BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4826912 paired-like homeodomain 3 [Homo sapiens] (302 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4826912 paired-like homeodomain 3 [Homo sapiens] 616 e-177 gi|24234708 paired-like homeodomain transcription factor 2 isofo... 298 5e-81 gi|21361183 paired-like homeodomain transcription factor 2 isofo... 297 7e-81 gi|24234711 paired-like homeodomain transcription factor 2 isofo... 297 7e-81 gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 280 9e-76 gi|24497589 aristaless related homeobox [Homo sapiens] 126 3e-29 gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 109 3e-24 gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 109 3e-24 gi|4505619 paired box 7 isoform 1 [Homo sapiens] 106 3e-23 gi|7524359 paired box 7 isoform 2 [Homo sapiens] 106 3e-23 gi|207029223 paired box 7 isoform 3 [Homo sapiens] 106 3e-23 gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 104 8e-23 gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 103 2e-22 gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 103 2e-22 gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 102 5e-22 gi|12707580 paired-like homeobox 2b [Homo sapiens] 101 7e-22 gi|46249382 paired-like homeobox 2a [Homo sapiens] 101 9e-22 gi|4557489 cone-rod homeobox protein [Homo sapiens] 100 1e-21 gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 100 2e-21 gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 99 4e-21 gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 99 4e-21 gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 99 4e-21 gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 99 4e-21 gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 99 4e-21 gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 99 4e-21 gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 98 1e-20 gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 98 1e-20 gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 95 7e-20 gi|122937321 UNC homeobox [Homo sapiens] 94 2e-19 gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] 93 3e-19 >gi|4826912 paired-like homeodomain 3 [Homo sapiens] Length = 302 Score = 616 bits (1588), Expect = e-177 Identities = 302/302 (100%), Positives = 302/302 (100%) Query: 1 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKK 60 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKK Sbjct: 1 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKK 60 Query: 61 KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR 120 KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR Sbjct: 61 KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR 120 Query: 121 ERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVG 180 ERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVG Sbjct: 121 ERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVG 180 Query: 181 PLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYA 240 PLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYA Sbjct: 181 PLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYA 240 Query: 241 SAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVER 300 SAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVER Sbjct: 241 SAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVER 300 Query: 301 PV 302 PV Sbjct: 301 PV 302 >gi|24234708 paired-like homeodomain transcription factor 2 isoform b [Homo sapiens] Length = 317 Score = 298 bits (762), Expect = 5e-81 Identities = 169/297 (56%), Positives = 200/297 (67%), Gaps = 25/297 (8%) Query: 10 EARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHF 69 E+R A S HP G D + + G+ ED S KK+QRRQRTHF Sbjct: 42 ESRKEAASSKFFPRQHP--------GANEKDKSQQGKNEDVGA-EDPSKKKRQRRQRTHF 92 Query: 70 TSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELC 129 TSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER+QQAELC Sbjct: 93 TSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELC 152 Query: 130 KGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGPLASQPVF 188 K F GL+ PY+++YPGYSY NW K L + L+ K+FPF FNS+NV PL+SQ +F Sbjct: 153 KNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNPLSSQSMF 211 Query: 189 SPPSSIAASMVPSAAAAPGTVPG-PGALQGLGGGPPGLAPAAVSSG--AVSCPYASAAAA 245 SPP+SI +SM S++ P V G PG+ L+ +++S +CPY Sbjct: 212 SPPNSI-SSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPY------ 264 Query: 246 AAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV 302 A + PYVYRD CNSSLASLRLKAKQH+SF Y +V PA+NLS CQYAV+RPV Sbjct: 265 --APPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN--PASNLSACQYAVDRPV 317 >gi|21361183 paired-like homeodomain transcription factor 2 isoform c [Homo sapiens] Length = 324 Score = 297 bits (761), Expect = 7e-81 Identities = 160/253 (63%), Positives = 187/253 (73%), Gaps = 16/253 (6%) Query: 54 EDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 113 ED S KK+QRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR Sbjct: 84 EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 143 Query: 114 RAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPF 172 RAKWRKRER+QQAELCK F GL+ PY+++YPGYSY NW K L + L+ K+FPF Sbjct: 144 RAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF 203 Query: 173 AFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGALQGLGGGPPGLAPAAVS 231 FNS+NV PL+SQ +FSPP+SI +SM S++ P V G PG+ L+ +++ Sbjct: 204 -FNSMNVNPLSSQSMFSPPNSI-SSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN 261 Query: 232 SG--AVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAA 289 S +CPY A + PYVYRD CNSSLASLRLKAKQH+SF Y +V PA+ Sbjct: 262 SAVPTPACPY--------APPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN--PAS 311 Query: 290 NLSPCQYAVERPV 302 NLS CQYAV+RPV Sbjct: 312 NLSACQYAVDRPV 324 >gi|24234711 paired-like homeodomain transcription factor 2 isoform a [Homo sapiens] Length = 271 Score = 297 bits (761), Expect = 7e-81 Identities = 160/253 (63%), Positives = 187/253 (73%), Gaps = 16/253 (6%) Query: 54 EDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 113 ED S KK+QRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR Sbjct: 31 EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 90 Query: 114 RAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPF 172 RAKWRKRER+QQAELCK F GL+ PY+++YPGYSY NW K L + L+ K+FPF Sbjct: 91 RAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF 150 Query: 173 AFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGALQGLGGGPPGLAPAAVS 231 FNS+NV PL+SQ +FSPP+SI +SM S++ P V G PG+ L+ +++ Sbjct: 151 -FNSMNVNPLSSQSMFSPPNSI-SSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN 208 Query: 232 SG--AVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAA 289 S +CPY A + PYVYRD CNSSLASLRLKAKQH+SF Y +V PA+ Sbjct: 209 SAVPTPACPY--------APPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN--PAS 258 Query: 290 NLSPCQYAVERPV 302 NLS CQYAV+RPV Sbjct: 259 NLSACQYAVDRPV 271 >gi|152963644 paired-like homeodomain transcription factor 1 [Homo sapiens] Length = 314 Score = 280 bits (717), Expect = 9e-76 Identities = 164/299 (54%), Positives = 197/299 (65%), Gaps = 22/299 (7%) Query: 3 FGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQ 62 F L A+ R P L S + + +LPE G+ + + G +D + KKKQ Sbjct: 31 FHLARPADPREP-LENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQ 89 Query: 63 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 122 RRQRTHFTSQQLQELEATFQRNRYPDMS REEIAVWTNLTE RVRVWFKNRRAKWRKRER Sbjct: 90 RRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149 Query: 123 SQQAELCKGSFAAPLGGLVPPYEEVY-PGYSYGNWPPKALAP-PLAAKTFPFAFNSVNVG 180 +QQ +LCKG + GLV PYE+VY GYSY NW K+LAP PL+ K+F F FNS++ Sbjct: 150 NQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTF-FNSMS-- 206 Query: 181 PLASQPVFSPPSSIAASMVPSAAAAPGTVPG--PGALQGLGGGPPGLAPAAVSSGAVSCP 238 PL+SQ +FS PSSI++ +PS + PG VPG L + +A+S GA CP Sbjct: 207 PLSSQSMFSAPSSISSMTMPS-SMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGA--CP 263 Query: 239 YASAAAAAAAAASSPY-VYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQY 296 Y + A SPY VYRD CNSSLASLRLK+KQH+SF Y + G PA+ L+ CQY Sbjct: 264 YGTPA--------SPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQG--PASGLNACQY 312 >gi|24497589 aristaless related homeobox [Homo sapiens] Length = 562 Score = 126 bits (316), Expect = 3e-29 Identities = 96/260 (36%), Positives = 125/260 (48%), Gaps = 38/260 (14%) Query: 37 EHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIA 96 E D E + G E+G LK+KQRR RT FTS QL+ELE FQ+ YPD+ TREE+A Sbjct: 303 EGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELA 362 Query: 97 VWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNW 156 + +LTEARV+VWF+NRRAKWRKRE++ G P +PG Sbjct: 363 MRLDLTEARVQVWFQNRRAKWRKREKA--------------GAQTHPPGLPFPGPLSATH 408 Query: 157 PPKALAPPLAAKTFP-------FAFNSVNVGPLASQPVFSPPSSIAASMVPSAA-AAPGT 208 P L+P L A FP A+ + A+ P PP +AS+ PS A T Sbjct: 409 P---LSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPG-SASLPPSGAPLGLST 464 Query: 209 VPGPGALQGLGGGPPG-------LAPAAVSSGAVS-----CPYASAAAAAAAAASSPYVY 256 G + P +AP +S A + P A A+ A A Sbjct: 465 FLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAA 524 Query: 257 RDPCNSSLASLRLKAKQHAS 276 D SS+A+LRLKAK+HA+ Sbjct: 525 ADRRASSIAALRLKAKEHAA 544 Score = 29.6 bits (65), Expect = 3.4 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 5/60 (8%) Query: 192 SSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAAS 251 ++ AA+ +AAAA GP G PP P A A+AAAAAAAAA+ Sbjct: 101 AAAAAAAAAAAAAAATATAGPR-----GEAPPPPPPTARPGERPDGAGAAAAAAAAAAAA 155 >gi|126116581 retina and anterior neural fold homeobox [Homo sapiens] Length = 346 Score = 109 bits (273), Expect = 3e-24 Identities = 97/280 (34%), Positives = 123/280 (43%), Gaps = 38/280 (13%) Query: 10 EARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSP-------EDGSLKKKQ 62 E P+ + A P + P C + + S LP G E+ KKK Sbjct: 79 EGSEPSPPPAPAPAPEYEAPRPYCP--KEPGEARPSPGLPVGPATGEAKLSEEEQPKKKH 136 Query: 63 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRE- 121 RR RT FT+ QL ELE F+++ YPD+ +REE+A NL E RV+VWF+NRRAKWR++E Sbjct: 137 RRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK 196 Query: 122 ------RSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFN 175 + Q + L S + P L P PG G P A PL + P Sbjct: 197 LEVSSMKLQDSPLLSFSRSPPSATLSP--LGAGPGSGGG---PAGGALPLESWLGP-PLP 250 Query: 176 SVNVGPLASQPVFSPPS-SIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGA 234 L S P F PP+ S+ AS P P P LG G LAP Sbjct: 251 GGGATALQSLPGFGPPAQSLPASYTPPPPPPPFLNSPP-----LGPGLQPLAP------- 298 Query: 235 VSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQH 274 P S P DP NSS+A+LRLKAK+H Sbjct: 299 ---PPPSYPCGPGFGDKFPLDEADPRNSSIAALRLKAKEH 335 >gi|55743092 aristaless-like homeobox 4 [Homo sapiens] Length = 411 Score = 109 bits (273), Expect = 3e-24 Identities = 89/270 (32%), Positives = 123/270 (45%), Gaps = 47/270 (17%) Query: 13 SPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGG--SPEDGSLKKKQRRQRTHFT 70 S LS+ +AG PQ ++AS+ LP + S K K+RR RT FT Sbjct: 177 SSYLSVKEAGVKGPQ--------------DRASSDLPSPLEKADSESNKGKKRRNRTTFT 222 Query: 71 SQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCK 130 S QL+ELE FQ+ YPD+ RE++A+ T+LTEARV+VWF+NRRAKWRKRER Q + + Sbjct: 223 SYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVR 282 Query: 131 GSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSP 190 F+ + E Y +W L AA P + P P P Sbjct: 283 THFSTAYELPLLTRAENYAQIQNPSW----LGNNGAASPVPACVVPCDPVPACMSPHAHP 338 Query: 191 PSSIAASMVP----SAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAA 246 P S A+S+ S A + G+L G PGL ++ Sbjct: 339 PGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNGEP------------ 386 Query: 247 AAAASSPYVYRDPCNSSLASLRLKAKQHAS 276 D SS+A+LR+KAK+H++ Sbjct: 387 -----------DRKTSSIAALRMKAKEHSA 405 >gi|4505619 paired box 7 isoform 1 [Homo sapiens] Length = 520 Score = 106 bits (264), Expect = 3e-23 Identities = 69/167 (41%), Positives = 90/167 (53%), Gaps = 23/167 (13%) Query: 52 SPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFK 111 S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEARV+VWF Sbjct: 207 SEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFS 266 Query: 112 NRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL--APP--LAA 167 NRRA+WRK+ + Q A L+P G +PP + PP L Sbjct: 267 NRRARWRKQAGANQ--------LAAFNHLLP-----------GGFPPTGMPTLPPYQLPD 307 Query: 168 KTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGA 214 T+P S + G +P PPS++ + +AAAA T GA Sbjct: 308 STYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGA 354 >gi|7524359 paired box 7 isoform 2 [Homo sapiens] Length = 518 Score = 106 bits (264), Expect = 3e-23 Identities = 69/167 (41%), Positives = 90/167 (53%), Gaps = 23/167 (13%) Query: 52 SPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFK 111 S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEARV+VWF Sbjct: 205 SEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFS 264 Query: 112 NRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL--APP--LAA 167 NRRA+WRK+ + Q A L+P G +PP + PP L Sbjct: 265 NRRARWRKQAGANQ--------LAAFNHLLP-----------GGFPPTGMPTLPPYQLPD 305 Query: 168 KTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGA 214 T+P S + G +P PPS++ + +AAAA T GA Sbjct: 306 STYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGA 352 >gi|207029223 paired box 7 isoform 3 [Homo sapiens] Length = 505 Score = 106 bits (264), Expect = 3e-23 Identities = 69/167 (41%), Positives = 90/167 (53%), Gaps = 23/167 (13%) Query: 52 SPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFK 111 S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEARV+VWF Sbjct: 207 SEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFS 266 Query: 112 NRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL--APP--LAA 167 NRRA+WRK+ + Q A L+P G +PP + PP L Sbjct: 267 NRRARWRKQAGANQ--------LAAFNHLLP-----------GGFPPTGMPTLPPYQLPD 307 Query: 168 KTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGA 214 T+P S + G +P PPS++ + +AAAA T GA Sbjct: 308 STYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGA 354 >gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] Length = 326 Score = 104 bits (260), Expect = 8e-23 Identities = 56/119 (47%), Positives = 68/119 (57%) Query: 42 EKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNL 101 EK G + K+RR RT FTS QL+ELE FQ+ YPD+ RE++A+ T L Sbjct: 112 EKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTEL 171 Query: 102 TEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKA 160 TEARV+VWF+NRRAKWRKRER Q + K FAA V P + YP W A Sbjct: 172 TEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNA 230 >gi|113204604 aristaless-like homeobox 3 [Homo sapiens] Length = 343 Score = 103 bits (256), Expect = 2e-22 Identities = 80/236 (33%), Positives = 111/236 (47%), Gaps = 37/236 (15%) Query: 44 ASASLP--GGSPEDGSL---KKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW 98 AS LP G P+ L K K+RR RT F++ QL+ELE FQ+ YPD+ RE++A+ Sbjct: 130 ASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALR 189 Query: 99 TNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPP 158 T+LTEARV+VWF+NRRAKWRKRER + + + F A V P + +P W Sbjct: 190 TDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWAS 249 Query: 159 KALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGL 218 P P ++ +PS +P + P G++ G Sbjct: 250 PGSGSP------------------------GGPCLVSPEGIPSPCMSPYSHP-HGSVAGF 284 Query: 219 GGGPPGLAPAAVSSGAVSC-PYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQ 273 G P AP+A G S + + SS Y+ P SL SLR+K K+ Sbjct: 285 MGVP---APSAAHPGIYSIHGFPPTLGGHSFEPSSDGDYKSP---SLVSLRVKPKE 334 >gi|20070107 orthodenticle homeobox 1 [Homo sapiens] Length = 354 Score = 103 bits (256), Expect = 2e-22 Identities = 74/202 (36%), Positives = 103/202 (50%), Gaps = 26/202 (12%) Query: 60 KKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRK 119 +KQRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+RV+VWFKNRRAK R+ Sbjct: 36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95 Query: 120 RERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNV 179 +++S G+ + P P E S G + P A++ +S + Sbjct: 96 QQQSG-----SGTKSRPAKKKSSPVRESSGSESSGQFTPPAVS------------SSASS 138 Query: 180 GPLASQPVFSPPSSIAASM--VPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVS------ 231 AS +P ++ AA + P AAA+ + P ++ PG APA+VS Sbjct: 139 SSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLA 198 Query: 232 -SGAVSCPYASAAAAAAAAASS 252 SC S AA AA AA+S Sbjct: 199 APSNTSCMQRSVAAGAATAAAS 220 >gi|122937484 dorsal root ganglia homeobox [Homo sapiens] Length = 268 Score = 102 bits (253), Expect = 5e-22 Identities = 78/225 (34%), Positives = 111/225 (49%), Gaps = 29/225 (12%) Query: 51 GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWF 110 G +DG L++KQRR RT FT QQL+ LEA F + YPD+ TREE+A+ NLTEARV+VWF Sbjct: 27 GDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWF 86 Query: 111 KNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTF 170 +NRRAKWRK ER + + P+ + PP P + + PP A Sbjct: 87 QNRRAKWRKTERGASDQ--EPGAKEPMAEVTPP-----PVRNINSPPPGDQARSKKEALE 139 Query: 171 PFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAV 230 VGP + P F PS + +++ +A A + L GGP + Sbjct: 140 AQQSLGRTVGP--AGPFF--PSCLPGTLLNTATYAQAL----SHVASLKGGP-------L 184 Query: 231 SSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHA 275 S V P + S+ +S+A+LR+KA++H+ Sbjct: 185 CSCCVPDPMGLSFLPTYGCQSNR-------TASVATLRMKAREHS 222 >gi|12707580 paired-like homeobox 2b [Homo sapiens] Length = 314 Score = 101 bits (252), Expect = 7e-22 Identities = 80/198 (40%), Positives = 100/198 (50%), Gaps = 26/198 (13%) Query: 59 KKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWR 118 K+KQRR RT FTS QL+ELE F YPD+ TREE+A+ +LTEARV+VWF+NRRAK+R Sbjct: 95 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 154 Query: 119 KRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVN 178 K+ER+ A + AA G + S A T P + Sbjct: 155 KQERAAAA----AAAAAKNGSSGKKSDSSRDDES-----------KEAKSTDPDSTGGPG 199 Query: 179 VGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCP 238 P P S ++ PS A APG GPG GG PG AA ++ A + Sbjct: 200 PNP---NPTPSCGANGGGGGGPSPAGAPGAA-GPGG----PGGEPGKGGAAAAAAAAAAA 251 Query: 239 YASAAAAAA---AAASSP 253 A+AAAAAA AAA P Sbjct: 252 AAAAAAAAAGGLAAAGGP 269 >gi|46249382 paired-like homeobox 2a [Homo sapiens] Length = 284 Score = 101 bits (251), Expect = 9e-22 Identities = 83/218 (38%), Positives = 104/218 (47%), Gaps = 24/218 (11%) Query: 21 AGTPHPQLPEHGCKGQEHSDSEKASASLPGGS--PEDGSL--KKKQRRQRTHFTSQQLQE 76 AG P P L C D + A S PE L K+KQRR RT FTS QL+E Sbjct: 45 AGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKE 104 Query: 77 LEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAP 136 LE F YPD+ TREE+A+ +LTEARV+VWF+NRRAK+RK+ER+ A+ G+ A Sbjct: 105 LERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAK 164 Query: 137 LGGLVPPYEEVYPGYSYGNWPPKALA--PPLAAKTFPFAFNSVNVGPLASQPVFSPPSSI 194 G E+ S + P + A PP A P + P S PS + Sbjct: 165 KGEARCSSEDDDSKESTCSPTPDSTASLPPPPA-------------PGLASPRLS-PSPL 210 Query: 195 AASMVPSAAAAPGTVPGPGAL----QGLGGGPPGLAPA 228 ++ PG P GAL G GGG PG A Sbjct: 211 PVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAA 248 >gi|4557489 cone-rod homeobox protein [Homo sapiens] Length = 299 Score = 100 bits (250), Expect = 1e-21 Identities = 75/205 (36%), Positives = 97/205 (47%), Gaps = 29/205 (14%) Query: 57 SLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 116 S +KQRR+RT FT QL+ELEA F + +YPD+ REE+A+ NL E+RV+VWFKNRRAK Sbjct: 34 SAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAK 93 Query: 117 WRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNS 176 R++ + Q+ + P GG KA A T P Sbjct: 94 CRQQRQQQKQQ------QQPPGG-----------------QAKARPAKRKAGTSPRPSTD 130 Query: 177 VNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSG--A 234 V PL +SPP S P+ A A ++ P + L P V+SG Sbjct: 131 VCPDPLGISDSYSPPLP-GPSGSPTTAVATVSIWSPASESPL---PEAQRAGLVASGPSL 186 Query: 235 VSCPYASAAAAAAAAASSPYVYRDP 259 S PYA A A+A SSP Y P Sbjct: 187 TSAPYAMTYAPASAFCSSPSAYGSP 211 >gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] Length = 331 Score = 100 bits (248), Expect = 2e-21 Identities = 86/234 (36%), Positives = 113/234 (48%), Gaps = 43/234 (18%) Query: 51 GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWF 110 G ++G K KQRR RT+FT +QL ELE F YPD REE++ L+EARV+VWF Sbjct: 129 GMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWF 188 Query: 111 KNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTF 170 +NRRAK RK+E + G+ + V PY V A Sbjct: 189 QNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNV------------------GALRM 230 Query: 171 PFAFNS-VNVGPLASQ--PVFSPPSSIAAS---MVPSAAA-APGTV-PGPGALQGLGGGP 222 PF +S NV PL+ Q S++A + + P AA AP + P P P Sbjct: 231 PFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAP---------P 281 Query: 223 PGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHAS 276 GL A +++ + S AAAAAA S NSS+A LRLKAK+HA+ Sbjct: 282 FGLPLATLAADSASAASVVAAAAAAKTTSK--------NSSIADLRLKAKKHAA 327 >gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] Length = 483 Score = 99.4 bits (246), Expect = 4e-21 Identities = 71/205 (34%), Positives = 98/205 (47%), Gaps = 25/205 (12%) Query: 41 SEKASASLPG-----GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI 95 SE+ASA S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+ Sbjct: 192 SERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREEL 251 Query: 96 AVWTNLTEARVRVWFKNRRAKWRKRERSQQA----ELCKGSFAAPLGGLVPPYEEVYPGY 151 A LTEARV+VWF NRRA+WRK+ + Q L G F +P Y+ Y Sbjct: 252 AQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSY 311 Query: 152 SYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG 211 + P+A++ P + P QP+ PPS++ S +PS + Sbjct: 312 QPTS-IPQAVSDPSSTVHRP-------------QPL--PPSTVHQSTIPSNPDSSSAYCL 355 Query: 212 PGALQGLGGGPPGLAPAAVSSGAVS 236 P G P + S ++ Sbjct: 356 PSTRHGFSSYTDSFVPPSGPSNPMN 380 >gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] Length = 403 Score = 99.4 bits (246), Expect = 4e-21 Identities = 71/205 (34%), Positives = 98/205 (47%), Gaps = 25/205 (12%) Query: 41 SEKASASLPG-----GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI 95 SE+ASA S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+ Sbjct: 193 SERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREEL 252 Query: 96 AVWTNLTEARVRVWFKNRRAKWRKRERSQQA----ELCKGSFAAPLGGLVPPYEEVYPGY 151 A LTEARV+VWF NRRA+WRK+ + Q L G F +P Y+ Y Sbjct: 253 AQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSY 312 Query: 152 SYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG 211 + P+A++ P + P QP+ PPS++ S +PS + Sbjct: 313 QPTS-IPQAVSDPSSTVHRP-------------QPL--PPSTVHQSTIPSNPDSSSAYCL 356 Query: 212 PGALQGLGGGPPGLAPAAVSSGAVS 236 P G P + S ++ Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMN 381 >gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] Length = 407 Score = 99.4 bits (246), Expect = 4e-21 Identities = 71/205 (34%), Positives = 98/205 (47%), Gaps = 25/205 (12%) Query: 41 SEKASASLPG-----GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI 95 SE+ASA S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+ Sbjct: 193 SERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREEL 252 Query: 96 AVWTNLTEARVRVWFKNRRAKWRKRERSQQA----ELCKGSFAAPLGGLVPPYEEVYPGY 151 A LTEARV+VWF NRRA+WRK+ + Q L G F +P Y+ Y Sbjct: 253 AQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSY 312 Query: 152 SYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG 211 + P+A++ P + P QP+ PPS++ S +PS + Sbjct: 313 QPTS-IPQAVSDPSSTVHRP-------------QPL--PPSTVHQSTIPSNPDSSSAYCL 356 Query: 212 PGALQGLGGGPPGLAPAAVSSGAVS 236 P G P + S ++ Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMN 381 >gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] Length = 505 Score = 99.4 bits (246), Expect = 4e-21 Identities = 71/205 (34%), Positives = 98/205 (47%), Gaps = 25/205 (12%) Query: 41 SEKASASLPG-----GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI 95 SE+ASA S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+ Sbjct: 193 SERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREEL 252 Query: 96 AVWTNLTEARVRVWFKNRRAKWRKRERSQQA----ELCKGSFAAPLGGLVPPYEEVYPGY 151 A LTEARV+VWF NRRA+WRK+ + Q L G F +P Y+ Y Sbjct: 253 AQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSY 312 Query: 152 SYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG 211 + P+A++ P + P QP+ PPS++ S +PS + Sbjct: 313 QPTS-IPQAVSDPSSTVHRP-------------QPL--PPSTVHQSTIPSNPDSSSAYCL 356 Query: 212 PGALQGLGGGPPGLAPAAVSSGAVS 236 P G P + S ++ Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMN 381 >gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] Length = 484 Score = 99.4 bits (246), Expect = 4e-21 Identities = 71/205 (34%), Positives = 98/205 (47%), Gaps = 25/205 (12%) Query: 41 SEKASASLPG-----GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI 95 SE+ASA S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+ Sbjct: 193 SERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREEL 252 Query: 96 AVWTNLTEARVRVWFKNRRAKWRKRERSQQA----ELCKGSFAAPLGGLVPPYEEVYPGY 151 A LTEARV+VWF NRRA+WRK+ + Q L G F +P Y+ Y Sbjct: 253 AQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSY 312 Query: 152 SYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG 211 + P+A++ P + P QP+ PPS++ S +PS + Sbjct: 313 QPTS-IPQAVSDPSSTVHRP-------------QPL--PPSTVHQSTIPSNPDSSSAYCL 356 Query: 212 PGALQGLGGGPPGLAPAAVSSGAVS 236 P G P + S ++ Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMN 381 >gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] Length = 479 Score = 99.4 bits (246), Expect = 4e-21 Identities = 71/205 (34%), Positives = 98/205 (47%), Gaps = 25/205 (12%) Query: 41 SEKASASLPG-----GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI 95 SE+ASA S D LK+KQRR RT FT++QL+ELE F+R YPD+ TREE+ Sbjct: 193 SERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREEL 252 Query: 96 AVWTNLTEARVRVWFKNRRAKWRKRERSQQA----ELCKGSFAAPLGGLVPPYEEVYPGY 151 A LTEARV+VWF NRRA+WRK+ + Q L G F +P Y+ Y Sbjct: 253 AQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSY 312 Query: 152 SYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG 211 + P+A++ P + P QP+ PPS++ S +PS + Sbjct: 313 QPTS-IPQAVSDPSSTVHRP-------------QPL--PPSTVHQSTIPSNPDSSSAYCL 356 Query: 212 PGALQGLGGGPPGLAPAAVSSGAVS 236 P G P + S ++ Sbjct: 357 PSTRHGFSSYTDSFVPPSGPSNPMN 381 >gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo sapiens] Length = 382 Score = 97.8 bits (242), Expect = 1e-20 Identities = 84/246 (34%), Positives = 115/246 (46%), Gaps = 27/246 (10%) Query: 56 GSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 115 GS +KQRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRA Sbjct: 65 GSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRA 124 Query: 116 KWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL--APPLAAKTFPFA 173 K+RK++RS Q E + A E P P L + P A + Sbjct: 125 KFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLS 184 Query: 174 FNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLG---GGPPGLAPAAV 230 S + QP A + P A +PG +GLG G P +P ++ Sbjct: 185 EQSASESAPEDQP-DREEDPRAGAEDPKAEKSPG-----ADSKGLGCKRGSPKADSPGSL 238 Query: 231 SSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVH------- 283 + V+ P + + +SSP SL L+ + +QH + + VH Sbjct: 239 TITPVA-PGGGLLGPSHSYSSSPL--------SLFRLQEQFRQHMAATNNLVHYSSFEVG 289 Query: 284 GPPPAA 289 GP PAA Sbjct: 290 GPAPAA 295 Score = 32.7 bits (73), Expect = 0.40 Identities = 40/124 (32%), Positives = 52/124 (41%), Gaps = 33/124 (26%) Query: 153 YGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGP 212 Y ++ AP AA + VN+ PL S S S+ SAAAA Sbjct: 283 YSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSL------SAAAA------- 329 Query: 213 GALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAK 272 A QG+ G P L PA P A A A+A S +S+ +LRL+AK Sbjct: 330 -AHQGVWGSP--LLPA---------PPAGLAPASATLNSK--------TTSIENLRLRAK 369 Query: 273 QHAS 276 QHA+ Sbjct: 370 QHAA 373 >gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo sapiens] Length = 377 Score = 97.8 bits (242), Expect = 1e-20 Identities = 84/246 (34%), Positives = 115/246 (46%), Gaps = 27/246 (10%) Query: 56 GSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 115 GS +KQRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRA Sbjct: 60 GSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRA 119 Query: 116 KWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL--APPLAAKTFPFA 173 K+RK++RS Q E + A E P P L + P A + Sbjct: 120 KFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLS 179 Query: 174 FNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLG---GGPPGLAPAAV 230 S + QP A + P A +PG +GLG G P +P ++ Sbjct: 180 EQSASESAPEDQP-DREEDPRAGAEDPKAEKSPG-----ADSKGLGCKRGSPKADSPGSL 233 Query: 231 SSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVH------- 283 + V+ P + + +SSP SL L+ + +QH + + VH Sbjct: 234 TITPVA-PGGGLLGPSHSYSSSPL--------SLFRLQEQFRQHMAATNNLVHYSSFEVG 284 Query: 284 GPPPAA 289 GP PAA Sbjct: 285 GPAPAA 290 Score = 32.7 bits (73), Expect = 0.40 Identities = 40/124 (32%), Positives = 52/124 (41%), Gaps = 33/124 (26%) Query: 153 YGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGP 212 Y ++ AP AA + VN+ PL S S S+ SAAAA Sbjct: 278 YSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSL------SAAAA------- 324 Query: 213 GALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAK 272 A QG+ G P L PA P A A A+A S +S+ +LRL+AK Sbjct: 325 -AHQGVWGSP--LLPA---------PPAGLAPASATLNSK--------TTSIENLRLRAK 364 Query: 273 QHAS 276 QHA+ Sbjct: 365 QHAA 368 >gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] Length = 292 Score = 95.1 bits (235), Expect = 7e-20 Identities = 95/307 (30%), Positives = 127/307 (41%), Gaps = 90/307 (29%) Query: 1 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEK----ASASLPGG----- 51 +E GL E + SL D P H K +D EK +A + G Sbjct: 39 LESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECK 98 Query: 52 --------SPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTE 103 EDG K KQRR RT+FT +QL ELE F YPD REE++ L+E Sbjct: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158 Query: 104 ARVRVWFKNRRAKWRKRER----------SQQAELCKGSFAAPLGGLVPPYEEV-----Y 148 ARV+VWF+NRRAK RK+E + + C+ + +G L P+++V Sbjct: 159 ARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQL 218 Query: 149 PGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGT 208 G ++ + L P LAA A +F PP Sbjct: 219 EGVAHAH---PHLHPHLAAH--------------APYLMFPPP----------------- 244 Query: 209 VPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLR 268 P GL A+++ ASAAA AAAA S + NSS+A LR Sbjct: 245 -------------PFGLPIASLAES------ASAAAVVAAAAKS-----NSKNSSIADLR 280 Query: 269 LKAKQHA 275 LKA++HA Sbjct: 281 LKARKHA 287 >gi|122937321 UNC homeobox [Homo sapiens] Length = 531 Score = 93.6 bits (231), Expect = 2e-19 Identities = 82/265 (30%), Positives = 112/265 (42%), Gaps = 52/265 (19%) Query: 51 GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWF 110 G P+ S K+RR RT+FT QL+ELE F + YPD+ RE +A+ +L E+RV+VWF Sbjct: 94 GDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWF 153 Query: 111 KNRRAKWRKRERSQQA----------ELCKGSFAAP------------------------ 136 +NRRAKWRK+E +++ C G P Sbjct: 154 QNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLK 213 Query: 137 --------LGGL----VPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLAS 184 GGL P + G PP+ PP AAK P A S G + Sbjct: 214 SQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPE--PPPPAAKG-PGAHASGAAGTAPA 270 Query: 185 QPVFSP-PSSIAASMVPSAAAAPGTVPGPG--ALQGLGGGPPGLAPAAVSSGAVSCPYAS 241 P P P + + PS + G P PG A + PG A AAV GA P AS Sbjct: 271 PPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKAS 330 Query: 242 AAAAAAAAASSPYVYRDPCNSSLAS 266 + + + SP + N++ A+ Sbjct: 331 PFSVESLLSDSPPRRKAASNAAAAA 355 >gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] Length = 190 Score = 93.2 bits (230), Expect = 3e-19 Identities = 78/236 (33%), Positives = 103/236 (43%), Gaps = 65/236 (27%) Query: 54 EDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 113 ++G K KQRR RT+FT +QL ELE F YPD REE++ L+EARV+VWF+NR Sbjct: 3 DEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNR 62 Query: 114 RAKWRKRER----------SQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKA--- 160 RAK RK+E + Q E C+ + +G L P+++V + A Sbjct: 63 RAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQVQAQLQLDSAVAHAHHH 122 Query: 161 LAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGG 220 L P LAA F P P Sbjct: 123 LHPHLAAHAPYMMF-----------------------------------PAP-------- 139 Query: 221 GPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHAS 276 P GL A +++ + S AAAAAA S NSS+A LRLKAK+HA+ Sbjct: 140 -PFGLPLATLAADSASAASVVAAAAAAKTTSK--------NSSIADLRLKAKKHAA 186 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,653,891 Number of Sequences: 37866 Number of extensions: 805098 Number of successful extensions: 8092 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 431 Number of HSP's successfully gapped in prelim test: 577 Number of HSP's that attempted gapping in prelim test: 5158 Number of HSP's gapped (non-prelim): 2549 length of query: 302 length of database: 18,247,518 effective HSP length: 102 effective length of query: 200 effective length of database: 14,385,186 effective search space: 2877037200 effective search space used: 2877037200 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.