BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens] (510 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens] 1043 0.0 gi|75677363 lectin, mannose-binding, 1 like [Homo sapiens] 276 3e-74 gi|5803023 lectin, mannose-binding 2 precursor [Homo sapiens] 160 3e-39 gi|13540594 lectin, mannose-binding 2-like isoform 2 [Homo sapiens] 154 2e-37 gi|214010240 lectin, mannose-binding 2-like isoform 1 [Homo sapi... 150 3e-36 gi|4758650 kinesin family member 5C [Homo sapiens] 45 2e-04 gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 42 0.001 gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 42 0.001 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 41 0.002 gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 40 0.004 gi|4506467 radixin [Homo sapiens] 40 0.005 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 39 0.009 gi|21735548 centrosomal protein 2 [Homo sapiens] 39 0.011 gi|4505257 moesin [Homo sapiens] 39 0.011 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 38 0.019 gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 38 0.019 gi|115529449 upstream binding transcription factor, RNA polymera... 38 0.019 gi|115529451 upstream binding transcription factor, RNA polymera... 38 0.019 gi|7657671 upstream binding transcription factor, RNA polymerase... 38 0.019 gi|110347568 centrosomal protein 152kDa [Homo sapiens] 38 0.019 gi|122937396 coiled-coil domain containing 150 [Homo sapiens] 38 0.019 gi|87298937 centrosomal protein 110kDa [Homo sapiens] 38 0.019 gi|45446749 kinesin family member 5A [Homo sapiens] 38 0.025 gi|149363664 septin 8 isoform d [Homo sapiens] 38 0.025 gi|149363689 septin 8 isoform a [Homo sapiens] 38 0.025 gi|149363661 septin 8 isoform b [Homo sapiens] 38 0.025 gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 38 0.025 gi|239741668 PREDICTED: upstream binding transcription factor, R... 37 0.033 gi|169163306 PREDICTED: upstream binding transcription factor, R... 37 0.033 gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 37 0.033 >gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens] Length = 510 Score = 1043 bits (2696), Expect = 0.0 Identities = 510/510 (100%), Positives = 510/510 (100%) Query: 1 MAGSRQRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEYKYSFKGPHLVQS 60 MAGSRQRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEYKYSFKGPHLVQS Sbjct: 1 MAGSRQRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEYKYSFKGPHLVQS 60 Query: 61 DGTVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGA 120 DGTVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGA Sbjct: 61 DGTVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGA 120 Query: 121 DGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNNPAIVIIGNNGQIHYDHQN 180 DGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNNPAIVIIGNNGQIHYDHQN Sbjct: 121 DGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNNPAIVIIGNNGQIHYDHQN 180 Query: 181 DGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPA 240 DGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPA Sbjct: 181 DGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPA 240 Query: 241 QGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQEL 300 QGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQEL Sbjct: 241 QGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQEL 300 Query: 301 DKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQR 360 DKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQR Sbjct: 301 DKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQR 360 Query: 361 RYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVRLVSGM 420 RYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVRLVSGM Sbjct: 361 RYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVRLVSGM 420 Query: 421 QHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLSTVH 480 QHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLSTVH Sbjct: 421 QHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLSTVH 480 Query: 481 FIIFVVVQTVLFIGYIMYRSQQEAAAKKFF 510 FIIFVVVQTVLFIGYIMYRSQQEAAAKKFF Sbjct: 481 FIIFVVVQTVLFIGYIMYRSQQEAAAKKFF 510 >gi|75677363 lectin, mannose-binding, 1 like [Homo sapiens] Length = 526 Score = 276 bits (706), Expect = 3e-74 Identities = 176/503 (34%), Positives = 269/503 (53%), Gaps = 41/503 (8%) Query: 15 PLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAI 74 PLFC LLL L G P RRFEYK SFKGP L +PFW+H G+AI Sbjct: 9 PLFCLLLLLLDPHSPETGCP-------PLRRFEYKLSFKGPRLALPGAGIPFWSHHGDAI 61 Query: 75 PSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYAENQGLE 134 +++R+ PS++++ G+VW++ F WEVEV RVTG GR GA G+A+WY +G Sbjct: 62 LGLEEVRLTPSMRNRSGAVWSRASVPFSAWEVEVQMRVTGLGRRGAQGMAVWYTRGRGHV 121 Query: 135 GPVFGSADLWNGVGIFFDSFDNDGKKNNPAIVIIGNNGQIHYDHQNDGASQALASCQRDF 194 G V G W+G+GIFFDS D +++PAI ++ ++G I + DGASQ L SC DF Sbjct: 122 GSVLGGLASWDGIGIFFDSPAED-TQDSPAIRVLASDGHIPSEQPGDGASQGLGSCHWDF 180 Query: 195 RNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPAQGHFGISAATGGLA 254 RN+P+P RA+ITY+ L + +N+G TP + EFC V +++ G FG+SAATG LA Sbjct: 181 RNRPHPFRARITYWGQRLRMSLNSGLTP-SDPGEFCVDVGPLLLVPGGFFGVSAATGTLA 239 Query: 255 DDHDVLSFLTFQLTEPGKE-PPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPD 313 DDHDVLSFLTF L+EP E PP P E+ + + Q E + L +++ K + Sbjct: 240 DDHDVLSFLTFSLSEPSPEVPPQPFLEMQQLRLAR-QLEGLWARLGLGTREDVTPKSDSE 298 Query: 314 LQGQPAEEIF---ESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDE--QRRYVSSLTE 368 QG+ E +F E++G R++ + + ++ Q RQ L Q R Sbjct: 299 AQGE-GERLFDLEETLGRH--RRILQALRGLSKQLAQAERQWKKQLGPPGQARPDGGWAL 355 Query: 369 EISKRGAGMPGQHGQITQQ------ELDTVVKTQHEILRQVNEMKNSMSETVRLVSGMQH 422 + S + PG+ G ++ ++ ++ Q +L+ + EM+++ VR+ + Q Sbjct: 356 DASCQIPSTPGRGGHLSMSLNKDSAKVGALLHGQWTLLQALQEMRDA---AVRMAAEAQV 412 Query: 423 PGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFP----SCLST 478 G+ HF+++ L +++ ++ P+ K P P P SCL Sbjct: 413 SYLPVGI---EHHFLELDHILGLLQEELRG------PAKAAAKAPRPPGQPPRASSCLQP 463 Query: 479 VHFIIFVVVQTVLFIGYIMYRSQ 501 F+ ++++QTV F GY+ +R + Sbjct: 464 GIFLFYLLIQTVGFFGYVHFRQE 486 >gi|5803023 lectin, mannose-binding 2 precursor [Homo sapiens] Length = 356 Score = 160 bits (405), Expect = 3e-39 Identities = 91/270 (33%), Positives = 142/270 (52%), Gaps = 20/270 (7%) Query: 15 PLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAI 74 PLF LLL V D G+ + ++S P+ ++P W G+ + Sbjct: 32 PLFLLLLLGS---VTADITDGNS------EHLKREHSLIKPYQGVGSSSMPLWDFQGSTM 82 Query: 75 PSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGR--IGADGLAIWYAENQG 132 +S +R+ P +S+ GS+W ++WE+ V F+V G G+ + DG+A+WY ++ Sbjct: 83 LTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRL 142 Query: 133 LEGPVFGSADLWNGVGIFFDSFDNDGKKNN--PAIVIIGNNGQIHYDHQNDGASQALASC 190 + GPVFGS D ++G+ IF D++ ND P I ++ NNG + YDH DG LA C Sbjct: 143 VPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGC 202 Query: 191 QRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPAQGHFGISAAT 250 DFRN+ + + Y + LTVM + DKN+++ C + + +P +FG SA T Sbjct: 203 TADFRNRDHDTFLAVRYSRGRLTVMTD---LEDKNEWKNCIDITGVRLPTGYYFGASAGT 259 Query: 251 GGLADDHDVLSFLTFQLTEPGKEPPTPDKE 280 G L+D+HD++S FQL TPD+E Sbjct: 260 GDLSDNHDIISMKLFQL----MVEHTPDEE 285 >gi|13540594 lectin, mannose-binding 2-like isoform 2 [Homo sapiens] Length = 348 Score = 154 bits (389), Expect = 2e-37 Identities = 90/271 (33%), Positives = 144/271 (53%), Gaps = 18/271 (6%) Query: 6 QRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEY---KYSFKGPHLVQSDG 62 +R L AR LLL LG G P + FEY ++S P+ G Sbjct: 15 RRCLSARDGSRMLLLLLLLGS-------GQGPQQVGAGQTFEYLKREHSLSKPYQGVGTG 67 Query: 63 TVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGR--IGA 120 + W GNA+ + IR+ P ++S++G++W + +WE++V F++ G+G+ + Sbjct: 68 SSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHG 127 Query: 121 DGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNN---PAIVIIGNNGQIHYD 177 DGLAIWY +++ GPVFG+ D + G+G+F D++ N+ K+ P I + NNG + YD Sbjct: 128 DGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLSYD 187 Query: 178 HQNDGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMI 237 H+ DG L C RN Y I Y + LT+M++ K+++ C +V + Sbjct: 188 HERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMD---IDGKHEWRDCIEVPGVR 244 Query: 238 IPAQGHFGISAATGGLADDHDVLSFLTFQLT 268 +P +FG S+ TG L+D+HDV+S F+LT Sbjct: 245 LPRGYYFGTSSITGDLSDNHDVISLKLFELT 275 Score = 29.6 bits (65), Expect = 6.8 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 7/59 (11%) Query: 458 MPSNEKPKCPE----LPPFPSCLSTVHFIIFVVVQTV--LFIGYIMYRSQQEAAAKKFF 510 +PS + K PE LPP S L+ + F +V +V + IG I+Y QE + K+F+ Sbjct: 291 LPSVDNMKLPEMTAPLPPL-SGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY 348 >gi|214010240 lectin, mannose-binding 2-like isoform 1 [Homo sapiens] Length = 359 Score = 150 bits (378), Expect = 3e-36 Identities = 90/282 (31%), Positives = 144/282 (51%), Gaps = 29/282 (10%) Query: 6 QRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEY---KYSFKGPHLVQSDG 62 +R L AR LLL LG G P + FEY ++S P+ G Sbjct: 15 RRCLSARDGSRMLLLLLLLGS-------GQGPQQVGAGQTFEYLKREHSLSKPYQGVGTG 67 Query: 63 TVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGR--IGA 120 + W GNA+ + IR+ P ++S++G++W + +WE++V F++ G+G+ + Sbjct: 68 SSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHG 127 Query: 121 DGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNN--------------PAIV 166 DGLAIWY +++ GPVFG+ D + G+G+F D++ N+ K+ P I Sbjct: 128 DGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQEAQKRRYSPGVQRVFPYIS 187 Query: 167 IIGNNGQIHYDHQNDGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKND 226 + NNG + YDH+ DG L C RN Y I Y + LT+M++ K++ Sbjct: 188 AMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMD---IDGKHE 244 Query: 227 YEFCAKVENMIIPAQGHFGISAATGGLADDHDVLSFLTFQLT 268 + C +V + +P +FG S+ TG L+D+HDV+S F+LT Sbjct: 245 WRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELT 286 Score = 29.6 bits (65), Expect = 6.8 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 7/59 (11%) Query: 458 MPSNEKPKCPE----LPPFPSCLSTVHFIIFVVVQTV--LFIGYIMYRSQQEAAAKKFF 510 +PS + K PE LPP S L+ + F +V +V + IG I+Y QE + K+F+ Sbjct: 302 LPSVDNMKLPEMTAPLPPL-SGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY 359 >gi|4758650 kinesin family member 5C [Homo sapiens] Length = 957 Score = 45.1 bits (105), Expect = 2e-04 Identities = 52/221 (23%), Positives = 93/221 (42%), Gaps = 39/221 (17%) Query: 281 ISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRE--LRQVFEGQ 338 IS +EKEKY EE ++LD K +E + Q Q AE++ + + D++ L Sbjct: 409 ISTEEKEKYDEEISSLYRQLDDKDDEINQ-----QSQLAEKLKQQMLDQDELLASTRRDY 463 Query: 339 NRIHLEIKQLNRQLDMILDEQRRYVSSLTE------EISKRGAGMPGQHGQITQ---QEL 389 +I E+ +L + + DE + + +L E + S+ + Q+T Q+ Sbjct: 464 EKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKT 523 Query: 390 DTVVKTQHEILRQVNEMKNSMSETVRLVSG--MQHPGSAGGVYETT-------------Q 434 T+ TQ E L Q+ E+ N + + ++ G GG+ T + Sbjct: 524 TTLTTTQRE-LSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEE 582 Query: 435 HFIDIKEHLHIVKRDIDNLVQRN-------MPSNEKPKCPE 468 F + ++ +K ++ +LV R+ M SN K E Sbjct: 583 EFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASE 623 >gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] Length = 3907 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/140 (20%), Positives = 63/140 (45%), Gaps = 4/140 (2%) Query: 283 EKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVF-EGQNRI 341 EKE +E+ E F++EL+ K EE Q+ H L+ Q E + ++F + ++ Sbjct: 2202 EKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL 2261 Query: 342 HLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILR 401 L IK+ + M +Q + I ++ + + Q+T+ + + T ++++ Sbjct: 2262 GLAIKESDA---MSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIE 2318 Query: 402 QVNEMKNSMSETVRLVSGMQ 421 + NE+ + + + Q Sbjct: 2319 EKNELIRDLETQIECLMSDQ 2338 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 9/63 (14%) Query: 290 QEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLN 349 +E+ E +QEL ++ +E Q+ A E+ R++ + E Q ++ EIK+LN Sbjct: 1584 EEQLEDMRQELVRQYQEHQQ---------ATELLRQAHMRQMERQREDQEQLQEEIKRLN 1634 Query: 350 RQL 352 RQL Sbjct: 1635 RQL 1637 Score = 32.3 bits (72), Expect = 1.1 Identities = 29/156 (18%), Positives = 69/156 (44%), Gaps = 15/156 (9%) Query: 252 GLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGH 311 G D +L+ L ++ E G E + + + ++ E + +++ +K ++ Sbjct: 3053 GTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQ 3112 Query: 312 PDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEIS 371 +P++E+ E ++ Q+ E Q + +K +L L ++ V+ L E++ Sbjct: 3113 ES--EKPSQELLEYNIQQKQSQMLEMQVELS-SMKDRATELQEQLSSEKMVVAELKSELA 3169 Query: 372 KRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMK 407 + T+ EL+T +K QH+ L+++ + Sbjct: 3170 Q------------TKLELETTLKAQHKHLKELEAFR 3193 Score = 30.4 bits (67), Expect = 4.0 Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Query: 263 LTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEI 322 +T Q+ E KE +E EKEK ++E + Q + + +++ ++ DLQ + A+ Sbjct: 717 MTLQINELQKEIEILRQE--EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 774 Query: 323 FESVGDRELRQVFEGQNRIHLEIKQLNR 350 E+ ++ ++ E +IH + Q R Sbjct: 775 AENSILKDEKKTLEDMLKIHTPVSQEER 802 >gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] Length = 3899 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/140 (20%), Positives = 63/140 (45%), Gaps = 4/140 (2%) Query: 283 EKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVF-EGQNRI 341 EKE +E+ E F++EL+ K EE Q+ H L+ Q E + ++F + ++ Sbjct: 2194 EKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL 2253 Query: 342 HLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILR 401 L IK+ + M +Q + I ++ + + Q+T+ + + T ++++ Sbjct: 2254 GLAIKESDA---MSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIE 2310 Query: 402 QVNEMKNSMSETVRLVSGMQ 421 + NE+ + + + Q Sbjct: 2311 EKNELIRDLETQIECLMSDQ 2330 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 9/63 (14%) Query: 290 QEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLN 349 +E+ E +QEL ++ +E Q+ A E+ R++ + E Q ++ EIK+LN Sbjct: 1584 EEQLEDMRQELVRQYQEHQQ---------ATELLRQAHMRQMERQREDQEQLQEEIKRLN 1634 Query: 350 RQL 352 RQL Sbjct: 1635 RQL 1637 Score = 32.3 bits (72), Expect = 1.1 Identities = 29/156 (18%), Positives = 69/156 (44%), Gaps = 15/156 (9%) Query: 252 GLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGH 311 G D +L+ L ++ E G E + + + ++ E + +++ +K ++ Sbjct: 3045 GTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQ 3104 Query: 312 PDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEIS 371 +P++E+ E ++ Q+ E Q + +K +L L ++ V+ L E++ Sbjct: 3105 ES--EKPSQELLEYNIQQKQSQMLEMQVELS-SMKDRATELQEQLSSEKMVVAELKSELA 3161 Query: 372 KRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMK 407 + T+ EL+T +K QH+ L+++ + Sbjct: 3162 Q------------TKLELETTLKAQHKHLKELEAFR 3185 Score = 30.4 bits (67), Expect = 4.0 Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Query: 263 LTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEI 322 +T Q+ E KE +E EKEK ++E + Q + + +++ ++ DLQ + A+ Sbjct: 717 MTLQINELQKEIEILRQE--EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 774 Query: 323 FESVGDRELRQVFEGQNRIHLEIKQLNR 350 E+ ++ ++ E +IH + Q R Sbjct: 775 AENSILKDEKKTLEDMLKIHTPVSQEER 802 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 41.2 bits (95), Expect = 0.002 Identities = 45/166 (27%), Positives = 76/166 (45%), Gaps = 14/166 (8%) Query: 253 LADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHP 312 L + +++S L QLT+ E P + EEF +Q+L +K+E Sbjct: 153 LQEKEELISTLQAQLTQAQAEQPA--------QSSTEMEEFVMMKQQLQEKEEFISTLQA 204 Query: 313 DLQGQPAEEIFESVGDRELRQVFEGQNRIHL-EIKQLNRQLDMILDEQRRYVSSLTEEIS 371 L AE+ + V RE FE Q R+H E+ QL Q D+ + Q++ + L ++ Sbjct: 205 QLSQTQAEQAAQQV-VREKDARFETQVRLHEDELLQLVTQADVETEMQQK-LRVLQRKLE 262 Query: 372 KRGAGMPG--QHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVR 415 + + G Q + QQEL T + +++IL Q + + T+R Sbjct: 263 EHEESLVGRAQVVDLLQQEL-TAAEQRNQILSQQLQQMEAEHNTLR 307 Score = 29.3 bits (64), Expect = 8.9 Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 19/137 (13%) Query: 279 KEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAE-EIFESVGDRELRQVFEG 337 KEI E EK + + + EL KK EE + + Q E E ++V +V Sbjct: 1312 KEI-EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEA--EVHAE 1368 Query: 338 QNRIHLEIKQLN-------RQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELD 390 + LE QL R+L LDE ++ +S E++S GQ++++E Sbjct: 1369 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLS-------GQLSEKEA- 1420 Query: 391 TVVKTQHEILRQVNEMK 407 + K Q EI+ Q + +K Sbjct: 1421 ALTKIQTEIIEQEDLIK 1437 >gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] Length = 1498 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/123 (22%), Positives = 62/123 (50%), Gaps = 8/123 (6%) Query: 288 KYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQ 347 K+ +E FQ EL + + + Q L Q +++ VG++E+ + ++ EI+ Sbjct: 1246 KHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQ---PVGNQEMENLKWEVDQKEREIQS 1302 Query: 348 LNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMK 407 L +QLD+ + R+ + L + + + + ++ Q++L K + + +V+E+K Sbjct: 1303 LKQQLDLTEQQGRKELEGLQQLLQNVKSEL-----EMAQEDLSMTQKDKFMLQAKVSELK 1357 Query: 408 NSM 410 N+M Sbjct: 1358 NNM 1360 Score = 30.0 bits (66), Expect = 5.2 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 11/132 (8%) Query: 269 EPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQK-GHPDLQGQPAEEIFE--- 324 E G E + E +E + EH QQE K++ QK LQ + E + Sbjct: 800 EEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDA 859 Query: 325 SVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTE------EISKRGAGMP 378 + D+ + ++ + R+ E+K+L ++L + E+R + L+ ++ + A + Sbjct: 860 TSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLE 919 Query: 379 GQHGQITQQELD 390 G H Q Q+E D Sbjct: 920 G-HLQSAQKERD 930 Score = 29.3 bits (64), Expect = 8.9 Identities = 36/162 (22%), Positives = 71/162 (43%), Gaps = 23/162 (14%) Query: 297 QQELDKKKEEFQKGHPD----LQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQL 352 ++ELD+ ++G + L+ E +S L+Q + +IK+ Q Sbjct: 789 KEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQ 848 Query: 353 DMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVN-EMKNSMS 411 ++++ RR +S + IS+ A T++ LD+ +K + L QV+ E + + + Sbjct: 849 KVMVEAYRRDATSKDQLISELKA---------TRKRLDSELKELRQELMQVHGEKRTAEA 899 Query: 412 ETVRLVSGMQHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNL 453 E RL V + QH D++ HL +++ D + Sbjct: 900 ELSRLHRE---------VAQVRQHMADLEGHLQSAQKERDEM 932 >gi|4506467 radixin [Homo sapiens] Length = 583 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/124 (23%), Positives = 58/124 (46%), Gaps = 7/124 (5%) Query: 282 SEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRI 341 ++ +EK+Q++ E Q E +KKK E + + + EE+ E L+Q+ E + Sbjct: 307 AQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELME-----RLKQIEEQTIKA 361 Query: 342 HLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILR 401 E+++ R+ + LD++R+ E + K I +Q D +K Q ++ Sbjct: 362 QKELEEQTRKA-LELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQ-MKNQEQLAA 419 Query: 402 QVNE 405 ++ E Sbjct: 420 ELAE 423 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 3/79 (3%) Query: 266 QLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFES 325 QL E +EI+EKEKE+ + E E + L + +E+ K +L+ Q + + Sbjct: 317 QLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKAL--- 373 Query: 326 VGDRELRQVFEGQNRIHLE 344 D+E ++ E R+ E Sbjct: 374 ELDQERKRAKEEAERLEKE 392 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 39.3 bits (90), Expect = 0.009 Identities = 50/242 (20%), Positives = 98/242 (40%), Gaps = 18/242 (7%) Query: 246 ISAATGGLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKE 305 + A L D L+ +T QL + + DK+ + E + +E++ L++K E Sbjct: 669 LDTAQNALQDKQQELNKITTQLDQVTAK--LQDKQEHCSQLESHLKEYKEKYLSLEQKTE 726 Query: 306 EFQKGHPDLQGQPAE-EIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVS 364 E + L+ E + + ++L+Q + + L +L++QL+M ++ VS Sbjct: 727 ELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEM----EKEIVS 782 Query: 365 SLTEEISKRGAGMPGQHGQITQQELD-TVVKTQHEILRQV-----NEMKNSMSETVRLVS 418 S ++ K+ + ++T+QE + ++K E L Q E+ N + TV + Sbjct: 783 STRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQ 842 Query: 419 GMQHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLST 478 ++ A +K+ L V + N N+K K L +C Sbjct: 843 KVKMEKEA-----LMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL 897 Query: 479 VH 480 H Sbjct: 898 KH 899 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 38.9 bits (89), Expect = 0.011 Identities = 34/164 (20%), Positives = 76/164 (46%), Gaps = 20/164 (12%) Query: 257 HDVLSFLTF---QLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPD 313 HD+ S T +L E +E + ++I E +++K EH Q+L+++ +E Sbjct: 1612 HDLESHSTVLARELQERDQEVKSQREQIEELQRQK-----EHLTQDLERRDQELMLQKER 1666 Query: 314 LQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKR 373 +Q + E R+ + + E +I L +++ R+ L QR+ + EE Sbjct: 1667 IQ------VLEDQRTRQTKILEEDLEQIKLSLRERGRE----LTTQRQLMQERAEEGKGP 1716 Query: 374 GAGMPG--QHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVR 415 G +H ++ ++ + V+ Q E + ++ E+K+ + + ++ Sbjct: 1717 SKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQ 1760 Score = 37.7 bits (86), Expect = 0.025 Identities = 33/131 (25%), Positives = 63/131 (48%), Gaps = 15/131 (11%) Query: 284 KEKEKYQEEFEHFQQELDKKKEE---FQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNR 340 KE+E Q+ E +Q+L+ ++E ++ + +LQ Q GD Q E Q Sbjct: 463 KERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQ---------GDSAQGQKEEQQEE 513 Query: 341 IHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQH--GQITQQELDTVVKTQHE 398 +HL +++ R +M++ + + SL+E I+ R A + H G++ +QE V Sbjct: 514 LHLAVRERERLQEMLMGLEAKQSESLSELITLREA-LESSHLEGELLRQEQTEVTAALAR 572 Query: 399 ILRQVNEMKNS 409 + + E+ +S Sbjct: 573 AEQSIAELSSS 583 Score = 35.4 bits (80), Expect = 0.12 Identities = 34/145 (23%), Positives = 66/145 (45%), Gaps = 22/145 (15%) Query: 283 EKEKEKYQEEFEHFQQELDKKKE--EFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNR 340 EK++E + EH EL+KK + E Q+G +++ + + E + +N Sbjct: 1514 EKDRETQRNVLEHQLLELEKKDQMIESQRGQ-------VQDLKKQLVTLECLALELEENH 1566 Query: 341 IHLEIKQ-LNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQ------------Q 387 +E +Q L ++L+ + QR ++ LT ++ +R + Q QI Q Sbjct: 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQ 1626 Query: 388 ELDTVVKTQHEILRQVNEMKNSMSE 412 E D VK+Q E + ++ K +++ Sbjct: 1627 ERDQEVKSQREQIEELQRQKEHLTQ 1651 Score = 33.9 bits (76), Expect = 0.36 Identities = 32/153 (20%), Positives = 68/153 (44%), Gaps = 13/153 (8%) Query: 278 DKEISEKEKEKYQEEFEHFQQELDKKKEE-----FQKGHPDLQGQPAEEIFESVGDRELR 332 ++E+ EK +E +E+ Q+EL+++K +K L Q A +S+ +EL Sbjct: 1030 EQEVQEKLRET--QEYNRIQKELEREKASLTLSLMEKEQRLLVLQEA----DSIRQQELS 1083 Query: 333 QVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTV 392 + + E K+L+ Q++++ E + + + ++ + H IT+Q+L Sbjct: 1084 ALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASH--ITEQQLRAS 1141 Query: 393 VKTQHEILRQVNEMKNSMSETVRLVSGMQHPGS 425 + Q Q+ S + ++ Q PG+ Sbjct: 1142 LWAQEAKAAQLQLRLRSTESQLEALAAEQQPGN 1174 Score = 33.5 bits (75), Expect = 0.47 Identities = 40/194 (20%), Positives = 79/194 (40%), Gaps = 22/194 (11%) Query: 266 QLTEPGKEPPTPDKEISEKE----KEKYQEEFEHFQQELDKKKEEFQKGHPDL-----QG 316 Q + GK K EKE +EK+++E QQEL K E ++ +L + Sbjct: 835 QAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQ 894 Query: 317 QPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAG 376 Q E ++ + E Q ++ LE ++ L L + ++ ++ ++++ + Sbjct: 895 QTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQD 954 Query: 377 MPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVRLVSGMQHPGSAGGVYETTQHF 436 M Q ++ +QE +++T Q+ E + + E R QH + E + Sbjct: 955 MKVQ--KLKEQETTGILQT------QLQEAQRELKEAAR-----QHRDDLAALQEESSSL 1001 Query: 437 IDIKEHLHIVKRDI 450 + K L D+ Sbjct: 1002 LQDKMDLQKQVEDL 1015 >gi|4505257 moesin [Homo sapiens] Length = 577 Score = 38.9 bits (89), Expect = 0.011 Identities = 29/131 (22%), Positives = 63/131 (48%), Gaps = 7/131 (5%) Query: 282 SEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRI 341 ++ +EK+Q++ E E +KKK E + + + EE+ E L+Q+ E + Sbjct: 307 AQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELME-----RLKQIEEQTKKA 361 Query: 342 HLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILR 401 E+++ R+ + L+++R+ S E+++K + Q D KTQ ++ Sbjct: 362 QQELEEQTRRA-LELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQ-KKTQEQLAL 419 Query: 402 QVNEMKNSMSE 412 ++ E+ +S+ Sbjct: 420 EMAELTARISQ 430 Score = 33.5 bits (75), Expect = 0.47 Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 27/144 (18%) Query: 279 KEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQ----------------PAEEI 322 +E++EKEKEK + E E + L + +E+ +K +L+ Q AE++ Sbjct: 330 REMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKL 389 Query: 323 FESVGDRE---------LRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKR 373 + + E R + Q ++ LE+ +L ++ + +++ S E K Sbjct: 390 AKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQK- 448 Query: 374 GAGMPGQHGQITQQELDTVVKTQH 397 A M + + T+ EL T + T H Sbjct: 449 -AQMVQEDLEKTRAELKTAMSTPH 471 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 38.1 bits (87), Expect = 0.019 Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 8/147 (5%) Query: 266 QLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFES 325 Q+ E + ++++ E+E++ ++E + +QE +K+E Q G + Q Q EE + Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQ- 251 Query: 326 VGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQIT 385 ++ Q+ + + ++ + +Q+ Q + +L ++ + + E+ ++ M Q Q+ Sbjct: 252 ---KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ--TEQEEQTGEQEEQMREQEEQMR 306 Query: 386 QQELDTVVKTQHEILRQVNEMKNSMSE 412 +QE ++ Q E +R+ E E Sbjct: 307 EQE--EQMREQEEQMREQEEQMGKQEE 331 Score = 36.6 bits (83), Expect = 0.056 Identities = 31/137 (22%), Positives = 74/137 (54%), Gaps = 6/137 (4%) Query: 266 QLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFES 325 Q+ E + + ++ E+E + ++E + +QE +++E Q G + +GQ E+ E Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMG--EQEGQMGEQ-EEQ 207 Query: 326 VGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQIT 385 +G++E Q+ + + ++ + +Q+ +Q + + EQ V E++ K+ M Q Q+ Sbjct: 208 MGEQE-EQMQKQEEQMGEQEEQMRKQEEQ-MGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265 Query: 386 QQELDTVVKTQHEILRQ 402 +QE + + + + ++L+Q Sbjct: 266 EQE-EQMREQEEQMLKQ 281 Score = 35.8 bits (81), Expect = 0.095 Identities = 32/154 (20%), Positives = 74/154 (48%), Gaps = 16/154 (10%) Query: 266 QLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFES 325 Q+ E + + ++ E+E + ++E + +QE +K+E Q G + Q + E E Sbjct: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE---EQ 235 Query: 326 VGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQIT 385 +G++E QV + + ++ + +Q+ +Q + + +++ E++ ++ M Q Q Sbjct: 236 MGEQE-EQVQKQEEQVQKQEEQMRKQEEQMREQE--------EQMREQEEQMLKQKEQTE 286 Query: 386 QQ----ELDTVVKTQHEILRQVNEMKNSMSETVR 415 Q+ E + ++ Q E +R+ E E +R Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMR 320 Score = 35.4 bits (80), Expect = 0.12 Identities = 34/148 (22%), Positives = 65/148 (43%), Gaps = 13/148 (8%) Query: 266 QLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFES 325 Q+ E + + ++ E+E + ++E + +QE ++E Q G + Q Q EE Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEE---- 220 Query: 326 VGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQIT 385 Q+ E + ++ + +Q+ Q + + +Q V E++ K+ M Q Q+ Sbjct: 221 -------QMGEQEEQMRKQEEQMGEQEEQV-QKQEEQVQKQEEQMRKQEEQMREQEEQMR 272 Query: 386 QQELDTV-VKTQHEILRQVNEMKNSMSE 412 +QE + K Q E Q E + M E Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMRE 300 Score = 33.5 bits (75), Expect = 0.47 Identities = 36/173 (20%), Positives = 78/173 (45%), Gaps = 26/173 (15%) Query: 266 QLTEPGKEPPTPDKEISEKEKE-KYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIF- 323 Q+ E ++ ++++ E+E++ + QEE Q+E +K+EE + + + E++ Sbjct: 221 QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280 Query: 324 --------ESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILD-------------EQRRY 362 E G++E Q+ E + ++ + +Q+ Q + + + EQ+ Sbjct: 281 QKEQTEQEEQTGEQE-EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339 Query: 363 VSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVR 415 + E++ K+ M Q Q+ +QE V+ Q E +R+ E E +R Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQKQE--EQVRKQEEQMRKQEEQMRKQEEQMR 390 >gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sapiens] Length = 525 Score = 38.1 bits (87), Expect = 0.019 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 5/105 (4%) Query: 267 LTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESV 326 LTEP +E P +E+E+E+ +EE E ++E +++ E Q G PAEE Sbjct: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQ-GEQPKPASPAEEDKMPP 355 Query: 327 GDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEIS 371 D + + + + ++ R L + + +L +EIS Sbjct: 356 YDEQTQAFIDAAQEARNKFEEAERS----LKDMEESIRNLEQEIS 396 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 38.1 bits (87), Expect = 0.019 Identities = 15/36 (41%), Positives = 25/36 (69%) Query: 279 KEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDL 314 KE+ EK+K KY ++F+ +QE ++ F++ HPDL Sbjct: 151 KELPEKKKMKYIQDFQREKQEFERNLARFREDHPDL 186 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 38.1 bits (87), Expect = 0.019 Identities = 15/36 (41%), Positives = 25/36 (69%) Query: 279 KEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDL 314 KE+ EK+K KY ++F+ +QE ++ F++ HPDL Sbjct: 151 KELPEKKKMKYIQDFQREKQEFERNLARFREDHPDL 186 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 38.1 bits (87), Expect = 0.019 Identities = 15/36 (41%), Positives = 25/36 (69%) Query: 279 KEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDL 314 KE+ EK+K KY ++F+ +QE ++ F++ HPDL Sbjct: 151 KELPEKKKMKYIQDFQREKQEFERNLARFREDHPDL 186 >gi|110347568 centrosomal protein 152kDa [Homo sapiens] Length = 1654 Score = 38.1 bits (87), Expect = 0.019 Identities = 30/127 (23%), Positives = 66/127 (51%), Gaps = 7/127 (5%) Query: 291 EEFEHFQQE-LDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLN 349 ++F+H +QE +D+ + +Q+ H ++ Q E + E +Q+FE R HL QL Sbjct: 661 QDFDHDKQEAVDRCERTYQQHHEAMKTQIRESLLAKHA-LEKQQLFEAYERTHL---QLR 716 Query: 350 RQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQV-NEMKN 408 +LD L+++ V E+ + + + T++E T K + ++++Q+ E ++ Sbjct: 717 SELDK-LNKEVTAVQECYLEVCREKDNLELTLRKTTEKEQQTQEKIKEKLIQQLEKEWQS 775 Query: 409 SMSETVR 415 + +T++ Sbjct: 776 KLDQTIK 782 Score = 31.6 bits (70), Expect = 1.8 Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 7/126 (5%) Query: 291 EEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNR 350 + FE QQ+ E + +Q Q + +R+L + E N +I+ LN Sbjct: 216 DTFEGLQQQFLGANENSAENMQIIQLQ----VLNKAKERQLENLIEKLNESERQIRYLNH 271 Query: 351 QLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSM 410 QL +I DE+ SL E + G+ +I + ++TQ + L+ E Sbjct: 272 QLVIIKDEKDGLTLSLRE---SQKLFQNGKEREIQLEAQIKALETQIQALKVNEEQMIKK 328 Query: 411 SETVRL 416 S T + Sbjct: 329 SRTTEM 334 Score = 29.6 bits (65), Expect = 6.8 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 11/82 (13%) Query: 359 QRRYVSSLTEEISKRGAGM------PGQHGQ-----ITQQELDTVVKTQHEILRQVNEMK 407 ++R ++ L+++ + +G G G H Q T+ E + K E++ + N+MK Sbjct: 1114 KKRNMAELSKDSASQGTGQGDPGPAAGHHAQPLALQATEAEAEENNKVVEELIEENNDMK 1173 Query: 408 NSMSETVRLVSGMQHPGSAGGV 429 N + E L SAG + Sbjct: 1174 NKLEELQTLCKTPPRSLSAGAI 1195 >gi|122937396 coiled-coil domain containing 150 [Homo sapiens] Length = 1101 Score = 38.1 bits (87), Expect = 0.019 Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 6/194 (3%) Query: 280 EISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQN 339 E S +EK+ EE E FQ+E++K ++E + +L+ + A+ + Q E +N Sbjct: 461 EASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINTLTHNLQTLEEEN 520 Query: 340 RIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHG--QITQQELDTVVKTQH 397 + HL + + +L + + E+I++ + ++G QI ++L+ V++ Sbjct: 521 K-HLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQIKVKQLEEQVQSFT 579 Query: 398 EILRQVNEMK--NSMSETVRLVSGMQHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQ 455 + Q + ++ N +T + + + + H ++K L K ++ V+ Sbjct: 580 DTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVKSILERSKEELSRTVK 639 Query: 456 -RNMPSNEKPKCPE 468 RN E K E Sbjct: 640 CRNAALKESQKLKE 653 >gi|87298937 centrosomal protein 110kDa [Homo sapiens] Length = 2325 Score = 38.1 bits (87), Expect = 0.019 Identities = 31/133 (23%), Positives = 60/133 (45%), Gaps = 5/133 (3%) Query: 280 EISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQN 339 E KEKE QE+ + ++++L + K + + + + + R+L+Q + N Sbjct: 1783 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN 1842 Query: 340 RIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEI 399 R L + + L E+R V+SL EE++ H + +Q+L K Q + Sbjct: 1843 RDKLSLHNDISAMQQQLQEKREAVNSLQEELAN-----VQDHLNLAKQDLLHTTKHQDVL 1897 Query: 400 LRQVNEMKNSMSE 412 L + ++ +SE Sbjct: 1898 LSEQTRLQKDISE 1910 >gi|45446749 kinesin family member 5A [Homo sapiens] Length = 1032 Score = 37.7 bits (86), Expect = 0.025 Identities = 31/134 (23%), Positives = 60/134 (44%), Gaps = 12/134 (8%) Query: 281 ISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDR-ELRQVFEGQN 339 I+ +E++KY+EE ++LD K +E + Q Q E++ + + D+ EL G N Sbjct: 409 IAPEERQKYEEEIRRLYKQLDDKDDEINQ-----QSQLIEKLKQQMLDQEELLVSTRGDN 463 Query: 340 -RIHLEIKQLNRQLDMILDEQRRYVSSLTE-----EISKRGAGMPGQHGQITQQELDTVV 393 ++ E+ L + D DE + + +L E + + Q Q+ EL V Sbjct: 464 EKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKV 523 Query: 394 KTQHEILRQVNEMK 407 T + ++ ++ Sbjct: 524 ATMLSLESELQRLQ 537 Score = 32.0 bits (71), Expect = 1.4 Identities = 32/181 (17%), Positives = 82/181 (45%), Gaps = 11/181 (6%) Query: 280 EISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQN 339 E++ K+KE ++ + ++ L+ + E ++ H + +EI E + + ++ + Sbjct: 679 EVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEK--QKTIDELKDLNQ 736 Query: 340 RIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEI 399 ++ LE+++L + + E+ + L E + +H Q ++Q+L + +T Sbjct: 737 KLQLELEKLQADYEKLKSEEHEKSTKLQEL-----TFLYERHEQ-SKQDLKGLEETVARE 790 Query: 400 LRQVNEMKNSMSETVRL---VSGMQHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQR 456 L+ ++ ++ + V S P +GG++ Q ++ +L + + LV+ Sbjct: 791 LQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRD 850 Query: 457 N 457 N Sbjct: 851 N 851 >gi|149363664 septin 8 isoform d [Homo sapiens] Length = 369 Score = 37.7 bits (86), Expect = 0.025 Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 16/123 (13%) Query: 286 KEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEI 345 +E Y+ + + F EL +K+EE ++ + + E+ E +REL + FE R+H E Sbjct: 263 QETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEK--ERELHEKFEHLKRVHQEE 320 Query: 346 KQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNE 405 K+ ++E+RR + T ++R A + Q + T + LR+ + Sbjct: 321 KRK-------VEEKRRELEEETNAFNRRKAAVEALQSQ-------ALHATSQQPLRKDKD 366 Query: 406 MKN 408 KN Sbjct: 367 KKN 369 >gi|149363689 septin 8 isoform a [Homo sapiens] Length = 483 Score = 37.7 bits (86), Expect = 0.025 Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 16/123 (13%) Query: 286 KEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEI 345 +E Y+ + + F EL +K+EE ++ + + E+ E +REL + FE R+H E Sbjct: 323 QETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEK--ERELHEKFEHLKRVHQEE 380 Query: 346 KQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNE 405 K+ ++E+RR + T ++R A + Q + T + LR+ + Sbjct: 381 KRK-------VEEKRRELEEETNAFNRRKAAVEALQSQ-------ALHATSQQPLRKDKD 426 Query: 406 MKN 408 KN Sbjct: 427 KKN 429 >gi|149363661 septin 8 isoform b [Homo sapiens] Length = 429 Score = 37.7 bits (86), Expect = 0.025 Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 16/123 (13%) Query: 286 KEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEI 345 +E Y+ + + F EL +K+EE ++ + + E+ E +REL + FE R+H E Sbjct: 323 QETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEK--ERELHEKFEHLKRVHQEE 380 Query: 346 KQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNE 405 K+ ++E+RR + T ++R A + Q + T + LR+ + Sbjct: 381 KRK-------VEEKRRELEEETNAFNRRKAAVEALQSQ-------ALHATSQQPLRKDKD 426 Query: 406 MKN 408 KN Sbjct: 427 KKN 429 >gi|157042792 coiled-coil domain containing 64B [Homo sapiens] Length = 508 Score = 37.7 bits (86), Expect = 0.025 Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 32/178 (17%) Query: 266 QLTEPGKEPPT--PDKEISEKEKE--KYQEEFEHFQQELDKKKEEFQKGHPDLQGQ--PA 319 ++ EP K+ + P + + EKE E K Q+E Q EL +EE Q+ +L+ Q P Sbjct: 339 EILEPPKKRTSLSPAEILEEKEVEVAKLQDEISLQQAELQSLREELQR-QKELRAQEDPG 397 Query: 320 EEIFESVGDRE--LRQVFE---GQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRG 374 E + ++ DR+ + + E NR+ LE L+R+L + R +LT+E+ Sbjct: 398 EALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAI----RQKVALTQEL---- 449 Query: 375 AGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVRLV----SGMQHPGSAGG 428 + Q ++ V+ Q RQ ++ S T R S PG AGG Sbjct: 450 --------EAWQDDMQVVIGQQLRSQRQKELSASASSSTPRRAAPRFSLRLGPGPAGG 499 >gi|239741668 PREDICTED: upstream binding transcription factor, RNA polymerase I-like 3 [Homo sapiens] Length = 457 Score = 37.4 bits (85), Expect = 0.033 Identities = 15/36 (41%), Positives = 26/36 (72%) Query: 279 KEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDL 314 KE+ E+ K+KY ++F+ +QE ++K F++ HPDL Sbjct: 203 KELPEQMKQKYIQDFQKEKQEFEEKLVRFREEHPDL 238 >gi|169163306 PREDICTED: upstream binding transcription factor, RNA polymerase I-like 5 [Homo sapiens] Length = 471 Score = 37.4 bits (85), Expect = 0.033 Identities = 15/36 (41%), Positives = 26/36 (72%) Query: 279 KEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDL 314 KE+ E+ K+KY ++F+ +QE ++K F++ HPDL Sbjct: 217 KELPEQMKQKYIQDFQKEKQEFEEKLVRFREEHPDL 252 >gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapiens] Length = 1002 Score = 37.4 bits (85), Expect = 0.033 Identities = 41/216 (18%), Positives = 85/216 (39%), Gaps = 19/216 (8%) Query: 253 LADDHDVLSFLTFQLTEPGKEPPTPDKEISEK------EKEKYQEEFEHFQQELDKKKEE 306 L + D L ++ T+ ++ E+ EK EK Q E Q++L+ + Sbjct: 289 LTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELL 348 Query: 307 FQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSL 366 Q+ + A + +L+Q E + ++ + Q+ + + E+ +Y +L Sbjct: 349 LQQFSSRCEAPDANQ--------QLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENL 400 Query: 367 TEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVRLVSGMQHPGSA 426 E + M Q Q +++ T+ + + + +V E++ S++E ++ P Sbjct: 401 KGE-----SAMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPP 455 Query: 427 GGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNE 462 G E Q EHL + +Q + NE Sbjct: 456 AGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNE 491 Score = 32.3 bits (72), Expect = 1.1 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 13/168 (7%) Query: 260 LSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQG--- 316 L+ L Q+ EP PP P SE E++ Q E EH ++EL+ + Q D +G Sbjct: 439 LAELRNQMAEP--PPPEPPAGPSEVEQQ-LQAEAEHLRKELEGLAGQLQAQVQDNEGLSR 495 Query: 317 ---QPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKR 373 + E + E EL R LE Q +R Q R + E+ Sbjct: 496 LNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSG 555 Query: 374 GAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMS---ETVRLVS 418 + ++ +IT L + + E+ +++ E++ +S ETV L S Sbjct: 556 FVKLTNENMEIT-SALQSEQHVKRELGKKLGELQEKLSELKETVELKS 602 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.136 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,788,033 Number of Sequences: 37866 Number of extensions: 998940 Number of successful extensions: 6950 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 52 Number of HSP's successfully gapped in prelim test: 290 Number of HSP's that attempted gapping in prelim test: 5745 Number of HSP's gapped (non-prelim): 1140 length of query: 510 length of database: 18,247,518 effective HSP length: 107 effective length of query: 403 effective length of database: 14,195,856 effective search space: 5720929968 effective search space used: 5720929968 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.