Guide to the Human Genome
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Name: PRKACA Sequence: fasta or formatted (351aa) NCBI GI: 4506055
Description:

cAMP-dependent protein kinase catalytic subunit alpha isoform 1

Referenced in:

Cyclic Nucleotides

Other entries for this name:
alt prot [343aa] cAMP-dependent protein kinase catalytic subunit alpha isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         23           4
 C cysteine            0.6          2           1
 D aspartate           5.1         18           2
 E glutamate           7.7         27           4
 F phenylalanine       7.1         25           2
 G glycine             6.3         22           2
 H histidine           2.6          9           1
 I isoleucine          6.0         21           2
 K lysine             10.0         35           2
 L leucine             9.1         32           2
 M methionine          2.0          7           1
 N asparagine          4.6         16           1
 P proline             4.0         14           2
 Q glutamine           4.0         14           2
 R arginine            4.3         15           2
 S serine              4.8         17           2
 T threonine           4.0         14           2
 V valine              5.7         20           2
 W tryptophan          1.7          6           2
 Y tyrosine            4.0         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cAMP-dependent protein kinase catalytic subunit alpha... 
PRKACA                0.962   cAMP-dependent protein kinase catalytic subunit alph...
PRKACB                0.928   cAMP-dependent protein kinase catalytic subunit beta ...
PRKACB                0.895   cAMP-dependent protein kinase catalytic subunit beta...
PRKACG                0.848   protein kinase, cAMP-dependent, catalytic, gamma [Ho...
PRKACB                0.663   cAMP-dependent protein kinase catalytic subunit beta...
PRKX                  0.500   protein kinase, X-linked 
PRKG2                 0.371   protein kinase, cGMP-dependent, type II 
PRKG1                 0.366   protein kinase, cGMP-dependent, type I isoform 1 [H...
PRKG1                 0.366   protein kinase, cGMP-dependent, type I isoform 2 [Ho...
AKT3                  0.351   AKT3 kinase isoform 2 
SGK2                  0.351   serum/glucocorticoid regulated kinase 2 isoform alph...
SGK2                  0.351   serum/glucocorticoid regulated kinase 2 isoform beta...
SGK1                  0.350   serum/glucocorticoid regulated kinase 1 isoform 1 [H...
SGK1                  0.350   serum/glucocorticoid regulated kinase 1 isoform 4 [...
SGK1                  0.350   serum/glucocorticoid regulated kinase 1 isoform 3 [...
SGK1                  0.350   serum/glucocorticoid regulated kinase 1 isoform 2 [...
AKT2                  0.348   AKT2 kinase 
AKT3                  0.347   AKT3 kinase isoform 1 
AKT1                  0.345   AKT1 kinase 
AKT1                  0.345   AKT1 kinase 
AKT1                  0.345   AKT1 kinase 
PKN2                  0.327   protein kinase N2 
SGK3                  0.325   serum/glucocorticoid regulated kinase 3 isoform 1 [H...
SGK3                  0.325   serum/glucocorticoid regulated kinase 3 isoform 1 [H...
PRKCH                 0.324   protein kinase C, eta 
PRKCE                 0.312   protein kinase C, epsilon 
PRKCB                 0.312   protein kinase C, beta isoform 1 
RPS6KA4               0.309   ribosomal protein S6 kinase, 90kDa, polypeptide 4 is...
RPS6KA4               0.309   ribosomal protein S6 kinase, 90kDa, polypeptide 4 iso...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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