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Search of human proteins with 48928044
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48928044 F-box only protein 8 [Homo sapiens]
(319 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48928044 F-box only protein 8 [Homo sapiens] 658 0.0
gi|53832026 IQ motif and Sec7 domain 2 isoform 2 [Homo sapiens] 107 1e-23
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 107 1e-23
gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens] 106 2e-23
gi|50582989 IQ motif and Sec7 domain 1 isoform b [Homo sapiens] 106 2e-23
gi|71143127 IQ motif and Sec7 domain 3 [Homo sapiens] 104 1e-22
gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange pr... 95 7e-20
gi|195972859 cytohesin 2 isoform 2 [Homo sapiens] 93 3e-19
gi|8670546 cytohesin 2 isoform 1 [Homo sapiens] 93 3e-19
gi|4758968 cytohesin 3 [Homo sapiens] 89 5e-18
gi|7019505 cytohesin 4 [Homo sapiens] 88 1e-17
gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange... 87 2e-17
gi|110349763 cytohesin 1 isoform 2 [Homo sapiens] 85 1e-16
gi|4758964 cytohesin 1 isoform 1 [Homo sapiens] 85 1e-16
gi|14150035 pleckstrin and Sec7 domain containing 2 [Homo sapiens] 57 2e-08
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti... 56 4e-08
gi|45827716 ADP-ribosylation factor guanine nucleotide factor 6 ... 54 2e-07
gi|117606360 ADP-ribosylation factor guanine nucleotide factor 6... 54 2e-07
gi|56788370 pleckstrin and Sec7 domain containing 4 [Homo sapiens] 53 4e-07
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 42 7e-04
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 42 7e-04
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 42 7e-04
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 41 0.002
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 41 0.002
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] 41 0.002
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 38 0.010
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 38 0.010
gi|67003566 F-box protein 48 [Homo sapiens] 37 0.023
gi|83035136 F-box protein 31 [Homo sapiens] 34 0.15
gi|219281831 F-box protein 15 isoform 2 [Homo sapiens] 34 0.15
>gi|48928044 F-box only protein 8 [Homo sapiens]
Length = 319
Score = 658 bits (1698), Expect = 0.0
Identities = 319/319 (100%), Positives = 319/319 (100%)
Query: 1 MGQGLWRVVRNQQLQQEGYSEQGYLTREQSRRMAASNISNTNHRKQVQGGIDIYHLLKAR 60
MGQGLWRVVRNQQLQQEGYSEQGYLTREQSRRMAASNISNTNHRKQVQGGIDIYHLLKAR
Sbjct: 1 MGQGLWRVVRNQQLQQEGYSEQGYLTREQSRRMAASNISNTNHRKQVQGGIDIYHLLKAR 60
Query: 61 KSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCVWQDLANDELLWQGLCKSTWGHCS 120
KSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCVWQDLANDELLWQGLCKSTWGHCS
Sbjct: 61 KSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCVWQDLANDELLWQGLCKSTWGHCS 120
Query: 121 IYNKNPPLGFSFRKLYMQLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTL 180
IYNKNPPLGFSFRKLYMQLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTL
Sbjct: 121 IYNKNPPLGFSFRKLYMQLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTL 180
Query: 181 NWKKLRIYLDERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSH 240
NWKKLRIYLDERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSH
Sbjct: 181 NWKKLRIYLDERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSH 240
Query: 241 RFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNIS 300
RFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNIS
Sbjct: 241 RFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNIS 300
Query: 301 EDFVGHLYDNIYLIGHVAA 319
EDFVGHLYDNIYLIGHVAA
Sbjct: 301 EDFVGHLYDNIYLIGHVAA 319
>gi|53832026 IQ motif and Sec7 domain 2 isoform 2 [Homo sapiens]
Length = 949
Score = 107 bits (267), Expect = 1e-23
Identities = 72/214 (33%), Positives = 116/214 (54%), Gaps = 17/214 (7%)
Query: 110 GLCKSTWGHCSIYNKNPPLGFSFRKLYMQLDE---GSLTFNANPDEGVNYFMSKGILDDS 166
GLCK T+ + ++ + P +F +Q G FN P++G+ Y + +G L D+
Sbjct: 523 GLCKQTYQRETRHSWDSP---AFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDT 579
Query: 167 PKEIAKFIFCTRTLNWKKLRIYLDER-----RDVLDDLVTLHNFRNQFLPNALREFFRHI 221
P +A FI + L+ + + +L R RDVLD +V +F + L +ALR+F HI
Sbjct: 580 PVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHI 639
Query: 222 HAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVK- 280
E + +E LI FS R+C CNP L+R+ +PD +++L +++ILL+ D+ SP VK
Sbjct: 640 RVQGE-AQKVERLIEAFSQRYCVCNPALVRQF-RNPDTIFILAFAIILLNTDMYSPSVKA 697
Query: 281 -NKMSKREFIRNTRRA--AQNISEDFVGHLYDNI 311
KM +FI+N R ++I D + +Y I
Sbjct: 698 ERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRI 731
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 107 bits (267), Expect = 1e-23
Identities = 72/214 (33%), Positives = 116/214 (54%), Gaps = 17/214 (7%)
Query: 110 GLCKSTWGHCSIYNKNPPLGFSFRKLYMQLDE---GSLTFNANPDEGVNYFMSKGILDDS 166
GLCK T+ + ++ + P +F +Q G FN P++G+ Y + +G L D+
Sbjct: 728 GLCKQTYQRETRHSWDSP---AFNNDVVQRRHYRIGLNLFNKKPEKGIQYLIERGFLSDT 784
Query: 167 PKEIAKFIFCTRTLNWKKLRIYLDER-----RDVLDDLVTLHNFRNQFLPNALREFFRHI 221
P +A FI + L+ + + +L R RDVLD +V +F + L +ALR+F HI
Sbjct: 785 PVGVAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHI 844
Query: 222 HAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAVYVLCYSLILLSIDLTSPHVK- 280
E + +E LI FS R+C CNP L+R+ +PD +++L +++ILL+ D+ SP VK
Sbjct: 845 RVQGE-AQKVERLIEAFSQRYCVCNPALVRQF-RNPDTIFILAFAIILLNTDMYSPSVKA 902
Query: 281 -NKMSKREFIRNTRRA--AQNISEDFVGHLYDNI 311
KM +FI+N R ++I D + +Y I
Sbjct: 903 ERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRI 936
>gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens]
Length = 1114
Score = 106 bits (265), Expect = 2e-23
Identities = 74/229 (32%), Positives = 121/229 (52%), Gaps = 17/229 (7%)
Query: 95 SCVWQDLANDELLWQGLCKSTWGHCSIYNKNPPLGFS---FRKLYMQLDEGSLTFNANPD 151
+C + + D L Q L K T+ H N FS RK + ++ G FN P+
Sbjct: 470 NCSSESSSRDSLREQTLSKQTY-HKEARNSWDSPAFSNDVIRKRHYRI--GLNLFNKKPE 526
Query: 152 EGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDER-----RDVLDDLVTLHNFR 206
+GV Y + +G + D+P +A F+ + L+ + + +L R RDVLD +V +F
Sbjct: 527 KGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFS 586
Query: 207 NQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAVYVLCYS 266
L ALR+F HI E + +E LI FS R+C CNP ++R+ +PD +++L ++
Sbjct: 587 TMELDEALRKFQAHIRVQGE-AQKVERLIEAFSQRYCICNPGVVRQF-RNPDTIFILAFA 644
Query: 267 LILLSIDLTSPHVK--NKMSKREFIRNTRRA--AQNISEDFVGHLYDNI 311
+ILL+ D+ SP+VK KM +FI+N R ++I + + +Y+ I
Sbjct: 645 IILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERI 693
>gi|50582989 IQ motif and Sec7 domain 1 isoform b [Homo sapiens]
Length = 963
Score = 106 bits (265), Expect = 2e-23
Identities = 74/229 (32%), Positives = 121/229 (52%), Gaps = 17/229 (7%)
Query: 95 SCVWQDLANDELLWQGLCKSTWGHCSIYNKNPPLGFS---FRKLYMQLDEGSLTFNANPD 151
+C + + D L Q L K T+ H N FS RK + ++ G FN P+
Sbjct: 484 NCSSESSSRDSLREQTLSKQTY-HKEARNSWDSPAFSNDVIRKRHYRI--GLNLFNKKPE 540
Query: 152 EGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDER-----RDVLDDLVTLHNFR 206
+GV Y + +G + D+P +A F+ + L+ + + +L R RDVLD +V +F
Sbjct: 541 KGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFS 600
Query: 207 NQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAVYVLCYS 266
L ALR+F HI E + +E LI FS R+C CNP ++R+ +PD +++L ++
Sbjct: 601 TMELDEALRKFQAHIRVQGE-AQKVERLIEAFSQRYCICNPGVVRQF-RNPDTIFILAFA 658
Query: 267 LILLSIDLTSPHVK--NKMSKREFIRNTRRA--AQNISEDFVGHLYDNI 311
+ILL+ D+ SP+VK KM +FI+N R ++I + + +Y+ I
Sbjct: 659 IILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERI 707
>gi|71143127 IQ motif and Sec7 domain 3 [Homo sapiens]
Length = 759
Score = 104 bits (259), Expect = 1e-22
Identities = 60/175 (34%), Positives = 102/175 (58%), Gaps = 11/175 (6%)
Query: 146 FNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDE-----RRDVLDDLV 200
FN NPD+G+ + +S+G + D+P +A F+ + L+ + + +L RDVLD +V
Sbjct: 359 FNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVV 418
Query: 201 TLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAV 260
+F + L ALR+F HI E + +E LI FS R+C CNP+++++ +PD +
Sbjct: 419 DEMDFSSMELDEALRKFQAHIRVQGE-AQKVERLIEAFSQRYCMCNPEVVQQFH-NPDTI 476
Query: 261 YVLCYSLILLSIDLTSPHVK--NKMSKREFIRNTRRA--AQNISEDFVGHLYDNI 311
++L +++ILL+ D+ SP++K KM +FIRN R +I + V +Y+ I
Sbjct: 477 FILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERI 531
>gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange
protein 1 [Homo sapiens]
Length = 1849
Score = 95.1 bits (235), Expect = 7e-20
Identities = 55/179 (30%), Positives = 100/179 (55%), Gaps = 9/179 (5%)
Query: 139 LDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDER----RD 194
+++G FN P G+ Y +G+L +P++IA+F+ L+ ++ +L + ++
Sbjct: 702 IEQGIDLFNKKPKRGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKE 761
Query: 195 VLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELG 254
V+ V H+F + +ALR F P E + ++ L+ KF+ R+ CN + L
Sbjct: 762 VMYAYVDQHDFSGKDFVSALRMFLEGFRLPGE-AQKIDRLMEKFAARYLECNQG--QTLF 818
Query: 255 LSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
S D YVL YS+I+L+ DL SP VKNKM+K ++I+ R ++++ E+++ +Y+ I
Sbjct: 819 ASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEI 877
>gi|195972859 cytohesin 2 isoform 2 [Homo sapiens]
Length = 399
Score = 93.2 bits (230), Expect = 3e-19
Identities = 54/176 (30%), Positives = 95/176 (53%), Gaps = 11/176 (6%)
Query: 142 GSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRD----VLD 197
G FN +P +G+ + + +L ++P+EIA+F++ LN + YL ER + VL
Sbjct: 68 GRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLH 127
Query: 198 DLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSP 257
V LH F + L ALR+F P E + ++ ++ F+ R+C CNP + + S
Sbjct: 128 AFVDLHEFTDLNLVQALRQFLWSFRLPGE-AQKIDRMMEAFAQRYCLCNPGVFQ----ST 182
Query: 258 DAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
D YVL +++I+L+ L +P+V++K F+ R ++ E+ + +LYD+I
Sbjct: 183 DTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSI 238
>gi|8670546 cytohesin 2 isoform 1 [Homo sapiens]
Length = 400
Score = 93.2 bits (230), Expect = 3e-19
Identities = 54/176 (30%), Positives = 95/176 (53%), Gaps = 11/176 (6%)
Query: 142 GSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRD----VLD 197
G FN +P +G+ + + +L ++P+EIA+F++ LN + YL ER + VL
Sbjct: 68 GRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLH 127
Query: 198 DLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSP 257
V LH F + L ALR+F P E + ++ ++ F+ R+C CNP + + S
Sbjct: 128 AFVDLHEFTDLNLVQALRQFLWSFRLPGE-AQKIDRMMEAFAQRYCLCNPGVFQ----ST 182
Query: 258 DAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
D YVL +++I+L+ L +P+V++K F+ R ++ E+ + +LYD+I
Sbjct: 183 DTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSI 238
>gi|4758968 cytohesin 3 [Homo sapiens]
Length = 399
Score = 89.0 bits (219), Expect = 5e-18
Identities = 53/180 (29%), Positives = 96/180 (53%), Gaps = 11/180 (6%)
Query: 138 QLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRD--- 194
Q+ G FN +P +G+ + + +L SP+++A+F++ LN + YL ER +
Sbjct: 69 QIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNI 128
Query: 195 -VLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMREL 253
VL V LH F + L ALR+F P E + ++ ++ F+ R+C CNP + +
Sbjct: 129 KVLQAFVELHEFADLNLVQALRQFLWSFRLPGE-AQKIDRMMEAFASRYCLCNPGVFQ-- 185
Query: 254 GLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
S D YVL +++I+L+ L + +V++K + FI R ++ E+ + +LY++I
Sbjct: 186 --STDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLYESI 243
>gi|7019505 cytohesin 4 [Homo sapiens]
Length = 394
Score = 87.8 bits (216), Expect = 1e-17
Identities = 54/176 (30%), Positives = 91/176 (51%), Gaps = 11/176 (6%)
Query: 142 GSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDER----RDVLD 197
G FN +P +G+ YF+ +L ++IA+F++ LN + YL ER VL
Sbjct: 68 GRKKFNMDPAKGIQYFIEHKLLTPDVQDIARFLYKGEGLNKTAIGTYLGERDPINLQVLQ 127
Query: 198 DLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSP 257
V H F N L ALR+F P E + ++ ++ F+ R+C CNP + + S
Sbjct: 128 AFVDCHEFANLNLVQALRQFLWSFRLPGE-AQKIDRMMEAFATRYCLCNPGVFQ----ST 182
Query: 258 DAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
D YVL +S+I+L+ L +P+V+++ F+ R ++ ED + +L+D+I
Sbjct: 183 DTCYVLSFSIIMLNTSLHNPNVRDRPPFERFVSMNRGINNGSDLPEDQLRNLFDSI 238
>gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange
factor 2 [Homo sapiens]
Length = 1785
Score = 87.0 bits (214), Expect = 2e-17
Identities = 53/179 (29%), Positives = 97/179 (54%), Gaps = 9/179 (5%)
Query: 139 LDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDE----RRD 194
++ G FN P G+ + +G+L S ++IA+F+ L+ ++ +L + ++
Sbjct: 647 IEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKE 706
Query: 195 VLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELG 254
V+ V +F + +ALR F P E + ++ L+ KF+ R+ CN + L
Sbjct: 707 VMYAYVDQLDFCEKEFVSALRTFLEGFRLPGE-AQKIDRLMEKFAARYIECNQG--QTLF 763
Query: 255 LSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
S D YVL YS+I+L+ DL SP VKNKM+K ++I+ R ++++ E+++ +Y+ I
Sbjct: 764 ASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEI 822
>gi|110349763 cytohesin 1 isoform 2 [Homo sapiens]
Length = 397
Score = 84.7 bits (208), Expect = 1e-16
Identities = 53/180 (29%), Positives = 96/180 (53%), Gaps = 11/180 (6%)
Query: 138 QLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRD--- 194
Q+ G FN +P +G+ + + +L ++ ++IA+F++ LN + YL ER +
Sbjct: 65 QVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNI 124
Query: 195 -VLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMREL 253
VL V LH F + L ALR+F P E + ++ ++ F+ R+C CN + +
Sbjct: 125 QVLHAFVELHEFTDLNLVQALRQFLWSFRLPGE-AQKIDRMMEAFAQRYCQCNNGVFQ-- 181
Query: 254 GLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
S D YVL +++I+L+ L +P+VK+K + FI R ++ E+ + +LY++I
Sbjct: 182 --STDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESI 239
>gi|4758964 cytohesin 1 isoform 1 [Homo sapiens]
Length = 398
Score = 84.7 bits (208), Expect = 1e-16
Identities = 53/180 (29%), Positives = 96/180 (53%), Gaps = 11/180 (6%)
Query: 138 QLDEGSLTFNANPDEGVNYFMSKGILDDSPKEIAKFIFCTRTLNWKKLRIYLDERRD--- 194
Q+ G FN +P +G+ + + +L ++ ++IA+F++ LN + YL ER +
Sbjct: 65 QVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNI 124
Query: 195 -VLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMREL 253
VL V LH F + L ALR+F P E + ++ ++ F+ R+C CN + +
Sbjct: 125 QVLHAFVELHEFTDLNLVQALRQFLWSFRLPGE-AQKIDRMMEAFAQRYCQCNNGVFQ-- 181
Query: 254 GLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHLYDNI 311
S D YVL +++I+L+ L +P+VK+K + FI R ++ E+ + +LY++I
Sbjct: 182 --STDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESI 239
>gi|14150035 pleckstrin and Sec7 domain containing 2 [Homo sapiens]
Length = 771
Score = 57.4 bits (137), Expect = 2e-08
Identities = 39/121 (32%), Positives = 63/121 (52%), Gaps = 7/121 (5%)
Query: 193 RDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRE 252
R V + ++ +F L ALR F + E E E ++T FS R+C CNPD
Sbjct: 344 RLVAGEYLSFFDFSGLTLDGALRTFLKAFPLMGETQER-ERVLTHFSRRYCQCNPDD--- 399
Query: 253 LGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRA--AQNISEDFVGHLYDN 310
S D ++ L +L+LL+ DL ++ KMS ++FI N + Q+ ++D + LY++
Sbjct: 400 -STSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNS 458
Query: 311 I 311
I
Sbjct: 459 I 459
>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
exchange factor 1 [Homo sapiens]
Length = 1859
Score = 56.2 bits (134), Expect = 4e-08
Identities = 44/178 (24%), Positives = 88/178 (49%), Gaps = 14/178 (7%)
Query: 142 GSLTFNANPDEGVNYFMSKGIL--DDSPKEIAKFIFCTRTLNWKKLRIYLDERR--DVLD 197
G+ FN P +G+ + KG+L E+A+++ L+ K + ++ +R+ D+L+
Sbjct: 706 GTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLE 765
Query: 198 DLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSP 257
V+ +F+ L ALR + P E ++ L+ F+ R+ CN +
Sbjct: 766 SFVSTFSFQGLRLDEALRLYLEAFRLPGE-APVIQRLLEAFTERWMNCNGSPF----ANS 820
Query: 258 DAVYVLCYSLILLSIDLTSPHVKNK---MSKREFIRNTRRAAQNISEDFVGHLYDNIY 312
DA + L Y++I+L+ D + +V+ + M+ EF +N + N +DF + +++Y
Sbjct: 821 DACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLK--GVNGGKDFEQDILEDMY 876
>gi|45827716 ADP-ribosylation factor guanine nucleotide factor 6
isoform b [Homo sapiens]
Length = 513
Score = 53.9 bits (128), Expect = 2e-07
Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 7/119 (5%)
Query: 195 VLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELG 254
V ++ + +F L +LR FF+ E E E ++ FS+R+ CNPD +
Sbjct: 83 VAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQER-ERVLIHFSNRYFYCNPDTIA--- 138
Query: 255 LSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNI--SEDFVGHLYDNI 311
S D V+ L +++LL+ DL ++ KM+ +EFI N + + + S+D + LY++I
Sbjct: 139 -SQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSI 196
>gi|117606360 ADP-ribosylation factor guanine nucleotide factor 6
isoform a [Homo sapiens]
Length = 1047
Score = 53.9 bits (128), Expect = 2e-07
Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 7/119 (5%)
Query: 195 VLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELG 254
V ++ + +F L +LR FF+ E E E ++ FS+R+ CNPD +
Sbjct: 617 VAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQER-ERVLIHFSNRYFYCNPDTIA--- 672
Query: 255 LSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTRRAAQNI--SEDFVGHLYDNI 311
S D V+ L +++LL+ DL ++ KM+ +EFI N + + + S+D + LY++I
Sbjct: 673 -SQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSI 730
>gi|56788370 pleckstrin and Sec7 domain containing 4 [Homo sapiens]
Length = 1056
Score = 52.8 bits (125), Expect = 4e-07
Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 7/124 (5%)
Query: 190 DERRDVLDDLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDL 249
D R V ++ ++ F Q L ALR F + + E E E ++ +FS RF CNP +
Sbjct: 615 DFSRAVAEEYLSFFQFGGQSLDRALRSFLQALVLSGETQER-ERILYQFSRRFHHCNPGI 673
Query: 250 MRELGLSPDAVYVLCYSLILLSIDLTSPHVKNKMSKREFIRNTR--RAAQNISEDFVGHL 307
S D+V+ L +++LL+ DL ++ MS +EFI N R N ++ + L
Sbjct: 674 FP----SVDSVHTLTCAIMLLNTDLHGQNIGKSMSCQEFITNLNGLRDGGNFPKELLKAL 729
Query: 308 YDNI 311
Y +I
Sbjct: 730 YWSI 733
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 42.0 bits (97), Expect = 7e-04
Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 5/64 (7%)
Query: 53 IYHLLKARKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQ 109
+ H+++ + + Q FI+L LP EL+ +LS+L DL A+ W+ LA D LLW+
Sbjct: 147 VKHMMQVIEPQFQRDFISL--LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 204
Query: 110 GLCK 113
CK
Sbjct: 205 EKCK 208
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 42.0 bits (97), Expect = 7e-04
Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 5/64 (7%)
Query: 53 IYHLLKARKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQ 109
+ H+++ + + Q FI+L LP EL+ +LS+L DL A+ W+ LA D LLW+
Sbjct: 265 VKHMMQVIEPQFQRDFISL--LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 322
Query: 110 GLCK 113
CK
Sbjct: 323 EKCK 326
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 42.0 bits (97), Expect = 7e-04
Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 5/64 (7%)
Query: 53 IYHLLKARKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQ 109
+ H+++ + + Q FI+L LP EL+ +LS+L DL A+ W+ LA D LLW+
Sbjct: 185 VKHMMQVIEPQFQRDFISL--LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 242
Query: 110 GLCK 113
CK
Sbjct: 243 EKCK 246
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/43 (48%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Query: 72 EMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGL 111
E LP E+ I SYL DLC A+CV + +LAND +LW+ L
Sbjct: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRL 115
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/43 (48%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Query: 72 EMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGL 111
E LP E+ I SYL DLC A+CV + +LAND +LW+ L
Sbjct: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRL 115
>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
Length = 585
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/43 (48%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Query: 72 EMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGL 111
E LP E+ I SYL DLC A+CV + +LAND +LW+ L
Sbjct: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRL 115
>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
sapiens]
Length = 565
Score = 38.1 bits (87), Expect = 0.010
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Query: 60 RKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGLCKSTW 116
++++ E + LPPE+ +I SYLN +LC S V W L LW+ L W
Sbjct: 68 KEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW 127
Query: 117 GHCSIYN 123
Y+
Sbjct: 128 ARGDWYS 134
>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
sapiens]
Length = 691
Score = 38.1 bits (87), Expect = 0.010
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Query: 60 RKSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGLCKSTW 116
++++ E + LPPE+ +I SYLN +LC S V W L LW+ L W
Sbjct: 194 KEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW 253
Query: 117 GHCSIYN 123
Y+
Sbjct: 254 ARGDWYS 260
>gi|67003566 F-box protein 48 [Homo sapiens]
Length = 155
Score = 37.0 bits (84), Expect = 0.023
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 6/63 (9%)
Query: 61 KSKEQEGFINLEMLPPELSFTILSYLNATDLCLASCV---WQD-LANDELLWQGLCKSTW 116
K++ Q F E+LP E++F I S L+ LC AS W D + N + LW+ C +
Sbjct: 27 KNESQNNFF--ELLPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSLWKPHCMTVR 84
Query: 117 GHC 119
C
Sbjct: 85 AVC 87
>gi|83035136 F-box protein 31 [Homo sapiens]
Length = 539
Score = 34.3 bits (77), Expect = 0.15
Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 74 LPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGLCKSTWGHCSIYNKNPPLGF 130
LPPEL I + L TDL + V ++ + + + +W+ C+ +G C K G
Sbjct: 70 LPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCREEYGVCENLRKLEITGV 129
Query: 131 SFRKLYMQL 139
S R +Y +L
Sbjct: 130 SCRDVYAKL 138
>gi|219281831 F-box protein 15 isoform 2 [Homo sapiens]
Length = 510
Score = 34.3 bits (77), Expect = 0.15
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
Query: 71 LEMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGL 111
L+ +P E+ I SYL+A L CV + LAND +W G+
Sbjct: 74 LDGMPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIWIGI 117
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,292,616
Number of Sequences: 37866
Number of extensions: 535982
Number of successful extensions: 1184
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1112
Number of HSP's gapped (non-prelim): 54
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.