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Search of human proteins with 49640011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
(2025 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens] 4098 0.0
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens] 4098 0.0
gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens] 122 3e-27
gi|116235456 ring finger protein 214 [Homo sapiens] 91 1e-17
gi|116235451 ring finger protein 214 [Homo sapiens] 91 1e-17
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 69 4e-11
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 67 2e-10
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 64 1e-09
gi|71061468 centromere protein E [Homo sapiens] 59 4e-08
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 59 5e-08
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 59 5e-08
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 59 5e-08
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 59 6e-08
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 58 1e-07
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l... 58 1e-07
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l... 58 1e-07
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 57 1e-07
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 57 1e-07
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 57 2e-07
gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein... 57 2e-07
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 57 2e-07
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein... 56 3e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 56 3e-07
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 56 3e-07
gi|28416946 myosin 18A isoform a [Homo sapiens] 56 3e-07
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 56 3e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 56 4e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 55 5e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 55 5e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 55 5e-07
>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 4098 bits (10628), Expect = 0.0
Identities = 2025/2025 (100%), Positives = 2025/2025 (100%)
Query: 1 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER 60
MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
Sbjct: 1 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER 60
Query: 61 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI 120
NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
Sbjct: 61 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI 120
Query: 121 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI 180
NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
Sbjct: 121 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI 180
Query: 181 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE 240
LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
Sbjct: 181 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE 240
Query: 241 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK 300
EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
Sbjct: 241 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK 300
Query: 301 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK 360
GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
Sbjct: 301 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK 360
Query: 361 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD 420
DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
Sbjct: 361 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD 420
Query: 421 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH 480
DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
Sbjct: 421 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH 480
Query: 481 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY 540
QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
Sbjct: 481 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY 540
Query: 541 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE 600
GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
Sbjct: 541 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE 600
Query: 601 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS 660
KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
Sbjct: 601 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS 660
Query: 661 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG 720
KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
Sbjct: 661 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG 720
Query: 721 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA 780
VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
Sbjct: 721 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA 780
Query: 781 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM 840
KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
Sbjct: 781 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM 840
Query: 841 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE 900
LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
Sbjct: 841 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE 900
Query: 901 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF 960
PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
Sbjct: 901 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF 960
Query: 961 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK 1020
SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
Sbjct: 961 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK 1020
Query: 1021 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF 1080
NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
Sbjct: 1021 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF 1080
Query: 1081 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE 1140
EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
Sbjct: 1081 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE 1140
Query: 1141 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY 1200
ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
Sbjct: 1141 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY 1200
Query: 1201 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN 1260
VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
Sbjct: 1201 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN 1260
Query: 1261 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY 1320
SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
Sbjct: 1261 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY 1320
Query: 1321 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN 1380
LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
Sbjct: 1321 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN 1380
Query: 1381 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN 1440
AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
Sbjct: 1381 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN 1440
Query: 1441 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ 1500
SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
Sbjct: 1441 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ 1500
Query: 1501 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ 1560
VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
Sbjct: 1501 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ 1560
Query: 1561 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE 1620
QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
Sbjct: 1561 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE 1620
Query: 1621 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY 1680
EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
Sbjct: 1621 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY 1680
Query: 1681 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV 1740
PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
Sbjct: 1681 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV 1740
Query: 1741 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE 1800
HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
Sbjct: 1741 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE 1800
Query: 1801 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS 1860
ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
Sbjct: 1801 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS 1860
Query: 1861 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV 1920
TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
Sbjct: 1861 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV 1920
Query: 1921 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK 1980
TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
Sbjct: 1921 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK 1980
Query: 1981 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR 2025
GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
Sbjct: 1981 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR 2025
>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 4098 bits (10628), Expect = 0.0
Identities = 2025/2025 (100%), Positives = 2025/2025 (100%)
Query: 1 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER 60
MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
Sbjct: 1 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER 60
Query: 61 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI 120
NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
Sbjct: 61 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI 120
Query: 121 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI 180
NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
Sbjct: 121 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI 180
Query: 181 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE 240
LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
Sbjct: 181 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE 240
Query: 241 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK 300
EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
Sbjct: 241 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK 300
Query: 301 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK 360
GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
Sbjct: 301 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK 360
Query: 361 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD 420
DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
Sbjct: 361 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD 420
Query: 421 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH 480
DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
Sbjct: 421 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH 480
Query: 481 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY 540
QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
Sbjct: 481 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY 540
Query: 541 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE 600
GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
Sbjct: 541 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE 600
Query: 601 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS 660
KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
Sbjct: 601 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS 660
Query: 661 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG 720
KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
Sbjct: 661 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG 720
Query: 721 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA 780
VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
Sbjct: 721 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA 780
Query: 781 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM 840
KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
Sbjct: 781 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM 840
Query: 841 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE 900
LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
Sbjct: 841 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE 900
Query: 901 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF 960
PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
Sbjct: 901 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF 960
Query: 961 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK 1020
SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
Sbjct: 961 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK 1020
Query: 1021 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF 1080
NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
Sbjct: 1021 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF 1080
Query: 1081 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE 1140
EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
Sbjct: 1081 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE 1140
Query: 1141 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY 1200
ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
Sbjct: 1141 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY 1200
Query: 1201 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN 1260
VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
Sbjct: 1201 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN 1260
Query: 1261 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY 1320
SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
Sbjct: 1261 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY 1320
Query: 1321 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN 1380
LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
Sbjct: 1321 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN 1380
Query: 1381 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN 1440
AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
Sbjct: 1381 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN 1440
Query: 1441 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ 1500
SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
Sbjct: 1441 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ 1500
Query: 1501 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ 1560
VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
Sbjct: 1501 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ 1560
Query: 1561 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE 1620
QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
Sbjct: 1561 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE 1620
Query: 1621 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY 1680
EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
Sbjct: 1621 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY 1680
Query: 1681 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV 1740
PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
Sbjct: 1681 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV 1740
Query: 1741 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE 1800
HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
Sbjct: 1741 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE 1800
Query: 1801 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS 1860
ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
Sbjct: 1801 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS 1860
Query: 1861 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV 1920
TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
Sbjct: 1861 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV 1920
Query: 1921 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK 1980
TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
Sbjct: 1921 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK 1980
Query: 1981 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR 2025
GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
Sbjct: 1981 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR 2025
>gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens]
Length = 1208
Score = 122 bits (307), Expect = 3e-27
Identities = 131/519 (25%), Positives = 219/519 (42%), Gaps = 82/519 (15%)
Query: 1524 TRDLEEKLKRHLEENKISKTELDWFLQDLEREIK----KWQQEKKEIQERLK---SLKKK 1576
T D E K L + +L + +D +R+++ +WQ+ + +I+++ K SL ++
Sbjct: 740 TTDYGETEKERLARQR-QLYKLHYQCEDFKRQLRTVTFRWQENQMQIKKKDKIIASLNQQ 798
Query: 1577 ----IKKVSNAS-EMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYE 1631
I KVS +++ + N+ K + +L + +S EK +E +K
Sbjct: 799 VAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRS-----QWEMEKHNLESTMKTYVSKLN 853
Query: 1632 ESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWE 1691
RA+ AEV L+ ++ + L+ E + L ++ ++ +++ + SW
Sbjct: 854 AETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSWN 913
Query: 1692 LFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGD 1751
+++V +I ++Q+ EQI +K G LS L VQ+ PE+L +
Sbjct: 914 AIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPP------PPPSPEILMQQFL- 966
Query: 1752 DGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAG 1811
G+ LV + + + P P + GQP A +TG
Sbjct: 967 -GRPLVKESFF-----------RPILTVPQMPAVCPGVV---SATGQPRAPLMTG----- 1006
Query: 1812 QAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVR 1871
A + +PV D VPP RS S + I + L FP EL F++K++
Sbjct: 1007 -IAWALPAPVGDA---VPPSAGLRSDPSIMN-WERITDRLKTAFPQQTRKELTDFLRKLK 1061
Query: 1872 SKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTY----------EPSSATPVT 1921
SLS L+ DEIV ++++ I KK + GK +P +A P
Sbjct: 1062 DAYGKSLSELTFDEIVCKISQFI---DPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPK 1118
Query: 1922 RS-----SQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGH 1976
+ SQG + A +P + ++ E C ICHE +N+ VL C H
Sbjct: 1119 PAWRPLTSQGPATWEGASNPDEEEEEEEP-----------CVICHENLSPENLSVLPCAH 1167
Query: 1977 KYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQ 2015
K+H C + WL Q CP C+ LL EE P G PS+
Sbjct: 1168 KFHAQCIRPWLMQQGTCPTCRLHVLLPEEFP---GHPSR 1203
Score = 79.3 bits (194), Expect = 3e-14
Identities = 60/217 (27%), Positives = 97/217 (44%), Gaps = 9/217 (4%)
Query: 527 QLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQF----KRIIEHYPSEGLDCLAYCGI 582
Q+N+ +L +YG+A++ G + E+ +EAEN+F I E+ E L Y G
Sbjct: 128 QINIGYYLTLLFLYGVALTERG--KKEDYTEAENKFLVMKMMIQENEICENFMSLVYFGR 185
Query: 583 GKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECK 642
G + + R+ L F K+ I W + +E P K LL F++ +
Sbjct: 186 GLLRCAQKRYNGGLLEFHKSLQEIGDKND--HWFDIDPTEDEDLPTTFKDLLNNFIKTTE 243
Query: 643 FPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFND 702
+ IC Y C + I + + +KGF ++ C + C + FH CWKK K +
Sbjct: 244 SNIMKQTICSYLDCERSCEADI-LKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKYPG 302
Query: 703 KIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFE 739
+ D+ F CL C G + +++ G VK FE
Sbjct: 303 ENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFE 339
>gi|116235456 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 90.9 bits (224), Expect = 1e-17
Identities = 110/509 (21%), Positives = 197/509 (38%), Gaps = 91/509 (17%)
Query: 1550 QDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEM----YTQKNDGKEKEHE--LHLD 1603
QD+E+ + K E+ ++ER + + K ++V N ++ Q+ + + K H+ L
Sbjct: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Query: 1604 QSLEISNTLTNEKM----------------KIEEYIKKGKED------------------ 1629
Q + I T +K+ +IE+ +KG+ +
Sbjct: 280 QDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINR 339
Query: 1630 -YEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIR 1688
E +RA AE+ LE+ KE V KL+ E +AE L L P + S +
Sbjct: 340 NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYL---KSTPPTLETVRSK-Q 395
Query: 1689 SWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPES 1748
WE L+ V + + QF I+ ++NG++LS L ++ L P T + +
Sbjct: 396 EWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQP 455
Query: 1749 SGDDGQGLVTSASDVTGNHAALHRDP-----SVFSAGDSPGEAPSALLPGP----PPGQP 1799
S + S VT DP + + S PS+ LPG PG
Sbjct: 456 SPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLG 515
Query: 1800 EATQLTGPKRAGQAALSERSPVADRKQPVPPG------RAARSSQSPKKPFNSIIEHLSV 1853
GP A++ P PPG A P I+E L
Sbjct: 516 SLVSPHGPHMPPAASI-----------PPPPGLGGVKASAETPRPQPVDKLEKILEKLLT 564
Query: 1854 VFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYE 1913
FP N ++ ++++++ + +++GL+++E++Q V + + ++
Sbjct: 565 RFPQCNKAQMTNILQQIKTA-RTTMAGLTMEELIQLVAARLAEHER-------------V 610
Query: 1914 PSSATPVTRSSQGSPSVVVAPS-PKTKGQKAEDVPVRIALGASSCEI---CHEVFKSKNV 1969
+S P+ R P+ + S P P R + ++C++ C ++ + +
Sbjct: 611 AASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLMCQKLVQPSEL 670
Query: 1970 RVLKCGHKYHKGCFKQWLKGQS--ACPAC 1996
+ C H HK C K W + + CP C
Sbjct: 671 HPMACTHVLHKECIKFWAQTNTNDTCPFC 699
>gi|116235451 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 90.9 bits (224), Expect = 1e-17
Identities = 110/509 (21%), Positives = 197/509 (38%), Gaps = 91/509 (17%)
Query: 1550 QDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEM----YTQKNDGKEKEHE--LHLD 1603
QD+E+ + K E+ ++ER + + K ++V N ++ Q+ + + K H+ L
Sbjct: 220 QDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAI 279
Query: 1604 QSLEISNTLTNEKM----------------KIEEYIKKGKED------------------ 1629
Q + I T +K+ +IE+ +KG+ +
Sbjct: 280 QDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINR 339
Query: 1630 -YEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIR 1688
E +RA AE+ LE+ KE V KL+ E +AE L L P + S +
Sbjct: 340 NIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYL---KSTPPTLETVRSK-Q 395
Query: 1689 SWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPES 1748
WE L+ V + + QF I+ ++NG++LS L ++ L P T + +
Sbjct: 396 EWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQP 455
Query: 1749 SGDDGQGLVTSASDVTGNHAALHRDP-----SVFSAGDSPGEAPSALLPGP----PPGQP 1799
S + S VT DP + + S PS+ LPG PG
Sbjct: 456 SPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLG 515
Query: 1800 EATQLTGPKRAGQAALSERSPVADRKQPVPPG------RAARSSQSPKKPFNSIIEHLSV 1853
GP A++ P PPG A P I+E L
Sbjct: 516 SLVSPHGPHMPPAASI-----------PPPPGLGGVKASAETPRPQPVDKLEKILEKLLT 564
Query: 1854 VFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYE 1913
FP N ++ ++++++ + +++GL+++E++Q V + + ++
Sbjct: 565 RFPQCNKAQMTNILQQIKTA-RTTMAGLTMEELIQLVAARLAEHER-------------V 610
Query: 1914 PSSATPVTRSSQGSPSVVVAPS-PKTKGQKAEDVPVRIALGASSCEI---CHEVFKSKNV 1969
+S P+ R P+ + S P P R + ++C++ C ++ + +
Sbjct: 611 AASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLMCQKLVQPSEL 670
Query: 1970 RVLKCGHKYHKGCFKQWLKGQS--ACPAC 1996
+ C H HK C K W + + CP C
Sbjct: 671 HPMACTHVLHKECIKFWAQTNTNDTCPFC 699
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 69.3 bits (168), Expect = 4e-11
Identities = 42/122 (34%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Query: 228 IEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGD 287
++ E +K + N+ F + ++ AI +Y++AIE P N + YGNR+L +LRT + ALGD
Sbjct: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGD 84
Query: 288 GKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQ 347
RA L + KG+YR + LG++ AL+ K+ +D + K Q+ K+
Sbjct: 85 ATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDA-KMKYQECNKIV 143
Query: 348 KQ 349
KQ
Sbjct: 144 KQ 145
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 67.0 bits (162), Expect = 2e-10
Identities = 53/165 (32%), Positives = 80/165 (48%), Gaps = 7/165 (4%)
Query: 204 HITKIVMEDCNLLEE-LKTQSCMDCIEEGELM--KMKGNEEFSKERFDIAIIYYTRAIEY 260
H T V++ C E+ LK Q + I + K KGNE F K + A+ +YT AI+
Sbjct: 330 HRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKR 389
Query: 261 RPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQ 320
P++ LY NRA C+ + +F+ AL D + L+ T+ KG+ R AL + +Y A+
Sbjct: 390 NPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMD 449
Query: 321 ANIKAQKL---CKNDPEGIKDLIQQHVKLQKQIEDLQGRTANKDP 362
KA L CK +G + + ED++ R A DP
Sbjct: 450 VYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVK-RRAMADP 493
Score = 65.1 bits (157), Expect = 7e-10
Identities = 44/172 (25%), Positives = 81/172 (47%), Gaps = 16/172 (9%)
Query: 228 IEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGD 287
+E+ +K KGN+ S D A+ Y+ AI+ P N++LY NR+ + + G ++ A D
Sbjct: 1 MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED 60
Query: 288 GKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQ 347
G + LK W KG+ R AL L ++ A + + K N+P+ L+
Sbjct: 61 GCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQ-----------LK 109
Query: 348 KQIEDLQGRTANKDPIKAF-----YENRAYTPRSLSAPIFTTSLNFVEKERD 394
+ +++++ R A + + F Y+ PR+ + T +E+ R+
Sbjct: 110 EGLQNMEARLAERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRN 161
Score = 34.3 bits (77), Expect = 1.3
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 216 LEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCF 275
+EE ++ ++E EL GN+ + K+ FD A+ +Y +A E P N N+A +
Sbjct: 214 MEEDLPENKKQALKEKEL----GNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVY 269
Query: 276 LRTGQF 281
G +
Sbjct: 270 FEKGDY 275
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 64.3 bits (155), Expect = 1e-09
Identities = 30/75 (40%), Positives = 48/75 (64%)
Query: 230 EGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGK 289
E E K +GN ++K+ ++ A YYT+AI+ P+N YGNRA + G+FR ALGD +
Sbjct: 27 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ 86
Query: 290 RATILKNTWPKGHYR 304
++ L +++ +GH R
Sbjct: 87 QSVRLDDSFVRGHLR 101
Score = 35.8 bits (81), Expect = 0.44
Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 11/161 (6%)
Query: 222 QSCMDCIEEGELMKMK--GNEEFSKERFDIAIIYYTRAIEYRPENY----LLYGNRALCF 275
++C+ C L K GN+ F + + +A YT A+ P N LY NR
Sbjct: 245 KACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVN 304
Query: 276 LRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQ--ANIKAQKLCKNDP 333
+ + +A+ D A L +T+ K + R +Y+ A++ + + K
Sbjct: 305 SKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHK 364
Query: 334 EGIKDL-IQQHVKLQKQIEDLQG--RTANKDPIKAFYENRA 371
+ +K+ ++ +K + G + A++D IK Y RA
Sbjct: 365 QLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRA 405
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 59.3 bits (142), Expect = 4e-08
Identities = 74/345 (21%), Positives = 142/345 (41%), Gaps = 75/345 (21%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQ----EVYENYEQIKLKGLEETRDLEEKLKRHLEENKISK 1542
E++ EIS I+K+ + + D+LQ E+YE EQ +K + E ++ +LK+ E K
Sbjct: 1502 EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKD 1561
Query: 1543 T----------ELDWFLQDLEREIK---KWQQEKKEIQERLKSLKKKIKKVSNASEMYTQ 1589
+ EL LQ+ + EI+ K ++E K +QE L+ + ++K+ N E+ +
Sbjct: 1562 SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKE--NTKEIVAK 1619
Query: 1590 KNDGKEKEHEL------------------------------------------HLDQSLE 1607
+ +EKE++ L ++LE
Sbjct: 1620 MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLE 1679
Query: 1608 ISNTLTNEK---MKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAE 1664
++T E+ +EE +K ++ +E+ + + + LE +E ++ + + E Q E
Sbjct: 1680 EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRD---LEKQEELKIVHMHLKEHQ-E 1735
Query: 1665 AFLKKLGLISRDPAAYPDMESDIRSWELFLS----NVTKEIEKAKSQFEEQIKAIK--NG 1718
K G++S +M+ D+ L + +E+ A +EQ + I G
Sbjct: 1736 TIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRG 1795
Query: 1719 SRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDV 1763
+ K+ + N E + E ++ Q L+T DV
Sbjct: 1796 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQ-LITLKKDV 1839
Score = 52.0 bits (123), Expect = 6e-06
Identities = 66/280 (23%), Positives = 128/280 (45%), Gaps = 47/280 (16%)
Query: 1483 NPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIK----------LKGLEETRDLEEKLK 1532
N E+Q +I + +E LQ L+ V EQ+K ++ EE R L ++LK
Sbjct: 1036 NEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELK 1095
Query: 1533 RHLE------------ENKISKT-----ELDWFLQDLEREIKKWQQEKKEIQERLKSLKK 1575
+ E E ++S+T E++ L++ +++++ QQ+ +QE + ++K
Sbjct: 1096 KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK 1155
Query: 1576 KIKKVSNASEMYTQKNDGKEKEHEL-HLD-QSLEISNTLTNEKMKIEEYIKKGKEDYEES 1633
KI ++ N KN+ K KE L H++ + LE++ L NE + + I K ++ +E
Sbjct: 1156 KINEIENL------KNELKNKELTLEHMETERLELAQKL-NENYEEVKSITKERKVLKEL 1208
Query: 1634 HQRAVAAEVSVLENW-KESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWEL 1692
Q++ E L + +E E LQ E A + + ++ +
Sbjct: 1209 -QKSFETERDHLRGYIREIEATGLQTKEELKIAHIH----LKEHQETIDELRRSVSEKTA 1263
Query: 1693 FLSNVTKEIEKAKSQFEEQIKAIKNGSRL----SELSKVQ 1728
+ N T+++EK+ ++ +E+I + L E+S+ Q
Sbjct: 1264 QIIN-TQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQ 1302
Score = 49.3 bits (116), Expect = 4e-05
Identities = 61/247 (24%), Positives = 109/247 (44%), Gaps = 30/247 (12%)
Query: 1474 HQEVNTEPYNPFEERQGEISR---IEKEHQVLQDQLQEVYENYEQI-KLKGLEETRDLEE 1529
HQE E E+ +I +EK H LQ+++ ++E E + +K + ET++
Sbjct: 1247 HQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMN 1306
Query: 1530 KLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQ 1589
+L+ E+ S T+ L +E E + ++ +E QE +KSL K+ + E
Sbjct: 1307 ELELLTEQ---STTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEV 1363
Query: 1590 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYE-ESHQRAVAAEVSVLENW 1648
K+D + KEH I TL KI+E K ++ + VS +E +
Sbjct: 1364 KHD-QLKEH---------IRETLA----KIQESQSKQEQSLNMKEKDNETTKIVSEMEQF 1409
Query: 1649 KESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQF 1708
K + L+I ++ LGL R ++ +M+S + + L + + ++ Q
Sbjct: 1410 KPKDSALLRIE-------IEMLGLSKRLQESHDEMKSVAKEKD-DLQRLQEVLQSESDQL 1461
Query: 1709 EEQIKAI 1715
+E IK I
Sbjct: 1462 KENIKEI 1468
Score = 48.9 bits (115), Expect = 5e-05
Identities = 42/190 (22%), Positives = 94/190 (49%), Gaps = 11/190 (5%)
Query: 1475 QEVNTEPYNPFEERQGEIS----RIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEK 1530
QE+ + N +++GE+S R+ + + L+++ Q++ E +Q+ L EE ++++K
Sbjct: 1098 QEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL-LNVQEEMSEMQKK 1156
Query: 1531 LKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQK 1590
+ +E K + L+ +E E + Q+ E E +KS+ K+ K + QK
Sbjct: 1157 I-NEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKE-----LQK 1210
Query: 1591 NDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKE 1650
+ E++H + +E + T E++KI K ++ + +R+V+ + + + N ++
Sbjct: 1211 SFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD 1270
Query: 1651 SEVYKLQIME 1660
E ++ E
Sbjct: 1271 LEKSHTKLQE 1280
Score = 44.3 bits (103), Expect = 0.001
Identities = 50/200 (25%), Positives = 92/200 (46%), Gaps = 29/200 (14%)
Query: 1487 ERQGEISRIEKEHQVLQDQ--------------LQEVYENYEQIK--LKGLEETRDLEEK 1530
E Q ++S +E+ + ++DQ Q+++EN E++K +K + R +EE
Sbjct: 1841 ETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEET 1900
Query: 1531 LKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQK 1590
LK ++ K S E ++++E+K + KE +E + L++KI SE Q
Sbjct: 1901 LKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKI------SEKTIQI 1954
Query: 1591 NDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKE 1650
+D ++ LD+S + E K E + + KED SH++ E+ L+ E
Sbjct: 1955 SDIQK-----DLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK--INEMEQLKKQFE 2007
Query: 1651 SEVYKLQIMESQAEAFLKKL 1670
++ +Q + KKL
Sbjct: 2008 AQNLSMQSVRMDNFQLTKKL 2027
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/276 (18%), Positives = 124/276 (44%), Gaps = 26/276 (9%)
Query: 1457 NIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQI 1516
N+ +++ I+++ I+H+ N E + + ++ +E+ +V +DQL+ EN +
Sbjct: 1659 NLENIETENIRLT-QILHE--NLEEMRSVTKERDDLRSVEETLKVERDQLK---ENLRET 1712
Query: 1517 KLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKK 1576
+ LE+ +L + + HL+E++ + +L + + EI Q++ + + LK+ K
Sbjct: 1713 ITRDLEKQEEL-KIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLK 1771
Query: 1577 IKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQR 1636
I++ + M+ KE + +D+ I + T++ +++ ++ +E Q
Sbjct: 1772 IQEELRIAHMHL-------KEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE 1824
Query: 1637 AVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSN 1696
A E ++ K + E+Q KK+ + + D + E+ N
Sbjct: 1825 LKANEHQLI-------TLKKDVNETQ-----KKVSEMEQLKKQIKDQSLTLSKLEIENLN 1872
Query: 1697 VTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISEL 1732
+ +++ + + + +K N R+ E K++ +L
Sbjct: 1873 LAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQL 1908
Score = 42.0 bits (97), Expect = 0.006
Identities = 70/293 (23%), Positives = 129/293 (44%), Gaps = 42/293 (14%)
Query: 1478 NTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLE- 1536
N E + + + R+E+ ++ +DQL+E + + L+ +E + K H E
Sbjct: 1880 NLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKET 1939
Query: 1537 ----ENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKND 1592
KIS+ + + D+++++ K K E+Q++++ L+KK ++ E N
Sbjct: 1940 VDKLREKISEKTIQ--ISDIQKDLDK---SKDELQKKIQELQKKELQLLRVKE---DVNM 1991
Query: 1593 GKEKEHEL-HLDQSLEISN-TLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKE 1650
+K +E+ L + E N ++ + +M + KK E EE R VA E L KE
Sbjct: 1992 SHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEI--RIVAKERDELRRIKE 2049
Query: 1651 SEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEE 1710
S L++ Q A L++ +I+RD + ++ + R ++T+ + + S+ +E
Sbjct: 2050 S----LKMERDQFIATLRE--MIARDRQNH-QVKPEKRLLSDGQQHLTESLREKCSRIKE 2102
Query: 1711 QIKAIKNG-------SRLS-----------ELSKVQISELSFPACNTVHPELL 1745
+K +RLS ELS + LS P T H E L
Sbjct: 2103 LLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKL 2155
Score = 38.9 bits (89), Expect = 0.052
Identities = 37/164 (22%), Positives = 79/164 (48%), Gaps = 10/164 (6%)
Query: 1462 QMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGL 1521
+M I N+ + + E YN ++ + E+S + + +DQ++++ E + KL+ +
Sbjct: 549 EMQLIHEISNLKNLVKHAEVYN--QDLENELSSKVELLREKEDQIKKLQEYIDSQKLENI 606
Query: 1522 EETRDLEEKLKRHLEENKISKTELD--WFLQDLEREIKKWQQEKKEIQERLKSLKKKIKK 1579
+ DL L+ + ++ +T D D +RE + E E++E++K L K+
Sbjct: 607 K--MDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQ 664
Query: 1580 VSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYI 1623
+ N ++Y + + K+K + +D E+ + NE K+ I
Sbjct: 665 MENDIQLYQSQLEAKKK---MQVDLEKELQSAF-NEITKLTSLI 704
Score = 38.9 bits (89), Expect = 0.052
Identities = 44/249 (17%), Positives = 119/249 (47%), Gaps = 16/249 (6%)
Query: 1478 NTEPYNPFEERQGEISRIEKEHQVLQDQLQ---EVYENYEQIKLKGLEETRDLEEKLKRH 1534
N E +E ++E + Q+ Q QL+ ++ + E+ E L +
Sbjct: 648 NLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGK 707
Query: 1535 LEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGK 1594
+ ++ + EL+ + DL++E+ K +E + ++E + L ++K S SE+ + + +
Sbjct: 708 VPKDLLCNLELEGKITDLQKELNKEVEENEALREEV-ILLSELK--SLPSEVERLRKEIQ 764
Query: 1595 EKEHELHL--DQSLEISNTLTNEKMKIE---EYIKKGKEDY--EESHQRAVAAEVSVLEN 1647
+K ELH+ + ++ + + +++ +++ E I K K+D +S+ ++ E +
Sbjct: 765 DKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKT 824
Query: 1648 WKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQ 1707
K +++ + E +++ +S++ + +S + + + LS T+E+++ +
Sbjct: 825 LHMDFEQKYKMVLEENERMNQEIVNLSKEAQKF---DSSLGALKTELSYKTQELQEKTRE 881
Query: 1708 FEEQIKAIK 1716
+E++ ++
Sbjct: 882 VQERLNEME 890
Score = 38.5 bits (88), Expect = 0.068
Identities = 54/250 (21%), Positives = 105/250 (42%), Gaps = 16/250 (6%)
Query: 1474 HQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKR 1533
++ +N E N +E Q S + L + QE+ E +++ + L E L+E+L+
Sbjct: 840 NERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQER-LNEMEQLKEQLEN 898
Query: 1534 H---LEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQK 1590
L+ + KT + LQ E+K QEK ++++ +SL +I++ S+++
Sbjct: 899 RDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESL--QIERDQLKSDIHDTV 956
Query: 1591 NDGKEKEHELH--LDQSLEISNTLTNEKMKIEEYIKKG-------KEDYEESHQRAVAAE 1641
N + + +L L+ + T+ K KI E + + E +E Q+ V +
Sbjct: 957 NMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGID 1016
Query: 1642 VSVLENWKESEVYKLQIMESQ-AEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKE 1700
K ++ + +++ E K LI +ES I E +++ +
Sbjct: 1017 KKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKEN 1076
Query: 1701 IEKAKSQFEE 1710
IE EE
Sbjct: 1077 IEMTIENQEE 1086
Score = 37.4 bits (85), Expect = 0.15
Identities = 70/317 (22%), Positives = 135/317 (42%), Gaps = 33/317 (10%)
Query: 1427 VLSESNRNDEHCGNSNNKCEV-----IPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEP 1481
VLS + E S NK E+ + + + I H+Q S + ++N
Sbjct: 2176 VLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNM 2235
Query: 1482 YNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEE---TRDLEEKLKRHLEEN 1538
EE + S E E ++ + Q+V N +++ + LEE TR EKLK +++
Sbjct: 2236 DLHIEEILKDFS--ESEFPSIKTEFQQVLSNRKEMT-QFLEEWLNTRFDIEKLKNGIQKE 2292
Query: 1539 KISKTELDWFLQD----LEREIKKWQQEK----KEIQERLKSLKKKIKKV-SNASEMYTQ 1589
+++ F + + E ++++ KE ++ LKSLK+K +K+ N + T
Sbjct: 2293 NDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTS 2352
Query: 1590 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWK 1649
G + +++ +++ T E I++ + E+ + A+ E +++ K
Sbjct: 2353 LASGAQVNPTTQDNKNPHVTSRAT---QLTTEKIRELENSLHEAKESAMHKESKIIKMQK 2409
Query: 1650 ESEV-----YKLQIMESQAEAFLKKLG---LISRDPAAY--PDMESDIRSWELFLSNVTK 1699
E EV KLQ ++ L+K + +D A + +I ++ L +
Sbjct: 2410 ELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDL 2469
Query: 1700 EIEKAKSQFEEQIKAIK 1716
E K +FE++I A K
Sbjct: 2470 EKMKNAKEFEKEISATK 2486
Score = 36.6 bits (83), Expect = 0.26
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 19/174 (10%)
Query: 1474 HQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLE----- 1528
H+E + E+ +IS I+K+ +D+LQ+ + ++ +L+ L D+
Sbjct: 1936 HKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK 1995
Query: 1529 ----EKLKRHLEENKIS--KTELDWF-----LQDLEREIKKWQQEKKEIQERLKSLK-KK 1576
E+LK+ E +S +D F L + EI+ +E+ E++ +SLK ++
Sbjct: 1996 INEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMER 2055
Query: 1577 IKKVSNASEMYT--QKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKE 1628
+ ++ EM ++N + E L D ++ +L + +I+E +K+ E
Sbjct: 2056 DQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSE 2109
Score = 35.8 bits (81), Expect = 0.44
Identities = 35/145 (24%), Positives = 64/145 (44%), Gaps = 19/145 (13%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL----- 1545
EI + + + Q + + ++ K + D E+K K LEEN+ E+
Sbjct: 797 EIGKTKDDLATTQSNYKSTDQEFQNFKTLHM----DFEQKYKMVLEENERMNQEIVNLSK 852
Query: 1546 -----DWFLQDLEREI----KKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEK 1596
D L L+ E+ ++ Q++ +E+QERL +++ +++ N K
Sbjct: 853 EAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTL 912
Query: 1597 EHELHLDQSLEISNTLTNEKMKIEE 1621
E L Q+LE TLT EK +++
Sbjct: 913 ITE-KLQQTLEEVKTLTQEKDDLKQ 936
Score = 33.5 bits (75), Expect = 2.2
Identities = 60/260 (23%), Positives = 112/260 (43%), Gaps = 52/260 (20%)
Query: 1497 KEHQVLQDQLQEVYENY---EQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLE 1553
K H++ + L+E+ E+ + L+ ++E L + ++EL+ D +
Sbjct: 449 KTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYD 508
Query: 1554 REIKKWQQ---EKKEIQERLK---------SLKKKIKK---------VSNA------SEM 1586
+ ++Q EK+E++ +LK +L++K KK +SN +E+
Sbjct: 509 NLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEV 568
Query: 1587 YTQKNDG---------KEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRA 1637
Y Q + +EKE ++ Q S L N KM + Y + ED ++ Q
Sbjct: 569 YNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDL-SYSLESIEDPKQMKQTL 627
Query: 1638 VAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNV 1697
AE L+ +ES + + +E + + +K+L Y ME+DI+ ++ L
Sbjct: 628 FDAETVALDAKRESAFLRSENLELKEK--MKELA------TTYKQMENDIQLYQSQLEAK 679
Query: 1698 TK---EIEK-AKSQFEEQIK 1713
K ++EK +S F E K
Sbjct: 680 KKMQVDLEKELQSAFNEITK 699
Score = 31.6 bits (70), Expect = 8.3
Identities = 57/273 (20%), Positives = 115/273 (42%), Gaps = 36/273 (13%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E+ E ++I E E ++ + L+ E L ++L+ +E K E
Sbjct: 1393 KEKDNETTKIVSE--------MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEK 1444
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSL-KKKIKKVSNASEMYTQKNDGKEKEHELHLDQ 1604
D DL+R + Q E +++E +K + K ++ + + +E +EL ++
Sbjct: 1445 D----DLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL 1500
Query: 1605 SLEISNTLTNEKM----------KIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVY 1654
S + + T +K KI+E +K +E + V +V+ L+ +KE
Sbjct: 1501 SEKETEISTIQKQLEAINDKLQNKIQEIYEK-EEQFNIKQISEVQEKVNELKQFKEHRKA 1559
Query: 1655 K---LQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQ 1711
K LQ +ES K L L +R + +++ I+ E + V + ++ + Q +E
Sbjct: 1560 KDSALQSIES------KMLELTNRLQESQEEIQIMIKEKE-EMKRVQEALQIERDQLKEN 1612
Query: 1712 IKAIKNGSRLSELSKVQISELSFPACNTVHPEL 1744
K I +++ E + + L A N ++
Sbjct: 1613 TKEIV--AKMKESQEKEYQFLKMTAVNETQEKM 1643
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 58.9 bits (141), Expect = 5e-08
Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 3/105 (2%)
Query: 230 EGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGK 289
E E +K +GNE+ E F+ A+ +Y +AIE P N + + NRA + + G + A+ D +
Sbjct: 90 EAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCE 149
Query: 290 RATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPE 334
RA + + K + R ALS L ++ A+ KA +L DP+
Sbjct: 150 RAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALEL---DPD 191
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/301 (20%), Positives = 135/301 (44%), Gaps = 23/301 (7%)
Query: 1435 DEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISR 1494
+EH G N+ +++ + A+ ++ + + + I ++ + Y +E Q I+
Sbjct: 278 NEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYE-LQKRIAE 336
Query: 1495 IEKEHQVLQDQLQEVYE------NYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWF 1548
+E + + + + +E+ E N + K K +++T K+ + +EENK T+LD
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396
Query: 1549 LQDLEREIKKWQQEKKEIQERLKSLKKKIK-------KVSNASEMYTQKNDGKEKEHELH 1601
+ ++K + K+++++L+ K+K++ K +N T +N+ EKE E
Sbjct: 397 DVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKE 456
Query: 1602 LDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLE-NWKESEVY------ 1654
+ E+ ++L E +++ K+ +E ++V S ++ E ++Y
Sbjct: 457 EKKLKEVMDSLKQETQGLQKE-KESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNT 515
Query: 1655 KLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKA 1714
+ + EA + + AA D+E + E L KE++K +Q E K+
Sbjct: 516 AVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKL-TQEETNFKS 574
Query: 1715 I 1715
+
Sbjct: 575 L 575
Score = 35.4 bits (80), Expect = 0.57
Identities = 32/150 (21%), Positives = 69/150 (46%), Gaps = 12/150 (8%)
Query: 1483 NPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEK----LKRHLEEN 1538
N E + +EKE + + +L+EV ++ +Q + +GL++ ++ EK + + E
Sbjct: 437 NIINETTTRNNALEKEKEKEEKKLKEVMDSLKQ-ETQGLQKEKESREKELMGFSKSVNEA 495
Query: 1539 K----ISKTELDWFLQDLEREIKKWQQEKKEI---QERLKSLKKKIKKVSNASEMYTQKN 1591
+ ++++ELD +L + + + K+ + E LK K I+ + Q+
Sbjct: 496 RSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQEL 555
Query: 1592 DGKEKEHELHLDQSLEISNTLTNEKMKIEE 1621
KEKE + + + + + K+EE
Sbjct: 556 KEKEKELQKLTQEETNFKSLVHDLFQKVEE 585
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/301 (20%), Positives = 135/301 (44%), Gaps = 23/301 (7%)
Query: 1435 DEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISR 1494
+EH G N+ +++ + A+ ++ + + + I ++ + Y +E Q I+
Sbjct: 278 NEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYE-LQKRIAE 336
Query: 1495 IEKEHQVLQDQLQEVYE------NYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWF 1548
+E + + + + +E+ E N + K K +++T K+ + +EENK T+LD
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396
Query: 1549 LQDLEREIKKWQQEKKEIQERLKSLKKKIK-------KVSNASEMYTQKNDGKEKEHELH 1601
+ ++K + K+++++L+ K+K++ K +N T +N+ EKE E
Sbjct: 397 DVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKE 456
Query: 1602 LDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLE-NWKESEVY------ 1654
+ E+ ++L E +++ K+ +E ++V S ++ E ++Y
Sbjct: 457 EKKLKEVMDSLKQETQGLQKE-KESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNT 515
Query: 1655 KLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKA 1714
+ + EA + + AA D+E + E L KE++K +Q E K+
Sbjct: 516 AVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKL-TQEETNFKS 574
Query: 1715 I 1715
+
Sbjct: 575 L 575
Score = 35.4 bits (80), Expect = 0.57
Identities = 32/150 (21%), Positives = 69/150 (46%), Gaps = 12/150 (8%)
Query: 1483 NPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEK----LKRHLEEN 1538
N E + +EKE + + +L+EV ++ +Q + +GL++ ++ EK + + E
Sbjct: 437 NIINETTTRNNALEKEKEKEEKKLKEVMDSLKQ-ETQGLQKEKESREKELMGFSKSVNEA 495
Query: 1539 K----ISKTELDWFLQDLEREIKKWQQEKKEI---QERLKSLKKKIKKVSNASEMYTQKN 1591
+ ++++ELD +L + + + K+ + E LK K I+ + Q+
Sbjct: 496 RSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQEL 555
Query: 1592 DGKEKEHELHLDQSLEISNTLTNEKMKIEE 1621
KEKE + + + + + K+EE
Sbjct: 556 KEKEKELQKLTQEETNFKSLVHDLFQKVEE 585
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 58.5 bits (140), Expect = 6e-08
Identities = 61/281 (21%), Positives = 134/281 (47%), Gaps = 30/281 (10%)
Query: 1473 IHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQL-----------QEVYENYEQIKLK-- 1519
+ QE NTE + ++ Q ++EK + L +Q QE+ + +Q+K+
Sbjct: 2040 LEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR 2099
Query: 1520 ----GLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKK 1575
+TR++E+ L HL+E +EL + L+R+I++ +E ++++ R++ L++
Sbjct: 2100 FQPISEHQTREVEQ-LANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQ 2158
Query: 1576 K-IKKVSNASEMYTQKNDGK-EKEHELHLDQSLEISNTLTNEKMK----IEEYIKKGKED 1629
+ ++ +K+ G E + EL L+ L+ + K K +EE +++ +E+
Sbjct: 2159 ALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREE 2218
Query: 1630 YEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAF---LKKLGLISRDPAAYPDMESD 1686
E ++ + LE K+ +LQ +E + + F ++KLGL ++ A +
Sbjct: 2219 LENKNEEVQQLHMQ-LEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQH 2277
Query: 1687 IRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKV 1727
+ + + + +E E Q EQ+ ++ +++ +KV
Sbjct: 2278 VLFGK--FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKV 2316
Score = 43.9 bits (102), Expect = 0.002
Identities = 58/251 (23%), Positives = 101/251 (40%), Gaps = 22/251 (8%)
Query: 1496 EKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLERE 1555
EKE L+ ++QE+ E ++ + E+ DL+EK + EN I K E L+
Sbjct: 735 EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIH 794
Query: 1556 IKKWQQEKKEIQERLKSLKKK----------IKKVSNASEMYTQKNDGKEKEHELHLDQS 1605
Q+E+ + +KS K I++ + + Q N+ EK+ S
Sbjct: 795 TPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF---S 851
Query: 1606 LEISNTLTNEKMKIEEY--IKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQA 1663
N N + EEY + K K+D E+S + S L+ E +L +
Sbjct: 852 FAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNE----ELHLQRINP 907
Query: 1664 EAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSE 1723
K + D + + E+ + T+ +EK + E+++ + S LSE
Sbjct: 908 TTVKMKSSVFDEDKTF---VAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSE 964
Query: 1724 LSKVQISELSF 1734
K + E+SF
Sbjct: 965 QLKQKHGEISF 975
Score = 43.5 bits (101), Expect = 0.002
Identities = 57/249 (22%), Positives = 106/249 (42%), Gaps = 28/249 (11%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E Q + +EK+ + ++ LQE + E +E + LE+ LK H +S+ E
Sbjct: 746 QELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIH---TPVSQEER 802
Query: 1546 DWFLQDL---------EREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEK 1596
FL + E+EI+ +E ++++++ L ++I+K N + + +
Sbjct: 803 LIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQ 862
Query: 1597 EHELHLDQSLEISNTLTNEKMKIE-EYIKKGKEDYEESHQR-----AVAAEVSVLENWKE 1650
E + L++ + L + K K E EY K K EE H + V + SV + K
Sbjct: 863 ELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKT 922
Query: 1651 SEVYKL---QIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQ 1707
L +++E ++KL + R+ SD LS K+ S
Sbjct: 923 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSD-------LSEQLKQKHGEISF 975
Query: 1708 FEEQIKAIK 1716
E++K++K
Sbjct: 976 LNEEVKSLK 984
Score = 42.0 bits (97), Expect = 0.006
Identities = 66/274 (24%), Positives = 121/274 (44%), Gaps = 53/274 (19%)
Query: 1501 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRH----LEENKISKTELDWFLQDLEREI 1556
V +DQ++ + ++ +K L++T +EKLK LEE + +L+ +++L
Sbjct: 483 VNEDQIKLMNVAINELNIK-LQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 541
Query: 1557 KKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEK 1616
++ Q+ ++ I E+ L + K +S ++ + E EL L E+ TN K
Sbjct: 542 EQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEV----TNYK 597
Query: 1617 MKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQA----EAFLKKLGL 1672
+K+ E ++K K +VL+ ES+ +L+ + +Q E L KL
Sbjct: 598 IKL-EMLEKEKN--------------AVLDRMAESQEAELERLRTQLLFSHEEELSKL-- 640
Query: 1673 ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISEL 1732
D+E + R N+ K + +++QI ++N E+S+ +I +
Sbjct: 641 -------KEDLEIEHR------INIEKLKDNLGIHYKQQIDGLQN-----EMSQ-KIETM 681
Query: 1733 SFPACN--TVHPELLPESS--GDDGQGLVTSASD 1762
F N T +L+ E S D Q LV S S+
Sbjct: 682 QFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Score = 40.0 bits (92), Expect = 0.023
Identities = 40/179 (22%), Positives = 86/179 (48%), Gaps = 24/179 (13%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
E+ + ++ R E+ + ++L+++ + E K + L+ LE++ K+ L E++ K E
Sbjct: 3225 EKEKAKLGRSEERDK---EELEDLKFSLESQKQRNLQLNLLLEQQ-KQLLNESQ-QKIES 3279
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQS 1605
L D + + + Q E+Q L+S K +I+++S+ + +E ELH
Sbjct: 3280 QRMLYDAQ--LSEEQGRNLELQVLLESEKVRIREMSSTLD----------RERELHAQLQ 3327
Query: 1606 LEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAE 1664
+ + E+ +K+ ++ EE H R ++E E+E YKL ++++ +
Sbjct: 3328 SSDGTGQSRPPLPSEDLLKELQKQLEEKHSR-------IVELLNETEKYKLDSLQTRQQ 3379
Score = 38.1 bits (87), Expect = 0.088
Identities = 40/166 (24%), Positives = 77/166 (46%), Gaps = 18/166 (10%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E+ I R+E+E ++LQE+ +QI +E R+L + K + K E
Sbjct: 1939 QEKTDIIDRLEQELLCASNRLQELEAEQQQI-----QEERELLSRQKEAM------KAEA 1987
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGK----EKEHELH 1601
Q L +E +K +EK E+Q + + ++ ++K A E+ ++ + E+E
Sbjct: 1988 GPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTE 2047
Query: 1602 LDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAV-AAEVSVLE 1646
L + + L + K+ +++ + D E H+R V E+ LE
Sbjct: 2048 LMDLRQQNQALEKQLEKMRKFLDEQAIDRE--HERDVFQQEIQKLE 2091
Score = 37.7 bits (86), Expect = 0.12
Identities = 55/249 (22%), Positives = 107/249 (42%), Gaps = 31/249 (12%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEE---TRDLEEKLKR------HLEENKIS 1541
E+ + +K ++++QE E++ K +EE T +L++KL L+E +
Sbjct: 309 EMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 368
Query: 1542 KT-ELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHEL 1600
K E+ +L +K +Q +EI++ + ++++ K+ S+ T E+E +
Sbjct: 369 KNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQR 428
Query: 1601 HLDQ-SLEISNTLTNEKMKI-EEYIKKGKEDYEESHQRAVAAEVSVLENWKESEV----- 1653
L+Q E+ + +++ +E I++ EE R + L ++ V
Sbjct: 429 KLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI 488
Query: 1654 -----------YKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIE 1702
KLQ SQ E ++LGLI + A D+ EL S ++I+
Sbjct: 489 KLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVE-ELSFSR--EQIQ 545
Query: 1703 KAKSQFEEQ 1711
+A+ EQ
Sbjct: 546 RARQTIAEQ 554
Score = 35.8 bits (81), Expect = 0.44
Identities = 57/333 (17%), Positives = 132/333 (39%), Gaps = 27/333 (8%)
Query: 1389 HLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVI 1448
++N+ + E+ I+ + SH G + + SE + + C + N C +
Sbjct: 66 YINSSQRVESTVIPESTIMRTLHSGEITSH-EQGFSVELESEISTTADDCSSEVNGCSFV 124
Query: 1449 PESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQE 1508
T TN+ + + S++ Q P + E + E++ + E + L +L+E
Sbjct: 125 MR-TGKPTNLLREEEFGVDDSYS--EQGAQDSPTH-LEMMESELAGKQHEIEELNRELEE 180
Query: 1509 VYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQE 1568
+ Y +GL++ ++ E +K+ D + L +++ ++EK E
Sbjct: 181 MRVTYGT---EGLQQLQEFEAAIKQR-----------DGIITQLTANLQQARREKDETMR 226
Query: 1569 RLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKE 1628
L ++ +K+ + + H L+ + + ++EE E
Sbjct: 227 EFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQ-DHLLE 285
Query: 1629 DYEESHQRAVAAEVSVLENWKESEVYKLQ----IMESQAEAFLKKLGLISRDPAAYPDME 1684
DY++ + ++S L+ ++ +VY+++ + S E +K +I + E
Sbjct: 286 DYQKK-KEDFTMQISFLQ--EKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEE 342
Query: 1685 SDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKN 1717
+ L+ K + + + Q ++ + IKN
Sbjct: 343 KKTLELKDKLTTADKLLGELQEQIVQKNQEIKN 375
Score = 35.4 bits (80), Expect = 0.57
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 27/263 (10%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E++ EI ++ ++ LQ QL+ +N + I+ K E RDLE +++ + + + K
Sbjct: 2288 QEKEVEIDQLNEQVTKLQQQLKITTDN-KVIEEKN-ELIRDLETQIECLMSDQECVKRNR 2345
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLK----SLKKKIKKVSNASEMYTQKNDGKEKEHELH 1601
+ ++ L I+K QQE I ++ SL ++ + + ++ + E++ E
Sbjct: 2346 EEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETA 2405
Query: 1602 LDQSLEISNTLTNEKMKIEEY------IKKGKEDYEESH---QRAVAAEVSVLENWK-ES 1651
++ + N L K+ + +K+ +E E+ + +V + L K E
Sbjct: 2406 NEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPEL 2465
Query: 1652 EVY----KLQIMESQA--EAFLKK-LGLISRDPAAYPDMESDIRSWELFLSNVTKEIE-- 1702
EV L+ +E+Q ++F + G I +ES + + +L L+ K+I+
Sbjct: 2466 EVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDM 2525
Query: 1703 KAKSQFEEQI--KAIKNGSRLSE 1723
+ + QFE ++ K I N ++ E
Sbjct: 2526 QEQGQFETEMLQKKIVNLQKIVE 2548
Score = 35.0 bits (79), Expect = 0.75
Identities = 51/255 (20%), Positives = 108/255 (42%), Gaps = 27/255 (10%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLK---RHLEENKISKT 1543
E Q E+S ++ LQ+QL ++K + + +LE LK +HL+E
Sbjct: 3135 EMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKE------ 3188
Query: 1544 ELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQK---NDGKEKEHEL 1600
L+ E+K E + + L S +KK +++ A E K ++ ++KE
Sbjct: 3189 -----LEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELE 3243
Query: 1601 HLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQ--- 1657
L SLE + +++ +++ K+ ES Q+ + + E + L+
Sbjct: 3244 DLKFSLE---SQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV 3300
Query: 1658 IMESQAEAFLKKLGLISRDPAAYPDMESDIRSWE----LFLSNVTKEIEKAKSQFEEQIK 1713
++ES+ + + R+ + ++S + + L ++ KE++K + +I
Sbjct: 3301 LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIV 3360
Query: 1714 AIKNGSRLSELSKVQ 1728
+ N + +L +Q
Sbjct: 3361 ELLNETEKYKLDSLQ 3375
Score = 33.9 bits (76), Expect = 1.7
Identities = 29/108 (26%), Positives = 60/108 (55%), Gaps = 16/108 (14%)
Query: 1517 KLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKK 1576
KLK L+++ + + L+ N++ K E++ Q+ E+E +QE +E+Q + + L+K+
Sbjct: 701 KLKDLQQSLVNSKSEEMTLQINELQK-EIEILRQE-EKEKGTLEQEVQELQLKTELLEKQ 758
Query: 1577 IKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIK 1624
+K+ ++ND +EK +L + S+ L +EK +E+ +K
Sbjct: 759 MKE---------KENDLQEKFAQLEAENSI-----LKDEKKTLEDMLK 792
Score = 32.0 bits (71), Expect = 6.3
Identities = 64/316 (20%), Positives = 126/316 (39%), Gaps = 59/316 (18%)
Query: 1473 IHQEVNTEPYNP---------FEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEE 1523
+++E++ + NP F+E + ++ + +V++ E+ E E K + LE
Sbjct: 896 LNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLEL 955
Query: 1524 TR---DLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLK-----K 1575
++ DL E+LK+ E + L E+K +QEK+++ R + L+
Sbjct: 956 SQRLSDLSEQLKQKHGE-----------ISFLNEEVKSLKQEKEQVSLRCRELEIIINHN 1004
Query: 1576 KIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDY---EE 1632
+ + V + + DG + S+ N E+ KI K E+ EE
Sbjct: 1005 RAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEE 1064
Query: 1633 SHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWEL 1692
S Q + + + KES + Q S+ + K+L ++ + D+ + + +
Sbjct: 1065 SKQEQLILD-HLPSVTKESSLRATQ--PSENDKLQKELNVLKSE---QNDLRLQMEAQRI 1118
Query: 1693 FLSNV------------TKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV 1740
LS V E +KA +E++ ++ EL K+ EL
Sbjct: 1119 CLSLVYSTHVDQVREYMENEKDKALCSLKEEL-IFAQEEKIKELQKIHQLELQ------- 1170
Query: 1741 HPELLPESSGDDGQGL 1756
+ + +GD+G+ L
Sbjct: 1171 --TMKTQETGDEGKPL 1184
Score = 32.0 bits (71), Expect = 6.3
Identities = 23/79 (29%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 1494 RIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLE 1553
++EK+ QV + LQ E + + K + E + E L+R LEE + +LD Q L+
Sbjct: 3379 QMEKDRQVHRKTLQTEQEANTEGQKK-MHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQ 3437
Query: 1554 REIKKWQQEKKEIQERLKS 1572
++++Q+++ E +E+ +S
Sbjct: 3438 GIMQEFQKQELEREEKRES 3456
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 57.8 bits (138), Expect = 1e-07
Identities = 28/75 (37%), Positives = 42/75 (56%)
Query: 247 FDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYC 306
F AI+ Y A+ P+N +LY NR+ +++ Q+ AL D +A +L WPK ++R
Sbjct: 74 FHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQG 133
Query: 307 DALSMLGEYDWALQA 321
AL LG + AL A
Sbjct: 134 VALQYLGRHADALAA 148
>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 2 [Homo sapiens]
Length = 602
Score = 57.8 bits (138), Expect = 1e-07
Identities = 55/265 (20%), Positives = 125/265 (47%), Gaps = 34/265 (12%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+ R EIS+++ + L+ Q ++V E+ K K + + + L+ L+ I K EL
Sbjct: 86 DSRSVEISQLKNTIKSLKQQKKQVEHQLEEEK-KANNKKQKAKRVLEVQLQTLNIQKEEL 144
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLK------------------SLKKKIKKVSNASEMY 1587
+ L ++R ++ ++++ K++ RL+ + KKK ++S+ S+
Sbjct: 145 NTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQLSSPSKAG 204
Query: 1588 TQ-KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIK--KGKEDYEESHQRAVAAEVSV 1644
T+ K + +E L Q ++ + +++ +EY + KG+ + R ++ E+
Sbjct: 205 TEWKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICT 264
Query: 1645 LENWKESEVYKLQIMESQAEAFLKKLGL-ISRDPAAYPDMESDIRSWELFLSNVTKEIEK 1703
L+ K+ ++ +++ +E ++ + +P A P E+ L ++ KE+E+
Sbjct: 265 LKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPS--------EVELQHLRKELER 316
Query: 1704 AKSQFEEQIKAIKNGSRLSELSKVQ 1728
+ + Q +KN R+S L++ Q
Sbjct: 317 VAGELQAQ---VKNNQRISLLNQRQ 338
Score = 35.4 bits (80), Expect = 0.57
Identities = 63/262 (24%), Positives = 108/262 (41%), Gaps = 62/262 (23%)
Query: 1471 NIIHQEVNTEPYNP------FEER--------QGEISRIEKEHQVLQDQLQEVYENYEQI 1516
NI +E+NT+ Y+ FEE+ Q + R + VL D + + Q+
Sbjct: 138 NIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQL 197
Query: 1517 KLKG-------LEETRDLEEKLKRHLEENKIS----KTELDWFLQDLEREIKKWQQEKKE 1565
LE++ E LK L + K S + E D + + L+ E +WQQ ++
Sbjct: 198 SSPSKAGTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRK 257
Query: 1566 IQERLKSLKKK--------------IKKVSN-ASEMYTQKNDGKEKEHEL-HLDQSLE-- 1607
+ + + +LKK+ + K+ N +E + E EL HL + LE
Sbjct: 258 MSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERV 317
Query: 1608 -------ISN----TLTNEKM-----KIEEYIKKGKEDYEESHQ--RAVAAEVSVLENWK 1649
+ N +L N++ + EE ++K +E +E H+ + +A SV E
Sbjct: 318 AGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPN 377
Query: 1650 ESEVYKLQIMESQAEAFLKKLG 1671
LQ +E Q + +KLG
Sbjct: 378 NENKSTLQ-LEQQVKELQEKLG 398
>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 57.8 bits (138), Expect = 1e-07
Identities = 55/265 (20%), Positives = 125/265 (47%), Gaps = 34/265 (12%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+ R EIS+++ + L+ Q ++V E+ K K + + + L+ L+ I K EL
Sbjct: 87 DSRSVEISQLKNTIKSLKQQKKQVEHQLEEEK-KANNKKQKAKRVLEVQLQTLNIQKEEL 145
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLK------------------SLKKKIKKVSNASEMY 1587
+ L ++R ++ ++++ K++ RL+ + KKK ++S+ S+
Sbjct: 146 NTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQLSSPSKAG 205
Query: 1588 TQ-KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIK--KGKEDYEESHQRAVAAEVSV 1644
T+ K + +E L Q ++ + +++ +EY + KG+ + R ++ E+
Sbjct: 206 TEWKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICT 265
Query: 1645 LENWKESEVYKLQIMESQAEAFLKKLGL-ISRDPAAYPDMESDIRSWELFLSNVTKEIEK 1703
L+ K+ ++ +++ +E ++ + +P A P E+ L ++ KE+E+
Sbjct: 266 LKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPS--------EVELQHLRKELER 317
Query: 1704 AKSQFEEQIKAIKNGSRLSELSKVQ 1728
+ + Q +KN R+S L++ Q
Sbjct: 318 VAGELQAQ---VKNNQRISLLNQRQ 339
Score = 35.4 bits (80), Expect = 0.57
Identities = 63/262 (24%), Positives = 108/262 (41%), Gaps = 62/262 (23%)
Query: 1471 NIIHQEVNTEPYNP------FEER--------QGEISRIEKEHQVLQDQLQEVYENYEQI 1516
NI +E+NT+ Y+ FEE+ Q + R + VL D + + Q+
Sbjct: 139 NIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQL 198
Query: 1517 KLKG-------LEETRDLEEKLKRHLEENKIS----KTELDWFLQDLEREIKKWQQEKKE 1565
LE++ E LK L + K S + E D + + L+ E +WQQ ++
Sbjct: 199 SSPSKAGTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRK 258
Query: 1566 IQERLKSLKKK--------------IKKVSN-ASEMYTQKNDGKEKEHEL-HLDQSLE-- 1607
+ + + +LKK+ + K+ N +E + E EL HL + LE
Sbjct: 259 MSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERV 318
Query: 1608 -------ISN----TLTNEKM-----KIEEYIKKGKEDYEESHQ--RAVAAEVSVLENWK 1649
+ N +L N++ + EE ++K +E +E H+ + +A SV E
Sbjct: 319 AGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPN 378
Query: 1650 ESEVYKLQIMESQAEAFLKKLG 1671
LQ +E Q + +KLG
Sbjct: 379 NENKSTLQ-LEQQVKELQEKLG 399
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 57.4 bits (137), Expect = 1e-07
Identities = 62/280 (22%), Positives = 131/280 (46%), Gaps = 36/280 (12%)
Query: 1473 IHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQL-----------QEVYENYEQIKLK-- 1519
+ QE NTE + ++ Q ++EK + L +Q QE+ + +Q+K+
Sbjct: 2040 LEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR 2099
Query: 1520 ----GLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKK 1575
+TR++E+ L HL+E +EL + L+R+I +E E ++ L+
Sbjct: 2100 FQPISEHQTREVEQ-LANHLKEKTDKCSELLLSKEQLQRDI-------QERNEEIEKLEF 2151
Query: 1576 KIKKVSNASEMYTQKNDGK-EKEHELHLDQSLEISNTLTNEKMK----IEEYIKKGKEDY 1630
+++++ A + +K+ G E + EL L+ L+ + K K +EE +++ +E+
Sbjct: 2152 RVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREEL 2211
Query: 1631 EESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAF---LKKLGLISRDPAAYPDMESDI 1687
E ++ + LE K+ +LQ +E + + F ++KLGL ++ A + +
Sbjct: 2212 ENKNEEVQQLHMQ-LEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHV 2270
Query: 1688 RSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKV 1727
+ + + +E E Q EQ+ ++ +++ +KV
Sbjct: 2271 LFGK--FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKV 2308
Score = 43.9 bits (102), Expect = 0.002
Identities = 58/251 (23%), Positives = 101/251 (40%), Gaps = 22/251 (8%)
Query: 1496 EKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLERE 1555
EKE L+ ++QE+ E ++ + E+ DL+EK + EN I K E L+
Sbjct: 735 EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIH 794
Query: 1556 IKKWQQEKKEIQERLKSLKKK----------IKKVSNASEMYTQKNDGKEKEHELHLDQS 1605
Q+E+ + +KS K I++ + + Q N+ EK+ S
Sbjct: 795 TPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF---S 851
Query: 1606 LEISNTLTNEKMKIEEY--IKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQA 1663
N N + EEY + K K+D E+S + S L+ E +L +
Sbjct: 852 FAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNE----ELHLQRINP 907
Query: 1664 EAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSE 1723
K + D + + E+ + T+ +EK + E+++ + S LSE
Sbjct: 908 TTVKMKSSVFDEDKTF---VAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSE 964
Query: 1724 LSKVQISELSF 1734
K + E+SF
Sbjct: 965 QLKQKHGEISF 975
Score = 43.5 bits (101), Expect = 0.002
Identities = 57/249 (22%), Positives = 106/249 (42%), Gaps = 28/249 (11%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E Q + +EK+ + ++ LQE + E +E + LE+ LK H +S+ E
Sbjct: 746 QELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIH---TPVSQEER 802
Query: 1546 DWFLQDL---------EREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEK 1596
FL + E+EI+ +E ++++++ L ++I+K N + + +
Sbjct: 803 LIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQ 862
Query: 1597 EHELHLDQSLEISNTLTNEKMKIE-EYIKKGKEDYEESHQR-----AVAAEVSVLENWKE 1650
E + L++ + L + K K E EY K K EE H + V + SV + K
Sbjct: 863 ELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKT 922
Query: 1651 SEVYKL---QIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQ 1707
L +++E ++KL + R+ SD LS K+ S
Sbjct: 923 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSD-------LSEQLKQKHGEISF 975
Query: 1708 FEEQIKAIK 1716
E++K++K
Sbjct: 976 LNEEVKSLK 984
Score = 42.0 bits (97), Expect = 0.006
Identities = 66/274 (24%), Positives = 121/274 (44%), Gaps = 53/274 (19%)
Query: 1501 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRH----LEENKISKTELDWFLQDLEREI 1556
V +DQ++ + ++ +K L++T +EKLK LEE + +L+ +++L
Sbjct: 483 VNEDQIKLMNVAINELNIK-LQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 541
Query: 1557 KKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEK 1616
++ Q+ ++ I E+ L + K +S ++ + E EL L E+ TN K
Sbjct: 542 EQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEV----TNYK 597
Query: 1617 MKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQA----EAFLKKLGL 1672
+K+ E ++K K +VL+ ES+ +L+ + +Q E L KL
Sbjct: 598 IKL-EMLEKEKN--------------AVLDRMAESQEAELERLRTQLLFSHEEELSKL-- 640
Query: 1673 ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISEL 1732
D+E + R N+ K + +++QI ++N E+S+ +I +
Sbjct: 641 -------KEDLEIEHR------INIEKLKDNLGIHYKQQIDGLQN-----EMSQ-KIETM 681
Query: 1733 SFPACN--TVHPELLPESS--GDDGQGLVTSASD 1762
F N T +L+ E S D Q LV S S+
Sbjct: 682 QFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Score = 40.0 bits (92), Expect = 0.023
Identities = 40/179 (22%), Positives = 86/179 (48%), Gaps = 24/179 (13%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
E+ + ++ R E+ + ++L+++ + E K + L+ LE++ K+ L E++ K E
Sbjct: 3217 EKEKAKLGRSEERDK---EELEDLKFSLESQKQRNLQLNLLLEQQ-KQLLNESQ-QKIES 3271
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQS 1605
L D + + + Q E+Q L+S K +I+++S+ + +E ELH
Sbjct: 3272 QRMLYDAQ--LSEEQGRNLELQVLLESEKVRIREMSSTLD----------RERELHAQLQ 3319
Query: 1606 LEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAE 1664
+ + E+ +K+ ++ EE H R ++E E+E YKL ++++ +
Sbjct: 3320 SSDGTGQSRPPLPSEDLLKELQKQLEEKHSR-------IVELLNETEKYKLDSLQTRQQ 3371
Score = 38.1 bits (87), Expect = 0.088
Identities = 40/166 (24%), Positives = 77/166 (46%), Gaps = 18/166 (10%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E+ I R+E+E ++LQE+ +QI +E R+L + K + K E
Sbjct: 1939 QEKTDIIDRLEQELLCASNRLQELEAEQQQI-----QEERELLSRQKEAM------KAEA 1987
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGK----EKEHELH 1601
Q L +E +K +EK E+Q + + ++ ++K A E+ ++ + E+E
Sbjct: 1988 GPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTE 2047
Query: 1602 LDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAV-AAEVSVLE 1646
L + + L + K+ +++ + D E H+R V E+ LE
Sbjct: 2048 LMDLRQQNQALEKQLEKMRKFLDEQAIDRE--HERDVFQQEIQKLE 2091
Score = 37.7 bits (86), Expect = 0.12
Identities = 55/249 (22%), Positives = 107/249 (42%), Gaps = 31/249 (12%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEE---TRDLEEKLKR------HLEENKIS 1541
E+ + +K ++++QE E++ K +EE T +L++KL L+E +
Sbjct: 309 EMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 368
Query: 1542 KT-ELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHEL 1600
K E+ +L +K +Q +EI++ + ++++ K+ S+ T E+E +
Sbjct: 369 KNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQR 428
Query: 1601 HLDQ-SLEISNTLTNEKMKI-EEYIKKGKEDYEESHQRAVAAEVSVLENWKESEV----- 1653
L+Q E+ + +++ +E I++ EE R + L ++ V
Sbjct: 429 KLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI 488
Query: 1654 -----------YKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIE 1702
KLQ SQ E ++LGLI + A D+ EL S ++I+
Sbjct: 489 KLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVE-ELSFSR--EQIQ 545
Query: 1703 KAKSQFEEQ 1711
+A+ EQ
Sbjct: 546 RARQTIAEQ 554
Score = 35.8 bits (81), Expect = 0.44
Identities = 57/333 (17%), Positives = 132/333 (39%), Gaps = 27/333 (8%)
Query: 1389 HLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVI 1448
++N+ + E+ I+ + SH G + + SE + + C + N C +
Sbjct: 66 YINSSQRVESTVIPESTIMRTLHSGEITSH-EQGFSVELESEISTTADDCSSEVNGCSFV 124
Query: 1449 PESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQE 1508
T TN+ + + S++ Q P + E + E++ + E + L +L+E
Sbjct: 125 MR-TGKPTNLLREEEFGVDDSYS--EQGAQDSPTH-LEMMESELAGKQHEIEELNRELEE 180
Query: 1509 VYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQE 1568
+ Y +GL++ ++ E +K+ D + L +++ ++EK E
Sbjct: 181 MRVTYGT---EGLQQLQEFEAAIKQR-----------DGIITQLTANLQQARREKDETMR 226
Query: 1569 RLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKE 1628
L ++ +K+ + + H L+ + + ++EE E
Sbjct: 227 EFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQ-DHLLE 285
Query: 1629 DYEESHQRAVAAEVSVLENWKESEVYKLQ----IMESQAEAFLKKLGLISRDPAAYPDME 1684
DY++ + ++S L+ ++ +VY+++ + S E +K +I + E
Sbjct: 286 DYQKK-KEDFTMQISFLQ--EKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEE 342
Query: 1685 SDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKN 1717
+ L+ K + + + Q ++ + IKN
Sbjct: 343 KKTLELKDKLTTADKLLGELQEQIVQKNQEIKN 375
Score = 35.4 bits (80), Expect = 0.57
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 27/263 (10%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E++ EI ++ ++ LQ QL+ +N + I+ K E RDLE +++ + + + K
Sbjct: 2280 QEKEVEIDQLNEQVTKLQQQLKITTDN-KVIEEKN-ELIRDLETQIECLMSDQECVKRNR 2337
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLK----SLKKKIKKVSNASEMYTQKNDGKEKEHELH 1601
+ ++ L I+K QQE I ++ SL ++ + + ++ + E++ E
Sbjct: 2338 EEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETA 2397
Query: 1602 LDQSLEISNTLTNEKMKIEEY------IKKGKEDYEESH---QRAVAAEVSVLENWK-ES 1651
++ + N L K+ + +K+ +E E+ + +V + L K E
Sbjct: 2398 NEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPEL 2457
Query: 1652 EVY----KLQIMESQA--EAFLKK-LGLISRDPAAYPDMESDIRSWELFLSNVTKEIE-- 1702
EV L+ +E+Q ++F + G I +ES + + +L L+ K+I+
Sbjct: 2458 EVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDM 2517
Query: 1703 KAKSQFEEQI--KAIKNGSRLSE 1723
+ + QFE ++ K I N ++ E
Sbjct: 2518 QEQGQFETEMLQKKIVNLQKIVE 2540
Score = 35.0 bits (79), Expect = 0.75
Identities = 51/255 (20%), Positives = 108/255 (42%), Gaps = 27/255 (10%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLK---RHLEENKISKT 1543
E Q E+S ++ LQ+QL ++K + + +LE LK +HL+E
Sbjct: 3127 EMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKE------ 3180
Query: 1544 ELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQK---NDGKEKEHEL 1600
L+ E+K E + + L S +KK +++ A E K ++ ++KE
Sbjct: 3181 -----LEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELE 3235
Query: 1601 HLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQ--- 1657
L SLE + +++ +++ K+ ES Q+ + + E + L+
Sbjct: 3236 DLKFSLE---SQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV 3292
Query: 1658 IMESQAEAFLKKLGLISRDPAAYPDMESDIRSWE----LFLSNVTKEIEKAKSQFEEQIK 1713
++ES+ + + R+ + ++S + + L ++ KE++K + +I
Sbjct: 3293 LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIV 3352
Query: 1714 AIKNGSRLSELSKVQ 1728
+ N + +L +Q
Sbjct: 3353 ELLNETEKYKLDSLQ 3367
Score = 33.9 bits (76), Expect = 1.7
Identities = 29/108 (26%), Positives = 60/108 (55%), Gaps = 16/108 (14%)
Query: 1517 KLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKK 1576
KLK L+++ + + L+ N++ K E++ Q+ E+E +QE +E+Q + + L+K+
Sbjct: 701 KLKDLQQSLVNSKSEEMTLQINELQK-EIEILRQE-EKEKGTLEQEVQELQLKTELLEKQ 758
Query: 1577 IKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIK 1624
+K+ ++ND +EK +L + S+ L +EK +E+ +K
Sbjct: 759 MKE---------KENDLQEKFAQLEAENSI-----LKDEKKTLEDMLK 792
Score = 32.0 bits (71), Expect = 6.3
Identities = 64/316 (20%), Positives = 126/316 (39%), Gaps = 59/316 (18%)
Query: 1473 IHQEVNTEPYNP---------FEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEE 1523
+++E++ + NP F+E + ++ + +V++ E+ E E K + LE
Sbjct: 896 LNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLEL 955
Query: 1524 TR---DLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLK-----K 1575
++ DL E+LK+ E + L E+K +QEK+++ R + L+
Sbjct: 956 SQRLSDLSEQLKQKHGE-----------ISFLNEEVKSLKQEKEQVSLRCRELEIIINHN 1004
Query: 1576 KIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDY---EE 1632
+ + V + + DG + S+ N E+ KI K E+ EE
Sbjct: 1005 RAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEE 1064
Query: 1633 SHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWEL 1692
S Q + + + KES + Q S+ + K+L ++ + D+ + + +
Sbjct: 1065 SKQEQLILD-HLPSVTKESSLRATQ--PSENDKLQKELNVLKSE---QNDLRLQMEAQRI 1118
Query: 1693 FLSNV------------TKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV 1740
LS V E +KA +E++ ++ EL K+ EL
Sbjct: 1119 CLSLVYSTHVDQVREYMENEKDKALCSLKEEL-IFAQEEKIKELQKIHQLELQ------- 1170
Query: 1741 HPELLPESSGDDGQGL 1756
+ + +GD+G+ L
Sbjct: 1171 --TMKTQETGDEGKPL 1184
Score = 32.0 bits (71), Expect = 6.3
Identities = 23/79 (29%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 1494 RIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLE 1553
++EK+ QV + LQ E + + K + E + E L+R LEE + +LD Q L+
Sbjct: 3371 QMEKDRQVHRKTLQTEQEANTEGQKK-MHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQ 3429
Query: 1554 REIKKWQQEKKEIQERLKS 1572
++++Q+++ E +E+ +S
Sbjct: 3430 GIMQEFQKQELEREEKRES 3448
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 57.4 bits (137), Expect = 1e-07
Identities = 68/300 (22%), Positives = 132/300 (44%), Gaps = 46/300 (15%)
Query: 1424 AHTVLSESNRNDEHCGNSNNKC--------------EVIPESTSAVTNIPHVQMVAIQVS 1469
AH +L+E NR N + E+ A T + VQ A +
Sbjct: 1443 AHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTA 1502
Query: 1470 WNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEE 1529
+ EV T Y +G ++ +E Q Q++ Q++ EQ+++ E+T+ +EE
Sbjct: 1503 REL---EVMTAKY------EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEE 1553
Query: 1530 KLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQ 1589
K+ + ++ SK + L+ ++ + + QQE + +Q +L L+ ++ + A+E Y
Sbjct: 1554 LSKKLADSDQASKVQ-QQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKL 1612
Query: 1590 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWK 1649
+ + + ++ Q+ E+ L + +E+ K+ KE E+ + + + L+ K
Sbjct: 1613 QMEKAKTHYDAKKQQNQELQEQLRS----LEQLQKENKELRAEAERLGHELQQAGLKT-K 1667
Query: 1650 ESE---------VYKLQIMESQAEAFLKKLG--------LISRDPAAYPDMESDIRSWEL 1692
E+E V L+ + A+ L+ LG L SR+P A P ++ I S +L
Sbjct: 1668 EAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDL 1727
Score = 41.2 bits (95), Expect = 0.010
Identities = 47/244 (19%), Positives = 102/244 (41%), Gaps = 23/244 (9%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETR---DLEEKLKRHLEENKISK 1542
+++ E R+ +E LQ+QLQ + E+ + K EE R D E+ +R + E K
Sbjct: 684 QQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAET 743
Query: 1543 TELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHL 1602
L +++ ++E+KE++E K ++ E + + + +E L
Sbjct: 744 RSL----------VEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRE----L 789
Query: 1603 DQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ 1662
+++ +T +E ++ + + +E YE+S Q E + + +
Sbjct: 790 AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQEL 849
Query: 1663 AEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLS 1722
EA K G+ S ++++ L+ ++++ E++++A K LS
Sbjct: 850 QEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQ------EKEVRAQKLADDLS 903
Query: 1723 ELSK 1726
L +
Sbjct: 904 TLQE 907
Score = 37.7 bits (86), Expect = 0.12
Identities = 60/275 (21%), Positives = 114/275 (41%), Gaps = 34/275 (12%)
Query: 1479 TEPYNP-FEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEE 1537
TEP P E + E+S++E++ Q Q+Q + L+R LE
Sbjct: 1115 TEPTGPKLEALRAEVSKLEQQCQKQQEQ----------------------ADSLERSLEA 1152
Query: 1538 NKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKE 1597
+ S+ E D L+ L+ ++++ QE Q L S ++++ + +++ D + K
Sbjct: 1153 ERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAED-EWKA 1211
Query: 1598 HELHLDQSLEISNTLTN---EKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKES-EV 1653
Q E N+L + E++ I KE + +R V AE + +E +
Sbjct: 1212 QVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRL 1271
Query: 1654 YKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIK 1713
+ + + A A + L + + E + E +T + E+A+ + +++K
Sbjct: 1272 LQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAE-ELGQELK 1330
Query: 1714 A--IKNGSRLSELSKVQISELSFPACNTVHPELLP 1746
A K + LS +Q+ S A + ELLP
Sbjct: 1331 AWQEKFFQKEQALSTLQLEHTSTQA---LVSELLP 1362
Score = 35.8 bits (81), Expect = 0.44
Identities = 48/239 (20%), Positives = 100/239 (41%), Gaps = 27/239 (11%)
Query: 1503 QDQLQEVYENYEQIKLKGLEETRDLEEKLKRHL-------------EENKISKTE-LDWF 1548
+DQ E ++K LEE R ++LK L + +TE
Sbjct: 1062 KDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPK 1121
Query: 1549 LQDLEREIKKWQQEKKEIQERLKSLKKKIK-----KVSNASEMYTQKNDGKEKEHELHLD 1603
L+ L E+ K +Q+ ++ QE+ SL++ ++ + S + T + +EK EL
Sbjct: 1122 LEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHS 1181
Query: 1604 QSLEIS--NTLTNEKMKIEEYIK---KGKEDYEESHQRAVAAEVSVLENWKESEVYKLQI 1658
QS S L + K++++ K + K Q A + +E + Q+
Sbjct: 1182 QSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQV 1241
Query: 1659 MESQAEA-FLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIK 1716
+E + E+ LK+L + + + +E +R + ++ + + S E++++++
Sbjct: 1242 LEKEGESKELKRLVMAESEKS--QKLEERLRLLQAETASNSARAAERSSALREEVQSLR 1298
Score = 31.6 bits (70), Expect = 8.3
Identities = 56/254 (22%), Positives = 105/254 (41%), Gaps = 48/254 (18%)
Query: 1475 QEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRH 1534
Q++ TE + +I+++ +E+ L +L+E + +Q L++ L
Sbjct: 300 QDLKTEK----SQMDRKINQLSEENGDLSFKLREFASHLQQ-----------LQDALNEL 344
Query: 1535 LEENKISKTELDWFLQD--LEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKND 1592
EE+ SK +W + LE+E+ Q+KK ++E+ + L+ K+ S E +Q D
Sbjct: 345 TEEH--SKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKL---SQLEEHLSQLQD 399
Query: 1593 GKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESE 1652
+E L L++ TL E AA ++ ++
Sbjct: 400 NPPQEKGEVLGDVLQL-ETLKQE-----------------------AATLAANNTQLQAR 435
Query: 1653 VYKLQIMESQAEA-FLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQ 1711
V L+ Q EA L + G + + +D++S LS +E+E+A +
Sbjct: 436 VEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGAR 495
Query: 1712 IKAIKNGSRLSELS 1725
+ A + S SEL+
Sbjct: 496 LTA-QVASLTSELT 508
Score = 31.6 bits (70), Expect = 8.3
Identities = 40/226 (17%), Positives = 88/226 (38%), Gaps = 35/226 (15%)
Query: 1475 QEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKL--KGLE-------ETR 1525
+E + EE+Q IS ++ E + L +Q + + E+ + KGLE E
Sbjct: 719 EEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAH 778
Query: 1526 DLE-EKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQER--------------- 1569
E E L+R L E ++ + + L +E+ W++ ++ Q+
Sbjct: 779 QAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTL 838
Query: 1570 ----------LKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKI 1619
L+ K+K+ + + SE+ + + E +L ++L+ K+
Sbjct: 839 KEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKL 898
Query: 1620 EEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEA 1665
+ + +E + + E V + ++ E ++++ A A
Sbjct: 899 ADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARA 944
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 57.0 bits (136), Expect = 2e-07
Identities = 57/251 (22%), Positives = 110/251 (43%), Gaps = 29/251 (11%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEET--------RDLEEKLKRHLEE 1537
E+ + + E + L+D+L + Q KLKG E+ +D +EKL+ L E
Sbjct: 23 EQAEADKKAAEDRSKQLEDELVSL-----QKKLKGTEDELDKYSEALKDAQEKLE--LAE 75
Query: 1538 NKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNAS----------EMY 1587
K + E D + L R I+ ++E QERL + +K+++ A+ E
Sbjct: 76 KKATDAEAD--VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
Query: 1588 TQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAE--VSVL 1645
QK++ K + E+ L ++ I+ + ++ + + D E + +RA +E + L
Sbjct: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
Query: 1646 ENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAK 1705
E ++ L+ +E+QAE + +K + D + + F ++EK+
Sbjct: 194 EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 253
Query: 1706 SQFEEQIKAIK 1716
EE++ K
Sbjct: 254 DDLEEKVAHAK 264
Score = 43.5 bits (101), Expect = 0.002
Identities = 36/159 (22%), Positives = 74/159 (46%), Gaps = 2/159 (1%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
EE + E+ +V++ + Q+ E E +++ L+E + + E R EE +
Sbjct: 114 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQ-LKEAKHIAEDADRKYEEVARKLVII 172
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQS 1605
+ L+ E + + + E++E LK++ +K + +E Y+QK D E+E ++ L
Sbjct: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV-LSDK 231
Query: 1606 LEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSV 1644
L+ + T + ++K +D EE A +S+
Sbjct: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
Score = 37.7 bits (86), Expect = 0.12
Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 22/127 (17%)
Query: 1429 SESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEER 1488
S+ R +E S KC + E VTN N+ E E Y+ E+
Sbjct: 174 SDLERAEERAELSEGKCAELEEELKTVTN-------------NLKSLEAQAEKYSQKED- 219
Query: 1489 QGEISRIEKEHQVLQDQLQEV---YENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
R E+E +VL D+L+E E E+ K + DLEEK+ EEN L
Sbjct: 220 -----RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
Query: 1546 DWFLQDL 1552
D L +L
Sbjct: 275 DQTLLEL 281
>gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 2 [Homo sapiens]
Length = 602
Score = 56.6 bits (135), Expect = 2e-07
Identities = 57/269 (21%), Positives = 125/269 (46%), Gaps = 42/269 (15%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEEN----KIS 1541
+ R EIS+++ + L+ Q ++V E+ K + + ++K KR LE I
Sbjct: 86 DSRSVEISQLKNTIKSLKQQKKQVEHQLEEEK-----KANNKKQKAKRVLEVQIQTLNIQ 140
Query: 1542 KTELDWFLQDLEREIKKWQQEKKEIQERLK------------------SLKKKIKKVSNA 1583
K EL+ L ++R ++ ++++ K++ RL+ + KKK ++S+
Sbjct: 141 KEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSR 200
Query: 1584 SEMYTQ-KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIK--KGKEDYEESHQRAVAA 1640
S+ T+ K + +E L Q + + +++ +EY + KG+ + R ++
Sbjct: 201 SKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQ 260
Query: 1641 EVSVLENWKESEVYKLQIMESQAEAFLKKLGL-ISRDPAAYPDMESDIRSWELFLSNVTK 1699
E+ L+ K+ ++ +++ +E ++ + +P A P E+ L ++ K
Sbjct: 261 EICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPS--------EVELQHLRK 312
Query: 1700 EIEKAKSQFEEQIKAIKNGSRLSELSKVQ 1728
E+E+ + + Q +KN R+S L++ Q
Sbjct: 313 ELERVAGELQAQ---VKNNQRISLLNQRQ 338
Score = 34.7 bits (78), Expect = 0.98
Identities = 58/263 (22%), Positives = 111/263 (42%), Gaps = 64/263 (24%)
Query: 1471 NIIHQEVNTEPYNP------FEERQGEISRIEKEHQVLQD-QLQEVYENYEQIKLKGLEE 1523
NI +E+NT+ Y+ FEE+ +++ + +H + + +L+ V N + K +
Sbjct: 138 NIQKEELNTDLYHMKRSLRYFEEKSKDLA-VRLQHSLQRKGELESVLSNVMATQKKKANQ 196
Query: 1524 TRD-----LEEKLKRHLEENKISKTEL--------------DWFLQDLEREIKKWQQEKK 1564
E KL++ + E + K +L D + + L+ E +WQQ +
Sbjct: 197 LSSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMR 256
Query: 1565 EIQERLKSLKKK--------------IKKVSN-ASEMYTQKNDGKEKEHEL-HLDQSLE- 1607
++ + + +LKK+ + K+ N +E + E EL HL + LE
Sbjct: 257 KMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER 316
Query: 1608 --------ISN----TLTNEKM-----KIEEYIKKGKEDYEESHQ--RAVAAEVSVLENW 1648
+ N +L N++ + EE ++K +E +E H+ + +A SV +
Sbjct: 317 VAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFKEP 376
Query: 1649 KESEVYKLQIMESQAEAFLKKLG 1671
LQ +E Q + +KLG
Sbjct: 377 NNENKNALQ-LEQQVKELQEKLG 398
>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 1 [Homo sapiens]
Length = 632
Score = 56.6 bits (135), Expect = 2e-07
Identities = 57/269 (21%), Positives = 125/269 (46%), Gaps = 42/269 (15%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEEN----KIS 1541
+ R EIS+++ + L+ Q ++V E+ K + + ++K KR LE I
Sbjct: 87 DSRSVEISQLKNTIKSLKQQKKQVEHQLEEEK-----KANNKKQKAKRVLEVQIQTLNIQ 141
Query: 1542 KTELDWFLQDLEREIKKWQQEKKEIQERLK------------------SLKKKIKKVSNA 1583
K EL+ L ++R ++ ++++ K++ RL+ + KKK ++S+
Sbjct: 142 KEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSR 201
Query: 1584 SEMYTQ-KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIK--KGKEDYEESHQRAVAA 1640
S+ T+ K + +E L Q + + +++ +EY + KG+ + R ++
Sbjct: 202 SKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQ 261
Query: 1641 EVSVLENWKESEVYKLQIMESQAEAFLKKLGL-ISRDPAAYPDMESDIRSWELFLSNVTK 1699
E+ L+ K+ ++ +++ +E ++ + +P A P E+ L ++ K
Sbjct: 262 EICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPS--------EVELQHLRK 313
Query: 1700 EIEKAKSQFEEQIKAIKNGSRLSELSKVQ 1728
E+E+ + + Q +KN R+S L++ Q
Sbjct: 314 ELERVAGELQAQ---VKNNQRISLLNQRQ 339
Score = 34.7 bits (78), Expect = 0.98
Identities = 58/263 (22%), Positives = 111/263 (42%), Gaps = 64/263 (24%)
Query: 1471 NIIHQEVNTEPYNP------FEERQGEISRIEKEHQVLQD-QLQEVYENYEQIKLKGLEE 1523
NI +E+NT+ Y+ FEE+ +++ + +H + + +L+ V N + K +
Sbjct: 139 NIQKEELNTDLYHMKRSLRYFEEKSKDLA-VRLQHSLQRKGELESVLSNVMATQKKKANQ 197
Query: 1524 TRD-----LEEKLKRHLEENKISKTEL--------------DWFLQDLEREIKKWQQEKK 1564
E KL++ + E + K +L D + + L+ E +WQQ +
Sbjct: 198 LSSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMR 257
Query: 1565 EIQERLKSLKKK--------------IKKVSN-ASEMYTQKNDGKEKEHEL-HLDQSLE- 1607
++ + + +LKK+ + K+ N +E + E EL HL + LE
Sbjct: 258 KMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELER 317
Query: 1608 --------ISN----TLTNEKM-----KIEEYIKKGKEDYEESHQ--RAVAAEVSVLENW 1648
+ N +L N++ + EE ++K +E +E H+ + +A SV +
Sbjct: 318 VAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFKEP 377
Query: 1649 KESEVYKLQIMESQAEAFLKKLG 1671
LQ +E Q + +KLG
Sbjct: 378 NNENKNALQ-LEQQVKELQEKLG 399
>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
[Homo sapiens]
Length = 580
Score = 56.2 bits (134), Expect = 3e-07
Identities = 60/253 (23%), Positives = 124/253 (49%), Gaps = 39/253 (15%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEEN----KIS 1541
+ R EIS+++ + L+ Q ++V E+ K + + ++K KR LE I
Sbjct: 87 DSRSVEISQLKNTIKSLKQQKKQVEHQLEEEK-----KANNKKQKAKRVLEVQIQTLNIQ 141
Query: 1542 KTELDWFLQDLEREIKKWQQEKKEIQERLK-SLKKKIKKVSNASE-MYTQK---NDGKEK 1596
K EL+ L ++R ++ ++++ K++ RL+ SL++K + S S M TQK N KE
Sbjct: 142 KEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQFKES 201
Query: 1597 EHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKL 1656
++ L++ E S L E+ + ++ ++K ++ E+ L+ K+ ++ ++
Sbjct: 202 FQQVQLERD-EYSEHLKGERARWQQRMRK------------MSQEICTLKKEKQQDMRRV 248
Query: 1657 QIMESQAEAFLKKLGL-ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAI 1715
+ +E ++ + +P A P E+ L ++ KE+E+ + + Q +
Sbjct: 249 EKLERSLSKLKNQMAEPLPPEPPAVPS--------EVELQHLRKELERVAGELQAQ---V 297
Query: 1716 KNGSRLSELSKVQ 1728
KN R+S L++ Q
Sbjct: 298 KNNQRISLLNQRQ 310
Score = 35.4 bits (80), Expect = 0.57
Identities = 41/217 (18%), Positives = 94/217 (43%), Gaps = 7/217 (3%)
Query: 1520 GLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKK 1579
G + RD R + + +L+ Q+ + E +++ +KSLK++ K+
Sbjct: 50 GCQPPRDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQ 109
Query: 1580 VSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVA 1639
V + E + N+ K+K + L+ ++ N + E++ + Y K Y E + +A
Sbjct: 110 VEHQLEEEKKANNKKQKAKRV-LEVQIQTLN-IQKEELNTDLYHMKRSLRYFEEKSKDLA 167
Query: 1640 AEVS-VLENWKESEVYKLQIMESQ---AEAFLKKLGLISRDPAAYPD-MESDIRSWELFL 1694
+ L+ E E +M +Q A F + + + Y + ++ + W+ +
Sbjct: 168 VRLQHSLQRKGELESVLSNVMATQKKKANQFKESFQQVQLERDEYSEHLKGERARWQQRM 227
Query: 1695 SNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISE 1731
+++EI K + ++ ++ ++ R K Q++E
Sbjct: 228 RKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAE 264
Score = 32.0 bits (71), Expect = 6.3
Identities = 48/242 (19%), Positives = 104/242 (42%), Gaps = 49/242 (20%)
Query: 1471 NIIHQEVNTEPYNP------FEERQGEISRIEKEHQVLQD-QLQEVYENYEQIKLKGLEE 1523
NI +E+NT+ Y+ FEE+ +++ + +H + + +L+ V N + K +
Sbjct: 139 NIQKEELNTDLYHMKRSLRYFEEKSKDLA-VRLQHSLQRKGELESVLSNVMATQKKKANQ 197
Query: 1524 TRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKK------- 1576
++ ++++ E D + + L+ E +WQQ +++ + + +LKK+
Sbjct: 198 FKESFQQVQ----------LERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRR 247
Query: 1577 -------IKKVSN-ASEMYTQKNDGKEKEHEL-HLDQSLE------ISNTLTNEKMKI-- 1619
+ K+ N +E + E EL HL + LE + N+++ +
Sbjct: 248 VEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLN 307
Query: 1620 ---EEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYK----LQIMESQAEAFLKKLGL 1672
EE I++ +E + +R S+ + K V+K L+ Q + +L L
Sbjct: 308 QRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFKEPEHLEAASQQNQQLTAQLSL 367
Query: 1673 IS 1674
++
Sbjct: 368 MA 369
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 56.2 bits (134), Expect = 3e-07
Identities = 69/278 (24%), Positives = 128/278 (46%), Gaps = 38/278 (13%)
Query: 1489 QGEISRIEKEHQ-------VLQDQLQ---EVYENYEQI------KLKGLEET-RDLEEKL 1531
+GE+ +E++HQ +L +QLQ E++ E++ K + LEE DLE ++
Sbjct: 872 EGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRV 931
Query: 1532 KRHLEENKI---SKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYT 1588
+ E N+I K ++ +QDLE ++ + + ++++Q + + KIKK+ +
Sbjct: 932 EEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLE 991
Query: 1589 QKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIK-KGKE-----DYEE--SHQRAVAA 1640
+N KE +L D+ E S+ L E+ K + K + K+ D EE +
Sbjct: 992 DQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ 1051
Query: 1641 EVSVLENWKESEVYKL--QIMESQAEAFLKKLGLISRD-----PAAYPDMESDIRSWELF 1693
E+ + + E L QI E QA+ KL L ++ A D E+ ++ L
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNAL- 1110
Query: 1694 LSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISE 1731
V +E++ ++ +E ++ K +E K +SE
Sbjct: 1111 --KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSE 1146
Score = 47.8 bits (112), Expect = 1e-04
Identities = 56/229 (24%), Positives = 106/229 (46%), Gaps = 42/229 (18%)
Query: 1517 KLKGLEETRDLEEKLKRHLEEN---KISKTELDWFLQDLEREIKKWQQEKKEIQERLKSL 1573
K+K L + EE+L+ EE K +T+++ L+++ER+ ++ +EK + E+L++
Sbjct: 840 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE 899
Query: 1574 KKKIKKVSN-ASEMYTQKNDGKEKEHEL--HLDQSLEISNTLTNEKMKIEEYIKKGKEDY 1630
+ + + + +K + +E H+L +++ E + L NEK K++ +I+ +E
Sbjct: 900 TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 1631 EESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSW 1690
+E +E KLQ+ + AEA +KK ME +I
Sbjct: 960 DE----------------EEGARQKLQLEKVTAEAKIKK-------------MEEEILLL 990
Query: 1691 ELFLSNVTKE-------IEKAKSQFEEQIKAIKNGSRLSELSKVQISEL 1732
E S KE I + SQ E+ + KN +++ +V IS+L
Sbjct: 991 EDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL 1039
Score = 46.2 bits (108), Expect = 3e-04
Identities = 65/332 (19%), Positives = 133/332 (40%), Gaps = 43/332 (12%)
Query: 1399 QIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNI 1458
Q+A E + + I K D L + + + + K + E+T I
Sbjct: 1014 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD--GETTDLQDQI 1071
Query: 1459 PHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEH----------QVLQDQLQE 1508
+Q ++ + +E EE QG ++R + E + LQ Q+ E
Sbjct: 1072 AELQAQIDELKLQLAKKE---------EELQGALARGDDETLHKNNALKVVRELQAQIAE 1122
Query: 1509 VYENYEQIKL---KGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKE 1565
+ E++E K K ++ RDL E+L + KTEL+ L + + + ++E
Sbjct: 1123 LQEDFESEKASRNKAEKQKRDLSEEL-------EALKTELEDTLDTTAAQQELRTKREQE 1175
Query: 1566 IQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKK 1625
+ E K+L+++ K + Q++ +E L+Q+ L K +
Sbjct: 1176 VAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL------ 1229
Query: 1626 GKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMES 1685
E+ + +A EV VL+ K +K + +++Q + K+ R + S
Sbjct: 1230 ------ETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKAS 1283
Query: 1686 DIRSWELFLSNVTKEIEKAKSQFEEQIKAIKN 1717
+++ +S + +E EK +F + ++++
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASLES 1315
Score = 46.2 bits (108), Expect = 3e-04
Identities = 56/266 (21%), Positives = 117/266 (43%), Gaps = 42/266 (15%)
Query: 1475 QEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRH 1534
QE+ T+ E + + K H+ Q+Q++ + + L+ L E + ++ K +
Sbjct: 1166 QELRTKREQEVAELKKALEEETKNHEA---QIQDMRQRHATA-LEELSEQLEQAKRFKAN 1221
Query: 1535 LEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGK 1594
LE+NK L+ ++L E+K QQ K E + + K L +++ E++ + ++G
Sbjct: 1222 LEKNKQG---LETDNKELACEVKVLQQVKAESEHKRKKLDAQVQ------ELHAKVSEGD 1272
Query: 1595 EKEHELHLDQSLEISNTLTNEKMKIEEYIKKG-------------KEDYEESHQRAVAAE 1641
EL +++ ++ N L N +EE KKG +D +E Q +
Sbjct: 1273 RLRVEL-AEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK 1331
Query: 1642 VSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEI 1701
+++ ++ E K + E Q E + A ++E + + + L++ K++
Sbjct: 1332 LNLSSRIRQLEEEKNSLQEQQEE-----------EEEARKNLEKQVLALQSQLADTKKKV 1380
Query: 1702 E----KAKSQFEEQIKAIKNGSRLSE 1723
+ +S E + K +K+ LS+
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQ 1406
Score = 44.7 bits (104), Expect = 0.001
Identities = 54/250 (21%), Positives = 106/250 (42%), Gaps = 43/250 (17%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEV----------YENYEQIKLKGLEETRDLEEKLKRHL 1535
EE + +EK+ LQ QL + E+ E+ K K L++ E L + L
Sbjct: 1353 EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDA----EALSQRL 1408
Query: 1536 EE-----NKISKTE--LDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYT 1588
EE +K+ KT+ L L DL ++ +Q ++++ K + + + + S Y
Sbjct: 1409 EEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYA 1468
Query: 1589 QKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKE---DYEE--SHQRAVAAEVS 1643
++ D E E ++L ++ L EE+ ++ K+ D E+ S + V V
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 1644 VLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEK 1703
LE K + +++ M +Q E ++E ++++ E + ++
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLE-----------------ELEDELQATEDAKLRLEVNMQA 1571
Query: 1704 AKSQFEEQIK 1713
K+QFE ++
Sbjct: 1572 MKAQFERDLQ 1581
Score = 37.4 bits (85), Expect = 0.15
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 1492 ISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQD 1551
+ R EK+ + + Q+++ + +Q K + +E+ ++LKR LEE + T + +
Sbjct: 1844 VRRTEKKLKEIFMQVEDERRHADQYK-EQMEKANARMKQLKRQLEEAEEEATRANASRRK 1902
Query: 1552 LEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLD-QSLEISN 1610
L+RE+ + + + + +LK ++++ S ++ G+ +LHL+ SLE+S+
Sbjct: 1903 LQRELDDATEANEGLSREVSTLKNRLRRGGPIS--FSSSRSGR---RQLHLEGASLELSD 1957
Query: 1611 TLTNEK 1616
T K
Sbjct: 1958 DDTESK 1963
Score = 37.0 bits (84), Expect = 0.20
Identities = 51/275 (18%), Positives = 125/275 (45%), Gaps = 45/275 (16%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVY-------------------------ENYEQIKLKGL 1521
E+Q E R + E L+D+LQ E E+ K +
Sbjct: 1538 EQQVEEMRTQLEE--LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLI 1595
Query: 1522 EETRDLEEKLKRHLEENKI---SKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIK 1578
++ R+LE +L+ ++ + SK +++ L+DLE +I+ + + E+ ++L+ L+ ++K
Sbjct: 1596 KQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMK 1655
Query: 1579 KV--------SNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDY 1630
++ E++ Q + ++K L + L++ L + + + + ++ +++
Sbjct: 1656 DYQRELEEARASRDEIFAQSKESEKKLKSLEA-EILQLQEELASSE-RARRHAEQERDEL 1713
Query: 1631 EESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSW 1690
+ + + + ++L+ + E ++ +E + E + L++ D ++ D +
Sbjct: 1714 ADEITNSASGKSALLDEKRRLEA-RIAQLEEELEEEQSNMELLN-DRFRKTTLQVDTLNA 1771
Query: 1691 ELFLS-NVTKEIEKAKSQFEEQIKAIKNGSRLSEL 1724
EL + ++ + A+ Q E Q K +K ++L EL
Sbjct: 1772 ELAAERSAAQKSDNARQQLERQNKELK--AKLQEL 1804
Score = 37.0 bits (84), Expect = 0.20
Identities = 50/253 (19%), Positives = 109/253 (43%), Gaps = 33/253 (13%)
Query: 1496 EKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLK---RHLEENKISKTELDWFLQDL 1552
+K+ ++ L+ E + + + +++ R L+ ++K R LEE + S+ E+ ++
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 1553 EREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTL 1612
E+++K + E ++QE L S SE + + + E + S + L
Sbjct: 1679 EKKLKSLEAEILQLQEELAS-----------SERARRHAEQERDELADEITNSASGKSAL 1727
Query: 1613 TNEKMKIEEYIKKGKEDYEESHQ---------RAVAAEVSVLE---NWKESEVYKLQIME 1660
+EK ++E I + +E+ EE R +V L + S K
Sbjct: 1728 LDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNAR 1787
Query: 1661 SQAEAFLKKLGLISRDPAAYPDMESDIRS-WELFLSNVTKEIEKAKSQFEEQIKAIKNGS 1719
Q E K+L A ++E ++S ++ +S + +I + + Q E++ K +
Sbjct: 1788 QQLERQNKEL------KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAAN 1841
Query: 1720 RLSELSKVQISEL 1732
+L ++ ++ E+
Sbjct: 1842 KLVRRTEKKLKEI 1854
Score = 32.0 bits (71), Expect = 6.3
Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 21/136 (15%)
Query: 1492 ISRIEKEHQVLQDQL-QEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ 1550
IS +E + L++QL QE E KL R E+KLK + + + D + +
Sbjct: 1816 ISALEAKIGQLEEQLEQEAKERAAANKL-----VRRTEKKLKEIFMQVEDERRHADQYKE 1870
Query: 1551 DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISN 1610
+E+ + +Q K++++E A E T+ N + K + LD + E +
Sbjct: 1871 QMEKANARMKQLKRQLEE--------------AEEEATRANASRRK-LQRELDDATEANE 1915
Query: 1611 TLTNEKMKIEEYIKKG 1626
L+ E ++ +++G
Sbjct: 1916 GLSREVSTLKNRLRRG 1931
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 56.2 bits (134), Expect = 3e-07
Identities = 93/399 (23%), Positives = 167/399 (41%), Gaps = 89/399 (22%)
Query: 1388 HHLNAE----NVAGHQIASETQILEGSLGISVKSHCS-TGDAHTVLSESNRNDEHCGNSN 1442
HHL E V+ + S + LE L I+ K+ C T + T + ESN+ +S
Sbjct: 318 HHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK--ARAAHSF 375
Query: 1443 NKCEVIPESTSAVTNIPHVQMVAIQ-VSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQV 1501
V+ E + V ++ + Q + N ++ T E++++ +V
Sbjct: 376 ----VVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEV 431
Query: 1502 LQDQLQEV--------YEN--YEQI--KLKGLE------------ETRDLE--------- 1528
++L++V YEN +E+I +LKG E E DLE
Sbjct: 432 ELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTS 491
Query: 1529 --------EKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEI-------QERLKSL 1573
+ LK LE K+ TEL L E K+ QE ++ QE + +
Sbjct: 492 EQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNN 551
Query: 1574 KKK----IKKVSNASEMYTQ--------KNDGKEKEHELH--LDQSLEISNTLTNEKMKI 1619
KK+ +K++ N E TQ + + K+K E+ LD+S E N L +
Sbjct: 552 KKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENK 611
Query: 1620 EEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQI--MESQAEAFLKKLGLISRDP 1677
+YI++ +++ + ++ A K+ VY++++ +E + E+ +K G I+
Sbjct: 612 NKYIEELQQENKALKKKGTAES-------KQLNVYEIKVNKLELELESAKQKFGEIT--- 661
Query: 1678 AAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIK 1716
+ +I ++ N+ +E+EKAK +E +K K
Sbjct: 662 ---DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQK 697
Score = 47.8 bits (112), Expect = 1e-04
Identities = 52/231 (22%), Positives = 102/231 (44%), Gaps = 11/231 (4%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+ +Q +I+ +K+ + + Q++ + E Q++ E + E+LK+ +E K +
Sbjct: 542 KNQQEDINNNKKQEERMLKQIENLQETETQLR----NELEYVREELKQKRDEVKCKLDKS 597
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQS 1605
+ +L ++++ + +E+Q+ K+LKKK S +Y K + E E E +
Sbjct: 598 EENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKF 657
Query: 1606 LEISNTLTNE---KMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ 1662
EI++T E K EE + + E + AV + + + + + +ME
Sbjct: 658 GEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKH 717
Query: 1663 AEAFLKKLGLISRDPAAYPDME---SDIR-SWELFLSNVTKEIEKAKSQFE 1709
+ K + + Y E S +R S E+ LSN+ E+ K Q E
Sbjct: 718 KHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLE 768
Score = 44.7 bits (104), Expect = 0.001
Identities = 69/316 (21%), Positives = 126/316 (39%), Gaps = 76/316 (24%)
Query: 1486 EERQGEISRIEKEHQVLQDQ---LQEVYENYEQIKLK---GLEETRDL--EEKLKRHL-- 1535
E RQ E S++++ ++++ Q +QE+ E++ LK G++E +DL E RHL
Sbjct: 126 ELRQKE-SKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNATRHLCN 184
Query: 1536 -------------EENKISKTELDWFLQDLEREIKKW---------QQEKKEIQERLKSL 1573
++ + + E DL I+K Q E ++ K L
Sbjct: 185 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFK-L 243
Query: 1574 KKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTN----------------EKM 1617
K+ +K+ + + Y ++ + KEK+ L L Q E N + + EK
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKT 303
Query: 1618 KI-----------EEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAF 1666
K+ + ++ K ED + S QR+V+ + ++ E+ + + Q+ E +
Sbjct: 304 KLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQM 363
Query: 1667 LKKLGLISRDPAAYPDMESDIRSWELFLSN--------------VTKEIEKAKSQFEEQI 1712
+ + + E+ + S E L +T E++K S+ EE
Sbjct: 364 EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMT 423
Query: 1713 KAIKNGS-RLSELSKV 1727
K N L EL KV
Sbjct: 424 KLTNNKEVELEELKKV 439
Score = 33.5 bits (75), Expect = 2.2
Identities = 57/212 (26%), Positives = 83/212 (39%), Gaps = 31/212 (14%)
Query: 1486 EERQGEISRI---EKEHQVLQDQLQEVYENYEQIKL---KGLEETRDLEEKLKRHLEENK 1539
EER E+ E+E L+ L+ N + L K LE R+ +EKLKR +EN
Sbjct: 726 EERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENT 785
Query: 1540 ISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHE 1599
+ E++ KK Q E E L K S +T + G K+
Sbjct: 786 ATLK---------EKKDKKTQTFLLETPEIYWKLDSKAVPSQTVSRNFTSVDHGISKDKR 836
Query: 1600 LHLDQSLEISNTL-----------TNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENW 1648
+L S + NTL T K K+++ E +R +A E + N
Sbjct: 837 DYLWTSAK--NTLSTPLPKAYTVKTPTKPKLQQRENLNIPIEESKKKRKMAFEFDI--NS 892
Query: 1649 KESEVYKLQIMESQAEAFLKKLGLISRDPAAY 1680
SE L M S+ E LK L + PA++
Sbjct: 893 DSSETTDLLSMVSEEET-LKTLYRNNNPPASH 923
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 56.2 bits (134), Expect = 3e-07
Identities = 51/244 (20%), Positives = 108/244 (44%), Gaps = 10/244 (4%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
E+ +I I K L++QL + +I+ + E+ D+ E +K+H + +L
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIK--KVSNASEMYTQKNDGKEKEHELHLD 1603
+ DL+ ++++ +EK+E+QE+L++L+ +++ + S + + + K +E L+
Sbjct: 1774 AQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRE----LE 1828
Query: 1604 QSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQA 1663
LE T + +K+ E E + +AAE E K + E
Sbjct: 1829 TRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMG 1888
Query: 1664 EAFLKKLGLISRDPAAYPDMES---DIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSR 1720
E K+ + D+ES +S + L K I ++ E+++++ +N
Sbjct: 1889 ELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDL 1948
Query: 1721 LSEL 1724
++ L
Sbjct: 1949 INSL 1952
Score = 36.6 bits (83), Expect = 0.26
Identities = 39/202 (19%), Positives = 89/202 (44%), Gaps = 40/202 (19%)
Query: 1530 KLKRHLEENKIS-------KTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSN 1582
+LK LEE++ + + ++ ++DL +I + K ++E+L L+++ ++ N
Sbjct: 1687 QLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQN 1746
Query: 1583 ASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEV 1642
E + + K+H+ + Q+ + + + ++EE K K++ +E
Sbjct: 1747 RLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE-ANKEKQELQE---------- 1795
Query: 1643 SVLENWKESEVYKLQIMESQAEAFLKKL---GLISRDPAAYPDME-------SDIRSWEL 1692
KLQ ++SQ E + + L+SR A ++E + ++ E
Sbjct: 1796 ------------KLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLES 1843
Query: 1693 FLSNVTKEIEKAKSQFEEQIKA 1714
S + + +EK + +++I A
Sbjct: 1844 LASRLKENMEKLTEERDQRIAA 1865
Score = 35.0 bits (79), Expect = 0.75
Identities = 55/264 (20%), Positives = 112/264 (42%), Gaps = 33/264 (12%)
Query: 1527 LEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVS----- 1581
L+++ + LE + +K +L+ L DL Q + +E Q L+ LKKK ++++
Sbjct: 1389 LQQEFEDKLEVEQQNKRQLERRLGDL-------QADSEESQRALQQLKKKCQRLTAELQD 1441
Query: 1582 -----NASEMYTQKNDGKEKEHELHLDQSLEIS--NTLTNEKMKIEEYIKKG-----KED 1629
++ + + K++ + L Q+ E + L EK++ E+ + K+
Sbjct: 1442 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQ 1501
Query: 1630 YEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRD-PAAYPDMESDIR 1688
EE V+ E+E+ + ES+ EA L K+ RD A D E ++
Sbjct: 1502 LEEKDMDIAGFTQKVVS--LEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1559
Query: 1689 SWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPAC--NTVHPELLP 1746
+ + +E+AK + E +++ ++ S+ + E + +C E+
Sbjct: 1560 E----QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQL 1615
Query: 1747 ESSGDDGQGLVTSASDVTGNHAAL 1770
E +D Q ++ ++ G A L
Sbjct: 1616 EEEYEDKQKVLREKRELEGKLATL 1639
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 56.2 bits (134), Expect = 3e-07
Identities = 36/129 (27%), Positives = 69/129 (53%), Gaps = 5/129 (3%)
Query: 221 TQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQ 280
+ S + + + + +K +GN +E + A+ YT+AIE P N + Y NRA + G
Sbjct: 75 SNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGH 134
Query: 281 FRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLI 340
+ +A+ D ++A + + + K + R AL+ L +++ A+ + KA L DPE D
Sbjct: 135 YTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDL---DPE--NDSY 189
Query: 341 QQHVKLQKQ 349
+ ++K+ +Q
Sbjct: 190 KSNLKIAEQ 198
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 55.8 bits (133), Expect = 4e-07
Identities = 65/308 (21%), Positives = 134/308 (43%), Gaps = 46/308 (14%)
Query: 1440 NSNNKCEVIP----------ESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPY------- 1482
NS +CE I E+ + + VQ++ +Q + ++ +E+ E
Sbjct: 1056 NSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIK 1115
Query: 1483 ------NPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLE 1536
N EE Q ++ + +K+ Q +L+ V ++ +Q L +E E+L + L
Sbjct: 1116 EHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIAD--YERLMKELN 1173
Query: 1537 ENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASE------MYTQK 1590
+ +K ++DLE+EIK +Q+++ +QE + SL+ +++ + + T+K
Sbjct: 1174 QKLTNKNNK---IEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKK 1230
Query: 1591 N--DGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENW 1648
D K+ E + HL + L + ++E Y + E E H+ + S ++
Sbjct: 1231 ELADSKQAETD-HLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQ 1289
Query: 1649 KESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQF 1708
+ Y+ ++ Q E K A + S+ S+++ + NV K+ +K KS
Sbjct: 1290 RTLSAYQQRVTALQEECRAAK--------AEQATVTSEFESYKVRVHNVLKQ-QKNKSMS 1340
Query: 1709 EEQIKAIK 1716
+ + + K
Sbjct: 1341 QAETEGAK 1348
Score = 51.2 bits (121), Expect = 1e-05
Identities = 59/246 (23%), Positives = 107/246 (43%), Gaps = 35/246 (14%)
Query: 1477 VNTEPYNPFEERQGEISRIEKEHQVLQ------DQLQEVYENYEQIKLKGLEETRDLEEK 1530
V T+ Y +E E+S +E V+ + L ++ E + + E+ +LE++
Sbjct: 755 VKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKE 814
Query: 1531 LKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQK 1590
+K EE+ + EL L+D E+E ++E +EIQ ++L+ + ++ NA
Sbjct: 815 IKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNA------- 867
Query: 1591 NDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKE 1650
N+ E++ L Q E+S T + E H + EN K
Sbjct: 868 NEKTRLENQNLLIQVEEVSQTCSK----------------SEIHNEKEKCFIKEHENLKP 911
Query: 1651 SEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEE 1710
K ++ + +AE L K L ++ P+ D S ++ E + N+ KE ++ EE
Sbjct: 912 LLEQK-ELRDRRAELILLKDSL-AKSPSVKNDPLSSVKELEEKIENLEKECKEK----EE 965
Query: 1711 QIKAIK 1716
+I IK
Sbjct: 966 KINKIK 971
Score = 47.4 bits (111), Expect = 1e-04
Identities = 50/248 (20%), Positives = 115/248 (46%), Gaps = 2/248 (0%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
+E +G+I+ + +E ++L+ +E + K E R + E L + +E+ +EL
Sbjct: 583 KELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILE-LGKKVEQTIQYNSEL 641
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQS 1605
+ + +L +++ +EK + ++L+ L ++K +S E+ + + +E+ +
Sbjct: 642 EQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEK 701
Query: 1606 LEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEA 1665
++S L + E+ I K E + + E L E+E + +++Q
Sbjct: 702 KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYG 761
Query: 1666 FLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSR-LSEL 1724
FLK++G + + D+ + +++ L+ + +E Q +E++ ++ + L E
Sbjct: 762 FLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEE 821
Query: 1725 SKVQISEL 1732
S VQ EL
Sbjct: 822 SVVQCEEL 829
Score = 47.0 bits (110), Expect = 2e-04
Identities = 64/288 (22%), Positives = 135/288 (46%), Gaps = 25/288 (8%)
Query: 1476 EVNTEPYNPFEERQGEISRIEKEHQVLQ-------DQLQEVYENYEQIKL---KGLEETR 1525
++N E N +R ++ +EKE + LQ ++L+ + +YEQ K+ K LEE +
Sbjct: 792 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ 851
Query: 1526 DLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASE 1585
+E L+ L E K + + Q+L ++++ Q + + + K IK+ N
Sbjct: 852 SEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP 911
Query: 1586 MYTQKNDGKEKEHELHLDQSLEISNTLTNEKM----KIEEYIKKGKEDYEESHQRAVAAE 1641
+ QK + + L SL S ++ N+ + ++EE I+ +++ +E ++ +
Sbjct: 912 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIK 971
Query: 1642 VSVLENWKE--SEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTK 1699
+ ++ KE S + Q ++ + E+ + +S A+ D+ S++ N+
Sbjct: 972 LVAVKAKKELDSSRKETQTVKEELESLRSEKDQLS---ASMRDLIQGAESYK----NLLL 1024
Query: 1700 EIEKAKSQFE-EQIKAIKNGSRLSELSK-VQISELSFPACNTVHPELL 1745
E EK Q + E+ +A R+ +L++ ++ S L N+ + +LL
Sbjct: 1025 EYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLL 1072
Score = 39.3 bits (90), Expect = 0.040
Identities = 51/258 (19%), Positives = 122/258 (47%), Gaps = 13/258 (5%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEET--RDLEEKLKRHLEENKISKT 1543
EE+ I +++ E L Q E + + +++ L+E +++ E + L +++ K
Sbjct: 395 EEQGCVIEKLKSELAGLNKQFCYTVEQHNR-EVQSLKEQHQKEISELNETFLSDSEKEKL 453
Query: 1544 ELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIK----KVSNASEMYTQKNDGKEKEHE 1599
L + +Q L+ + + QQEK+E +SL++ ++ ++ ++ +Q+ + +++
Sbjct: 454 TLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQA 513
Query: 1600 LHLDQSLEISNTLTNEKMKIEEYIKK--GKEDYEESHQRAVAAEVSVLENWKESE-VYKL 1656
+ + + T EK + E + + G+ + S Q V + ++N +E VY L
Sbjct: 514 SDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLL 573
Query: 1657 QIMESQAEAFLKKL-GLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAI 1715
+ SQ + LK+L G I+ D + +++ + N K+ E+ + E K +
Sbjct: 574 SL--SQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKV 631
Query: 1716 KNGSRLSELSKVQISELS 1733
+ + + + +++EL+
Sbjct: 632 EQTIQYNSELEQKVNELT 649
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 55.5 bits (132), Expect = 5e-07
Identities = 51/263 (19%), Positives = 129/263 (49%), Gaps = 25/263 (9%)
Query: 1483 NPFEERQGEISRIEKEHQVLQDQLQ---EVYENYEQIKLKGLEETRDLEE---KLKRHLE 1536
N +E + + S++ +E +LQ+QLQ E+Y E+++++ + ++LEE +++ LE
Sbjct: 873 NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLE 932
Query: 1537 ENK-------ISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQ 1589
E + + ++ + DLE ++++ + ++++Q + + KIKK+ + +
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 992
Query: 1590 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWK 1649
+N+ KE +L ++ +++ L E+ K + K ++ ++ +E+ V +
Sbjct: 993 QNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL------KNKHESMISELEVRLKKE 1046
Query: 1650 ESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFE 1709
E +L+ ++ + E G S D+++ I ++ L+ +E++ A ++ +
Sbjct: 1047 EKSRQELEKLKRKLE------GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1100
Query: 1710 EQIKAIKNGSRLSELSKVQISEL 1732
++I N + + IS+L
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDL 1123
Score = 54.7 bits (130), Expect = 9e-07
Identities = 58/264 (21%), Positives = 118/264 (44%), Gaps = 36/264 (13%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVYENYEQ---------IKLKGLEETR-----------D 1526
E +G+ ++ K+ L QLQ+ E ++ KL+ LEE R +
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1357
Query: 1527 LEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEM 1586
++ L+RH+ I ++ LQD ++ ++ KK Q+ +++L ++ ++ + A +
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417
Query: 1587 YTQKNDGKEKEHE---LHLDQSLEISNTLTNEKMKIEEYIKKGK---EDYEESHQRAVAA 1640
+ + ++E + + LD ++ + L ++ K ++ + + K Y + RA A
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
Query: 1641 EVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKE 1700
+E E L + + EA K L + +ME + S + NV E
Sbjct: 1478 A-------REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV-HE 1529
Query: 1701 IEKAKSQFEEQIKAIKNGSRLSEL 1724
+EK+K E Q++ +K ++L EL
Sbjct: 1530 LEKSKRALETQMEEMK--TQLEEL 1551
Score = 45.8 bits (107), Expect = 4e-04
Identities = 49/239 (20%), Positives = 112/239 (46%), Gaps = 28/239 (11%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ 1550
+++R E+E Q +D+LQ+ E + K E ++LE+K + EE + + +L
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQ----KAENELKELEQKHSQLTEEKNLLQEQLQ---- 897
Query: 1551 DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISN 1610
E E+ E +E++ RL + K++++++ + EM + + +++ +L ++
Sbjct: 898 -AETEL---YAEAEEMRVRLAAKKQELEEILH--EMEARLEEEEDRGQQLQAER-----K 946
Query: 1611 TLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKL 1670
+ + + +EE +++ + ++ V AE + + E E+ +M+ Q K+
Sbjct: 947 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK--LEDEIL---VMDDQNNKLSKER 1001
Query: 1671 GLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEE-QIKAIKNGSRLSELSKVQ 1728
L+ D+ +++ E N+TK K +S E +++ K EL K++
Sbjct: 1002 KLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLK 1057
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/242 (21%), Positives = 102/242 (42%), Gaps = 23/242 (9%)
Query: 1496 EKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLER- 1554
E+E VL+ L E ++E + ++ E+L LE+ K +K LD Q LE+
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 1555 ------EIKKWQQEKKEIQERLKSLKKKIKKV-SNASEMYTQKNDGKEKEHEL--HLDQS 1605
E++ Q K+E++ + K L+ +++++ S S+ + + +K H+L ++
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 1606 LEISNTLTNEKMKIEE---YIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ 1662
+ N + +K+ + + +D +E Q +++V ++ E + + +
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1352
Query: 1663 AEAFLKKLGL----------ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQI 1712
E K L +S D S + + E KEIE Q+EE+
Sbjct: 1353 DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 1412
Query: 1713 KA 1714
A
Sbjct: 1413 AA 1414
Score = 40.4 bits (93), Expect = 0.018
Identities = 61/268 (22%), Positives = 115/268 (42%), Gaps = 25/268 (9%)
Query: 1471 NIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQE---VYENYEQIKLKGLEETRDL 1527
N + QE++ + +RQ +S +EK+ + L E + Y + + E R+
Sbjct: 1423 NRLQQELDDLVVDLDNQRQ-LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1481
Query: 1528 EEK---LKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNAS 1584
E K L R LEE +K EL+ + L+ E++ K ++ + + L+K K + +
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK--SKRALET 1539
Query: 1585 EMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSV 1644
+M K +E E EL + + K+++E ++ K +E R + A
Sbjct: 1540 QMEEMKTQLEELEDELQATE---------DAKLRLEVNMQALKGQFE----RDLQARDEQ 1586
Query: 1645 LENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKA 1704
E + +L E++ E K+ L + AA +E D++ EL + K E+A
Sbjct: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAA---AAKKKLEGDLKDLELQADSAIKGREEA 1643
Query: 1705 KSQFEEQIKAIKNGSRLSELSKVQISEL 1732
Q + +K+ R E ++ E+
Sbjct: 1644 IKQLRKLQAQMKDFQRELEDARASRDEI 1671
Score = 39.7 bits (91), Expect = 0.030
Identities = 55/246 (22%), Positives = 106/246 (43%), Gaps = 27/246 (10%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIK-----LKGLEETRDLEEKLKRHL-EENK 1539
EE Q ++R++ E + L+++ E I L R+ EK KR L EE +
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 1540 ISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHE 1599
KTEL+ L + Q+ + + ++ + LKK + + + + E Q+ K +
Sbjct: 1150 ALKTELEDTLDSTATQ----QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 1600 LHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIM 1659
L + LE + + + + K K+ E+ + +A E+ VL K+ +K + +
Sbjct: 1206 EELTEQLE-------QFKRAKANLDKNKQTLEKEN-ADLAGELRVLGQAKQEVEHKKKKL 1257
Query: 1660 ESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGS 1719
E+Q + K S A ++ + + + +VT + +A+ KAIK
Sbjct: 1258 EAQVQELQSK---CSDGERARAELNDKVHKLQNEVESVTGMLNEAEG------KAIKLAK 1308
Query: 1720 RLSELS 1725
++ LS
Sbjct: 1309 DVASLS 1314
Score = 36.6 bits (83), Expect = 0.26
Identities = 32/155 (20%), Positives = 73/155 (47%), Gaps = 19/155 (12%)
Query: 1478 NTEPYNPFEERQGEI-SRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLE 1536
N E + E +G + S+ + L+ ++ ++ E EQ + T+ L++K K+ E
Sbjct: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
Query: 1537 ENKISKTELDWFLQDLEREIKKWQQEKKEIQE---RLKSLKKKIKKVSNASEMYTQKNDG 1593
L +E E K +Q K++ ++ R+K LK+++++ S Q+ +
Sbjct: 1854 -----------ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES----QRINA 1898
Query: 1594 KEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKE 1628
++ + LD++ E + + E ++ +++G E
Sbjct: 1899 NRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
Score = 35.4 bits (80), Expect = 0.57
Identities = 35/164 (21%), Positives = 71/164 (43%), Gaps = 1/164 (0%)
Query: 1489 QGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWF 1548
Q E R+E L+++L+E N E + + + T+ E+ L L + + + +
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ-LSNELATERSTAQKNESA 1786
Query: 1549 LQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEI 1608
Q LER+ K+ + + E++ +KS K A ++ +E + +SL+
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Query: 1609 SNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESE 1652
+ E + E +K E Y+E ++ A + +E+E
Sbjct: 1847 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
Score = 34.7 bits (78), Expect = 0.98
Identities = 42/246 (17%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ 1550
++ ++ + + L+D+LQ + ++++ E L+ E+N+ + +L L
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 1551 DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISN 1610
+ E E+ + E+K Q L + KK K +G K+ EL D +++
Sbjct: 1600 EYETEL---EDERK--QRALAAAAKK-------------KLEGDLKDLELQADSAIKGRE 1641
Query: 1611 TLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ-----AEA 1665
+ K++ +K + + E++ + EN K+++ + +M+ Q AE
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 1666 FLKKLGL--------ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKN 1717
K+ L ++ + ++ + R E ++ + +E+E+ + E ++
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Query: 1718 GSRLSE 1723
++ +E
Sbjct: 1762 ATQQAE 1767
Score = 32.3 bits (72), Expect = 4.8
Identities = 28/165 (16%), Positives = 74/165 (44%), Gaps = 8/165 (4%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
E+ E++ Q + Q++ ++++ K E ++ K K + + +L
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMY---TQKNDGKEKEHELHL 1602
+ ++ RE + + K+ ++LK + +++ +E Y +K + + K+ + L
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 1603 DQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLEN 1647
+++ E S + + K++ + + E E A+ EV+ L++
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNE-----AMGREVNALKS 1926
Score = 32.3 bits (72), Expect = 4.8
Identities = 23/111 (20%), Positives = 59/111 (53%), Gaps = 4/111 (3%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVYENY---EQIKLKGLEETRDLEEKLKRHLEENKISKT 1543
E+Q ++++ + L++ L +V + EQ K + E+ ++LKR LEE +
Sbjct: 1836 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA-EKGNARVKQLKRQLEEAEEESQ 1894
Query: 1544 ELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGK 1594
++ + L+RE+ + + + + + +LK K+++ + S + ++++ G+
Sbjct: 1895 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGR 1945
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 55.5 bits (132), Expect = 5e-07
Identities = 51/263 (19%), Positives = 129/263 (49%), Gaps = 25/263 (9%)
Query: 1483 NPFEERQGEISRIEKEHQVLQDQLQ---EVYENYEQIKLKGLEETRDLEE---KLKRHLE 1536
N +E + + S++ +E +LQ+QLQ E+Y E+++++ + ++LEE +++ LE
Sbjct: 880 NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLE 939
Query: 1537 ENK-------ISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQ 1589
E + + ++ + DLE ++++ + ++++Q + + KIKK+ + +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 999
Query: 1590 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWK 1649
+N+ KE +L ++ +++ L E+ K + K ++ ++ +E+ V +
Sbjct: 1000 QNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL------KNKHESMISELEVRLKKE 1053
Query: 1650 ESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFE 1709
E +L+ ++ + E G S D+++ I ++ L+ +E++ A ++ +
Sbjct: 1054 EKSRQELEKLKRKLE------GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 1710 EQIKAIKNGSRLSELSKVQISEL 1732
++I N + + IS+L
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDL 1130
Score = 54.7 bits (130), Expect = 9e-07
Identities = 58/264 (21%), Positives = 118/264 (44%), Gaps = 36/264 (13%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVYENYEQ---------IKLKGLEETR-----------D 1526
E +G+ ++ K+ L QLQ+ E ++ KL+ LEE R +
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364
Query: 1527 LEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEM 1586
++ L+RH+ I ++ LQD ++ ++ KK Q+ +++L ++ ++ + A +
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424
Query: 1587 YTQKNDGKEKEHE---LHLDQSLEISNTLTNEKMKIEEYIKKGK---EDYEESHQRAVAA 1640
+ + ++E + + LD ++ + L ++ K ++ + + K Y + RA A
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484
Query: 1641 EVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKE 1700
+E E L + + EA K L + +ME + S + NV E
Sbjct: 1485 A-------REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV-HE 1536
Query: 1701 IEKAKSQFEEQIKAIKNGSRLSEL 1724
+EK+K E Q++ +K ++L EL
Sbjct: 1537 LEKSKRALETQMEEMK--TQLEEL 1558
Score = 45.8 bits (107), Expect = 4e-04
Identities = 49/239 (20%), Positives = 112/239 (46%), Gaps = 28/239 (11%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ 1550
+++R E+E Q +D+LQ+ E + K E ++LE+K + EE + + +L
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQ----KAENELKELEQKHSQLTEEKNLLQEQLQ---- 904
Query: 1551 DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISN 1610
E E+ E +E++ RL + K++++++ + EM + + +++ +L ++
Sbjct: 905 -AETEL---YAEAEEMRVRLAAKKQELEEILH--EMEARLEEEEDRGQQLQAER-----K 953
Query: 1611 TLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKL 1670
+ + + +EE +++ + ++ V AE + + E E+ +M+ Q K+
Sbjct: 954 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK--LEDEIL---VMDDQNNKLSKER 1008
Query: 1671 GLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEE-QIKAIKNGSRLSELSKVQ 1728
L+ D+ +++ E N+TK K +S E +++ K EL K++
Sbjct: 1009 KLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLK 1064
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/242 (21%), Positives = 102/242 (42%), Gaps = 23/242 (9%)
Query: 1496 EKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLER- 1554
E+E VL+ L E ++E + ++ E+L LE+ K +K LD Q LE+
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 1555 ------EIKKWQQEKKEIQERLKSLKKKIKKV-SNASEMYTQKNDGKEKEHEL--HLDQS 1605
E++ Q K+E++ + K L+ +++++ S S+ + + +K H+L ++
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Query: 1606 LEISNTLTNEKMKIEE---YIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ 1662
+ N + +K+ + + +D +E Q +++V ++ E + + +
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1359
Query: 1663 AEAFLKKLGL----------ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQI 1712
E K L +S D S + + E KEIE Q+EE+
Sbjct: 1360 DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 1419
Query: 1713 KA 1714
A
Sbjct: 1420 AA 1421
Score = 40.4 bits (93), Expect = 0.018
Identities = 61/268 (22%), Positives = 115/268 (42%), Gaps = 25/268 (9%)
Query: 1471 NIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQE---VYENYEQIKLKGLEETRDL 1527
N + QE++ + +RQ +S +EK+ + L E + Y + + E R+
Sbjct: 1430 NRLQQELDDLVVDLDNQRQ-LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1488
Query: 1528 EEK---LKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNAS 1584
E K L R LEE +K EL+ + L+ E++ K ++ + + L+K K + +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK--SKRALET 1546
Query: 1585 EMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSV 1644
+M K +E E EL + + K+++E ++ K +E R + A
Sbjct: 1547 QMEEMKTQLEELEDELQATE---------DAKLRLEVNMQALKGQFE----RDLQARDEQ 1593
Query: 1645 LENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKA 1704
E + +L E++ E K+ L + AA +E D++ EL + K E+A
Sbjct: 1594 NEEKRRQLQRQLHEYETELEDERKQRALAA---AAKKKLEGDLKDLELQADSAIKGREEA 1650
Query: 1705 KSQFEEQIKAIKNGSRLSELSKVQISEL 1732
Q + +K+ R E ++ E+
Sbjct: 1651 IKQLRKLQAQMKDFQRELEDARASRDEI 1678
Score = 39.7 bits (91), Expect = 0.030
Identities = 55/246 (22%), Positives = 106/246 (43%), Gaps = 27/246 (10%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIK-----LKGLEETRDLEEKLKRHL-EENK 1539
EE Q ++R++ E + L+++ E I L R+ EK KR L EE +
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 1540 ISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHE 1599
KTEL+ L + Q+ + + ++ + LKK + + + + E Q+ K +
Sbjct: 1157 ALKTELEDTLDSTATQ----QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 1600 LHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIM 1659
L + LE + + + + K K+ E+ + +A E+ VL K+ +K + +
Sbjct: 1213 EELTEQLE-------QFKRAKANLDKNKQTLEKEN-ADLAGELRVLGQAKQEVEHKKKKL 1264
Query: 1660 ESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGS 1719
E+Q + K S A ++ + + + +VT + +A+ KAIK
Sbjct: 1265 EAQVQELQSK---CSDGERARAELNDKVHKLQNEVESVTGMLNEAEG------KAIKLAK 1315
Query: 1720 RLSELS 1725
++ LS
Sbjct: 1316 DVASLS 1321
Score = 36.6 bits (83), Expect = 0.26
Identities = 32/155 (20%), Positives = 73/155 (47%), Gaps = 19/155 (12%)
Query: 1478 NTEPYNPFEERQGEI-SRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLE 1536
N E + E +G + S+ + L+ ++ ++ E EQ + T+ L++K K+ E
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860
Query: 1537 ENKISKTELDWFLQDLEREIKKWQQEKKEIQE---RLKSLKKKIKKVSNASEMYTQKNDG 1593
L +E E K +Q K++ ++ R+K LK+++++ S Q+ +
Sbjct: 1861 -----------ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES----QRINA 1905
Query: 1594 KEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKE 1628
++ + LD++ E + + E ++ +++G E
Sbjct: 1906 NRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Score = 35.4 bits (80), Expect = 0.57
Identities = 35/164 (21%), Positives = 71/164 (43%), Gaps = 1/164 (0%)
Query: 1489 QGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWF 1548
Q E R+E L+++L+E N E + + + T+ E+ L L + + + +
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ-LSNELATERSTAQKNESA 1793
Query: 1549 LQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEI 1608
Q LER+ K+ + + E++ +KS K A ++ +E + +SL+
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Query: 1609 SNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESE 1652
+ E + E +K E Y+E ++ A + +E+E
Sbjct: 1854 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1897
Score = 34.7 bits (78), Expect = 0.98
Identities = 42/246 (17%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ 1550
++ ++ + + L+D+LQ + ++++ E L+ E+N+ + +L L
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 1551 DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISN 1610
+ E E+ + E+K Q L + KK K +G K+ EL D +++
Sbjct: 1607 EYETEL---EDERK--QRALAAAAKK-------------KLEGDLKDLELQADSAIKGRE 1648
Query: 1611 TLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ-----AEA 1665
+ K++ +K + + E++ + EN K+++ + +M+ Q AE
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 1666 FLKKLGL--------ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKN 1717
K+ L ++ + ++ + R E ++ + +E+E+ + E ++
Sbjct: 1709 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1768
Query: 1718 GSRLSE 1723
++ +E
Sbjct: 1769 ATQQAE 1774
Score = 32.3 bits (72), Expect = 4.8
Identities = 28/165 (16%), Positives = 74/165 (44%), Gaps = 8/165 (4%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
E+ E++ Q + Q++ ++++ K E ++ K K + + +L
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMY---TQKNDGKEKEHELHL 1602
+ ++ RE + + K+ ++LK + +++ +E Y +K + + K+ + L
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Query: 1603 DQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLEN 1647
+++ E S + + K++ + + E E A+ EV+ L++
Sbjct: 1894 EEAEEESQRINANRRKLQRELDEATESNE-----AMGREVNALKS 1933
Score = 32.3 bits (72), Expect = 4.8
Identities = 23/111 (20%), Positives = 59/111 (53%), Gaps = 4/111 (3%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVYENY---EQIKLKGLEETRDLEEKLKRHLEENKISKT 1543
E+Q ++++ + L++ L +V + EQ K + E+ ++LKR LEE +
Sbjct: 1843 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA-EKGNARVKQLKRQLEEAEEESQ 1901
Query: 1544 ELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGK 1594
++ + L+RE+ + + + + + +LK K+++ + S + ++++ G+
Sbjct: 1902 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGR 1952
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 55.5 bits (132), Expect = 5e-07
Identities = 51/263 (19%), Positives = 129/263 (49%), Gaps = 25/263 (9%)
Query: 1483 NPFEERQGEISRIEKEHQVLQDQLQ---EVYENYEQIKLKGLEETRDLEE---KLKRHLE 1536
N +E + + S++ +E +LQ+QLQ E+Y E+++++ + ++LEE +++ LE
Sbjct: 880 NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLE 939
Query: 1537 ENK-------ISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQ 1589
E + + ++ + DLE ++++ + ++++Q + + KIKK+ + +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 999
Query: 1590 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWK 1649
+N+ KE +L ++ +++ L E+ K + K ++ ++ +E+ V +
Sbjct: 1000 QNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL------KNKHESMISELEVRLKKE 1053
Query: 1650 ESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFE 1709
E +L+ ++ + E G S D+++ I ++ L+ +E++ A ++ +
Sbjct: 1054 EKSRQELEKLKRKLE------GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLD 1107
Query: 1710 EQIKAIKNGSRLSELSKVQISEL 1732
++I N + + IS+L
Sbjct: 1108 DEIAQKNNALKKIRELEGHISDL 1130
Score = 54.7 bits (130), Expect = 9e-07
Identities = 58/264 (21%), Positives = 118/264 (44%), Gaps = 36/264 (13%)
Query: 1487 ERQGEISRIEKEHQVLQDQLQEVYENYEQ---------IKLKGLEETR-----------D 1526
E +G+ ++ K+ L QLQ+ E ++ KL+ LEE R +
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364
Query: 1527 LEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEM 1586
++ L+RH+ I ++ LQD ++ ++ KK Q+ +++L ++ ++ + A +
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424
Query: 1587 YTQKNDGKEKEHE---LHLDQSLEISNTLTNEKMKIEEYIKKGK---EDYEESHQRAVAA 1640
+ + ++E + + LD ++ + L ++ K ++ + + K Y + RA A
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484
Query: 1641 EVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKE 1700
+E E L + + EA K L + +ME + S + NV E
Sbjct: 1485 A-------REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV-HE 1536
Query: 1701 IEKAKSQFEEQIKAIKNGSRLSEL 1724
+EK+K E Q++ +K ++L EL
Sbjct: 1537 LEKSKRALETQMEEMK--TQLEEL 1558
Score = 45.8 bits (107), Expect = 4e-04
Identities = 49/239 (20%), Positives = 112/239 (46%), Gaps = 28/239 (11%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ 1550
+++R E+E Q +D+LQ+ E + K E ++LE+K + EE + + +L
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQ----KAENELKELEQKHSQLTEEKNLLQEQLQ---- 904
Query: 1551 DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISN 1610
E E+ E +E++ RL + K++++++ + EM + + +++ +L ++
Sbjct: 905 -AETEL---YAEAEEMRVRLAAKKQELEEILH--EMEARLEEEEDRGQQLQAER-----K 953
Query: 1611 TLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKL 1670
+ + + +EE +++ + ++ V AE + + E E+ +M+ Q K+
Sbjct: 954 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK--LEDEIL---VMDDQNNKLSKER 1008
Query: 1671 GLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEE-QIKAIKNGSRLSELSKVQ 1728
L+ D+ +++ E N+TK K +S E +++ K EL K++
Sbjct: 1009 KLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLK 1064
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/242 (21%), Positives = 102/242 (42%), Gaps = 23/242 (9%)
Query: 1496 EKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLER- 1554
E+E VL+ L E ++E + ++ E+L LE+ K +K LD Q LE+
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 1555 ------EIKKWQQEKKEIQERLKSLKKKIKKV-SNASEMYTQKNDGKEKEHEL--HLDQS 1605
E++ Q K+E++ + K L+ +++++ S S+ + + +K H+L ++
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Query: 1606 LEISNTLTNEKMKIEE---YIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ 1662
+ N + +K+ + + +D +E Q +++V ++ E + + +
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL 1359
Query: 1663 AEAFLKKLGL----------ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQI 1712
E K L +S D S + + E KEIE Q+EE+
Sbjct: 1360 DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 1419
Query: 1713 KA 1714
A
Sbjct: 1420 AA 1421
Score = 40.4 bits (93), Expect = 0.018
Identities = 61/268 (22%), Positives = 115/268 (42%), Gaps = 25/268 (9%)
Query: 1471 NIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQE---VYENYEQIKLKGLEETRDL 1527
N + QE++ + +RQ +S +EK+ + L E + Y + + E R+
Sbjct: 1430 NRLQQELDDLVVDLDNQRQ-LVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1488
Query: 1528 EEK---LKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNAS 1584
E K L R LEE +K EL+ + L+ E++ K ++ + + L+K K + +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK--SKRALET 1546
Query: 1585 EMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSV 1644
+M K +E E EL + + K+++E ++ K +E R + A
Sbjct: 1547 QMEEMKTQLEELEDELQATE---------DAKLRLEVNMQALKGQFE----RDLQARDEQ 1593
Query: 1645 LENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKA 1704
E + +L E++ E K+ L + AA +E D++ EL + K E+A
Sbjct: 1594 NEEKRRQLQRQLHEYETELEDERKQRALAA---AAKKKLEGDLKDLELQADSAIKGREEA 1650
Query: 1705 KSQFEEQIKAIKNGSRLSELSKVQISEL 1732
Q + +K+ R E ++ E+
Sbjct: 1651 IKQLRKLQAQMKDFQRELEDARASRDEI 1678
Score = 39.7 bits (91), Expect = 0.030
Identities = 55/246 (22%), Positives = 106/246 (43%), Gaps = 27/246 (10%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIK-----LKGLEETRDLEEKLKRHL-EENK 1539
EE Q ++R++ E + L+++ E I L R+ EK KR L EE +
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 1540 ISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHE 1599
KTEL+ L + Q+ + + ++ + LKK + + + + E Q+ K +
Sbjct: 1157 ALKTELEDTLDSTATQ----QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 1600 LHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIM 1659
L + LE + + + + K K+ E+ + +A E+ VL K+ +K + +
Sbjct: 1213 EELTEQLE-------QFKRAKANLDKNKQTLEKEN-ADLAGELRVLGQAKQEVEHKKKKL 1264
Query: 1660 ESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGS 1719
E+Q + K S A ++ + + + +VT + +A+ KAIK
Sbjct: 1265 EAQVQELQSK---CSDGERARAELNDKVHKLQNEVESVTGMLNEAEG------KAIKLAK 1315
Query: 1720 RLSELS 1725
++ LS
Sbjct: 1316 DVASLS 1321
Score = 35.4 bits (80), Expect = 0.57
Identities = 35/164 (21%), Positives = 71/164 (43%), Gaps = 1/164 (0%)
Query: 1489 QGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWF 1548
Q E R+E L+++L+E N E + + + T+ E+ L L + + + +
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ-LSNELATERSTAQKNESA 1793
Query: 1549 LQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEI 1608
Q LER+ K+ + + E++ +KS K A ++ +E + +SL+
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Query: 1609 SNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESE 1652
+ E + E +K E Y+E ++ A + +E+E
Sbjct: 1854 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1897
Score = 34.7 bits (78), Expect = 0.98
Identities = 42/246 (17%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 1491 EISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQ 1550
++ ++ + + L+D+LQ + ++++ E L+ E+N+ + +L L
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 1551 DLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISN 1610
+ E E+ + E+K Q L + KK K +G K+ EL D +++
Sbjct: 1607 EYETEL---EDERK--QRALAAAAKK-------------KLEGDLKDLELQADSAIKGRE 1648
Query: 1611 TLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQ-----AEA 1665
+ K++ +K + + E++ + EN K+++ + +M+ Q AE
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 1666 FLKKLGL--------ISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKN 1717
K+ L ++ + ++ + R E ++ + +E+E+ + E ++
Sbjct: 1709 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1768
Query: 1718 GSRLSE 1723
++ +E
Sbjct: 1769 ATQQAE 1774
Score = 32.3 bits (72), Expect = 4.8
Identities = 28/165 (16%), Positives = 74/165 (44%), Gaps = 8/165 (4%)
Query: 1486 EERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTEL 1545
E+ E++ Q + Q++ ++++ K E ++ K K + + +L
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 1546 DWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMY---TQKNDGKEKEHELHL 1602
+ ++ RE + + K+ ++LK + +++ +E Y +K + + K+ + L
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Query: 1603 DQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLEN 1647
+++ E S + + K++ + + E E A+ EV+ L++
Sbjct: 1894 EEAEEESQRINANRRKLQRELDEATESNE-----AMGREVNALKS 1933
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,215,927
Number of Sequences: 37866
Number of extensions: 4024552
Number of successful extensions: 30738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 264
Number of HSP's successfully gapped in prelim test: 1037
Number of HSP's that attempted gapping in prelim test: 22099
Number of HSP's gapped (non-prelim): 7885
length of query: 2025
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1908
effective length of database: 13,817,196
effective search space: 26363209968
effective search space used: 26363209968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.