Guide to the Human Genome
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Name: PAK1 Sequence: fasta or formatted (553aa) NCBI GI: 190886457
Description:

p21-activated kinase 1 isoform 1

Referenced in:

Rho and Rac
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [545aa] p21-activated kinase 1 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         33           2
 C cysteine            1.4          8           2
 D aspartate           6.3         35           6
 E glutamate           8.0         44           2
 F phenylalanine       2.7         15           1
 G glycine             4.9         27           2
 H histidine           1.3          7           1
 I isoleucine          5.4         30           2
 K lysine              8.0         44           4
 L leucine             7.4         41           2
 M methionine          3.3         18           1
 N asparagine          5.4         30           2
 P proline             8.0         44           3
 Q glutamine           4.2         23           3
 R arginine            4.0         22           1
 S serine              7.4         41           2
 T threonine           6.9         38           2
 V valine              6.3         35           2
 W tryptophan          0.7          4           1
 Y tyrosine            2.5         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   p21-activated kinase 1 isoform 1 
PAK1                  0.932   p21-activated kinase 1 isoform 2 
PAK3                  0.739   p21-activated kinase 3 isoform a 
PAK3                  0.739   p21-activated kinase 3 isoform a 
PAK3                  0.739   p21-activated kinase 3 isoform a 
PAK3                  0.729   p21-activated kinase 3 isoform d 
PAK3                  0.728   p21-activated kinase 3 isoform c 
PAK3                  0.722   p21-activated kinase 3 isoform b 
PAK2                  0.677   p21-activated kinase 2 
PAK4                  0.284   p21-activated kinase 4 isoform 2 
PAK4                  0.284   p21-activated kinase 4 isoform 2 
PAK4                  0.252   p21-activated kinase 4 isoform 1 
PAK4                  0.252   p21-activated kinase 4 isoform 1 
PAK4                  0.252   p21-activated kinase 4 isoform 1 
PAK7                  0.251   p21-activated kinase 7 
PAK7                  0.251   p21-activated kinase 7 
PAK6                  0.243   p21-activated kinase 6 
PAK6                  0.243   p21-activated kinase 6 
PAK6                  0.243   p21-activated kinase 6 
STK4                  0.186   serine/threonine kinase 4 
MST4                  0.185   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK24                 0.183   serine/threonine kinase 24 isoform b 
STK24                 0.183   serine/threonine kinase 24 isoform a 
STK25                 0.183   serine/threonine kinase 25 
STK3                  0.182   serine/threonine kinase 3 
MAP4K2                0.164   mitogen-activated protein kinase kinase kinase kinas...
MAP4K3                0.162   mitogen-activated protein kinase kinase kinase kinas...
SLK                   0.161   serine/threonine kinase 2 
MYO3A                 0.160   myosin IIIA 
MAP4K5                0.160   mitogen-activated protein kinase kinase kinase kinas...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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