Guide to the Human Genome
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Search of human proteins with 51477690

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
         (842 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51477690 tripartite motif-containing 6 and tripartite motif-c...  1718   0.0  
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]     1010   0.0  
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]     1010   0.0  
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    665   0.0  
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            618   e-177
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    612   e-175
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   536   e-152
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]     524   e-148
gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]      518   e-146
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...   384   e-106
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...   383   e-106
gi|15208660 tripartite motif protein 21 [Homo sapiens]                371   e-102
gi|37622899 ring finger protein 137 [Homo sapiens]                    296   4e-80
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            271   2e-72
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             265   1e-70
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              256   5e-68
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   239   1e-62
gi|22749269 ring finger protein 129 [Homo sapiens]                    239   1e-62
gi|5730009 ret finger protein [Homo sapiens]                          235   1e-61
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   229   6e-60
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   207   3e-53
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    207   3e-53
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   193   5e-49
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            192   1e-48
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             191   2e-48
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...   190   4e-48
gi|210147600 tripartite motif-containing 64 [Homo sapiens]            189   9e-48
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...   187   3e-47
gi|239750044 PREDICTED: tripartite motif-containing protein 64C-...   187   3e-47
gi|239744355 PREDICTED: tripartite motif-containing protein 64C-...   187   3e-47

>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 1718 bits (4450), Expect = 0.0
 Identities = 842/842 (100%), Positives = 842/842 (100%)

Query: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60
           MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH
Sbjct: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60

Query: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120
           SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL
Sbjct: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120

Query: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180
           KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK
Sbjct: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180

Query: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240
           NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG
Sbjct: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240

Query: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300
           LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT
Sbjct: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300

Query: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKIL 360
           KLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKIL
Sbjct: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYWAIQGSLTRRERRASGVRTRRSQGSSAMASKIL 360

Query: 361 LNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFE 420
           LNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFE
Sbjct: 361 LNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFE 420

Query: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480
           HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR
Sbjct: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480

Query: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540
           GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE
Sbjct: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540

Query: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600
           FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM
Sbjct: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600

Query: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 660
           ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN
Sbjct: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 660

Query: 661 SVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVY 720
           SVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVY
Sbjct: 661 SVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGVY 720

Query: 721 CRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSM 780
           CRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSM
Sbjct: 721 CRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSM 780

Query: 781 AVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP 840
           AVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP
Sbjct: 781 AVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP 840

Query: 841 SS 842
           SS
Sbjct: 841 SS 842


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 1010 bits (2612), Expect = 0.0
 Identities = 488/488 (100%), Positives = 488/488 (100%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
           ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
           RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
           QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
           SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300

Query: 655 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 714
           VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 360

Query: 715 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 774
           WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE
Sbjct: 361 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 420

Query: 775 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 834
           VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP
Sbjct: 421 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 480

Query: 835 MTLCPPSS 842
           MTLCPPSS
Sbjct: 481 MTLCPPSS 488



 Score =  376 bits (966), Expect = e-104
 Identities = 188/300 (62%), Positives = 232/300 (77%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            Q STMELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 1010 bits (2612), Expect = 0.0
 Identities = 488/488 (100%), Positives = 488/488 (100%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
           ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
           RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
           QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
           SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300

Query: 655 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 714
           VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTA 360

Query: 715 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 774
           WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE
Sbjct: 361 WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPE 420

Query: 775 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 834
           VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP
Sbjct: 421 VLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAP 480

Query: 835 MTLCPPSS 842
           MTLCPPSS
Sbjct: 481 MTLCPPSS 488



 Score =  376 bits (966), Expect = e-104
 Identities = 188/300 (62%), Positives = 232/300 (77%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            Q STMELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  665 bits (1716), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60
           MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH
Sbjct: 1   MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGH 60

Query: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120
           SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL
Sbjct: 61  SFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQL 120

Query: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180
           KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK
Sbjct: 121 KAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLK 180

Query: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240
           NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG
Sbjct: 181 NEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKG 240

Query: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300
           LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT
Sbjct: 241 LRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPT 300

Query: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYW 328
           KLRSMFRAPDLKRMLRVCRELTDVQSYW
Sbjct: 301 KLRSMFRAPDLKRMLRVCRELTDVQSYW 328



 Score =  563 bits (1452), Expect = e-160
 Identities = 294/496 (59%), Positives = 361/496 (72%), Gaps = 12/496 (2%)

Query: 353 SAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPV 412
           + M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPV
Sbjct: 27  ATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPV 86

Query: 413 CGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWL 472
           C  SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWL
Sbjct: 87  CQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWL 146

Query: 473 CERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQT 532
           CERSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ 
Sbjct: 147 CERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEP 206

Query: 533 ERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVE 592
           ER RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E
Sbjct: 207 ERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266

Query: 593 CRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRC 652
            R Q STMELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ 
Sbjct: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQS 326

Query: 653 YWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWE 706
           YWVDVTLN    NLNLVL++++RQV      +S P    + Y+  VLGSQ+FSSGKHYWE
Sbjct: 327 YWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWE 386

Query: 707 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFE 766
           VDV+KKTAWILGV   +      +     A   + Y++Y+P  GYWVIGLQ+  +Y  +E
Sbjct: 387 VDVAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYE 444

Query: 767 ESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826
           +S  S    L LSM VPP RVGVFLDYEAG VSF+NVT+HG  IY FSK  F   + PYF
Sbjct: 445 DSSPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500

Query: 827 NPWNCPAPMTLCPPSS 842
           NP NC  PMTL  PSS
Sbjct: 501 NPCNCVIPMTLRRPSS 516


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  618 bits (1594), Expect = e-177
 Identities = 303/498 (60%), Positives = 376/498 (75%), Gaps = 10/498 (2%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           M   + +++++EVTCPICLELLTEPLSLDCGHS C+ACIT   KE+V    G+SSCPVC 
Sbjct: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
             +   +L+ N+HLANIVER+KEVK+SP  G+KRD+C+HHG+KL +FCKED KVICW+CE
Sbjct: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
            SQEH+GH T    EV KECQEKLQ  L+RL KE++EAEKLE DIR+E+T+WK  +Q ER
Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
           Q+I   F+++R IL+NEEQRELQ+LEE E   LD  A A D+LVQQ+Q    LISD++ R
Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240

Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
            + S++E+LQD+  +MK SE W LKKPK VSKKLK+VF  PDLS MLQ+ +ELT V+ YW
Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300

Query: 655 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN------YGVLGSQYFSSGKHYWEVD 708
           VDV LN  +   N+ +S DQRQV +V    F+  N      +GV G QYFSSGK+YWEVD
Sbjct: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD 360

Query: 709 VSKKTAWILGVYCRTYSRHMK----YVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 764
           VS K AWILGV+ +  S + +    +      N   +Y++YRP +GYWVIGLQN C+Y  
Sbjct: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420

Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824
           FE+S SSDP+VLTL MAVPPCR+GVFLDYEAGIVSFFNVT+HG+LIYKFS C FS+P YP
Sbjct: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480

Query: 825 YFNPWNCPAPMTLCPPSS 842
           YFNPWNC  PMT+CPPSS
Sbjct: 481 YFNPWNCLVPMTVCPPSS 498



 Score =  369 bits (946), Expect = e-102
 Identities = 181/300 (60%), Positives = 228/300 (76%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M   V VDI +EVTCPICLELLTEPLS+DCGHSFCQACIT   +ESVI   GE SCPVCQ
Sbjct: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
           T +QPGNLRPNRHLANIV R++EV + P +  K  +C  HG+KLQ+FC+EDGKVICW+CE
Sbjct: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
            SQEH+GH TF + EV +E QEK Q +L++L  E+QEAEKL   IR+++T+WKN ++ ER
Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            +I   FN++R ILD  EQREL+KLE+ E   L  +  A + LV Q Q    LISDL+RR
Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            +GS++E+LQDV DV +RSE WTL+KP+++  KL+S+FR PDL  ML+V +ELTDVQ YW
Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  612 bits (1579), Expect = e-175
 Identities = 300/300 (100%), Positives = 300/300 (100%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ
Sbjct: 1   MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
           TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE
Sbjct: 61  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER
Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
           CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR
Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
           CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW
Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300



 Score =  563 bits (1451), Expect = e-160
 Identities = 294/494 (59%), Positives = 360/494 (72%), Gaps = 12/494 (2%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPVC 
Sbjct: 1   MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
            SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWLCE
Sbjct: 61  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
           RSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
            RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E R
Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240

Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
            Q STMELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ YW
Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300

Query: 655 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYGVLGSQYFSSGKHYWEVD 708
           VDVTLN    NLNLVL++++RQV      +S P    + Y+  VLGSQ+FSSGKHYWEVD
Sbjct: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVD 360

Query: 709 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 768
           V+KKTAWILGV   +      +     A   + Y++Y+P  GYWVIGLQ+  +Y  +E+S
Sbjct: 361 VAKKTAWILGVCSNSLGPTFSF--NHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDS 418

Query: 769 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 828
             S    L LSM VPP RVGVFLDYEAG VSF+NVT+HG  IY FSK  F   + PYFNP
Sbjct: 419 SPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474

Query: 829 WNCPAPMTLCPPSS 842
            NC  PMTL  PSS
Sbjct: 475 CNCVIPMTLRRPSS 488


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  536 bits (1382), Expect = e-152
 Identities = 285/504 (56%), Positives = 359/504 (71%), Gaps = 27/504 (5%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++   G +SSCPVC 
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
           ISY  E+++ N+H+AN+VE+L+EVKLSP+ G+K D C  HGEKLLLFC+ED KVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANLVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
           RSQEHRGHHT  TEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++
Sbjct: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
             +  +F+QLR IL+ EE  ELQ LE+EE+  L     +E E+VQQ Q +RELISD+E R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
            Q S MELLQ + G++K +E   LKKP+   K  + VF APDL  ML++FRELT VR YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298

Query: 655 VDVTLNSVNLNLNLVLSEDQRQVIS-----------VPIWPFQCYNY--GVLGSQYFSSG 701
           VDVT+   N++   V+SED+RQV S                F  +NY  G+LGSQ  +SG
Sbjct: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357

Query: 702 KHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 761
           KHYWEVDVSKKTAWILGV C  +       + +  N       Y+P +GYWVIGL+   K
Sbjct: 358 KHYWEVDVSKKTAWILGV-CAGFQPDAMCNIEKNEN-------YQPKYGYWVIGLEEGVK 409

Query: 762 YGVFEES---LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 818
              F++S     S P ++ LS+ + P RVGVFLDYEA  VSFFN+T+HG LIYKFS C F
Sbjct: 410 CSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSF 469

Query: 819 SQPVYPYFNPWNCPAPMTLCPPSS 842
           SQPV+PY NP  C  PMTLC PSS
Sbjct: 470 SQPVFPYLNPRKCGVPMTLCSPSS 493



 Score =  380 bits (975), Expect = e-105
 Identities = 188/300 (62%), Positives = 232/300 (77%), Gaps = 2/300 (0%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++  +GE SCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SYQP N+RPNRH+AN+V +LREV L P  Q K   CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANLVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTF  EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
             +  +F QLR+ILD  E  EL+ LE+EE+  L+ +  +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            QGS MELLQ V  V +R+E  TL+KPE  P   R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score =  524 bits (1349), Expect = e-148
 Identities = 259/262 (98%), Positives = 260/262 (99%), Gaps = 1/262 (0%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
           ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
           RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
           QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 595 SQWSTMELLQDMSGIMKWSEIW 616
           SQWSTMELLQDMSGIMKW  +W
Sbjct: 241 SQWSTMELLQDMSGIMKWC-VW 261



 Score =  328 bits (840), Expect = 2e-89
 Identities = 165/255 (64%), Positives = 199/255 (78%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +L++++EEVTCPICLELLTEPLS+DCGHS C+ACIT + +E+V    G+ SCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SY   +L+ N+HLANIV RL+EV L P    K  LC  HGEKL LFC+ED KVICWLCE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHT L EEV +E QEK Q  LK+LK EE+EAEKL A IRE+KTSWK Q++ ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
            RIQTEF+QLR+IL+  EQREL++LE+EEKK L    EAE++LV Q Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 269 CQGSTMELLQDVSDV 283
            Q STMELLQD+S +
Sbjct: 241 SQWSTMELLQDMSGI 255


>gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]
          Length = 243

 Score =  518 bits (1333), Expect = e-146
 Identities = 243/243 (100%), Positives = 243/243 (100%)

Query: 600 MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 659
           MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL
Sbjct: 1   MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 60

Query: 660 NSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV 719
           NSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV
Sbjct: 61  NSVNLNLNLVLSEDQRQVISVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV 120

Query: 720 YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLS 779
           YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLS
Sbjct: 121 YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLS 180

Query: 780 MAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP 839
           MAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP
Sbjct: 181 MAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCP 240

Query: 840 PSS 842
           PSS
Sbjct: 241 PSS 243



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 30/55 (54%), Positives = 42/55 (76%)

Query: 274 MELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
           MELLQD+S + + SE W L+KP+ +  KL+++F APDL RML++ RELT V+ YW
Sbjct: 1   MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 55


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
           sapiens]
          Length = 347

 Score =  384 bits (985), Expect = e-106
 Identities = 191/305 (62%), Positives = 235/305 (77%), Gaps = 2/305 (0%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++  +GE SCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SYQP N+RPNRH+ANIV +LREV L P  Q K   CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
             +  +F QLR+ILD  E  EL+ LE+EE+  L+ +  +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            QGS MELLQ V  V +R+E  TL+KPE  P   R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298

Query: 329 AIQGS 333
             + S
Sbjct: 299 GKEKS 303



 Score =  366 bits (940), Expect = e-101
 Identities = 184/300 (61%), Positives = 234/300 (78%), Gaps = 2/300 (0%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++   G +SSCPVC 
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
           ISY  E+++ N+H+ANIVE+L+EVKLSP+ G+K D C  HGEKLLLFC+ED KVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
           RSQEHRGHHT LTEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
             +  +F+QLR IL+ EE  ELQ LE+EE+  L     +E E+VQQ Q +RELISD+E R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
            Q S MELLQ + G++K +E   LKKP+   K  + VF APDL  ML++FRELT VR YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
           sapiens]
          Length = 326

 Score =  383 bits (984), Expect = e-106
 Identities = 190/300 (63%), Positives = 233/300 (77%), Gaps = 2/300 (0%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++  +GE SCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
            SYQP N+RPNRH+ANIV +LREV L P  Q K   CA HGEKL LFCQEDGKVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
           RSQEHRGHHTFL EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
             +  +F QLR+ILD  E  EL+ LE+EE+  L+ +  +E ++V QTQSLRELISDLE R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
            QGS MELLQ V  V +R+E  TL+KPE  P   R +FRAPDLK ML V RELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298



 Score =  366 bits (940), Expect = e-101
 Identities = 184/300 (61%), Positives = 234/300 (78%), Gaps = 2/300 (0%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++   G +SSCPVC 
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
           ISY  E+++ N+H+ANIVE+L+EVKLSP+ G+K D C  HGEKLLLFC+ED KVICWLCE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
           RSQEHRGHHT LTEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
             +  +F+QLR IL+ EE  ELQ LE+EE+  L     +E E+VQQ Q +RELISD+E R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
            Q S MELLQ + G++K +E   LKKP+   K  + VF APDL  ML++FRELT VR YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  371 bits (953), Expect = e-102
 Identities = 213/500 (42%), Positives = 301/500 (60%), Gaps = 51/500 (10%)

Query: 355 MASKILLNVQ-EEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVC 413
           MAS   L +  EEVTCPICL+   EP+S++CGHS C+ CI+   K      GG S CPVC
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGK------GGGSVCPVC 54

Query: 414 GISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLC 473
              +  ++L+ N+ LAN+V  LKE+      G + + C  HGE+L LFC++D K +CW+C
Sbjct: 55  RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVC 114

Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533
            +S++HR H  V  EE  +E QEKLQ  L  L++++E AEKLE +I  ++  WK  V+T+
Sbjct: 115 AQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ 174

Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593
           + RI  EF Q ++ L  EEQR+LQ LE++E++ L    E E +L QQ Q ++ELIS+++ 
Sbjct: 175 KSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDR 234

Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653
           R   S +ELLQ++  +++ SE W LK   + S +L++V H P L +ML         R  
Sbjct: 235 RCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML---------RTC 285

Query: 654 WVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG-VLGSQYFSSGKHYWE 706
            V +TL+    N  L+LSED+RQV       S+P    +  +Y  VLG+Q+F SGKHYWE
Sbjct: 286 AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWE 345

Query: 707 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKY--GV 764
           VDV+ K AW LGV CR   R   + +    +            G+W I L NK KY  G 
Sbjct: 346 VDVTGKEAWDLGV-CRDSVRRKGHFLLSSKS------------GFWTIWLWNKQKYEAGT 392

Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824
           + ++         L + VPPC+VG+FLDYEAG+VSF+N+T HGSLIY FS+C F+ P+ P
Sbjct: 393 YPQT--------PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRP 444

Query: 825 YFNP-----WNCPAPMTLCP 839
           +F+P         AP+TLCP
Sbjct: 445 FFSPGFNDGGKNTAPLTLCP 464



 Score =  272 bits (695), Expect = 1e-72
 Identities = 135/280 (48%), Positives = 187/280 (66%), Gaps = 6/280 (2%)

Query: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRP 98
           EEVTCPICL+   EP+SI+CGHSFCQ CI      S +G+ G   CPVC+  +   NLRP
Sbjct: 12  EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65

Query: 99  NRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHT 158
           NR LAN+V  L+E+     +  +   CA HGE+L LFC++DGK +CW+C +S++HR H  
Sbjct: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125

Query: 159 FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQL 218
             +EE AQEYQEK Q +L +L+ +++ AEKL   I  K+  WK  +E ++ RI  EF Q 
Sbjct: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185

Query: 219 RNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQ 278
           +N L   EQR+L++LE++E++ LRI+ E E  L  Q+Q+L+ELIS+L+RRC  S +ELLQ
Sbjct: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245

Query: 279 DVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVC 318
           +V  V ERSE W L+  +    +LRS+   P LK+MLR C
Sbjct: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTC 285


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  296 bits (759), Expect = 4e-80
 Identities = 179/498 (35%), Positives = 270/498 (54%), Gaps = 50/498 (10%)

Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422
           + EEV CPIC+  L EP+S+DCGHS C +C++   +    S     +CP+C       +L
Sbjct: 10  IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNL 69

Query: 423 QANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH 482
           + N  LAN+VE+++ ++L P  G K DLC+ HGEKL +FCKED  ++C  C +S EH  H
Sbjct: 70  RPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAH 129

Query: 483 HTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFD 542
             V  E+V  E + +L   L+ LKKE+EEA KLE   R+   +WK QV+T +Q I  EF+
Sbjct: 130 SVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFE 189

Query: 543 QLRSILNN----------EEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVE 592
           + + +L            E    L  L+ E  +T+ K      EL+QQ Q++  +I++++
Sbjct: 190 KYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249

Query: 593 CRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRC 652
            RSQ     +LQD+  ++  S+ W L++P+ +S +LKT      L  +L         + 
Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREIL---------KT 300

Query: 653 YWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG-VLGSQYFSSGKHYW 705
           Y  DV L+       L++SED+++V        +P  P + Y Y  VLGSQ  SSG+HYW
Sbjct: 301 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYW 360

Query: 706 EVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVF 765
           EV+V  ++ W LGV  +   R           ++ +Y    P +G+WVI L+   +Y   
Sbjct: 361 EVEVGDRSEWGLGVCKQNVDR-----------KEVVYLS--PHYGFWVIRLRKGNEY--- 404

Query: 766 EESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPY 825
               +   E   LS+ VPP RVG+F+DYEA  +SF+NVT  GS I+ F +  F   + PY
Sbjct: 405 ---RAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPY 461

Query: 826 FNP-----WNCPAPMTLC 838
           F+P      N  AP+ +C
Sbjct: 462 FSPCYSIGTNNTAPLAIC 479



 Score =  210 bits (534), Expect = 5e-54
 Identities = 108/290 (37%), Positives = 173/290 (59%), Gaps = 10/290 (3%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96
           I EEV CPIC+  L EP+SIDCGHSFC +C++         Q    +CP+C+   QP NL
Sbjct: 10  IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNL 69

Query: 97  RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 156
           RPN  LAN+V ++R + L PG  LK  LC  HGEKL++FC+ED  ++C  C +S EH  H
Sbjct: 70  RPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAH 129

Query: 157 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 216
               +E+VA EY+ +  E+L+ LK E++EA KL    R++  +WK Q+E  +  I  EF 
Sbjct: 130 SVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFE 189

Query: 217 QLRNILDRVE----------QRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266
           + + +L++ +             L  L++E  + ++ +E   ++L+ Q+Q L  +I++L+
Sbjct: 190 KYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249

Query: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316
            R Q     +LQD+ +V  RS+ W+L++PE +  +L++  R   L+ +L+
Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILK 299


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  271 bits (693), Expect = 2e-72
 Identities = 169/487 (34%), Positives = 259/487 (53%), Gaps = 41/487 (8%)

Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422
           ++E+  CP+CL+ L EP+S+DCGHS C  CI+   +++  + GG  +CP C   +     
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69

Query: 423 QANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH 482
           + N+ LA +VE ++ + L    G +R  C  HGE L  FC+ED   +CW+C+   EHR H
Sbjct: 70  RPNRQLAGLVESVRRLGLGAGPGARR--CARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127

Query: 483 HTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFD 542
            T   +E     Q KLQ  L+ ++KE E+A   EA++ ++   WK +V+ +RQR + EF+
Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187

Query: 543 QLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTMEL 602
           + R  L  EEQR+L+RLE EE+ TL +  E++  LVQQ + ++EL  +++ R Q   + L
Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247

Query: 603 LQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNSV 662
           L+ + G++  S+     + + +  +LKT    P    +L+ F+         VDV L+  
Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQ---------VDVKLDPA 298

Query: 663 NLNLNLVLSEDQRQVISVPIW---PFQCYNYG----VLGSQYFSSGKHYWEVDVSKKTAW 715
             + +L+L+ D R V     W   P     +     +LG Q FSSG+HYWEV V +   W
Sbjct: 299 TAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEW 358

Query: 716 ILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEV 775
            LGV   T  R  +             T   P  G W + L    +Y V      + P V
Sbjct: 359 GLGVCQDTLPRKGE-------------TTPSPENGVWALWLLKGNEYMVL-----ASPSV 400

Query: 776 LTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPM 835
             L +  P C +G+FLDYEAG +SF+NVT  GS IY F++  FS  + PYF  + C A  
Sbjct: 401 PLLQLESPRC-IGIFLDYEAGEISFYNVTD-GSYIYTFNQ-LFSGLLRPYF--FICDATP 455

Query: 836 TLCPPSS 842
            + PP++
Sbjct: 456 LILPPTT 462



 Score =  217 bits (553), Expect = 3e-56
 Identities = 108/280 (38%), Positives = 169/280 (60%), Gaps = 2/280 (0%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96
           +RE+  CP+CL+ L EP+S+DCGHSFC  CI+    +S   Q G  +CP C+  ++P   
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69

Query: 97  RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 156
           RPNR LA +V  +R + LG G   +   CA HGE L  FC+ED   +CW+C+   EHR H
Sbjct: 70  RPNRQLAGLVESVRRLGLGAGPGARR--CARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127

Query: 157 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 216
            T  ++E A  YQ K Q +L+ ++ E ++A    A + +K   WK ++E +R R + EF 
Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187

Query: 217 QLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMEL 276
           + R  L + EQR+L++LE EE+  L+ + E+++ LV Q+++L+EL  +L+ RCQ   + L
Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247

Query: 277 LQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316
           L+ V  V  RS+  T  + E +P +L++    P  + +LR
Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLR 287


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  265 bits (677), Expect = 1e-70
 Identities = 170/494 (34%), Positives = 262/494 (53%), Gaps = 48/494 (9%)

Query: 356 ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGI 415
           A  +  N+QEE TC ICL+  T+P+  DCGH+ CR CI    +       G  +CP C  
Sbjct: 3   APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPECRE 58

Query: 416 SYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCER 475
                +L+ N+ LA + E  +  +L P +   + +C  H E L  FC ++ +++C  CER
Sbjct: 59  LSPQRNLRPNRPLAKMAEMAR--RLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACER 116

Query: 476 SQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQ 535
           S EH  H     ++  ++ + KL+  L+ L+K+ ++A   +A   E    W+  V+++RQ
Sbjct: 117 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ 176

Query: 536 RIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRS 595
            +  EF++LR +L  EEQ+ LQRLEEEE + L +  E    L QQ   + ELI+++E R 
Sbjct: 177 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC 236

Query: 596 QWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV 655
           Q   + LLQD+   ++  +  +L+ P++V  +L+TV   P L   L+ FR          
Sbjct: 237 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG--------- 287

Query: 656 DVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG--VLGSQYFSSGKHYWEV 707
           DVTL+    N  L+LSED+R V       ++P  P + ++ G  VLG + F+SG+HYWEV
Sbjct: 288 DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSP-ERFDPGPCVLGQERFTSGRHYWEV 346

Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767
           +V  +T+W LGV CR      +       N            G+W++         VF  
Sbjct: 347 EVGDRTSWALGV-CRENVNRKEKGELSAGN------------GFWIL---------VFLG 384

Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFN 827
           S  +  E     +  PP RVG+FLDYEAG +SF++ T  GSL++ F +  FS  + P F+
Sbjct: 385 SYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFS 443

Query: 828 PW-NCPAPMTLCPP 840
           P  + P PMT+C P
Sbjct: 444 PLSSSPTPMTICRP 457



 Score =  183 bits (465), Expect = 5e-46
 Identities = 105/289 (36%), Positives = 159/289 (55%), Gaps = 7/289 (2%)

Query: 29  MTSPVL-VDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVC 87
           M +P L  +++EE TC ICL+  T+P+  DCGH+FC+ CI    R      EG  +CP C
Sbjct: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPEC 56

Query: 88  QTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLC 147
           +      NLRPNR LA +    R   L P   +   +C  H E L  FC ++ +++C  C
Sbjct: 57  RELSPQRNLRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114

Query: 148 ERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE 207
           ERS EH  H    +++ A++ + K ++SL+ L+ + Q+A    A   E    W+  +E +
Sbjct: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ 174

Query: 208 RCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLER 267
           R  +  EF +LR +L   EQ+ L++LE+EE + L  + E    L  Q+  L ELI++LE 
Sbjct: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234

Query: 268 RCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316
           RCQ   + LLQD+ D   R +   L+ PE +P +LR++ R P L   LR
Sbjct: 235 RCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLR 283


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  256 bits (655), Expect = 5e-68
 Identities = 166/491 (33%), Positives = 256/491 (52%), Gaps = 50/491 (10%)

Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSS--CPVCGISYSFE 420
           + EE TC ICL L+T P+S++CGHS C  CIT   K        + +  CP C   +  +
Sbjct: 10  MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69

Query: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480
            L+ N+ L +++E LKE             C+ HGE+  LFC+++ ++ICW CER+ +H+
Sbjct: 70  SLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICWRCERAPQHK 122

Query: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540
           GH T L E+V +  +EKLQ  + +LK+ E+   + +       T WK +VQ +RQ+I+++
Sbjct: 123 GHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSD 182

Query: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600
           F  L+  L+ EE+  L RLE+EE++TL +  + E  L  +   ++  I ++E + Q S  
Sbjct: 183 FKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQ 242

Query: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 660
           +LLQ+++  +  S   +L+  + VS +L T+ +   L      F     +R + V VTL+
Sbjct: 243 KLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKL-----YFDVKKMLRSHQVSVTLD 297

Query: 661 SVNLNLNLVLSEDQRQVI-----------SVPIWPFQCYNYGVLGSQYFSSGKHYWEVDV 709
               +  L+LSED+RQV            S     F C    VLG + F+SG+ Y+EVDV
Sbjct: 298 PDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC----VLGCEGFTSGRRYFEVDV 353

Query: 710 SKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESL 769
            + T W LGV      R                 K  P  G+W + L  K  Y     +L
Sbjct: 354 GEGTGWDLGVCMENVQR-------------GTGMKQEPQSGFWTLRLCKKKGY----VAL 396

Query: 770 SSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW 829
           +S P   +L +   P  VG+FLDYEAG+VSF+N  + G  I+ F K  FS  + PYF  +
Sbjct: 397 TSPP--TSLHLHEQPLLVGIFLDYEAGVVSFYNGNT-GCHIFTFPKASFSDTLRPYFQVY 453

Query: 830 NCPAPMTLCPP 840
              +P+ L PP
Sbjct: 454 QY-SPLFLPPP 463



 Score =  199 bits (507), Expect = 7e-51
 Identities = 106/285 (37%), Positives = 168/285 (58%), Gaps = 15/285 (5%)

Query: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITP---NGRESVIGQEGERSCPVCQTSYQPGN 95
           EE TC ICL L+T P+SI+CGHS+C  CIT    N  +  + QE    CP C+  +   +
Sbjct: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCCPQCRAPFHMDS 70

Query: 96  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
           LRPN+ L +++  L+E         + + C +HGE+  LFC+++G++ICW CER+ +H+G
Sbjct: 71  LRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKG 123

Query: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215
           H T LVE+V Q Y+EK Q+++ KLK  E    +       + T WK +++ +R +I+++F
Sbjct: 124 HTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183

Query: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275
             L+  L   E+  L +LE+EE++ L  + + E  L  ++  L+  I +LE +CQGS  +
Sbjct: 184 KNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQK 243

Query: 276 LLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLR 316
           LLQ+V+D   RS    L   EA+  +L +M        D+K+MLR
Sbjct: 244 LLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR 288


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  239 bits (609), Expect = 1e-62
 Identities = 163/503 (32%), Positives = 264/503 (52%), Gaps = 42/503 (8%)

Query: 352 SSAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCP 411
           S+A  +  L N+Q E +C +CLE L EP+ ++CGH+ C+ACIT   ++          CP
Sbjct: 12  SAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDF----PCP 67

Query: 412 VCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICW 471
           VC  +  +  L+ N+ L ++VE  K+++      +   LC  H E L LFC ED++ +C 
Sbjct: 68  VCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCL 127

Query: 472 LCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQ 531
           +C  S  HR H  V  ++  +E +EKLQ  L+ L+++ +E  + ++   ++    K  V+
Sbjct: 128 ICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVE 187

Query: 532 TERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDV 591
           + RQ+I  EF++L   L+ E+Q  L RLEEEE+  L +  E    L  +++ +  L ++V
Sbjct: 188 SRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEV 247

Query: 592 ECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVR 651
           E +   S  E+L+D+   ++  E  ++K  ++ S  ++   +  +  R     R++  ++
Sbjct: 248 EGKCLQSGFEMLKDVKSTLEKCE--KVKTMEVTSVSIELEKNFSNFPRQYFALRKI--LK 303

Query: 652 CYWVDVTLNSVNLNLNLVLSEDQRQVISV-------PIWPFQCYNYG-VLGSQYFSSGKH 703
               DVTL+    + NLVLSED++ V  V       P  P +   Y  VL ++ F+SG+H
Sbjct: 304 QLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRH 363

Query: 704 YWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG 763
           YWEV+V  KT W +G            V R   +R+   T   P  GYW + L N  KY 
Sbjct: 364 YWEVEVGDKTHWAVG------------VCRDSVSRKGELTPL-PETGYWRVRLWNGDKYA 410

Query: 764 VFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVY 823
                 ++      L + V P RVG+FLDYEAG +SF+NVT   S IY F+   F++ ++
Sbjct: 411 ------ATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDR-SHIYTFTD-TFTEKLW 462

Query: 824 PYFNPW-----NCPAPMTLCPPS 841
           P F P         AP+T+ PP+
Sbjct: 463 PLFYPGIRAGRKNAAPLTIRPPT 485



 Score =  163 bits (413), Expect = 5e-40
 Identities = 93/269 (34%), Positives = 147/269 (54%), Gaps = 6/269 (2%)

Query: 20  QAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE 79
           +AGA   A  T+  L +++ E +C +CLE L EP+ I+CGH+FC+ACIT    +     E
Sbjct: 8   EAGAS--AASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----E 61

Query: 80  GERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQED 139
            +  CPVC+ + +  +LRPNR L ++V   +++     K     LC  H E L LFC ED
Sbjct: 62  RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYED 121

Query: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199
            + +C +C  S  HR H    +++  QEY+EK Q+ L+ L+ + QE  +  +   +K   
Sbjct: 122 QEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGE 181

Query: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259
            K  +E  R +I  EF +L   LD  +Q  L +LE+EE+  L+ + E    L  + + L 
Sbjct: 182 LKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLA 241

Query: 260 ELISDLERRCQGSTMELLQDVSDVTERSE 288
            L +++E +C  S  E+L+DV    E+ E
Sbjct: 242 HLAAEVEGKCLQSGFEMLKDVKSTLEKCE 270


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  239 bits (609), Expect = 1e-62
 Identities = 158/497 (31%), Positives = 259/497 (52%), Gaps = 51/497 (10%)

Query: 360 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 419
           L+N+QEE +CPICLE L +P++++CGH+ CR+C++VS K+    +     CPVC   + +
Sbjct: 7   LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKD----LDDTFPCPVCRFCFPY 62

Query: 420 EHLQANQHLANIVERLKEVKLSPDNGKKRD---LCDHHGEKLLLFCKEDRKVICWLCERS 476
           +  + N  L N+ E  K++++     K++    +C+ H + L LFC +D +++C  C  S
Sbjct: 63  KSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFS 122

Query: 477 QEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQR 536
            +H+ H+    ++     +E L+  L+ L+   E  EK+      +    K +V+ +R+ 
Sbjct: 123 TKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREE 182

Query: 537 IQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQ 596
           I +EF+Q+R  L NE++  L+++++EE   L K  E   EL      ++ L+ +VE +S 
Sbjct: 183 INSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSV 242

Query: 597 WSTMELLQDMSGIMKWSEIWRLKKPKMVSKKL-KTVFHAP----DLSRMLQMFRELTAVR 651
            S +ELL     +    +   LK P++ S +L K  F  P     L R+++ F+      
Sbjct: 243 QSNLELLTQAKSM--HHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPFQ------ 294

Query: 652 CYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN-------YGVLGSQYFSSGKHY 704
              VDV L+    +  L++SED++ V         CY+         VLGSQ FSSG+HY
Sbjct: 295 ---VDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHY 351

Query: 705 WEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 764
           WEV+V  K  WILG            V + C  R N   +   L G+W IG   K  Y  
Sbjct: 352 WEVEVGNKPKWILG------------VCQDCLLR-NWQDQPSVLGGFWAIGRYMKSGY-- 396

Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824
               ++S P+   L   V P ++G+FLDYE G +SF+N+    S++Y F+  CF++ V+P
Sbjct: 397 ----VASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDR-SILYTFND-CFTEAVWP 450

Query: 825 YFNPWNCPAPMTLCPPS 841
           YF       P+ +C  S
Sbjct: 451 YFYTGTDSEPLKICSVS 467



 Score =  137 bits (346), Expect = 3e-32
 Identities = 76/272 (27%), Positives = 146/272 (53%), Gaps = 9/272 (3%)

Query: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93
           LV+++EE +CPICLE L +P++I+CGH+FC++C++ + ++     +    CPVC+  +  
Sbjct: 7   LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDL----DDTFPCPVCRFCFPY 62

Query: 94  GNLRPNRHLANIVRRLREVVLGPGK---QLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
            + R N  L N+    +++ +   K   Q +  +C  H + L LFC +D +++C  C  S
Sbjct: 63  KSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFS 122

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
            +H+ H+   +++ A  ++E  + SL+ L+N  +  EK+      K    K ++E +R  
Sbjct: 123 TKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREE 182

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           I +EF Q+R  L   ++  L++++ EE   L  + E   +L     +L+ L+ ++E +  
Sbjct: 183 INSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSV 242

Query: 271 GSTMELLQDVSDVTERSEFWTLRKPEALPTKL 302
            S +ELL     +    ++  L+ PE    +L
Sbjct: 243 QSNLELLTQAKSM--HHKYQNLKCPELFSFRL 272


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  235 bits (600), Expect = 1e-61
 Identities = 164/512 (32%), Positives = 253/512 (49%), Gaps = 61/512 (11%)

Query: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422
           +Q+E TCP+CL+   EP+ LDCGH++C AC+      A T++    SCP C  ++   H+
Sbjct: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNV----SCPQCRETFPQRHM 65

Query: 423 QANQHLANIVERLKEVKLSPDNGKKRDL--CDHHGEKLLLFCKEDRKVICWLCERSQEHR 480
           + N+HLAN+ + +K+++    +G   ++  C+ H E L L+C+ED+  IC +C+RS+EHR
Sbjct: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHR 125

Query: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540
           GH  +  EE  +  +E++Q  L  LK+ ++  ++  A   + +       Q ER++I  E
Sbjct: 126 GHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWE 185

Query: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600
           F+QL   L   E R L RLEE +    +    A  +       +  LI+ +E + Q  T 
Sbjct: 186 FEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTR 245

Query: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFH----------------APDLSRMLQMF 644
           ELLQD+   +  +E  R+ +P +    L+   H                   +   ++  
Sbjct: 246 ELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKI 305

Query: 645 RELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWP-----FQCYNYGVL 693
           +EL   + Y VDVTL+      +L+LS++ RQV        +P  P     F C    VL
Sbjct: 306 QELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC----VL 361

Query: 694 GSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWV 753
           GS  F +G+HYWEV+V  K  W +GV C         V R+            P  G+W 
Sbjct: 362 GSPCFIAGRHYWEVEVGDKAKWTIGV-CE------DSVCRKGG------VTSAPQNGFWA 408

Query: 754 IGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKF 813
           + L     YG    +L+S   +  L +  P  RVG+FLDY+AG VSF+NVT      + F
Sbjct: 409 VSLW----YGKEYWALTS--PMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTF 461

Query: 814 SKCCFSQPVYPYF----NPWNCPAPMTLCPPS 841
           S   F  PV PYF    +     AP+ +CP S
Sbjct: 462 SHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493



 Score =  159 bits (402), Expect = 1e-38
 Identities = 94/271 (34%), Positives = 145/271 (53%), Gaps = 10/271 (3%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96
           +++E TCP+CL+   EP+ +DCGH+ C AC+      +    E   SCP C+ ++   ++
Sbjct: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQCRETFPQRHM 65

Query: 97  RPNRHLANI---VRRLR-EVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 152
           RPNRHLAN+   V++LR E   GPG ++   +C  H E L+L+C+ED   IC +C+RS+E
Sbjct: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMG--VCEKHREPLKLYCEEDQMPICVVCDRSRE 123

Query: 153 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 212
           HRGH    +EE  + ++E+ Q  L  LK  +   ++  A   + +    +  + ER +I 
Sbjct: 124 HRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIV 183

Query: 213 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGS 272
            EF QL + L   E R L +LE+ +      I  A          L  LI+ LE + Q  
Sbjct: 184 WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQP 243

Query: 273 TMELLQDVSDVTERSEFWTLRKPEALPTKLR 303
           T ELLQD+ D   R+E   + +P   P  L+
Sbjct: 244 TRELLQDIGDTLSRAERIRIPEPWITPPDLQ 274


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  229 bits (585), Expect = 6e-60
 Identities = 165/529 (31%), Positives = 264/529 (49%), Gaps = 64/529 (12%)

Query: 352 SSAMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCP 411
           S+A  +  L N+Q E +C +CLE L EP+ ++CGH+ C+ACIT   ++          CP
Sbjct: 12  SAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDF----PCP 67

Query: 412 VCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICW 471
           VC  +  +  L+ N+ L ++VE  K+++      +   LC  H E L LFC ED++ +C 
Sbjct: 68  VCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCL 127

Query: 472 LCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQ 531
           +C  S  HR H  V  ++  +E +EKLQ  L+ L+++ +E  + ++   ++    K  V+
Sbjct: 128 ICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVE 187

Query: 532 TERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDV 591
           + RQ+I  EF++L   L+ E+Q  L RLEEEE+  L +  E    L  +++ +  L ++V
Sbjct: 188 SRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEV 247

Query: 592 ECRSQWSTMELLQDMSGIMKWS-------------------------EIWRLKKPKMVSK 626
           E +   S  E+L+D+   ++ +                         EI R +K K +  
Sbjct: 248 EGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEV 307

Query: 627 KLKTVFHAPDLSRMLQMFRELTAVRCYWV-DVTLNSVNLNLNLVLSEDQRQVISV----- 680
              ++    + S   + +  L  +    + DVTL+    + NLVLSED++ V  V     
Sbjct: 308 TSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLR 367

Query: 681 --PIWPFQCYNYG-VLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCAN 737
             P  P +   Y  VL ++ F+SG+HYWEV+V  KT W +G            V R   +
Sbjct: 368 DLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVG------------VCRDSVS 415

Query: 738 RQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGI 797
           R+   T   P  GYW + L N  KY       ++      L + V P RVG+FLDYEAG 
Sbjct: 416 RKGELTPL-PETGYWRVRLWNGDKYA------ATTTPFTPLHIKVKPKRVGIFLDYEAGT 468

Query: 798 VSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW-----NCPAPMTLCPPS 841
           +SF+NVT   S IY F+   F++ ++P F P         AP+T+ PP+
Sbjct: 469 LSFYNVTDR-SHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRPPT 515



 Score =  162 bits (410), Expect = 1e-39
 Identities = 92/268 (34%), Positives = 147/268 (54%), Gaps = 6/268 (2%)

Query: 20  QAGARRVATMTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQE 79
           +AGA   A  T+  L +++ E +C +CLE L EP+ I+CGH+FC+ACIT    +     E
Sbjct: 8   EAGAS--AASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----E 61

Query: 80  GERSCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQED 139
            +  CPVC+ + +  +LRPNR L ++V   +++     K     LC  H E L LFC ED
Sbjct: 62  RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYED 121

Query: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199
            + +C +C  S  HR H    +++  QEY+EK Q+ L+ L+ + QE  +  +   +K   
Sbjct: 122 QEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGE 181

Query: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259
            K  +E  R +I  EF +L   LD  +Q  L +LE+EE+  L+ + E    L  + + L 
Sbjct: 182 LKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLA 241

Query: 260 ELISDLERRCQGSTMELLQDVSDVTERS 287
            L +++E +C  S  E+L+DV    E++
Sbjct: 242 HLAAEVEGKCLQSGFEMLKDVKSTLEKN 269


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  207 bits (528), Expect = 3e-53
 Identities = 153/488 (31%), Positives = 241/488 (49%), Gaps = 51/488 (10%)

Query: 356 ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMG-----GKSSC 410
           A ++   +QEE TC ICL+  T+P+   CGH+ CRACI +S ++A    G     G   C
Sbjct: 3   AVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPC 62

Query: 411 PVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVIC 470
           P C       +L  N+ L  + E  ++        +K+DLC  H E L LFC++D+  IC
Sbjct: 63  PECREMSPQRNLLPNRLLTKVAEMAQQ----HPGLQKQDLCQEHHEPLKLFCQKDQSPIC 118

Query: 471 WLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQV 530
            +C  S+EHR H  +  EE  +  + KL+  ++ L+++      L+A   +    W+ +V
Sbjct: 119 VVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKV 178

Query: 531 QTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISD 590
           +  R+RI  EF+++   L  EEQR LQ LE EE++T  +  E+   L +Q   +  L+  
Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238

Query: 591 VECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMV-SKKLKTVFHAPDLSRMLQMFRELTA 649
           +E RS    +++LQDM   +       ++ P++    + +TV   P    +L+ F E   
Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLE--- 295

Query: 650 VRCYWVDVTLNSVNLNLNLVL--SEDQRQVISVPIWP-------FQCYNYGVLGSQYFSS 700
                 DV  ++ +    L+L  S  +R + S P          F  Y   V G   FSS
Sbjct: 296 ------DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSS 348

Query: 701 GKHYWEV--DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQN 758
           G+HYWEV  +++    W LGV     SR  K  V +C           P  G+WV+ L  
Sbjct: 349 GRHYWEVGMNITGDALWALGVCRDNVSR--KDRVPKC-----------PENGFWVVQLSK 395

Query: 759 KCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 818
             KY      LS+   +  + +  PP  +G+FLD+EAG VSF++V S GS ++ +S+  F
Sbjct: 396 GTKY------LSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSV-SDGSHLHTYSQATF 448

Query: 819 SQPVYPYF 826
             P+ P+F
Sbjct: 449 PGPLQPFF 456



 Score =  161 bits (408), Expect = 2e-39
 Identities = 105/313 (33%), Positives = 157/313 (50%), Gaps = 17/313 (5%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 90
           ++EE TC ICL+  T+P+   CGH+FC+ACI  +  E   G++G R       CP C+  
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68

Query: 91  YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
               NL PNR L  +    ++    PG Q K  LC +H E L+LFCQ+D   IC +C  S
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
           +EHR H     EE  Q Y+ K +E ++ L+ +      L A   +    W+ +++  R R
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           I  EF ++   L   EQR L+ LE EE++    + E+   L  Q  SL  L+  LE R  
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244

Query: 271 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLR-----VCRELTDV 324
              +++LQD+ +   R    +++ PE A PT+ R++ R P    +LR     V  + T  
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSA 304

Query: 325 QSYWAIQGSLTRR 337
             Y  +  S  RR
Sbjct: 305 YPYLLLYESRQRR 317


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  207 bits (528), Expect = 3e-53
 Identities = 153/488 (31%), Positives = 241/488 (49%), Gaps = 51/488 (10%)

Query: 356 ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMG-----GKSSC 410
           A ++   +QEE TC ICL+  T+P+   CGH+ CRACI +S ++A    G     G   C
Sbjct: 3   AVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPC 62

Query: 411 PVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVIC 470
           P C       +L  N+ L  + E  ++        +K+DLC  H E L LFC++D+  IC
Sbjct: 63  PECREMSPQRNLLPNRLLTKVAEMAQQ----HPGLQKQDLCQEHHEPLKLFCQKDQSPIC 118

Query: 471 WLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQV 530
            +C  S+EHR H  +  EE  +  + KL+  ++ L+++      L+A   +    W+ +V
Sbjct: 119 VVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKV 178

Query: 531 QTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISD 590
           +  R+RI  EF+++   L  EEQR LQ LE EE++T  +  E+   L +Q   +  L+  
Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238

Query: 591 VECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMV-SKKLKTVFHAPDLSRMLQMFRELTA 649
           +E RS    +++LQDM   +       ++ P++    + +TV   P    +L+ F E   
Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLE--- 295

Query: 650 VRCYWVDVTLNSVNLNLNLVL--SEDQRQVISVPIWP-------FQCYNYGVLGSQYFSS 700
                 DV  ++ +    L+L  S  +R + S P          F  Y   V G   FSS
Sbjct: 296 ------DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAV-GQTAFSS 348

Query: 701 GKHYWEV--DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQN 758
           G+HYWEV  +++    W LGV     SR  K  V +C           P  G+WV+ L  
Sbjct: 349 GRHYWEVGMNITGDALWALGVCRDNVSR--KDRVPKC-----------PENGFWVVQLSK 395

Query: 759 KCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 818
             KY      LS+   +  + +  PP  +G+FLD+EAG VSF++V S GS ++ +S+  F
Sbjct: 396 GTKY------LSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSV-SDGSHLHTYSQATF 448

Query: 819 SQPVYPYF 826
             P+ P+F
Sbjct: 449 PGPLQPFF 456



 Score =  161 bits (408), Expect = 2e-39
 Identities = 105/313 (33%), Positives = 157/313 (50%), Gaps = 17/313 (5%)

Query: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS------CPVCQTS 90
           ++EE TC ICL+  T+P+   CGH+FC+ACI  +  E   G++G R       CP C+  
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW-EKARGKKGRRKRKGSFPCPECREM 68

Query: 91  YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
               NL PNR L  +    ++    PG Q K  LC +H E L+LFCQ+D   IC +C  S
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQ---HPGLQ-KQDLCQEHHEPLKLFCQKDQSPICVVCRES 124

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
           +EHR H     EE  Q Y+ K +E ++ L+ +      L A   +    W+ +++  R R
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           I  EF ++   L   EQR L+ LE EE++    + E+   L  Q  SL  L+  LE R  
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244

Query: 271 GSTMELLQDVSDVTERSEFWTLRKPE-ALPTKLRSMFRAPDLKRMLR-----VCRELTDV 324
              +++LQD+ +   R    +++ PE A PT+ R++ R P    +LR     V  + T  
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSA 304

Query: 325 QSYWAIQGSLTRR 337
             Y  +  S  RR
Sbjct: 305 YPYLLLYESRQRR 317


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  193 bits (491), Expect = 5e-49
 Identities = 154/505 (30%), Positives = 236/505 (46%), Gaps = 66/505 (13%)

Query: 362 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 421
           ++QEE+TCPICL+   +P+S++CGH+ CR C+  +        GG   CP C    +   
Sbjct: 5   DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60

Query: 422 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 481
           L+ N  LA + E+ +  +L P       LC  H E L LFC++D++ +C +C  SQEH+ 
Sbjct: 61  LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 482 HHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEF 541
           H     +E F+  +EKL    + L  + ++   L+    +  T WK +++++R RI TEF
Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177

Query: 542 DQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTME 601
            +L + L  EE   LQRL +EE++T  K  E   +L Q    +++LI +V  +SQ  T+E
Sbjct: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237

Query: 602 LLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNS 661
           LLQ+   ++  SEI  +    + + K+KTV   P +  ML+ F+         V V L  
Sbjct: 238 LLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIPLMKEMLKRFQ---------VAVNLAE 287

Query: 662 VNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY--------------------GVLGSQ 696
              +  LV S++ R V    S   WP     +NY                     VLG  
Sbjct: 288 DTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKN 347

Query: 697 YFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVR-RCANRQNLYTKYRPLFGYWVIG 755
            F+SGKHYWEV+        +GV CR     M    R + +    ++  Y    GYW + 
Sbjct: 348 VFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGITDRSKMSPDVGIWAIYWSAAGYWPL- 403

Query: 756 LQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSK 815
                  G        +P +          RVGV+LD   G VSF++    G  ++ FS 
Sbjct: 404 ------IGFPGTPTQQEPAL---------HRVGVYLDRGTGNVSFYSAVD-GVHLHTFS- 446

Query: 816 CCFSQPVYPYFNPWNCPAPMTLCPP 840
           C     + P+F  W  P    + PP
Sbjct: 447 CSSVSRLRPFF--WLSPLASLVIPP 469



 Score =  171 bits (432), Expect = 3e-42
 Identities = 97/282 (34%), Positives = 159/282 (56%), Gaps = 10/282 (3%)

Query: 36  DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95
           DI+EE+TCPICL+   +P+SI+CGH+FC+ C+  N         G   CP C+    P  
Sbjct: 5   DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60

Query: 96  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
           LRPN  LA +  + +   LGP   +   LC  H E L+LFC++D + +C +C  SQEH+ 
Sbjct: 61  LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215
           H    ++E  + Y+EK  +S + L  + ++   L     +  T WK++++ +R RI TEF
Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177

Query: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275
           ++L N L   E   L++L +EE++  + + E    L     SL++LI ++  + Q  T+E
Sbjct: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237

Query: 276 LLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRAPDLKRMLR 316
           LLQ+  +V  RSE   +    EA+  K++++ + P +K ML+
Sbjct: 238 LLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQIPLMKEMLK 277


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  192 bits (487), Expect = 1e-48
 Identities = 140/495 (28%), Positives = 240/495 (48%), Gaps = 55/495 (11%)

Query: 360 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 419
           L  +Q E  C ICL+ L++P++++CGH+ CR+CI    +++   +     CPVC      
Sbjct: 7   LTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCI----QQSWLDLQELFPCPVCRHQCQE 62

Query: 420 EHLQANQHLANIVERLKEVKLSPDNGKKRD---LCDHHGEKLLLFCKEDRKVICWLCERS 476
            H ++N  L  ++E  K ++ +  N +K++   LC+ H + L +FCKED  V+C LC + 
Sbjct: 63  GHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQP 122

Query: 477 QEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQR 536
            +H+GHH    E+     +++  + ++ LKK+  + +KL +   ++    +  V+ +RQ 
Sbjct: 123 PDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE 182

Query: 537 IQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQ 596
           + +EF+ L   L+ E+Q  L RL EEEK    K +            ++  +S V   S+
Sbjct: 183 LSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSE 242

Query: 597 WSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKT--VFHAPDLSRMLQMFRELTAVRCYW 654
            S +ELL   S I  + E      P + S  LK       P  S + ++ ++      + 
Sbjct: 243 LSELELL---SQIKIFYESENESSPSIFSIHLKRDGCSFPPQYSALQRIIKK------FK 293

Query: 655 VDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQ-CYNYGVLGSQYFSSGKHYWEV 707
           V++ L+    + NL++SED+++V        VP +P +      VLG  YF SG+H+WE+
Sbjct: 294 VEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEI 353

Query: 708 DVSKKTAWILGVYCR----TYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG 763
           +V  K+ W +G+ C+    T +R      + C                W I LQ+    G
Sbjct: 354 EVGDKSEWAIGI-CKDSLPTKARRPSSAQQEC----------------WRIELQDD---G 393

Query: 764 VFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVY 823
                    P    L + V    +G+FLDYE G +SF+N+ +  S I  F+   F+ P+ 
Sbjct: 394 YHAPGAFPTP----LLLEVKARAIGIFLDYEMGEISFYNM-AEKSHICTFTD-TFTGPLR 447

Query: 824 PYFNPWNCPAPMTLC 838
           PYF       P+ +C
Sbjct: 448 PYFYVGPDSQPLRIC 462



 Score =  141 bits (356), Expect = 2e-33
 Identities = 74/250 (29%), Positives = 134/250 (53%), Gaps = 7/250 (2%)

Query: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93
           L  ++ E  C ICL+ L++P++I+CGH+FC++CI    ++S +  +    CPVC+   Q 
Sbjct: 7   LTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCI----QQSWLDLQELFPCPVCRHQCQE 62

Query: 94  GNLRPNRHLANIV---RRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150
           G+ R N  L  ++   + L+       KQ +  LC  H + L +FC+ED  V+C LC + 
Sbjct: 63  GHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQP 122

Query: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
            +H+GHH   +E+ A  Y+++F   ++ LK +  + +KL +   +K    +  +E +R  
Sbjct: 123 PDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE 182

Query: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270
           + +EF  L   LDR +Q  L +L +EEK   + +        + + +L+  +S +    +
Sbjct: 183 LSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSE 242

Query: 271 GSTMELLQDV 280
            S +ELL  +
Sbjct: 243 LSELELLSQI 252


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  191 bits (486), Expect = 2e-48
 Identities = 148/499 (29%), Positives = 248/499 (49%), Gaps = 53/499 (10%)

Query: 359 ILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYS 418
           ++ N++EE+TC ICL+  + P++ +CGHS C  C+  S +E  T +    SCP C  +  
Sbjct: 6   LMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPL----SCPECWRTLE 61

Query: 419 FEHLQANQ---HLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCER 475
             H Q+N+    LA+I  +L+   L  ++ +          K L   ++           
Sbjct: 62  GPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFV----- 116

Query: 476 SQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQ 535
           +Q H  +   L+ E  +  +EKLQ +L  L+   +EA+ +    +E     + + +T +Q
Sbjct: 117 AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQ 176

Query: 536 RIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRS 595
            + +E+ ++   L  EEQ +LQ LE+EEK+ + K    E +L QQ + + ++I+ +E  S
Sbjct: 177 VVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSS 236

Query: 596 QWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV 655
           Q S  E L+++ G ++ SE   L+ P+  + +L        ++ M +M R+ +       
Sbjct: 237 QSSAFESLEEVRGALERSEPLLLQCPEATTTELSLC----RITGMKEMLRKFS------T 286

Query: 656 DVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQC-YNYGVLGSQYFSSGKHYWEVD 708
           ++TL+    N  LVLSED + V        +P  P +   +  VLG+Q F+SG+HYWEV+
Sbjct: 287 EITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVE 346

Query: 709 VSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEES 768
           V  KT W +G+   + SR           + NL      LF   +IGL+    Y ++  S
Sbjct: 347 VGNKTEWEVGICKDSVSR-----------KGNLPKPPGDLFS--LIGLKIGDDYSLWVSS 393

Query: 769 LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNP 828
                 V       P C+VGVFLDYE+G ++F+N T   SLIY F +  F + + P F+P
Sbjct: 394 PLKGQHV-----REPVCKVGVFLDYESGHIAFYNGTDE-SLIYSFPQASFQEALRPIFSP 447

Query: 829 -----WNCPAPMTLCPPSS 842
                     P+T+C  +S
Sbjct: 448 CLPNEGTNTDPLTICSLNS 466



 Score =  127 bits (320), Expect = 3e-29
 Identities = 86/290 (29%), Positives = 145/290 (50%), Gaps = 13/290 (4%)

Query: 30  TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQT 89
           T+ ++ ++REE+TC ICL+  + P++ +CGHSFC  C+  +  E         SCP C  
Sbjct: 3   TADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEE----HNTPLSCPECWR 58

Query: 90  SYQPGNLRPNRHL---ANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWL 146
           + +  + + N  L   A+I R+LR  VL    +  +        K     ++ G      
Sbjct: 59  TLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFV-- 116

Query: 147 CERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEP 206
              +Q H  +   L  E  + ++EK QE L  L+   +EA+ +    +E+    + + + 
Sbjct: 117 ---AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKT 173

Query: 207 ERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLE 266
            +  + +E+ ++   L   EQ +L+ LEQEEK+ +R +   E  L  Q +SL ++I+ +E
Sbjct: 174 CKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIE 233

Query: 267 RRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316
              Q S  E L++V    ERSE   L+ PEA  T+L S+ R   +K MLR
Sbjct: 234 SSSQSSAFESLEEVRGALERSEPLLLQCPEATTTEL-SLCRITGMKEMLR 282


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score =  190 bits (483), Expect = 4e-48
 Identities = 141/482 (29%), Positives = 235/482 (48%), Gaps = 48/482 (9%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           M S  L   Q E+ C IC+    +P+++DCGHS CR C+ + ++E    M     CP C 
Sbjct: 1   MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPM----RCPSCR 56

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473
            +    +   N  L  +    ++ +  P N    D +C  H E   LFC+ D++++C  C
Sbjct: 57  KTSEKPNFNTNLVLKKLSSLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSW---KYQV 530
             S EH  H         +EC+EKL   +K +    E  ++   ++ +E +++   K  V
Sbjct: 115 SESPEHMAHSHSPIGWAAEECREKL---IKEMDYLWEINQETRNNLNQETSTFHSLKDYV 171

Query: 531 QTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISD 590
              ++ I  ++ ++   L+ EEQR LQ LE E ++   +  +++  + Q  + ++++  +
Sbjct: 172 SVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRE 231

Query: 591 VECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAV 650
           +        + LLQD+  +   +++ +++KP+ V+ +L T +    +  ML  FR     
Sbjct: 232 LWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPEL-TSWCITGVLDMLNNFR----- 285

Query: 651 RCYWVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHY 704
               VD  L++  +   + LSED R VI      S P  P    ++ V G+Q F+SGKHY
Sbjct: 286 ----VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHY 341

Query: 705 WEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 764
           WEVDV+  + WILGV   + +    +V+                  +++I  +    Y  
Sbjct: 342 WEVDVTLSSNWILGVCRDSRTADANFVIDSDER-------------FFLISSKRSNHY-- 386

Query: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824
              SLS++   L   +  P  RVGVFLDY+ G VSFF+V S GSLIY F    FS P+ P
Sbjct: 387 ---SLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRP 442

Query: 825 YF 826
           +F
Sbjct: 443 FF 444



 Score =  115 bits (289), Expect = 1e-25
 Identities = 71/279 (25%), Positives = 133/279 (47%), Gaps = 11/279 (3%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S  L   + E+ C IC+    +P++IDCGHSFC+ C+     E          CP C+
Sbjct: 1   MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG----RAPMRCPSCR 56

Query: 89  TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145
            + +  N   N   + L+++ R+ R   +     +    C  H E  +LFC+ D +++C 
Sbjct: 57  KTSEKPNFNTNLVLKKLSSLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112

Query: 146 LCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQME 205
            C  S EH  H    +   A+E +EK  + +  L    QE             S K+ + 
Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVS 172

Query: 206 PERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDL 265
             +  I  ++ ++   LD  EQR L+ LE+E ++  + +++++  +    + ++++  +L
Sbjct: 173 VRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYREL 232

Query: 266 ERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304
              C    + LLQDV +V+ R++   ++KP+ +  +L S
Sbjct: 233 WETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPELTS 271


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score =  189 bits (480), Expect = 9e-48
 Identities = 141/479 (29%), Positives = 228/479 (47%), Gaps = 42/479 (8%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           M S  L   Q E+ C IC+    +P+++DCGHS CR C+ + ++E    M     CP C 
Sbjct: 1   MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPM----RCPSCR 56

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473
                 +   N  L  +    ++ +  P N    D +C  H E   LFC+ D++++C  C
Sbjct: 57  KISEKPNFNTNVVLKKLSSLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533
             S EH  H         +EC+EKL   +  L +  +E             S K  V   
Sbjct: 115 SESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVR 174

Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593
           ++ I  ++ ++   L+ EEQR LQ LE E ++   +  +++  + Q  + ++++  ++  
Sbjct: 175 KRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWE 234

Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653
                 +ELLQD+  +   +++ +++KP+ V+ +L T +    +  ML  FR        
Sbjct: 235 TCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPEL-TSWCITGVLDMLNNFR-------- 285

Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707
            VD  L++  +   + LSED R VI      S P  P    ++ V G+Q F+SGKHYWEV
Sbjct: 286 -VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEV 344

Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767
           DV+  + WILGV   + +    +V+                  +++I  +    Y     
Sbjct: 345 DVTLSSNWILGVCQDSRTADANFVIDSDER-------------FFLISSKRSNHY----- 386

Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826
           SLS++   L   +  P  +VGVFLDY+ G VSFF+V S GSLIY F    FS P+ P+F
Sbjct: 387 SLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 444



 Score =  117 bits (293), Expect = 4e-26
 Identities = 72/279 (25%), Positives = 133/279 (47%), Gaps = 11/279 (3%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S  L   + E+ C IC+    +P++IDCGHSFC+ C+     E          CP C+
Sbjct: 1   MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG----RAPMRCPSCR 56

Query: 89  TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145
              +  N   N   + L+++ R+ R   +     +    C  H E  +LFC+ D +++C 
Sbjct: 57  KISEKPNFNTNVVLKKLSSLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112

Query: 146 LCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQME 205
            C  S EH  H    +   A+E +EK  + +  L    QE             S K+ + 
Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVS 172

Query: 206 PERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDL 265
             +  I  ++ ++   LD  EQR L+ LE+E ++  + +++++  +    + ++++  +L
Sbjct: 173 VRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYREL 232

Query: 266 ERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304
              C    +ELLQDV +V+ R++   ++KP+ +  +L S
Sbjct: 233 WETCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPELTS 271


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  187 bits (476), Expect = 3e-47
 Identities = 143/479 (29%), Positives = 232/479 (48%), Gaps = 44/479 (9%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           M S  L   Q E+ C IC+    +P++ DC HS CR C+ + ++E    M     CP+C 
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPM----RCPLCR 56

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473
                 +   N  L  +    ++ +  P N    D +C  H E   LFC+ D++++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533
             S EH  H         +EC  ++Q ++K +    +  ++ + ++ +E + +   V+ +
Sbjct: 115 SESPEHMAHSHSPIGWAAEEC--RVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVEDK 172

Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593
           R RI   + ++   L+ EEQR LQ LE E K+   +  +++  + Q  + ++++  ++  
Sbjct: 173 RNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWE 232

Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653
                 +ELLQD+  I   +++ ++ KP+ V+ +L T +    +  ML  FR        
Sbjct: 233 TYHMPDVELLQDVGNISARTDLAQMPKPQPVNPEL-TSWCITGVLDMLNNFR-------- 283

Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707
            VD  L++      + LSED R+VI      S P+ P    ++ V  +Q F+SGKHYWEV
Sbjct: 284 -VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEV 342

Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767
           DV+  + WILGV CR           R A+   +    +  F    I  +    Y     
Sbjct: 343 DVTHSSNWILGV-CRD---------SRTADTNIVIDSDKTFFS---ISSKTSNHY----- 384

Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826
           SLS++   L   +  P   VGVFLDY+ G VSFF+V S GSLIY F    FS P+ P+F
Sbjct: 385 SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 442



 Score =  111 bits (278), Expect = 2e-24
 Identities = 70/280 (25%), Positives = 136/280 (48%), Gaps = 15/280 (5%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S  L   + E+ C IC+    +P++ DC HSFC+ C+     E          CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 89  TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145
              +  N   N   + LA++ R+ R   +     +    C  H E  +LFC+ D +++C 
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112

Query: 146 LCERSQEHRGHHTFLVEEVAQEYQ-EKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQM 204
            C  S EH  H    +   A+E + +K  + +  L    QE +     + ++ + + + +
Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNN---LNQETSKFCSLV 169

Query: 205 EPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISD 264
           E +R RI   + ++   LD  EQR L+ LE+E K+  + +++++  +    + ++++  +
Sbjct: 170 EDKRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRE 229

Query: 265 LERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304
           L        +ELLQDV +++ R++   + KP+ +  +L S
Sbjct: 230 LWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTS 269


>gi|239750044 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  187 bits (476), Expect = 3e-47
 Identities = 143/479 (29%), Positives = 232/479 (48%), Gaps = 44/479 (9%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           M S  L   Q E+ C IC+    +P++ DC HS CR C+ + ++E    M     CP+C 
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPM----RCPLCR 56

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473
                 +   N  L  +    ++ +  P N    D +C  H E   LFC+ D++++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533
             S EH  H         +EC  ++Q ++K +    +  ++ + ++ +E + +   V+ +
Sbjct: 115 SESPEHMAHSHSPIGWAAEEC--RVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVEDK 172

Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593
           R RI   + ++   L+ EEQR LQ LE E K+   +  +++  + Q  + ++++  ++  
Sbjct: 173 RNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWE 232

Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653
                 +ELLQD+  I   +++ ++ KP+ V+ +L T +    +  ML  FR        
Sbjct: 233 TYHMPDVELLQDVGNISARTDLAQMPKPQPVNPEL-TSWCITGVLDMLNNFR-------- 283

Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707
            VD  L++      + LSED R+VI      S P+ P    ++ V  +Q F+SGKHYWEV
Sbjct: 284 -VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEV 342

Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767
           DV+  + WILGV CR           R A+   +    +  F    I  +    Y     
Sbjct: 343 DVTHSSNWILGV-CRD---------SRTADTNIVIDSDKTFFS---ISSKTSNHY----- 384

Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826
           SLS++   L   +  P   VGVFLDY+ G VSFF+V S GSLIY F    FS P+ P+F
Sbjct: 385 SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 442



 Score =  111 bits (278), Expect = 2e-24
 Identities = 70/280 (25%), Positives = 136/280 (48%), Gaps = 15/280 (5%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S  L   + E+ C IC+    +P++ DC HSFC+ C+     E          CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 89  TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145
              +  N   N   + LA++ R+ R   +     +    C  H E  +LFC+ D +++C 
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112

Query: 146 LCERSQEHRGHHTFLVEEVAQEYQ-EKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQM 204
            C  S EH  H    +   A+E + +K  + +  L    QE +     + ++ + + + +
Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNN---LNQETSKFCSLV 169

Query: 205 EPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISD 264
           E +R RI   + ++   LD  EQR L+ LE+E K+  + +++++  +    + ++++  +
Sbjct: 170 EDKRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRE 229

Query: 265 LERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304
           L        +ELLQDV +++ R++   + KP+ +  +L S
Sbjct: 230 LWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTS 269


>gi|239744355 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 447

 Score =  187 bits (476), Expect = 3e-47
 Identities = 143/479 (29%), Positives = 232/479 (48%), Gaps = 44/479 (9%)

Query: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
           M S  L   Q E+ C IC+    +P++ DC HS CR C+ + ++E    M     CP+C 
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPM----RCPLCR 56

Query: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD-LCDHHGEKLLLFCKEDRKVICWLC 473
                 +   N  L  +    ++ +  P N    D +C  H E   LFC+ D++++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533
             S EH  H         +EC  ++Q ++K +    +  ++ + ++ +E + +   V+ +
Sbjct: 115 SESPEHMAHSHSPIGWAAEEC--RVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVEDK 172

Query: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593
           R RI   + ++   L+ EEQR LQ LE E K+   +  +++  + Q  + ++++  ++  
Sbjct: 173 RNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWE 232

Query: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653
                 +ELLQD+  I   +++ ++ KP+ V+ +L T +    +  ML  FR        
Sbjct: 233 TYHMPDVELLQDVGNISARTDLAQMPKPQPVNPEL-TSWCITGVLDMLNNFR-------- 283

Query: 654 WVDVTLNSVNLNLNLVLSEDQRQVI------SVPIWPFQCYNYGVLGSQYFSSGKHYWEV 707
            VD  L++      + LSED R+VI      S P+ P    ++ V  +Q F+SGKHYWEV
Sbjct: 284 -VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEV 342

Query: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767
           DV+  + WILGV CR           R A+   +    +  F    I  +    Y     
Sbjct: 343 DVTHSSNWILGV-CRD---------SRTADTNIVIDSDKTFFS---ISSKTSNHY----- 384

Query: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 826
           SLS++   L   +  P   VGVFLDY+ G VSFF+V S GSLIY F    FS P+ P+F
Sbjct: 385 SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDV-SKGSLIYGFPPSSFSSPLRPFF 442



 Score =  111 bits (278), Expect = 2e-24
 Identities = 70/280 (25%), Positives = 136/280 (48%), Gaps = 15/280 (5%)

Query: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
           M S  L   + E+ C IC+    +P++ DC HSFC+ C+     E          CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 89  TSYQPGNLRPN---RHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICW 145
              +  N   N   + LA++ R+ R   +     +    C  H E  +LFC+ D +++C 
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTRPQNINSSDNI----CVLHEETKELFCEADKRLLCG 112

Query: 146 LCERSQEHRGHHTFLVEEVAQEYQ-EKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQM 204
            C  S EH  H    +   A+E + +K  + +  L    QE +     + ++ + + + +
Sbjct: 113 PCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNN---LNQETSKFCSLV 169

Query: 205 EPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISD 264
           E +R RI   + ++   LD  EQR L+ LE+E K+  + +++++  +    + ++++  +
Sbjct: 170 EDKRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRE 229

Query: 265 LERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS 304
           L        +ELLQDV +++ R++   + KP+ +  +L S
Sbjct: 230 LWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTS 269


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,302,933
Number of Sequences: 37866
Number of extensions: 1568393
Number of successful extensions: 17205
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 412
Number of HSP's successfully gapped in prelim test: 886
Number of HSP's that attempted gapping in prelim test: 8794
Number of HSP's gapped (non-prelim): 6235
length of query: 842
length of database: 18,247,518
effective HSP length: 111
effective length of query: 731
effective length of database: 14,044,392
effective search space: 10266450552
effective search space used: 10266450552
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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