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Search of human proteins with 13375654
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13375654 PTIP-associated 1 protein [Homo sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13375654 PTIP-associated 1 protein [Homo sapiens] 513 e-146
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 53 3e-07
gi|21735415 centromere protein B [Homo sapiens] 48 7e-06
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 44 1e-04
gi|215422388 death-domain associated protein isoform a [Homo sap... 44 1e-04
gi|215422366 death-domain associated protein isoform b [Homo sap... 44 1e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 44 1e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 44 1e-04
gi|82830424 gon-4-like isoform a [Homo sapiens] 44 1e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 44 1e-04
gi|55956788 nucleolin [Homo sapiens] 43 2e-04
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 43 2e-04
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 43 2e-04
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 43 2e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 43 2e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 43 2e-04
gi|189011559 B-cell scaffold protein with ankyrin repeats 1 isof... 43 3e-04
gi|144953889 B-cell scaffold protein with ankyrin repeats 1 isof... 43 3e-04
gi|144953891 B-cell scaffold protein with ankyrin repeats 1 isof... 43 3e-04
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 43 3e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 43 3e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 43 3e-04
gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo... 42 4e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 42 4e-04
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens] 42 5e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 42 5e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 42 5e-04
gi|209862789 microtubule associated monoxygenase, calponin and L... 42 5e-04
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 42 5e-04
gi|157738619 smoothelin-like 1 [Homo sapiens] 42 5e-04
>gi|13375654 PTIP-associated 1 protein [Homo sapiens]
Length = 254
Score = 513 bits (1320), Expect = e-146
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MSLARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETERE 60
MSLARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETERE
Sbjct: 1 MSLARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETERE 60
Query: 61 GSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLA 120
GSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLA
Sbjct: 61 GSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLA 120
Query: 121 AHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDS 180
AHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDS
Sbjct: 121 AHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDS 180
Query: 181 LIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPL 240
LIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPL
Sbjct: 181 LIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPL 240
Query: 241 RSSGSSLFPRQRKY 254
RSSGSSLFPRQRKY
Sbjct: 241 RSSGSSLFPRQRKY 254
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 52.8 bits (125), Expect = 3e-07
Identities = 47/142 (33%), Positives = 61/142 (42%), Gaps = 4/142 (2%)
Query: 20 EEGEVTSGLQ-ALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
EEGE G + E G G+ E+EGEG EE E EG G EE +GE GE
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919
Query: 79 PAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPT 138
EE+ E+ EE E +G+ E + +E G E + E
Sbjct: 920 KGEEEGEEG--EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE-GEGEGEE 976
Query: 139 PEAQSEEERSDEEPEAKEEEEE 160
E + EEE + E E +E EEE
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEE 998
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 21/149 (14%)
Query: 34 EDTGGPSASAGKAEDEGEGGREETEREGSG----------GEEAQGEVPSAGGEEPAEED 83
E G G+ E+EGEG EE E EG G GEE +GE GE EE+
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951
Query: 84 SEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQS 143
+W EE E +G+ E + E G E + E E
Sbjct: 952 EGEW----EGEEEEGEGEGE------EEGEGEGEEGEGEGEEE-EGEGEGEEEEGEEEGE 1000
Query: 144 EEERSDEEPEAKEEEEEKPHMPTEFDFDD 172
EE +EE E + EEEE+ + E + ++
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029
Score = 47.0 bits (110), Expect = 2e-05
Identities = 42/141 (29%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEP 79
EEGE G + G E+EGE EE E EG G EE +GE GE
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE 982
Query: 80 AEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTP 139
EE + +EE E +G+ E + G +E + E
Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE-------EGEVEGEVE-----GEEG 1030
Query: 140 EAQSEEERSDEEPEAKEEEEE 160
E + EEE +EE E +E+E E
Sbjct: 1031 EGEGEEEEGEEEGEEREKEGE 1051
Score = 42.0 bits (97), Expect = 5e-04
Identities = 47/154 (30%), Positives = 62/154 (40%), Gaps = 17/154 (11%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAE----DEGEGGREETEREGSG------GEEAQG 69
EEG+ G + E G G+ E +EG+G REE E EG G GEE +G
Sbjct: 789 EEGDQGEGEEE-ETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG 847
Query: 70 EVPSAGGEEPAEEDSEDWCVPCSDEEVE---LPADGQPWMPPPSEIQRLYELLAAHGTLE 126
E GE EE+ E+ EE E +G+ E + E G E
Sbjct: 848 EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Query: 127 LQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEE 160
+ E E + EEE + E E +EEE E
Sbjct: 908 GEGE---GEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Score = 40.0 bits (92), Expect = 0.002
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREG-SGGEEAQGEVPSAGGEE 78
E+ E+ S E + G + S G+AED EG + T EG SG E Q E G ++
Sbjct: 621 EKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKD 680
Query: 79 PAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPT 138
+ E + E EL A+ + W E Q E H Q E R
Sbjct: 681 KGRGEME----RPGEGEKEL-AEKEEWKKRDGEEQEQKEREQGH-----QKE---RNQEM 727
Query: 139 PEAQSEEERSDEEPEA-KEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKR 197
E EE EE E +EEEEEK E +E ++ R+ + + +K
Sbjct: 728 EEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG 787
Query: 198 EARLDK 203
E D+
Sbjct: 788 EEEGDQ 793
Score = 39.3 bits (90), Expect = 0.003
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 21/135 (15%)
Query: 34 EDTGGPSASAGKAEDEGEGGREETEREG----SGGEEAQGEVPSAGGEEPAEEDSEDWCV 89
E+ G + D+GEG EETE G GGE GEV GE EE+ +
Sbjct: 778 EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE--- 834
Query: 90 PCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEE--- 146
EE E + + E + E G E + E E + EEE
Sbjct: 835 ---GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE-------EGEGEGEEEEGE 884
Query: 147 -RSDEEPEAKEEEEE 160
+EE E + EEEE
Sbjct: 885 GEGEEEGEGEGEEEE 899
Score = 38.5 bits (88), Expect = 0.006
Identities = 42/144 (29%), Positives = 57/144 (39%), Gaps = 17/144 (11%)
Query: 18 LSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGE 77
+ E GE G D G+ ++EGEG E ERE GE + E AG E
Sbjct: 727 MEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE--RAGKE 784
Query: 78 EPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPP 137
E EE+ + EE E G+ E++ E+ G E + E
Sbjct: 785 EKGEEEGDQG----EGEEEETEGRGEE-KEEGGEVEG-GEVEEGKGEREEEEE------- 831
Query: 138 TPEAQSEEERSDEEPEAKEEEEEK 161
E + EEE + E E E EEE+
Sbjct: 832 --EGEGEEEEGEGEEEEGEGEEEE 853
Score = 38.1 bits (87), Expect = 0.007
Identities = 36/146 (24%), Positives = 59/146 (40%), Gaps = 6/146 (4%)
Query: 18 LSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGRE---ETEREGSGGEEAQGEVPSA 74
L+++ EV+ G E GP +EG G E + ERE ++ +GE+
Sbjct: 630 LTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERP 689
Query: 75 GGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPR 134
G E + E+W +E+ + + E++ E HG E + E
Sbjct: 690 GEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE--EEHGEGE-EEEGDRE 746
Query: 135 RPPTPEAQSEEERSDEEPEAKEEEEE 160
E + +EE EE E + E+EE
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEE 772
Score = 37.0 bits (84), Expect = 0.017
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 17/91 (18%)
Query: 6 GHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSG-- 63
G G+ EEGEV ++ E G E+EGE EE E+EG G
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG--------EEEEGEEEGEEREKEGEGEE 1054
Query: 64 -------GEEAQGEVPSAGGEEPAEEDSEDW 87
EE +G+ G EE +D E++
Sbjct: 1055 NRRNREEEEEEEGKYQETGEEENERQDGEEY 1085
Score = 33.1 bits (74), Expect = 0.24
Identities = 42/148 (28%), Positives = 54/148 (36%), Gaps = 19/148 (12%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREET-EREGSGGE------EAQGEVP 72
EE E + E G G+ + E G+EE E EG GE E +GE
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808
Query: 73 SAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEIL 132
GGE E E EE E +G+ E + E G E + E
Sbjct: 809 EEGGEVEGGEVEEG---KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGE-- 863
Query: 133 PRRPPTPEAQSEEERSDEEPEAKEEEEE 160
E + EEE + E E +EEE E
Sbjct: 864 -------EGEGEEEGEEGEGEGEEEEGE 884
Score = 30.4 bits (67), Expect = 1.6
Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 6 GHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAE-------DEGEGGREETE 58
G G+ EEGE + E+ G + E +EGEG EE E
Sbjct: 979 GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE 1038
Query: 59 REGSGGE---EAQGEVPSAGGEEPAEEDSE 85
E G E E +GE EE EE+ +
Sbjct: 1039 GEEEGEEREKEGEGEENRRNREEEEEEEGK 1068
Score = 28.1 bits (61), Expect = 7.7
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 2/67 (2%)
Query: 21 EGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGRE-ETEREGSGGEEAQGEVPSAGGEEP 79
EGE G + E+ G G+ E+E EG E E E E GE + E G E
Sbjct: 989 EGEEEEGEEE-GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEERE 1047
Query: 80 AEEDSED 86
E + E+
Sbjct: 1048 KEGEGEE 1054
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 48.1 bits (113), Expect = 7e-06
Identities = 39/145 (26%), Positives = 60/145 (41%), Gaps = 4/145 (2%)
Query: 32 AVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPC 91
+++ G + E+E EG EE E EG EE GE G EE EE+ + V
Sbjct: 400 SLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD---VDS 456
Query: 92 SDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEI-LPRRPPTPEAQSEEERSDE 150
+EE E + Q + E + G Q E P + + S+E
Sbjct: 457 DEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEE 516
Query: 151 EPEAKEEEEEKPHMPTEFDFDDEPV 175
E + +E++E++ E D D+ PV
Sbjct: 517 EDDEEEDDEDEDDDDDEEDGDEVPV 541
Score = 28.1 bits (61), Expect = 7.7
Identities = 21/76 (27%), Positives = 30/76 (39%)
Query: 124 TLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLID 183
T L++E E + EE +EE E EEEEE+ E ++E D D
Sbjct: 398 TTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSD 457
Query: 184 RRRTPGSSARSQKREA 199
+ S+ EA
Sbjct: 458 EEEEEDEESSSEGLEA 473
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/208 (25%), Positives = 77/208 (37%), Gaps = 21/208 (10%)
Query: 4 ARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEG--------EGGRE 55
AR G ++ S P E + SG + G PSAS + +DE E E
Sbjct: 396 ARLQGTSSHSADTP---EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEE 452
Query: 56 ETEREGSGGEEAQG-EVPSAGGEEPAEEDSEDWCVPCSDEE----VELPADGQPWMPPPS 110
E E E + EE + E G E+ EED E+ D + L + + P
Sbjct: 453 EEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGK 512
Query: 111 EIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF 170
+I R G + + +L P P + E ++ E EEE E +
Sbjct: 513 QISRSSGEQQNKGRI-VSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEI 571
Query: 171 DDEPVTPKDSLIDRRRTPGSSARSQKRE 198
+ P+ S+ T SS+R Q E
Sbjct: 572 EALPLDTPSSV----ETDISSSRKQSEE 595
Score = 29.6 bits (65), Expect = 2.7
Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 18/123 (14%)
Query: 135 RPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF--------DDEPVTPKDSLI---D 183
R T + EE +EE E +EEEEE E D DDE ++ D
Sbjct: 432 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKD 491
Query: 184 RRRTPGSSAR-SQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDP-SPASPPLR 241
++P SS + S ++ K +S ++ + +I+ SL SE+P +P+S
Sbjct: 492 GDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSP-----SLLSEEPLAPSSIDAE 546
Query: 242 SSG 244
S+G
Sbjct: 547 SNG 549
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/208 (25%), Positives = 77/208 (37%), Gaps = 21/208 (10%)
Query: 4 ARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEG--------EGGRE 55
AR G ++ S P E + SG + G PSAS + +DE E E
Sbjct: 396 ARLQGTSSHSADTP---EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEE 452
Query: 56 ETEREGSGGEEAQG-EVPSAGGEEPAEEDSEDWCVPCSDEE----VELPADGQPWMPPPS 110
E E E + EE + E G E+ EED E+ D + L + + P
Sbjct: 453 EEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGK 512
Query: 111 EIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF 170
+I R G + + +L P P + E ++ E EEE E +
Sbjct: 513 QISRSSGEQQNKGRI-VSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEI 571
Query: 171 DDEPVTPKDSLIDRRRTPGSSARSQKRE 198
+ P+ S+ T SS+R Q E
Sbjct: 572 EALPLDTPSSV----ETDISSSRKQSEE 595
Score = 29.6 bits (65), Expect = 2.7
Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 18/123 (14%)
Query: 135 RPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF--------DDEPVTPKDSLI---D 183
R T + EE +EE E +EEEEE E D DDE ++ D
Sbjct: 432 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKD 491
Query: 184 RRRTPGSSAR-SQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDP-SPASPPLR 241
++P SS + S ++ K +S ++ + +I+ SL SE+P +P+S
Sbjct: 492 GDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSP-----SLLSEEPLAPSSIDAE 546
Query: 242 SSG 244
S+G
Sbjct: 547 SNG 549
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/208 (25%), Positives = 77/208 (37%), Gaps = 21/208 (10%)
Query: 4 ARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEG--------EGGRE 55
AR G ++ S P E + SG + G PSAS + +DE E E
Sbjct: 408 ARLQGTSSHSADTP---EASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEE 464
Query: 56 ETEREGSGGEEAQG-EVPSAGGEEPAEEDSEDWCVPCSDEE----VELPADGQPWMPPPS 110
E E E + EE + E G E+ EED E+ D + L + + P
Sbjct: 465 EEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGK 524
Query: 111 EIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF 170
+I R G + + +L P P + E ++ E EEE E +
Sbjct: 525 QISRSSGEQQNKGRI-VSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEI 583
Query: 171 DDEPVTPKDSLIDRRRTPGSSARSQKRE 198
+ P+ S+ T SS+R Q E
Sbjct: 584 EALPLDTPSSV----ETDISSSRKQSEE 607
Score = 29.6 bits (65), Expect = 2.7
Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 18/123 (14%)
Query: 135 RPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF--------DDEPVTPKDSLI---D 183
R T + EE +EE E +EEEEE E D DDE ++ D
Sbjct: 444 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKD 503
Query: 184 RRRTPGSSAR-SQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDP-SPASPPLR 241
++P SS + S ++ K +S ++ + +I+ SL SE+P +P+S
Sbjct: 504 GDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSP-----SLLSEEPLAPSSIDAE 558
Query: 242 SSG 244
S+G
Sbjct: 559 SNG 561
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 44.3 bits (103), Expect = 1e-04
Identities = 59/258 (22%), Positives = 97/258 (37%), Gaps = 58/258 (22%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETER---------------EGSGG 64
EEG+ +G Q E+ G + + E + EE+++ +G G
Sbjct: 1259 EEGKKRTGKQN---EENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1315
Query: 65 EEAQG------EVPSAGGEEPAEEDSEDWCVPCS--------DEEVELPADGQPWMPPPS 110
EE + EV + + EDSED S E+ + P
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1375
Query: 111 EIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF 170
E QR Y+ +++Q + E + EE+ +EE E +EEEEE+ D
Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE-------DE 1428
Query: 171 DDEPVTP--------KDSLIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTG 222
+D+ +P K D+ RT +A ++ E R ++ + +KL E I
Sbjct: 1429 NDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERR-KRIAEREREREKLREVI---- 1483
Query: 223 RDLFSLDSEDPSPASPPL 240
+ ED SP P+
Sbjct: 1484 ------EIEDASPTKCPI 1495
Score = 28.1 bits (61), Expect = 7.7
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 8/89 (8%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREE----TEREGSGGEEAQGEVPSA 74
SEE E TS LA+ + +G D E +EE +E+ S G PS
Sbjct: 26 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI 85
Query: 75 GGEEPAEEDSEDWCVPCSDEEVELPADGQ 103
+ +D + P DE V A +
Sbjct: 86 VTKYVESDDEK----PLDDETVNEDASNE 110
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 44.3 bits (103), Expect = 1e-04
Identities = 59/258 (22%), Positives = 97/258 (37%), Gaps = 58/258 (22%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETER---------------EGSGG 64
EEG+ +G Q E+ G + + E + EE+++ +G G
Sbjct: 1297 EEGKKRTGKQN---EENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1353
Query: 65 EEAQG------EVPSAGGEEPAEEDSEDWCVPCS--------DEEVELPADGQPWMPPPS 110
EE + EV + + EDSED S E+ + P
Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1413
Query: 111 EIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDF 170
E QR Y+ +++Q + E + EE+ +EE E +EEEEE+ D
Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE-------DE 1466
Query: 171 DDEPVTP--------KDSLIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTG 222
+D+ +P K D+ RT +A ++ E R ++ + +KL E I
Sbjct: 1467 NDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERR-KRIAEREREREKLREVI---- 1521
Query: 223 RDLFSLDSEDPSPASPPL 240
+ ED SP P+
Sbjct: 1522 ------EIEDASPTKCPI 1533
Score = 28.1 bits (61), Expect = 7.7
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 8/89 (8%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREE----TEREGSGGEEAQGEVPSA 74
SEE E TS LA+ + +G D E +EE +E+ S G PS
Sbjct: 26 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI 85
Query: 75 GGEEPAEEDSEDWCVPCSDEEVELPADGQ 103
+ +D + P DE V A +
Sbjct: 86 VTKYVESDDEK----PLDDETVNEDASNE 110
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 44.3 bits (103), Expect = 1e-04
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 11/111 (9%)
Query: 53 GREETEREGSGGEEAQGEVPSAGGEE--PAEEDSEDWCVPCSDEEVELPADGQPWMPPPS 110
G+ E G P GGE+ P EE+ ED+ DEE E+ + + +
Sbjct: 1429 GKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVP 1488
Query: 111 EIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEK 161
E+Q T+E + R + E +SEEE S EE EEEEE+
Sbjct: 1489 ELQE---------TMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEE 1530
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 43.9 bits (102), Expect = 1e-04
Identities = 52/231 (22%), Positives = 93/231 (40%), Gaps = 31/231 (13%)
Query: 34 EDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE-----PAEEDSEDWC 88
E T + E+E + +EE +E GGEE + E GGEE PAEE +
Sbjct: 459 EQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE----GGEEETKSPPAEEAAS--- 511
Query: 89 VPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQS-EEER 147
++E + P + P ++ E A E+++ + P EA+S E +
Sbjct: 512 ---PEKEAKSPVKEEAKSPAEAKSPEKEE---AKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 148 SDEEPEAKEEEEEKPHMPTEFDFDDEPVTP---------KDSLIDRRRTPGSSARSQKRE 198
S E+ EAK E K + +E +P K + + ++P + K E
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625
Query: 199 ARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSED---PSPASPPLRSSGSS 246
A+ + ++ K ++ ++ S + E+ P A P+++ S
Sbjct: 626 AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676
Score = 36.6 bits (83), Expect = 0.022
Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 19/178 (10%)
Query: 45 KAEDEGEGGREETE-REGSGGEEA-QGEVPSAGGEE---PAEEDSEDWCVPCSDEEVELP 99
KAE+E +TE ++ S EEA + E P EE PA E ++ V EE E
Sbjct: 841 KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE-- 898
Query: 100 ADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRP----------PTPEAQSEEERSD 149
D + P E E+ E + E+ + P P + ++ E+ D
Sbjct: 899 -DKKKVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 150 EEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLDKVLSD 207
+ E ++ EEKP + DD+ ++ + S + SS+ QK +K D
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 33.1 bits (74), Expect = 0.24
Identities = 38/207 (18%), Positives = 80/207 (38%), Gaps = 25/207 (12%)
Query: 16 APLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEG---EGGREETEREGSGGEEAQG--- 69
+P+ EE + ++ E+ P + ++E E + + E E+A+
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
Query: 70 ----EVPSAGGEEPAEEDSEDWCVPCSD--EEVELPADGQPWMPPPSEIQRLYELLAAHG 123
+V S + PA+E++ P E+ + P + P ++ + A
Sbjct: 756 AKTLDVKSPEAKTPAKEEARS---PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 124 TLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDD-------EPVT 176
+ + E+ + P E + +E +EP K EEE+ P P + D +
Sbjct: 813 EIPKKEEV---KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA 869
Query: 177 PKDSLIDRRRTPGSSARSQKREARLDK 203
PK + +++ + K EA+ ++
Sbjct: 870 PKPKVEEKKEPAVEKPKESKVEAKKEE 896
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 43.1 bits (100), Expect = 2e-04
Identities = 51/233 (21%), Positives = 96/233 (41%), Gaps = 27/233 (11%)
Query: 25 TSGLQALAVEDTGGPSASAGKAED-------EGEGGREETEREGSGGEEAQGEVPSAGGE 77
T G + A+ G + K ED + E E+ E E +E + A
Sbjct: 121 TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 180
Query: 78 EPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPP 137
PA ED +D DE+ E D + + E A G + A+++P +
Sbjct: 181 APASEDEDDE----DDEDDEDDDDDE----EDDSEEEAMETTPAKG--KKAAKVVPVKAK 230
Query: 138 TPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKR 197
+EE DE+ + ++E+++ + D DDE ++ + PG +K+
Sbjct: 231 NVAEDEDEEEDDEDEDDDDDEDDE----DDDDEDDEEEEEEEEEEPVKEAPG----KRKK 282
Query: 198 EARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPLRSSGSSLFPR 250
E K + K+ +K+E T +LF + + + + ++P L++ S +F +
Sbjct: 283 EMAKQKAAPEAKK-QKVEGTEPTTAFNLF-VGNLNFNKSAPELKTGISDVFAK 333
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 43.1 bits (100), Expect = 2e-04
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 25/192 (13%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETER--EGSGGEEAQGEV--PSAG 75
+EGE +G D PS AG+A + ++ TE+ E E++ E+ P+
Sbjct: 204 DEGEGAAG-----AGDHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAES 258
Query: 76 GE--EPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILP 133
G+ E +E+ E+ E+ + P P SE ++ G + +
Sbjct: 259 GQAVEECKEEGEE-----KQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSF 313
Query: 134 RRPPTPEAQSEEERSDEEPEAKEEEEE-KPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSA 192
R+P E ++ E++ ++EPE + EE+ K + +E E P++ P SA
Sbjct: 314 RKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQE--------PAESA 365
Query: 193 RSQKREARLDKV 204
+ A +KV
Sbjct: 366 HEPRLSAEYEKV 377
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 43.1 bits (100), Expect = 2e-04
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 25/192 (13%)
Query: 20 EEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETER--EGSGGEEAQGEV--PSAG 75
+EGE +G D PS AG+A + ++ TE+ E E++ E+ P+
Sbjct: 106 DEGEGAAG-----AGDHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAES 160
Query: 76 GE--EPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILP 133
G+ E +E+ E+ E+ + P P SE ++ G + +
Sbjct: 161 GQAVEECKEEGEE-----KQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSF 215
Query: 134 RRPPTPEAQSEEERSDEEPEAKEEEEE-KPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSA 192
R+P E ++ E++ ++EPE + EE+ K + +E E P++ P SA
Sbjct: 216 RKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQE--------PAESA 267
Query: 193 RSQKREARLDKV 204
+ A +KV
Sbjct: 268 HEPRLSAEYEKV 279
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 43.1 bits (100), Expect = 2e-04
Identities = 47/168 (27%), Positives = 71/168 (42%), Gaps = 20/168 (11%)
Query: 11 AASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDE----GEGGREETEREGSGGEE 66
A ST EEGE T+G + E +GG + G+ E E GE +E E EG G E
Sbjct: 750 AESTGEMPGEEGE-TAG-EGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807
Query: 67 AQ--GEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGT 124
+ GE+ + GE E E EL A+ ++ + + + + G
Sbjct: 808 GEDEGEIHAEDGEMKGNEGET--------ESQELSAENHG--EAKNDEKGVEDGGGSDGG 857
Query: 125 LELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDD 172
+ E E + EEE+ +EE E +EEEE+ P D+ +
Sbjct: 858 DSEEEE--EEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPE 903
Score = 34.3 bits (77), Expect = 0.11
Identities = 42/168 (25%), Positives = 66/168 (39%), Gaps = 26/168 (15%)
Query: 32 AVEDTGGPSASAGKAEDEGEGGRE----------------ETEREG-----SGGE---EA 67
AV T P + E GG+E ET EG SGGE E
Sbjct: 722 AVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEG 781
Query: 68 QGEVPSAGGEEPAEEDSEDWCVPCS--DEEVELPADGQPWMPPPSEIQRLYELLAAHGTL 125
+GE + G E E+++E + ++E E+ A+ E + HG
Sbjct: 782 EGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEA 841
Query: 126 ELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDE 173
+ + + + SEEE +EE + +EEEEE+ E + ++E
Sbjct: 842 KNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889
Score = 34.3 bits (77), Expect = 0.11
Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 8 GDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSA--SAGKAEDEGEGGREETEREGSGGE 65
G+ + + LS E + VED GG S + E+E E EE E E E
Sbjct: 823 GNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEE 882
Query: 66 EAQGEVPSAGGEEPAEEDSEDW 87
E + E G EEP S DW
Sbjct: 883 EEEEEEEEKGNEEPL---SLDW 901
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 43.1 bits (100), Expect = 2e-04
Identities = 48/200 (24%), Positives = 78/200 (39%), Gaps = 27/200 (13%)
Query: 52 GGREETEREGSGGEEAQGEVPSAGGEE------PAEEDSEDWCVPCSDEEVELPADGQPW 105
G ++ETE E SG EE + EVP GE P E + E E
Sbjct: 314 GEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE-------- 365
Query: 106 MPPPSEIQRLYELLAAHGTL---ELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKP 162
SE R +LL E + ++L R E Q E+ R EE + +E E +
Sbjct: 366 ---RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQ 422
Query: 163 HMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLD-------KVLSDMKRHKKLE 215
+ + E + L RR+ R+++ + R++ + L + +RH ++
Sbjct: 423 QEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVL 482
Query: 216 EQILRTGRDLFSLDSEDPSP 235
+Q L + + D P P
Sbjct: 483 QQQLLQEQAMLLHDHRRPHP 502
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 43.1 bits (100), Expect = 2e-04
Identities = 48/200 (24%), Positives = 78/200 (39%), Gaps = 27/200 (13%)
Query: 52 GGREETEREGSGGEEAQGEVPSAGGEE------PAEEDSEDWCVPCSDEEVELPADGQPW 105
G ++ETE E SG EE + EVP GE P E + E E
Sbjct: 314 GEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE-------- 365
Query: 106 MPPPSEIQRLYELLAAHGTL---ELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKP 162
SE R +LL E + ++L R E Q E+ R EE + +E E +
Sbjct: 366 ---RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQ 422
Query: 163 HMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLD-------KVLSDMKRHKKLE 215
+ + E + L RR+ R+++ + R++ + L + +RH ++
Sbjct: 423 QEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVL 482
Query: 216 EQILRTGRDLFSLDSEDPSP 235
+Q L + + D P P
Sbjct: 483 QQQLLQEQAMLLHDHRRPHP 502
>gi|189011559 B-cell scaffold protein with ankyrin repeats 1 isoform
3 [Homo sapiens]
Length = 652
Score = 42.7 bits (99), Expect = 3e-04
Identities = 43/146 (29%), Positives = 60/146 (41%), Gaps = 23/146 (15%)
Query: 45 KAEDEGEGGREETEREGSGGEEAQG----EVPSAGGEEPAEEDSEDWCV--PCSDEE--- 95
K + G E E EG G + G P G E +E+ +D V P +D E
Sbjct: 308 KTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNS 367
Query: 96 VELPADGQPWMPPPSEIQRLYELLAAHGTL-----ELQAEILP-------RRPPTPEAQS 143
E +P +PPP + ++L H TL E Q E R+ E +
Sbjct: 368 QEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKG 427
Query: 144 EEERSDEEPEAKEEEEEKPHMPTEFD 169
E+E+ +EE E EEEE P+ E D
Sbjct: 428 EKEKKEEEKEQ--EEEEDPYTFAEID 451
>gi|144953889 B-cell scaffold protein with ankyrin repeats 1 isoform
2 [Homo sapiens]
Length = 755
Score = 42.7 bits (99), Expect = 3e-04
Identities = 43/146 (29%), Positives = 60/146 (41%), Gaps = 23/146 (15%)
Query: 45 KAEDEGEGGREETEREGSGGEEAQG----EVPSAGGEEPAEEDSEDWCV--PCSDEE--- 95
K + G E E EG G + G P G E +E+ +D V P +D E
Sbjct: 411 KTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNS 470
Query: 96 VELPADGQPWMPPPSEIQRLYELLAAHGTL-----ELQAEILP-------RRPPTPEAQS 143
E +P +PPP + ++L H TL E Q E R+ E +
Sbjct: 471 QEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKG 530
Query: 144 EEERSDEEPEAKEEEEEKPHMPTEFD 169
E+E+ +EE E EEEE P+ E D
Sbjct: 531 EKEKKEEEKEQ--EEEEDPYTFAEID 554
>gi|144953891 B-cell scaffold protein with ankyrin repeats 1 isoform
1 [Homo sapiens]
Length = 785
Score = 42.7 bits (99), Expect = 3e-04
Identities = 43/146 (29%), Positives = 60/146 (41%), Gaps = 23/146 (15%)
Query: 45 KAEDEGEGGREETEREGSGGEEAQG----EVPSAGGEEPAEEDSEDWCV--PCSDEE--- 95
K + G E E EG G + G P G E +E+ +D V P +D E
Sbjct: 441 KTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNS 500
Query: 96 VELPADGQPWMPPPSEIQRLYELLAAHGTL-----ELQAEILP-------RRPPTPEAQS 143
E +P +PPP + ++L H TL E Q E R+ E +
Sbjct: 501 QEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKG 560
Query: 144 EEERSDEEPEAKEEEEEKPHMPTEFD 169
E+E+ +EE E EEEE P+ E D
Sbjct: 561 EKEKKEEEKEQ--EEEEDPYTFAEID 584
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 42.7 bits (99), Expect = 3e-04
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 38/219 (17%)
Query: 39 PSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVEL 98
P K E+E + EE E EG + A EVP+A + + + P +EE E
Sbjct: 1218 PLPEERKEEEEMQAEAEEAE-EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEE- 1275
Query: 99 PADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPE------AQSEEERSDEEP 152
P SE QR E E Q E+ P E AQ+++ +D+E
Sbjct: 1276 -------KPRVSEEQRQSE--------EEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 153 EAKEEEEEKPHM---PTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLDK------ 203
+ E +K + PT D +EP ++S +D K E LD
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGV-QESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Query: 204 -----VLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPAS 237
V M + E+ T +L L E+ P S
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHS 1418
Score = 35.4 bits (80), Expect = 0.048
Identities = 45/221 (20%), Positives = 82/221 (37%), Gaps = 24/221 (10%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
+EEGE + + S+++ + E + EE E+ E+ Q E EE
Sbjct: 1236 AEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE 1295
Query: 79 PAEEDSEDWCVPCS---DEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRR 135
P E+ ED + D + + DG T + + E P R
Sbjct: 1296 PEPEEEEDAAAETAQNDDHDADDEDDGH-----------------LESTKKKELEEQPTR 1338
Query: 136 PPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQ 195
E +E + K E+ K TE D ++E + S++ + S
Sbjct: 1339 EDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQM--AGSEDDH 1396
Query: 196 KREARLDKVLSDMKRHKKL--EEQILRTGRDLFSLDSEDPS 234
+ ++ + L ++K +++ E L T + + SL E+ S
Sbjct: 1397 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESS 1437
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 42.7 bits (99), Expect = 3e-04
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 38/219 (17%)
Query: 39 PSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVEL 98
P K E+E + EE E EG + A EVP+A + + + P +EE E
Sbjct: 1218 PLPEERKEEEEMQAEAEEAE-EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEE- 1275
Query: 99 PADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPE------AQSEEERSDEEP 152
P SE QR E E Q E+ P E AQ+++ +D+E
Sbjct: 1276 -------KPRVSEEQRQSE--------EEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 153 EAKEEEEEKPHM---PTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLDK------ 203
+ E +K + PT D +EP ++S +D K E LD
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGV-QESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Query: 204 -----VLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPAS 237
V M + E+ T +L L E+ P S
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHS 1418
Score = 35.4 bits (80), Expect = 0.048
Identities = 45/221 (20%), Positives = 82/221 (37%), Gaps = 24/221 (10%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
+EEGE + + S+++ + E + EE E+ E+ Q E EE
Sbjct: 1236 AEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE 1295
Query: 79 PAEEDSEDWCVPCS---DEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRR 135
P E+ ED + D + + DG T + + E P R
Sbjct: 1296 PEPEEEEDAAAETAQNDDHDADDEDDGH-----------------LESTKKKELEEQPTR 1338
Query: 136 PPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQ 195
E +E + K E+ K TE D ++E + S++ + S
Sbjct: 1339 EDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQM--AGSEDDH 1396
Query: 196 KREARLDKVLSDMKRHKKL--EEQILRTGRDLFSLDSEDPS 234
+ ++ + L ++K +++ E L T + + SL E+ S
Sbjct: 1397 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESS 1437
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 42.7 bits (99), Expect = 3e-04
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 38/219 (17%)
Query: 39 PSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVEL 98
P K E+E + EE E EG + A EVP+A + + + P +EE E
Sbjct: 1218 PLPEERKEEEEMQAEAEEAE-EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEE- 1275
Query: 99 PADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPE------AQSEEERSDEEP 152
P SE QR E E Q E+ P E AQ+++ +D+E
Sbjct: 1276 -------KPRVSEEQRQSE--------EEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 153 EAKEEEEEKPHM---PTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLDK------ 203
+ E +K + PT D +EP ++S +D K E LD
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGV-QESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Query: 204 -----VLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPAS 237
V M + E+ T +L L E+ P S
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHS 1418
Score = 35.4 bits (80), Expect = 0.048
Identities = 45/221 (20%), Positives = 82/221 (37%), Gaps = 24/221 (10%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
+EEGE + + S+++ + E + EE E+ E+ Q E EE
Sbjct: 1236 AEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE 1295
Query: 79 PAEEDSEDWCVPCS---DEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRR 135
P E+ ED + D + + DG T + + E P R
Sbjct: 1296 PEPEEEEDAAAETAQNDDHDADDEDDGH-----------------LESTKKKELEEQPTR 1338
Query: 136 PPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQ 195
E +E + K E+ K TE D ++E + S++ + S
Sbjct: 1339 EDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQM--AGSEDDH 1396
Query: 196 KREARLDKVLSDMKRHKKL--EEQILRTGRDLFSLDSEDPS 234
+ ++ + L ++K +++ E L T + + SL E+ S
Sbjct: 1397 EEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESS 1437
>gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo
sapiens]
Length = 674
Score = 42.4 bits (98), Expect = 4e-04
Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 31/128 (24%)
Query: 43 AGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPA-- 100
+G+A +E E E+ +E GE A G SA + P + WC P +EE E+ A
Sbjct: 264 SGEASEEKE---EKAHKETGKGEAAPGPQSSAPAQRPQLKSW--WCQPSDEEEGEVKALG 318
Query: 101 ----DGQ----PWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEP 152
DG+ P +PPPS + + T E E+E DE+
Sbjct: 319 AAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEE----------------EEDEEEDEDS 362
Query: 153 EAKEEEEE 160
++ +EEE
Sbjct: 363 DSGSDEEE 370
Score = 35.0 bits (79), Expect = 0.063
Identities = 34/133 (25%), Positives = 51/133 (38%), Gaps = 28/133 (21%)
Query: 47 EDEGEGGREETEREGSGGEEAQGE------VPSAG----------GEEPAEEDSEDWCVP 90
+ E E EE E SG +E +GE P+ G GE+ EE+ ED
Sbjct: 349 DTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTG 408
Query: 91 CSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDE 150
+++E E A+ PP S + + T E + E + E++ D+
Sbjct: 409 SAEDERE--AETSASTPPASAFLKAWVYRPGEDTEEEEDEDV----------DSEDKEDD 456
Query: 151 EPEAKEEEEEKPH 163
A E E PH
Sbjct: 457 SEAALGEAESDPH 469
Score = 28.9 bits (63), Expect = 4.5
Identities = 42/168 (25%), Positives = 61/168 (36%), Gaps = 16/168 (9%)
Query: 2 SLARGHGDTAAS-TAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETERE 60
S+ RG G A APLS +L + G + G+ + E EG EE
Sbjct: 125 SVPRGQGSQFADGQRAPLSP---------SLLIRTLQGSDKNPGEEKAEEEGVAEEEGVN 175
Query: 61 GSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLA 120
+ E A EE EE + S + + W+ P E E A
Sbjct: 176 KFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGE----EENQA 231
Query: 121 AHGTLELQAEILPRRPPTPEAQSEEERSDE--EPEAKEEEEEKPHMPT 166
+++ + +P + + RS E EA EE+EEK H T
Sbjct: 232 TEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKET 279
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 42.4 bits (98), Expect = 4e-04
Identities = 55/199 (27%), Positives = 72/199 (36%), Gaps = 34/199 (17%)
Query: 9 DTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGS------ 62
+T A +PLSEE + G S E + G E T E S
Sbjct: 537 ETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLL 596
Query: 63 -----GGEEAQGEVPSAGGEE--------PAEEDSEDWCVPCSDEEVELPADGQPWMPPP 109
EEA EV EE PAEE + P ++ E PA+ QP PP
Sbjct: 597 AATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE---EAPAEVQP--PPA 651
Query: 110 SEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFD 169
E + A E AE+ P PP EA +E + E EE H P
Sbjct: 652 EEAPAEVQPPPAE---EAPAEVQP--PPAEEAPAEVQSLPAEETPIEETLAAVHSPPA-- 704
Query: 170 FDDEPVTPKDSLIDRRRTP 188
DD P +++ +D+ P
Sbjct: 705 -DDVPA--EEASVDKHSPP 720
Score = 30.4 bits (67), Expect = 1.6
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 2/131 (1%)
Query: 39 PSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVEL 98
P A A A E + E + E E+ EE + +P S EE
Sbjct: 301 PDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPS 360
Query: 99 PADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEE- 157
+PPP+E ELL + Q + +P E EE + EP EE
Sbjct: 361 EEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEET 420
Query: 158 -EEEKPHMPTE 167
+ +P +P E
Sbjct: 421 LADVQPLLPEE 431
>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
Length = 110
Score = 42.0 bits (97), Expect = 5e-04
Identities = 25/59 (42%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 32 AVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQG----EVPSAGGEEPAEEDSED 86
A E+ G A E+E EGG EE E E GEE G E SA G+ AE+D +D
Sbjct: 39 ANEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDD 97
Score = 34.3 bits (77), Expect = 0.11
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 9 DTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEG---EGGREETEREGSGGE 65
D A T++ ++ + ++ + + + G + + G A +E E E E E GGE
Sbjct: 3 DAAVDTSSEITTK-DLKEKKEVVEEAENGRDAPANGNANEENGEQEADNEVDEEEEEGGE 61
Query: 66 EAQGEVPSAGGEEPAEEDSE 85
E + E G EE +ED E
Sbjct: 62 EEEEEEEGDGEEEDGDEDEE 81
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 42.0 bits (97), Expect = 5e-04
Identities = 52/210 (24%), Positives = 83/210 (39%), Gaps = 25/210 (11%)
Query: 21 EGEVTSGLQALAVEDTGGPSASAGKAEDEG---EGGREETEREGSGGE---EAQGEVPSA 74
E E G + ED G A + +AE+ G EG E+ E E GE EA+GE A
Sbjct: 526 EKEEEEGQEEEEEEDEG---AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 582
Query: 75 GGEEPAEEDSEDWCVP---CSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEI 131
E+ EE SE+ +D +VE P + +P ++ + E
Sbjct: 583 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 642
Query: 132 LPRRP-----PTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRR 186
+P+ P +P +S E + P +K EEK P P +P + +
Sbjct: 643 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV-------PKSPVEEAKSKAE 695
Query: 187 TPGSSARSQKREARLDKVLSDMKRHKKLEE 216
G + ++ E + + + K KK E+
Sbjct: 696 V-GKGEQKEEEEKEVKEAPKEEKVEKKEEK 724
Score = 35.8 bits (81), Expect = 0.037
Identities = 40/186 (21%), Positives = 75/186 (40%), Gaps = 7/186 (3%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
+EE E + V P + E EG +EE E + EE +G E
Sbjct: 492 AEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEG 551
Query: 79 PAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTL-ELQAEILPRRP- 136
+E++ EE E A+ + E +++ E T EL A+ +P
Sbjct: 552 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 611
Query: 137 ----PTPEAQSEEERSDEEPEAKEEEEEKPHMP-TEFDFDDEPVTPKDSLIDRRRTPGSS 191
P P++ EE+ P++ EE+ K +P + + + PK + ++ ++P S
Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSK 671
Query: 192 ARSQKR 197
+ +++
Sbjct: 672 SPVEEK 677
Score = 35.4 bits (80), Expect = 0.048
Identities = 28/129 (21%), Positives = 54/129 (41%), Gaps = 5/129 (3%)
Query: 126 ELQAEILPRRPPTPEAQSEE----ERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSL 181
E+ A+ P + PE + EE E +E E +E+E K E + E + K+
Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 564
Query: 182 IDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPLR 241
+ A ++ EA+ +K + + +E+++ + ++ P P S P+
Sbjct: 565 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS-PVE 623
Query: 242 SSGSSLFPR 250
G S P+
Sbjct: 624 EKGKSPVPK 632
Score = 34.3 bits (77), Expect = 0.11
Identities = 53/232 (22%), Positives = 84/232 (36%), Gaps = 45/232 (19%)
Query: 21 EGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPA 80
E +T+ + LAV +A + E+E E EE + S + EV GE+
Sbjct: 470 EEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE 529
Query: 81 EEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPE 140
EE E+ +EE E Q A G E + E
Sbjct: 530 EEGQEE-----EEEEDEGAKSDQ----------------AEEGGSEKEGSSEKEEGEQEE 568
Query: 141 AQSEEERSDEEPEAKEEE--EEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKRE 198
++E E EE EAKEE+ EEK +E T ++ + D + A+S +
Sbjct: 569 GETEAEAEGEEAEAKEEKKVEEK---------SEEVATKEELVADAKVEKPEKAKSPVPK 619
Query: 199 ARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPLRSSGSSLFPR 250
+ +++ +EE+ + P P S P+ G S P+
Sbjct: 620 SPVEEKGKSPVPKSPVEEK------------GKSPVPKS-PVEEKGKSPVPK 658
Score = 30.0 bits (66), Expect = 2.0
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
SEE G + ED GK E E +ET+ +GSG EE +G V +
Sbjct: 783 SEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE-----QETKEKGSGREEEKGVVTNGLDLS 837
Query: 79 PAEE 82
PA+E
Sbjct: 838 PADE 841
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 42.0 bits (97), Expect = 5e-04
Identities = 52/210 (24%), Positives = 83/210 (39%), Gaps = 25/210 (11%)
Query: 21 EGEVTSGLQALAVEDTGGPSASAGKAEDEG---EGGREETEREGSGGE---EAQGEVPSA 74
E E G + ED G A + +AE+ G EG E+ E E GE EA+GE A
Sbjct: 150 EKEEEEGQEEEEEEDEG---AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 206
Query: 75 GGEEPAEEDSEDWCVP---CSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEI 131
E+ EE SE+ +D +VE P + +P ++ + E
Sbjct: 207 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 266
Query: 132 LPRRP-----PTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRR 186
+P+ P +P +S E + P +K EEK P P +P + +
Sbjct: 267 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV-------PKSPVEEAKSKAE 319
Query: 187 TPGSSARSQKREARLDKVLSDMKRHKKLEE 216
G + ++ E + + + K KK E+
Sbjct: 320 V-GKGEQKEEEEKEVKEAPKEEKVEKKEEK 348
Score = 35.8 bits (81), Expect = 0.037
Identities = 40/186 (21%), Positives = 75/186 (40%), Gaps = 7/186 (3%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
+EE E + V P + E EG +EE E + EE +G E
Sbjct: 116 AEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEG 175
Query: 79 PAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTL-ELQAEILPRRP- 136
+E++ EE E A+ + E +++ E T EL A+ +P
Sbjct: 176 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 235
Query: 137 ----PTPEAQSEEERSDEEPEAKEEEEEKPHMP-TEFDFDDEPVTPKDSLIDRRRTPGSS 191
P P++ EE+ P++ EE+ K +P + + + PK + ++ ++P S
Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSK 295
Query: 192 ARSQKR 197
+ +++
Sbjct: 296 SPVEEK 301
Score = 35.4 bits (80), Expect = 0.048
Identities = 28/129 (21%), Positives = 54/129 (41%), Gaps = 5/129 (3%)
Query: 126 ELQAEILPRRPPTPEAQSEE----ERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSL 181
E+ A+ P + PE + EE E +E E +E+E K E + E + K+
Sbjct: 129 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 188
Query: 182 IDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPLR 241
+ A ++ EA+ +K + + +E+++ + ++ P P S P+
Sbjct: 189 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS-PVE 247
Query: 242 SSGSSLFPR 250
G S P+
Sbjct: 248 EKGKSPVPK 256
Score = 34.3 bits (77), Expect = 0.11
Identities = 53/232 (22%), Positives = 84/232 (36%), Gaps = 45/232 (19%)
Query: 21 EGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPA 80
E +T+ + LAV +A + E+E E EE + S + EV GE+
Sbjct: 94 EEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEE 153
Query: 81 EEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPE 140
EE E+ +EE E Q A G E + E
Sbjct: 154 EEGQEE-----EEEEDEGAKSDQ----------------AEEGGSEKEGSSEKEEGEQEE 192
Query: 141 AQSEEERSDEEPEAKEEE--EEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKRE 198
++E E EE EAKEE+ EEK +E T ++ + D + A+S +
Sbjct: 193 GETEAEAEGEEAEAKEEKKVEEK---------SEEVATKEELVADAKVEKPEKAKSPVPK 243
Query: 199 ARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPLRSSGSSLFPR 250
+ +++ +EE+ + P P S P+ G S P+
Sbjct: 244 SPVEEKGKSPVPKSPVEEK------------GKSPVPKS-PVEEKGKSPVPK 282
Score = 30.0 bits (66), Expect = 2.0
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 19 SEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEE 78
SEE G + ED GK E E +ET+ +GSG EE +G V +
Sbjct: 407 SEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE-----QETKEKGSGREEEKGVVTNGLDLS 461
Query: 79 PAEE 82
PA+E
Sbjct: 462 PADE 465
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 42.0 bits (97), Expect = 5e-04
Identities = 66/252 (26%), Positives = 93/252 (36%), Gaps = 48/252 (19%)
Query: 11 AASTAAPLSEEGEVTSGLQALAVEDTGG-PSASA--------GKAEDEGEGGREETEREG 61
++S+ + + EEGE L D GG P A GK+E+E E + G
Sbjct: 933 SSSSESEMEEEGEEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSF----G 988
Query: 62 SGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAA 121
G EE + E EE EE+ ED+ +EE E G QRL +++ A
Sbjct: 989 PGNEEEEEEE-----EEYEEEEEEDY----DEEEEESSEAGN---------QRLQQVMHA 1030
Query: 122 HGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSL 181
LE+QA++ + EEER E+ E D D EP +
Sbjct: 1031 ADPLEIQADV---HWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEA 1087
Query: 182 IDRRRTPGSSARSQKREARLDKVLSDMKRHKKL-------EEQILRTGRDLFSLDSEDPS 234
+ PG + + SD R +L E LR D E+
Sbjct: 1088 AE-DGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSED------EEKL 1140
Query: 235 PASPPLRSSGSS 246
PASP + G S
Sbjct: 1141 PASPKHQERGPS 1152
Score = 41.6 bits (96), Expect = 7e-04
Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 22/117 (18%)
Query: 55 EETERE-------GSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPAD---GQP 104
EET+ E +G EE +V S+ E EE+ E+ +EE LP G P
Sbjct: 911 EETQAEHNLSSVLDTGAEE---DVASSSSESEMEEEGEE-----EEEEPRLPPSDLGGVP 962
Query: 105 WMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEK 161
W E R++ LL EL+A E + EEE +EE E +EEEE+
Sbjct: 963 W----KEAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEE 1015
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 42.0 bits (97), Expect = 5e-04
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 6/144 (4%)
Query: 34 EDTGGPSASAGKAED-EGEGGREETEREGSGGEEAQGEVPSAGGEEPAE----EDSEDWC 88
E G P A+ G+AE EG G EE R + +EA G P G E A E
Sbjct: 26 ERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEA 85
Query: 89 VPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERS 148
+ E E+P G+ +++ A G +A+ P PE Q E E+
Sbjct: 86 EEGAPEGAEVPQGGEE-TSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQR 144
Query: 149 DEEPEAKEEEEEKPHMPTEFDFDD 172
E PE E + E D
Sbjct: 145 PEVPEGSASGEAGDSVDAEGPLGD 168
Score = 35.8 bits (81), Expect = 0.037
Identities = 50/161 (31%), Positives = 60/161 (37%), Gaps = 23/161 (14%)
Query: 8 GDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAG-KAEDEG-EGGREETEREGSGGE 65
G P EG + A AV++ GG G +AE G G ETE E E
Sbjct: 32 GAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPE 91
Query: 66 EAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTL 125
A EVP GGEE + + P + E P E QR E AA
Sbjct: 92 GA--EVPQ-GGEETSGAQQVEGASPGRGAQGE----------PRGEAQREPEDSAAPERQ 138
Query: 126 ELQAEILPRRPPTPEAQSEEERSD----EEPEAKEEEEEKP 162
E +AE +RP PE + E D E P E E P
Sbjct: 139 E-EAE---QRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGP 175
Score = 35.4 bits (80), Expect = 0.048
Identities = 44/159 (27%), Positives = 58/159 (36%), Gaps = 40/159 (25%)
Query: 29 QALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVP-------SAGGEEP-- 79
+ +A G P A AE GE G E EG G E E P AGG P
Sbjct: 8 EGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDR 67
Query: 80 -------------AEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLE 126
E ++E+ + E E+P G+ E ++ A
Sbjct: 68 GPEAEARGTRGAHGETEAEEG----APEGAEVPQGGE-------ETSGAQQVEGASPGRG 116
Query: 127 LQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMP 165
Q E P EAQ E E S PE +EE E++P +P
Sbjct: 117 AQGE------PRGEAQREPEDS-AAPERQEEAEQRPEVP 148
Score = 29.6 bits (65), Expect = 2.7
Identities = 43/165 (26%), Positives = 55/165 (33%), Gaps = 23/165 (13%)
Query: 4 ARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSG 63
A G A + + G+ + QA A+E G SA GR E
Sbjct: 282 AEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESA-----------GRSPGELAWDA 330
Query: 64 GEEAQGEVPSA-GGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAH 122
EEA EVP G EE A D+ +D + DG P E +R +
Sbjct: 331 AEEA--EVPGVKGSEEAAPGDAR------ADAGEDRVGDGPQQEPGEDEERR---ERSPE 379
Query: 123 GTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTE 167
G E +A P E R EPEA+ P E
Sbjct: 380 GPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAE 424
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 42.0 bits (97), Expect = 5e-04
Identities = 52/233 (22%), Positives = 89/233 (38%), Gaps = 19/233 (8%)
Query: 9 DTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQ 68
+T + ++E SG Q A + G + G+A E + E++RE G E+A+
Sbjct: 51 ETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEV-KVESQREAGGKEDAE 109
Query: 69 GEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQ 128
E+ GE+ +E P + + + ++ E A +
Sbjct: 110 AELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQK 169
Query: 129 AEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTP 188
A+ R P P+A EEE D + ++EE ++ TE PK+ D
Sbjct: 170 ADANDRDKPEPKATVEEE--DAKTASQEETGQRKECSTE---------PKEKATDEEAKA 218
Query: 189 GSSARSQKREARLDKVLSDMK---RHKKLEEQILRTGRDLFSLDSEDPSPASP 238
S + EA+ + D K +H EE + + D+E+ P SP
Sbjct: 219 ESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAE----DAEEAEPGSP 267
Score = 32.3 bits (72), Expect = 0.41
Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 9/150 (6%)
Query: 23 EVTSGLQALAVEDTGGPSASAGKAEDEGEGGREE---TEREGSGGEEAQGEVPSAGGEEP 79
E + Q VED ++E + G +E + E EEA+ PS E+
Sbjct: 215 EAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQD 274
Query: 80 AEEDSEDWC--VPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPP 137
E++ E +P S EE G+ + + +A+ T +E P P
Sbjct: 275 VEKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGP--DCVASGQTSPSASESSPSDVP 332
Query: 138 --TPEAQSEEERSDEEPEAKEEEEEKPHMP 165
PE+ S E+ ++ PE + +P P
Sbjct: 333 QSPPESPSSGEKKEKAPERRVSAPARPRGP 362
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.126 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,197,337
Number of Sequences: 37866
Number of extensions: 819140
Number of successful extensions: 11580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 301
Number of HSP's successfully gapped in prelim test: 626
Number of HSP's that attempted gapping in prelim test: 5979
Number of HSP's gapped (non-prelim): 3474
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.