BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4827024 T-box 19 [Homo sapiens] (448 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4827024 T-box 19 [Homo sapiens] 936 0.0 gi|4507339 transcription factor T [Homo sapiens] 464 e-131 gi|18201894 T-box 5 isoform 3 [Homo sapiens] 194 1e-49 gi|18201892 T-box 5 isoform 1 [Homo sapiens] 194 1e-49 gi|31652232 T-box 5 isoform 1 [Homo sapiens] 194 1e-49 gi|18201896 T-box 5 isoform 2 [Homo sapiens] 194 2e-49 gi|5730081 T-box, brain, 1 [Homo sapiens] 194 2e-49 gi|18201900 T-box 6 [Homo sapiens] 192 5e-49 gi|18129690 T-box 4 [Homo sapiens] 190 2e-48 gi|7019549 T-box 21 [Homo sapiens] 187 2e-47 gi|122937456 T-box 18 [Homo sapiens] 181 1e-45 gi|197333868 T-box 2 [Homo sapiens] 179 6e-45 gi|117676399 T-box transcription factor TBX20 [Homo sapiens] 177 2e-44 gi|158187509 T-box 22 isoform 1 [Homo sapiens] 175 7e-44 gi|18375603 T-box 22 isoform 1 [Homo sapiens] 175 7e-44 gi|55770860 T-box 15 [Homo sapiens] 174 1e-43 gi|32567784 T-box 10 [Homo sapiens] 172 7e-43 gi|22538470 eomesodermin [Homo sapiens] 171 9e-43 gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] 170 2e-42 gi|5174711 T-box 1 isoform B [Homo sapiens] 169 4e-42 gi|18104952 T-box 1 isoform C [Homo sapiens] 169 4e-42 gi|18104950 T-box 1 isoform A [Homo sapiens] 169 4e-42 gi|122937388 MAX gene associated [Homo sapiens] 169 4e-42 gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] 166 5e-41 gi|158187511 T-box 22 isoform 2 [Homo sapiens] 140 2e-33 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 40 0.004 gi|124378039 SEC16 homolog A [Homo sapiens] 39 0.010 gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 39 0.012 gi|22538422 activating transcription factor 2 [Homo sapiens] 37 0.028 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 37 0.028 >gi|4827024 T-box 19 [Homo sapiens] Length = 448 Score = 936 bits (2420), Expect = 0.0 Identities = 448/448 (100%), Positives = 448/448 (100%) Query: 1 MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNE 60 MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNE Sbjct: 1 MAMSELGTRKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNE 60 Query: 61 MIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHS 120 MIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHS Sbjct: 61 MIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHS 120 Query: 121 CVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM 180 CVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM Sbjct: 121 CVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM 180 Query: 181 VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTY 240 VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTY Sbjct: 181 VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTY 240 Query: 241 SHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHR 300 SHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHR Sbjct: 241 SHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHR 300 Query: 301 NHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTIS 360 NHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTIS Sbjct: 301 NHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTIS 360 Query: 361 NGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420 NGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST Sbjct: 361 NGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420 Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSLDG 448 WTAVASHPFAGWGGPGAGGHHSPSSLDG Sbjct: 421 WTAVASHPFAGWGGPGAGGHHSPSSLDG 448 >gi|4507339 transcription factor T [Homo sapiens] Length = 435 Score = 464 bits (1194), Expect = e-131 Identities = 243/427 (56%), Positives = 293/427 (68%), Gaps = 12/427 (2%) Query: 3 MSELGTR---KPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTN 59 MS GT K V HLL+ VE+ELQAG EKGDPTE++L++ LE++ LW RFKE+TN Sbjct: 1 MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESELWLRFKELTN 60 Query: 60 EMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSH 119 EMIVTKNGRRMFPVLK++V+GLDPNAMYS LLDFV D+HRWKYVNGEWVP GKPE + Sbjct: 61 EMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAP 120 Query: 120 SCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHR 179 SCVYIHPDSPNFGAHWMKAP+SFSKVKLTNKLNGGGQIMLNSLHKYEP++HIVRVG R Sbjct: 121 SCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQR 180 Query: 180 MVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVT 239 M+T+ FPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER+ +++ E +SQ Sbjct: 181 MITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHKEMMEEPGDSQQPG 240 Query: 240 YSHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMH 299 YS GW+ +C N + Q+ L LP+ H+ C+ Y LR HR +PYPS Y H Sbjct: 241 YSQ-WGWLLPGTSTLCPPANPHPQFGGALSLPSTHS---CDRYPTLRSHRSSPYPSPYAH 296 Query: 300 RNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTI 359 RN+SP+ + ++S L + D+W+SL H S+L V H P S YP LW++ Sbjct: 297 RNNSPTYS--DNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASP-PTSSSQYPSLWSV 353 Query: 360 SNGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVL-GEPSLTSIAV 418 SNGA P V F G+PA + P AP+S+G + G + T I Sbjct: 354 SNGAVTPGSQAAAVSNGLGAQFFRGSPAHYT-PLTHPVSAPSSSGSPLYEGAAAATDIVD 412 Query: 419 STWTAVA 425 S + A A Sbjct: 413 SQYDAAA 419 >gi|18201894 T-box 5 isoform 3 [Homo sapiens] Length = 468 Score = 194 bits (493), Expect = 1e-49 Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 +++ L + LW +F EV EMI+TK GRRMFP K+ VTGL+P Y LL+D VP D HR Sbjct: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63 Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159 +K+ + +W GK E + +Y+HPDSP GAHWM+ +SF K+KLTN L+ G I+L Sbjct: 64 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 123 Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213 NS+HKY+P++HIV+ GS + FPET FIAVT+YQN +IT LKI+ NPFA Sbjct: 124 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 183 Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250 K F L R ++ P SES+ ++ S G + Sbjct: 184 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 243 Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306 +GV +G S P P P P H H + + PY YM + S Sbjct: 244 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 301 Query: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366 + SS Q S+ + S+ A + + P P P L IS P Sbjct: 302 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 352 Query: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420 S P V + + TS P V P AG+ G P L Sbjct: 353 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 407 Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446 T+VA P GP G SP +L Sbjct: 408 QTSVAHQPVVRQCGPQT-GLQSPGTL 432 >gi|18201892 T-box 5 isoform 1 [Homo sapiens] Length = 518 Score = 194 bits (493), Expect = 1e-49 Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 +++ L + LW +F EV EMI+TK GRRMFP K+ VTGL+P Y LL+D VP D HR Sbjct: 54 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113 Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159 +K+ + +W GK E + +Y+HPDSP GAHWM+ +SF K+KLTN L+ G I+L Sbjct: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173 Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213 NS+HKY+P++HIV+ GS + FPET FIAVT+YQN +IT LKI+ NPFA Sbjct: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233 Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250 K F L R ++ P SES+ ++ S G + Sbjct: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293 Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306 +GV +G S P P P P H H + + PY YM + S Sbjct: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 351 Query: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366 + SS Q S+ + S+ A + + P P P L IS P Sbjct: 352 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 402 Query: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420 S P V + + TS P V P AG+ G P L Sbjct: 403 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 457 Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446 T+VA P GP G SP +L Sbjct: 458 QTSVAHQPVVRQCGPQT-GLQSPGTL 482 >gi|31652232 T-box 5 isoform 1 [Homo sapiens] Length = 518 Score = 194 bits (493), Expect = 1e-49 Identities = 152/446 (34%), Positives = 204/446 (45%), Gaps = 57/446 (12%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 +++ L + LW +F EV EMI+TK GRRMFP K+ VTGL+P Y LL+D VP D HR Sbjct: 54 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113 Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159 +K+ + +W GK E + +Y+HPDSP GAHWM+ +SF K+KLTN L+ G I+L Sbjct: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173 Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213 NS+HKY+P++HIV+ GS + FPET FIAVT+YQN +IT LKI+ NPFA Sbjct: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233 Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250 K F L R ++ P SES+ ++ S G + Sbjct: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293 Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHR----QAPYPSAYMHRNHSPSV 306 +GV +G S P P P P H H + + PY YM + S Sbjct: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEED 351 Query: 307 NLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGP 366 + SS Q S+ + S+ A + + P P P L IS P Sbjct: 352 SFYRSSYPQQQGLGA--SYRTESAQRQACMYA------SSAPPSEPVPSLEDISCNT-WP 402 Query: 367 SGPG------PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIAVST 420 S P V + + TS P V P AG+ G P L Sbjct: 403 SMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLV-----PRLAGMANHGSPQLGEGMFQH 457 Query: 421 WTAVASHPFAGWGGPGAGGHHSPSSL 446 T+VA P GP G SP +L Sbjct: 458 QTSVAHQPVVRQCGPQT-GLQSPGTL 482 >gi|18201896 T-box 5 isoform 2 [Homo sapiens] Length = 349 Score = 194 bits (492), Expect = 2e-49 Identities = 113/288 (39%), Positives = 156/288 (54%), Gaps = 32/288 (11%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 +++ L + LW +F EV EMI+TK GRRMFP K+ VTGL+P Y LL+D VP D HR Sbjct: 54 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113 Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159 +K+ + +W GK E + +Y+HPDSP GAHWM+ +SF K+KLTN L+ G I+L Sbjct: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173 Query: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213 NS+HKY+P++HIV+ GS + FPET FIAVT+YQN +IT LKI+ NPFA Sbjct: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233 Query: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250 K F L R ++ P SES+ ++ S G + Sbjct: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293 Query: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYM 298 +GV +G S P P P P H H + +G P+ ++ Sbjct: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKGECDHPWSICFL 339 >gi|5730081 T-box, brain, 1 [Homo sapiens] Length = 682 Score = 194 bits (492), Expect = 2e-49 Identities = 114/277 (41%), Positives = 151/277 (54%), Gaps = 25/277 (9%) Query: 42 QIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRW 101 Q+ L + PLW +F EMI+TK GRRMFP L +++GLDP A Y++ +D + D + W Sbjct: 205 QVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHW 264 Query: 102 KYVNGEWVPAGKPEVS-SHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL----NGGGQ 156 ++ G+WVP GK + + + VY+HPDSPN GAHWM+ ISF K+KLTN N G Sbjct: 265 RFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQM 324 Query: 157 IMLNSLHKYEPQVHIVRVG-------SAHRMVTNCSFPETQFIAVTAYQNEEITALKIKY 209 ++L SLHKY+P++H+V V S V +FPETQFIAVTAYQN +IT LKI + Sbjct: 325 VVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDH 384 Query: 210 NPFAKAFLD-------AKERNHLRDVPEAISESQHV---TYSHLGGWIFSNPDGVCTAGN 259 NPFAK F D + + L P SQ V Y+ G F V Sbjct: 385 NPFAKGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGS--FLQDQFVSNYAK 442 Query: 260 SNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSA 296 + + A P P T H +GL +QA P A Sbjct: 443 ARFHPGAGAG-PGPGTDRSVPHTNGLLSPQQAEDPGA 478 >gi|18201900 T-box 6 [Homo sapiens] Length = 436 Score = 192 bits (488), Expect = 5e-49 Identities = 123/304 (40%), Positives = 162/304 (53%), Gaps = 45/304 (14%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 + + LE+ LW+ F V EMI+TK GRRMFP ++SVTGLDP A Y LLD +P D R Sbjct: 91 VSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGAR 150 Query: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159 +++ W P+GK E VYIHPDSP GAHWM+ P+SF +VKLTN L+ G ++L Sbjct: 151 YRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLIL 210 Query: 160 NSLHKYEPQVHIVRVG---SAH-RMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKA 215 +S+HKY+P++H+VR S H + + FPET FI+VTAYQN +IT LKI NPFAK Sbjct: 211 HSMHKYQPRIHLVRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKG 270 Query: 216 F----------LDAKERNHLRDVPEAISESQ-------HVTYSHLGGWI-FSNPDGVCTA 257 F DA+ + LR A +E+ S LGG I S+P+ Sbjct: 271 FRENGRNCKRERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAP 330 Query: 258 GNSNYQYAAPLPLPA----------PHTHHGCEHYSGLR---------GHRQAPYPSAYM 298 G + AAP PL P HG + R R APY +A++ Sbjct: 331 GEAT---AAPAPLCGGPSAEAYLLHPAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFL 387 Query: 299 HRNH 302 H Sbjct: 388 ELPH 391 >gi|18129690 T-box 4 [Homo sapiens] Length = 545 Score = 190 bits (483), Expect = 2e-48 Identities = 92/189 (48%), Positives = 128/189 (67%), Gaps = 7/189 (3%) Query: 35 DPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFV 94 + T + +++ L + LW++F E EMI+TK GRRMFP K+ VTG++P Y LL+D V Sbjct: 61 EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV 120 Query: 95 PTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNG 153 P D HR+K+ + +W+ AGK E + +Y+HPDSP GAHWM+ +SF K+KLTN L+ Sbjct: 121 PADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDP 180 Query: 154 GGQIMLNSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKI 207 G I+LNS+HKY+P++HIV+ GS + FPET FI+VT+YQN +IT LKI Sbjct: 181 FGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKI 240 Query: 208 KYNPFAKAF 216 + NPFAK F Sbjct: 241 ENNPFAKGF 249 >gi|7019549 T-box 21 [Homo sapiens] Length = 535 Score = 187 bits (475), Expect = 2e-47 Identities = 131/358 (36%), Positives = 169/358 (47%), Gaps = 49/358 (13%) Query: 40 QLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSH 99 +L++ L + LW +F + EMI+TK GRRMFP L +V GL+P + Y + +D V D H Sbjct: 136 KLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQH 195 Query: 100 RWKYVNGEWVPAGKPEVS-SHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGG--- 155 W+Y +G+WV GK E S + +Y+HPDSPN GAHWM+ +SF K+KLTN Sbjct: 196 HWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVT 255 Query: 156 -QIMLNSLHKYEPQVHIVRVGSAH-RMVTNCS------FPETQFIAVTAYQNEEITALKI 207 I+L SLHKY+P++HIV V N S F ETQFIAVTAYQN EIT LKI Sbjct: 256 QMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKI 315 Query: 208 KYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCT-AGNSNYQYAA 266 NPFAK F E+ Y+ + I S P C G +Y Sbjct: 316 DNNPFAKGF----------------RENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLL 359 Query: 267 PLPLPAPHTHHGCEHYSGLRGHRQAPYPSAY---MHRNHSPSVNLIESSSNNLQVFSGPD 323 P P P Y L G + P AY R+HS S + S P Sbjct: 360 PNQYPVP-----SRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPG 414 Query: 324 SWTSLSSTPHASILSVPHTNGPINP--GPSPYPCLW-------TISNGAGGPSGPGPE 372 ++S +L+ P P+ P P P W + G GG G GPE Sbjct: 415 --PTMSYYRGQEVLA-PGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPE 469 >gi|122937456 T-box 18 [Homo sapiens] Length = 607 Score = 181 bits (459), Expect = 1e-45 Identities = 106/258 (41%), Positives = 149/258 (57%), Gaps = 20/258 (7%) Query: 36 PTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVP 95 P+ + ++ L+ A LW+RF E+ EMI+TK GRRMFP +++ ++GLDP+ Y + +D VP Sbjct: 134 PSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVP 193 Query: 96 TDSHRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLT-NKLN 152 D+ R++YV + +W+ AG + VYIHPDSP G WM+ ISF K+KLT N+L+ Sbjct: 194 VDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELD 253 Query: 153 GGGQIMLNSLHKYEPQVHIVRVGSAHRM-----------VTNCSFPETQFIAVTAYQNEE 201 G I+L+S+HKY+P+VH++R + V SFPET F VTAYQN++ Sbjct: 254 DQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQ 313 Query: 202 ITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGN-- 259 IT LKI NPFAK F D+ RN + EA+ ES L F + G+ GN Sbjct: 314 ITRLKIDRNPFAKGFRDS-GRNRMG--LEALVESYAFWRPSLRTLTFEDIPGIPKQGNAS 370 Query: 260 -SNYQYAAPLPLPAPHTH 276 S +PA H H Sbjct: 371 SSTLLQGTGNGVPATHPH 388 >gi|197333868 T-box 2 [Homo sapiens] Length = 712 Score = 179 bits (453), Expect = 6e-45 Identities = 91/192 (47%), Positives = 120/192 (62%), Gaps = 5/192 (2%) Query: 32 EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91 E D E ++ LE LW +F ++ EM++TK+GRRMFP K+ V+GLD A Y LL+ Sbjct: 96 EPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLM 155 Query: 92 DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151 D V D R+K+ N W+ AGK + +YIHPDSP G WM P++F K+KLTN + Sbjct: 156 DIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNI 215 Query: 152 NG-GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSFPETQFIAVTAYQNEEITALK 206 + G +LNS+HKY+P+ HIVR ++ FPET FIAVTAYQN++IT LK Sbjct: 216 SDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLK 275 Query: 207 IKYNPFAKAFLD 218 I NPFAK F D Sbjct: 276 IDNNPFAKGFRD 287 >gi|117676399 T-box transcription factor TBX20 [Homo sapiens] Length = 447 Score = 177 bits (448), Expect = 2e-44 Identities = 126/352 (35%), Positives = 179/352 (50%), Gaps = 49/352 (13%) Query: 36 PTEKQLQII--LEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDF 93 P+E+ +I LE LW +F E+ EMI+TK+GRRMFP +++S +G+DP A Y +L+D Sbjct: 93 PSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDI 152 Query: 94 VPTDSHRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLT-NK 150 VP D+ R++Y W+ AGK + + +Y+HPDSP G +K +SF KVKLT N+ Sbjct: 153 VPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNE 212 Query: 151 LNGGGQIMLNSLHKYEPQVHIVRVGSAHRMVTNCS--------FPETQFIAVTAYQNEEI 202 L+ G I+LNS+HKY+P+VHI++ + N FPET F AVTAYQN+ I Sbjct: 213 LDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLI 272 Query: 203 TALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNY 262 T LKI NPFAK F D+ + L D+ ES +S+ Sbjct: 273 TKLKIDSNPFAKGFRDS---SRLTDIERESVESLIQKHSY-------------------- 309 Query: 263 QYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGP 322 A P+ T+ G E G SA+ + + S++ SSS++ F P Sbjct: 310 ---ARSPI---RTYGGEEDVLGDESQTTPNRGSAFT-TSDNLSLSSWVSSSSSFPGFQHP 362 Query: 323 DSWTSLSSTPHASILSVPHTNGPINPGPSPYPCL---WTISNGAGGPSGPGP 371 S T+L ++ + +PH PI PY L T S A G GP Sbjct: 363 QSLTALGTSTASIATPIPH---PIQGSLPPYSRLGMPLTPSAIASSMQGSGP 411 >gi|158187509 T-box 22 isoform 1 [Homo sapiens] Length = 520 Score = 175 bits (444), Expect = 7e-44 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 20/207 (9%) Query: 38 EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTD 97 EK +Q+ L+ + LW+RF ++ EMI+TK GRRMFP +++ V GLDP Y + +D VP D Sbjct: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148 Query: 98 SHRWKYV--NGEWVPAGKPEVSSHSCV----YIHPDSPNFGAHWMKAPISFSKVKLT-NK 150 S R++YV + +W+ AG + H C+ Y+HPDSP G WM+ ISF ++KLT N+ Sbjct: 149 SKRYRYVYHSSQWMVAGN---TDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE 205 Query: 151 LNGGGQIMLNSLHKYEPQVHIVRVGSAHRM----------VTNCSFPETQFIAVTAYQNE 200 ++ G I+L S+HKY+P+VH++ GS+ + V SF ET+F VTAYQN+ Sbjct: 206 MDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQ 265 Query: 201 EITALKIKYNPFAKAFLDAKERNHLRD 227 +IT LKI+ NPFAK F D + D Sbjct: 266 QITKLKIERNPFAKGFRDTGRNRGVLD 292 >gi|18375603 T-box 22 isoform 1 [Homo sapiens] Length = 520 Score = 175 bits (444), Expect = 7e-44 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 20/207 (9%) Query: 38 EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTD 97 EK +Q+ L+ + LW+RF ++ EMI+TK GRRMFP +++ V GLDP Y + +D VP D Sbjct: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148 Query: 98 SHRWKYV--NGEWVPAGKPEVSSHSCV----YIHPDSPNFGAHWMKAPISFSKVKLT-NK 150 S R++YV + +W+ AG + H C+ Y+HPDSP G WM+ ISF ++KLT N+ Sbjct: 149 SKRYRYVYHSSQWMVAGN---TDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE 205 Query: 151 LNGGGQIMLNSLHKYEPQVHIVRVGSAHRM----------VTNCSFPETQFIAVTAYQNE 200 ++ G I+L S+HKY+P+VH++ GS+ + V SF ET+F VTAYQN+ Sbjct: 206 MDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQ 265 Query: 201 EITALKIKYNPFAKAFLDAKERNHLRD 227 +IT LKI+ NPFAK F D + D Sbjct: 266 QITKLKIERNPFAKGFRDTGRNRGVLD 292 >gi|55770860 T-box 15 [Homo sapiens] Length = 496 Score = 174 bits (441), Expect = 1e-43 Identities = 90/207 (43%), Positives = 133/207 (64%), Gaps = 15/207 (7%) Query: 39 KQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDS 98 +++Q+ L+ A LW+RF ++ EMI+TK GRRMFP +++ +TGLDP+ Y + +D VP D+ Sbjct: 5 EEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDN 64 Query: 99 HRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLT-NKLNGGG 155 R++YV + +W+ AG + VYIHPDS G WM+ +SF K+KLT N+L+ G Sbjct: 65 KRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQG 124 Query: 156 QIMLNSLHKYEPQVHIVRVGSAHRM-----------VTNCSFPETQFIAVTAYQNEEITA 204 I+L+S+HKY+P+VH++R + + V +FPET F VTAYQN++IT Sbjct: 125 HIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITR 184 Query: 205 LKIKYNPFAKAFLDA-KERNHLRDVPE 230 LKI NPFAK F D+ + R L + E Sbjct: 185 LKIDRNPFAKGFRDSGRNRTGLEAIME 211 >gi|32567784 T-box 10 [Homo sapiens] Length = 385 Score = 172 bits (435), Expect = 7e-43 Identities = 109/297 (36%), Positives = 156/297 (52%), Gaps = 33/297 (11%) Query: 30 GREKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSL 89 G+ +P ++ + LE PLW+ F ++ EMIVTK GRRMFP ++ + G+D A Y+L Sbjct: 54 GQGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYAL 113 Query: 90 LLDFVPTDSHRWKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKL 147 L+DF+P D R++Y + W+ AGK + ++ V+ HPDSP GA WM+ +SF K+KL Sbjct: 114 LMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKL 173 Query: 148 TNK-LNGGGQIMLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQN 199 TN L+ G I+LNS+H+Y+P+ H+V V A + F ETQF AVTAYQN Sbjct: 174 TNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQENFKSFIFTETQFTAVTAYQN 233 Query: 200 EEITALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFS---------N 250 IT LKI NPFAK F ++ + + P + ++S L + N Sbjct: 234 HRITQLKIASNPFAKGFRES-DLDSWPVAPRPLLSVPARSHSSLSPCVLKGATDREKDPN 292 Query: 251 PDGVCTAGNSNYQYAAPLPLP----APHTHHGCEH---YSGLRGH------RQAPYP 294 T+ + + LP P AP T+ + YSG H R APYP Sbjct: 293 KASASTSKTPAWLHHQLLPPPEVLLAPATYRPVTYQSLYSGAPSHLGIPRTRPAPYP 349 >gi|22538470 eomesodermin [Homo sapiens] Length = 686 Score = 171 bits (434), Expect = 9e-43 Identities = 87/194 (44%), Positives = 121/194 (62%), Gaps = 12/194 (6%) Query: 43 IILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWK 102 + L + PLW +F EMI+TK GRRMFP L ++ GL+P A Y++ ++ V D + W+ Sbjct: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 Query: 103 YVNGEWVPAGKPEVSSH-SCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL----NGGGQI 157 + G+WV GK + + + +Y+HP+SPN G+HWM+ ISF K+KLTN N I Sbjct: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 Query: 158 MLNSLHKYEPQVHIVRVG-------SAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210 +L SLHKY+P++HIV V + +F ETQFIAVTAYQN +IT LKI +N Sbjct: 389 VLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHN 448 Query: 211 PFAKAFLDAKERNH 224 PFAK F D + +H Sbjct: 449 PFAKGFRDNYDSSH 462 >gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] Length = 723 Score = 170 bits (431), Expect = 2e-42 Identities = 87/192 (45%), Positives = 118/192 (61%), Gaps = 5/192 (2%) Query: 32 EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91 E + E ++ LE LW +F + EM++TK+GRRMFP K+ +GLD A Y LL+ Sbjct: 94 EPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLM 153 Query: 92 DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151 D + D R+K+ N W+ AGK + +YIHPDSP G WM ++F K+KLTN + Sbjct: 154 DIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNI 213 Query: 152 NG-GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSFPETQFIAVTAYQNEEITALK 206 + G +LNS+HKY+P+ HIVR ++ FPET+FIAVTAYQN++IT LK Sbjct: 214 SDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLK 273 Query: 207 IKYNPFAKAFLD 218 I NPFAK F D Sbjct: 274 IDNNPFAKGFRD 285 >gi|5174711 T-box 1 isoform B [Homo sapiens] Length = 372 Score = 169 bits (429), Expect = 4e-42 Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 + + LE LW F ++ EMIVTK GRRMFP ++ + G+DP A Y LL+DFVP D R Sbjct: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169 Query: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157 ++Y + W+ AGK + ++ V+ HPDSP GA WMK +SF K+KLTN L+ G I Sbjct: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229 Query: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210 +LNS+H+Y+P+ H+V V A F ET+F AVTAYQN IT LKI N Sbjct: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289 Query: 211 PFAKAFLDAK----ERNH 224 PFAK F D RNH Sbjct: 290 PFAKGFRDCDPEDWPRNH 307 >gi|18104952 T-box 1 isoform C [Homo sapiens] Length = 495 Score = 169 bits (429), Expect = 4e-42 Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 + + LE LW F ++ EMIVTK GRRMFP ++ + G+DP A Y LL+DFVP D R Sbjct: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169 Query: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157 ++Y + W+ AGK + ++ V+ HPDSP GA WMK +SF K+KLTN L+ G I Sbjct: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229 Query: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210 +LNS+H+Y+P+ H+V V A F ET+F AVTAYQN IT LKI N Sbjct: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289 Query: 211 PFAKAFLDAK----ERNH 224 PFAK F D RNH Sbjct: 290 PFAKGFRDCDPEDWPRNH 307 >gi|18104950 T-box 1 isoform A [Homo sapiens] Length = 398 Score = 169 bits (429), Expect = 4e-42 Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%) Query: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100 + + LE LW F ++ EMIVTK GRRMFP ++ + G+DP A Y LL+DFVP D R Sbjct: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169 Query: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157 ++Y + W+ AGK + ++ V+ HPDSP GA WMK +SF K+KLTN L+ G I Sbjct: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229 Query: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210 +LNS+H+Y+P+ H+V V A F ET+F AVTAYQN IT LKI N Sbjct: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289 Query: 211 PFAKAFLDAK----ERNH 224 PFAK F D RNH Sbjct: 290 PFAKGFRDCDPEDWPRNH 307 >gi|122937388 MAX gene associated [Homo sapiens] Length = 3114 Score = 169 bits (429), Expect = 4e-42 Identities = 87/192 (45%), Positives = 121/192 (63%), Gaps = 8/192 (4%) Query: 35 DPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFV 94 D T + + L++ +W F + EMI+TK GRRMFP + +TGLD N Y L++D Sbjct: 69 DCTVGGITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDIS 128 Query: 95 PTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNG 153 P D+HR+K+ W P+GK E V+IHP+SP+ G +WM P+SF K+KLTN L+ Sbjct: 129 PVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQ 188 Query: 154 GGQIMLNSLHKYEPQVHIVRVGSAHRM-------VTNCSFPETQFIAVTAYQNEEITALK 206 G I+L+S+H+Y P++H+V A + V +FP+T+F AVTAYQN +IT LK Sbjct: 189 EGHIILHSMHRYLPRLHLVPAEKAVEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLK 248 Query: 207 IKYNPFAKAFLD 218 I YNPFAK F D Sbjct: 249 IDYNPFAKGFRD 260 >gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] Length = 743 Score = 166 bits (419), Expect = 5e-41 Identities = 88/212 (41%), Positives = 119/212 (56%), Gaps = 25/212 (11%) Query: 32 EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91 E + E ++ LE LW +F + EM++TK+GRRMFP K+ +GLD A Y LL+ Sbjct: 94 EPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLM 153 Query: 92 DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151 D + D R+K+ N W+ AGK + +YIHPDSP G WM ++F K+KLTN + Sbjct: 154 DIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNI 213 Query: 152 NG---------------------GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSF 186 + G Q +LNS+HKY+P+ HIVR ++ F Sbjct: 214 SDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLF 273 Query: 187 PETQFIAVTAYQNEEITALKIKYNPFAKAFLD 218 PET+FIAVTAYQN++IT LKI NPFAK F D Sbjct: 274 PETEFIAVTAYQNDKITQLKIDNNPFAKGFRD 305 >gi|158187511 T-box 22 isoform 2 [Homo sapiens] Length = 400 Score = 140 bits (354), Expect = 2e-33 Identities = 75/175 (42%), Positives = 107/175 (61%), Gaps = 20/175 (11%) Query: 70 MFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYV--NGEWVPAGKPEVSSHSCV----Y 123 MFP +++ V GLDP Y + +D VP DS R++YV + +W+ AG + H C+ Y Sbjct: 1 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTD---HLCIIPRFY 57 Query: 124 IHPDSPNFGAHWMKAPISFSKVKLTN-KLNGGGQIMLNSLHKYEPQVHIVRVGSAHRM-- 180 +HPDSP G WM+ ISF ++KLTN +++ G I+L S+HKY+P+VH++ GS+ + Sbjct: 58 VHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQ 117 Query: 181 --------VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLRD 227 V SF ET+F VTAYQN++IT LKI+ NPFAK F D + D Sbjct: 118 IQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLD 172 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 40.0 bits (92), Expect = 0.004 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 29/124 (23%) Query: 339 VPHTNGPINP--------------GPSPYPCLWTISNGAGGPSGP----GPEVHASTPGA 380 +P T GPI P P P + G GP+GP GP H+ PG Sbjct: 447 IPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG- 505 Query: 381 FLLGNPAVTSPPS--------VLSTQAPTSAGVE-VLGEPSLTSIAVSTWTAVASHPFAG 431 L G P PP + + Q P+ +G V +T + VS +T + S + Sbjct: 506 -LPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPA 564 Query: 432 WGGP 435 G P Sbjct: 565 IGTP 568 Score = 31.2 bits (69), Expect = 2.0 Identities = 31/105 (29%), Positives = 35/105 (33%), Gaps = 12/105 (11%) Query: 344 GPINPGPSPYPCLWTISNGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSA 403 GP G P L AG P GPG + G L G P +T PP + Q P Sbjct: 294 GPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAG--LPGKPGLTGPPGNMGPQGPKG- 350 Query: 404 GVEVLGEPSLTSIAVSTWTAVASHPFAGWGGPGAGGHHSPSSLDG 448 + G L T P G PGA G DG Sbjct: 351 ---IPGSHGLPGPKGET------GPAGPAGYPGAKGERGSPGSDG 386 >gi|124378039 SEC16 homolog A [Homo sapiens] Length = 2357 Score = 38.9 bits (89), Expect = 0.010 Identities = 48/163 (29%), Positives = 64/163 (39%), Gaps = 24/163 (14%) Query: 292 PYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGP- 350 P PS + SPSV L+ S+ L GP L+S + VP GP+ PGP Sbjct: 1936 PAPSP---EHSSPSVRLLPSAPQTLP--DGP-----LASPARVPMFPVPLPPGPLEPGPG 1985 Query: 351 --SPYPCLWTISNGAGGPSGPG--PEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVE 406 +P P L G PSGPG P V LL A + P ++ +AP + Sbjct: 1986 CVTPGPAL-----GFLEPSGPGLPPGVPPLQERRHLL-QEARSPDPGIVPQEAPVGNSLS 2039 Query: 407 VLGEPSLT---SIAVSTWTAVASHPFAGWGGPGAGGHHSPSSL 446 L E + + + T S GW +G P SL Sbjct: 2040 ELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSL 2082 >gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] Length = 753 Score = 38.5 bits (88), Expect = 0.012 Identities = 59/224 (26%), Positives = 85/224 (37%), Gaps = 44/224 (19%) Query: 225 LRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPL-PLPAPHTHHGCEHYS 283 L D+P+A+ + ++SH+ IF+ T+ S ++P+ P PA T E Sbjct: 231 LEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTS----SSPIPPSPANCTTENSED-D 285 Query: 284 GLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILS-VPHT 342 RG S +N S V+ S+ + Q + P ++ S P AS LS P Sbjct: 286 KKRGRSTDSEVSQSPAKNGSKPVH----SNQHPQSPAVPPTYPS-GPPPAASALSTTPGN 340 Query: 343 NGPINPGPSPYPCLWTISNGAGGPSGPGPEVHASTPGAFLLGNPAVTSP-PSVLSTQAPT 401 NG P P + G + P P ++ TP + AV P PS ST P Sbjct: 341 NGVPAPAAPP--------SALGPKASPAPSHNSGTPAPYA---QAVAPPAPSGPSTTQPR 389 Query: 402 SAGVEVLGEPSLTSIAVSTWTAVASHPFAGWGGPGAGGHHSPSS 445 V+ G G GG G GG S S+ Sbjct: 390 PPSVQPSG--------------------GGGGGSGGGGSSSSSN 413 >gi|22538422 activating transcription factor 2 [Homo sapiens] Length = 505 Score = 37.4 bits (85), Expect = 0.028 Identities = 43/140 (30%), Positives = 57/140 (40%), Gaps = 16/140 (11%) Query: 269 PLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHS---PSVNLIESSSNNLQVFSGPDSW 325 PLP P + E L Q P++ + R S P+V L S S+ + + P Sbjct: 137 PLPHPESTTSDEKEVPLA---QTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVP--- 190 Query: 326 TSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGPSGPGPEVHAS---TPGAFL 382 S T I P +N PI P P P+P L + NG P + +S P A Sbjct: 191 ---SPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVPAAVP 247 Query: 383 LGNPAVTSPPSVLSTQAPTS 402 L P VT PSV P+S Sbjct: 248 LVRP-VTMVPSVPGIPGPSS 266 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 37.4 bits (85), Expect = 0.028 Identities = 48/201 (23%), Positives = 67/201 (33%), Gaps = 41/201 (20%) Query: 249 SNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHSPSVNL 308 S PD + + ++ PLP P HH H+ H AP P + H H P Sbjct: 974 SPPDTRVGSREKSLYHSGPLP---PAHHHPPHHH-----HHHAPPPQPHHHHAHPPHPPE 1025 Query: 309 IESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPYPCLWTISNGAGGPSG 368 +E+ + PD P ++ P G GPSP P Sbjct: 1026 METGGS-------PD-----DPPPRLALGPQPSLRGWRGGGPSP------------TPGA 1061 Query: 369 PGPEVHASTPGAFLLGNPAVTSPPSVLSTQAPTSAGVEVLGEPSLTSIA----VSTWTAV 424 P P H S G + P++ Q P A + P+ + + T V Sbjct: 1062 PSPSHHGSAG-----GGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKV 1116 Query: 425 ASHPFAGWGGPGAGGHHSPSS 445 P G G P A SP+S Sbjct: 1117 EGEPQKGGGLPPAPSPTSPAS 1137 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.131 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,496,376 Number of Sequences: 37866 Number of extensions: 1223377 Number of successful extensions: 3925 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 49 Number of HSP's successfully gapped in prelim test: 232 Number of HSP's that attempted gapping in prelim test: 3534 Number of HSP's gapped (non-prelim): 576 length of query: 448 length of database: 18,247,518 effective HSP length: 106 effective length of query: 342 effective length of database: 14,233,722 effective search space: 4867932924 effective search space used: 4867932924 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.