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Search of human proteins with 50897854
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo
sapiens]
(487 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens] 982 0.0
gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens] 646 0.0
gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapi... 474 e-134
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 146 5e-35
gi|56119110 family with sequence similarity 13, member A1 isofor... 144 1e-34
gi|62865869 family with sequence similarity 13, member A1 isofor... 144 1e-34
gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] 137 2e-32
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 137 2e-32
gi|118442841 hypothetical protein LOC123591 [Homo sapiens] 38 0.018
gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens] 37 0.031
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 37 0.040
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 37 0.040
gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens] 36 0.090
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 36 0.090
gi|55749424 transcription elongation factor A (SII)-like 1 [Homo... 36 0.090
gi|55749406 transcription elongation factor A (SII)-like 1 [Homo... 36 0.090
gi|55749397 transcription elongation factor A (SII)-like 1 [Homo... 36 0.090
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 35 0.15
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 35 0.15
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 35 0.15
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 35 0.15
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 35 0.15
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 35 0.15
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 35 0.20
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 35 0.20
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 35 0.20
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 35 0.20
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 34 0.34
gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens] 33 0.45
gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens] 33 0.45
>gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]
Length = 487
Score = 982 bits (2539), Expect = 0.0
Identities = 487/487 (100%), Positives = 487/487 (100%)
Query: 1 MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAP 60
MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAP
Sbjct: 1 MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAP 60
Query: 61 PSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSEC 120
PSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSEC
Sbjct: 61 PSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSEC 120
Query: 121 QVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKD 180
QVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKD
Sbjct: 121 QVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKD 180
Query: 181 PAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
PAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR
Sbjct: 181 PAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
Query: 241 CSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKI 300
CSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKI
Sbjct: 241 CSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKI 300
Query: 301 RKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGS 360
RKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGS
Sbjct: 301 RKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGS 360
Query: 361 QQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHL 420
QQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHL
Sbjct: 361 QQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHL 420
Query: 421 RETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISK 480
RETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISK
Sbjct: 421 RETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISK 480
Query: 481 QDVAKTI 487
QDVAKTI
Sbjct: 481 QDVAKTI 487
>gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens]
Length = 585
Score = 646 bits (1667), Expect = 0.0
Identities = 337/410 (82%), Positives = 353/410 (86%), Gaps = 12/410 (2%)
Query: 1 MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAP 60
MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAP
Sbjct: 1 MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAP 60
Query: 61 PSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSEC 120
PSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSEC
Sbjct: 61 PSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSEC 120
Query: 121 QVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKD 180
QVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKD
Sbjct: 121 QVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKD 180
Query: 181 PAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
PAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR
Sbjct: 181 PAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
Query: 241 CSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKI 300
CSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKI
Sbjct: 241 CSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKI 300
Query: 301 RKFEEKFEQEKKYRVTKQDK----NLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDR 356
RKFEEKFEQEKKYR + DK ++K + D + KQ+ L + EE+ S
Sbjct: 301 RKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL---KELKLKLSEEQGSAPKG 357
Query: 357 PQGS---QQPSL-ADPASHLPVGDHLTYSNETEPVRAL-LPDEKKEVKPP 401
P + +QP++ + G + S E P AL E++E PP
Sbjct: 358 PPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPP 407
Score = 351 bits (900), Expect = 1e-96
Identities = 185/234 (79%), Positives = 197/234 (84%), Gaps = 3/234 (1%)
Query: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313
P+ P +Q +PR + + G EP + + T K R+ E+ ++
Sbjct: 355 PKGPPRNLLCEQPTVPRENGKPEAA-GPEPSSSGEETPDAALTCLKERR--EQLPPQEDS 411
Query: 314 RVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 373
+VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP
Sbjct: 412 KVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 471
Query: 374 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA 433
VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA
Sbjct: 472 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA 531
Query: 434 LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487
LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI
Sbjct: 532 LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 585
>gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo
sapiens]
Length = 502
Score = 474 bits (1220), Expect = e-134
Identities = 254/327 (77%), Positives = 270/327 (82%), Gaps = 12/327 (3%)
Query: 84 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 143
MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV
Sbjct: 1 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 60
Query: 144 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 203
RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH
Sbjct: 61 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 120
Query: 204 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 263
KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST
Sbjct: 121 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 180
Query: 264 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDK--- 320
QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYR + DK
Sbjct: 181 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN 240
Query: 321 -NLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGS---QQPSL-ADPASHLPVG 375
++K + D + KQ+ L + EE+ S P + +QP++ + G
Sbjct: 241 PEVLKWMNDLAKGRKQL---KELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAG 297
Query: 376 DHLTYSNETEPVRAL-LPDEKKEVKPP 401
+ S E P AL E++E PP
Sbjct: 298 PEPSSSGEETPDAALTCLKERREQLPP 324
Score = 351 bits (900), Expect = 1e-96
Identities = 185/234 (79%), Positives = 197/234 (84%), Gaps = 3/234 (1%)
Query: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313
P+ P +Q +PR + + G EP + + T K R+ E+ ++
Sbjct: 272 PKGPPRNLLCEQPTVPRENGKPEAA-GPEPSSSGEETPDAALTCLKERR--EQLPPQEDS 328
Query: 314 RVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 373
+VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP
Sbjct: 329 KVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 388
Query: 374 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA 433
VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA
Sbjct: 389 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA 448
Query: 434 LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487
LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI
Sbjct: 449 LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 502
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 146 bits (368), Expect = 5e-35
Identities = 96/261 (36%), Positives = 148/261 (56%), Gaps = 35/261 (13%)
Query: 252 LDPESAPSPPSTQQFMMPRSSS----RCSCGDGKEPQTITQLTK-HIQSLKRKIRKFEEK 306
+ E PS +T + ++ R RC P+ I ++TK H+ K ++K
Sbjct: 665 IQKEKKPSKEATLELILKRLKEKRIERCL------PEDIKKMTKDHLVEEKASLQKSLLY 718
Query: 307 FEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSL 365
+E + VTK++++++KPLYDRYR++KQ+L+ S+ P + S + +G QP +
Sbjct: 719 YESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPII 774
Query: 366 ADPASHL------PVGDHLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMS 406
+H D + S+E V++ L + + +V+ L +S
Sbjct: 775 EGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLS 834
Query: 407 NLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKH 466
+ A+MP LL+ L + RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK
Sbjct: 835 SSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKK 894
Query: 467 IKAKLRLLEVLISKQDVAKTI 487
IKAKLRLLEVLISKQD +K+I
Sbjct: 895 IKAKLRLLEVLISKQDSSKSI 915
Score = 84.7 bits (208), Expect = 2e-16
Identities = 87/306 (28%), Positives = 133/306 (43%), Gaps = 53/306 (17%)
Query: 190 LADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQ 248
++DG +P P K Q +++S L S R+ +H + D P+LS R F QSQ
Sbjct: 473 VSDGDKWEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQ 531
Query: 249 RFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFE 308
RF DPE S F R SS S + +E +T QL K +Q +KIR+FEE+FE
Sbjct: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFE 588
Query: 309 QEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADP 368
+E+ + + D + +++K + L I++ + + D G P
Sbjct: 589 RERNSKPSYSD------IAANPKVLKWMTELTKLRKQIKDAKHKNSD---GEFVPQTRPR 639
Query: 369 ASHLPVG-----DHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRET 423
++ LP DH NE EP ++ EKK K EAT+ ++L L+E
Sbjct: 640 SNTLPKSFGSSLDHEDEENEDEP--KVIQKEKKPSK----------EATLELILKRLKEK 687
Query: 424 R------------------ADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK 465
R +K L+K+L +E Q GR KE+R + Y Y+
Sbjct: 688 RIERCLPEDIKKMTKDHLVEEKASLQKSLLYYESQH----GRPVTKEERHIVKPLYDRYR 743
Query: 466 HIKAKL 471
+K L
Sbjct: 744 LVKQML 749
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 144 bits (364), Expect = 1e-34
Identities = 90/232 (38%), Positives = 132/232 (56%), Gaps = 28/232 (12%)
Query: 279 DGKEPQTITQLTK-HIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQIL 337
+ P+ I +TK I + K ++K +E VTK ++ ++KPLYDRYR++KQIL
Sbjct: 786 ESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQIL 845
Query: 338 S----------------TPSLIPTIQEEEDSD----EDRPQGSQQPSLADPASHLPVGDH 377
S +P L P I+ E S ++ +GS+ S P + +
Sbjct: 846 SRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTD 905
Query: 378 LT-------YSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRL 430
+ + ++ + + + D+ +SNLH A++P LL+HL+E R +KKR+
Sbjct: 906 FSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRI 965
Query: 431 RKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQD 482
RK LR+FE+ FF+Q GR+ QKEDR PMA+EY EYKHIKAKLRLLEVLISK+D
Sbjct: 966 RKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 1017
Score = 116 bits (291), Expect = 4e-26
Identities = 103/330 (31%), Positives = 150/330 (45%), Gaps = 50/330 (15%)
Query: 162 ETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVG 221
+T+Q N++ Q P S + L D + +P P Q E + E S
Sbjct: 540 DTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ 599
Query: 222 TSRLLYHITDGDN-PLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDG 280
RL+ + D D+ P+LSPR + QS+++ D E PSPP++ FM RSSS S D
Sbjct: 600 AGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE 659
Query: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDK----NLIKPLYDRYRIIKQI 336
+E T QLT+ IQSLK+KIRKFE++FE+EKKYR + DK ++K D + +Q+
Sbjct: 660 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 719
Query: 337 LSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKK 396
+ I S+ED +Q S P S G L +E +K+
Sbjct: 720 KESKLKI--------SEEDLTPRMRQRSNTLPKS---FGSQLEKEDE----------KKQ 758
Query: 397 EVKPPALSMSNLHEATMPVLLDHLRETRADKKR------------------LRKALREFE 438
E+ A+ S EAT+ + L+E RA+ R L+KAL +E
Sbjct: 759 ELVDKAIKPS--VEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYE 816
Query: 439 EQFFKQTGRSPQKEDRIPMADEYYEYKHIK 468
GR K +R M Y Y+ +K
Sbjct: 817 SIH----GRPVTKNERQVMKPLYDRYRLVK 842
>gi|62865869 family with sequence similarity 13, member A1 isoform b
[Homo sapiens]
Length = 697
Score = 144 bits (364), Expect = 1e-34
Identities = 90/232 (38%), Positives = 132/232 (56%), Gaps = 28/232 (12%)
Query: 279 DGKEPQTITQLTK-HIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQIL 337
+ P+ I +TK I + K ++K +E VTK ++ ++KPLYDRYR++KQIL
Sbjct: 460 ESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQIL 519
Query: 338 S----------------TPSLIPTIQEEEDSD----EDRPQGSQQPSLADPASHLPVGDH 377
S +P L P I+ E S ++ +GS+ S P + +
Sbjct: 520 SRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTD 579
Query: 378 LT-------YSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRL 430
+ + ++ + + + D+ +SNLH A++P LL+HL+E R +KKR+
Sbjct: 580 FSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRI 639
Query: 431 RKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQD 482
RK LR+FE+ FF+Q GR+ QKEDR PMA+EY EYKHIKAKLRLLEVLISK+D
Sbjct: 640 RKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 691
Score = 116 bits (291), Expect = 4e-26
Identities = 103/330 (31%), Positives = 150/330 (45%), Gaps = 50/330 (15%)
Query: 162 ETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVG 221
+T+Q N++ Q P S + L D + +P P Q E + E S
Sbjct: 214 DTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ 273
Query: 222 TSRLLYHITDGDN-PLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDG 280
RL+ + D D+ P+LSPR + QS+++ D E PSPP++ FM RSSS S D
Sbjct: 274 AGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE 333
Query: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDK----NLIKPLYDRYRIIKQI 336
+E T QLT+ IQSLK+KIRKFE++FE+EKKYR + DK ++K D + +Q+
Sbjct: 334 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 393
Query: 337 LSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKK 396
+ I S+ED +Q S P S G L +E +K+
Sbjct: 394 KESKLKI--------SEEDLTPRMRQRSNTLPKS---FGSQLEKEDE----------KKQ 432
Query: 397 EVKPPALSMSNLHEATMPVLLDHLRETRADKKR------------------LRKALREFE 438
E+ A+ S EAT+ + L+E RA+ R L+KAL +E
Sbjct: 433 ELVDKAIKPS--VEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYE 490
Query: 439 EQFFKQTGRSPQKEDRIPMADEYYEYKHIK 468
GR K +R M Y Y+ +K
Sbjct: 491 SIH----GRPVTKNERQVMKPLYDRYRLVK 516
>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
Length = 791
Score = 137 bits (346), Expect = 2e-32
Identities = 89/227 (39%), Positives = 134/227 (59%), Gaps = 28/227 (12%)
Query: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTP 340
K+P L ++ LK K + E ++ K VTK++++++KPLYDRYR++KQ+L+
Sbjct: 573 KKPSKEATLELILKRLKEK--RIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLTRA 628
Query: 341 SLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEP 386
S+ P + S + +G QP + +H D + S+E
Sbjct: 629 SITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ 684
Query: 387 VRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQ 440
V++ L + + +V+ L +S+ A+MP LL+ L + RA+KK+LRK LREFEE
Sbjct: 685 VQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEA 744
Query: 441 FFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487
F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I
Sbjct: 745 FYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791
Score = 78.2 bits (191), Expect = 2e-14
Identities = 71/239 (29%), Positives = 109/239 (45%), Gaps = 31/239 (12%)
Query: 195 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 253
D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D
Sbjct: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
Query: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313
PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+
Sbjct: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
Query: 314 RVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 373
+ + D + +++K + L I++ + + D G P ++ LP
Sbjct: 498 KPSYSD------IAANPKVLKWMTELTKLRKQIKDAKHKNSD---GEFVPQTRPRSNTLP 548
Query: 374 VG-----DHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK 427
DH NE EP ++ EKK K EAT+ ++L L+E R ++
Sbjct: 549 KSFGSSLDHEDEENEDEP--KVIQKEKKPSK----------EATLELILKRLKEKRIER 595
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 388 RALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK---KRLRKALREFEEQFFKQ 444
R L EK + ALS + + ++ D RE R K+L+K +R+FEEQF ++
Sbjct: 436 RFLHDPEKLDSSSKALSFTRIRRSSFSSK-DEKREDRTPYQLVKKLQKKIRQFEEQFERE 494
Query: 445 TGRSPQKED 453
P D
Sbjct: 495 RNSKPSYSD 503
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 137 bits (346), Expect = 2e-32
Identities = 89/227 (39%), Positives = 134/227 (59%), Gaps = 28/227 (12%)
Query: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTP 340
K+P L ++ LK K + E ++ K VTK++++++KPLYDRYR++KQ+L+
Sbjct: 669 KKPSKEATLELILKRLKEK--RIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLTRA 724
Query: 341 SLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEP 386
S+ P + S + +G QP + +H D + S+E
Sbjct: 725 SITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ 780
Query: 387 VRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQ 440
V++ L + + +V+ L +S+ A+MP LL+ L + RA+KK+LRK LREFEE
Sbjct: 781 VQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEA 840
Query: 441 FFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487
F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I
Sbjct: 841 FYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 887
Score = 79.3 bits (194), Expect = 7e-15
Identities = 72/244 (29%), Positives = 112/244 (45%), Gaps = 31/244 (12%)
Query: 190 LADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQ 248
++DG +P P K Q +++S L S R+ +H + D P+LS R F QSQ
Sbjct: 473 VSDGDKWEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQ 531
Query: 249 RFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFE 308
RF DPE S F R SS S + +E +T QL K +Q +KIR+FEE+FE
Sbjct: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFE 588
Query: 309 QEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADP 368
+E+ + + D + +++K + L I++ + + D G P
Sbjct: 589 RERNSKPSYSD------IAANPKVLKWMTELTKLRKQIKDAKHKNSD---GEFVPQTRPR 639
Query: 369 ASHLPVG-----DHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRET 423
++ LP DH NE EP ++ EKK K EAT+ ++L L+E
Sbjct: 640 SNTLPKSFGSSLDHEDEENEDEP--KVIQKEKKPSK----------EATLELILKRLKEK 687
Query: 424 RADK 427
R ++
Sbjct: 688 RIER 691
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 388 RALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK---KRLRKALREFEEQFFKQ 444
R L EK + ALS + + ++ D RE R K+L+K +R+FEEQF ++
Sbjct: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSK-DEKREDRTPYQLVKKLQKKIRQFEEQFERE 590
Query: 445 TGRSPQKED 453
P D
Sbjct: 591 RNSKPSYSD 599
>gi|118442841 hypothetical protein LOC123591 [Homo sapiens]
Length = 531
Score = 38.1 bits (87), Expect = 0.018
Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 11/110 (10%)
Query: 8 SLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQ 67
S S S ++VT D DCS+ R+E + E P +PP QQ
Sbjct: 383 SATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSSEPGP---------SPPPLPSQQ 433
Query: 68 QNVEATV--LVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVS 115
Q EATV L+ S+ + K+ P + + S S E EH VS
Sbjct: 434 QVEEATVQDLLSSLSEDPCPSQKALDPAPLARPSPAGSAQTSPELEHRVS 483
>gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]
Length = 800
Score = 37.4 bits (85), Expect = 0.031
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 293 IQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIK--PLYDRYRIIKQILSTPSLIPTIQEEE 350
+ + KRK + +K+E+ + T +K LI P+ D+ II Q P + + ++EE
Sbjct: 120 VHAKKRKHERIIDKYEKIPRTLQTAPEKELIHLLPIKDKSGIIPQTREKP-VTDSNKDEE 178
Query: 351 DSDEDRPQGSQQPSLADPASHLPVGDHL 378
D +E+R ++ + DP L + +HL
Sbjct: 179 DQEEEREL--EEEIIEDPIQELTIEEHL 204
Score = 30.4 bits (67), Expect = 3.8
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 14/79 (17%)
Query: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQ-----------EKKYRVTKQDKNLIKPLYDR 329
K+ T + K + ++RK +K EEK E+ EKK ++ + N++ Y
Sbjct: 445 KKFMTFKEKRKSLSRMQRKWKKAEEKLERELREAEASESTEKKLKLHTETLNIVFVTY-- 502
Query: 330 YRIIKQILSTPSLIPTIQE 348
+RI+K+ +P L+P + E
Sbjct: 503 FRILKKAQRSP-LLPAVLE 520
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 37.0 bits (84), Expect = 0.040
Identities = 59/257 (22%), Positives = 104/257 (40%), Gaps = 54/257 (21%)
Query: 35 DCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKS 94
D S+R E AG +E S + Q+ + L++ PS F+ KS
Sbjct: 219 DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLE---HPSRKIFR----KS 271
Query: 95 IFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTA 154
E RS + T V S +S +N+ ++T QPR D +
Sbjct: 272 RISEEDDRSELDDNNTMEEVKS-------------DSTENS--NSRDTGLSQPRRDSK-G 315
Query: 155 ISPKDAFETRQDLNEEEAAQVHGV------------KDPAPASTQSVLADGT-DSADPSP 201
S +D+ +++L++EE+ V G ++ + S + V+++ D+ DP+
Sbjct: 316 DSQEDS---KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT 372
Query: 202 VHKDGQNEADSAPED-LHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSP 260
+ + Q ++DS+ ED H++ S+ D+ S+ N ES SP
Sbjct: 373 SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADS----------ESSESLNFSEESPESP 422
Query: 261 ----PSTQQFMMPRSSS 273
S+Q+ + SSS
Sbjct: 423 EDENSSSQEGLQSHSSS 439
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 4/117 (3%)
Query: 11 DNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGAL----VEEHAPPSWEPQ 66
DN +T+ E ED S ED + S ++E D+ + E +P S E +
Sbjct: 366 DNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDE 425
Query: 67 QQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVR 123
+ + + S S + +S RS +S TE SS+ + Q++
Sbjct: 426 NSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 482
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 37.0 bits (84), Expect = 0.040
Identities = 59/257 (22%), Positives = 104/257 (40%), Gaps = 54/257 (21%)
Query: 35 DCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSRKPKS 94
D S+R E AG +E S + Q+ + L++ PS F+ KS
Sbjct: 203 DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLE---HPSRKIFR----KS 255
Query: 95 IFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTA 154
E RS + T V S +S +N+ ++T QPR D +
Sbjct: 256 RISEEDDRSELDDNNTMEEVKS-------------DSTENS--NSRDTGLSQPRRDSK-G 299
Query: 155 ISPKDAFETRQDLNEEEAAQVHGV------------KDPAPASTQSVLADGT-DSADPSP 201
S +D+ +++L++EE+ V G ++ + S + V+++ D+ DP+
Sbjct: 300 DSQEDS---KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT 356
Query: 202 VHKDGQNEADSAPED-LHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSP 260
+ + Q ++DS+ ED H++ S+ D+ S+ N ES SP
Sbjct: 357 SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADS----------ESSESLNFSEESPESP 406
Query: 261 ----PSTQQFMMPRSSS 273
S+Q+ + SSS
Sbjct: 407 EDENSSSQEGLQSHSSS 423
Score = 30.4 bits (67), Expect = 3.8
Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 4/117 (3%)
Query: 11 DNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGAL----VEEHAPPSWEPQ 66
DN +T+ E ED S ED + S ++E D+ + E +P S E +
Sbjct: 350 DNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDE 409
Query: 67 QQNVEATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVR 123
+ + + S S + +S RS +S TE SS+ + Q++
Sbjct: 410 NSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 466
>gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]
Length = 506
Score = 35.8 bits (81), Expect = 0.090
Identities = 71/306 (23%), Positives = 118/306 (38%), Gaps = 55/306 (17%)
Query: 176 HGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNP 235
HGV + AS+ S + +DS+ S D + + ++ S +S
Sbjct: 15 HGVAEEEMASSTSDSGEESDSSSSSSSTSDSSSSSSTSGSSSGSGSSS------------ 62
Query: 236 LLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQS 295
S S S R L + PS + P ++ + PQ + + +++
Sbjct: 63 -----SSSGSTSSRSRLYRKKRVPEPSRRARRAPLGTNFVD----RLPQAVRNRVQALRN 113
Query: 296 LKRKIRKFEEKF-----EQEKKYRVTKQDKNLIKPLYD-RYRIIKQILSTPSLIPTIQEE 349
++ + K + F + E+KY L KPLYD R++II PT +E
Sbjct: 114 IQDECDKVDTLFLKAIHDLERKY------AELNKPLYDRRFQII-----NAEYEPTEEEC 162
Query: 350 EDSDEDRPQGSQQPSLADPASHLP--VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSN 407
E + ED S + + S +P G+ E V+A E+KEV P +
Sbjct: 163 EWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEENPKENPEVKA----EEKEV-PKEIPEVK 217
Query: 408 LHEATMPVLLDHLR-ETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKH 466
E +P + ++ E +AD K +A E +E KE AD+ + K
Sbjct: 218 DEEKEVPKEIPEVKAEEKADSKDCMEATPEVKED---------PKEVPQVKADDKEQPKA 268
Query: 467 IKAKLR 472
+AK R
Sbjct: 269 TEAKAR 274
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 35.8 bits (81), Expect = 0.090
Identities = 37/207 (17%), Positives = 76/207 (36%), Gaps = 5/207 (2%)
Query: 11 DNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNV 70
D+S SS + D S D +D S+ D ++ + D+ + +
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 71 EATVLVDSVLRPSMGNFK-----SRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAG 125
+++ DS N S S ++S S S ++ SS S +
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184
Query: 126 TPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPAS 185
+ S +++ ++ D + D+ ++ + ++ + D + +S
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244
Query: 186 TQSVLADGTDSADPSPVHKDGQNEADS 212
S +D +DS+D S D +E+DS
Sbjct: 1245 DSSNSSDSSDSSDSSDSTSDSNDESDS 1271
Score = 29.6 bits (65), Expect = 6.5
Identities = 34/200 (17%), Positives = 70/200 (35%), Gaps = 10/200 (5%)
Query: 11 DNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNV 70
D+S SS + D S D +D S D ++ N D+ + +
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 71 EATVLVDSVLRPSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHE 130
+++ DS S S ++S S S ++ SS S + +
Sbjct: 1146 DSSESSDS----------SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195
Query: 131 SPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVL 190
S +++ ++ D + D+ ++ +++ D + +S S
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255
Query: 191 ADGTDSADPSPVHKDGQNEA 210
+D +DS S D Q+++
Sbjct: 1256 SDSSDSTSDSNDESDSQSKS 1275
>gi|55749424 transcription elongation factor A (SII)-like 1 [Homo
sapiens]
Length = 159
Score = 35.8 bits (81), Expect = 0.090
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 17/140 (12%)
Query: 347 QEEEDSDEDRPQGSQQPSLADP---ASHLPVGDHLTYSNETEPVRALLPDEK-KEVKPP- 401
Q +DE+RP P P +S + + E P LLP+ E +PP
Sbjct: 13 QSAPKTDEERPPVEHSPEKQSPEEQSSEEQSSEEEFFPEELLP--ELLPEMLLSEERPPQ 70
Query: 402 -ALSMSNLHEATMPV------LLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDR 454
LS +L E P+ + H E + K+RL ++ +F GR+ E+
Sbjct: 71 EGLSRKDLFEGRPPMEQPPCGVGKHKLEEGSFKERLARSRPQFRGDIH---GRNLSNEEM 127
Query: 455 IPMADEYYEYKHIKAKLRLL 474
I ADE E K ++ KL ++
Sbjct: 128 IQAADELEEMKRVRNKLMIM 147
>gi|55749406 transcription elongation factor A (SII)-like 1 [Homo
sapiens]
Length = 159
Score = 35.8 bits (81), Expect = 0.090
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 17/140 (12%)
Query: 347 QEEEDSDEDRPQGSQQPSLADP---ASHLPVGDHLTYSNETEPVRALLPDEK-KEVKPP- 401
Q +DE+RP P P +S + + E P LLP+ E +PP
Sbjct: 13 QSAPKTDEERPPVEHSPEKQSPEEQSSEEQSSEEEFFPEELLP--ELLPEMLLSEERPPQ 70
Query: 402 -ALSMSNLHEATMPV------LLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDR 454
LS +L E P+ + H E + K+RL ++ +F GR+ E+
Sbjct: 71 EGLSRKDLFEGRPPMEQPPCGVGKHKLEEGSFKERLARSRPQFRGDIH---GRNLSNEEM 127
Query: 455 IPMADEYYEYKHIKAKLRLL 474
I ADE E K ++ KL ++
Sbjct: 128 IQAADELEEMKRVRNKLMIM 147
>gi|55749397 transcription elongation factor A (SII)-like 1 [Homo
sapiens]
Length = 159
Score = 35.8 bits (81), Expect = 0.090
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 17/140 (12%)
Query: 347 QEEEDSDEDRPQGSQQPSLADP---ASHLPVGDHLTYSNETEPVRALLPDEK-KEVKPP- 401
Q +DE+RP P P +S + + E P LLP+ E +PP
Sbjct: 13 QSAPKTDEERPPVEHSPEKQSPEEQSSEEQSSEEEFFPEELLP--ELLPEMLLSEERPPQ 70
Query: 402 -ALSMSNLHEATMPV------LLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDR 454
LS +L E P+ + H E + K+RL ++ +F GR+ E+
Sbjct: 71 EGLSRKDLFEGRPPMEQPPCGVGKHKLEEGSFKERLARSRPQFRGDIH---GRNLSNEEM 127
Query: 455 IPMADEYYEYKHIKAKLRLL 474
I ADE E K ++ KL ++
Sbjct: 128 IQAADELEEMKRVRNKLMIM 147
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 35.0 bits (79), Expect = 0.15
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 41/263 (15%)
Query: 31 EDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSR 90
E+ ++ SS +++E P A AL++ A S + Q + +S + + +
Sbjct: 259 EEDSESSSEESSDSEEETPAAKALLQAKA--SGKTSQVGAASAPAKESPRKGAAPAPPGK 316
Query: 91 KPKSIFKAESGRSHGESQETEHVVSSQSEC-----------QVRAGT-PAHESPQNNAFK 138
++ KA++G+ +SQ + S+ E QVRA + PA ESP+ A
Sbjct: 317 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 376
Query: 139 C--QETVRLQPRI-----DQRTAISPKDAFETRQDLNEEEAAQVHGV-KDP--APASTQS 188
++T ++ ++ + S +++ R+ L AAQV + K P PAST
Sbjct: 377 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 436
Query: 189 V--LADGTDSADP------SPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
+ L G P +P + G+ E DS S +S DG+ P
Sbjct: 437 MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS-------DGEVPTAVAP 489
Query: 241 CSIFSQSQRFNLDPESAPS--PP 261
S P S+P+ PP
Sbjct: 490 AQEKSLGNILQAKPTSSPAKGPP 512
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 35.0 bits (79), Expect = 0.15
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 41/263 (15%)
Query: 31 EDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSR 90
E+ ++ SS +++E P A AL++ A S + Q + +S + + +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKA--SGKTSQVGAASAPAKESPRKGAAPAPPGK 393
Query: 91 KPKSIFKAESGRSHGESQETEHVVSSQSEC-----------QVRAGT-PAHESPQNNAFK 138
++ KA++G+ +SQ + S+ E QVRA + PA ESP+ A
Sbjct: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453
Query: 139 C--QETVRLQPRI-----DQRTAISPKDAFETRQDLNEEEAAQVHGV-KDP--APASTQS 188
++T ++ ++ + S +++ R+ L AAQV + K P PAST
Sbjct: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
Query: 189 V--LADGTDSADP------SPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
+ L G P +P + G+ E DS S +S DG+ P
Sbjct: 514 MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS-------DGEVPTAVAP 566
Query: 241 CSIFSQSQRFNLDPESAPS--PP 261
S P S+P+ PP
Sbjct: 567 AQEKSLGNILQAKPTSSPAKGPP 589
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 35.0 bits (79), Expect = 0.15
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 41/263 (15%)
Query: 31 EDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSR 90
E+ ++ SS +++E P A AL++ A S + Q + +S + + +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKA--SGKTSQVGAASAPAKESPRKGAAPAPPGK 393
Query: 91 KPKSIFKAESGRSHGESQETEHVVSSQSEC-----------QVRAGT-PAHESPQNNAFK 138
++ KA++G+ +SQ + S+ E QVRA + PA ESP+ A
Sbjct: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453
Query: 139 C--QETVRLQPRI-----DQRTAISPKDAFETRQDLNEEEAAQVHGV-KDP--APASTQS 188
++T ++ ++ + S +++ R+ L AAQV + K P PAST
Sbjct: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
Query: 189 V--LADGTDSADP------SPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
+ L G P +P + G+ E DS S +S DG+ P
Sbjct: 514 MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS-------DGEVPTAVAP 566
Query: 241 CSIFSQSQRFNLDPESAPS--PP 261
S P S+P+ PP
Sbjct: 567 AQEKSLGNILQAKPTSSPAKGPP 589
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 35.0 bits (79), Expect = 0.15
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 41/263 (15%)
Query: 31 EDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSR 90
E+ ++ SS +++E P A AL++ A S + Q + +S + + +
Sbjct: 259 EEDSESSSEESSDSEEETPAAKALLQAKA--SGKTSQVGAASAPAKESPRKGAAPAPPGK 316
Query: 91 KPKSIFKAESGRSHGESQETEHVVSSQSEC-----------QVRAGT-PAHESPQNNAFK 138
++ KA++G+ +SQ + S+ E QVRA + PA ESP+ A
Sbjct: 317 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 376
Query: 139 C--QETVRLQPRI-----DQRTAISPKDAFETRQDLNEEEAAQVHGV-KDP--APASTQS 188
++T ++ ++ + S +++ R+ L AAQV + K P PAST
Sbjct: 377 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 436
Query: 189 V--LADGTDSADP------SPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
+ L G P +P + G+ E DS S +S DG+ P
Sbjct: 437 MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS-------DGEVPTAVAP 489
Query: 241 CSIFSQSQRFNLDPESAPS--PP 261
S P S+P+ PP
Sbjct: 490 AQEKSLGNILQAKPTSSPAKGPP 512
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 35.0 bits (79), Expect = 0.15
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 41/263 (15%)
Query: 31 EDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSR 90
E+ ++ SS +++E P A AL++ A S + Q + +S + + +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKA--SGKTSQVGAASAPAKESPRKGAAPAPPGK 393
Query: 91 KPKSIFKAESGRSHGESQETEHVVSSQSEC-----------QVRAGT-PAHESPQNNAFK 138
++ KA++G+ +SQ + S+ E QVRA + PA ESP+ A
Sbjct: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453
Query: 139 C--QETVRLQPRI-----DQRTAISPKDAFETRQDLNEEEAAQVHGV-KDP--APASTQS 188
++T ++ ++ + S +++ R+ L AAQV + K P PAST
Sbjct: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
Query: 189 V--LADGTDSADP------SPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
+ L G P +P + G+ E DS S +S DG+ P
Sbjct: 514 MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS-------DGEVPTAVAP 566
Query: 241 CSIFSQSQRFNLDPESAPS--PP 261
S P S+P+ PP
Sbjct: 567 AQEKSLGNILQAKPTSSPAKGPP 589
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 35.0 bits (79), Expect = 0.15
Identities = 62/263 (23%), Positives = 106/263 (40%), Gaps = 41/263 (15%)
Query: 31 EDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRPSMGNFKSR 90
E+ ++ SS +++E P A AL++ A S + Q + +S + + +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKA--SGKTSQVGAASAPAKESPRKGAAPAPPGK 393
Query: 91 KPKSIFKAESGRSHGESQETEHVVSSQSEC-----------QVRAGT-PAHESPQNNAFK 138
++ KA++G+ +SQ + S+ E QVRA + PA ESP+ A
Sbjct: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453
Query: 139 C--QETVRLQPRI-----DQRTAISPKDAFETRQDLNEEEAAQVHGV-KDP--APASTQS 188
++T ++ ++ + S +++ R+ L AAQV + K P PAST
Sbjct: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
Query: 189 V--LADGTDSADP------SPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPR 240
+ L G P +P + G+ E DS S +S DG+ P
Sbjct: 514 MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS-------DGEVPTAVAP 566
Query: 241 CSIFSQSQRFNLDPESAPS--PP 261
S P S+P+ PP
Sbjct: 567 AQEKSLGNILQAKPTSSPAKGPP 589
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 34.7 bits (78), Expect = 0.20
Identities = 62/262 (23%), Positives = 95/262 (36%), Gaps = 58/262 (22%)
Query: 98 AESGRSHGESQETEHVVS---SQSECQVRAGTPAHESPQN---NAFKCQETVRLQPRIDQ 151
+ SG S+ SQ H S S +VR+ + + SP NA K E D+
Sbjct: 649 SSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPE--------DK 700
Query: 152 RTAISP-KDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLAD--GTDSADPSPVHKDGQN 208
+ P K A E +E V V+ P + S ++ GT + V ++G +
Sbjct: 701 KEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGAD 760
Query: 209 EADSAPEDLHSVGTSRL-----------LYHITDGDNPLLSPR---CSIFSQSQRFNLDP 254
E+ S PED + + L + H P ++P I Q+Q +
Sbjct: 761 ESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTL 820
Query: 255 ESAPSPPSTQQFMMPR-------------SSSRCSCGDGKEPQTITQ------------- 288
+ S S F+ PR S SC DG P+ I Q
Sbjct: 821 QKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSC-DGMRPEAIRQDPTRKGSVVNVNP 879
Query: 289 LTKHIQSLKRKIRKFEEKFEQE 310
QS +IRK++++F E
Sbjct: 880 TNTRPQSDTPEIRKYKKRFNSE 901
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 34.7 bits (78), Expect = 0.20
Identities = 62/262 (23%), Positives = 95/262 (36%), Gaps = 58/262 (22%)
Query: 98 AESGRSHGESQETEHVVS---SQSECQVRAGTPAHESPQN---NAFKCQETVRLQPRIDQ 151
+ SG S+ SQ H S S +VR+ + + SP NA K E D+
Sbjct: 595 SSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPE--------DK 646
Query: 152 RTAISP-KDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLAD--GTDSADPSPVHKDGQN 208
+ P K A E +E V V+ P + S ++ GT + V ++G +
Sbjct: 647 KEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGAD 706
Query: 209 EADSAPEDLHSVGTSRL-----------LYHITDGDNPLLSPR---CSIFSQSQRFNLDP 254
E+ S PED + + L + H P ++P I Q+Q +
Sbjct: 707 ESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTL 766
Query: 255 ESAPSPPSTQQFMMPR-------------SSSRCSCGDGKEPQTITQ------------- 288
+ S S F+ PR S SC DG P+ I Q
Sbjct: 767 QKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSC-DGMRPEAIRQDPTRKGSVVNVNP 825
Query: 289 LTKHIQSLKRKIRKFEEKFEQE 310
QS +IRK++++F E
Sbjct: 826 TNTRPQSDTPEIRKYKKRFNSE 847
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 34.7 bits (78), Expect = 0.20
Identities = 62/262 (23%), Positives = 95/262 (36%), Gaps = 58/262 (22%)
Query: 98 AESGRSHGESQETEHVVS---SQSECQVRAGTPAHESPQN---NAFKCQETVRLQPRIDQ 151
+ SG S+ SQ H S S +VR+ + + SP NA K E D+
Sbjct: 757 SSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPE--------DK 808
Query: 152 RTAISP-KDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLAD--GTDSADPSPVHKDGQN 208
+ P K A E +E V V+ P + S ++ GT + V ++G +
Sbjct: 809 KEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGAD 868
Query: 209 EADSAPEDLHSVGTSRL-----------LYHITDGDNPLLSPR---CSIFSQSQRFNLDP 254
E+ S PED + + L + H P ++P I Q+Q +
Sbjct: 869 ESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTL 928
Query: 255 ESAPSPPSTQQFMMPR-------------SSSRCSCGDGKEPQTITQ------------- 288
+ S S F+ PR S SC DG P+ I Q
Sbjct: 929 QKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSC-DGMRPEAIRQDPTRKGSVVNVNP 987
Query: 289 LTKHIQSLKRKIRKFEEKFEQE 310
QS +IRK++++F E
Sbjct: 988 TNTRPQSDTPEIRKYKKRFNSE 1009
Score = 33.9 bits (76), Expect = 0.34
Identities = 66/289 (22%), Positives = 112/289 (38%), Gaps = 52/289 (17%)
Query: 179 KDPAPASTQSVLADGTDSAD--PSPVHKD-GQNEADSAPEDLHSVGTSRLLYHITDGDNP 235
+DP P S VL+ +DS P P K ++++D P + TSR +P
Sbjct: 659 QDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSR---------SP 709
Query: 236 LLSPRCSIFSQSQRFNLDPESAPSPPSTQ--------QFMMPRSSSRCSCG---DGKEPQ 284
+LS R S S + N S S + + ++PR S S G G +P
Sbjct: 710 VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG 769
Query: 285 TI--TQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQD--KNLIKPL-----YDRYRIIKQ 335
+ +Q + R K E Q + V K + K + +PL D + K+
Sbjct: 770 SHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKE 829
Query: 336 ILSTPSLIP--------TIQEE----EDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNE 383
+ + + P + EE ++ D+D Q S + P + E
Sbjct: 830 LRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGE 889
Query: 384 TEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRK 432
TE V+ ++ + E +P +M+ E T+ V R+T++ L+K
Sbjct: 890 TESVKTMIVHDDVESEP---AMTPSKEGTLIV-----RQTQSASSTLQK 930
>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
Length = 1711
Score = 34.7 bits (78), Expect = 0.20
Identities = 34/161 (21%), Positives = 69/161 (42%), Gaps = 23/161 (14%)
Query: 286 ITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPT 345
+ + T+ +QSL R ++ ++ ++ + L + D R+ +Q+ T +L
Sbjct: 461 LQESTQTVQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALR-- 518
Query: 346 IQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSM 405
QE EDS + R +G ++ H E E + L + + +K A +
Sbjct: 519 -QEREDSTQ-RLRGLEK-------------QHRVVRQEKEELHKQLVEASERLKSQAKEL 563
Query: 406 SNLHEATMPVLLD------HLRETRADKKRLRKALREFEEQ 440
+ H+ L + + E RA K+++ + LR+ EE+
Sbjct: 564 KDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEE 604
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 33.9 bits (76), Expect = 0.34
Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 16/125 (12%)
Query: 284 QTITQLTKHIQSLKRKIRK-FEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSL 342
Q + + IQ+LK +I + ++ E E + +K KP+Y I ++ L
Sbjct: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVY-----IPEVELNHKL 333
Query: 343 IPTIQEEE-DSDEDRPQ--GSQQ---PSLADPASHLPVGDHLTYSNETEPVRALLPDEKK 396
I I + D + Q G Q PS DP H P H T PV+ + +EKK
Sbjct: 334 IKGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTH----KSTRPVKKVSKEEKK 389
Query: 397 EVKPP 401
KPP
Sbjct: 390 SKKPP 394
>gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens]
Length = 553
Score = 33.5 bits (75), Expect = 0.45
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 17/95 (17%)
Query: 333 IKQILSTPSLIPTIQEEEDSDED---------RPQGSQQ---PSLADPASHLPVGDHLT- 379
+K + TP++ P ++E+D D+D RP+ ++ S+ +P P D T
Sbjct: 161 VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATS 220
Query: 380 ----YSNETEPVRALLPDEKKEVKPPALSMSNLHE 410
N T P AL + +K+ K P +S + E
Sbjct: 221 PISPTENNTTPPDALTRNTEKQKKKPKMSDEEILE 255
>gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens]
Length = 545
Score = 33.5 bits (75), Expect = 0.45
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 17/95 (17%)
Query: 333 IKQILSTPSLIPTIQEEEDSDED---------RPQGSQQ---PSLADPASHLPVGDHLT- 379
+K + TP++ P ++E+D D+D RP+ ++ S+ +P P D T
Sbjct: 161 VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATS 220
Query: 380 ----YSNETEPVRALLPDEKKEVKPPALSMSNLHE 410
N T P AL + +K+ K P +S + E
Sbjct: 221 PISPTENNTTPPDALTRNTEKQKKKPKMSDEEILE 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,712,059
Number of Sequences: 37866
Number of extensions: 1055869
Number of successful extensions: 4238
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 134
Number of HSP's that attempted gapping in prelim test: 4097
Number of HSP's gapped (non-prelim): 242
length of query: 487
length of database: 18,247,518
effective HSP length: 106
effective length of query: 381
effective length of database: 14,233,722
effective search space: 5423048082
effective search space used: 5423048082
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.