Guide to the Human Genome
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Search of human proteins with 5032013

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5032013 kinesin family member 20A [Homo sapiens]
         (890 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5032013 kinesin family member 20A [Homo sapiens]                  1755   0.0  
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                   405   e-112
gi|20143967 kinesin family member 23 isoform 1 [Homo sapiens]         253   7e-67
gi|6754472 kinesin family member 23 isoform 2 [Homo sapiens]          250   5e-66
gi|46852174 kinesin family member 3A [Homo sapiens]                   155   1e-37
gi|46852172 kinesin family member 13B [Homo sapiens]                  152   1e-36
gi|4758646 kinesin family member 3B [Homo sapiens]                    150   5e-36
gi|157738629 kinesin family member 13A isoform d [Homo sapiens]       149   9e-36
gi|157738627 kinesin family member 13A isoform c [Homo sapiens]       149   9e-36
gi|157738625 kinesin family member 13A isoform b [Homo sapiens]       149   9e-36
gi|157738621 kinesin family member 13A isoform a [Homo sapiens]       149   9e-36
gi|13699824 kinesin family member 11 [Homo sapiens]                   140   7e-33
gi|116686122 kinesin family member 4 [Homo sapiens]                   137   6e-32
gi|150010604 kinesin family member 4B [Homo sapiens]                  135   1e-31
gi|9910266 kinesin family member 15 [Homo sapiens]                    135   2e-31
gi|40254834 kinesin family member 1C [Homo sapiens]                   135   2e-31
gi|71061468 centromere protein E [Homo sapiens]                       134   5e-31
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]     132   1e-30
gi|41393563 kinesin family member 1B isoform b [Homo sapiens]         132   1e-30
gi|45446749 kinesin family member 5A [Homo sapiens]                   131   2e-30
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]      129   1e-29
gi|170784809 kinesin family member 17 isoform b [Homo sapiens]        128   2e-29
gi|170784807 kinesin family member 17 isoform a [Homo sapiens]        128   2e-29
gi|41352705 kinesin family member 3C [Homo sapiens]                   128   2e-29
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]        127   4e-29
gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]        126   1e-28
gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]        126   1e-28
gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]         126   1e-28
gi|4758650 kinesin family member 5C [Homo sapiens]                    125   2e-28
gi|7661878 kinesin family member 14 [Homo sapiens]                    125   2e-28

>gi|5032013 kinesin family member 20A [Homo sapiens]
          Length = 890

 Score = 1755 bits (4545), Expect = 0.0
 Identities = 890/890 (100%), Positives = 890/890 (100%)

Query: 1   MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSED 60
           MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSED
Sbjct: 1   MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSED 60

Query: 61  SMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHR 120
           SMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHR
Sbjct: 61  SMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHR 120

Query: 121 FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGIL 180
           FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGIL
Sbjct: 121 FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGIL 180

Query: 181 PRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTS 240
           PRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTS
Sbjct: 181 PRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTS 240

Query: 241 LKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFS 300
           LKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFS
Sbjct: 241 LKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFS 300

Query: 301 IWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLK 360
           IWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLK
Sbjct: 301 IWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLK 360

Query: 361 VGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKS 420
           VGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKS
Sbjct: 361 VGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKS 420

Query: 421 GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCM 480
           GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCM
Sbjct: 421 GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCM 480

Query: 481 IVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAK 540
           IVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAK
Sbjct: 481 IVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAK 540

Query: 541 ADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQM 600
           ADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQM
Sbjct: 541 ADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQM 600

Query: 601 QQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQ 660
           QQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQ
Sbjct: 601 QQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQ 660

Query: 661 QSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPP 720
           QSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPP
Sbjct: 661 QSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPP 720

Query: 721 PSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDD 780
           PSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDD
Sbjct: 721 PSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDD 780

Query: 781 ILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPN 840
           ILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPN
Sbjct: 781 ILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPN 840

Query: 841 QQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY 890
           QQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY
Sbjct: 841 QQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY 890


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score =  405 bits (1040), Expect = e-112
 Identities = 271/722 (37%), Positives = 408/722 (56%), Gaps = 98/722 (13%)

Query: 35  VRKNLLSDCSVVSTSLEDKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVE 94
           ++ +L  + S+V+ + E      S +S + ++V LR+RP   SE E  E +GCV I + +
Sbjct: 33  IKLDLSHEFSLVAPNTEAN----SFESKDYLQVCLRIRPFTQSEKEL-ESEGCVHILDSQ 87

Query: 95  TLVLQAPKDSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNW 154
           T+VL+ P+     + +E+  GQ   +F+FS++FGP   Q  FF   + + VKD+LKGQ+ 
Sbjct: 88  TVVLKEPQCILG-RLSEKSSGQMAQKFSFSKVFGPATTQKEFFQGCIMQPVKDLLKGQSR 146

Query: 155 LIYTYGVTNSGKTHTIQGTIKDGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDS 214
           LI+TYG+TNSGKT+T QGT ++ GILPR+L ++F+SLQ +L+   +LKP  S E + L S
Sbjct: 147 LIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMNLKPHRSREYLRLSS 206

Query: 215 KQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSS 274
           +Q ++E   K +LL    Q +E+                +   DS      S++   + S
Sbjct: 207 EQEKEEIASKSALLR---QIKEV----------------TVHNDSDDTLYGSLTNSLNIS 247

Query: 275 QLDETSHRWAQPDTAPLPVPANIRFSIWISFFEIYNELLYDLLEPPSQQ-RKRQTLRLCE 333
           + +E+   + Q   A L +  +I+FS+W+SFFEIYNE +YDL  P S + +KR+ LRL +
Sbjct: 248 EFEESIKDYEQ---ANLNMANSIKFSVWVSFFEIYNEYIYDLFVPVSSKFQKRKMLRLSQ 304

Query: 334 DQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQ- 392
           D  G  ++KDL WI V D++EA++LLK+G K+QS A T LN  SSRSHSIF+++IL ++ 
Sbjct: 305 DVKGYSFIKDLQWIQVSDSKEAYRLLKLGIKHQSVAFTKLNNASSRSHSIFTVKILQIED 364

Query: 393 GEGDIVPKISELSLCDLAGSER-CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNR 451
            E   V ++SELSLCDLAGSER  K Q  GERL+E GNINTSL TLG+CI  L+ +++++
Sbjct: 365 SEMSRVIRVSELSLCDLAGSERTMKTQNEGERLRETGNINTSLLTLGKCINVLKNSEKSK 424

Query: 452 SKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAP 511
            +Q+ VPFR+SKLT  FQ FF G+G+ CMIVN++ C   YDETL+V KFSAIA ++    
Sbjct: 425 FQQH-VPFRESKLTHYFQSFFNGKGKICMIVNISQCYLAYDETLNVLKFSAIAQKVCVPD 483

Query: 512 PMQLGFPSLHSFIK-------------------------EHSLQ-------VSPSLEKGA 539
            +      L   +K                         E+SL+       +   LE   
Sbjct: 484 TLNSSQEKLFGPVKSSQDVSLDSNSNSKILNVKRATISWENSLEDLMEDEDLVEELENAE 543

Query: 540 KADTG----LDDDI-----ENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRD 590
           +        LD+D+     EN+A IS   K +LL ++E +K  L+ E++EKL LE  +R+
Sbjct: 544 ETQNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIRE 603

Query: 591 EICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEE 650
           E+  E  +   QRE    E L  ++E+LEE  E +L I K+ +      +   R+E  ++
Sbjct: 604 EVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLV-----GKCDTREEAAKD 658

Query: 651 LEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEEL 710
           + A   E  +                    A +    +  ++KA+L + K EL  T EEL
Sbjct: 659 ICATKVETEE--------------------ATACLELKFNQIKAELAKTKGELIKTKEEL 698

Query: 711 HK 712
            K
Sbjct: 699 KK 700



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 107/556 (19%), Positives = 220/556 (39%), Gaps = 108/556 (19%)

Query: 307  EIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDA---EEAWKLLKVGR 363
            E+  ++++   E    ++K  TL     Q  + Y   +  +HVQ +   E+  K++K+  
Sbjct: 867  ELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSN 926

Query: 364  KNQSFASTHLNQNSSRSHSIFSIRILHLQGEG----DIVPKISELSLCDLAGSERCKDQK 419
            + ++          S ++++  I+++H + +     D V +IS + L +L      +D  
Sbjct: 927  EIET-------ATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNL------RDLS 973

Query: 420  SGERLKEAGNI-NTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRS 478
            +G    E  N+ NT L  LG      +Q ++ R ++   P R++      +         
Sbjct: 974  NGS---EEDNLPNTQLDLLGNDYLVSKQVKEYRIQE---PNRENSFHSSIEAI------- 1020

Query: 479  CMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKG 538
                        ++E   + K S+  S  +     Q+    L + +K +  + +   EK 
Sbjct: 1021 ------------WEECKEIVKASSKKSHQIEELEQQI--EKLQAEVKGYKDENNRLKEKE 1066

Query: 539  AKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEIC----- 593
             K     DD ++ +  +    KEEL +    +   +    + K  L    +   C     
Sbjct: 1067 HKNQ---DDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKI 1123

Query: 594  NEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQ--------------- 638
             E+   ++ ++  CS     ++++LE+  E  +  L+ +L  F +               
Sbjct: 1124 KELETILETQKVECSHSAKLEQDILEK--ESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1181

Query: 639  -----EEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVK 693
                 EEI +    +++++ LLQ   ++   ++Q   +L      +   SAS+ + Q +K
Sbjct: 1182 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKL------KEELSASSARTQNLK 1235

Query: 694  AKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDK------------------KLE 735
            A LQ+ + +     E+L   +K ++          D DK                  +L+
Sbjct: 1236 ADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELD 1295

Query: 736  EGQKNIRLLRTEL--QKLGESLQSAERACCHSTGAGK----LRQALTTCDDILIKQDQTL 789
              Q+ I+ L+ +L  QK+ E++Q  ERAC       K    +R  L   +   ++QDQ L
Sbjct: 1296 MKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVL 1355

Query: 790  AELQNNMVLVKLDLRK 805
                  +  +  +L K
Sbjct: 1356 EAKLEEVERLATELEK 1371



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 52/258 (20%), Positives = 109/258 (42%), Gaps = 44/258 (17%)

Query: 612  DTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSE 671
            +TQ +LL   Y     ++ + +  +  +E    +     +EA+ +E ++   A  +   +
Sbjct: 983  NTQLDLLGNDY-----LVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQ 1037

Query: 672  LALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQ-----------KMLEPP 720
            +              QQ+++++A+++  K E N   E+ HK Q           + L+  
Sbjct: 1038 I----------EELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEE 1087

Query: 721  PSAKPFTIDVD--------KKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLR 772
               K  T+DV         + L E  + +   + ++++L   L++ +  C HS    KL 
Sbjct: 1088 LQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHS---AKLE 1144

Query: 773  QALTTCDDILIKQDQTLAELQNNM---VLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKR 829
            Q +   + I++K ++ L E Q ++   V    DL  K   + E+   + +L   +   K 
Sbjct: 1145 QDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEE---ITQLTNNLQDMKH 1201

Query: 830  -LGTNQENQQPNQQPPGK 846
             L   +E ++ N+Q   K
Sbjct: 1202 LLQLKEEEEETNRQETEK 1219



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 37/172 (21%), Positives = 91/172 (52%), Gaps = 18/172 (10%)

Query: 549  IENEADISMYGKEELLQV----VEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQ-MQQR 603
            ++ E  + M  +++LL++    +E  K    +E   K +    L++++ N+ VE+ +QQ 
Sbjct: 1262 VQKEVSV-MRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQY 1320

Query: 604  EQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSV 663
            E+ C + L+ +++++E+M   ++ + ++  T   Q+++ E   K+EE+E L  E  +   
Sbjct: 1321 ERACKD-LNVKEKIIEDM---RMTLEEQEQTQVEQDQVLE--AKLEEVERLATELEK--- 1371

Query: 664  AHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQK 715
              ++  ++L  + +QR  ++   +   +V  KL   + EL  + ++ +  +K
Sbjct: 1372 -WKEKCNDLETKNNQR--SNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 1420


>gi|20143967 kinesin family member 23 isoform 1 [Homo sapiens]
          Length = 960

 Score =  253 bits (645), Expect = 7e-67
 Identities = 219/759 (28%), Positives = 358/759 (47%), Gaps = 99/759 (13%)

Query: 63  EKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFT 122
           + V VY RVRPL        + + C+ + N  T+ L  P+     + N  G  + T +++
Sbjct: 24  DPVGVYCRVRPL-----GFPDQECCIEVINNTTVQLHTPE---GYRLNRNGDYKET-QYS 74

Query: 123 FSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPR 182
           F Q+FG    Q   F++    +V D++ G+N L++TYGVT SGKTHT+ G+  +GG+LPR
Sbjct: 75  FKQVFGTHTTQKELFDVVANPLVNDLIHGKNGLLFTYGVTGSGKTHTMTGSPGEGGLLPR 134

Query: 183 SLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLK 242
            L +IFNS+          K   SN+    +S  I+ E    L            ++S K
Sbjct: 135 CLDMIFNSIGSFQAKRYVFK---SND---RNSMDIQCEVDALLERQKREAMPNPKTSSSK 188

Query: 243 RSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFSIW 302
           R V            D   A + ++ +   + ++DE S                  + ++
Sbjct: 189 RQV------------DPEFADMITVQEFCKAEEVDEDSV-----------------YGVF 219

Query: 303 ISFFEIYNELLYDLLEP----PSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           +S+ EIYN  +YDLLE     P + +  Q+  L ED+N N YV     + V+  EEA+++
Sbjct: 220 VSYIEIYNNYIYDLLEEVPFDPIKPKPPQSKLLREDKNHNMYVAGCTEVEVKSTEEAFEV 279

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILH--LQGEGDIVPK------ISELSLCDLA 410
              G+K +  A+THLN+ SSRSHS+F+I+++   L  +GD V +      IS+LSL DLA
Sbjct: 280 FWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLVDLA 339

Query: 411 GSERC-KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQ 469
           GSER  + +  G RL+EAGNIN SL TL  C+  LR+NQ   + + +VP+RDSKLT +F+
Sbjct: 340 GSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTNK-MVPYRDSKLTHLFK 398

Query: 470 GFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSL--------- 520
            +F G G+  MIV VNP A  Y+E L V +F+ +  ++  A P+      L         
Sbjct: 399 NYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARPVDKAICGLTPGRRYRNQ 458

Query: 521 -------HSFIKEHSLQVSPSLEKGAKADTG-------LDDDIENEADISMYGKEELLQV 566
                     + +  LQ  P L      D         L + +E   ++     +E  + 
Sbjct: 459 PRGPVGNEPLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQMMIDEFNKQ 518

Query: 567 VEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYE--E 624
             A K LL +     L  E H++ ++ NE  E+M   ++   E L+ + + LE   E  E
Sbjct: 519 SNAFKALLQEFDNAVLSKENHMQGKL-NEK-EKMISGQKLEIERLEKKNKTLEYKIEILE 576

Query: 625 KLNILKESLTSFYQEEIQERDEKIE-------ELEALLQEARQQSVAHQQSGSELALRRS 677
           K   + E      Q+E++ +++K++        LEA LQ    ++    +   E  +   
Sbjct: 577 KTTTIYEEDKRNLQQELETQNQKLQRQFSDKRRLEARLQGMVTETTMKWEKECERRVAAK 636

Query: 678 QRLAAS---ASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLE--PPPSAKPFTIDVDK 732
           Q    +      ++L+++KA + + K E           +K+ +    PS  P + +   
Sbjct: 637 QLEMQNKLWVKDEKLKQLKAIVTEPKTEKPERPSRERDREKVTQRSVSPSPVPLSSNYIA 696

Query: 733 KLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKL 771
           ++  GQ+   + + +L +   S  S   A C S    K+
Sbjct: 697 QISNGQQ--LMSQPQLHRRSNSCSSISVASCISEWEQKI 733


>gi|6754472 kinesin family member 23 isoform 2 [Homo sapiens]
          Length = 856

 Score =  250 bits (638), Expect = 5e-66
 Identities = 210/703 (29%), Positives = 338/703 (48%), Gaps = 100/703 (14%)

Query: 63  EKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFT 122
           + V VY RVRPL        + + C+ + N  T+ L  P+     + N  G  + T +++
Sbjct: 24  DPVGVYCRVRPL-----GFPDQECCIEVINNTTVQLHTPE---GYRLNRNGDYKET-QYS 74

Query: 123 FSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPR 182
           F Q+FG    Q   F++    +V D++ G+N L++TYGVT SGKTHT+ G+  +GG+LPR
Sbjct: 75  FKQVFGTHTTQKELFDVVANPLVNDLIHGKNGLLFTYGVTGSGKTHTMTGSPGEGGLLPR 134

Query: 183 SLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLK 242
            L +IFNS+          K   SN+    +S  I+ E    L            ++S K
Sbjct: 135 CLDMIFNSIGSFQAKRYVFK---SND---RNSMDIQCEVDALLERQKREAMPNPKTSSSK 188

Query: 243 RSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFSIW 302
           R V            D   A + ++ +   + ++DE S                  + ++
Sbjct: 189 RQV------------DPEFADMITVQEFCKAEEVDEDSV-----------------YGVF 219

Query: 303 ISFFEIYNELLYDLLEP----PSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           +S+ EIYN  +YDLLE     P + +  Q+  L ED+N N YV     + V+  EEA+++
Sbjct: 220 VSYIEIYNNYIYDLLEEVPFDPIKPKPPQSKLLREDKNHNMYVAGCTEVEVKSTEEAFEV 279

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILH--LQGEGDIVPK------ISELSLCDLA 410
              G+K +  A+THLN+ SSRSHS+F+I+++   L  +GD V +      IS+LSL DLA
Sbjct: 280 FWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLVDLA 339

Query: 411 GSERC-KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQ 469
           GSER  + +  G RL+EAGNIN SL TL  C+  LR+NQ   + + +VP+RDSKLT +F+
Sbjct: 340 GSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTNK-MVPYRDSKLTHLFK 398

Query: 470 GFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSL--------- 520
            +F G G+  MIV VNP A  Y+E L V +F+ +  ++  A P+      L         
Sbjct: 399 NYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARPVDKAICGLTPGRRYRNQ 458

Query: 521 -------HSFIKEHSLQVSPSLEKGAKADTG-------LDDDIENEADISMYGKEELLQV 566
                     + +  LQ  P L      D         L + +E   ++     +E  + 
Sbjct: 459 PRGPVGNEPLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQMMIDEFNKQ 518

Query: 567 VEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKL 626
             A K LL +     L  E H++ ++ NE  E+M   ++   E L+ + + L    E K+
Sbjct: 519 SNAFKALLQEFDNAVLSKENHMQGKL-NEK-EKMISGQKLEIERLEKKNKTL----EYKI 572

Query: 627 NILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASAST 686
            IL E  T+ Y+E+ +   +++        E + Q +  Q S       R Q +    + 
Sbjct: 573 EIL-EKTTTIYEEDKRNLQQEL--------ETQNQKLQRQFSDKRRLEARLQGMVTETTM 623

Query: 687 QQLQE----VKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKP 725
           +  +E    V AK  + + +L    E+L + + ++  P + KP
Sbjct: 624 KWEKECERRVAAKQLEMQNKLWVKDEKLKQLKAIVTEPKTEKP 666


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score =  155 bits (393), Expect = 1e-37
 Identities = 119/440 (27%), Positives = 218/440 (49%), Gaps = 43/440 (9%)

Query: 298 RFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWK 357
           RF + +S+ EIYNE + DLL     QR    L + E  +   Y+KDL+   V +A++  +
Sbjct: 142 RFLVRVSYLEIYNEEVRDLLGKDQTQR----LEVKERPDVGVYIKDLSAYVVNNADDMDR 197

Query: 358 LLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQG--EGDIVPKISELSLCDLAGSER- 414
           ++ +G KN+S  +T++N++SSRSH+IF+I I   +   +G++  ++ +L L DLAGSER 
Sbjct: 198 IMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQ 257

Query: 415 CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
            K   +G+RLKEA  IN SL TLG  I+AL        K   VP+R+SKLTR+ Q    G
Sbjct: 258 AKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKSTHVPYRNSKLTRLLQDSLGG 312

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQL-----VHAPPMQLGFPSLHSFIKEHSL 529
             ++ M  N+ P    YDET+   +++  A  +     ++  P           I+E   
Sbjct: 313 NSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKK 372

Query: 530 QVSPSLEKGAKADTGLDDDIENEADI--------SMYGKEELLQVVEAMKTLLLKERQEK 581
           ++    E      +G ++D + E ++           GK+++           + E ++ 
Sbjct: 373 KLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKA 432

Query: 582 LQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNIL------------ 629
           L+ ++ + +E  N+   ++++RE+   +     + LLE++   +  ++            
Sbjct: 433 LETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEE 492

Query: 630 KESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQL 689
           +E L      E++ER ++ E+L   L+E  Q+ +  ++  + L      +  A   T++L
Sbjct: 493 QEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSL------QEEAQGKTKKL 546

Query: 690 QEVKAKLQQCKAELNSTTEE 709
           ++V   L   K+E+    +E
Sbjct: 547 KKVWTMLMAAKSEMADLQQE 566



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 47/135 (34%), Positives = 67/135 (49%), Gaps = 13/135 (9%)

Query: 60  DSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATH 119
           +S + VKV +R RPL   E      Q  V ++ +   +     DS    SNE        
Sbjct: 10  ESCDNVKVVVRCRPLNEREKSMCYKQA-VSVDEMRGTITVHKTDS----SNE-----PPK 59

Query: 120 RFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGT---IKD 176
            FTF  +FGPE  Q   +NLT + ++  VL+G N  I+ YG T +GKT T++G     + 
Sbjct: 60  TFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPEL 119

Query: 177 GGILPRSLALIFNSL 191
            GI+P S A IF  +
Sbjct: 120 RGIIPNSFAHIFGHI 134


>gi|46852172 kinesin family member 13B [Homo sapiens]
          Length = 1826

 Score =  152 bits (384), Expect = 1e-36
 Identities = 107/314 (34%), Positives = 161/314 (51%), Gaps = 38/314 (12%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           F + +S+ EIYNE + DLL+P      RQTL++ E     PYV  L+ + V   ++   L
Sbjct: 144 FKVEVSYMEIYNEKVRDLLDPKGS---RQTLKVREHSVLGPYVDGLSKLAVTSYKDIESL 200

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGE---GDIVPKISELSLCDLAGSERC 415
           +  G K+++ A+T++N+ SSRSH++F I + H   +   G    K+ +LSL DLAGSER 
Sbjct: 201 MSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERA 260

Query: 416 -KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
            K   +G+RLKE  NIN SL TLG  I+AL      ++K   VP+RDS LT + +    G
Sbjct: 261 TKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGG 320

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPS 534
             ++ M+  V+P A  YDETL   +++  A  +V+           H+ + E        
Sbjct: 321 NSKTAMVATVSPAADNYDETLSTLRYADRAKHIVN-----------HAVVNE-------- 361

Query: 535 LEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKER---QEKLQLEMHLRDE 591
            +  A+    L +++E           E L   EAMK+  LK+R    EKL  EM +  E
Sbjct: 362 -DPNARIIRDLREEVEK--------LREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWE 412

Query: 592 ICNEMVEQMQQREQ 605
                 E++ Q  Q
Sbjct: 413 EKLRKTEEIAQERQ 426



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 45/171 (26%), Positives = 74/171 (43%), Gaps = 21/171 (12%)

Query: 64  KVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTF 123
           KVKV +R+RP+   E +      CV   +   ++L  P ++   K + RG  +    F +
Sbjct: 5   KVKVAVRIRPMNRRETDLHTK--CVVDVDANKVILN-PVNTNLSKGDARGQPKV---FAY 58

Query: 124 SQIFGPE--------VGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIK 175
              F            GQ   F    + ++++   G N  I+ YG T SGK++T+ GT  
Sbjct: 59  DHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTAD 118

Query: 176 DGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIW-------LDSKQIRQ 219
             G++PR  + +F   Q + +     K  +S   I+       LD K  RQ
Sbjct: 119 QPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQ 169



 Score = 30.0 bits (66), Expect = 10.0
 Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 1/88 (1%)

Query: 612 DTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSE 671
           D    ++ ++ EE +  L+E LT     +  E  +++EE E L+QE         +   E
Sbjct: 362 DPNARIIRDLREE-VEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE 420

Query: 672 LALRRSQRLAASASTQQLQEVKAKLQQC 699
           +A  R ++L +   + Q   +K    +C
Sbjct: 421 IAQERQKQLESLGISLQSSGIKVGDDKC 448


>gi|4758646 kinesin family member 3B [Homo sapiens]
          Length = 747

 Score =  150 bits (379), Expect = 5e-36
 Identities = 135/454 (29%), Positives = 224/454 (49%), Gaps = 49/454 (10%)

Query: 296 NIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           N ++ +  S+ EIY E + DLL     +R    L L E  +   YVKDL+    +  +E 
Sbjct: 135 NQQYLVRASYLEIYQEEIRDLLSKDQTKR----LELKERPDTGVYVKDLSSFVTKSVKEI 190

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRI----LHLQGEGDIVPKISELSLCDLAG 411
             ++ VG +N+S  +T++N++SSRSH+IF I I    + L GE  I  ++ +L+L DLAG
Sbjct: 191 EHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHI--RVGKLNLVDLAG 248

Query: 412 SER-CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQG 470
           SER  K    GERLKEA  IN SL  LG  I+AL        K   +P+RDSKLTR+ Q 
Sbjct: 249 SERQAKTGAQGERLKEATKINLSLSALGNVISALVD-----GKSTHIPYRDSKLTRLLQD 303

Query: 471 FFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPM-QLGFPSLHSFIKEHSL 529
              G  ++ M+ NV P +   +ETL   +++  A  + + P + +    +L    +E   
Sbjct: 304 SLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIA 363

Query: 530 QVSPSLEKGA----------KADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQ 579
           ++   LEK +          +   G     E E +    G+EE        K    +E+Q
Sbjct: 364 RLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEE-----GDDKDDYWREQQ 418

Query: 580 EKLQLEMHLRDE----ICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESL-- 633
           EKL++E     E    +  E +  ++++E+   E L  +K+   EM   K+  ++  L  
Sbjct: 419 EKLEIEKRAIVEDHSLVAEEKMRLLKEKEK-KMEDLRREKD-AAEMLGAKIKAMESKLLV 476

Query: 634 --------TSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSEL-ALRRSQRLAASA 684
                   T+  Q+ ++++ ++I E +   +E +QQ  +  +   EL     S +     
Sbjct: 477 GGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDI 536

Query: 685 STQQLQEVKAKLQQCKAELNSTTEELHKYQKMLE 718
            T++L+++ +KLQ  KAE++   EE  K ++ LE
Sbjct: 537 KTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELE 570



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 48/195 (24%), Positives = 95/195 (48%), Gaps = 23/195 (11%)

Query: 61  SMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHR 120
           S E V+V +R RP+   E     D    ++ +V+  + Q      ++K+ +    +    
Sbjct: 6   SSESVRVVVRCRPMNGKEKAASYD----KVVDVDVKLGQV-----SVKNPKGTAHEMPKT 56

Query: 121 FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKD---G 177
           FTF  ++     Q   ++ T + +V  VL+G N  I+ YG T +GKT+T++G   D    
Sbjct: 57  FTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR 116

Query: 178 GILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIR----QEEMKKLSLL---NG 230
           G++P S   IF      +  + + + L+    + +  ++IR    +++ K+L L    + 
Sbjct: 117 GVIPNSFDHIFT----HISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDT 172

Query: 231 GLQEEELSTSLKRSV 245
           G+  ++LS+ + +SV
Sbjct: 173 GVYVKDLSSFVTKSV 187


>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
          Length = 1749

 Score =  149 bits (377), Expect = 9e-36
 Identities = 109/326 (33%), Positives = 168/326 (51%), Gaps = 38/326 (11%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           F + +S+ EIYNE + DLL+P      RQ+L++ E +   PYV  L+ + V   E+   L
Sbjct: 143 FKVEVSYMEIYNEKVRDLLDPKGS---RQSLKVREHKVLGPYVDGLSQLAVTSFEDIESL 199

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRI---LHLQGEGDIVPKISELSLCDLAGSERC 415
           +  G K+++ A+T++N+ SSRSH++F+I I   L+    G+   K+S++SL DLAGSER 
Sbjct: 200 MSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGEKVSKVSLVDLAGSERV 259

Query: 416 -KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
            K   +GERLKE  NIN SL TLG  I++L      + K   VP+RDS LT + +    G
Sbjct: 260 SKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGG 319

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPS 534
             ++ MI  ++P A  Y+ETL   +++  A ++V+           H+ + E        
Sbjct: 320 NSQTSMIATISPAADNYEETLSTLRYADRAKRIVN-----------HAVVNE-------- 360

Query: 535 LEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKER---QEKLQLEMHLRDE 591
            +  AK    L +++E           E L   EAMK   LKE+    EKL  E+ +  E
Sbjct: 361 -DPNAKVIRELREEVEK--------LREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE 411

Query: 592 ICNEMVEQMQQREQWCSEHLDTQKEL 617
                 E++ Q  Q   E +    E+
Sbjct: 412 EKLRKTEEIAQERQRQLESMGISLEM 437



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 22/171 (12%)

Query: 64  KVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTF 123
           KVKV +RVRP+   ELE    +  V +E  +T++   P ++   K  ER   +    F F
Sbjct: 5   KVKVAVRVRPMNRRELELNT-KCVVEMEGNQTVLHPPPSNT---KQGER---KPPKVFAF 57

Query: 124 SQIFGPE--------VGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIK 175
              F            GQ   F    + +++   +G N  I+ YG T SGK+ ++ G  +
Sbjct: 58  DYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 176 DGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIW-------LDSKQIRQ 219
             G++PR    +F  +  + + +   K  +S   I+       LD K  RQ
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ 168



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 612 DTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSE 671
           D   +++ E+ EE +  L+E L+     +  E  EK+EE E L++E         +   E
Sbjct: 361 DPNAKVIRELREE-VEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEE 419

Query: 672 LALRRSQRLAASASTQQLQEVKAKLQQC 699
           +A  R ++L +   + ++  +K    +C
Sbjct: 420 IAQERQRQLESMGISLEMSGIKVGDDKC 447


>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
          Length = 1757

 Score =  149 bits (377), Expect = 9e-36
 Identities = 109/326 (33%), Positives = 168/326 (51%), Gaps = 38/326 (11%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           F + +S+ EIYNE + DLL+P      RQ+L++ E +   PYV  L+ + V   E+   L
Sbjct: 143 FKVEVSYMEIYNEKVRDLLDPKGS---RQSLKVREHKVLGPYVDGLSQLAVTSFEDIESL 199

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRI---LHLQGEGDIVPKISELSLCDLAGSERC 415
           +  G K+++ A+T++N+ SSRSH++F+I I   L+    G+   K+S++SL DLAGSER 
Sbjct: 200 MSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGEKVSKVSLVDLAGSERV 259

Query: 416 -KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
            K   +GERLKE  NIN SL TLG  I++L      + K   VP+RDS LT + +    G
Sbjct: 260 SKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGG 319

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPS 534
             ++ MI  ++P A  Y+ETL   +++  A ++V+           H+ + E        
Sbjct: 320 NSQTSMIATISPAADNYEETLSTLRYADRAKRIVN-----------HAVVNE-------- 360

Query: 535 LEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKER---QEKLQLEMHLRDE 591
            +  AK    L +++E           E L   EAMK   LKE+    EKL  E+ +  E
Sbjct: 361 -DPNAKVIRELREEVEK--------LREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE 411

Query: 592 ICNEMVEQMQQREQWCSEHLDTQKEL 617
                 E++ Q  Q   E +    E+
Sbjct: 412 EKLRKTEEIAQERQRQLESMGISLEM 437



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 22/171 (12%)

Query: 64  KVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTF 123
           KVKV +RVRP+   ELE    +  V +E  +T++   P ++   K  ER   +    F F
Sbjct: 5   KVKVAVRVRPMNRRELELNT-KCVVEMEGNQTVLHPPPSNT---KQGER---KPPKVFAF 57

Query: 124 SQIFGPE--------VGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIK 175
              F            GQ   F    + +++   +G N  I+ YG T SGK+ ++ G  +
Sbjct: 58  DYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 176 DGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIW-------LDSKQIRQ 219
             G++PR    +F  +  + + +   K  +S   I+       LD K  RQ
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ 168



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 612 DTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSE 671
           D   +++ E+ EE +  L+E L+     +  E  EK+EE E L++E         +   E
Sbjct: 361 DPNAKVIRELREE-VEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEE 419

Query: 672 LALRRSQRLAASASTQQLQEVKAKLQQC 699
           +A  R ++L +   + ++  +K    +C
Sbjct: 420 IAQERQRQLESMGISLEMSGIKVGDDKC 447


>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
          Length = 1770

 Score =  149 bits (377), Expect = 9e-36
 Identities = 109/326 (33%), Positives = 168/326 (51%), Gaps = 38/326 (11%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           F + +S+ EIYNE + DLL+P      RQ+L++ E +   PYV  L+ + V   E+   L
Sbjct: 143 FKVEVSYMEIYNEKVRDLLDPKGS---RQSLKVREHKVLGPYVDGLSQLAVTSFEDIESL 199

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRI---LHLQGEGDIVPKISELSLCDLAGSERC 415
           +  G K+++ A+T++N+ SSRSH++F+I I   L+    G+   K+S++SL DLAGSER 
Sbjct: 200 MSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGEKVSKVSLVDLAGSERV 259

Query: 416 -KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
            K   +GERLKE  NIN SL TLG  I++L      + K   VP+RDS LT + +    G
Sbjct: 260 SKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGG 319

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPS 534
             ++ MI  ++P A  Y+ETL   +++  A ++V+           H+ + E        
Sbjct: 320 NSQTSMIATISPAADNYEETLSTLRYADRAKRIVN-----------HAVVNE-------- 360

Query: 535 LEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKER---QEKLQLEMHLRDE 591
            +  AK    L +++E           E L   EAMK   LKE+    EKL  E+ +  E
Sbjct: 361 -DPNAKVIRELREEVEK--------LREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE 411

Query: 592 ICNEMVEQMQQREQWCSEHLDTQKEL 617
                 E++ Q  Q   E +    E+
Sbjct: 412 EKLRKTEEIAQERQRQLESMGISLEM 437



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 22/171 (12%)

Query: 64  KVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTF 123
           KVKV +RVRP+   ELE    +  V +E  +T++   P ++   K  ER   +    F F
Sbjct: 5   KVKVAVRVRPMNRRELELNT-KCVVEMEGNQTVLHPPPSNT---KQGER---KPPKVFAF 57

Query: 124 SQIFGPE--------VGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIK 175
              F            GQ   F    + +++   +G N  I+ YG T SGK+ ++ G  +
Sbjct: 58  DYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 176 DGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIW-------LDSKQIRQ 219
             G++PR    +F  +  + + +   K  +S   I+       LD K  RQ
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ 168



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 612 DTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSE 671
           D   +++ E+ EE +  L+E L+     +  E  EK+EE E L++E         +   E
Sbjct: 361 DPNAKVIRELREE-VEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEE 419

Query: 672 LALRRSQRLAASASTQQLQEVKAKLQQC 699
           +A  R ++L +   + ++  +K    +C
Sbjct: 420 IAQERQRQLESMGISLEMSGIKVGDDKC 447


>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
          Length = 1805

 Score =  149 bits (377), Expect = 9e-36
 Identities = 109/326 (33%), Positives = 168/326 (51%), Gaps = 38/326 (11%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           F + +S+ EIYNE + DLL+P      RQ+L++ E +   PYV  L+ + V   E+   L
Sbjct: 143 FKVEVSYMEIYNEKVRDLLDPKGS---RQSLKVREHKVLGPYVDGLSQLAVTSFEDIESL 199

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRI---LHLQGEGDIVPKISELSLCDLAGSERC 415
           +  G K+++ A+T++N+ SSRSH++F+I I   L+    G+   K+S++SL DLAGSER 
Sbjct: 200 MSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGEKVSKVSLVDLAGSERV 259

Query: 416 -KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
            K   +GERLKE  NIN SL TLG  I++L      + K   VP+RDS LT + +    G
Sbjct: 260 SKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGG 319

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPS 534
             ++ MI  ++P A  Y+ETL   +++  A ++V+           H+ + E        
Sbjct: 320 NSQTSMIATISPAADNYEETLSTLRYADRAKRIVN-----------HAVVNE-------- 360

Query: 535 LEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKER---QEKLQLEMHLRDE 591
            +  AK    L +++E           E L   EAMK   LKE+    EKL  E+ +  E
Sbjct: 361 -DPNAKVIRELREEVEK--------LREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE 411

Query: 592 ICNEMVEQMQQREQWCSEHLDTQKEL 617
                 E++ Q  Q   E +    E+
Sbjct: 412 EKLRKTEEIAQERQRQLESMGISLEM 437



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 22/171 (12%)

Query: 64  KVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTF 123
           KVKV +RVRP+   ELE    +  V +E  +T++   P ++   K  ER   +    F F
Sbjct: 5   KVKVAVRVRPMNRRELELNT-KCVVEMEGNQTVLHPPPSNT---KQGER---KPPKVFAF 57

Query: 124 SQIFGPE--------VGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIK 175
              F            GQ   F    + +++   +G N  I+ YG T SGK+ ++ G  +
Sbjct: 58  DYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 176 DGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIW-------LDSKQIRQ 219
             G++PR    +F  +  + + +   K  +S   I+       LD K  RQ
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ 168



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 612 DTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSE 671
           D   +++ E+ EE +  L+E L+     +  E  EK+EE E L++E         +   E
Sbjct: 361 DPNAKVIRELREE-VEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEE 419

Query: 672 LALRRSQRLAASASTQQLQEVKAKLQQC 699
           +A  R ++L +   + ++  +K    +C
Sbjct: 420 IAQERQRQLESMGISLEMSGIKVGDDKC 447


>gi|13699824 kinesin family member 11 [Homo sapiens]
          Length = 1056

 Score =  140 bits (352), Expect = 7e-33
 Identities = 113/367 (30%), Positives = 194/367 (52%), Gaps = 33/367 (8%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNP--YVKDLNWIHVQDAEEAW 356
           FS+ +S  EIYNE L+DLL P S   +R  L++ +D        +K L  I V + +E +
Sbjct: 154 FSVKVSLLEIYNEELFDLLNPSSDVSER--LQMFDDPRNKRGVIIKGLEEITVHNKDEVY 211

Query: 357 KLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQG---EGDIVPKISELSLCDLAGSE 413
           ++L+ G   ++ A+T +N  SSRSHS+FS+ I H++    +G+ + KI +L+L DLAGSE
Sbjct: 212 QILEKGAAKRTTAATLMNAYSSRSHSVFSVTI-HMKETTIDGEELVKIGKLNLVDLAGSE 270

Query: 414 RC-KDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFF 472
              +     +R +EAGNIN SL TLGR I AL +   +      VP+R+SKLTR+ Q   
Sbjct: 271 NIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPH------VPYRESKLTRILQDSL 324

Query: 473 TGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVS 532
            GR R+ +I  ++P +   +ETL   +++  A  +++ P +     +  + IKE++ ++ 
Sbjct: 325 GGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKL-TKKALIKEYTEEIE 383

Query: 533 PSLEKGAKADTGLDDDIENEADISMYGK-----EELLQVVEAMKTLLLKERQEKLQLEMH 587
                 A A       I  E    M GK     E++++++E +   + +E     +L M 
Sbjct: 384 RLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGA-VEEELNRVTELFMD 442

Query: 588 LRDEI--CNEMVEQMQQREQWCSEHL-DTQKELLEEMY--------EEKLNILKESLTSF 636
            ++E+  C   ++   Q  +   +HL +T+ +L++E Y        EEKL+     L + 
Sbjct: 443 NKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNT 502

Query: 637 YQEEIQE 643
            +E  ++
Sbjct: 503 VEETTKD 509



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 11/82 (13%)

Query: 121 FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKD---- 176
           +TF  +FG    Q   +   V  ++ +V+ G N  I+ YG T +GKT T++G        
Sbjct: 66  YTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEY 125

Query: 177 -------GGILPRSLALIFNSL 191
                   GI+PR+L  IF  L
Sbjct: 126 TWEEDPLAGIIPRTLHQIFEKL 147



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 12/109 (11%)

Query: 613 TQKELLEEMYEEKLNILKESLTSFYQEE---IQERDEKIEELEALLQEARQQSVAHQQSG 669
           T+K L++E Y E++  LK  L +  ++    I E + ++   +  +QE +   +  +   
Sbjct: 370 TKKALIKE-YTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGA 428

Query: 670 SELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLE 718
            E  L R         T+   + K +L QCK++L + T+EL   QK L+
Sbjct: 429 VEEELNRV--------TELFMDNKNELDQCKSDLQNKTQELETTQKHLQ 469


>gi|116686122 kinesin family member 4 [Homo sapiens]
          Length = 1232

 Score =  137 bits (344), Expect = 6e-32
 Identities = 127/476 (26%), Positives = 228/476 (47%), Gaps = 28/476 (5%)

Query: 295 ANIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEE 354
           ++  F++ +S+ EIYNE + DLL P    R++  + + ED      +  L    V  A +
Sbjct: 130 SDFEFTLKVSYLEIYNEEILDLLCP---SREKAQINIREDPKEGIKIVGLTEKTVLVALD 186

Query: 355 AWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSER 414
               L+ G  +++ AST +N  SSRSH+IF+I +   +         S+L L DLAGSER
Sbjct: 187 TVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSER 246

Query: 415 CKDQKS-GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFT 473
            K  K+ G+RLKE  NIN  L  LG  I+AL  ++    K   VP+RDSKLTR+ Q    
Sbjct: 247 QKKTKAEGDRLKEGININRGLLCLGNVISALGDDK----KGGFVPYRDSKLTRLLQDSLG 302

Query: 474 GRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSP 533
           G   + MI  V+P  S  +ETL+  +++  A ++ + P + +   +      +  +Q   
Sbjct: 303 GNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQ 362

Query: 534 SLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEIC 593
            L   A   T           I++   E L  ++E  ++L+  E  EKL   +       
Sbjct: 363 VLLLQAHGGT-------LPGSITVEPSENLQSLMEKNQSLV--EENEKLSRGLSEAAGQT 413

Query: 594 NEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEA 653
            +M+E++   EQ  +E ++ + E L +    KL+ L++ + +   +E++E  E I  L+ 
Sbjct: 414 AQMLERIILTEQ-ANEKMNAKLEELRQHAACKLD-LQKLVETLEDQELKENVEIICNLQQ 471

Query: 654 LLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCK-AELNSTTEELHK 712
           L+ +   ++VA   +  + A+ +  ++  S  T +  +        + A+++    EL+K
Sbjct: 472 LITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNK 531

Query: 713 --------YQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAER 760
                    +KM +     +P        ++E +  +  L+ E ++L   LQ+A++
Sbjct: 532 ALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKK 587



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 56/230 (24%), Positives = 96/230 (41%), Gaps = 33/230 (14%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           V+V LR RPL+P E+     +GC      +  +   P +   +   ++        FT+ 
Sbjct: 10  VRVALRCRPLVPKEIS----EGC------QMCLSFVPGEPQVVVGTDKS-------FTYD 52

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTI-------KDG 177
            +F P   Q   FN  V  ++K V KG N  +  YG T SGKT+++ G            
Sbjct: 53  FVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112

Query: 178 GILPRSLALIFNSLQGQLHPTPDLK----PLLSNEVIWL-----DSKQIRQEEMKKLSLL 228
           G++PR + L+F  +  +      LK     + + E++ L     +  QI   E  K  + 
Sbjct: 113 GVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIK 172

Query: 229 NGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDE 278
             GL E+ +  +L     +E    + T   + +   SS S    +  L++
Sbjct: 173 IVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQ 222


>gi|150010604 kinesin family member 4B [Homo sapiens]
          Length = 1234

 Score =  135 bits (341), Expect = 1e-31
 Identities = 124/477 (25%), Positives = 226/477 (47%), Gaps = 19/477 (3%)

Query: 295 ANIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEE 354
           ++  F++ +S+ EIYNE + DLL P    R++  + + ED      +  L    V  A +
Sbjct: 130 SDFEFTLKVSYLEIYNEEILDLLCP---SREKAQINIREDPKEGIKIVGLTEKTVLVALD 186

Query: 355 AWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSER 414
               L+ G  +++ AST +N  SSRSH+IF+I I   +         S+L L DLAGSER
Sbjct: 187 TVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVDLAGSER 246

Query: 415 CKDQKS-GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFT 473
            K  K+ G+RLKE  NIN  L  LG  I+AL  ++    K + VP+RDSKLTR+ Q    
Sbjct: 247 QKKTKAEGDRLKEGININRGLLCLGNVISALGDDK----KGSFVPYRDSKLTRLLQDSLG 302

Query: 474 GRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSL---HSFIKEHSLQ 530
           G   + MI  V+P  S  +ETL   +++  A ++ + P + +   +    H   +   LQ
Sbjct: 303 GNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQ 362

Query: 531 VSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQL--EMHL 588
           V      G      ++ +        M   + L++  E +   L K   +  Q+   + L
Sbjct: 363 VLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIIL 422

Query: 589 RDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKI 648
            +++  ++  ++++  Q  +  LD QK L+E + +++L    E + +  Q   Q  DE +
Sbjct: 423 TEQVNEKLNAKLEELRQHVACKLDLQK-LVETLEDQELKENVEIICNLQQLITQLSDETV 481

Query: 649 ----EELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELN 704
                 ++  ++E  Q   + + S S  A      L  +  ++++ E+   L   +A + 
Sbjct: 482 ACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVR 541

Query: 705 STTEELHKYQKM-LEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAER 760
             T+  ++ Q +  +   + K   ++V    +E ++ +R L+T  + + ++  S  R
Sbjct: 542 KMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHR 598



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 59/215 (27%), Positives = 91/215 (42%), Gaps = 37/215 (17%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           V+V LR RPL+P E+  +  Q C+     ET V+     SF                T+ 
Sbjct: 10  VRVALRCRPLVPKEIS-EGCQMCLSFVPGETQVVVGTDKSF----------------TYD 52

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTI-------KDG 177
            +F P   Q   FN  V  ++K + KG N  +  YG T SGKT+++ G            
Sbjct: 53  FVFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112

Query: 178 GILPRSLALIFNSLQGQLHPTPDLK----PLLSNEVIWL-----DSKQIRQEEMKKLSLL 228
           GI+PR + L+F  +  +      LK     + + E++ L     +  QI   E  K  + 
Sbjct: 113 GIIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIK 172

Query: 229 NGGLQEEELSTSLKRSVYIE----SRIGTSTSFDS 259
             GL E+ +  +L     +E    SR   ST+ +S
Sbjct: 173 IVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNS 207


>gi|9910266 kinesin family member 15 [Homo sapiens]
          Length = 1388

 Score =  135 bits (339), Expect = 2e-31
 Identities = 143/502 (28%), Positives = 233/502 (46%), Gaps = 69/502 (13%)

Query: 304 SFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGR 363
           SF EIYNE +YDLL+  S       L L E      +V       V  A EA+++L  G 
Sbjct: 165 SFIEIYNEQIYDLLDSASAG-----LYLREHIKKGVFVVGAVEQVVTSAAEAYQVLSGGW 219

Query: 364 KNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVP-KISELSLCDLAGSERCKD-QKSG 421
           +N+  AST +N+ SSRSH++F+I I  ++   +IV  + S L+L DLAGSER KD    G
Sbjct: 220 RNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVNIRTSLLNLVDLAGSERQKDTHAEG 279

Query: 422 ERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMI 481
            RLKEAGNIN SL  LG+ I AL        KQ  V +RDSKLT + +    G  ++ +I
Sbjct: 280 MRLKEAGNINRSLSCLGQVITAL--VDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAII 337

Query: 482 VNVNPCASTYDETLHVAKFS----AIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEK 537
            NV+P +  + ETL    F+     I ++ V     Q     L + +K    Q++     
Sbjct: 338 ANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKRLKEQLAELASG 397

Query: 538 GAKADTGLDDDIE--------NEADI----SMYGKEELLQVVEAMKTLLLKER---QEKL 582
               ++ L  D +         EA +    S   K+ L++ V  ++ L LK+    Q   
Sbjct: 398 QTPPESFLTRDKKKTNYMEYFQEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNK 457

Query: 583 QLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLT-------- 634
            +     D+I        + R  +  E    Q  LL E+  E +  L+E +         
Sbjct: 458 MIVKFREDQIIRLEKLHKESRGGFLPEE---QDRLLSELRNE-IQTLREQIEHHPRVAKY 513

Query: 635 SFYQEEIQERDEKIEELEAL--LQEARQQSVAHQQ------SGSELALRRSQRLAASAST 686
           +     ++E + ++  LE +   QE   Q++A  +      SG E + +  Q  +  A  
Sbjct: 514 AMENHSLREENRRLRLLEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQK 573

Query: 687 Q-----QLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQK-N 740
           +       +++KA+L Q + ELN++ +E  +++++       +   ++++ +L+  QK N
Sbjct: 574 EPCLFANTEKLKAQLLQIQTELNNSKQEYEEFKEL------TRKRQLELESELQSLQKAN 627

Query: 741 IRLLRTELQKLGESLQSAERAC 762
           + L         E+L  A +AC
Sbjct: 628 LNL---------ENLLEATKAC 640



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 43/154 (27%), Positives = 67/154 (43%), Gaps = 20/154 (12%)

Query: 43  CSVVSTSLEDKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPK 102
           C     S+ + Q     +  + +KV++R+RP  P+E     D      +N+   VL +  
Sbjct: 5   CKTELRSVTNGQSNQPSNEGDAIKVFVRIRP--PAERSGSADGE----QNLCLSVLSST- 57

Query: 103 DSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVT 162
            S  L SN          FTF  +   +  Q S F    K +V+  + G N  I+ YG T
Sbjct: 58  -SLRLHSNPE-----PKTFTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQT 111

Query: 163 NSGKTHTIQGTIKDG-------GILPRSLALIFN 189
            SGKT T+ G  +         G++PRS   +F+
Sbjct: 112 GSGKTFTMMGPSESDNFSHNLRGVIPRSFEYLFS 145



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 68/328 (20%), Positives = 124/328 (37%), Gaps = 48/328 (14%)

Query: 526  EHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLE 585
            E  +     LE+   A   +   +E   D       +L+  ++ ++T + ++ +    L+
Sbjct: 950  EQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLK 1009

Query: 586  MHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERD 645
              L+D  C      + + E            +L +  E  +  LKE+L      E  ERD
Sbjct: 1010 QELKDINCKYNSALVDREES----------RVLIKKQEVDILDLKETLRLRILSEDIERD 1059

Query: 646  EKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQ----EVKAKLQQCKA 701
               E+L    ++    + A ++    L   + +     A  Q+LQ    + K +++Q K 
Sbjct: 1060 MLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKN 1119

Query: 702  ELNSTTEEL-HKYQKMLEPPPSAKP---FTIDVDKKLEEGQKNI---RLLRTELQKLGES 754
            E N    +L H      E P S K    F   + K LE  ++ I   R  +T L+ L   
Sbjct: 1120 EYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHL--- 1176

Query: 755  LQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQY 814
                           KL +     +  +++  + L E++N        LR ++  + E+ 
Sbjct: 1177 -------------VTKLNEDREVKNAEILRMKEQLREMEN--------LRLESQQLIEKN 1215

Query: 815  HTVLKLQGQVSAKKRLGTNQENQQPNQQ 842
                 LQGQ+   KR   N +   P+ Q
Sbjct: 1216 WL---LQGQLDDIKRQKENSDQNHPDNQ 1240



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 21/161 (13%)

Query: 546  DDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQ 605
            +  ++NE + S+  +    ++VE M  L +K   E++Q  ++ ++  C  M +++++ + 
Sbjct: 1239 NQQLKNEQEESIKERLAKSKIVEEM--LKMKADLEEVQSALYNKEMECLRMTDEVERTQT 1296

Query: 606  WCSEHLDTQKEL---LEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQS 662
              S+    +++L   LEEMYEE+             E   +  E + +    L E   + 
Sbjct: 1297 LESKAFQEKEQLRSKLEEMYEER-------------ERTSQEMEMLRKQVECLAEENGKL 1343

Query: 663  VAHQ---QSGSELALRRSQRLAASASTQQLQEVKAKLQQCK 700
            V HQ   Q    +   + + +  +  T++L+     L++ K
Sbjct: 1344 VGHQNLHQKIQYVVRLKKENVRLAEETEKLRAENVFLKEKK 1384



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 38/155 (24%), Positives = 72/155 (46%), Gaps = 17/155 (10%)

Query: 616 ELLEEMYE---EKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSEL 672
           E+ E+ +E   E+L  ++E +++  Q ++ E + K  +L+  + +    S   Q+  S  
Sbjct: 706 EMNEQAFEAISEELRTVQEQMSAL-QAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSE 764

Query: 673 AL---RRSQRLAASAST--QQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPP-SAKPF 726
            +   ++ + L +  +   +QLQE + K    K+E++     LH   K L         F
Sbjct: 765 RIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSF 824

Query: 727 TIDVDK---KLEEGQKNIRL----LRTELQKLGES 754
             + +K   KL E   +++L    LR E +KL ES
Sbjct: 825 KTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLES 859


>gi|40254834 kinesin family member 1C [Homo sapiens]
          Length = 1103

 Score =  135 bits (339), Expect = 2e-31
 Identities = 83/217 (38%), Positives = 126/217 (58%), Gaps = 8/217 (3%)

Query: 295 ANIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEE 354
           A + +S+ +S+ EIY E + DLL P S    R +LR+ E     PYV+DL+ + V    +
Sbjct: 136 AQLSYSVEVSYMEIYCERVRDLLNPKS----RGSLRVREHPILGPYVQDLSKLAVTSYAD 191

Query: 355 AWKLLKVGRKNQSFASTHLNQNSSRSHSIFSI---RILHLQGEGDIVPKISELSLCDLAG 411
              L+  G K ++ A+T++N+ SSRSH++F+I   +  H Q  G    K+S++SL DLAG
Sbjct: 192 IADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKVSKISLVDLAG 251

Query: 412 SERCKDQKS-GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQG 470
           SER     + G RLKE  NIN SL TLG+ I+AL   Q  + K + +P+RDS LT + + 
Sbjct: 252 SERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKE 311

Query: 471 FFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQL 507
              G  R+ MI  ++P    Y+ETL   +++    Q+
Sbjct: 312 NLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQI 348



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/128 (30%), Positives = 58/128 (45%), Gaps = 8/128 (6%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSF-ALKSNERGIGQATHRFTF 123
           VKV +RVRP   +  E  +D  CV      T  +  PK S  A KS        +H  T 
Sbjct: 6   VKVAVRVRPF--NARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTE 63

Query: 124 SQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDG--GILP 181
              F     Q   +    +EM+    +G N  I+ YG T +GK++T+ G  + G  GI+P
Sbjct: 64  DPQFA---SQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVP 120

Query: 182 RSLALIFN 189
           +    +F+
Sbjct: 121 QLCEDLFS 128


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score =  134 bits (336), Expect = 5e-31
 Identities = 142/588 (24%), Positives = 265/588 (45%), Gaps = 72/588 (12%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           F + +S+ EIYNE + DLL      +K + L + ED N N YV DL    V  +E A K 
Sbjct: 125 FLLRVSYMEIYNETITDLL---CGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALKW 181

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDI-----VPKISELSLCDLAGSE 413
           +  G K++ +  T +NQ SSRSH+IF + IL  + +G+        K+S L+L DLAGSE
Sbjct: 182 ITKGEKSRHYGETKMNQRSSRSHTIFRM-ILESREKGEPSNCEGSVKVSHLNLVDLAGSE 240

Query: 414 R-CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFF 472
           R  +   +G RLKE  NIN SL  LG+ I  L   Q        + +RDSKLTR+ Q   
Sbjct: 241 RAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVG----GFINYRDSKLTRILQNSL 296

Query: 473 TGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVS 532
            G  ++ +I  + P   ++DETL   +F++ A  + + P +     +  + +K +  ++ 
Sbjct: 297 GGNAKTRIICTITPV--SFDETLTALQFASTAKYMKNTPYVN-EVSTDEALLKRYRKEIM 353

Query: 533 PSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQ-----LEMH 587
             L+K         +++  E       K++L Q++E  K LL K + EK++     L   
Sbjct: 354 -DLKKQL-------EEVSLETRAQAMEKDQLAQLLEE-KDLLQKVQNEKIENLTRMLVTS 404

Query: 588 LRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEI---QER 644
               +  E+  + ++R  WC   ++  K      Y ++ NI     T  ++  I   +E 
Sbjct: 405 SSLTLQQELKAKRKRRVTWCLGKINKMK---NSNYADQFNIPTNITTKTHKLSINLLREI 461

Query: 645 DEKI-----------EELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVK 693
           DE +           + L  +      + +  +   SEL   R+         +QL+  K
Sbjct: 462 DESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEK 521

Query: 694 AKLQ---------------QCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQ 738
            +++               + K + +   + +H+   +      A+ +  D++ +L    
Sbjct: 522 EEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKV 581

Query: 739 KNIRLLRTELQKLGE-----SLQSAERACCHSTGA----GKLRQALTTCDDILIKQDQTL 789
           + +R    +++KL E      L++ +    +S  +     +++Q L   + + +   +  
Sbjct: 582 ELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRES 641

Query: 790 AELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQ 837
           A L++  + +K  +++ A    +  + +   Q Q+ AKK++  + E +
Sbjct: 642 AFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKE 689



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 72/290 (24%), Positives = 134/290 (46%), Gaps = 56/290 (19%)

Query: 561  EELLQVVEAMKTLL-----LKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQK 615
            E+L Q +E +KTL      LK+ QE LQ+E   RD++ +++ + +         ++DTQ+
Sbjct: 915  EKLQQTLEEVKTLTQEKDDLKQLQESLQIE---RDQLKSDIHDTVNM-------NIDTQE 964

Query: 616  EL---LEEM--YEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGS 670
            +L   LE +  ++E +N LK  ++    EE+  R+  +EE     ++  QQ +       
Sbjct: 965  QLRNALESLKQHQETINTLKSKIS----EEV-SRNLHMEENTGETKDEFQQKMVGIDKKQ 1019

Query: 671  ELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAK-PFTID 729
            +L  + +Q L A     ++ E + K       + S  +E ++ Q+MLE   + K     D
Sbjct: 1020 DLEAKNTQTLTADVKDNEIIEQQRK-------IFSLIQEKNELQQMLESVIAEKEQLKTD 1072

Query: 730  VDKKLE---EGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQD 786
            + + +E   E Q+ +RLL  EL+K  E +   +       G     +   TCD       
Sbjct: 1073 LKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEG-----ELSRTCD------- 1120

Query: 787  QTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQEN 836
              LAE++         L++K+  + E+   +L +Q ++S  ++     EN
Sbjct: 1121 -RLAEVEEK-------LKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIEN 1162



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 69/306 (22%), Positives = 130/306 (42%), Gaps = 41/306 (13%)

Query: 525  KEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQL 584
            K H+++    L +       +++ ++ ++      +++LL V E M      E Q+K+  
Sbjct: 1105 KNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMS-----EMQKKINE 1159

Query: 585  EMHLRDEICNEMVEQMQQREQWCSEHLDTQK----ELLEEMYEEKLNILKE-----SLTS 635
              +L++E+ N+         +   EH++T++    + L E YEE  +I KE      L  
Sbjct: 1160 IENLKNELKNK---------ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQK 1210

Query: 636  FYQEEIQERDEKIEELEAL-LQEARQQSVAH------QQSGSELALRRSQRLAASASTQQ 688
             ++ E       I E+EA  LQ   +  +AH      Q++  EL    S++ A   +TQ 
Sbjct: 1211 SFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD 1270

Query: 689  LQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTEL 748
            L++   KLQ+    L+   E L   +++ E   +     +  ++   +    +  +  E 
Sbjct: 1271 LEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMER 1330

Query: 749  QKLGESLQSAERACCHSTGAGKLRQALTTCDDIL-IKQDQ-------TLAELQNNMVLVK 800
             +L E  Q ++      T   K R  L T  + L +K DQ       TLA++Q +    +
Sbjct: 1331 LRLNEKFQESQEEIKSLT---KERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQE 1387

Query: 801  LDLRKK 806
              L  K
Sbjct: 1388 QSLNMK 1393



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 77/353 (21%), Positives = 150/353 (42%), Gaps = 33/353 (9%)

Query: 491  YDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIE 550
            + ET++  K S I+ ++     M+          ++  + +    +  AK    L  D++
Sbjct: 976  HQETINTLK-SKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVK 1034

Query: 551  NEADISMYGKE-ELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSE 609
            +   I    K   L+Q    ++ +L     EK QL+  L++ I  EM  + Q+  +   +
Sbjct: 1035 DNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENI--EMTIENQEELRLLGD 1092

Query: 610  HLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSG 669
             L  Q+E++ +  E+   I KE   S   + + E +EK++E    LQE +QQ +  Q+  
Sbjct: 1093 ELKKQQEIVAQ--EKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM 1150

Query: 670  SELALRRSQRLAASASTQQLQEVKAKLQQCKAEL-NSTTEELHKYQKMLEPPPSAKPFTI 728
            SE+               +++ +K +L+  +  L +  TE L   QK+ E     K  T 
Sbjct: 1151 SEM----------QKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITK 1200

Query: 729  DVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQT 788
            +  K L+E QK+    R  L+     ++        +TG  + ++ L      L +  +T
Sbjct: 1201 E-RKVLKELQKSFETERDHLRGYIREIE--------ATGL-QTKEELKIAHIHLKEHQET 1250

Query: 789  LAELQNNM------VLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQE 835
            + EL+ ++      ++   DL K    + E+   + + Q  +   K +   QE
Sbjct: 1251 IDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQE 1303



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 20/72 (27%), Positives = 38/72 (52%)

Query: 121 FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGIL 180
           F F ++F       + +      ++   ++G N  I+ YG T SGKT+T+ G+    G++
Sbjct: 47  FNFDRVFHGNETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVI 106

Query: 181 PRSLALIFNSLQ 192
           PR++  IF  ++
Sbjct: 107 PRAIHDIFQKIK 118



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 65/286 (22%), Positives = 130/286 (45%), Gaps = 37/286 (12%)

Query: 560  KEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLE 619
            K+  LQ +E+ K L L  R ++ Q E+ +       M+++ ++ ++   E L  +++ L+
Sbjct: 1560 KDSALQSIES-KMLELTNRLQESQEEIQI-------MIKEKEEMKR-VQEALQIERDQLK 1610

Query: 620  EMYEEKLNILKESLTSFYQ----EEIQERDEKIEELEALLQEARQQSVAHQQSGSELALR 675
            E  +E +  +KES    YQ      + E  EK+ E+E L ++   Q +  +   +E  +R
Sbjct: 1611 ENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETE-NIR 1669

Query: 676  RSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLE 735
             +Q L      + L+E+++  ++ + +L S  E L   +  L+     +  T D++K   
Sbjct: 1670 LTQILH-----ENLEEMRSVTKE-RDDLRSVEETLKVERDQLKEN-LRETITRDLEK--- 1719

Query: 736  EGQKNIRLLRTELQKLGESLQSAERACCHSTGA-GKLRQALTTCDDILIKQDQTLAELQN 794
              Q+ ++++   L++  E++          T     +++ L   +D L  QD  + E   
Sbjct: 1720 --QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQE--- 1774

Query: 795  NMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPN 840
                   +LR     + EQ  T+ KL+G VS K    +N +    N
Sbjct: 1775 -------ELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLEN 1813



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 54/226 (23%), Positives = 105/226 (46%), Gaps = 18/226 (7%)

Query: 543 TGLDDDIENEADISMYGKEELLQVVEAMKTL------LLKERQEKLQLEMHL----RDEI 592
           T L  ++  E + +   +EE++ + E +K+L      L KE Q+K + E+H+    +D++
Sbjct: 723 TDLQKELNKEVEENEALREEVILLSE-LKSLPSEVERLRKEIQDKSE-ELHIITSEKDKL 780

Query: 593 CNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKE--SLTSFYQEEIQERDEKIEE 650
            +E+V + + R Q   E +   K+ L        +  +E  +  + + +  Q+    +EE
Sbjct: 781 FSEVVHK-ESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEE 839

Query: 651 LEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEEL 710
            E + QE    S   Q+  S L   +++    S  TQ+LQE   ++Q+   E+    E+L
Sbjct: 840 NERMNQEIVNLSKEAQKFDSSLGALKTE---LSYKTQELQEKTREVQERLNEMEQLKEQL 896

Query: 711 HKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQ 756
                 L+     K    +  ++  E  K +   + +L++L ESLQ
Sbjct: 897 ENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQ 942



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 54/237 (22%), Positives = 97/237 (40%), Gaps = 55/237 (23%)

Query: 551  NEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEH 610
            NE    +   E+L + ++     L K   E L L   L + +  EM   M++R+      
Sbjct: 1840 NETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENL-EEMKSVMKERDNL---- 1894

Query: 611  LDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGS 670
                        EE L + ++ L    +E +QE   +  E++  L+ AR  S  H+++  
Sbjct: 1895 ---------RRVEETLKLERDQL----KESLQETKARDLEIQQELKTARMLSKEHKETVD 1941

Query: 671  ELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHK---------------YQK 715
            +L  + S++      T Q+ +++  L + K EL    +EL K               ++K
Sbjct: 1942 KLREKISEK------TIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK 1995

Query: 716  MLEPPPSAKPF-------------TIDVDKKLEEGQKNIRLL---RTELQKLGESLQ 756
            + E     K F                + KKL E  + IR++   R EL+++ ESL+
Sbjct: 1996 INEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLK 2052



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 60/261 (22%), Positives = 114/261 (43%), Gaps = 26/261 (9%)

Query: 586  MHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESL---TSFYQEEIQ 642
            +H+  E   +MV  +++ E+   E ++  KE   + ++  L  LK  L   T   QE+ +
Sbjct: 825  LHMDFEQKYKMV--LEENERMNQEIVNLSKEA--QKFDSSLGALKTELSYKTQELQEKTR 880

Query: 643  ERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAE 702
            E  E++ E+E L ++   +    Q       + R + L      Q L+EVK  L Q K +
Sbjct: 881  EVQERLNEMEQLKEQLENRDSTLQ------TVEREKTLITEKLQQTLEEVKT-LTQEKDD 933

Query: 703  LNSTTEELHKYQKMLEPP-PSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERA 761
            L    E L   +  L+          ID  ++L    ++++  +  +  L   +      
Sbjct: 934  LKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSR 993

Query: 762  CCH---STGAGK--LRQALTTCD---DILIKQDQTL-AELQNNMVLVKLDLRKKAACIAE 812
              H   +TG  K   +Q +   D   D+  K  QTL A++++N ++ +   RK  + I E
Sbjct: 994  NLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQ--QRKIFSLIQE 1051

Query: 813  QYHTVLKLQGQVSAKKRLGTN 833
            +      L+  ++ K++L T+
Sbjct: 1052 KNELQQMLESVIAEKEQLKTD 1072



 Score = 37.0 bits (84), Expect = 0.082
 Identities = 60/292 (20%), Positives = 127/292 (43%), Gaps = 57/292 (19%)

Query: 568  EAMKTLLLKERQE-KLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKL 626
            EA ++ + KE +  K+Q E+    E+ N+++ ++Q +    ++ L+  KE ++ + ++  
Sbjct: 2392 EAKESAMHKESKIIKMQKEL----EVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVA 2447

Query: 627  NILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASAST 686
               K      Y+EEI++   K+ +++  L++ +             A    + ++A+ +T
Sbjct: 2448 LGAKP-----YKEEIEDLKMKLVKID--LEKMKN------------AKEFEKEISATKAT 2488

Query: 687  QQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRT 746
             + Q+   +L +     +   ++     +  +P PS KP T      + +  K + +L++
Sbjct: 2489 VEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKAL-ILKS 2547

Query: 747  ELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVL-------- 798
            E  +L + +              KL+Q     ++ LIKQ   L  L NN  L        
Sbjct: 2548 EHIRLEKEI-------------SKLKQQ----NEQLIKQKNEL--LSNNQHLSNEVKTWK 2588

Query: 799  ---VKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPNQQPPGKK 847
               +K +  K+  C  E      K+ G  S KK++  +Q  ++  Q P  K+
Sbjct: 2589 ERTLKREAHKQVTC--ENSPKSPKVTGTASKKKQITPSQCKERNLQDPVPKE 2638



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 56/278 (20%), Positives = 111/278 (39%), Gaps = 33/278 (11%)

Query: 550  ENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSE 609
            EN  +I    KE   +  + +K   + E QEK+    HL+                   E
Sbjct: 1611 ENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK-------------------E 1651

Query: 610  HLDTQKELLEEMYEEKL---NILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQ 666
              +TQK  LE +  E +    IL E+L    +   +ERD+ +  +E  L+  R Q   + 
Sbjct: 1652 QFETQKLNLENIETENIRLTQILHENLEEM-RSVTKERDD-LRSVEETLKVERDQLKENL 1709

Query: 667  QSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPF 726
            +      L + + L        L+E +  + + +  ++  T E+   QK LE    A   
Sbjct: 1710 RETITRDLEKQEEL--KIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKA 1767

Query: 727  TIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTG-AGKLRQALTTCDDILIKQ 785
                D K++E    +R+    L++  E++          T     +++ L   +  L ++
Sbjct: 1768 Q---DLKIQE---ELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEK 1821

Query: 786  DQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQ 823
             Q L   ++ ++ +K D+ +    ++E      +++ Q
Sbjct: 1822 IQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQ 1859



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 56/259 (21%), Positives = 106/259 (40%), Gaps = 52/259 (20%)

Query: 520  LHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQV---VEAMKTLLLK 576
            +   +K+ S    PS++      T     + N  +++ +  EE L     +E +K  + K
Sbjct: 2239 IEEILKDFSESEFPSIK------TEFQQVLSNRKEMTQF-LEEWLNTRFDIEKLKNGIQK 2291

Query: 577  ERQEKLQLEMHLRDEICNEMVEQMQQRE-------QWCSEHLDTQKELLEEMYEEKLNIL 629
            E     Q+     + I   M E  +  E       +W  + L + KE  E++++     L
Sbjct: 2292 ENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEW-EQDLKSLKEKNEKLFKN-YQTL 2349

Query: 630  KESLTSFYQEEIQERD---------------EKIEELEALLQEARQQSVAHQQSGSELAL 674
            K SL S  Q     +D               EKI ELE  L EA+ +S  H++       
Sbjct: 2350 KTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAK-ESAMHKE------- 2401

Query: 675  RRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPS--AKPFTIDVDK 732
              S+ +      +   ++ AKLQ    E N   E+  +  ++L+   +  AKP+  +++ 
Sbjct: 2402 --SKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIE- 2458

Query: 733  KLEEGQKNIRLLRTELQKL 751
                    ++L++ +L+K+
Sbjct: 2459 -----DLKMKLVKIDLEKM 2472


>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
          Length = 1153

 Score =  132 bits (332), Expect = 1e-30
 Identities = 77/213 (36%), Positives = 124/213 (58%), Gaps = 8/213 (3%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           +S+ +S+ EIY E + DLL P    + +  LR+ E     PYV+DL+ + V    +   L
Sbjct: 140 YSVEVSYMEIYCERVRDLLNP----KNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADL 195

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDI---VPKISELSLCDLAGSERC 415
           +  G K ++ A+T++N+ SSRSH++F+I     + + +      K+S++SL DLAGSER 
Sbjct: 196 MDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSKISLVDLAGSERA 255

Query: 416 KDQKS-GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
               + G RLKE  NIN SL TLG+ I+AL +  + + K + +P+RDS LT + +    G
Sbjct: 256 DSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGG 315

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQL 507
             R+ M+  ++P    YDETL   +++  A Q+
Sbjct: 316 NSRTAMVAALSPADINYDETLSTLRYADRAKQI 348



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 6/129 (4%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           VKV +RVRP    E  + E +  ++++   T ++       A KS        +H     
Sbjct: 6   VKVAVRVRPFNSRETSK-ESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPED 64

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKD--GGILPR 182
             F     Q   +N   KEM+    +G N  I+ YG T +GK++T+ G  ++   GI+P+
Sbjct: 65  PCFA---SQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQ 121

Query: 183 SLALIFNSL 191
               +F  +
Sbjct: 122 LCEELFEKI 130


>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
          Length = 1770

 Score =  132 bits (332), Expect = 1e-30
 Identities = 77/213 (36%), Positives = 124/213 (58%), Gaps = 8/213 (3%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           +S+ +S+ EIY E + DLL P    + +  LR+ E     PYV+DL+ + V    +   L
Sbjct: 140 YSVEVSYMEIYCERVRDLLNP----KNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADL 195

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDI---VPKISELSLCDLAGSERC 415
           +  G K ++ A+T++N+ SSRSH++F+I     + + +      K+S++SL DLAGSER 
Sbjct: 196 MDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSKISLVDLAGSERA 255

Query: 416 KDQKS-GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTG 474
               + G RLKE  NIN SL TLG+ I+AL +  + + K + +P+RDS LT + +    G
Sbjct: 256 DSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGG 315

Query: 475 RGRSCMIVNVNPCASTYDETLHVAKFSAIASQL 507
             R+ M+  ++P    YDETL   +++  A Q+
Sbjct: 316 NSRTAMVAALSPADINYDETLSTLRYADRAKQI 348



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 6/129 (4%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           VKV +RVRP    E  + E +  ++++   T ++       A KS        +H     
Sbjct: 6   VKVAVRVRPFNSRETSK-ESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPED 64

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKD--GGILPR 182
             F     Q   +N   KEM+    +G N  I+ YG T +GK++T+ G  ++   GI+P+
Sbjct: 65  PCFA---SQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQ 121

Query: 183 SLALIFNSL 191
               +F  +
Sbjct: 122 LCEELFEKI 130


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score =  131 bits (330), Expect = 2e-30
 Identities = 152/570 (26%), Positives = 251/570 (44%), Gaps = 63/570 (11%)

Query: 296 NIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           N+ F I +S+FEIY + + DLL+       +  L + ED+N  P+VK      V   EE 
Sbjct: 126 NLEFHIKVSYFEIYLDKIRDLLDVT-----KTNLSVHEDKNRVPFVKGCTERFVSSPEEI 180

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKIS-ELSLCDLAGSER 414
             ++  G+ N+  A T++N++SSRSHSIF I I   Q   +   K+S +L L DLAGSE+
Sbjct: 181 LDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINI--KQENMETEQKLSGKLYLVDLAGSEK 238

Query: 415 -CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFT 473
             K    G  L EA NIN SL  LG  I+AL +       ++ VP+RDSK+TR+ Q    
Sbjct: 239 VSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GTKSYVPYRDSKMTRILQDSLG 293

Query: 474 GRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPS---LHSFIKEHSLQ 530
           G  R+ M +  +P +    ET     F   A  + +   + L   +      + KE   +
Sbjct: 294 GNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKE-K 352

Query: 531 VSPSLEKGAKADTGLD--DDIENEADISMYGKEELLQVVEAMKTLLLKER---------Q 579
                E  AK +  L    + EN  +      EE     E  +   + +          +
Sbjct: 353 TKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPE 412

Query: 580 EKLQLEMHLR------DEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESL 633
           E+ + E  +R      D+  +E+ +Q Q  E+   + LD Q+ELL     +   + +E L
Sbjct: 413 ERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLD-QEELLVSTRGDNEKVQRE-L 470

Query: 634 TSFYQEEIQERDEKIEELEAL----------LQEARQQSVAHQQSGSELALRRSQRLAAS 683
           +    E    +DE  E L+AL           QE  ++S  +Q    EL+ + +  L+  
Sbjct: 471 SHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLE 530

Query: 684 ASTQQLQEVKAKLQQCKAE-LNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIR 742
           +  Q+LQEV    ++  AE LN   ++L ++  ++       P  +++   +EE      
Sbjct: 531 SELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLP--VEISGAIEE---EFT 585

Query: 743 LLRTELQKLGESLQSAERAC---------CHSTGAGKLRQALTTCDDILIKQDQTLAELQ 793
           + R  + K+   ++S  + C         CH       R+ L++C  ++ + +  +  L 
Sbjct: 586 VARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRE-LSSCQLLISQHEAKIRSLT 644

Query: 794 NNMVLVKLDLRKKAACIAEQYHTVLKLQGQ 823
             M  V+L  R            + KLQ Q
Sbjct: 645 EYMQSVELKKRHLEESYDSLSDELAKLQAQ 674



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 30/74 (40%), Positives = 44/74 (59%), Gaps = 3/74 (4%)

Query: 121 FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDG--- 177
           + F ++F P   Q   ++    ++VKDVL G N  I+ YG T+SGKTHT++G + D    
Sbjct: 47  YVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106

Query: 178 GILPRSLALIFNSL 191
           GI+PR    IFN +
Sbjct: 107 GIIPRIARDIFNHI 120


>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
          Length = 1690

 Score =  129 bits (324), Expect = 1e-29
 Identities = 78/222 (35%), Positives = 125/222 (56%), Gaps = 14/222 (6%)

Query: 296 NIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           N+ +S+ +S+ EIY E + DLL P    + +  LR+ E     PYV+DL+ + V    + 
Sbjct: 137 NMSYSVEVSYMEIYCERVRDLLNP----KNKGNLRVREHPLLGPYVEDLSKLAVTSYNDI 192

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGD---IVPKISELSLCDLAGS 412
             L+  G K ++ A+T++N+ SSRSH++F+I     + + +      K+S++SL DLAGS
Sbjct: 193 QDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGS 252

Query: 413 ERCKDQ-KSGERLKEAGNINTSLHTLGRCIAALRQ------NQQNRSKQNLVPFRDSKLT 465
           ER       G RLKE  NIN SL TLG+ I+AL +        + + K + +P+RDS LT
Sbjct: 253 ERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLT 312

Query: 466 RVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQL 507
            + +    G  R+ M+  ++P    YDETL   +++  A Q+
Sbjct: 313 WLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 354



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 14/133 (10%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           VKV +RVRP    E+ R  D  C+   +  T  +  PK     K   +     +  +++ 
Sbjct: 6   VKVAVRVRPFNSREMSR--DSKCIIQMSGSTTTIVNPKQP---KETPKSF---SFDYSYW 57

Query: 125 QIFGPE----VGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIK--DGG 178
               PE      Q   +    +EM++   +G N  I+ YG T +GK++T+ G  +    G
Sbjct: 58  SHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQG 117

Query: 179 ILPRSLALIFNSL 191
           I+P+    +F+ +
Sbjct: 118 IIPQLCEDLFSRI 130


>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
          Length = 1028

 Score =  128 bits (322), Expect = 2e-29
 Identities = 131/482 (27%), Positives = 211/482 (43%), Gaps = 67/482 (13%)

Query: 296 NIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           N +F +  S+ EIYNE + DLL   ++Q+    L L E      YVK L+   V    + 
Sbjct: 130 NTKFLVRASYLEIYNEDVRDLLGADTKQK----LELKEHPEKGVYVKGLSMHTVHSVAQC 185

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIF--SIRILHLQGEGDIVPKISELSLCDLAGSE 413
             +++ G KN+S   T +N++SSRSHSIF  SI +  +   G    +  +L+L DLAGSE
Sbjct: 186 EHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGSE 245

Query: 414 R-CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFF 472
           R  K   +GERLKEA  IN SL  LG  I+AL      R K   VP+RDSKLTR+ Q   
Sbjct: 246 RQSKTGATGERLKEATKINLSLSALGNVISAL---VDGRCKH--VPYRDSKLTRLLQDSL 300

Query: 473 TGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVS 532
            G  ++ M+  ++P  + YDETL   +++  A  + + P +                   
Sbjct: 301 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN------------------ 342

Query: 533 PSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEI 592
                            E+  D  +   +E ++ ++A+ T  +        L   +  + 
Sbjct: 343 -----------------EDPKDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPD- 384

Query: 593 CNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELE 652
               VE+    +      ++ +K+L+ E YEE+L  LK      Y+ E + R    E++ 
Sbjct: 385 -PVQVEEKLLPQPVIQHDVEAEKQLIREEYEERLARLKAD----YKAEQESRARLEEDIT 439

Query: 653 ALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTE--EL 710
           A+     + S   + S  E  LR+              EV +     +AE  S+ E    
Sbjct: 440 AM-----RNSYDVRLSTLEENLRKETEAVLQVGVLYKAEVMS-----RAEFASSAEYPPA 489

Query: 711 HKYQKMLEPPPSAKPFTIDVD--KKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGA 768
            +Y+ +++P   +   T+  D   K +   +   L + E  K   SL S+E +    T  
Sbjct: 490 FQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSV 549

Query: 769 GK 770
            +
Sbjct: 550 SE 551



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 13/133 (9%)

Query: 63  EKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFT 122
           E VKV +R RP+     +R+ +  C  +  V+    Q          N     +   +FT
Sbjct: 4   EAVKVVVRCRPMN----QRERELRCQPVVTVDCARAQC------CIQNPGAADEPPKQFT 53

Query: 123 FSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQG---TIKDGGI 179
           F   +  +      +N     +V+ V +G N  I+ YG T SGK+ T+QG        GI
Sbjct: 54  FDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGI 113

Query: 180 LPRSLALIFNSLQ 192
           +PR+   +F S+Q
Sbjct: 114 IPRAFEHVFESVQ 126


>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
          Length = 1029

 Score =  128 bits (322), Expect = 2e-29
 Identities = 131/482 (27%), Positives = 211/482 (43%), Gaps = 67/482 (13%)

Query: 296 NIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           N +F +  S+ EIYNE + DLL   ++Q+    L L E      YVK L+   V    + 
Sbjct: 130 NTKFLVRASYLEIYNEDVRDLLGADTKQK----LELKEHPEKGVYVKGLSMHTVHSVAQC 185

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIF--SIRILHLQGEGDIVPKISELSLCDLAGSE 413
             +++ G KN+S   T +N++SSRSHSIF  SI +  +   G    +  +L+L DLAGSE
Sbjct: 186 EHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGSE 245

Query: 414 R-CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFF 472
           R  K   +GERLKEA  IN SL  LG  I+AL      R K   VP+RDSKLTR+ Q   
Sbjct: 246 RQSKTGATGERLKEATKINLSLSALGNVISAL---VDGRCKH--VPYRDSKLTRLLQDSL 300

Query: 473 TGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVS 532
            G  ++ M+  ++P  + YDETL   +++  A  + + P +                   
Sbjct: 301 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN------------------ 342

Query: 533 PSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEI 592
                            E+  D  +   +E ++ ++A+ T  +        L   +  + 
Sbjct: 343 -----------------EDPKDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPD- 384

Query: 593 CNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELE 652
               VE+    +      ++ +K+L+ E YEE+L  LK      Y+ E + R    E++ 
Sbjct: 385 -PVQVEEKLLPQPVIQHDVEAEKQLIREEYEERLARLKAD----YKAEQESRARLEEDIT 439

Query: 653 ALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTE--EL 710
           A+     + S   + S  E  LR+              EV +     +AE  S+ E    
Sbjct: 440 AM-----RNSYDVRLSTLEENLRKETEAVLQVGVLYKAEVMS-----RAEFASSAEYPPA 489

Query: 711 HKYQKMLEPPPSAKPFTIDVD--KKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGA 768
            +Y+ +++P   +   T+  D   K +   +   L + E  K   SL S+E +    T  
Sbjct: 490 FQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSV 549

Query: 769 GK 770
            +
Sbjct: 550 SE 551



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 13/133 (9%)

Query: 63  EKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFT 122
           E VKV +R RP+     +R+ +  C  +  V+    Q          N     +   +FT
Sbjct: 4   EAVKVVVRCRPMN----QRERELRCQPVVTVDCARAQC------CIQNPGAADEPPKQFT 53

Query: 123 FSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQG---TIKDGGI 179
           F   +  +      +N     +V+ V +G N  I+ YG T SGK+ T+QG        GI
Sbjct: 54  FDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGI 113

Query: 180 LPRSLALIFNSLQ 192
           +PR+   +F S+Q
Sbjct: 114 IPRAFEHVFESVQ 126


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score =  128 bits (322), Expect = 2e-29
 Identities = 123/491 (25%), Positives = 221/491 (45%), Gaps = 77/491 (15%)

Query: 296 NIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           N ++ +  S+ EIY E + DLL     +R    L L E+     Y+KDL+    ++ +E 
Sbjct: 136 NQQYLVRASYLEIYQEEIRDLLSKEPGKR----LELKENPETGVYIKDLSSFVTKNVKEI 191

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQ--GEGDIVPKISELSLCDLAGSE 413
             ++ +G + ++  STH+N+ SSRSH+IF I +   +   +G    ++ +L+L DLAGSE
Sbjct: 192 EHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVDLAGSE 251

Query: 414 RCKDQ-------------------------KSGERLKEAGNINTSLHTLGRCIAALRQNQ 448
           R                               GER KEA  IN SL  LG  IAAL  N+
Sbjct: 252 RQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALAGNR 311

Query: 449 QNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLV 508
                   +P+RDSKLTR+ Q    G  ++ M+  + P + +YDE+L   +F+  A  + 
Sbjct: 312 STH-----IPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIK 366

Query: 509 HAPPM---------------------------QLG-FPSLHSFIKEHSLQVSPSLEKGAK 540
           + P +                            LG  P   S  ++ ++   P   +G  
Sbjct: 367 NKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPV 426

Query: 541 ADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHL----RDEICNEM 596
            +  + ++ ++  +     +  L   +E      L+E++E+L+ E       R  +  E 
Sbjct: 427 IEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEK 486

Query: 597 VEQMQQREQWCSEHLDTQK--ELLEEMY---EEKLNILKESL---TSFYQEEIQERDEKI 648
            + ++++E+   +    Q+  ELL   Y   E KL I   ++   T+  Q+ ++ + ++I
Sbjct: 487 QKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEI 546

Query: 649 EELEALLQEARQQSVAHQQSGSEL-ALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTT 707
            E +   +E +Q+ +   +   EL     S +      T++L+++ AKLQ  KAE+    
Sbjct: 547 AEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQH 606

Query: 708 EELHKYQKMLE 718
           +E  + ++ LE
Sbjct: 607 DEYIRVRQDLE 617



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 54/226 (23%), Positives = 97/226 (42%), Gaps = 25/226 (11%)

Query: 63  EKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFT 122
           E +KV  R RPL   E     +Q          L +        L++     G+    FT
Sbjct: 9   EALKVVARCRPLSRKEEAAGHEQ---------ILTMDVKLGQVTLRNPRAAPGELPKTFT 59

Query: 123 FSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKD---GGI 179
           F  ++     QA  ++ TV+ ++  VL+G N  ++ YG T +GKT+T+QGT  +    G+
Sbjct: 60  FDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGV 119

Query: 180 LPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELST 239
           +P +   IF  +    +            ++     +I QEE++ L     G +  EL  
Sbjct: 120 IPNAFEHIFTHISRSQN---------QQYLVRASYLEIYQEEIRDLLSKEPG-KRLELKE 169

Query: 240 SLKRSVYIE---SRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHR 282
           + +  VYI+   S +  +      +  L + ++   S+ ++E S R
Sbjct: 170 NPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSR 215


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score =  127 bits (320), Expect = 4e-29
 Identities = 109/351 (31%), Positives = 163/351 (46%), Gaps = 57/351 (16%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           F   +S+ EIYNE + DLL   S   K   LR+ E     PYV+DL+   VQ+  +  +L
Sbjct: 144 FRTEVSYLEIYNERVRDLLRRKSS--KTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEEL 201

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDI-VPKISELSLCDLAGSERC-K 416
           +  G  N++ A+T +N  SSRSH+IF+I+    + + ++    +S++ L DLAGSER   
Sbjct: 202 MDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPCETVSKIHLVDLAGSERADA 261

Query: 417 DQKSGERLKEAGNINTSLHTLGRCIAALRQNQQN------RSKQNLVPFRDSKLTRVFQG 470
              +G RLKE GNIN SL TLG  I+AL    Q+      + KQ  VP+RDS LT + + 
Sbjct: 262 TGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKD 321

Query: 471 FFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQ 530
              G  ++ MI  ++P    Y ETL   +++  A  +++ P                   
Sbjct: 322 SLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKP------------------- 362

Query: 531 VSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRD 590
                             I  +A++ +    EL   +  +KTLL +  Q  L     L  
Sbjct: 363 -----------------TINEDANVKLI--RELRAEIARLKTLLAQGNQIAL-----LDS 398

Query: 591 EICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEI 641
                M E++QQ E    E     KE   + + E  NILKE   +  +E I
Sbjct: 399 PTALSMEEKLQQNEARVQE---LTKEWTNK-WNETQNILKEQTLALRKEGI 445



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 42/141 (29%), Positives = 67/141 (47%), Gaps = 19/141 (13%)

Query: 62  MEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQA---- 117
           M  VKV +RVRP+   E +  E +  +++E  +T +         LK  E G G +    
Sbjct: 1   MASVKVAVRVRPMNRREKDL-EAKFIIQMEKSKTTITN-------LKIPEGGTGDSGRER 52

Query: 118 THRFTFSQIF------GPE-VGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTI 170
           T  FT+   F       P+ V Q   F     ++VK   +G N  ++ YG T SGK++T+
Sbjct: 53  TKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTM 112

Query: 171 QGTIKDGGILPRSLALIFNSL 191
            G   D G++PR    +F+ +
Sbjct: 113 MGNSGDSGLIPRICEGLFSRI 133



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 43/185 (23%), Positives = 86/185 (46%), Gaps = 27/185 (14%)

Query: 577 ERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSF 636
           ERQ++ +LE   + E   +++E+M+++++       + K  LE M +E     KE  T  
Sbjct: 599 ERQQREELE---KLESKRKLIEEMEEKQK-------SDKAELERMQQEVETQRKE--TEI 646

Query: 637 YQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQ-------- 688
            Q +I++++E ++     ++   +  +A ++   E  LR  Q +      Q+        
Sbjct: 647 VQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQ 706

Query: 689 --LQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKK-LEEGQKNIRLLR 745
             LQ +K      KAE     +EL + QK  +   +     ++++KK LEE +K   +L 
Sbjct: 707 EELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYA----KLELEKKRLEEQEKEQVMLV 762

Query: 746 TELQK 750
             L++
Sbjct: 763 AHLEE 767



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 50/223 (22%), Positives = 99/223 (44%), Gaps = 39/223 (17%)

Query: 558  YGKEELLQVVEAMKTLLLKERQEKLQL----EMHLRDEICNEMVEQMQQREQWCSEHLDT 613
            Y + +L  +++     LL+E+Q   ++     + L D    ++ ++M+++E+  ++    
Sbjct: 904  YKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSL-DNTLYQVEKEMEEKEEQLAQ---- 958

Query: 614  QKELLEEMYEEKLNILKESLTSF-YQEEIQERDEKIEELEALLQEAR--QQSVAHQQSGS 670
                    Y+   N L++   +F +   I  ++EK+ + E  + E+R  QQ  A +++ +
Sbjct: 959  --------YQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALA 1010

Query: 671  ELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDV 730
             L  R S     S    +++E + KL    A LNS + E    Q  LE    A       
Sbjct: 1011 RLERRHSALQRHSTLGMEIEEQRQKL----ASLNSGSREQSGLQASLEAEQEA------- 1059

Query: 731  DKKLEEGQKNIRLLRTELQKLGESLQSAE--RACCHSTGAGKL 771
               LE+ Q+    L  E+Q+L + +   +  +   H T  GK+
Sbjct: 1060 ---LEKDQER---LEYEIQQLKQKIYEVDGVQKDHHGTLEGKV 1096



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 72/309 (23%), Positives = 127/309 (41%), Gaps = 31/309 (10%)

Query: 526 EHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLE 585
           +  LQ    L    KA+      I  E D     K+E    +E  K  L ++ +E++ L 
Sbjct: 706 QEELQRLKELNNNEKAEKF---QIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLV 762

Query: 586 MHLRDEI--CNEMVEQMQQRE-QWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQ 642
            HL +++    EM++ +++ E QW  E    +K  LE + E  L +         +E   
Sbjct: 763 AHLEEQLREKQEMIQLLRRGEVQWVEE----EKRDLEGIRESLLRV---------KEARA 809

Query: 643 ERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAE 702
             DE  EELE    + R      +Q    + L +          +++QE +  L+  K E
Sbjct: 810 GGDEDGEELEK--AQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCE 867

Query: 703 LNSTTEELHKYQK----MLEPPPSAKPFTIDVDKKLEEGQKNIR-LLRTELQKLGESLQS 757
            +  +  L K+ +    + E P   +     V+ +L+  ++ ++ LL+  L  L E  Q 
Sbjct: 868 HDKESRLLEKHDESVTDVTEVPQDFEKIK-PVEYRLQYKERQLQYLLQNHLPTLLEEKQR 926

Query: 758 AERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNM-VLVKLDLR-KKAACIAEQYH 815
           A        G   L   L   +  + ++++ LA+ Q N   L KL    +  A IA Q  
Sbjct: 927 AFEIL--DRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEE 984

Query: 816 TVLKLQGQV 824
            V K + ++
Sbjct: 985 KVRKKEKEI 993


>gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]
          Length = 826

 Score =  126 bits (316), Expect = 1e-28
 Identities = 85/239 (35%), Positives = 130/239 (54%), Gaps = 12/239 (5%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           ++I +S  EIYNE+L DLL    Q++    +RLC D +G  YV  L    VQ  ++  K+
Sbjct: 568 YTITVSAAEIYNEVLRDLLGKEPQEKLE--IRLCPDGSGQLYVPGLTEFQVQSVDDINKV 625

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERC-KD 417
            + G  N++   T+LN++SSRSH++  + +  +     +     +L+L DLAGSER  K 
Sbjct: 626 FEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGL-RTTGKLNLVDLAGSERVGKS 684

Query: 418 QKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGR 477
              G RL+EA +IN SL  LG  IAAL      RS+Q  VPFR+SKLT + Q   +G  +
Sbjct: 685 GAEGSRLREAQHINKSLSALGDVIAAL------RSRQGHVPFRNSKLTYLLQDSLSGDSK 738

Query: 478 SCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLE 536
           + M+V V+P      ETL+  KF+     +   P ++     L S+  +  L+  P+ +
Sbjct: 739 TLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRA--ELGSWSSQEHLEWEPACQ 795



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 13/128 (10%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           ++V  RVRP+   + E  E    V  +  +  ++        +             F   
Sbjct: 446 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVS------------FELD 493

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSL 184
           ++F P+  Q   F   V+ +V   + G N  I+ YG T +GKT+T++GT ++ GI  R+L
Sbjct: 494 KVFSPQASQQDVFQ-EVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRAL 552

Query: 185 ALIFNSLQ 192
            L+F+ +Q
Sbjct: 553 QLLFSEVQ 560



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 43/245 (17%), Positives = 101/245 (41%), Gaps = 40/245 (16%)

Query: 513 MQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKT 572
           +QL        + E +L+V    ++ A+ +  L D +  +A         L    E + +
Sbjct: 187 LQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIAS 246

Query: 573 LLLKERQEKLQLE-MHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEE-----KL 626
           L  +    K  ++ + +      + + + Q R Q   E +  Q+++L+EM ++     +L
Sbjct: 247 LRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQL 306

Query: 627 NILKESLTSFYQEEIQE-RDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASAS 685
                +  + Y+ E++    + +EE+++L +E + +++    + +++ ++      A   
Sbjct: 307 TARLRAQIAMYESELERAHGQMLEEMQSL-EEDKNRAIEEAFARAQVEMKAVHENLAGVR 365

Query: 686 T-------------------------------QQLQEVKAKLQQCKAELNSTTEE-LHKY 713
           T                               + L+ VKA++ Q   E+NS  +E L KY
Sbjct: 366 TNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKY 425

Query: 714 QKMLE 718
           ++ L+
Sbjct: 426 RRELQ 430



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 16/140 (11%)

Query: 575 LKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLT 634
           L+++  +LQLEM     + +E+  ++QQ+    +E     K+ L E  +E+  +      
Sbjct: 180 LRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERL------ 233

Query: 635 SFYQEEIQERDEKIEELEALLQEARQ--QSVAHQQSGSELALRRSQRLAASASTQQLQEV 692
                 +++  E I  L A     +   ++V  + S ++ AL  SQ     A  Q LQE 
Sbjct: 234 ---SRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQ-----ARNQHLQEQ 285

Query: 693 KAKLQQCKAELNSTTEELHK 712
            A  +Q   E+    +  H+
Sbjct: 286 VAMQRQVLKEMEQQLQSSHQ 305


>gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]
          Length = 687

 Score =  126 bits (316), Expect = 1e-28
 Identities = 85/239 (35%), Positives = 130/239 (54%), Gaps = 12/239 (5%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           ++I +S  EIYNE+L DLL    Q++    +RLC D +G  YV  L    VQ  ++  K+
Sbjct: 429 YTITVSAAEIYNEVLRDLLGKEPQEKLE--IRLCPDGSGQLYVPGLTEFQVQSVDDINKV 486

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERC-KD 417
            + G  N++   T+LN++SSRSH++  + +  +     +     +L+L DLAGSER  K 
Sbjct: 487 FEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGL-RTTGKLNLVDLAGSERVGKS 545

Query: 418 QKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGR 477
              G RL+EA +IN SL  LG  IAAL      RS+Q  VPFR+SKLT + Q   +G  +
Sbjct: 546 GAEGSRLREAQHINKSLSALGDVIAAL------RSRQGHVPFRNSKLTYLLQDSLSGDSK 599

Query: 478 SCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLE 536
           + M+V V+P      ETL+  KF+     +   P ++     L S+  +  L+  P+ +
Sbjct: 600 TLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRA--ELGSWSSQEHLEWEPACQ 656



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 13/128 (10%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           ++V  RVRP+   + E  E    V  +  +  ++        +             F   
Sbjct: 307 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVS------------FELD 354

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSL 184
           ++F P+  Q   F   V+ +V   + G N  I+ YG T +GKT+T++GT ++ GI  R+L
Sbjct: 355 KVFSPQASQQDVFQ-EVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRAL 413

Query: 185 ALIFNSLQ 192
            L+F+ +Q
Sbjct: 414 QLLFSEVQ 421



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 43/245 (17%), Positives = 101/245 (41%), Gaps = 40/245 (16%)

Query: 513 MQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKT 572
           +QL        + E +L+V    ++ A+ +  L D +  +A         L    E + +
Sbjct: 48  LQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIAS 107

Query: 573 LLLKERQEKLQLE-MHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEE-----KL 626
           L  +    K  ++ + +      + + + Q R Q   E +  Q+++L+EM ++     +L
Sbjct: 108 LRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQL 167

Query: 627 NILKESLTSFYQEEIQE-RDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASAS 685
                +  + Y+ E++    + +EE+++L +E + +++    + +++ ++      A   
Sbjct: 168 TARLRAQIAMYESELERAHGQMLEEMQSL-EEDKNRAIEEAFARAQVEMKAVHENLAGVR 226

Query: 686 T-------------------------------QQLQEVKAKLQQCKAELNSTTEE-LHKY 713
           T                               + L+ VKA++ Q   E+NS  +E L KY
Sbjct: 227 TNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKY 286

Query: 714 QKMLE 718
           ++ L+
Sbjct: 287 RRELQ 291



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 16/140 (11%)

Query: 575 LKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLT 634
           L+++  +LQLEM     + +E+  ++QQ+    +E     K+ L E  +E+  +      
Sbjct: 41  LRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERL------ 94

Query: 635 SFYQEEIQERDEKIEELEALLQEARQ--QSVAHQQSGSELALRRSQRLAASASTQQLQEV 692
                 +++  E I  L A     +   ++V  + S ++ AL  SQ     A  Q LQE 
Sbjct: 95  ---SRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQ-----ARNQHLQEQ 146

Query: 693 KAKLQQCKAELNSTTEELHK 712
            A  +Q   E+    +  H+
Sbjct: 147 VAMQRQVLKEMEQQLQSSHQ 166


>gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]
          Length = 833

 Score =  126 bits (316), Expect = 1e-28
 Identities = 85/239 (35%), Positives = 130/239 (54%), Gaps = 12/239 (5%)

Query: 299 FSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKL 358
           ++I +S  EIYNE+L DLL    Q++    +RLC D +G  YV  L    VQ  ++  K+
Sbjct: 568 YTITVSAAEIYNEVLRDLLGKEPQEKLE--IRLCPDGSGQLYVPGLTEFQVQSVDDINKV 625

Query: 359 LKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERC-KD 417
            + G  N++   T+LN++SSRSH++  + +  +     +     +L+L DLAGSER  K 
Sbjct: 626 FEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGL-RTTGKLNLVDLAGSERVGKS 684

Query: 418 QKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGR 477
              G RL+EA +IN SL  LG  IAAL      RS+Q  VPFR+SKLT + Q   +G  +
Sbjct: 685 GAEGSRLREAQHINKSLSALGDVIAAL------RSRQGHVPFRNSKLTYLLQDSLSGDSK 738

Query: 478 SCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLE 536
           + M+V V+P      ETL+  KF+     +   P ++     L S+  +  L+  P+ +
Sbjct: 739 TLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRA--ELGSWSSQEHLEWEPACQ 795



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 13/128 (10%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           ++V  RVRP+   + E  E    V  +  +  ++        +             F   
Sbjct: 446 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVS------------FELD 493

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSL 184
           ++F P+  Q   F   V+ +V   + G N  I+ YG T +GKT+T++GT ++ GI  R+L
Sbjct: 494 KVFSPQASQQDVFQ-EVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRAL 552

Query: 185 ALIFNSLQ 192
            L+F+ +Q
Sbjct: 553 QLLFSEVQ 560



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 43/245 (17%), Positives = 101/245 (41%), Gaps = 40/245 (16%)

Query: 513 MQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKT 572
           +QL        + E +L+V    ++ A+ +  L D +  +A         L    E + +
Sbjct: 187 LQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIAS 246

Query: 573 LLLKERQEKLQLE-MHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEE-----KL 626
           L  +    K  ++ + +      + + + Q R Q   E +  Q+++L+EM ++     +L
Sbjct: 247 LRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQL 306

Query: 627 NILKESLTSFYQEEIQE-RDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASAS 685
                +  + Y+ E++    + +EE+++L +E + +++    + +++ ++      A   
Sbjct: 307 TARLRAQIAMYESELERAHGQMLEEMQSL-EEDKNRAIEEAFARAQVEMKAVHENLAGVR 365

Query: 686 T-------------------------------QQLQEVKAKLQQCKAELNSTTEE-LHKY 713
           T                               + L+ VKA++ Q   E+NS  +E L KY
Sbjct: 366 TNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKY 425

Query: 714 QKMLE 718
           ++ L+
Sbjct: 426 RRELQ 430



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 16/140 (11%)

Query: 575 LKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLT 634
           L+++  +LQLEM     + +E+  ++QQ+    +E     K+ L E  +E+  +      
Sbjct: 180 LRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERL------ 233

Query: 635 SFYQEEIQERDEKIEELEALLQEARQ--QSVAHQQSGSELALRRSQRLAASASTQQLQEV 692
                 +++  E I  L A     +   ++V  + S ++ AL  SQ     A  Q LQE 
Sbjct: 234 ---SRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQ-----ARNQHLQEQ 285

Query: 693 KAKLQQCKAELNSTTEELHK 712
            A  +Q   E+    +  H+
Sbjct: 286 VAMQRQVLKEMEQQLQSSHQ 305


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score =  125 bits (314), Expect = 2e-28
 Identities = 151/575 (26%), Positives = 256/575 (44%), Gaps = 73/575 (12%)

Query: 296 NIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           N+ F I +S+FEIY + + DLL+       +  L + ED+N  PYVK      V   EE 
Sbjct: 126 NLEFHIKVSYFEIYLDKIRDLLDV-----SKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKIS-ELSLCDLAGSER 414
             ++  G+ N+  A T++N++SSRSHSIF I I   Q   +   K+S +L L DLAGSE+
Sbjct: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINI--KQENVETEKKLSGKLYLVDLAGSEK 238

Query: 415 -CKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFT 473
             K    G  L EA NIN SL  LG  I+AL +  +       VP+RDSK+TR+ Q    
Sbjct: 239 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTH-----VPYRDSKMTRILQDSLG 293

Query: 474 GRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGF---------------- 517
           G  R+ +++  +P      ET     F   A  + +   + L                  
Sbjct: 294 GNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKN 353

Query: 518 PSLHSFIKEHSLQVS--------PSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEA 569
            +L + I+   ++++        P  E+ +  D    +  +N   I     + +  VV  
Sbjct: 354 KTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPII-----DNIAPVVAG 408

Query: 570 MKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELL-------EEMY 622
           + T   ++  E++       D+  +E+ +Q Q  E+   + LD Q ELL       E++ 
Sbjct: 409 ISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLD-QDELLASTRRDYEKIQ 467

Query: 623 EE--KLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRL 680
           EE  +L I  E+     +E +Q  +E     +   QE   ++ A++Q   ELA + +   
Sbjct: 468 EELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLT 527

Query: 681 AASASTQQLQEVKAKLQQCKAE-LNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQK 739
                  QLQE+    ++   E LN   ++L +   ++    +      DV+  +EE   
Sbjct: 528 TTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGII--GTNDVKTLADVNGVIEEEFT 585

Query: 740 NIRL----LRTELQKL---GESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQ----T 788
             RL    +++E++ L    + L+SA+        A +  + L  C  +LI Q +    +
Sbjct: 586 MARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASE--RELAAC-QLLISQHEAKIKS 642

Query: 789 LAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQ 823
           L +   NM   +  L +    ++E+   + KL+ Q
Sbjct: 643 LTDYMQNMEQKRRQLEESQDSLSEE---LAKLRAQ 674



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 21/130 (16%)

Query: 65  VKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFS 124
           +KV  R RPL  +E+ R  D+   + +  ET+V+   K                  + F 
Sbjct: 9   IKVMCRFRPLNEAEILRG-DKFIPKFKGDETVVIGQGKP-----------------YVFD 50

Query: 125 QIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDG---GILP 181
           ++  P   Q   +N   K++VKDVL+G N  I+ YG T+SGKTHT++G + D    GI+P
Sbjct: 51  RVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110

Query: 182 RSLALIFNSL 191
           R    IF+ +
Sbjct: 111 RIAHDIFDHI 120


>gi|7661878 kinesin family member 14 [Homo sapiens]
          Length = 1648

 Score =  125 bits (313), Expect = 2e-28
 Identities = 78/220 (35%), Positives = 127/220 (57%), Gaps = 9/220 (4%)

Query: 297 IRFSIWISFFEIYNELLYDLLEPPSQQ-RKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEA 355
           + + I +SFFE+YNE ++DLL    +  +++Q LR+ E     PYV+ L+   V    + 
Sbjct: 486 VSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVSSYADI 545

Query: 356 WKLLKVGRKNQSFASTHLNQNSSRSHSIFSI-----RILHLQGEGDIVPKISELSLCDLA 410
              L++G K ++ A+T +N  SSRSHS+F++     +   ++GE       S ++L DLA
Sbjct: 546 QSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRINLIDLA 605

Query: 411 GSERCKD-QKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQ 469
           GSERC     +G+RLKE  +IN SL TLG+ I+AL +    RS    +P+R+S LT + +
Sbjct: 606 GSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSV--FIPYRESVLTWLLK 663

Query: 470 GFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVH 509
               G  ++ MI  ++P AS  +ETL   +++  A  +V+
Sbjct: 664 ESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVN 703



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 48/204 (23%), Positives = 90/204 (44%), Gaps = 14/204 (6%)

Query: 488  ASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDD 547
            A TY    H+ + + +     H   + LG    H F   H ++V    +KG K  +G D 
Sbjct: 867  AKTYVNGKHILEITVLR----HGDRVILGGD--HYFRFNHPVEV----QKG-KRPSGRDT 915

Query: 548  DIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQ--MQQREQ 605
             I        + K ELL    +     +KE Q K + EM    +I  EM +Q    Q+  
Sbjct: 916  PISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAA 975

Query: 606  WCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIE-ELEALLQEARQQSVA 664
            + S+    + EL EE   +K+  +     +   EE+++  + +E E+    +    +++A
Sbjct: 976  YESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLA 1035

Query: 665  HQQSGSELALRRSQRLAASASTQQ 688
             +Q+  + ++R ++ L A  + +Q
Sbjct: 1036 TKQALEDHSIRHARILEALETEKQ 1059



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 33/151 (21%), Positives = 67/151 (44%), Gaps = 15/151 (9%)

Query: 44  SVVSTSLEDKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKD 103
           +VV  +   K  +  E+S  +V V +RVRP    E          +IE    +V  + K+
Sbjct: 340 TVVQNTSAGKDPLKVENS--QVTVAVRVRPFTKRE----------KIEKASQVVFMSGKE 387

Query: 104 SFALKSNERGIGQATHR---FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYG 160
                 + + +    +    ++F +       Q + +      +++   +G N  ++ YG
Sbjct: 388 ITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYG 447

Query: 161 VTNSGKTHTIQGTIKDGGILPRSLALIFNSL 191
            T SGK++T+ G  ++ GI+PR    +F+ +
Sbjct: 448 QTGSGKSYTMMGFSEEPGIIPRFCEDLFSQV 478


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,738,803
Number of Sequences: 37866
Number of extensions: 1557133
Number of successful extensions: 8527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 740
Number of HSP's that attempted gapping in prelim test: 5545
Number of HSP's gapped (non-prelim): 2401
length of query: 890
length of database: 18,247,518
effective HSP length: 111
effective length of query: 779
effective length of database: 14,044,392
effective search space: 10940581368
effective search space used: 10940581368
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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