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Search of human proteins with 13375926
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13375926 vacuolar protein sorting 37B [Homo sapiens]
(285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13375926 vacuolar protein sorting 37B [Homo sapiens] 568 e-162
gi|57863314 vacuolar protein sorting 37C [Homo sapiens] 166 3e-41
gi|117938318 vacuolar protein sorting 37D [Homo sapiens] 127 1e-29
gi|223555921 hepatocellular carcinoma related protein 1 isoform ... 88 1e-17
gi|223555919 hepatocellular carcinoma related protein 1 isoform ... 88 1e-17
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 66 4e-11
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 66 4e-11
gi|153792074 proline rich 12 [Homo sapiens] 63 3e-10
gi|160707881 formin 2 [Homo sapiens] 62 4e-10
gi|33356148 formin-like 1 [Homo sapiens] 59 4e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens] 58 8e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 56 4e-08
gi|157168329 formin 1 [Homo sapiens] 55 7e-08
gi|56549694 enabled homolog isoform a [Homo sapiens] 55 7e-08
gi|39930375 enabled homolog isoform b [Homo sapiens] 55 7e-08
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 55 7e-08
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 55 7e-08
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 55 7e-08
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 55 9e-08
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 55 9e-08
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 55 9e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 55 9e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 54 1e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 54 2e-07
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 54 2e-07
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 54 2e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 2e-07
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 54 2e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 3e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 53 3e-07
>gi|13375926 vacuolar protein sorting 37B [Homo sapiens]
Length = 285
Score = 568 bits (1465), Expect = e-162
Identities = 285/285 (100%), Positives = 285/285 (100%)
Query: 1 MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNL 60
MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNL
Sbjct: 1 MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNL 60
Query: 61 LYQPQLDTLKARLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEED 120
LYQPQLDTLKARLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEED
Sbjct: 61 LYQPQLDTLKARLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEED 120
Query: 121 TENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRL 180
TENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRL
Sbjct: 121 TENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRL 180
Query: 181 PELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQC 240
PELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQC
Sbjct: 181 PELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQC 240
Query: 241 PPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFILQ 285
PPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFILQ
Sbjct: 241 PPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFILQ 285
>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
Length = 355
Score = 166 bits (419), Expect = 3e-41
Identities = 122/332 (36%), Positives = 171/332 (51%), Gaps = 66/332 (19%)
Query: 14 SLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKARL 73
+L +L EL D + ++ + E Q++QL +EM LA+NRSLAE NL +Q L+ ++ L
Sbjct: 8 TLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNL 67
Query: 74 TQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGEL 133
+ +YQEL+ L E Q +K KL++ SS+ TLL LLQ EG KIEE++E MAEKFL+GE+
Sbjct: 68 SDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEV 127
Query: 134 PLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQ------------RLPQALAPLP---P 178
PL++F++ + S R L+H+RRV++EKLQE+V K + R P + P+P P
Sbjct: 128 PLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVPQGTP 187
Query: 179 RLPELAPTAPL---PYPAPEASGPP----AVAPRRIPPPPPPVP------AGRLATPFTA 225
+ E P PL PYP P + P A +PP P PV +G L + A
Sbjct: 188 PVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPA 247
Query: 226 AM-----------SSGQAVP----YPGLQC----PPLPPRVGLPTQQGFSSQFVSPYP-- 264
A S +++P YPG P P R G G+ Q SPYP
Sbjct: 248 AQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQ--SPYPAT 305
Query: 265 ---PPLPQRPP------------PRLPPHQPG 281
PP P +P P PP+ PG
Sbjct: 306 GGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPG 337
Score = 29.6 bits (65), Expect = 3.2
Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 8/47 (17%)
Query: 175 PLPPRLPELA----PTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAG 217
P+ P+LP P+ PL P P PP PPPP P G
Sbjct: 312 PIQPQLPSFPGQPQPSVPLQPPYPPGPAPPY----GFPPPPGPAWPG 354
>gi|117938318 vacuolar protein sorting 37D [Homo sapiens]
Length = 251
Score = 127 bits (319), Expect = 1e-29
Identities = 84/214 (39%), Positives = 119/214 (55%), Gaps = 6/214 (2%)
Query: 5 GSEARFAGLSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQP 64
GS RF LS QL +LL+DE +L +V+ + Q +QL +E LASN +LA+ NL +P
Sbjct: 14 GSPGRFGILSTGQLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRP 73
Query: 65 QLDTLKARLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENM 124
+L+ +A L KYQEL+ + E K +L+ S L LQAE + E++ E
Sbjct: 74 RLEMGRAALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQ 133
Query: 125 AEKFLDGELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELA 184
E+ L GE L++F+ +Q R LAH+RR + EKLQE++ + +R Q AP P +
Sbjct: 134 MEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQP-APTSAADPPKS 192
Query: 185 PTAPLPYPAPEASGPPAVAPRRIPP----PPPPV 214
A P A GPPAV PR +PP P PP+
Sbjct: 193 FPAAAVLPTGAARGPPAV-PRSLPPLDSRPVPPL 225
>gi|223555921 hepatocellular carcinoma related protein 1 isoform 2
[Homo sapiens]
Length = 372
Score = 87.8 bits (216), Expect = 1e-17
Identities = 47/151 (31%), Positives = 81/151 (53%)
Query: 13 LSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKAR 72
LS+ QL ++ E E L E + + + + +K+ + S LA NLL +P L+ +
Sbjct: 212 LSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQT 271
Query: 73 LTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGE 132
+ KY+ L + ++ K + S S S L A L+ + EE+++N+AE FL+G+
Sbjct: 272 VLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGK 331
Query: 133 LPLDSFIDVYQSKRKLAHMRRVKIEKLQEMV 163
+ +D F+ + KR + H RR K EKLQ+ +
Sbjct: 332 MEIDDFLSSFMEKRTICHCRRAKEEKLQQAI 362
>gi|223555919 hepatocellular carcinoma related protein 1 isoform 1
[Homo sapiens]
Length = 397
Score = 87.8 bits (216), Expect = 1e-17
Identities = 47/151 (31%), Positives = 81/151 (53%)
Query: 13 LSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKAR 72
LS+ QL ++ E E L E + + + + +K+ + S LA NLL +P L+ +
Sbjct: 237 LSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQT 296
Query: 73 LTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGE 132
+ KY+ L + ++ K + S S S L A L+ + EE+++N+AE FL+G+
Sbjct: 297 VLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGK 356
Query: 133 LPLDSFIDVYQSKRKLAHMRRVKIEKLQEMV 163
+ +D F+ + KR + H RR K EKLQ+ +
Sbjct: 357 MEIDDFLSSFMEKRTICHCRRAKEEKLQQAI 387
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 65.9 bits (159), Expect = 4e-11
Identities = 71/276 (25%), Positives = 114/276 (41%), Gaps = 54/276 (19%)
Query: 22 LEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKARLTQKYQELQ 81
+E EG + +M+ K + ++ E+ + L + L Q ++ +++ QK Q+LQ
Sbjct: 450 IEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHEL-QVEMKKMESDFEQKLQDLQ 508
Query: 82 VLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGELPLDSFIDV 141
+A +K ++ + LE ++ L E AK+ ++ E+
Sbjct: 509 GEKDALHSEKQQIATEKQD--LEAEVSQLTGEVAKLTKELED------------------ 548
Query: 142 YQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPR--LPELAPTAPLPYPAPEASGP 199
+K+++A + I + + AP+PP LP + T P PAP S
Sbjct: 549 --AKKEMASLSAAAITVPPSVPSR--------APVPPAPPLPGDSGTIIPPPPAPGDSTT 598
Query: 200 PAVAPRRIPPP-----------PPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVG 248
P P PPP PP +P G +P +S +P P PPLP VG
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP-PPPLSGDATIPPP----PPLPEGVG 653
Query: 249 LPTQQGFSSQFVSPYPPPLP---QRPPPRLPPHQPG 281
+P+ P PPPLP + PPP PP PG
Sbjct: 654 IPSPSSLPGGTAIPPPPPLPGSARIPPP--PPPLPG 687
Score = 57.4 bits (137), Expect = 1e-08
Identities = 41/109 (37%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 172 ALAPLPPRLPE-LAPTAPLPYPAPEASGPPAVAP--RRIPPPPPPVPAGRLATPFTAAMS 228
A P PP LPE + +P P A PP P RIPPPPPP+P P +
Sbjct: 640 ATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLP 699
Query: 229 SGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
+P P PPLP G+P F P PPP PPP PP
Sbjct: 700 GEAGMPPPP---PPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPP--PP 743
Score = 56.6 bits (135), Expect = 2e-08
Identities = 40/118 (33%), Positives = 48/118 (40%), Gaps = 21/118 (17%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIP-----PPPPPVPAGRLATPF 223
LP A PP P L+ A +P P P G +P +P PPPPP+P P
Sbjct: 624 LPGGTAISPP--PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 681
Query: 224 TAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPG 281
+ +P P PPLP G+P P PPPLP P PP PG
Sbjct: 682 PPPLPGSAGIPPPP---PPLPGEAGMP-----------PPPPPLPGGPGIPPPPPFPG 725
Score = 44.7 bits (104), Expect = 9e-05
Identities = 35/101 (34%), Positives = 41/101 (40%), Gaps = 28/101 (27%)
Query: 173 LAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIP-----PPPPPVPAGRLATPFTAAM 227
+ P PP LP A P P P P +G P P +P PPPPP P G
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP-LPGGPGIPPPPPFPGG---------- 726
Query: 228 SSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLP 268
PG+ PP PP +G+P F F P P LP
Sbjct: 727 --------PGI--PPPPPGMGMPPPPPFG--FGVPAAPVLP 755
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 65.9 bits (159), Expect = 4e-11
Identities = 71/276 (25%), Positives = 114/276 (41%), Gaps = 54/276 (19%)
Query: 22 LEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKARLTQKYQELQ 81
+E EG + +M+ K + ++ E+ + L + L Q ++ +++ QK Q+LQ
Sbjct: 459 IEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHEL-QVEMKKMESDFEQKLQDLQ 517
Query: 82 VLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGELPLDSFIDV 141
+A +K ++ + LE ++ L E AK+ ++ E+
Sbjct: 518 GEKDALHSEKQQIATEKQD--LEAEVSQLTGEVAKLTKELED------------------ 557
Query: 142 YQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPR--LPELAPTAPLPYPAPEASGP 199
+K+++A + I + + AP+PP LP + T P PAP S
Sbjct: 558 --AKKEMASLSAAAITVPPSVPSR--------APVPPAPPLPGDSGTIIPPPPAPGDSTT 607
Query: 200 PAVAPRRIPPP-----------PPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVG 248
P P PPP PP +P G +P +S +P P PPLP VG
Sbjct: 608 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP-PPPLSGDATIPPP----PPLPEGVG 662
Query: 249 LPTQQGFSSQFVSPYPPPLP---QRPPPRLPPHQPG 281
+P+ P PPPLP + PPP PP PG
Sbjct: 663 IPSPSSLPGGTAIPPPPPLPGSARIPPP--PPPLPG 696
Score = 57.4 bits (137), Expect = 1e-08
Identities = 41/109 (37%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 172 ALAPLPPRLPE-LAPTAPLPYPAPEASGPPAVAP--RRIPPPPPPVPAGRLATPFTAAMS 228
A P PP LPE + +P P A PP P RIPPPPPP+P P +
Sbjct: 649 ATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLP 708
Query: 229 SGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
+P P PPLP G+P F P PPP PPP PP
Sbjct: 709 GEAGMPPPP---PPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPP--PP 752
Score = 56.6 bits (135), Expect = 2e-08
Identities = 40/118 (33%), Positives = 48/118 (40%), Gaps = 21/118 (17%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIP-----PPPPPVPAGRLATPF 223
LP A PP P L+ A +P P P G +P +P PPPPP+P P
Sbjct: 633 LPGGTAISPP--PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690
Query: 224 TAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPG 281
+ +P P PPLP G+P P PPPLP P PP PG
Sbjct: 691 PPPLPGSAGIPPPP---PPLPGEAGMP-----------PPPPPLPGGPGIPPPPPFPG 734
Score = 44.7 bits (104), Expect = 9e-05
Identities = 35/101 (34%), Positives = 41/101 (40%), Gaps = 28/101 (27%)
Query: 173 LAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIP-----PPPPPVPAGRLATPFTAAM 227
+ P PP LP A P P P P +G P P +P PPPPP P G
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP-LPGGPGIPPPPPFPGG---------- 735
Query: 228 SSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLP 268
PG+ PP PP +G+P F F P P LP
Sbjct: 736 --------PGI--PPPPPGMGMPPPPPFG--FGVPAAPVLP 764
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 62.8 bits (151), Expect = 3e-10
Identities = 42/118 (35%), Positives = 49/118 (41%), Gaps = 20/118 (16%)
Query: 170 PQALAPLPPRLPEL-------APTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATP 222
P A P PP LP L P PL P + PPA P+ PPPPPP P L +P
Sbjct: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
Query: 223 FTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+ + P P L P PP +P SP PPP P P PP +P
Sbjct: 1486 PPLVAPTPSSPPPPPL---PPPPPPAMP----------SPPPPPPPAAAPLAAPPEEP 1530
Score = 44.7 bits (104), Expect = 9e-05
Identities = 36/118 (30%), Positives = 39/118 (33%), Gaps = 25/118 (21%)
Query: 181 PELAPTAPLPYP----------APEASGPPAVAPRRIPPPPPPVPAGRLATPF------- 223
P APT P P GP P R PP PP P L T F
Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252
Query: 224 ----TAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
A SS Q + G P PP LP Q + Y P +PPP PP
Sbjct: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQ----DTVIKHYQRPASAQPPPPPPP 306
Score = 43.1 bits (100), Expect = 3e-04
Identities = 36/110 (32%), Positives = 39/110 (35%), Gaps = 27/110 (24%)
Query: 175 PLPPRLPELAPTAPLPYPAPEA---SGPPAVAPR-RIPPPPPPVPAGRLATPFTAAMSSG 230
P PP P P P P P P+ S PP VAP PPPPP P
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP------------PPP 1506
Query: 231 QAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
A+P P PP PP P P P P P LP +P
Sbjct: 1507 PAMPSP----PPPPPPAAAPLA-------APPEEPAAPSPEDPELPDTRP 1545
Score = 42.4 bits (98), Expect = 5e-04
Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS 229
PQ P PP L P++P P P P P +P PPPPPP A A P A S
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP---PPPPPPAAAPLAAPPEEPAAPS 1534
Query: 230 GQAVPYP 236
+ P
Sbjct: 1535 PEDPELP 1541
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/121 (29%), Positives = 51/121 (42%), Gaps = 22/121 (18%)
Query: 160 QEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRL 219
++ V K + L ++++ L + P P+ GPP +AP P PPP+P
Sbjct: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPD--GPP-LAPAAAVPGPPPLPG--- 1438
Query: 220 ATPFTAAMSSGQAVPYPGL---QCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLP 276
+A S+G P P L + PP PP P Q P PPP P +P P
Sbjct: 1439 ---LPSANSNG--TPEPPLLEEKPPPTPPPAPTPQPQ--------PPPPPPPPQPALPSP 1485
Query: 277 P 277
P
Sbjct: 1486 P 1486
Score = 38.5 bits (88), Expect = 0.007
Identities = 32/113 (28%), Positives = 41/113 (36%), Gaps = 13/113 (11%)
Query: 177 PPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPP---PVPAGRLATPFTAAMSSG--- 230
PP P T P P+ +G P + P +PPPPP P +P +A G
Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDL-PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 231 ------QAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
P P PP PP + L + S + P P RP L P
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP 876
Score = 37.7 bits (86), Expect = 0.012
Identities = 29/92 (31%), Positives = 33/92 (35%), Gaps = 9/92 (9%)
Query: 194 PEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGL-----QCPPLPPRVG 248
PE G P P PP P G P+ +SG PGL + P LP V
Sbjct: 968 PEDEGDPKAGAGPPPGPPAYDPYG----PYCPGRASGAGPETPGLGLDPNKPPELPSTVN 1023
Query: 249 LPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
S PPP P PPP P +P
Sbjct: 1024 AEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 37.4 bits (85), Expect = 0.015
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 21/90 (23%)
Query: 205 RRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGF--------- 255
++ PPPPPP TP + +G P L PP PP++ LP+
Sbjct: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGG--PDLPLVLPPPPPQL-LPSVLSHAPSPSPSAS 817
Query: 256 ---------SSQFVSPYPPPLPQRPPPRLP 276
+++ +P PPP P PPP +P
Sbjct: 818 KVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847
Score = 33.5 bits (75), Expect = 0.22
Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 31/142 (21%)
Query: 166 GQRLPQALAPLPPRL-PELAPTAPLPYPAPEA-----------SGPPAVAPRRIPPPPP- 212
G LP L P PP+L P + AP P P+ G P P PPPPP
Sbjct: 787 GPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM 846
Query: 213 --PVPAGRLATPFTAAMSSGQAVPYPGLQCP-----------PLPPR-----VGLPTQQG 254
+ A + A S + P L P PLPP VG P +G
Sbjct: 847 PLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEG 906
Query: 255 FSSQFVSPYPPPLPQRPPPRLP 276
P P + P +P
Sbjct: 907 KDPAGAYRSPSPQGTKAPRFVP 928
Score = 31.6 bits (70), Expect = 0.83
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 1/99 (1%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS 229
P+A A PP P P P +GP P PP +P+ A P S
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033
Query: 230 GQAVPYPGLQCPPLPPRVGLPTQQGFSSQ-FVSPYPPPL 267
P PP PP + G +S F S P L
Sbjct: 1034 PHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKL 1072
Score = 29.6 bits (65), Expect = 3.2
Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 13/89 (14%)
Query: 178 PRLPELAPTAPLPYPAPEASGPPAVA-------PRRIPPPPPPVPAGRLATPFTAAMSSG 230
P+L + AP P P PE + P P PPPPP PA L + S
Sbjct: 263 PQLYNFSGAAPGP-PPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYP 321
Query: 231 QAVPYPGLQCPPL-----PPRVGLPTQQG 254
L C PL P G P++ G
Sbjct: 322 SMGHRANLACSPLGGGEPSPGAGEPSKAG 350
Score = 29.6 bits (65), Expect = 3.2
Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 6/68 (8%)
Query: 179 RLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYP-- 236
R P L P +P S PP+V R + P PP PA P + A G A+
Sbjct: 1294 RHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP-SGAFGLGGALEAAES 1352
Query: 237 ---GLQCP 241
GL CP
Sbjct: 1353 EGLGLGCP 1360
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 62.4 bits (150), Expect = 4e-10
Identities = 43/113 (38%), Positives = 46/113 (40%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A PLPP LP P P P PP + IPPPPP AG P
Sbjct: 959 LPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018
Query: 229 SGQAVPYPGLQCPPLP--PRVGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP P P G+P + P PPPLP PPP LP
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1070
Score = 61.2 bits (147), Expect = 1e-09
Identities = 43/113 (38%), Positives = 46/113 (40%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P
Sbjct: 1025 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 229 SGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP VG+P + P PPPLP PPP LP
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1136
Score = 61.2 bits (147), Expect = 1e-09
Identities = 42/113 (37%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P +
Sbjct: 1047 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1106
Query: 229 SGQAVPYPGLQCPPLP--PRVGLPTQQGFSSQFVSPYPPPLPQ---RPPPRLP 276
P PG PP P P G+P + P PPPLP+ PPP LP
Sbjct: 1107 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPRVGIPPPPPLP 1158
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P
Sbjct: 948 LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007
Query: 229 SGQAVPYPGLQCPPLP--PRVGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP P P G+P + P PPPLP PPP LP
Sbjct: 1008 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1059
Score = 60.8 bits (146), Expect = 1e-09
Identities = 44/125 (35%), Positives = 50/125 (40%), Gaps = 8/125 (6%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P +
Sbjct: 1124 LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1183
Query: 229 SGQAVPYPGLQCPPLP--PRVGLPTQQGFSSQFVSPYP-PPLPQ-----RPPPRLPPHQP 280
P PG+ PP P P G+P + P P PPLP PPP LP P
Sbjct: 1184 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGP 1243
Query: 281 GFILQ 285
+ Q
Sbjct: 1244 PLLPQ 1248
Score = 60.5 bits (145), Expect = 2e-09
Identities = 43/113 (38%), Positives = 46/113 (40%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP A P P P PP + IPPPPP AG P
Sbjct: 937 LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996
Query: 229 SGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1048
Score = 60.1 bits (144), Expect = 2e-09
Identities = 42/113 (37%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP + P P P PP + IPPPPP AG P +
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150
Query: 229 SGQAVPYPGLQCPPLP--PRVGLPTQQGFSSQFVSPYPPPLPQ---RPPPRLP 276
P PG PP P P G+P + P PPPLP PPP LP
Sbjct: 1151 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP-PPPLPGVGIPPPPPLP 1202
Score = 59.7 bits (143), Expect = 3e-09
Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P
Sbjct: 970 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1029
Query: 229 SGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 1030 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1081
Score = 59.7 bits (143), Expect = 3e-09
Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P
Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
Query: 229 SGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1092
Score = 59.7 bits (143), Expect = 3e-09
Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P
Sbjct: 992 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
Query: 229 SGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1103
Score = 59.3 bits (142), Expect = 4e-09
Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P
Sbjct: 1003 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1062
Query: 229 SGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQ---RPPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 1063 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGVGIPPPPPLP 1114
Score = 59.3 bits (142), Expect = 4e-09
Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
LP A P PP LP P P P PP + IPPPPP AG P
Sbjct: 1014 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1073
Query: 229 SGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 1074 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP-PPPLPGAGIPPPPPLP 1125
Score = 56.6 bits (135), Expect = 2e-08
Identities = 45/114 (39%), Positives = 49/114 (42%), Gaps = 19/114 (16%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEAS-GPPAVAPRRIPPPPPPVPAGRLATPFTAAM 227
LP A P PP LP A PLP P P A PP P PPPPP+P + P
Sbjct: 915 LPGAGIPPPPPLPG-AGILPLP-PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP----- 967
Query: 228 SSGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 968 -----PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1015
Score = 55.8 bits (133), Expect = 4e-08
Identities = 42/118 (35%), Positives = 48/118 (40%), Gaps = 12/118 (10%)
Query: 164 LKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPF 223
L G +P + P+ P L T LP P PP + IPPPPP AG L P
Sbjct: 883 LPGMTVPTLPSTAIPQPPPLQGTEMLPPP------PPPLPGAGIPPPPPLPGAGILPLPP 936
Query: 224 TAAMSSGQAVPYPGLQCPPLPPR--VGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
P PG PP PP G+P + P PPPLP PPP LP
Sbjct: 937 LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP-PPPLPGAGIPPPPPLP 993
Score = 55.1 bits (131), Expect = 7e-08
Identities = 39/113 (34%), Positives = 47/113 (41%), Gaps = 24/113 (21%)
Query: 175 PLPPRLPELA----PTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSG 230
P PP LP + P+ +P P PP +PPPPPP+P + P
Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQP------PPLQGTEMLPPPPPPLPGAGIPPP-------- 923
Query: 231 QAVPYPGLQCPPLP--PRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPG 281
P PG PLP P G+P + P PPPLP P LPP PG
Sbjct: 924 --PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP-PPPLPGAGIP-LPPPLPG 972
Score = 45.8 bits (107), Expect = 4e-05
Identities = 40/110 (36%), Positives = 46/110 (41%), Gaps = 26/110 (23%)
Query: 187 APLPYPAPEASGP-PAVAPRRIPPPPPPVPAGRLAT-PFTA----------AMSSGQAVP 234
+P P P E+S P + +PPPPPP+P + T P TA M P
Sbjct: 857 SPPPLPCTESSSSMPGLG--MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914
Query: 235 YPGLQCPPLPPRVG-----LPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
PG PP PP G LP G P PPPLP PPP LP
Sbjct: 915 LPGAGIPPPPPLPGAGILPLPPLPGAG----IPPPPPLPGAAIPPPPPLP 960
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/119 (33%), Positives = 45/119 (37%), Gaps = 37/119 (31%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPP--------------PV 214
LP A P PP LP + P P P PP + IPPPPP P
Sbjct: 1168 LPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
Query: 215 PAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVG---LPTQQ--GFSSQFVSPYPPPLP 268
P + P P + PPL P+VG LPT Q GF PPPLP
Sbjct: 1228 PGTGIPPP-----------PLLPVSGPPLLPQVGSSTLPTPQVCGF-------LPPPLP 1268
Score = 36.2 bits (82), Expect = 0.034
Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 28/84 (33%)
Query: 209 PPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGL-------------PTQQGF 255
P PPP+P S ++P G+ PP PP G+ P QG
Sbjct: 856 PSPPPLPC----------TESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQG- 904
Query: 256 SSQFVSPYPPPLPQR---PPPRLP 276
++ + P PPPLP PPP LP
Sbjct: 905 -TEMLPPPPPPLPGAGIPPPPPLP 927
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 59.3 bits (142), Expect = 4e-09
Identities = 74/277 (26%), Positives = 109/277 (39%), Gaps = 52/277 (18%)
Query: 14 SLVQLNELLEDEGQLTEMVQKMEETQN--VQLNKEMTLASNRSLAEGNLLYQPQLDTLKA 71
++ + LLED +++ MEE Q L + + A N S+A+ + L+
Sbjct: 380 NIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAK--------IAELEK 431
Query: 72 RLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDG 131
+L+Q +EL+ L E + + T + E + +E E + EK L
Sbjct: 432 QLSQARKELETLRERFS-ESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGL-- 488
Query: 132 ELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPY 191
++I + + + LP A+A P P P
Sbjct: 489 ----------------------IRILRGPGDAVSIEILPVAVAT-PSGGDAPTPGVPTGS 525
Query: 192 PAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS-GQAVPYPGL-QCPPLPPRVG- 248
P+P+ + AP PPPPPP+P L +P A S+ QA P PG + PP PP G
Sbjct: 526 PSPDLAPAAEPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGD 583
Query: 249 LPTQQGFSSQFVSPYPPPL----PQRPPPRLPPHQPG 281
LP P PPP P PPP PP PG
Sbjct: 584 LPPPP-------PPPPPPPGTDGPVPPPPPPPPPPPG 613
Score = 28.9 bits (63), Expect = 5.4
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 12/54 (22%)
Query: 193 APEASGPPAVAPRRIPPPPPPVP-AGRLATPFTAAMSSGQAVPYPGLQCPPLPP 245
A + +GP A P++ PP P+P AG L F A L C LPP
Sbjct: 8 AEQPAGPAAPPPKQPAPPKQPMPAAGELEERFNRA-----------LNCMNLPP 50
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 58.2 bits (139), Expect = 8e-09
Identities = 44/125 (35%), Positives = 54/125 (43%), Gaps = 16/125 (12%)
Query: 164 LKGQRLPQALAPL--PPRLPELAPTAPLPYPAPEASGPPAVAPR-RIPPPPPPVPAGRLA 220
L G + ++P PP P +P P P AP + PP P IPPPPPPV G
Sbjct: 286 LAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPG 345
Query: 221 TPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQ----RPPPRLP 276
TP S P+P PP PP ++ + + PPPL Q PPP P
Sbjct: 346 TP--PPPSPPSFPPHPDFAAPPPPPPPP-------AADYPTLPPPPLSQPTGGAPPPPPP 396
Query: 277 PHQPG 281
P PG
Sbjct: 397 PPPPG 401
Score = 40.0 bits (92), Expect = 0.002
Identities = 37/104 (35%), Positives = 43/104 (41%), Gaps = 25/104 (24%)
Query: 175 PLPPRLPELAP----TAPLPYPAPEASGPPAVAPRRI-------PPPPPP-VPAGRLATP 222
P PP P P AP P P P A+ P + P + PPPPPP P G P
Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406
Query: 223 FTAAMSSGQ-AVPYPGLQCPPL----PPRVGLPTQQGFSSQFVS 261
FT A GQ A+P PPL P+ LP S +S
Sbjct: 407 FTGA--DGQPAIP------PPLSDTTKPKSSLPAVSDARSDLLS 442
Score = 35.8 bits (81), Expect = 0.044
Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 8/100 (8%)
Query: 184 APTAPLPYPAPEASGP-PAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPP 242
A + P P + AS P P+ + +PPPP + P SG A P P
Sbjct: 243 ASSYPPPPQSDSASSPSPSFSEDNLPPPP-----AEFSYPVDNQRGSGLAGPKRSSVVSP 297
Query: 243 L--PPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
PP L + G F P PP P P +PP P
Sbjct: 298 SHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP 337
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 55.8 bits (133), Expect = 4e-08
Identities = 45/141 (31%), Positives = 57/141 (40%), Gaps = 28/141 (19%)
Query: 154 VKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPL---PYPAPEASGPPAVAPRRIPPP 210
+KI ++Q + P P+P LP AP PL P P + P V P P
Sbjct: 747 LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806
Query: 211 PPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLP-PRVGLPTQQGFSSQFVSPYPPPLP- 268
PPVP + F A+ +P P PP+P P LP QQ F ++ PPP P
Sbjct: 807 TPPVPPAKKQPAFPASY-----IP-PSPPTPPVPVPPPTLPKQQSFCAK-----PPPSPL 855
Query: 269 ------------QRPPPRLPP 277
Q PPP PP
Sbjct: 856 SPVPSVVKQIASQFPPPPTPP 876
Score = 52.4 bits (124), Expect = 5e-07
Identities = 41/120 (34%), Positives = 52/120 (43%), Gaps = 21/120 (17%)
Query: 169 LPQALAPLPP-------RLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLAT 221
LPQ AP PP + ++AP P P P A PP P+ + P P +A
Sbjct: 737 LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796
Query: 222 PFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYP--PPLPQRPPPRLPPHQ 279
T A A P P PP+PP Q F + ++ P P PP+P PPP LP Q
Sbjct: 797 VVTQA-----APPTP---TPPVPPA---KKQPAFPASYIPPSPPTPPVPV-PPPTLPKQQ 844
Score = 48.5 bits (114), Expect = 7e-06
Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 27/146 (18%)
Query: 149 AHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIP 208
A R ++E+ + ++ P + +PP P+ P PY A + S P P P
Sbjct: 580 AWKRGTQLEESSKARMESMNRPYT-SLVPPLSPQ--PKIVTPYTASQPSPPLPPPPPPPP 636
Query: 209 PPPPPVPAGRLATPFTAAMSSGQAVPY-----------------PGLQCPPLPPRVGLPT 251
PPPPP P P +A S+G A P L PP PP +
Sbjct: 637 PPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPP---VMQ 693
Query: 252 QQGFSSQFVSP----YPPPLPQRPPP 273
Q Q + P PPP P PPP
Sbjct: 694 SQSVKPQILVPPNGVVPPPPPPPPPP 719
Score = 45.1 bits (105), Expect = 7e-05
Identities = 34/101 (33%), Positives = 39/101 (38%), Gaps = 9/101 (8%)
Query: 181 PELAPTAPLPYPAPEASGPP-AVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQ 239
P P P+ PP V P PPPPPP P +A A A P
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPC----APSLPQFS 741
Query: 240 CPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
PP P ++ Q +Q P PPP P P P LPP P
Sbjct: 742 APPPPLKI---HQVQHITQVAPPTPPPPPPIPAP-LPPQAP 778
Score = 44.3 bits (103), Expect = 1e-04
Identities = 37/111 (33%), Positives = 42/111 (37%), Gaps = 16/111 (14%)
Query: 177 PPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYP 236
PP LP+ P P+P + P V PPPP P AM S P P
Sbjct: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP---------PAMESQPLKPVP 887
Query: 237 GLQCPPLPPRV-GLPTQQGFSSQFVSP-YPPPLPQR-----PPPRLPPHQP 280
P PP V P Q S SP +PPP P+ PPP P P
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/110 (30%), Positives = 42/110 (38%), Gaps = 20/110 (18%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEA--SGPPAVAPRRIPPPPPPVPAGRLATPFTAAM 227
P L+P+P + ++A P P P P A S P P + P PP +
Sbjct: 852 PSPLSPVPSVVKQIASQFP-PPPTPPAMESQPLKPVPANVAPQSPPAVKAK-------PK 903
Query: 228 SSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
++P P PP PP S V P PPP P PP PP
Sbjct: 904 WQPSSIPVPSPDFPPPPP----------ESSLVFPPPPPSPVPAPPPPPP 943
Score = 39.3 bits (90), Expect = 0.004
Identities = 33/109 (30%), Positives = 44/109 (40%), Gaps = 21/109 (19%)
Query: 171 QALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPP------PPVPAGRLATPFT 224
Q L P+P + +P A P + S P +P PPPP PP P + P
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP-- 938
Query: 225 AAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSP---YPPPLPQR 270
P P P P + G P ++ +S+ SP PPP PQR
Sbjct: 939 --------PPPPPPTASPTPDKSGSPGKK--TSKTSSPGGKKPPPTPQR 977
Score = 38.1 bits (87), Expect = 0.009
Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 26/70 (37%)
Query: 211 PPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQR 270
PP P ++ TP+TA+ S PPLPP P PPP P
Sbjct: 607 PPLSPQPKIVTPYTASQPS-----------PPLPP---------------PPPPPPPPPP 640
Query: 271 PPPRLPPHQP 280
PPP PP P
Sbjct: 641 PPPPPPPPLP 650
Score = 35.8 bits (81), Expect = 0.044
Identities = 34/125 (27%), Positives = 46/125 (36%), Gaps = 17/125 (13%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
+P PP PE + P P P+P + PP P P P G+ T T++
Sbjct: 909 IPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK-KTSKTSSPG 967
Query: 229 SGQAVPYPGLQCP---------PLPPRVGLPTQQGFSSQFVSPYPPPLPQR---PPPRLP 276
+ P P P P R P+ S+F P P + PPP P
Sbjct: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKR---PSVDSLVSKFTPPAESGSPSKETLPPPAAP 1024
Query: 277 PHQPG 281
P +PG
Sbjct: 1025 P-KPG 1028
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 55.1 bits (131), Expect = 7e-08
Identities = 41/110 (37%), Positives = 47/110 (42%), Gaps = 25/110 (22%)
Query: 170 PQALAPLPPRLPE----LAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTA 225
P A P PP LP L+P P+P P ++GPP P PPPPPP+P A P
Sbjct: 648 PPASIPPPPPLPSGLGSLSPAPPMP---PVSAGPPLPPP---PPPPPPLPPPSSAGP--- 698
Query: 226 AMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRL 275
P P L P PP G P +P PP L PPP L
Sbjct: 699 ----PPPPPPPPLPNSPAPPNPGGPPP--------APPPPGLAPPPPPGL 736
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/124 (34%), Positives = 47/124 (37%), Gaps = 20/124 (16%)
Query: 159 LQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGR 218
LQ M +AL P P +P P PLP S P + P PP PP P
Sbjct: 631 LQPMEGMASNQQKALPPPPASIP---PPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP- 686
Query: 219 LATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRL-PP 277
P S+G P P PPLP P G PPP P PPP L PP
Sbjct: 687 -PPPLPPPSSAGPPPPPPP---PPLPNSPAPPNPGG---------PPPAP--PPPGLAPP 731
Query: 278 HQPG 281
PG
Sbjct: 732 PPPG 735
Score = 38.9 bits (89), Expect = 0.005
Identities = 29/81 (35%), Positives = 32/81 (39%), Gaps = 9/81 (11%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVA-PRRIPPPP---PPVPAGRLATPFTA 225
P PLPP P P P P P + PP P PPPP PP P G F
Sbjct: 684 PPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLF---FGL 740
Query: 226 AMSSGQAVPYPGLQ--CPPLP 244
SS Q P ++ CP P
Sbjct: 741 GSSSSQCPRKPAIEPSCPMKP 761
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 55.1 bits (131), Expect = 7e-08
Identities = 65/263 (24%), Positives = 105/263 (39%), Gaps = 41/263 (15%)
Query: 37 ETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKARLTQKYQELQVLFEAYQIKKTKLDR 96
+ QN +E+ + R L E Q Q + + RL ++ E + L E ++++ +L+R
Sbjct: 130 QVQNGPSQEELEI-QRRQLQE----QQRQKELERERLERERMERERL-ERERLERERLER 183
Query: 97 QSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKI 156
+ + ++E ++ L+ + LD Q + +L + R +
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQ 243
Query: 157 EKLQEMVLKGQ--------RLPQALAPLPPRLP--ELAPTAPLPYPAPEASGPPAVAPRR 206
E+ ++ L+ + R+ A AP P + + P +A+ PA P +
Sbjct: 244 ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQ 303
Query: 207 --------IPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQ 258
PPPPPP+P G A +S P PG PP P G P
Sbjct: 304 QGIVLGPLAPPPPPPLPPG-------PAQASVALPPPPGPPPPPPLPSTGPPP------- 349
Query: 259 FVSPYPPPLP-QRPPPRLPPHQP 280
P PPPLP Q PPP PP P
Sbjct: 350 --PPPPPPLPNQVPPPPPPPPAP 370
Score = 49.3 bits (116), Expect = 4e-06
Identities = 63/252 (25%), Positives = 97/252 (38%), Gaps = 30/252 (11%)
Query: 16 VQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKA-RLT 74
+Q +L E + Q E+ ++ E + ++ + R E L Q QL+ + R
Sbjct: 142 IQRRQLQEQQRQ-KELERERLERERMERERLERERLERERLERERLEQEQLERERQERER 200
Query: 75 QKYQELQVLFEAYQI--KKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKF---- 128
Q+ E Q E + ++ +LDR+ L L+ E + E + E+
Sbjct: 201 QERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWER 260
Query: 129 ----------LDGELPLDSFI-DVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLP 177
E PL+S + D S+ L + Q+ ++ G P PLP
Sbjct: 261 ERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLP 320
Query: 178 PRLPELA----------PTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRL-ATPFTAA 226
P + + P PLP P PP P ++PPPPPP PA L A+ F A
Sbjct: 321 PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLA 380
Query: 227 MSSGQAVPYPGL 238
S P GL
Sbjct: 381 SMSEDNRPLTGL 392
Score = 45.4 bits (106), Expect = 6e-05
Identities = 37/105 (35%), Positives = 41/105 (39%), Gaps = 33/105 (31%)
Query: 180 LPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQ 239
L LAP P P P A A+ P PPPPPP+P S+G P P
Sbjct: 308 LGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLP------------STGPPPPPPP-- 353
Query: 240 CPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFIL 284
PPLP +V P PPP PPP P GF L
Sbjct: 354 -PPLPNQV--------------PPPPP----PPPAPPLPASGFFL 379
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 55.1 bits (131), Expect = 7e-08
Identities = 65/263 (24%), Positives = 105/263 (39%), Gaps = 41/263 (15%)
Query: 37 ETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKARLTQKYQELQVLFEAYQIKKTKLDR 96
+ QN +E+ + R L E Q Q + + RL ++ E + L E ++++ +L+R
Sbjct: 130 QVQNGPSQEELEI-QRRQLQE----QQRQKELERERLERERMERERL-ERERLERERLER 183
Query: 97 QSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKI 156
+ + ++E ++ L+ + LD Q + +L + R +
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQ 243
Query: 157 EKLQEMVLKGQ--------RLPQALAPLPPRLP--ELAPTAPLPYPAPEASGPPAVAPRR 206
E+ ++ L+ + R+ A AP P + + P +A+ PA P +
Sbjct: 244 ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQ 303
Query: 207 --------IPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQ 258
PPPPPP+P G A +S P PG PP P G P
Sbjct: 304 QGIVLGPLAPPPPPPLPPG-------PAQASVALPPPPGPPPPPPLPSTGPPP------- 349
Query: 259 FVSPYPPPLP-QRPPPRLPPHQP 280
P PPPLP Q PPP PP P
Sbjct: 350 --PPPPPPLPNQVPPPPPPPPAP 370
Score = 49.3 bits (116), Expect = 4e-06
Identities = 63/252 (25%), Positives = 97/252 (38%), Gaps = 30/252 (11%)
Query: 16 VQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKA-RLT 74
+Q +L E + Q E+ ++ E + ++ + R E L Q QL+ + R
Sbjct: 142 IQRRQLQEQQRQ-KELERERLERERMERERLERERLERERLERERLEQEQLERERQERER 200
Query: 75 QKYQELQVLFEAYQI--KKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKF---- 128
Q+ E Q E + ++ +LDR+ L L+ E + E + E+
Sbjct: 201 QERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWER 260
Query: 129 ----------LDGELPLDSFI-DVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLP 177
E PL+S + D S+ L + Q+ ++ G P PLP
Sbjct: 261 ERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLP 320
Query: 178 PRLPELA----------PTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRL-ATPFTAA 226
P + + P PLP P PP P ++PPPPPP PA L A+ F A
Sbjct: 321 PGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLA 380
Query: 227 MSSGQAVPYPGL 238
S P GL
Sbjct: 381 SMSEDNRPLTGL 392
Score = 45.4 bits (106), Expect = 6e-05
Identities = 37/105 (35%), Positives = 41/105 (39%), Gaps = 33/105 (31%)
Query: 180 LPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQ 239
L LAP P P P A A+ P PPPPPP+P S+G P P
Sbjct: 308 LGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLP------------STGPPPPPPP-- 353
Query: 240 CPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFIL 284
PPLP +V P PPP PPP P GF L
Sbjct: 354 -PPLPNQV--------------PPPPP----PPPAPPLPASGFFL 379
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 55.1 bits (131), Expect = 7e-08
Identities = 41/116 (35%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 171 QALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSG 230
+ ++P+P LP P P+P PAP PP V P + P PPV FT +
Sbjct: 653 EPVSPIPKPLP--VPVPPIPVPAPITVPPPQVPPHQ---PGPPVVGALQPPAFTPPLGIP 707
Query: 231 QAVPYPGLQCPPLPPRVGLPTQQGFSSQ-----FVSPYPPPLPQRPPPRL-PPHQP 280
PG+ PP PP P GF+ F+ P PPP P PP + PPH P
Sbjct: 708 PPGFGPGVPPPPPPPPFLRP---GFNPMHLPPGFLPPGPPP-PITPPVSIPPPHTP 759
Score = 48.5 bits (114), Expect = 7e-06
Identities = 37/106 (34%), Positives = 45/106 (42%), Gaps = 10/106 (9%)
Query: 184 APTAPLPYPAPEASGPPAVAPRRIPPPPPPVP-----AGRLATPFTAAMSSGQAVP-YPG 237
AP A +P PAP A+ P A AP PPPP P G +T + Q P G
Sbjct: 289 APAAAVP-PAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347
Query: 238 LQCPPLPPRVGLP---TQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+Q P+ +V LP GF P+PP PP P QP
Sbjct: 348 IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 29/138 (21%)
Query: 175 PLPPRLPELAPTA-PLPYPA---PEASGPPAVAPRRIPPP-PPPVPAGRLATPFTAAMSS 229
P PP P L P P+ P P PP P IPPP PP+ L + S
Sbjct: 717 PPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAES 776
Query: 230 GQAVPYPGLQCPPLPPRVGLPTQ----------------------QGFSSQFVSPYPPPL 267
G +V G PP P LPT Q S+ + P +
Sbjct: 777 GDSVKMYGSAVPPAAP-TNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLI 835
Query: 268 P-QRPPPRLPPHQPGFIL 284
P QRPP PPH F L
Sbjct: 836 PLQRPPGMPPPHLQRFPL 853
Score = 37.4 bits (85), Expect = 0.015
Identities = 29/88 (32%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 197 SGPPAVAPRRIPPPPPPVPAGRLATPFTA--------AMSSGQAVPYPGLQCPPLPPRVG 248
S P AP +P PP P L T A A S+G PGL PP +
Sbjct: 785 SAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP 844
Query: 249 LPTQQGFSSQFVSPYPPPLPQRPPPRLP 276
P Q F P PP + R PP P
Sbjct: 845 PPHLQRFPLMPPRPMPPHMMHRGPPPGP 872
Score = 35.8 bits (81), Expect = 0.044
Identities = 32/107 (29%), Positives = 36/107 (33%), Gaps = 2/107 (1%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAA 226
QR P L P P P + P P P A PP PP P V G +
Sbjct: 849 QRFP--LMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG 906
Query: 227 MSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPP 273
G G Q PP P+ Q Q PP Q+PPP
Sbjct: 907 PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 953
Score = 33.1 bits (74), Expect = 0.29
Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 260 VSPYPPPLPQR-PPPRLPPHQPG 281
V P P P P PPP++PPHQPG
Sbjct: 666 VPPIPVPAPITVPPPQVPPHQPG 688
Score = 29.6 bits (65), Expect = 3.2
Identities = 37/114 (32%), Positives = 41/114 (35%), Gaps = 14/114 (12%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAA 226
QR P P R P L P P+P P GPP P PPP G PF
Sbjct: 838 QRPPGMPPPHLQRFP-LMPPRPMP-PHMMHRGPPP-GPGGFAMPPPHGMKG----PFPPH 890
Query: 227 MSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+ PGL P P G P + Q PP PQ+ P P QP
Sbjct: 891 GPFVRPGGMPGLGGP--GPGPGGPEDRDGRQQ-----PPQQPQQQPQPQAPQQP 937
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 55.1 bits (131), Expect = 7e-08
Identities = 41/116 (35%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 171 QALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSG 230
+ ++P+P LP P P+P PAP PP V P + P PPV FT +
Sbjct: 638 EPVSPIPKPLP--VPVPPIPVPAPITVPPPQVPPHQ---PGPPVVGALQPPAFTPPLGIP 692
Query: 231 QAVPYPGLQCPPLPPRVGLPTQQGFSSQ-----FVSPYPPPLPQRPPPRL-PPHQP 280
PG+ PP PP P GF+ F+ P PPP P PP + PPH P
Sbjct: 693 PPGFGPGVPPPPPPPPFLRP---GFNPMHLPPGFLPPGPPP-PITPPVSIPPPHTP 744
Score = 48.5 bits (114), Expect = 7e-06
Identities = 37/106 (34%), Positives = 45/106 (42%), Gaps = 10/106 (9%)
Query: 184 APTAPLPYPAPEASGPPAVAPRRIPPPPPPVP-----AGRLATPFTAAMSSGQAVP-YPG 237
AP A +P PAP A+ P A AP PPPP P G +T + Q P G
Sbjct: 274 APAAAVP-PAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 332
Query: 238 LQCPPLPPRVGLP---TQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+Q P+ +V LP GF P+PP PP P QP
Sbjct: 333 IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 378
Score = 37.4 bits (85), Expect = 0.015
Identities = 29/88 (32%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 197 SGPPAVAPRRIPPPPPPVPAGRLATPFTA--------AMSSGQAVPYPGLQCPPLPPRVG 248
S P AP +P PP P L T A A S+G PGL PP +
Sbjct: 792 SAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP 851
Query: 249 LPTQQGFSSQFVSPYPPPLPQRPPPRLP 276
P Q F P PP + R PP P
Sbjct: 852 PPHLQRFPLMPPRPMPPHMMHRGPPPGP 879
Score = 35.8 bits (81), Expect = 0.044
Identities = 32/107 (29%), Positives = 36/107 (33%), Gaps = 2/107 (1%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAA 226
QR P L P P P + P P P A PP PP P V G +
Sbjct: 856 QRFP--LMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG 913
Query: 227 MSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPP 273
G G Q PP P+ Q Q PP Q+PPP
Sbjct: 914 PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 960
Score = 33.1 bits (74), Expect = 0.29
Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 260 VSPYPPPLPQR-PPPRLPPHQPG 281
V P P P P PPP++PPHQPG
Sbjct: 651 VPPIPVPAPITVPPPQVPPHQPG 673
Score = 30.8 bits (68), Expect = 1.4
Identities = 44/160 (27%), Positives = 52/160 (32%), Gaps = 51/160 (31%)
Query: 175 PLPPRLPELAPTA-PLPYPA---PEASGPPAVAPRRIPPPPPP---VPAGRLA------- 220
P PP P L P P+ P P PP P IPPP P +P +A
Sbjct: 702 PPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTT 761
Query: 221 ------TPFTAAMS-------SGQAVPYPGLQCPPLPPRVGLPTQ--------------- 252
P +S SG +V G PP P LPT
Sbjct: 762 KDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAP-TNLPTPPVTQPVSLLGTQGVA 820
Query: 253 -------QGFSSQFVSPYPPPLP-QRPPPRLPPHQPGFIL 284
Q S+ + P +P QRPP PPH F L
Sbjct: 821 PGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPL 860
Score = 29.6 bits (65), Expect = 3.2
Identities = 37/114 (32%), Positives = 41/114 (35%), Gaps = 14/114 (12%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAA 226
QR P P R P L P P+P P GPP P PPP G PF
Sbjct: 845 QRPPGMPPPHLQRFP-LMPPRPMP-PHMMHRGPPP-GPGGFAMPPPHGMKG----PFPPH 897
Query: 227 MSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+ PGL P P G P + Q PP PQ+ P P QP
Sbjct: 898 GPFVRPGGMPGLGGP--GPGPGGPEDRDGRQQ-----PPQQPQQQPQPQAPQQP 944
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 55.1 bits (131), Expect = 7e-08
Identities = 41/116 (35%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 171 QALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSG 230
+ ++P+P LP P P+P PAP PP V P + P PPV FT +
Sbjct: 653 EPVSPIPKPLP--VPVPPIPVPAPITVPPPQVPPHQ---PGPPVVGALQPPAFTPPLGIP 707
Query: 231 QAVPYPGLQCPPLPPRVGLPTQQGFSSQ-----FVSPYPPPLPQRPPPRL-PPHQP 280
PG+ PP PP P GF+ F+ P PPP P PP + PPH P
Sbjct: 708 PPGFGPGVPPPPPPPPFLRP---GFNPMHLPPGFLPPGPPP-PITPPVSIPPPHTP 759
Score = 48.5 bits (114), Expect = 7e-06
Identities = 37/106 (34%), Positives = 45/106 (42%), Gaps = 10/106 (9%)
Query: 184 APTAPLPYPAPEASGPPAVAPRRIPPPPPPVP-----AGRLATPFTAAMSSGQAVP-YPG 237
AP A +P PAP A+ P A AP PPPP P G +T + Q P G
Sbjct: 289 APAAAVP-PAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347
Query: 238 LQCPPLPPRVGLP---TQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+Q P+ +V LP GF P+PP PP P QP
Sbjct: 348 IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393
Score = 37.4 bits (85), Expect = 0.015
Identities = 29/88 (32%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 197 SGPPAVAPRRIPPPPPPVPAGRLATPFTA--------AMSSGQAVPYPGLQCPPLPPRVG 248
S P AP +P PP P L T A A S+G PGL PP +
Sbjct: 807 SAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP 866
Query: 249 LPTQQGFSSQFVSPYPPPLPQRPPPRLP 276
P Q F P PP + R PP P
Sbjct: 867 PPHLQRFPLMPPRPMPPHMMHRGPPPGP 894
Score = 35.8 bits (81), Expect = 0.044
Identities = 32/107 (29%), Positives = 36/107 (33%), Gaps = 2/107 (1%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAA 226
QR P L P P P + P P P A PP PP P V G +
Sbjct: 871 QRFP--LMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG 928
Query: 227 MSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPP 273
G G Q PP P+ Q Q PP Q+PPP
Sbjct: 929 PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 975
Score = 33.1 bits (74), Expect = 0.29
Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 260 VSPYPPPLPQR-PPPRLPPHQPG 281
V P P P P PPP++PPHQPG
Sbjct: 666 VPPIPVPAPITVPPPQVPPHQPG 688
Score = 30.8 bits (68), Expect = 1.4
Identities = 44/160 (27%), Positives = 52/160 (32%), Gaps = 51/160 (31%)
Query: 175 PLPPRLPELAPTA-PLPYPA---PEASGPPAVAPRRIPPPPPP---VPAGRLA------- 220
P PP P L P P+ P P PP P IPPP P +P +A
Sbjct: 717 PPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTT 776
Query: 221 ------TPFTAAMS-------SGQAVPYPGLQCPPLPPRVGLPTQ--------------- 252
P +S SG +V G PP P LPT
Sbjct: 777 KDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAP-TNLPTPPVTQPVSLLGTQGVA 835
Query: 253 -------QGFSSQFVSPYPPPLP-QRPPPRLPPHQPGFIL 284
Q S+ + P +P QRPP PPH F L
Sbjct: 836 PGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPL 875
Score = 29.6 bits (65), Expect = 3.2
Identities = 37/114 (32%), Positives = 41/114 (35%), Gaps = 14/114 (12%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAA 226
QR P P R P L P P+P P GPP P PPP G PF
Sbjct: 860 QRPPGMPPPHLQRFP-LMPPRPMP-PHMMHRGPPP-GPGGFAMPPPHGMKG----PFPPH 912
Query: 227 MSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+ PGL P P G P + Q PP PQ+ P P QP
Sbjct: 913 GPFVRPGGMPGLGGP--GPGPGGPEDRDGRQQ-----PPQQPQQQPQPQAPQQP 959
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 54.7 bits (130), Expect = 9e-08
Identities = 44/114 (38%), Positives = 45/114 (39%), Gaps = 9/114 (7%)
Query: 177 PPRLPELAPTAPLPYPAPEASGPPAVAPR-RIPPPPPPVPAGRLATPFTAAMSSGQAV-- 233
PP P P P P P SGPP R R PPPPP A A P AV
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
Query: 234 PYPGLQCPPLPPRVGLPTQQG-----FSSQFVSPY-PPPLPQRPPPRLPPHQPG 281
P P PP PP + G S V P PPP P PPP PP PG
Sbjct: 337 PPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPG 390
Score = 49.7 bits (117), Expect = 3e-06
Identities = 39/114 (34%), Positives = 43/114 (37%), Gaps = 14/114 (12%)
Query: 182 ELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVP-----YP 236
EL AP P P PP P PPPP GR A P + + A P P
Sbjct: 271 ELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330
Query: 237 GLQCPPLPP-RVGLPTQQGFSSQFVSPYPPPLPQ--------RPPPRLPPHQPG 281
+ PP PP R+ P S S PPP P PPP PP PG
Sbjct: 331 SVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPG 384
Score = 42.7 bits (99), Expect = 4e-04
Identities = 21/39 (53%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 175 PLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPP 213
P PP LP AP+ P P P P G VAP PPPPPP
Sbjct: 345 PPPPALPSSAPSGPPP-PPPSVLGVGPVAPPPPPPPPPP 382
Score = 38.5 bits (88), Expect = 0.007
Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 9/86 (10%)
Query: 170 PQALAPL--PPRLPELAPTAPLPYPAPEAS--GPPAVAPRRIPPPPPPVPAGRLATPFTA 225
P + AP PP P P+ +P P P PP P P PPP P L A
Sbjct: 313 PPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVA 372
Query: 226 AMSSGQAVPYPGLQCPPLPPRVGLPT 251
P PG PP PP GLP+
Sbjct: 373 PPPPPPPPPPPG---PPPPP--GLPS 393
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 54.7 bits (130), Expect = 9e-08
Identities = 41/108 (37%), Positives = 47/108 (43%), Gaps = 12/108 (11%)
Query: 177 PPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYP 236
P L + A T P P P P G A PPPPP P + A ++ P P
Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSA------EPPPPPPPPPLPSVGAKALPTAPPPPPLP 464
Query: 237 GL--QCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRP-PPRLPPHQPG 281
GL PP PP LP S +F+ P PPPLP PP PP PG
Sbjct: 465 GLGAMAPPAPP---LPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPG 509
Score = 28.5 bits (62), Expect = 7.0
Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 1/59 (1%)
Query: 173 LAPLPPRLPELA-PTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSG 230
L P PP LP L P P P GPP P +P P AG + A + G
Sbjct: 487 LPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHG 545
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 54.7 bits (130), Expect = 9e-08
Identities = 41/108 (37%), Positives = 47/108 (43%), Gaps = 12/108 (11%)
Query: 177 PPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYP 236
P L + A T P P P P G A PPPPP P + A ++ P P
Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSA------EPPPPPPPPPLPSVGAKALPTAPPPPPLP 464
Query: 237 GL--QCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRP-PPRLPPHQPG 281
GL PP PP LP S +F+ P PPPLP PP PP PG
Sbjct: 465 GLGAMAPPAPP---LPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPG 509
Score = 28.5 bits (62), Expect = 7.0
Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 1/59 (1%)
Query: 173 LAPLPPRLPELA-PTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSG 230
L P PP LP L P P P GPP P +P P AG + A + G
Sbjct: 487 LPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHG 545
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 54.7 bits (130), Expect = 9e-08
Identities = 43/125 (34%), Positives = 46/125 (36%), Gaps = 24/125 (19%)
Query: 172 ALAPLPPRLPELAPTA-----------PLPYPAPEASGPPAVAPRRI------PPPPPPV 214
A P PPR P AP A P P PAP A+ PA APR PP P P
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
Query: 215 PAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPR 274
G A + A P PP PR P V+ PPLP P P
Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPA-------VAAREPPLPPPPQPP 218
Query: 275 LPPHQ 279
PP Q
Sbjct: 219 APPQQ 223
Score = 48.1 bits (113), Expect = 9e-06
Identities = 43/120 (35%), Positives = 46/120 (38%), Gaps = 29/120 (24%)
Query: 170 PQALAPLPPRLP-------------ELAPTAPLPYPAPEASGPPA--VAPRRIPPPPPPV 214
P AP PP P A TAP P P P GP A AP PPP P
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAP-PSPGPAQPGPRAQRAAPLAAPPPAPAA 186
Query: 215 PAGRLATPFTAAMSSGQAVPYPGLQC--PPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPP 272
P P A + + P P + PPLPP P Q Q P PPP PQ PP
Sbjct: 187 P------PAVAPPAGPRRAPPPAVAAREPPLPP----PPQPPAPPQQQQP-PPPQPQPPP 235
Score = 47.4 bits (111), Expect = 1e-05
Identities = 44/136 (32%), Positives = 53/136 (38%), Gaps = 17/136 (12%)
Query: 153 RVKIEKL--QEMVL----KGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRR 206
R ++EKL Q VL KG + A + P P T P P AP + A A
Sbjct: 70 RAELEKLIQQRAVLRVSYKGSISYRNAARVQP--PRRGATPPAPPRAPRGAPAAAAAAAP 127
Query: 207 IPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPY--P 264
P P PP P P A ++ P PP G P Q G +Q +P P
Sbjct: 128 PPTPAPPPP------PAPVAAAAPARAPRAAAAAATAPPSPG-PAQPGPRAQRAAPLAAP 180
Query: 265 PPLPQRPPPRLPPHQP 280
PP P PP PP P
Sbjct: 181 PPAPAAPPAVAPPAGP 196
Score = 42.0 bits (97), Expect = 6e-04
Identities = 32/86 (37%), Positives = 35/86 (40%), Gaps = 21/86 (24%)
Query: 171 QALAPL--PPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
Q APL PP P AP A P P + PPAVA R P PPPP P
Sbjct: 172 QRAAPLAAPPPAPA-APPAVAPPAGPRRAPPPAVAAREPPLPPPPQP------------- 217
Query: 229 SGQAVPYPGLQCPPLPPRVGLPTQQG 254
P P Q P PP+ P + G
Sbjct: 218 -----PAPPQQQQPPPPQPQPPPEGG 238
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 54.3 bits (129), Expect = 1e-07
Identities = 51/196 (26%), Positives = 77/196 (39%), Gaps = 23/196 (11%)
Query: 85 EAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGELPLDSFIDVYQS 144
E Y + R+ + ++ + + +G E + D E DS ++
Sbjct: 668 ERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSE---DSETEMAPK 724
Query: 145 KRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAP 204
+K H R E+ + Q++ QA AP+P + P P P P P P+ P
Sbjct: 725 SKKKGHPGR---EQKKHHHHHHQQMQQAPAPVPQQPPP-PPQQPPPPPPPQQQQQP---- 776
Query: 205 RRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYP 264
PPPPPP + A P AM S P+ Q P L P++ G + +
Sbjct: 777 ---PPPPPPPSMPQQAAP---AMKSSPP-PFIATQVPVLEPQL-----PGSVFDPIGHFT 824
Query: 265 PPLPQRPPPRLPPHQP 280
P+ P P LPPH P
Sbjct: 825 QPILHLPQPELPPHLP 840
Score = 45.4 bits (106), Expect = 6e-05
Identities = 40/120 (33%), Positives = 48/120 (40%), Gaps = 18/120 (15%)
Query: 161 EMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLA 220
+M L Q+L Q + P P LP + + P P P P + PPPPP P
Sbjct: 927 QMQLYLQQL-QKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP----- 980
Query: 221 TPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
Q P P Q P P V L Q FS+ P PPP Q+PP P QP
Sbjct: 981 ----------QPQPPPQQQHQPPPRPVHLQPMQ-FSTHIQQP-PPPQGQQPPHPPPGQQP 1028
Score = 40.4 bits (93), Expect = 0.002
Identities = 47/148 (31%), Positives = 54/148 (36%), Gaps = 35/148 (23%)
Query: 160 QEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRR-----IPPPPPPV 214
Q V+ L AL P R A P P+ + PPAV+P +P PP
Sbjct: 853 QHAVVSPPALHNALPQQPSRPSNRAAALP-----PKPARPPAVSPALTQTPLLPQPPMAQ 907
Query: 215 PAGRL-------ATPFTAA-----MSSGQAV--PYPGLQC--------PPLPPRVGLPTQ 252
P L A P T+ + Q V P P L PPLPP Q
Sbjct: 908 PPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQ 967
Query: 253 QGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
Q Q P PPP PQ PP HQP
Sbjct: 968 QQLQQQ---PPPPPPPQPQPPPQQQHQP 992
Score = 37.7 bits (86), Expect = 0.012
Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 25/92 (27%)
Query: 192 PAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPT 251
PAP PP P + PPPPPP P Q PP PP +P
Sbjct: 750 PAPVPQQPPP--PPQQPPPPPP--------------------PQQQQQPPPPPPPPSMPQ 787
Query: 252 QQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFI 283
Q ++ + PPP P L P PG +
Sbjct: 788 Q---AAPAMKSSPPPFIATQVPVLEPQLPGSV 816
Score = 34.7 bits (78), Expect = 0.098
Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 22/110 (20%)
Query: 170 PQALAPLP-PRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMS 228
P L P P P + + P P P P+ PP + PPP P F+ +
Sbjct: 955 PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ-----PPPRPVHLQPMQFSTHI- 1008
Query: 229 SGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPH 278
Q P P Q PP PP P QQ PPP P +P + H
Sbjct: 1009 --QQPPPPQGQQPPHPP----PGQQP---------PPPQPAKPQQVIQHH 1043
Score = 34.3 bits (77), Expect = 0.13
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 6/67 (8%)
Query: 154 VKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYP-----APEASGPPAVAPRRIP 208
VK EK+ +++ + +L P PP+ PE + AP+ P P G P + P
Sbjct: 1110 VKEEKIHSPIIRSEPFSPSLRPEPPKHPE-SIKAPVHLPQRPEMKPVDVGRPVIRPPEQN 1168
Query: 209 PPPPPVP 215
PPP P
Sbjct: 1169 APPPGAP 1175
Score = 32.7 bits (73), Expect = 0.37
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Query: 231 QAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPP--LPQRPPPRLPPHQPGFI 283
Q P P Q PP PP+ P Q P PPP +PQ+ P + P FI
Sbjct: 747 QQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
Score = 31.2 bits (69), Expect = 1.1
Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 9/108 (8%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS 229
PQ L PP P+ P P P P P S PP +A P P G T ++
Sbjct: 244 PQPLQTPPPVPPQPQPP-PAPAPQPVQSHPPIIA---ATPQPVKTKKGVKRKADTTTPTT 299
Query: 230 GQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
+ P P LPP T+ G + P PP P + P
Sbjct: 300 IDPIHEP----PSLPPE-PKTTKLGQRRESSRPVKPPKKDVPDSQQHP 342
Score = 29.3 bits (64), Expect = 4.1
Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 23/107 (21%)
Query: 175 PLPPRLPELAPTAPLP--YPAPEASGPPAVAPRRIPPP-PPPVPAGRLATPFTAAMSSGQ 231
P P P+L P+ P PP V P+ PPP P P P Q
Sbjct: 224 PFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPV--------------Q 269
Query: 232 AVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPL-PQRPPPRLPP 277
+ P P + P P + T++G + + P + P PP LPP
Sbjct: 270 SHP-PIIAATPQP----VKTKKGVKRKADTTTPTTIDPIHEPPSLPP 311
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/120 (33%), Positives = 47/120 (39%), Gaps = 11/120 (9%)
Query: 170 PQALAPLPPRLPELAP--TAPLPYPAPEASGP-PAVAP----RRIPPPPPPVPAGRLATP 222
P PLPP LP +P T + P P G P VAP PPPPPP P P
Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
Query: 223 FTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPL----PQRPPPRLPPH 278
+ L PP+PP + L G+ P P P PPP LPP+
Sbjct: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY 299
Score = 52.4 bits (124), Expect = 5e-07
Identities = 42/127 (33%), Positives = 53/127 (41%), Gaps = 18/127 (14%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVP-------AGRLAT 221
+P A P PP P P P + + P +AP +PP PPP+P G A
Sbjct: 219 VPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAE 278
Query: 222 PFTAAMSSGQAVPYPGLQCPPLP------PRVGLPTQQGFSSQFVSPYPPPLPQRPPP-R 274
P + A + Q P P PPLP PR LP S PPPLP + P +
Sbjct: 279 PASPAQDA-QEPPAPP---PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ 334
Query: 275 LPPHQPG 281
PP + G
Sbjct: 335 APPQKAG 341
Score = 51.6 bits (122), Expect = 8e-07
Identities = 45/149 (30%), Positives = 58/149 (38%), Gaps = 34/149 (22%)
Query: 159 LQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEAS-GPPAVAPRRIPPPPPPVPAG 217
L + +K Q P L P+PP LP L P YP +A PA + P PPPP+P
Sbjct: 243 LSDKAVKPQLAPLHLPPIPPPLPLLPPCG---YPGLKAEPASPAQDAQEPPAPPPPLPPY 299
Query: 218 RLATPFTAAMSSGQAVPYPGLQC-----PPLPPR---VGLPTQQGFSSQFVSPYPPPLPQ 269
+P +S A P PG+ PPLPP+ P Q+ + +P PP Q
Sbjct: 300 ASCSP----RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQ 355
Query: 270 ------------------RPPPRLPPHQP 280
PPP P P
Sbjct: 356 PFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
Score = 47.0 bits (110), Expect = 2e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 19/133 (14%)
Query: 153 RVKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPP 212
R +L + G +P P PRL + AP PA P PPPPP
Sbjct: 129 RAPSPRLPNKTISGPLIP----PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPP 184
Query: 213 PVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVG-LPTQQGFSSQFVSPYPPPLPQRP 271
P+P + S + P L PP P G LP + V PPP P P
Sbjct: 185 PLP---------PPLPSSSPIKTP-LVSPPGPLTKGNLPV----VAPPVPCAPPPPPPPP 230
Query: 272 PPRLPPHQPGFIL 284
PP PP P +L
Sbjct: 231 PPTPPPLPPASVL 243
Score = 46.2 bits (108), Expect = 3e-05
Identities = 38/113 (33%), Positives = 44/113 (38%), Gaps = 12/113 (10%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRL---ATPFTAA 226
P+ P PP P P P P P P S P P + PP P+ G L A P A
Sbjct: 167 PRPNVPAPP--PPTPPPPPPPLPPPLPSSSPIKTP--LVSPPGPLTKGNLPVVAPPVPCA 222
Query: 227 MSSGQAVPYPGLQCPPLPPRVGL---PTQQGFSSQFVSPYPPPLPQRPPPRLP 276
P P PPLPP L + + + P PPPLP PP P
Sbjct: 223 PPPPPPPPPP--TPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
Score = 29.6 bits (65), Expect = 3.2
Identities = 16/41 (39%), Positives = 17/41 (41%), Gaps = 13/41 (31%)
Query: 175 PLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVP 215
P+PP P PLP P P PP PPPP P
Sbjct: 2 PVPP-----PPPPPLPPPPPPLGAPP--------PPPPSAP 29
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/116 (35%), Positives = 51/116 (43%), Gaps = 16/116 (13%)
Query: 173 LAPLPPRLP-----ELAPTAPLPYPAPEASGPPAVAPRRIPPPPP--PVPAGRLATPFTA 225
+AP+PP P +AP P P AP PP +AP +PP PP PVP G P
Sbjct: 267 IAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPP-MAP--VPPWPPMAPVPTGPPMAPVPP 323
Query: 226 AMSSGQAVPYPGL-QCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
+ P P + + PP PP LP ++P PP P P P PP P
Sbjct: 324 GPPMARVPPGPPMARVPPGPPMAPLP-----PGPPMAPLPPGPPMAPLPPGPPMAP 374
Score = 48.9 bits (115), Expect = 5e-06
Identities = 37/109 (33%), Positives = 44/109 (40%), Gaps = 14/109 (12%)
Query: 173 LAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQA 232
+AP+PP P +AP P P AP PP +AP PP PVP G +
Sbjct: 282 MAPVPPG-PRMAPVPPWPPMAPVPPWPP-MAPVPTGPPMAPVPPGPPMARVPPGPPMARV 339
Query: 233 VPYPGLQ-CPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
P P + PP PP LP P PP P P P + P P
Sbjct: 340 PPGPPMAPLPPGPPMAPLP-----------PGPPMAPLPPGPPMAPLPP 377
Score = 45.8 bits (107), Expect = 4e-05
Identities = 36/110 (32%), Positives = 44/110 (40%), Gaps = 13/110 (11%)
Query: 173 LAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQA 232
L P PR P L P P+P P PP +PP P P R+A P
Sbjct: 237 LVPQLPRPPVL-PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMA-PVPPGPRMAPV 294
Query: 233 VPYPGL-QCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPP-PRLPPHQP 280
P+P + PP PP +PT P P+P PP R+PP P
Sbjct: 295 PPWPPMAPVPPWPPMAPVPT---------GPPMAPVPPGPPMARVPPGPP 335
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/85 (35%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Query: 173 LAPLPP-----RLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPP--PVPAGRLATPFTA 225
+AP+PP +P P AP+P P A PP R+PP PP P+P G P
Sbjct: 300 MAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPP 359
Query: 226 AMSSGQAVPYPGLQCPPLPPRVGLP 250
P P + PLPPR +P
Sbjct: 360 GPPMAPLPPGPPM--APLPPRSHVP 382
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 53.5 bits (127), Expect = 2e-07
Identities = 46/125 (36%), Positives = 49/125 (39%), Gaps = 26/125 (20%)
Query: 177 PPRLPELAPTAPLPYPAPEASG---PPAVA--PRRIPPPPPPV--PAGRLATPFTAAMSS 229
PPR P L P P P P G PP +A P R PPPPV P P +
Sbjct: 236 PPR-PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP 294
Query: 230 GQAVPYPGLQCPPLPPRVGLPTQQG-------FSSQFVSPYPPPLPQRPPPRL------- 275
G P PG PP PP P QQG F + P PPL PPP L
Sbjct: 295 GPPPPVPGYGPPPGPP----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGA 350
Query: 276 PPHQP 280
PP P
Sbjct: 351 PPPAP 355
Score = 50.4 bits (119), Expect = 2e-06
Identities = 49/136 (36%), Positives = 52/136 (38%), Gaps = 30/136 (22%)
Query: 166 GQRLPQALA--------PLPPRL--------PELAPTAPLPYPAPEASGPPA--VAPRRI 207
GQ LP LA P PP L P L P P P P GPP P++
Sbjct: 256 GQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQG 315
Query: 208 PPPPP----PVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVG-----LPTQQGFSSQ 258
PPPPP P P G L P T A P PG PP P V PT G +
Sbjct: 316 PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPG--APPPAPHVNPAFFPPPTNSGMPTS 373
Query: 259 FVSPYPPPLPQ-RPPP 273
PP P RPPP
Sbjct: 374 DSRGPPPTDPYGRPPP 389
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/149 (28%), Positives = 50/149 (33%), Gaps = 46/149 (30%)
Query: 166 GQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTA 225
G R P P P P P+PA + P + P P PP P P G++ P A
Sbjct: 214 GDRFPGPAGPGGP---------PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
Query: 226 A--------------------------MSSGQAVPYPGLQCPPLPPRVGLPTQQG----- 254
+ G P PG PP PP P QQG
Sbjct: 265 GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPP----PPQQGPPPPP 320
Query: 255 --FSSQFVSPYPPPLPQRPPPRLPPHQPG 281
F + P PPL PPP LP PG
Sbjct: 321 GPFPPRPPGPLGPPLTLAPPPHLPGPPPG 349
Score = 36.6 bits (83), Expect = 0.026
Identities = 33/104 (31%), Positives = 41/104 (39%), Gaps = 19/104 (18%)
Query: 191 YPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLP 250
+P G P PPPP PAG+ TP + G P PG PP P +V P
Sbjct: 207 FPGAVPGGDRFPGPAGPGGPPPPFPAGQ--TPPRPPL--GPPGP-PGPPGPPPPGQVLPP 261
Query: 251 TQQGFSSQFVSPYPP--------------PLPQRPPPRLPPHQP 280
G ++ P PP PLP PPP +P + P
Sbjct: 262 PLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGP 305
Score = 28.9 bits (63), Expect = 5.4
Identities = 26/88 (29%), Positives = 31/88 (35%), Gaps = 14/88 (15%)
Query: 197 SGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFS 256
+GPP + R P GR F A+ G P P P PP F
Sbjct: 186 AGPPGGSSRAAFPQ-----GGRGRGRFPGAVPGGDRFPGPAGPGGPPPP---------FP 231
Query: 257 SQFVSPYPPPLPQRPPPRLPPHQPGFIL 284
+ P PP P PP P PG +L
Sbjct: 232 AGQTPPRPPLGPPGPPGPPGPPPPGQVL 259
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/112 (33%), Positives = 49/112 (43%), Gaps = 23/112 (20%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS 229
P + P PP P ++P+A P P+A P A P ++PP PP P P + + +
Sbjct: 703 PLQVPPSPPASPPMSPSAT---PPPQAPPPLAAPPLQVPPSPPASP------PMSPSATP 753
Query: 230 GQAVP----YPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
VP P LQ PP PP LP +SP P PQ PP P
Sbjct: 754 PPRVPPLLAAPPLQVPPSPP-ASLP---------MSPLAKPPPQAPPALATP 795
Score = 51.6 bits (122), Expect = 8e-07
Identities = 42/123 (34%), Positives = 48/123 (39%), Gaps = 23/123 (18%)
Query: 170 PQALAPLPP--RLPELAP------TAPLPYPAPEASGPPAVAPRRIPPPP----PPVPAG 217
P A PP LP LAP +APL P E PA P + PP P PP
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 218 RLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
+ATP A + + P GL PPL P P P PP PP + PP
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPP-----------PQAPPXLALPPLQAPP 634
Query: 278 HQP 280
P
Sbjct: 635 SPP 637
Score = 50.8 bits (120), Expect = 1e-06
Identities = 40/116 (34%), Positives = 51/116 (43%), Gaps = 18/116 (15%)
Query: 168 RLPQALAP----LPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPF 223
R+P LA +PP P P +PL P P+A PPA+A PP +P+ + P
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA--PPALA----TPPLQALPSPPASFPG 809
Query: 224 TAAMSSGQAVPYPGLQCPP--LPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPP 277
A S ++P L PP PP + P Q V P PP P PR PP
Sbjct: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPP 859
Score = 48.9 bits (115), Expect = 5e-06
Identities = 38/122 (31%), Positives = 51/122 (41%), Gaps = 16/122 (13%)
Query: 175 PLPPRLPELAPTAPLPYPAPE-----ASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS 229
P P P AP +PL P PE A+ PP P PP +P+ L+ T +
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 230 GQAVPYPGLQCPPLPPR------VGLPTQQGFSSQFV----SPY-PPPLPQRPPPRLPPH 278
+ P LQ PP PP + P+ Q ++ V +P+ PPP P P PP
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 279 QP 280
P
Sbjct: 682 SP 683
Score = 47.8 bits (112), Expect = 1e-05
Identities = 42/118 (35%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASG-PPAVAPRRIPPPPPPVPAGRLATP--FTA 225
L QA PP P AP +P P S PP+ AP + PP VP A+P +
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719
Query: 226 AMSSGQAVP---YPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQP 280
A QA P P LQ PP PP + S P PPL PP ++PP P
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPP----ASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
Score = 46.2 bits (108), Expect = 3e-05
Identities = 48/144 (33%), Positives = 55/144 (38%), Gaps = 28/144 (19%)
Query: 146 RKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASG------- 198
R AH + K + LQ + R PQ P P L P + P P SG
Sbjct: 264 RAPAHPSQPKPKGLQAL-----RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318
Query: 199 PPAVA----PRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQG 254
PP A P +PP PP LATP A S A P LQ P PP P Q
Sbjct: 319 PPDNAATPLPATLPPSPP------LATPLPLAPPSPSAP--PSLQTLPSPP--ATPPSQA 368
Query: 255 FSSQFVSPY--PPPLPQRPPPRLP 276
S P PP L PP ++P
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVP 392
Score = 46.2 bits (108), Expect = 3e-05
Identities = 44/121 (36%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPP-PPPPVPAGRLATPFTAAMS 228
P ALA P + P +PL P P+A A+ P + PP PP P LATP A +
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654
Query: 229 SGQAVPYPGLQCPPLPPRVGLPTQQGFS---SQFVSP------YPPPLPQRPPPRLPPHQ 279
A+ LQ P PP P Q FS S VSP PP PP ++PP
Sbjct: 655 ---ALAVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 280 P 280
P
Sbjct: 711 P 711
Score = 45.4 bits (106), Expect = 6e-05
Identities = 44/139 (31%), Positives = 54/139 (38%), Gaps = 23/139 (16%)
Query: 168 RLPQALAPLPPRLPELA--PTAPLPYPAPEASGPPAVAPRRIPP------PPPPVPAGRL 219
++P + PP P P AP P AP PP +P PP PPP VP
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP--SPPASPPMSPSATPPPRVPPLLA 762
Query: 220 ATPFTAAMSSGQAVPYPGLQCPP--LPPRVGLPTQQGFSSQFVS-----PYPP--PLPQ- 269
A P S ++P L PP PP + P Q S S P+ P LP
Sbjct: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Query: 270 ---RPPPRLPPHQPGFILQ 285
PPP+ PP +LQ
Sbjct: 823 PLATPPPQAPPVLAAPLLQ 841
Score = 45.1 bits (105), Expect = 7e-05
Identities = 41/143 (28%), Positives = 54/143 (37%), Gaps = 19/143 (13%)
Query: 156 IEKLQEMVLKGQRLPQALAPLPPRLPE--LAP----TAPLPYPAPEASGPPAVAPRRIPP 209
++ L + + P + +PP + LAP T P P P++AP +
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 210 PPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPP------------LPPRVGLPTQQGFSS 257
P+ L TP A QA P P PP PP + P QG S
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 258 QFVSPYPPPLPQRPPP-RLPPHQ 279
+SP P PQ PP LPP Q
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQ 631
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/122 (30%), Positives = 47/122 (38%), Gaps = 15/122 (12%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVA--PRRIPPPPPPVPAGRLATPFTAAM 227
P LAP P P T P P P + PP++ P + PP +P + P +
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP--IQVPHSLTS 397
Query: 228 SSGQAVPYP-GLQCPPLPPRVGLPTQQGFSSQFVSPYP---------PPLPQRPPPRLPP 277
S QA P P L +G PT Q S F++ P P P PP PP
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHS-FLTMSPRQTQASLTSPSRPASTPPDSPP 456
Query: 278 HQ 279
Q
Sbjct: 457 LQ 458
Score = 38.5 bits (88), Expect = 0.007
Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 15/100 (15%)
Query: 175 PLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVP 234
P+PP P+ A T P PA PP P + PP P P P A QA P
Sbjct: 316 PVPP--PDNAAT---PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 235 ---YPGLQCPP----LPPRVGLPTQQGFSSQFVSPYPPPL 267
P +Q PP +PP + +S + P PL
Sbjct: 371 SMTTPPMQAPPSLQTIPP---IQVPHSLTSPSLQAPPSPL 407
Score = 36.2 bits (82), Expect = 0.034
Identities = 40/143 (27%), Positives = 49/143 (34%), Gaps = 30/143 (20%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPP--------------PPP 212
+R P A L ++ P +P SGP A R P PP
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 213 PVPAGRLATPFTAAMSSGQ-AVPYP-GLQCPPLPP----RVGLPTQQGFSSQFVSPYP-- 264
P + A P +SS A P P G + P+PP LP S +P P
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344
Query: 265 PPLPQRP--------PPRLPPHQ 279
PP P P PP PP Q
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQ 367
Score = 36.2 bits (82), Expect = 0.034
Identities = 40/138 (28%), Positives = 48/138 (34%), Gaps = 26/138 (18%)
Query: 164 LKGQRLPQALAPLPPRLPELAPTAPLPYP-----------APEA-----SGPPAVAPRRI 207
+ G RL ALAP PP P +P++ L P PE SGP A
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA---- 922
Query: 208 PPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCP----PLPPRVGLPTQQGFSSQFVSPY 263
P P LA AA S G A P P P PP G + G + + +
Sbjct: 923 --AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 980
Query: 264 PPPLPQRPPPRLPPHQPG 281
P P P PG
Sbjct: 981 PESATPAPGALDPGPSPG 998
Score = 31.6 bits (70), Expect = 0.83
Identities = 31/126 (24%), Positives = 44/126 (34%), Gaps = 23/126 (18%)
Query: 176 LPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPP-----PVPAGRLATPFT------ 224
+ PR + + T+P + PP AP +P PP L++P T
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491
Query: 225 --AAMSSGQAVPYPGLQCPPLPPRVGL--PTQQGFSSQFVSP--------YPPPLPQRPP 272
+ S P L PPL + L P+ Q + +P PPPL
Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
Query: 273 PRLPPH 278
P PH
Sbjct: 552 PLTTPH 557
Score = 31.6 bits (70), Expect = 0.83
Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 26/127 (20%)
Query: 173 LAPLPPRLPEL--APTAPLPYPAPEASGPPAVAPRRIP--------------------PP 210
LA PP+ P + AP +P P+P AS P APRR P PP
Sbjct: 824 LATPPPQAPPVLAAPLLQVP-PSPPAS-PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 881
Query: 211 PPP--VPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLP 268
PPP P+ L+ P A SS L+ P G ++ + +P
Sbjct: 882 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 941
Query: 269 QRPPPRL 275
+ P P L
Sbjct: 942 RGPAPPL 948
Score = 30.0 bits (66), Expect = 2.4
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 1/80 (1%)
Query: 193 APEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQ 252
AP+ S A A R P P P+ +A AA + +P P P PP G
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAA-GTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 253 QGFSSQFVSPYPPPLPQRPP 272
+S+ + P P +R P
Sbjct: 209 VSSASEHSTTEPSPAARRRP 228
Score = 29.3 bits (64), Expect = 4.1
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 7/89 (7%)
Query: 192 PAPEASGPPAVAPRRIPPPPPPV-PAGRLATPFTAAMS----SGQAVPYPGLQCPPLPPR 246
PA A G P P PPPPV PA A+ + +A G P PR
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 247 VGLPTQQGFSSQFVSPYPPP--LPQRPPP 273
G G SS+ + PP +R PP
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPP 105
Score = 28.9 bits (63), Expect = 5.4
Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 25/101 (24%)
Query: 174 APLPPR--LPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQ 231
AP P LP P P P + P ++PP PP P + + +
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLL----QVPPSPPASP----------TLQAPR 856
Query: 232 AVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPP 272
P PG PR+ L ++P PPP P R P
Sbjct: 857 RPPTPGPDTSVSGPRLTLA---------LAPGPPPPPSRSP 888
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 53.5 bits (127), Expect = 2e-07
Identities = 45/143 (31%), Positives = 59/143 (41%), Gaps = 14/143 (9%)
Query: 145 KRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAP 204
+R+ RR++ E+ K +RL + RL + P AP AP PP P
Sbjct: 469 RRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRL-KAEPAAPPA--APSTPAPPPAVP 525
Query: 205 RRIPPPPPPVPAGRLATPFT-----AAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQF 259
+ +P PP P PA TP T A Q+ P PG+ P G T S F
Sbjct: 526 KELPAPPAPPPAS-APTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSF 584
Query: 260 -VSPYPPPLPQR----PPPRLPP 277
SP P LP + PP +PP
Sbjct: 585 EASPVEPQLPSKEGPEPPEEVPP 607
Score = 34.7 bits (78), Expect = 0.098
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 6/72 (8%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGP--PAVAPRRIPPPPPPVPAGRL----ATP 222
LP + LP P AP P P P + P PA+ P + PPP PA R+ A P
Sbjct: 1981 LPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARP 2040
Query: 223 FTAAMSSGQAVP 234
F A++ + P
Sbjct: 2041 FPASLGRAELHP 2052
Score = 34.3 bits (77), Expect = 0.13
Identities = 40/125 (32%), Positives = 51/125 (40%), Gaps = 25/125 (20%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATP-FTAAM 227
+ QALA L R + TAP +P + P A P P P P R + +
Sbjct: 1476 IQQALAQLSSRQGSV--TAPGGHPRHKPGLPQA------PQGPSPRPPTRYEPQRVNSGL 1527
Query: 228 SSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPP--PRL-------PPH 278
SS PG P+ VG + S VSP+PP +RPP P L PPH
Sbjct: 1528 SSDPHFEEPG----PMVRGVGGTPRD---SAGVSPFPPKRRERPPRKPELLQEESLPPPH 1580
Query: 279 QPGFI 283
GF+
Sbjct: 1581 SSGFL 1585
Score = 33.1 bits (74), Expect = 0.29
Identities = 37/114 (32%), Positives = 45/114 (39%), Gaps = 10/114 (8%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPP---PPPVPAGRLATPFTAA 226
P+ AP PP + P P P P G VA + PPP PP +L P A
Sbjct: 842 PENGAPGPP-ISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGP-EAG 899
Query: 227 MSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSP---YPPPLPQRPPPRLPP 277
+ V G Q PP PPR T+ + + S PP P PP R P
Sbjct: 900 RKPARGVGSGG-QGPP-PPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGP 951
Score = 32.7 bits (73), Expect = 0.37
Identities = 39/138 (28%), Positives = 53/138 (38%), Gaps = 22/138 (15%)
Query: 160 QEMVLKGQRLPQ---------ALAPLPPRLPELAPTAPLPYPAPEASGPP--AVAPRRI- 207
QE +LK Q+ Q P+PP P+ P PAP+A PP A+ P +
Sbjct: 652 QEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQ--PVTLGAVPAPQAPPPPPKALYPGALG 709
Query: 208 -PPPPPPV---PAGRLATPFTAAMSSGQAVPY----PGLQCPPLPPRVGLPTQQGFSSQF 259
PPP PP+ P + P+ P PG+ L PR + S F
Sbjct: 710 RPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPF 769
Query: 260 VSPYPPPLPQRPPPRLPP 277
P L +R P + P
Sbjct: 770 DRHAPAMLRERGTPPVDP 787
Score = 32.0 bits (71), Expect = 0.64
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 14/84 (16%)
Query: 183 LAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPP 242
L P+ P +P PP + P +P PPP P G P+ YP P
Sbjct: 235 LQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQG----PYR----------YPTPDGPS 280
Query: 243 LPPRVGLPTQQGFSSQFVSPYPPP 266
PRV P G + V P P
Sbjct: 281 RFPRVAGPRGSGPPMRLVEPVGRP 304
Score = 32.0 bits (71), Expect = 0.64
Identities = 38/126 (30%), Positives = 42/126 (33%), Gaps = 30/126 (23%)
Query: 182 ELAPTAPLPYPAPEASGPPA-VAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQC 240
E +P P P+ E PP V P PP P P G P S G + YP Q
Sbjct: 585 EASPVEP-QLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQG--LGYPKYQ- 640
Query: 241 PPLPPRVGLPTQQGFSSQF-----------------VSPYPP--------PLPQRPPPRL 275
LPPR Q+ Q V P PP P PQ PPP
Sbjct: 641 KSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPP 700
Query: 276 PPHQPG 281
PG
Sbjct: 701 KALYPG 706
Score = 31.2 bits (69), Expect = 1.1
Identities = 28/92 (30%), Positives = 33/92 (35%), Gaps = 21/92 (22%)
Query: 181 PELAPTAPLPYPAPEASGPPAVAPRRIPPPPP------------PVPAGRLATPFTAAMS 228
P P P A GPP P R PPP P P+P G + T +
Sbjct: 1683 PPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTD 1742
Query: 229 SGQAVPYPGLQCPPLPP--RVGLPTQQGFSSQ 258
G PG P+ P R G P Q G S +
Sbjct: 1743 RGTE---PG----PIRPSHRPGPPVQFGTSDK 1767
Score = 30.8 bits (68), Expect = 1.4
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 9/89 (10%)
Query: 191 YPAPE-ASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQ--CPPLPPRV 247
+P+P+ S PP P +P PPPP P+ + S A G+Q L R
Sbjct: 1433 WPSPKNRSRPPEERPPGLPLPPPP-PSSSAVFRLDQVIHSNPA----GIQQALAQLSSRQ 1487
Query: 248 GLPTQQGFSSQFVSPYPPPLPQRPPPRLP 276
G T G + P P PQ P PR P
Sbjct: 1488 GSVTAPGGHPRH-KPGLPQAPQGPSPRPP 1515
Score = 28.1 bits (61), Expect = 9.2
Identities = 35/125 (28%), Positives = 44/125 (35%), Gaps = 46/125 (36%)
Query: 177 PPRLPELA---------PTAPLPYPAP--EASGPPAVAPRRIPPPPPPVPAGRLATPFTA 225
PP P+LA P P P +P +A+ R PP PP P P+ A
Sbjct: 783 PPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPP------PYLA 836
Query: 226 AMSSGQAVPYPGL--QCPPLPPRVGLPTQQGFSSQFVSPYPPPLP-----------QRPP 272
+ YPG P PP P ++ P P PLP Q PP
Sbjct: 837 S--------YPGFPENGAPGPPISRFPLEE--------PGPRPLPWPPGSDEVAKIQTPP 880
Query: 273 PRLPP 277
P+ P
Sbjct: 881 PKKEP 885
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/123 (34%), Positives = 53/123 (43%), Gaps = 25/123 (20%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS 229
P + P PP P ++P+A P P+A P A P ++ PPP P LATP A+ S
Sbjct: 478 PLQVPPSPPASPPMSPSAT---PPPQAPPPLAAPPLQLAKPPPQAPPA-LATPPLQALPS 533
Query: 230 ------GQA-------VPYPGLQCPP--LPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPR 274
GQA +P L PP PP + P Q V P PP P PR
Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPR 587
Query: 275 LPP 277
PP
Sbjct: 588 RPP 590
Score = 52.4 bits (124), Expect = 5e-07
Identities = 47/121 (38%), Positives = 54/121 (44%), Gaps = 28/121 (23%)
Query: 172 ALAPL--PPRLPELAPTAPLPYPAPEASGPPAV----APRRIPPPPPPV------PAGRL 219
AL PL PP P P +PL P+P+A AV AP PPP PPV PA
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPP 459
Query: 220 ATPFTAAMSSGQAVP---YPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLP 276
+P +A QA P P LQ PP PP +S +SP P PQ PPP
Sbjct: 460 VSP--SATPPSQAPPSLAAPPLQVPPSPP----------ASPPMSPSATPPPQAPPPLAA 507
Query: 277 P 277
P
Sbjct: 508 P 508
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/143 (32%), Positives = 57/143 (39%), Gaps = 19/143 (13%)
Query: 146 RKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAP--TAPLPYPAPEASGPPAVA 203
R AH + K + LQ + R PQ P P L P ++PL P+P A+
Sbjct: 264 RAPAHPSQPKPKGLQAL-----RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318
Query: 204 PRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPP---------RVGLPTQQG 254
P P +LATP A S A P LQ P PP +G PT Q
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAP--PSLQTLPSPPATPPSQATTSLGSPTLQA 376
Query: 255 FSSQFVSPYPPPLPQRPPPRLPP 277
S SP PL PPP+ PP
Sbjct: 377 THSFLPSPPLSPL-ATPPPQAPP 398
Score = 44.3 bits (103), Expect = 1e-04
Identities = 48/145 (33%), Positives = 54/145 (37%), Gaps = 34/145 (23%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASG-PP-------AVAPRRIPP----------- 209
L QA PP P AP +P P S PP A P ++PP
Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 494
Query: 210 --PPPPVPAGRLATPFTAAMSSGQAVP---YPGLQCPPLPPRVGLPTQQGFS---SQFVS 261
PPP P A P A QA P P LQ P PP P Q FS S +S
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP-ASFPGQAPFSPSASLPMS 553
Query: 262 PYPPPLPQRPPP------RLPPHQP 280
P P PQ PP ++PP P
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPP 578
Score = 41.6 bits (96), Expect = 8e-04
Identities = 42/110 (38%), Positives = 47/110 (42%), Gaps = 17/110 (15%)
Query: 181 PELAPTAPLPYPAPEASG-PPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQ 239
P L+P A P AP A PP AP P PP P LATP A + A+ LQ
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAP---PSPPASPPLSPLATPSPQAPN---ALAVHLLQ 437
Query: 240 CPPLPPRVGLPTQQGFS---SQFVSP------YPPPLPQRPPPRLPPHQP 280
P PP P Q FS S VSP PP PP ++PP P
Sbjct: 438 APFSPP-PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/141 (26%), Positives = 53/141 (37%), Gaps = 37/141 (26%)
Query: 177 PPRLPELAPTA--------PLPYPAPEASGPPAVAPRRIPPPPPP--------------- 213
PP LP ++ PLP P S PP++ PP PP
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 377
Query: 214 ---VPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPR------VGLPTQQGFSSQFV---- 260
+P+ L+ T + A+ P LQ PP PP + P+ Q ++ V
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Query: 261 SPY-PPPLPQRPPPRLPPHQP 280
+P+ PPP P P PP P
Sbjct: 438 APFSPPPSPPVQAPFSPPASP 458
Score = 37.0 bits (84), Expect = 0.020
Identities = 39/142 (27%), Positives = 47/142 (33%), Gaps = 31/142 (21%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPP--------------PPP 212
+R P A L ++ P +P SGP A R P PP
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 213 PVPAGRLATPFTAAMSSGQ-AVPYPGL----QCPPLPPRVGLPTQQGFSSQFVSPYP--P 265
P + A P +SS A P P Q PP P P + Q +P P P
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP--ATPHSSSLTCQLATPLPLAP 342
Query: 266 PLPQRP--------PPRLPPHQ 279
P P P PP PP Q
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQ 364
Score = 36.2 bits (82), Expect = 0.034
Identities = 40/138 (28%), Positives = 48/138 (34%), Gaps = 26/138 (18%)
Query: 164 LKGQRLPQALAPLPPRLPELAPTAPLPYP-----------APEA-----SGPPAVAPRRI 207
+ G RL ALAP PP P +P++ L P PE SGP A
Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA---- 653
Query: 208 PPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCP----PLPPRVGLPTQQGFSSQFVSPY 263
P P LA AA S G A P P P PP G + G + + +
Sbjct: 654 --AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
Query: 264 PPPLPQRPPPRLPPHQPG 281
P P P PG
Sbjct: 712 PESATPAPGALDPGPSPG 729
Score = 31.6 bits (70), Expect = 0.83
Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 26/127 (20%)
Query: 173 LAPLPPRLPEL--APTAPLPYPAPEASGPPAVAPRRIP--------------------PP 210
LA PP+ P + AP +P P+P AS P APRR P PP
Sbjct: 555 LATPPPQAPPVLAAPLLQVP-PSPPAS-PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 211 PPP--VPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLP 268
PPP P+ L+ P A SS L+ P G ++ + +P
Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672
Query: 269 QRPPPRL 275
+ P P L
Sbjct: 673 RGPAPPL 679
Score = 30.0 bits (66), Expect = 2.4
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 1/80 (1%)
Query: 193 APEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQ 252
AP+ S A A R P P P+ +A AA + +P P P PP G
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAA-GTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 253 QGFSSQFVSPYPPPLPQRPP 272
+S+ + P P +R P
Sbjct: 209 VSSASEHSTTEPSPAARRRP 228
Score = 29.3 bits (64), Expect = 4.1
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 7/89 (7%)
Query: 192 PAPEASGPPAVAPRRIPPPPPPV-PAGRLATPFTAAMS----SGQAVPYPGLQCPPLPPR 246
PA A G P P PPPPV PA A+ + +A G P PR
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 247 VGLPTQQGFSSQFVSPYPPP--LPQRPPP 273
G G SS+ + PP +R PP
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPP 105
Score = 28.9 bits (63), Expect = 5.4
Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 25/101 (24%)
Query: 174 APLPPR--LPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQ 231
AP P LP P P P + P ++PP PP P + + +
Sbjct: 542 APFSPSASLPMSPLATPPPQAPPVLAAPLL----QVPPSPPASP----------TLQAPR 587
Query: 232 AVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPP 272
P PG PR+ L ++P PPP P R P
Sbjct: 588 RPPTPGPDTSVSGPRLTLA---------LAPGPPPPPSRSP 619
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/123 (34%), Positives = 53/123 (43%), Gaps = 25/123 (20%)
Query: 170 PQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSS 229
P + P PP P ++P+A P P+A P A P ++ PPP P LATP A+ S
Sbjct: 439 PLQVPPSPPASPPMSPSAT---PPPQAPPPLAAPPLQLAKPPPQAPPA-LATPPLQALPS 494
Query: 230 ------GQA-------VPYPGLQCPP--LPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPR 274
GQA +P L PP PP + P Q V P PP P PR
Sbjct: 495 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPR 548
Query: 275 LPP 277
PP
Sbjct: 549 RPP 551
Score = 52.4 bits (124), Expect = 5e-07
Identities = 47/121 (38%), Positives = 54/121 (44%), Gaps = 28/121 (23%)
Query: 172 ALAPL--PPRLPELAPTAPLPYPAPEASGPPAV----APRRIPPPPPPV------PAGRL 219
AL PL PP P P +PL P+P+A AV AP PPP PPV PA
Sbjct: 362 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPP 420
Query: 220 ATPFTAAMSSGQAVP---YPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLP 276
+P +A QA P P LQ PP PP +S +SP P PQ PPP
Sbjct: 421 VSP--SATPPSQAPPSLAAPPLQVPPSPP----------ASPPMSPSATPPPQAPPPLAA 468
Query: 277 P 277
P
Sbjct: 469 P 469
Score = 45.8 bits (107), Expect = 4e-05
Identities = 48/170 (28%), Positives = 67/170 (39%), Gaps = 40/170 (23%)
Query: 146 RKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAP--TAPLPYPAPEA----SGP 199
R AH + K + LQ + R PQ P P L P ++PL P+P A S P
Sbjct: 255 RAPAHPSQPKPKGLQAL-----RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309
Query: 200 PAVAPRRIPPPPPP------------------VPAGRLATPFTAAMSSGQAVPYPGLQCP 241
P++ PP PP +P+ L+ T + A+ P LQ P
Sbjct: 310 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 369
Query: 242 PLPPR------VGLPTQQGFSSQFV----SPY-PPPLPQRPPPRLPPHQP 280
P PP + P+ Q ++ V +P+ PPP P P PP P
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Score = 44.3 bits (103), Expect = 1e-04
Identities = 48/145 (33%), Positives = 54/145 (37%), Gaps = 34/145 (23%)
Query: 169 LPQALAPLPPRLPELAPTAPLPYPAPEASG-PP-------AVAPRRIPP----------- 209
L QA PP P AP +P P S PP A P ++PP
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455
Query: 210 --PPPPVPAGRLATPFTAAMSSGQAVP---YPGLQCPPLPPRVGLPTQQGFS---SQFVS 261
PPP P A P A QA P P LQ P PP P Q FS S +S
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP-ASFPGQAPFSPSASLPMS 514
Query: 262 PYPPPLPQRPPP------RLPPHQP 280
P P PQ PP ++PP P
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPP 539
Score = 37.0 bits (84), Expect = 0.020
Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 39/147 (26%)
Query: 167 QRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIP---------------PP- 210
+R P A L ++ P +P SGP A R P PP
Sbjct: 216 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 275
Query: 211 --PP---------PVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPP---------RVGLP 250
PP P+ + LATP +A S A P LQ P PP +G P
Sbjct: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP--PSLQTLPSPPATPPSQATTSLGSP 333
Query: 251 TQQGFSSQFVSPYPPPLPQRPPPRLPP 277
T Q S SP PL PPP+ PP
Sbjct: 334 TLQATHSFLPSPPLSPL-ATPPPQAPP 359
Score = 36.2 bits (82), Expect = 0.034
Identities = 40/138 (28%), Positives = 48/138 (34%), Gaps = 26/138 (18%)
Query: 164 LKGQRLPQALAPLPPRLPELAPTAPLPYP-----------APEA-----SGPPAVAPRRI 207
+ G RL ALAP PP P +P++ L P PE SGP A
Sbjct: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA---- 614
Query: 208 PPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCP----PLPPRVGLPTQQGFSSQFVSPY 263
P P LA AA S G A P P P PP G + G + + +
Sbjct: 615 --AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 672
Query: 264 PPPLPQRPPPRLPPHQPG 281
P P P PG
Sbjct: 673 PESATPAPGALDPGPSPG 690
Score = 31.6 bits (70), Expect = 0.83
Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 26/127 (20%)
Query: 173 LAPLPPRLPEL--APTAPLPYPAPEASGPPAVAPRRIP--------------------PP 210
LA PP+ P + AP +P P+P AS P APRR P PP
Sbjct: 516 LATPPPQAPPVLAAPLLQVP-PSPPAS-PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573
Query: 211 PPP--VPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLP 268
PPP P+ L+ P A SS L+ P G ++ + +P
Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 633
Query: 269 QRPPPRL 275
+ P P L
Sbjct: 634 RGPAPPL 640
Score = 30.0 bits (66), Expect = 2.4
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 1/80 (1%)
Query: 193 APEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQ 252
AP+ S A A R P P P+ +A AA + +P P P PP G
Sbjct: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAA-GTEVGLPRPAPSARPRPPTEGPRKS 199
Query: 253 QGFSSQFVSPYPPPLPQRPP 272
+S+ + P P +R P
Sbjct: 200 VSSASEHSTTEPSPAARRRP 219
Score = 28.9 bits (63), Expect = 5.4
Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 25/101 (24%)
Query: 174 APLPPR--LPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQ 231
AP P LP P P P + P ++PP PP P + + +
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPLL----QVPPSPPASP----------TLQAPR 548
Query: 232 AVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPP 272
P PG PR+ L ++P PPP P R P
Sbjct: 549 RPPTPGPDTSVSGPRLTLA---------LAPGPPPPPSRSP 580
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,416,634
Number of Sequences: 37866
Number of extensions: 1077790
Number of successful extensions: 25701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 649
Number of HSP's successfully gapped in prelim test: 1456
Number of HSP's that attempted gapping in prelim test: 9016
Number of HSP's gapped (non-prelim): 9079
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.