Guide to the Human Genome
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Search of human proteins with 50843820

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50843820 sickle tail isoform 1 [Homo sapiens]
         (1943 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50843820 sickle tail isoform 1 [Homo sapiens]                     3856   0.0  
gi|148612857 sickle tail isoform 3 [Homo sapiens]                    2181   0.0  
gi|148612813 sickle tail isoform 2 [Homo sapiens]                    2101   0.0  
gi|115334682 SNAP25-interacting protein [Homo sapiens]                649   0.0  
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    64   1e-09
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    64   2e-09
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    63   2e-09
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    63   2e-09
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    63   2e-09
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    62   4e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        59   4e-08
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             59   5e-08
gi|41281612 zinc finger protein 828 [Homo sapiens]                     59   6e-08
gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa...    58   8e-08
gi|239742580 PREDICTED: similar to Putative POM121-like protein ...    55   9e-07
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    55   9e-07
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    55   9e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    54   1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         53   3e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          52   4e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          52   4e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   52   6e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   52   6e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   52   6e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    52   6e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    52   6e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   7e-06
gi|55741677 SET domain containing 1A [Homo sapiens]                    51   1e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     51   1e-05
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    51   1e-05

>gi|50843820 sickle tail isoform 1 [Homo sapiens]
          Length = 1943

 Score = 3856 bits (9999), Expect = 0.0
 Identities = 1943/1943 (100%), Positives = 1943/1943 (100%)

Query: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60
            MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS
Sbjct: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60

Query: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120
            RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR
Sbjct: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120

Query: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180
            SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK
Sbjct: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180

Query: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240
            ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES
Sbjct: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240

Query: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300
            RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP
Sbjct: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300

Query: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360
            GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI
Sbjct: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360

Query: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420
            SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH
Sbjct: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420

Query: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480
            IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD
Sbjct: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480

Query: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540
            LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL
Sbjct: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540

Query: 541  MEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMK 600
            MEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMK
Sbjct: 541  MEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMK 600

Query: 601  TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL 660
            TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL
Sbjct: 601  TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL 660

Query: 661  QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK 720
            QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK
Sbjct: 661  QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK 720

Query: 721  IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR 780
            IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR
Sbjct: 721  IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR 780

Query: 781  AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM 840
            AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM
Sbjct: 781  AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM 840

Query: 841  EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS 900
            EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS
Sbjct: 841  EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS 900

Query: 901  VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN 960
            VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN
Sbjct: 901  VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN 960

Query: 961  RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP 1020
            RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP
Sbjct: 961  RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP 1020

Query: 1021 VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT 1080
            VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT
Sbjct: 1021 VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT 1080

Query: 1081 AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAF 1140
            AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAF
Sbjct: 1081 AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAF 1140

Query: 1141 QKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQM 1200
            QKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQM
Sbjct: 1141 QKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQM 1200

Query: 1201 EFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQ 1260
            EFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQ
Sbjct: 1201 EFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQ 1260

Query: 1261 ETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVS 1320
            ETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVS
Sbjct: 1261 ETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVS 1320

Query: 1321 SHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAAT 1380
            SHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAAT
Sbjct: 1321 SHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAAT 1380

Query: 1381 DNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDK 1440
            DNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDK
Sbjct: 1381 DNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDK 1440

Query: 1441 KPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQ 1500
            KPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQ
Sbjct: 1441 KPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQ 1500

Query: 1501 MSHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGED 1560
            MSHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGED
Sbjct: 1501 MSHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGED 1560

Query: 1561 ATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEA 1620
            ATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEA
Sbjct: 1561 ATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEA 1620

Query: 1621 KRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTI 1680
            KRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTI
Sbjct: 1621 KRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTI 1680

Query: 1681 SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSS 1740
            SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSS
Sbjct: 1681 SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSS 1740

Query: 1741 GAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPAS 1800
            GAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPAS
Sbjct: 1741 GAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPAS 1800

Query: 1801 KIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNG 1860
            KIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNG
Sbjct: 1801 KIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNG 1860

Query: 1861 SLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPS 1920
            SLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPS
Sbjct: 1861 SLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPS 1920

Query: 1921 LTSYKAQNGSSSKATPSTAKETS 1943
            LTSYKAQNGSSSKATPSTAKETS
Sbjct: 1921 LTSYKAQNGSSSKATPSTAKETS 1943


>gi|148612857 sickle tail isoform 3 [Homo sapiens]
          Length = 1309

 Score = 2181 bits (5651), Expect = 0.0
 Identities = 1109/1170 (94%), Positives = 1114/1170 (95%), Gaps = 38/1170 (3%)

Query: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60
            MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS
Sbjct: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60

Query: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120
            RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR
Sbjct: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120

Query: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180
            SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK
Sbjct: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180

Query: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240
            ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES
Sbjct: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240

Query: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300
            RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP
Sbjct: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300

Query: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360
            GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI
Sbjct: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360

Query: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420
            SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH
Sbjct: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420

Query: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480
            IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD
Sbjct: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480

Query: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540
            LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL
Sbjct: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540

Query: 541  MEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMK 600
            MEKQVFAYSTATIPKDRET                                   SEKMMK
Sbjct: 541  MEKQVFAYSTATIPKDRET-----------------------------------SEKMMK 565

Query: 601  TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL 660
            TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL
Sbjct: 566  TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL 625

Query: 661  QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK 720
            QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK
Sbjct: 626  QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK 685

Query: 721  IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR 780
            IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR
Sbjct: 686  IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR 745

Query: 781  AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM 840
            AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM
Sbjct: 746  AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM 805

Query: 841  EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS 900
            EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS
Sbjct: 806  EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS 865

Query: 901  VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN 960
            VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN
Sbjct: 866  VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN 925

Query: 961  RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP 1020
            RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP
Sbjct: 926  RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP 985

Query: 1021 VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT 1080
            VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT
Sbjct: 986  VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT 1045

Query: 1081 AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAF 1140
            AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQ  
Sbjct: 1046 AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGS 1105

Query: 1141 Q---KCSFMDVNSNSHAEPSRADSHVKDTR 1167
                + S M V  ++   P   D   K ++
Sbjct: 1106 SGAPQTSRMPVPMSAKNRPGTLDKPGKQSK 1135



 Score =  414 bits (1065), Expect = e-115
 Identities = 220/275 (80%), Positives = 226/275 (82%), Gaps = 19/275 (6%)

Query: 1688 LVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTAL---EPPTSIPSASR-------- 1736
            +V T    N  + ASS         R    P E P +     PP    S+S+        
Sbjct: 1035 VVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEE 1094

Query: 1737 --------KGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1788
                    +GSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG
Sbjct: 1095 GDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1154

Query: 1789 DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA 1848
            DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA
Sbjct: 1155 DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA 1214

Query: 1849 HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ 1908
            HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ
Sbjct: 1215 HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ 1274

Query: 1909 GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1943
            GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS
Sbjct: 1275 GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1309


>gi|148612813 sickle tail isoform 2 [Homo sapiens]
          Length = 1264

 Score = 2101 bits (5443), Expect = 0.0
 Identities = 1064/1090 (97%), Positives = 1069/1090 (98%), Gaps = 3/1090 (0%)

Query: 81   MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL 140
            MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL
Sbjct: 1    MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL 60

Query: 141  SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM 200
            SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM
Sbjct: 61   SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM 120

Query: 201  PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK 260
            PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK
Sbjct: 121  PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK 180

Query: 261  VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP 320
            VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP
Sbjct: 181  VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP 240

Query: 321  HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS 380
            HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS
Sbjct: 241  HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS 300

Query: 381  GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM 440
            GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM
Sbjct: 301  GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM 360

Query: 441  QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ 500
            QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ
Sbjct: 361  QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ 420

Query: 501  PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETR 560
            PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETR
Sbjct: 421  PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETR 480

Query: 561  ERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTPHVSGGK 620
            ERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTPHVSGGK
Sbjct: 481  ERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTPHVSGGK 540

Query: 621  MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK 680
            MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK
Sbjct: 541  MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK 600

Query: 681  AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST 740
            AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST
Sbjct: 601  AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST 660

Query: 741  AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL 800
            AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL
Sbjct: 661  AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL 720

Query: 801  DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG 860
            DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG
Sbjct: 721  DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG 780

Query: 861  QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP 920
            QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP
Sbjct: 781  QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP 840

Query: 921  QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD 980
            QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD
Sbjct: 841  QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD 900

Query: 981  HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL 1040
            HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL
Sbjct: 901  HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL 960

Query: 1041 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 1100
            GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP
Sbjct: 961  GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 1020

Query: 1101 AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQ---KCSFMDVNSNSHAEPS 1157
            AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQ      + S M V  ++   P 
Sbjct: 1021 AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1080

Query: 1158 RADSHVKDTR 1167
              D   K ++
Sbjct: 1081 TLDKPGKQSK 1090



 Score =  414 bits (1065), Expect = e-115
 Identities = 220/275 (80%), Positives = 226/275 (82%), Gaps = 19/275 (6%)

Query: 1688 LVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTAL---EPPTSIPSASR-------- 1736
            +V T    N  + ASS         R    P E P +     PP    S+S+        
Sbjct: 990  VVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEE 1049

Query: 1737 --------KGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1788
                    +GSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG
Sbjct: 1050 GDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1109

Query: 1789 DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA 1848
            DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA
Sbjct: 1110 DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA 1169

Query: 1849 HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ 1908
            HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ
Sbjct: 1170 HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ 1229

Query: 1909 GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1943
            GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS
Sbjct: 1230 GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1264


>gi|115334682 SNAP25-interacting protein [Homo sapiens]
          Length = 1183

 Score =  649 bits (1674), Expect = 0.0
 Identities = 453/1172 (38%), Positives = 642/1172 (54%), Gaps = 142/1172 (12%)

Query: 23   QEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNI------PRRHTLGGPRSSK 76
            Q+  + +  + S +DAE  R    L  G   GS  +   N+       RRHT+   +S +
Sbjct: 7    QDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVIAAQSLE 66

Query: 77   EILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQ-------TRSPKLSHSPQ 129
             + G+Q ++ DRKR+AF++HLK KYP HA A+ G Q+R+R+Q       TRS + +   Q
Sbjct: 67   ALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSRHTQGAQ 126

Query: 130  PPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYL 189
            P  L D    LS  SA+SLE MSE + P  FSR +R R SLP+ RS +QTK RS GVL+L
Sbjct: 127  P-GLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFL 185

Query: 190  QYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELND 249
            Q+G+ET+++ + +E++S DT+ AL    FPQ+LTM ML+SP+ AI IKDE+RNV+YEL D
Sbjct: 186  QFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELED 245

Query: 250  VRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHA 309
            VR+IQDRS++K+Y K+P +A        NGD+R  RE+VYA  +     R  + +  PH 
Sbjct: 246  VRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLR--REMVYASRESSPTRRLNNLSPAPHL 303

Query: 310  IPNSPPSTPVPHSMP-------PSPSRIPYGGTRSMVVPGNATI-PRDRISSLPVSRPIS 361
               SPP   +P  +P       PS SR+ Y G R     G+      +R+   P ++ +S
Sbjct: 304  ASGSPPPG-LPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVS 362

Query: 362  PSPSAILERRDVKPDEDMSGK--NIAMYRNEGFYADPY-LYHEGRMSIASSHGGHPLDVP 418
            PSPSAILERRDVKPDED++ K   + + + EG YADPY L HEGR+S+A++  G P   P
Sbjct: 363  PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAA-AGDPFAYP 421

Query: 419  DHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRV 478
                 Y R ++RS S Y   ++Q+++  E SLY+      P  +    G + PP+SP ++
Sbjct: 422  GAGGLYKRGSVRSLSTYSAAALQSDL--EDSLYKAAGGGGP-LYGDGYGFRLPPSSPQKL 478

Query: 479  SDLRMIDMHAHYNAHGPPHTMQ---PDRASPSRQAFKKEPGTL-VYIEKP----RSAAGL 530
            +D+      A      PPH+     P R SP RQ+F+K+ G+  V+ E P    RSA   
Sbjct: 479  ADVA-----APPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSA 533

Query: 531  SSL----VDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKG-- 584
            S+      +L P   E+ +  +      KD ETRERM+AMEKQIASLTGLVQSAL +G  
Sbjct: 534  STAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQIASLTGLVQSALLRGSE 593

Query: 585  PITSYSK-DASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIH 643
            P T   K + S+     +    +   S+G   VSG    SA  S+ P  QP  V    + 
Sbjct: 594  PETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSA--SSTPAGQPTAVSRLQMQ 651

Query: 644  MSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQ 703
            + L  ++ S ++LR QLQQ+R+LQLQNQE +RA++K+ E E+S +V E  +R EDP+QRQ
Sbjct: 652  LHLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQ 711

Query: 704  RVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGE 763
            R LVE+ER +YL++EE I ++L +LE  VE +++D +   RLV   ++E+ A +L+Q+GE
Sbjct: 712  RTLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGE 771

Query: 764  AVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTD 823
             +  LK  FP LQ+KMR +LR+EVEAV+FLKEEP +LD LLKR R            VTD
Sbjct: 772  TLTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRG-----------VTD 820

Query: 824  GLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMM 883
             L      AQ  + +          L SQ     T+   F+ +        E+ P S   
Sbjct: 821  TL------AQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKS-----VDFEMPPPS--- 866

Query: 884  VRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGS 943
                                  P  NL H  S PA     T              P  G+
Sbjct: 867  ----------------------PPLNL-HELSGPAEGASLT--------------PKGGN 889

Query: 944  AMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIP 1003
              + L      SV   ++AVS+E AE+ WEEKR  L  Y+ K+  +LLEE QA ++K+IP
Sbjct: 890  PTKGLDTPGKRSV---DKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIP 946

Query: 1004 NLEMPPAT--GPLPRGD-----APVDKVELSEDSPNSEQDLEKL-------GGKSPPPPP 1049
            +L+       GP P  D     AP  +       P+  +  ++L          S  PPP
Sbjct: 947  DLDCASKAHPGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPP 1006

Query: 1050 PPPRRSYLPGSGLTTTRSGDVVYTGRKEN-ITAKASSEDAG-PSPQTRATKYPAEEPASA 1107
            PPPRRS+    GLTTTR+G+VV T +K++    KA SE+     PQ +  +  +E    A
Sbjct: 1007 PPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPA 1066

Query: 1108 WTPSPPPVTTSSSKDEEEEEEEGDKIMAELQA 1139
               S PP+  S+ KDE++E    D+I+AEL++
Sbjct: 1067 ---STPPIMASAIKDEDDE----DRIIAELES 1091



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 105/466 (22%), Positives = 166/466 (35%), Gaps = 66/466 (14%)

Query: 1514 GQQVETKSQPHSLATETRNP----GGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESP 1569
            GQQ   + QP+  + +TR+     G Q     +  K S+  + + E   E      F S 
Sbjct: 100  GQQDRMREQPNYWSFKTRSSRHTQGAQPGLADQAAKLSYASAESLETMSEAELPLGF-SR 158

Query: 1570 KKKFKFKFPKKQLAALTQAIRTGT---KTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIA 1626
              +F+   P  + A+ T+    G    + G++T +V +  E     TL          IA
Sbjct: 159  MNRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHAL-------IA 211

Query: 1627 RSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPK 1686
               P+     T+   + P+    + I   DE R   Y   D  +   + +     +    
Sbjct: 212  HMFPQKL---TMGMLKSPN----TAILIKDEARNVFYELEDVRDIQDRSIIKIYRKEPLY 264

Query: 1687 ALVDTSCSSNRDSVASSSHIAQEASP-RPL--LVPDEGPTALEPPTSIPSASRKG-SSGA 1742
            A    S  +N D      + ++E+SP R L  L P     +  PP  +PS    G  SG+
Sbjct: 265  AAFPGSHLTNGDLRREMVYASRESSPTRRLNNLSPAPHLASGSPPPGLPSGLPSGLQSGS 324

Query: 1743 PQTSRM-------------PVPMSAKNRPGTLDKPG---KQSKLQDPRQYRQANGSAKKS 1786
            P  SR+             PV  +A+   G     G     S + + R  +     A K+
Sbjct: 325  PSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKA 384

Query: 1787 GGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGP 1846
            GG        L A     L        SL +++GD    P         +   LS  +  
Sbjct: 385  GGMVLVKGEGLYADPYGLLHEGR---LSLAAAAGDPFAYPGAGGLYKRGSVRSLSTYSAA 441

Query: 1847 PAHSA---SLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQN---------GRAPPPLSFS 1894
               S    SL  +   G   +      G G+     P S           G  PPP S  
Sbjct: 442  ALQSDLEDSLYKAAGGGGPLY------GDGYGFRLPPSSPQKLADVAAPPGGPPPPHSPY 495

Query: 1895 SSPPSPASSVSLN-QGAKGTRTI--HTPSLTSYKAQNGSSSKATPS 1937
            S PPS  S V  + +   G+ ++   +P   +  A + S++ A PS
Sbjct: 496  SGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPS 541



 Score = 31.6 bits (70), Expect = 7.9
 Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 21/150 (14%)

Query: 1031 PNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGP 1090
            P+S Q L  +      PPPP     + P SG   +R   V  + RK++ ++   +E  G 
Sbjct: 472  PSSPQKLADVAAPPGGPPPP-----HSPYSG-PPSRGSPVRQSFRKDSGSSSVFAESPGG 525

Query: 1091 SPQTRATKYPAEEPASAWTPSP---------PPVTTSSSKDEEEEEEEGDKIMAELQAFQ 1141
              ++  +   A  P S   P P         PPV    + +  E  E  +K +A L    
Sbjct: 526  KTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDT-ETRERMEAMEKQIASLTGLV 584

Query: 1142 KCSFMDVNSNSHAEPSRADSHVKDTRSGAT 1171
            + + +       +EP      ++ +   AT
Sbjct: 585  QSALL-----RGSEPETPSEKIEGSNGAAT 609


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 150/826 (18%), Positives = 283/826 (34%), Gaps = 113/826 (13%)

Query: 1193 EYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMS-- 1250
            E     ++  QK      R S P     G   +I   S T  ++     +ENS SN    
Sbjct: 73   ELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENS-SNQGKD 131

Query: 1251 -LLRDSRNYS---QETVPKASFGFSGISPL-EDEINKGSKISGLQYSIPDTENQTLNYGK 1305
             ++R+ R+       T  K S G   I+P  + +IN     +G + ++    ++T   G+
Sbjct: 132  PMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTG-KSTVTRKSDKT---GR 187

Query: 1306 TKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNED 1365
              E      DK   SSH   T +S H+      +  +T F + +    +  +      E+
Sbjct: 188  PLEKSMSTLDKTSTSSHK--TTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEE 245

Query: 1366 GESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQK----GEDIQTVNIDARKE 1421
             E +  S T    A+D +    T+   + +S+ E+   +++     G      N  +  E
Sbjct: 246  SEKTEDSRT--TVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE 303

Query: 1422 MTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTI-FEECDEELERMMMEEK- 1479
             T  +E T NE+  +     P      EP++ R      +T  F     E   M   E  
Sbjct: 304  PTENRERTANENTTL----SPA-----EPIENRERTANENTAPFPAGPTENREMTANENT 354

Query: 1480 -IEEEEEEENGDSVVQNNNT----------SQMSHKKVAPGNLRTGQQVETKSQPHSLAT 1528
             +   E  E+G+     N T           + +++   P      +  E     +   T
Sbjct: 355  TLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTT 414

Query: 1529 ETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESP------KKKFKFKFPKKQL 1582
             +     +   RT L   +   SP    +  + T ++  +P      + +      K  L
Sbjct: 415  SSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTL 474

Query: 1583 AALTQAIRTGTKTGKKTL-----------QVVVYEEEEEDGTLKQHKEAKRFEIARSQPE 1631
            + +       T   +KT            +     E+    + +  +  +R  +A     
Sbjct: 475  SPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTT 534

Query: 1632 DTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDT 1691
             +P      +E+ + E T+P     E  +N  RT  + E+T      T S   P      
Sbjct: 535  PSPAEPTENRERTANEKTTPSPA--EPTENGDRTPLANEKT------TPSLAEPTENGQR 586

Query: 1692 SCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVP 1751
            +  +N  + +SS+   +     PL   +  P+  EP  +    + + ++ +P        
Sbjct: 587  TPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRE 646

Query: 1752 MSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGK 1811
            M+A  +              +P + R+   + K +     P  P+    + P  +  +  
Sbjct: 647  MTANEKTTLFPA--------EPTENRERTANEKTTSS---PAEPTENGQRTPFANEKTTS 695

Query: 1812 SSSLPSSSGDSSNLPNP-----PATKPSIASNPLSPQTGP-PAHSASLIPSVSNGSLKFQ 1865
            SS+ P+  G+ + L N      PA          + +T P PA         +N +    
Sbjct: 696  SSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPS 755

Query: 1866 SLTHTGKGHHL---------SFSPQSQNGRAPP--------------------PLSFSSS 1896
                T  G            S +  ++NG+  P                    PL+  ++
Sbjct: 756  PAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENT 815

Query: 1897 PPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKET 1942
              SPA      +     +T   P+  +   ++ ++ K TP  A+ T
Sbjct: 816  TSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPT 861



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 143/798 (17%), Positives = 273/798 (34%), Gaps = 78/798 (9%)

Query: 851  SQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNL 910
            + E+   +  +P  +      A  +    S     H + +P+  + +  S A   P +N 
Sbjct: 487  ANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA--EPTENR 544

Query: 911  PHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEK 970
               A+    P  A  T    + P + +      A  +   E        N   +   AE 
Sbjct: 545  ERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPT---ENGQRTPFANEKTTSSSAEP 601

Query: 971  KWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPV-DKVEL--S 1027
               E+R  L + N         E   N  ++      P   GP    +    +K  L  +
Sbjct: 602  TEHEERTPLANENTTPSPA---EPTENRERTANENTTPSPAGPTENREMTANEKTTLFPA 658

Query: 1028 EDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRK-----ENITAK 1082
            E + N E+   +    SP  P    +R+       TT+ S +    G +     EN T  
Sbjct: 659  EPTENRERTANEKTTSSPAEPTENGQRTPFANEK-TTSSSAEPTEHGERTPLANENTTLS 717

Query: 1083 AS--SEDAGPSPQTRATKYPAEEPASA-------WTPSPPPVTTSSSKDEEEEEEEGDKI 1133
             +  +E+   +   + T +PAE   +         TPSP   T +  +     E+    +
Sbjct: 718  PAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSL 777

Query: 1134 MAELQAFQKCSFM-DVNSNSHAEPSRADSHVKDTRSGATVPPKEK-KNLE-FFHEDVRKS 1190
                +  ++  F  +  ++S AEP+             T  P E  +N E   +E   + 
Sbjct: 778  AEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQF 837

Query: 1191 DVE-YENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTS-EYKTEIIMKENSISN 1248
              E  EN      +K T     P++  +W      ++S A  T  E  T +  ++ ++S 
Sbjct: 838  PAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSP 897

Query: 1249 MSLLRDSRNY---SQETVPKAS--FGFSGISPLEDEINKGSKISGLQY--------SIPD 1295
                 +       +++T P ++        +PL +EI   S+    ++        + P 
Sbjct: 898  AEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPS 957

Query: 1296 TENQTLNYGKTKEMEK------------QNTDKCHVSSHTRLTESSVHDFKTEDQEVITT 1343
                T  +G+T   E             + T   + ++ T  TES+ H  +T +++   +
Sbjct: 958  PAKPT-EHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPS 1016

Query: 1344 DFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDI 1403
                    P E      + NE    S + PTE    T +     T + V+    GE   +
Sbjct: 1017 P-----AEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTL 1071

Query: 1404 VSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTI 1463
             ++K      + +          + T   + +     KP     +      S   ++++ 
Sbjct: 1072 ANEK------ITLSPEGPTEHGAKTTSANEKITPSLAKPT----EHGERTTSPNDKITSS 1121

Query: 1464 FEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQP 1523
              E  E  +R      I     E      +++   + ++H+K+     ++ +  E  +  
Sbjct: 1122 AAESTEHRDRATSANVITPAPAEP-----IKHAKRTTLAHEKMTQVTEKSTEHPEKTTST 1176

Query: 1524 HSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLA 1583
                T T         +T   K  +   P    +    T    E+ K   K     ++ A
Sbjct: 1177 TEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTA 1236

Query: 1584 ALTQAIRTGTK-TGKKTL 1600
            A+T+ I+   K TG K+L
Sbjct: 1237 AVTKTIKPSVKVTGDKSL 1254


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 147/826 (17%), Positives = 283/826 (34%), Gaps = 113/826 (13%)

Query: 1193 EYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMS-- 1250
            E     ++  QK      R S P     G   +I   S T  ++     +ENS SN    
Sbjct: 135  ELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENS-SNQGKD 193

Query: 1251 -LLRDSRNYS---QETVPKASFGFSGISPL-EDEINKGSKISGLQYSIPDTENQTLNYGK 1305
             ++R+ R+       T  K S G   I+P  + +IN     +G + ++    ++T   G+
Sbjct: 194  PMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTG-KSTVTRKSDKT---GR 249

Query: 1306 TKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNED 1365
              E      DK   SSH   T +S H+      +  +T F + +    +  +      E+
Sbjct: 250  PLEKSMSTLDKTSTSSHK--TTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEE 307

Query: 1366 GESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQK----GEDIQTVNIDARKE 1421
             E +  S T    A+D +    T+   + +S+ E+   +++     G      N  +  E
Sbjct: 308  SEKTEDSRT--TVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE 365

Query: 1422 MTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTI-FEECDEELERMMMEEK- 1479
             T  +E T NE+  +     P      EP + R      +T  F     E   M   E  
Sbjct: 366  PTENRERTANENTTL----SPA-----EPTENRERTANENTAPFPAGPTENREMTANENT 416

Query: 1480 -IEEEEEEENGDSVVQNNNT----------SQMSHKKVAPGNLRTGQQVETKSQPHSLAT 1528
             +   E  E+G+     N T           + +++   P      +  E     +   T
Sbjct: 417  TLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTT 476

Query: 1529 ETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESP------KKKFKFKFPKKQL 1582
             +     +   RT L   +   SP    +  + T ++  +P      + +      K  L
Sbjct: 477  SSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTL 536

Query: 1583 AALTQAIRTGTKTGKKTL-----------QVVVYEEEEEDGTLKQHKEAKRFEIARSQPE 1631
            + +       T   +KT            +     E+    + +  +  +R  +A     
Sbjct: 537  SPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTT 596

Query: 1632 DTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDT 1691
             +P      +E+ + E T+P     E  +N  RT  + E+T      T S   P      
Sbjct: 597  PSPAEPTENRERTANEKTTPSPA--EPTENGDRTPLANEKT------TPSLAEPTENGQR 648

Query: 1692 SCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVP 1751
            +  +N  + +SS+   +     PL   +  P+  EP  +    + + ++ +P        
Sbjct: 649  TPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRE 708

Query: 1752 MSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGK 1811
            M+A  +              +P + R+   + K +     P  P+    + P  +  +  
Sbjct: 709  MTANEKTTLFPA--------EPTENRERTANEKTTSS---PAEPTENGQRTPFANEKTTS 757

Query: 1812 SSSLPSSSGDSSNLPN---------PPATKPSIASNPLSPQTGPPAHSA------SLIPS 1856
            SS+ P+  G+ + L N         P   +   A+   +P    P  +       +  PS
Sbjct: 758  SSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPS 817

Query: 1857 VSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPP--------------------PLSFSSS 1896
             +  +          +    S +  ++NG+  P                    PL+  ++
Sbjct: 818  PAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENT 877

Query: 1897 PPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKET 1942
              SPA      +     +T   P+  +   ++ ++ K TP  A+ T
Sbjct: 878  TSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPT 923


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 205/1060 (19%), Positives = 369/1060 (34%), Gaps = 133/1060 (12%)

Query: 942  GSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKS 1001
            G     L +EE  S   +      EK+E   E+  ++ +     E E+  ++ + ++ K 
Sbjct: 880  GDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASE-EQPSQDGKPDLPKR 938

Query: 1002 IPNLEMPPATGPLPRGDAPVDKVELSEDSPN-----SEQDLEKLGG---KSPPPPPPPPR 1053
              +  + P  G L +    + K  L+E S       SE D   L G    S     P   
Sbjct: 939  RLSEGVEPWRGQLKKSPEAL-KCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESP 997

Query: 1054 RSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEP-ASAWTPSP 1112
            RS  P      T      +  R+  +  +     +  +     T    +EP   + +  P
Sbjct: 998  RSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERP 1057

Query: 1113 PPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDV-NSNSHAEPSRADSHVKDTRSGAT 1171
             P    + + +EEEEEE +  +   + F++ S  DV    S ++    D    +    A 
Sbjct: 1058 MPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDAD 1117

Query: 1172 VPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWER--GMENSISDA 1229
              P  K        DV+ S +E +    ++ +K      +   P  W++  G +     +
Sbjct: 1118 DTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKG-KSRKPIHWKKRPGRKPGFKLS 1176

Query: 1230 SRTSEYKTEIIMKENSISNMSLLRDSR-NYSQETV-PKASFGFSGISPLEDEINKGSKIS 1287
                   T+  + E  +S     R  +   S+ETV PK         PL +E  +  +  
Sbjct: 1177 REIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDM------PLPEERKEEEE-- 1228

Query: 1288 GLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQ 1347
             +Q    + E        + E+   +      S  T   E  V +   E++  ++ +  Q
Sbjct: 1229 -MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEE--EEEKPRVSEEQRQ 1285

Query: 1348 VVLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQK 1407
                 +E         ED  + ++   + +A  ++   + +    ++       D+  + 
Sbjct: 1286 SEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEP 1345

Query: 1408 GEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEEC 1467
            G  +Q   +DA  + + R++  D E+  +  ++       ++P    S         E+ 
Sbjct: 1346 G--VQESFLDANMQKS-REKIKDKEETELDSEE-------EQPSHDTSVVSEQMAGSED- 1394

Query: 1468 DEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLA 1527
            D E +    EE IE +EEEE             + H ++   +L T Q V++ +Q  S  
Sbjct: 1395 DHEEDSHTKEELIELKEEEE-------------IPHSEL---DLETVQAVQSLTQEESSE 1438

Query: 1528 TETRNPGGQEMNRT--ELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAAL 1585
             E      +E       L  ++  D        ED    +  SP    +        +  
Sbjct: 1439 HEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQ--------SHP 1490

Query: 1586 TQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPS 1645
            +Q++R+ +      L+    +   E G+L             S P      T    + PS
Sbjct: 1491 SQSVRSVSSPNVPALESGYTQISPEQGSL-------------SAPSMQNMETSPMMDVPS 1537

Query: 1646 IESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISE----------------------- 1682
            +   S      ++  + +  L S+E T +  EN  S                        
Sbjct: 1538 VSDHS-----QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGL 1592

Query: 1683 MSPKALVDTSC--SSNRDSVASSSHIAQEASPRP-----LLVPD----EGPTALEPPTSI 1731
             S  +L  +SC  +    S+ SS  + Q++S +P     +  P     E P + +     
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPP 1652

Query: 1732 PSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFK 1791
            P   ++     PQ    P P   + +P    +P  Q     P   +Q   S       F 
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFT 1712

Query: 1792 PTSPSLPASKIPALSPSSGKSSSLPSSSGD--SSNLPNPPAT-----KPSIASNPLSPQT 1844
            P +P +   +IP  S S+G  S      GD  + +   P AT        + +  + P  
Sbjct: 1713 P-APMI--MEIPE-SGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHA 1768

Query: 1845 GPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV 1904
             P +HS ++    ++ SL    L      H L+ +PQ+Q    PPP   S++    +  +
Sbjct: 1769 MPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMNLTSPLL 1828

Query: 1905 SLNQGAKGTRTIHTPSLTSYKAQNG-----SSSKATPSTA 1939
              N  A      HT  L       G     S S   PS A
Sbjct: 1829 QCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAA 1868


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 205/1060 (19%), Positives = 369/1060 (34%), Gaps = 133/1060 (12%)

Query: 942  GSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKS 1001
            G     L +EE  S   +      EK+E   E+  ++ +     E E+  ++ + ++ K 
Sbjct: 880  GDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASE-EQPSQDGKPDLPKR 938

Query: 1002 IPNLEMPPATGPLPRGDAPVDKVELSEDSPN-----SEQDLEKLGG---KSPPPPPPPPR 1053
              +  + P  G L +    + K  L+E S       SE D   L G    S     P   
Sbjct: 939  RLSEGVEPWRGQLKKSPEAL-KCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESP 997

Query: 1054 RSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEP-ASAWTPSP 1112
            RS  P      T      +  R+  +  +     +  +     T    +EP   + +  P
Sbjct: 998  RSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERP 1057

Query: 1113 PPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDV-NSNSHAEPSRADSHVKDTRSGAT 1171
             P    + + +EEEEEE +  +   + F++ S  DV    S ++    D    +    A 
Sbjct: 1058 MPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDAD 1117

Query: 1172 VPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWER--GMENSISDA 1229
              P  K        DV+ S +E +    ++ +K      +   P  W++  G +     +
Sbjct: 1118 DTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKG-KSRKPIHWKKRPGRKPGFKLS 1176

Query: 1230 SRTSEYKTEIIMKENSISNMSLLRDSR-NYSQETV-PKASFGFSGISPLEDEINKGSKIS 1287
                   T+  + E  +S     R  +   S+ETV PK         PL +E  +  +  
Sbjct: 1177 REIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDM------PLPEERKEEEE-- 1228

Query: 1288 GLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQ 1347
             +Q    + E        + E+   +      S  T   E  V +   E++  ++ +  Q
Sbjct: 1229 -MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEE--EEEKPRVSEEQRQ 1285

Query: 1348 VVLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQK 1407
                 +E         ED  + ++   + +A  ++   + +    ++       D+  + 
Sbjct: 1286 SEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEP 1345

Query: 1408 GEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEEC 1467
            G  +Q   +DA  + + R++  D E+  +  ++       ++P    S         E+ 
Sbjct: 1346 G--VQESFLDANMQKS-REKIKDKEETELDSEE-------EQPSHDTSVVSEQMAGSED- 1394

Query: 1468 DEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLA 1527
            D E +    EE IE +EEEE             + H ++   +L T Q V++ +Q  S  
Sbjct: 1395 DHEEDSHTKEELIELKEEEE-------------IPHSEL---DLETVQAVQSLTQEESSE 1438

Query: 1528 TETRNPGGQEMNRT--ELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAAL 1585
             E      +E       L  ++  D        ED    +  SP    +        +  
Sbjct: 1439 HEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQ--------SHP 1490

Query: 1586 TQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPS 1645
            +Q++R+ +      L+    +   E G+L             S P      T    + PS
Sbjct: 1491 SQSVRSVSSPNVPALESGYTQISPEQGSL-------------SAPSMQNMETSPMMDVPS 1537

Query: 1646 IESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISE----------------------- 1682
            +   S      ++  + +  L S+E T +  EN  S                        
Sbjct: 1538 VSDHS-----QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGL 1592

Query: 1683 MSPKALVDTSC--SSNRDSVASSSHIAQEASPRP-----LLVPD----EGPTALEPPTSI 1731
             S  +L  +SC  +    S+ SS  + Q++S +P     +  P     E P + +     
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPP 1652

Query: 1732 PSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFK 1791
            P   ++     PQ    P P   + +P    +P  Q     P   +Q   S       F 
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFT 1712

Query: 1792 PTSPSLPASKIPALSPSSGKSSSLPSSSGD--SSNLPNPPAT-----KPSIASNPLSPQT 1844
            P +P +   +IP  S S+G  S      GD  + +   P AT        + +  + P  
Sbjct: 1713 P-APMI--MEIPE-SGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHA 1768

Query: 1845 GPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV 1904
             P +HS ++    ++ SL    L      H L+ +PQ+Q    PPP   S++    +  +
Sbjct: 1769 MPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMNLTSPLL 1828

Query: 1905 SLNQGAKGTRTIHTPSLTSYKAQNG-----SSSKATPSTA 1939
              N  A      HT  L       G     S S   PS A
Sbjct: 1829 QCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAA 1868


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 205/1060 (19%), Positives = 369/1060 (34%), Gaps = 133/1060 (12%)

Query: 942  GSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKS 1001
            G     L +EE  S   +      EK+E   E+  ++ +     E E+  ++ + ++ K 
Sbjct: 880  GDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASE-EQPSQDGKPDLPKR 938

Query: 1002 IPNLEMPPATGPLPRGDAPVDKVELSEDSPN-----SEQDLEKLGG---KSPPPPPPPPR 1053
              +  + P  G L +    + K  L+E S       SE D   L G    S     P   
Sbjct: 939  RLSEGVEPWRGQLKKSPEAL-KCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESP 997

Query: 1054 RSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEP-ASAWTPSP 1112
            RS  P      T      +  R+  +  +     +  +     T    +EP   + +  P
Sbjct: 998  RSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERP 1057

Query: 1113 PPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDV-NSNSHAEPSRADSHVKDTRSGAT 1171
             P    + + +EEEEEE +  +   + F++ S  DV    S ++    D    +    A 
Sbjct: 1058 MPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDAD 1117

Query: 1172 VPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWER--GMENSISDA 1229
              P  K        DV+ S +E +    ++ +K      +   P  W++  G +     +
Sbjct: 1118 DTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKG-KSRKPIHWKKRPGRKPGFKLS 1176

Query: 1230 SRTSEYKTEIIMKENSISNMSLLRDSR-NYSQETV-PKASFGFSGISPLEDEINKGSKIS 1287
                   T+  + E  +S     R  +   S+ETV PK         PL +E  +  +  
Sbjct: 1177 REIMPVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDM------PLPEERKEEEE-- 1228

Query: 1288 GLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQ 1347
             +Q    + E        + E+   +      S  T   E  V +   E++  ++ +  Q
Sbjct: 1229 -MQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEE--EEEKPRVSEEQRQ 1285

Query: 1348 VVLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQK 1407
                 +E         ED  + ++   + +A  ++   + +    ++       D+  + 
Sbjct: 1286 SEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEP 1345

Query: 1408 GEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEEC 1467
            G  +Q   +DA  + + R++  D E+  +  ++       ++P    S         E+ 
Sbjct: 1346 G--VQESFLDANMQKS-REKIKDKEETELDSEE-------EQPSHDTSVVSEQMAGSED- 1394

Query: 1468 DEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLA 1527
            D E +    EE IE +EEEE             + H ++   +L T Q V++ +Q  S  
Sbjct: 1395 DHEEDSHTKEELIELKEEEE-------------IPHSEL---DLETVQAVQSLTQEESSE 1438

Query: 1528 TETRNPGGQEMNRT--ELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAAL 1585
             E      +E       L  ++  D        ED    +  SP    +        +  
Sbjct: 1439 HEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQ--------SHP 1490

Query: 1586 TQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPS 1645
            +Q++R+ +      L+    +   E G+L             S P      T    + PS
Sbjct: 1491 SQSVRSVSSPNVPALESGYTQISPEQGSL-------------SAPSMQNMETSPMMDVPS 1537

Query: 1646 IESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISE----------------------- 1682
            +   S      ++  + +  L S+E T +  EN  S                        
Sbjct: 1538 VSDHS-----QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGL 1592

Query: 1683 MSPKALVDTSC--SSNRDSVASSSHIAQEASPRP-----LLVPD----EGPTALEPPTSI 1731
             S  +L  +SC  +    S+ SS  + Q++S +P     +  P     E P + +     
Sbjct: 1593 SSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPP 1652

Query: 1732 PSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFK 1791
            P   ++     PQ    P P   + +P    +P  Q     P   +Q   S       F 
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNNSFT 1712

Query: 1792 PTSPSLPASKIPALSPSSGKSSSLPSSSGD--SSNLPNPPAT-----KPSIASNPLSPQT 1844
            P +P +   +IP  S S+G  S      GD  + +   P AT        + +  + P  
Sbjct: 1713 P-APMI--MEIPE-SGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHA 1768

Query: 1845 GPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV 1904
             P +HS ++    ++ SL    L      H L+ +PQ+Q    PPP   S++    +  +
Sbjct: 1769 MPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMNLTSPLL 1828

Query: 1905 SLNQGAKGTRTIHTPSLTSYKAQNG-----SSSKATPSTA 1939
              N  A      HT  L       G     S S   PS A
Sbjct: 1829 QCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAA 1868


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 673

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 82/340 (24%), Positives = 125/340 (36%), Gaps = 33/340 (9%)

Query: 1625 IARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEM- 1683
            + R+ P  +P   + R     ++ST+ I+RT         T      ++    +T S M 
Sbjct: 247  LIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMR 306

Query: 1684 -----SPKALVDTSCSSNRDSVASSSHIAQEAS-----------PRPLLVPDEGPTALEP 1727
                 SP  ++  +  +  DS AS S     AS            +P      G  +   
Sbjct: 307  MLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRAS 366

Query: 1728 PTSIPS-ASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKS 1786
            PT  PS AS  G S     +  P   S    P T     K  +        + + +   S
Sbjct: 367  PTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDS 426

Query: 1787 GGDFKPTSP-SLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTG 1845
                  T P + P    P  SP+   S + P+ +  +++    P   PS AS   SP T 
Sbjct: 427  TASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTAS----PTGSPSTASPTGSPSTA 482

Query: 1846 PPAHS---ASLIPSVSNGSL----KFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPP 1898
             P  S   ASL  + S  SL       S+T T      +++P + +    P  + +   P
Sbjct: 483  SPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSP 542

Query: 1899 SPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPST 1938
            S A+       A  TRT    SLT+    + +S   TPST
Sbjct: 543  SRAALTRTPSRASLTRTPSRASLTT---PSRASLTRTPST 579



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 80/336 (23%), Positives = 118/336 (35%), Gaps = 25/336 (7%)

Query: 1625 IARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMS 1684
            + R+ P  +P     R     + ST+ +++ D     T RTL     T      T    S
Sbjct: 175  LTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASIT-RTLSRASPT-----GTPPRAS 228

Query: 1685 PKALVDTSCSSNRDSVASSSHIAQEASPRPLLVP------DEGPTALEPPTSIPSASRKG 1738
            P      +  S   S A        ASP  +L        D   +    P+   +AS  G
Sbjct: 229  PTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTG 288

Query: 1739 SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPT-SPSL 1797
            +      S  P   S           G  S+    +    A+ S          T S + 
Sbjct: 289  TPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRAS 348

Query: 1798 PASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLI--- 1854
            P  K    SP+   S + P+ S  +++L    +T     + P +  TG P+ +ASL    
Sbjct: 349  PTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPS-TASLTRKP 407

Query: 1855 PSVS-NGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGT 1913
            P  S  G L   S+T        + +P   +    PP +  +  PS AS       A  T
Sbjct: 408  PRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPT 467

Query: 1914 RTIHTPSLT---SYKAQNGSSSKA----TPSTAKET 1942
             +  T S T   S  +  GS S+A    TPS A  T
Sbjct: 468  GSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLT 503



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 21/232 (9%)

Query: 1725 LEPPTSIPSASRKGSSGAPQTSRM---PVPMSAKNRPGTLDKPGKQSK--LQDPRQYRQA 1779
            + PPT  PS  R   +  P T+ +   P   S    P T    G  S+  L         
Sbjct: 1    MAPPTRTPS--RASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASL 58

Query: 1780 NGSAKKSGGDFKPTSPSLP---ASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATK-PSI 1835
             G+   +     P+  SL    +S +   +PS      +P  +  +  LP     + PS 
Sbjct: 59   KGTTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPST 118

Query: 1836 ASNPLSPQ-----TGPPAHSASLIPSVSNGSL--KFQSLTHTGKGHHLSFSPQSQNGRAP 1888
            AS   SP      T P   S S+ PS +         SLT T     L+ +P + +    
Sbjct: 119  ASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRT 178

Query: 1889 PPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLT---SYKAQNGSSSKATPS 1937
            PP +  +  PS  S   +   A  T+   T S+T   S  +  G+  +A+P+
Sbjct: 179  PPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPT 230


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 177/975 (18%), Positives = 364/975 (37%), Gaps = 106/975 (10%)

Query: 1013 PLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPP------PPRRSYLPGSGLTTTR 1066
            P  +   P  +       P ++        +S   PPP      P R+S+   S     +
Sbjct: 786  PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVK 845

Query: 1067 SGDVVYTG-------RKENITA-KASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTS 1118
            SG     G        ++++T  + S  ++ P P+ ++ + P+    S  +P     +T 
Sbjct: 846  SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS-RTPSRHSCSGSSPPRVKSSTP 904

Query: 1119 SSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKK 1178
              +          K+ A +   Q+      + +S   PSR  S     RS +  P    +
Sbjct: 905  PRQSPSRSSSPQPKVKAIISPRQRSH----SGSSSPSPSRVTSRTTPRRSRSVSPCSNVE 960

Query: 1179 NL---EFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDA-SRTSE 1234
            +     + H      D + +  P+   ++  +G++ P    K +     S+S + S   +
Sbjct: 961  SRLLPRYSHSGSSSPDTKVK--PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ 1018

Query: 1235 YKTEIIMKENSISNMSLLRDSRNYSQETVPKASFGFSGISPLEDEINKGSKISGLQYSIP 1294
             K++  + ++   ++SL    ++    T P  S+   G+S L+        + G   + P
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKS---STPPGESY--FGVSSLQ--------LKGQSQTSP 1065

Query: 1295 DTENQTLNYGKTKEMEKQNTDKCHVSSHTRLT------ESSVHDFKTEDQEVITTDFGQV 1348
            D  + T     + E+ + +++   + S ++ +       SS    +   +  I  D G+ 
Sbjct: 1066 DHRSDT----SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEF 1121

Query: 1349 VLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQKG 1408
               P      +   +     SSS PT ++ +      ++ ++ ++   S E   +  Q+ 
Sbjct: 1122 SASPMLKSGMSPEQSRFQSDSSSYPTVDSNS------LLGQSRLETAESKEKMALPPQE- 1174

Query: 1409 EDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECD 1468
                    DA     PRQ+  D   P    D+    ++F + +      +  +    E  
Sbjct: 1175 --------DATAS-PPRQK--DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETK 1223

Query: 1469 EELERMMM----EEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPH 1524
            E+   +      EE +E  E+ E     + ++ +S++  K+++  N  +  +VE +  P 
Sbjct: 1224 EQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSEL--KEMSTSNFESSPEVEER--PA 1279

Query: 1525 SLATETRNPGGQEMNRTELNKFS------HVDSPNSECKGEDATDDQFESPKKKFKFKFP 1578
               T  ++     +   E+   +      H    + E       ++ F SP + F+   P
Sbjct: 1280 VSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLE-FRNSGP 1338

Query: 1579 KKQLAALTQAIRTGTKTG-KKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENT 1637
                  L   + TG  +  K+ L      + E D +L   +++ R     S  E +P+  
Sbjct: 1339 ------LGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS-GHSSSELSPDAV 1391

Query: 1638 VRRQEQPSIESTSPI----SRTDEIRKNTYRTLDSLEQTIKQLENTISEM-SPKALVDTS 1692
             +     +   +SP+     RT    +++  +   ++  + +  +  S   S   L D S
Sbjct: 1392 EKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS 1451

Query: 1693 CSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPT--SIPSASRKGSSGAPQTSRMPV 1750
             + +R S++ SS   ++    P     E  ++ EP      P    +  S     ++   
Sbjct: 1452 GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT 1511

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1810
            P   + R G+     +++  + P   R  +GS+++   D KP++     S+  + SP S 
Sbjct: 1512 PQ--RERSGSESSVDQKTVARTPLGQRSRSGSSQEL--DVKPSASPQERSESDS-SPDSK 1566

Query: 1811 KSSSLP----SSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQS 1866
              +  P    S SG S  + +     P  + +  SP+      +A    S S+ S + ++
Sbjct: 1567 AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKA 1626

Query: 1867 LTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKA 1926
                      S S  S  GR P P   SS+  SP          +G+R+   P   S   
Sbjct: 1627 PAPRALPRR-SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685

Query: 1927 QNGSSSKATPSTAKE 1941
                SS+++P   ++
Sbjct: 1686 PRRRSSRSSPELTRK 1700



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 65/249 (26%), Positives = 94/249 (37%), Gaps = 45/249 (18%)

Query: 1666 LDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTAL 1725
            L +L+   ++  ++ S  S  +   +S SS+  S + SS    E S  P+  P+     +
Sbjct: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ-PEVALKRV 2579

Query: 1726 EPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKK 1785
              PT  P         A +  R P P  AK +                   R+++ S+  
Sbjct: 2580 PSPTPAPKE-------AVREGRPPEPTPAKRK-------------------RRSSSSSSS 2613

Query: 1786 SGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTG 1845
            S      +S S  +S     S SS  SSS  SSS  SS+ P+P    P     P SP+  
Sbjct: 2614 SSSSSSSSSSSSSSS-----SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP 2668

Query: 1846 PPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVS 1905
            PP    S  P     SL+            LS+SP  +   +P P     SP    SS S
Sbjct: 2669 PPGERRSRSPRKPIDSLR--------DSRSLSYSPVERRRPSPQP-----SPRDQQSSSS 2715

Query: 1906 LNQGAKGTR 1914
                 +G R
Sbjct: 2716 ERGSRRGQR 2724



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 62/241 (25%), Positives = 90/241 (37%), Gaps = 25/241 (10%)

Query: 1708 QEASPRPLLVPDEGPTALEPPTSIP-SASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGK 1766
            ++++ RP   P+   T  EPP   P  A R G S  P  +  P+     N P        
Sbjct: 344  EKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQP-LATTPLSQEPVNPPSEASPTRD 402

Query: 1767 QSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLP 1826
            +S  + P +  Q++ S++ S    +PT  S  AS     SP S K +  P S  + S+ P
Sbjct: 403  RSPPKSPEKLPQSS-SSESSPPSPQPTKVSRHASS----SPESPKPAPAPGSHREISSSP 457

Query: 1827 NPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQ--- 1883
                     A    S    P           +    + +S T T +GH  S SPQ +   
Sbjct: 458  TSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSR 517

Query: 1884 ------NGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPS 1937
                    R+P     S SP  P  S S N   +G          S  A+ G S   +P+
Sbjct: 518  SAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG---------RSRSARRGRSHSRSPA 568

Query: 1938 T 1938
            T
Sbjct: 569  T 569



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 96/475 (20%), Positives = 184/475 (38%), Gaps = 52/475 (10%)

Query: 1470 ELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLR-TGQQVETKSQPHSLAT 1528
            ELE MM E+  EE++ +E   +         +  K V PG    T  Q    ++ H LA 
Sbjct: 72   ELEEMMEEQGYEEQQIQEKVATF-----RLMLLEKDVNPGGKEETPGQRPAVTETHQLA- 125

Query: 1529 ETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQA 1588
                    E+N  +  +       +       + D Q  + + K     P K  + + ++
Sbjct: 126  --------ELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRES 177

Query: 1589 IRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIES 1648
              + + T K+  +    +      +    +E K+    +    ++ E+  R+   P+ +S
Sbjct: 178  SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES-ESKKRKHRSPTPKS 236

Query: 1649 TSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQ 1708
                 ++ + ++   R+     ++ +   +T ++ +  +  DTS S +R S A+ +H   
Sbjct: 237  KR---KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS--DTSRSRSR-SAAAKTHT-- 288

Query: 1709 EASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQS 1768
                          TAL   +  P++ R+G   AP +          + P T  K    S
Sbjct: 289  --------------TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQ-PSS 333

Query: 1769 KLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNP 1828
              +D  + ++   + + S    + ++   P +  P L+   G S    +++  S    NP
Sbjct: 334  PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393

Query: 1829 P--ATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGR 1886
            P  A+     S P SP+  P + S+   P          S   T    H S SP+S    
Sbjct: 394  PSEASPTRDRSPPKSPEKLPQSSSSESSPP---------SPQPTKVSRHASSSPESPK-P 443

Query: 1887 APPPLSFSSSPPSPASSVSLNQGAKGTRT-IHTPSLTSYKAQNGSSSKATPSTAK 1940
            AP P S      SP S    +  AK  ++  HTPS    ++++ +++K   S ++
Sbjct: 444  APAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 74/298 (24%), Positives = 116/298 (38%), Gaps = 47/298 (15%)

Query: 1679 TISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKG 1738
            T + M+P AL   + +S R  +++   ++   SP PLL      T    P S PS SR  
Sbjct: 2367 TSARMAP-ALSGANLTSPRVPLSAYERVSGRTSP-PLLDRARSRT----PPSAPSQSRMT 2420

Query: 1739 SSGAPQ-TSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSL 1797
            S  AP  +SRM    S    P   D+P          Q R          G     S SL
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG-----SQSL 2475

Query: 1798 PASKIPALSPSSGKSS---SLPSSSGDSSNLPNPPATKPSIASNPL-----------SPQ 1843
             +  +   + S+G  +   S+P+     S++  PPA+  +   + L           S  
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSS 2535

Query: 1844 TGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQS----------------QNGRA 1887
            +   + S+S   S S+ S    S +   +G  L   P+                 + GR 
Sbjct: 2536 SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP 2595

Query: 1888 PPPLSF-----SSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAK 1940
            P P        SSS  S +SS S +  +  + +  + S +S  + + SSS ++PS AK
Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 96/437 (21%), Positives = 152/437 (34%), Gaps = 65/437 (14%)

Query: 1502 SHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTELN--KFSHVDSPNSECKGE 1559
            SH +      R+G   E K++  +    +R+    EM ++ ++  +   + SP S+ K  
Sbjct: 713  SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 1560 DATDDQF--ESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQH 1617
             +        SP  K K + P ++        R+G+   K                 K  
Sbjct: 773  LSLRRSLSGSSPCPKQKSQTPPRR-------SRSGSSQPK----------------AKSR 809

Query: 1618 KEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLE 1677
               +R   + S P      T  RQ   S      +      R+ +  +  + EQ++    
Sbjct: 810  TPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR 869

Query: 1678 NTISEMSPKALVDT------SCSSN-----RDSVASSSHIAQEASPRPLLVPDEGP-TAL 1725
             +  E SP   + +      SCS +     + S       ++ +SP+P +     P    
Sbjct: 870  RSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRS 929

Query: 1726 EPPTSIPSASRKGSSGAPQTSRMPVPMS--------AKNRPGTLDKPGKQSKLQDPRQYR 1777
               +S PS SR  S   P+ SR   P S          +  G+     K      PRQ  
Sbjct: 930  HSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSH 989

Query: 1778 QANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKS------SSLPSSSGDSSNLPNPPAT 1831
              + S         P  PSL  SK P     S  S       SL   +G  S+ P P  +
Sbjct: 990  SGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTP-PGES 1048

Query: 1832 KPSIASNPL--SPQTGPPAHSASLIPSV-----SNGSLKFQSLTHTGKGHHLSFSPQSQN 1884
               ++S  L    QT P   S +  P V      + SL+ +S T    G   S SP ++ 
Sbjct: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108

Query: 1885 GRAPPPL----SFSSSP 1897
                P       FS+SP
Sbjct: 1109 ASRSPIRQDRGEFSASP 1125



 Score = 38.9 bits (89), Expect = 0.049
 Identities = 74/336 (22%), Positives = 113/336 (33%), Gaps = 26/336 (7%)

Query: 293  DGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPS----------PSRIPYGGTRSMVVPG 342
            D P  P  G +       P + P TP P S  PS          P R   G   S+    
Sbjct: 1468 DIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527

Query: 343  NATIPRDRISSLPVSRPISPSPSAILERR---DVKPDEDMSGKNIAMYRNEGFYADPYLY 399
             A  P  + S    S+ +   PSA  + R   D  PD     +     R+    + P + 
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS-GSSPEVD 1586

Query: 400  HEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYP 459
             + R+S   S  G   +V D   A  R    S S+   P   A   + +   R +S    
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS-PEPKAPAPRALPR---RSRSGSSS 1642

Query: 460  DSHLPT-LGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEP--- 515
                P+  GS +  +SP      R     A   +   P      R  P R++ +  P   
Sbjct: 1643 KGRGPSPEGSSSTESSPEHPPKSRT----ARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698

Query: 516  GTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTG 575
                   + RSA+         PP   +     S     K R +R R  A   +  + + 
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758

Query: 576  LVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSA 611
              +S   K      S+  S  +  +TT  R+ + S+
Sbjct: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSS 1794



 Score = 38.1 bits (87), Expect = 0.084
 Identities = 128/616 (20%), Positives = 211/616 (34%), Gaps = 93/616 (15%)

Query: 20   RQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRS-SKEI 78
            R  Q +G+     +S E     RT +R S  NS   + KS  +  R  +L  PRS +K  
Sbjct: 716  RTPQRRGRSG---SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 79   LGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQT--RSPKLSHSPQPPSLGDP 136
            L ++ S       +     K + P   S     Q + + +T  R  + S SP P      
Sbjct: 773  LSLRRS---LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKT 829

Query: 137  VEHLSETSADSLEAMSEGDAP---------------TPFSRGSRTRASLPVVRSTNQTKE 181
                S +S+     +  G  P               TP  R     +  P ++S   ++ 
Sbjct: 830  PSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRH 889

Query: 182  RSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESR 241
               G    +    T   + P+  +S        +S  P+Q +     SPS +      + 
Sbjct: 890  SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS--PRQRSHSGSSSPSPSRVTSRTTP 947

Query: 242  NVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPG 301
                 ++   N++ R L +      +H+ + +P     D +++ E        P     G
Sbjct: 948  RRSRSVSPCSNVESRLLPRY-----SHSGSSSP-----DTKVKPETP------PRQSHSG 991

Query: 302  STAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMV--VPGNATIPRDRISSLPVSRP 359
            S +  P     +PP   +  S  P P         S+V   PG+ ++     SS P    
Sbjct: 992  SISPYPKVKAQTPPGPSLSGSKSPCPQE---KSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048

Query: 360  ISPSPSAILE-RRDVKPDE--DMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLD 416
                 S  L+ +    PD   D S   +    +E     P L  + +    S  GG    
Sbjct: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSES----PSLQSKSQ---TSPKGGRSRS 1101

Query: 417  VPDHIIAYHRTAIRS--ASAYCNPSMQAEMHMEQSLYRQKSRKYP---------DSHLPT 465
                     R+ IR        +P +++ M  EQS ++  S  YP          S L T
Sbjct: 1102 SSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLET 1161

Query: 466  LGSK----TPPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYI 521
              SK     PP      S  R  D  + +     P          S   FK    TL   
Sbjct: 1162 AESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPE---------SSLVFK---DTLRTP 1209

Query: 522  EKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSAL 581
             + RS AG S       P  ++Q  A  T++  +D E  E ++  E+    +   + S L
Sbjct: 1210 PRERSGAGSS-------PETKEQNSALPTSS--QDEELMEVVEKSEEPAGQILSHLSSEL 1260

Query: 582  FKGPITSYSKDASSEK 597
             +   +++      E+
Sbjct: 1261 KEMSTSNFESSPEVEE 1276



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 89/461 (19%), Positives = 158/461 (34%), Gaps = 49/461 (10%)

Query: 1502 SHKKVAPGNLRTGQQVETKSQPHSL---------ATETRNPGGQEM-NRTELNKFSHVDS 1551
            S  +++P   R+G   E K +P +          + E + P  + +  R+     S    
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646

Query: 1552 PNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEED 1611
            P+ E  G  +T+   E P        PK + A          KT  +T           +
Sbjct: 1647 PSPE--GSSSTESSPEHP--------PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE 1696

Query: 1612 GTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQ 1671
             T K  + ++R   A S PE       R +  PS+ S  P  ++   R+   R+  S   
Sbjct: 1697 LTRKA-RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR--RSASSPRT 1753

Query: 1672 TIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSI 1731
                         P+ L  +   S R+   ++    +  S +            +   S 
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ------STSRRRQRSRSR 1807

Query: 1732 PSASRKGSSGAPQTSRMPVPM-----SAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKS 1786
               +R+   G+   SR P        S++ R G    P    K     + R +    K+S
Sbjct: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS---RSRTSPAPWKRS 1864

Query: 1787 GGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGP 1846
                 P +     S+ P +S    +S + P S   S +  +    +    ++P+S +   
Sbjct: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRR--- 1921

Query: 1847 PAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSP-----QSQNGRAPPPLSFSSSPPSPA 1901
               S S  P V+    + +S T T +    S +P     +S++   P     S S  SP 
Sbjct: 1922 --RSRSRTPPVTR--RRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPI 1977

Query: 1902 SSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKET 1942
            +               + S TS   +  S S+ +P T + +
Sbjct: 1978 TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2018



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 61/251 (24%), Positives = 94/251 (37%), Gaps = 22/251 (8%)

Query: 1626 ARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSP 1685
            +RS+         R +  P+I   S  SRT  + +   R+   L    +    T      
Sbjct: 2006 SRSRTSPVTRRRSRSRTPPAIRRRSR-SRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARG 2064

Query: 1686 KALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQT 1745
            K  +  S  + R   AS S   +  S  P    +   +   PP ++ S SR      P  
Sbjct: 2065 KRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRT-PPVALNS-SRMSCFSRPSM 2122

Query: 1746 SRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG----DFKPTS------P 1795
            S  P P+     PG L+  G         Q  QA GS     G    D + TS       
Sbjct: 2123 S--PTPLDRCRSPGMLEPLGSSRTPMSVLQ--QAGGSMMDGPGPRIPDHQRTSVPENHAQ 2178

Query: 1796 SLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIP 1855
            S  A  + A+S  + +     S++G ++ +   PA  P      +S +T P A+ AS IP
Sbjct: 2179 SRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPL-----MSLRTAPAANLASRIP 2233

Query: 1856 SVSNGSLKFQS 1866
            + S  ++   S
Sbjct: 2234 AASAAAMNLAS 2244



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 55/242 (22%), Positives = 81/242 (33%), Gaps = 24/242 (9%)

Query: 1721 GPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQAN 1780
            G +    P      SR  +      SR   P   ++R  +L + G+       R+ R  +
Sbjct: 667  GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726

Query: 1781 GSAKKSGGDFKP------TSPSLPASKIPAL------SPSSGKSS--SLPSSSGDSSNLP 1826
             S +K+            +SP +  S+I +       SP S   S  SL  S   SS  P
Sbjct: 727  SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786

Query: 1827 N-----PPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQ 1881
                  PP    S +S P +    PP  S S     S+     Q      +  H S SP 
Sbjct: 787  KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS-----SSSPPPKQKSKTPSRQSHSSSSPH 841

Query: 1882 SQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKE 1941
             +     PP   S + P         Q      +   P L S      S S ++P   K 
Sbjct: 842  PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901

Query: 1942 TS 1943
            ++
Sbjct: 902  ST 903



 Score = 35.4 bits (80), Expect = 0.55
 Identities = 46/190 (24%), Positives = 70/190 (36%), Gaps = 16/190 (8%)

Query: 1634 PENTVRRQEQPS------IESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKA 1687
            PE  ++R   P+      +    P   T   RK   R+  S   +     ++ S  S  +
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR--RSSSSSSSSSSSSSSSSSSSSSSS 2629

Query: 1688 LVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSR 1747
               +S SS+  S +SSS     A P P  +P        PP    S S +    + + SR
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689

Query: 1748 MPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASK-IPALS 1806
                 S    P    +P  Q   +D +      GS +   GD +  SPS    +  P+  
Sbjct: 2690 -----SLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR--SPSHKRRRETPSPR 2742

Query: 1807 PSSGKSSSLP 1816
            P   +SS  P
Sbjct: 2743 PMRHRSSRSP 2752



 Score = 35.0 bits (79), Expect = 0.71
 Identities = 40/194 (20%), Positives = 58/194 (29%), Gaps = 24/194 (12%)

Query: 1009 PATGPLPRGDAPVDKVELSE--------------DSPNSEQDLEKLGGKSPPPPPPPPRR 1054
            PA+G    GDAP  +   +                SP  ++D +K    +  P P P R 
Sbjct: 298  PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERS 357

Query: 1055 SYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGP----------SPQTRATKYPAEEP 1104
            S  P     T    +      +   T   S E   P          SP     K P    
Sbjct: 358  STGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSS 417

Query: 1105 ASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVK 1164
            + +  PSP P   S       E  +        +           S+  A+  ++ SH  
Sbjct: 418  SESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTP 477

Query: 1165 DTRSGATVPPKEKK 1178
              R G +  P   K
Sbjct: 478  SRRMGRSRSPATAK 491



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 40/180 (22%), Positives = 73/180 (40%), Gaps = 4/180 (2%)

Query: 1745 TSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPA 1804
            T+R P  MSA      + +      L   R    AN +++         + +L +++ PA
Sbjct: 2192 TARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAAS--AAAMNLASARTPA 2249

Query: 1805 LSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKF 1864
            +  +   + S   ++  + NL +P       A N   P+T P A + +L  + +  +L  
Sbjct: 2250 IPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRT-PTAPAVNLAGARTPAALAA 2308

Query: 1865 QSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLN-QGAKGTRTIHTPSLTS 1923
             SLT +G     +  P S      P  +    P S  ++  +N  G++    +   SLTS
Sbjct: 2309 LSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTS 2368


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 108/504 (21%), Positives = 181/504 (35%), Gaps = 63/504 (12%)

Query: 1452 DIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNL 1511
            ++R+  K   T     D  + R +  +K   E   ++ DS     ++S  SH+   P + 
Sbjct: 1918 ELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDS-----SSSLSSHRYETPSDA 1972

Query: 1512 RTGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKK 1571
                   +   P     +T  P   + N+ E +     + P    +       Q ESP  
Sbjct: 1973 IEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYR------PQQESPS- 2025

Query: 1572 KFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQH------KEAKRFEI 1625
                  P++QL   +QA   G     +T +++         TL  H      ++  R ++
Sbjct: 2026 ------PQQQLPPSSQA--EGMGQVPRTHRLI---------TLADHICQIITQDFARNQV 2068

Query: 1626 ARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSP 1685
            +   P+  P +T   Q  PS   ++P+      R +      S+       +   S +SP
Sbjct: 2069 SSQTPQQPPTSTF--QNSPSALVSTPVRTKTSNRYSPESQAQSVHH-----QRPGSRVSP 2121

Query: 1686 KALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQT 1745
            + LVD S  S        SH++ E  P   + P + P   E   S+   S++G+  A Q 
Sbjct: 2122 ENLVDKSRGSRPGKSPERSHVSSE--PYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQR 2179

Query: 1746 SRMPVPMSAKNRPGTLDK-----PGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPAS 1800
            +    P S    P    K     P  +SK Q+   +R+ N S      D     P     
Sbjct: 2180 NDARSPGSISYLPSFFTKLENTSPMVKSKKQE--IFRKLNSSG-GGDSDMAAAQPGTEIF 2236

Query: 1801 KIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIA---SNPLSPQTGPPAHSASLIPSV 1857
             +PA++ S   SS   S +  +SNL      + ++     + +       +    ++P  
Sbjct: 2237 NLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGT 2296

Query: 1858 SNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIH 1917
            +N S+     T   +G      P   +G    P   S S    + S    QG  GT    
Sbjct: 2297 ANTSVVTSGETRREEG-----DPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGT---E 2348

Query: 1918 TPSLTSYKAQNGSSSKATPSTAKE 1941
             PS  S     G   + TP  A E
Sbjct: 2349 RPSSVSSVHSEGDYHRQTPGWAWE 2372



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 56/275 (20%), Positives = 96/275 (34%), Gaps = 42/275 (15%)

Query: 1606 EEEEEDGTLKQHK--EAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTY 1663
            EE+EED   K  K  E K+ E  + + ED+ ENT   +E+  I+ T+    T+E      
Sbjct: 515  EEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENT---KEKDKIDGTA--EETEE------ 563

Query: 1664 RTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPT 1723
                  EQ   +   T +    +    T   +N  + AS++  A    P P L P   P 
Sbjct: 564  -----REQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPI 618

Query: 1724 ALEPPTS----------------------IPSASRKGSSGAPQTSRMPVPMSAKNRPGTL 1761
            + EP  +                         A   G+    Q          ++    L
Sbjct: 619  STEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNL 678

Query: 1762 DKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGD 1821
             +  KQ   + PR+ R  +     +          + AS     +P   +  ++  S   
Sbjct: 679  LQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASN-EEENPEDSEVEAVKPSEDS 737

Query: 1822 SSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPS 1856
              N  +   T+P++   P + +T P    +  +PS
Sbjct: 738  PENATSRGNTEPAVELEP-TTETAPSTSPSLAVPS 771


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 78/318 (24%), Positives = 116/318 (36%), Gaps = 38/318 (11%)

Query: 1632 DTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDT 1691
            D P+N + ++  P      P  +         +++ +L    ++L + +S  SPK    T
Sbjct: 93   DKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLT 152

Query: 1692 SCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTS-RMPV 1750
                 +     S  + Q   P P        ++ EPP S+P    +  +  P    + P 
Sbjct: 153  PLEPQKPGSVVSPEL-QTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPA 211

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPAS-----KIPAL 1805
            P+S ++   TL  P  Q +   P      + S+        P SP L AS       PA 
Sbjct: 212  PVSPESVKATLSNPKPQKQSHFPETLGPPSASS--------PESPVLAASPEPWGPSPAA 263

Query: 1806 SPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQ 1865
            SP S KS+   S        P P    PS +  P  P            P+VS GS K  
Sbjct: 264  SPESRKSARTTS--------PEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWK-- 313

Query: 1866 SLTHTGKGHHLSFSPQSQNG---RAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLT 1922
                 G       +P + +G    A P  S S  P  P  SVS            TPS++
Sbjct: 314  -PGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKP------TPSVS 366

Query: 1923 SYKAQNGSSSKATPSTAK 1940
            S    +  SS  +PS+ K
Sbjct: 367  S---ASWKSSSVSPSSWK 381


>gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo
            sapiens]
          Length = 685

 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 109/460 (23%), Positives = 183/460 (39%), Gaps = 34/460 (7%)

Query: 1468 DEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLA 1527
            +EEL R  +EEK  +EE  +    +  +     M+ +     +   G  +E KS+    A
Sbjct: 52   EEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYNGIPIEEKSKKRQ-A 110

Query: 1528 TETRNPGG--QEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAA- 1584
            TE+    G  +E    E N+F   +   SE + E    ++ E PK + K K P K     
Sbjct: 111  TESHTSQGTDREYEMEEENEFLEYNHAESEQEYE----EEQEPPKVESKPKVPLKSAPPP 166

Query: 1585 --LTQAIRTGTKTGKKTLQV-VVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPEN----T 1637
               T  +R   K   + +++ VV + EE   T ++ +E +  E    + +   +     T
Sbjct: 167  MNFTDLLRLAEKKQFEPVEIKVVKKSEERPMTAEELREREFLERKHRRKKLETDGKLPPT 226

Query: 1638 VRRQEQPSIEST-SPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSN 1696
            V ++     ES  + +S+    R  + + +  L    K+   +++     AL  +     
Sbjct: 227  VSKKAPSQKESVGTKLSKGSGDRHPSSKGM-PLPHAEKKSRPSMANEKHLALSSSKSMPG 285

Query: 1697 RDSVASSSHIAQ----EASPRPLLVPDEGPTALEPPTSIP--SASRKGSSGAPQTSRMPV 1750
                A S + +Q    E   +P+      P +     S+P  SASR   S     ++  +
Sbjct: 286  ERIKAGSGNSSQPSLREGHDKPVFNGAGKPHSSTSSPSVPKTSASRTQKSAVEHKAKKSL 345

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSA--KKSGGDFKPTSPSLPASKIPALSPS 1808
               + +RPG +  P  ++K    RQ   ++ SA  + S G  +PT  S P  +    S S
Sbjct: 346  SHPSHSRPGPMVTPHNKAKSPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVPRRQNGSSS 405

Query: 1809 SGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLT 1868
            SG   S+ S S   +N  NP     S    P  P +        +  SVS+      S  
Sbjct: 406  SGPERSI-SGSKKPTNDSNPSRRTVSGTCGPGQPASSSGGPGRPISGSVSSARPLGSS-- 462

Query: 1869 HTGKGHHLSFSP----QSQNGRAPPPLSFSSSPPSPASSV 1904
              G G  +S SP    +  +G  PP  S S    S + S+
Sbjct: 463  -RGPGRPVS-SPHELRRPVSGLGPPGRSVSGPGRSISGSI 500


>gi|239742580 PREDICTED: similar to Putative POM121-like protein
            1-like [Homo sapiens]
          Length = 897

 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 79/317 (24%), Positives = 127/317 (40%), Gaps = 33/317 (10%)

Query: 1620 AKRFEIARSQPEDTPE--NTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLE 1677
            A+R E+  +Q   T    + ++R    S  S S      E+++       S  Q      
Sbjct: 368  AQRSEVRYNQRSQTSRTRSCLKRNASSSSSSHSSTEGLQELKRRR-GPASSHCQLAHSSS 426

Query: 1678 NTISEMSPKALVDTSCSSNRDSVASSSHIAQEA-SPRP----------LLVPDEGPTALE 1726
            NT+SE  P+A+       N+   A    +A    SPR           L V D+  +   
Sbjct: 427  NTVSEDGPQAVSSGHRCENKAGTAPGQTLAPRGGSPRSQASRPHINSALYVEDKAISDCR 486

Query: 1727 P--PTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAK 1784
            P  P+   S+   G+SG P  S+ P   + ++RP + D  G  + L       +   +A 
Sbjct: 487  PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASA---AEVPSTAP 543

Query: 1785 KSGGDFKPTSPSLPAS-KIPALSPSSGKSSSLPS--------SSGDSSNLPNPPATK-PS 1834
             SG   +P  P   +S  +PA S  S  S+ + S        +S D+      P T  P+
Sbjct: 544  VSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSLIPATFTAASRDAGMRRTRPGTSAPA 603

Query: 1835 IASNPLSPQTGPPAHSASLIPSVSNGSLKF-QSLTHTGKGH--HLSFSPQSQNGRAPPPL 1891
             A+  L P T  P  S SL+ +V  G   F  S T   +     + ++ +SQ  R    L
Sbjct: 604  AAAAALPPSTLNPT-SGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQTSRTRSCL 662

Query: 1892 SFSSSPPSPASSVSLNQ 1908
              ++S  S +S+  L +
Sbjct: 663  KRNASSSSHSSTEGLQE 679



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 58/229 (25%), Positives = 93/229 (40%), Gaps = 26/229 (11%)

Query: 1620 AKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENT 1679
            A+R E+  +Q   T       +   S  S S      E+++       S  Q      NT
Sbjct: 642  AQRSEVRYNQRSQTSRTRSCLKRNASSSSHSSTEGLQELKRRR-GPASSHCQLAHSSSNT 700

Query: 1680 ISEMSPKALVDTSCSSNRDSVASSSHIA--------QEASPR---PLLVPDEGPTALEP- 1727
            +SE  P+A+       N+   A    +A        Q + PR    L V D+  +   P 
Sbjct: 701  VSEDGPQAVSSGHRCENKAGTAPGQTLAPRGGYPRSQASRPRINSALHVEDKAISDCRPS 760

Query: 1728 -PTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKS 1786
             P+   S+   G+SG P  S+ P   + ++RP + D  G  + L       + + +A  S
Sbjct: 761  RPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASA---AEVSSTAPVS 817

Query: 1787 GGDFKPTSPSLPAS-KIPALSPSSGKSSSLPSSSGDSSNLPNP--PATK 1832
            G   +P  P   +S  +PA S  SG S+       D+S +P P  PA++
Sbjct: 818  GKKHRPPGPLFSSSDPLPATSSHSGDSAQ------DTSLIPAPFTPASR 860



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 56/242 (23%), Positives = 100/242 (41%), Gaps = 23/242 (9%)

Query: 1700 VASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPG 1759
            + S+ H+  +A      +PD  P+    P+   S+   G+SG P  S+ P   + ++RP 
Sbjct: 200  INSALHVEDKA------IPDCRPSR---PSHTLSSLATGASGGPPVSKAPTMDAQQDRPK 250

Query: 1760 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPAS-KIPALSPSSGKSSSLPSS 1818
            + D  G  + L       +   +A  SG   +P  P   +S  +PA S  S  ++ + S 
Sbjct: 251  SQDCLGLVAPLASA---AEVPSTAPVSGKKHRPPGPLFSSSDPLPATSYHSRDTAQVTSL 307

Query: 1819 SGDSSNLPNPPATKPSIASNPLSPQTGPPAH-----SASLIPSVSNGSLKF-QSLTHTGK 1872
               +    +  A      S P +    PP       S SL+ +V  G   F  S T   +
Sbjct: 308  IPATFTAASRDAGMRRTRSAPAAATAAPPPSTLNNTSGSLLNAVDGGPSHFLASATAAAR 367

Query: 1873 GH--HLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGS 1930
                 + ++ +SQ  R    L  ++S  S +SS S  +G +  +    P+ +  +  + S
Sbjct: 368  AQRSEVRYNQRSQTSRTRSCLKRNAS--SSSSSHSSTEGLQELKRRRGPASSHCQLAHSS 425

Query: 1931 SS 1932
            S+
Sbjct: 426  SN 427


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 72/271 (26%), Positives = 99/271 (36%), Gaps = 55/271 (20%)

Query: 1694 SSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTS---------IPSASRKGSSGAPQ 1744
            ++NRD+ +  S        RP L+P  G +    P S         +PS   +     PQ
Sbjct: 114  TANRDNDSGGS--------RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQ 165

Query: 1745 TSRMPVPM-SAKNRPGTLDKPGKQSKLQDPRQYRQA---NGSAKKSGGDFKP----TSPS 1796
             +RMP P     ++P ++  P   +    PR  + +    GS    GG  +P    T P 
Sbjct: 166  RNRMPPPRPDVGSKPDSIPPPVPST----PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221

Query: 1797 LPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLI-- 1854
             P ++  AL   S + S L SSS  S+  P PP   PS A +   P   PP  +   I  
Sbjct: 222  FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT--PSRALDDKPPPPPPPVGNRPSIHR 279

Query: 1855 -----PSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQG 1909
                 P   N      S            S  SQ    PPP S    PP P SS   ++ 
Sbjct: 280  EAVPPPPPQNNKPPVPSTPRP--------SASSQAPPPPPPPSRPGPPPLPPSSSGNDE- 330

Query: 1910 AKGTRTIHTPSLTSYKAQNGSSSKATPSTAK 1940
                    TP L        SS+   PS  +
Sbjct: 331  --------TPRLPQRNLSLSSSTPPLPSPGR 353



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 63/272 (23%), Positives = 98/272 (36%), Gaps = 21/272 (7%)

Query: 1643 QPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVAS 1702
            Q  + S+SP S    +     R LD               +  +A+      +N+  V S
Sbjct: 237  QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS 296

Query: 1703 SSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLD 1762
            +   +  +   P   P   P+   PP   PS+S  G+   P+  +  + +S+   P  L 
Sbjct: 297  TPRPSASSQAPP---PPPPPSRPGPPPLPPSSS--GNDETPRLPQRNLSLSSSTPP--LP 349

Query: 1763 KPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDS 1822
             PG+   L  P   R      +   G   P  P  P S+  + S +   +  LPS SG  
Sbjct: 350  SPGRSGPLPPPPSERPPP-PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVD 408

Query: 1823 SNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQ-SLTHTGKGHHLSFSPQ 1881
            S    P    P    +  +P   PP+       S+ NG   FQ S           F P 
Sbjct: 409  SPRSGPRPPLPPDRPSAGAPPPPPPS------TSIRNG---FQDSPCEDEWESRFYFHPI 459

Query: 1882 SQNGRAPPPLSFSSSPPSPASSVSLNQGAKGT 1913
            S     PPP  +  +  S  S ++ N+   G+
Sbjct: 460  SD---LPPPEPYVQTTKSYPSKLARNESRSGS 488



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 38/136 (27%), Positives = 53/136 (38%), Gaps = 25/136 (18%)

Query: 983  NGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGG 1042
            +G +    L +   ++  S P L  P  +GPLP           SE  P   +D     G
Sbjct: 326  SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP--------SERPPPPVRDPP---G 374

Query: 1043 KSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAE 1102
            +S P PPPPP            +R+G    T R    T +  S     SP++        
Sbjct: 375  RSGPLPPPPP-----------VSRNGS---TSRALPATPQLPSRSGVDSPRSGPRPPLPP 420

Query: 1103 EPASAWTPSPPPVTTS 1118
            +  SA  P PPP +TS
Sbjct: 421  DRPSAGAPPPPPPSTS 436



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 6/107 (5%)

Query: 274 PKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP---HSMPPSPSRI 330
           P+     M   R  V ++ D    P P ST  P  + P++  S PVP       P P+  
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVP-STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220

Query: 331 PYGGTRSMVVPGNATIPRDRISSLPVSR--PISPSPSAILERRDVKP 375
           P+ G R   + G +       SS P S   P+ P+PS  L+ +   P
Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 27/72 (37%), Positives = 31/72 (43%), Gaps = 17/72 (23%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPR--DRIS 352
           P  PRP +++  P   P  PPS P P  +PPS S             GN   PR   R  
Sbjct: 295 PSTPRPSASSQAPP--PPPPPSRPGPPPLPPSSS-------------GNDETPRLPQRNL 339

Query: 353 SLPVSRPISPSP 364
           SL  S P  PSP
Sbjct: 340 SLSSSTPPLPSP 351



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 34/142 (23%), Positives = 47/142 (33%), Gaps = 36/142 (25%)

Query: 1002 IPNLEMPPATGPLPR----------GDAPVDKVELSEDSPNSEQD------LEKLGGKSP 1045
            +P     P+ GP P           G   + +  LS  SP S +          L  K P
Sbjct: 206  VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265

Query: 1046 PPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQT---RATKYPAE 1102
            PPPPP   R  +                  +E +       +  P P T    A+     
Sbjct: 266  PPPPPVGNRPSI-----------------HREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308

Query: 1103 EPASAWTPSPPPVTTSSSKDEE 1124
             P     P PPP+  SSS ++E
Sbjct: 309  PPPPPSRPGPPPLPPSSSGNDE 330


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 72/271 (26%), Positives = 99/271 (36%), Gaps = 55/271 (20%)

Query: 1694 SSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTS---------IPSASRKGSSGAPQ 1744
            ++NRD+ +  S        RP L+P  G +    P S         +PS   +     PQ
Sbjct: 114  TANRDNDSGGS--------RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQ 165

Query: 1745 TSRMPVPM-SAKNRPGTLDKPGKQSKLQDPRQYRQA---NGSAKKSGGDFKP----TSPS 1796
             +RMP P     ++P ++  P   +    PR  + +    GS    GG  +P    T P 
Sbjct: 166  RNRMPPPRPDVGSKPDSIPPPVPST----PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221

Query: 1797 LPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLI-- 1854
             P ++  AL   S + S L SSS  S+  P PP   PS A +   P   PP  +   I  
Sbjct: 222  FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT--PSRALDDKPPPPPPPVGNRPSIHR 279

Query: 1855 -----PSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQG 1909
                 P   N      S            S  SQ    PPP S    PP P SS   ++ 
Sbjct: 280  EAVPPPPPQNNKPPVPSTPRP--------SASSQAPPPPPPPSRPGPPPLPPSSSGNDE- 330

Query: 1910 AKGTRTIHTPSLTSYKAQNGSSSKATPSTAK 1940
                    TP L        SS+   PS  +
Sbjct: 331  --------TPRLPQRNLSLSSSTPPLPSPGR 353



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 63/272 (23%), Positives = 98/272 (36%), Gaps = 21/272 (7%)

Query: 1643 QPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVAS 1702
            Q  + S+SP S    +     R LD               +  +A+      +N+  V S
Sbjct: 237  QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS 296

Query: 1703 SSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLD 1762
            +   +  +   P   P   P+   PP   PS+S  G+   P+  +  + +S+   P  L 
Sbjct: 297  TPRPSASSQAPP---PPPPPSRPGPPPLPPSSS--GNDETPRLPQRNLSLSSSTPP--LP 349

Query: 1763 KPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDS 1822
             PG+   L  P   R      +   G   P  P  P S+  + S +   +  LPS SG  
Sbjct: 350  SPGRSGPLPPPPSERPPP-PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVD 408

Query: 1823 SNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQ-SLTHTGKGHHLSFSPQ 1881
            S    P    P    +  +P   PP+       S+ NG   FQ S           F P 
Sbjct: 409  SPRSGPRPPLPPDRPSAGAPPPPPPS------TSIRNG---FQDSPCEDEWESRFYFHPI 459

Query: 1882 SQNGRAPPPLSFSSSPPSPASSVSLNQGAKGT 1913
            S     PPP  +  +  S  S ++ N+   G+
Sbjct: 460  SD---LPPPEPYVQTTKSYPSKLARNESRSGS 488



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 38/136 (27%), Positives = 53/136 (38%), Gaps = 25/136 (18%)

Query: 983  NGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGG 1042
            +G +    L +   ++  S P L  P  +GPLP           SE  P   +D     G
Sbjct: 326  SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP--------SERPPPPVRDPP---G 374

Query: 1043 KSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAE 1102
            +S P PPPPP            +R+G    T R    T +  S     SP++        
Sbjct: 375  RSGPLPPPPP-----------VSRNGS---TSRALPATPQLPSRSGVDSPRSGPRPPLPP 420

Query: 1103 EPASAWTPSPPPVTTS 1118
            +  SA  P PPP +TS
Sbjct: 421  DRPSAGAPPPPPPSTS 436



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 6/107 (5%)

Query: 274 PKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP---HSMPPSPSRI 330
           P+     M   R  V ++ D    P P ST  P  + P++  S PVP       P P+  
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVP-STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220

Query: 331 PYGGTRSMVVPGNATIPRDRISSLPVSR--PISPSPSAILERRDVKP 375
           P+ G R   + G +       SS P S   P+ P+PS  L+ +   P
Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP 267



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 27/72 (37%), Positives = 31/72 (43%), Gaps = 17/72 (23%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPR--DRIS 352
           P  PRP +++  P   P  PPS P P  +PPS S             GN   PR   R  
Sbjct: 295 PSTPRPSASSQAPP--PPPPPSRPGPPPLPPSSS-------------GNDETPRLPQRNL 339

Query: 353 SLPVSRPISPSP 364
           SL  S P  PSP
Sbjct: 340 SLSSSTPPLPSP 351



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 34/142 (23%), Positives = 47/142 (33%), Gaps = 36/142 (25%)

Query: 1002 IPNLEMPPATGPLPR----------GDAPVDKVELSEDSPNSEQD------LEKLGGKSP 1045
            +P     P+ GP P           G   + +  LS  SP S +          L  K P
Sbjct: 206  VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265

Query: 1046 PPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQT---RATKYPAE 1102
            PPPPP   R  +                  +E +       +  P P T    A+     
Sbjct: 266  PPPPPVGNRPSI-----------------HREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308

Query: 1103 EPASAWTPSPPPVTTSSSKDEE 1124
             P     P PPP+  SSS ++E
Sbjct: 309  PPPPPSRPGPPPLPPSSSGNDE 330


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
            sapiens]
          Length = 699

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 65/311 (20%), Positives = 109/311 (35%), Gaps = 26/311 (8%)

Query: 839  AMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQ 898
            A +KA++++   S EE     G P      P          +      + SS        
Sbjct: 78   AKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDD 137

Query: 899  HSVALLNPAQN--LPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSV 956
                   P Q    P   ++ A P++A S+   S +    + P N     +    +  + 
Sbjct: 138  EEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTK 197

Query: 957  SAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPR 1016
            +    A +  K          +    +    +   E+A A   K++P  ++  A  P+  
Sbjct: 198  APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVV-AKAPVKA 256

Query: 1017 GDAPVDKVELSEDSPNSEQDLEKLGGKS--------PPPPPPPPRRSYLPGSGLTTTRSG 1068
               P  K   SEDS + E++ +K   K+        PPP  PPP++S      L T    
Sbjct: 257  ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKS------LGTQPPK 310

Query: 1069 DVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPV-------TTSSSK 1121
              V   +++ + +   S D   S      K P +   S  T  PPP        + SS  
Sbjct: 311  KAV--EKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDS 368

Query: 1122 DEEEEEEEGDK 1132
            D  E++E   K
Sbjct: 369  DSSEDDEAPSK 379



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 98/492 (19%), Positives = 162/492 (32%), Gaps = 75/492 (15%)

Query: 1472 ERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTG-------------QQVE 1518
            E    EE  ++++EE+     VQ     Q    K  P   ++              +  +
Sbjct: 125  ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184

Query: 1519 TKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFP 1578
             K  P ++  +T+ P        ++       S +S      + D + E      K   P
Sbjct: 185  PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244

Query: 1579 KKQLAALTQAIRTGTKTGKKTLQVVVYEEEEED--------------------------- 1611
            KKQ+ A        T T K +       +EEE+                           
Sbjct: 245  KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304

Query: 1612 GTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQ 1671
            GT    K  ++ +   S  + + E+    +E+    + + +S+         +  +S   
Sbjct: 305  GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSD 364

Query: 1672 TIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSI 1731
            +     +   E   K    T  SSN+ +V + S   + A+     V            S 
Sbjct: 365  SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSS 424

Query: 1732 PSASRKGSSGAPQTSRMPVPMSAK-NRPGTLDKPGKQ--------SKLQDPRQYRQANGS 1782
             S     SS   +T +M      K      L  P KQ        S   D     +    
Sbjct: 425  SSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEK 484

Query: 1783 AKKSGGDFKP------TSPSLPASKIPALSPSSGKSSSLPSSSGDSSNL-----PNPPAT 1831
              KS    KP       +PS PAS     + SS  SSS  SS  +   L     P P A 
Sbjct: 485  TSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAP 544

Query: 1832 KPSIASNPLSPQTGPPAHS----------ASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQ 1881
            K +  ++ L+ Q G  A +          A+++ S S GSLK +      K    + +PQ
Sbjct: 545  KAN-GTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKS-GSLKKRKQNEAAKE---AETPQ 599

Query: 1882 SQNGRAPPPLSF 1893
            ++  +   P +F
Sbjct: 600  AKKIKLQTPNTF 611



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 83/403 (20%), Positives = 136/403 (33%), Gaps = 47/403 (11%)

Query: 1544 NKFSHVDSPNSECKGEDATDDQFESPKKKFKF-----KFPKKQLAALTQAIRTGTKTGKK 1598
            N+ S V +  ++  G    D    S    + F     K P+++L A     +   K    
Sbjct: 25   NQLSEVANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASS 84

Query: 1599 TLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEI 1658
            +      EEEEE     Q   AK+  +   +    P     +  + S    S     +E 
Sbjct: 85   SDSEDSSEEEEE----VQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEED 140

Query: 1659 RKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVP 1718
            +K        +++ +K           KA      SS+ DS +SS               
Sbjct: 141  QKK-----QPVQKGVKPQAKAAKAPPKKAK-----SSDSDSDSSSE-------------- 176

Query: 1719 DEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQ 1778
            DE P   +P   I   + K  + AP       P  A  +  +       S   D  +  +
Sbjct: 177  DEPPKNQKP--KITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEK 234

Query: 1779 ANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASN 1838
            A  + KK+    K      P     A +P+   SSS  SSS +      P   KP   S+
Sbjct: 235  AAATPKKTVPK-KQVVAKAPVKA--ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291

Query: 1839 PLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPP---LSFSS 1895
               P   PP  S    P     +++ Q    + +         S+  + PP    +S ++
Sbjct: 292  VPPPSAPPPKKSLGTQP--PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349

Query: 1896 SPPSP----ASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKA 1934
            + P P    A S S +  +  +     PS  +   +N S+  A
Sbjct: 350  TKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPA 392



 Score = 38.1 bits (87), Expect = 0.084
 Identities = 99/524 (18%), Positives = 188/524 (35%), Gaps = 64/524 (12%)

Query: 1295 DTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDF---GQVVLR 1351
            D + Q +  G   + +          S    ++SS  D   ++Q+   T      Q    
Sbjct: 140  DQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAP 199

Query: 1352 PKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQKGEDI 1411
            PK AR A    N    SSSSS +  +++ D+       T  + +   +V          +
Sbjct: 200  PKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV-----VAKAPV 254

Query: 1412 QTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEEL 1471
            +      RK  +     +D E+      KKP   + ++P    S     +       + L
Sbjct: 255  KAATTPTRKSSSSEDSSSDEEEE----QKKP---MKNKPGPYSSVPPPSA---PPPKKSL 304

Query: 1472 ERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLATETR 1531
                 ++ +E+++  E+ +     +++S    KK  P       +  TK  P   A E+ 
Sbjct: 305  GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKK--PPTKAVVSKATTKPPPAKKAAESS 362

Query: 1532 NPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPK-KQLAALTQAIR 1590
            +      +           S + E   + A   +  S K     K P  K  AA  Q + 
Sbjct: 363  SDSSDSDS-----------SEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVG 411

Query: 1591 TGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTV----RRQEQPSI 1646
             G K    T +      EEE  + ++ K  K   +A ++P+ T +  +    ++  Q S 
Sbjct: 412  GGQKL--LTRKADSSSSEEESSSSEEEKTKKM--VATTKPKATAKAALSLPAKQAPQGSR 467

Query: 1647 ESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSP------KALVDTSCSSNRDSV 1700
            +S+S    +    +    +  ++++  +++    +   P      KA    S SS+  S 
Sbjct: 468  DSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSE 527

Query: 1701 ASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGT 1760
                 +  + SPRP      G +AL   T+    + K S    +  +    + +K+  G+
Sbjct: 528  EEEEKLKGKGSPRPQAPKANGTSAL---TAQNGKAAKNSEEEEEEKKKAAVVVSKS--GS 582

Query: 1761 LDK-------------PGKQSKLQDPRQYRQANGSAKKSGGDFK 1791
            L K               K+ KLQ P  + +     K++   F+
Sbjct: 583  LKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFR 626



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 53/227 (23%), Positives = 84/227 (37%), Gaps = 25/227 (11%)

Query: 1677 ENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDE-----GPTALEPPTSI 1731
            +N +SE++ K    T  ++ +D+ ASS         +   VP+      GP A +     
Sbjct: 24   DNQLSEVANKFAKATG-ATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKA 82

Query: 1732 PSASRKGSSG------APQTSRMPVPMSAKNRPGTLDKPGKQS-KLQDPRQYRQANGSAK 1784
             S+  + SS        P   +  VP      P     PGK + K  +     +++    
Sbjct: 83   SSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLP-----PGKAAAKASESSSSEESSDDDD 137

Query: 1785 KSGGDFKPTSPSL-PASKIPALSPSSGKSSSLPSSSGDSSNLPNPPAT-KPSIASNPLSP 1842
            +     +P    + P +K     P   KSS    S  DSS+   PP   KP I    +  
Sbjct: 138  EEDQKKQPVQKGVKPQAKAAKAPPKKAKSSD---SDSDSSSEDEPPKNQKPKITPVTVKA 194

Query: 1843 QTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPP 1889
            QT  P   A   P ++NG  K  S + +      S   + +   A P
Sbjct: 195  QTKAPPKPARAAPKIANG--KAASSSSSSSSSSSSDDSEEEKAAATP 239



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 46/216 (21%), Positives = 77/216 (35%), Gaps = 13/216 (6%)

Query: 985  KEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKS 1044
            +E EK  + A     + +     P       +G A       S+DS  SE++ EKL GK 
Sbjct: 480  EEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDS--SEEEEEKLKGKG 537

Query: 1045 PPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEP 1104
             P P  P       G+   T ++G       +E    K ++     S   +  K   E  
Sbjct: 538  SPRPQAPKAN----GTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRK-QNEAA 592

Query: 1105 ASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSH-- 1162
              A TP    +    + +   + ++G+K  +    F++    ++  +S    +  D+   
Sbjct: 593  KEAETPQAKKIKL-QTPNTFPKRKKGEKRAS--SPFRRVREEEIEVDSRVADNSFDAKRG 649

Query: 1163 -VKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENG 1197
               D    A    K  K   F HE  +K    Y  G
Sbjct: 650  AAGDWGERANQVLKFTKGKSFRHEKTKKKRGSYRGG 685


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 106/530 (20%), Positives = 177/530 (33%), Gaps = 69/530 (13%)

Query: 1468 DEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLA 1527
            DE+ ++   EEK    E+ E   S  +  + S    ++ +P   R  ++  ++S  H   
Sbjct: 148  DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR-RERKRSHSRSPRHRTK 206

Query: 1528 TETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKF----KFKFPKKQLA 1583
            + + +P  ++  +T       V       +   +T D  + PK +     K   P+K   
Sbjct: 207  SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSK 266

Query: 1584 ALTQAIRTGTKTGKKTLQVVVYEEEEEDGTL--KQHKEAKRFEIARSQPEDTPENTVRRQ 1641
               +  +T  ++  ++             T   ++H+   R    R +P      + RR+
Sbjct: 267  KEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326

Query: 1642 EQPSIESTSPISRTDE--IRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDS 1699
              P      P  R     +R+   R+  SL  +     ++ S   PK     + S  R  
Sbjct: 327  TPPRRMPPPPRHRRSRSPVRRRR-RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPR-- 383

Query: 1700 VASSSHIAQEASPRPLLVPDEGPTALEPP-------------------------TSIPSA 1734
               +  ++  ASP P       P A  PP                         TS    
Sbjct: 384  --KTRRLSPSASP-PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440

Query: 1735 SRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQS---KLQDPRQYRQANGSAKKSGGDFK 1791
              KG+      S  P P   +      DK GK +    +Q  RQYR+ N  +    G   
Sbjct: 441  KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500

Query: 1792 PTSPSLPA---------------SKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIA 1836
             +    P                S   + SPS  K     S  G     P+PP T+   +
Sbjct: 501  SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560

Query: 1837 SNPLSP------QTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPP 1890
             +P  P       T PP       P         +      + +  S  P+ +    PPP
Sbjct: 561  PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620

Query: 1891 LSFSSSP-PSPASSVSLN----QGAKGTRTIHTPSLTSYKAQNGSSSKAT 1935
                +SP P P   VS +    Q +       +PSL+S   +  S S++T
Sbjct: 621  PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 88/403 (21%), Positives = 149/403 (36%), Gaps = 52/403 (12%)

Query: 1578 PKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENT 1637
            P  Q +  T+  R     G+ + +V  ++  E+  +     + ++ E++ S+ +   +  
Sbjct: 415  PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474

Query: 1638 V-----------RRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSP- 1685
                        R+ +Q S +S S  S  DE  K ++     + +  +   +  +  SP 
Sbjct: 475  AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534

Query: 1686 KALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTS-IPSASRKGSSGAPQ 1744
            K   +TS    R    S     +  SP P   P    T   PP    PS   +  S +P+
Sbjct: 535  KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR 594

Query: 1745 TSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSA---KKSGGDFKPTSPSLPASK 1801
                P+       P     P +++    P   R+A+ S    ++      P   S P +K
Sbjct: 595  RYSPPIQRRYSPSP----PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650

Query: 1802 --IPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTG---PPAHSASLI-- 1854
               P+LS    K SS PS S   +  P P   + S +  P +PQT    PP    +    
Sbjct: 651  RRSPSLSSKHRKGSS-PSRSTREARSPQPNK-RHSPSPRPRAPQTSSSPPPVRRGASSSP 708

Query: 1855 -----PSVSNGSLKFQSLTHTGKGHHLSFSPQSQN-----------GRAPPPLSFSSSPP 1898
                 PS S   ++  S T   K    + SP  Q+           G   P      +PP
Sbjct: 709  QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP 768

Query: 1899 SPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKE 1941
            SP  S S         T  +P++   KA++ + S + P  + +
Sbjct: 769  SPVQSQS-------PSTNWSPAVPVKKAKSPTPSPSPPRNSDQ 804



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 80/371 (21%), Positives = 138/371 (37%), Gaps = 54/371 (14%)

Query: 1606 EEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRT---DEIRKNT 1662
            ++E++D   K+ KE+ R +  RS+   +P     R   P   S SP+ R       R   
Sbjct: 147  QDEDKDKRDKEEKESSREKRERSR---SPRRRKSRSPSPRRRS-SPVRRERKRSHSRSPR 202

Query: 1663 YRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDE-- 1720
            +RT         + +    E+ P+  V     S +++  S+S I +   P P+  P E  
Sbjct: 203  HRTKSRSPSPAPEKKEKTPEL-PEPSVKVKEPSVQEAT-STSDILKVPKPEPIPEPKEPS 260

Query: 1721 ----GPTALEPPTSIPSASRKGSSGAPQTSRMPV-------------PMSAKNRPGTLDK 1763
                     E   + P +  +  S +   SR P                S + RP    +
Sbjct: 261  PEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR 320

Query: 1764 PGKQSK-----LQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSS 1818
            P  + +     +  P ++R++    ++     + +S SL  S   + S SS +S S P  
Sbjct: 321  PSPRRRTPPRRMPPPPRHRRSRSPVRRR----RRSSASLSGS---SSSSSSSRSRSPPKK 373

Query: 1819 SGDSSNLP-------NPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTG 1871
                ++ P       +P A+ P     P  P T PP    S  P  SN + K +     G
Sbjct: 374  PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPG 433

Query: 1872 KGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSL---TSYKAQN 1928
            +        +    R  P    S +P      +S ++  KG +     S+     Y+ QN
Sbjct: 434  RTSGKVTKHKGTEKRESP----SPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489

Query: 1929 GSSSKATPSTA 1939
              SS  + S++
Sbjct: 490  QQSSSDSGSSS 500



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 65/297 (21%), Positives = 103/297 (34%), Gaps = 42/297 (14%)

Query: 911  PHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEK 970
            P V       QEATST  + + P+   IP           ++      K R  S  +++ 
Sbjct: 226  PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK-EKEKEKTRPRSRSRSKS 284

Query: 971  KWEEKRQNLDHYNGKEFEKLLEEA------QANIMKSIPNLEMPPATGPLP----RGDAP 1020
            +   + ++  H   +   +    +       +   +  P    PP   P P    R  +P
Sbjct: 285  RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP 344

Query: 1021 V-----DKVELSEDSPNSEQDLEKLGGKSPP--------------PPPPPPRRSYLPGSG 1061
            V         LS  S +S     +   K PP              P   PPRR + P   
Sbjct: 345  VRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP 404

Query: 1062 LTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSK 1121
             T         T ++ N T K+    +      + TK+   E   + +P+P P     S 
Sbjct: 405  ATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS- 463

Query: 1122 DEEEEEEEGDKIMAELQAFQKCSF--------MDVNSNSHAEPSRAD-SHVKDTRSG 1169
              E EE++G K+ A     Q+  +         D  S+S +E  R   SHVK+   G
Sbjct: 464  --ESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVG 518



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 37/134 (27%), Positives = 54/134 (40%), Gaps = 21/134 (15%)

Query: 1008 PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPP-------PPPRR--SYLP 1058
            P    P PR  +P  +   S   P   +        SPPPPP       PPP+R  S+ P
Sbjct: 586  PRRRSPSPRRYSPPIQRRYSPSPPPKRRTA------SPPPPPKRRASPSPPPKRRVSHSP 639

Query: 1059 -----GSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPP 1113
                  S +T  RS  +    RK +  ++++ E   P P  R +  P    A   + SPP
Sbjct: 640  PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR-APQTSSSPP 698

Query: 1114 PVTTSSSKDEEEEE 1127
            PV   +S   +  +
Sbjct: 699  PVRRGASSSPQRRQ 712



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 17/141 (12%)

Query: 1000 KSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPG 1059
            +S+     P A  P     AP   V+    S N    +     KSP P P PPR S   G
Sbjct: 751  RSVSGSPEPAAKKP----PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806

Query: 1060 SGLTTTRSGDVVY----------TGRKENITAKASSEDAGPSPQTRATKYPA-EEPASAW 1108
             G    +  D  +            +KE   A A++    P+    AT   A EEP +A 
Sbjct: 807  GGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAA- 865

Query: 1109 TPSPPPVTTSSSKDEEEEEEE 1129
             P P   T S ++D  ++ E+
Sbjct: 866  -PEPKKETESEAEDNLDDLEK 885



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 92/409 (22%), Positives = 134/409 (32%), Gaps = 93/409 (22%)

Query: 2   EENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNS-RGSVSKSS 60
           +E E +K  P       R + + + +      SP     RR     S   S R   S   
Sbjct: 267 KEKEKEKTRP-------RSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR 319

Query: 61  RNIPRRHT----LGGP--------------RSSKEILGMQTSEMDRKREAFLEHLKQKYP 102
           R  PRR T    +  P              RSS  + G  +S    +  +      +K P
Sbjct: 320 RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS----PPKKPP 375

Query: 103 HHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSR 162
              S+      RL      P+  H P PP+   P    S               PTP  +
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS---------------PTP-QQ 419

Query: 163 GSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQL 222
            +RTR S       + +  R+ G +    G E ++   P     A   R + +S   +  
Sbjct: 420 SNRTRKS-----RVSVSPGRTSGKVTKHKGTEKRESPSP-----APKPRKVELSESEEDK 469

Query: 223 TMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDP--AHAFN--------H 272
             KM  + SV      + R  Y   N   +    S     ++ P  +H  N        H
Sbjct: 470 GGKMAAADSV------QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH 523

Query: 273 TP-KTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPP-----STPVPHSMPPS 326
           +P ++ +   R +++    RG    +P P  T       P  PP      TP P    PS
Sbjct: 524 SPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS 583

Query: 327 PSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKP 375
           P             P     P  R  S P+ R  SPSP    +RR   P
Sbjct: 584 P-------------PPRRRSPSPRRYSPPIQRRYSPSPPP--KRRTASP 617


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 79/339 (23%), Positives = 122/339 (35%), Gaps = 52/339 (15%)

Query: 1625 IARSQPEDT--PENTVRRQEQPSIESTSPISRTD---EIRKNTYRTLDSLEQTIKQLENT 1679
            +++S+  DT   E  +  +   +I      SRTD   E + +      S    +  + + 
Sbjct: 110  LSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSV 169

Query: 1680 ISEMSPKALVDTSCSSNRDSVASSSHIAQE-ASPRPLLVPDEGPTALEPPTSIPSASRKG 1738
            +++ +P  L+  S +S  ++      + +E   P  ++ P   P   +PP  IP     G
Sbjct: 170  VNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP---PLQQQPPKPIPKQQGPG 226

Query: 1739 -----SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQ-----------YRQANGS 1782
                   G P++     P   K++P     PG    +Q P Q            R A+  
Sbjct: 227  RDPLQQDGTPKSISSQQPEKIKSQP-----PGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 1783 AKKSGGDFKPTS--PSLPA-SKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNP 1839
              K     +  S  PSLP+ SK P   P+ GK  +       S   P  P  +PS  + P
Sbjct: 282  QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341

Query: 1840 LSPQTG-------------PPAH--SASLIPSVSNGSLKFQSLTHTGKG----HHLSFSP 1880
            L+ Q G             PPA     +  P+   GS K  S     K       +  +P
Sbjct: 342  LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP 401

Query: 1881 QSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTP 1919
              Q G A PP     +P   A    L   AK      TP
Sbjct: 402  AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 192/1008 (19%), Positives = 347/1008 (34%), Gaps = 131/1008 (12%)

Query: 897  SQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSV 956
            SQ S  +    Q  PH  S P  P +       SQ P S   P +         + I  V
Sbjct: 940  SQASNLISTAGQPGPHSQSGPGAPMKQAPA--PSQPPTSQGPPKSTGQAPPAPAKSI-PV 996

Query: 957  SAKNRAVSIEKAEKKWEE----KRQNLDHYNG--KEFEKLLEEAQANIMKSIPNLEMPPA 1010
              + +A + EK E K E+    KR   +      K+ + L  E Q  ++ +   LE  P 
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT--KLEKSPK 1054

Query: 1011 TGPLPRGDAPVDKVEL---SEDSPNSEQDLE------KLGGKSPPPPPPPPRRSYLPGSG 1061
                P    P+ K EL   S+D PN     E       L G +P P     +        
Sbjct: 1055 ----PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1110

Query: 1062 LTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSK 1121
                 SG +           K     +GP    +A+  P    +S+   + PP      K
Sbjct: 1111 TQRAISGQL-------GDIRKMPPAPSGP----KASPMPVPTESSSQKTAVPPQVKLVKK 1159

Query: 1122 DEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGA---TVPPKEKK 1178
             E+E + E +K++ E +  +  S   +      +  + +S ++  ++ A     P  E+K
Sbjct: 1160 QEQEVKTEAEKVILE-KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEK 1218

Query: 1179 NLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTE 1238
             L    E +R      E  P +E +K T     P D  K     + S  +  +    K++
Sbjct: 1219 KLIPEEEKIRSE----EKKPLLEEKKPT-----PED-KKLLPEAKTSAPEEQKHDLLKSQ 1268

Query: 1239 IIMKENSISNMSLLRDSRNYSQETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTEN 1298
            + + E  +      +  +   Q               L  E +K +K    Q   P T  
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328

Query: 1299 QTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQV-VLRPKEARH 1357
                    KE  ++  DK   SS  +              + I++  G++  L P + + 
Sbjct: 1329 PD-QVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKD 1387

Query: 1358 ANVNPNEDGESSSSSPTEEN--AATDNIAFMITETTVQVLS------SGEVHDIVSQKGE 1409
                  +D  S  SSP+  +  A  ++    I E     L+        + H++  ++ +
Sbjct: 1388 ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPK 1447

Query: 1410 DIQ-TVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECD 1468
            D + T ++    E+T  +E           +++      D   DI S+ K      E  D
Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQ-----EERKDTFKKDSQQDIPSS-KDHKEKSEFVD 1501

Query: 1469 EELERMMMEEKIEEEEEEENGDSVVQNNNT---SQMSHKKVAPGNLRTGQQVETKSQPHS 1525
            +   R    + +EE  E EN     +   T   S  S +     +  +G++ +   +   
Sbjct: 1502 DITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561

Query: 1526 LATETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAAL 1585
              +   +  G E +    N+   + S     K E+         K K K    K +    
Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKKEET--------KGKGKITAGKHRRLTR 1613

Query: 1586 TQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPED---TPENTVRRQE 1642
              +       G++         +E+D    +  E K  E    + E+   T    +RR +
Sbjct: 1614 KSSTSIDEDAGRRHSW-----HDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFK 1668

Query: 1643 QPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVAS 1702
              +IE  S I+       + Y    S ++T    +    E+  ++L D+    +R   +S
Sbjct: 1669 --TIELNSTIA-------DKYSAESSQKKTSLYFDEE-PELEMESLTDSPEDRSRGEGSS 1718

Query: 1703 SSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRP---- 1758
            S H +          P   PT++        +S     G  +  R      A++RP    
Sbjct: 1719 SLHASS-------FTPGTSPTSVSSLDEDSDSSPSHKKGESKQQR-----KARHRPHGPL 1766

Query: 1759 -GTLDKPGKQSKLQDPR------------QYRQANGSAKKSGGD-------FKPTSPSLP 1798
              T++   ++ +L++              + +Q   S+KKS  D        +   P  P
Sbjct: 1767 LPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP 1826

Query: 1799 ASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGP 1846
             S +  +  +S       ++  +  +  +     PSI S+P   +  P
Sbjct: 1827 PSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISP 1874



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 167/789 (21%), Positives = 278/789 (35%), Gaps = 130/789 (16%)

Query: 1105 ASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVK 1164
            AS++TP   P T+ SS DE+ +     K   E +  +K        +    P+  DS  +
Sbjct: 1722 ASSFTPGTSP-TSVSSLDEDSDSSPSHK-KGESKQQRKARH---RPHGPLLPTIEDSSEE 1776

Query: 1165 DTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMEN 1224
            +         KE++      +  RKS  +     + E +     A R  + PK      +
Sbjct: 1777 EELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELR-----AQRRRERPKTPPSNLS 1831

Query: 1225 SISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQETVPKASFGFSGISPLED-EINKG 1283
             I DAS T E +    M+E       L R S +    ++     GF  ISP +  E+ K 
Sbjct: 1832 PIEDASPTEELRQAAEMEE-------LHRSSCSEYSPSIESDPEGFE-ISPEKIIEVQKV 1883

Query: 1284 SKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITT 1343
             K+         T+ Q++       M+K+ + K  + S   + E  +H  KT   +    
Sbjct: 1884 YKLPTAVSLYSPTDEQSI-------MQKEGSQKA-LKSAEEMYEEMMH--KTHKYKAFPA 1933

Query: 1344 DFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDI 1403
               +  +  KE  +  +   ED    S      N + D       E         E +  
Sbjct: 1934 ANERDEVFEKEPLYGGMLI-EDYIYESLVEDTYNGSVDGSLLTRQE---------EENGF 1983

Query: 1404 VSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTI 1463
            + QKG + Q + +  +    P Q+ TD +     L+    ++  +   DI S+    S I
Sbjct: 1984 MQQKGRE-QKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQE---DIVSS----SFI 2035

Query: 1464 FEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQP 1523
              E  E ++   M    EEE +  + D+  +     Q    ++ PG+             
Sbjct: 2036 IPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQM--QLTPGS------------- 2080

Query: 1524 HSLATETRNPGGQEMNRT--ELNKFSHVDSPNSECKGEDATDDQFES----PKKKFKFKF 1577
                + T+ P G++M  +  + ++       +S   G   TD    +    P  K    F
Sbjct: 2081 ----SPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHF 2136

Query: 1578 PKKQLAA--LTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPE 1635
              +++    +T   R   +       ++ Y E  E  T                P DTP 
Sbjct: 2137 STEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESAT-------------SVPPSDTPS 2183

Query: 1636 NTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVD----T 1691
             T       + +S+SPI+  D I       +D + +     E + S   P +++D     
Sbjct: 2184 LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEI 2243

Query: 1692 SCSSNR----DSVASSSHIAQEASP------RPLLVPDEGPTALEPPTSI------PSAS 1735
            S S +R    D  AS+ HI    S         ++   EGP A    T +      P   
Sbjct: 2244 SVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKK 2303

Query: 1736 RKGSSG------APQTSRMPVPMSAKNRPGTLDK------PGKQSKLQDPRQYRQANGSA 1783
             K  +G        +  R    + A+    +L +      P     L    Q      ++
Sbjct: 2304 AKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTS 2363

Query: 1784 KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLP-----SSSGDSSNLPNPPATKPSIASN 1838
             ++ G  K      PAS++P+ SPS     + P     SSS D S  P PP   P     
Sbjct: 2364 GETFGQEK------PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP 2417

Query: 1839 PLSPQTGPP 1847
            P  P   PP
Sbjct: 2418 PPPPPPPPP 2426



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 54/203 (26%), Positives = 71/203 (34%), Gaps = 29/203 (14%)

Query: 1721 GPTAL-EPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGK-----QSKLQDPR 1774
            GP AL +PP    + +++     P T ++  P     +PG L  P K     ++ +Q P 
Sbjct: 387  GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG-LQSPAKAPGPTKTPVQQPG 445

Query: 1775 QYR---QANGSAKKSGGDFKPTSPSL---------PASKIPALSPSSGKSSSLPSSSGDS 1822
              +   Q  G  K S     PT P           P    PA  P     S+ P S    
Sbjct: 446  PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 1823 SNLPNPPATKPSIASNPLSPQTGPPAHS-ASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQ 1881
            S  P P    P+  S      T PP+    S  PS    S    S   + K       P 
Sbjct: 506  STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK-------PV 558

Query: 1882 SQNGRAPP--PLSFSSSPPSPAS 1902
            SQ G   P  P + S S   P S
Sbjct: 559  SQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 16/134 (11%)

Query: 1707 AQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPV--PMSAK---NRPGTL 1761
            AQ+A P        GPT  +PP+ +P  + K     P  ++ P   P SAK    +PG+ 
Sbjct: 451  AQQAGPGKTSAQQTGPT--KPPSQLPGPA-KPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 1762 DKPGKQSKLQDPRQYR--------QANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSS 1813
              P +Q     P   +        Q  GSAK S     P  PS   S  P     SGK  
Sbjct: 508  KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567

Query: 1814 SLPSSSGDSSNLPN 1827
              P+ S  +   P+
Sbjct: 568  QPPTVSPSAKQPPS 581



 Score = 38.5 bits (88), Expect = 0.065
 Identities = 179/922 (19%), Positives = 309/922 (33%), Gaps = 162/922 (17%)

Query: 891  PVVIQPSQHSVALLNPAQNLPHVASS---PAVPQEATSTLQMSQAPQSPQIPMNGSAMQS 947
            P+V QP+ H        Q  P  A S   PA P+E +   +  +AP +   P     ++ 
Sbjct: 705  PLVKQPTLHGSPSAKAKQ--PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762

Query: 948  LFIEEIHSVSAKNRA-VSIEKAEKKWEEKR----QNLDHYNGKEFEKLLEEAQANIMKSI 1002
               + + S SA  +  +   K + + EEK     +       + F    E+      K+I
Sbjct: 763  T-TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821

Query: 1003 PN------LEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSP----PPPPPPP 1052
            P       +   P      +G   VD V+  E+   ++  +       P     P PP P
Sbjct: 822  PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881

Query: 1053 RRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSP 1112
            R    P +G T                     +    P PQ ++ ++     +    P  
Sbjct: 882  R----PTAGQTVP-------------------TPQQSPKPQEQSRRFSLNLGSITDAPKS 918

Query: 1113 PPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATV 1172
             P T   +            +  +L  F    F    SN  +   +   H   ++SG   
Sbjct: 919  QPTTPQET------------VTGKLFGFGASIFSQA-SNLISTAGQPGPH---SQSGPGA 962

Query: 1173 PPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRT 1232
            P K+             S      GP       +TG   P+ P K     + + + A+  
Sbjct: 963  PMKQAP---------APSQPPTSQGPPK-----STGQAPPA-PAKSIPVKKETKAPAAEK 1007

Query: 1233 SEYKTE---IIMKENSISNMSLLRDSRNYSQET--------VPKASFGFSGISPLEDEIN 1281
             E K E    + +  +      ++DS++ + E         + K+    S     + E+N
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067

Query: 1282 KGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVH-DFKTEDQEV 1340
             GSK                N+    E + Q  + C  +    LTE         + Q  
Sbjct: 1068 IGSK-------------DPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA 1114

Query: 1341 ITTDFGQVVLRPKEARHANVNPNEDGESSSSSPT-----------EENAATDNIAFMITE 1389
            I+   G +   P        +P      SSS  T           +E         +I E
Sbjct: 1115 ISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174

Query: 1390 TTVQVLSSGEVHDIVS--QKGED--IQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVII 1445
               + LS  ++  +V+  QK E+  ++     A +E  P  E           +KK    
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE-----------EKK---- 1219

Query: 1446 IFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKK 1505
            +  E   IRS  K+     ++   E ++++ E K    EE+++     Q     +    +
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279

Query: 1506 VAPGNLRTGQQVETKSQ------PHSLATE---TRNPGGQEMNRTELNKFSHVDSPNSEC 1556
            VAP  ++ G+Q +TK +      P SL  E   T     ++       K   V+    + 
Sbjct: 1280 VAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKT 1339

Query: 1557 KGEDATDDQFESPKKK---------FKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEE 1607
            + ED   D   S + K         +        L  +   I T  K   K L+   + +
Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQ 1399

Query: 1608 EEEDGTLKQ--HKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRT 1665
            E    +       E+    I  +Q     +    ++ QP     SP    D+  + T   
Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP--HEVSPEQPKDQ--EKTQSL 1455

Query: 1666 LDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTAL 1725
             ++LE TI + E   S+   K   DT    ++  + SS    +++        D+  T  
Sbjct: 1456 SETLEITISEEEIKESQEERK---DTFKKDSQQDIPSSKDHKEKSE-----FVDDITTRR 1507

Query: 1726 EPPTSIPSASRKGSSGAPQTSR 1747
            EP  S+  +S   +S  PQ  R
Sbjct: 1508 EPYDSVEESSESENSPVPQRKR 1529



 Score = 38.1 bits (87), Expect = 0.084
 Identities = 77/375 (20%), Positives = 127/375 (33%), Gaps = 68/375 (18%)

Query: 1582 LAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQ 1641
            LA +  + +   KT   T    V +   +       K+A   +     PE  P+      
Sbjct: 650  LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE--PKKPPPLV 707

Query: 1642 EQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVA 1701
            +QP++   SP ++  +  +      DSL +     E ++     KA V          V 
Sbjct: 708  KQPTLHG-SPSAKAKQPPE-----ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761

Query: 1702 SSSHI--AQEASPRPLLVPDEGPTALEPPTSIP--SASRKGSSGAPQTSRMPVPMSAKNR 1757
             ++ +  +  A+ +P +   +  +  E  T+ P  + S K S   P T     P  +K  
Sbjct: 762  PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821

Query: 1758 PGTLDKPGKQSKL-QDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLP 1816
            P    +P   SK+   P    ++ G  +             P  K      +  K S  P
Sbjct: 822  P----RPASDSKIISHPGPSSESKGQKQVD-----------PVQKKEEPKKAQTKMSPKP 866

Query: 1817 SSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSL----KFQSLTH--- 1869
             +       P PP  +P+      +PQ  P     S   S++ GS+    K Q  T    
Sbjct: 867  DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQET 926

Query: 1870 -TGK----------------------GHHLSFSPQSQNGRAP----------PPLSFSSS 1896
             TGK                      G H    P +   +AP          PP S   +
Sbjct: 927  VTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA 986

Query: 1897 PPSPASSVSLNQGAK 1911
            PP+PA S+ + +  K
Sbjct: 987  PPAPAKSIPVKKETK 1001



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 56/231 (24%), Positives = 73/231 (31%), Gaps = 20/231 (8%)

Query: 1718 PDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQ--DPRQ 1775
            P   P     P +  + S K SS  P    +  P      P     P K    Q   P+ 
Sbjct: 361  PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420

Query: 1776 YRQANG--SAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSS-SGDSSNLPNPPATK 1832
              Q  G  S  K+ G  K         KIPA     GK+S+  +  +   S LP  PA  
Sbjct: 421  LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG-PAKP 479

Query: 1833 PSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLS 1892
            P     P  P    P  +    PS   GS K        +      SPQ      PP   
Sbjct: 480  PPQQPGPAKPPPQQPGSAKP--PSQQPGSTK----PPPQQPGPAKPSPQQPGSTKPPSQQ 533

Query: 1893 FSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1943
              S+ PS          A+ +        T   +Q GS     P T   ++
Sbjct: 534  PGSAKPSAQQPSPAKPSAQQS--------TKPVSQTGSGKPLQPPTVSPSA 576



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 53/255 (20%), Positives = 80/255 (31%), Gaps = 23/255 (9%)

Query: 886  HAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAM 945
            H +S P   +P      L  P    P     P  P   T        P  P     GS  
Sbjct: 321  HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 946  QSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNL 1005
             S    E     A  +   + K   +     +      G       +    +  K+    
Sbjct: 381  PS---SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 1006 EMP---PATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPP----PPPRRSYLP 1058
            + P   P  G +P   A   K    +  P           K PP  P    PPP++   P
Sbjct: 438  KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ---P 494

Query: 1059 GSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPS---PPPV 1115
            GS    ++         ++   AK S +  G      +TK P+++P SA  PS   P P 
Sbjct: 495  GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG------STKPPSQQPGSA-KPSAQQPSPA 547

Query: 1116 TTSSSKDEEEEEEEG 1130
              S+ +  +   + G
Sbjct: 548  KPSAQQSTKPVSQTG 562



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 10/80 (12%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSL 354
           P + +PGST  PP     + PS   P S  P PS+ P     S   P  A  P  + S+ 
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAK-PSAQQSTK 556

Query: 355 PVS-----RPISP---SPSA 366
           PVS     +P+ P   SPSA
Sbjct: 557 PVSQTGSGKPLQPPTVSPSA 576



 Score = 31.6 bits (70), Expect = 7.9
 Identities = 52/254 (20%), Positives = 91/254 (35%), Gaps = 33/254 (12%)

Query: 1702 SSSHIAQEASPRPLLVPDEGPTALEPPT-SIPSA------SRKGSSGAPQTSRMPVPMSA 1754
            S+  ++Q  S +PL  P   P+A +PP+  +P        + +     P+ +        
Sbjct: 554  STKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTEC 613

Query: 1755 KNRPGTLDKPGKQSKLQDPRQYRQANGSAKKS-GGDFKPTSPSLPASKIPALSPSSGKSS 1813
            +    +L        L + +++   N   K++ GGD  P  PS P  K+        K++
Sbjct: 614  QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV-PSSPQPKL--------KTA 664

Query: 1814 SLPSSSGDSSNLPNPPATKPSIASNPL-------SPQTGPPAHSASLIPSVSNGSLK--- 1863
             + ++S  S + P P  T P   + P         P+  PP      +    +   K   
Sbjct: 665  PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 1864 -FQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLT 1922
               SL+        S    S+  +AP        P     +  L   +  T     P + 
Sbjct: 725  EADSLSKPAPPKEPSV--PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT---KPDIP 779

Query: 1923 SYKAQNGSSSKATP 1936
            S K Q+ +  K TP
Sbjct: 780  SSKVQSQAEEKTTP 793


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 79/339 (23%), Positives = 122/339 (35%), Gaps = 52/339 (15%)

Query: 1625 IARSQPEDT--PENTVRRQEQPSIESTSPISRTD---EIRKNTYRTLDSLEQTIKQLENT 1679
            +++S+  DT   E  +  +   +I      SRTD   E + +      S    +  + + 
Sbjct: 110  LSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSV 169

Query: 1680 ISEMSPKALVDTSCSSNRDSVASSSHIAQE-ASPRPLLVPDEGPTALEPPTSIPSASRKG 1738
            +++ +P  L+  S +S  ++      + +E   P  ++ P   P   +PP  IP     G
Sbjct: 170  VNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP---PLQQQPPKPIPKQQGPG 226

Query: 1739 -----SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQ-----------YRQANGS 1782
                   G P++     P   K++P     PG    +Q P Q            R A+  
Sbjct: 227  RDPLQQDGTPKSISSQQPEKIKSQP-----PGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 1783 AKKSGGDFKPTS--PSLPA-SKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNP 1839
              K     +  S  PSLP+ SK P   P+ GK  +       S   P  P  +PS  + P
Sbjct: 282  QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341

Query: 1840 LSPQTG-------------PPAH--SASLIPSVSNGSLKFQSLTHTGKG----HHLSFSP 1880
            L+ Q G             PPA     +  P+   GS K  S     K       +  +P
Sbjct: 342  LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP 401

Query: 1881 QSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTP 1919
              Q G A PP     +P   A    L   AK      TP
Sbjct: 402  AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 192/1008 (19%), Positives = 347/1008 (34%), Gaps = 131/1008 (12%)

Query: 897  SQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSV 956
            SQ S  +    Q  PH  S P  P +       SQ P S   P +         + I  V
Sbjct: 940  SQASNLISTAGQPGPHSQSGPGAPMKQAPA--PSQPPTSQGPPKSTGQAPPAPAKSI-PV 996

Query: 957  SAKNRAVSIEKAEKKWEE----KRQNLDHYNG--KEFEKLLEEAQANIMKSIPNLEMPPA 1010
              + +A + EK E K E+    KR   +      K+ + L  E Q  ++ +   LE  P 
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT--KLEKSPK 1054

Query: 1011 TGPLPRGDAPVDKVEL---SEDSPNSEQDLE------KLGGKSPPPPPPPPRRSYLPGSG 1061
                P    P+ K EL   S+D PN     E       L G +P P     +        
Sbjct: 1055 ----PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1110

Query: 1062 LTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSK 1121
                 SG +           K     +GP    +A+  P    +S+   + PP      K
Sbjct: 1111 TQRAISGQL-------GDIRKMPPAPSGP----KASPMPVPTESSSQKTAVPPQVKLVKK 1159

Query: 1122 DEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGA---TVPPKEKK 1178
             E+E + E +K++ E +  +  S   +      +  + +S ++  ++ A     P  E+K
Sbjct: 1160 QEQEVKTEAEKVILE-KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEK 1218

Query: 1179 NLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTE 1238
             L    E +R      E  P +E +K T     P D  K     + S  +  +    K++
Sbjct: 1219 KLIPEEEKIRSE----EKKPLLEEKKPT-----PED-KKLLPEAKTSAPEEQKHDLLKSQ 1268

Query: 1239 IIMKENSISNMSLLRDSRNYSQETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTEN 1298
            + + E  +      +  +   Q               L  E +K +K    Q   P T  
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328

Query: 1299 QTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQV-VLRPKEARH 1357
                    KE  ++  DK   SS  +              + I++  G++  L P + + 
Sbjct: 1329 PD-QVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKD 1387

Query: 1358 ANVNPNEDGESSSSSPTEEN--AATDNIAFMITETTVQVLS------SGEVHDIVSQKGE 1409
                  +D  S  SSP+  +  A  ++    I E     L+        + H++  ++ +
Sbjct: 1388 ILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPK 1447

Query: 1410 DIQ-TVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECD 1468
            D + T ++    E+T  +E           +++      D   DI S+ K      E  D
Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQ-----EERKDTFKKDSQQDIPSS-KDHKEKSEFVD 1501

Query: 1469 EELERMMMEEKIEEEEEEENGDSVVQNNNT---SQMSHKKVAPGNLRTGQQVETKSQPHS 1525
            +   R    + +EE  E EN     +   T   S  S +     +  +G++ +   +   
Sbjct: 1502 DITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561

Query: 1526 LATETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAAL 1585
              +   +  G E +    N+   + S     K E+         K K K    K +    
Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKKEET--------KGKGKITAGKHRRLTR 1613

Query: 1586 TQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPED---TPENTVRRQE 1642
              +       G++         +E+D    +  E K  E    + E+   T    +RR +
Sbjct: 1614 KSSTSIDEDAGRRHSW-----HDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFK 1668

Query: 1643 QPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVAS 1702
              +IE  S I+       + Y    S ++T    +    E+  ++L D+    +R   +S
Sbjct: 1669 --TIELNSTIA-------DKYSAESSQKKTSLYFDEE-PELEMESLTDSPEDRSRGEGSS 1718

Query: 1703 SSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRP---- 1758
            S H +          P   PT++        +S     G  +  R      A++RP    
Sbjct: 1719 SLHASS-------FTPGTSPTSVSSLDEDSDSSPSHKKGESKQQR-----KARHRPHGPL 1766

Query: 1759 -GTLDKPGKQSKLQDPR------------QYRQANGSAKKSGGD-------FKPTSPSLP 1798
              T++   ++ +L++              + +Q   S+KKS  D        +   P  P
Sbjct: 1767 LPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP 1826

Query: 1799 ASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGP 1846
             S +  +  +S       ++  +  +  +     PSI S+P   +  P
Sbjct: 1827 PSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISP 1874



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 167/789 (21%), Positives = 278/789 (35%), Gaps = 130/789 (16%)

Query: 1105 ASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVK 1164
            AS++TP   P T+ SS DE+ +     K   E +  +K        +    P+  DS  +
Sbjct: 1722 ASSFTPGTSP-TSVSSLDEDSDSSPSHK-KGESKQQRKARH---RPHGPLLPTIEDSSEE 1776

Query: 1165 DTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMEN 1224
            +         KE++      +  RKS  +     + E +     A R  + PK      +
Sbjct: 1777 EELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELR-----AQRRRERPKTPPSNLS 1831

Query: 1225 SISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQETVPKASFGFSGISPLED-EINKG 1283
             I DAS T E +    M+E       L R S +    ++     GF  ISP +  E+ K 
Sbjct: 1832 PIEDASPTEELRQAAEMEE-------LHRSSCSEYSPSIESDPEGFE-ISPEKIIEVQKV 1883

Query: 1284 SKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITT 1343
             K+         T+ Q++       M+K+ + K  + S   + E  +H  KT   +    
Sbjct: 1884 YKLPTAVSLYSPTDEQSI-------MQKEGSQKA-LKSAEEMYEEMMH--KTHKYKAFPA 1933

Query: 1344 DFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDI 1403
               +  +  KE  +  +   ED    S      N + D       E         E +  
Sbjct: 1934 ANERDEVFEKEPLYGGMLI-EDYIYESLVEDTYNGSVDGSLLTRQE---------EENGF 1983

Query: 1404 VSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTI 1463
            + QKG + Q + +  +    P Q+ TD +     L+    ++  +   DI S+    S I
Sbjct: 1984 MQQKGRE-QKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQE---DIVSS----SFI 2035

Query: 1464 FEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQP 1523
              E  E ++   M    EEE +  + D+  +     Q    ++ PG+             
Sbjct: 2036 IPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQM--QLTPGS------------- 2080

Query: 1524 HSLATETRNPGGQEMNRT--ELNKFSHVDSPNSECKGEDATDDQFES----PKKKFKFKF 1577
                + T+ P G++M  +  + ++       +S   G   TD    +    P  K    F
Sbjct: 2081 ----SPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHF 2136

Query: 1578 PKKQLAA--LTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPE 1635
              +++    +T   R   +       ++ Y E  E  T                P DTP 
Sbjct: 2137 STEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESAT-------------SVPPSDTPS 2183

Query: 1636 NTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVD----T 1691
             T       + +S+SPI+  D I       +D + +     E + S   P +++D     
Sbjct: 2184 LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEI 2243

Query: 1692 SCSSNR----DSVASSSHIAQEASP------RPLLVPDEGPTALEPPTSI------PSAS 1735
            S S +R    D  AS+ HI    S         ++   EGP A    T +      P   
Sbjct: 2244 SVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKK 2303

Query: 1736 RKGSSG------APQTSRMPVPMSAKNRPGTLDK------PGKQSKLQDPRQYRQANGSA 1783
             K  +G        +  R    + A+    +L +      P     L    Q      ++
Sbjct: 2304 AKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTS 2363

Query: 1784 KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLP-----SSSGDSSNLPNPPATKPSIASN 1838
             ++ G  K      PAS++P+ SPS     + P     SSS D S  P PP   P     
Sbjct: 2364 GETFGQEK------PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP 2417

Query: 1839 PLSPQTGPP 1847
            P  P   PP
Sbjct: 2418 PPPPPPPPP 2426



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 54/203 (26%), Positives = 71/203 (34%), Gaps = 29/203 (14%)

Query: 1721 GPTAL-EPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGK-----QSKLQDPR 1774
            GP AL +PP    + +++     P T ++  P     +PG L  P K     ++ +Q P 
Sbjct: 387  GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG-LQSPAKAPGPTKTPVQQPG 445

Query: 1775 QYR---QANGSAKKSGGDFKPTSPSL---------PASKIPALSPSSGKSSSLPSSSGDS 1822
              +   Q  G  K S     PT P           P    PA  P     S+ P S    
Sbjct: 446  PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 1823 SNLPNPPATKPSIASNPLSPQTGPPAHS-ASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQ 1881
            S  P P    P+  S      T PP+    S  PS    S    S   + K       P 
Sbjct: 506  STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK-------PV 558

Query: 1882 SQNGRAPP--PLSFSSSPPSPAS 1902
            SQ G   P  P + S S   P S
Sbjct: 559  SQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 16/134 (11%)

Query: 1707 AQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPV--PMSAK---NRPGTL 1761
            AQ+A P        GPT  +PP+ +P  + K     P  ++ P   P SAK    +PG+ 
Sbjct: 451  AQQAGPGKTSAQQTGPT--KPPSQLPGPA-KPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 1762 DKPGKQSKLQDPRQYR--------QANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSS 1813
              P +Q     P   +        Q  GSAK S     P  PS   S  P     SGK  
Sbjct: 508  KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567

Query: 1814 SLPSSSGDSSNLPN 1827
              P+ S  +   P+
Sbjct: 568  QPPTVSPSAKQPPS 581



 Score = 38.5 bits (88), Expect = 0.065
 Identities = 179/922 (19%), Positives = 309/922 (33%), Gaps = 162/922 (17%)

Query: 891  PVVIQPSQHSVALLNPAQNLPHVASS---PAVPQEATSTLQMSQAPQSPQIPMNGSAMQS 947
            P+V QP+ H        Q  P  A S   PA P+E +   +  +AP +   P     ++ 
Sbjct: 705  PLVKQPTLHGSPSAKAKQ--PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762

Query: 948  LFIEEIHSVSAKNRA-VSIEKAEKKWEEKR----QNLDHYNGKEFEKLLEEAQANIMKSI 1002
               + + S SA  +  +   K + + EEK     +       + F    E+      K+I
Sbjct: 763  T-TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821

Query: 1003 PN------LEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSP----PPPPPPP 1052
            P       +   P      +G   VD V+  E+   ++  +       P     P PP P
Sbjct: 822  PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881

Query: 1053 RRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSP 1112
            R    P +G T                     +    P PQ ++ ++     +    P  
Sbjct: 882  R----PTAGQTVP-------------------TPQQSPKPQEQSRRFSLNLGSITDAPKS 918

Query: 1113 PPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATV 1172
             P T   +            +  +L  F    F    SN  +   +   H   ++SG   
Sbjct: 919  QPTTPQET------------VTGKLFGFGASIFSQA-SNLISTAGQPGPH---SQSGPGA 962

Query: 1173 PPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRT 1232
            P K+             S      GP       +TG   P+ P K     + + + A+  
Sbjct: 963  PMKQAP---------APSQPPTSQGPPK-----STGQAPPA-PAKSIPVKKETKAPAAEK 1007

Query: 1233 SEYKTE---IIMKENSISNMSLLRDSRNYSQET--------VPKASFGFSGISPLEDEIN 1281
             E K E    + +  +      ++DS++ + E         + K+    S     + E+N
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067

Query: 1282 KGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHTRLTESSVH-DFKTEDQEV 1340
             GSK                N+    E + Q  + C  +    LTE         + Q  
Sbjct: 1068 IGSK-------------DPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA 1114

Query: 1341 ITTDFGQVVLRPKEARHANVNPNEDGESSSSSPT-----------EENAATDNIAFMITE 1389
            I+   G +   P        +P      SSS  T           +E         +I E
Sbjct: 1115 ISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174

Query: 1390 TTVQVLSSGEVHDIVS--QKGED--IQTVNIDARKEMTPRQEGTDNEDPVVCLDKKPVII 1445
               + LS  ++  +V+  QK E+  ++     A +E  P  E           +KK    
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE-----------EKK---- 1219

Query: 1446 IFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKK 1505
            +  E   IRS  K+     ++   E ++++ E K    EE+++     Q     +    +
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279

Query: 1506 VAPGNLRTGQQVETKSQ------PHSLATE---TRNPGGQEMNRTELNKFSHVDSPNSEC 1556
            VAP  ++ G+Q +TK +      P SL  E   T     ++       K   V+    + 
Sbjct: 1280 VAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKT 1339

Query: 1557 KGEDATDDQFESPKKK---------FKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEE 1607
            + ED   D   S + K         +        L  +   I T  K   K L+   + +
Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQ 1399

Query: 1608 EEEDGTLKQ--HKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRT 1665
            E    +       E+    I  +Q     +    ++ QP     SP    D+  + T   
Sbjct: 1400 ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP--HEVSPEQPKDQ--EKTQSL 1455

Query: 1666 LDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTAL 1725
             ++LE TI + E   S+   K   DT    ++  + SS    +++        D+  T  
Sbjct: 1456 SETLEITISEEEIKESQEERK---DTFKKDSQQDIPSSKDHKEKSE-----FVDDITTRR 1507

Query: 1726 EPPTSIPSASRKGSSGAPQTSR 1747
            EP  S+  +S   +S  PQ  R
Sbjct: 1508 EPYDSVEESSESENSPVPQRKR 1529



 Score = 38.1 bits (87), Expect = 0.084
 Identities = 77/375 (20%), Positives = 127/375 (33%), Gaps = 68/375 (18%)

Query: 1582 LAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQ 1641
            LA +  + +   KT   T    V +   +       K+A   +     PE  P+      
Sbjct: 650  LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE--PKKPPPLV 707

Query: 1642 EQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVA 1701
            +QP++   SP ++  +  +      DSL +     E ++     KA V          V 
Sbjct: 708  KQPTLHG-SPSAKAKQPPE-----ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761

Query: 1702 SSSHI--AQEASPRPLLVPDEGPTALEPPTSIP--SASRKGSSGAPQTSRMPVPMSAKNR 1757
             ++ +  +  A+ +P +   +  +  E  T+ P  + S K S   P T     P  +K  
Sbjct: 762  PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821

Query: 1758 PGTLDKPGKQSKL-QDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLP 1816
            P    +P   SK+   P    ++ G  +             P  K      +  K S  P
Sbjct: 822  P----RPASDSKIISHPGPSSESKGQKQVD-----------PVQKKEEPKKAQTKMSPKP 866

Query: 1817 SSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSL----KFQSLTH--- 1869
             +       P PP  +P+      +PQ  P     S   S++ GS+    K Q  T    
Sbjct: 867  DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQET 926

Query: 1870 -TGK----------------------GHHLSFSPQSQNGRAP----------PPLSFSSS 1896
             TGK                      G H    P +   +AP          PP S   +
Sbjct: 927  VTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA 986

Query: 1897 PPSPASSVSLNQGAK 1911
            PP+PA S+ + +  K
Sbjct: 987  PPAPAKSIPVKKETK 1001



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 56/231 (24%), Positives = 73/231 (31%), Gaps = 20/231 (8%)

Query: 1718 PDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQ--DPRQ 1775
            P   P     P +  + S K SS  P    +  P      P     P K    Q   P+ 
Sbjct: 361  PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420

Query: 1776 YRQANG--SAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSS-SGDSSNLPNPPATK 1832
              Q  G  S  K+ G  K         KIPA     GK+S+  +  +   S LP  PA  
Sbjct: 421  LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG-PAKP 479

Query: 1833 PSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLS 1892
            P     P  P    P  +    PS   GS K        +      SPQ      PP   
Sbjct: 480  PPQQPGPAKPPPQQPGSAKP--PSQQPGSTK----PPPQQPGPAKPSPQQPGSTKPPSQQ 533

Query: 1893 FSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1943
              S+ PS          A+ +        T   +Q GS     P T   ++
Sbjct: 534  PGSAKPSAQQPSPAKPSAQQS--------TKPVSQTGSGKPLQPPTVSPSA 576



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 53/255 (20%), Positives = 80/255 (31%), Gaps = 23/255 (9%)

Query: 886  HAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAM 945
            H +S P   +P      L  P    P     P  P   T        P  P     GS  
Sbjct: 321  HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 946  QSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNL 1005
             S    E     A  +   + K   +     +      G       +    +  K+    
Sbjct: 381  PS---SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 1006 EMP---PATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPP----PPPRRSYLP 1058
            + P   P  G +P   A   K    +  P           K PP  P    PPP++   P
Sbjct: 438  KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ---P 494

Query: 1059 GSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPS---PPPV 1115
            GS    ++         ++   AK S +  G      +TK P+++P SA  PS   P P 
Sbjct: 495  GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG------STKPPSQQPGSA-KPSAQQPSPA 547

Query: 1116 TTSSSKDEEEEEEEG 1130
              S+ +  +   + G
Sbjct: 548  KPSAQQSTKPVSQTG 562



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 10/80 (12%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSL 354
           P + +PGST  PP     + PS   P S  P PS+ P     S   P  A  P  + S+ 
Sbjct: 499 PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAK-PSAQQSTK 556

Query: 355 PVS-----RPISP---SPSA 366
           PVS     +P+ P   SPSA
Sbjct: 557 PVSQTGSGKPLQPPTVSPSA 576



 Score = 31.6 bits (70), Expect = 7.9
 Identities = 52/254 (20%), Positives = 91/254 (35%), Gaps = 33/254 (12%)

Query: 1702 SSSHIAQEASPRPLLVPDEGPTALEPPT-SIPSA------SRKGSSGAPQTSRMPVPMSA 1754
            S+  ++Q  S +PL  P   P+A +PP+  +P        + +     P+ +        
Sbjct: 554  STKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTEC 613

Query: 1755 KNRPGTLDKPGKQSKLQDPRQYRQANGSAKKS-GGDFKPTSPSLPASKIPALSPSSGKSS 1813
            +    +L        L + +++   N   K++ GGD  P  PS P  K+        K++
Sbjct: 614  QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV-PSSPQPKL--------KTA 664

Query: 1814 SLPSSSGDSSNLPNPPATKPSIASNPL-------SPQTGPPAHSASLIPSVSNGSLK--- 1863
             + ++S  S + P P  T P   + P         P+  PP      +    +   K   
Sbjct: 665  PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 1864 -FQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLT 1922
               SL+        S    S+  +AP        P     +  L   +  T     P + 
Sbjct: 725  EADSLSKPAPPKEPSV--PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT---KPDIP 779

Query: 1923 SYKAQNGSSSKATP 1936
            S K Q+ +  K TP
Sbjct: 780  SSKVQSQAEEKTTP 793


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 92/498 (18%), Positives = 163/498 (32%), Gaps = 60/498 (12%)

Query: 1487 ENGDSVVQNNNTSQMSHKKVA---------PGNLRTGQQVETKSQPHSLATETRNPGGQE 1537
            +NGD  V   +TS   H KV+         P N R      + +   +  T  +    + 
Sbjct: 93   DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 152

Query: 1538 MNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGK 1597
               T  NK +  D        ++    +  S K         K LA  T    T TK   
Sbjct: 153  KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK---DLAPTSKVLAKPTPKAETTTKGPA 209

Query: 1598 KTL--QVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVR----RQEQPSIESTSP 1651
             T   +      +E   T  +       + A + P++    T +      ++P+  +T  
Sbjct: 210  LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE 269

Query: 1652 ISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEAS 1711
             + T         T +    T K    T  E +P      + ++ ++   ++       +
Sbjct: 270  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329

Query: 1712 PRPLLVPDEGPTALEPPTSIPSASRKGS---------------------SGAPQTSRMPV 1750
            P+      + P    P    P+A +K +                       +P T + P 
Sbjct: 330  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1810
            P + K+ P T  +P   +    P   ++ + +  K      PT+P  PA   P     + 
Sbjct: 390  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTT 446

Query: 1811 KSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHT 1870
                 P++  +    P P  TK    + P  P    P  +A   P         + LT T
Sbjct: 447  PKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPT 493

Query: 1871 GKGHHLSFSPQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKA 1926
                    +P+      P  L+ ++    +P +P         A    T   P+ T+ K 
Sbjct: 494  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553

Query: 1927 QNGSSSK-ATPSTAKETS 1943
               ++ K   P+T KET+
Sbjct: 554  PAPTTPKEPAPTTPKETA 571



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 79/376 (21%), Positives = 134/376 (35%), Gaps = 41/376 (10%)

Query: 1578 PKKQLAALTQAIRTGTKTGKKTL--QVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPE 1635
            PK+     T++  T TK    T         +E    T K+       E A + P+  P 
Sbjct: 385  PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK-PA 443

Query: 1636 NTVRRQEQPSIESTSPISRTDEIRKNTYR--TLDSLEQTIKQLENTISEMSPKALVDTSC 1693
             T  ++  P+       + T +    T +     + ++T       ++  +P+ L  T+ 
Sbjct: 444  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503

Query: 1694 SSNRDSVASSSHIAQEASPRPLLVPDEGPT---ALEPPTSIPSASRKGSSGAPQTSRMPV 1750
                 +            P P    +  PT   A  P T    A       AP T + P 
Sbjct: 504  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1810
            P + K    T  K    + L++P                  PT+P  PA K   L+P++ 
Sbjct: 564  PTTPKETAPTTPKGTAPTTLKEP-----------------APTTPKKPAPK--ELAPTTT 604

Query: 1811 KSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIP-SVSNGSLKFQSLTH 1869
            K    P+S+  + + P P   K +  + P  P    P   A   P   +  +LK  + T 
Sbjct: 605  KE---PTST--TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659

Query: 1870 TGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPAS---SVSLNQGAKGTRTIHTPSLTSYKA 1926
              K      +P +  G    P S +S  P+P +   +           T   P+ T+ + 
Sbjct: 660  PKKPAPKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 715

Query: 1927 QNGSSSK-ATPSTAKE 1941
               ++S+ +TP+T KE
Sbjct: 716  PPPTTSEVSTPTTTKE 731



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 57/216 (26%), Positives = 81/216 (37%), Gaps = 32/216 (14%)

Query: 924  TSTLQMSQAPQSPQI----PMNGSAMQSLFIEEIHSVSAK-NRAVSIEKAEKKWEEKRQN 978
            TST Q ++   SP+I    P+N         +     S   N+  ++E  E     K+ +
Sbjct: 104  TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163

Query: 979  LDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLE 1038
             D   GKE     +E Q+    S  +L             AP  KV L++ +P +E   +
Sbjct: 164  TD---GKEKTTSAKETQSIEKTSAKDL-------------APTSKV-LAKPTPKAETTTK 206

Query: 1039 KLG---GKSPPPPPPPPRRSYLPGSGLTTT-RSGDVVYTGRKENITAKASSEDAGPSPQT 1094
                   K P P  P    S  P     TT +S            T  A +    P+P T
Sbjct: 207  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 266

Query: 1095 RATKYPA----EEPASAWTPSPPPVTTSSSKDEEEE 1126
              TK PA    +EPA   T  P P TT S+    +E
Sbjct: 267  --TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 53/228 (23%), Positives = 74/228 (32%), Gaps = 18/228 (7%)

Query: 906  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 965
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 530  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 582

Query: 966  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 1024
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 583  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637

Query: 1025 ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1082
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 638  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697

Query: 1083 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEE 1127
               A +    P+P T  T  P     S  T +  P T   S DE   E
Sbjct: 698  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 42/228 (18%), Positives = 80/228 (35%), Gaps = 31/228 (13%)

Query: 1624 EIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKN-TYRTLDSLEQTIKQ--LENTI 1680
            E A + P+ T   T++     + +  +P        K  T  T D    T  +     T 
Sbjct: 569  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628

Query: 1681 SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPS------- 1733
             E +P    + + ++ + +  ++       +P+     +  PT  + PTS  S       
Sbjct: 629  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688

Query: 1734 ----ASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGD 1789
                A       AP T + P P + +  P T  +    +  ++P    ++          
Sbjct: 689  PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE------- 741

Query: 1790 FKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIAS 1837
               ++P L A   P    +S K   +P++         P ATKP + +
Sbjct: 742  ---STPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTT 779


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 92/498 (18%), Positives = 163/498 (32%), Gaps = 60/498 (12%)

Query: 1487 ENGDSVVQNNNTSQMSHKKVA---------PGNLRTGQQVETKSQPHSLATETRNPGGQE 1537
            +NGD  V   +TS   H KV+         P N R      + +   +  T  +    + 
Sbjct: 134  DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 193

Query: 1538 MNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGK 1597
               T  NK +  D        ++    +  S K         K LA  T    T TK   
Sbjct: 194  KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK---DLAPTSKVLAKPTPKAETTTKGPA 250

Query: 1598 KTL--QVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVR----RQEQPSIESTSP 1651
             T   +      +E   T  +       + A + P++    T +      ++P+  +T  
Sbjct: 251  LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE 310

Query: 1652 ISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEAS 1711
             + T         T +    T K    T  E +P      + ++ ++   ++       +
Sbjct: 311  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370

Query: 1712 PRPLLVPDEGPTALEPPTSIPSASRKGS---------------------SGAPQTSRMPV 1750
            P+      + P    P    P+A +K +                       +P T + P 
Sbjct: 371  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1810
            P + K+ P T  +P   +    P   ++ + +  K      PT+P  PA   P     + 
Sbjct: 431  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTT 487

Query: 1811 KSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHT 1870
                 P++  +    P P  TK    + P  P    P  +A   P         + LT T
Sbjct: 488  PKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPT 534

Query: 1871 GKGHHLSFSPQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKA 1926
                    +P+      P  L+ ++    +P +P         A    T   P+ T+ K 
Sbjct: 535  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594

Query: 1927 QNGSSSK-ATPSTAKETS 1943
               ++ K   P+T KET+
Sbjct: 595  PAPTTPKEPAPTTPKETA 612



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 79/376 (21%), Positives = 134/376 (35%), Gaps = 41/376 (10%)

Query: 1578 PKKQLAALTQAIRTGTKTGKKTL--QVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPE 1635
            PK+     T++  T TK    T         +E    T K+       E A + P+  P 
Sbjct: 426  PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK-PA 484

Query: 1636 NTVRRQEQPSIESTSPISRTDEIRKNTYR--TLDSLEQTIKQLENTISEMSPKALVDTSC 1693
             T  ++  P+       + T +    T +     + ++T       ++  +P+ L  T+ 
Sbjct: 485  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 544

Query: 1694 SSNRDSVASSSHIAQEASPRPLLVPDEGPT---ALEPPTSIPSASRKGSSGAPQTSRMPV 1750
                 +            P P    +  PT   A  P T    A       AP T + P 
Sbjct: 545  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1810
            P + K    T  K    + L++P                  PT+P  PA K   L+P++ 
Sbjct: 605  PTTPKETAPTTPKGTAPTTLKEP-----------------APTTPKKPAPK--ELAPTTT 645

Query: 1811 KSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIP-SVSNGSLKFQSLTH 1869
            K    P+S+  + + P P   K +  + P  P    P   A   P   +  +LK  + T 
Sbjct: 646  KE---PTST--TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700

Query: 1870 TGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPAS---SVSLNQGAKGTRTIHTPSLTSYKA 1926
              K      +P +  G    P S +S  P+P +   +           T   P+ T+ + 
Sbjct: 701  PKKPAPKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 756

Query: 1927 QNGSSSK-ATPSTAKE 1941
               ++S+ +TP+T KE
Sbjct: 757  PPPTTSEVSTPTTTKE 772



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 57/216 (26%), Positives = 81/216 (37%), Gaps = 32/216 (14%)

Query: 924  TSTLQMSQAPQSPQI----PMNGSAMQSLFIEEIHSVSAK-NRAVSIEKAEKKWEEKRQN 978
            TST Q ++   SP+I    P+N         +     S   N+  ++E  E     K+ +
Sbjct: 145  TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204

Query: 979  LDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLE 1038
             D   GKE     +E Q+    S  +L             AP  KV L++ +P +E   +
Sbjct: 205  TD---GKEKTTSAKETQSIEKTSAKDL-------------APTSKV-LAKPTPKAETTTK 247

Query: 1039 KLG---GKSPPPPPPPPRRSYLPGSGLTTT-RSGDVVYTGRKENITAKASSEDAGPSPQT 1094
                   K P P  P    S  P     TT +S            T  A +    P+P T
Sbjct: 248  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 307

Query: 1095 RATKYPA----EEPASAWTPSPPPVTTSSSKDEEEE 1126
              TK PA    +EPA   T  P P TT S+    +E
Sbjct: 308  --TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 53/228 (23%), Positives = 74/228 (32%), Gaps = 18/228 (7%)

Query: 906  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 965
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 571  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 623

Query: 966  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 1024
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 624  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678

Query: 1025 ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1082
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 679  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738

Query: 1083 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEE 1127
               A +    P+P T  T  P     S  T +  P T   S DE   E
Sbjct: 739  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 42/228 (18%), Positives = 80/228 (35%), Gaps = 31/228 (13%)

Query: 1624 EIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKN-TYRTLDSLEQTIKQ--LENTI 1680
            E A + P+ T   T++     + +  +P        K  T  T D    T  +     T 
Sbjct: 610  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669

Query: 1681 SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPS------- 1733
             E +P    + + ++ + +  ++       +P+     +  PT  + PTS  S       
Sbjct: 670  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729

Query: 1734 ----ASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGD 1789
                A       AP T + P P + +  P T  +    +  ++P    ++          
Sbjct: 730  PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE------- 782

Query: 1790 FKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIAS 1837
               ++P L A   P    +S K   +P++         P ATKP + +
Sbjct: 783  ---STPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTT 820


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 92/498 (18%), Positives = 163/498 (32%), Gaps = 60/498 (12%)

Query: 1487 ENGDSVVQNNNTSQMSHKKVA---------PGNLRTGQQVETKSQPHSLATETRNPGGQE 1537
            +NGD  V   +TS   H KV+         P N R      + +   +  T  +    + 
Sbjct: 186  DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 245

Query: 1538 MNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGK 1597
               T  NK +  D        ++    +  S K         K LA  T    T TK   
Sbjct: 246  KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP---TSKVLAKPTPKAETTTKGPA 302

Query: 1598 KTL--QVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQ----EQPSIESTSP 1651
             T   +      +E   T  +       + A + P++    T +      ++P+  +T  
Sbjct: 303  LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE 362

Query: 1652 ISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEAS 1711
             + T         T +    T K    T  E +P      + ++ ++   ++       +
Sbjct: 363  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422

Query: 1712 PRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQ---------------------TSRMPV 1750
            P+      + P    P    P+A +K +   P+                     T + P 
Sbjct: 423  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1810
            P + K+ P T  +P   +    P   ++ + +  K      PT+P  PA   P     + 
Sbjct: 483  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTT 539

Query: 1811 KSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHT 1870
                 P++  +    P P  TK    + P  P    P  +A   P         + LT T
Sbjct: 540  PKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPT 586

Query: 1871 GKGHHLSFSPQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKA 1926
                    +P+      P  L+ ++    +P +P         A    T   P+ T+ K 
Sbjct: 587  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646

Query: 1927 QNGSSSK-ATPSTAKETS 1943
               ++ K   P+T KET+
Sbjct: 647  PAPTTPKEPAPTTPKETA 664



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 157/823 (19%), Positives = 271/823 (32%), Gaps = 102/823 (12%)

Query: 1149 NSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTG 1208
            +S     PS A   +K T   +  PP +KK  +                  +E +++T  
Sbjct: 74   SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKV-----------------IESEEIT-- 114

Query: 1209 AVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSL-----LRDSRNYSQETV 1263
                 +    E    +S S +S +S    +I   +NS +N  L     ++D++    +  
Sbjct: 115  ----EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 170

Query: 1264 PKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHT 1323
            P          P+ DE   G      + + PDT   T  + K     K  T K  ++   
Sbjct: 171  PTPK------PPVVDEAGSGLDNGDFKVTTPDTS--TTQHNKVSTSPKITTAK-PINPRP 221

Query: 1324 RLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAATDNI 1383
             L  +S        +E   T   +  +  KE    N   + DG+  ++S  E  +     
Sbjct: 222  SLPPNS-----DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 276

Query: 1384 AFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQ-----EGTDNEDPVVCL 1438
            A  +  T+ +VL+        + KG  + T      KE TP         T  E     +
Sbjct: 277  AKDLAPTS-KVLAKPTPKAETTTKGPALTTP-----KEPTPTTPKEPASTTPKEPTPTTI 330

Query: 1439 DKKPVIIIFDEPMDIRSA----YKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQ 1494
               P       P   +SA     +   T  +E      +       +E        +   
Sbjct: 331  KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 390

Query: 1495 NNNTSQMSHKKVAPGNLR----TGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVD 1550
                +  + KK AP   +    T  +  T + P   A  T+ P                 
Sbjct: 391  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450

Query: 1551 SPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTL--QVVVYEEE 1608
                +        +   +  K+     PK+     T++  T TK    T         +E
Sbjct: 451  PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510

Query: 1609 EEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYR--TL 1666
                T K+       E A + P+  P  T  ++  P+       + T +    T +    
Sbjct: 511  PSPTTTKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569

Query: 1667 DSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPT--- 1723
             + ++T       ++  +P+ L  T+      +            P P    +  PT   
Sbjct: 570  TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629

Query: 1724 ALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSA 1783
            A  P T    A       AP T + P P + K    T  K    + L++P          
Sbjct: 630  AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---------- 679

Query: 1784 KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ 1843
                    PT+P  PA K   L+P++ K    P+S+  + + P P   K +  + P  P 
Sbjct: 680  -------APTTPKKPAPK--ELAPTTTKE---PTST--TCDKPAPTTPKGTAPTTPKEPA 725

Query: 1844 TGPPAHSASLIP-SVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPAS 1902
               P   A   P   +  +LK  + T   K      +P +  G    P S +S  P+P +
Sbjct: 726  PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG----PTSTTSDKPAPTT 781

Query: 1903 ---SVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-ATPSTAKE 1941
               +           T   P+ T+ +    ++S+ +TP+T KE
Sbjct: 782  PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 824



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 92/489 (18%), Positives = 169/489 (34%), Gaps = 36/489 (7%)

Query: 1470 ELERMMMEEKIEEEEEEENGDSVVQNNNT-SQMSHKKVAPGNLRTGQQVETKSQPHSLAT 1528
            E E +  E  + E +E  +  S   +++T  ++   K +  N    ++++ K    +   
Sbjct: 109  ESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK 168

Query: 1529 ETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFE--SPKKKFKFKFPKKQLAALT 1586
            +   P    ++       S +D+ + +    D +  Q    S   K     P     +L 
Sbjct: 169  KKPTPKPPVVDEAG----SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 224

Query: 1587 QAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSI 1646
                T  +T     +    E +E   T KQ               D  E T   +E  SI
Sbjct: 225  PNSDTSKETSLTVNKETTVETKETTTTNKQTST------------DGKEKTTSAKETQSI 272

Query: 1647 ESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRD----SVAS 1702
            E TS        +     T  +   T      T  E +P    + + ++ ++    ++ S
Sbjct: 273  EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 332

Query: 1703 SSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLD 1762
            +    +E +P         P    P T+   A       AP T++ P P + K+ P T  
Sbjct: 333  APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 392

Query: 1763 KPGKQS-KLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGD 1821
            +P   + K   P   ++   +  K   +  PT+P  PA      +P++ K  +  +    
Sbjct: 393  EPAPTTPKKPAPTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449

Query: 1822 SSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSN-----GSLKFQSLTHTGKGHHL 1876
            +   P  PA  P+    P    T  P+ +    P+ +       + K  + T T      
Sbjct: 450  APTTPKEPA--PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 507

Query: 1877 SFSPQSQNGRAPPPLS-FSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-A 1934
               P     + P P +    +P +P              T   P+ T+ K    ++ K  
Sbjct: 508  PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567

Query: 1935 TPSTAKETS 1943
             P+T KET+
Sbjct: 568  APTTPKETA 576



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 57/216 (26%), Positives = 81/216 (37%), Gaps = 32/216 (14%)

Query: 924  TSTLQMSQAPQSPQI----PMNGSAMQSLFIEEIHSVSAK-NRAVSIEKAEKKWEEKRQN 978
            TST Q ++   SP+I    P+N         +     S   N+  ++E  E     K+ +
Sbjct: 197  TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 256

Query: 979  LDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLE 1038
             D   GKE     +E Q+    S  +L             AP  KV L++ +P +E   +
Sbjct: 257  TD---GKEKTTSAKETQSIEKTSAKDL-------------APTSKV-LAKPTPKAETTTK 299

Query: 1039 KLG---GKSPPPPPPPPRRSYLPGSGLTTT-RSGDVVYTGRKENITAKASSEDAGPSPQT 1094
                   K P P  P    S  P     TT +S            T  A +    P+P T
Sbjct: 300  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359

Query: 1095 RATKYPA----EEPASAWTPSPPPVTTSSSKDEEEE 1126
              TK PA    +EPA   T  P P TT S+    +E
Sbjct: 360  --TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 53/228 (23%), Positives = 74/228 (32%), Gaps = 18/228 (7%)

Query: 906  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 965
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 623  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 675

Query: 966  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 1024
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 676  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730

Query: 1025 ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1082
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 731  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790

Query: 1083 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEE 1127
               A +    P+P T  T  P     S  T +  P T   S DE   E
Sbjct: 791  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 42/228 (18%), Positives = 80/228 (35%), Gaps = 31/228 (13%)

Query: 1624 EIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKN-TYRTLDSLEQTIKQ--LENTI 1680
            E A + P+ T   T++     + +  +P        K  T  T D    T  +     T 
Sbjct: 662  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721

Query: 1681 SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPS------- 1733
             E +P    + + ++ + +  ++       +P+     +  PT  + PTS  S       
Sbjct: 722  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781

Query: 1734 ----ASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGD 1789
                A       AP T + P P + +  P T  +    +  ++P    ++          
Sbjct: 782  PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE------- 834

Query: 1790 FKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIAS 1837
               ++P L A   P    +S K   +P++         P ATKP + +
Sbjct: 835  ---STPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTT 872


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 92/498 (18%), Positives = 163/498 (32%), Gaps = 60/498 (12%)

Query: 1487 ENGDSVVQNNNTSQMSHKKVA---------PGNLRTGQQVETKSQPHSLATETRNPGGQE 1537
            +NGD  V   +TS   H KV+         P N R      + +   +  T  +    + 
Sbjct: 227  DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 286

Query: 1538 MNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGK 1597
               T  NK +  D        ++    +  S K         K LA  T    T TK   
Sbjct: 287  KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP---TSKVLAKPTPKAETTTKGPA 343

Query: 1598 KTL--QVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQ----EQPSIESTSP 1651
             T   +      +E   T  +       + A + P++    T +      ++P+  +T  
Sbjct: 344  LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE 403

Query: 1652 ISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEAS 1711
             + T         T +    T K    T  E +P      + ++ ++   ++       +
Sbjct: 404  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463

Query: 1712 PRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQ---------------------TSRMPV 1750
            P+      + P    P    P+A +K +   P+                     T + P 
Sbjct: 464  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG 1810
            P + K+ P T  +P   +    P   ++ + +  K      PT+P  PA   P     + 
Sbjct: 524  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTT 580

Query: 1811 KSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHT 1870
                 P++  +    P P  TK    + P  P    P  +A   P         + LT T
Sbjct: 581  PKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPT 627

Query: 1871 GKGHHLSFSPQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKA 1926
                    +P+      P  L+ ++    +P +P         A    T   P+ T+ K 
Sbjct: 628  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687

Query: 1927 QNGSSSK-ATPSTAKETS 1943
               ++ K   P+T KET+
Sbjct: 688  PAPTTPKEPAPTTPKETA 705



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 157/823 (19%), Positives = 271/823 (32%), Gaps = 102/823 (12%)

Query: 1149 NSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTG 1208
            +S     PS A   +K T   +  PP +KK  +                  +E +++T  
Sbjct: 115  SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKV-----------------IESEEIT-- 155

Query: 1209 AVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSL-----LRDSRNYSQETV 1263
                 +    E    +S S +S +S    +I   +NS +N  L     ++D++    +  
Sbjct: 156  ----EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 211

Query: 1264 PKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSSHT 1323
            P          P+ DE   G      + + PDT   T  + K     K  T K  ++   
Sbjct: 212  PTPK------PPVVDEAGSGLDNGDFKVTTPDTS--TTQHNKVSTSPKITTAK-PINPRP 262

Query: 1324 RLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAATDNI 1383
             L  +S        +E   T   +  +  KE    N   + DG+  ++S  E  +     
Sbjct: 263  SLPPNS-----DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 317

Query: 1384 AFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQ-----EGTDNEDPVVCL 1438
            A  +  T+ +VL+        + KG  + T      KE TP         T  E     +
Sbjct: 318  AKDLAPTS-KVLAKPTPKAETTTKGPALTTP-----KEPTPTTPKEPASTTPKEPTPTTI 371

Query: 1439 DKKPVIIIFDEPMDIRSA----YKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQ 1494
               P       P   +SA     +   T  +E      +       +E        +   
Sbjct: 372  KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 431

Query: 1495 NNNTSQMSHKKVAPGNLR----TGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVD 1550
                +  + KK AP   +    T  +  T + P   A  T+ P                 
Sbjct: 432  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491

Query: 1551 SPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTL--QVVVYEEE 1608
                +        +   +  K+     PK+     T++  T TK    T         +E
Sbjct: 492  PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551

Query: 1609 EEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYR--TL 1666
                T K+       E A + P+  P  T  ++  P+       + T +    T +    
Sbjct: 552  PSPTTTKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610

Query: 1667 DSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPT--- 1723
             + ++T       ++  +P+ L  T+      +            P P    +  PT   
Sbjct: 611  TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 670

Query: 1724 ALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSA 1783
            A  P T    A       AP T + P P + K    T  K    + L++P          
Sbjct: 671  AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---------- 720

Query: 1784 KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ 1843
                    PT+P  PA K   L+P++ K    P+S+  + + P P   K +  + P  P 
Sbjct: 721  -------APTTPKKPAPK--ELAPTTTKE---PTST--TCDKPAPTTPKGTAPTTPKEPA 766

Query: 1844 TGPPAHSASLIP-SVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPAS 1902
               P   A   P   +  +LK  + T   K      +P +  G    P S +S  P+P +
Sbjct: 767  PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG----PTSTTSDKPAPTT 822

Query: 1903 ---SVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-ATPSTAKE 1941
               +           T   P+ T+ +    ++S+ +TP+T KE
Sbjct: 823  PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 865



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 92/489 (18%), Positives = 169/489 (34%), Gaps = 36/489 (7%)

Query: 1470 ELERMMMEEKIEEEEEEENGDSVVQNNNT-SQMSHKKVAPGNLRTGQQVETKSQPHSLAT 1528
            E E +  E  + E +E  +  S   +++T  ++   K +  N    ++++ K    +   
Sbjct: 150  ESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK 209

Query: 1529 ETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFE--SPKKKFKFKFPKKQLAALT 1586
            +   P    ++       S +D+ + +    D +  Q    S   K     P     +L 
Sbjct: 210  KKPTPKPPVVDEAG----SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 265

Query: 1587 QAIRTGTKTGKKTLQVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSI 1646
                T  +T     +    E +E   T KQ               D  E T   +E  SI
Sbjct: 266  PNSDTSKETSLTVNKETTVETKETTTTNKQTST------------DGKEKTTSAKETQSI 313

Query: 1647 ESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRD----SVAS 1702
            E TS        +     T  +   T      T  E +P    + + ++ ++    ++ S
Sbjct: 314  EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 373

Query: 1703 SSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLD 1762
            +    +E +P         P    P T+   A       AP T++ P P + K+ P T  
Sbjct: 374  APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 433

Query: 1763 KPGKQS-KLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGD 1821
            +P   + K   P   ++   +  K   +  PT+P  PA      +P++ K  +  +    
Sbjct: 434  EPAPTTPKKPAPTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 490

Query: 1822 SSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSN-----GSLKFQSLTHTGKGHHL 1876
            +   P  PA  P+    P    T  P+ +    P+ +       + K  + T T      
Sbjct: 491  APTTPKEPA--PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 548

Query: 1877 SFSPQSQNGRAPPPLS-FSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-A 1934
               P     + P P +    +P +P              T   P+ T+ K    ++ K  
Sbjct: 549  PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608

Query: 1935 TPSTAKETS 1943
             P+T KET+
Sbjct: 609  APTTPKETA 617



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 57/216 (26%), Positives = 81/216 (37%), Gaps = 32/216 (14%)

Query: 924  TSTLQMSQAPQSPQI----PMNGSAMQSLFIEEIHSVSAK-NRAVSIEKAEKKWEEKRQN 978
            TST Q ++   SP+I    P+N         +     S   N+  ++E  E     K+ +
Sbjct: 238  TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 297

Query: 979  LDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLE 1038
             D   GKE     +E Q+    S  +L             AP  KV L++ +P +E   +
Sbjct: 298  TD---GKEKTTSAKETQSIEKTSAKDL-------------APTSKV-LAKPTPKAETTTK 340

Query: 1039 KLG---GKSPPPPPPPPRRSYLPGSGLTTT-RSGDVVYTGRKENITAKASSEDAGPSPQT 1094
                   K P P  P    S  P     TT +S            T  A +    P+P T
Sbjct: 341  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400

Query: 1095 RATKYPA----EEPASAWTPSPPPVTTSSSKDEEEE 1126
              TK PA    +EPA   T  P P TT S+    +E
Sbjct: 401  --TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 53/228 (23%), Positives = 74/228 (32%), Gaps = 18/228 (7%)

Query: 906  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 965
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 664  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 716

Query: 966  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 1024
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 717  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771

Query: 1025 ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1082
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 772  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831

Query: 1083 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEE 1127
               A +    P+P T  T  P     S  T +  P T   S DE   E
Sbjct: 832  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 42/228 (18%), Positives = 80/228 (35%), Gaps = 31/228 (13%)

Query: 1624 EIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKN-TYRTLDSLEQTIKQ--LENTI 1680
            E A + P+ T   T++     + +  +P        K  T  T D    T  +     T 
Sbjct: 703  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762

Query: 1681 SEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPS------- 1733
             E +P    + + ++ + +  ++       +P+     +  PT  + PTS  S       
Sbjct: 763  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822

Query: 1734 ----ASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGD 1789
                A       AP T + P P + +  P T  +    +  ++P    ++          
Sbjct: 823  PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE------- 875

Query: 1790 FKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIAS 1837
               ++P L A   P    +S K   +P++         P ATKP + +
Sbjct: 876  ---STPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTT 913


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 73/275 (26%), Positives = 104/275 (37%), Gaps = 39/275 (14%)

Query: 1699 SVASSSHIAQEASPRPLLVP-DEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNR 1757
            S+ SSS     A+P P  +P    P     P +    S KG    P     P P +A   
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA-TP 970

Query: 1758 PGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPS 1817
            P     P   S    P        S K  GG   P+    P    PA++P S K S   +
Sbjct: 971  PSPKGGPATPSPKGAPTPPAATPPSPK--GGPATPSPKGAPTP--PAVTPPSPKGSPAAT 1026

Query: 1818 SSGDSSNLP---NPPATKPSIASNPL-------------SPQTGPPAHS---ASLIPSVS 1858
                 ++ P    PP+ K S A+ PL             SP+ GP   S   A   P+ +
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086

Query: 1859 NGSLKFQSLTHTGKGHHL---SFSPQSQNGRAPP-----PLSFSSSPPSPASSVSLNQGA 1910
              S K    T + KG  +   +  P  + G A P     P + +++PPSP   ++     
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA-TPPP 1145

Query: 1911 KGTRTIHTPSLTSYKAQNGSSS---KATPSTAKET 1942
            KG  T  TP+ T    + G ++   K  P+T   T
Sbjct: 1146 KGAPT--TPAATPPSPKGGLATPPPKGAPTTPAAT 1178



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 73/296 (24%), Positives = 108/296 (36%), Gaps = 53/296 (17%)

Query: 1690 DTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSA--------------- 1734
            D+  S+   S  + +++A   SP  + V    P    PPT   SA               
Sbjct: 774  DSGASATASSKGTLTYLADSPSPLGVSV---SPQTKRPPTKKGSAGPDTPIGNLSSPVSP 830

Query: 1735 -----------SRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSA 1783
                       S +GS  +P T+  P P S K  P     P   + L           + 
Sbjct: 831  VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP----TPSAVTPLSPKGVTLPPKETP 886

Query: 1784 KKSGGD--FKPTSPSLPASK-IPALSPSSG---KSSSLPSSSGDSSNLPNPPATKPSIAS 1837
              S  +  F    P+ PA K  PALS +S    K+ + P+  G  ++ P+P       A+
Sbjct: 887  TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS-PSPKGAPTPPAA 945

Query: 1838 NPLSPQTGPPAHS---ASLIPSVSNGSLKFQSLTHTGKG---HHLSFSPQSQNGRAPP-- 1889
             P SP+ GP   S   A   P+ +  S K    T + KG      +  P  + G A P  
Sbjct: 946  TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005

Query: 1890 ---PLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKET 1942
               P   + +PPSP  S +     KG  T   P+ T    +   ++   P  A  T
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGAST--PPAATPPSPKGSPAATPLPKGAPTT 1059



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 73/282 (25%), Positives = 111/282 (39%), Gaps = 44/282 (15%)

Query: 1673 IKQLENTISEMSPKALVDTSCS--SNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTS 1730
            I  L + +S +    L + S S   ++DS A++       SP P       P     P++
Sbjct: 821  IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH------SPTP-----PSPKGAPTPSA 869

Query: 1731 IPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDF 1790
            +   S KG +  P+ +  P   S  N P   + P   +  Q P      + S KK+    
Sbjct: 870  VTPLSPKGVTLPPKETPTP---SVVNLPFPKEGPATPAPKQAPA-LSMTSSSPKKARAT- 924

Query: 1791 KPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHS 1850
             P    +PAS  P  +P+   ++      G ++  P    T P  A+ P SP+ GP   S
Sbjct: 925  -PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP--AATPPSPKGGPATPS 981

Query: 1851 ---ASLIPSVSNGSLKFQSLTHTGKGHHL--SFSPQSQNGR----------APPPLSFSS 1895
               A   P+ +  S K    T + KG     + +P S  G           + PP +   
Sbjct: 982  PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA--- 1038

Query: 1896 SPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPS 1937
            +PPSP  S +     KG  T  TP+ T    + G    ATPS
Sbjct: 1039 TPPSPKGSPAATPLPKGAPT--TPAATLPSPKGG---PATPS 1075



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 69/265 (26%), Positives = 103/265 (38%), Gaps = 36/265 (13%)

Query: 1701 ASSSHIAQEASPR--PLLVPDEG---PTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAK 1755
            A ++  A   SP+  P   P +G   P A  PP+     +     GAP  + +  P S K
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA-VVTPPSPK 1298

Query: 1756 NRPGTLDKPGKQSK-LQDPRQYRQANGSAKKSGGDFKPTSPSL--PASK----IPALSPS 1808
              P T    G  +     P   + + G+    G    PT P++  P+ K    +PA +PS
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA---PTPPAVTPPSPKGTPTLPATTPS 1355

Query: 1809 SGKSSSLPSSSGDSSNLPNPPATKPSI----ASNPLSPQTGPPAHSASLIPS----VSNG 1860
            S    + PSS       P PPA  PS     A  P SP+ GP   S    P+    +   
Sbjct: 1356 SKGGPTTPSSKEG----PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411

Query: 1861 SLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV----SLNQGAKGTRTI 1916
              K  +   T +G     +  S+    PP ++  S   +PA+S          +KG  T+
Sbjct: 1412 PKKAPATPVTREG----AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467

Query: 1917 HTPSLTSYKAQNGSSSKATPSTAKE 1941
               +  S K        AT S+ K+
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKK 1492



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 70/280 (25%), Positives = 100/280 (35%), Gaps = 48/280 (17%)

Query: 1695 SNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSA------SRKGSSGAPQTSRM 1748
            S +  +A+  H     +P       +G  A  PP   P+       S KG    P     
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171

Query: 1749 PVPMSAK--NRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALS 1806
            P   +A   +  G L  P  +     P     A       GG   P+    P +  PA +
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTP-----AATPPSPKGGLATPSPKGAPTT--PAAT 1224

Query: 1807 PSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTG---PPAHSASLIPSVSNGSLK 1863
            P        PS  G  +  P+P     + A+ P SP+ G   PP   A   P+ +  SLK
Sbjct: 1225 P--------PSPKGGLAT-PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275

Query: 1864 FQSLT--HTGKGHHLSFSPQSQNG---RAPP---PLSFSSSPPSPASSVSL--NQGA--- 1910
                T  H G  +    +P S  G    +PP   P   +++PPSP  S      +GA   
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335

Query: 1911 --------KGTRTIHTPSLTSYKAQNGSSSKATPSTAKET 1942
                    KGT T+   + +S       SSK  P+    T
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 70/292 (23%), Positives = 102/292 (34%), Gaps = 72/292 (24%)

Query: 1682 EMSPKALVDTSCSSNRDSVASSSHIAQEASPR----PLLVPDEGPTALEPPTSIPSASRK 1737
            +++P A+   S    + + A+S+     A+P     P L     P+  EPP     A+  
Sbjct: 1432 DLTPPAVTPVSL---KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488

Query: 1738 GSSGAPQTSRMPVPMSAKNRPGTL-----DKPGKQSKLQDPRQYRQANGSAKKSGGDFKP 1792
                AP T   P PM A   P  +     + P   S  +DP     A   +KK+     P
Sbjct: 1489 SPKKAPAT---PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIA-PTATLLSKKTPATLAP 1544

Query: 1793 T---------------SPSLPASKIPALSPSSGKSSSLPSSSGDS-------SNLPNPPA 1830
                            +P++P  K    +PSS ++SS P+ +  +         L  PPA
Sbjct: 1545 KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPA 1604

Query: 1831 -TKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPP 1889
             T PS    P  P   PP+           G+     +T                     
Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT--------------------- 1643

Query: 1890 PLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKE 1941
            P S   SP SPA SV+   GA           T  +A  G  +K  P+  KE
Sbjct: 1644 PSSLKDSPTSPA-SVTCKMGA-----------TVPQASKGLPAKKGPTALKE 1683



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 5/75 (6%)

Query: 295  PGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYG--GTRSMVVPGNATIPRD 349
            P +P P     PP A P SP   P+TP P   P  P+  P    G  +   P  A  P  
Sbjct: 931  PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990

Query: 350  RISSLPVSRPISPSP 364
                 P   P +PSP
Sbjct: 991  ATPPSPKGGPATPSP 1005



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 9/78 (11%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P P     PP A P SP   P+TP P   P  P+  P     S   P     P+  
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS---PAATPFPKG- 1031

Query: 351  ISSLPVSRPISP--SPSA 366
             S+ P + P SP  SP+A
Sbjct: 1032 ASTPPAATPPSPKGSPAA 1049



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 8/81 (9%)

Query: 291  RGDGPGAPRPGSTAHPPHAIP----NSPPSTPVPHSMPPSPSRI---PYGGTRSMVVPGN 343
            +G     P P   + PP A P     SP +TP+P   P +P+     P GG  +  + G 
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 344  ATIPRDRISSLPVSRPISPSP 364
             T P     S P   P +PSP
Sbjct: 1080 PTPPAATPPS-PKGGPATPSP 1099



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 64/261 (24%), Positives = 93/261 (35%), Gaps = 61/261 (23%)

Query: 1707 AQEASPRPLLVPDEGP-----TALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTL 1761
            A E++P       +GP     +A  PP   P  S K  S  P ++  P P+    +  + 
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPIC-PDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 1762 DKPGK-------------QSKLQDP------RQYRQANGSAKKSGGDFKPTSPSLPASKI 1802
               GK             +SK   P       +      SA  S     P S  L  S +
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807

Query: 1803 PALSPSSGKSSSLPSSSG---DSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSN 1859
            P L P   K   LPSS G   +S + P  PA +  +   PL P            P   +
Sbjct: 1808 PTLPP---KQQFLPSSPGLVLESPSKPLAPADEDELL--PLIP------------PEPIS 1850

Query: 1860 GSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTP 1919
            G + FQS+        L   P  ++   P P       PS    V+ N    GT +    
Sbjct: 1851 GGVPFQSV--------LVNMPTPKSAGIPVP------TPSAKQPVTKNNKGSGTESDSDE 1896

Query: 1920 SLTSYKAQNGSSSKATPSTAK 1940
            S+   + Q+  S++AT   A+
Sbjct: 1897 SVPELEEQD--STQATTQQAQ 1915



 Score = 34.7 bits (78), Expect = 0.93
 Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 10/78 (12%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P P     PP A P SP   P+TP P   P  P+  P         P     P   
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP--- 1009

Query: 351  ISSLPVSRPISP--SPSA 366
              + P   P SP  SP+A
Sbjct: 1010 --TPPAVTPPSPKGSPAA 1025



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 57/255 (22%), Positives = 89/255 (34%), Gaps = 51/255 (20%)

Query: 1692 SCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVP 1751
            +C S   S    S+I +  SP  L++    P   EP T + +  R      P +  +P P
Sbjct: 461  TCVSPPMSSGPISNI-EPTSPAALVMAPVAPK--EPSTQVATTLR-----IPVSPPLPDP 512

Query: 1752 MSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGK 1811
               KN P ++        ++ P Q       A   G  F P    L   K P + P    
Sbjct: 513  EDLKNLPSSV-------LVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPL--- 562

Query: 1812 SSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHT- 1870
                         +   P   PS  S   SP+          IP     +L  +SL    
Sbjct: 563  -------------VQAAPKNSPSFQSTSSSPE----------IPLSPEATLAKKSLGEPL 599

Query: 1871 --GKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQN 1928
              GK      SP   N  A    + S + P  A  +  +       ++ TP++ ++  ++
Sbjct: 600  PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKS-------SLITPTVAAFPLES 652

Query: 1929 GSSSKATPSTAKETS 1943
               +   P+TAK TS
Sbjct: 653  ADPAGVAPTTAKGTS 667



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 8/72 (11%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P       PP A P SP   P+TP P   P  P+  P          G AT P   
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-----PSPKGGLATPPHKG 1124

Query: 351  ISSLPVSRPISP 362
              + P + P SP
Sbjct: 1125 APTTPAATPPSP 1136



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP    P     PP A P SP   P TP P   P  P+  P     +  +P  AT P  +
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP--ATTPSSK 1357

Query: 351  ISSLPVSRPISPSPSA 366
                  S    P+P A
Sbjct: 1358 GGPTTPSSKEGPTPPA 1373



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 36/129 (27%), Positives = 44/129 (34%), Gaps = 20/129 (15%)

Query: 1008 PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---PPPPPRRSYLPGSGLTT 1064
            P AT P P+G       + +  +P +     K G  +PPP   P PP         GL T
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280

Query: 1065 TRSGDVVYTGRKENITAKASSEDAGP--SPQTRATKYPAEEPAS----------AWTPSP 1112
                   + G          S   GP  SP   A   PA  P S             P+P
Sbjct: 1281 P-----PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335

Query: 1113 PPVTTSSSK 1121
            P VT  S K
Sbjct: 1336 PAVTPPSPK 1344



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 15/81 (18%)

Query: 294  GPGAPRPGSTAHPPHAIPNSPPSTPV-----------PHSMPPSPSRIPYGGTRSMVVPG 342
            GP  P P     PP   P SP  +P            P + PPSP   P     + +  G
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP---AATPLPKG 1055

Query: 343  NATIPRDRISSLPVSRPISPS 363
              T P   + S P   P +PS
Sbjct: 1056 APTTPAATLPS-PKGGPATPS 1075



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 25/69 (36%), Positives = 30/69 (43%), Gaps = 6/69 (8%)

Query: 296  GAPRPGSTAHPPHAIPNSPPSTPVPHSM-PPSPSRIPYGGTRSMVVPGNATIPRDRISSL 354
            GAP P     PP     SP   P P ++ PPSP +    G  +    G  T P    SSL
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK----GPATPAPKGTPTSPPVTPSSL 1647

Query: 355  PVSRPISPS 363
              S P SP+
Sbjct: 1648 KDS-PTSPA 1655



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 8/72 (11%)

Query: 294  GPGAPRPGSTAHPPHAIPNSPP---STPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P P     PP A P SP    +TP     P +P+  P          G AT P   
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP-----PSPKGGLATPPPKG 1147

Query: 351  ISSLPVSRPISP 362
              + P + P SP
Sbjct: 1148 APTTPAATPPSP 1159



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 13/80 (16%)

Query: 295  PGAPRPGSTAHPPHAIPNSPPSTP---------VPHSMPPSPSRIPYGGTRSMVVPGNAT 345
            P +P+ G    PP   P  P +TP          PH   P+P+ +    T      G AT
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV----TPPSPKGGPAT 1303

Query: 346  IPRDRISSLPVSRPISPSPS 365
             P     + P + P SP  S
Sbjct: 1304 SPPKGAPTPPAATPPSPKGS 1323



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 22/77 (28%), Positives = 28/77 (36%), Gaps = 4/77 (5%)

Query: 297  APRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRD-RIS 352
            +P P     PP   P SP   P+TP P   P SP   P     S   P + T      + 
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666

Query: 353  SLPVSRPISPSPSAILE 369
                  P    P+A+ E
Sbjct: 1667 QASKGLPAKKGPTALKE 1683


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 64/248 (25%), Positives = 93/248 (37%), Gaps = 33/248 (13%)

Query: 1717 VPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGK--QSKLQDPR 1774
            +P+  P A    TS P AS +G    P  +  P P+S+  R     +PG   Q  L+   
Sbjct: 70   IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129

Query: 1775 QYRQANGSAKK-------SGGDFKPTSPSLPASKIPAL---SPSSGKSSSLPSSSGDSSN 1824
            +   A G A +       S G  + TS   P +  PA+   S ++G    LP  +   S 
Sbjct: 130  EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA--PSA 187

Query: 1825 LPNPPATKP-SIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQS- 1882
             P PP   P    S+     T  P+ +A   PS   G  +  S + +     LS   +S 
Sbjct: 188  RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247

Query: 1883 QNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQN-------GSSSKAT 1935
             + R  P      S P P          KG + +  P +T  +           SS  AT
Sbjct: 248  PSARGTPRAPAHPSQPKP----------KGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297

Query: 1936 PSTAKETS 1943
            PS +   S
Sbjct: 298  PSPSAPPS 305



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 63/222 (28%), Positives = 82/222 (36%), Gaps = 47/222 (21%)

Query: 1707 AQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSG-APQTSRMPVPMSAKNRPGTLDKPG 1765
            A  A PRP   P EGP       S+ SAS   ++  +P   R P       RP +     
Sbjct: 184  APSARPRP---PTEGPRK-----SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235

Query: 1766 KQSKLQDP-RQYRQANGSAKKSGGDFKPTSPSLPASK-----------IPALSPSSGKSS 1813
              + L  P R    A G+ +      +P    L A +            PAL P S    
Sbjct: 236  SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295

Query: 1814 SLPSSSGDSS--------NLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQ 1865
            + PS S   S         LP+PPAT PS A+  L   T    H  S +PS     L   
Sbjct: 296  ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH--SFLPSPPLSPL--- 350

Query: 1866 SLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLN 1907
                       +  PQ+    A PPL    +PPSP +S  L+
Sbjct: 351  ----------ATPPPQAPPALALPPL---QAPPSPPASPPLS 379



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 51/207 (24%), Positives = 74/207 (35%), Gaps = 27/207 (13%)

Query: 1709 EASPRPLLVPDEGPTALEPPTSIP-SASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQ 1767
            +A P   L P + P +  PP S P S     S  AP    + +  +  + P +   P  Q
Sbjct: 356  QAPPALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS---PPVQ 410

Query: 1768 SKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPN 1827
            +    P     +  +   S       +P L     P  SP    S++ P  +      P 
Sbjct: 411  APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470

Query: 1828 ------PPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQ 1881
                  PP   P++A+ PL     PPA      P   + SL    L           +P 
Sbjct: 471  LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA----------TPP 520

Query: 1882 SQNGRAPPPLS--FSSSPPSPASSVSL 1906
             Q   APP L+      PPSP +S +L
Sbjct: 521  PQ---APPVLAAPLLQVPPSPPASPTL 544



 Score = 35.0 bits (79), Expect = 0.71
 Identities = 52/184 (28%), Positives = 66/184 (35%), Gaps = 33/184 (17%)

Query: 1718 PDEGPTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYR 1777
            P   P A  PP + P+ +       P     P P+S       L  P  Q+         
Sbjct: 345  PPLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSP------LATPSPQAPNALAVHLL 397

Query: 1778 QANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSI-- 1835
            QA  S   S     P SP  PAS  P +SPS+   S  P S      L  PP   P    
Sbjct: 398  QAPFSPPPSPPVQAPFSP--PAS--PPVSPSATPPSQAPPS------LAAPPLQVPPSPP 447

Query: 1836 ASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSS 1895
            AS P+SP   PP  +    P ++   L+                PQ+    A PPL    
Sbjct: 448  ASPPMSPSATPPPQAP---PPLAAPPLQLAKP-----------PPQAPPALATPPLQALP 493

Query: 1896 SPPS 1899
            SPP+
Sbjct: 494  SPPA 497



 Score = 34.7 bits (78), Expect = 0.93
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 13/84 (15%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTP--VPHSMPPSPSRIPYGGTRSMVV-------PGNAT 345
           P +  P S A PP  +P SPP++P   P + PP  +  P       +        P  AT
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486

Query: 346 IPRDRISSLPVS----RPISPSPS 365
            P   + S P S     P SPS S
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSAS 510



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 14/83 (16%)

Query: 295 PGAPRPGSTAHPPHAIPNS------------PPSTPV--PHSMPPSPSRIPYGGTRSMVV 340
           P +P     A P    PN+            PPS PV  P S P SP   P     S   
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432

Query: 341 PGNATIPRDRISSLPVSRPISPS 363
           P  A  P     S P S P+SPS
Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPS 455



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 37/127 (29%), Positives = 53/127 (41%), Gaps = 17/127 (13%)

Query: 995  QANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRR 1054
            QA  + + P L++PP+    P   AP          P++     +L     P PPPPP R
Sbjct: 522  QAPPVLAAPLLQVPPSPPASPTLQAPRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSR 578

Query: 1055 SYLPGSGLTTTRSGDVVYTGRKENITA---KASSEDAGPSPQTRATKYPAEEPA----SA 1107
            S  P S    T SG  +  G   + T+   +    D+GP     A+  P  E A    +A
Sbjct: 579  S--PSS----TLSGPDL-AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 631

Query: 1108 WTPSPPP 1114
            W+  P P
Sbjct: 632  WSRGPAP 638



 Score = 31.6 bits (70), Expect = 7.9
 Identities = 26/82 (31%), Positives = 29/82 (35%), Gaps = 15/82 (18%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTP--------------VPHSMPPSPSRIPYGGTRSMVV 340
           P AP P  +A P      SPP+TP                HS  PSP   P         
Sbjct: 300 PSAP-PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358

Query: 341 PGNATIPRDRISSLPVSRPISP 362
           P  A  P     S P S P+SP
Sbjct: 359 PALALPPLQAPPSPPASPPLSP 380


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 67/317 (21%), Positives = 120/317 (37%), Gaps = 24/317 (7%)

Query: 1541 TELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTL 1600
            +E+++ S    P      E+  DD    P+++ +   P +      +      KT  K  
Sbjct: 901  SEISEASEEKRPRPSTPAEEDEDD----PEQEKEAGEPGRPGTKPPKRDEERGKTQGKHR 956

Query: 1601 QVVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRK 1660
            +    + E E+ + +   E    +    + ++  E  V   ++ +  S      +D   K
Sbjct: 957  KSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSK 1016

Query: 1661 -NTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPD 1719
             + Y   D    +    E++ S  S  +   +S SS+  S + SS   +E   RP  +P 
Sbjct: 1017 CSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPS 1076

Query: 1720 EGPTALEPPTSIPSASR----KGSSGAPQTSRMPVPMSAKNRP-GTLDKPGKQSKLQDPR 1774
              P   E P   P+       +  +G+P T  +P   ++  RP G  ++    + L+ P 
Sbjct: 1077 ASPPPREVPVPTPAPVEVPVPERVAGSPVTP-LPEQEASPARPAGPTEESPPSAPLRPPE 1135

Query: 1775 QYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPS 1834
                A   A     D +P+SP      IP L P   +  ++  S+ +    P PP   P 
Sbjct: 1136 P--PAGPPAPAPRPDERPSSP------IPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPP 1187

Query: 1835 IASNPLSPQTGPPAHSA 1851
             A  P     GP +  A
Sbjct: 1188 QAKFP-----GPASRKA 1199



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 27/99 (27%), Positives = 40/99 (40%)

Query: 1726 EPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKK 1785
            + P+S    + + S G P TSR   P S  +   +          +    Y+ A      
Sbjct: 255  DTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHF 314

Query: 1786 SGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSN 1824
            S      T+ +  A+   A + SS  SSSL SSS  SS+
Sbjct: 315  SASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSS 353



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 44/161 (27%), Positives = 65/161 (40%), Gaps = 18/161 (11%)

Query: 1755 KNRPGTLDKPGKQSKLQDPRQYRQANGSAK-----KSGGDFKPTSPSLPASKIPALSPSS 1809
            ++R   +D   K++++ D     +++ S+K      S G+   TS S  +S   + S SS
Sbjct: 988  EDREEAVDTTKKETEVSDGED-EESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSS 1046

Query: 1810 GKSSSLPSSSGDSSNLPNP-----PATKPSIASNPLSPQTGPPAHSASLIPSVSNGS--- 1861
              SSS  SSS   S+  +      PA  PS +  P       PA     +P    GS   
Sbjct: 1047 SSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVT 1106

Query: 1862 -LKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPA 1901
             L  Q  +          SP S   R P P    + PP+PA
Sbjct: 1107 PLPEQEASPARPAGPTEESPPSAPLRPPEP---PAGPPAPA 1144



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 38/163 (23%), Positives = 54/163 (33%), Gaps = 38/163 (23%)

Query: 1028 EDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSED 1087
            E S  ++QD      ++PPP PP       PG G                          
Sbjct: 416  EPSRPTDQDYRPPASEAPPPEPPE------PGGG-----------------------GGG 446

Query: 1088 AGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKI-MAELQAFQKCSFM 1146
             GPSP+    +      + A + SP P TT+ S    +      +I M   +   K SF+
Sbjct: 447  GGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFL 506

Query: 1147 DVNSNSHAEPSRADSHVKDTRS--------GATVPPKEKKNLE 1181
              ++    E S      +DT S        G   PP    N E
Sbjct: 507  ASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFE 549



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 12/18 (66%), Positives = 14/18 (77%)

Query: 1043 KSPPPPPPPPRRSYLPGS 1060
            + PPPPPPPP R+Y P S
Sbjct: 1402 RPPPPPPPPPPRAYEPRS 1419



 Score = 32.0 bits (71), Expect = 6.1
 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 38/160 (23%)

Query: 1732 PSASRKGSSGAPQTSRMPVPM----SAKNRPGTL--DKPGKQSKLQDPRQYRQAN----- 1780
            P++  +  S AP+T+   VP     S  +R   L  ++  K S L    +  + N     
Sbjct: 462  PASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVL 521

Query: 1781 -----GSAKKSGGDFKPTSPSLPASKIPALSPS--------------SGKSSSLPSSSGD 1821
                 GS   SG    P +P    +    ++P+              +G++ + P SSGD
Sbjct: 522  GARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGD 581

Query: 1822 SSNL--------PNPPATKPSIASNPLSPQTGPPAHSASL 1853
               +        P P  T P     P  P   PP + ASL
Sbjct: 582  DMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASL 621


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 116/587 (19%), Positives = 226/587 (38%), Gaps = 67/587 (11%)

Query: 1070 VVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEE 1129
            VV    KE +  +  +E+      T+ T+   EE                +K+EE +EEE
Sbjct: 446  VVEKSEKETVIVEEQTEE------TQVTEEVTEEEEK------------EAKEEEGKEEE 487

Query: 1130 GDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRK 1189
            G +   E +  ++ +       + +    A S VK+        P E K+ E   ++  K
Sbjct: 488  GGE-EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS----PAEAKSPE---KEEAK 539

Query: 1190 SDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNM 1249
            S  E ++ P+         A  P +    E+  E + S A   S  K +   KE + S  
Sbjct: 540  SPAEVKS-PEKAKSPAKEEAKSPPEAKSPEK--EEAKSPAEVKSPEKAKSPAKEEAKSPA 596

Query: 1250 SLLRDSRNYSQETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEM 1309
               +           +A       SP+++E    +++   + +   T+ +  +  K K  
Sbjct: 597  EA-KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655

Query: 1310 EKQNTD-----KCHVSSHTRLTESSVHDFKTEDQ--EVITTDFGQVVLRPKEARHANVNP 1362
            EK+        K  V +  +  E +    K E +  E   +   +    P++A+ + V  
Sbjct: 656  EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK-SPVKE 714

Query: 1363 NEDGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEM 1422
                   + SP +E A T   A        +   S E     ++  E  +T+++ + +  
Sbjct: 715  EAKSPEKAKSPVKEEAKTPEKA---KSPVKEEAKSPEK----AKSPEKAKTLDVKSPEAK 767

Query: 1423 TPRQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEE 1482
            TP +E  +   P    DK P         +++S  K  S + E+     + +  +E+++ 
Sbjct: 768  TPAKE--EARSPA---DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS 822

Query: 1483 EEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTE 1542
              +EE     V+     + + ++ AP   +T ++ ++K +  +   E   P  +E     
Sbjct: 823  PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE-EAPKKEAPKPKVEEKKEPA 881

Query: 1543 LNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQV 1602
            + K         E K E+A D        K K   P+K+  A  + ++   K  +KT   
Sbjct: 882  VEK---PKESKVEAKKEEAED--------KKKVPTPEKEAPAKVE-VKEDAKPKEKT--- 926

Query: 1603 VVYEEEEEDGTLKQ-HKEAKRFEIARSQPEDTPENTVRRQEQPSIES 1648
             V ++E +D   K+  K A++ E A  + +   E   + +E+P  E+
Sbjct: 927  EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEA 973



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 149/752 (19%), Positives = 274/752 (36%), Gaps = 100/752 (13%)

Query: 657  RLQLQQMRQLQLQNQELLRAMMK-----KAELEISGKVMETMKRLEDPVQRQRVLVEQER 711
            R++L ++ +    N + +R+  +     + +L+     +E +K  +D ++RQR  +E   
Sbjct: 294  RVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRH 353

Query: 712  QKYLHEEEKIVKKL-CELEDFVEDLKKDSTAASRLVTLK---DVEDGAFLLRQVGEAVAT 767
            Q  +   ++ +++L  EL +   ++         L+ +K   D+E  A+     GE    
Sbjct: 354  QADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRI 413

Query: 768  LKGEFP-TLQNKMRAI------LRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTML--- 817
              G  P +L   +  I      ++++ E    + E+  K   +++     T V   +   
Sbjct: 414  GFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEE 473

Query: 818  ----------------RRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQ 861
                                 +G  + T +  A +  + EK   + V +  +  A     
Sbjct: 474  EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533

Query: 862  PFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQ-NLPHVASSPAVP 920
                  +P + KS     S      A+S P    P +      +PA+   P  A SPA  
Sbjct: 534  EKEEAKSPAEVKSPEKAKSPAK-EEAKSPPEAKSPEKEEAK--SPAEVKSPEKAKSPA-K 589

Query: 921  QEATSTLQMSQAPQSPQIPMNGSAM-----QSLFIEEIHS---VSAKNRAVSIEKAEKKW 972
            +EA S  + +++P+  + P+   A      +S   EE  S   V +  +A S  K E K 
Sbjct: 590  EEAKSPAE-AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648

Query: 973  EEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPN 1032
             EK ++ +    K  EK     +A      P     P        +     V+    SP 
Sbjct: 649  PEKAKSPEKEEAKSPEKAKSPVKAEAKS--PEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706

Query: 1033 SEQDLEKLGGKSPPPPPPP-------PRRSYLP----GSGLTTTRSGDVVYTGRKENITA 1081
              +   K   KSP     P       P ++  P           +S +   T   ++  A
Sbjct: 707  KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA 766

Query: 1082 KASSEDAGPSPQTRATKYP--AEEPASAWTPSPPPVTTSSSKDEEEEEEE---GDKIMAE 1136
            K  +++   SP   A K+P  A+ P      SP    +   +D +  E+E    +++ + 
Sbjct: 767  KTPAKEEARSP---ADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823

Query: 1137 LQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYEN 1196
            ++  +K   + V      EP +     K   +  T   K+ K  E   ++  K  VE + 
Sbjct: 824  VKEEEKPQEVKVK-----EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878

Query: 1197 GPQMEFQKVTTGAVRPSDP--------PKWERGMENSISDASRTSEYKTEIIMKENSISN 1248
             P +E  K +    +  +         P+ E   +  + + ++  E KTE+  KE     
Sbjct: 879  EPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEP---- 933

Query: 1249 MSLLRDSRNYSQETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKT-- 1306
                 D     + + P         +P E +  K  K    +   P TE +     KT  
Sbjct: 934  -----DDAKAKEPSKPAEK---KEAAP-EKKDTKEEKAKKPEEK-PKTEAKAKEDDKTLS 983

Query: 1307 KEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQ 1338
            KE  K   +K   SS T   +S   +  TED+
Sbjct: 984  KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 98/531 (18%), Positives = 193/531 (36%), Gaps = 60/531 (11%)

Query: 1305 KTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNE 1364
            K K +EK   +   V   T  T+ +    + E++E    +        KE         E
Sbjct: 443  KIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEE-------GKEEEGGEEEEAE 495

Query: 1365 DGESSSSSPTEENAATDNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTP 1424
             GE  + SP  E AA+       +    +  S  E      ++ +    V    + +   
Sbjct: 496  GGEEETKSPPAEEAASPEKEAK-SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPA 554

Query: 1425 RQEGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEE 1484
            ++E     +      K P       P +++S  K  S   EE     E    E+     +
Sbjct: 555  KEEAKSPPEA-----KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609

Query: 1485 EEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLATE-TRNPGGQEMNRTEL 1543
            EE    +  +    S +  +  +P  +++ ++ ++ ++  + + E  ++P  +E    E 
Sbjct: 610  EEAKSPAEAK----SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665

Query: 1544 NKF---SHVDSPN---SECKGEDATDDQFESPKKKF-----KFKFPKKQLAALTQAIRTG 1592
             K    +   SP    S  K E  + ++ +SP K+      K K P K+ A   +  ++ 
Sbjct: 666  AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725

Query: 1593 TKTGKKTLQVV---VYEEEEEDGTLKQHKEAKRFEI------------ARSQPEDTPENT 1637
             K   KT +     V EE +     K  ++AK  ++            ARS  +  PE  
Sbjct: 726  VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785

Query: 1638 ---VRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENT----ISEMSPKALVD 1690
               V+ + +   ++ SP+    +  +      + ++  +K+ E      + E   KA  +
Sbjct: 786  KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845

Query: 1691 TSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPPTSIPSASRKGSSGAPQTSRMPV 1750
             + ++ +      S   +E +P+      +     EP    P  S+  +       +  V
Sbjct: 846  KAPATPKTEEKKDSK--KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903

Query: 1751 PMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASK 1801
            P   K  P  ++       +++  + ++    AKK   D K   PS PA K
Sbjct: 904  PTPEKEAPAKVE-------VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 57/290 (19%), Positives = 108/290 (37%), Gaps = 17/290 (5%)

Query: 1604 VYEEEEEDGTLKQHKEAK--RFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKN 1661
            V EEEE++   ++ KE +    E A    E+T          P  E+ SP+    E  K+
Sbjct: 470  VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK---EEAKS 526

Query: 1662 TYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEG 1721
                    ++  K      S    K+       S  +  A S    +  SP  +  P++ 
Sbjct: 527  PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE--AKSPEKEEAKSPAEVKSPEKA 584

Query: 1722 PTALEPPTSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANG 1781
             +  +     P+ ++     +P+ ++ PV   AK+ P     P K+ + + P + +    
Sbjct: 585  KSPAKEEAKSPAEAK-----SPEKAKSPVKEEAKS-PAEAKSPVKE-EAKSPAEVKSPEK 637

Query: 1782 SAKKSGGDFKPTSPSLPASKIPALSPSSGKSS-SLPSSSGDSSNLP-NPPATKPSIASNP 1839
            +   +  + K    +    K  A SP   KS     + S + +  P    A  P  A +P
Sbjct: 638  AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697

Query: 1840 LSPQTGPPAHSASLIPSVSNGSLKFQS-LTHTGKGHHLSFSPQSQNGRAP 1888
            +  +   P  + S +   +    K +S +    K    + SP  +  ++P
Sbjct: 698  VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 171/867 (19%), Positives = 285/867 (32%), Gaps = 111/867 (12%)

Query: 1085 SEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIM---------- 1134
            S D   +P     ++     +S WTP  P  +TS S+      + G              
Sbjct: 85   SADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGT 144

Query: 1135 -AELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVE 1193
             +  Q   + S+ +  S+S  +      H K +RS +   P+   +L   H     +D  
Sbjct: 145  NSSGQRHDRESYNNSGSSSRKKGQHGSEHSK-SRSSSPGKPQAVSSLNSSHSRSHGND-- 201

Query: 1194 YENGPQMEFQKVTTGAVRPSDPP-KWERGMENSISDASR-TSEYKTEIIMKENSISNMSL 1251
                      K    +  P DP   W+       S     T  +   ++ K NS     +
Sbjct: 202  -------HHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNS-----M 249

Query: 1252 LRDSRNYSQETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEK 1311
            L+    Y              + P++ + +   K+S   YS     N      + K   K
Sbjct: 250  LQKPTAY--------------VRPMDGQESMEPKLSSEHYSSQSHGNSMT---ELKPSSK 292

Query: 1312 QNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSS 1371
             +  K  + S   L  S+  D    D+  I  +       P  A H    P +   S   
Sbjct: 293  AHLTKLKIPSQP-LDASASGDVSCVDE--ILKEMTHSWPPPLTAIHT---PCKTEPSKFP 346

Query: 1372 SPTEENAAT-----DNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQ 1426
             PT+E+  +     +   +  ++T+    S   + D +     +      D  K M PR 
Sbjct: 347  FPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTM-PRS 405

Query: 1427 EGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEE 1486
                N +P     +       D   D  S++   S      D E E    + +  E  + 
Sbjct: 406  TPGSNSEPSHHNSEGA-----DNSRDDSSSHSG-SESSSGSDSESESSSSDSEANEPSQS 459

Query: 1487 ENGDSVVQNNNTSQMSH--KKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTELN 1544
             + +      N  Q+ +   KV P  +     V++       +++     G+E      N
Sbjct: 460  ASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIP----SSQGYKKEGREQGTG--N 513

Query: 1545 KFSHVDSP---NSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQ 1601
             ++    P   +S   G D+   Q  S   + + K P  Q  + TQ    G K  KK  +
Sbjct: 514  SYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPA-QSDSTTQRRTVGKKQPKKAEK 572

Query: 1602 VVVYEEEEEDGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKN 1661
                  EE  G LK   E    ++A S P    +   +   +P+I+  S  S      K 
Sbjct: 573  AAA---EEPRGGLKIESETP-VDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKK 628

Query: 1662 TYRTLDSLEQTIKQLENTISEMS---------PKALVDTSCSSNRDSVASSSHIAQEASP 1712
             Y++     Q  +++  T +  S         P +       SNR  V  SS   +++  
Sbjct: 629  KYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFF 688

Query: 1713 RPLLVPDEGPTALEPPTSIPSASRK-----------GSSGAPQTSRMPVPMSAKNRPGTL 1761
            R  +        L  P S P                   G P     P     KN P   
Sbjct: 689  RQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP--- 745

Query: 1762 DKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASK---IPALSPSSGKSSSLPSS 1818
            +K  ++++ Q   +         K+  D + +    P ++        PSS + SS  S+
Sbjct: 746  EKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA 805

Query: 1819 SGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSN------GSLKFQSLTHTGK 1872
            + +   LP+P    PS                +S + S SN      GS K  S T   K
Sbjct: 806  AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQK 865

Query: 1873 GHHLSFSPQSQNGRAPPPLSFSSSPPS 1899
                  S  S+  +   P S S+ PPS
Sbjct: 866  KTEGKTSSSSKEVKEKAPSSSSNCPPS 892



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 73/350 (20%), Positives = 129/350 (36%), Gaps = 73/350 (20%)

Query: 1015 PRGDAPVDK---VELSEDSPNSEQDLEKLGGKSP-------PPPPPPPRRSYLPGSGLTT 1064
            PRG   ++    V+L+   P+S       G + P         P P   +     +  ++
Sbjct: 578  PRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSS 637

Query: 1065 TRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEE 1124
             +S +++ T    + ++  S E     P ++  KYP     S  TP  P      S  EE
Sbjct: 638  QKSREIIET----DTSSSDSDESESLPPSSQTPKYPE----SNRTPVKP------SSVEE 683

Query: 1125 EEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGA----TVPPK-EKKN 1179
            E+     ++ + ++  +  S +    + +    + D ++     G     T PPK EKKN
Sbjct: 684  EDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKN 743

Query: 1180 LEFFH--EDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWE----------RGMENSIS 1227
            +   H  E  +++  +  N  + + +         S  PK E             E+S  
Sbjct: 744  VPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQ 803

Query: 1228 DASRTSEY-------------KTEIIMKENSISNMSLLRDSRNYSQETVPKASFGFSGIS 1274
             A++  +              KTE   ++ +IS  S L+ S N ++ET        SG S
Sbjct: 804  SAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKET--------SGSS 855

Query: 1275 PLEDEINKGSKISGLQYSIPDTENQTLNYGK-TKEMEKQNTDKCHVSSHT 1323
                  +K  K          TE +T +  K  KE    ++  C  S+ T
Sbjct: 856  KNSSSTSKQKK----------TEGKTSSSSKEVKEKAPSSSSNCPPSAPT 895



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 119/675 (17%), Positives = 242/675 (35%), Gaps = 135/675 (20%)

Query: 1023 KVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK 1082
            K+  SEDS + EQD +K   +S P     P  S+    G   +R     ++G + +  + 
Sbjct: 385  KLSSSEDS-DGEQDCDKTMPRSTPGSNSEP--SHHNSEGADNSRDDSSSHSGSESSSGSD 441

Query: 1083 ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQK 1142
            + SE +    +       A EP+ + +P P P  T+                     +Q 
Sbjct: 442  SESESSSSDSE-------ANEPSQSASPEPEPPPTNK--------------------WQL 474

Query: 1143 CSFMD-VNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQME 1201
             ++++ VN +  +  S  DS++          P  +   +   E    +     +GP   
Sbjct: 475  DNWLNKVNPHKVSPASSVDSNI----------PSSQGYKKEGREQGTGNSYTDTSGP--- 521

Query: 1202 FQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQE 1261
              K T+ A    D    ++G E+      + S  +++   +  ++      +  +  ++E
Sbjct: 522  --KETSSATPGRDSKTIQKGSES--GRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEE 577

Query: 1262 TVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYGKTKEMEKQNTDKCHVSS 1321
              P+        +P++           L  S+P + ++    G  K   K+ +      +
Sbjct: 578  --PRGGLKIESETPVD-----------LASSMPSSRHKAATKGSRKPNIKKESKSSPRPT 624

Query: 1322 HTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEENAATD 1381
              +    S      + +E+I TD                + ++  ES S  P+ +     
Sbjct: 625  AEKKKYKSTSKSSQKSREIIETD---------------TSSSDSDESESLPPSSQTPKYP 669

Query: 1382 NIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQEGTDNEDPVVCLDKK 1441
                    T V+  S  E      Q+        ++ ++ ++P  E  D    +V +D  
Sbjct: 670  E----SNRTPVKPSSVEEEDSFFRQR----MFSPMEEKELLSPLSEPDDRYPLIVKIDLN 721

Query: 1442 PVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQM 1501
             +  I  +P      YK      E    + E+  + EK   E +++  + V   +N  + 
Sbjct: 722  LLTRIPGKP------YK------ETEPPKGEKKNVPEKHTREAQKQASEKV---SNKGKR 766

Query: 1502 SHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGEDA 1561
             H                K++  + A+E++ P  ++ N        H  S N E   + A
Sbjct: 767  KH----------------KNEDDNRASESKKPKTEDKNSA-----GHKPSSNRESSKQSA 805

Query: 1562 T--DDQFESPKKKFKFKFPK------KQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGT 1613
                D   SP      K PK      K+  + + ++++ + + K+T        +    T
Sbjct: 806  AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG----SSKNSSST 861

Query: 1614 LKQHK-EAKRFEIARSQPEDTPENTVR-RQEQPSIESTSPISRTDEIRKNTYRTLDSLEQ 1671
             KQ K E K    ++   E  P ++       P+++S+ P  RT  +  +   + D   Q
Sbjct: 862  SKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKP-RRTKLVFDDRNYSADHYLQ 920

Query: 1672 TIKQLENTISEMSPK 1686
              K+L++    +S +
Sbjct: 921  EAKKLKHNADALSDR 935


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.125    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,316,483
Number of Sequences: 37866
Number of extensions: 4769815
Number of successful extensions: 48046
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 1666
Number of HSP's that attempted gapping in prelim test: 31756
Number of HSP's gapped (non-prelim): 15402
length of query: 1943
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1826
effective length of database: 13,817,196
effective search space: 25230199896
effective search space used: 25230199896
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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