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Search of human proteins with 50284696
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50284696 IBR domain containing 2 [Homo sapiens]
(303 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50284696 IBR domain containing 2 [Homo sapiens] 660 0.0
gi|38045938 ring finger protein 144 [Homo sapiens] 353 1e-97
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 108 4e-24
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 108 4e-24
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 108 4e-24
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 108 4e-24
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 108 4e-24
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 103 2e-22
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 102 3e-22
gi|35493801 ring finger protein 19 [Homo sapiens] 99 4e-21
gi|35493782 ring finger protein 19 [Homo sapiens] 99 4e-21
gi|5453557 ariadne homolog 2 [Homo sapiens] 97 2e-20
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 94 1e-19
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 79 5e-15
gi|109150431 ring finger protein 31 [Homo sapiens] 75 9e-14
gi|22749145 ring finger protein 217 [Homo sapiens] 67 3e-11
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 66 3e-11
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 66 3e-11
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 65 6e-11
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 55 1e-07
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 55 1e-07
gi|169790973 parkin isoform 3 [Homo sapiens] 44 2e-04
gi|169790971 parkin isoform 2 [Homo sapiens] 44 2e-04
gi|169790969 parkin isoform 1 [Homo sapiens] 44 2e-04
gi|239048909 checkpoint with forkhead and ring finger domains is... 38 0.013
gi|239048905 checkpoint with forkhead and ring finger domains is... 38 0.013
gi|239048792 checkpoint with forkhead and ring finger domains is... 38 0.013
gi|239048907 checkpoint with forkhead and ring finger domains is... 38 0.013
gi|239048862 checkpoint with forkhead and ring finger domains is... 37 0.017
gi|78486540 DDB1 and CUL4 associated factor 15 [Homo sapiens] 36 0.037
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 660 bits (1702), Expect = 0.0
Identities = 303/303 (100%), Positives = 303/303 (100%)
Query: 1 MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQY 60
MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQY
Sbjct: 1 MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQY 60
Query: 61 MQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTW 120
MQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTW
Sbjct: 61 MQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTW 120
Query: 121 CPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRA 180
CPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRA
Sbjct: 121 CPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRA 180
Query: 181 LFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPC 240
LFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPC
Sbjct: 181 LFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPC 240
Query: 241 RNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDP 300
RNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDP
Sbjct: 241 RNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDP 300
Query: 301 STT 303
STT
Sbjct: 301 STT 303
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 353 bits (905), Expect = 1e-97
Identities = 161/286 (56%), Positives = 204/286 (71%), Gaps = 3/286 (1%)
Query: 10 LAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGC 69
+ T PT DLA PL++CKLCL E +++MTT+ +CQCIFCT CLKQY++L I+EG
Sbjct: 1 MTTTRYRPT-WDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGL 59
Query: 70 GSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTV 129
+ I+CPD C G LQE EI C+V + Q Y++L+FEREV DP RTWCP + CQ V
Sbjct: 60 ETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAV 119
Query: 130 CPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIV-LPTEHRALFGTDAE- 187
C + P V+C +C ++FCS CK +WH C ++ PI LP E A F + +
Sbjct: 120 CQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDD 179
Query: 188 APIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHS 247
APIK+CP C+VYIER+EGCAQMMCKNCKH FCWYCL++LD+D L HYDKGPCRNKLGHS
Sbjct: 180 APIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHS 239
Query: 248 RASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRG 293
RASV+W+RTQVVGI G G++ LV SP LLLA+P ++CC CK +G
Sbjct: 240 RASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSKG 285
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 108 bits (271), Expect = 4e-24
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 35/247 (14%)
Query: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
L C +C CE+ + EC+ ++C ACLK Y ++ IR+G + CP+ C + T
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVAT- 275
Query: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECP 146
++ LV + F Y RL + + L +CP CQ PV +PG + + C
Sbjct: 276 -PGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ--LPV-MQEPGCTMGI-CS 330
Query: 147 SCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDA-------------------- 186
SC+ FC+ C+ +H C+ + ++ + L +A
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 187 -------EAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDK-- 237
E K CP C IE+ +GC +M C C FCW C+ +L +H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 238 GPCRNKL 244
PC N+L
Sbjct: 451 SPCFNRL 457
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 108 bits (271), Expect = 4e-24
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 35/247 (14%)
Query: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
L C +C CE+ + EC+ ++C ACLK Y ++ IR+G + CP+ C + T
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVAT- 275
Query: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECP 146
++ LV + F Y RL + + L +CP CQ PV +PG + + C
Sbjct: 276 -PGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ--LPV-MQEPGCTMGI-CS 330
Query: 147 SCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDA-------------------- 186
SC+ FC+ C+ +H C+ + ++ + L +A
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 187 -------EAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDK-- 237
E K CP C IE+ +GC +M C C FCW C+ +L +H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 238 GPCRNKL 244
PC N+L
Sbjct: 451 SPCFNRL 457
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 108 bits (271), Expect = 4e-24
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 35/247 (14%)
Query: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
L C +C CE+ + EC+ ++C ACLK Y ++ IR+G + CP+ C + T
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVAT- 275
Query: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECP 146
++ LV + F Y RL + + L +CP CQ PV +PG + + C
Sbjct: 276 -PGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ--LPV-MQEPGCTMGI-CS 330
Query: 147 SCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDA-------------------- 186
SC+ FC+ C+ +H C+ + ++ + L +A
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 187 -------EAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDK-- 237
E K CP C IE+ +GC +M C C FCW C+ +L +H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 238 GPCRNKL 244
PC N+L
Sbjct: 451 SPCFNRL 457
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 108 bits (271), Expect = 4e-24
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 35/247 (14%)
Query: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
L C +C CE+ + EC+ ++C ACLK Y ++ IR+G + CP+ C + T
Sbjct: 91 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVAT- 149
Query: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECP 146
++ LV + F Y RL + + L +CP CQ PV +PG + + C
Sbjct: 150 -PGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ--LPV-MQEPGCTMGI-CS 204
Query: 147 SCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDA-------------------- 186
SC+ FC+ C+ +H C+ + ++ + L +A
Sbjct: 205 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 264
Query: 187 -------EAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDK-- 237
E K CP C IE+ +GC +M C C FCW C+ +L +H++
Sbjct: 265 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 324
Query: 238 GPCRNKL 244
PC N+L
Sbjct: 325 SPCFNRL 331
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 108 bits (271), Expect = 4e-24
Identities = 67/247 (27%), Positives = 107/247 (43%), Gaps = 35/247 (14%)
Query: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
L C +C CE+ + EC+ ++C ACLK Y ++ IR+G + CP+ C + T
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVAT- 275
Query: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECP 146
++ LV + F Y RL + + L +CP CQ PV +PG + + C
Sbjct: 276 -PGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ--LPV-MQEPGCTMGI-CS 330
Query: 147 SCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDA-------------------- 186
SC+ FC+ C+ +H C+ + ++ + L +A
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 187 -------EAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDK-- 237
E K CP C IE+ +GC +M C C FCW C+ +L +H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 238 GPCRNKL 244
PC N+L
Sbjct: 451 SPCFNRL 457
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 103 bits (256), Expect = 2e-22
Identities = 74/284 (26%), Positives = 115/284 (40%), Gaps = 24/284 (8%)
Query: 14 AENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPI 73
AE PG A + C LCL ++ L C C CL+ Y++L I E PI
Sbjct: 107 AEGGGPG----AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPI 161
Query: 74 TCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVA 133
+CP+ C + + P Y+ R + DP WCP DC
Sbjct: 162 SCPE--CSERLNPHDIRLLLADP-PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY 218
Query: 134 SSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSC-----RDSQPIVLPTEHRALFGTDAEA 188
+ E C +FC CK WH +C + +Q + + T+H + E+
Sbjct: 219 GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQES 278
Query: 189 ---PIKQCPVCRVY-IERNEG-CAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCR-- 241
IK CP C Y I+ N+G C M C C FCW C++ + + L + C
Sbjct: 279 GPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD---LHYLSPSGCTFW 335
Query: 242 -NKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCII 284
K + ++W ++G VG+ +IA + P +++ P +
Sbjct: 336 GKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYV 379
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 102 bits (255), Expect = 3e-22
Identities = 74/285 (25%), Positives = 115/285 (40%), Gaps = 25/285 (8%)
Query: 14 AENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPI 73
AE PG A + C LCL ++ L C C CL+ Y++L I E PI
Sbjct: 107 AEGGGPG----AEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPI 161
Query: 74 TCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVA 133
+CP+ C + + P Y+ R + DP WCP DC
Sbjct: 162 SCPE--CSERLNPHDIRLLLADP-PLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAY 218
Query: 134 SSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSC-----RDSQPIVLPTEHRALFGTDAEA 188
+ E C +FC CK WH +C + +Q + + T+H + E+
Sbjct: 219 GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQES 278
Query: 189 ----PIKQCPVCRVY-IERNEG-CAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCR- 241
IK CP C Y I+ N+G C M C C FCW C++ + + L + C
Sbjct: 279 GPADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD---LHYLSPSGCTF 335
Query: 242 --NKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCII 284
K + ++W ++G VG+ +IA + P +++ P +
Sbjct: 336 WGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYV 380
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 99.4 bits (246), Expect = 4e-21
Identities = 70/272 (25%), Positives = 109/272 (40%), Gaps = 22/272 (8%)
Query: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQ 87
I C LCL S D+ + C C CL+QY+++ I E + I+CP+ C
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPH 186
Query: 88 EAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147
+ + V + Y+ R + DP WCP DC +
Sbjct: 187 DIRLILSDDV-LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREG 245
Query: 148 CHLKFCSCCKDAWHAEVSC-----RDSQPIVLPTEHRALFGTDAEA-----PIKQCPVCR 197
C +FC CK WH +C +Q + L T + E+ IK CP C
Sbjct: 246 CGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCA 305
Query: 198 VY-IERNEG-CAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCR---NKLGHSRASVM 252
Y I+ N+G C M C C FCW C++ + + L + C K + ++
Sbjct: 306 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD---LHYLSPSGCTFWGKKPWSRKKKIL 362
Query: 253 WNRTQVVGILVGLGIIALVTSPLLLLASPCII 284
W +VG VG+ +IA + P +++ P +
Sbjct: 363 WQLGTLVGAPVGIALIAGIAIPAMIIGIPVYV 394
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 99.4 bits (246), Expect = 4e-21
Identities = 70/272 (25%), Positives = 109/272 (40%), Gaps = 22/272 (8%)
Query: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQ 87
I C LCL S D+ + C C CL+QY+++ I E + I+CP+ C
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPH 186
Query: 88 EAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147
+ + V + Y+ R + DP WCP DC +
Sbjct: 187 DIRLILSDDV-LMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREG 245
Query: 148 CHLKFCSCCKDAWHAEVSC-----RDSQPIVLPTEHRALFGTDAEA-----PIKQCPVCR 197
C +FC CK WH +C +Q + L T + E+ IK CP C
Sbjct: 246 CGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCA 305
Query: 198 VY-IERNEG-CAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCR---NKLGHSRASVM 252
Y I+ N+G C M C C FCW C++ + + L + C K + ++
Sbjct: 306 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD---LHYLSPSGCTFWGKKPWSRKKKIL 362
Query: 253 WNRTQVVGILVGLGIIALVTSPLLLLASPCII 284
W +VG VG+ +IA + P +++ P +
Sbjct: 363 WQLGTLVGAPVGIALIAGIAIPAMIIGIPVYV 394
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 96.7 bits (239), Expect = 2e-20
Identities = 60/209 (28%), Positives = 87/209 (41%), Gaps = 7/209 (3%)
Query: 17 PTPGDLAPAPLITCKLCLCEQSLDKMTTLQ-ECQCIFCTACLKQYMQLAIREGCGSPITC 75
P P P +C Q + K L CQ FC +C +Q+ + +++G G ++C
Sbjct: 124 PNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSC 183
Query: 76 PDMVCLNHGTLQEAEIACLVPVDQF-QLYQRLKFEREVHLDPYRTWCPVADCQTVCPVAS 134
C E + L+P ++ + Y+R F V CP ADC V V
Sbjct: 184 MAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQE 241
Query: 135 SDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCP 194
+ V+C C+ FC C+ +HA C + + + A K CP
Sbjct: 242 PRARR---VQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCP 298
Query: 195 VCRVYIERNEGCAQMMCKNCKHTFCWYCL 223
C + IE+N GC M C CKH FCW CL
Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCL 327
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 94.0 bits (232), Expect = 1e-19
Identities = 62/198 (31%), Positives = 88/198 (44%), Gaps = 11/198 (5%)
Query: 30 CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAI-REGCGSPITCPDMVCLNHGTLQE 88
C++C T L EC FC C +Y+ I EG G I+CP C + +
Sbjct: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGC--DILVDD 242
Query: 89 AEIACLVPVDQFQL-YQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147
+ L+ + +L YQ L V + WCP DC V V D +PV +C
Sbjct: 243 NTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPD-AKPVRCKCGR 301
Query: 148 CHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCA 207
+FC C + WH V C+ + + + + A K+CP C V IE++ GC
Sbjct: 302 ---QFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCN 358
Query: 208 QMMCK--NCKHTFCWYCL 223
M+C+ NCK FCW CL
Sbjct: 359 HMVCRNQNCKAEFCWVCL 376
>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
sapiens]
Length = 1089
Score = 79.0 bits (193), Expect = 5e-15
Identities = 62/233 (26%), Positives = 92/233 (39%), Gaps = 32/233 (13%)
Query: 18 TPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPD 77
+PGDL + C +C+C S+ + C FC C + ++ L I+EG I CP
Sbjct: 324 SPGDLDTS---LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPA 380
Query: 78 MVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPV---AS 134
C + I +V + + Y + + V +P WCP C + S
Sbjct: 381 YDCFQ--LVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGS 438
Query: 135 SDPGQPVL---------VECPSCHLKFCSCCKDAWHAEVSC---RDSQPIVLPTEHRALF 182
+ G L V+C HL FC C H C ++ + + L
Sbjct: 439 NTSGSDTLSFPLLRAPAVDCGKGHL-FCWECLGEAHEPCDCQTWKNWLQKITEMKPEELV 497
Query: 183 GT-----DAEAPI------KQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQ 224
G DA + K C C+ I++NEGC M C CK+ FCW CL+
Sbjct: 498 GVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLE 550
>gi|109150431 ring finger protein 31 [Homo sapiens]
Length = 1072
Score = 74.7 bits (182), Expect = 9e-14
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 22/209 (10%)
Query: 30 CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIRE---------GCGSPITCPDMVC 80
C +C ++M L C+C C C +Q+ +A++E CG P D
Sbjct: 699 CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQL 758
Query: 81 LNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQP 140
L++ + + ++ + D + L+ + E + DP WC C +
Sbjct: 759 LSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC------AQCSFGFIYEREQ 812
Query: 141 VLVECPSCHLKFCSCCKDAW---HAEVSCRDSQ--PIVLPTEHRAL-FGTDAEAPIKQCP 194
+ CP CH FC CK W H SC D Q + E++A + CP
Sbjct: 813 LEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCP 872
Query: 195 VCRV-YIERNEGCAQMMCKNCKHTFCWYC 222
C+ Y GC C C+H FC C
Sbjct: 873 KCKFSYALARGGCMHFHCTQCRHQFCSGC 901
Score = 30.0 bits (66), Expect = 2.6
Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 7/85 (8%)
Query: 98 DQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCK 157
D QL + RE+ P T C + S PG + CPSC C C
Sbjct: 185 DMLQLSEFDPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGT---LHCPSCKQALCPACD 241
Query: 158 DAWHAEVS----CRDSQPIVLPTEH 178
+H S R + P VL H
Sbjct: 242 HLFHGHPSRAHHLRQTLPGVLQGTH 266
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 66.6 bits (161), Expect = 3e-11
Identities = 25/80 (31%), Positives = 41/80 (51%)
Query: 143 VECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIER 202
++CP+C +C C WH V+C++ + H A + ++CP C+++I+R
Sbjct: 81 IQCPTCQFVWCFKCHSPWHEGVNCKEYKKGDKLLRHWASEIEHGQRNAQKCPKCKIHIQR 140
Query: 203 NEGCAQMMCKNCKHTFCWYC 222
EGC M C C FC+ C
Sbjct: 141 TEGCDHMTCSQCNTNFCYRC 160
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
isoform 1 [Homo sapiens]
Length = 468
Score = 66.2 bits (160), Expect = 3e-11
Identities = 48/202 (23%), Positives = 79/202 (39%), Gaps = 20/202 (9%)
Query: 30 CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP--DMVCLNHGTLQ 87
C +C + + L+EC FC CL Q IR + ++CP D G L
Sbjct: 240 CPVCYSVLAPGEAVVLRECLHTFCRECL----QGTIRNSQEAEVSCPFIDNTYSCSGKLL 295
Query: 88 EAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147
E EI L+ + +Q + L + + C DC+ C D + CP
Sbjct: 296 EREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWC-FFEDDVNE---FTCPV 351
Query: 148 CHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIK---------QCPVCRV 198
C C CK A H +++C++ Q + + +K +CP C++
Sbjct: 352 CFHVNCLLCK-AIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQI 410
Query: 199 YIERNEGCAQMMCKNCKHTFCW 220
+++ +GC + C C CW
Sbjct: 411 VVQKKDGCDWIRCTVCHTEICW 432
Score = 30.4 bits (67), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 3/33 (9%)
Query: 192 QCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQ 224
+CPVC + E ++ + C HTFC CLQ
Sbjct: 239 ECPVCYSVLAPGEA---VVLRECLHTFCRECLQ 268
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 66.2 bits (160), Expect = 3e-11
Identities = 48/202 (23%), Positives = 79/202 (39%), Gaps = 20/202 (9%)
Query: 30 CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP--DMVCLNHGTLQ 87
C +C + + L+EC FC CL Q IR + ++CP D G L
Sbjct: 282 CPVCYSVLAPGEAVVLRECLHTFCRECL----QGTIRNSQEAEVSCPFIDNTYSCSGKLL 337
Query: 88 EAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPS 147
E EI L+ + +Q + L + + C DC+ C D + CP
Sbjct: 338 EREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWC-FFEDDVNE---FTCPV 393
Query: 148 CHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIK---------QCPVCRV 198
C C CK A H +++C++ Q + + +K +CP C++
Sbjct: 394 CFHVNCLLCK-AIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQI 452
Query: 199 YIERNEGCAQMMCKNCKHTFCW 220
+++ +GC + C C CW
Sbjct: 453 VVQKKDGCDWIRCTVCHTEICW 474
Score = 30.4 bits (67), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 3/33 (9%)
Query: 192 QCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQ 224
+CPVC + E ++ + C HTFC CLQ
Sbjct: 281 ECPVCYSVLAPGEA---VVLRECLHTFCRECLQ 310
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 65.5 bits (158), Expect = 6e-11
Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 27/211 (12%)
Query: 30 CKLCL----CEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGT 85
C +C+ C+ L + + C C +C +Y+ I + TCP C T
Sbjct: 2070 CPVCVSPLGCDDDLPSLCCMHYC----CKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPT 2125
Query: 86 LQEAEIACLVPVDQ-FQLYQRLKFEREVHLDPYRTWCPVAD-CQTV-------CPVASSD 136
A I +V + Y++ V TWC C + C S
Sbjct: 2126 --GAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSK 2183
Query: 137 PGQPVLVEC--PSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCP 194
G C P H W + D + ++H A + K+CP
Sbjct: 2184 CGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLIS------KRCP 2237
Query: 195 VCRVYIERNEGCAQMMCKNCKHTFCWYCLQN 225
C+ IE+NEGC M C C H FCW CL++
Sbjct: 2238 SCQAPIEKNEGCLHMTCAKCNHGFCWRCLKS 2268
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/225 (24%), Positives = 93/225 (41%), Gaps = 37/225 (16%)
Query: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
LI C+ C E +++T + +FC CL +Y Q A+ ++C + C +
Sbjct: 512 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTC--SF 568
Query: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVE-- 144
+E+ ++P Y K E EV AD CP S P L++
Sbjct: 569 PTSELEKVLPQTILYKYYERKAEEEVA-------AAYADELVRCPSCSF----PALLDSD 617
Query: 145 -----CPS--CHLKFCSCCKDAW--HAEVSCRDSQPIVLPTEHRALFGTDAE-----API 190
CP+ C + C C+ W H ++C + L + + T E A I
Sbjct: 618 VKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEE-----LAEKDDIKYRTSIEEKMTAARI 672
Query: 191 KQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDN-DIFLRH 234
++C C + ++EGC +M C+ C C+ C +++ D F +H
Sbjct: 673 RKCHKCGTGLIKSEGCNRMSCR-CGAQMCYLCRVSINGYDHFCQH 716
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/225 (24%), Positives = 93/225 (41%), Gaps = 37/225 (16%)
Query: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
LI C+ C E +++T + +FC CL +Y Q A+ ++C + C +
Sbjct: 569 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTC--SF 625
Query: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVE-- 144
+E+ ++P Y K E EV AD CP S P L++
Sbjct: 626 PTSELEKVLPQTILYKYYERKAEEEVA-------AAYADELVRCPSCSF----PALLDSD 674
Query: 145 -----CPS--CHLKFCSCCKDAW--HAEVSCRDSQPIVLPTEHRALFGTDAE-----API 190
CP+ C + C C+ W H ++C + L + + T E A I
Sbjct: 675 VKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEE-----LAEKDDIKYRTSIEEKMTAARI 729
Query: 191 KQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDN-DIFLRH 234
++C C + ++EGC +M C+ C C+ C +++ D F +H
Sbjct: 730 RKCHKCGTGLIKSEGCNRMSCR-CGAQMCYLCRVSINGYDHFCQH 773
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 15/90 (16%)
Query: 148 CHLKFCSCCKDAWH-----AEVSCRDSQPIVLPTEHRALFGTDAEAPIKQ--------CP 194
C FC CK+A+H A + + RA EA K+ CP
Sbjct: 211 CGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCP 270
Query: 195 VCRVYIERNEGCAQMMC--KNCKHTFCWYC 222
C V +E+N GC M C C+ +CW C
Sbjct: 271 RCHVPVEKNGGCMHMKCPQPQCRLEWCWNC 300
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 15/90 (16%)
Query: 148 CHLKFCSCCKDAWH-----AEVSCRDSQPIVLPTEHRALFGTDAEAPIKQ--------CP 194
C FC CK+A+H A + + RA EA K+ CP
Sbjct: 332 CGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCP 391
Query: 195 VCRVYIERNEGCAQMMC--KNCKHTFCWYC 222
C V +E+N GC M C C+ +CW C
Sbjct: 392 RCHVPVEKNGGCMHMKCPQPQCRLEWCWNC 421
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 15/90 (16%)
Query: 148 CHLKFCSCCKDAWH-----AEVSCRDSQPIVLPTEHRALFGTDAEAPIKQ--------CP 194
C FC CK+A+H A + + RA EA K+ CP
Sbjct: 360 CGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCP 419
Query: 195 VCRVYIERNEGCAQMMC--KNCKHTFCWYC 222
C V +E+N GC M C C+ +CW C
Sbjct: 420 RCHVPVEKNGGCMHMKCPQPQCRLEWCWNC 449
>gi|239048909 checkpoint with forkhead and ring finger domains
isoform 5 [Homo sapiens]
Length = 572
Score = 37.7 bits (86), Expect = 0.013
Identities = 56/245 (22%), Positives = 79/245 (32%), Gaps = 62/245 (25%)
Query: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP-DMVCLNH--- 83
+TC +C+ L +LQ C FC AC +M+ R CP + +C NH
Sbjct: 210 LTC--IICQDLLHDCVSLQPCMHTFCAACYSGWME---RSSLCPTCRCPVERICKNHILN 264
Query: 84 -----------------GTLQEAEIACLVPVDQFQLYQRLKFEREVH------------- 113
+Q + + D Q R F E
Sbjct: 265 NLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDS 324
Query: 114 -----LDPYRT--WCPVADCQTV----CPVASSDPGQP-VLVECPSCHLKFCSCCKD--- 158
PY CP Q CP +PG P L + PS + + +D
Sbjct: 325 ESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALGDAPSTSVSLTTAVQDYVC 384
Query: 159 ---AWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVC-RVYIERNEGCAQMMCKNC 214
HA +C QP+ + RA D +QC VC + + GC + C C
Sbjct: 385 PLQGSHALCTC-CFQPM---PDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGC 440
Query: 215 KHTFC 219
FC
Sbjct: 441 LAPFC 445
>gi|239048905 checkpoint with forkhead and ring finger domains
isoform 3 [Homo sapiens]
Length = 652
Score = 37.7 bits (86), Expect = 0.013
Identities = 56/245 (22%), Positives = 79/245 (32%), Gaps = 62/245 (25%)
Query: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP-DMVCLNH--- 83
+TC +C+ L +LQ C FC AC +M+ R CP + +C NH
Sbjct: 290 LTC--IICQDLLHDCVSLQPCMHTFCAACYSGWME---RSSLCPTCRCPVERICKNHILN 344
Query: 84 -----------------GTLQEAEIACLVPVDQFQLYQRLKFEREVH------------- 113
+Q + + D Q R F E
Sbjct: 345 NLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDS 404
Query: 114 -----LDPYRT--WCPVADCQTV----CPVASSDPGQP-VLVECPSCHLKFCSCCKD--- 158
PY CP Q CP +PG P L + PS + + +D
Sbjct: 405 ESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALGDAPSTSVSLTTAVQDYVC 464
Query: 159 ---AWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVC-RVYIERNEGCAQMMCKNC 214
HA +C QP+ + RA D +QC VC + + GC + C C
Sbjct: 465 PLQGSHALCTC-CFQPM---PDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGC 520
Query: 215 KHTFC 219
FC
Sbjct: 521 LAPFC 525
>gi|239048792 checkpoint with forkhead and ring finger domains
isoform 1 [Homo sapiens]
Length = 664
Score = 37.7 bits (86), Expect = 0.013
Identities = 56/245 (22%), Positives = 79/245 (32%), Gaps = 62/245 (25%)
Query: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP-DMVCLNH--- 83
+TC +C+ L +LQ C FC AC +M+ R CP + +C NH
Sbjct: 302 LTC--IICQDLLHDCVSLQPCMHTFCAACYSGWME---RSSLCPTCRCPVERICKNHILN 356
Query: 84 -----------------GTLQEAEIACLVPVDQFQLYQRLKFEREVH------------- 113
+Q + + D Q R F E
Sbjct: 357 NLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDS 416
Query: 114 -----LDPYRT--WCPVADCQTV----CPVASSDPGQP-VLVECPSCHLKFCSCCKD--- 158
PY CP Q CP +PG P L + PS + + +D
Sbjct: 417 ESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALGDAPSTSVSLTTAVQDYVC 476
Query: 159 ---AWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVC-RVYIERNEGCAQMMCKNC 214
HA +C QP+ + RA D +QC VC + + GC + C C
Sbjct: 477 PLQGSHALCTC-CFQPM---PDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGC 532
Query: 215 KHTFC 219
FC
Sbjct: 533 LAPFC 537
>gi|239048907 checkpoint with forkhead and ring finger domains
isoform 4 [Homo sapiens]
Length = 623
Score = 37.7 bits (86), Expect = 0.013
Identities = 56/245 (22%), Positives = 79/245 (32%), Gaps = 62/245 (25%)
Query: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP-DMVCLNH--- 83
+TC +C+ L +LQ C FC AC +M+ R CP + +C NH
Sbjct: 261 LTC--IICQDLLHDCVSLQPCMHTFCAACYSGWME---RSSLCPTCRCPVERICKNHILN 315
Query: 84 -----------------GTLQEAEIACLVPVDQFQLYQRLKFEREVH------------- 113
+Q + + D Q R F E
Sbjct: 316 NLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDS 375
Query: 114 -----LDPYRT--WCPVADCQTV----CPVASSDPGQP-VLVECPSCHLKFCSCCKD--- 158
PY CP Q CP +PG P L + PS + + +D
Sbjct: 376 ESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALGDAPSTSVSLTTAVQDYVC 435
Query: 159 ---AWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVC-RVYIERNEGCAQMMCKNC 214
HA +C QP+ + RA D +QC VC + + GC + C C
Sbjct: 436 PLQGSHALCTC-CFQPM---PDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGC 491
Query: 215 KHTFC 219
FC
Sbjct: 492 LAPFC 496
>gi|239048862 checkpoint with forkhead and ring finger domains
isoform 2 [Homo sapiens]
Length = 663
Score = 37.4 bits (85), Expect = 0.017
Identities = 56/244 (22%), Positives = 78/244 (31%), Gaps = 61/244 (25%)
Query: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCP-DMVCLNH--- 83
+TC +C+ L +LQ C FC AC +M+ R CP + +C NH
Sbjct: 302 LTC--IICQDLLHDCVSLQPCMHTFCAACYSGWME---RSSLCPTCRCPVERICKNHILN 356
Query: 84 -----------------GTLQEAEIACLVPVDQFQLYQRLKFEREVH------------- 113
+Q + + D Q R F E
Sbjct: 357 NLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDS 416
Query: 114 -----LDPYRT--WCPVADCQTV----CPVASSDPGQP-VLVECPSCHLKFCS-----CC 156
PY CP Q CP +PG P L + PS + + C
Sbjct: 417 ESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALGDAPSTSVSLTTVQDYVCP 476
Query: 157 KDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVC-RVYIERNEGCAQMMCKNCK 215
HA +C QP+ + RA D +QC VC + + GC + C C
Sbjct: 477 LQGSHALCTC-CFQPM---PDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCL 532
Query: 216 HTFC 219
FC
Sbjct: 533 APFC 536
>gi|78486540 DDB1 and CUL4 associated factor 15 [Homo sapiens]
Length = 600
Score = 36.2 bits (82), Expect = 0.037
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 15/93 (16%)
Query: 76 PDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFER---------------EVHLDPYRTW 120
P+ CL HG + + + P FQ +LK ++ VH R++
Sbjct: 207 PNAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAGDRSF 266
Query: 121 CPVADCQTVCPVASSDPGQPVLVECPSCHLKFC 153
C + + CP+A + P +P E P FC
Sbjct: 267 CQILYDHSTCPLAPASPPEPQSPELPPALPSFC 299
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.138 0.479
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,889,090
Number of Sequences: 37866
Number of extensions: 670861
Number of successful extensions: 2668
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 2487
Number of HSP's gapped (non-prelim): 187
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.