Search of human proteins with 4826816

Search of human proteins with 4826816

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826816 leucine-rich, glioma inactivated 1 precursor [Homo
sapiens]
         (557 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826816 leucine-rich, glioma inactivated 1 precursor [Homo sa...  1138   0.0  
gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens]   632   0.0  
gi|21281681 leucine-rich repeat LGI family, member 3 [Homo sapiens]   609   e-174
gi|21281673 leucine-rich repeat LGI family, member 4 [Homo sapiens]   520   e-147
gi|11321571 slit homolog 3 [Homo sapiens]                              98   2e-20
gi|188528675 slit homolog 1 [Homo sapiens]                             96   7e-20
gi|4759146 slit homolog 2 [Homo sapiens]                               95   1e-19
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   94   4e-19
gi|109150416 peroxidasin [Homo sapiens]                                87   5e-17
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]    87   5e-17
gi|40217825 slit and trk like 6 [Homo sapiens]                         86   7e-17
gi|15029530 leucine rich repeat containing 4 [Homo sapiens]            86   9e-17
gi|54607118 leucine-rich repeats and immunoglobulin-like domains...    83   6e-16
gi|59823631 G protein-coupled receptor 125 [Homo sapiens]              83   6e-16
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ...    83   6e-16
gi|51317373 netrin-G1 ligand [Homo sapiens]                            83   8e-16
gi|88702793 slit-like 2 [Homo sapiens]                                 83   8e-16
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...    82   1e-15
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...    82   1e-15
gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]        82   2e-15
gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]         82   2e-15
gi|194272183 G protein-coupled receptor 124 [Homo sapiens]             82   2e-15
gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]                 82   2e-15

>gi|4826816 leucine-rich, glioma inactivated 1 precursor [Homo
           sapiens]
          Length = 557

 Score = 1138 bits (2944), Expect = 0.0
 Identities = 557/557 (100%), Positives = 557/557 (100%)

Query: 1   MESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARS 60
           MESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARS
Sbjct: 1   MESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARS 60

Query: 61  IPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYL 120
           IPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYL
Sbjct: 61  IPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYL 120

Query: 121 FIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCK 180
           FIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCK
Sbjct: 121 FIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCK 180

Query: 181 LKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQDLPYQSLSID 240
           LKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQDLPYQSLSID
Sbjct: 181 LKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQDLPYQSLSID 240

Query: 241 TFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIETQLYVIVA 300
           TFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIETQLYVIVA
Sbjct: 241 TFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIETQLYVIVA 300

Query: 301 QLFGGSHIYKRDSFANKFIKIQDIEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIY 360
           QLFGGSHIYKRDSFANKFIKIQDIEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIY
Sbjct: 301 QLFGGSHIYKRDSFANKFIKIQDIEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIY 360

Query: 361 KWNGNGFYSHQSLHAWYRDTDVEYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQLF 420
           KWNGNGFYSHQSLHAWYRDTDVEYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQLF
Sbjct: 361 KWNGNGFYSHQSLHAWYRDTDVEYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQLF 420

Query: 421 TNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQ 480
           TNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQ
Sbjct: 421 TNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQ 480

Query: 481 PLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASS 540
           PLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASS
Sbjct: 481 PLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASS 540

Query: 541 FKGNTQIYKHVIVDLSA 557
           FKGNTQIYKHVIVDLSA
Sbjct: 541 FKGNTQIYKHVIVDLSA 557


>gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens]
          Length = 545

 Score =  632 bits (1629), Expect = 0.0
 Identities = 297/516 (57%), Positives = 381/516 (73%), Gaps = 6/516 (1%)

Query: 41  KCPAVCTCTKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTS 100
           +CPA C+CTK++ +C  +  +PR VP D+ SLS V   F+EI +  F   PSLQLLL  S
Sbjct: 35  RCPATCSCTKESIICVGSSWVPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNS 94

Query: 101 NSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFK 160
           NSF +I DDAF GL HLEYLFIE N I++ISR+ FRGL+ L HLSLANN+++ LP+D+F 
Sbjct: 95  NSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFS 154

Query: 161 GLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFD 220
            LDSL  +DLRGN F CDCK KWL  WL  TN+TV D+ C GPPEY+++K+N ++S D++
Sbjct: 155 DLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVTSFDYE 214

Query: 221 CIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITG 280
           C  T+F   Q LPYQS+S+DTF+  ND YV IAQP    C+ LEWDH+E  FR+YDNITG
Sbjct: 215 CTTTDFVVHQTLPYQSVSVDTFNSKNDVYVAIAQPSMENCMVLEWDHIEMNFRSYDNITG 274

Query: 281 TSTVVCKPIVIETQLYVIVAQLFGGSHIYKRDSFANKFIKIQDIEILKIRKPNDIETFKI 340
            S V CK I+I+ Q++V+VAQLFGGSHIYK D    KF+K QDIE+ +I KPNDIE F+I
Sbjct: 275 QSIVGCKAILIDDQVFVVVAQLFGGSHIYKYDESWTKFVKFQDIEVSRISKPNDIELFQI 334

Query: 341 ENNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIVRTPQTLRTPHLI 400
           ++  +FV+ADSSKAG +T+YKWN  GFYS+QSLH W+RDTD E+++I          HLI
Sbjct: 335 DDETFFVIADSSKAGLSTVYKWNSKGFYSYQSLHEWFRDTDAEFVDID------GKSHLI 388

Query: 401 LSSSSQRPVIYQWNKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKW 460
           LSS SQ P+I QWNK+++ F    DIPNMEDV AVK F ++  +Y+ LTRFIGDS+VM+W
Sbjct: 389 LSSRSQVPIILQWNKSSKKFVPHGDIPNMEDVLAVKSFRMQNTLYLSLTRFIGDSRVMRW 448

Query: 461 GGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQ 520
               F +IQ +PSRG+M  QP    +  Y  LGSDY+F+Q+Y WD EK  F KF+E+ VQ
Sbjct: 449 NSKQFVEIQALPSRGAMTLQPFSFKDNHYLALGSDYTFSQIYQWDKEKQLFKKFKEIYVQ 508

Query: 521 APRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLS 556
           APRSFT VS ++R+F FASSFKG T+I++H+IVDLS
Sbjct: 509 APRSFTAVSTDRRDFFFASSFKGKTKIFEHIIVDLS 544


>gi|21281681 leucine-rich repeat LGI family, member 3 [Homo sapiens]
          Length = 548

 Score =  609 bits (1570), Expect = e-174
 Identities = 278/530 (52%), Positives = 381/530 (71%), Gaps = 7/530 (1%)

Query: 29  LLLTEGKKPAK-PKCPAVCTCTKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSF 87
           +L    K+P K P CP  C+CT+D A C +++++PR +P +VISL+ V + F+EI +G+F
Sbjct: 25  MLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAF 84

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
              P LQ LL  SN F +I D+AF GL HL+YLFIENN+I ++S+ TFRGLKSL HLSLA
Sbjct: 85  SHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLA 144

Query: 148 NNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYK 207
           NNNLQTLP+DIF+ LD L ++DLRGNS NCDCK+KWLVEWL HTN TV  IYC  PP ++
Sbjct: 145 NNNLQTLPRDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQ 204

Query: 208 KRKINSLSSKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDH 267
           + K+  L  ++FDCI T+F   Q L + ++S + F Y +D Y+ +AQP    C  L+WD+
Sbjct: 205 EHKVQDLPLREFDCITTDFVLYQTLAFPAVSAEPFLYSSDLYLALAQPGVSACTILKWDY 264

Query: 268 VEKTFRNYDNITGTSTVVCKPIVIETQLYVIVAQLFGGSHIYKRDSFANKFIKIQDIEIL 327
           VE+  R+YD I   S V CKP+V+++QLYV+VAQLFGGS+IY  D    +F ++QDI+  
Sbjct: 265 VERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTRLQDIDPQ 324

Query: 328 KIRKPNDIETFKIENNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEI 387
           ++RKPND+E F+I+ +WYF VADSSKAG T++Y+W+ NGFYSHQ+LH W+RDTD+E+++ 
Sbjct: 325 RVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVD- 383

Query: 388 VRTPQTLRTPHLILSSSSQRPVIYQWNKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYIC 447
                    P LI+SSSSQ PVIYQW++  + F  Q ++  + D  AVKHF    D Y+C
Sbjct: 384 -----GEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLC 438

Query: 448 LTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAE 507
           L+R+IGDSK+++W G+ F ++Q +PSRGS+  QP  +   +Y  LGSD+SFTQ+Y WD  
Sbjct: 439 LSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEG 498

Query: 508 KAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA 557
           + KFV+FQEL VQAPR+F ++       L A SFKG T +Y+H++VDLSA
Sbjct: 499 RQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHIVVDLSA 548


>gi|21281673 leucine-rich repeat LGI family, member 4 [Homo sapiens]
          Length = 537

 Score =  520 bits (1340), Expect = e-147
 Identities = 262/538 (48%), Positives = 360/538 (66%), Gaps = 11/538 (2%)

Query: 23  LCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARSIPRTVPPDVISLSFVRSGFTEI 82
           L LL+   +    +P K KCP  C+C+KD+ALCE +  +P +  P ++SLS VR+G T++
Sbjct: 8   LLLLAGAGVVVAWRPPKGKCPLRCSCSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQL 67

Query: 83  SEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLI 142
             GSFL  PSL LLLFTSNSF VI DDAF GL HL+YLFIE+N I SIS++  RGL+SL 
Sbjct: 68  KAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLT 127

Query: 143 HLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEG 202
           HLSLANN+L+TLP+ +F+GLD+LT+VDLRGN F CDC++ WL++W+   NA+V    C G
Sbjct: 128 HLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQCDCRVLWLLQWMPTVNASVGTGACAG 187

Query: 203 PPEYKKRKINSLSSKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIF 262
           P      +++ L  K F C   E +  Q +   +LS++ FSY  + ++V+AQPF G+C+ 
Sbjct: 188 PASLSHMQLHHLDPKTFKCRAIELSWFQTVGESALSVEPFSYQGEPHIVLAQPFAGRCLI 247

Query: 263 LEWDHVEKTFRNYDNITGTSTVVCKPIVIETQLYVIVAQLFGGSHIYKRDSFANKFIKIQ 322
           L WD+  + FR  + +   S V CKP+V+   L+V+ A+L+GGS ++ R S   +    Q
Sbjct: 248 LSWDYSLQRFRPEEELPAASVVSCKPLVLGPSLFVLAARLWGGSQLWARPSPGLRLAPTQ 307

Query: 323 DIEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDV 382
            +   ++ +PND E   +E    FVVAD+SKAG TT+   +G GFY HQSLHAW+RDTD 
Sbjct: 308 TLAPRRLLRPNDAELLWLEGQPCFVVADASKAGSTTLLCRDGPGFYPHQSLHAWHRDTDA 367

Query: 383 EYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQLFTNQTDIPNMEDVYAVKHFSVKG 442
           E LE+         PHL+L+S+SQRPV++ W      F  +TDIP  EDVYA +HF   G
Sbjct: 368 EALELD------GRPHLLLASASQRPVLFHWTGGR--FERRTDIPEAEDVYATRHFQAGG 419

Query: 443 DVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVY 502
           DV++CLTR+IGDS VM+W GS F+ +Q++PSRG+ VFQPL I   Q AILGSD++F+QV 
Sbjct: 420 DVFLCLTRYIGDSMVMRWDGSMFRLLQQLPSRGAHVFQPLLIARDQLAILGSDFAFSQVL 479

Query: 503 NWDAEKAKFVKFQELN---VQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA 557
             + +K      QEL    + APR+F H+++  R FLFA+ FKG TQIY+H  +DLSA
Sbjct: 480 RLEPDKGLLEPLQELGPPALVAPRAFAHITMAGRRFLFAACFKGPTQIYQHHEIDLSA 537


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 55/184 (29%), Positives = 89/184 (48%), Gaps = 3/184 (1%)

Query: 40  PKCPAVCTCTKDNALCENA--RSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLL 97
           P+CP  CTC +    C N   R++PR +P DV  L    +  T +          L L+ 
Sbjct: 723 PRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPR-ELSALRHLTLID 781

Query: 98  FTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKD 157
            ++NS  ++++  F  + HL  L +  N ++ I  H F GL+SL  L+L  N++ ++P+ 
Sbjct: 782 LSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEG 841

Query: 158 IFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSK 217
            F  L SL+++ L  N  +CDC L+WL EW+           C  P     R + +  + 
Sbjct: 842 SFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTH 901

Query: 218 DFDC 221
            F C
Sbjct: 902 RFQC 905



 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 26/215 (12%)

Query: 42  CPAVCTCTKDNALC--ENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFT 99
           CP+ CTC+ +   C  +    IP  +P  ++ +   ++    I  G+F     L+ +  +
Sbjct: 280 CPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDIS 339

Query: 100 SNSFDVISDDAFIGLPHLEYLFIENNNIKSISR------------------------HTF 135
            N    I+ DAF GL  L  L +  N I  I++                        +TF
Sbjct: 340 KNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTF 399

Query: 136 RGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATV 195
           + L++L  LSL +N LQT+ K +F  L S+  + L  N F CDC LKWL ++L       
Sbjct: 400 QDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIET 459

Query: 196 EDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQ 230
               C  P     ++I+ + SK F C  +E  +S+
Sbjct: 460 SGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSR 494



 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 62/219 (28%), Positives = 95/219 (43%), Gaps = 27/219 (12%)

Query: 42  CPAVCTCTKDNALCENAR--SIPRTVP-------------------------PDVISLSF 74
           CP  C C      C N +   IP  +P                         P++  ++ 
Sbjct: 505 CPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINL 564

Query: 75  VRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHT 134
             +   E+ EG+F    S+Q L+ T N  + +    F GL  L+ L + +N I  +S  T
Sbjct: 565 SNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDT 624

Query: 135 FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNAT 194
           F GL S+  LSL +N + T+    F  L SL+ ++L  N FNC+C L WL +WL      
Sbjct: 625 FAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIV 684

Query: 195 VEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQDLP 233
             +  C+ P   K+  I  ++ +DF C   E +  Q  P
Sbjct: 685 SGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSP 723



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 64/254 (25%), Positives = 94/254 (37%), Gaps = 55/254 (21%)

Query: 18  RIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENA--RSIPRTVPPDVISLSFV 75
           R+A  L L S L       P    CP  CTC+  +  C     R++PR +P +   L   
Sbjct: 15  RLALALALASVL-----SGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLD 69

Query: 76  RSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGL--------------------- 114
           R+  T I++  F    +L++L    N   VI   AF  L                     
Sbjct: 70  RNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLF 129

Query: 115 ---PHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLR 171
              P L  L +  N I+ I R  FRG+  + +L L NN++  +    F+ L  L  + L 
Sbjct: 130 QSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLN 189

Query: 172 GN--------SFN----------------CDCKLKWLVEWLGHTNATVEDIYCEGPPEYK 207
            N        SFN                CDC L WL +WL       +   C  P   +
Sbjct: 190 NNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLR 249

Query: 208 KRKINSLSSKDFDC 221
              +  +  K++ C
Sbjct: 250 GFNVADVQKKEYVC 263


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 62/212 (29%), Positives = 103/212 (48%), Gaps = 8/212 (3%)

Query: 14  IPLKRIAY--FLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENA--RSIPRTVPPDV 69
           IPL+ +A+  F C        EG    +P+CP  C C      C N   R++P+ +P +V
Sbjct: 707 IPLQDVAFPDFRCEEGQ---EEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNV 763

Query: 70  ISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKS 129
             L    + FT +  G       LQL+  ++N    +S+ +F  +  L  L +  N ++ 
Sbjct: 764 TELYLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQC 822

Query: 130 ISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLG 189
           I    F+GL+SL  LSL  N++ TL + IF  + SL+++ +  N   CDC L+WL  W+ 
Sbjct: 823 IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVK 882

Query: 190 HTNATVEDIYCEGPPEYKKRKINSLSSKDFDC 221
                     C GP + + + + +  +K F+C
Sbjct: 883 TGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 59/210 (28%), Positives = 88/210 (41%), Gaps = 26/210 (12%)

Query: 42  CPAVCTCTKDNALC--ENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFT 99
           CPA+CTC+     C  +   +IP  +P  +  +    +G   I  G+F     L+ +  +
Sbjct: 282 CPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341

Query: 100 SNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGL--------------------- 138
           +N    I+ DAF GL  L  L +  N I  + R  F GL                     
Sbjct: 342 NNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 401

Query: 139 ---KSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATV 195
              ++L  LSL +N +Q+L K  F  L ++  + L  N F CDC LKWL ++L       
Sbjct: 402 QDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIET 461

Query: 196 EDIYCEGPPEYKKRKINSLSSKDFDCIITE 225
               C  P     ++I  + SK F C   E
Sbjct: 462 SGARCASPRRLANKRIGQIKSKKFRCSAKE 491



 Score = 86.3 bits (212), Expect = 7e-17
 Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 27/207 (13%)

Query: 42  CPAVCTCTKDNALCENAR--SIPRTVPPDVISL-------------------------SF 74
           CP  C C  +   C + +   IP  +P     L                         + 
Sbjct: 513 CPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINL 572

Query: 75  VRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHT 134
             +  +EI +G+F    S+  L  T+N  + I    F GL  L  L + NN I  I   +
Sbjct: 573 SNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDS 632

Query: 135 FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNAT 194
           F GL+++  LSL +N + T+    F  L SL+ ++L  N FNC+C+L WL  WL      
Sbjct: 633 FTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIV 692

Query: 195 VEDIYCEGPPEYKKRKINSLSSKDFDC 221
             +  C+ P   ++  +  ++  DF C
Sbjct: 693 TGNPRCQNPDFLRQIPLQDVAFPDFRC 719



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 57/230 (24%), Positives = 82/230 (35%), Gaps = 50/230 (21%)

Query: 42  CPAVCTCTKDNALCENA--RSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLL--- 96
           CPA+CTCT     C     ++IP+ +P +   L    +  T I +  F     L++L   
Sbjct: 34  CPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLM 93

Query: 97  ----------------------------------LF-----------TSNSFDVISDDAF 111
                                             LF           + N+   I   AF
Sbjct: 94  ENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAF 153

Query: 112 IGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLR 171
            G   L+ L ++ N I  I    FR L+ L  L+L NNN+ T+P   F  +  L    L 
Sbjct: 154 RGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLH 213

Query: 172 GNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDC 221
            N   CDC L WL +WL           C GP   +   +  +   +F C
Sbjct: 214 SNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSC 263


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 59/207 (28%), Positives = 90/207 (43%), Gaps = 27/207 (13%)

Query: 42  CPAVCTCTKDNALCENAR--SIPRTVP-------------------------PDVISLSF 74
           CP  C C      C N +   IP  +P                         P +  ++F
Sbjct: 506 CPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINF 565

Query: 75  VRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHT 134
             +  T+I EG+F     +  +L TSN  + +    F GL  L+ L + +N I  +   +
Sbjct: 566 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDS 625

Query: 135 FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNAT 194
           F GL S+  LSL +N + T+    F  L SL+ ++L  N FNC+C L WL EWL      
Sbjct: 626 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIV 685

Query: 195 VEDIYCEGPPEYKKRKINSLSSKDFDC 221
             +  C+ P   K+  I  ++ +DF C
Sbjct: 686 TGNPRCQKPYFLKEIPIQDVAIQDFTC 712



 Score = 93.2 bits (230), Expect = 6e-19
 Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 3/183 (1%)

Query: 41  KCPAVCTCTKDNALCENA--RSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLF 98
           +CP  CTC      C N   + +P+ +P DV  L    + FT + +    +   L L+  
Sbjct: 726 RCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYK-HLTLIDL 784

Query: 99  TSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDI 158
           ++N    +S+ +F  +  L  L +  N ++ I   TF GLKSL  LSL  N++  +P+  
Sbjct: 785 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 844

Query: 159 FKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKD 218
           F  L +L+++ +  N   CDC ++WL +W+           C GP E   + + +  SK 
Sbjct: 845 FNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKK 904

Query: 219 FDC 221
           F C
Sbjct: 905 FTC 907



 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 28/211 (13%)

Query: 42  CPAVCTCTKDNALC--ENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFT 99
           CPA CTC+ +   C  +    IP  +P  +  +   ++    I  G+F     L+ +  +
Sbjct: 273 CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLS 332

Query: 100 SNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSL------------------ 141
           +N    ++ DAF GL  L  L +  N I  + +  F GL SL                  
Sbjct: 333 NNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAF 392

Query: 142 --IH----LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTN-AT 194
             +H    LSL +N LQT+ K  F  L ++  + L  N F CDC LKWL ++L HTN   
Sbjct: 393 QDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYL-HTNPIE 451

Query: 195 VEDIYCEGPPEYKKRKINSLSSKDFDCIITE 225
                C  P     ++I  + SK F C   E
Sbjct: 452 TSGARCTSPRRLANKRIGQIKSKKFRCSAKE 482



 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 63/249 (25%), Positives = 89/249 (35%), Gaps = 50/249 (20%)

Query: 23  LCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENA--RSIPRTVPPDVISLSFVRSGFT 80
           L L   L+L    K A   CPA C+C+     C     RS+PR +P +   L    +  T
Sbjct: 9   LSLSLGLVLAILNKVAPQACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNIT 68

Query: 81  EISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN-------------- 126
            I++  F     L++L    N    I   AF  L  LE L +  N+              
Sbjct: 69  RITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAK 128

Query: 127 ----------IKSISRHTFRG------------------------LKSLIHLSLANNNLQ 152
                     I++I R  FRG                        L+ L  L+L NNN+ 
Sbjct: 129 LYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNIT 188

Query: 153 TLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKIN 212
            L    F  +  L    L  N+  CDC L WL +WL           C GP   +   + 
Sbjct: 189 RLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVA 248

Query: 213 SLSSKDFDC 221
            +  ++F C
Sbjct: 249 EVQKREFVC 257


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 73/230 (31%), Positives = 98/230 (42%), Gaps = 37/230 (16%)

Query: 24  CLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENAR--SIPRTVPPDVISLSFVRSGFTE 81
           C  +  LL     P  P CP+ C C K    C +     IP+ VP     L    +   E
Sbjct: 7   CWTTLFLLAGWCLPGLP-CPSRCLCFKSTVRCMHLMLDHIPQ-VPQQTTVLDLRFNRIRE 64

Query: 82  ISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSL 141
           I   +F    +L  LL  +N    IS +AF GL +L YL++  N I ++ + TF+GL SL
Sbjct: 65  IPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISL 124

Query: 142 IHLS------------------------LANNNLQTLPKDIFKGLDSLTNVDLRGNSFNC 177
            HL                         L NN L  +P   F  LDSL  + L  N+  C
Sbjct: 125 EHLYIHFNQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNALVC 184

Query: 178 DCKLKWLVEWL------GHTNATVEDIYCEGPPEYKKRKINSLSSKDFDC 221
           DC L WL E L      GHT A      CE P     R + S++ ++F+C
Sbjct: 185 DCDLMWLGELLQGFAQHGHTQAAAT---CEYPRRLHGRAVASVTVEEFNC 231


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 68/252 (26%), Positives = 110/252 (43%), Gaps = 43/252 (17%)

Query: 3   SERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENA--RS 60
           ++RS+  G  C+    +A  L      L    +KP    CP+ C C +    C +    +
Sbjct: 2   AKRSRGPGRRCL----LALVLFCAWGTLAVVAQKPGAG-CPSRCLCFRTTVRCMHLLLEA 56

Query: 61  IPRTVPP-DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 119
           +P   P   ++ L F R    EI  G+F    +L  LL  +N    I   AF  L +L+Y
Sbjct: 57  VPAVAPQTSILDLRFNR--IREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKY 114

Query: 120 LFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGL----------------- 162
           L++  N I+SI R  F+GL SL  L L  N ++TL  D F+ L                 
Sbjct: 115 LYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLV 174

Query: 163 -------DSLTNVDLRGNSFNCDCKLKWLVEWL------GHTNATVEDIYCEGPPEYKKR 209
                  +S+  + L  N+ +CDC++ WL + L      G+  A      CE P   + R
Sbjct: 175 PGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAA---ICEYPRRIQGR 231

Query: 210 KINSLSSKDFDC 221
            + +++ ++ +C
Sbjct: 232 SVATITPEELNC 243


>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
          Length = 545

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 2/160 (1%)

Query: 67  PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 126
           P ++ LS   +    ++EG+F    +L+ L+ + N+   +    F  L  L  L++ +NN
Sbjct: 289 PCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNN 348

Query: 127 IKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVE 186
           + ++    F+ L  L  LSL+ N L TLP+ IF    +L N+ L GN + CDC L +L  
Sbjct: 349 LTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYLFN 408

Query: 187 WLGHTNATVEDI--YCEGPPEYKKRKINSLSSKDFDCIIT 224
           WL      + +I  YC GP   K + + +L+ K   C +T
Sbjct: 409 WLQQYTDRLLNIQTYCAGPAYLKGQVVPALNEKQLVCPVT 448



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 51/154 (33%), Positives = 81/154 (52%), Gaps = 6/154 (3%)

Query: 22  FLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALC--ENARSIPRTVPPDVISLSFVRSGF 79
           +L   S LLL    +PA+P CP  C C      C  E   ++P  +PP   ++ FV + F
Sbjct: 6   WLLWTSLLLLA---RPAQP-CPMGCDCFVQEVFCSDEELATVPLDIPPYTKNIIFVETSF 61

Query: 80  TEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLK 139
           T +   +F   P+L  ++F +        DAF GLP LE L +  ++  ++S + F  L 
Sbjct: 62  TTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLT 121

Query: 140 SLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
           SL  L+L  N L+ LP+ +F+ L +L ++ L+GN
Sbjct: 122 SLGKLTLNFNMLEALPEGLFQHLAALESLHLQGN 155



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%)

Query: 71  SLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSI 130
           +L+  ++   ++ E  F    SLQ L  ++N+   +    F  L  L+ LF+++NNI  +
Sbjct: 173 TLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISEL 232

Query: 131 SRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
               F  L  L  L L  N +  LP  IF  L +LT + L+ N
Sbjct: 233 PPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWN 275



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/95 (30%), Positives = 43/95 (45%)

Query: 82  ISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSL 141
           + EG F    +L+ L    N    +    F  L HL+ L +  N +  +    F  L SL
Sbjct: 136 LPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSL 195

Query: 142 IHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 176
             L L+NN L  LP+ +F  L SL  + L  N+ +
Sbjct: 196 QTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNIS 230



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/103 (29%), Positives = 45/103 (43%)

Query: 71  SLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSI 130
           +L    +  + + +G F    SLQ L   SN+   +    F  L  LE L+++ N I  +
Sbjct: 197 TLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHL 256

Query: 131 SRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
               F  L +L  LSL  N L+ LP  +F     L  + L  N
Sbjct: 257 PLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHN 299



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 88  LFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLS 145
           LF P   L+ L    N    + ++ F  L  L+ L + NN +  + +  F  L SL  L 
Sbjct: 164 LFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELF 223

Query: 146 LANNNLQTLPKDIFKGLDSLTNVDLRGNS 174
           L +NN+  LP  +F  L  L  + L+ N+
Sbjct: 224 LDSNNISELPPQVFSQLFCLERLWLQRNA 252



 Score = 32.7 bits (73), Expect = 0.90
 Identities = 21/82 (25%), Positives = 40/82 (48%)

Query: 93  LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 152
           L+ L    N+   +    F  L +L +L ++ N ++ +    F     L+ LSL +N L+
Sbjct: 243 LERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLE 302

Query: 153 TLPKDIFKGLDSLTNVDLRGNS 174
           T+ +  F  L +L ++ L  N+
Sbjct: 303 TVAEGTFAHLSNLRSLMLSYNA 324


>gi|40217825 slit and trk like 6 [Homo sapiens]
          Length = 841

 Score = 86.3 bits (212), Expect = 7e-17
 Identities = 55/162 (33%), Positives = 75/162 (46%), Gaps = 26/162 (16%)

Query: 82  ISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSL 141
           + EGSF+    LQ L    N    +S   F+GL +LEYL++E N IK I   TF  +  L
Sbjct: 402 LEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKL 461

Query: 142 IHLSLANNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNC 177
             L L NN LQ LP  IF G                        LD LT +DL  N ++C
Sbjct: 462 KVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDC 521

Query: 178 DCKLKWLVEWLG--HTNATVEDIYCEGPPEYKKRKINSLSSK 217
            C L  L +W+     N   +DI C  P    K+++ +L+S+
Sbjct: 522 SCDLVGLQQWIQKLSKNTVTDDILCTSPGHLDKKELKALNSE 563



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 57/207 (27%), Positives = 92/207 (44%), Gaps = 29/207 (14%)

Query: 68  DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI 127
           + IS+    +   +I  G+F     L+ L    NS +++ +D F GL +LE+L  +NN I
Sbjct: 89  NAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFI 148

Query: 128 KSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN----------- 176
             I    F  L  L  L L +N +++LP +IF+ +  LT++DLRGN              
Sbjct: 149 TVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFV-PLTHLDLRGNQLQTLPYVGFLEHI 207

Query: 177 --------------CDCKLKWLVEWLGH--TNATVEDIYCEGPPEYKKRKINSLSSKDFD 220
                         C+C L  L  WL +    + + D+ C  PP +K   ++ L  K+  
Sbjct: 208 GRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVVCNSPPFFKGSILSRL-KKESI 266

Query: 221 CIITEFAKSQDLPYQSLSIDTFSYLND 247
           C      +  + P  SL +   S +ND
Sbjct: 267 CPTPPVYEEHEDPSGSLHLAATSSIND 293



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 21/58 (36%), Positives = 30/58 (51%)

Query: 117 LEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNS 174
           LE L + NN I+ +   +F  L  L  L L  N+L  L K +F GL +L  + L  N+
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNA 446



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 120 LFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNS 174
           L + NN +  +  + F GL + I + L  NN+  +    F GL  L  + +  NS
Sbjct: 69  LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNS 123


>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
          Length = 653

 Score = 85.9 bits (211), Expect = 9e-17
 Identities = 54/158 (34%), Positives = 80/158 (50%), Gaps = 7/158 (4%)

Query: 69  VISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 126
           + +L ++  G   I +   L TP   L+ L  + N F  I   +F GL  L+ L++ N+ 
Sbjct: 195 LFNLKYLNLGMCNIKDMPNL-TPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQ 253

Query: 127 IKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVE 186
           +  I R+ F GL SL+ L+LA+NNL +LP D+F  L  L  + L  N +NCDC + WL  
Sbjct: 254 VSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAW 313

Query: 187 WLGH---TNATVEDIYCEGPPEYKKRKINSLSSKDFDC 221
           WL     TN+T     C  P   + R +  +    F C
Sbjct: 314 WLREYIPTNSTCCG-RCHAPMHMRGRYLVEVDQASFQC 350



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 24/153 (15%)

Query: 21  YFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARSIPRTVPPDVISLSFVRSGFT 80
           + LC   A   + G +     CP+VC+C+   +                  +   R G +
Sbjct: 29  WILCAAIAAAASAGPQ----NCPSVCSCSNQFS-----------------KVVCTRRGLS 67

Query: 81  EISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKS 140
           E+ +G    T  L L+    N+  +I  D F  L HLE L +  N+I+ I    F GL S
Sbjct: 68  EVPQGIPSNTRYLNLM---ENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLAS 124

Query: 141 LIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
           L  L L +N L  +P   F+ L  L  + LR N
Sbjct: 125 LNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157


>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
           [Homo sapiens]
          Length = 1093

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 56/170 (32%), Positives = 86/170 (50%), Gaps = 9/170 (5%)

Query: 68  DVISLSFVR---SGFTEISEGSFLFTPSLQLLLFTSNSFDVISDD---AFIGLPHLEYLF 121
           ++ SLS +R   +  + I+EG+F    SL++L    N      +D   AF GL  L  L 
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLT 388

Query: 122 IENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKL 181
           +  N IKS+++  F GL+ L HL+L  N ++++  D F  + +L  + +  +SF CDC+L
Sbjct: 389 LFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQL 448

Query: 182 KWLVEWL-GHTNATVEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQ 230
           KWL  WL G          C  P   K + I S+  + F C   +F K Q
Sbjct: 449 KWLPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPESFVC--DDFLKPQ 496



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 4/154 (2%)

Query: 22  FLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALC--ENARSIPRTVPPDVISLSFVRSGF 79
           +L LL    +T    P  P C A CTC  D+  C      ++P  +P    SL+   +  
Sbjct: 22  WLLLLRLEPVTAAAGPRAP-CAAACTCAGDSLDCGGRGLAALPGDLPSWTRSLNLSYNKL 80

Query: 80  TEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLK 139
           +EI    F   P+LQ +   +N    +         H+  LF+++N I+S+     +   
Sbjct: 81  SEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAAS-SHVVSLFLQHNKIRSVEGSQLKAYL 139

Query: 140 SLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
           SL  L L+ NN+  +    F     +  ++L GN
Sbjct: 140 SLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGN 173



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 29/105 (27%), Positives = 51/105 (48%)

Query: 72  LSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSIS 131
           L   R+  +++++G+F     + +L    NS   ++  +  GL  L  L + NN+I  I 
Sbjct: 240 LKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIH 299

Query: 132 RHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 176
           R  +   + L  L L+ NNL  L ++    L SL+ + L  NS +
Sbjct: 300 RKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSIS 344



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 2/113 (1%)

Query: 62  PRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLF 121
           P   P   ++L+  R G  E+     L + SL  L  + N    +   AF  LP L  L 
Sbjct: 160 PHGPPIKELNLAGNRIGTLELGAFDGL-SRSLLTLRLSKNRITQLPVRAF-KLPRLTQLD 217

Query: 122 IENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNS 174
           +  N I+ I   TF+GL SL  L L  NN+  L    F GL  +  + L  NS
Sbjct: 218 LNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNS 270



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 27/100 (27%), Positives = 46/100 (46%)

Query: 77  SGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFR 136
           +   E++ GS     +L  L  ++NS   I    +     L  L +  NN+  +   +  
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328

Query: 137 GLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 176
            L SL  L L++N++  + +  FKGL SL  +DL  N  +
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEIS 368



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 1/106 (0%)

Query: 69  VISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 128
           +++L   ++  T++   +F   P L  L    N   +I    F GL  LE L ++ NNI 
Sbjct: 190 LLTLRLSKNRITQLPVRAFKL-PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248

Query: 129 SISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNS 174
            ++   F GL  +  L L  N+L  +      GL +L  + L  NS
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNS 294


>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
          Length = 1321

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 46/160 (28%), Positives = 76/160 (47%)

Query: 62  PRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLF 121
           P T+P   ++L    +  +E+  GSF     L+ L   +N    I   AF GL  L+ L 
Sbjct: 76  PDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRLD 135

Query: 122 IENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKL 181
           + NN I  ++   FRGL +L+ L+L+ N   +L +  F  L SL +++ +     CDC +
Sbjct: 136 LTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCNI 195

Query: 182 KWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDC 221
            W+  W+   N TV D  C  P   + + +  +  +   C
Sbjct: 196 LWMHRWVKEKNITVRDTRCVYPKSLQAQPVTGVKQELLTC 235


>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
           [Homo sapiens]
          Length = 1065

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 55/155 (35%), Positives = 80/155 (51%), Gaps = 7/155 (4%)

Query: 80  TEISEGSFLFTPSLQLLLFTSNSFDVISDDA---FIGLPHLEYLFIENNNIKSISRHTFR 136
           T I++G F F  +LQ L   +N      +DA   F GL  L  L ++ N IKSI++  F 
Sbjct: 348 THIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFI 407

Query: 137 GLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVE 196
           GL+SL HL L NN + ++ ++ F     L  + L  +S  CDC LKWL++WL   N    
Sbjct: 408 GLESLEHLDLNNNAIMSIQENAF-SQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHS 466

Query: 197 -DIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQ 230
            ++ C  P     + I ++  KDF C   +F K Q
Sbjct: 467 VNVSCAHPEWLAGQSILNVDLKDFVC--DDFLKPQ 499



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 2/104 (1%)

Query: 72  LSFVRSGFTEISEGSF-LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSI 130
           L+   +  T +  G F   + SL ++    N   +I    F  LPHL++L ++ N IK +
Sbjct: 172 LNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIF-KLPHLQFLELKRNRIKIV 230

Query: 131 SRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNS 174
              TF+GL SL  L +  N +  L    F GL+++  ++L  N+
Sbjct: 231 EGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNN 274



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 31/115 (26%), Positives = 57/115 (49%), Gaps = 6/115 (5%)

Query: 65  VPPDVISLSFV-----RSGFTEISEG-SFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLE 118
           +PP +  L  +     +    +I EG +F    SL+ L    N    + D AF GL ++E
Sbjct: 207 IPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNME 266

Query: 119 YLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
            L +E+NN+  +++    GL+ L  L ++ N ++ +  D ++    L+ +DL  N
Sbjct: 267 ELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYN 321



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 72  LSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSIS 131
           L    +  T +++G       LQ L  + N+ + IS DA+     L  L +  N +  + 
Sbjct: 268 LELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLD 327

Query: 132 RHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVE 186
              F GL  L  L+L +N +  +   +F+ L +L  +DLR N      ++ W +E
Sbjct: 328 ESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNN------EISWAIE 376



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 28/103 (27%), Positives = 50/103 (48%)

Query: 71  SLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSI 130
           SL   R+G +++ +G+F    +++ L    N+   ++     GL  L+ L++  N I+ I
Sbjct: 243 SLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERI 302

Query: 131 SRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
           S   +   + L  L L+ N L  L +  F GL  L  ++L  N
Sbjct: 303 SPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDN 345



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 25/133 (18%)

Query: 68  DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI 127
           ++  LS V +   EI+  +  F P+L+ L  +SN    I   +F  +  L+YL + NN I
Sbjct: 121 NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRM-QLKYLNLSNNRI 179

Query: 128 KSISRHTFRGLKS-LIHLSLANNNLQTLPKDIFK-----------------------GLD 163
            ++    F  L S L+ + L  N +  +P  IFK                       GLD
Sbjct: 180 TTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLD 239

Query: 164 SLTNVDLRGNSFN 176
           SL ++ ++ N  +
Sbjct: 240 SLRSLKMQRNGIS 252


>gi|51317373 netrin-G1 ligand [Homo sapiens]
          Length = 640

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 48/136 (35%), Positives = 70/136 (51%), Gaps = 4/136 (2%)

Query: 90  TPSLQL--LLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
           TP ++L  L  + N    I   +F GL HL+ L++  + I+ I R+ F  L+SL+ ++LA
Sbjct: 216 TPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLA 275

Query: 148 NNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGH--TNATVEDIYCEGPPE 205
           +NNL  LP D+F  L  L  + L  N +NC+C + WL  W+     + T     C  PP 
Sbjct: 276 HNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPN 335

Query: 206 YKKRKINSLSSKDFDC 221
            K R I  L    F C
Sbjct: 336 LKGRYIGELDQNYFTC 351



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 4/150 (2%)

Query: 25  LLSALLLTEGKKPAKPKCPAVCTCTKD--NALC--ENARSIPRTVPPDVISLSFVRSGFT 80
           LL+  LL          CP+VC+C+      +C  +N R +P  +  +   L+   +   
Sbjct: 30  LLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQ 89

Query: 81  EISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKS 140
            I   SF     L++L  + N    I   AF GL +L  L + +N + +I    F  L  
Sbjct: 90  IIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSK 149

Query: 141 LIHLSLANNNLQTLPKDIFKGLDSLTNVDL 170
           L  L L NN ++++P   F  + SL  +DL
Sbjct: 150 LKELWLRNNPIESIPSYAFNRIPSLRRLDL 179



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 71  SLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFI-ENNNIKS 129
           +L    +  T I  G+F++   L+ L   +N  + I   AF  +P L  L + E   +  
Sbjct: 128 TLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSY 187

Query: 130 ISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
           IS   F GL +L +L+LA  NL+ +P      L  L  +DL GN
Sbjct: 188 ISEGAFEGLSNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGN 229


>gi|88702793 slit-like 2 [Homo sapiens]
          Length = 673

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 51/152 (33%), Positives = 72/152 (47%), Gaps = 3/152 (1%)

Query: 25  LLSALLLTEGKKPAKPKCPAVCTCTKDNALCENAR---SIPRTVPPDVISLSFVRSGFTE 81
           LL  LLL     P    CP+ C C++   +   AR   ++PR VPPD + L    +G T 
Sbjct: 7   LLLPLLLLLALGPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITM 66

Query: 82  ISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSL 141
           +  GSF   P LQLL  + N    +    F  L +L  L +  N +  I+  TFRGL+ L
Sbjct: 67  LDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRL 126

Query: 142 IHLSLANNNLQTLPKDIFKGLDSLTNVDLRGN 173
             L L  N ++ +    F  LD L  + L+ N
Sbjct: 127 ERLYLGKNRIRHIQPGAFDTLDRLLELKLQDN 158



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 45/161 (27%), Positives = 68/161 (42%), Gaps = 5/161 (3%)

Query: 68  DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN- 126
           +V +L     G  ++ EG F    +L  L  + N  + +      GL  L  L +  N  
Sbjct: 193 NVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGNTR 251

Query: 127 IKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVE 186
           I  +      GL +L  L ++N +LQ LP D+      L  +    N FNC C L W   
Sbjct: 252 IAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGP 311

Query: 187 WLGHTNATV---EDIYCEGPPEYKKRKINSLSSKDFDCIIT 224
           W+  ++ T+   E+  C  PP+   R +  L   DF C  T
Sbjct: 312 WVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPAT 352


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 4/114 (3%)

Query: 112 IGLP--HLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVD 169
           + LP  +L  L++++N+I  +  + F  L+ L  L ++NNNL  LP+ IF  LD++T + 
Sbjct: 242 VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301

Query: 170 LRGNSFNCDCKLKWLVEWLGH--TNATVEDIYCEGPPEYKKRKINSLSSKDFDC 221
           LR N + C CK+KW+ +WL        V  + C+ P + +   I  L+++ FDC
Sbjct: 302 LRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAELFDC 355



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 26/156 (16%)

Query: 42  CPAVCTCTKDNALCENA--RSIPRTVPPDVISLSFVRSGFTEIS-----------EGSFL 88
           CP+VC C      C +    SIP  +P D  +L    +                 E  +L
Sbjct: 31  CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYL 90

Query: 89  FTPSL-----------QLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSIS--RHTF 135
           +  SL           + L    N+   I+ D+   +P+LE L +++N++ ++S     F
Sbjct: 91  YHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAF 150

Query: 136 RGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLR 171
           R    L  L L+ N+L T+P  + + ++ L   D R
Sbjct: 151 RDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNR 186


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 4/114 (3%)

Query: 112 IGLP--HLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVD 169
           + LP  +L  L++++N+I  +  + F  L+ L  L ++NNNL  LP+ IF  LD++T + 
Sbjct: 242 VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLI 301

Query: 170 LRGNSFNCDCKLKWLVEWLGH--TNATVEDIYCEGPPEYKKRKINSLSSKDFDC 221
           LR N + C CK+KW+ +WL        V  + C+ P + +   I  L+++ FDC
Sbjct: 302 LRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAELFDC 355



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 26/156 (16%)

Query: 42  CPAVCTCTKDNALCENA--RSIPRTVPPDVISLSFVRSGFTEIS-----------EGSFL 88
           CP+VC C      C +    SIP  +P D  +L    +                 E  +L
Sbjct: 31  CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYL 90

Query: 89  FTPSL-----------QLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSIS--RHTF 135
           +  SL           + L    N+   I+ D+   +P+LE L +++N++ ++S     F
Sbjct: 91  YHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAF 150

Query: 136 RGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLR 171
           R    L  L L+ N+L T+P  + + ++ L   D R
Sbjct: 151 RDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNR 186


>gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 60/257 (23%)

Query: 21  YFLCLLSA--LLLTEGKKPAKPKCPAVCTCT-KDNAL---CENA--RSIPRTVPP----- 67
           +FL +L+   +L TE +K AK  C   C C  K+N L   CEN    ++    PP     
Sbjct: 6   WFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIY 65

Query: 68  ---------------------DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI 106
                                + ++L    +G  EI  G+F    +L+ L   +N  +++
Sbjct: 66  QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125

Query: 107 SDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLT 166
            +D F+GL  LEYL  + N I +I    F  L  L  L L +N L +LP ++F+ +  LT
Sbjct: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLT 184

Query: 167 NVDLRG-------------------------NSFNCDCKLKWLVEWLGHTNATVEDIYCE 201
           ++DLRG                         N +NC C L  L  WL      V +I CE
Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244

Query: 202 GPPEYKKRKINSLSSKD 218
            P     + +  L+ +D
Sbjct: 245 TPFRLHGKDVTQLTRQD 261



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 77/311 (24%), Positives = 121/311 (38%), Gaps = 69/311 (22%)

Query: 2   ESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTK---DNALCENA 58
           ++ R  +M N   P   ++        +++ + K P    CP+ C CT    DN L  N 
Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359

Query: 59  RSI---------PRTVPPDVI-------------------SLSFVRSGFTEIS---EGSF 87
           +           P+   P  +                   SL  +  G   I+   EG+F
Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAF 419

Query: 88  LFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLA 147
               SL+ L    N  +V+    F GL  L+YL++E N IK I   TF  L +L  L L 
Sbjct: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479

Query: 148 NNNLQTLPKDIFKG------------------------LDSLTNVDLRGNSFNCDCKLKW 183
           NN L++LP +IF G                        L +   +DL+ N ++C C +  
Sbjct: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539

Query: 184 LVEWLGHTNATV--EDIYCEGPPEYKKRKINSLSSKDF--------DCIITEFAKSQDLP 233
           L +W  H N+ V   ++ CE P ++    +  L  +          D  +     + D P
Sbjct: 540 LKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTP 599

Query: 234 YQSLSIDTFSY 244
            +SLS+   SY
Sbjct: 600 -RSLSVSPSSY 609


>gi|194272183 G protein-coupled receptor 124 [Homo sapiens]
          Length = 1338

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 1/161 (0%)

Query: 62  PRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLF 121
           P  +P   ++L    +  T +  GSFL    L+ L   +N    +   AF+GL  L+ L 
Sbjct: 79  PGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLD 138

Query: 122 IENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKL 181
           + NN I  ++  TF+GL  L+ L+++ N   +L   +F  L +L  VDL      CDC L
Sbjct: 139 LSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHL 198

Query: 182 KWLVEWLGHTNATV-EDIYCEGPPEYKKRKINSLSSKDFDC 221
           +WL+ W  + +  + E   C  P     + + SL      C
Sbjct: 199 RWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 239


>gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]
          Length = 420

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 46/163 (28%), Positives = 77/163 (47%), Gaps = 3/163 (1%)

Query: 60  SIPRTVPPDVISLSFV---RSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPH 116
           S+P  +   ++SL ++    +    + +  F    +L  L    N   ++++  F GL  
Sbjct: 145 SLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGS 204

Query: 117 LEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 176
           L+ L +  N ++ + R  FRGL  L  L L NN+L +LP +    L SL  + L  N + 
Sbjct: 205 LDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPWA 264

Query: 177 CDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDF 219
           CDC+ + L  W      +  D+ C  PPE + R + +L   DF
Sbjct: 265 CDCRARPLWAWFQRARVSSSDVTCATPPERQGRDLRALREADF 307



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 51/156 (32%), Positives = 74/156 (47%), Gaps = 10/156 (6%)

Query: 24  CLLSALLLTEGKKPAKPKCPAVCTCTKD----NALCENARSIPRTVPPDVISLSFVRSGF 79
           CLL  LL       A P CP +CTC       +    N  S+P ++PP    L    +  
Sbjct: 16  CLLLMLLALP---LAAPSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLI 72

Query: 80  TEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFI-ENNNIKSISRHTFRGL 138
             +  G+  F  +L  L   SN+   I    F  L  LE L + +N +++S+   TF+GL
Sbjct: 73  RTLRPGT--FGSNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGL 130

Query: 139 KSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNS 174
           + L  L L    L +LP +IF+GL SL  + L+ NS
Sbjct: 131 ERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENS 166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,427,155
Number of Sequences: 37866
Number of extensions: 880816
Number of successful extensions: 3143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 1773
Number of HSP's gapped (non-prelim): 831
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.