Guide to the Human Genome
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Name: DMPK Sequence: fasta or formatted (625aa) NCBI GI: 126091040
Description:

myotonic dystrophy protein kinase isoform 4

Referenced in:

Muscle
Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt prot [639aa] myotonic dystrophy protein kinase isoform 1
alt prot [624aa] myotonic dystrophy protein kinase isoform 3
alt prot [629aa] myotonic dystrophy protein kinase isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.6         60           2
 C cysteine            2.1         13           2
 D aspartate           5.8         36           2
 E glutamate           8.8         55           3
 F phenylalanine       4.0         25           3
 G glycine             7.4         46           3
 H histidine           1.9         12           1
 I isoleucine          2.6         16           1
 K lysine              2.1         13           1
 L leucine            11.7         73           3
 M methionine          2.4         15           1
 N asparagine          1.4          9           1
 P proline             7.8         49           3
 Q glutamine           4.2         26           2
 R arginine            6.9         43           3
 S serine              5.1         32           1
 T threonine           4.3         27           1
 V valine              7.0         44           2
 W tryptophan          2.1         13           2
 Y tyrosine            2.9         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   myotonic dystrophy protein kinase isoform 4 
DMPK                  0.853   myotonic dystrophy protein kinase isoform 3 
DMPK                  0.848   myotonic dystrophy protein kinase isoform 2 
DMPK                  0.767   myotonic dystrophy protein kinase isoform 1 
CDC42BPA              0.395   CDC42-binding protein kinase alpha isoform B 
CDC42BPA              0.395   CDC42-binding protein kinase alpha isoform A 
CDC42BPB              0.390   CDC42-binding protein kinase beta 
CDC42BPG              0.389   CDC42 binding protein kinase gamma (DMPK-like) [Hom...
ROCK1                 0.271   Rho-associated, coiled-coil containing protein kinase...
ROCK2                 0.271   Rho-associated, coiled-coil containing protein kinas...
CIT                   0.247   citron 
STK38L                0.199   serine/threonine kinase 38 like 
STK38                 0.198   serine/threonine kinase 38 
MAST3                 0.153   microtubule associated serine/threonine kinase 3 [H...
MAST2                 0.151   microtubule associated serine/threonine kinase 2 [H...
MAST1                 0.150   microtubule associated serine/threonine kinase 1 [Ho...
MAST4                 0.148   microtubule associated serine/threonine kinase fami...
PRKCH                 0.139   protein kinase C, eta 
RPS6KA6               0.137   ribosomal protein S6 kinase polypeptide 6 
PRKACA                0.137   cAMP-dependent protein kinase catalytic subunit alpha...
PRKACG                0.137   protein kinase, cAMP-dependent, catalytic, gamma [Ho...
PRKCE                 0.136   protein kinase C, epsilon 
PRKACA                0.136   cAMP-dependent protein kinase catalytic subunit alph...
PRKACB                0.136   cAMP-dependent protein kinase catalytic subunit beta...
PRKACB                0.135   cAMP-dependent protein kinase catalytic subunit beta ...
RPS6KA2               0.131   ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...
RPS6KA2               0.131   ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...
PRKCQ                 0.130   protein kinase C, theta 
RPS6KA1               0.129   ribosomal protein S6 kinase, 90kDa, polypeptide 1 is...
RPS6KA1               0.129   ribosomal protein S6 kinase, 90kDa, polypeptide 1 is...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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