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Search of human proteins with 13324688
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13324688 bromodomain and WD repeat domain containing 2 [Homo
sapiens]
(1224 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13324688 bromodomain and WD repeat domain containing 2 [Homo ... 2462 0.0
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 42 0.004
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 42 0.004
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 42 0.004
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 42 0.004
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 41 0.006
gi|19913367 transducin beta-like 1Y [Homo sapiens] 41 0.006
gi|19913365 transducin beta-like 1Y [Homo sapiens] 41 0.006
gi|15150805 transducin beta-like 1Y [Homo sapiens] 41 0.006
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 41 0.008
gi|217330644 WD repeat domain 12 protein [Homo sapiens] 40 0.018
gi|8922735 elongator protein 2 [Homo sapiens] 40 0.018
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 40 0.018
gi|83716024 kinesin family member 21B [Homo sapiens] 40 0.018
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 38 0.052
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 38 0.052
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 38 0.052
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 37 0.12
gi|16117783 beta-transducin repeat containing protein isoform 1 ... 37 0.12
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 37 0.12
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 37 0.12
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 37 0.12
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 37 0.15
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 37 0.15
gi|55769546 PAK1 interacting protein 1 [Homo sapiens] 37 0.15
gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] 36 0.20
gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] 36 0.20
gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] 36 0.20
gi|14149696 SEC31 homolog B [Homo sapiens] 36 0.26
gi|94400919 WD repeat domain 90 [Homo sapiens] 36 0.26
>gi|13324688 bromodomain and WD repeat domain containing 2 [Homo
sapiens]
Length = 1224
Score = 2462 bits (6381), Expect = 0.0
Identities = 1224/1224 (100%), Positives = 1224/1224 (100%)
Query: 1 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH 60
MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH
Sbjct: 1 MLPYTVNFKVSARTLTGALNAHNKAAVDWGWQGLIAYGCHSLVVVIDSITAQTLQVLEKH 60
Query: 61 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ 120
KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ
Sbjct: 61 KADVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQ 120
Query: 121 WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE 180
WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE
Sbjct: 121 WLWNQDASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSE 180
Query: 181 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE 240
GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE
Sbjct: 181 GIVFISDFSPSKPPSGPGKKVYISSPHSSPAHNKLATATGAKKALNKVKILITQEKPSAE 240
Query: 241 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR 300
FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR
Sbjct: 241 FITLNDCLQLAYLPSKRNHMLLLYPREILILDLEVNQTVGVIAIERTGVPFLQVIPCFQR 300
Query: 301 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS 360
DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS
Sbjct: 301 DGLFCLHENGCITLRVRRSYNNIFTTSNEEPDPDPVQELTYDLRSQCDAIRVTKTVRPFS 360
Query: 361 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN 420
MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN
Sbjct: 361 MVCCPVNENAAALVVSDGRVMIWELKSAVCNRNSRNSSSGVSPLYSPVSFCGIPVGVLQN 420
Query: 421 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN 480
KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN
Sbjct: 421 KLPDLSLDNMIGQSAIAGEEHPRGSILREVHLKFLLTGLLSGLPAPQFAIRMCPPLTTKN 480
Query: 481 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM 540
IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM
Sbjct: 481 IKMYQPLLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNM 540
Query: 541 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC 600
GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC
Sbjct: 541 GLVRNELQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTC 600
Query: 601 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL 660
TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL
Sbjct: 601 TLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTELSIVESSVISLL 660
Query: 661 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG 720
QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG
Sbjct: 661 QEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDGSMGSITCIAWKG 720
Query: 721 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK 780
DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK
Sbjct: 721 DTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTK 780
Query: 781 EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP 840
EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP
Sbjct: 781 EVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSACFRMDEQELTEP 840
Query: 841 VWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKK 900
VWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKK
Sbjct: 841 VWCPYLLVPRASLALKAFLLHQPWNGQYSLDISHVDYPENEEIKNLLQEQLNSLSNDIKK 900
Query: 901 LLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLS 960
LLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLS
Sbjct: 901 LLLDPEFTLLQRCLLVSRLYGDESELHFWTVAAHYLHSLSQEKSASTTAPKEAAPRDKLS 960
Query: 961 NPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLET 1020
NPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLET
Sbjct: 961 NPLDICYDVLCENAYFQKFQLERVNLQEVKRSTYDHTRKCTDQLLLLGQTDRAVQLLLET 1020
Query: 1021 SADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADAC 1080
SADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADAC
Sbjct: 1021 SADNQHYYCDSLKACLVTTVTSSGPSQSTIKLVATNMIANGKLAEGVQLLCLIDKAADAC 1080
Query: 1081 RYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSV 1140
RYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSV
Sbjct: 1081 RYLQTYGEWNRAAWLAKVRLNPEECADVLRRWVDHLCSPQVNQKSKALLVLLSLGCFFSV 1140
Query: 1141 AETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFA 1200
AETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFA
Sbjct: 1141 AETLHSMRYFDRAALFVEACLKYGAFEVTEDTEKLITAIYADYARSLKNLGFKQGAVLFA 1200
Query: 1201 SKAGAAGKDLLNELESPKEEPIEE 1224
SKAGAAGKDLLNELESPKEEPIEE
Sbjct: 1201 SKAGAAGKDLLNELESPKEEPIEE 1224
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 11/97 (11%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW G L+A G + I + L +HK + +KW R+ +
Sbjct: 242 SLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNY--------- 292
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQW 121
+ SA V+ I+WD G A+ + H+ P DV W
Sbjct: 293 -ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 328
Score = 39.3 bits (90), Expect = 0.023
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 15/114 (13%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKW- 69
+T G N N A+ W G++ C + + I S+ + + L+ H ++ +KW
Sbjct: 355 KTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 412
Query: 70 ----ARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDV 119
A N + NI LASA + + +WD+ GV + +H +P+ V
Sbjct: 413 PTGPATSNPNSNI------MLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSV 460
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 10/115 (8%)
Query: 713 ITCIAWK--GDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W G L G DG W G ++ + H+ + +++ KGN L A
Sbjct: 240 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNR-KGNYILSAGV 298
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW + S D CI V +
Sbjct: 299 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQNNTTFASCSTDMCIHVCRL 348
Score = 31.6 bits (70), Expect = 4.8
Identities = 30/137 (21%), Positives = 56/137 (40%), Gaps = 21/137 (15%)
Query: 22 HNKAAVDWGWQGLIAYGCHSLVVVIDSITA---QTLQVLEKHKADVVKVKWARENYHHNI 78
H+ A+D WQ + S + I + ++ + H +V +KW
Sbjct: 319 HSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW--------- 369
Query: 79 GSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPP 138
P + LAS + + +W + V ++Q H K I ++W A+ +P
Sbjct: 370 -DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS------NPN 422
Query: 139 NYIVLWNA--DTGTKLW 153
+ I+L +A D+ +LW
Sbjct: 423 SNIMLASASFDSTVRLW 439
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 11/97 (11%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW G L+A G + I + L +HK + +KW R+ +
Sbjct: 242 SLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNY--------- 292
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQW 121
+ SA V+ I+WD G A+ + H+ P DV W
Sbjct: 293 -ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 328
Score = 39.3 bits (90), Expect = 0.023
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 15/114 (13%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKW- 69
+T G N N A+ W G++ C + + I S+ + + L+ H ++ +KW
Sbjct: 355 KTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 412
Query: 70 ----ARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDV 119
A N + NI LASA + + +WD+ GV + +H +P+ V
Sbjct: 413 PTGPATSNPNSNI------MLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSV 460
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 10/115 (8%)
Query: 713 ITCIAWK--GDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W G L G DG W G ++ + H+ + +++ KGN L A
Sbjct: 240 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNR-KGNYILSAGV 298
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW + S D CI V +
Sbjct: 299 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQNNTTFASCSTDMCIHVCRL 348
Score = 31.6 bits (70), Expect = 4.8
Identities = 30/137 (21%), Positives = 56/137 (40%), Gaps = 21/137 (15%)
Query: 22 HNKAAVDWGWQGLIAYGCHSLVVVIDSITA---QTLQVLEKHKADVVKVKWARENYHHNI 78
H+ A+D WQ + S + I + ++ + H +V +KW
Sbjct: 319 HSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW--------- 369
Query: 79 GSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPP 138
P + LAS + + +W + V ++Q H K I ++W A+ +P
Sbjct: 370 -DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS------NPN 422
Query: 139 NYIVLWNA--DTGTKLW 153
+ I+L +A D+ +LW
Sbjct: 423 SNIMLASASFDSTVRLW 439
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 11/97 (11%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW G L+A G + I + L +HK + +KW R+ +
Sbjct: 293 SLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNY--------- 343
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQW 121
+ SA V+ I+WD G A+ + H+ P DV W
Sbjct: 344 -ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 379
Score = 39.3 bits (90), Expect = 0.023
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 15/114 (13%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKW- 69
+T G N N A+ W G++ C + + I S+ + + L+ H ++ +KW
Sbjct: 406 KTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 463
Query: 70 ----ARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDV 119
A N + NI LASA + + +WD+ GV + +H +P+ V
Sbjct: 464 PTGPATSNPNSNI------MLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSV 511
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 10/115 (8%)
Query: 713 ITCIAWK--GDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W G L G DG W G ++ + H+ + +++ KGN L A
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNR-KGNYILSAGV 349
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW + S D CI V +
Sbjct: 350 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQNNTTFASCSTDMCIHVCRL 399
Score = 31.6 bits (70), Expect = 4.8
Identities = 30/137 (21%), Positives = 56/137 (40%), Gaps = 21/137 (15%)
Query: 22 HNKAAVDWGWQGLIAYGCHSLVVVIDSITA---QTLQVLEKHKADVVKVKWARENYHHNI 78
H+ A+D WQ + S + I + ++ + H +V +KW
Sbjct: 370 HSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW--------- 420
Query: 79 GSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPP 138
P + LAS + + +W + V ++Q H K I ++W A+ +P
Sbjct: 421 -DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS------NPN 473
Query: 139 NYIVLWNA--DTGTKLW 153
+ I+L +A D+ +LW
Sbjct: 474 SNIMLASASFDSTVRLW 490
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 11/97 (11%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW G L+A G + I + L +HK + +KW R+ +
Sbjct: 293 SLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNY--------- 343
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQW 121
+ SA V+ I+WD G A+ + H+ P DV W
Sbjct: 344 -ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 379
Score = 39.3 bits (90), Expect = 0.023
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 15/114 (13%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKW- 69
+T G N N A+ W G++ C + + I S+ + + L+ H ++ +KW
Sbjct: 406 KTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 463
Query: 70 ----ARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDV 119
A N + NI LASA + + +WD+ GV + +H +P+ V
Sbjct: 464 PTGPATSNPNSNI------MLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSV 511
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 45/115 (39%), Gaps = 10/115 (8%)
Query: 713 ITCIAWK--GDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W G L G DG W G ++ + H+ + +++ KGN L A
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNR-KGNYILSAGV 349
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW + S D CI V +
Sbjct: 350 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQNNTTFASCSTDMCIHVCRL 399
Score = 31.6 bits (70), Expect = 4.8
Identities = 30/137 (21%), Positives = 56/137 (40%), Gaps = 21/137 (15%)
Query: 22 HNKAAVDWGWQGLIAYGCHSLVVVIDSITA---QTLQVLEKHKADVVKVKWARENYHHNI 78
H+ A+D WQ + S + I + ++ + H +V +KW
Sbjct: 370 HSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW--------- 420
Query: 79 GSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPP 138
P + LAS + + +W + V ++Q H K I ++W A+ +P
Sbjct: 421 -DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS------NPN 473
Query: 139 NYIVLWNA--DTGTKLW 153
+ I+L +A D+ +LW
Sbjct: 474 SNIMLASASFDSTVRLW 490
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 41.2 bits (95), Expect = 0.006
Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 28/222 (12%)
Query: 589 DKPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTE 648
DK + ++D + +L + + +T++ + PS +L A+ +A R V +
Sbjct: 243 DKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFS-----ASPDATIRIWSVPNAS 297
Query: 649 LSIV----ESSVISLLQEAESKSELSQNISAREHFVFTDID-GQVYHLTVEGNSVKDSAR 703
V ES+V L A LS S +++ F+DI G+V +
Sbjct: 298 CVQVVRAHESAVTGLSLHATGDYLLSS--SDDQYWAFSDIQTGRVL------------TK 343
Query: 704 IPPDGSMGSITCIAWKGDTLVLGD--MDGNLNFWDLKGRVS-RGIPTHRSWVRKIRFAPG 760
+ + S S+TC + D L+ G MD + WDLK R + P H + I F+
Sbjct: 344 VTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE- 402
Query: 761 KGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVD 802
G A + ++WD ++++ +L+ N + L D
Sbjct: 403 NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD 444
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 41.2 bits (95), Expect = 0.006
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 12/113 (10%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW G L+A G + I + L +HK + +KW ++ +
Sbjct: 240 SLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNY--------- 290
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQD-ASRDLLLAIH 136
+ SA V+ I+WD G A+ + H+ P DV W N AS + IH
Sbjct: 291 -VLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIH 342
Score = 40.0 bits (92), Expect = 0.014
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 19/145 (13%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKW- 69
+T G N N A+ W G++ C + + I S+ + L+ H ++ +KW
Sbjct: 353 KTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 70 ----ARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQ 125
A N + +I LASA + + +WDV GV + +H +P+ V +
Sbjct: 411 PTGPATSNPNSSI------MLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF---- 460
Query: 126 DASRDLLLAIHPPNYIVLWNADTGT 150
L + Y+ +WN +G+
Sbjct: 461 SPDGKYLASGSFDKYVHIWNTQSGS 485
Score = 38.1 bits (87), Expect = 0.052
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 713 ITCIAWKGD--TLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W D L +G DG W G ++ + H+ + +++ KGN L A
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNK-KGNYVLSAGV 296
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW + S D CI V +
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQNNMTFASCSTDMCIHVCRL 346
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 41.2 bits (95), Expect = 0.006
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 12/113 (10%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW G L+A G + I + L +HK + +KW ++ +
Sbjct: 240 SLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNY--------- 290
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQD-ASRDLLLAIH 136
+ SA V+ I+WD G A+ + H+ P DV W N AS + IH
Sbjct: 291 -VLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIH 342
Score = 40.0 bits (92), Expect = 0.014
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 19/145 (13%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKW- 69
+T G N N A+ W G++ C + + I S+ + L+ H ++ +KW
Sbjct: 353 KTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 70 ----ARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQ 125
A N + +I LASA + + +WDV GV + +H +P+ V +
Sbjct: 411 PTGPATSNPNSSI------MLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF---- 460
Query: 126 DASRDLLLAIHPPNYIVLWNADTGT 150
L + Y+ +WN +G+
Sbjct: 461 SPDGKYLASGSFDKYVHIWNTQSGS 485
Score = 38.1 bits (87), Expect = 0.052
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 713 ITCIAWKGD--TLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W D L +G DG W G ++ + H+ + +++ KGN L A
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNK-KGNYVLSAGV 296
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW + S D CI V +
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQNNMTFASCSTDMCIHVCRL 346
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 41.2 bits (95), Expect = 0.006
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 12/113 (10%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW G L+A G + I + L +HK + +KW ++ +
Sbjct: 240 SLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNY--------- 290
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQD-ASRDLLLAIH 136
+ SA V+ I+WD G A+ + H+ P DV W N AS + IH
Sbjct: 291 -VLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIH 342
Score = 40.0 bits (92), Expect = 0.014
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 19/145 (13%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKW- 69
+T G N N A+ W G++ C + + I S+ + L+ H ++ +KW
Sbjct: 353 KTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 70 ----ARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQ 125
A N + +I LASA + + +WDV GV + +H +P+ V +
Sbjct: 411 PTGPATSNPNSSI------MLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF---- 460
Query: 126 DASRDLLLAIHPPNYIVLWNADTGT 150
L + Y+ +WN +G+
Sbjct: 461 SPDGKYLASGSFDKYVHIWNTQSGS 485
Score = 38.1 bits (87), Expect = 0.052
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 713 ITCIAWKGD--TLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W D L +G DG W G ++ + H+ + +++ KGN L A
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNK-KGNYVLSAGV 296
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW + S D CI V +
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQNNMTFASCSTDMCIHVCRL 346
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 40.8 bits (94), Expect = 0.008
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 12/113 (10%)
Query: 26 AVDWGWQG-LIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCL 84
++DW +G L+A G + I + L +HK + +KW ++
Sbjct: 230 SLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNF--------- 280
Query: 85 RLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQD-ASRDLLLAIH 136
+ SA V+ I+WD G A+ + H+ P DV W N AS + IH
Sbjct: 281 -ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIH 332
Score = 38.1 bits (87), Expect = 0.052
Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 10/115 (8%)
Query: 713 ITCIAW--KGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMY 770
+T + W +G L G DG W G ++ + H+ + +++ KGN L A
Sbjct: 228 VTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNK-KGNFILSAGV 286
Query: 771 NDGAEVWD--TKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEM 823
+ +WD T E + S LDVDW +++ S D CI V ++
Sbjct: 287 DKTTIIWDAHTGEAKQQFPFHSAP-----ALDVDWQSNNTFASCSTDMCIHVCKL 336
Score = 35.0 bits (79), Expect = 0.44
Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 13/141 (9%)
Query: 13 RTLTGALNAHNKAAVDWGWQGLIAYGCHS-LVVVIDSITAQT-LQVLEKHKADVVKVKWA 70
+T G N N A+ W G + C + + I S+ + L+ H ++ +KW+
Sbjct: 343 KTFQGHTNEVN--AIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400
Query: 71 RENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWL--WNQDAS 128
N + L LASA + + +WDV G+ + +H +P+ V + AS
Sbjct: 401 PTGPGTNNPNAN-LMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 459
Query: 129 RDLLLAIHPPNYIVLWNADTG 149
+H +WN TG
Sbjct: 460 GSFDKCVH------IWNTQTG 474
Score = 32.0 bits (71), Expect = 3.7
Identities = 26/135 (19%), Positives = 56/135 (41%), Gaps = 13/135 (9%)
Query: 487 LLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNE 546
+L+ G + +++ +G ++ HS ++W S +F S +T
Sbjct: 281 ILSAGVDK-TTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMC--------- 330
Query: 547 LQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREM 606
+ + L R I N+ +AI+ +L LA D L++W ++ + ++
Sbjct: 331 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNL---LASCSDDMTLKIWSMKQDNCVHDL 387
Query: 607 SKNFPTITALEWSPS 621
+ I ++WSP+
Sbjct: 388 QAHNKEIYTIKWSPT 402
>gi|217330644 WD repeat domain 12 protein [Homo sapiens]
Length = 423
Score = 39.7 bits (91), Expect = 0.018
Identities = 51/233 (21%), Positives = 89/233 (38%), Gaps = 42/233 (18%)
Query: 589 DKPLELWDVRTCTLLREMSKNFPTITALEWSPSHNLKSLRKKQLATREAMARQTVVSDTE 648
DK L++W PT E S N RKKQ + + R +V+ +
Sbjct: 210 DKMLKIWST------------VPTDEEDEMEESTNRP--RKKQKTEQLGLTRTPIVTLSG 255
Query: 649 LSIVESSVISLLQEAESKSELSQNISAREHFVFTDIDGQVYHLTVEGNSVKDSARIPPDG 708
SSV L +AE S + + R D++ T+ GN V
Sbjct: 256 HMEAVSSV--LWSDAEEICSASWDHTIR----VWDVESGSLKSTLTGNKV---------- 299
Query: 709 SMGSITCIAWKG--DTLVLGDMDGNLNFWDLKGR----VSRGIPTHRSWVRKIRFAPGKG 762
CI++ L G D ++ WD + + VS + +H WV ++++P
Sbjct: 300 ----FNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHE 355
Query: 763 NQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDD 815
Q + ++ ++WDT+ + + L ++L VDW + ++ D
Sbjct: 356 QQLISGSLDNIVKLWDTRSCK--APLYDLAAHEDKVLSVDWTDTGLLLSGGAD 406
>gi|8922735 elongator protein 2 [Homo sapiens]
Length = 826
Score = 39.7 bits (91), Expect = 0.018
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 14/136 (10%)
Query: 24 KAAVDW--GWQGLIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSP 81
+ ++W G +GL+A+G VV+ D + + L H A V ++W + GSP
Sbjct: 19 RGVLNWSSGPRGLLAFGTSCSVVLYDPLKRVVVTNLNGHTARVNCIQWICK----QDGSP 74
Query: 82 YCLRLASADVNGKIIVWDVAAG--VAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPPN 139
L S + ++I W++ + +Q H P+ V ++ + S L +
Sbjct: 75 -STELVSGGSDNQVIHWEIEDNQLLKAVHLQGHEGPVYAVHAVYQRRTSDPALCTL---- 129
Query: 140 YIVLWNADTGTKLWKK 155
IV AD+ +LW K
Sbjct: 130 -IVSAAADSAVRLWSK 144
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 39.7 bits (91), Expect = 0.018
Identities = 25/111 (22%), Positives = 49/111 (44%), Gaps = 8/111 (7%)
Query: 86 LASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPPNYIVLWN 145
LASA + +I+WD++ G + H +Q +Q+ L++ + L++
Sbjct: 272 LASASADNTVILWDMSLGKPAASLAVHTDKVQTLQF---HPFEAQTLISGSYDKSVALYD 328
Query: 146 A---DTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSEGIVFISDFSPSKP 193
D ++W+ ++ I +++ F P H T +G V+ D KP
Sbjct: 329 CRSPDESHRMWR--FSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKP 377
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 39.7 bits (91), Expect = 0.018
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 10/108 (9%)
Query: 713 ITCIAWKGDTLVLGDMDGNLNFWDL-KGRVSRGIP-THRSWVRKIRFAPGKGNQKLIAMY 770
I C+A +GD L G D + WDL + + + IP H+ WV + F PG+ L++
Sbjct: 1494 IECLAIQGDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGR--PMLLSAC 1551
Query: 771 NDGA-EVWDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGC 817
G +VW+ + ++ + I CT+ K I + C
Sbjct: 1552 RAGVIKVWNVDNFTPIGEIKGHDSPINAI-----CTNAKHIFTASSDC 1594
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 38.1 bits (87), Expect = 0.052
Identities = 33/137 (24%), Positives = 52/137 (37%), Gaps = 30/137 (21%)
Query: 67 VKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQD 126
+ W+ +YH N+ LAS+D G +I+WD G QEH K W+ D
Sbjct: 476 ISWS--SYHKNL-------LASSDYEGTVILWDGFTGQRSKVYQEHEKR------CWSVD 520
Query: 127 ASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSF---------SFDPFDPSHLTLL 177
+ + P + + D KLW + +++ S F P HL
Sbjct: 521 FN------LMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFG 574
Query: 178 TSEGIVFISDFSPSKPP 194
++ V D +K P
Sbjct: 575 CADHCVHYYDLRNTKQP 591
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 38.1 bits (87), Expect = 0.052
Identities = 33/137 (24%), Positives = 52/137 (37%), Gaps = 30/137 (21%)
Query: 67 VKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQD 126
+ W+ +YH N+ LAS+D G +I+WD G QEH K W+ D
Sbjct: 452 ISWS--SYHKNL-------LASSDYEGTVILWDGFTGQRSKVYQEHEKR------CWSVD 496
Query: 127 ASRDLLLAIHPPNYIVLWNADTGTKLWKKSYADNILSF---------SFDPFDPSHLTLL 177
+ + P + + D KLW + +++ S F P HL
Sbjct: 497 FN------LMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFG 550
Query: 178 TSEGIVFISDFSPSKPP 194
++ V D +K P
Sbjct: 551 CADHCVHYYDLRNTKQP 567
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 38.1 bits (87), Expect = 0.052
Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 13/131 (9%)
Query: 22 HNKAAVDWGWQGL-IAYGCHSLVVVI--DSITAQTLQVLEKHKADVVKVKWARENYHHNI 78
H ++ W G +A GC + +++ S Q + L H + + W E H N
Sbjct: 157 HWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSW--EPLHAN- 213
Query: 79 GSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPP 138
P C +AS+ +G + +WD AG + + H + + ++W LL +
Sbjct: 214 --PECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRW-----GGDGLLYSASQD 266
Query: 139 NYIVLWNADTG 149
I +W A G
Sbjct: 267 RTIKVWRAHDG 277
>gi|4502477 beta-transducin repeat containing protein isoform 2
[Homo sapiens]
Length = 569
Score = 37.0 bits (84), Expect = 0.12
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 707 DGSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQK 765
+G I C+ ++ +V G D + WD++ G R + H VR IRF N++
Sbjct: 427 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF----DNKR 482
Query: 766 LIAMYNDG-AEVWD 778
+++ DG +VWD
Sbjct: 483 IVSGAYDGKIKVWD 496
Score = 33.1 bits (74), Expect = 1.7
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 13/122 (10%)
Query: 708 GSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQKL 766
G GS+ C+ + ++ G D + WD+ G + + H V +RF N +
Sbjct: 305 GHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRF----NNGMM 360
Query: 767 IAMYND-GAEVWDTKEVQMVSSLR--SGRNVTFRILDVDWCTSDK-VILASDDGCIRVLE 822
+ D VWD ++ R G ++D D DK ++ AS D I+V
Sbjct: 361 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWN 416
Query: 823 MS 824
S
Sbjct: 417 TS 418
>gi|16117783 beta-transducin repeat containing protein isoform 1
[Homo sapiens]
Length = 605
Score = 37.0 bits (84), Expect = 0.12
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 707 DGSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQK 765
+G I C+ ++ +V G D + WD++ G R + H VR IRF N++
Sbjct: 463 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF----DNKR 518
Query: 766 LIAMYNDG-AEVWD 778
+++ DG +VWD
Sbjct: 519 IVSGAYDGKIKVWD 532
Score = 33.1 bits (74), Expect = 1.7
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 13/122 (10%)
Query: 708 GSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQKL 766
G GS+ C+ + ++ G D + WD+ G + + H V +RF N +
Sbjct: 341 GHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRF----NNGMM 396
Query: 767 IAMYND-GAEVWDTKEVQMVSSLR--SGRNVTFRILDVDWCTSDK-VILASDDGCIRVLE 822
+ D VWD ++ R G ++D D DK ++ AS D I+V
Sbjct: 397 VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWN 452
Query: 823 MS 824
S
Sbjct: 453 TS 454
>gi|48928050 F-box and WD repeat domain containing 11 isoform C
[Homo sapiens]
Length = 542
Score = 37.0 bits (84), Expect = 0.12
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 707 DGSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQK 765
+G I C+ ++ +V G D + WD++ G R + H VR IRF N++
Sbjct: 400 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF----DNKR 455
Query: 766 LIAMYNDG-AEVWD 778
+++ DG +VWD
Sbjct: 456 IVSGAYDGKIKVWD 469
Score = 36.6 bits (83), Expect = 0.15
Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 708 GSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQKL 766
G GS+ C+ + +V G D + WD+ G V + H V +RF+ G +
Sbjct: 278 GHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG---LMV 334
Query: 767 IAMYNDGAEVWDTKEVQMVSSLR--SGRNVTFRILDVDWCTSDK-VILASDDGCIRVLEM 823
+ VWD ++ R G ++D D DK ++ AS D I+V
Sbjct: 335 TCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWST 390
Query: 824 S 824
S
Sbjct: 391 S 391
>gi|48928048 F-box and WD repeat domain containing 11 isoform A
[Homo sapiens]
Length = 508
Score = 37.0 bits (84), Expect = 0.12
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 707 DGSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQK 765
+G I C+ ++ +V G D + WD++ G R + H VR IRF N++
Sbjct: 366 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF----DNKR 421
Query: 766 LIAMYNDG-AEVWD 778
+++ DG +VWD
Sbjct: 422 IVSGAYDGKIKVWD 435
Score = 36.6 bits (83), Expect = 0.15
Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 708 GSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQKL 766
G GS+ C+ + +V G D + WD+ G V + H V +RF+ G +
Sbjct: 244 GHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG---LMV 300
Query: 767 IAMYNDGAEVWDTKEVQMVSSLR--SGRNVTFRILDVDWCTSDK-VILASDDGCIRVLEM 823
+ VWD ++ R G ++D D DK ++ AS D I+V
Sbjct: 301 TCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWST 356
Query: 824 S 824
S
Sbjct: 357 S 357
>gi|48928046 F-box and WD repeat domain containing 11 isoform B
[Homo sapiens]
Length = 529
Score = 37.0 bits (84), Expect = 0.12
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 707 DGSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQK 765
+G I C+ ++ +V G D + WD++ G R + H VR IRF N++
Sbjct: 387 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF----DNKR 442
Query: 766 LIAMYNDG-AEVWD 778
+++ DG +VWD
Sbjct: 443 IVSGAYDGKIKVWD 456
Score = 36.6 bits (83), Expect = 0.15
Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 708 GSMGSITCIAWKGDTLVLGDMDGNLNFWDLK-GRVSRGIPTHRSWVRKIRFAPGKGNQKL 766
G GS+ C+ + +V G D + WD+ G V + H V +RF+ G +
Sbjct: 265 GHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNG---LMV 321
Query: 767 IAMYNDGAEVWDTKEVQMVSSLR--SGRNVTFRILDVDWCTSDK-VILASDDGCIRVLEM 823
+ VWD ++ R G ++D D DK ++ AS D I+V
Sbjct: 322 TCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWST 377
Query: 824 S 824
S
Sbjct: 378 S 378
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 36.6 bits (83), Expect = 0.15
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 720 GDTLVLGDMDGNLNFWDLKGR-VSRGIPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEVW 777
G + G D WDL+ R IP H++ V ++F P GN L Y++ A++W
Sbjct: 419 GYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 36.6 bits (83), Expect = 0.15
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 541 GLVRNELQLVDLPTGRSIA-FRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRT 599
G ++L G S+ F G RG + + S +YLA D+ L+LWD+ +
Sbjct: 444 GSTDKTVRLWSAQQGNSVRLFTGHRG----PVLSLAFSPNGKYLASAGEDQRLKLWDLAS 499
Query: 600 CTLLREMSKNFPTITALEWSPSHNL 624
TL +E+ + IT+L +SP L
Sbjct: 500 GTLYKELRGHTDNITSLTFSPDSGL 524
>gi|55769546 PAK1 interacting protein 1 [Homo sapiens]
Length = 392
Score = 36.6 bits (83), Expect = 0.15
Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 712 SITCIAWKGDTLVLGDMDGNLNFWDLKGRVSRGIPTHRSWVRKIRFAPGKGNQKLIAMYN 771
S++ +A +V G D ++ +D+K ++ G H S I GN+ LI+
Sbjct: 44 SLSAVAVNSRFVVTGSKDETIHIYDMKKKIEHGALVHHSGT--ITCLKFYGNRHLISGAE 101
Query: 772 DGAE-VWDTKEVQMVSSLRSGR-NVTF 796
DG +WD K+ + + S+++ + VTF
Sbjct: 102 DGLICIWDAKKWECLKSIKAHKGQVTF 128
>gi|209969680 Fzr1 protein isoform 1 [Homo sapiens]
Length = 496
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 22/160 (13%)
Query: 26 AVDWGWQG-LIAYGCHS-LVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYC 83
+V W +G L+A G H V + D+ + L +LE H A V + W E
Sbjct: 234 SVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE----------- 282
Query: 84 LRLASADVNGKIIVWDVAAGVAQCE--IQEHAKPIQDVQWLWNQDASRDLLLAIHPPNYI 141
+L+S + I+ D+ Q E +Q H + + ++W LL + N +
Sbjct: 283 -QLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKW----STDHQLLASGGNDNKL 337
Query: 142 VLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSEG 181
++WN + + + + Y +++ + + P LL S G
Sbjct: 338 LVWNHSSLSPV--QQYTEHLAAVKAIAWSPHQHGLLASGG 375
Score = 34.3 bits (77), Expect = 0.75
Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 11/134 (8%)
Query: 487 LLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNE 546
L+AVGT G V ++ +G L H+ V + W + +S + +++ +
Sbjct: 243 LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA-----EQLSSGSRDRMILQRD 297
Query: 547 LQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREM 606
++ L + R + +G R + +K S Q LA D L +W+ + + +++
Sbjct: 298 IRTPPLQSERRL--QGHR----QEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
Query: 607 SKNFPTITALEWSP 620
+++ + A+ WSP
Sbjct: 352 TEHLAAVKAIAWSP 365
>gi|209969678 Fzr1 protein isoform 3 [Homo sapiens]
Length = 404
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 22/160 (13%)
Query: 26 AVDWGWQG-LIAYGCHS-LVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYC 83
+V W +G L+A G H V + D+ + L +LE H A V + W E
Sbjct: 145 SVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE----------- 193
Query: 84 LRLASADVNGKIIVWDVAAGVAQCE--IQEHAKPIQDVQWLWNQDASRDLLLAIHPPNYI 141
+L+S + I+ D+ Q E +Q H + + ++W LL + N +
Sbjct: 194 -QLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKW----STDHQLLASGGNDNKL 248
Query: 142 VLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSEG 181
++WN + + + + Y +++ + + P LL S G
Sbjct: 249 LVWNHSSLSPV--QQYTEHLAAVKAIAWSPHQHGLLASGG 286
Score = 34.3 bits (77), Expect = 0.75
Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 11/134 (8%)
Query: 487 LLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNE 546
L+AVGT G V ++ +G L H+ V + W + +S + +++ +
Sbjct: 154 LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA-----EQLSSGSRDRMILQRD 208
Query: 547 LQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREM 606
++ L + R + +G R + +K S Q LA D L +W+ + + +++
Sbjct: 209 IRTPPLQSERRL--QGHR----QEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 262
Query: 607 SKNFPTITALEWSP 620
+++ + A+ WSP
Sbjct: 263 TEHLAAVKAIAWSP 276
>gi|33620742 Fzr1 protein isoform 2 [Homo sapiens]
Length = 493
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 22/160 (13%)
Query: 26 AVDWGWQG-LIAYGCHS-LVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYC 83
+V W +G L+A G H V + D+ + L +LE H A V + W E
Sbjct: 234 SVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE----------- 282
Query: 84 LRLASADVNGKIIVWDVAAGVAQCE--IQEHAKPIQDVQWLWNQDASRDLLLAIHPPNYI 141
+L+S + I+ D+ Q E +Q H + + ++W LL + N +
Sbjct: 283 -QLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKW----STDHQLLASGGNDNKL 337
Query: 142 VLWNADTGTKLWKKSYADNILSFSFDPFDPSHLTLLTSEG 181
++WN + + + + Y +++ + + P LL S G
Sbjct: 338 LVWNHSSLSPV--QQYTEHLAAVKAIAWSPHQHGLLASGG 375
Score = 34.3 bits (77), Expect = 0.75
Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 11/134 (8%)
Query: 487 LLAVGTSNGSVLVYHLTSGLLHKELSIHSCEVKGIEWTSLTSFLSFATSTPNNMGLVRNE 546
L+AVGT G V ++ +G L H+ V + W + +S + +++ +
Sbjct: 243 LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA-----EQLSSGSRDRMILQRD 297
Query: 547 LQLVDLPTGRSIAFRGERGNDESAIEMIKVSHLKQYLAVVFRDKPLELWDVRTCTLLREM 606
++ L + R + +G R + +K S Q LA D L +W+ + + +++
Sbjct: 298 IRTPPLQSERRL--QGHR----QEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
Query: 607 SKNFPTITALEWSP 620
+++ + A+ WSP
Sbjct: 352 TEHLAAVKAIAWSP 365
>gi|14149696 SEC31 homolog B [Homo sapiens]
Length = 1179
Score = 35.8 bits (81), Expect = 0.26
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 15/121 (12%)
Query: 63 DVVKVKWARENYHHNIGSPYCLRLASADVNGKIIVWDVAAGVAQCEIQEHAKPIQDVQWL 122
D+ + W R+ H L+SA +GK +VWD+ ++ +H+ +
Sbjct: 170 DIKALSWNRQAQHI---------LSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLA 220
Query: 123 WNQDASRDLLLAIHPPN--YIVLWNADTGTKLWK--KSYADNILSFSFDPFDPSHLTLLT 178
W+ D + L+L I LW+ + K +S++ ILS S+ D LLT
Sbjct: 221 WHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAE--LLLT 278
Query: 179 S 179
S
Sbjct: 279 S 279
>gi|94400919 WD repeat domain 90 [Homo sapiens]
Length = 1748
Score = 35.8 bits (81), Expect = 0.26
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 7/152 (4%)
Query: 33 GLIAYGCHSLVVVIDSITAQTLQVLEKHKADVVKVKWARENYHHNIGSPYCLRLASADVN 92
G AY C LVVV D + + Q H A++ + + H +S +
Sbjct: 1131 GFFAYTCGRLVVVED-LHSGAQQHWSGHSAEISTLALS----HSAQVLASASGRSSTTAH 1185
Query: 93 GKIIVWDVAAGVAQCEIQEHAKPIQDVQWLWNQDASRDLLLAIHPPNYIVLWNADTGTKL 152
+I VWDV+ G+ Q I H+ + + ++ D + L H + LW T +
Sbjct: 1186 CQIRVWDVSGGLCQHLIFPHSTTV--LALAFSPDDRLLVTLGDHDGRTLALWGTATYDLV 1243
Query: 153 WKKSYADNILSFSFDPFDPSHLTLLTSEGIVF 184
+ + +F+P+D LT + + F
Sbjct: 1244 SSTRLPEPVHGVAFNPWDAGELTCVGQGTVTF 1275
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,643,926
Number of Sequences: 37866
Number of extensions: 1995602
Number of successful extensions: 5425
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 5168
Number of HSP's gapped (non-prelim): 313
length of query: 1224
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1110
effective length of database: 13,930,794
effective search space: 15463181340
effective search space used: 15463181340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.