +Q F+SGKHYWEV Sbjct: 284 -VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEV 342 Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767 DV+ + WILGV CR R A+ + + F I + Y Sbjct: 343 DVTHSSNWILGV-CRD---------SRTADTNIVIDSDKTFFS---ISSKTSNHY----- 384 Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826 SLS++ L + P VGVFLDY+ G VSFF+V S GSLIY F FS P+ P+F Sbjct: 385 SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 442 Score = 111 bits (278), Expect = 2e-24 Identities = 70/280 (25%), Positives = 136/280 (48%), Gaps = 15/280 (5%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S L + E+ C IC+ +P++ DC HSFC+ C+ E CP+C+ Sbjct: 1 MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56 Query: 89 TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145 + N N + LA++ R+ R + + C H E +LFC+ D +++C Sbjct: 57 KISEKPNFNTNVALKKLASLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112 Query: 146 LCERSQEHRGHHTFLVEEVAQEYQ-EKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQM 204 C S EH H + A+E + +K + + L QE + + ++ + + + + Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNN---LNQETSKFCSLV 169 Query: 205 EPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISD 264 E +R RI + ++ LD EQR L+ LE+E K+ + +++++ + + ++++ + Sbjct: 170 EDKRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRE 229 Query: 265 LERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304 L +ELLQDV +++ R++ + KP+ + +L S Sbjct: 230 LWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTS 269 >gi|239750044 PREDICTED: tripartite motif-containing protein 64C-like isoform 2 [Homo sapiens] Length = 447 Score = 187 bits (476), Expect = 3e-47 Identities = 143/479 (29%), Positives = 232/479 (48%), Gaps = 44/479 (9%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 M S L Q E+ C IC+ +P++ DC HS CR C+ + ++E M CP+C Sbjct: 1 MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPM----RCPLCR 56 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473 + N L + ++ + P N D +C H E LFC+ D++++C C Sbjct: 57 KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114 Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533 S EH H +EC ++Q ++K + + ++ + ++ +E + + V+ + Sbjct: 115 SESPEHMAHSHSPIGWAAEEC--RVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVEDK 172 Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593 R RI + ++ L+ EEQR LQ LE E K+ + +++ + Q + ++++ ++ Sbjct: 173 RNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWE 232 Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653 +ELLQD+ I +++ ++ KP+ V+ +L T + + ML FR Sbjct: 233 TYHMPDVELLQDVGNISARTDLAQMPKPQPVNPEL-TSWCITGVLDMLNNFR-------- 283 Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707 VD L++ + LSED R+VI S P+ P ++ V +Q F+SGKHYWEV Sbjct: 284 -VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEV 342 Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767 DV+ + WILGV CR R A+ + + F I + Y Sbjct: 343 DVTHSSNWILGV-CRD---------SRTADTNIVIDSDKTFFS---ISSKTSNHY----- 384 Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826 SLS++ L + P VGVFLDY+ G VSFF+V S GSLIY F FS P+ P+F Sbjct: 385 SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 442 Score = 111 bits (278), Expect = 2e-24 Identities = 70/280 (25%), Positives = 136/280 (48%), Gaps = 15/280 (5%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S L + E+ C IC+ +P++ DC HSFC+ C+ E CP+C+ Sbjct: 1 MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56 Query: 89 TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145 + N N + LA++ R+ R + + C H E +LFC+ D +++C Sbjct: 57 KISEKPNFNTNVALKKLASLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112 Query: 146 LCERSQEHRGHHTFLVEEVAQEYQ-EKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQM 204 C S EH H + A+E + +K + + L QE + + ++ + + + + Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNN---LNQETSKFCSLV 169 Query: 205 EPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISD 264 E +R RI + ++ LD EQR L+ LE+E K+ + +++++ + + ++++ + Sbjct: 170 EDKRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRE 229 Query: 265 LERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304 L +ELLQDV +++ R++ + KP+ + +L S Sbjct: 230 LWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTS 269 >gi|239744355 PREDICTED: tripartite motif-containing protein 64C-like isoform 1 [Homo sapiens] Length = 447 Score = 187 bits (476), Expect = 3e-47 Identities = 143/479 (29%), Positives = 232/479 (48%), Gaps = 44/479 (9%) Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414 M S L Q E+ C IC+ +P++ DC HS CR C+ + ++E M CP+C Sbjct: 1 MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPM----RCPLCR 56 Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473 + N L + ++ + P N D +C H E LFC+ D++++C C Sbjct: 57 KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114 Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533 S EH H +EC ++Q ++K + + ++ + ++ +E + + V+ + Sbjct: 115 SESPEHMAHSHSPIGWAAEEC--RVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVEDK 172 Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593 R RI + ++ L+ EEQR LQ LE E K+ + +++ + Q + ++++ ++ Sbjct: 173 RNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWE 232 Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653 +ELLQD+ I +++ ++ KP+ V+ +L T + + ML FR Sbjct: 233 TYHMPDVELLQDVGNISARTDLAQMPKPQPVNPEL-TSWCITGVLDMLNNFR-------- 283 Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707 VD L++ + LSED R+VI S P+ P ++ V +Q F+SGKHYWEV Sbjct: 284 -VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEV 342 Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767 DV+ + WILGV CR R A+ + + F I + Y Sbjct: 343 DVTHSSNWILGV-CRD---------SRTADTNIVIDSDKTFFS---ISSKTSNHY----- 384 Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826 SLS++ L + P VGVFLDY+ G VSFF+V S GSLIY F FS P+ P+F Sbjct: 385 SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 442 Score = 111 bits (278), Expect = 2e-24 Identities = 70/280 (25%), Positives = 136/280 (48%), Gaps = 15/280 (5%) Query: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88 M S L + E+ C IC+ +P++ DC HSFC+ C+ E CP+C+ Sbjct: 1 MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56 Query: 89 TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145 + N N + LA++ R+ R + + C H E +LFC+ D +++C Sbjct: 57 KISEKPNFNTNVALKKLASLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112 Query: 146 LCERSQEHRGHHTFLVEEVAQEYQ-EKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQM 204 C S EH H + A+E + +K + + L QE + + ++ + + + + Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNN---LNQETSKFCSLV 169 Query: 205 EPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISD 264 E +R RI + ++ LD EQR L+ LE+E K+ + +++++ + + ++++ + Sbjct: 170 EDKRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRE 229 Query: 265 LERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304 L +ELLQDV +++ R++ + KP+ + +L S Sbjct: 230 LWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTS 269 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,302,933 Number of Sequences: 37866 Number of extensions: 1568393 Number of successful extensions: 17205 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 412 Number of HSP's successfully gapped in prelim test: 886 Number of HSP's that attempted gapping in prelim test: 8794 Number of HSP's gapped (non-prelim): 6235 length of query: 842 length of database: 18,247,518 effective HSP length: 111 effective length of query: 731 effective length of database: 14,044,392 effective search space: 10266450552 effective search space used: 10266450552 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.