Guide to the Human Genome
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Search of human proteins with 4827024

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4827024 T-box 19 [Homo sapiens]
         (448 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4827024 T-box 19 [Homo sapiens]                                    936   0.0  
gi|4507339 transcription factor T [Homo sapiens]                      464   e-131
gi|18201894 T-box 5 isoform 3 [Homo sapiens]                          194   1e-49
gi|18201892 T-box 5 isoform 1 [Homo sapiens]                          194   1e-49
gi|31652232 T-box 5 isoform 1 [Homo sapiens]                          194   1e-49
gi|18201896 T-box 5 isoform 2 [Homo sapiens]                          194   2e-49
gi|5730081 T-box, brain, 1 [Homo sapiens]                             194   2e-49
gi|18201900 T-box 6 [Homo sapiens]                                    192   5e-49
gi|18129690 T-box 4 [Homo sapiens]                                    190   2e-48
gi|7019549 T-box 21 [Homo sapiens]                                    187   2e-47
gi|122937456 T-box 18 [Homo sapiens]                                  181   1e-45
gi|197333868 T-box 2 [Homo sapiens]                                   179   6e-45
gi|117676399 T-box transcription factor TBX20 [Homo sapiens]          177   2e-44
gi|158187509 T-box 22 isoform 1 [Homo sapiens]                        175   7e-44
gi|18375603 T-box 22 isoform 1 [Homo sapiens]                         175   7e-44
gi|55770860 T-box 15 [Homo sapiens]                                   174   1e-43
gi|32567784 T-box 10 [Homo sapiens]                                   172   7e-43
gi|22538470 eomesodermin [Homo sapiens]                               171   9e-43
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]                  170   2e-42
gi|5174711 T-box 1 isoform B [Homo sapiens]                           169   4e-42
gi|18104952 T-box 1 isoform C [Homo sapiens]                          169   4e-42
gi|18104950 T-box 1 isoform A [Homo sapiens]                          169   4e-42
gi|122937388 MAX gene associated [Homo sapiens]                       169   4e-42
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]                  166   5e-41
gi|158187511 T-box 22 isoform 2 [Homo sapiens]                        140   2e-33
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           40   0.004
gi|124378039 SEC16 homolog A [Homo sapiens]                            39   0.010
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]    39   0.012
gi|22538422 activating transcription factor 2 [Homo sapiens]           37   0.028
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    37   0.028

>gi|4827024 T-box 19 [Homo sapiens]
          Length = 448

 Score =  936 bits (2420), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNE 60
           MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNE
Sbjct: 1   MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNE 60

Query: 61  MIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHS 120
           MIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHS
Sbjct: 61  MIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHS 120

Query: 121 CVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM 180
           CVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM
Sbjct: 121 CVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM 180

Query: 181 VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTY 240
           VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTY
Sbjct: 181 VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTY 240

Query: 241 SHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHR 300
           SHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHR
Sbjct: 241 SHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHR 300

Query: 301 NHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTIS 360
           NHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTIS
Sbjct: 301 NHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTIS 360

Query: 361 NGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420
           NGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST
Sbjct: 361 NGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420

Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSLDG 448
           WTAVASHPFAGWGGPGAGGHHSPSSLDG
Sbjct: 421 WTAVASHPFAGWGGPGAGGHHSPSSLDG 448


>gi|4507339 transcription factor T [Homo sapiens]
          Length = 435

 Score =  464 bits (1194), Expect = e-131
 Identities = 243/427 (56%), Positives = 293/427 (68%), Gaps = 12/427 (2%)

Query: 3   MSELGTR---KPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTN 59
           MS  GT    K     V HLL+ VE+ELQAG EKGDPTE++L++ LE++ LW RFKE+TN
Sbjct: 1   MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESELWLRFKELTN 60

Query: 60  EMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSH 119
           EMIVTKNGRRMFPVLK++V+GLDPNAMYS LLDFV  D+HRWKYVNGEWVP GKPE  + 
Sbjct: 61  EMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAP 120

Query: 120 SCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHR 179
           SCVYIHPDSPNFGAHWMKAP+SFSKVKLTNKLNGGGQIMLNSLHKYEP++HIVRVG   R
Sbjct: 121 SCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQR 180

Query: 180 MVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVT 239
           M+T+  FPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER+  +++ E   +SQ   
Sbjct: 181 MITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHKEMMEEPGDSQQPG 240

Query: 240 YSHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMH 299
           YS   GW+      +C   N + Q+   L LP+ H+   C+ Y  LR HR +PYPS Y H
Sbjct: 241 YSQ-WGWLLPGTSTLCPPANPHPQFGGALSLPSTHS---CDRYPTLRSHRSSPYPSPYAH 296

Query: 300 RNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTI 359
           RN+SP+ +  ++S   L +    D+W+SL    H S+L V H   P     S YP LW++
Sbjct: 297 RNNSPTYS--DNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASP-PTSSSQYPSLWSV 353

Query: 360 SNGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVL-GEPSLTSIAV 418
           SNGA  P      V       F  G+PA  + P      AP+S+G  +  G  + T I  
Sbjct: 354 SNGAVTPGSQAAAVSNGLGAQFFRGSPAHYT-PLTHPVSAPSSSGSPLYEGAAAATDIVD 412

Query: 419 STWTAVA 425
           S + A A
Sbjct: 413 SQYDAAA 419


>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
          Length = 468

 Score =  194 bits (493), Expect = 1e-49
 Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           +++ L +  LW +F EV  EMI+TK GRRMFP  K+ VTGL+P   Y LL+D VP D HR
Sbjct: 4   IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63

Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159
           +K+ + +W   GK E +    +Y+HPDSP  GAHWM+  +SF K+KLTN  L+  G I+L
Sbjct: 64  YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 123

Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213
           NS+HKY+P++HIV+       GS +       FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 124 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 183

Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250
           K F       L    R   ++ P                   SES+ ++ S   G  +  
Sbjct: 184 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 243

Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306
            +GV  +G S      P P P P  H    H +  +         PY   YM  + S   
Sbjct: 244 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 301

Query: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366
           +   SS    Q      S+ + S+   A + +         P   P P L  IS     P
Sbjct: 302 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 352

Query: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420
           S P         V       +   +   TS P V     P  AG+   G P L       
Sbjct: 353 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 407

Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446
            T+VA  P     GP   G  SP +L
Sbjct: 408 QTSVAHQPVVRQCGPQT-GLQSPGTL 432


>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score =  194 bits (493), Expect = 1e-49
 Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           +++ L +  LW +F EV  EMI+TK GRRMFP  K+ VTGL+P   Y LL+D VP D HR
Sbjct: 54  IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113

Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159
           +K+ + +W   GK E +    +Y+HPDSP  GAHWM+  +SF K+KLTN  L+  G I+L
Sbjct: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173

Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213
           NS+HKY+P++HIV+       GS +       FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233

Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250
           K F       L    R   ++ P                   SES+ ++ S   G  +  
Sbjct: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293

Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306
            +GV  +G S      P P P P  H    H +  +         PY   YM  + S   
Sbjct: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 351

Query: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366
           +   SS    Q      S+ + S+   A + +         P   P P L  IS     P
Sbjct: 352 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 402

Query: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420
           S P         V       +   +   TS P V     P  AG+   G P L       
Sbjct: 403 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 457

Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446
            T+VA  P     GP   G  SP +L
Sbjct: 458 QTSVAHQPVVRQCGPQT-GLQSPGTL 482


>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score =  194 bits (493), Expect = 1e-49
 Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           +++ L +  LW +F EV  EMI+TK GRRMFP  K+ VTGL+P   Y LL+D VP D HR
Sbjct: 54  IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113

Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159
           +K+ + +W   GK E +    +Y+HPDSP  GAHWM+  +SF K+KLTN  L+  G I+L
Sbjct: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173

Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213
           NS+HKY+P++HIV+       GS +       FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233

Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250
           K F       L    R   ++ P                   SES+ ++ S   G  +  
Sbjct: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293

Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306
            +GV  +G S      P P P P  H    H +  +         PY   YM  + S   
Sbjct: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 351

Query: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366
           +   SS    Q      S+ + S+   A + +         P   P P L  IS     P
Sbjct: 352 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 402

Query: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420
           S P         V       +   +   TS P V     P  AG+   G P L       
Sbjct: 403 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 457

Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446
            T+VA  P     GP   G  SP +L
Sbjct: 458 QTSVAHQPVVRQCGPQT-GLQSPGTL 482


>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
          Length = 349

 Score =  194 bits (492), Expect = 2e-49
 Identities = 113/288 (39%), Positives = 156/288 (54%), Gaps = 32/288 (11%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           +++ L +  LW +F EV  EMI+TK GRRMFP  K+ VTGL+P   Y LL+D VP D HR
Sbjct: 54  IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113

Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159
           +K+ + +W   GK E +    +Y+HPDSP  GAHWM+  +SF K+KLTN  L+  G I+L
Sbjct: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173

Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213
           NS+HKY+P++HIV+       GS +       FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233

Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250
           K F       L    R   ++ P                   SES+ ++ S   G  +  
Sbjct: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293

Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYM 298
            +GV  +G S      P P P P  H    H +  +G    P+   ++
Sbjct: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKGECDHPWSICFL 339


>gi|5730081 T-box, brain, 1 [Homo sapiens]
          Length = 682

 Score =  194 bits (492), Expect = 2e-49
 Identities = 114/277 (41%), Positives = 151/277 (54%), Gaps = 25/277 (9%)

Query: 42  QIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRW 101
           Q+ L + PLW +F     EMI+TK GRRMFP L  +++GLDP A Y++ +D +  D + W
Sbjct: 205 QVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHW 264

Query: 102 KYVNGEWVPAGKPEVS-SHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL----NGGGQ 156
           ++  G+WVP GK + +   + VY+HPDSPN GAHWM+  ISF K+KLTN      N G  
Sbjct: 265 RFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQM 324

Query: 157 IMLNSLHKYEPQVHIVRVG-------SAHRMVTNCSFPETQFIAVTAYQNEEITALKIKY 209
           ++L SLHKY+P++H+V V        S    V   +FPETQFIAVTAYQN +IT LKI +
Sbjct: 325 VVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDH 384

Query: 210 NPFAKAFLD-------AKERNHLRDVPEAISESQHV---TYSHLGGWIFSNPDGVCTAGN 259
           NPFAK F D         + + L   P     SQ V    Y+  G   F     V     
Sbjct: 385 NPFAKGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGS--FLQDQFVSNYAK 442

Query: 260 SNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSA 296
           + +   A    P P T     H +GL   +QA  P A
Sbjct: 443 ARFHPGAGAG-PGPGTDRSVPHTNGLLSPQQAEDPGA 478


>gi|18201900 T-box 6 [Homo sapiens]
          Length = 436

 Score =  192 bits (488), Expect = 5e-49
 Identities = 123/304 (40%), Positives = 162/304 (53%), Gaps = 45/304 (14%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           + + LE+  LW+ F  V  EMI+TK GRRMFP  ++SVTGLDP A Y  LLD +P D  R
Sbjct: 91  VSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGAR 150

Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159
           +++    W P+GK E      VYIHPDSP  GAHWM+ P+SF +VKLTN  L+  G ++L
Sbjct: 151 YRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLIL 210

Query: 160 NSLHKYEPQVHIVRVG---SAH-RMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKA 215
           +S+HKY+P++H+VR     S H   + +  FPET FI+VTAYQN +IT LKI  NPFAK 
Sbjct: 211 HSMHKYQPRIHLVRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKG 270

Query: 216 F----------LDAKERNHLRDVPEAISESQ-------HVTYSHLGGWI-FSNPDGVCTA 257
           F           DA+ +  LR    A +E+            S LGG I  S+P+     
Sbjct: 271 FRENGRNCKRERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAP 330

Query: 258 GNSNYQYAAPLPLPA----------PHTHHGCEHYSGLR---------GHRQAPYPSAYM 298
           G +    AAP PL            P   HG   +   R           R APY +A++
Sbjct: 331 GEAT---AAPAPLCGGPSAEAYLLHPAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFL 387

Query: 299 HRNH 302
              H
Sbjct: 388 ELPH 391


>gi|18129690 T-box 4 [Homo sapiens]
          Length = 545

 Score =  190 bits (483), Expect = 2e-48
 Identities = 92/189 (48%), Positives = 128/189 (67%), Gaps = 7/189 (3%)

Query: 35  DPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFV 94
           + T + +++ L +  LW++F E   EMI+TK GRRMFP  K+ VTG++P   Y LL+D V
Sbjct: 61  EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV 120

Query: 95  PTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNG 153
           P D HR+K+ + +W+ AGK E +    +Y+HPDSP  GAHWM+  +SF K+KLTN  L+ 
Sbjct: 121 PADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDP 180

Query: 154 GGQIMLNSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKI 207
            G I+LNS+HKY+P++HIV+       GS +       FPET FI+VT+YQN +IT LKI
Sbjct: 181 FGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKI 240

Query: 208 KYNPFAKAF 216
           + NPFAK F
Sbjct: 241 ENNPFAKGF 249


>gi|7019549 T-box 21 [Homo sapiens]
          Length = 535

 Score =  187 bits (475), Expect = 2e-47
 Identities = 131/358 (36%), Positives = 169/358 (47%), Gaps = 49/358 (13%)

Query: 40  QLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSH 99
           +L++ L +  LW +F +   EMI+TK GRRMFP L  +V GL+P + Y + +D V  D H
Sbjct: 136 KLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQH 195

Query: 100 RWKYVNGEWVPAGKPEVS-SHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGG--- 155
            W+Y +G+WV  GK E S   + +Y+HPDSPN GAHWM+  +SF K+KLTN         
Sbjct: 196 HWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVT 255

Query: 156 -QIMLNSLHKYEPQVHIVRVGSAH-RMVTNCS------FPETQFIAVTAYQNEEITALKI 207
             I+L SLHKY+P++HIV V         N S      F ETQFIAVTAYQN EIT LKI
Sbjct: 256 QMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKI 315

Query: 208 KYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCT-AGNSNYQYAA 266
             NPFAK F                 E+    Y+ +   I S P   C   G  +Y    
Sbjct: 316 DNNPFAKGF----------------RENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLL 359

Query: 267 PLPLPAPHTHHGCEHYSGLRGHRQAPYPSAY---MHRNHSPSVNLIESSSNNLQVFSGPD 323
           P   P P        Y  L G  +   P AY     R+HS        S     + S P 
Sbjct: 360 PNQYPVP-----SRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPG 414

Query: 324 SWTSLSSTPHASILSVPHTNGPINP--GPSPYPCLW-------TISNGAGGPSGPGPE 372
              ++S      +L+ P    P+ P   P   P  W        +  G GG  G GPE
Sbjct: 415 --PTMSYYRGQEVLA-PGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPE 469


>gi|122937456 T-box 18 [Homo sapiens]
          Length = 607

 Score =  181 bits (459), Expect = 1e-45
 Identities = 106/258 (41%), Positives = 149/258 (57%), Gaps = 20/258 (7%)

Query: 36  PTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVP 95
           P+ +  ++ L+ A LW+RF E+  EMI+TK GRRMFP +++ ++GLDP+  Y + +D VP
Sbjct: 134 PSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVP 193

Query: 96  TDSHRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLT-NKLN 152
            D+ R++YV  + +W+ AG  +      VYIHPDSP  G  WM+  ISF K+KLT N+L+
Sbjct: 194 VDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELD 253

Query: 153 GGGQIMLNSLHKYEPQVHIVRVGSAHRM-----------VTNCSFPETQFIAVTAYQNEE 201
             G I+L+S+HKY+P+VH++R      +           V   SFPET F  VTAYQN++
Sbjct: 254 DQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQ 313

Query: 202 ITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGN-- 259
           IT LKI  NPFAK F D+  RN +    EA+ ES       L    F +  G+   GN  
Sbjct: 314 ITRLKIDRNPFAKGFRDS-GRNRMG--LEALVESYAFWRPSLRTLTFEDIPGIPKQGNAS 370

Query: 260 -SNYQYAAPLPLPAPHTH 276
            S         +PA H H
Sbjct: 371 SSTLLQGTGNGVPATHPH 388


>gi|197333868 T-box 2 [Homo sapiens]
          Length = 712

 Score =  179 bits (453), Expect = 6e-45
 Identities = 91/192 (47%), Positives = 120/192 (62%), Gaps = 5/192 (2%)

Query: 32  EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91
           E  D  E   ++ LE   LW +F ++  EM++TK+GRRMFP  K+ V+GLD  A Y LL+
Sbjct: 96  EPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLM 155

Query: 92  DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151
           D V  D  R+K+ N  W+ AGK +      +YIHPDSP  G  WM  P++F K+KLTN +
Sbjct: 156 DIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNI 215

Query: 152 NG-GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSFPETQFIAVTAYQNEEITALK 206
           +   G  +LNS+HKY+P+ HIVR     ++         FPET FIAVTAYQN++IT LK
Sbjct: 216 SDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLK 275

Query: 207 IKYNPFAKAFLD 218
           I  NPFAK F D
Sbjct: 276 IDNNPFAKGFRD 287


>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
          Length = 447

 Score =  177 bits (448), Expect = 2e-44
 Identities = 126/352 (35%), Positives = 179/352 (50%), Gaps = 49/352 (13%)

Query: 36  PTEKQLQII--LEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDF 93
           P+E+  +I   LE   LW +F E+  EMI+TK+GRRMFP +++S +G+DP A Y +L+D 
Sbjct: 93  PSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDI 152

Query: 94  VPTDSHRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLT-NK 150
           VP D+ R++Y      W+ AGK +    + +Y+HPDSP  G   +K  +SF KVKLT N+
Sbjct: 153 VPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNE 212

Query: 151 LNGGGQIMLNSLHKYEPQVHIVRVGSAHRMVTNCS--------FPETQFIAVTAYQNEEI 202
           L+  G I+LNS+HKY+P+VHI++       + N          FPET F AVTAYQN+ I
Sbjct: 213 LDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLI 272

Query: 203 TALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNY 262
           T LKI  NPFAK F D+   + L D+     ES    +S+                    
Sbjct: 273 TKLKIDSNPFAKGFRDS---SRLTDIERESVESLIQKHSY-------------------- 309

Query: 263 QYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGP 322
              A  P+    T+ G E   G          SA+   + + S++   SSS++   F  P
Sbjct: 310 ---ARSPI---RTYGGEEDVLGDESQTTPNRGSAFT-TSDNLSLSSWVSSSSSFPGFQHP 362

Query: 323 DSWTSLSSTPHASILSVPHTNGPINPGPSPYPCL---WTISNGAGGPSGPGP 371
            S T+L ++  +    +PH   PI     PY  L    T S  A    G GP
Sbjct: 363 QSLTALGTSTASIATPIPH---PIQGSLPPYSRLGMPLTPSAIASSMQGSGP 411


>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  175 bits (444), Expect = 7e-44
 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 20/207 (9%)

Query: 38  EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTD 97
           EK +Q+ L+ + LW+RF ++  EMI+TK GRRMFP +++ V GLDP   Y + +D VP D
Sbjct: 89  EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148

Query: 98  SHRWKYV--NGEWVPAGKPEVSSHSCV----YIHPDSPNFGAHWMKAPISFSKVKLT-NK 150
           S R++YV  + +W+ AG    + H C+    Y+HPDSP  G  WM+  ISF ++KLT N+
Sbjct: 149 SKRYRYVYHSSQWMVAGN---TDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE 205

Query: 151 LNGGGQIMLNSLHKYEPQVHIVRVGSAHRM----------VTNCSFPETQFIAVTAYQNE 200
           ++  G I+L S+HKY+P+VH++  GS+  +          V   SF ET+F  VTAYQN+
Sbjct: 206 MDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQ 265

Query: 201 EITALKIKYNPFAKAFLDAKERNHLRD 227
           +IT LKI+ NPFAK F D      + D
Sbjct: 266 QITKLKIERNPFAKGFRDTGRNRGVLD 292


>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  175 bits (444), Expect = 7e-44
 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 20/207 (9%)

Query: 38  EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTD 97
           EK +Q+ L+ + LW+RF ++  EMI+TK GRRMFP +++ V GLDP   Y + +D VP D
Sbjct: 89  EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148

Query: 98  SHRWKYV--NGEWVPAGKPEVSSHSCV----YIHPDSPNFGAHWMKAPISFSKVKLT-NK 150
           S R++YV  + +W+ AG    + H C+    Y+HPDSP  G  WM+  ISF ++KLT N+
Sbjct: 149 SKRYRYVYHSSQWMVAGN---TDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE 205

Query: 151 LNGGGQIMLNSLHKYEPQVHIVRVGSAHRM----------VTNCSFPETQFIAVTAYQNE 200
           ++  G I+L S+HKY+P+VH++  GS+  +          V   SF ET+F  VTAYQN+
Sbjct: 206 MDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQ 265

Query: 201 EITALKIKYNPFAKAFLDAKERNHLRD 227
           +IT LKI+ NPFAK F D      + D
Sbjct: 266 QITKLKIERNPFAKGFRDTGRNRGVLD 292


>gi|55770860 T-box 15 [Homo sapiens]
          Length = 496

 Score =  174 bits (441), Expect = 1e-43
 Identities = 90/207 (43%), Positives = 133/207 (64%), Gaps = 15/207 (7%)

Query: 39  KQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDS 98
           +++Q+ L+ A LW+RF ++  EMI+TK GRRMFP +++ +TGLDP+  Y + +D VP D+
Sbjct: 5   EEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDN 64

Query: 99  HRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLT-NKLNGGG 155
            R++YV  + +W+ AG  +      VYIHPDS   G  WM+  +SF K+KLT N+L+  G
Sbjct: 65  KRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQG 124

Query: 156 QIMLNSLHKYEPQVHIVRVGSAHRM-----------VTNCSFPETQFIAVTAYQNEEITA 204
            I+L+S+HKY+P+VH++R   +  +           V   +FPET F  VTAYQN++IT 
Sbjct: 125 HIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITR 184

Query: 205 LKIKYNPFAKAFLDA-KERNHLRDVPE 230
           LKI  NPFAK F D+ + R  L  + E
Sbjct: 185 LKIDRNPFAKGFRDSGRNRTGLEAIME 211


>gi|32567784 T-box 10 [Homo sapiens]
          Length = 385

 Score =  172 bits (435), Expect = 7e-43
 Identities = 109/297 (36%), Positives = 156/297 (52%), Gaps = 33/297 (11%)

Query: 30  GREKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSL 89
           G+   +P   ++ + LE  PLW+ F ++  EMIVTK GRRMFP  ++ + G+D  A Y+L
Sbjct: 54  GQGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYAL 113

Query: 90  LLDFVPTDSHRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKL 147
           L+DF+P D  R++Y   +  W+ AGK + ++   V+ HPDSP  GA WM+  +SF K+KL
Sbjct: 114 LMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKL 173

Query: 148 TNK-LNGGGQIMLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQN 199
           TN  L+  G I+LNS+H+Y+P+ H+V V         A     +  F ETQF AVTAYQN
Sbjct: 174 TNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQENFKSFIFTETQFTAVTAYQN 233

Query: 200 EEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFS---------N 250
             IT LKI  NPFAK F ++ + +     P  +      ++S L   +           N
Sbjct: 234 HRITQLKIASNPFAKGFRES-DLDSWPVAPRPLLSVPARSHSSLSPCVLKGATDREKDPN 292

Query: 251 PDGVCTAGNSNYQYAAPLPLP----APHTHHGCEH---YSGLRGH------RQAPYP 294
                T+    + +   LP P    AP T+    +   YSG   H      R APYP
Sbjct: 293 KASASTSKTPAWLHHQLLPPPEVLLAPATYRPVTYQSLYSGAPSHLGIPRTRPAPYP 349


>gi|22538470 eomesodermin [Homo sapiens]
          Length = 686

 Score =  171 bits (434), Expect = 9e-43
 Identities = 87/194 (44%), Positives = 121/194 (62%), Gaps = 12/194 (6%)

Query: 43  IILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWK 102
           + L + PLW +F     EMI+TK GRRMFP L  ++ GL+P A Y++ ++ V  D + W+
Sbjct: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328

Query: 103 YVNGEWVPAGKPEVSSH-SCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL----NGGGQI 157
           +  G+WV  GK + +   + +Y+HP+SPN G+HWM+  ISF K+KLTN      N    I
Sbjct: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388

Query: 158 MLNSLHKYEPQVHIVRVG-------SAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210
           +L SLHKY+P++HIV V        +        +F ETQFIAVTAYQN +IT LKI +N
Sbjct: 389 VLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHN 448

Query: 211 PFAKAFLDAKERNH 224
           PFAK F D  + +H
Sbjct: 449 PFAKGFRDNYDSSH 462


>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
          Length = 723

 Score =  170 bits (431), Expect = 2e-42
 Identities = 87/192 (45%), Positives = 118/192 (61%), Gaps = 5/192 (2%)

Query: 32  EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91
           E  +  E   ++ LE   LW +F +   EM++TK+GRRMFP  K+  +GLD  A Y LL+
Sbjct: 94  EPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLM 153

Query: 92  DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151
           D +  D  R+K+ N  W+ AGK +      +YIHPDSP  G  WM   ++F K+KLTN +
Sbjct: 154 DIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNI 213

Query: 152 NG-GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSFPETQFIAVTAYQNEEITALK 206
           +   G  +LNS+HKY+P+ HIVR     ++         FPET+FIAVTAYQN++IT LK
Sbjct: 214 SDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLK 273

Query: 207 IKYNPFAKAFLD 218
           I  NPFAK F D
Sbjct: 274 IDNNPFAKGFRD 285


>gi|5174711 T-box 1 isoform B [Homo sapiens]
          Length = 372

 Score =  169 bits (429), Expect = 4e-42
 Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           + + LE   LW  F ++  EMIVTK GRRMFP  ++ + G+DP A Y LL+DFVP D  R
Sbjct: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169

Query: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157
           ++Y   +  W+ AGK + ++   V+ HPDSP  GA WMK  +SF K+KLTN  L+  G I
Sbjct: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229

Query: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210
           +LNS+H+Y+P+ H+V V         A        F ET+F AVTAYQN  IT LKI  N
Sbjct: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289

Query: 211 PFAKAFLDAK----ERNH 224
           PFAK F D       RNH
Sbjct: 290 PFAKGFRDCDPEDWPRNH 307


>gi|18104952 T-box 1 isoform C [Homo sapiens]
          Length = 495

 Score =  169 bits (429), Expect = 4e-42
 Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           + + LE   LW  F ++  EMIVTK GRRMFP  ++ + G+DP A Y LL+DFVP D  R
Sbjct: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169

Query: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157
           ++Y   +  W+ AGK + ++   V+ HPDSP  GA WMK  +SF K+KLTN  L+  G I
Sbjct: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229

Query: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210
           +LNS+H+Y+P+ H+V V         A        F ET+F AVTAYQN  IT LKI  N
Sbjct: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289

Query: 211 PFAKAFLDAK----ERNH 224
           PFAK F D       RNH
Sbjct: 290 PFAKGFRDCDPEDWPRNH 307


>gi|18104950 T-box 1 isoform A [Homo sapiens]
          Length = 398

 Score =  169 bits (429), Expect = 4e-42
 Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%)

Query: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
           + + LE   LW  F ++  EMIVTK GRRMFP  ++ + G+DP A Y LL+DFVP D  R
Sbjct: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169

Query: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157
           ++Y   +  W+ AGK + ++   V+ HPDSP  GA WMK  +SF K+KLTN  L+  G I
Sbjct: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229

Query: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210
           +LNS+H+Y+P+ H+V V         A        F ET+F AVTAYQN  IT LKI  N
Sbjct: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289

Query: 211 PFAKAFLDAK----ERNH 224
           PFAK F D       RNH
Sbjct: 290 PFAKGFRDCDPEDWPRNH 307


>gi|122937388 MAX gene associated [Homo sapiens]
          Length = 3114

 Score =  169 bits (429), Expect = 4e-42
 Identities = 87/192 (45%), Positives = 121/192 (63%), Gaps = 8/192 (4%)

Query: 35  DPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFV 94
           D T   + + L++  +W  F   + EMI+TK GRRMFP  +  +TGLD N  Y L++D  
Sbjct: 69  DCTVGGITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDIS 128

Query: 95  PTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNG 153
           P D+HR+K+    W P+GK E      V+IHP+SP+ G +WM  P+SF K+KLTN  L+ 
Sbjct: 129 PVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQ 188

Query: 154 GGQIMLNSLHKYEPQVHIVRVGSAHRM-------VTNCSFPETQFIAVTAYQNEEITALK 206
            G I+L+S+H+Y P++H+V    A  +       V   +FP+T+F AVTAYQN +IT LK
Sbjct: 189 EGHIILHSMHRYLPRLHLVPAEKAVEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLK 248

Query: 207 IKYNPFAKAFLD 218
           I YNPFAK F D
Sbjct: 249 IDYNPFAKGFRD 260


>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
          Length = 743

 Score =  166 bits (419), Expect = 5e-41
 Identities = 88/212 (41%), Positives = 119/212 (56%), Gaps = 25/212 (11%)

Query: 32  EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91
           E  +  E   ++ LE   LW +F +   EM++TK+GRRMFP  K+  +GLD  A Y LL+
Sbjct: 94  EPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLM 153

Query: 92  DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151
           D +  D  R+K+ N  W+ AGK +      +YIHPDSP  G  WM   ++F K+KLTN +
Sbjct: 154 DIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNI 213

Query: 152 NG---------------------GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSF 186
           +                      G Q +LNS+HKY+P+ HIVR     ++         F
Sbjct: 214 SDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLF 273

Query: 187 PETQFIAVTAYQNEEITALKIKYNPFAKAFLD 218
           PET+FIAVTAYQN++IT LKI  NPFAK F D
Sbjct: 274 PETEFIAVTAYQNDKITQLKIDNNPFAKGFRD 305


>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
          Length = 400

 Score =  140 bits (354), Expect = 2e-33
 Identities = 75/175 (42%), Positives = 107/175 (61%), Gaps = 20/175 (11%)

Query: 70  MFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYV--NGEWVPAGKPEVSSHSCV----Y 123
           MFP +++ V GLDP   Y + +D VP DS R++YV  + +W+ AG  +   H C+    Y
Sbjct: 1   MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTD---HLCIIPRFY 57

Query: 124 IHPDSPNFGAHWMKAPISFSKVKLTN-KLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM-- 180
           +HPDSP  G  WM+  ISF ++KLTN +++  G I+L S+HKY+P+VH++  GS+  +  
Sbjct: 58  VHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQ 117

Query: 181 --------VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRD 227
                   V   SF ET+F  VTAYQN++IT LKI+ NPFAK F D      + D
Sbjct: 118 IQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLD 172


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 29/124 (23%)

Query: 339 VPHTNGPINP--------------GPSPYPCLWTISNGAGGPSGP----GPEVHASTPGA 380
           +P T GPI P               P P       + G  GP+GP    GP  H+  PG 
Sbjct: 447 IPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG- 505

Query: 381 FLLGNPAVTSPPS--------VLSTQAPTSAGVE-VLGEPSLTSIAVSTWTAVASHPFAG 431
            L G P    PP         + + Q P+ +G   V     +T + VS +T + S  +  
Sbjct: 506 -LPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPA 564

Query: 432 WGGP 435
            G P
Sbjct: 565 IGTP 568



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 31/105 (29%), Positives = 35/105 (33%), Gaps = 12/105 (11%)

Query: 344 GPINPGPSPYPCLWTISNGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSA 403
           GP   G    P L      AG P GPG +      G  L G P +T PP  +  Q P   
Sbjct: 294 GPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAG--LPGKPGLTGPPGNMGPQGPKG- 350

Query: 404 GVEVLGEPSLTSIAVSTWTAVASHPFAGWGGPGAGGHHSPSSLDG 448
              + G   L      T       P    G PGA G       DG
Sbjct: 351 ---IPGSHGLPGPKGET------GPAGPAGYPGAKGERGSPGSDG 386


>gi|124378039 SEC16 homolog A [Homo sapiens]
          Length = 2357

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 48/163 (29%), Positives = 64/163 (39%), Gaps = 24/163 (14%)

Query: 292  PYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGP- 350
            P PS     + SPSV L+ S+   L    GP     L+S     +  VP   GP+ PGP 
Sbjct: 1936 PAPSP---EHSSPSVRLLPSAPQTLP--DGP-----LASPARVPMFPVPLPPGPLEPGPG 1985

Query: 351  --SPYPCLWTISNGAGGPSGPG--PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVE 406
              +P P L     G   PSGPG  P V        LL   A +  P ++  +AP    + 
Sbjct: 1986 CVTPGPAL-----GFLEPSGPGLPPGVPPLQERRHLL-QEARSPDPGIVPQEAPVGNSLS 2039

Query: 407  VLGEPSLT---SIAVSTWTAVASHPFAGWGGPGAGGHHSPSSL 446
             L E +     +    + T   S    GW    +G    P SL
Sbjct: 2040 ELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSL 2082


>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
          Length = 753

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 59/224 (26%), Positives = 85/224 (37%), Gaps = 44/224 (19%)

Query: 225 LRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPL-PLPAPHTHHGCEHYS 283
           L D+P+A+  +   ++SH+   IF+      T+  S    ++P+ P PA  T    E   
Sbjct: 231 LEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTS----SSPIPPSPANCTTENSED-D 285

Query: 284 GLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILS-VPHT 342
             RG       S    +N S  V+    S+ + Q  + P ++ S    P AS LS  P  
Sbjct: 286 KKRGRSTDSEVSQSPAKNGSKPVH----SNQHPQSPAVPPTYPS-GPPPAASALSTTPGN 340

Query: 343 NGPINPGPSPYPCLWTISNGAGGPSGPGPEVHASTPGAFLLGNPAVTSP-PSVLSTQAPT 401
           NG   P   P        +  G  + P P  ++ TP  +     AV  P PS  ST  P 
Sbjct: 341 NGVPAPAAPP--------SALGPKASPAPSHNSGTPAPYA---QAVAPPAPSGPSTTQPR 389

Query: 402 SAGVEVLGEPSLTSIAVSTWTAVASHPFAGWGGPGAGGHHSPSS 445
              V+  G                     G GG G GG  S S+
Sbjct: 390 PPSVQPSG--------------------GGGGGSGGGGSSSSSN 413


>gi|22538422 activating transcription factor 2 [Homo sapiens]
          Length = 505

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 43/140 (30%), Positives = 57/140 (40%), Gaps = 16/140 (11%)

Query: 269 PLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHS---PSVNLIESSSNNLQVFSGPDSW 325
           PLP P +    E    L    Q   P++ + R  S   P+V L  S S+ +   + P   
Sbjct: 137 PLPHPESTTSDEKEVPLA---QTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVP--- 190

Query: 326 TSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGPSGPGPEVHAS---TPGAFL 382
              S T    I   P +N PI P P P+P L  + NG   P      + +S    P A  
Sbjct: 191 ---SPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVPAAVP 247

Query: 383 LGNPAVTSPPSVLSTQAPTS 402
           L  P VT  PSV     P+S
Sbjct: 248 LVRP-VTMVPSVPGIPGPSS 266


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 48/201 (23%), Positives = 67/201 (33%), Gaps = 41/201 (20%)

Query: 249  SNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHSPSVNL 308
            S PD    +   +  ++ PLP   P  HH   H+     H  AP P  + H  H P    
Sbjct: 974  SPPDTRVGSREKSLYHSGPLP---PAHHHPPHHH-----HHHAPPPQPHHHHAHPPHPPE 1025

Query: 309  IESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGPSG 368
            +E+  +       PD        P  ++   P   G    GPSP             P  
Sbjct: 1026 METGGS-------PD-----DPPPRLALGPQPSLRGWRGGGPSP------------TPGA 1061

Query: 369  PGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIA----VSTWTAV 424
            P P  H S       G    +  P++   Q P  A    +  P+ +       +   T V
Sbjct: 1062 PSPSHHGSAG-----GGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKV 1116

Query: 425  ASHPFAGWGGPGAGGHHSPSS 445
               P  G G P A    SP+S
Sbjct: 1117 EGEPQKGGGLPPAPSPTSPAS 1137


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,496,376
Number of Sequences: 37866
Number of extensions: 1223377
Number of successful extensions: 3925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 3534
Number of HSP's gapped (non-prelim): 576
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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