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Search of human proteins with 5031681
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
(561 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 1154 0.0
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s... 952 0.0
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 148 1e-35
gi|215422375 neural precursor cell expressed, developmentally do... 117 2e-26
gi|5453680 neural precursor cell expressed, developmentally down... 117 2e-26
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r... 115 1e-25
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r... 114 3e-25
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r... 113 4e-25
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r... 112 7e-25
gi|78486553 neural precursor cell expressed, developmentally dow... 101 2e-21
gi|55769585 HEF-like protein [Homo sapiens] 92 2e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni... 77 4e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 76 7e-14
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 2e-13
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 75 2e-13
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 75 2e-13
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 74 3e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 73 6e-13
gi|110832843 TBP-associated factor 4 [Homo sapiens] 72 1e-12
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 72 1e-12
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 72 1e-12
gi|54860079 nadrin isoform 1 [Homo sapiens] 72 2e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 71 2e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is... 71 3e-12
gi|150417989 cyclin K isoform 1 [Homo sapiens] 70 7e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 69 1e-11
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 67 6e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 67 6e-11
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 66 7e-11
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 65 2e-10
>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
Length = 561
Score = 1154 bits (2985), Expect = 0.0
Identities = 561/561 (100%), Positives = 561/561 (100%)
Query: 1 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA 60
MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA
Sbjct: 1 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA 60
Query: 61 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC 120
NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC
Sbjct: 61 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC 120
Query: 121 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP 180
PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP
Sbjct: 121 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP 180
Query: 181 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL 240
PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL
Sbjct: 181 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL 240
Query: 241 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE 300
ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE
Sbjct: 241 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE 300
Query: 301 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE 360
SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE
Sbjct: 301 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE 360
Query: 361 MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEAL 420
MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEAL
Sbjct: 361 MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEAL 420
Query: 421 SPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVA 480
SPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVA
Sbjct: 421 SPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVA 480
Query: 481 AHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQ 540
AHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQ
Sbjct: 481 AHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQ 540
Query: 541 CVTELAGQALQFTTLLTSLAP 561
CVTELAGQALQFTTLLTSLAP
Sbjct: 541 CVTELAGQALQFTTLLTSLAP 561
>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
sapiens]
Length = 468
Score = 952 bits (2462), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 100 VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 159
VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS
Sbjct: 7 VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 66
Query: 160 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 219
SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA
Sbjct: 67 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 126
Query: 220 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT 279
PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT
Sbjct: 127 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT 186
Query: 280 LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 339
LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP
Sbjct: 187 LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 246
Query: 340 PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD 399
PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD
Sbjct: 247 PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD 306
Query: 400 QACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMS 459
QACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMS
Sbjct: 307 QACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMS 366
Query: 460 STQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATV 519
STQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATV
Sbjct: 367 STQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATV 426
Query: 520 LAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP 561
LAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP
Sbjct: 427 LAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP 468
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 148 bits (373), Expect = 1e-35
Identities = 174/580 (30%), Positives = 235/580 (40%), Gaps = 117/580 (20%)
Query: 58 VPANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPA 117
VP K P PA P + A P P SP PA D VY VPPPA P PP
Sbjct: 329 VPPAFAKAKPFDPARTPLVLAAPP--PDSP-PAED-------VYDVPPPA-PDLYDVPP- 376
Query: 118 GPCPPSPDLIYKIPRASGTQLAAPRDALE-------VYDVPPTALR-VPSSGPYDCPASF 169
G P P +Y +PR + P + + VY VPP A R P+ G +S
Sbjct: 377 GLRRPGPGTLYDVPR----ERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASST 432
Query: 170 -----SHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEP----------DLEWEGG----- 209
S + + PG + P ++ + + A L+ DL G
Sbjct: 433 GSTRSSQSASSLEVAGPGRE--PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSW 490
Query: 210 REPGPPIYAAPSNLKRASALLNLYEAPEELL-----ADGEGGGTDEGIYDVPLLGPEAPP 264
R P P +L+ A A + A ELL A G T + L +
Sbjct: 491 RSPSEPQEPLVQDLQAAVAAVQ--SAVHELLEFARSAVGNAAHTSDRALHAKL-SRQLQK 547
Query: 265 SPEPPGALASHDQ-------------DTLAQLLARSPPPPHRPRL------PSAESLSRR 305
+ L +H Q + L +L+A S P + +A L RR
Sbjct: 548 MEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRR 607
Query: 306 PLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDP 365
P PE P+P + SIQ RPLP PP +D P
Sbjct: 608 TKATAPGPEGGGTLH-PNPTD-KTSSIQSRPLPSPPKFTS----------------QDSP 649
Query: 366 AGHHNEYEGIPMAEEYDYVHLKG---MDKAQGSRPPDQACT--GDPELPERGMP------ 414
G + EG M E+YDYVHL+G +K Q + T G +L + +
Sbjct: 650 DGQYENSEGGWM-EDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLE 708
Query: 415 --------------APQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSS 460
P + L+PG + D QLL FY QC+++ + L AV A ++
Sbjct: 709 QEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTA 768
Query: 461 TQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVL 520
NQPP++FV HSK V+++AH+LVF+GDTL R A +A +R+QV L LR V
Sbjct: 769 VATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVA 828
Query: 521 AVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 560
K AAL YPS A Q+MV+ V EL QF +L LA
Sbjct: 829 TTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLA 868
Score = 134 bits (336), Expect = 3e-31
Identities = 126/405 (31%), Positives = 172/405 (42%), Gaps = 88/405 (21%)
Query: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66
LA+ALYDN AESP ELSFR+GD++ VL+++ GLDGW LCSLHG+QGIVP NR+K+L
Sbjct: 7 LAKALYDNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPGNRLKILVG 65
Query: 67 -----PAGPAPKPSLSPASPAQPGSPYPAPDHSN-----------EDQEVYVVPPPAR-- 108
PAGP P P +PA P QPG PAP S + VY+VP P++
Sbjct: 66 MYDKKPAGPGPGPPATPAQP-QPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
Query: 109 ------PCPT---SGPPA------------GPCPPSPDLIYKIPRASGTQLAAPRDALEV 147
P P+ PPA P P +Y++P G A ++
Sbjct: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPG------GPAQDI 178
Query: 148 YDVPPTA------LRVPSSGPYDCPASFSHPLTRVAPQPPGE---------DDAPYDVP- 191
Y VPP+A +VP S P V P G+ + YD+P
Sbjct: 179 YQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPR 238
Query: 192 --LTPKPPAELE-PDLEWEGGREPGPPIYAAPSNLKRA----SALLNLYEAPEELLADGE 244
L P P + P + + G +Y P + LL +Y+ P + G
Sbjct: 239 HLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPS-VEKGL 297
Query: 245 GGGTDEGIYDV-PLLGPEAPPSP--------EPPGALASHDQDTLAQLLARSPPPPHRPR 295
+YDV P + + P P PP + D L + PPP
Sbjct: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDS-- 355
Query: 296 LPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSI-QDRPLPP 339
P AE + P PA + + P + P PG + ++R LPP
Sbjct: 356 -PPAEDVYDVPPPAPDLYDV--PPGLRRPGPGTLYDVPRERVLPP 397
Score = 55.8 bits (133), Expect = 1e-07
Identities = 52/172 (30%), Positives = 67/172 (38%), Gaps = 27/172 (15%)
Query: 94 SNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT 153
S QEVY PP A P P +Y +P + L P + VYDVPP+
Sbjct: 260 SQYGQEVYDTPPMAVKGPNGRDPLLE-------VYDVPPSVEKGLP-PSNHHAVYDVPPS 311
Query: 154 ALRVPSSGP------YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWE 207
+ GP YD P +F+ + P P P PPAE D+
Sbjct: 312 VSKDVPDGPLLREETYDVPPAFA----KAKPFDPARTPLVLAAPPPDSPPAEDVYDVP-- 365
Query: 208 GGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGE---GGGTDEGIYDVP 256
P P +Y P L+R LY+ P E + E GG D G+Y VP
Sbjct: 366 ---PPAPDLYDVPPGLRRPGPG-TLYDVPRERVLPPEVADGGVVDSGVYAVP 413
>gi|215422375 neural precursor cell expressed, developmentally
down-regulated 9 isoform 3 [Homo sapiens]
Length = 834
Score = 117 bits (294), Expect = 2e-26
Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)
Query: 356 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 400
P G E P ++ ++YDYVHL+G ++ Q +
Sbjct: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
Query: 401 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 451
+L E+ + P E P + L VS D QLL FY QC++H+ +L
Sbjct: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
Query: 452 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 511
A+ AL S + QPPR+FV HSK V+++AH+LVF+GDTL R + +R +V + L
Sbjct: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
Query: 512 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 560
+ L+ V+A K AAL YPS+ A+QEMV VT+L+ A F L +A
Sbjct: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
Score = 117 bits (293), Expect = 3e-26
Identities = 120/399 (30%), Positives = 157/399 (39%), Gaps = 110/399 (27%)
Query: 5 TSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVK 64
T +ARALYDN E +EL+FR+GD+L V++ + GGL+GW LCSLHG+QGIVP NRVK
Sbjct: 3 TRNLMARALYDNVPECAEELAFRKGDILTVIE-QNTGGLEGWWLCSLHGRQGIVPGNRVK 61
Query: 65 LLPAGPAPKPSLSPASPA--------------QPGSPYPAP------------------- 91
LL GP + + S PA Q +P AP
Sbjct: 62 LL-IGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQV 120
Query: 92 --DHSNEDQEVYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPR 142
H ++QEVY VPP + TSGP G P +Y+ P R
Sbjct: 121 PTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYP---------SR 171
Query: 143 DALEVYDVPPTALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKP 196
+VYD+PP+ + G YD P S FS P+ + PQ YD+P
Sbjct: 172 YQKDVYDIPPSH---TTQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP----- 217
Query: 197 PAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYD 254
P +YA P + R A L Y+ P + G EG+YD
Sbjct: 218 ---------------PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYD 262
Query: 255 VPLLGPEAPPSPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPL 307
+P P +P G + D A+ +AR S P H P P
Sbjct: 263 IP------PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQN 314
Query: 308 PALPVPEA-----PSPSPVPSPAPGRKGSIQDRPLPPPP 341
A VP P P + + D PL PP
Sbjct: 315 DAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPP 353
>gi|5453680 neural precursor cell expressed, developmentally
down-regulated 9 isoform 1 [Homo sapiens]
Length = 834
Score = 117 bits (294), Expect = 2e-26
Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)
Query: 356 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 400
P G E P ++ ++YDYVHL+G ++ Q +
Sbjct: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
Query: 401 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 451
+L E+ + P E P + L VS D QLL FY QC++H+ +L
Sbjct: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
Query: 452 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 511
A+ AL S + QPPR+FV HSK V+++AH+LVF+GDTL R + +R +V + L
Sbjct: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
Query: 512 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 560
+ L+ V+A K AAL YPS+ A+QEMV VT+L+ A F L +A
Sbjct: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
Score = 116 bits (291), Expect = 5e-26
Identities = 119/395 (30%), Positives = 156/395 (39%), Gaps = 110/395 (27%)
Query: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPA 68
+ARALYDN E +EL+FR+GD+L V++ + GGL+GW LCSLHG+QGIVP NRVKLL
Sbjct: 7 MARALYDNVPECAEELAFRKGDILTVIE-QNTGGLEGWWLCSLHGRQGIVPGNRVKLL-I 64
Query: 69 GPAPKPSLSPASPA--------------QPGSPYPAP---------------------DH 93
GP + + S PA Q +P AP H
Sbjct: 65 GPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPSYQNQGIYQVPTGH 124
Query: 94 SNEDQEVYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPRDALE 146
++QEVY VPP + TSGP G P +Y+ P R +
Sbjct: 125 GTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYP---------SRYQKD 175
Query: 147 VYDVPPTALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAEL 200
VYD+PP+ + G YD P S FS P+ + PQ YD+P
Sbjct: 176 VYDIPPSH---TTQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP--------- 217
Query: 201 EPDLEWEGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYDVPLL 258
P +YA P + R A L Y+ P + G EG+YD+P
Sbjct: 218 -----------PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDIP-- 264
Query: 259 GPEAPPSPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPLPALP 311
P +P G + D A+ +AR S P H P P A
Sbjct: 265 ----PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQNDAYD 318
Query: 312 VPEA-----PSPSPVPSPAPGRKGSIQDRPLPPPP 341
VP P P + + D PL PP
Sbjct: 319 VPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPP 353
>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 353
Score = 115 bits (288), Expect = 1e-25
Identities = 110/336 (32%), Positives = 140/336 (41%), Gaps = 61/336 (18%)
Query: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66
LA+ALYDN AESP ELSFR+GD++ VL+++ GLDGW LCSLHG+QGI+P N +K+L
Sbjct: 7 LAKALYDNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIMPGNHLKILVG 65
Query: 67 -----PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCP 121
PAGP P P PA+PAQP AP VPP ++ P
Sbjct: 66 MYDKKPAGPGPGP---PATPAQPQPGLHAP-----------VPPASQYTPML---PNTYQ 108
Query: 122 PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP 181
P PD +Y +P S Q +Y VP PS PA + ++ P P
Sbjct: 109 PQPDSVYLVPTPSKAQQG-------LYQVPG-----PSPQFQSPPAKQTSTFSKQTPHHP 156
Query: 182 GEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS-------ALLNLYE 234
A ++P P + + G IY PS++ S A
Sbjct: 157 FPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVS 216
Query: 235 APEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASH-------DQDTLAQLLARS 287
+P L G G + IY P AP EP AL H Q T + S
Sbjct: 217 SPRCLPPRGLGSPSFLLIYLSP-----APARGEPCRALTGHLSQRHWAPQVTEQVQPSLS 271
Query: 288 PPPPHRPRLPSAESLSRR-----PLPALPVPEAPSP 318
P R P S R A+ PEA SP
Sbjct: 272 TAPGDRAVFPQLCSSGRTLRIHVEKEAVTTPEASSP 307
Score = 29.6 bits (65), Expect = 7.7
Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 68/220 (30%)
Query: 251 GIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 310
G+YD GP P P A+ P H P P+++ P
Sbjct: 65 GMYDKKPAGPGPGPPATP----------------AQPQPGLHAPVPPASQYTPMLPNTYQ 108
Query: 311 PVPEA----PSPS---------PVPSP----APGRKGSIQDR-----PLPPPPPRL---- 344
P P++ P+PS P PSP P ++ S + P P P L
Sbjct: 109 PQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVS 168
Query: 345 PGYGGPKVEGDPEGREMEDDP--AGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQ-A 401
PG GGP +++ P AG ++ +P + + +G++PP + A
Sbjct: 169 PGPGGP-------AQDIYQVPPSAGMGHDIYQVPSSMD--------TRSWEGTKPPAKCA 213
Query: 402 CTGDPE-LPERGMPAPQEA---LSP----GEPLVVSTGDL 433
P LP RG+ +P LSP GEP TG L
Sbjct: 214 SVSSPRCLPPRGLGSPSFLLIYLSPAPARGEPCRALTGHL 253
>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 232
Score = 114 bits (284), Expect = 3e-25
Identities = 90/239 (37%), Positives = 114/239 (47%), Gaps = 52/239 (21%)
Query: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66
LA+ALY N AESP ELSFR+GD++ VL+++ GLDGW LCSLHG+QGIVP N +K+L
Sbjct: 7 LAKALYVNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
Query: 67 -----PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCP 121
PAGP P P PA+PAQP AP VPP ++ P
Sbjct: 66 MYDKKPAGPGPGP---PATPAQPQPGLHAP-----------VPPASQYTPML---PNTYQ 108
Query: 122 PSPDLIYKIPRASGTQ--LAAPRDALEVYDVPP-----TALRVPSSGPYDCPASFSHPLT 174
P PD +Y +P S Q L + PP T + P+ PA+ L
Sbjct: 109 PQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPAT---DLY 165
Query: 175 RVAPQPPGEDDAPYDVPLTPKPPAELEPDL----------EWEGGREPGPPIYAAPSNL 223
+V+P P G Y VP P A + D+ WEG + PP A PS L
Sbjct: 166 QVSPGPGGPAQDIYQVP----PSAGMGHDIYQVPSSMDTRSWEGTK---PPAKANPSPL 217
>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 224
Score = 113 bits (283), Expect = 4e-25
Identities = 84/231 (36%), Positives = 110/231 (47%), Gaps = 42/231 (18%)
Query: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66
LA+ALY N AESP ELSFR+GD++ VL+++ GLDGW LCSLHG+QGIVP N +K+L
Sbjct: 7 LAKALYVNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
Query: 67 -----PAGPAPKPSLSPASPAQPGSPYPAPDHSN-----------EDQEVYVVPPPARPC 110
PAGP P P +PA P QPG P P S + VY+VP P++
Sbjct: 66 MYDKKPAGPGPGPPATPAQP-QPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
Query: 111 PTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP-------Y 163
GP P ++ P A T + + + P T L S GP Y
Sbjct: 125 QGLYQVPGPSPQ-----FQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIY 179
Query: 164 DCP--ASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREP 212
P A H + +V P D ++ KPPA++ L W P
Sbjct: 180 QVPPSAGMGHDIYQV---PSSMDTRSWE---GTKPPAKVR--LSWHSRAAP 222
>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 368
Score = 112 bits (281), Expect = 7e-25
Identities = 96/281 (34%), Positives = 123/281 (43%), Gaps = 49/281 (17%)
Query: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66
LA+ALY N AESP ELSFR+GD++ VL+++ GLDGW LCSLHG+QGIVP N +K+L
Sbjct: 7 LAKALYVNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
Query: 67 -----PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCP 121
PAGP P P PA+PAQP AP VPP ++ P
Sbjct: 66 MYDKKPAGPGPGP---PATPAQPQPGLHAP-----------VPPASQYTPML---PNTYQ 108
Query: 122 PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP 181
P PD +Y +P S Q +Y VP PS PA + ++ P P
Sbjct: 109 PQPDSVYLVPTPSKAQQG-------LYQVPG-----PSPQFQSPPAKQTSTFSKQTPHHP 156
Query: 182 GEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS-------ALLNLYE 234
A ++P P + + G IY PS++ S A
Sbjct: 157 FPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVS 216
Query: 235 APEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASH 275
+P L G G + IY P AP EP AL H
Sbjct: 217 SPRCLPPRGLGSPSFLLIYLSP-----APARGEPCRALTGH 252
Score = 31.6 bits (70), Expect = 2.0
Identities = 58/232 (25%), Positives = 85/232 (36%), Gaps = 68/232 (29%)
Query: 251 GIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 310
G+YD GP P P A+ P H P P+++ P
Sbjct: 65 GMYDKKPAGPGPGPPATP----------------AQPQPGLHAPVPPASQYTPMLPNTYQ 108
Query: 311 PVPEA----PSPS---------PVPSP----APGRKGSIQDR-----PLPPPPPRL---- 344
P P++ P+PS P PSP P ++ S + P P P L
Sbjct: 109 PQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVS 168
Query: 345 PGYGGPKVEGDPEGREMEDDP--AGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQ-A 401
PG GGP +++ P AG ++ +P + + +G++PP + A
Sbjct: 169 PGPGGP-------AQDIYQVPPSAGMGHDIYQVPSSMD--------TRSWEGTKPPAKCA 213
Query: 402 CTGDPE-LPERGMPAPQEA---LSP----GEPLVVSTGDLQLLYFYAGQCQS 445
P LP RG+ +P LSP GEP TG L ++ C S
Sbjct: 214 SVSSPRCLPPRGLGSPSFLLIYLSPAPARGEPCRALTGHLSQRHWAPQLCSS 265
>gi|78486553 neural precursor cell expressed, developmentally
down-regulated 9 isoform 2 [Homo sapiens]
Length = 174
Score = 101 bits (251), Expect = 2e-21
Identities = 70/160 (43%), Positives = 90/160 (56%), Gaps = 22/160 (13%)
Query: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPA 68
+ARALYDN E +EL+FR+GD+L V++ + GGL+GW LCSLHG+QGIVP NRVKLL
Sbjct: 7 MARALYDNVPECAEELAFRKGDILTVIE-QNTGGLEGWWLCSLHGRQGIVPGNRVKLL-I 64
Query: 69 GPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVP-PPARPCPTSGPPAGPCPPS--PD 125
GP + + S PA + Q++Y VP P A P T PPS
Sbjct: 65 GPMQETASSHEQPAS-----GLMQQTFGQQKLYQVPNPQAAPRDT----IYQVPPSYQNQ 115
Query: 126 LIYKIPRASGTQLAAPRDALEVYDVPPTALRV--PSSGPY 163
IY++P GTQ EVY VPP+ R +SGP+
Sbjct: 116 GIYQVPTGHGTQ------EQEVYQVPPSVQRSIGGTSGPH 149
>gi|55769585 HEF-like protein [Homo sapiens]
Length = 786
Score = 91.7 bits (226), Expect = 2e-18
Identities = 101/341 (29%), Positives = 143/341 (41%), Gaps = 60/341 (17%)
Query: 1 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA 60
M A LARALYDN + EL+F RGD+L +L++ +GW C LHG+QG+ PA
Sbjct: 7 MDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPES-EGWWKCLLHGRQGLAPA 65
Query: 61 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGP----- 115
NR+++L A +P P AP S E +V +P P PT GP
Sbjct: 66 NRLQILTEVAADRP-----CPPFLRGLEEAPASSEETYQVPTLPRP----PTPGPVYEQM 116
Query: 116 ---PAGPCPPSPDLIYKIPRASGT-------QLAAPRDALEVYDVPPTA-LRVPSSGPYD 164
GP PP+ +Y+ P + L+ P+ A+ P A L S YD
Sbjct: 117 RSWAEGPQPPTAQ-VYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYD 175
Query: 165 CPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLK 224
P P+ P E YD+P +PK PD + G G P+ + + L+
Sbjct: 176 VPTQHRGPVVLKEP----EKQQLYDIPASPKKAGLHPPDSQASG---QGVPLISV-TTLR 227
Query: 225 RA--SALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 282
R S L N P++ E IYD P+ +A P L S +++
Sbjct: 228 RGGYSTLPN----PQK----------SEWIYDTPVSPGKASVRNTP---LTSFAEESRPH 270
Query: 283 LLARSP-----PPPHRPRLPSAESLSRRPL-PALPVPEAPS 317
L S PP R R + + + P+ L +PE PS
Sbjct: 271 ALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPS 311
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Query: 443 CQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRA 502
C+ ++ AL A++A S ++QP + + SK V++ +LV DTL +R
Sbjct: 676 CRLYFGALFKAISAFHGSLSSSQPAEI-ITQSKLVIMVGQKLV---DTLCMETQERDVRN 731
Query: 503 QVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQF 552
++ + L L+ LA K A L YPS A+ + +L QF
Sbjct: 732 EILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQF 781
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 77.0 bits (188), Expect = 4e-14
Identities = 101/397 (25%), Positives = 138/397 (34%), Gaps = 49/397 (12%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG 118
PA L G A P +PA P P + + PP A P G P
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Query: 119 P-----------CPPSPDLIYKIPRASGTQLAAP-RDALEVYDVPPTALRVPSSGPYDCP 166
P PPSP +P + + P + + PP A GP P
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386
Query: 167 ASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPG----PPIYAAPSN 222
S P P G+ +P +PL+PK A P + EG P P P +
Sbjct: 1387 PSPKR--GPAIPSPKGDPTSPAVIPLSPK-KAPATP-VTREGAATPSKGDLTPPAVTPVS 1442
Query: 223 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 282
LK+A A AP +GG P L PPSP+ P A + +
Sbjct: 1443 LKKAPAT----SAP-------KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Query: 283 LLARSPPPPHRPRLPSAESLSRRPLPALPV----PEAPSPSPVPSPAPG----RKGSIQD 334
+P P P LP+ S + +PA P P AP+ + + P ++ I
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 335 RPLPPPPPRLPGYGGPK-VEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQ 393
P P + P PK P +E PA + Y+G P +E + A
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL------LIPPAV 1605
Query: 394 GSRPPDQACTG---DPELPERGMPAPQEALSPGEPLV 427
S P +A T P PE+G P +P P V
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV 1642
Score = 68.2 bits (165), Expect = 2e-11
Identities = 94/375 (25%), Positives = 126/375 (33%), Gaps = 46/375 (12%)
Query: 64 KLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCP-- 121
K +PA P+PK + +P + A P SP P + + PP A P G PA P P
Sbjct: 928 KGIPASPSPKGAPTPPA-ATPPSPKGGP--ATPSPKWAPTPPAATPPSPKGGPATPSPKG 984
Query: 122 -PSPDLIYKIPRASGTQLAAPRDALEVYDV-PPTALRVPSSGPYDCPASFSHPLTRVAPQ 179
P+P G +P+ A V PP+ P++ P+ AS T A
Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS-----TPPAAT 1039
Query: 180 PPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEEL 239
PP +P PL P L G P + AP+ P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT-------------PPAAT 1086
Query: 240 LADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPH------- 292
+GG P+ P A P P G LA+ A +PP P
Sbjct: 1087 PPSPKGGPATPSPKGAPM--PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 293 ---RPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGG 349
P P+A S + A P P+ +P +P P KG + P P P P
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKGGLA-TPSPKGAPTTPAATP 1202
Query: 350 PKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYV--HLKGMDKAQGSRPPDQACTGDPE 407
P P+G P G P + + KG + PP G
Sbjct: 1203 P----SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK-GGPAT 1257
Query: 408 LPERGMPAPQEALSP 422
P +G P P A P
Sbjct: 1258 PPPKGAPTPPAATPP 1272
Score = 58.5 bits (140), Expect = 2e-08
Identities = 102/426 (23%), Positives = 152/426 (35%), Gaps = 87/426 (20%)
Query: 67 PAGPAPKPS------LSPASPAQPGSPYPAPDHSNEDQEVY----VVPPPARPCPTSGPP 116
PAG AP + + ASP G+ AP + + +VP + CP + P
Sbjct: 655 PAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP 714
Query: 117 AGPCPP------SPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVP-SSGPYDCP--- 166
C P +P++ +P S P +V + T+ P +S P +CP
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED 774
Query: 167 ------ASFSHPLTRVA--PQPPGEDDAPY-------------DVPL----TPKPPAEL- 200
AS LT +A P P G +P D P+ +P P E
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834
Query: 201 ---EPDLEWEGGRE-------PGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDE 250
E L ++G ++ P PP +P SA+ L +P+ + + T
Sbjct: 835 FLPENSLSFQGSKDSPATTHSPTPP---SPKGAPTPSAVTPL--SPKGVTLPPKETPTPS 889
Query: 251 GI-YDVPLLGPEAPPSPEPPGALASHDQDTLAQL------LARSPPPPHRPRLPSAESLS 303
+ P GP P + P + A+ + SP P P P+A S
Sbjct: 890 VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
Query: 304 RRPLPALPVPE-APSPSPVPSPAP-GRKGSIQDRPLPPPPPRLP--GYGGPKVEGDPEGR 359
+ PA P P+ AP+P P+P G + + P PP P GGP P +
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP---ATPSPK 1006
Query: 360 EMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPP----DQACT----GDPELPER 411
PA +G P A + KG + PP A T G P P
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFP----KGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Query: 412 GMPAPQ 417
+P+P+
Sbjct: 1063 TLPSPK 1068
Score = 58.5 bits (140), Expect = 2e-08
Identities = 110/411 (26%), Positives = 140/411 (34%), Gaps = 85/411 (20%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPP-----PARPCPTSGP-PAGPC 120
PA P P PA+P+ G+P P PP PA P P P P
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPA----------ATPPSPKGGPATPSPKGAPTPPAVT 1015
Query: 121 PPSPD---LIYKIPRASGTQLAA----PRDALEVYDVPPTALRVPSS---GPYDCPASFS 170
PPSP P+ + T AA P+ + +P A P++ P PA+
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT-- 1073
Query: 171 HPLTRVAPQPPGEDD-APYDVPLTPKP------PAELEPDLEWEGGREP--GPPIY--AA 219
P + AP PP +P P TP P PA P + P G P A
Sbjct: 1074 -PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132
Query: 220 PSNLKRASALLNLYEAPEELLA---DGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHD 276
P + K A AP A +GG P PPSP+ G LA+
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK--GGLATPS 1190
Query: 277 QDTLAQLLARSPPPPH----------RPRLPSAESLSRR-------PLPALPVPEAPSPS 319
A +PP P P P+A S + P A P A PS
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Query: 320 PVPSPA-PGRKGSIQDRPLPP---PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGI 375
P PA P KG+ P PP PP G P +G P + P+
Sbjct: 1251 PKGGPATPPPKGA----PTPPAATPPSLKGGLATPPHKGAP-NPAVVTPPSPKGGPATSP 1305
Query: 376 PMAEEYDYVHLKGMDKAQGSRPPD-QACTGDPELPERGMPAPQEALSPGEP 425
P KG + PP + G P P +G P P A++P P
Sbjct: 1306 P----------KGAPTPPAATPPSPKGSPGTP--PPKGAPTP-PAVTPPSP 1343
Score = 56.6 bits (135), Expect = 6e-08
Identities = 78/318 (24%), Positives = 107/318 (33%), Gaps = 75/318 (23%)
Query: 54 QQGIVPANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPT- 112
+ +P N + + +P + SP P+ G+P P+ + V +PP P P+
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV-TLPPKETPTPSV 890
Query: 113 ---SGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASF 169
P GP P+P + P S T + P A P+ P PAS
Sbjct: 891 VNLPFPKEGPATPAPK---QAPALSMTSSS-----------PKKARATPA--PKGIPAS- 933
Query: 170 SHPLTRVAPQPPGEDD-APYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASA 228
P + AP PP +P P TP P +W P PP PS
Sbjct: 934 --PSPKGAPTPPAATPPSPKGGPATPSP--------KWA----PTPPAATPPSP------ 973
Query: 229 LLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSP 288
+GG P PPSP+ A +P
Sbjct: 974 ---------------KGGPATPSPKGAPTPPAATPPSPKGGPA---------------TP 1003
Query: 289 PPPHRPRLPSAESLSRRPLPAL-PVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGY 347
P P P+ S + PA P P+ S P +P P KGS PLP P P
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPAA 1062
Query: 348 GGPKVEGDPEGREMEDDP 365
P +G P ++ P
Sbjct: 1063 TLPSPKGGPATPSLKGAP 1080
Score = 56.6 bits (135), Expect = 6e-08
Identities = 95/388 (24%), Positives = 122/388 (31%), Gaps = 97/388 (25%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG 118
P PA P P A+P+ G+P P + + + P + PT+ P A
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGLATPSPKGAPTT-PAAT 1224
Query: 119 PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAP 178
P P L P+ + T AA PP+ P GP P
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAA---------TPPS----PKGGP-------------ATP 1258
Query: 179 QPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEE 238
P G P PPA P L+ G PP AP+ P
Sbjct: 1259 PPKG----------APTPPAATPPSLK---GGLATPPHKGAPN--------------PAV 1291
Query: 239 LLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPS 298
+ GG P G PP+ PP S +PPP P P+
Sbjct: 1292 VTPPSPKGGPATS----PPKGAPTPPAATPPSPKGS----------PGTPPPKGAPTPPA 1337
Query: 299 AESLSRRPLPALPV--------PEAPSPSPVPSP---APGRKGSIQDRPLPPPPPRLPGY 347
S + P LP P PS P+P P KG PP P R P
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG--PAMTPPSPKRGPAI 1395
Query: 348 GGPKVEGDPEGREM-----EDDPA------GHHNEYEGIPMAEEYDYVHLKGMDKAQGSR 396
PK GDP + + PA G +G V LK +
Sbjct: 1396 PSPK--GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
Query: 397 --PPDQACTGDPELPERGMPAPQEALSP 422
P + GDP LP P+P+E +P
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Score = 50.8 bits (120), Expect = 3e-06
Identities = 70/292 (23%), Positives = 98/292 (33%), Gaps = 29/292 (9%)
Query: 64 KLLPAGPAPKPSLSPASPAQPGSPYPAPDHSN-----EDQEVYVVPPPARPCPTSGP-PA 117
K PA P PK + + S + SP PA S +E+ + P P P P P
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Query: 118 GPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVA 177
PPSP+ P GT + P + D P + V P + +
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677
Query: 178 PQPPGE---DDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYE 234
P E AP P+ P + + + PPI PS + L+
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRK---GPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734
Query: 235 APEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRP 294
L + T +G +A SP+ P A T A P
Sbjct: 1735 PAPLLPVQKDSSKTAKG--------KDASHSPKGPLAPPESKASTPLTAAAFEKVLPK-- 1784
Query: 295 RLPSAESLSRRPLPALPVPEAPSPSPVPSP----APGRKGSIQDRPLPPPPP 342
P + S+S P P + +P APSP P P P G + + P P P
Sbjct: 1785 --PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/295 (23%), Positives = 96/295 (32%), Gaps = 53/295 (17%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDL 126
PA P P PA+PA G+P PP P P P + +
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTP---------------TSPPVTPSSLKDSPTSPASVTCKM 1661
Query: 127 IYKIPRAS-GTQLAAPRDALEVYDVPPTALRVP------SSGPYDCPASFSHPLTRVAPQ 179
+P+AS G AL+ V P P GP +S + P + P
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP--PICPD 1719
Query: 180 PPGEDDAPYDVPLTPKPPAELEPDLE--------WEGGREPGPPIYAAPSNLKRASALLN 231
P ++ + PL+ PA L P + + P P+ AP K ++ L
Sbjct: 1720 PSAKNGSKG--PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL--APPESKASTPLTA 1775
Query: 232 LYEAPEELLADGEGGGTDEGIYD----------VPLLGPEAPPSPEPPGALASHDQDTLA 281
A E++L E VP L P+ P PG + LA
Sbjct: 1776 A--AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833
Query: 282 -----QLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGS 331
+LL PP P +P L P P P+PS KGS
Sbjct: 1834 PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGS 1888
Score = 38.9 bits (89), Expect = 0.013
Identities = 81/323 (25%), Positives = 112/323 (34%), Gaps = 49/323 (15%)
Query: 66 LPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPD 125
LP +P P P S A SP+P+P S VP P T+ P G P +P
Sbjct: 45 LPPPCSPAPQQCPLSAANQASPFPSP--STIASTPLEVPFPQSSSGTA-LPLGTAPEAPT 101
Query: 126 LIYKIPRASGTQLAAPRDALEVYDVPPTALRVP-SSGPYDCPASFSHPLTRVAPQPPGED 184
+P G ++ AL + PT P SS P A H + + + PP
Sbjct: 102 F---LPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL 158
Query: 185 DAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGE 244
+P V + E G APS K NL + P E++ + +
Sbjct: 159 TSPPSVAVA-------------ESGSVITLSAPIAPSEPK-----TNLNKVPSEVVPNPK 200
Query: 245 GGGTDEGIYD-VPL----------LGPEAPPSPEPPGALA---SHDQDTLAQLLARSPPP 290
G + I VP G + P P LA +DT + SP
Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN 260
Query: 291 PHRPRL------PSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP---P 341
P L P+A SLS + LP + + + P P GS PL
Sbjct: 261 PGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGS-HLAPLHQSSFGS 319
Query: 342 PRLPGYGGPKVEGDPEGREMEDD 364
+L G GP DP + + D
Sbjct: 320 VQLLGQTGPSALSDPTVKTISVD 342
Score = 33.1 bits (74), Expect = 0.69
Identities = 64/283 (22%), Positives = 102/283 (36%), Gaps = 33/283 (11%)
Query: 50 SLHGQQGIVPA--NRVKLLPAGPAPKPSLSPA---SPAQPGSPYPAPDHSNEDQEVYVVP 104
S Q+ ++P +R +++PA A P ++P+ P+ S +P S + +
Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408
Query: 105 PPARPCPTSGPPAGPCPPSPDLIYKIPRAS-GTQLAAPRDALEVYDVPPTALRVPSSGPY 163
P S P A P L+ ++P +S GT + + P T V +
Sbjct: 409 PTTSLILKSSPNATYHYP---LVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVS- 464
Query: 164 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPA-ELEPDLEWEGGREPGPPIYAAPSN 222
P S P++ + P P A P+ PK P+ ++ L R P P P +
Sbjct: 465 --PPMSSGPISNIEPTSPA---ALVMAPVAPKEPSTQVATTL-----RIPVSPPLPDPED 514
Query: 223 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 282
LK + + L + P T + + VP AP SP G D L
Sbjct: 515 LKNLPSSV-LVKFP-----------TQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPL 562
Query: 283 LLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPA 325
+ A P S+ + P L P P+ PA
Sbjct: 563 VQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPA 605
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 76.3 bits (186), Expect = 7e-14
Identities = 107/394 (27%), Positives = 139/394 (35%), Gaps = 71/394 (18%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGP-CPPSPD 125
P P P LSP + P +P + + P A P P + PP P PSP
Sbjct: 602 PLQGLPSPPLSPLATPPPQAP----------PXLALPPLQAPPSPPASPPLSPLATPSP- 650
Query: 126 LIYKIPRASGTQLAA------PRDALEVYDVPPTALRVPSSG--PYDCPASFSHPLTRVA 177
+ P A L P ++ PP + V S P P S + P +V
Sbjct: 651 ---QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 178 PQPPGEDD-APYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAP 236
P PP +P P PP P L+ PP+ + + R LL AP
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL---AAP 764
Query: 237 EELLADGEGGGTDEGIYDVPLLGPEAPPS---------PEPPGALASHDQDTLAQLLARS 287
+ P P+APP+ P PP + + + L S
Sbjct: 765 PLQVPPSPPASLPMSPLAKP--PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Query: 288 P---PPPHRPRLPSAESLSRRPLP-ALPVPEAPSPSPVPSP---APGRKGSIQDRPLPPP 340
P PPP P + +A L P P A P +AP P P P G + ++ P PPP
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
Query: 341 PPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK-----AQGS 395
PP P D AGH + P EE L+G D A S
Sbjct: 883 PP----------SRSPSSTLSGPDLAGHSSSATSTP--EE-----LRGYDSGPEGGAAAS 925
Query: 396 RPPD-QACTGDPELPERGMPAPQEAL--SPGEPL 426
PPD + P RG PAP A +PG PL
Sbjct: 926 PPPDAELAACHPAAWSRG-PAPPLAFRGAPGAPL 958
Score = 63.9 bits (154), Expect = 4e-10
Identities = 86/322 (26%), Positives = 121/322 (37%), Gaps = 58/322 (18%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG 118
P N LPA P P L+ P P SP P + +P P P+ PP+
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPSAPP-------SLQTLPSPPATPPSQAPPSM 372
Query: 119 PCPP--SPDLIYKIP------RASGTQLAAPRDALEVYDV-PPTALRVP---------SS 160
PP +P + IP + L AP L + + T+L P +
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
Query: 161 GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAP 220
P AS + P +R A PP D P PL+ L+ L P ++P
Sbjct: 433 SPRQTQASLTSP-SRPASTPP--DSPPLQAPLSLPASPPLQTSL------SPAVSPLSSP 483
Query: 221 SNLKRASALLNL-YEAPEELLADGEGGGTDEGIYDVPLLGPE---APPSPE-PPGALASH 275
+ AL +L +P+ L+ +P L + APPS + PP +L +
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSS----------LIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 276 DQDTLAQLLARSPPPPHRPRLP-SAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQD 334
+ L L +PPP P + L P PA P P PSP+ +P P SI
Sbjct: 534 PLENLPSL---APPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLTTPPPETPSSI-- 587
Query: 335 RPLPPPPPRLPGYGGPKVEGDP 356
PPP P P ++G P
Sbjct: 588 --ATPPPQAPPALASPPLQGLP 607
Score = 60.5 bits (145), Expect = 4e-09
Identities = 69/285 (24%), Positives = 103/285 (36%), Gaps = 47/285 (16%)
Query: 74 PSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG---PCPPSPDLIYKI 130
PSL+P +P P PP PCP PP+ P P +P I
Sbjct: 539 PSLAPPPLQTASAPLTTPHLET--------PPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
Query: 131 PRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDD-APYD 189
P + LA+P + +P L ++ P P + P + P PP +P
Sbjct: 591 PPQAPPALASP----PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646
Query: 190 VPLTPKPPAELEPDLEWEGGREPGPPI---YAAPSNLKRASALLNLYEAPEELLADGEGG 246
P P A L+ P PP+ ++ P++ + + +AP L A
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP---- 702
Query: 247 GTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRL------PSAE 300
PL P +PP+ P A+ ++PPP P L P++
Sbjct: 703 ---------PLQVPPSPPASPPMSPSATPPP--------QAPPPLAAPPLQVPPSPPASP 745
Query: 301 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLP 345
+S P VP + P+ P P S+ PL PPP+ P
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAP 789
Score = 55.5 bits (132), Expect = 1e-07
Identities = 83/319 (26%), Positives = 113/319 (35%), Gaps = 62/319 (19%)
Query: 66 LPAGPAPKPSLSPA-SP-AQPGSPYPAP------DHSNEDQEVYVVPPPARPCPTSGPPA 117
LPA P + SLSPA SP + P + +P HS + ++ PP + PP+
Sbjct: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS 522
Query: 118 GPCPPS----------PDLIYKIPRASGTQLAAPRDALEV--------YDVPPTALRVP- 158
PP+ P L + + L P LE PP+ L P
Sbjct: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH--LETPPCPAPCPLQAPPSPLTTPP 580
Query: 159 -------SSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGRE 211
++ P P + + P + P PP +P P PP P L+
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPL---SPLATPPPQAPPXLALPPLQAPPSPP 637
Query: 212 PGPPI--YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPP 269
PP+ A PS + ++L +AP P+ P +PP+ P
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP------------PVQAPFSPPASPPV 685
Query: 270 GALASHDQDTLAQLLARSPP---PPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAP 326
A+ L A PP PP P P S S P P P P A P VP P
Sbjct: 686 SPSATPPSQAPPSLAA--PPLQVPPSPPASPPM-SPSATPPPQAPPPLAAPPLQVP---P 739
Query: 327 GRKGSIQDRPLPPPPPRLP 345
S P PPPR+P
Sbjct: 740 SPPASPPMSPSATPPPRVP 758
Score = 52.0 bits (123), Expect = 1e-06
Identities = 84/302 (27%), Positives = 105/302 (34%), Gaps = 49/302 (16%)
Query: 67 PAGPAPKPSLSP---------ASPAQ-PGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPP 116
PA P PS +P A P Q P SP +P S VPP P PP
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 117 AGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFS-HPLTR 175
+ P + K P + LA P L+ PP + P P+ AS PL
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATP--PLQALPSPPASF--PGQAPFSPSASLPMSPLAT 826
Query: 176 VAPQPPGEDDAPYDVPLTPKPPAELE-----------PDLEWEGGR-------EPGPPIY 217
PQ P AP + + P PPA PD G R P PP
Sbjct: 827 PPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885
Query: 218 AAPSNLKRASALL----NLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALA 273
+PS+ L + PEEL G G + G P P+A + P A +
Sbjct: 886 RSPSSTLSGPDLAGHSSSATSTPEELR--GYDSGPEGGAAASP--PPDAELAACHPAAWS 941
Query: 274 SHDQDTLAQLLARSPPPPHRPRLP--SAESL-----SRRPLPALPVPEAPSPSPVPSPAP 326
LA A P P P SA+ L + P A P P A P P P +
Sbjct: 942 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 1001
Query: 327 GR 328
G+
Sbjct: 1002 GK 1003
Score = 48.1 bits (113), Expect = 2e-05
Identities = 67/247 (27%), Positives = 84/247 (34%), Gaps = 54/247 (21%)
Query: 112 TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSH 171
TSGP G PSP + + RA+GT++ PR A P R P+ GP +S S
Sbjct: 164 TSGPTPGT--PSPAMARR-SRAAGTEVGLPRPA------PSARPRPPTEGPRKSVSSASE 214
Query: 172 -------PLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGR-EPGPPIYAAPSNL 223
P R P G P L+ P R P P + +
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 224 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPP---SPEPPGALASHDQDTL 280
K AL P A P LGP + +P P G A
Sbjct: 275 KGLQALRPPQVTPPRKDA-------------APALGPLSSSPLATPSPSGTKA------- 314
Query: 281 AQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP- 339
R PPP P +L P A P+P AP P+P S+Q P PP
Sbjct: 315 -----RPVPPPDNAATPLPATLPPSPPLATPLPLAP-------PSPSAPPSLQTLPSPPA 362
Query: 340 -PPPRLP 345
PP + P
Sbjct: 363 TPPSQAP 369
Score = 36.6 bits (83), Expect = 0.063
Identities = 41/141 (29%), Positives = 52/141 (36%), Gaps = 11/141 (7%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG 118
P LL P+P S + +P +P P P PD S + + P P P S P+
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRP--PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890
Query: 119 PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLT-RVA 177
PDL A+ T + L YD P +S P D + HP
Sbjct: 891 TL-SGPDLAGHSSSATSTP-----EELRGYDSGPEG-GAAASPPPDAELAACHPAAWSRG 943
Query: 178 PQPPGEDDAPYDVPLTPKPPA 198
P PP PL P PPA
Sbjct: 944 PAPPLAFRGAPGAPL-PWPPA 963
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 75.1 bits (183), Expect = 2e-13
Identities = 114/408 (27%), Positives = 143/408 (35%), Gaps = 94/408 (23%)
Query: 60 ANRVKLLPAGPAPKPSLS--PASPAQP--------GSPYPAPDHSNEDQEVYVVPPPARP 109
A + L P P+ PSL P+ PA P GSP HS ++ PP P
Sbjct: 335 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS------FLPSPPLSP 388
Query: 110 CPTSGPPAGPC--------PPSPDLIYKIPRASGTQLAAPRDALEV------YDVPPTAL 155
T P A P PPSP + + AP +AL V + PP+
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP-NALAVHLLQAPFSPPPSP- 446
Query: 156 RVPSSGPYDCPAS--FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPG 213
P P+ PAS S T + PP P VP P PPA +
Sbjct: 447 --PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATPPPQAP 502
Query: 214 PPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALA 273
PP+ A P L + +AP L P P PP +
Sbjct: 503 PPLAAPPLQLAKPPP-----QAPPALAT------------------PPLQALPSPPASFP 539
Query: 274 SHDQDTLAQLLARSP---PPPHRPRLPSAESLSRRPLP-ALPVPEAPSPSPVPSP---AP 326
+ + L SP PPP P + +A L P P A P +AP P P P
Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 327 GRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHL 386
G + ++ P PPPPP P D AGH + P EE L
Sbjct: 600 GPRLTLALAPGPPPPP----------SRSPSSTLSGPDLAGHSSSATSTP--EE-----L 642
Query: 387 KGMDK-----AQGSRPPD-QACTGDPELPERGMPAPQEAL--SPGEPL 426
+G D A S PPD + P RG PAP A +PG PL
Sbjct: 643 RGYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAPPLAFRGAPGAPL 689
Score = 59.3 bits (142), Expect = 9e-09
Identities = 80/309 (25%), Positives = 107/309 (34%), Gaps = 49/309 (15%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCP-----TSGPPAGPCP 121
PA P +P +PA P P P + +V PP P +S P A P P
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSPLATPSP 309
Query: 122 PS------PDLIYKIPRASGT--QLAAPRDALEVYDVPPTALRV----PSSGPYDCPASF 169
+ P + P +S QLA P P +L+ P++ P S
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
Query: 170 SHPLTRVA----PQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPI--YAAPSNL 223
P + P PP +P P PPA P L+ PP+ A PS
Sbjct: 370 GSPTLQATHSFLPSPPL---SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426
Query: 224 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 283
+ ++L +AP P+ P +PP+ P A+ L
Sbjct: 427 APNALAVHLLQAPFSPPPSP------------PVQAPFSPPASPPVSPSATPPSQAPPSL 474
Query: 284 LARSPP---PPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP---L 337
A PP PP P P S S P P P P A P + P P ++ P L
Sbjct: 475 AA--PPLQVPPSPPASPPM-SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531
Query: 338 PPPPPRLPG 346
P PP PG
Sbjct: 532 PSPPASFPG 540
Score = 51.6 bits (122), Expect = 2e-06
Identities = 80/290 (27%), Positives = 102/290 (35%), Gaps = 69/290 (23%)
Query: 112 TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT------------------ 153
TSGP G PSP + + RA+GT++ PR A PPT
Sbjct: 164 TSGPTPGT--PSPAMARR-SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
Query: 154 ---ALRVPSSG----------------PYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTP 194
A R PS+G P PA S P R P+ P P P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR-SGPSARGTPRAPAHPSQP-----KP 274
Query: 195 KPPAELEPDLEWEGGREPGP---PIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEG 251
K L P ++ P P+ ++P SA L P T +
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334
Query: 252 IYDVPLL--GPEAPPS----PEPPG-----ALASHDQDTLAQLLARSPPPPHRPRL---P 297
+PL P APPS P PP A S TL + P PP P P
Sbjct: 335 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394
Query: 298 SA-ESLSRRPLPALPVPEAPSP-SPVPSPAPGRKGSIQ----DRPLPPPP 341
A +L+ PL A P P A P SP+ +P+P ++ P PPP
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/292 (28%), Positives = 101/292 (34%), Gaps = 46/292 (15%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPP--------ARPC 110
P+ L A P P PASP S P P PPP A+P
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ----------APPPLAAPPLQLAKP- 515
Query: 111 PTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFS 170
P PPA PP L G +P +L P + L P P P +
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASL-----PMSPLATP---PPQAPPVLA 567
Query: 171 HPLTRVAPQPPGED--DAPYDVPLTPKPPAELE-PDLEWEGGREPGPPIYAAPSNLKRAS 227
PL +V P PP AP P TP P + P L P PP +PS+
Sbjct: 568 APLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 228 ALL----NLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 283
L + PEEL G G + G P P+A + P A + LA
Sbjct: 627 DLAGHSSSATSTPEEL--RGYDSGPEGGAAASP--PPDAELAACHPAAWSRGPAPPLAFR 682
Query: 284 LARSPPPPHRPRL--PSAESL-----SRRPLPALPVPEAPSPSPVPSPAPGR 328
A P P P SA+ L + P A P P A P P P + G+
Sbjct: 683 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGK 734
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 75.1 bits (183), Expect = 2e-13
Identities = 98/341 (28%), Positives = 125/341 (36%), Gaps = 92/341 (26%)
Query: 74 PSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRA 133
P + P P P P PAP VPPP P P PP P P P + +P A
Sbjct: 633 PRVPPLQPMGPTCPTPAP-----------VPPPEAPSPFRAPPFHPPGPMPS-VGSMPSA 680
Query: 134 SGTQLAAPRDALEVYDVPPTALRVPSSGP----------YDCPASFSHPLTRVAPQP--- 180
A P P+A VPS+ P P S P R+ P P
Sbjct: 681 GPMPSAGPM---------PSAGPVPSARPGPPTTANHLGLSVPGLVSVP-PRLLPGPENH 730
Query: 181 -PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPE-E 238
G ++ P P + PP + PD E GGR P P A + EA + E
Sbjct: 731 RAGSNEDPILAP-SGTPPPTIPPD-ETFGGRVPRP-----------AFVHYDKEEASDVE 777
Query: 239 LLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPS 298
+ + + +D+ + VP P PP P P GA +A + PP P +P+
Sbjct: 778 ISLESD---SDDSVVIVPEGLPPLPP-PPPSGATPPP--------IAPTGPPTASPPVPA 825
Query: 299 AESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRL-----PGYGGPKV- 352
E LPA P P P P P P P PG P+ PPP+L PG GGP
Sbjct: 826 KE--EPEELPAAPGP-LPPPPPPPPPVPG--------PVTLPPPQLVPEGTPGGGGPPAL 874
Query: 353 -------------EGDPEGREMEDDPAGHHNEYEGIPMAEE 380
E + E E E++ E E EE
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEE 915
Score = 48.9 bits (115), Expect = 1e-05
Identities = 73/308 (23%), Positives = 103/308 (33%), Gaps = 23/308 (7%)
Query: 57 IVPANRVKLLPAGP--APKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSG 114
IVP L P P A P ++P P P PA + E +E+ P P P P
Sbjct: 790 IVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKE---EPEELPAAPGPLPPPPPPP 846
Query: 115 PPA-GPCP-PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHP 172
PP GP P P L+ + G A D T + + SS +
Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGGGPPALEEDL--------TVININSSDEEEEEEEEEEE 898
Query: 173 LTRVAPQPPGE-DDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLN 231
+ + ++ D + E E + E E E G + L
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL- 957
Query: 232 LYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPP 291
E E+L GG +EG P L P PP PP + + L P
Sbjct: 958 --EEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTE 1015
Query: 292 HRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPP--PRLPGYGG 349
+A +L+ LP+ E SP P P + +++ P PP G
Sbjct: 1016 EERGADTAPTLAPEALPSQGEVEREGESPAAGPPP--QELVEEEPSAPPTLLEEETEDGS 1073
Query: 350 PKVEGDPE 357
KV+ PE
Sbjct: 1074 DKVQPPPE 1081
Score = 40.8 bits (94), Expect = 0.003
Identities = 91/392 (23%), Positives = 126/392 (32%), Gaps = 105/392 (26%)
Query: 68 AGPAPK----PSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCP------------ 111
AGP P PS P A+PG P A + VPP P P
Sbjct: 680 AGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPI 739
Query: 112 --TSGPPAGPCPPSPDLIYKIPR----------ASGTQLAAPRDALEVYDVPPTAL---- 155
SG P PP ++PR AS +++ D+ + + P L
Sbjct: 740 LAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLP 799
Query: 156 RVPSSGPYDCPASFSHPLTRVAPQPPGEDD-----APYDVPLTPKPPAELEPDLEWEGGR 210
P SG P + + P T P P E+ AP +P P PP + + +
Sbjct: 800 PPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQ 859
Query: 211 --EPGPPIYAAPSNLKRASALLNL----------------YEAPEELLADGEGGGTDEGI 252
G P P L+ ++N+ E EE D E DE
Sbjct: 860 LVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEE 919
Query: 253 YDVPLLGPE---APPSPEPPGALASHDQD------------------TLAQLLARSPPPP 291
Y E E G L +++ T + PPP
Sbjct: 920 YFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPP 979
Query: 292 HRPRLPSAESLSRRPLPALPVPEA-PSPSPVPSPAPG------RKGSIQDRPLPP----P 340
P LP PALP PE+ P P P P PG G+ ++R
Sbjct: 980 --PTLP----------PALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA 1027
Query: 341 PPRLPGYGGPKVEGD------PEGREMEDDPA 366
P LP G + EG+ P +E++P+
Sbjct: 1028 PEALPSQGEVEREGESPAAGPPPQELVEEEPS 1059
Score = 31.2 bits (69), Expect = 2.6
Identities = 36/116 (31%), Positives = 47/116 (40%), Gaps = 18/116 (15%)
Query: 105 PPARPCPTSGPPAGPCP-PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 163
PPA P P S P P P P P L+ ++ GT+ R A + P AL PS G
Sbjct: 983 PPALPPPESPPKVQPEPEPEPGLLLEV-EEPGTE--EERGADTAPTLAPEAL--PSQGEV 1037
Query: 164 ----DCPASFSHPLTRVAPQPPG--------EDDAPYDVPLTPKPPAELEPDLEWE 207
+ PA+ P V +P +D V P+ PAE E + E E
Sbjct: 1038 EREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETE 1093
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 75.1 bits (183), Expect = 2e-13
Identities = 102/389 (26%), Positives = 132/389 (33%), Gaps = 87/389 (22%)
Query: 56 GIVPANRVKLLPAGPAPK---PSLS----PASPAQPGSPYPAPDHSNEDQEVYVVPPPAR 108
G+ PA V LP+ P P+ P L+ PA+ P P H+ P
Sbjct: 850 GVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHT---------APRPN 900
Query: 109 PCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPAS 168
P P PP P PP L +G + P +P P GP P
Sbjct: 901 PTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIP-AGFPAPRIGPQPQPHP 959
Query: 169 FSHPLTRVAPQPPGEDDAPYDVP--LTPKPPAELEPDLEWEGGREPG------PPIYAAP 220
HP PQPP + P P P+ P L P + +PG PP++
Sbjct: 960 QPHPSQAFGPQPP-QQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHT-- 1016
Query: 221 SNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTL 280
LY P + G +P P P P PP
Sbjct: 1017 ----------QLYPGPAQDPLPAHSGA-------LPFPSPGPPQPPHPP----------- 1048
Query: 281 AQLLARSPPPPHRPRLPSAESLSRR---------PLPALPVPEAPSPSPVPSPAPGRKGS 331
LA P P RP P A L+ R P P L VP +P+PSP P P P R +
Sbjct: 1049 ---LAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHL-VP-SPAPSPGPGPVPPRPPA 1103
Query: 332 IQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK 391
+ PPP R + PE + G + G P+ + +D
Sbjct: 1104 AE----PPPCLRRGAAAADLLSSSPESQH-----GGTQSPGGGQPLLQP------TKVDA 1148
Query: 392 AQGSRPPD-QACTGDP-ELPERGMPAPQE 418
A+G RP + DP E PER QE
Sbjct: 1149 AEGRRPQALRLIERDPYEHPERLRQLQQE 1177
Score = 60.5 bits (145), Expect = 4e-09
Identities = 76/309 (24%), Positives = 105/309 (33%), Gaps = 40/309 (12%)
Query: 70 PAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTS-GPPAGPCPPSPDLIY 128
P+P PS + P P P +S Q + P P + GP P P +
Sbjct: 773 PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELG 832
Query: 129 KIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP--YDCP--ASFSHPLTRV-----APQ 179
+PR+S + V PP A +PS+ P + P A P T AP
Sbjct: 833 LVPRSSPQHGVVSSPYVGVGPAPPVA-GLPSAPPPQFSGPELAMAVRPATTTVDSIQAPI 891
Query: 180 PPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEEL 239
P P P P P + P +P P Y P+ K+ + + +
Sbjct: 892 PSHTAPRPNPTPAPPPPCFPVPPP-------QPLPTPYTYPAGAKQPIPAQHHFSS---- 940
Query: 240 LADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSP---PPPHRPRL 296
G G + P +GP+ P P+P + A Q L + P PP L
Sbjct: 941 -------GIPAG-FPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLL 992
Query: 297 PSAESLSRRPLPAL------PVPEAPSPSPVPSPAPGRKGSIQ-DRPLPPPPPRLPGYGG 349
P P P + P+ P P P P G++ P PP PP P G
Sbjct: 993 PPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYG 1052
Query: 350 PKVEGDPEG 358
P P G
Sbjct: 1053 PAPSTRPMG 1061
Score = 48.1 bits (113), Expect = 2e-05
Identities = 94/377 (24%), Positives = 136/377 (36%), Gaps = 73/377 (19%)
Query: 76 LSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPP---AGPCPPSPDLIYKIPR 132
L P +P +P P E + V PP S PP AGP P L
Sbjct: 712 LKKKPPPRPTAPKPLLPRREESEAVEAGDPPEEL--RSLPPDMVAGPRLPDTFL------ 763
Query: 133 ASGTQLAAPRDALEVYDVP-PTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVP 191
S T L P P P L SGP P ++S P + P+ PG P+ +P
Sbjct: 764 GSATPLHFPPSPFPSSTGPGPHYL----SGPLP-PGTYSGPTQLIQPRAPG----PHAMP 814
Query: 192 LTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEG 251
+ P P P E G P ++P + +S + + AP
Sbjct: 815 VAPGPALYPAPAYTPELGLVPR----SSPQHGVVSSPYVGVGPAP--------------- 855
Query: 252 IYDVPLLGPEAPPSPE---PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLP 308
P+ G + P P+ P A+A T + ++P P H P+ P P
Sbjct: 856 ----PVAGLPSAPPPQFSGPELAMAVRPATTTVDSI-QAPIPSHTAPRPN-------PTP 903
Query: 309 ALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP---PPRLP-GYGGPKVEGDPEGREMEDD 364
A P P P P P P P P + +P+P +P G+ P++ G + +
Sbjct: 904 APPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRI-----GPQPQPH 958
Query: 365 PAGHHNEYEGIPMAEE---YDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAP--QEA 419
P H ++ G ++ + HL +A G PP P+ G P P
Sbjct: 959 PQPHPSQAFGPQPPQQPLPLQHPHL-FPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQ 1017
Query: 420 LSPG---EPLVVSTGDL 433
L PG +PL +G L
Sbjct: 1018 LYPGPAQDPLPAHSGAL 1034
Score = 35.4 bits (80), Expect = 0.14
Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 27/103 (26%)
Query: 254 DVPLLGPEAPP---SPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 310
DVP+ +A S PPG L S +A P P P LP A P+P+
Sbjct: 1492 DVPISSIQATIAKLSIRPPGGLESP--------VASLPGPAEPPGLPPASLPESTPIPS- 1542
Query: 311 PVPEAPSPSPVPSPAPGRKGSIQDRPLP---PPPPRLPGYGGP 350
SP P+ SP P + P P PP P P G P
Sbjct: 1543 -----SSPPPLSSPLP-------EAPQPKEEPPVPEAPSSGPP 1573
Score = 35.0 bits (79), Expect = 0.18
Identities = 29/78 (37%), Positives = 35/78 (44%), Gaps = 13/78 (16%)
Query: 246 GGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRR 305
GG + + +P GP PP P AS + T + + SPPP P LP A
Sbjct: 1511 GGLESPVASLP--GPAEPPGLPP----ASLPEST--PIPSSSPPPLSSP-LPEAPQPKEE 1561
Query: 306 PLPALPVPEAPSPSPVPS 323
P PVPEAPS P S
Sbjct: 1562 P----PVPEAPSSGPPSS 1575
Score = 30.0 bits (66), Expect = 5.9
Identities = 20/60 (33%), Positives = 23/60 (38%), Gaps = 18/60 (30%)
Query: 69 GPAPKPSLSPAS-----------PAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPA 117
GPA P L PAS P SP P E+ PP P+SGPP+
Sbjct: 1522 GPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEE-------PPVPEAPSSGPPS 1574
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 74.3 bits (181), Expect = 3e-13
Identities = 95/381 (24%), Positives = 129/381 (33%), Gaps = 69/381 (18%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVP-PPARPCPTSG-PPAGPCPPSP 124
P GP P+ P P PG P P ++ + P P P P G P GP PP P
Sbjct: 78 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-PPPP 136
Query: 125 DLIYKIPRASGTQLAAPRDALEVYDVPP------TALRVPSSGPYDCPASFSHPLTRVAP 178
P G + P + PP + R P P P + + P
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ-PQGPP 195
Query: 179 QPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEE 238
PPG+ P P P +P +G PG P P ++ + + P+
Sbjct: 196 PPPGK-------PQGPPPQGGNKP----QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQG 244
Query: 239 LLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLP- 297
+GG +G P P P P P G + PPPP +P+ P
Sbjct: 245 --PPPQGGNQPQG----PPPPPGKPQGPPPQGGNK-----------PQGPPPPGKPQGPP 287
Query: 298 ---SAESLSRRPLPALP---------VPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLP 345
++S S R P P P+ P P P P +G ++P PPPP P
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKP 345
Query: 346 GYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGD 405
GP +G + R P + +G P E + QG PP
Sbjct: 346 --QGPPPQGGSKSRSARSPP----GKPQGPPQQEG---------NNPQGPPPPAGGNPQQ 390
Query: 406 PELPERGMP-APQEALSPGEP 425
P+ P G P P G P
Sbjct: 391 PQAPPAGQPQGPPRPPQGGRP 411
Score = 67.0 bits (162), Expect = 4e-11
Identities = 98/379 (25%), Positives = 133/379 (35%), Gaps = 89/379 (23%)
Query: 67 PAGPAPKPSLSPASP-AQPGSPY-PAPDHSNEDQEVYVVPPPARP--CPTSG--PPAGPC 120
P G P+ P P + PG P P P N+ Q PPP +P P G P GP
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPP 93
Query: 121 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP 180
PP + P G + +PR PP GP P P
Sbjct: 94 PPGKP---QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP---------------PPP 135
Query: 181 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL 240
PG+ P P P +P +G PG P P ++ + + P+
Sbjct: 136 PGK-------PQGPPPQGGNKP----QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG-- 182
Query: 241 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE 300
+GG +G P P P P P G + PPPP +P+ P +
Sbjct: 183 PPPQGGNQPQG----PPPPPGKPQGPPPQGGNK-----------PQGPPPPGKPQGPPPQ 227
Query: 301 ----SLSRRPLPALP---------VPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGY 347
S S R P P P+ P P P P +G ++P PPPP P
Sbjct: 228 GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKP-- 283
Query: 348 GGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPE 407
GP +G + R P + +G P +G ++ QG PP G P+
Sbjct: 284 QGPPPQGGSKSRSSRSPP----GKPQGPPP---------QGGNQPQGPPPP----PGKPQ 326
Query: 408 -LPERGMPAPQEALSPGEP 425
P +G PQ PG+P
Sbjct: 327 GPPPQGGNKPQGPPPPGKP 345
Score = 56.2 bits (134), Expect = 8e-08
Identities = 74/290 (25%), Positives = 90/290 (31%), Gaps = 29/290 (10%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPP--PARPCPTSG-PPAGPCPPS 123
P GP P+ P P PG P P + PP P P P G P GP PP
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP-PPP 197
Query: 124 PDLIYKIPRASGTQLAAPRDALEVYDVPPT------ALRVPSSGPYDCPASFSHPLTRVA 177
P P G + P + PP + R P P P + +
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ-PQGP 256
Query: 178 PQPPGEDDAPY----DVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLY 233
P PPG+ P + P P PP G+ GPP + S
Sbjct: 257 PPPPGKPQGPPPQGGNKPQGPPPP-----------GKPQGPPPQGGSKSRSSRSPPGKPQ 305
Query: 234 EAPEELLADGEGGGTDEGI-YDVPLLGPEAPPSPEPPGA-LASHDQDTLAQLLARSPP-P 290
P + +G G P G P P PPG Q ARSPP
Sbjct: 306 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK 365
Query: 291 PHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP 340
P P + P PA P+ P P P + RP PP
Sbjct: 366 PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 73.2 bits (178), Expect = 6e-13
Identities = 112/401 (27%), Positives = 140/401 (34%), Gaps = 94/401 (23%)
Query: 67 PAGPAPKPSLS--PASPAQP--------GSPYPAPDHSNEDQEVYVVPPPARPCPTSGPP 116
P P+ PSL P+ PA P GSP HS ++ PP P T P
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS------FLPSPPLSPLATPPPQ 356
Query: 117 AGPC--------PPSPDLIYKIPRASGTQLAAPRDALEV------YDVPPTALRVPSSGP 162
A P PPSP + + AP +AL V + PP+ P P
Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAP-NALAVHLLQAPFSPPPSP---PVQAP 412
Query: 163 YDCPAS--FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAP 220
+ PAS S T + PP P VP P PPA + PP+ A P
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATPPPQAPPPLAAPP 470
Query: 221 SNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTL 280
L + +AP L P P PP + +
Sbjct: 471 LQLAKPPP-----QAPPALAT------------------PPLQALPSPPASFPGQAPFSP 507
Query: 281 AQLLARSP---PPPHRPRLPSAESLSRRPLP-ALPVPEAPSPSPVPSP---APGRKGSIQ 333
+ L SP PPP P + +A L P P A P +AP P P P G + ++
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567
Query: 334 DRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK-- 391
P PPPPP P D AGH + P EE L+G D
Sbjct: 568 LAPGPPPPP----------SRSPSSTLSGPDLAGHSSSATSTP--EE-----LRGYDSGP 610
Query: 392 ---AQGSRPPD-QACTGDPELPERGMPAPQEAL--SPGEPL 426
A S PPD + P RG PAP A +PG PL
Sbjct: 611 EGGAAASPPPDAELAACHPAAWSRG-PAPPLAFRGAPGAPL 650
Score = 58.5 bits (140), Expect = 2e-08
Identities = 76/292 (26%), Positives = 101/292 (34%), Gaps = 45/292 (15%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDL 126
PA P +P +PA P P P + + P P + P GP SP L
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKP------KGLQALRPPQVTPPRKDAAPALGPLSSSP-L 295
Query: 127 IYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVA----PQPPG 182
P A + A P +L+ PP ++ P S P + P PP
Sbjct: 296 ATPSPSAPPSPSAPP--SLQTLPSPP------ATPPSQATTSLGSPTLQATHSFLPSPPL 347
Query: 183 EDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPI--YAAPSNLKRASALLNLYEAPEELL 240
+P P PPA P L+ PP+ A PS + ++L +AP
Sbjct: 348 ---SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 241 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPP---PPHRPRLP 297
P+ P +PP+ P A+ L A PP PP P P
Sbjct: 405 PSP------------PVQAPFSPPASPPVSPSATPPSQAPPSLAA--PPLQVPPSPPASP 450
Query: 298 SAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP---LPPPPPRLPG 346
S S P P P P A P + P P ++ P LP PP PG
Sbjct: 451 PM-SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/292 (28%), Positives = 101/292 (34%), Gaps = 46/292 (15%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPP--------ARPC 110
P+ L A P P PASP S P P PPP A+P
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ----------APPPLAAPPLQLAKP- 476
Query: 111 PTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFS 170
P PPA PP L G +P +L P + L P P P +
Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASL-----PMSPLATP---PPQAPPVLA 528
Query: 171 HPLTRVAPQPPGED--DAPYDVPLTPKPPAELE-PDLEWEGGREPGPPIYAAPSNLKRAS 227
PL +V P PP AP P TP P + P L P PP +PS+
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587
Query: 228 ALL----NLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 283
L + PEEL G G + G P P+A + P A + LA
Sbjct: 588 DLAGHSSSATSTPEEL--RGYDSGPEGGAAASP--PPDAELAACHPAAWSRGPAPPLAFR 643
Query: 284 LARSPPPPHRPRL--PSAESL-----SRRPLPALPVPEAPSPSPVPSPAPGR 328
A P P P SA+ L + P A P P A P P P + G+
Sbjct: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGK 695
Score = 50.1 bits (118), Expect = 5e-06
Identities = 69/248 (27%), Positives = 87/248 (35%), Gaps = 40/248 (16%)
Query: 112 TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSH 171
TSGP G PSP + + RA+GT++ PR A P R P+ GP +S S
Sbjct: 155 TSGPTPGT--PSPAMARR-SRAAGTEVGLPRPA------PSARPRPPTEGPRKSVSSASE 205
Query: 172 -------PLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGR-EPGPPIYAAPSNL 223
P R P G P L+ P R P P + +
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 265
Query: 224 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 283
K AL P A G P P APPSP P +L +
Sbjct: 266 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATP--SPSAPPSPSAPPSLQT--------- 314
Query: 284 LARSPPPPHRPRLPSAESLSRRPLPA----LPVPEAPSPSPVPSPAPGRKGSIQDRPL-- 337
P PP P + SL L A LP +P SP+ +P P ++ PL
Sbjct: 315 ---LPSPPATPPSQATTSLGSPTLQATHSFLP---SPPLSPLATPPPQAPPALALPPLQA 368
Query: 338 PPPPPRLP 345
PP PP P
Sbjct: 369 PPSPPASP 376
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 72.4 bits (176), Expect = 1e-12
Identities = 86/315 (27%), Positives = 112/315 (35%), Gaps = 66/315 (20%)
Query: 65 LLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPA-RPCPTSGPPAGPCPPS 123
++ PA PA+PA+ G+P AP+ PPPA R P G P P PPS
Sbjct: 62 VVSGSPAGAAGAGPAAPAE-GAPGAAPE-----------PPPAGRARPGGGGPQRPGPPS 109
Query: 124 P--DLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPL------TR 175
P L+ P +L P + P A ++GP PA + P R
Sbjct: 110 PRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAAR 169
Query: 176 VAPQP-PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYE 234
P P PG P P G+ GP A L ++ALLN +
Sbjct: 170 AGPGPGPGPGPGPGPGP-----------------GKPAGP---GAAQTLNGSAALLNSHH 209
Query: 235 A-----------PEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 283
A P LL + I P +G APP+P P A+ A
Sbjct: 210 AAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAA---PAPAAP 266
Query: 284 LARSPPPPHRP----RLPSAESLSRRPLPALPVPEAPS------PSPVPSPAPGRKGSIQ 333
A PPPP P R P + PA+P P A +P P+PA G +
Sbjct: 267 AAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326
Query: 334 DRPLPPPPPRLPGYG 348
+P P P G
Sbjct: 327 GQPGPGAAAAAPAPG 341
Score = 52.0 bits (123), Expect = 1e-06
Identities = 81/303 (26%), Positives = 108/303 (35%), Gaps = 49/303 (16%)
Query: 59 PANRVKLLPAGPAPKPSLS--------------PASPAQPGSPYPAPDHSNEDQEVYVVP 104
P+ R L+PAGPAP + PA+ A P PAP + +
Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALA 167
Query: 105 PPARPCPTSGPPAGPCP----PSPDLIYKIPRASGTQL-----AAPRDALEVYDVPPTAL 155
A P P GP GP P P+ + S L AAP +L V + P L
Sbjct: 168 ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL-VNNGPAALL 226
Query: 156 RVPSSG---------PYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEW 206
+P P+ A+ P AP PP AP P PP L
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAA---PPAPAAPSPPAAP-APAAPAAAPPPPPPAPATLAR 282
Query: 207 EGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSP 266
G GPP AAP+ A+A A GG G+ P GP A +
Sbjct: 283 PPGHPAGPPT-AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA--GVSGQP--GPGAAAAA 337
Query: 267 EPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEA--PSPSPVPSP 324
PG A + + ++ PP + S + + + P + PSP+ VP P
Sbjct: 338 PAPGVKAESPKRVV-----QAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392
Query: 325 APG 327
APG
Sbjct: 393 APG 395
Score = 49.7 bits (117), Expect = 7e-06
Identities = 74/293 (25%), Positives = 97/293 (33%), Gaps = 48/293 (16%)
Query: 51 LHGQQGIVPANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPC 110
L+ PA V L+ GPA L PA PG+ P P PA P
Sbjct: 205 LNSHHAAAPA--VSLVNNGPAALLPLP--KPAAPGTVIQTPPFVG----AAAPPAPAAPS 256
Query: 111 PTSGP----PAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCP 166
P + P PA PP P + R G A P A P A S+G P
Sbjct: 257 PPAAPAPAAPAAAPPPPPPAPATLARPPGHP-AGPPTAAPAVPPPAAAQNGGSAGAAPAP 315
Query: 167 ASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRA 226
A + V+ QP P P P + E P + AAP +
Sbjct: 316 APAAGGPAGVSGQP-----GPGAAAAAPAPGVKAE---------SPKRVVQAAPPAAQTL 361
Query: 227 SALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLAR 286
+A P A G T +G P P PP+P P L + Q L+R
Sbjct: 362 AA-----SGPASTAASMVIGPTMQGALPSPAAVP--PPAPGTPTGLPKGAAGAVTQSLSR 414
Query: 287 SPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 339
+P + + P + P P P P+ +IQ+ LPP
Sbjct: 415 TP-------TATTSGIRATLTPTVLAPRLPQPPQNPT-------NIQNFQLPP 453
Score = 37.0 bits (84), Expect = 0.048
Identities = 49/192 (25%), Positives = 66/192 (34%), Gaps = 23/192 (11%)
Query: 279 TLAQLLARSPPPPHR--PRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP 336
+L LA S H PR P + + L V +P+ + PA +G+ P
Sbjct: 28 SLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP 87
Query: 337 LPPPPPRL-PGYGGPKVEGDPEGR-------------EMEDDPAGHHNEYEGIPMAEEYD 382
PPP R PG GGP+ G P R ++ P G +P A
Sbjct: 88 EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV- 146
Query: 383 YVHLKGMDKAQG--SRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYA 440
G + A ++P A P G P P PG G Q L A
Sbjct: 147 ---AAGPEPAPAGPAKPAGPAALAARAGPGPG-PGPGPGPGPGPGKPAGPGAAQTLNGSA 202
Query: 441 GQCQSHYSALQA 452
SH++A A
Sbjct: 203 ALLNSHHAAAPA 214
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 72.0 bits (175), Expect = 1e-12
Identities = 105/372 (28%), Positives = 125/372 (33%), Gaps = 81/372 (21%)
Query: 61 NRVKLLPAGPAPKPSLSPASPAQPGS-PYPAPDHSNEDQEVYV--VPPPARPC----PTS 113
+R LLP G + + P+ PG P P+P H + E +PPP RP P S
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPP-RPDVGSKPDS 182
Query: 114 GPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP------TALRVPSSGPYDCPA 167
PP P P P R S PR PP TAL S P
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIR--QSPL 240
Query: 168 SFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS 227
S S P + P PP A D P P PP P + E P PP P N K
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA--VPPPP----PQNNKPP- 293
Query: 228 ALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARS 287
+ P P +APP P PP +R
Sbjct: 294 ----VPSTPR------------------PSASSQAPPPPPPP---------------SRP 316
Query: 288 PPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGY 347
PPP P + R P L + S S P P+PGR G PLPPPP P
Sbjct: 317 GPPPLPPSSSGNDETPRLPQRNLSL----SSSTPPLPSPGRSG-----PLPPPPSERP-- 365
Query: 348 GGPKVEGDPEGRE--MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQ-GSRPPDQACTG 404
P DP GR + P N + G+D + G RPP
Sbjct: 366 --PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP-----L 418
Query: 405 DPELPERGMPAP 416
P+ P G P P
Sbjct: 419 PPDRPSAGAPPP 430
Score = 49.7 bits (117), Expect = 7e-06
Identities = 79/295 (26%), Positives = 96/295 (32%), Gaps = 92/295 (31%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG 118
P NR L G + LS +SP P P P P+R PP
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLP--------------PTPSRALDDKPPP-- 266
Query: 119 PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAP 178
PP P G + + R+A VPP P + P P
Sbjct: 267 --PPPP---------VGNRPSIHREA-----VPPP------------PPQNNKPPVPSTP 298
Query: 179 QPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKR-ASALLNLYEAPE 237
+P AP P PP P G P PP + R L+L +
Sbjct: 299 RPSASSQAP------PPPPPPSRP------GPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 238 ELLADGEGGGTDEGIYDVPLLGPEAPPSP--EPPGALASHDQDTLAQLLARSPPPPHRPR 295
L + G G +P E PP P +PPG RS P P P
Sbjct: 347 PLPSPGRSG-------PLPPPPSERPPPPVRDPPG---------------RSGPLPPPPP 384
Query: 296 LPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGP 350
+ S + R LPA P+ PS S V SP G P PP PP P G P
Sbjct: 385 V-SRNGSTSRALPA--TPQLPSRSGVDSPRSG--------PRPPLPPDRPSAGAP 428
Score = 42.7 bits (99), Expect = 9e-04
Identities = 52/190 (27%), Positives = 70/190 (36%), Gaps = 33/190 (17%)
Query: 251 GIYDVPLLGPEA-PPSPE-----PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSR 304
G + VP G + PP P+ PP D++ PP P PR P S
Sbjct: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP------PPVPSTPR-PIQSSPHN 200
Query: 305 RPLPALPV-PEAPSPSPVPSPAPGRK------GSIQDRPLPPPPPRLPGYGGPKVEGDPE 357
R P +P P PSP P P P PG + GSI+ PL P P + P
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSS---PFSNRPPLPPTP- 256
Query: 358 GREMEDDPAGHHNEYEGIPMAEEYDYVHLKGM--DKAQGSRPPDQACTGDPELPERGMPA 415
R ++D P P +H + + Q ++PP + T P + P
Sbjct: 257 SRALDDKPP------PPPPPVGNRPSIHREAVPPPPPQNNKPPVPS-TPRPSASSQAPPP 309
Query: 416 PQEALSPGEP 425
P PG P
Sbjct: 310 PPPPSRPGPP 319
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 34/179 (18%)
Query: 50 SLHGQQGIVPANRVKLLPAGPAPKPSLS------PASPAQPGSPYPAPDHSNEDQEVYVV 103
S+H + P + P P+PS S P P++PG P P P S+ + E +
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRL 334
Query: 104 PPPARPCPTSGPP------AGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRV 157
P +S PP +GP PP P + R V D P + +
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPP---------------SERPPPPVRDPPGRSGPL 379
Query: 158 PSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLT-PKPPAELEPDLEWEGGREPGPP 215
P P S S L PQ P D P + P+PP L PD G P PP
Sbjct: 380 PPPPPVSRNGSTSRALP-ATPQLPSRSGV--DSPRSGPRPP--LPPDRPSAGAPPPPPP 433
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 72.0 bits (175), Expect = 1e-12
Identities = 105/372 (28%), Positives = 125/372 (33%), Gaps = 81/372 (21%)
Query: 61 NRVKLLPAGPAPKPSLSPASPAQPGS-PYPAPDHSNEDQEVYV--VPPPARPC----PTS 113
+R LLP G + + P+ PG P P+P H + E +PPP RP P S
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPP-RPDVGSKPDS 182
Query: 114 GPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP------TALRVPSSGPYDCPA 167
PP P P P R S PR PP TAL S P
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIR--QSPL 240
Query: 168 SFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS 227
S S P + P PP A D P P PP P + E P PP P N K
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA--VPPPP----PQNNKPP- 293
Query: 228 ALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARS 287
+ P P +APP P PP +R
Sbjct: 294 ----VPSTPR------------------PSASSQAPPPPPPP---------------SRP 316
Query: 288 PPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGY 347
PPP P + R P L + S S P P+PGR G PLPPPP P
Sbjct: 317 GPPPLPPSSSGNDETPRLPQRNLSL----SSSTPPLPSPGRSG-----PLPPPPSERP-- 365
Query: 348 GGPKVEGDPEGRE--MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQ-GSRPPDQACTG 404
P DP GR + P N + G+D + G RPP
Sbjct: 366 --PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP-----L 418
Query: 405 DPELPERGMPAP 416
P+ P G P P
Sbjct: 419 PPDRPSAGAPPP 430
Score = 49.7 bits (117), Expect = 7e-06
Identities = 79/295 (26%), Positives = 96/295 (32%), Gaps = 92/295 (31%)
Query: 59 PANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG 118
P NR L G + LS +SP P P P P+R PP
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLP--------------PTPSRALDDKPPP-- 266
Query: 119 PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAP 178
PP P G + + R+A VPP P + P P
Sbjct: 267 --PPPP---------VGNRPSIHREA-----VPPP------------PPQNNKPPVPSTP 298
Query: 179 QPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKR-ASALLNLYEAPE 237
+P AP P PP P G P PP + R L+L +
Sbjct: 299 RPSASSQAP------PPPPPPSRP------GPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 238 ELLADGEGGGTDEGIYDVPLLGPEAPPSP--EPPGALASHDQDTLAQLLARSPPPPHRPR 295
L + G G +P E PP P +PPG RS P P P
Sbjct: 347 PLPSPGRSG-------PLPPPPSERPPPPVRDPPG---------------RSGPLPPPPP 384
Query: 296 LPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGP 350
+ S + R LPA P+ PS S V SP G P PP PP P G P
Sbjct: 385 V-SRNGSTSRALPA--TPQLPSRSGVDSPRSG--------PRPPLPPDRPSAGAP 428
Score = 42.7 bits (99), Expect = 9e-04
Identities = 52/190 (27%), Positives = 70/190 (36%), Gaps = 33/190 (17%)
Query: 251 GIYDVPLLGPEA-PPSPE-----PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSR 304
G + VP G + PP P+ PP D++ PP P PR P S
Sbjct: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP------PPVPSTPR-PIQSSPHN 200
Query: 305 RPLPALPV-PEAPSPSPVPSPAPGRK------GSIQDRPLPPPPPRLPGYGGPKVEGDPE 357
R P +P P PSP P P P PG + GSI+ PL P P + P
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSS---PFSNRPPLPPTP- 256
Query: 358 GREMEDDPAGHHNEYEGIPMAEEYDYVHLKGM--DKAQGSRPPDQACTGDPELPERGMPA 415
R ++D P P +H + + Q ++PP + T P + P
Sbjct: 257 SRALDDKPP------PPPPPVGNRPSIHREAVPPPPPQNNKPPVPS-TPRPSASSQAPPP 309
Query: 416 PQEALSPGEP 425
P PG P
Sbjct: 310 PPPPSRPGPP 319
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 34/179 (18%)
Query: 50 SLHGQQGIVPANRVKLLPAGPAPKPSLS------PASPAQPGSPYPAPDHSNEDQEVYVV 103
S+H + P + P P+PS S P P++PG P P P S+ + E +
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRL 334
Query: 104 PPPARPCPTSGPP------AGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRV 157
P +S PP +GP PP P + R V D P + +
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPP---------------SERPPPPVRDPPGRSGPL 379
Query: 158 PSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLT-PKPPAELEPDLEWEGGREPGPP 215
P P S S L PQ P D P + P+PP L PD G P PP
Sbjct: 380 PPPPPVSRNGSTSRALP-ATPQLPSRSGV--DSPRSGPRPP--LPPDRPSAGAPPPPPP 433
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 71.6 bits (174), Expect = 2e-12
Identities = 85/330 (25%), Positives = 124/330 (37%), Gaps = 73/330 (22%)
Query: 54 QQGIVPANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTS 113
Q + P + ++PAGP P P S A + G P+ E P P
Sbjct: 524 QPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQG----------PSPGD 573
Query: 114 GPPAGPCPPSPDLIYKIPRASGTQLAA----PRDALEVYDVPPTALRVPSSGPYDCPASF 169
G P P P + P + +Q+A+ P+ A + + ++ P + P +
Sbjct: 574 GSPPKPKDPVSAAV-PAPGRNNSQIASGQNQPQAAAGSHQL---SMGQPHNAAGPSPHTL 629
Query: 170 SHPLTRVAPQPPGEDDAPYDVP--------------LTPKPPAELEPDLEWEGGREPGPP 215
+ + AP PP + P P L+PKPP G+ PG P
Sbjct: 630 RRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQP 689
Query: 216 IYAAPSNL---KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGAL 272
+APS L +R S+ L+ +AP T PL+ + P S PP +
Sbjct: 690 --SAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQAT-------PLMHTK-PNSQGPPNPM 739
Query: 273 ASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEA----------------P 316
A + L Q S PP P PS L ++ P+LP P+ P
Sbjct: 740 ALPSEHGLEQ---PSHTPPQTPTPPSTPPLGKQN-PSLPAPQTLAGGNPETAQPHAGTLP 795
Query: 317 SPSPVPSPAPGRKGSIQDRPLPPPPPRLPG 346
P PVP P ++RP PPPP+ PG
Sbjct: 796 RPRPVPKP--------RNRPSVPPPPQPPG 817
Score = 43.9 bits (102), Expect = 4e-04
Identities = 62/263 (23%), Positives = 90/263 (34%), Gaps = 56/263 (21%)
Query: 68 AGPAP--------KPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGP 119
AGP+P KP+ +P P P +P S+ + PP P P P P
Sbjct: 622 AGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQH---PPSLSPKP---PTRSP 675
Query: 120 CPPSPDLIYKIPRASG-TQLAAPRDALEVYDVPPTALRVPSSGP-----------YDCPA 167
PP+ + S +QL+APR Y + ++ P+ P + P
Sbjct: 676 SPPTQHTGQPPGQPSAPSQLSAPRR----YSSSLSPIQAPNHPPPQPPTQATPLMHTKPN 731
Query: 168 SFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS 227
S P P G + + P TP PP+ P L + P P A N + A
Sbjct: 732 SQGPPNPMALPSEHGLEQPSHTPPQTPTPPST--PPLGKQNPSLPAPQTLAG-GNPETAQ 788
Query: 228 ALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQD------TLA 281
P + P P PP P+PPG ++ D T +
Sbjct: 789 PHAGTLPRPRPV--------------PKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTAS 834
Query: 282 QLLARS---PPPPHRPRLPSAES 301
+++ S PHR P S
Sbjct: 835 KIVTDSNSRVSEPHRSIFPEMHS 857
Score = 33.9 bits (76), Expect = 0.41
Identities = 39/134 (29%), Positives = 43/134 (32%), Gaps = 21/134 (15%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAG---PCPPS 123
P P L P G P P S E PP P P S PP G P P+
Sbjct: 716 PQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPA 775
Query: 124 PDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGE 183
P + A G A P A +P P P + P PQPPG
Sbjct: 776 PQTL-----AGGNPETA----------QPHAGTLPR--PRPVPKPRNRPSVPPPPQPPGV 818
Query: 184 DDAPYDVPLTPKPP 197
A D LT P
Sbjct: 819 HSAG-DSSLTNTAP 831
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 71.2 bits (173), Expect = 2e-12
Identities = 116/385 (30%), Positives = 138/385 (35%), Gaps = 71/385 (18%)
Query: 67 PAGPAPKPS-LSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPP-AGPCPPSP 124
P P P+ S LSP P SP P H + E + PP P S PP + P P
Sbjct: 457 PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLE 516
Query: 125 DLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGED 184
+ P S P ALE PP P + P P S PL+ PP
Sbjct: 517 ESPLSPPEES-----PPSPALETPLSPP-----PEASPLSPPFEES-PLS-----PP--- 557
Query: 185 DAPYDVPLTPKPPA-ELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYE------APE 237
P ++P +P P A L P E E P PP + S AS L +E PE
Sbjct: 558 --PEELPTSPPPEASRLSPPPE-ESPMSP-PPEESPMSPPPEASRLFPPFEESPLSPPPE 613
Query: 238 E--LLADGEGGGTDEGIYDVPLLGP--EAPPSPEPPGALASHDQDTLAQLLARSPPPPHR 293
E L E D P+ P E+P SP P + S L + SPPP
Sbjct: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS----PLPVVSRLSPPPEES 669
Query: 294 PRLPSAESLSRRPLPAL----PVPE--APSPSPVPSPA-PGRKGSIQD--------RPLP 338
P P E P P P PE SP P SPA P + S+ PLP
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Query: 339 PPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPP 398
P P GP + PE + P H P AEE HL S P
Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS----PQAEE---PHL--------SPQP 774
Query: 399 DQAC-TGDPELPERGMPAPQEALSP 422
++ C PE P A LSP
Sbjct: 775 EEPCLCAVPEEPHLSPQAEGPHLSP 799
Score = 65.5 bits (158), Expect = 1e-10
Identities = 104/377 (27%), Positives = 141/377 (37%), Gaps = 67/377 (17%)
Query: 66 LPAGPAPKPSLSPASPA--QPGSPYP-APDHSNEDQEVYVVPPPARPCPTSGPP-AGPCP 121
L P P SP SPA P SP P A S +E + PPP PTS PP A
Sbjct: 515 LEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP-EELPTSPPPEASRLS 573
Query: 122 PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP 181
P P+ P + ++ P +A ++ PP S P + P S +R++P P
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLF--PPFEESPLSPPPEESPLSPPPEASRLSPPPE 631
Query: 182 GEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLA 241
D P++P P E P P + S L + L PEE
Sbjct: 632 -------DSPMSPPPE---------ESPMSPPPEV----SRLSPLPVVSRLSPPPEE--- 668
Query: 242 DGEGGGTDEGIYDVPLLGP--EAPPSPEPPGA-LASHDQDTLAQLLARSPPPPHRPRLPS 298
PL P E+P SP P + L+ +D+ SPPP P P
Sbjct: 669 -------------SPLSPPPEESPTSPPPEASRLSPPPEDS-----PTSPPPEDSPASPP 710
Query: 299 AE-SLSRRPL---PALPVPEAP-----SPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGG 349
E SL PL P LP+PE P S P SP P P P P P
Sbjct: 711 PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP---HLSPRPEEPHLSPQAEE 767
Query: 350 PKVEGDPEGREMEDDPAGHH--NEYEGIPMAEEYDYVHLKGMDKAQGSRP-PDQAC-TGD 405
P + PE + P H + EG ++ + + +HL + P P++ C +
Sbjct: 768 PHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQ 827
Query: 406 PELPERGMPAPQEALSP 422
PE + + LSP
Sbjct: 828 PEESHLSPQSEEPCLSP 844
Score = 60.1 bits (144), Expect = 5e-09
Identities = 92/358 (25%), Positives = 126/358 (35%), Gaps = 52/358 (14%)
Query: 97 DQEVYVVP--------PPARPCPTSGPP-AGPCPPSPDLIYKIPRASGTQLAAPRDALEV 147
++E+ ++P PP PTS PP A P P+ + P L+ P LE
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP---LEE 491
Query: 148 YDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAP---YDVPLTPKPPAE-LEPD 203
+ P P S P P S +P P E+ P + PL+P P A L P
Sbjct: 492 SPLSPPPEESPLSPP---PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP 548
Query: 204 LEWEGGREPGPPIYAAP----SNLKRASALLNLYEAPEE--LLADGEGGGTDEGIYDVPL 257
E P + +P S L + PEE + E + PL
Sbjct: 549 FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608
Query: 258 LGP--EAPPSPEPPGA-LASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL---- 310
P E+P SP P + L+ +D+ SPPP P P E PLP +
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDS-----PMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663
Query: 311 PVPEAPSPSPVPSPAPGRKGSIQDRPLPPP------PPRLPGYGGPKVEGDPEGREMEDD 364
P PE SP P +P R PPP PP P E +E+
Sbjct: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723
Query: 365 PAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSP 422
P +P+ EE + + RP + + PE P A + LSP
Sbjct: 724 PL--------LPLPEE-PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772
Score = 56.6 bits (135), Expect = 6e-08
Identities = 75/279 (26%), Positives = 105/279 (37%), Gaps = 53/279 (18%)
Query: 73 KPSLSPASPAQPGSPYPAPDH-SNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIP 131
+P LSP + SP P H S + +E ++ P P PC + P P + P
Sbjct: 785 EPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP 844
Query: 132 RASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVP 191
R + L+ + PP + P P+ PG+ AP ++P
Sbjct: 845 RPEESHLSPELEK------PPLS-----------------PRPEKPPEEPGQCPAPEELP 881
Query: 192 LTPKPPAE--LEPDLEWEGGREPG-PPIYAAPSNLKRASA---LLNLYEAPEELLADGEG 245
L P PP E L P L EPG PP+ P L + + L+ P + L
Sbjct: 882 LFP-PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLS 940
Query: 246 GGTDEGIYDVPLLGPEAPPSPEPPGAL-----ASHDQDTLAQLLARSPPPPHRPRLPSAE 300
P++ APP+ P G L A D D + L A P P P A
Sbjct: 941 ----------PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPP-PEAN 989
Query: 301 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 339
P+P + +P +P SPV +P I PLPP
Sbjct: 990 CTDPEPVPPMILPPSPG-SPVGPASP-----ILMEPLPP 1022
Score = 55.5 bits (132), Expect = 1e-07
Identities = 87/320 (27%), Positives = 113/320 (35%), Gaps = 51/320 (15%)
Query: 67 PAGPAPKPS-LSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGP--CPPS 123
P P P+ S +SP SP P + E + PP PTS PP PP
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693
Query: 124 PDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGE 183
D P P D+L + + L P CP S P P+ P
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS-EGPHLSPRPEEPHL 752
Query: 184 DDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPS--NLKRASALLNLYEAPEELLA 241
P + L+P+ EP L + P + A P +L + +L PEEL
Sbjct: 753 SPRPEEPHLSPQAE---EPHLS---PQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHL 806
Query: 242 DGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAES 301
+ T+E P P PE P Q + L +S P PR P
Sbjct: 807 SPQ---TEE---------PHLSPVPEEP---CLSPQPEESHLSPQSEEPCLSPR-PEESH 850
Query: 302 LS---RRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPP-----------PRLPGY 347
LS +P P P PE P P PAP ++ PL PPP P L
Sbjct: 851 LSPELEKP-PLSPRPEKPPEEPGQCPAP------EELPLFPPPGEPSLSPLLGEPALSEP 903
Query: 348 GGPKVEGDPEGREMEDDPAG 367
G P + PE E+ P+G
Sbjct: 904 GEPPLSPLPE--ELPLSPSG 921
Score = 53.5 bits (127), Expect = 5e-07
Identities = 81/315 (25%), Positives = 109/315 (34%), Gaps = 66/315 (20%)
Query: 67 PAGPAPKPS-LSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPA-GPCPPSP 124
P P P+ S L P P SP P + E + PP P S PP P P P
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
Query: 125 DLIYKIPRASGTQLAAPRDALEVY--------DVPPTALRVPSSGPYDCPASFSHPLTRV 176
++ P ++L+ P + + PP A R+ S P D P S P
Sbjct: 649 EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL-SPPPEDSPTS---PPPED 704
Query: 177 APQPPGEDDAPYDVPLTPKP--PAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYE 234
+P P +D+ +PL P P EP L R GP + P +L
Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQL---CPRSEGPHLSPRPEEP-------HLSP 754
Query: 235 APEELLADGEGGGTDEGIYDVPLLGPEAP-----PSPEPPGALASHDQDTL---AQLLAR 286
PEE P L P+A P PE P A ++ L A+
Sbjct: 755 RPEE-----------------PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
Query: 287 SPPP-----------PHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDR 335
SP P PH +P LS +P + P++ P P P ++
Sbjct: 798 SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857
Query: 336 ----PLPPPPPRLPG 346
P P PP PG
Sbjct: 858 PPLSPRPEKPPEEPG 872
Score = 52.8 bits (125), Expect = 8e-07
Identities = 69/277 (24%), Positives = 104/277 (37%), Gaps = 48/277 (17%)
Query: 153 TALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREP 212
T+++ GP C A PL + Q + +AP + + PP E P
Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESP---------L 449
Query: 213 GPPIYAAPSNLKRASALLNLYEAPEELLADG--EGGGTDEGIYDVPLLGPEAPPSPEPPG 270
PP +P++ ++ L+ PEEL A E + + PL +PP E P
Sbjct: 450 SPPPEESPTSPPPEASRLS--PPPEELPASPLPEALHLSRPLEESPL----SPPPEESP- 502
Query: 271 ALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKG 330
SPPP P P ES P + P P +P P A
Sbjct: 503 ---------------LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547
Query: 331 SIQDRPLPPPPPRLPGYGGP---KVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHL- 386
++ PL PPP LP P ++ PE M P E PM+ + L
Sbjct: 548 PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP-------EESPMSPPPEASRLF 600
Query: 387 KGMDKAQGSRPPDQACTGDPELPERGMPAPQEA-LSP 422
+++ S PP+++ P R P P+++ +SP
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Score = 51.2 bits (121), Expect = 2e-06
Identities = 105/403 (26%), Positives = 141/403 (34%), Gaps = 86/403 (21%)
Query: 73 KPSLSPASPAQPG---SPYPAPDHSNEDQEVYVVPPPARPCPTSG-------PPAG--PC 120
+P+L P QPG SP PA + P P S PPAG P
Sbjct: 2099 RPALHLRIPPQPGALGSPPPAA------APTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152
Query: 121 PPSP-DLIYKIPRASGTQLAA--PRDALEVYDVPPTALRVPSS-GPYDCP--ASFSHPLT 174
P SP +L K+P Q+ + P Y + P P + PY P A P+
Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPML 2212
Query: 175 RVAPQP----PGE-----DDAPYDVPLTPKPPAELE---------PDLEWEGGREPGPPI 216
+ +P PGE P P TP P + P+ GG + P+
Sbjct: 2213 GASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL 2272
Query: 217 YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLG-PEAPPSPEPPGALASH 275
+ P + AL E +E L G Y P LG ++P S G L
Sbjct: 2273 LSPPPFGESRKAL----EVKKEEL------GASSPSYGPPNLGFVDSPSSGTHLGGLELK 2322
Query: 276 DQDTLAQLLARSPPPPHRPRL-PSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQD 334
D ++P P ++ P + L RP P +A +PSP P R GS D
Sbjct: 2323 TPDVF-----KAPLTPRASQVEPQSPGLGLRPQEPPPA-QALAPSPPSHPDIFRPGSYTD 2376
Query: 335 ---------RPLPPPP-------PR-LPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPM 377
RP PPPP PR LP +V P+ + P P+
Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR------PL 2430
Query: 378 AEEY---DYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQ 417
+ E V + SRPP + + DP P P PQ
Sbjct: 2431 SAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQ 2473
Score = 51.2 bits (121), Expect = 2e-06
Identities = 107/425 (25%), Positives = 149/425 (35%), Gaps = 98/425 (23%)
Query: 58 VPANRVKLLPAGPAPKPSLSPASPAQPGS--PYPAP---------------DHSNEDQEV 100
VPA P G AP L P P P + PYP+P + + E
Sbjct: 2167 VPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEF 2226
Query: 101 YVVPP--PARPCPTSGPPAGPCPPSPD--LIYKIPRASGTQLAAP----------RDALE 146
+ PP P T P P PS D + + P G + + P R ALE
Sbjct: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286
Query: 147 V----YDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEP 202
V + P+ G D P+S +H L + + P + PLTP+ +++EP
Sbjct: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTH-LGGLELKTPD----VFKAPLTPR-ASQVEP 2340
Query: 203 DLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTD---EGIYDVPLLG 259
G R PP P + LA D G Y P
Sbjct: 2341 QSPGLGLRPQEPP--------------------PAQALAPSPPSHPDIFRPGSYTDPYAQ 2380
Query: 260 PEAPPSPEPPGALASHDQDTLAQLLARSPP--PPHR-PRLPSAESLSRRPLPALPV-PEA 315
P P P+PP ++ L RS P P R P P ++S S+ PL P+ EA
Sbjct: 2381 PPLTPRPQPP------PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434
Query: 316 PSPSPV--------PSPAPGRKGSIQD------RPLPPPPPRLPGYGGPKVEGD-PEGRE 360
PSPV P P + +D +P P PP + G G
Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGF 2494
Query: 361 MEDDPAGHHNE-YEGIPMAEEYDYVHLKGMDKAQGSRPPDQ----ACTGDPEL----PER 411
PAG E + +P + ++V G G+ P + G+P L P+
Sbjct: 2495 PAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQP 2554
Query: 412 GMPAP 416
G+P P
Sbjct: 2555 GLPPP 2559
Score = 47.4 bits (111), Expect = 4e-05
Identities = 54/185 (29%), Positives = 73/185 (39%), Gaps = 38/185 (20%)
Query: 188 YDVPLTPKPPAEL--EP---DLEWEGGREPG---PPIYAAPSNLKRASALLNLYEAPEEL 239
Y+V L P+ PA EP + E GG+E G P LK+ A+L Y +L
Sbjct: 4815 YEV-LFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQL 4873
Query: 240 LADGEGGGTDEGIYDVPLLGPEAPPSPEPPGA------LASHDQDTLAQLLARSPPPPHR 293
D+ L + P+PEPP +++ D L+ P PP
Sbjct: 4874 --------------DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS 4919
Query: 294 PRLPSAESLSRRPL---PALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP------PPRL 344
P PS S PL P P+ E P PSP+P + + R PP PPRL
Sbjct: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979
Query: 345 PGYGG 349
+ G
Sbjct: 4980 KKWKG 4984
Score = 43.1 bits (100), Expect = 7e-04
Identities = 66/297 (22%), Positives = 98/297 (32%), Gaps = 62/297 (20%)
Query: 73 KPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPT-SGPPAGPCPPSPDLIYKIP 131
+P LSP P SP P S + +PPP P T + PPA P +L Y
Sbjct: 905 EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPA--LSPLGELEYPFG 962
Query: 132 RASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPL-TRVAPQPPGEDDAPYDV 190
+ +P A L P S P + + P+ + P PG P
Sbjct: 963 AKGDSDPESPLAA--------PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014
Query: 191 PLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDE 250
L P + P L+ + PP +P L
Sbjct: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL--------------------------- 1047
Query: 251 GIYDVPLLGPEAPPSP-EPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPA 309
P + PSP P G + + A+L P P+ E + PLP+
Sbjct: 1048 ---------PLSVPSPLSPIGKVVGVSDE--AELHEMETEKVSEPECPALEPSATSPLPS 1096
Query: 310 LPVPEAPSPSPVPSPAPGRKGSIQDRPLP----------PPPPRLPGYGGPKVEGDP 356
P+ + P+P P+PA + + P P P + PG +++G P
Sbjct: 1097 -PMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSP 1152
Score = 39.7 bits (91), Expect = 0.007
Identities = 60/234 (25%), Positives = 79/234 (33%), Gaps = 38/234 (16%)
Query: 66 LPAGPAPKPSLSPASPAQPGSPY-PAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC---- 120
LP+ P + SP S + SP P P + V P P P S PP+ P
Sbjct: 2403 LPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP 2462
Query: 121 ---------PPSPDLIYKIPRASGTQLAA----------PRDALEVY---DVPPTALRVP 158
P P++ +K + T L A P L PP +R P
Sbjct: 2463 FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
Query: 159 SSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYA 218
+G + S P+ PQ GE VP PP + G PGP +
Sbjct: 2523 GTGAFVGTPS---PMRFTFPQAVGEPSLKPPVPQPGLPPPH---GINSHFG--PGPTL-G 2573
Query: 219 APSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGAL 272
P + A N + + L G T E PL P P P P G+L
Sbjct: 2574 KPQSTNYTVATGNFHPSGSPL--GPSSGSTGESYGLSPLRPPSVLPPPAPDGSL 2625
Score = 36.6 bits (83), Expect = 0.063
Identities = 80/327 (24%), Positives = 116/327 (35%), Gaps = 57/327 (17%)
Query: 69 GPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTS---GPPA---GPCPP 122
GP + + +PG P+ + D ++ +V P +P P+S PP G
Sbjct: 4047 GPLAIGTTPESMATEPGEVKPS---LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQ 4103
Query: 123 SPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPG 182
L++ S QL + + E VP L PS D P S + L + PQ P
Sbjct: 4104 QVSLLHTAGGGSHGQLGSGSSS-EASSVPHL-LAQPSVSLGDQPGSMTQNL--LGPQQPM 4159
Query: 183 EDDAPYDV--PLTPKPPAELEPD----------------LEWEGGREPGPPI-YAAPSNL 223
+ + P PKP L+ + +G P + + +P
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219
Query: 224 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLG-----PEAPPSPEPPGALASHDQD 278
++ ALL + + + G PL G P+ P P Q
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGP--------QT 4271
Query: 279 TLAQLLARSPPPPHRPRLPSAE-SLSRRPL--PALPVP------EAPSPSPVPSPAPGRK 329
Q L P P PRLP+ +LS P+ P P P E PS +PSP+
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331
Query: 330 GSIQDRPLPPPPPRLPGYGGPKVEGDP 356
Q LPP P P GP +E P
Sbjct: 4332 TEAQ---LPPTHPGTPKPQGPTLEPPP 4355
Score = 35.4 bits (80), Expect = 0.14
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 11/86 (12%)
Query: 260 PEAPPS-PEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSP 318
P+ PP P PPGAL++ L + PPP P+ P S P LP P
Sbjct: 4283 PQGPPRLPAPPGALSTGP--VLGPV--HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP 4338
Query: 319 SPVPSPAPGRKGSIQDRPLPPPPPRL 344
+ +P P Q L PPP R+
Sbjct: 4339 THPGTPKP------QGPTLEPPPGRV 4358
Score = 35.0 bits (79), Expect = 0.18
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 13/107 (12%)
Query: 269 PGALASHDQDTLAQLLARSP---PPPHRPRLPSAESLSRRPLPALPVPEAPSPSP---VP 322
PG D L+ L SP PP + +L R L A P PE PSP P P
Sbjct: 4865 PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA-PPPEEPSPPPSPLAP 4923
Query: 323 SPAPGRKGSIQDRPL-----PPPPPRLPGYGGPK-VEGDPEGREMED 363
SPA + + P PP P LP P+ P R E+
Sbjct: 4924 SPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
Score = 34.7 bits (78), Expect = 0.24
Identities = 35/119 (29%), Positives = 40/119 (33%), Gaps = 27/119 (22%)
Query: 70 PAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYK 129
PAP+P P Q Y SN D PPP P PP P PSP
Sbjct: 4884 PAPEP------PTQHSYTYNV---SNLDVRQLSAPPPEEP----SPPPSPLAPSP----- 4925
Query: 130 IPRASGTQLAAPRDAL-EVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAP 187
+ P + L E+ P VPS P + P R P GED P
Sbjct: 4926 --------ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRP 4976
Score = 34.3 bits (77), Expect = 0.31
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSG--PPAGPCPPSP 124
P PAP +LS P P P P E + +P P+ PT PP P P P
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346
Score = 29.6 bits (65), Expect = 7.7
Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 9/97 (9%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPP-----PARPCPTSGPPAGPCP 121
P P P PS SP +P P P S++ +PP P PT PP G
Sbjct: 4304 PVHPTPPPS----SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
Query: 122 PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVP 158
P+ + + G P D L P + VP
Sbjct: 4360 PAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVP 4396
Score = 29.6 bits (65), Expect = 7.7
Identities = 28/103 (27%), Positives = 36/103 (34%), Gaps = 15/103 (14%)
Query: 116 PAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASF-SHPLT 174
PA P Y + QL+AP PP P S PAS + PL
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAP---------PPEEPSPPPSPLAPSPASPPTEPLV 4934
Query: 175 RVAPQPPGEDDAPYDVPL-----TPKPPAELEPDLEWEGGREP 212
+ +P E P +PL + +P P E E R P
Sbjct: 4935 ELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 70.9 bits (172), Expect = 3e-12
Identities = 87/312 (27%), Positives = 119/312 (38%), Gaps = 58/312 (18%)
Query: 55 QGIVPANRVKLLPAGPAPKPS-------LSPASPAQPGSPY----PAPDHSNEDQEVYVV 103
Q +VP N V P P P P+ L PA P P P P P ++ Q + V
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA-PCAPSLPQFSAPPPPLKIHQVQHITQV 758
Query: 104 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 163
PP P P P P P + IP + T+ AP + PPT P P
Sbjct: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP---VVTQAAPPTP--TPPVPPA 813
Query: 164 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNL 223
+F P + + P PP P P PP L P + + P P+ PS +
Sbjct: 814 KKQPAF--PASYIPPSPP--------TPPVPVPPPTL-PKQQSFCAKPPPSPLSPVPSVV 862
Query: 224 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 283
K+ + + + P T + PL A +P+ P A+ + + + +
Sbjct: 863 KQ---IASQFPPPP----------TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909
Query: 284 LARSP--PPPHRPRLPSAESLSRRPLPALPVPEAP-------SPSPVPSPAPGRKGSIQD 334
SP PPP P SL P P PVP P SP+P S +PG+K S
Sbjct: 910 PVPSPDFPPP-----PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTS 964
Query: 335 RP---LPPPPPR 343
P PPP P+
Sbjct: 965 SPGGKKPPPTPQ 976
Score = 61.6 bits (148), Expect = 2e-09
Identities = 77/314 (24%), Positives = 111/314 (35%), Gaps = 41/314 (13%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPT-SGPPAGPCPP--- 122
P P PK ++P + +QP P P P PPP P P+ S P AG P
Sbjct: 608 PLSPQPK-IVTPYTASQPSPPLPPPPPPPPPPPP-PPPPPPPPLPSQSAPSAGSAAPMFV 665
Query: 123 SPDLIYKIPRAS---GTQLAAPRDALEVYD-------VPPTALRVPSSGPYDCPASFSHP 172
I ++ AS G P + VPP + VP P P +
Sbjct: 666 KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV-VPPPPPPPPPPTPGSA 724
Query: 173 LTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNL 232
+ ++ P P + P P +++ + P PP AP + L
Sbjct: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVT 784
Query: 233 YEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPH 292
AP P++ APP+P PP A A + SPP P
Sbjct: 785 IPAPTSTKTVA------------PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832
Query: 293 ----RPRLPSAESLSRRPLPALPVPEAPSPSPVPS-----PAPGRKGSIQDRPLPPPPPR 343
P LP +S +P P+ P +P PS V P P +++ +PL P P
Sbjct: 833 VPVPPPTLPKQQSFCAKPPPS---PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPAN 889
Query: 344 LPGYGGPKVEGDPE 357
+ P V+ P+
Sbjct: 890 VAPQSPPAVKAKPK 903
Score = 53.1 bits (126), Expect = 6e-07
Identities = 74/293 (25%), Positives = 101/293 (34%), Gaps = 42/293 (14%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGP-------PAGP 119
P P P P L P +P +P PAP + V P P P P PA
Sbjct: 765 PPPPIPAP-LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASY 823
Query: 120 CPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQ 179
PPSP P P+ PP+ L S + F P P
Sbjct: 824 IPPSPPT----PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP-----PT 874
Query: 180 PPGEDDAPYD-VP--LTPKPPAELEPDLEWEGGREPGP-PIYAAPSNLKRASALLNLYEA 235
PP + P VP + P+ P ++ +W+ P P P + P S+L+
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP---ESSLVFPPPP 931
Query: 236 PEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPR 295
P + A P P A P+P+ G+ T + + PP P R
Sbjct: 932 PSPVPAPP------------PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979
Query: 296 LPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP--PPRLPG 346
+ S + P P P ++ P P GS LPPP PP+ PG
Sbjct: 980 SIKSSSGAEHPEPKRPSVDSLVSKFTP---PAESGSPSKETLPPPAAPPK-PG 1028
Score = 50.4 bits (119), Expect = 4e-06
Identities = 81/342 (23%), Positives = 103/342 (30%), Gaps = 84/342 (24%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCP------------TSG 114
P P P P S P P SP PAP PP A P P TS
Sbjct: 914 PDFPPPPPESSLVFPPPPPSPVPAPPPPP--------PPTASPTPDKSGSPGKKTSKTSS 965
Query: 115 PPAGPCPPSPDLIYKIPRASGTQLAAPR----DALEVYDVPPTALRVPSSGPYDCPASFS 170
P PP+P I +SG + P+ D+L PP PS PA+
Sbjct: 966 PGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
Query: 171 HP----LTRVA----------------------------PQPPGEDDAPYDVPLTPKPPA 198
P L+ V P PP + D P P T P
Sbjct: 1026 KPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP 1085
Query: 199 ELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLL 258
+E + G P + P + + + P + T I + P +
Sbjct: 1086 PIEIPAVFSGNTSPKVAV-VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTM 1144
Query: 259 GPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSP 318
P P P + S LA L R + SLS R A P
Sbjct: 1145 ATVVPQVPTSPKSSLSVQPGFLADLNRTL----QRKSITRHGSLSSRMSRAEPT------ 1194
Query: 319 SPVPSPAPGRKGSIQDRPLPPPPPRL------PGYGGPKVEG 354
++ D LPPPPP L GYGG + G
Sbjct: 1195 -----------ATMDDMALPPPPPELLSDQQKAGYGGSHISG 1225
Score = 39.3 bits (90), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 14/63 (22%)
Query: 288 PPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGY 347
PP +P++ + + S+ P P LP P P P P P P PPPPP LP
Sbjct: 607 PPLSPQPKIVTPYTASQ-PSPPLPPPPPPPPPPPPPP-------------PPPPPPLPSQ 652
Query: 348 GGP 350
P
Sbjct: 653 SAP 655
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 69.7 bits (169), Expect = 7e-12
Identities = 82/298 (27%), Positives = 108/298 (36%), Gaps = 56/298 (18%)
Query: 67 PAGPAPKPSLSPASPAQ-PGSPYPAPDHSNEDQEVYVVPPPARP-CPTSGPPAGPCPPSP 124
PA KPS P+SP Q + +P N+ E PPP P T+ PP P P P
Sbjct: 316 PAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEP---PPPKIPKIETTHPPLPPAHPPP 372
Query: 125 DLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGED 184
D K P A+ A P ++ D+P + P+ HP P P
Sbjct: 373 DR--KPPLAAALGEAEPPGPVDATDLPKVQIPPPA-----------HPAPVHQPPP---- 415
Query: 185 DAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS----ALLNLYEAPEELL 240
P+ P P PP+ + G + S +K AL Y P L
Sbjct: 416 -LPHRPP--PPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP 472
Query: 241 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHR------- 293
Y + P PP P PP AS + PPPP
Sbjct: 473 ------------YHPHVYPPNPPPPPVPPPP-ASFPPPAIPPPTPGYPPPPPTYNPNFPP 519
Query: 294 --PRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGG 349
PRLP ++ P P L +P P+ P P+ PG + + P P PPP +P GG
Sbjct: 520 PPPRLPPTHAVPPHPPPGLGLP--PASYPPPAVPPGGQPPV---PPPIPPPGMPPVGG 572
Score = 40.4 bits (93), Expect = 0.004
Identities = 67/287 (23%), Positives = 97/287 (33%), Gaps = 52/287 (18%)
Query: 74 PSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPR- 132
PSL P +P P P S+E + P +P P P PSP PR
Sbjct: 277 PSLQP-TPQVPQVQQSQPSQSSEPSQPQQ-KDPQQPAQQQQPAQQPKKPSPQP--SSPRQ 332
Query: 133 ASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP---GEDDAPYD 189
+ +P++ + + PP ++P P +HP P GE + P
Sbjct: 333 VKRAVVVSPKEENKAAEPPPP--KIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGP 390
Query: 190 VPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTD 249
V T P ++ P +P PP+ P +S + + + +G
Sbjct: 391 VDATDLPKVQIPPPAHPAPVHQP-PPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQS 449
Query: 250 EGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPA 309
+ P G PP+ PP L H + +PPPP
Sbjct: 450 MMKTEGPSYGA-LPPAYGPPAHLPYHPH-----VYPPNPPPP------------------ 485
Query: 310 LPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDP 356
PVP P P+ P PA +PPP P GY P +P
Sbjct: 486 -PVP--PPPASFPPPA-----------IPPPTP---GYPPPPPTYNP 515
Score = 33.5 bits (75), Expect = 0.53
Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 260 PEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPS 319
P+ S + S Q Q A+ P +P+ PS + S R + V +
Sbjct: 286 PQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN 345
Query: 320 PVPSPAPGRKGSIQDR--PLP---PPPPRLPGYGGPKVEGDPEG 358
P P + I+ PLP PPP R P E +P G
Sbjct: 346 KAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPG 389
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 68.9 bits (167), Expect = 1e-11
Identities = 122/476 (25%), Positives = 169/476 (35%), Gaps = 87/476 (18%)
Query: 47 CLCSLHGQQGIVPANRVKLLPA--GPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVY--V 102
C+CS +G V + L A P P L S P P H + + V
Sbjct: 650 CVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPV 709
Query: 103 VPPPARPCPTS-GPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP--------- 152
+PPP+ P PT G PA P P L P Q+ AP+ + + VPP
Sbjct: 710 LPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLP---QVLAPQPVVPLQPVPPHLPPYLAPA 766
Query: 153 TALRVPSS-GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPK------PPAELEPDLE 205
+ + P+ P P + PL +V PQ P P P+TP PPA PDL
Sbjct: 767 SQVGAPAQLKPLQMPQAPLQPLAQVPPQMP---PIPVVPPITPLAGIDGLPPAL--PDLP 821
Query: 206 WEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPL--LGPEAP 263
PP Y +P+ + + A +P L + +P + P AP
Sbjct: 822 TATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAP 881
Query: 264 PS-----PEPPGALASHDQDTLAQLLARS--------------PPPPH-----------R 293
+ PPG A +AQL + PP PH +
Sbjct: 882 ATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQ 941
Query: 294 PRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGS--IQDRPLPPPPPRLPGYGGPK 351
P LP +L P P LP P PV P P R + +P+ PP P LP P
Sbjct: 942 PALPPQPTLP--PQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQ--PA 997
Query: 352 VEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPER 411
+ PE P H + P A + L P A ++P
Sbjct: 998 LPVRPE-------PLQPHLPEQAAPAATPGSQILL--------GHPAPYAVDVAAQVPTV 1042
Query: 412 GMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPP 467
+P P LSP P V+ +LL Q S + + A+V ++ + T PP
Sbjct: 1043 PVP-PAAVLSPPLPEVLLPAAPELL----PQFPSSLATVSASVQSVPTQTATLLPP 1093
Score = 50.4 bits (119), Expect = 4e-06
Identities = 83/335 (24%), Positives = 121/335 (36%), Gaps = 60/335 (17%)
Query: 110 CPTSGPPAGPCPPS--PDLIYKIPRASGTQLAAPRDALEVYDVPP---TALRVPSSGPYD 164
CP + PA P S P + +P + A +D L + P + + +GP +
Sbjct: 1316 CPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSN 1375
Query: 165 CPASFSHPLTRVAPQPPGEDDAPYD--VPLTPKPPAELEPDLEWEGGREPGPPIYAAPSN 222
P + PL AP P P D P T P GG PG P S
Sbjct: 1376 PPGAPPAPL---APSSPPVTALPQDGAAPATSTMPEPASGTASQAGG--PGTP-QGLTSE 1429
Query: 223 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 282
L+ + L +EAP + PL+ AP +P P A T
Sbjct: 1430 LETSQPLAETHEAPLAVQ---------------PLVVGLAPCTPAPEAA------STRDA 1468
Query: 283 LLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSP--------SPVPSP-----APGRK 329
R P PP P PS S + +P P P P+ S +PSP P +
Sbjct: 1469 SAPREPLPPPAPE-PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP 1527
Query: 330 GSIQDRPLPPPPPRLPGYGGPKVEGDPEGREM---EDDPAGHHNEYEGIPMAEEYDYVHL 386
S + PPPR+ D + R + E P + + + + D+
Sbjct: 1528 PSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDR-DFT-- 1584
Query: 387 KGMDKAQGSRPPDQACTGDPELPERGMPAPQEALS 421
++ +G +P + C GD LP P P+EA+S
Sbjct: 1585 --LEPLRGDQPRSEVCGGDLALP----PVPKEAVS 1613
Score = 50.1 bits (118), Expect = 5e-06
Identities = 81/336 (24%), Positives = 117/336 (34%), Gaps = 52/336 (15%)
Query: 65 LLPAGPAPKPSLSPASPAQ-------PGSPYPAPDHSNEDQEVYVVP--PPARPCPTSGP 115
+LP+ AP P SPA P Q PG+P P + +VP P P P
Sbjct: 839 ILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRT-------IVPNAPATIPLLAVAP 891
Query: 116 PAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTR 175
P + ++P A P+ A DVPP+ + P P
Sbjct: 892 PGVAALSIHSAVAQLPGQPVYPAAFPQMAPT--DVPPSPHHTVQNMRATPPQPALPPQPT 949
Query: 176 VAPQP--PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLY 233
+ PQP P + P L P+P +P L + P P + P+ R L
Sbjct: 950 LPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQP-- 1007
Query: 234 EAPEELLADGEGGGTDEGIYDVPL---LGPEAPPSPEPPGALASHDQDTLAQLLARSPPP 290
PE+ G + P + + P P PP A+ S L ++L + P
Sbjct: 1008 HLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS---PPLPEVLLPAAPE 1064
Query: 291 PHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKG-------------------S 331
P+ PS+ + + ++P A P P PG G +
Sbjct: 1065 L-LPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQA 1123
Query: 332 IQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAG 367
QD+P P P YGG V G+E+ D G
Sbjct: 1124 SQDKP-PGLPQSCESYGGSDV---TSGKELSDSCEG 1155
Score = 40.0 bits (92), Expect = 0.006
Identities = 101/471 (21%), Positives = 137/471 (29%), Gaps = 120/471 (25%)
Query: 60 ANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTS----GP 115
A++ L AGP+ P PA A P A +P PA + G
Sbjct: 1363 ASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGT 1422
Query: 116 PAG-----------------------------PCPPSPDLIYKIPRASGTQLAAPRDALE 146
P G PC P+P+ AS +APR+ L
Sbjct: 1423 PQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPE------AASTRDASAPREPLP 1476
Query: 147 VYDVPPTALRVPSSGPYDCPASFSHPL-----------TRVAPQPPGEDDAPYDVPLTPK 195
PP P SG PL T P PP P P+
Sbjct: 1477 ----PPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVP------PQ 1526
Query: 196 PPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYD- 254
PP+ LE D G P P + S +K L E + GT + D
Sbjct: 1527 PPSALESD-----GEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDR 1581
Query: 255 ----VPLLGPE-----------APPSPE-------------------PPGALASHDQDTL 280
PL G + PP P+ P A +Q T
Sbjct: 1582 DFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTS 1641
Query: 281 AQLLARSPPPP--HRPRLPSAESLSRRPLPALP--VPEAPSPSPVPSPAPGRKGSIQDRP 336
+ + A S P R + +P++P VP P+ V P G +
Sbjct: 1642 SSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARV-EPTDRDGGEAGESS 1700
Query: 337 LPPPPPRLPGYG---------GPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLK 387
PPP + G G + G P R + D + + D L
Sbjct: 1701 AEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLA 1760
Query: 388 GMDKAQGSRPPDQACTGDPELPE------RGMPAPQEALSPGEPLVVSTGD 432
+ S PPD P P+ R A + GEP+ +GD
Sbjct: 1761 SPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGD 1811
Score = 29.6 bits (65), Expect = 7.7
Identities = 49/190 (25%), Positives = 60/190 (31%), Gaps = 35/190 (18%)
Query: 242 DGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAES 301
DG+GG D P + PG A + A P P R ES
Sbjct: 2 DGDGGRRD------------VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVES 49
Query: 302 LSRRPLPALPVPEAPSPSPVPSPAPGR-----------KGSIQDRPLPPPPPRL---PGY 347
P P L EAP P P P P R + RP P P L PG
Sbjct: 50 DQEEP-PGLEAAEAPGPQP-PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGA 107
Query: 348 GGPKVEGDPE---GREMEDDPAGHHNEY----EGIPMAEEYDYVHLKGMDKAQGSRPPDQ 400
G + PE +E DP E +G P E V + A+ P +
Sbjct: 108 PGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGR 167
Query: 401 ACTGDPELPE 410
+PE E
Sbjct: 168 TRRDEPEEEE 177
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 66.6 bits (161), Expect = 6e-11
Identities = 86/313 (27%), Positives = 106/313 (33%), Gaps = 84/313 (26%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVV-PPPARPCPTSGPPAGPCPPSPD 125
P AP P L + + P P +P N + P RP + PP P PP P
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPP 185
Query: 126 LIYKIPRASG--TQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGE 183
L +P +S T L +P L ++P A VP + P P PP
Sbjct: 186 LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP---------------PPPPPP 230
Query: 184 DDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADG 243
P P PPA + D +K A L+L P L
Sbjct: 231 PPTP-----PPLPPASVLSD-----------------KAVKPQLAPLHLPPIPPPL---- 264
Query: 244 EGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLS 303
PLL P P + A + D A+ PP P P P A
Sbjct: 265 ------------PLLPPCGYPGLKAEPASPAQD--------AQEPPAPPPPLPPYASCSP 304
Query: 304 RRPLPALPVP------EAPSPSPVPSP---APGRKGSIQDRPLPPPPP-----------R 343
R LPA P+P E P P P SP AP +K Q P PP PP
Sbjct: 305 RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHG 364
Query: 344 LPGYGGPKVEGDP 356
PG GG K+ P
Sbjct: 365 RPGAGGGKLNPPP 377
Score = 48.1 bits (113), Expect = 2e-05
Identities = 69/265 (26%), Positives = 83/265 (31%), Gaps = 47/265 (17%)
Query: 52 HGQQGIVPANRVKLLPAGPAPKPSLSPASPAQPGS-----PYPAPDHSNEDQEVYVVPPP 106
HG P P P P P P P P S P +P + VV PP
Sbjct: 159 HGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPP 218
Query: 107 ARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCP 166
PC PP P P P L P AS A + L +PP +P P
Sbjct: 219 V-PCAPPPPPPPPPPTPPPL----PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPP---- 269
Query: 167 ASFSHPLTRVAPQPPGEDDAPYDVPLTPKPP-AELEPDLEWEGGREPG--------PPI- 216
+P + P P +D P P PP A P PG PP+
Sbjct: 270 --CGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLP 327
Query: 217 -----YAAPSNLKRASALLNLYEAP--------EELLADGEGGGTDEGIYDVPLLGPEAP 263
+ AP A AL P + G GGG L P AP
Sbjct: 328 PKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGG--------KLNPPPAP 379
Query: 264 PSPEPPGALASHDQDTLAQLLARSP 288
P+ P L+S Q A + P
Sbjct: 380 PARSPTTELSSKSQQATAWTPTQQP 404
Score = 43.9 bits (102), Expect = 4e-04
Identities = 78/318 (24%), Positives = 97/318 (30%), Gaps = 82/318 (25%)
Query: 102 VVPPPARPCPTSGPPAG-PCPPSPDLIYKIPRASGTQLAAP--RDALEVYDVPPTALRVP 158
V PPP P P PP G P PP P S + A P R AL T LR
Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR-- 60
Query: 159 SSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYA 218
+ R APQ E EGG +
Sbjct: 61 ---------KVTQINDRSAPQ------------------IESSKGTNKEGGGSANTRGAS 93
Query: 219 APSNLKR--ASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHD 276
P L A L A + +A G+ G P L + P P A
Sbjct: 94 TPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLG 153
Query: 277 QDTLAQLLARS-----------------PPPPHRPRLPSAESLS---------------- 303
+ A AR+ PPPP P LPS+ +
Sbjct: 154 NTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
Query: 304 --RRPLPALPVPEAPSPSPVPSPAP-----------GRKGSIQDRPLPPPPPRLP--GYG 348
P+P P P P P P P P P + + P+PPP P LP GY
Sbjct: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
Query: 349 GPKVEGDPEGREMEDDPA 366
G K E ++ ++ PA
Sbjct: 274 GLKAEPASPAQDAQEPPA 291
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 66.6 bits (161), Expect = 6e-11
Identities = 88/319 (27%), Positives = 120/319 (37%), Gaps = 47/319 (14%)
Query: 70 PAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPP---PARPCPTSG------PPAGPC 120
P P P P + +PG+P P E+ P PC + G PAGP
Sbjct: 434 PPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPE 493
Query: 121 PPSPDL---IYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCP----ASFSHPL 173
P L I + + T+L R+ ++ + SS P + S P
Sbjct: 494 KPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPG 553
Query: 174 TRVAPQPPGEDDAP---YDVPLTPKPPAELEPDLEWEGG----REPGPPIYAAPSNL--K 224
R P PP + D+ TP P ++ + +L+ G EPGPP P+ L +
Sbjct: 554 FR-GPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPP---DPAGLLSQ 609
Query: 225 RASALLNLY----EAPEELLADGEGGGTDEGIYD-----VPLLGPEAP-PSPEPPGALAS 274
A L+L E++ + G D I D P+ + P P PGA A
Sbjct: 610 TAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAV 669
Query: 275 HDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQD 334
LA L PPPP P LP P P P P P P P+P P P +
Sbjct: 670 AAPSVLAPTLP-LPPPPGFPPLPPP------PPPPPPQPGFPMPPPLPPPPPPPPPAHPA 722
Query: 335 RPLPPPP-PRLPGYGGPKV 352
+PPPP P PG P +
Sbjct: 723 VTVPPPPLPAPPGVPPPPI 741
Score = 47.4 bits (111), Expect = 4e-05
Identities = 109/416 (26%), Positives = 140/416 (33%), Gaps = 90/416 (21%)
Query: 71 APKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGP---PAGPCPPSPDLI 127
+P+P P SP AP+H D EV PP P P P P P PPSP
Sbjct: 1240 SPEPPAKEVEARPPLSPERAPEH---DLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP-- 1294
Query: 128 YKIPRASGTQLAAPRDALEVYDVPPTALRV--PSSGPYDCPASFSHPLTRVAPQPPGEDD 185
P T + P VPP L P P C + T P PG +
Sbjct: 1295 ---PEPETTDASHP-------SVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEP 1344
Query: 186 -----------APYDVPLTPKPPAELEPDLEWEG-GREPG-----PPIYAAPSNLKRASA 228
+ VP +P P L G R PG P ++ PS
Sbjct: 1345 PLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPS----GPL 1400
Query: 229 LLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEP---PGALASHDQ------DT 279
LL + P + G + + L P P P P P L + +
Sbjct: 1401 LLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPL 1460
Query: 280 LAQLLARSPPP----PHRPRLPSAESLS------RRPLPA------LPVPEAPSPSPVPS 323
L LA PPP P RPR LS R P A L +P P PS
Sbjct: 1461 LPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPS 1520
Query: 324 PAPGRKGSIQDR--PLPPPPPRLPGYGGPKVEGDP-EGREMEDDPAGHHNEYEGIP---- 376
R ++ R +P PPP LP P P E ++ + E IP
Sbjct: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR 1580
Query: 377 ----MAEEYDYVHLKGMDKAQG--SRPPDQACTGDPELPERGMPAPQEALSPGEPL 426
+ EEY + K++G RPP + + +P G P LSP +PL
Sbjct: 1581 GRDEVTEEY-----MELAKSRGPWRRPPKK--RHEDLVPPAGSP----ELSPPQPL 1625
Score = 44.3 bits (103), Expect = 3e-04
Identities = 73/322 (22%), Positives = 113/322 (35%), Gaps = 55/322 (17%)
Query: 69 GPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPP------------ 116
GP P S ++ + SP P PD S+ED+E+ + P RP P GPP
Sbjct: 556 GPTPPSSRPSSTGLEDISPTPLPD-SDEDEELDLGLGP-RPPPEPGPPDPAGLLSQTAEV 613
Query: 117 ----AGPCPPSPDLIYKIPRASGTQL-----AAPRDALEVYDVPPTALRVPSSGPYDCPA 167
G P+ + + + ++SG + P + D P + P + P+
Sbjct: 614 ALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPS 673
Query: 168 SFS-----------HPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPI 216
+ PL P PP + P PL P PP P P PP+
Sbjct: 674 VLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPP---PPPPAHPAVTVPPPPL 730
Query: 217 YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHD 276
AP + L L P G++ V + + G S
Sbjct: 731 -PAPPGVPPPPILPPLPPFP-------------PGLFPVMQVDMSHVLGGQWGGMPMSFQ 776
Query: 277 QDT--LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQD 334
T L++L+ P+ P + +A + + L + +P P + + PGR
Sbjct: 777 MQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGR--GQHW 834
Query: 335 RPLPPPPPRLPGYGGPKVEGDP 356
PLP P +P G + DP
Sbjct: 835 PPLPKFDPSVPPPGYMPRQEDP 856
Score = 40.0 bits (92), Expect = 0.006
Identities = 21/58 (36%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSP 124
P P P+P P P P P P H VPPP P P PP PP P
Sbjct: 694 PPPPPPQPGFPMPPPLPPPPPPPPPAHP-----AVTVPPPPLPAPPGVPPPPILPPLP 746
Score = 38.9 bits (89), Expect = 0.013
Identities = 58/212 (27%), Positives = 77/212 (36%), Gaps = 44/212 (20%)
Query: 65 LLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC---P 121
L P P P P P P P P P P + +PPP P P PPA P P
Sbjct: 675 LAPTLPLPPPPGFPPLPPPPPPPPPQPG--------FPMPPPLPPPPPPPPPAHPAVTVP 726
Query: 122 PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP 181
P P +P G VPP + +P P+ P F ++
Sbjct: 727 PPP-----LPAPPG--------------VPPPPI-LPPLPPFP-PGLFPVMQVDMSHVLG 765
Query: 182 GEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS-ALLNL--YEAPEE 238
G+ +P++ + ++ L G P PP AA + A +NL Y P
Sbjct: 766 GQWGG---MPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFS 822
Query: 239 LLADGEGGGTDEGIYDVPLLGPEAPPSPEPPG 270
L G G G + PL P+ PS PPG
Sbjct: 823 LSNSGPG----RGQHWPPL--PKFDPSVPPPG 848
Score = 36.6 bits (83), Expect = 0.063
Identities = 74/332 (22%), Positives = 106/332 (31%), Gaps = 75/332 (22%)
Query: 139 AAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP---------GEDDAPYD 189
A P+D+ PP A P+ G + + P+ P P D +
Sbjct: 370 AQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFR 429
Query: 190 VPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTD 249
P P EP + + G PGPP +N +PE D G T
Sbjct: 430 RAPAPPPLPPAEPLAKEKPGTPPGPP--PPDTNSMELGGRPTFGWSPEP--CDSPGTPTL 485
Query: 250 EGIYDVPLLGPEAPPSPEPPG-------------------ALASHDQDTLAQL------L 284
E +P PE P L D DT Q+
Sbjct: 486 E----------SSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISS 535
Query: 285 ARSPPPPHRPRLPSAESLSRRPLPALPVP-----EAPSPSPVPSPAPGRKGSIQDRPLPP 339
+ S P P +++ R P P P E SP+P+P + + P PP
Sbjct: 536 SSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPP 595
Query: 340 PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD 399
P P P DP G + + P +E+ MD+ Q S D
Sbjct: 596 PEPGPP---------DPAGLLSQTAEVALDLVGDRTPTSEK--------MDEGQQSSGED 638
Query: 400 QACTGDPELPERGMPAPQEALSPGEPLVVSTG 431
+ D E+P AP + +P+VV+ G
Sbjct: 639 MEIS-DDEMPS----APITSADCPKPMVVTPG 665
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 66.2 bits (160), Expect = 7e-11
Identities = 80/296 (27%), Positives = 99/296 (33%), Gaps = 38/296 (12%)
Query: 67 PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVP-PPARPCPTSG-PPAGPCPPSP 124
P GP P+ P P PG P P ++ + P P P P G P GP PP P
Sbjct: 57 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-PPPP 115
Query: 125 DLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGED 184
P G + P + PP + S P P P + QP G
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDK--SRSPRSPPGKPQGPPPQGGNQPQGPP 173
Query: 185 DAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGE 244
P P P P +P G+ GPP S ++ P +
Sbjct: 174 PPP-GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPP-------Q 225
Query: 245 GGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE---- 300
GG +G P P P P P G + PPPP +P+ P A+
Sbjct: 226 GGNQPQG----PPPPPGKPQGPPPQGGNK-----------PQGPPPPGKPQGPPAQGGSK 270
Query: 301 SLSRRPLPAL----PVPEAPSPSPVPSPAPGRKGSIQDRPL--PPPPPRLPGYGGP 350
S S R P P E +P P PA G Q P P PPR P G P
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326
Score = 59.7 bits (143), Expect = 7e-09
Identities = 84/347 (24%), Positives = 110/347 (31%), Gaps = 67/347 (19%)
Query: 92 DHSNEDQEVYVVPPPARPCPTSG-PPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDV 150
D S E+ + P P P G P GP PP P P G + P +
Sbjct: 22 DVSQEESPSLIAGNPQGPSPQGGNKPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 80
Query: 151 PPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGR 210
PP + S P P P + QP G P P P P P G+
Sbjct: 81 PPQGDK--SRSPRSPPGKPQGPPPQGGNQPQGPPPPP-GKPQGPPPQGGNRPQGPPPPGK 137
Query: 211 EPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPG 270
GPP S R+ P+ GG +G P P P P P G
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQ-------GGNQPQG----PPPPPGKPQGPPPQG 186
Query: 271 ALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKG 330
+ PPPP +P+ P + R + SP P P + G
Sbjct: 187 GKKP-----------QGPPPPGKPQGPPPQGDKSR--------SSQSPPGKPQGPPPQGG 227
Query: 331 SIQDRPLPPP--PPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG 388
+ P PPP P P GG K +G P + + PA +G
Sbjct: 228 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPA--------------------QG 267
Query: 389 MDKAQGSRPPDQACTGDPEL----------PERGMPAPQEALSPGEP 425
K+Q +R P G P+ P G P +A G+P
Sbjct: 268 GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 314
Score = 36.2 bits (82), Expect = 0.082
Identities = 34/127 (26%), Positives = 47/127 (37%), Gaps = 10/127 (7%)
Query: 300 ESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGR 359
E +S+ P+L PSP P +P PPP GP G P+G
Sbjct: 21 EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 80
Query: 360 EMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPE-LPERGMPAPQE 418
+ D + G P +G ++ QG PP G P+ P +G PQ
Sbjct: 81 PPQGDKSRSPRSPPGKPQGPP-----PQGGNQPQGPPPP----PGKPQGPPPQGGNRPQG 131
Query: 419 ALSPGEP 425
PG+P
Sbjct: 132 PPPPGKP 138
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 64.7 bits (156), Expect = 2e-10
Identities = 66/236 (27%), Positives = 85/236 (36%), Gaps = 61/236 (25%)
Query: 146 EVYDVPPTALRVPSSGPYDCPASFSHPL-----TRVAPQP-PGEDDAPYDVPLTPKPPAE 199
E+ + A+ VP S P P + PL T + P P PG+ P P P PP
Sbjct: 552 EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP 611
Query: 200 LEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLG 259
L PG ++P +L +A+ P L D
Sbjct: 612 L-----------PGGVCISSPPSLPGGTAI----SPPPPLSGDAT--------------- 641
Query: 260 PEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPS 319
PP P P + +L A PPPP LP + +R P P P+P +
Sbjct: 642 --IPPPPPLPEGVGIPSPSSLPGGTAIPPPPP----LPGS---ARIPPPPPPLPGSAGIP 692
Query: 320 PVPSPAPGRKGSIQDRPLPPPPPRLPG----------YGGPKVEGDPEGREMEDDP 365
P P P PG G +PPPPP LPG GGP + P G M P
Sbjct: 693 PPPPPLPGEAG------MPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 742
Score = 53.5 bits (127), Expect = 5e-07
Identities = 78/288 (27%), Positives = 94/288 (32%), Gaps = 98/288 (34%)
Query: 74 PSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRA 133
PS+ +P P P P D + PPPA T+ PP P PP P
Sbjct: 565 PSVPSRAPVPPAPPLPG------DSGTIIPPPPAPGDSTTPPPPPPPPPPP--------- 609
Query: 134 SGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLT 193
PP V S P P T ++P PP DA +
Sbjct: 610 -----------------PPLPGGVCISSPPSLPGG-----TAISPPPPLSGDA----TIP 643
Query: 194 PKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIY 253
P PP EG P +PS+L +A+ P L G
Sbjct: 644 PPPPLP-------EGVGIP------SPSSLPGGTAI----PPPPPL----------PGSA 676
Query: 254 DVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVP 313
+P P PP P G PPPP P LP + P P P+P
Sbjct: 677 RIP---PPPPPLPGSAGI----------------PPPP--PPLPGEAGM---PPPPPPLP 712
Query: 314 EAPSPSPVPSPAPGRKGSIQDRP---LPPPPPRLPGYGGPKVEGDPEG 358
P P P P PG G P +PPPPP G+G P P G
Sbjct: 713 GGPG-IPPPPPFPGGPGIPPPPPGMGMPPPPPF--GFGVPAAPVLPFG 757
Score = 40.4 bits (93), Expect = 0.004
Identities = 48/175 (27%), Positives = 60/175 (34%), Gaps = 26/175 (14%)
Query: 58 VPANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPA 117
+P + ++P PAP S +P P P P P V + PP+ P T+ P
Sbjct: 579 LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG-----VCISSPPSLPGGTAISPP 633
Query: 118 GP------CPPSPDLI--YKIPRAS----GTQLAAPRDALEVYDVPPTALRVPSSGPYDC 165
P PP P L IP S GT + P +PP +P S
Sbjct: 634 PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 693
Query: 166 PASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAP 220
P PL A PP P + P PP P G P PP P
Sbjct: 694 PPP---PLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP------GIPPPPPGMGMP 739
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.134 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,828,951
Number of Sequences: 37866
Number of extensions: 2603780
Number of successful extensions: 35885
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 544
Number of HSP's successfully gapped in prelim test: 1862
Number of HSP's that attempted gapping in prelim test: 13942
Number of HSP's gapped (non-prelim): 13253
length of query: 561
length of database: 18,247,518
effective HSP length: 107
effective length of query: 454
effective length of database: 14,195,856
effective search space: 6444918624
effective search space used: 6444918624
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.