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Search of human proteins with 50726960
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50726960 phosphatidylinositol (4,5) bisphosphate
5-phosphatase, A [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 1312 0.0
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 387 e-107
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 337 2e-92
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 337 2e-92
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 186 7e-47
gi|26190608 synaptojanin 2 [Homo sapiens] 179 9e-45
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 174 3e-43
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 174 3e-43
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 162 1e-39
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 162 1e-39
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 160 4e-39
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 159 1e-38
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 120 5e-27
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 120 5e-27
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 109 7e-24
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 106 7e-23
gi|239752992 PREDICTED: hypothetical protein XP_002345322 [Homo ... 48 3e-05
gi|239747550 PREDICTED: hypothetical protein XP_002347647 [Homo ... 48 3e-05
gi|239741424 PREDICTED: hypothetical protein XP_002342197 [Homo ... 48 3e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 45 3e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 44 3e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 44 5e-04
gi|119943086 Tax1 (human T-cell leukemia virus type I) binding p... 44 5e-04
gi|21361682 Tax1 (human T-cell leukemia virus type I) binding pr... 44 5e-04
gi|41281612 zinc finger protein 828 [Homo sapiens] 44 5e-04
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 43 8e-04
gi|73858559 proline/serine-rich coiled-coil 1 isoform c [Homo sa... 43 0.001
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 43 0.001
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 42 0.002
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 42 0.002
>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase,
A [Homo sapiens]
Length = 638
Score = 1312 bits (3396), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MEGQSSRGSRRPGTRAGLGSLPMPQGVAQTGAPSKVDSSFQLPAKKNAALGPSEPRITVV 60
MEGQSSRGSRRPGTRAGLGSLPMPQGVAQTGAPSKVDSSFQLPAKKNAALGPSEPRITVV
Sbjct: 1 MEGQSSRGSRRPGTRAGLGSLPMPQGVAQTGAPSKVDSSFQLPAKKNAALGPSEPRITVV 60
Query: 61 TWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKDALFTDQWSELFM 120
TWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKDALFTDQWSELFM
Sbjct: 61 TWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKDALFTDQWSELFM 120
Query: 121 DALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLA 180
DALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLA
Sbjct: 121 DALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLA 180
Query: 181 AFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRI 240
AFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRI
Sbjct: 181 AFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRI 240
Query: 241 ESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYD 300
ESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYD
Sbjct: 241 ESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYD 300
Query: 301 TSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQF 360
TSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQF
Sbjct: 301 TSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQF 360
Query: 361 LLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVA 420
LLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVA
Sbjct: 361 LLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVA 420
Query: 421 YVWAKHEDVDGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQISLPSSELAS 480
YVWAKHEDVDGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQISLPSSELAS
Sbjct: 421 YVWAKHEDVDGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQISLPSSELAS 480
Query: 481 SSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRG 540
SSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRG
Sbjct: 481 SSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRG 540
Query: 541 ASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLET 600
ASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLET
Sbjct: 541 ASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLET 600
Query: 601 VDPGGGGSWGPDREALAPNSLSPSPQGHRGLEEGGLGP 638
VDPGGGGSWGPDREALAPNSLSPSPQGHRGLEEGGLGP
Sbjct: 601 VDPGGGGSWGPDREALAPNSLSPSPQGHRGLEEGGLGP 638
>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
sapiens]
Length = 448
Score = 387 bits (993), Expect = e-107
Identities = 198/426 (46%), Positives = 262/426 (61%), Gaps = 7/426 (1%)
Query: 51 GPSEPRIT--VVTWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKD 108
GP R++ VVTWNV +A PP D++ LL L + + D+ IGLQE+NS + L D
Sbjct: 8 GPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLN--LDIYVIGLQELNSGIISLLSD 65
Query: 109 ALFTDQWSELFMDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGY 168
A F D WS MD L P +F+ VS VRMQG++LL+FAKY HLP+++ + T T TGL GY
Sbjct: 66 AAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGY 125
Query: 169 WGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHD 228
WGNKGGV++ L +G+ + +NCHLP H+ QR ++F IL +Q +G ILDHD
Sbjct: 126 WGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHD 185
Query: 229 LVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAP 288
L+ WFGD+NFRIE + LHFV+ +I + LWEKDQL++AK P+L+ FQEG L F P
Sbjct: 186 LIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPP 245
Query: 289 TFKFDVGTNKYDTSAKKRKPAWTDRILWKVK-APGGGPSPSGRKSHRLQVTQHSYRSHME 347
T+KFD +N YDTS KKRKPAWTDRILW++K P GP + ++ Y SHM
Sbjct: 246 TYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMT 305
Query: 348 YTVSDHKPVAAQFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGL 407
Y +SDHKPV+ F L+ PL+ L D W +V Y + F S WDWIGL
Sbjct: 306 YGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGL 365
Query: 408 YRVGFRHCKDYVAYVWAKHEDV--DGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGI 465
Y+VG R DYV+Y W V N QV ++P +F+L YYS++ ++GI
Sbjct: 366 YKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGI 425
Query: 466 TEPFQI 471
+ PFQI
Sbjct: 426 SRPFQI 431
>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 337 bits (864), Expect = 2e-92
Identities = 167/355 (47%), Positives = 221/355 (62%), Gaps = 3/355 (0%)
Query: 120 MDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRL 179
MD L P +F+ VS VRMQG++LL+FAKY HLP+++ + T T TGL GYWGNKGGV++ L
Sbjct: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
Query: 180 AAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFR 239
+G+ + +NCHLP H+ QR ++F IL +Q +G ILDHDL+ WFGD+NFR
Sbjct: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
Query: 240 IESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKY 299
IE + LHFV+ +I + LWEKDQL++AK P+L+ FQEG L F PT+KFD +N Y
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
Query: 300 DTSAKKRKPAWTDRILWKVK-APGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAA 358
DTS KKRKPAWTDRILW++K P GP + ++ Y SHM Y +SDHKPV+
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
Query: 359 QFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDY 418
F L+ PL+ L D W +V Y + F S WDWIGLY+VG R DY
Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
Query: 419 VAYVWAKHEDV--DGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQI 471
V+Y W V N QV ++P +F+L YYS++ ++GI+ PFQI
Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQI 355
>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 337 bits (864), Expect = 2e-92
Identities = 167/355 (47%), Positives = 221/355 (62%), Gaps = 3/355 (0%)
Query: 120 MDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRL 179
MD L P +F+ VS VRMQG++LL+FAKY HLP+++ + T T TGL GYWGNKGGV++ L
Sbjct: 1 MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60
Query: 180 AAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFR 239
+G+ + +NCHLP H+ QR ++F IL +Q +G ILDHDL+ WFGD+NFR
Sbjct: 61 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120
Query: 240 IESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKY 299
IE + LHFV+ +I + LWEKDQL++AK P+L+ FQEG L F PT+KFD +N Y
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
Query: 300 DTSAKKRKPAWTDRILWKVK-APGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAA 358
DTS KKRKPAWTDRILW++K P GP + ++ Y SHM Y +SDHKPV+
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
Query: 359 QFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDY 418
F L+ PL+ L D W +V Y + F S WDWIGLY+VG R DY
Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300
Query: 419 VAYVWAKHEDV--DGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQI 471
V+Y W V N QV ++P +F+L YYS++ ++GI+ PFQI
Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQI 355
>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
[Homo sapiens]
Length = 913
Score = 186 bits (471), Expect = 7e-47
Identities = 107/308 (34%), Positives = 161/308 (52%), Gaps = 30/308 (9%)
Query: 61 TWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKR---LKDALFTDQWSE 117
T+NV P + L L + D+ +G QE++ L+K D ++W +
Sbjct: 271 TYNVNGQSPKE----CLRLWLSNGIQAPDVYCVGFQELD--LSKEAFFFHDTPKEEEWFK 324
Query: 118 LFMDALGP-FNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVS 176
+ L P + V +R+ G++LLL+ K H ++ +V+ + TG+ G GNKGGV+
Sbjct: 325 AVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVA 384
Query: 177 VRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQ----GILDHDLVFW 232
+R +C +N HL AH+++ E+R +++ I S QF P I +HD++ W
Sbjct: 385 IRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILW 444
Query: 233 FGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKF 292
GDLN+RIE D+ VK I+ L+ DQL + + +GF EG L F PT+K+
Sbjct: 445 LGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKY 504
Query: 293 DVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSD 352
D G++ +DTS K R PAW DRILWK K +TQ SY+SHM SD
Sbjct: 505 DTGSDDWDTSEKCRAPAWCDRILWKGK----------------NITQLSYQSHMALKTSD 548
Query: 353 HKPVAAQF 360
HKPV++ F
Sbjct: 549 HKPVSSVF 556
>gi|26190608 synaptojanin 2 [Homo sapiens]
Length = 1496
Score = 179 bits (453), Expect = 9e-45
Identities = 113/334 (33%), Positives = 167/334 (50%), Gaps = 35/334 (10%)
Query: 56 RITVVTWNVG-----------TAMPPDDVTSLLHLGGG----DDSDGADMIAIGLQEVNS 100
RI + TWNV TA D + L G DDS AD+ A+G +E+
Sbjct: 531 RIAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDDSSPADIFAVGFEEMVE 590
Query: 101 MLNKRLKDALFTDQ--WSELFMDALG-PFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQ 157
+ + +A T++ W E A+ ++L++S ++ GV L +F + YH+PF+RDV
Sbjct: 591 LSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVA 650
Query: 158 TDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQ 217
D +TG+GG GNKG V +R CF+ HL A + ++R ++++ I Q+
Sbjct: 651 IDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEIT--QKLC 708
Query: 218 GPGAQGILDHDLVFWFGDLNFRIE-SYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPIL 276
P + + HD VFW GD N+RI+ +Y+ F + + +L E DQL + K++ I
Sbjct: 709 FPMGRNVFSHDYVFWCGDFNYRIDLTYEEVF--YFVKRQDWKKLLEFDQLQLQKSSGKIF 766
Query: 277 KGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRIL-WKVKAP-----------GGG 324
K F EG +NF PT+K+DVG+ YDTS K R PAWTDR+L W+ K P
Sbjct: 767 KDFHEGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSD 826
Query: 325 PSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAA 358
+ H Y E SDH+PV A
Sbjct: 827 LDVDTKVRHTWSPGALQYYGRAELQASDHRPVLA 860
>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
isoform b [Homo sapiens]
Length = 893
Score = 174 bits (440), Expect = 3e-43
Identities = 106/311 (34%), Positives = 157/311 (50%), Gaps = 26/311 (8%)
Query: 56 RITVVTWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLK-DALFTDQ 114
R V TWNV P + L+ D + D+ IG QE++ +++ +
Sbjct: 241 RFFVGTWNVNGQSPDSGLEPWLNC----DPNPPDIYCIGFQELDLSTEAFFYFESVKEQE 296
Query: 115 WSELFMDAL-GPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKG 173
WS L + V VR+ G++LL+FA+ ++RD+ T+ TG+ G GNKG
Sbjct: 297 WSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKG 356
Query: 174 GVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQ----GILDHDL 229
GV+VR C +N HL AH++ E+R +++ I + F P I+ H++
Sbjct: 357 GVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEV 416
Query: 230 VFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPT 289
V W GDLN+R+ D + VK I+ L +L + DQLN+ + F EG + F PT
Sbjct: 417 VIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPT 476
Query: 290 FKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYT 349
+K+D T+++D+S K R PAW DRILW+ V Q +YRSHME
Sbjct: 477 YKYDSKTDRWDSSGKCRVPAWCDRILWR----------------GTNVNQLNYRSHMELK 520
Query: 350 VSDHKPVAAQF 360
SDHKPV+A F
Sbjct: 521 TSDHKPVSALF 531
>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
Length = 901
Score = 174 bits (440), Expect = 3e-43
Identities = 106/311 (34%), Positives = 157/311 (50%), Gaps = 26/311 (8%)
Query: 56 RITVVTWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLK-DALFTDQ 114
R V TWNV P + L+ D + D+ IG QE++ +++ +
Sbjct: 241 RFFVGTWNVNGQSPDSGLEPWLNC----DPNPPDIYCIGFQELDLSTEAFFYFESVKEQE 296
Query: 115 WSELFMDAL-GPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKG 173
WS L + V VR+ G++LL+FA+ ++RD+ T+ TG+ G GNKG
Sbjct: 297 WSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKG 356
Query: 174 GVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQ----GILDHDL 229
GV+VR C +N HL AH++ E+R +++ I + F P I+ H++
Sbjct: 357 GVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEV 416
Query: 230 VFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPT 289
V W GDLN+R+ D + VK I+ L +L + DQLN+ + F EG + F PT
Sbjct: 417 VIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPT 476
Query: 290 FKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYT 349
+K+D T+++D+S K R PAW DRILW+ V Q +YRSHME
Sbjct: 477 YKYDSKTDRWDSSGKCRVPAWCDRILWR----------------GTNVNQLNYRSHMELK 520
Query: 350 VSDHKPVAAQF 360
SDHKPV+A F
Sbjct: 521 TSDHKPVSALF 531
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 162 bits (409), Expect = 1e-39
Identities = 175/646 (27%), Positives = 269/646 (41%), Gaps = 96/646 (14%)
Query: 52 PSEPRITVVTWNVG-------TAMPPDDVTSLL----HLGGGDD-----SDGADMIAIGL 95
P + R+ V TWNV A +T L L G + S D+ AIG
Sbjct: 569 PKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGF 628
Query: 96 QEVNSMLNKRLKDALFTDQ--WSELFMDALGPFN-FVLVSSVRMQGVILLLFAKYYHLPF 152
+E+ + + A T+Q W+ + N +VL++S ++ GV L +F + H PF
Sbjct: 629 EEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPF 688
Query: 153 LRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILS 212
+RDV D +TG+GG GNKG V++R+ LCF+ H A + ++R ++F I
Sbjct: 689 IRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIAR 748
Query: 213 LQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNT 272
F P + + HD VFW GD N+RI+ + VK I L DQL KN
Sbjct: 749 KLSF--PMGRMLFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGDQLINQKNA 805
Query: 273 WPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS 332
+ +GF EG + FAPT+K+D+ ++ YDTS K R PAWTDR+LW+ + P R +
Sbjct: 806 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRR-----KWPFDRSA 860
Query: 333 HRLQVTQHSYR-----------------SHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRL 375
L + S++ E SDH+PV A L+ + R
Sbjct: 861 EDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVA--LIDIDIFEVEAEERQ 918
Query: 376 EVADEWVR---PEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKH-EDVDG 431
+ E + P V +++ +++ L + + + + ED
Sbjct: 919 NIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMW 978
Query: 432 NTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEP--------------FQISLPSSE 477
T+ S ++ +G +L N +I I + P I+LPSS
Sbjct: 979 VTFLEGSSALNVLSLNGKELL-----NRTITIALKSPDWIKNLEEEMSLEKISIALPSST 1033
Query: 478 ----LASSSTDSSGTSSEGE-DDSTLEL-------LAPKSRS---PSPGKSKR-HRSRSP 521
L + ++ EG+ DD + E+ L P S S SP S R +SP
Sbjct: 1034 SSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSP 1093
Query: 522 GLAR--FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGP 579
++ P L +RPS R SR+P P S + S + ++ ++ P+ P
Sbjct: 1094 TISEGPVPSLPIRPS----RAPSRTPGPPSAQSSPIDAQPAT-----PLPQKDPAQPLEP 1144
Query: 580 WAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSP 625
PP P + PA P G S P R+ PSP
Sbjct: 1145 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSP 1190
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 162 bits (409), Expect = 1e-39
Identities = 175/646 (27%), Positives = 269/646 (41%), Gaps = 96/646 (14%)
Query: 52 PSEPRITVVTWNVG-------TAMPPDDVTSLL----HLGGGDD-----SDGADMIAIGL 95
P + R+ V TWNV A +T L L G + S D+ AIG
Sbjct: 569 PKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGF 628
Query: 96 QEVNSMLNKRLKDALFTDQ--WSELFMDALGPFN-FVLVSSVRMQGVILLLFAKYYHLPF 152
+E+ + + A T+Q W+ + N +VL++S ++ GV L +F + H PF
Sbjct: 629 EEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPF 688
Query: 153 LRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILS 212
+RDV D +TG+GG GNKG V++R+ LCF+ H A + ++R ++F I
Sbjct: 689 IRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIAR 748
Query: 213 LQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNT 272
F P + + HD VFW GD N+RI+ + VK I L DQL KN
Sbjct: 749 KLSF--PMGRMLFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGDQLINQKNA 805
Query: 273 WPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS 332
+ +GF EG + FAPT+K+D+ ++ YDTS K R PAWTDR+LW+ + P R +
Sbjct: 806 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRR-----KWPFDRSA 860
Query: 333 HRLQVTQHSYR-----------------SHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRL 375
L + S++ E SDH+PV A L+ + R
Sbjct: 861 EDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVA--LIDIDIFEVEAEERQ 918
Query: 376 EVADEWVR---PEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKH-EDVDG 431
+ E + P V +++ +++ L + + + + ED
Sbjct: 919 NIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMW 978
Query: 432 NTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEP--------------FQISLPSSE 477
T+ S ++ +G +L N +I I + P I+LPSS
Sbjct: 979 VTFLEGSSALNVLSLNGKELL-----NRTITIALKSPDWIKNLEEEMSLEKISIALPSST 1033
Query: 478 ----LASSSTDSSGTSSEGE-DDSTLEL-------LAPKSRS---PSPGKSKR-HRSRSP 521
L + ++ EG+ DD + E+ L P S S SP S R +SP
Sbjct: 1034 SSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSP 1093
Query: 522 GLAR--FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGP 579
++ P L +RPS R SR+P P S + S + ++ ++ P+ P
Sbjct: 1094 TISEGPVPSLPIRPS----RAPSRTPGPPSAQSSPIDAQPAT-----PLPQKDPAQPLEP 1144
Query: 580 WAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSP 625
PP P + PA P G S P R+ PSP
Sbjct: 1145 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSP 1190
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 160 bits (404), Expect = 4e-39
Identities = 179/672 (26%), Positives = 278/672 (41%), Gaps = 107/672 (15%)
Query: 52 PSEPRITVVTWNVG-------TAMPPDDVTSLL----HLGGGDD-----SDGADMIAIGL 95
P + R+ V TWNV A +T L L G + S D+ AIG
Sbjct: 525 PKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGF 584
Query: 96 QEVNSMLNKRLKDALFTDQ--WSELFMDALGPFN-FVLVSSVRMQGVILLLFAKYYHLPF 152
+E+ + + A T+Q W+ + N +VL++S ++ GV L +F + H PF
Sbjct: 585 EEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPF 644
Query: 153 LRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILS 212
+RDV D +TG+GG GNKG V++R+ LCF+ H A + ++R ++F I
Sbjct: 645 IRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIAR 704
Query: 213 LQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNT 272
F P + + HD VFW GD N+RI+ + VK I L DQL KN
Sbjct: 705 KLSF--PMGRMLFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGDQLINQKNA 761
Query: 273 WPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS 332
+ +GF EG + FAPT+K+D+ ++ YDTS K R PAWTDR+LW+ + P R +
Sbjct: 762 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRR-----KWPFDRSA 816
Query: 333 HRLQVTQHSYR-----------------SHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRL 375
L + S++ E SDH+PV A L+ + R
Sbjct: 817 EDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVA--LIDIDIFEVEAEERQ 874
Query: 376 EVADEWVR---PEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKH-EDVDG 431
+ E + P V +++ +++ L + + + + ED
Sbjct: 875 NIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMW 934
Query: 432 NTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEP--------------FQISLPSSE 477
T+ S ++ +G +L N +I I + P I+LPSS
Sbjct: 935 VTFLEGSSALNVLSLNGKELL-----NRTITIALKSPDWIKNLEEEMSLEKISIALPSST 989
Query: 478 ----LASSSTDSSGTSSEGE-DDSTLEL-------LAPKSRS---PSPGKSKR-HRSRSP 521
L + ++ EG+ DD + E+ L P S S SP S R +SP
Sbjct: 990 SSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSP 1049
Query: 522 GLAR--FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEE-------- 571
++ P L +RPS R SR+P P S + S + ++ + ++
Sbjct: 1050 TISEGPVPSLPIRPS----RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPP 1105
Query: 572 ----GPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNS-LSPSPQ 626
P P P PP P S P+ + PG G + R + P + + +PQ
Sbjct: 1106 PRPVAPPTRPAPPQRPP--PPSGRSQPSPQAGLAGPGPAG-YSTARPTIPPRAGVISAPQ 1162
Query: 627 GHRGLEEGGLGP 638
H G L P
Sbjct: 1163 SHARASAGRLTP 1174
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 159 bits (401), Expect = 1e-38
Identities = 175/642 (27%), Positives = 269/642 (41%), Gaps = 97/642 (15%)
Query: 52 PSEPRITVVTWNVG-------TAMPPDDVTSLL----HLGGGDD-----SDGADMIAIGL 95
P + R+ V TWNV A +T L L G + S D+ AIG
Sbjct: 530 PKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGF 589
Query: 96 QEVNSMLNKRLKDALFTDQ--WSELFMDALGPFN-FVLVSSVRMQGVILLLFAKYYHLPF 152
+E+ + + A T+Q W+ + N +VL++S ++ GV L +F + H PF
Sbjct: 590 EEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPF 649
Query: 153 LRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILS 212
+RDV D +TG+GG GNKG V++R+ LCF+ H A + ++R ++F I
Sbjct: 650 IRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIAR 709
Query: 213 LQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNT 272
F P + + HD VFW GD N+RI+ + VK I L DQL KN
Sbjct: 710 KLSF--PMGRMLFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGDQLINQKNA 766
Query: 273 WPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS 332
+ +GF EG + FAPT+K+D+ ++ YDTS K R PAWTDR+LW+ + P R +
Sbjct: 767 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRR-----KWPFDRSA 821
Query: 333 HRLQVTQHSYR-----------------SHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRL 375
L + S++ E SDH+PV A L+ + R
Sbjct: 822 EDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVA--LIDIDIFEVEAEERQ 879
Query: 376 EVADEWVR---PEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKH-EDVDG 431
+ E + P V +++ +++ L + + + + ED
Sbjct: 880 NIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMW 939
Query: 432 NTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEP--------------FQISLPSSE 477
T+ S ++ +G +L N +I I + P I+LPSS
Sbjct: 940 VTFLEGSSALNVLSLNGKELL-----NRTITIALKSPDWIKNLEEEMSLEKISIALPSST 994
Query: 478 ----LASSSTDSSGTSSEGE-DDSTLEL-------LAPKSRS---PSPGKSKR-HRSRSP 521
L + ++ EG+ DD + E+ L P S S SP S R +SP
Sbjct: 995 SSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSP 1054
Query: 522 GLAR--FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGP 579
++ P L +RPS R SR+P P S + S + ++ ++ P+ P
Sbjct: 1055 TISEGPVPSLPIRPS----RAPSRTPGPPSAQSSPIDAQPAT-----PLPQKDPAQPLEP 1105
Query: 580 WAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREAL-APNS 620
PP P + PA P G S P R+ AP S
Sbjct: 1106 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKS 1147
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 120 bits (300), Expect = 5e-27
Identities = 97/345 (28%), Positives = 147/345 (42%), Gaps = 51/345 (14%)
Query: 41 QLPAKKNAALGPSEPRITVVTWNVGTAMPPDDVTS-LLHLGGGDDSDGA------DMIAI 93
Q+ K + P I + TWN+G A PP +TS L G G D + D+ I
Sbjct: 389 QMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVI 448
Query: 94 GLQEVNSMLNKRLKDALFTDQWSELFMDALGPFNFVLVSSVRMQ---GVILLLFAKYYHL 150
G QE D L +W E+ +L V +V + + +++ AK H
Sbjct: 449 GTQE----------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHE 498
Query: 151 PFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTI 210
+ + TD +TG+ GNKG V V G L F+N HL + +K +R N+ I
Sbjct: 499 NRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNI 558
Query: 211 LSLQQFQGPGAQGILDHDL------VFWFGDLNFRIE--SYDLHFVKFAIDSDQLHQLWE 262
L +F G + + ++ +FWFGDLN+R++ +++ + I Q L
Sbjct: 559 L---RFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLS 615
Query: 263 KDQLNMAKNTWPILKGFQEGPLNFAPTFKFD-------VGTNKYDTSAKKRKPAWTDRIL 315
DQL + + F+E + FAPT++F+ T + T K P+W DR+L
Sbjct: 616 HDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVL 675
Query: 316 WKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQF 360
WK + V SY S + SDH PV A F
Sbjct: 676 WK-------------SYPLVHVVCQSYGSTSDIMTSDHSPVFATF 707
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 120 bits (300), Expect = 5e-27
Identities = 97/345 (28%), Positives = 147/345 (42%), Gaps = 51/345 (14%)
Query: 41 QLPAKKNAALGPSEPRITVVTWNVGTAMPPDDVTS-LLHLGGGDDSDGA------DMIAI 93
Q+ K + P I + TWN+G A PP +TS L G G D + D+ I
Sbjct: 390 QMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVI 449
Query: 94 GLQEVNSMLNKRLKDALFTDQWSELFMDALGPFNFVLVSSVRMQ---GVILLLFAKYYHL 150
G QE D L +W E+ +L V +V + + +++ AK H
Sbjct: 450 GTQE----------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHE 499
Query: 151 PFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTI 210
+ + TD +TG+ GNKG V V G L F+N HL + +K +R N+ I
Sbjct: 500 NRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNI 559
Query: 211 LSLQQFQGPGAQGILDHDL------VFWFGDLNFRIE--SYDLHFVKFAIDSDQLHQLWE 262
L +F G + + ++ +FWFGDLN+R++ +++ + I Q L
Sbjct: 560 L---RFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLS 616
Query: 263 KDQLNMAKNTWPILKGFQEGPLNFAPTFKFD-------VGTNKYDTSAKKRKPAWTDRIL 315
DQL + + F+E + FAPT++F+ T + T K P+W DR+L
Sbjct: 617 HDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVL 676
Query: 316 WKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQF 360
WK + V SY S + SDH PV A F
Sbjct: 677 WK-------------SYPLVHVVCQSYGSTSDIMTSDHSPVFATF 708
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
sapiens]
Length = 1258
Score = 109 bits (273), Expect = 7e-24
Identities = 91/330 (27%), Positives = 140/330 (42%), Gaps = 46/330 (13%)
Query: 52 PSEPRITVVTWNVGTAMPPDDVTSLLHLGG-GDDSDGA------DMIAIGLQEVNSMLNK 104
P + + TWN+G+ PP +VTS G G D D+ G QE NS+ ++
Sbjct: 421 PDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQE-NSVGDR 479
Query: 105 RLKDALFTDQWSELFMDALGPFNFVLVSSVRMQG---VILLLFAKYYHLPFLRDVQTDCT 161
+W +L L + + MQ + + + K H + V T
Sbjct: 480 ---------EWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSV 530
Query: 162 RTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGA 221
+TG+ GNKG V V G F+NCHL + +K +R N+ IL L G
Sbjct: 531 KTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSL-GDRQ 589
Query: 222 QGILDHDL----VFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILK 277
D L +FWFGDLN+R++ D+ + I + L DQLN+ + +
Sbjct: 590 LNAFDISLRFTHLFWFGDLNYRLD-MDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFL 648
Query: 278 GFQEGPLNFAPTFKFDVGT-------NKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGR 330
F E ++F PT++++ G+ + T + P+W DRILWK S
Sbjct: 649 RFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWK----------SYP 698
Query: 331 KSHRLQVTQHSYRSHMEYTVSDHKPVAAQF 360
++H + +SY + SDH PV F
Sbjct: 699 ETH---IICNSYGCTDDIVTSDHSPVFGTF 725
Score = 32.0 bits (71), Expect = 1.8
Identities = 31/99 (31%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 527 PGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAV 586
P A PS+ + + A P+PQ L R GSS S EE LP P PP +
Sbjct: 1004 PARAPVPSATKNKVAITVPAPQ---LGHHRHPRVGEGSS--SDEESGGTLPPPDFPPPPL 1058
Query: 587 PRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSP 625
P S LP P G G + P P P
Sbjct: 1059 PDSAIFLPPSLDPLPGPVVRGRGGAEARGPPPPKAHPRP 1097
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 106 bits (264), Expect = 7e-23
Identities = 92/333 (27%), Positives = 148/333 (44%), Gaps = 50/333 (15%)
Query: 59 VVTWNV-GTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKDALFTDQWSE 117
V TWN+ G P + L D + D+ IG+QE S ++R +W
Sbjct: 303 VATWNMQGQKELPPSLDEFLLPAEADYAQ--DLYVIGVQEGCS--DRR--------EWET 350
Query: 118 LFMDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSV 177
+ LGP ++VL+SS + + LF + + F +V+ T + KG + +
Sbjct: 351 RLQETLGP-HYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGI 409
Query: 178 RLAAFGHMLCFLNCHLPAHMDK-AEQRKDNFQTILSL---------QQFQGPGAQGILDH 227
FG F+ H + K AE+ D +T+ +L ++ A
Sbjct: 410 SFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRF 469
Query: 228 DLVFWFGDLNFRIESYDLHFVKFAIDS-------DQLHQLWEKDQLNMAKNTWPILKGFQ 280
D VFWFGD NFR+ + +D+ + L + DQL I KGFQ
Sbjct: 470 DEVFWFGDFNFRLSGG-----RTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQ 524
Query: 281 EGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQH 340
E ++F P++KFD+G + YD+++K+R P++TDR+L+ R H+ +
Sbjct: 525 EPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLY-------------RSRHKGDICPV 571
Query: 341 SYRSHMEYTVSDHKPVAAQFLLQF-AFRDDMPL 372
SY S SDH+PV F ++ RD++PL
Sbjct: 572 SYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPL 604
Score = 30.4 bits (67), Expect = 5.2
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 11/118 (9%)
Query: 502 APKSRSPSPGKSKRHR-SRSPGLARFPGLALRPSSRER--RGASRSPSPQSRRLSRVAPD 558
AP S SP+ S S AR +A RP +R R R S RR R + +
Sbjct: 42 APGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQE 101
Query: 559 ----RSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLP----ALRLETVDPGGGGS 608
R+ SRGS + G P PP + SL +P L E P GG+
Sbjct: 102 DLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGN 159
>gi|239752992 PREDICTED: hypothetical protein XP_002345322 [Homo
sapiens]
Length = 277
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNG 563
++R P+PG S + R R GLA P A P + G SR+ SP++ R R +P + G
Sbjct: 27 QTRIPTPGASPQLRPRQAGLALSPQRAASPRLGKAAGPSRNSSPRAFR-GRGSPKFA--G 83
Query: 564 SSRGSSEEGPSGLPGPWAFPPAVPRS 589
+ R S+E+G PW P P++
Sbjct: 84 AVRESAEDGEGPFSSPWNSPRTTPKA 109
>gi|239747550 PREDICTED: hypothetical protein XP_002347647 [Homo
sapiens]
Length = 277
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNG 563
++R P+PG S + R R GLA P A P + G SR+ SP++ R R +P + G
Sbjct: 27 QTRIPTPGASPQLRPRQAGLALSPQRAASPRLGKAAGPSRNSSPRAFR-GRGSPKFA--G 83
Query: 564 SSRGSSEEGPSGLPGPWAFPPAVPRS 589
+ R S+E+G PW P P++
Sbjct: 84 AVRESAEDGEGPFSSPWNSPRTTPKA 109
>gi|239741424 PREDICTED: hypothetical protein XP_002342197 [Homo
sapiens]
Length = 277
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNG 563
++R P+PG S + R R GLA P A P + G SR+ SP++ R R +P + G
Sbjct: 27 QTRIPTPGASPQLRPRQAGLALSPQRAASPRLGKAAGPSRNSSPRAFR-GRGSPKFA--G 83
Query: 564 SSRGSSEEGPSGLPGPWAFPPAVPRS 589
+ R S+E+G PW P P++
Sbjct: 84 AVRESAEDGEGPFSSPWNSPRTTPKA 109
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 44.7 bits (104), Expect = 3e-04
Identities = 46/182 (25%), Positives = 68/182 (37%), Gaps = 15/182 (8%)
Query: 466 TEPFQISLPSSELASSSTDSSGTSSEGEDDSTLE-----------LLAPKSRSPSPGKSK 514
+E S S +SSS+ SSG+ +EGE++ A SR+ SP S
Sbjct: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
Query: 515 RHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSS----E 570
S S + + SS +S S S S S + SS+ SS SS +
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDED 2676
Query: 571 EGPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSPQGHRG 630
S P A P + LP + + P ++ AP +P PQ +
Sbjct: 2677 SSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQP 2736
Query: 631 LE 632
L+
Sbjct: 2737 LQ 2738
Score = 33.1 bits (74), Expect = 0.80
Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 3/104 (2%)
Query: 472 SLPSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLAL 531
S SS +SSS+ SS +SS D + +P+P ++ P A
Sbjct: 2651 SSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKA 2710
Query: 532 RPSSRERRGASRSPSPQS---RRLSRVAPDRSSNGSSRGSSEEG 572
RPS+ + +P PQ+ + + P + SR EG
Sbjct: 2711 RPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREG 2754
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/129 (34%), Positives = 55/129 (42%), Gaps = 24/129 (18%)
Query: 472 SLPSSELASSSTDSSGTSSEGEDDSTLELL-----APK-----SRSPSPGKSKRHRSRSP 521
S SS SSS+DS G+S + + L+ + APK R P P +KR R S
Sbjct: 2550 SSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS- 2608
Query: 522 GLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPS-GLPGPW 580
SS +S S S S S + SS+ SS SS PS PGP
Sbjct: 2609 -----------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657
Query: 581 AFP-PAVPR 588
A P PA P+
Sbjct: 2658 ALPKPASPK 2666
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/129 (29%), Positives = 45/129 (34%), Gaps = 21/129 (16%)
Query: 472 SLPSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGK----------------SKR 515
S SS +SSS+ SS +SS S+ + S SPSP K
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE 2672
Query: 516 HRSRSP-----GLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSE 570
RSRSP L L+ P R R SP Q S R G SR S
Sbjct: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSH 2732
Query: 571 EGPSGLPGP 579
+ P P
Sbjct: 2733 KRRRETPSP 2741
Score = 39.3 bits (90), Expect = 0.011
Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
Query: 455 YSHNHSILIGITEPFQISLPSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSK 514
+S LI T P + S+ SS ++ TSS G+ + L + AP G+
Sbjct: 2455 FSDQSRCLIAQTTP----VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPP 2510
Query: 515 RHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPS 574
S G + LA ++ERR +S S S S S + SS+ S SS+ S
Sbjct: 2511 A----STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566
Query: 575 GLP 577
LP
Sbjct: 2567 SLP 2569
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/174 (31%), Positives = 70/174 (40%), Gaps = 21/174 (12%)
Query: 472 SLPSSELAS---SSTDSSGTSSEGEDDSTLELLAP-KSRSPSPGK----SKRHRSRSPGL 523
S P EL S S SG+S ST +P +S SP P S R RS S
Sbjct: 875 SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSS 934
Query: 524 ARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFP 583
+ P R +SR SRS SP S SR+ P S +GSS ++ P P
Sbjct: 935 SPSPS---RVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE-------TP 984
Query: 584 PAVPRSLGLLPALRLETVDPGG---GGSWGPDREALAPNSLSPSPQGHRGLEEG 634
P S + P +++ P G GS P + + +SL S G L G
Sbjct: 985 PRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAG 1038
Score = 38.5 bits (88), Expect = 0.019
Identities = 37/109 (33%), Positives = 48/109 (44%), Gaps = 10/109 (9%)
Query: 477 ELASSSTDSSGTSSEGEDDS----TLELLAPKSRSPSPGKSKRHRSRSP---GLARFPGL 529
E++SS T + + + D T +SRSP+ K R RSR+P G +R
Sbjct: 452 EISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSP 511
Query: 530 ALRPS-SRERRGASRSPSPQSRRLSRVAP--DRSSNGSSRGSSEEGPSG 575
R S S +R G SRSP + R S P RS N RG S G
Sbjct: 512 QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRG 560
Score = 36.2 bits (82), Expect = 0.095
Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 3/100 (3%)
Query: 476 SELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSS 535
S + S S G S +SRS +P + R RSR+P AR G + R +
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTP--ARRSGRS-RSRT 685
Query: 536 RERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSG 575
RRG SRS +P+ R + R SR G SG
Sbjct: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSG 725
Score = 35.8 bits (81), Expect = 0.12
Identities = 43/149 (28%), Positives = 59/149 (39%), Gaps = 19/149 (12%)
Query: 486 SGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRE-------R 538
S ++ G S +SRS +P + R RSR+P AR + P+ R R
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTP--ARRRSRSRTPTRRRSRSRTPAR 611
Query: 539 RGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRL 598
RG SRS +P RR +P R + S + G S P RS PA R
Sbjct: 612 RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS----RTPARRGRSRSRTPARR- 666
Query: 599 ETVDPGGGGSWGPDREALAPNSLSPSPQG 627
G S P R + S +P+ +G
Sbjct: 667 -----GRSRSRTPARRSGRSRSRTPARRG 690
Score = 35.8 bits (81), Expect = 0.12
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
Query: 481 SSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRG 540
S + +S S T + +SRS +P +R RSR+P + R + P RR
Sbjct: 1911 SRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970
Query: 541 ASR-SPSPQSRRLSRVAPDRSSNGSSRGS 568
SR SP + R SR +P SR S
Sbjct: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
Score = 35.4 bits (80), Expect = 0.16
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSR--VAPDRSS 561
K RS S K ++HRS +P R + +R S +P+P+SRR R A SS
Sbjct: 217 KHRSESESKKRKHRSPTPKSKR-----KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASS 271
Query: 562 NGSSRGSS 569
+ +SR S
Sbjct: 272 SDTSRSRS 279
Score = 35.4 bits (80), Expect = 0.16
Identities = 40/125 (32%), Positives = 49/125 (39%), Gaps = 24/125 (19%)
Query: 475 SSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLA--LR 532
SS +SSS+ SS +SS S+ + S S S S PG P A +
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667
Query: 533 PSSRERRGASRSP---------------SPQSRRLSRVAP---DRSSNGSSRGS--SEEG 572
P ERR SRSP SP RR P D+ S+ S RGS + G
Sbjct: 2668 PPPGERR--SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725
Query: 573 PSGLP 577
S P
Sbjct: 2726 DSRSP 2730
Score = 35.0 bits (79), Expect = 0.21
Identities = 48/175 (27%), Positives = 58/175 (33%), Gaps = 37/175 (21%)
Query: 474 PSSELASSSTDSSGTSSEGEDDSTLELLAPKS-------RSPSPGKSKRHRSRSPGLARF 526
P S A ST + SS S A K+ RSPSP +R +P
Sbjct: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPG 314
Query: 527 PGLALRPSSRERRGASRSPS-------PQSRRLSRVAPDRSSNGSSRGSSEEGPS----- 574
RPSS E A++ PS + S P S SS G P+
Sbjct: 315 TTSTQRPSSPET--ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE 372
Query: 575 ---GLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSPQ 626
G P P A P L E V+P S P R+ P S PQ
Sbjct: 373 RHGGSPQPLATTP-----------LSQEPVNPPSEAS--PTRDRSPPKSPEKLPQ 414
Score = 35.0 bits (79), Expect = 0.21
Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 6/116 (5%)
Query: 474 PSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRP 533
PS+ S S S+ + + L + SP R R P + +P
Sbjct: 1549 PSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
Query: 534 SS--RERRGASRSPSPQSRRLSRVAPDRSSNGSS---RGSSEEGPSGLPGPWAFPP 584
+ R + G+ SP P++ R P RS +GSS RG S EG S PP
Sbjct: 1609 RAAPRAQSGSDSSPEPKAPA-PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Score = 33.9 bits (76), Expect = 0.47
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 8/73 (10%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDR---S 560
+SRS +P + R RSR+P R R S RRG S S +PQ R S + +R S
Sbjct: 680 RSRSRTPARRGRSRSRTPRRGR-----SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734
Query: 561 SNGSSRGSSEEGP 573
R S P
Sbjct: 735 RTSQRRSRSNSSP 747
Score = 33.5 bits (75), Expect = 0.62
Identities = 30/82 (36%), Positives = 36/82 (43%), Gaps = 13/82 (15%)
Query: 504 KSRSPSPGKSKRHRSRSP-----------GLARFPGLALRPSSRERRGASRSPSPQSRRL 552
+SRS +P K RSRSP G +R P R S +R G SRS + Q R
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
Query: 553 SRVAPDRSSNGSSRGSSEEGPS 574
SR A R SR + G S
Sbjct: 554 SRSA--RRGRSHSRSPATRGRS 573
Score = 33.5 bits (75), Expect = 0.62
Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%)
Query: 505 SRSPSPGKSKRHRSRSP-GLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNG 563
SRSP+ +S R SR G +R P P+SR+R + SP+P R SR +P
Sbjct: 1822 SRSPARQESSRTSSRRRRGRSRTP-----PTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876
Query: 564 SSR 566
SR
Sbjct: 1877 RSR 1879
Score = 32.3 bits (72), Expect = 1.4
Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 22/142 (15%)
Query: 457 HNHSILIGITEPFQISLPSSELASSSTDSSGTSSE-GEDDSTLELLAPKSRSPSPGKSKR 515
H S + EP + S S S+S+ + T+S G S P+ S +S+R
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP----KPRGLQRSRSRSRR 1779
Query: 516 HRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRR---------LSRVAPDRSSNGSSR 566
++R+ G + S R +R SRS + RR +R R+S+ R
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
Query: 567 GSSEEGPSG--------LPGPW 580
G S P+ P PW
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPW 1861
Score = 32.3 bits (72), Expect = 1.4
Identities = 20/63 (31%), Positives = 30/63 (47%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNG 563
+SRS + +R RSR+ ++R + P RR SR+P+ + R SR P
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRS 1958
Query: 564 SSR 566
SR
Sbjct: 1959 RSR 1961
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 16/85 (18%)
Query: 502 APKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGAS-----------RSPSPQSR 550
+P++RS +P RHR RSP ++ SSR RR AS RSPSP+ R
Sbjct: 1713 SPETRSRTP---PRHR-RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768
Query: 551 RLSRVAPDRSSNGSSRGSSEEGPSG 575
L R + RS +R + SG
Sbjct: 1769 GLQR-SRSRSRREKTRTTRRRDRSG 1792
Score = 31.2 bits (69), Expect = 3.1
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Query: 486 SGTSSEGEDDS-TLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRS 544
SG+SSE ++ S T + + + SP KS+ RS L+ A S R + S
Sbjct: 724 SGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783
Query: 545 PSPQSRRLSRVAPDRSSNGSSR 566
P P+ + S+ P RS +GSS+
Sbjct: 784 PCPKQK--SQTPPRRSRSGSSQ 803
Score = 31.2 bits (69), Expect = 3.1
Identities = 29/109 (26%), Positives = 39/109 (35%), Gaps = 11/109 (10%)
Query: 472 SLPSSELASSSTDSSGTSSEGEDDSTLELLAPKSR------SPSPGKSKRHRSRSPGLAR 525
S S EL + S + S T P+ R SP P + R R R
Sbjct: 1691 SRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR-----R 1745
Query: 526 FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPS 574
+ R + RRG S SP P+ + SR R ++R G S
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSS 1794
Score = 30.4 bits (67), Expect = 5.2
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 7/87 (8%)
Query: 474 PSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRP 533
P SE + + S S E S+ +P S P P K RH S SP P A P
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPS--PQPTKVSRHASSSP---ESPKPAPAP 447
Query: 534 SSRERRGASRSPSPQSRRLSRVAPDRS 560
S R S SP+ ++R R D+S
Sbjct: 448 GS--HREISSSPTSKNRSHGRAKRDKS 472
Score = 30.0 bits (66), Expect = 6.8
Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 11/98 (11%)
Query: 504 KSRS-PSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSN 562
+SRS SP +R RSR+P R + P +R SRSP RR SR R++
Sbjct: 2005 RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPL-AIRRRSRSRTPRTAR 2063
Query: 563 G---------SSRGSSEEGPSGLPGPWAFPPAVPRSLG 591
G + R S G S A PPA G
Sbjct: 2064 GKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSG 2101
Score = 29.6 bits (65), Expect = 8.9
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Query: 504 KSRS-PSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSN 562
+SRS SP +R RSR+P ++R + RR SR+ + R SR +P
Sbjct: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR 1922
Query: 563 GSSR 566
SR
Sbjct: 1923 SRSR 1926
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 43.9 bits (102), Expect = 5e-04
Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 25/124 (20%)
Query: 521 PGLARFPGL---------ALRPSSRERRGASRSPSPQSRRLSRVAPDRSS-NGSSRGSSE 570
PG A FPG A P S G P PQ ++ P NGS G E
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGE 397
Query: 571 EGPSGLPGP----WAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSPQ 626
GP+G+PG A P P P LR +PG G+ G P P+
Sbjct: 398 MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG-----------EPGPR 446
Query: 627 GHRG 630
G RG
Sbjct: 447 GERG 450
Score = 36.2 bits (82), Expect = 0.095
Identities = 45/139 (32%), Positives = 53/139 (38%), Gaps = 15/139 (10%)
Query: 507 SPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRV---APDRSSNG 563
SP P K + PG PG + R G P P + + AP
Sbjct: 736 SPGP-KGDKGEPGGPGADGVPG---KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791
Query: 564 SSRGS-SEEGPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLS 622
RGS E G +G PGP FP A P G P + E PG G GP A P
Sbjct: 792 GPRGSPGERGETGPPGPAGFPGA-PGQNG-EPGGKGERGAPGEKGEGGPPGVAGPPGGSG 849
Query: 623 PS----PQGHRGLEEGGLG 637
P+ PQG +G E G G
Sbjct: 850 PAGPPGPQGVKG-ERGSPG 867
Score = 35.8 bits (81), Expect = 0.12
Identities = 43/140 (30%), Positives = 49/140 (35%), Gaps = 13/140 (9%)
Query: 508 PSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSS-NGSSR 566
P GK PG A PGL P RG SP P+ + P G
Sbjct: 703 PEGGKGAAGPPGPPGAAGTPGLQGMPG---ERGGLGSPGPKGDKGEPGGPGADGVPGKDG 759
Query: 567 GSSEEGPSGLPGPWAFPPAVPRSLGL--LPALRLETVDPGGGGSWGPDREALAPNSL--- 621
GP G PGP A P G LP + PG G GP A P +
Sbjct: 760 PRGPTGPIGPPGP-AGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQN 818
Query: 622 -SPSPQGHRGL--EEGGLGP 638
P +G RG E+G GP
Sbjct: 819 GEPGGKGERGAPGEKGEGGP 838
Score = 35.4 bits (80), Expect = 0.16
Identities = 43/143 (30%), Positives = 51/143 (35%), Gaps = 13/143 (9%)
Query: 508 PSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSN----G 563
P K +R PG A FPG P G P P P + N G
Sbjct: 856 PQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPG 915
Query: 564 SSRGSSEEGPSGLPG----PWA-FPPAVPRSLGL--LPALRLETVDPGGGGSWG-PDREA 615
S S +G +G PG P A PP P LG+ + R PG G G P +
Sbjct: 916 SPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975
Query: 616 LAPNSLSPSPQGHRGLEEGGLGP 638
+ S P G G E G GP
Sbjct: 976 VKGESGKPGANGLSG-ERGPPGP 997
Score = 35.0 bits (79), Expect = 0.21
Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 17/121 (14%)
Query: 520 SPGLARFPGLALRPSSRERRGASRSPSPQSRR-LSRVAPDRSSNGSSRGSSEEGPSGLPG 578
+PGL GL + G +P + R L A R ++G+ + GP G PG
Sbjct: 280 APGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPG 339
Query: 579 PWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSL-SPSPQGHRGLEEGGLG 637
FP + P + E G GS G AP P PQGH G +G G
Sbjct: 340 TAGFPGS--------PGAKGEVGPAGSPGSNG------APGQRGEPGPQGHAG-AQGPPG 384
Query: 638 P 638
P
Sbjct: 385 P 385
Score = 33.5 bits (75), Expect = 0.62
Identities = 43/157 (27%), Positives = 54/157 (34%), Gaps = 37/157 (23%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALR---PSSRERRGASRSPSPQSRRLSRVAPDRS 560
+S P P R + PG+ FPG P RG P PQ
Sbjct: 559 ESGRPGPPGPSGPRGQ-PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ------------ 605
Query: 561 SNGSSRGSSEEGPSGLPGPWA-------FPPAVPRSLGLLPALRLETVDPGGGGSWGPDR 613
G + E GP G PGP P P+ L LP + G G GP
Sbjct: 606 --GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKG 663
Query: 614 EALAP-------NSLSPSPQGHRGLE-----EGGLGP 638
+A AP ++ +P +G GL GG GP
Sbjct: 664 DAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP 700
Score = 31.2 bits (69), Expect = 3.1
Identities = 37/141 (26%), Positives = 47/141 (33%), Gaps = 12/141 (8%)
Query: 508 PSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLS------RVAPDRSS 561
P G+ + PG PG P + G+ SP P S +P S
Sbjct: 98 PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS 157
Query: 562 NGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLL-----PALRLETVDPGGGGSWGPDREAL 616
G + G +G PGP A PP P G P PG G GP
Sbjct: 158 YDVKSGVAVGGLAGYPGP-AGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPG 216
Query: 617 APNSLSPSPQGHRGLEEGGLG 637
P ++ PS + E G G
Sbjct: 217 PPGAIGPSGPAGKDGESGRPG 237
Score = 31.2 bits (69), Expect = 3.1
Identities = 40/129 (31%), Positives = 45/129 (34%), Gaps = 15/129 (11%)
Query: 504 KSRSPSPGKSKRHRSRSP-GLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAP-DRSS 561
K S PG + R P G PGLA R G S R S DR
Sbjct: 977 KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGE 1036
Query: 562 NGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSL 621
NGS G G PGP P G E+ G G+ GP A +
Sbjct: 1037 NGSPGAPGAPGHPGPPGP-VGPAGKSGDRG-------ESGPAGPAGAPGP-----AGSRG 1083
Query: 622 SPSPQGHRG 630
+P PQG RG
Sbjct: 1084 APGPQGPRG 1092
>gi|119943086 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform b [Homo sapiens]
Length = 747
Score = 43.9 bits (102), Expect = 5e-04
Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 403 DWIGLYRVGFRHCKDYVAYVWAKHED--VDGNTYQ--VTFSEESLPKGHGDFILGYYSHN 458
DW+G+++VG+ +DY ++W+ + V+G+T + F LP G+F Y +
Sbjct: 48 DWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTH 107
Query: 459 HSILIGITEPFQI--SLPSSELASSSTDSS 486
+ G + PFQ S P EL + + +
Sbjct: 108 KGEIRGASTPFQFRASSPVEELLTMEDEGN 137
>gi|21361682 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform a [Homo sapiens]
Length = 789
Score = 43.9 bits (102), Expect = 5e-04
Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 403 DWIGLYRVGFRHCKDYVAYVWAKHED--VDGNTYQ--VTFSEESLPKGHGDFILGYYSHN 458
DW+G+++VG+ +DY ++W+ + V+G+T + F LP G+F Y +
Sbjct: 48 DWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTH 107
Query: 459 HSILIGITEPFQI--SLPSSELASSSTDSS 486
+ G + PFQ S P EL + + +
Sbjct: 108 KGEIRGASTPFQFRASSPVEELLTMEDEGN 137
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 43.9 bits (102), Expect = 5e-04
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 19/158 (12%)
Query: 471 ISLPSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLA 530
+S P + S ++ G S +S + +P+ PSP S R +
Sbjct: 222 LSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSA---------- 271
Query: 531 LRPSSRERRGASRSPSPQS-RRLSRVAPD--RSSNGSSRGSSEEGPSGLPGPWAFPPAVP 587
R +S E R S S SP+ + V+P+ R + S GS + GP G P PW P+
Sbjct: 272 -RTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSA- 329
Query: 588 RSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSP 625
S PA +V P G W P +++P P+P
Sbjct: 330 SSGPWKPAKPAPSVSP---GPWKP-IPSVSPGPWKPTP 363
Score = 38.1 bits (87), Expect = 0.025
Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 10/128 (7%)
Query: 468 PFQISLPSSELASSSTDSSGTSSEGEDDS--TLELLAPKSRSPSPGKSKRHRSRSPGLA- 524
P S P S + ++S + G S +S + +P+ R PSP +S P ++
Sbjct: 239 PPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSP 298
Query: 525 --RFPGLALRPSSRERRGASRSPSPQSRRLSRVA----PDRSSNGSSRGSSEEGPSGLPG 578
R P A+ P S + G SP P S + P + + S G + PS PG
Sbjct: 299 EPRRPAPAVSPGSW-KPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPG 357
Query: 579 PWAFPPAV 586
PW P+V
Sbjct: 358 PWKPTPSV 365
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 43.1 bits (100), Expect = 8e-04
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 7/98 (7%)
Query: 474 PSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRP 533
P+ + + SG + E S+ AP + + SP SK+HRSR R PG
Sbjct: 514 PTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPA-SPWDSKKHRSRD----RKPGSHASS 568
Query: 534 SSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEE 571
S+R RR SRS S +RR SR + DR GS R S E
Sbjct: 569 SAR-RRSRSRSRSRSTRRRSR-STDRRRGGSRRSRSRE 604
Score = 34.3 bits (77), Expect = 0.36
Identities = 43/119 (36%), Positives = 49/119 (41%), Gaps = 22/119 (18%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRE---RRGASRSPSP------QSRRLSR 554
+SRS S +S R RSRS R G + R SRE RR S SP P SRR
Sbjct: 573 RSRSRSRSRSTRRRSRSTDRRR--GGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERH 630
Query: 555 VAPDRSSNGS--------SRGS--SEEGPSGLPGPWAFPPAVPRSLGLLPALRLETVDP 603
R GS SRG S +G P P A PP+ S G + R V P
Sbjct: 631 RGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAP-APPPSGSTSCGDRDSRRRGAVPP 688
>gi|73858559 proline/serine-rich coiled-coil 1 isoform c [Homo
sapiens]
Length = 363
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/147 (30%), Positives = 63/147 (42%), Gaps = 37/147 (25%)
Query: 503 PKSRSPSPGKSKRHRSRSPGLARFPGLALR---PSSRERRGASRSPSPQSRRLSRVAPDR 559
P R+ + +++ + R G F GL L+ PS P P + S +AP
Sbjct: 205 PSGRAAASEETRAAKLRVSGSGEFVGLTLKFLHPSP---------PGPPTPIRSVLAPQP 255
Query: 560 SSNGSSR-----GSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDRE 614
S++ S R G++ + S LP P A+PR +P L +V PG G
Sbjct: 256 STSNSQRLPRPQGAAAKSSSQLP----IPSAIPRPASRMP-LTSRSVPPGRG-------- 302
Query: 615 ALAPNSLS-------PSPQGHRGLEEG 634
AL P+SLS PS GHR E G
Sbjct: 303 ALPPDSLSTRKGLPRPSTAGHRVRESG 329
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 16/105 (15%)
Query: 496 STLELLAPKSRS-PSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRL-- 552
ST L+PKS++ PS + HR SP + PG L P RG + SP + RR
Sbjct: 454 STASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEE 513
Query: 553 -----SRVAPDRSSNGSSRGSSEE--------GPSGLPGPWAFPP 584
S P+ S R S+E+ PS P P PP
Sbjct: 514 AKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPP 558
>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
sapiens]
Length = 691
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 10/135 (7%)
Query: 375 LEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAK--HEDVDGN 432
L VA ++ + Y + S+ DWIG+++V +DY +VW+ DG+
Sbjct: 18 LNVARTYIPNTKVECHYTLPPGTMPSASDWIGIFKVEAACVRDYHTFVWSSVPESTTDGS 77
Query: 433 TY--QVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQISLPSSELASSSTDSSGTSS 490
V F LPK Y + + G + PFQ P D T
Sbjct: 78 PIHTSVQFQASYLPKPGAQLYQFRYVNRQGQVCGQSPPFQFREP------RPMDELVTLE 131
Query: 491 EGEDDSTLELLAPKS 505
E + S + L+ PK+
Sbjct: 132 EADGGSDILLVVPKA 146
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/125 (32%), Positives = 47/125 (37%), Gaps = 8/125 (6%)
Query: 504 KSRSPS---PGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRS 560
+SRSPS P + R RSRS R P RPS R R R P P R SR +P R
Sbjct: 289 RSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR-SPVRR 347
Query: 561 SNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNS 620
SS S S PP P P + + P S P R P+
Sbjct: 348 RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSP----SASPPRRRHRPSP 403
Query: 621 LSPSP 625
+ P
Sbjct: 404 PATPP 408
Score = 40.0 bits (92), Expect = 0.007
Identities = 47/184 (25%), Positives = 71/184 (38%), Gaps = 34/184 (18%)
Query: 465 ITEPFQISLPSSELASSSTDSSGTSSEGEDDSTLELLAPKSRSP----SPGKSKRHRSRS 520
+T+ SL S SS S + + +P+ R+P SP +R S S
Sbjct: 648 VTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS 707
Query: 521 PGLARFPGLALRPSSRERRGA-------SRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGP 573
P + P + RP R R + SPSPQS R RV+ RS +GS ++++ P
Sbjct: 708 PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR--RVSSSRSVSGSPEPAAKKPP 765
Query: 574 SGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSPQGHRGLEE 633
+ PP+ +S +W P S +PSP R ++
Sbjct: 766 A--------PPSPVQS-------------QSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQ 804
Query: 634 GGLG 637
G G
Sbjct: 805 EGGG 808
Score = 38.1 bits (87), Expect = 0.025
Identities = 37/133 (27%), Positives = 47/133 (35%), Gaps = 18/133 (13%)
Query: 482 STDSSGTSSEGEDDSTLELLAPK-----------SRSPSPGKSKRHRSRSPGLARFPGLA 530
S+ SG+SS ED+ SRS SP KR + SP R
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSP-RGRRRRSP 550
Query: 531 LRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSL 590
P +R RR S +P P+ RR P R R S P P + P + R
Sbjct: 551 SPPPTRRRRSPSPAPPPRRRRTPTPPPRR------RTPSPPPRRRSPSPRRYSPPIQRRY 604
Query: 591 GLLPALRLETVDP 603
P + T P
Sbjct: 605 SPSPPPKRRTASP 617
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/85 (37%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 504 KSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNG 563
+ RSPSP ++R RS SP A P P+ RR R+PSP RR S +P R S
Sbjct: 546 RRRSPSPPPTRRRRSPSP--APPPRRRRTPTPPPRR---RTPSPPPRRRS-PSPRRYSPP 599
Query: 564 SSRGSSEEGPSGLPGPWAFPPAVPR 588
R S P A PP P+
Sbjct: 600 IQRRYSPSPPP--KRRTASPPPPPK 622
Score = 29.6 bits (65), Expect = 8.9
Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 9/59 (15%)
Query: 499 ELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAP 557
E P+SRS S +S R RSRSP R R R SRS SP+ R R P
Sbjct: 272 EKTRPRSRSRSKSRS-RTRSRSPSHTR--------PRRRHRSRSRSYSPRRRPSPRRRP 321
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,579,935
Number of Sequences: 37866
Number of extensions: 1556066
Number of successful extensions: 9033
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 524
Number of HSP's that attempted gapping in prelim test: 7288
Number of HSP's gapped (non-prelim): 1990
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.