BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4885261 growth differentiation factor 9 precursor [Homo sapiens] (454 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4885261 growth differentiation factor 9 precursor [Homo sapiens] 937 0.0 gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens] 164 1e-40 gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi... 88 2e-17 gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi... 86 7e-17 gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa... 85 1e-16 gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa... 85 1e-16 gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa... 85 1e-16 gi|61835232 growth differentiation factor 7 preproprotein [Homo ... 84 3e-16 gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens] 84 3e-16 gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sap... 84 3e-16 gi|48475062 growth differentiation factor 6 precursor [Homo sapi... 83 4e-16 gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa... 82 1e-15 gi|4503969 growth differentiation factor 5 preproprotein [Homo s... 80 4e-15 gi|222352098 nodal precursor [Homo sapiens] 78 1e-14 gi|10190670 growth differentiation factor 3 precursor [Homo sapi... 78 1e-14 gi|110349792 growth differentiation factor 1 [Homo sapiens] 78 2e-14 gi|7705308 growth differentiation factor 2 [Homo sapiens] 77 4e-14 gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap... 75 9e-14 gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sa... 75 2e-13 gi|145611428 bone morphogenetic protein 8A [Homo sapiens] 74 4e-13 gi|153792495 growth differentiation factor 15 [Homo sapiens] 69 7e-12 gi|239757187 PREDICTED: similar to growth differentiation factor... 69 7e-12 gi|4504699 inhibin beta A precursor [Homo sapiens] 68 1e-11 gi|13899338 activin beta E [Homo sapiens] 65 2e-10 gi|4826740 growth differentiation factor 10 precursor [Homo sapi... 63 5e-10 gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens] 61 2e-09 gi|5031795 inhibin beta C chain preproprotein [Homo sapiens] 58 2e-08 gi|4885259 myostatin [Homo sapiens] 57 3e-08 gi|5031613 growth differentiation factor 11 precursor [Homo sapi... 57 5e-08 gi|4504697 inhibin alpha subunit precursor [Homo sapiens] 46 8e-05 >gi|4885261 growth differentiation factor 9 precursor [Homo sapiens] Length = 454 Score = 937 bits (2423), Expect = 0.0 Identities = 454/454 (100%), Positives = 454/454 (100%) Query: 1 MARPNKFLLWFCCFAWLCFPISLGSQASGGEAQIAASAELESGAMPWSLLQHIDERDRAG 60 MARPNKFLLWFCCFAWLCFPISLGSQASGGEAQIAASAELESGAMPWSLLQHIDERDRAG Sbjct: 1 MARPNKFLLWFCCFAWLCFPISLGSQASGGEAQIAASAELESGAMPWSLLQHIDERDRAG 60 Query: 61 LLPALFKVLSVGRGGSPRLQPDSRALHYMKKLYKTYATKEGIPKSNRSHLYNTVRLFTPC 120 LLPALFKVLSVGRGGSPRLQPDSRALHYMKKLYKTYATKEGIPKSNRSHLYNTVRLFTPC Sbjct: 61 LLPALFKVLSVGRGGSPRLQPDSRALHYMKKLYKTYATKEGIPKSNRSHLYNTVRLFTPC 120 Query: 121 TRHKQAPGDQVTGILPSVELLFNLDRITTVEHLLKSVLLYNINNSVSFSSAVKCVCNLMI 180 TRHKQAPGDQVTGILPSVELLFNLDRITTVEHLLKSVLLYNINNSVSFSSAVKCVCNLMI Sbjct: 121 TRHKQAPGDQVTGILPSVELLFNLDRITTVEHLLKSVLLYNINNSVSFSSAVKCVCNLMI 180 Query: 181 KEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTCM 240 KEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTCM Sbjct: 181 KEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTCM 240 Query: 241 KDQLEHPSAQNGLFNMTLVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLSAY 300 KDQLEHPSAQNGLFNMTLVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLSAY Sbjct: 241 KDQLEHPSAQNGLFNMTLVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLSAY 300 Query: 301 PVGEEAAEDGRSSHHRHRRGQETVSSELKKPLGPASFNLSEYFRQFLLPQNECELHDFRL 360 PVGEEAAEDGRSSHHRHRRGQETVSSELKKPLGPASFNLSEYFRQFLLPQNECELHDFRL Sbjct: 301 PVGEEAAEDGRSSHHRHRRGQETVSSELKKPLGPASFNLSEYFRQFLLPQNECELHDFRL 360 Query: 361 SFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPRPSCV 420 SFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPRPSCV Sbjct: 361 SFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPRPSCV 420 Query: 421 PAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 PAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR Sbjct: 421 PAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 >gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens] Length = 392 Score = 164 bits (416), Expect = 1e-40 Identities = 138/439 (31%), Positives = 190/439 (43%), Gaps = 83/439 (18%) Query: 27 ASGGEAQIAASAELESGAMPWSLLQHIDERDRAGLLPALFKVLSVGRGGSPRLQPD--SR 84 A GG++ IA AE A LP + ++L G PR +P Sbjct: 26 AEGGQSSIALLAE-------------------APTLPLIEELLEESPGEQPR-KPRLLGH 65 Query: 85 ALHYMKKLYKTYATKEGIPKSNRSHLYNTVRLFTPCTR----HKQAPGDQVTGI-LPSVE 139 +L YM +LY+ A G P+ NR+ VRL P T H+ Q+ G L Sbjct: 66 SLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTSVARPHRGTWHIQILGFPLRPNR 125 Query: 140 LLFNLDRITTVEHLLKSVLLYNINNSVSFSSAVKCVCNLMIKEPKSSSRTLGRAPYSFTF 199 L+ L R T V + +N++ V EP P S Sbjct: 126 GLYQLVRATVVYRHHLQLTRFNLSCHV---------------EPWVQKNPTNHFPSSEGD 170 Query: 200 NSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTCMKDQLEHPSAQNGLFNMTLV 259 +S+ + W ++D+T L+Q +NK + + F C + Q + + +L Sbjct: 171 SSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQ-QKDSGGLELWHGTSSLD 228 Query: 260 SPSLILYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLSAYPVGEEAAEDGRSSHHRHRR 319 L+LY NDT R P G E + R S R R Sbjct: 229 IAFLLLYFNDTHKSI--------------------RKAKFLPRGMEEFME-RESLLRRTR 267 Query: 320 GQETVSSEL----KKPLGPASFNLSEYFRQFLLPQNECELHDFRLSFSQLKWDNWIVAPH 375 + +S+E+ K GP + N+C LH F++SF QL WD+WI+AP Sbjct: 268 QADGISAEVTASSSKHSGPEN--------------NQCSLHPFQISFRQLGWDHWIIAPP 313 Query: 376 RYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPRPSCVPAKYSPLSVLTIEPD 435 Y P YCKG C R + SP H ++QN+I + +D SVPRPSCVP KY P+SVL IE + Sbjct: 314 FYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEAN 373 Query: 436 GSIAYKEYEDMIATKCTCR 454 GSI YKEYE MIA CTCR Sbjct: 374 GSILYKEYEGMIAESCTCR 392 >gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapiens] Length = 513 Score = 87.8 bits (216), Expect = 2e-17 Identities = 44/157 (28%), Positives = 74/157 (47%), Gaps = 10/157 (6%) Query: 300 YPVGEEAAEDGRSSHHRHR---RGQETVSSELKKPLGPASFNLSEYFRQFLLPQNECELH 356 + V E RS+ R R R + T S ++ + + +N SE + C H Sbjct: 363 FKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVARVSSASDYNSSEL-------KTACRKH 415 Query: 357 DFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPR 416 + +SF L W +WI+AP Y YC G+C + + H +VQ +++ VP+ Sbjct: 416 ELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPK 475 Query: 417 PSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 P C P K + +SVL + + ++ K+Y +M+ C C Sbjct: 476 PCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 512 >gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapiens] Length = 396 Score = 85.9 bits (211), Expect = 7e-17 Identities = 35/105 (33%), Positives = 61/105 (58%), Gaps = 1/105 (0%) Query: 350 QNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK 409 ++ C+ H + FS + W++WIVAP Y+ YC G+CP + S H +VQ ++ Sbjct: 293 KSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLV-NS 351 Query: 410 LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 ++S +P+ CVP + S +S+L ++ + + K Y+DM+ C CR Sbjct: 352 VNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR 396 >gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sapiens] Length = 408 Score = 85.1 bits (209), Expect = 1e-16 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 1/102 (0%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDS 412 C H + FS + W++WIVAP Y YC GDCP + S H +VQ ++ ++S Sbjct: 308 CRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLV-NSVNS 366 Query: 413 SVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 S+P+ CVP + S +S+L ++ + K Y++M+ C CR Sbjct: 367 SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 408 >gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sapiens] Length = 408 Score = 85.1 bits (209), Expect = 1e-16 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 1/102 (0%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDS 412 C H + FS + W++WIVAP Y YC GDCP + S H +VQ ++ ++S Sbjct: 308 CRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLV-NSVNS 366 Query: 413 SVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 S+P+ CVP + S +S+L ++ + K Y++M+ C CR Sbjct: 367 SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 408 >gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sapiens] Length = 408 Score = 85.1 bits (209), Expect = 1e-16 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 1/102 (0%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDS 412 C H + FS + W++WIVAP Y YC GDCP + S H +VQ ++ ++S Sbjct: 308 CRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLV-NSVNS 366 Query: 413 SVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 S+P+ CVP + S +S+L ++ + K Y++M+ C CR Sbjct: 367 SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 408 >gi|61835232 growth differentiation factor 7 preproprotein [Homo sapiens] Length = 450 Score = 84.0 bits (206), Expect = 3e-16 Identities = 34/105 (32%), Positives = 56/105 (53%) Query: 350 QNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK 409 ++ C + F +L WD+WI+AP Y +C+G C + H ++Q ++ Sbjct: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405 Query: 410 LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 + P CVPA+ SP+S+L I+ ++ YK+YEDM+ C CR Sbjct: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450 >gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens] Length = 431 Score = 83.6 bits (205), Expect = 3e-16 Identities = 54/268 (20%), Positives = 106/268 (39%), Gaps = 43/268 (16%) Query: 190 LGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTCMKDQLEHPSA 249 LGR F +S+ + + W+ D+T+ V + + ++ + ++ + Q +P Sbjct: 202 LGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKL 261 Query: 250 QN--GLFNMTLVSPSLILYLNDTSA--QAYHSWYSLHYKRRPSQGPDQERSLSAYPVGEE 305 G P ++ + T ++ S S + S+ P + +L V E Sbjct: 262 AGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAEN 321 Query: 306 AAEDGRSSHHRHRRGQETVSSELKKPLGPASFNLSEYFRQFLLPQNECELHDFRLSFSQL 365 ++ D R + C+ H+ +SF L Sbjct: 322 SSSDQRQA---------------------------------------CKKHELYVSFRDL 342 Query: 366 KWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPRPSCVPAKYS 425 W +WI+AP Y YC+G+C + + H +VQ +++ +VP+P C P + + Sbjct: 343 GWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLN 402 Query: 426 PLSVLTIEPDGSIAYKEYEDMIATKCTC 453 +SVL + ++ K+Y +M+ C C Sbjct: 403 AISVLYFDDSSNVILKKYRNMVVRACGC 430 >gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sapiens] Length = 454 Score = 83.6 bits (205), Expect = 3e-16 Identities = 43/169 (25%), Positives = 78/169 (46%), Gaps = 11/169 (6%) Query: 289 QGPDQERS--LSAYPVGEEAAEDGRSSHHRHRRGQETVSS--ELKKPLGPASFNLSEYFR 344 QGP ++ ++ + E R+++ R + + SS + + +N SE Sbjct: 292 QGPQSKQPFMVAFFKASEVLLRSVRAANKRKNQNRNKSSSHQDSSRMSSVGDYNTSEQ-- 349 Query: 345 QFLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQN 404 + C+ H+ +SF L W +WI+AP Y YC G+C + + H +VQ Sbjct: 350 -----KQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQT 404 Query: 405 IIYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 +++ VP+P C P K + +SVL + ++ K+Y +M+ C C Sbjct: 405 LVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGC 453 >gi|48475062 growth differentiation factor 6 precursor [Homo sapiens] Length = 455 Score = 83.2 bits (204), Expect = 4e-16 Identities = 34/102 (33%), Positives = 54/102 (52%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDS 412 C ++F +L WD+WI+AP Y +C+G C + H ++Q ++ Sbjct: 354 CSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSMDPG 413 Query: 413 SVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 S P CVP K +P+S+L I+ ++ YK+YEDM+ C CR Sbjct: 414 STPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGCR 455 >gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sapiens] Length = 472 Score = 82.0 bits (201), Expect = 1e-15 Identities = 101/459 (22%), Positives = 173/459 (37%), Gaps = 101/459 (22%) Query: 70 SVGRGGSPRLQPDSRALHYMKKLYKTYATK---------EGIPKSNRSHLY---NTVRLF 117 + G G LQP + +M +LY Y+T EG + R L NTVR F Sbjct: 41 TAGGGPDSELQPQDKVSEHMLRLYDRYSTVQAARTPGSLEGGSQPWRPRLLREGNTVRSF 100 Query: 118 TPCTRHKQAPGDQVTGILPSVELLFNLDRITTVEHLLKSVLLYNINN--SVSFSSAVKCV 175 R A + G+ +FNL +T E++L + L + I ++S S V Sbjct: 101 ----RAAAAETLERKGLY-----IFNLTSLTKSENILSATLYFCIGELGNISLSCPVSGG 151 Query: 176 CN--------------LMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHK----WIQIDVT 217 C+ +K ++ S+ LG + K H+ W+ D+T Sbjct: 152 CSHHAQRKHIQIDLSAWTLKFSRNQSQLLGHL--------SVDMAKSHRDIMSWLSKDIT 203 Query: 218 SLLQPLVASNKRSIHMSINFTCMKDQLEHPSAQNGLFNMTLVSPSLILYLND-------- 269 LL+ A + N T QL + P +++Y ND Sbjct: 204 QLLRK--AKENEEFLIGFNITSKGRQLPKR-------RLPFPEPYILVYANDAAISEPES 254 Query: 270 --TSAQAYHSW---------------YSLHYKRRPSQG---PDQERSLSAYPVG---EEA 306 +S Q + ++ S+ +++ S G P Q L +E Sbjct: 255 VVSSLQGHRNFPTGTVPKWDSHIRAALSIERRKKRSTGVLLPLQNNELPGAEYQYKKDEV 314 Query: 307 AEDGRSSHHRHRRGQETVSSELKKPLGPASFNLSEYF----------RQFLLPQNECELH 356 E+ + + E ++ K+ GP + + F +Q++ P+N C Sbjct: 315 WEERKPYKTLQAQAPEKSKNKKKQRKGPHRKSQTLQFDEQTLKKARRKQWIEPRN-CARR 373 Query: 357 DFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK-LDSSVP 415 ++ F+ + W WI++P ++ YC G C + H +Q+I+ + +P Sbjct: 374 YLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVPGIP 433 Query: 416 RPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 P CVP K S LS+L + + ++ K Y +M C CR Sbjct: 434 EPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCACR 472 >gi|4503969 growth differentiation factor 5 preproprotein [Homo sapiens] Length = 501 Score = 80.1 bits (196), Expect = 4e-15 Identities = 33/102 (32%), Positives = 53/102 (51%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDS 412 C ++F + WD+WI+AP Y +C+G C + H ++Q ++ Sbjct: 400 CSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPE 459 Query: 413 SVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 S P CVP + SP+S+L I+ ++ YK+YEDM+ C CR Sbjct: 460 STPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR 501 >gi|222352098 nodal precursor [Homo sapiens] Length = 347 Score = 78.2 bits (191), Expect = 1e-14 Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Query: 333 GPASFNLSEYFRQFLLPQNE--CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAV 390 G S+ + R+ LP C F++ F+ + W +WI+ P +YN C+G+CP V Sbjct: 225 GQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPV 284 Query: 391 GHRYGSPVHTMVQNIIYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATK 450 G + H +Q+++ VP C P K PLS+L ++ +G + ++DMI + Sbjct: 285 GEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVD-NGRVLLDHHKDMIVEE 343 Query: 451 CTC 453 C C Sbjct: 344 CGC 346 >gi|10190670 growth differentiation factor 3 precursor [Homo sapiens] Length = 364 Score = 78.2 bits (191), Expect = 1e-14 Identities = 32/104 (30%), Positives = 58/104 (55%), Gaps = 1/104 (0%) Query: 350 QNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK 409 +N C H ++F L W WI+AP + YC G+CP ++ S + +Q +++ Sbjct: 261 KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMH-A 319 Query: 410 LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 +D +P+ C+P K SP+S+L + + ++ + YEDM+ +C C Sbjct: 320 VDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363 >gi|110349792 growth differentiation factor 1 [Homo sapiens] Length = 372 Score = 77.8 bits (190), Expect = 2e-14 Identities = 34/110 (30%), Positives = 58/110 (52%), Gaps = 4/110 (3%) Query: 349 PQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDC--PRAVGHRYGSPV--HTMVQN 404 P C +SF ++ W W++AP + YC+G C P A+ G P H +++ Sbjct: 263 PGGACRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSGSGGPPALNHAVLRA 322 Query: 405 IIYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 +++ + P CVPA+ SP+SVL + ++ ++YEDM+ +C CR Sbjct: 323 LMHAAAPGAADLPCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGCR 372 >gi|7705308 growth differentiation factor 2 [Homo sapiens] Length = 429 Score = 76.6 bits (187), Expect = 4e-14 Identities = 54/195 (27%), Positives = 80/195 (41%), Gaps = 18/195 (9%) Query: 261 PSLILYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLSAYPVGEEAAEDGRSSHHRHRRG 320 P +++ ND S+ + L R +QE L + + E G SSH G Sbjct: 252 PFFVVFSNDHSSGTKETRLEL----REMISHEQESVLKKLSK-DGSTEAGESSHEEDTDG 306 Query: 321 QETVSSELKKPLGPASFNLSEYFRQFLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPR 380 S L + A + C+ R++F + WD+WI+AP Y Sbjct: 307 HVAAGSTLARRKRSAGAG------------SHCQKTSLRVNFEDIGWDSWIIAPKEYEAY 354 Query: 381 YCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAY 440 CKG C + H +VQ +++ K + V + CVP K SP+SVL + G Sbjct: 355 ECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTL 414 Query: 441 K-EYEDMIATKCTCR 454 K YE M +C CR Sbjct: 415 KYHYEGMSVAECGCR 429 >gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sapiens] Length = 424 Score = 75.5 bits (184), Expect = 9e-14 Identities = 79/381 (20%), Positives = 145/381 (38%), Gaps = 54/381 (14%) Query: 88 YMKKLYKTYAT-KEGIPKSNRSHLYNTVRLFTPCTRHKQAPGDQVTGILPSVELLFNLDR 146 YM +LY +AT + +P +N + LF+ L LLFN+ Sbjct: 84 YMLELYNKFATDRTSMPSANIIRSFKNEDLFSQPVSFNG---------LRKYPLLFNVSI 134 Query: 147 ITTVEHLLKSVLLYNI--NNSVSFSSAVKCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFE 204 E ++ + LY + + + + + + + E K + G + + Sbjct: 135 PHHEEVIMAELRLYTLVQRDRMIYDGVDRKITIFEVLESKGDNE--GERNMLVLVSGEI- 191 Query: 205 FGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTCMKDQLEHPSAQNGLFNMTLVSPSLI 264 +G +W DVT ++ S + + ++ D+ E A +G + Sbjct: 192 YGTNSEWETFDVTDAIRRWQKSGSSTHQLEVHIESKHDEAE--DASSGRLEI-------- 241 Query: 265 LYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLSAYPVGEEAAEDGRSSHHRHRRGQETV 324 DTSAQ H+ + + S +++ L+ E+ E G ++ Sbjct: 242 ----DTSAQNKHNPLLIVFSDDQSSDKERKEELNEMISHEQLPE-------LDNLGLDSF 290 Query: 325 SSELKKPLGPASFNLSEYFRQFLLPQ----------NECELHDFRLSFSQLKWDNWIVAP 374 SS GP L + + N C+ + F ++ WD+WI+AP Sbjct: 291 SS------GPGEEALLQMRSNIIYDSTARIRRNAKGNYCKRTPLYIDFKEIGWDSWIIAP 344 Query: 375 HRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSSVPRPSCVPAKYSPLSVLTIEP 434 Y C+G C + H ++Q +++ K + CVP K P+S+L ++ Sbjct: 345 PGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLEPISILYLD- 403 Query: 435 DGSIAYK-EYEDMIATKCTCR 454 G + YK +YE M ++C CR Sbjct: 404 KGVVTYKFKYEGMAVSECGCR 424 >gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sapiens] Length = 402 Score = 74.7 bits (182), Expect = 2e-13 Identities = 28/101 (27%), Positives = 55/101 (54%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDS 412 C H+ +SF L W +W++AP Y+ YC+G+C + + H ++Q++++ + Sbjct: 301 CRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPD 360 Query: 413 SVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 +VP+ C P K S SVL + ++ +++ +M+ C C Sbjct: 361 AVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401 >gi|145611428 bone morphogenetic protein 8A [Homo sapiens] Length = 402 Score = 73.6 bits (179), Expect = 4e-13 Identities = 28/101 (27%), Positives = 55/101 (54%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDS 412 C H+ +SF L W +W++AP Y+ YC+G+C + + H ++Q++++ + Sbjct: 301 CRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMKPN 360 Query: 413 SVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 +VP+ C P K S SVL + ++ +++ +M+ C C Sbjct: 361 AVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401 >gi|153792495 growth differentiation factor 15 [Homo sapiens] Length = 308 Score = 69.3 bits (168), Expect = 7e-12 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 4/105 (3%) Query: 349 PQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYE 408 P C LH R S L W +W+++P C G CP + +H ++ ++ Sbjct: 207 PGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACP---SQFRAANMHAQIKTSLHR 263 Query: 409 KLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 +VP P CVPA Y+P+ VL + D ++ + Y+D++A C C Sbjct: 264 LKPDTVPAPCCVPASYNPM-VLIQKTDTGVSLQTYDDLLAKDCHC 307 >gi|239757187 PREDICTED: similar to growth differentiation factor 15 [Homo sapiens] Length = 270 Score = 69.3 bits (168), Expect = 7e-12 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 4/105 (3%) Query: 349 PQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYE 408 P C LH R S L W +W+++P C G CP + +H ++ ++ Sbjct: 169 PGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACP---SQFRAANMHAQIKTSLHR 225 Query: 409 KLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 +VP P CVPA Y+P+ VL + D ++ + Y+D++A C C Sbjct: 226 LKPDTVPAPCCVPASYNPM-VLIQKTDTGVSLQTYDDLLAKDCHC 269 >gi|4504699 inhibin beta A precursor [Homo sapiens] Length = 426 Score = 68.2 bits (165), Expect = 1e-11 Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 28/169 (16%) Query: 290 GPDQERSLSAYP-VGEEAAEDGRSSHHRHRRGQETVSSELKKPLGPASFNLSEYFRQFLL 348 G D+E+ S P + +A + H R RRG E Sbjct: 280 GADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKV--------------------- 318 Query: 349 PQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYE 408 N C F +SF + W++WI+AP Y+ YC+G+CP + GS + I + Sbjct: 319 --NICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHY 376 Query: 409 KLDSSVP----RPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 ++ P + CVP K P+S+L + +I K+ ++MI +C C Sbjct: 377 RMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGC 425 >gi|13899338 activin beta E [Homo sapiens] Length = 350 Score = 64.7 bits (156), Expect = 2e-10 Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 8/106 (7%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSP-VHTMVQNIIYEKLD 411 C D + F +L W +WI+ P Y YC G CP H GSP + + ++ L Sbjct: 247 CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCP---PHLAGSPGIAASFHSAVFSLLK 303 Query: 412 SSVPRPS----CVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 ++ P P+ CVP PLS+L ++ +G++ + DM+ C C Sbjct: 304 ANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349 >gi|4826740 growth differentiation factor 10 precursor [Homo sapiens] Length = 478 Score = 63.2 bits (152), Expect = 5e-10 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 1/103 (0%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK-LD 411 C ++ F+ + W+ WI++P ++ YC G C + H +Q+I+ + Sbjct: 376 CSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGII 435 Query: 412 SSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454 +P P CVP K + L VL ++ + ++ K Y +M C CR Sbjct: 436 PGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR 478 >gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens] Length = 407 Score = 61.2 bits (147), Expect = 2e-09 Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 3/106 (2%) Query: 351 NECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYG--SPVHTMVQNIIYE 408 N C F + F + W++WI+AP Y YC+G CP + G S HT V N Sbjct: 301 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM 360 Query: 409 K-LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 + L+ C+P K S +S+L + + +I ++ +MI +C C Sbjct: 361 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406 >gi|5031795 inhibin beta C chain preproprotein [Homo sapiens] Length = 352 Score = 57.8 bits (138), Expect = 2e-08 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%) Query: 353 CELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYG--SPVHTMVQNIIYEKL 410 C +F + F ++ W +WI+ P Y +C G CP + G + HT V N++ Sbjct: 247 CCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANT 306 Query: 411 DSSVP--RPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 + CVP PLS+L + D +I + DM+ C C Sbjct: 307 AAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351 >gi|4885259 myostatin [Homo sapiens] Length = 375 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 350 QNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK 409 ++ C + + F WD WI+AP RY YC G+C +Y HT +++++ Sbjct: 278 ESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFLQKY---PHT---HLVHQA 330 Query: 410 LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 P C P K SP+++L I Y + M+ +C C Sbjct: 331 NPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGC 374 >gi|5031613 growth differentiation factor 11 precursor [Homo sapiens] Length = 407 Score = 56.6 bits (135), Expect = 5e-08 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 7/104 (6%) Query: 350 QNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK 409 ++ C + + F WD WI+AP RY YC G C +Y HT +++ + Sbjct: 310 ESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGQCEYMFMQKY---PHT---HLVQQA 362 Query: 410 LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTC 453 P C P K SP+++L I Y + M+ +C C Sbjct: 363 NPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGC 406 >gi|4504697 inhibin alpha subunit precursor [Homo sapiens] Length = 366 Score = 45.8 bits (107), Expect = 8e-05 Identities = 33/128 (25%), Positives = 49/128 (38%), Gaps = 7/128 (5%) Query: 331 PLGPASFNLSEYFRQFLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAV 390 P P++ L + + C +SF +L W+ WIV P + YC G C + Sbjct: 240 PWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHI 299 Query: 391 GHRYGSPV----HTMVQNIIYEKLDSSVPRPSCVPAKYSPLSVLTIEPDG-SIAYKEYED 445 PV T Q Y L + P + +P PL V T G S Y+ + Sbjct: 300 PPNLSLPVPGAPPTPAQP--YSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPN 357 Query: 446 MIATKCTC 453 ++ C C Sbjct: 358 LLTQHCAC 365 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,518,321 Number of Sequences: 37866 Number of extensions: 857391 Number of successful extensions: 1979 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 1913 Number of HSP's gapped (non-prelim): 55 length of query: 454 length of database: 18,247,518 effective HSP length: 106 effective length of query: 348 effective length of database: 14,233,722 effective search space: 4953335256 effective search space used: 4953335256 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.