Guide to the Human Genome
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Search of human proteins with 48255937

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48255937 CD44 antigen isoform 2 precursor [Homo sapiens]
         (699 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48255937 CD44 antigen isoform 2 precursor [Homo sapiens]          1449   0.0  
gi|48255935 CD44 antigen isoform 1 precursor [Homo sapiens]          1427   0.0  
gi|48255939 CD44 antigen isoform 3 precursor [Homo sapiens]           543   e-154
gi|48255941 CD44 antigen isoform 4 precursor [Homo sapiens]           468   e-132
gi|48255943 CD44 antigen isoform 5 precursor [Homo sapiens]           165   2e-40
gi|40549451 lymphatic vessel endothelial hyaluronan receptor 1 [...    77   7e-14
gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu...    64   6e-10
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    62   1e-09
gi|167736355 mucin 4 isoform a [Homo sapiens]                          59   2e-08
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             57   4e-08
gi|161016767 mucin 21 [Homo sapiens]                                   57   8e-08
gi|61743978 stabilin 1 precursor [Homo sapiens]                        52   1e-06
gi|60097902 filaggrin [Homo sapiens]                                   52   2e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        51   3e-06
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             50   7e-06
gi|161019170 mucin 5AC [Homo sapiens]                                  49   1e-05
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    49   1e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    48   3e-05
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|62122917 filaggrin family member 2 [Homo sapiens]                   47   6e-05
gi|38372931 brevican isoform 2 [Homo sapiens]                          47   8e-05
gi|38372935 brevican isoform 1 [Homo sapiens]                          47   8e-05

>gi|48255937 CD44 antigen isoform 2 precursor [Homo sapiens]
          Length = 699

 Score = 1449 bits (3752), Expect = 0.0
 Identities = 699/699 (100%), Positives = 699/699 (100%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE 240
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE 240

Query: 241 DERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTR 300
           DERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTR
Sbjct: 241 DERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTR 300

Query: 301 MTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQW 360
           MTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQW
Sbjct: 301 MTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQW 360

Query: 361 FGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGR 420
           FGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGR
Sbjct: 361 FGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGR 420

Query: 421 GHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED 480
           GHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED
Sbjct: 421 GHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED 480

Query: 481 KDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS 540
           KDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS
Sbjct: 481 KDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS 540

Query: 541 FGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIR 600
           FGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIR
Sbjct: 541 FGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIR 600

Query: 601 TPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEA 660
           TPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEA
Sbjct: 601 TPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEA 660

Query: 661 SKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV 699
           SKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV
Sbjct: 661 SKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV 699


>gi|48255935 CD44 antigen isoform 1 precursor [Homo sapiens]
          Length = 742

 Score = 1427 bits (3695), Expect = 0.0
 Identities = 698/742 (94%), Positives = 699/742 (94%), Gaps = 43/742 (5%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATS----------------- 223
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT+                 
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE 240

Query: 224 --------------------------TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 257
                                     TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD
Sbjct: 241 TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 300

Query: 258 EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN 317
           EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN
Sbjct: 301 EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN 360

Query: 318 PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS 377
           PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS
Sbjct: 361 PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS 420

Query: 378 HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT 437
           HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT
Sbjct: 421 HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT 480

Query: 438 LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV 497
           LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV
Sbjct: 481 LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV 540

Query: 498 TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR 557
           TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR
Sbjct: 541 TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR 600

Query: 558 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 617
           SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL
Sbjct: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660

Query: 618 ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET 677
           ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET
Sbjct: 661 ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET 720

Query: 678 PDQFMTADETRNLQNVDMKIGV 699
           PDQFMTADETRNLQNVDMKIGV
Sbjct: 721 PDQFMTADETRNLQNVDMKIGV 742


>gi|48255939 CD44 antigen isoform 3 precursor [Homo sapiens]
          Length = 493

 Score =  543 bits (1400), Expect = e-154
 Identities = 283/326 (86%), Positives = 289/326 (88%), Gaps = 18/326 (5%)

Query: 375 EDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSW-TDFFNPISHPMGRGHQAGRRMDMDSS 433
           E S ++ G    +  T HP+        EDS W TD  + I              +MDSS
Sbjct: 185 ERSSTSGGYIFYTFSTVHPIPD------EDSPWITDSTDRIP-----------ATNMDSS 227

Query: 434 HSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSN 493
           HSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSN
Sbjct: 228 HSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSN 287

Query: 494 RNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNS 553
           RNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNS
Sbjct: 288 RNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNS 347

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILAS 613
           NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILAS
Sbjct: 348 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILAS 407

Query: 614 LLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKE 673
           LLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKE
Sbjct: 408 LLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKE 467

Query: 674 SSETPDQFMTADETRNLQNVDMKIGV 699
           SSETPDQFMTADETRNLQNVDMKIGV
Sbjct: 468 SSETPDQFMTADETRNLQNVDMKIGV 493



 Score =  481 bits (1237), Expect = e-135
 Identities = 265/422 (62%), Positives = 290/422 (68%), Gaps = 50/422 (11%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT---STSSNTISAGWEPNE 237
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT   S+ S T+     PN 
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATNMDSSHSITLQPTANPNT 240

Query: 238 ENEDERDR--------------HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 283
              ++ DR                S S  G+++D+D  +++  T+    D T   +D   
Sbjct: 241 GLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRD--- 297

Query: 284 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 343
             P+HS                   TT  EG  +        H+ H +E  T    ++ +
Sbjct: 298 --PNHS----------------EGSTTLLEGYTS--------HYPHTKESRTFIPVTSAK 331

Query: 344 ATPSSTTEETATQKEQWFGNRWHEGYRQT--PKEDSHSTTGTAA-ASAHTSHPMQGRTTP 400
                 T  T         NR   G + T  P   SH+T G+ +   +H S      TT 
Sbjct: 332 TGSFGVTAVTVGDSNSNV-NRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 390

Query: 401 SP 402
            P
Sbjct: 391 GP 392


>gi|48255941 CD44 antigen isoform 4 precursor [Homo sapiens]
          Length = 361

 Score =  468 bits (1205), Expect = e-132
 Identities = 228/253 (90%), Positives = 231/253 (91%), Gaps = 1/253 (0%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE 240
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT    +T       +  + 
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT-RDQDTFHPSGGSHTTHG 239

Query: 241 DERDRHLSFSGSG 253
            E D H   S  G
Sbjct: 240 SESDGHSHGSQEG 252



 Score =  279 bits (714), Expect = 6e-75
 Identities = 138/138 (100%), Positives = 138/138 (100%)

Query: 562 DQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALIL 621
           DQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALIL
Sbjct: 224 DQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALIL 283

Query: 622 AVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQF 681
           AVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQF
Sbjct: 284 AVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQF 343

Query: 682 MTADETRNLQNVDMKIGV 699
           MTADETRNLQNVDMKIGV
Sbjct: 344 MTADETRNLQNVDMKIGV 361


>gi|48255943 CD44 antigen isoform 5 precursor [Homo sapiens]
          Length = 139

 Score =  165 bits (417), Expect = 2e-40
 Identities = 77/77 (100%), Positives = 77/77 (100%)

Query: 1  MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
          MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1  MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61 PTMAQMEKALSIGFETC 77
          PTMAQMEKALSIGFETC
Sbjct: 61 PTMAQMEKALSIGFETC 77


>gi|40549451 lymphatic vessel endothelial hyaluronan receptor 1
           [Homo sapiens]
          Length = 322

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 41/115 (35%), Positives = 59/115 (51%), Gaps = 2/115 (1%)

Query: 17  LSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFET 76
           L   ++ + ++CR  G+  V K     ++ TEA + C+    +L    Q+E AL   FET
Sbjct: 25  LRAEELSIQVSCRIMGITLVSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFET 84

Query: 77  CRYGFI-EGHVVIPRIHPNSICAANNTGVYILTSNTS-QYDTYCFNASAPPEEDC 129
           C YG++ +G VVI RI PN  C  N  GV I     S Q+  YC+N+S      C
Sbjct: 85  CSYGWVGDGFVVISRISPNPKCGKNGVGVLIWKVPVSRQFAAYCYNSSDTWTNSC 139


>gi|26051243 tumor necrosis factor, alpha-induced protein 6
           precursor [Homo sapiens]
          Length = 277

 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 9/120 (7%)

Query: 29  RFAGVFHVE-KNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFI-EGHV 86
           R AGV+H E ++G+Y ++  EA  +C+     L T  Q+E A  IGF  C  G++ +G V
Sbjct: 33  RAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGRV 92

Query: 87  VIPRIHPNSICAANNTGVY---ILTSNTSQYDTYCFNASAPPEEDCTSV-TDLPNAFDGP 142
             P + P   C    TG+    I  + + ++D YC+N   P  ++C  V TD    F  P
Sbjct: 93  GYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYN---PHAKECGGVFTDPKQIFKSP 149


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 96/519 (18%), Positives = 200/519 (38%), Gaps = 35/519 (6%)

Query: 93  PNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRD- 151
           P +    +NTG     SN+  YD+Y F+  +   +D  S +D  N  D   + +  N   
Sbjct: 432 PGNKVGHSNTGS---DSNSDGYDSYDFDDKSMQGDDPNS-SDESNGNDDANSESDNNSSS 487

Query: 152 -GTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTF-----------S 199
            G       E + N          DDD  S S +  S ++G                  S
Sbjct: 488 RGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547

Query: 200 TVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDED 259
                   DS   +DS+D   + S+ SN+ S     + ++ D  D   S S +  D  + 
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607

Query: 260 FISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPE 319
             SS  S +  + D +K +   ++ + S S+        ++    D N + + + + + +
Sbjct: 608 SDSSDSSDSSDSSD-SKSDSSKSESDSSDSD--------SKSDSSDSNSSDSSDNSDSSD 658

Query: 320 AHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHS 379
           +       +  +  ++  S+S+  ++ SS + +++            E    +   DS S
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS------SESSDSSDSSDSDS 712

Query: 380 TTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQ 439
           +  + ++++++S      ++ S + S+ +D  +                   S  S +  
Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772

Query: 440 PTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLE--EDKDHPTTSTLTSSNRNDV 497
            + + ++    D + +   S ++  SNS   S S +  +  +  D  ++++  SSN +D 
Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832

Query: 498 TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR 557
           +      + S+ S +  +G  S   +  +S      + +   S    +    DSN + N 
Sbjct: 833 SDSSNSSDSSDSSDS-SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 558 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           S S D      S  S +++ S+S   S+ S    ++ +S
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 76/435 (17%), Positives = 168/435 (38%), Gaps = 15/435 (3%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            ++  D   SN +D D S+ S S  SS S                 DS   ++S+D   ++
Sbjct: 713  SDSSDSSNSNSSDSDSSNSSDSSDSSNSSD-------------SSDSSDSSNSSDSSDSS 759

Query: 223  STSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWT 282
             +S+++ S+    + ++ D  +   S   S   D  D  +S+ S+       +  + D  
Sbjct: 760  DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819

Query: 283  QWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTI 342
              N S S+       ++  +D   + + + +G+ +  ++     +     + +  S S+ 
Sbjct: 820  SSNSSDSSNSSDSSDSSNSSD-SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878

Query: 343  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSP 402
             +  S + E + +       N        +      S +  ++ S+ +S+      +   
Sbjct: 879  SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938

Query: 403  EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTT 462
             +SS +   +  S+     + +      DSS S +   + + N+    D   +   S ++
Sbjct: 939  SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998

Query: 463  QQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYP 522
              SNS   S S +  +      ++++  SSN +D +      + S+ S +     +S+  
Sbjct: 999  DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058

Query: 523  HTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGD-QDTFHPSGGSHTTHGSESD 581
             + +S      + +   S    +    DS+ + N S S D  D+   S  S ++  S+S 
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118

Query: 582  GHSHGSQEGGANTTS 596
              S+ S    ++ +S
Sbjct: 1119 DSSNSSDSSDSSDSS 1133



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 75/440 (17%), Positives = 160/440 (36%), Gaps = 6/440 (1%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            +N  D   SN +D   SS SS    S+       +  +       DS   +DS+D   ++
Sbjct: 721  SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780

Query: 223  STSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWT 282
            ++S +  S+    + ++ +  D   S   S   D  D  SS  S +  + D +  +    
Sbjct: 781  NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840

Query: 283  QWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTI 342
              + S S+      ++ R    + + ++    + N                     +S  
Sbjct: 841  SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900

Query: 343  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSP 402
              + SS +  ++   +    +   E    +   +S  ++ ++ +S  +       ++ S 
Sbjct: 901  SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960

Query: 403  EDSSWTDFFNPISHPMGRGHQAGRRMDM-DSSHSITLQPTANPNTGL----VEDLDRTGP 457
            + S+ +D  +  S        +    D  DSS S     ++N +         D   +  
Sbjct: 961  DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020

Query: 458  LSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGY 517
             S ++  SNS   S S +  +      ++ +  SSN +D +      + S+ S +     
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080

Query: 518  TSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGD-QDTFHPSGGSHTTH 576
            +S    + +S      + +   S    +    DS+ + + S S D  D+   S  S +++
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140

Query: 577  GSESDGHSHGSQEGGANTTS 596
             S+S   S  S    ++ +S
Sbjct: 1141 SSDSSDSSESSDSSDSSDSS 1160



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 81/446 (18%), Positives = 166/446 (37%), Gaps = 40/446 (8%)

Query: 158 KGEYRTNPEDIY---PSNPTDDDVSSGSSSERS-STSGGYIFYTFSTVHPIPDEDSPWIT 213
           KG  +T  E +    P   ++     G S+  S S S GY  Y F     +  +D     
Sbjct: 411 KGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDD-KSMQGDDPNSSD 469

Query: 214 DSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFD 273
           +S     A S S N  S+  + +  +++ +D        G +DD+   +S  + +    +
Sbjct: 470 ESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGN 529

Query: 274 HTKQNQDWTQWN----PSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEH 329
               N D  + +     S S+      ++      D + + + + N + ++         
Sbjct: 530 GNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589

Query: 330 HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 389
             + ++  S+++  ++ SS + +++   +               K DS  +   ++ S  
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDS-----------SDSKSDSSKSESDSSDSDS 638

Query: 390 TSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLV 449
            S      ++ S ++S  +D  N         + +      DSS S +   ++N +    
Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSN-------SSNSSDSSDSSDSSDSSSSSDSSNSS---- 687

Query: 450 EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEG 509
            D   +   S +++ S+S   S S      D  +  +S   SSN +D +      N S+ 
Sbjct: 688 -DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD---SSNSSDS 743

Query: 510 STTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPS 569
           S +     +S    + +S      + +   S    +    DSN + N S S D      S
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS-----S 798

Query: 570 GGSHTTHGSESDGHSHGSQEGGANTT 595
             S +++ S+S   S  S    +N++
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSS 824



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 74/481 (15%), Positives = 186/481 (38%), Gaps = 25/481 (5%)

Query: 109  SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
            S+ S   +   ++S   + D ++ +D  N+ D   +    N   +         +N  D 
Sbjct: 835  SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894

Query: 169  YPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNT 228
              S+ + D  SS SS+   S+       +  + +   + +S   ++S+D   ++ +S+++
Sbjct: 895  SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954

Query: 229  ISAGWEPNEENEDERDRHLSFSG--SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNP 286
             S+    +  + D  D + S S   S   D  D   S+ S+      ++  + D +  + 
Sbjct: 955  DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014

Query: 287  SHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATP 346
            S ++ +    + +  +    + + + + + + ++          +  ++  S+ +  ++ 
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074

Query: 347  SSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSS 406
            SS + +++   +    +   +    +   DS  ++ ++ +S  +       ++ S + S 
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134

Query: 407  WTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSN 466
             +D  N                  DSS S     +++ +     D   +   S ++  SN
Sbjct: 1135 SSDSSNSSD-------------SSDSSESSDSSDSSDSSDS--SDSSDSSDSSDSSDSSN 1179

Query: 467  SQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKE 526
            S   S S +  +      ++ +  SS+ +D +      + S+ S +     ++    + +
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239

Query: 527  SRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHG 586
            S      +++   S          S+S+ + S S D+       G+   +GS+SD  S G
Sbjct: 1240 SSDSSDSSNSSDSS--------DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291

Query: 587  S 587
            S
Sbjct: 1292 S 1292



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 58/345 (16%), Positives = 123/345 (35%), Gaps = 10/345 (2%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            +N  D   SN +D   SS SS    S+                  DS   +DS+D   ++
Sbjct: 963  SNSSDSSDSNSSDSSDSSNSSDSSDSSDSS---------DSSDSSDSSNSSDSSDSSDSS 1013

Query: 223  STSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWT 282
             +S+++ S+    +  + D  D   S   S   D  D   S+ S+       +  + D +
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073

Query: 283  QWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTI 342
              + S  + E    + +  +    + + + + + + ++       +     ++  S+ + 
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133

Query: 343  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSP 402
             ++ SS + +++   E    +   +    +   DS S +  ++ S+++S       +   
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS-SDSSDSSDSSNSSDSSDSSDSSDS 1192

Query: 403  EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTT 462
             DSS +   +  S        +      DSS S     +   +             S  +
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252

Query: 463  QQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHS 507
              S+  S STS    E D    + +   + + +D      D NHS
Sbjct: 1253 SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 104/467 (22%), Positives = 163/467 (34%), Gaps = 60/467 (12%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWE 234
           ++G   ERSS S G     F+    T  P         T S   +P+TST + T      
Sbjct: 461 TTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGN 520

Query: 235 PNEENEDERDRHLS-FSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQW--------- 284
           P+        R  S  S  G   +    SS  +T P+      Q Q WTQ          
Sbjct: 521 PSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQ-WTQETGTTGEALL 579

Query: 285 -NPSHSNPEVLLQTTTRMTD--VDR------------NGTTAYEGNWNPEAHPPLIHHEH 329
            +PS+S  +++   T+  +   +DR            N +T +  + +P+  P +    H
Sbjct: 580 SSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGH 639

Query: 330 HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 389
            +  +T   + T ++    T  +T T     F    H      P++    +  T  A A 
Sbjct: 640 TQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAP 699

Query: 390 TSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMD----MDSSHSITLQPTANPN 445
           T     G TT +P  +       P SH    G   G  +     +  ++S+   P   P 
Sbjct: 700 TG---DGHTTQAPTTALQAA---PSSHDATLGPSGGTSLSKTGALTLANSVVSTP-GGPE 752

Query: 446 TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT---------TSTLTSSNRND 496
                    T P +        Q+ ST   G  +  +  +         T+T +SS  + 
Sbjct: 753 GQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASG 812

Query: 497 VTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVN 556
            T    +   + G TT      S   HT +S T +   SA   S G   V+ G ++S V 
Sbjct: 813 TTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASA---SHGAIPVSTGMASSIV- 868

Query: 557 RSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQ 603
                   TFHP+    +T G  +   S  S       T+   R  Q
Sbjct: 869 ------PGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQ 909



 Score = 33.9 bits (76), Expect = 0.53
 Identities = 103/465 (22%), Positives = 155/465 (33%), Gaps = 80/465 (17%)

Query: 170  PSNPTD-DDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNT 228
            P + TD   VS+G ++    TS        +T  P+ D  S    D+T  +P T TSS +
Sbjct: 2352 PLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTP-LPVTDTSSAS 2410

Query: 229  ISAGWEPNEENEDERDRHLSFSGSGIDDDEDFI---------SSTISTTPRAFDHTKQNQ 279
                             HL  +G       D           +ST   TP     T    
Sbjct: 2411 TGHA------------THLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSAS 2458

Query: 280  DW-TQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHS 338
               T   P      V    TT +   D +  +  +    P   P            T H+
Sbjct: 2459 TGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSP--------SSASTGHT 2510

Query: 339  TST-IQATPSSTTEETA---TQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPM 394
            T   +  TPS++T +T             R       T    + +   T+     TS   
Sbjct: 2511 TPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAAS 2570

Query: 395  QGRTTPSP---EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVED 451
             G  TP P     S+ T    P+  P+   + A       S+   T  P  + ++    D
Sbjct: 2571 TGHATPLPVTSTSSASTGDTTPL--PVTDTYSA-------STGQATPLPVTDTSSASTGD 2621

Query: 452  LDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGST 511
               T PL +T    ++ S ST H            + L  +N + V+ G   P H    +
Sbjct: 2622 ---TTPLPVT----DTSSASTGH-----------ATPLPVTNTSSVSTGHATPLHVTSPS 2663

Query: 512  TLLEGYTSHYPHTKES------RTFIPVTSAK---TGSFGVTAVTVGDSNSNVNRSL--- 559
            +   G+T+  P T  S       T +PVT A    TG      VT+  S S+ + +    
Sbjct: 2664 SASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPV 2723

Query: 560  --SGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTP 602
              +    T H +    T   S S GH+       A++ S    TP
Sbjct: 2724 TDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP 2768


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 99/424 (23%), Positives = 155/424 (36%), Gaps = 59/424 (13%)

Query: 205 PDEDSPWITDSTDRIPATSTSSNTISAGWEPNEEN---EDERDRHLSFSGSGIDDDEDFI 261
           P+ D+   T        TS SS T +    P+  +   E+    H S   +      D  
Sbjct: 4   PESDT---TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 60

Query: 262 SSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLL-QTTTRMTDVDRNGTTAYEGNWNPEA 320
           +++  +      H+ Q+   T   P+ S   VLL ++TT         TTA  G+     
Sbjct: 61  TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT-- 118

Query: 321 HPPLIHHE--HHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ---TPKE 375
            P L       H    +P +T +  +T SS   E +T      G+     +     TP  
Sbjct: 119 -PGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 177

Query: 376 DSHSTTGTAA----------ASAHTSHPMQGRTTPSPEDSSWTDFFNPISHP-MGRGHQA 424
             HSTT  ++          AS  TS P Q  TT      S     +P S   +  G ++
Sbjct: 178 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQES 237

Query: 425 GRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED---- 480
                   S   TL P +  ++G+VE   R    + + + + S + STS  GL+ +    
Sbjct: 238 TTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS-PGLQGESTAF 296

Query: 481 KDHPTTSTLTSSNRNDVTGGRRDP---NHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAK 537
           + HP ++  T S  +  T    +    + S GST      T+H+P               
Sbjct: 297 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP-----TTHFP--------------- 336

Query: 538 TGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSG 597
                 ++ T G S  +     S D     PS    TT G   +  +  SQ G  +TT+ 
Sbjct: 337 -----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAF 391

Query: 598 PIRT 601
           P  T
Sbjct: 392 PDST 395



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 74/344 (21%), Positives = 113/344 (32%), Gaps = 64/344 (18%)

Query: 170 PSNPTDDDVSSGSSSERSSTSGGYIFYTF----STVHPIPDEDSPWITDSTDRIPATSTS 225
           PS  +    SS  S++ + + G     +F    +T H  P       +  T   P ++TS
Sbjct: 205 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPG------STHTTLFPDSTTS 258

Query: 226 SNTISAGWEPNEENEDERDR--HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 283
           S  + A    +      R      S +  G+  +     ST   T  A  HT  +   T 
Sbjct: 259 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE-----STAFQTHPASTHTTPSPPSTA 313

Query: 284 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 343
             P         ++TT         TT +  +     H       H   + +  + S+  
Sbjct: 314 TAPVE-------ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 366

Query: 344 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR------ 397
           +T S  +EE++T   Q        G   T      +TT   +    TSH  QG       
Sbjct: 367 STTSGVSEESSTSHSQ-------PGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLD 419

Query: 398 TTPSP-----------------EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQP 440
           TTPSP                   S+ T  F+  S  +GR  ++        S   T  P
Sbjct: 420 TTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALP 479

Query: 441 TANPNTGLVE----------DLDRTGPLSMTTQQSNSQSFSTSH 474
            +    GL E            D T   + TT    S+  +TSH
Sbjct: 480 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 523


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 111/500 (22%), Positives = 175/500 (35%), Gaps = 39/500 (7%)

Query: 171 SNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPD-----EDSPWITDSTDRIPATSTS 225
           S+ T   VS+ + S  S TS G    T S  H          +S + T S+    AT++ 
Sbjct: 50  SSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSE 109

Query: 226 SNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN 285
           S+T S+G   +     E     S + +  + D    SS  ST   +   T  ++  T  N
Sbjct: 110 SSTTSSG--ASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATN 167

Query: 286 PSHSNPEVLLQTTTRM--TDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 343
              S       T T    + V    +TA     +  +        + E   T +   T  
Sbjct: 168 SESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTA-TNSESRTTSNGAGTAT 226

Query: 344 ATPSSTTEE---TATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTP 400
            + SSTT     TAT  E    +        +    + S  GTA  S  ++      T  
Sbjct: 227 NSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVT 286

Query: 401 SPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSM 460
           + E S+ +   N  ++       +G     +S  S T   ++  +T    +   T   + 
Sbjct: 287 NSESSTPSSGANTATNSESSTTSSGANTATNSDSSTT---SSGASTATNSESSTTSSGAS 343

Query: 461 TTQQSNSQSFSTSHEGLEEDKDHPT---TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGY 517
           T   S S + S+            T   TST T+S  + V+ G      SE STT     
Sbjct: 344 TATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGAS 403

Query: 518 TSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHG 577
           T+      ES T     S  T S   T  +  ++ +N   S++          G HTT  
Sbjct: 404 TA---TNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSH 460

Query: 578 SESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKK 637
           S S   S     G             +  W I L +L+++   + +   +     C +  
Sbjct: 461 SASTAVSEAKPGG------------SLVPWEIFLITLVSVVAAVGLFAGLFF---CVRNS 505

Query: 638 KLVINSGNGAVEDRKPSGLN 657
             + N+ N AV    P GLN
Sbjct: 506 LSLRNTFNTAV--YHPHGLN 523



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 63/272 (23%), Positives = 104/272 (38%), Gaps = 34/272 (12%)

Query: 329 HHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASA 388
           H E     + TST   T SS     A+          + G   T    S  +T T + S+
Sbjct: 17  HLEAATNSNETSTSANTGSSVISSGASTAT-------NSGSSVT---SSGVSTATISGSS 66

Query: 389 HTSHPM------QGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTA 442
            TS+ +      +  TT S   ++    F+ +S  +     +        + + T   ++
Sbjct: 67  VTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESS 126

Query: 443 NPNTGL--VEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT-----STLTSSNRN 495
            P++G     + D +   S  +  +NS S +TS E         +T     ST T+S  +
Sbjct: 127 TPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESS 186

Query: 496 DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNV 555
            V+       +SE STT     T+      ESRT        T +   TA     S ++ 
Sbjct: 187 TVSSRASTATNSESSTTSSGASTAT---NSESRT--------TSNGAGTATNSESSTTSS 235

Query: 556 NRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
             S + + ++  PS G+ T   SES   S G+
Sbjct: 236 GASTATNSESSTPSSGAGTATNSESSTTSSGA 267


>gi|61743978 stabilin 1 precursor [Homo sapiens]
          Length = 2570

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 5/102 (4%)

Query: 23   DLNITCRFAGVFHVEK-NGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGF 81
            DL+   + AGVFH++  +G Y ++ +EA   C+A  + L +  Q+  A  +GF  C  G+
Sbjct: 2199 DLHFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGW 2258

Query: 82   I-EGHVVIPRIHPNSICAANNTGVYILTSN---TSQYDTYCF 119
            +  G    P + P + C     G+  L +    + ++D YCF
Sbjct: 2259 LANGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCF 2300


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 83/389 (21%), Positives = 136/389 (34%), Gaps = 52/389 (13%)

Query: 246  HLSFSGSGIDDDE----DFISSTISTTPRAFDHTKQNQDWTQWNP---SHSNPEVLLQTT 298
            H   SGS   D E    D  + ++S   +A  H + +Q+ T+      S  +   L Q +
Sbjct: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 2419

Query: 299  TRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS-----TIQATP-SSTTEE 352
            T       +G T         +H           + + HSTS     TI   P SS+   
Sbjct: 2420 THEQSESAHGRTGTSTGGRQGSH------HKQARDSSRHSTSQEGQDTIHGHPGSSSGGR 2473

Query: 353  TATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFN 412
              +  EQ      H G        SH +  T+   +  SH   G  + S +  +     +
Sbjct: 2474 QGSHYEQLVDRSGHSG--------SHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGD 2525

Query: 413  PISHPMGRGHQAGRRMDMDSSHSITLQPTANPNT------GLVEDLDRTGPLSMTTQQSN 466
               H   R H+A  R D      +    +  P T         +D D  G    + + S 
Sbjct: 2526 GSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG 2585

Query: 467  SQS---FSTSHEGLEEDKDHPTT-------------STLTSSNRNDVT--GGRRDPNHSE 508
            S S     ++ E L +   HP +             S+  S  R+  T  GG+   +H +
Sbjct: 2586 SASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQ 2645

Query: 509  GSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHP 568
              ++  E + SH+  + +S     +   +  S    +   G S S  + +    +D+   
Sbjct: 2646 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 2705

Query: 569  SGGSHTTHGSESDGHSHGSQEGGANTTSG 597
            S  +H   GS    H   S  G +  TSG
Sbjct: 2706 SVSAHGQAGSHQQSHQE-SARGRSGETSG 2733



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 74/300 (24%), Positives = 103/300 (34%), Gaps = 50/300 (16%)

Query: 326 HHEHHEEEETPHSTSTIQATPSSTTE-------ETATQKEQWF---GNRWHEGYRQTPKE 375
           H   H+E+   H  S   +  S T         +TA+  EQ     G R   G++Q+   
Sbjct: 335 HPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS 394

Query: 376 DSHSTTGTA-AASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRG--------HQ--- 423
             HS TG   A+SA +    +G +     DS      +      G G        HQ   
Sbjct: 395 SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQEST 454

Query: 424 ---AGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPL--SMTTQQSNSQSFSTSHEGLE 478
              +G R     S    +     P++        TG    S   Q  +S   S S EG +
Sbjct: 455 RGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQD 514

Query: 479 EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT 538
             + HP +S            G R  +H E S        SH+ HT         + A  
Sbjct: 515 TIRGHPGSSR-----------GGRQGSHHEQSVNRSGHSGSHHSHTTSQGR----SDASH 559

Query: 539 GSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 598
           G  G  +     S    N   SGD  T H SG  H    S++D   H   + G   +SGP
Sbjct: 560 GQSGSRSA----SRQTRNEEQSGD-GTRH-SGSRHHEASSQADSSRH--SQVGQGQSSGP 611



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 84/461 (18%), Positives = 162/461 (35%), Gaps = 57/461 (12%)

Query: 169  YPSNPTDDDVSSGSSSERS---------STSGGYIFYTFSTVHPIPDEDSPWITDSTDRI 219
            +P +  +D    G S++RS         ++SGG    +       P E       S  + 
Sbjct: 3253 HPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERH----GSRHQQ 3308

Query: 220  PATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDE----DFISSTISTTPRAFDHT 275
             A S+  + I  G   +   +    RH   SGS   D E    +  + ++S   +A  H 
Sbjct: 3309 SADSSRHSGIPRGQASSAVRDS---RHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQ 3365

Query: 276  KQNQDWTQ---WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEE 332
            + +Q+  +      S  +   L Q +T       +G T         +H        HE+
Sbjct: 3366 QSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSH--------HEQ 3417

Query: 333  EETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSH 392
                   S  Q    +      + +    G+ + +   ++    SH +  T+   +  S 
Sbjct: 3418 ARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASR 3477

Query: 393  PMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQ-------PTANPN 445
               G  + S +  +     +   H     H+A  + D  S HS + Q        + N  
Sbjct: 3478 GQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQAD-SSRHSQSGQGQSAGPRTSRNQG 3536

Query: 446  TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKD---HPTT---------STLTSSN 493
            + + +D D  G    + + S S S +      E+ +D   HPT+          +  SS 
Sbjct: 3537 SSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSR 3596

Query: 494  RN------DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVT 547
            ++      + +GG+   +H +  ++  E + SH+  + +S     +   +  S    +  
Sbjct: 3597 QSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH 3656

Query: 548  VGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQ 588
             G S S  + S    +D+   S  +H   G     H   ++
Sbjct: 3657 RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTR 3697



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 77/361 (21%), Positives = 124/361 (34%), Gaps = 42/361 (11%)

Query: 246  HLSFSGSGIDDDE----DFISSTISTTPRAFDHTKQNQDWTQWNP---SHSNPEVLLQTT 298
            H   SGS   D E    D  + ++S   +A  H + +Q+ T+      S  +   L Q +
Sbjct: 3656 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 3715

Query: 299  TRMTDVDRNG-----TTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE-E 352
            T       +G     T   +G+ + +A     H    E ++T      I+  P S     
Sbjct: 3716 THEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDT------IRGHPGSRRGGR 3769

Query: 353  TATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFN 412
              +  EQ      H G        SH +  T+   +  SH   G  + S E  +     +
Sbjct: 3770 QGSYHEQSVDRSGHSG--------SHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGD 3821

Query: 413  PISHPMGRGHQAGRRMDMDSSHSITLQPTA-----NPNTGLVEDLDRTGPLSMTTQQSNS 467
               H   R H+A  + D  S HS + Q  +     +   G     D          +  S
Sbjct: 3822 GSRHSGSRHHEASTQAD-SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRS 3880

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
            +S S +H G   ++    +    SS+R+  +  +  P  S+ ST    G+ S        
Sbjct: 3881 ESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAY 3940

Query: 528  RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSL--------SGDQDTFHPSGGSHTTHGSE 579
             + I    +   S      + G         L        S D D +  SG  H+ HGS 
Sbjct: 3941 HSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYD-YGESGFRHSQHGSV 3999

Query: 580  S 580
            S
Sbjct: 4000 S 4000



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 74/403 (18%), Positives = 137/403 (33%), Gaps = 52/403 (12%)

Query: 206  DEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTI 265
            D DS   ++ ++R   +++ ++  S   +    +   R  H   +G G   D    S T 
Sbjct: 3218 DSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTR 3277

Query: 266  STTPRAFDHTKQNQDWTQWNPS--HSNPEVLLQTTTRMTDVDRNGTTAY---EGNWNPEA 320
                 +      + +  + +P   H +       ++R + + R   ++      +W    
Sbjct: 3278 HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSG 3337

Query: 321  HPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQW-----FGNRWHEGYRQTPKE 375
                    H EE +T   +   QA P   + + + +          G+  ++       E
Sbjct: 3338 SQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSE 3397

Query: 376  DSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS 435
             +H  T T+      SH  Q R   S   S+  +  + I     RGH    R     SH 
Sbjct: 3398 SAHGRTRTSTGRRQGSHHEQARD--SSRHSASQEGQDTI-----RGHPGSSRRGRQGSH- 3449

Query: 436  ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRN 495
                          + +DR+G        + SQ  S +  G    +   + S  T ++  
Sbjct: 3450 ------------YEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR---SASRQTRNDEQ 3494

Query: 496  DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNV 555
               G R   +H   ++T  +  +S +  + + ++  P TS   GS               
Sbjct: 3495 SGDGSRHSWSHHHEASTQAD--SSRHSQSGQGQSAGPRTSRNQGS--------------- 3537

Query: 556  NRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 598
              S+S D D+   S  S    GS S  H   +QE   + +  P
Sbjct: 3538 --SVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHP 3578



 Score = 36.6 bits (83), Expect = 0.081
 Identities = 64/304 (21%), Positives = 105/304 (34%), Gaps = 43/304 (14%)

Query: 329 HHEE--EETPHSTS-----TIQATP-SSTTEETATQKEQWFGNRWHEGYRQTPKEDSHST 380
           HHE+  + + HS S     TI+  P SS      +  EQ      H G        SH +
Sbjct: 496 HHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSG--------SHHS 547

Query: 381 TGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQP 440
             T+   +  SH   G  + S +  +     +   H   R H+A  + D      +    
Sbjct: 548 HTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQ 607

Query: 441 TANPNT------GLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKD------------ 482
           ++ P T       + +D D  G    + + S S S +      E+ +D            
Sbjct: 608 SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDR 667

Query: 483 ----HPTTSTLTSSNRN--DVTGGRRDPNHSEGSTTLLEGYTS-HYPHTKESRTFIPVTS 535
               H   S+  S  R+  + + G+   +H +  ++  E + S H   + +S        
Sbjct: 668 AGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH 727

Query: 536 AKTGSFGVTAVTVGDSNSNVNRS--LSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGAN 593
            +  S    +   G S S    S   S D DT   SG     H  +S   S   + G  +
Sbjct: 728 GQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERS 787

Query: 594 TTSG 597
             SG
Sbjct: 788 RRSG 791



 Score = 36.6 bits (83), Expect = 0.081
 Identities = 74/409 (18%), Positives = 126/409 (30%), Gaps = 43/409 (10%)

Query: 219  IPATSTSSNTISAG-WEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ 277
            IP    SS    +G W  +     + + H        + D   +S      P    H + 
Sbjct: 1049 IPRRQASSAVRDSGHWGSSGSQASDSEGHSE------ESDTQSVSGHGQDGPHQQSHQES 1102

Query: 278  NQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPH 337
             +DW+      S   +   +T   ++     T    G      H        H   +   
Sbjct: 1103 ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ--E 1160

Query: 338  STSTIQATPSSTTE-ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG 396
               TI+A P S       +  EQ      H G        SH +  T+   +  SH   G
Sbjct: 1161 GQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSG--------SHHSHTTSQGRSDASHGQSG 1212

Query: 397  RTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNT----GLVEDL 452
              + S +        +   H   R H+A    D      +  + ++   T    G     
Sbjct: 1213 SRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQ 1272

Query: 453  DRTGPLSMTTQQSNSQSFSTSHEG--LEEDKD----------------HPTTSTLTSSNR 494
            D          +  S S S +H G   E+ +D                H   S+  S   
Sbjct: 1273 DSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTH 1332

Query: 495  NDVTG--GRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSN 552
            +  +   G+   +H +  ++  E + S +  + +S     +   +  S    +   G S 
Sbjct: 1333 HTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSG 1392

Query: 553  SNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 601
            S V  S    +D+   S  +H   G     H   S  G +  +SG  R+
Sbjct: 1393 SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE-SARGQSGESSGRSRS 1440



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 97/469 (20%), Positives = 163/469 (34%), Gaps = 74/469 (15%)

Query: 170  PSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDED----SPWITDSTDRIPATSTS 225
            P +  +D  S G S+E S  SG     T S       ++    SP     +    +  +S
Sbjct: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692

Query: 226  SNTISAGWEPNEENEDERDRHLSFSGSGIDDDE----DFISSTISTTPRAFDHTKQNQDW 281
            +++ +   + +    D  +R    SGS   D E    +  + ++S   +A  H + +Q+ 
Sbjct: 1693 TDSGTGRRQDSSVVGDSGNR--GSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQES 1750

Query: 282  TQWNP---SHSNPEVLLQTTTRMTDVDRNGTTAYE-GNWNPEAHPPLIHHEHHEEEETPH 337
            T+      S  +   L Q +T       +G T    G      H        H   +   
Sbjct: 1751 TRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQ--E 1808

Query: 338  STSTIQATP-SSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG 396
               TI+  P SS      +  EQ   +  H G        SH +  T+   +  S    G
Sbjct: 1809 GQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG--------SHHSHTTSQERSDVSRGQSG 1860

Query: 397  RTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNT------GLVE 450
              + S +  +     +   H   R H+A  R D      +    ++ P T       + +
Sbjct: 1861 SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ 1920

Query: 451  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKD----------------HPTTSTLTSSNR 494
            D D  G    + + S S S +      E+ +D                H   S+  S  R
Sbjct: 1921 DSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR 1980

Query: 495  NDVTG--GRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTG-SFGVTAVTVGDS 551
            +  +   G+   +H +  ++  E + SH  H  +S      +S  +G   G  +  V DS
Sbjct: 1981 HTESSSRGQAASSHEQARSSAGERHGSH--HQLQSAD----SSRHSGIGHGQASSAVRDS 2034

Query: 552  NSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS--QEGGANTTSGP 598
                +R  SG Q              S+S+GHS  S  Q   A   +GP
Sbjct: 2035 G---HRGYSGSQ-------------ASDSEGHSEDSDTQSVSAQGKAGP 2067



 Score = 33.1 bits (74), Expect = 0.90
 Identities = 96/459 (20%), Positives = 160/459 (34%), Gaps = 98/459 (21%)

Query: 151 DGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSS-ERSSTSGGYIFYTFSTVHPIPDEDS 209
           DGTR+     +  + +     +     V  G SS  R+S + G      S+V    D DS
Sbjct: 579 DGTRHSGSRHHEASSQ---ADSSRHSQVGQGQSSGPRTSRNQG------SSVSQ--DSDS 627

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTP 269
              ++ ++R   +++ ++  SA  +  + +   R  H   +G G   D    S T  T  
Sbjct: 628 QGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHT-- 685

Query: 270 RAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEH 329
                  QN    Q   SH           R +  +R+G+                 H+ 
Sbjct: 686 -------QNSSSGQAASSHEQ--------ARSSAGERHGS----------------RHQL 714

Query: 330 HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKE------DSHSTTGT 383
              + + HS  T     SS   ++        G+R   G + T  E      D+ S +G 
Sbjct: 715 QSADSSRHS-GTGHGQASSAVRDS--------GHRGSSGSQATDSEGHSEDSDTQSVSGH 765

Query: 384 AAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTAN 443
             A  H     +     S E S  +  F          +Q       +SSH  T      
Sbjct: 766 GQAGHHQQSHQESARDRSGERSRRSGSFL---------YQVSTHKQSESSHGWT-----G 811

Query: 444 PNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTL--------TSSNRN 495
           P+TG+     R G  S   Q  ++   S S +G +  + HP +S           S +R+
Sbjct: 812 PSTGV-----RQG--SHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRS 864

Query: 496 DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS-FGVTAVTVGDSNSN 554
             +G       S+G +    G +        SRT      ++ GS    +      S+++
Sbjct: 865 GHSGSHHSHTTSQGRSDASRGQSGS---RSASRTTRNEEQSRDGSRHSGSRHHEASSHAD 921

Query: 555 VNRSLSGDQDTFHPSG-----GSHTTHGSESDGHSHGSQ 588
           ++R     Q     S      GS  +  S+S+GHS  S+
Sbjct: 922 ISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960



 Score = 33.1 bits (74), Expect = 0.90
 Identities = 84/408 (20%), Positives = 138/408 (33%), Gaps = 61/408 (14%)

Query: 206  DEDSPWITDSTDRIPATSTSSNTISAGWEPNEE-NEDERDRHLSFSGSGIDDDEDFISST 264
            D DS   ++ ++R    S S N + + WE + + +      H   +G G   D    S T
Sbjct: 1921 DSDSQGHSEDSERWSG-SASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGT 1979

Query: 265  ISTTPR-----AFDHTKQNQDWTQWNPSH-------SNPEVLLQTTTRMTDVDRNGTTAY 312
              T        A  H +      + + SH       S+    +      + V  +G   Y
Sbjct: 1980 RHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGY 2039

Query: 313  EGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATP--SSTTEETATQKEQWFGNRWHEGYR 370
             G+   ++        H E+ +T   ++  +A P   S  E    Q  +  G      Y+
Sbjct: 2040 SGSQASDSEG------HSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQ 2093

Query: 371  QTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDM 430
             +  E S ST G +A S   +   QG      +DSS           + RGH    R   
Sbjct: 2094 VSTHEQSESTHGQSAPS---TGGRQGSHYDQAQDSSRHSASQEGQDTI-RGHPGPSRGGR 2149

Query: 431  DSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLT 490
              SH               + +DR+G        + SQ  S +  G    +   + S  T
Sbjct: 2150 QGSHQ-------------EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR---SASRKT 2193

Query: 491  SSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGD 550
                    G R   +H   +++  +  +S +    + ++  P TS   GS          
Sbjct: 2194 YDKEQSGDGSRHSGSHHHEASSWAD--SSRHSLVGQGQSSGPRTSRPRGS---------- 2241

Query: 551  SNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 598
                   S+S D D+   S  S    GS S  H   +QE   + +  P
Sbjct: 2242 -------SVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHP 2282



 Score = 33.1 bits (74), Expect = 0.90
 Identities = 72/304 (23%), Positives = 102/304 (33%), Gaps = 56/304 (18%)

Query: 323  PLIHHE----HHEEEETPHSTSTIQATPSSTTEETAT--QKEQWFGNRWHEGYRQTPKED 376
            P  HHE    H    E+   + T  A  SS  +  ++  Q     G R    ++Q+    
Sbjct: 2282 PRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2341

Query: 377  SHSTTGTA-AASAHTSHPMQGRTTPSPEDSSW----TDFFNPISHPMG-----------R 420
             HS  G   A+SA      +G +     DS      +D  +  +H              R
Sbjct: 2342 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTR 2401

Query: 421  GHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPL------SMTTQQSNSQSFSTSH 474
            G  AGR      S S   Q + +  +       RTG        S   Q  +S   STS 
Sbjct: 2402 GRSAGR---SGRSGSFLYQVSTHEQSESAH--GRTGTSTGGRQGSHHKQARDSSRHSTSQ 2456

Query: 475  EGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVT 534
            EG +    HP +S+           G R  +H E          SH+ HT  S+     +
Sbjct: 2457 EGQDTIHGHPGSSS-----------GGRQGSHYEQLVDRSGHSGSHHSHT-TSQGRSDAS 2504

Query: 535  SAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANT 594
               +GS   +  T  D  S          D    SG  H  H + S   S G  + G   
Sbjct: 2505 HGHSGSRSASRQTRNDEQSG---------DGSRHSGSRH--HEASSRADSSGHSQVGQGQ 2553

Query: 595  TSGP 598
            + GP
Sbjct: 2554 SEGP 2557



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 65/317 (20%), Positives = 104/317 (32%), Gaps = 53/317 (16%)

Query: 313  EGNWNPEAHPP-LIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ 371
            +G+ +P +H      H H  +      T   Q +       +  Q     G R    ++Q
Sbjct: 2601 DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2660

Query: 372  TPKEDSHSTTGTAAASA---HTSHPMQGRTTPSPED--SSWTDFFNPISHPMGRGHQ--- 423
            +     HS  G   AS+    + H     +  S  +  S  +D  +  +H     HQ   
Sbjct: 2661 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH 2720

Query: 424  ---AGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQS------NSQSFSTSH 474
               A  R    S HS +     + +         TGP +   Q S      +S   S S 
Sbjct: 2721 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQ 2780

Query: 475  EGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVT 534
            +G +  + HP +S            G R   H E S        SH+ HT  S+     +
Sbjct: 2781 DGQDTIRGHPGSSR-----------GGRQGYHHEHSVDSSGHSGSHHSHTT-SQGRSDAS 2828

Query: 535  SAKTGSFGVTAVTVGDSNSNVNRSLSGDQD---------TFHPSG--------------G 571
              ++GS   +  T  +  S      SG +          + H                 G
Sbjct: 2829 RGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 2888

Query: 572  SHTTHGSESDGHSHGSQ 588
            S  +  S+S+GHS  S+
Sbjct: 2889 SSVSQDSDSEGHSEDSE 2905



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 61/297 (20%), Positives = 94/297 (31%), Gaps = 36/297 (12%)

Query: 313  EGNWNPEAHPP-LIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ 371
            +G+ +P +H      H H  +      T   Q +       +  Q     G R    ++Q
Sbjct: 2925 DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2984

Query: 372  TPKEDSHSTTGTA-AASAHTSHPMQGRTTPSPED----SSWTDFFNPISHPMGRGHQ--- 423
            +     HS  G   A+SA      +G +     D    S  +D  +  +H     HQ   
Sbjct: 2985 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH 3044

Query: 424  ---AGRRMDMDSSHS------ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSH 474
               A  R    S HS      ++    +  + G      R    S   Q  +S   S S 
Sbjct: 3045 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQ 3104

Query: 475  EGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVT 534
             G +  + HP +S            G R   H E S        SH+ HT         +
Sbjct: 3105 YGQDTIRGHPGSSR-----------GGRQGYHHEHSVDSSGHSGSHHSHTTSQGR----S 3149

Query: 535  SAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSH---TTHGSESDGHSHGSQ 588
             A  G  G  + +    N   +   S    + H    +H   + H     G S GS+
Sbjct: 3150 DASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR 3206



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 53/239 (22%), Positives = 83/239 (34%), Gaps = 43/239 (17%)

Query: 370  RQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMD 429
            RQ+    + +++G  AAS+H     Q R++      S        S   G GH       
Sbjct: 2948 RQSGTRHTQTSSGGQAASSHE----QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAV 3003

Query: 430  MDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTL 489
             DS H       A+ N G  ED D        TQ  ++   + SH+   ++         
Sbjct: 3004 RDSGHRGYSGSQASDNEGHSEDSD--------TQSVSAHGQAGSHQQSHQE--------- 3046

Query: 490  TSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVG 549
            ++  R+  T G         S + L   ++H           P T  + GS    A    
Sbjct: 3047 SARGRSGETSGH--------SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQA---Q 3095

Query: 550  DSNSNVNRSLSGDQDTFHPSG------GSHTTHGSESDG-----HSHGSQEGGANTTSG 597
            DS+ +       D    HP        G H  H  +S G     HSH + +G ++ + G
Sbjct: 3096 DSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG 3154


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 112/486 (23%), Positives = 185/486 (38%), Gaps = 85/486 (17%)

Query: 169  YPSNPTDDDVSSGSSSERSS------------TSGGYIFYTFSTVHPIPDEDSPWITDST 216
            +PS+ T   VS  S++  SS            T+   +    +T H      SP  T++T
Sbjct: 4374 FPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH-----SSPGSTETT 4428

Query: 217  DRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTK 276
              +P  +T+S  + A   P   +       LS +GS     E       STT +++ ++K
Sbjct: 4429 -LLPDNTTASGLLEAS-TPVHSSTGSPHTTLSPAGSTTRQGE-------STTFQSWPNSK 4479

Query: 277  QNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETP 336
               D T   P+ ++  V L TT+  +      TT +  +               EE  T 
Sbjct: 4480 ---DTTPAPPTTTSAFVELSTTSHGSP-SSTPTTHFSASSTTLGRS--------EESTTV 4527

Query: 337  HSTSTIQAT-PSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQ 395
            HS+    AT PS     T+   E+        G  QT      +TT      + TSH   
Sbjct: 4528 HSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSST 4587

Query: 396  GRTTPSPEDSSWTDFFNPISHPMGRGHQA-----------GRRMDMDSSHSI-----TLQ 439
              T  S   ++      P S+    G  A           GR  +  +SHS      T+ 
Sbjct: 4588 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 4647

Query: 440  PTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDK----DHPTTSTLTSSNRN 495
              A   T ++     T P+S  + ++ +   ST+  GL E        P+++  T  + +
Sbjct: 4648 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSAS 4707

Query: 496  DVTGGRRD---------------PNHSEGSTT-LLEGYTSHYPHTKESRTF-IPVTSAKT 538
              T GR +               P+ +  +T+ L+E  T+++     ++T   P +S  +
Sbjct: 4708 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 4767

Query: 539  G-------SFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGS-HTTHGSESDGHSHGSQEG 590
            G       S   T  T+    S  + +L  +  ++H S GS  TTH  ES   S  S+E 
Sbjct: 4768 GRSEESRTSHSSTTHTISSPPSTTS-ALVEEPTSYHSSPGSIATTHFPESSTTSGRSEES 4826

Query: 591  GANTTS 596
             A+ +S
Sbjct: 4827 TASHSS 4832



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 111/503 (22%), Positives = 177/503 (35%), Gaps = 78/503 (15%)

Query: 130  TSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSST 189
            T  T LP +   P T ++  +  T Y      R+    + P+  T   VS  SS+  S  
Sbjct: 2505 TETTTLPGS---PTTPSLSEKSTTFYTSP---RSPDATLSPATTTSSGVSEESSTSHSQP 2558

Query: 190  SGGYIF-YTFSTV------HPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDE 242
               +   +  ST       H      SP  TD+T  +PA++T+S        P++E+   
Sbjct: 2559 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT-LLPASTTTSG-------PSQESTT- 2609

Query: 243  RDRHLSFSGSGIDDDEDFISSTISTTPRAFD------HTKQNQDWTQWNPSHSNPEVLLQ 296
                 S S  G     D   S  STT  +F       H+      T   P  +    +++
Sbjct: 2610 -----SHSSPG---STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 2661

Query: 297  TTTRMTDVDRNGTTAYEGNWNPEAHP-PLIHHEHHEEEETPHSTSTIQATPSSTT---EE 352
             +TR+     + T +     +P +   P +  E    +  P ST T  + PS+ T   EE
Sbjct: 2662 ASTRV----HSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEE 2717

Query: 353  TATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFN 412
            + T         +H     TP      TT   A+S  + H  +     S  D+S T   +
Sbjct: 2718 STT---------YHRSPGSTP------TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2762

Query: 413  PISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE-----------DLDRTGPLSMT 461
              S   GRG     R+   S+  IT  P +    GL E                 P SMT
Sbjct: 2763 AHSTTSGRGESTTSRISPGST-EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 2821

Query: 462  TQQSNSQS-FSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSE------GSTTLL 514
            +     +S  S S  G       P ++T    +    T     P  +E       +TT +
Sbjct: 2822 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSV 2881

Query: 515  EGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHT 574
             G      H++ + T   + +  + + G+T  +     S  +              G  +
Sbjct: 2882 RGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES 2941

Query: 575  THGSESDGHSHGSQEGGANTTSG 597
            T    S G +  +     +TTSG
Sbjct: 2942 TTFPSSSGSTGTTLSPARSTTSG 2964



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 119/513 (23%), Positives = 195/513 (38%), Gaps = 55/513 (10%)

Query: 120  NASAPPEEDCTSVTDLPNAFDG----PITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTD 175
            + SA  +E+ T+    P++ D     P T        T Y  +    + P   + ++ T 
Sbjct: 3128 STSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPS--STPTTHFSASSTT 3185

Query: 176  DDVSSGSSSERSS--TSGGYIFYTFSTVHPIPDED--SPWITDSTDR--IPATSTSSNTI 229
               S  S++  SS   +G  +F T S    +  E   SP  + ST+   +P ++T++   
Sbjct: 3186 LGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 3245

Query: 230  --SAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTI-STTPRAFDHTKQNQDWTQWNP 286
              S  +  +  + D      S + SG+ ++     S   ST   AF  +      +Q + 
Sbjct: 3246 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 3305

Query: 287  -SHSNP----EVLLQTTTRMTDVDRNGTTAYEGNWNPEAH--PPLIHHEHHEEEETP-HS 338
             SHS+P      L   +T  + +    TT + G  + E    P         E  TP HS
Sbjct: 3306 ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 3365

Query: 339  TSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRT 398
            ++    T  S    T  Q E      W      TP   +  TT      + TSH   G  
Sbjct: 3366 STGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPT--TTSAFVELSTTSH---GSP 3420

Query: 399  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPL 458
            + +P     T  F+  S  +GR  ++        + + T  P  +  +GLVE+       
Sbjct: 3421 SSTP-----TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSS 3475

Query: 459  SMTTQQSN-SQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP---NHSEGSTTLL 514
              +TQ  +  +S +TS  G E    H +T+   SS  +  +    +P   + S GST   
Sbjct: 3476 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTA-- 3533

Query: 515  EGYTSHYPHT------KESRTFIPVTSAKTGSF-----GVTAVTVGDSNSNVNRSLSGDQ 563
               T+H+P +       E  T    +   TG+        T+V +G+S +  +   SG  
Sbjct: 3534 ---TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT--SPISSGSM 3588

Query: 564  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            +T    G + T   SE     H S    A T S
Sbjct: 3589 ETTALPGSTTTPGLSEKSTTFHSSPRSPATTLS 3621



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 108/495 (21%), Positives = 172/495 (34%), Gaps = 48/495 (9%)

Query: 122  SAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSG 181
            ++P     T  T LP    G  T   ++   T +      R+    + P++ T   VS  
Sbjct: 1665 TSPISSGSTETTALP----GSTTTAGLSEKSTTFYSSP--RSPDTTLSPASTTSSGVSEE 1718

Query: 182  SSSERSSTSGGYIF-YTFSTVHPIPDEDS------PWITDSTDRIPATSTSS-NTISAGW 233
            S++  S     +   +  ST  P   ++S      P  TD+T    +T+ SS    S  +
Sbjct: 1719 STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTF 1778

Query: 234  EPNEENEDERDRHLSFSGSGIDDDEDFISSTI----STTPRAFDHTKQNQDWTQWNPSHS 289
              +  + +      + + SG+ +    + S+     +T   A   T+Q +  T  +   S
Sbjct: 1779 HSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSS 1838

Query: 290  NPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPHSTSTIQAT-P 346
               +    TT    V+ + T+    +  P  H           EE  T HS+    AT P
Sbjct: 1839 KDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP 1898

Query: 347  SSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSS 406
            S     T+   E+        G  QT      ST    +  + TSH     T  SP  ++
Sbjct: 1899 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 1958

Query: 407  WTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSN 466
                  P S+    G  A      DSS   T    +  +T      D TG + +  + + 
Sbjct: 1959 SALVEEPTSYHSSPGSTATTHFP-DSS---TTSGRSEESTASHSSQDATGTIVLPARSTT 2014

Query: 467  SQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVT--GGRRDPNHSEGSTTLLEGYTSHYPHT 524
            S     S           TTS ++S +       G    P  SE STT          H+
Sbjct: 2015 SVLLGES-----------TTSPISSGSMETTALPGSTTTPGLSEKSTTF---------HS 2054

Query: 525  KESRTFIPVTSAKTGSFGVTAV-TVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGH 583
                    ++ A T S GV+   T   S      + +    T  P    H+T    S G 
Sbjct: 2055 SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 2114

Query: 584  SHGSQEGGANTTSGP 598
            +  +    + TTSGP
Sbjct: 2115 TDTTLLPASTTTSGP 2129



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 102/446 (22%), Positives = 164/446 (36%), Gaps = 69/446 (15%)

Query: 102  TGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEY 161
            TG  +L + ++       + ++P        T LP    G  T   ++   T +      
Sbjct: 920  TGTIVLPARSTTSVLLGESTTSPISSGSMETTALP----GSTTTPGLSERSTTF--HSSP 973

Query: 162  RTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIF-YTFSTV------HPIPDEDSPWITD 214
            R+    + P++ T   VS  S++ RS     +   +  ST       H      SP  TD
Sbjct: 974  RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 1033

Query: 215  STDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDH 274
            +T  +PA++T+S        P++E+        S S SG     D   S  STT  +F  
Sbjct: 1034 TT-LLPASTTTSG-------PSQESTT------SHSSSG---STDTALSPGSTTALSF-- 1074

Query: 275  TKQNQDWTQWNPSHSNP----EVLLQTTTRMTDVDRNGTTAYEGNWNPE-------AHPP 323
                Q+ T +   HSNP      L   +T  + +    T  +    +P        +  P
Sbjct: 1075 ---GQESTTF---HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 1128

Query: 324  LIHHEHHEEEETPHSTSTIQATPSSTT---EETATQKEQWFGNRWHEGYRQTPKEDSHST 380
             +  E    +  P ST T  + PS+ T   EE+ T         +H     TP      T
Sbjct: 1129 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT---------YHRSPGSTP------T 1173

Query: 381  TGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQ- 439
            T   A+S  + H  +     S  D+S T   +  S   GRG     R+   S+   TL  
Sbjct: 1174 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 1233

Query: 440  PTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS-HEGLEEDKDHPTTSTLTSSNRNDVT 498
             T  P          + P S TT  S +   S    E     +  P ++  T S  +  T
Sbjct: 1234 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT 1293

Query: 499  GGRRDPNHSEGSTTLLEGYTSHYPHT 524
             G  + + +  S++     T+ +PH+
Sbjct: 1294 PGLSEESTTVYSSSRGSTETTVFPHS 1319



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 116/531 (21%), Positives = 184/531 (34%), Gaps = 66/531 (12%)

Query: 122  SAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSG 181
            ++P     T  T LP    G  T   ++   T +      R+    + P++ T   VS  
Sbjct: 3222 TSPISSGSTETTALP----GSTTTAGLSEKSTTFYSSP--RSPDTTLSPASTTSSGVSEE 3275

Query: 182  SSSERSSTSGGYIF-YTFSTVHPIPDEDS------PWITDSTDRIPATSTSS-----NTI 229
            S++  S     +   +  ST  P   ++S      P  TD+T    +T+ SS      T 
Sbjct: 3276 STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTF 3335

Query: 230  SAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTIS---TTPRAFDHTKQNQDWTQWNP 286
             +G  P          + + SG  ++      SST S   T   A   T+Q +  T  + 
Sbjct: 3336 HSG--PGSTETTLLPDNTTASGL-LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 3392

Query: 287  SHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPHSTSTIQA 344
             +S        TT    V+ + T+    +  P  H           EE  T HS+    A
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452

Query: 345  T-PSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPE 403
            T PS     T+   E+        G  QT       TT      + TSH     T  S  
Sbjct: 3453 TTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP 3512

Query: 404  DSSWTDFFNPISHPMGRGHQA-----------GRRMDMDSSHSI-----TLQPTANPNTG 447
             ++      P S+    G  A           GR  +  +SHS      T+   A   T 
Sbjct: 3513 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTS 3572

Query: 448  LVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKD-------HPTTSTLTSSNRNDVTGG 500
            ++     T P+S  + ++ +   ST+  GL E           P T+   +S  +     
Sbjct: 3573 VLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSE 3632

Query: 501  RRDPNHSEGSTTLLEGY--------------TSHYPHTKESRTFIPVTSAKTGSFGVTAV 546
                +HS   +T    +              TSH        T +P ++  +GS    + 
Sbjct: 3633 ESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS-SQEST 3691

Query: 547  TVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSG 597
            T   S+ + + +LS    T    G   TT  S S G +H +    + T+SG
Sbjct: 3692 TSHSSSGSTDTALSPGSTTALSFGQESTTFHS-SPGSTHTTLFPDSTTSSG 3741



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 119/515 (23%), Positives = 185/515 (35%), Gaps = 89/515 (17%)

Query: 109  SNTSQYDTYCFNASAPP---EEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNP 165
            S  S   T  F+AS+      E+ T+V   P A     T     R  T  V  GE  T+P
Sbjct: 1612 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG---TALFPTRSATS-VLVGEPTTSP 1667

Query: 166  EDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTS 225
                 S  T+     GS++    +     FY+           SP   D+T   PA++TS
Sbjct: 1668 ---ISSGSTETTALPGSTTTAGLSEKSTTFYS-----------SPRSPDTT-LSPASTTS 1712

Query: 226  SNTISAGWEPNEENEDERDRHLS-----FSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 280
            S         +EE+     R  S     F GS         S+   ++P + D T     
Sbjct: 1713 SGV-------SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS 1765

Query: 281  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNP----EAHPPLIHHEHHEEEETP 336
             T    S   PE    +TT  +      TT    N       EA  P+     H    +P
Sbjct: 1766 TTA---SSLGPE----STTFHSSPGSTETTLLPDNTTASGLLEASTPV-----HSSTGSP 1813

Query: 337  HSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG 396
            H+T  +    S+T +  +T  + W           + K+   +   T +A    S    G
Sbjct: 1814 HTT--LSPAGSTTRQGESTTFQSW----------PSSKDTMPAPPTTTSAFVELSTTSHG 1861

Query: 397  RTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTG 456
              + +P     T  F+  S  +GR  ++        + + T  P  +  +GLVE+     
Sbjct: 1862 SPSSTP-----TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH 1916

Query: 457  PLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP----NHSEGSTT 512
                +TQ  +    ST+    EE +   +++T T S+    T    +     + S GST 
Sbjct: 1917 SSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTA 1976

Query: 513  LLEGYTSHYPHT------KESRTFIPVTSAKTGSF-----GVTAVTVGDSNSNVNRSLSG 561
                 T+H+P +       E  T    +   TG+        T+V +G+S +  +   SG
Sbjct: 1977 -----TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT--SPISSG 2029

Query: 562  DQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
              +T    G + T   SE     H S    A T S
Sbjct: 2030 SMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLS 2064



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 112/531 (21%), Positives = 186/531 (35%), Gaps = 78/531 (14%)

Query: 102  TGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEY 161
            TG  +L + ++       + ++P        T LP    G  T   ++   T +      
Sbjct: 2003 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALP----GSTTTPGLSEKSTTF--HSSP 2056

Query: 162  RTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIF-YTFSTV------HPIPDEDSPWITD 214
            R+    + P++ T   VS  S++  S     +   +  ST       H      SP  TD
Sbjct: 2057 RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 2116

Query: 215  STDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFD- 273
            +T  +PA++T+S        P++E+        S S  G     D   S  STT  +F  
Sbjct: 2117 TT-LLPASTTTSG-------PSQESTT------SHSSPG---STDTALSPGSTTALSFGQ 2159

Query: 274  -----HTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHP-PLIHH 327
                 H+      T   P  +    +++ +TR+     + T +     +P +   P +  
Sbjct: 2160 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV----HSSTGSPRTTLSPASSTSPGLQG 2215

Query: 328  EHHEEEETPHSTSTIQATPSSTT---EETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTA 384
            E    +  P ST T  + PS+ T   EE+ T         +H     TP      TT   
Sbjct: 2216 ESTAFQTHPASTHTTPSPPSTATAPVEESTT---------YHRSPGSTP------TTHFP 2260

Query: 385  AASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANP 444
            A+S  + H  +     S  D+S T   +  S   GRG     R+   S+  IT  P +  
Sbjct: 2261 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST-EITTLPGSTT 2319

Query: 445  NTGLVE-----------DLDRTGPLSMTTQQSNSQS-FSTSHEGLEEDKDHPTTSTLTSS 492
              GL E                 P SMT+     +S  S S  G       P ++T    
Sbjct: 2320 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2379

Query: 493  NRNDVTGGRRDPNHSEGS------TTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAV 546
            +    T     P  +E +      TT + G      H++ + T   + +  + + G+T  
Sbjct: 2380 SEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 2439

Query: 547  TVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSG 597
            +     S  +              G  +T    S G +  +     +TTSG
Sbjct: 2440 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 103/479 (21%), Positives = 165/479 (34%), Gaps = 68/479 (14%)

Query: 173  PTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAG 232
            PTD  +S GS++  S      +   ++T H  P       +  T  +P  +T+S  + A 
Sbjct: 701  PTDTTLSPGSTTASS------LGPEYTTFHSRPG------STETTLLPDNTTASGLLEAS 748

Query: 233  WEPNEENEDERDRHLSFSGSGID----DDEDFISSTISTTPRAFDHTKQNQDWTQWNPSH 288
               +      R  H + S +G      +   F S   S   R    T  +        SH
Sbjct: 749  MPVHSST---RSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH 805

Query: 289  SNPEVLLQT-----TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 343
             +P  +  T     +T    V+ + T           H P         EE+  S S+  
Sbjct: 806  GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTT 865

Query: 344  ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQ-------- 395
             T SS    T+   E+        G   T      STT   +  +  SH  Q        
Sbjct: 866  HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 925

Query: 396  ----------GRTTPSP--EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTAN 443
                      G +T SP    S  T      +   G   ++        S + TL P + 
Sbjct: 926  PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 985

Query: 444  PNTGLVED--LDRTGPLS--------MTTQQSNSQSFSTSHE--GLEEDKDHPTTSTLTS 491
             ++G+ E+    R+ P S         TT    S+  +TSH   G  +    P ++T + 
Sbjct: 986  TSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 1045

Query: 492  SNRNDVT----GGRRDPNHSEGSTTLLE-GYTSHYPHTKESRTFIPVTSAKTGSFGVTAV 546
             ++   T     G  D   S GSTT L  G  S   H+    T   +    T S G+   
Sbjct: 1046 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIV-- 1103

Query: 547  TVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIP 605
               ++++ V+ S    + T  P+  S T+ G + +  +  +     +TT  P  T   P
Sbjct: 1104 ---EASTRVHSSTGSPRTTLSPA--SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 1157



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 101/458 (22%), Positives = 162/458 (35%), Gaps = 74/458 (16%)

Query: 102  TGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEY 161
            TG  +L + ++       + ++P        T LP    G  T   ++   T +      
Sbjct: 3560 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALP----GSTTTPGLSEKSTTF--HSSP 3613

Query: 162  RTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIF-YTFSTV------HPIPDEDSPWITD 214
            R+    + P++ T   VS  S++  S     +   +  ST       H      SP  TD
Sbjct: 3614 RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 3673

Query: 215  STDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFD- 273
            +T  +PA++T+S +              ++   S S SG     D   S  STT  +F  
Sbjct: 3674 TT-LLPASTTTSGS-------------SQESTTSHSSSG---STDTALSPGSTTALSFGQ 3716

Query: 274  -----HTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHP-PLIHH 327
                 H+      T   P  +    +++ +TR+     + T +     +P +   P +  
Sbjct: 3717 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV----HSSTGSPRTTLSPASSTSPGLQG 3772

Query: 328  EHHEEEETPHSTSTIQATPSSTT---EETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTA 384
            E    +  P ST T  + PS+ T   EE+ T         +H     TP      TT   
Sbjct: 3773 ESTAFQTHPASTHTTPSPPSTATAPVEESTT---------YHRSPGSTP------TTHFP 3817

Query: 385  AASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANP 444
            A+S  + H  +     S  D+S T   +  S   GRG     R+   S+  IT  P +  
Sbjct: 3818 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST-EITTLPGSTT 3876

Query: 445  NTGLVE-----------DLDRTGPLSMTTQQSNSQS-FSTSHEGLEEDKDHPTTSTLTSS 492
              GL E                 P SMT+     +S  S S  G       P ++T    
Sbjct: 3877 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 3936

Query: 493  NRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTF 530
            +    T     P  +E  TT+    T+     +E  TF
Sbjct: 3937 SEESTTVYSSSPGSTE--TTVFPRSTTTSVRREEPTTF 3972



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 127/541 (23%), Positives = 183/541 (33%), Gaps = 105/541 (19%)

Query: 109  SNTSQYDTYCFNASAPP---EEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNP 165
            S  S   T  F+AS+      E+ T+V   P A     T     R  T  V  GE  T+P
Sbjct: 4252 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG---TALFPTRSATS-VLVGEPTTSP 4307

Query: 166  EDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTS 225
                 S  T+     GS++    +     FY+           SP   D+T   PA++TS
Sbjct: 4308 ---ISSGSTETTALPGSTTTAGLSEKSTTFYS-----------SPRSPDTT-LSPASTTS 4352

Query: 226  SNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN 285
            S         +EE+     R  S   +           +  +T     H+      T  +
Sbjct: 4353 SGV-------SEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTA---SHSSPGSTDTTLS 4402

Query: 286  PSHSNPEVL-LQTTTRMTDVDRNGTTAYEGNWNP----EAHPPLIHHEHHEEEETPHST- 339
            P  +    L  ++TT  +      TT    N       EA  P+     H    +PH+T 
Sbjct: 4403 PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPV-----HSSTGSPHTTL 4457

Query: 340  ------------STIQATPSST----TEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGT 383
                        +T Q+ P+S        T T          H     TP     +++ T
Sbjct: 4458 SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTT 4517

Query: 384  AAASAHT----SHPMQGRTTPSPEDS--------SWTDFFNPIS----HPMGRGHQAGRR 427
               S  +    S P+   TTPSP  S        S T   +P S    H       +GR 
Sbjct: 4518 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRG 4577

Query: 428  MDMDSSHSITLQPTAN-PNT--GLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHP 484
             +  +SHS T    ++ P+T   LVE+         T+  S+  S +T+H          
Sbjct: 4578 EESTTSHSSTTHTISSAPSTTSALVEE--------PTSYHSSPGSTATTHFPDSSTTSGR 4629

Query: 485  TTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 544
            +  +  S +  D TG    P  S  S  L E  TS            P++S   GS   T
Sbjct: 4630 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTS------------PISS---GSMETT 4674

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQI 604
            A+      S     LS    TFH S  S  T    +   + G  E      S P+ T   
Sbjct: 4675 AL----PGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATT 4730

Query: 605  P 605
            P
Sbjct: 4731 P 4731



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 87/448 (19%), Positives = 162/448 (36%), Gaps = 50/448 (11%)

Query: 168  IYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWIT--DSTDRIPATSTS 225
            + P N T   +   S+   SST   +   + +       E + + +  +S D  PA  T+
Sbjct: 4429 LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTT 4488

Query: 226  SNT-ISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWT-- 282
            ++  +      +         H S S + +   E+  S+T+ ++P A   T      T  
Sbjct: 4489 TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEE--STTVHSSPVATATTPSPARSTTS 4546

Query: 283  ----QWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIH------------ 326
                +    HS+P      +T+      + TT+  G  +  +H    H            
Sbjct: 4547 GLVEESTTYHSSPG-----STQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSAL 4601

Query: 327  -HEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHS------ 379
              E      +P ST+T     SSTT   + +      ++   G    P   + S      
Sbjct: 4602 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 4661

Query: 380  -TTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHP----------MGRGHQAGRRM 428
             T+  ++ S  T+      TTP   + S T   +P S P          +GR  ++    
Sbjct: 4662 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVH 4721

Query: 429  DMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDK-DHPTTS 487
                + + T  P  +  +GLVE+         +TQ  +    ST+    EE +  H +T+
Sbjct: 4722 SSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 4781

Query: 488  TLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVT 547
               SS  +  +    +P     S   +   T+H+P +  +      ++A   S     +T
Sbjct: 4782 HTISSPPSTTSALVEEPTSYHSSPGSIA--TTHFPESSTTSGRSEESTASHSSPDTNGIT 4839

Query: 548  VGDSNSNVNRSLSGDQDTFHPSGGSHTT 575
               ++   +  ++ +  TF+ S GS  T
Sbjct: 4840 PLPAHFTTSGRIA-ESTTFYISPGSMET 4866



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 81/355 (22%), Positives = 126/355 (35%), Gaps = 65/355 (18%)

Query: 282 TQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE--GNWNPEAHP-----PLIHHEHHEEEE 334
           T ++   S    L    T  + V    TT++   G  +  A P     P +  E      
Sbjct: 282 TFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHS 341

Query: 335 TPHSTSTIQA----TPSSTTEETAT--------QKEQWFGNRWHEGYRQ--TPKEDS--- 377
            P ST T  +    TPSS   E+ T        +  +   N    G  +  TP   S   
Sbjct: 342 IPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGS 401

Query: 378 -HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSI 436
            H+T   ++++ H   P   ++ PS +D+S          P   G  +       + HS 
Sbjct: 402 PHTTLSPSSSTTHEGEPTTFQSWPSSKDTS----------PAPSGTTSAFVKLSTTYHS- 450

Query: 437 TLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRND 496
              P++ P T            S TT   + +S       +      P   + TS +  +
Sbjct: 451 --SPSSTPTTHF--------SASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEE 500

Query: 497 VTGGRRDPNHSEGSTTLLEGYTSHYP-------HTKESRTFIPVTSAKTGSFGVTAVTVG 549
            T   R P    GST      T H+P       H++ES TF   T+    S    + T  
Sbjct: 501 STAYHRSP----GST-----QTMHFPESSTTSGHSEESATFHGSTTHTKSS--TPSTTAA 549

Query: 550 DSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQI 604
            ++++ + SL G  +T H    S  +  SE    SH S +  A T      TP +
Sbjct: 550 LAHTSYHSSL-GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSV 603



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 78/321 (24%), Positives = 113/321 (35%), Gaps = 30/321 (9%)

Query: 287 SHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEA-HPPL------IHHEHHEEEETPHST 339
           S S     L  +T    +    TT Y    +P+  H P       +  E       P ST
Sbjct: 615 SGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGST 674

Query: 340 STIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRT- 398
            T  A P STT    +Q+     +    G   T      +T  +      T H   G T 
Sbjct: 675 HTT-AFPGSTTMPGLSQEST--ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTE 731

Query: 399 TPSPEDSSWTDFFNPISHPMGRGHQAGR--RMDMDSSHSITLQPTANPNTGLVEDLDRTG 456
           T    D++        S P+   H + R     +  + S T Q  +          D T 
Sbjct: 732 TTLLPDNTTASGLLEASMPV---HSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKD-TR 787

Query: 457 PLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEG 516
           P   TT  +  +  +TSH         PTT     S  + +       + S GST     
Sbjct: 788 PAPPTTTSAFVEPSTTSHGS---PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ---- 840

Query: 517 YTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSH-TT 575
            T H+P   ES T        T S   T  T+  + S  + +L  +  ++H S GS  TT
Sbjct: 841 -TMHFP---ESDTTSGRGEESTTSHSSTTHTISSAPSTTS-ALVEEPTSYHSSPGSTATT 895

Query: 576 HGSESDGHSHGSQEGGANTTS 596
           H  +S   S  S+E  A+ +S
Sbjct: 896 HFPDSSTTSGRSEESTASHSS 916



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 99/475 (20%), Positives = 160/475 (33%), Gaps = 78/475 (16%)

Query: 168  IYPSNPTDDDVSSGSSSERSSTSGG-----YIFYTFSTVH---PIPDEDSPWITDSTDRI 219
            + P++ T   +S  S++  SS+ G      +   T ++VH   P      P  T +T   
Sbjct: 1286 VSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT 1345

Query: 220  PATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQ 279
              ++TS  T  +   P      +     + + + + ++     S+  +T       +   
Sbjct: 1346 EDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST- 1404

Query: 280  DWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPH 337
              T      S P  L  ++T  T +  + TT           P L       +    +P 
Sbjct: 1405 --TSGLVGESTPSRLSPSSTETTTLPGSPTT-----------PSLSEKSTTFYTSPRSPD 1451

Query: 338  ST-STIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG 396
            +T S    T S  +EE++T   Q        G   T      +TT   +    TSH  QG
Sbjct: 1452 ATLSPATTTSSGVSEESSTSHSQ-------PGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 1504

Query: 397  RTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE----DL 452
             T  +    S T            G Q+            TL P     +GLVE      
Sbjct: 1505 STEATLSPGSTT--------ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH 1556

Query: 453  DRTGPLSMTTQQSNS-----QSFSTSHEGLEEDKD---------------------HPTT 486
              TG L  T   ++S     Q  ST+ +      D                      P++
Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616

Query: 487  STLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFI--PVTS-AKTGSFGV 543
            +  T  + +  T GR + + +  S+    G T+ +P    +   +  P TS   +GS   
Sbjct: 1617 TPTTHFSASSTTLGRSEESTTVHSSPGATG-TALFPTRSATSVLVGEPTTSPISSGSTET 1675

Query: 544  TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 598
            TA+      S     LS    TF+ S  S  T  S +   S G  E    + S P
Sbjct: 1676 TAL----PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1726



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 61/281 (21%), Positives = 100/281 (35%), Gaps = 23/281 (8%)

Query: 338  STSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR 397
            +++T  ++P S T   +       G        ++    +HST   A+ +          
Sbjct: 2326 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT 2385

Query: 398  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGP 457
               S   S+ T  F        RG +        +S   TL    +  +GL E+      
Sbjct: 2386 VYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 2445

Query: 458  LSMTTQQSNSQSFSTSHEGLEEDKDHPTTS----TLTSSNRNDVTG--GRRDPNH---SE 508
               +TQ     + +T+  G EE    P++S    T  S  R+  +G  G   P+    S 
Sbjct: 2446 SPASTQTGLPATLTTADLG-EESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSS 2504

Query: 509  GSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ----- 563
              TT L G  +    +++S TF   TS ++    ++  T   S  +   S S  Q     
Sbjct: 2505 TETTTLPGSPTTPSLSEKSTTFY--TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 2562

Query: 564  ------DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 598
                   T  P    H+T    S G +  +    + TTSGP
Sbjct: 2563 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2603



 Score = 34.3 bits (77), Expect = 0.40
 Identities = 67/291 (23%), Positives = 103/291 (35%), Gaps = 40/291 (13%)

Query: 335  TPHST-STIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHP 393
            +P +T S    T S  +EE++T   Q        G   T      +TT   +    TSH 
Sbjct: 4089 SPDATLSPATTTSSGVSEESSTSHSQ-------PGSTHTTAFPDSTTTSGLSQEPTTSHS 4141

Query: 394  MQGRTT---------------------PSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDS 432
             QG T                       SP D+  T      +   G    +        
Sbjct: 4142 SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTE-TTLLPDDTITSGLVEASTPTHSSTG 4200

Query: 433  SHSITLQPTANPNTGLVEDLD--RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLT 490
            S   TL P ++ +TGL E+    ++ P S  T  S   + +   E        P+++  T
Sbjct: 4201 SLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTT 4260

Query: 491  SSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFI--PVTS-AKTGSFGVTAVT 547
              + +  T GR + + +  S+    G T+ +P    +   +  P TS   +GS   TA+ 
Sbjct: 4261 HFSASSTTLGRSEESTTVHSSPGATG-TALFPTRSATSVLVGEPTTSPISSGSTETTAL- 4318

Query: 548  VGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 598
                 S     LS    TF+ S  S  T  S +   S G  E    + S P
Sbjct: 4319 ---PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 4366


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 70/293 (23%), Positives = 109/293 (37%), Gaps = 47/293 (16%)

Query: 330 HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ---TPKEDSHSTTGTAA- 385
           H    +P +T +  +T SS   E +T      G+     +     TP    HSTT  ++ 
Sbjct: 23  HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 82

Query: 386 ---------ASAHTSHPMQGRTTPSPEDSSWTDFFNPISHP-MGRGHQAGRRMDMDSSHS 435
                    AS  TS P Q  TT      S     +P S   +  G ++        S  
Sbjct: 83  GSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTH 142

Query: 436 ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED----KDHPTTSTLTS 491
            TL P +  ++G+VE   R    + + + + S + STS  GL+ +    + HP ++  T 
Sbjct: 143 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTP 201

Query: 492 SNRNDVTGGRRDP---NHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTV 548
           S  +  T    +    + S GST      T+H+P                     ++ T 
Sbjct: 202 SPPSTATAPVEESTTYHRSPGSTP-----TTHFP--------------------ASSTTS 236

Query: 549 GDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 601
           G S  +     S D     PS    TT G   +  +  SQ G  +TT+ P  T
Sbjct: 237 GHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDST 289



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 84/385 (21%), Positives = 129/385 (33%), Gaps = 67/385 (17%)

Query: 170 PSNPTDDDVSSGSSSERSSTSGGYIFYTF----STVHPIPDEDSPWITDSTDRIPATSTS 225
           PS  +    SS  S++ + + G     +F    +T H  P       +  T   P ++TS
Sbjct: 99  PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPG------STHTTLFPDSTTS 152

Query: 226 SNTISAGWEPNEENEDERDR--HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 283
           S  + A    +      R      S +  G+  +     ST   T  A  HT  +   T 
Sbjct: 153 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE-----STAFQTHPASTHTTPSPPSTA 207

Query: 284 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 343
             P         ++TT         TT +  +     H       H   + +  + S+  
Sbjct: 208 TAPVE-------ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 260

Query: 344 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR------ 397
           +T S  +EE++T   Q        G   T      +TT   +    TSH  QG       
Sbjct: 261 STTSGVSEESSTSHSQ-------PGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLD 313

Query: 398 TTPSP-----------------EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQP 440
           TTPSP                   S+ T  F+  S  +GR  ++        S   T  P
Sbjct: 314 TTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALP 373

Query: 441 TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGG 500
            +    GL E          TT  S+ +S  T+           +  + TS +R   T  
Sbjct: 374 GSTTTAGLSE--------KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 425

Query: 501 RRDPNHSEGSTTLLEGYTSHYPHTK 525
              P    GSTT + GY S  P ++
Sbjct: 426 TAFP----GSTT-MPGYHSIIPWSR 445


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 68/302 (22%), Positives = 105/302 (34%), Gaps = 44/302 (14%)

Query: 338  STSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR 397
            +T+T   +  ST   ++T    W           T    S +T  +  A+A T H     
Sbjct: 4226 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA 4285

Query: 398  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGP 457
            TTP+   S  T F +P           G    + +  S    PTA   T +      T  
Sbjct: 4286 TTPTVTSSKATPFSSP-----------GTATALPALRSTATTPTATSFTAIPSSSLGTTW 4334

Query: 458  LSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS------- 510
              ++   + + + ST+      +  H +T   T++     TG    P+ + G+       
Sbjct: 4335 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVP 4394

Query: 511  TTLLEGYT---SHYPHTKE------SRTFIPVTSAKT-------GSFGVTAVTVGDSNSN 554
            TT   G+T   S  P T        S T  P TS  T       G+     V    + + 
Sbjct: 4395 TTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTV 4454

Query: 555  VNRSLSGDQDTFHPSGGSH---------TTHG-SESDGHSHGSQEGGANTTSGPIRTPQI 604
               S++    +   SG +H         TTHG S S    H  +    + TSG + T  I
Sbjct: 4455 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 4514

Query: 605  PE 606
             E
Sbjct: 4515 TE 4516



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 67/302 (22%), Positives = 104/302 (34%), Gaps = 44/302 (14%)

Query: 338  STSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR 397
            +T+T   +  ST   ++T    W           T    S +T  +  A+A T H     
Sbjct: 3079 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA 3138

Query: 398  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGP 457
            TTP+   S  T F +P           G    + +  S    PTA   T +      T  
Sbjct: 3139 TTPTVTSSKATPFSSP-----------GTATALPALRSTATTPTATSFTAIPSSSLGTTW 3187

Query: 458  LSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS------- 510
              ++   + + + ST+      +  H +T   T++     TG    P+ + G+       
Sbjct: 3188 TRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVL 3247

Query: 511  TTLLEGYT---SHYPHTKE------SRTFIPVTSAKT-------GSFGVTAVTVGDSNSN 554
            TT   G+T   S  P T        S T  P T   T       G+     V    + + 
Sbjct: 3248 TTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTV 3307

Query: 555  VNRSLSGDQDTFHPSGGSH---------TTHG-SESDGHSHGSQEGGANTTSGPIRTPQI 604
               S++    +   SG +H         TTHG S S    H  +    + TSG + T  I
Sbjct: 3308 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 3367

Query: 605  PE 606
             E
Sbjct: 3368 TE 3369



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 90/439 (20%), Positives = 148/439 (33%), Gaps = 70/439 (15%)

Query: 122  SAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSG 181
            S   +   TSVT +P++  G          GT   Q          I+PS+  +   +S 
Sbjct: 4786 STATKSTATSVTPIPSSTLGTT--------GTLPEQTTTPVATMSTIHPSSTPETTHTST 4837

Query: 182  SSSERSSTSGGYIFYTFSTVHPIPDEDSPWI-------TDSTDRIPATSTSSNTISAGWE 234
              + +++T+      T ST  P     + WI         +T     T+T S+T    W 
Sbjct: 4838 VLTTKATTTRA----TSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWI 4893

Query: 235  PNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL 294
              E                        ++T ST   A   +     W    PS +   V 
Sbjct: 4894 LTELTTTA-------------------TTTASTGSTATPSSTPGTTWILTEPS-TTATVT 4933

Query: 295  LQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETA 354
            + T +  T       TA   + +  A  P +         +P + + + A  S+ T  TA
Sbjct: 4934 VPTGSTAT-ASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA 4992

Query: 355  TQ----KEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDF 410
            T          G  W     QT    +  +T T +++  T H     T  +    +    
Sbjct: 4993 TSFTAIPSSSLGTTWTR-LSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSV 5051

Query: 411  FNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSF 470
              P S P G  H    ++   ++   T  P+++P T L      T P+S         + 
Sbjct: 5052 ATPSSTP-GTAHTT--KVPTTTTTGFTATPSSSPGTALTPPT--TTPMS---------TM 5097

Query: 471  STSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTF 530
            ST H     +  H +T   T++     T     P+ + G+T +L   T+           
Sbjct: 5098 STIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTT----------- 5146

Query: 531  IPVTSAKTGSFGVTAVTVG 549
               T+A TGS    + T G
Sbjct: 5147 TATTTAATGSTATLSSTPG 5165



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 76/357 (21%), Positives = 124/357 (34%), Gaps = 56/357 (15%)

Query: 293  VLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLI----------HHEHHEEEETPHSTSTI 342
            +L + TT  T     G+TA   +    A PP +                   +P + +T+
Sbjct: 4722 ILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTL 4781

Query: 343  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGT-----AAASAHTSHPMQGR 397
                S+ T+ TAT       +    G   T  E + +   T      +++  T+H     
Sbjct: 4782 PVLTSTATKSTATSVTPIPSSTL--GTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVL 4839

Query: 398  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNT--GLVEDLDRT 455
            TT +    + +    P S P          +   ++ +    PTA P++  G    L   
Sbjct: 4840 TTKATTTRATSSTSTPSSTPGTTWILT--ELTTAATTTAATGPTATPSSTPGTTWILTEL 4897

Query: 456  GPLSMTTQQSNSQSFSTSHEG----LEEDKDH-----PTTSTLTSSNRN----------- 495
               + TT  + S +  +S  G    L E         PT ST T+S+             
Sbjct: 4898 TTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTT 4957

Query: 496  ----DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT----AVT 547
                 VT  +  P+ S G+ T L    S    T  + T    T+  + S G T    + T
Sbjct: 4958 ATTPTVTSSKATPSSSPGTATALPALRS----TATTPTATSFTAIPSSSLGTTWTRLSQT 5013

Query: 548  VGDSNSNVNRSLSGDQDTFHPS---GGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 601
               + +    + S   +T H S     + TT G+     +  S  G A+TT  P  T
Sbjct: 5014 TTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 5070



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 73/348 (20%), Positives = 119/348 (34%), Gaps = 66/348 (18%)

Query: 293  VLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLI----------HHEHHEEEETPHSTSTI 342
            +L + TT  T     G+TA   +    A PP +                   +P + +T+
Sbjct: 3575 ILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTL 3634

Query: 343  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSP 402
                S+ T+ TAT             +   P   +  TTGT      T+ PM   +T  P
Sbjct: 3635 PVLTSTATKSTAT------------SFTPIP-SFTLGTTGT--LPEQTTTPMATMSTIHP 3679

Query: 403  EDSSWTDFFNPISHPMGRGHQAGRRMDMDSS----------------HSITLQPTANPN- 445
              +  T   + +        +A   M   SS                 +    PTA P+ 
Sbjct: 3680 SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSS 3739

Query: 446  ----TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS-SNRNDVTGG 500
                T ++ +   T  +++ T  + + S + +  G        T   LTS +    V   
Sbjct: 3740 TPGTTWILTEPSTTATVTVPTGSTATASSTRATAG--------TLKVLTSTATTPTVISS 3791

Query: 501  RRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT----AVTVGDSNSNVN 556
            R  P+ S G+ T L    S    T  + T   VT+  + S G      + T   + +   
Sbjct: 3792 RATPSSSPGTATALPALRS----TATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMST 3847

Query: 557  RSLSGDQDTFHPS---GGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 601
             + S   +T H S     + TT  +     +  S  G A+TT  P  T
Sbjct: 3848 ATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTT 3895


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 126/578 (21%), Positives = 193/578 (33%), Gaps = 79/578 (13%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMD 431
            E S +TT +   S  T+    G   TT S E S  T               A    D  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---------GAETTTDST 578

Query: 432 SSHSITLQPTANPNTGLVEDLD-----------------RTGPLSMTTQQSNSQSFSTSH 474
                T   TA   T  V   D                  TG  + T   ++S++ + S 
Sbjct: 579 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638

Query: 475 EGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS-TTLLEGYTSHYPHTKE--SRTFI 531
           EG E      T S  T  +    TG  R    +EGS TT +    S    + E    T +
Sbjct: 639 EGSETTTVSTTDSETTMVS---TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695

Query: 532 PVTSAKTGSFGV----TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
            +T ++T         T +T  + +     S++G + T   + GS TT  S     + GS
Sbjct: 696 SITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTAS-----TEGS 750

Query: 588 QEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCI 625
           +   A+TT     T         +AS++     +A  I
Sbjct: 751 ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTI 788



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTITSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 104/472 (22%), Positives = 154/472 (32%), Gaps = 38/472 (8%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 263
               E +   T+S++   AT+  S T +A  E +E      +   + + S    +   +S+
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 264  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNG--TTAYEGNWNPEAH 321
            T S T  A   + +  + T  +   S    +  T +    V   G  TT      +    
Sbjct: 919  TGSETTTA---STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 322  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT 381
                  E          T+T     S TT  ++T  E    +        T  E S +TT
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 382  GTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITL 438
             T A S  T+    G   TT S E S  T      S              + +S S  T 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 439  QPTANPNTGLV-------EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS 491
              TA   T  V             G  + T   ++S++ + S  G E      T S  T+
Sbjct: 1096 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1155

Query: 492  SNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVT 544
             +             SE +TT  EG  +    T  S T           T++ +GS   T
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            A T G   S  + + S     F    GS TT  S +      +   G+ TT+
Sbjct: 1216 ACTTGSETSTPSSAGSETNTAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 107/503 (21%), Positives = 173/503 (34%), Gaps = 84/503 (16%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTS 225
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    +T+ S
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTK--VSTAGS 242

Query: 226 SNTIS-AGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQW 284
             T+S AG E    + ++ + + +F+       ED  ++T STT   F+ T  +   ++ 
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFT-------EDSKTTTASTT--GFETTAASTTGSEP 293

Query: 285 N-PSHSNPEVLLQTT-----TRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHS 338
              S    E  + +T     T+++      TT +               E          
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAG-----------SETIRASTVGSE 342

Query: 339 TSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRT 398
           T+T+  T S TT  +    E                  + STTG+   +A T       T
Sbjct: 343 TTTVSTTGSETTTASIMGSET----------------STDSTTGSETTTASTEG--SETT 384

Query: 399 TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPL 458
           T S E S  T                   +    S + T+  T +  T    +      +
Sbjct: 385 TASTEGSEATT------------------VSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 459 SMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYT 518
           S T  ++ + S   S   +    D  TT+  T  +             + GS T    YT
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-------TAGSETKT-AYT 478

Query: 519 SHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHT--- 574
           +    T  S T +  T+  T GS   TA T G   + V+ + S +  T    G  +T   
Sbjct: 479 TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGS-EMTTVSTEGSENTTVS 537

Query: 575 THGSESDGHSHGSQEGGANTTSG 597
           T GSE+   S    E    +T G
Sbjct: 538 TTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 102/446 (22%), Positives = 164/446 (36%), Gaps = 69/446 (15%)

Query: 102 TGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEY 161
           TG  +L + ++       + ++P        T LP    G  T   ++   T +      
Sbjct: 407 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALP----GSTTTPGLSERSTTF--HSSP 460

Query: 162 RTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIF-YTFSTV------HPIPDEDSPWITD 214
           R+    + P++ T   VS  S++ RS     +   +  ST       H      SP  TD
Sbjct: 461 RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 520

Query: 215 STDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDH 274
           +T  +PA++T+S        P++E+        S S SG     D   S  STT  +F  
Sbjct: 521 TT-LLPASTTTSG-------PSQESTT------SHSSSG---STDTALSPGSTTALSF-- 561

Query: 275 TKQNQDWTQWNPSHSNP----EVLLQTTTRMTDVDRNGTTAYEGNWNPE-------AHPP 323
               Q+ T +   HSNP      L   +T  + +    T  +    +P        +  P
Sbjct: 562 ---GQESTTF---HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 615

Query: 324 LIHHEHHEEEETPHSTSTIQATPSSTT---EETATQKEQWFGNRWHEGYRQTPKEDSHST 380
            +  E    +  P ST T  + PS+ T   EE+ T         +H     TP      T
Sbjct: 616 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT---------YHRSPGSTP------T 660

Query: 381 TGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQ- 439
           T   A+S  + H  +     S  D+S T   +  S   GRG     R+   S+   TL  
Sbjct: 661 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 720

Query: 440 PTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS-HEGLEEDKDHPTTSTLTSSNRNDVT 498
            T  P          + P S TT  S +   S    E     +  P ++  T S  +  T
Sbjct: 721 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT 780

Query: 499 GGRRDPNHSEGSTTLLEGYTSHYPHT 524
            G  + + +  S++     T+ +PH+
Sbjct: 781 PGLSEESTTVYSSSRGSTETTVFPHS 806



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 107/488 (21%), Positives = 172/488 (35%), Gaps = 59/488 (12%)

Query: 157  QKGEYRTNPEDIYPSNPTDDDVSSG----SSSERSSTSGGYIFYT--FSTVHPIPDEDS- 209
            Q   + ++P D   +   DD ++SG    S+   SST   +   T   ST   + +E + 
Sbjct: 1010 QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTT 1069

Query: 210  ----PWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTI 265
                P  +D+T   P T+ +   +S  +     +        S +  G  ++   + S+ 
Sbjct: 1070 FQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 1129

Query: 266  STTPRAFDHTKQNQDWTQWNP------SHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPE 319
              T  A   T+         P      S S     L  +T    +    TT Y    +P+
Sbjct: 1130 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD 1189

Query: 320  A--HPPLIHHEHHEEEET-----PHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQT 372
                P         EE T     P ST T  A P STT    +Q+     +    G   T
Sbjct: 1190 TTLSPASTTSSGVSEESTTSHSRPGSTHTT-AFPGSTTMPGVSQEST--ASHSSPGSTDT 1246

Query: 373  PKEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDSSWTDFFN---PISHPMGRGHQ---- 423
                  +T  +    + T H   G   TT  P++++ +       P+    G  H     
Sbjct: 1247 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 1306

Query: 424  AGRRMDMDSSHSITLQPTANPN-------TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEG 476
            AG       S +    P++          T    +L  T   S ++  +   S S++  G
Sbjct: 1307 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 1366

Query: 477  LEEDK----DHPTTSTLTSSNRNDVTGGRRDPN---HSEGSTTLLEGYTSHYPHTKESRT 529
              E+       P  +  T S     T G  + +   HS   +T     T H+P   ES T
Sbjct: 1367 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST----QTMHFP---ESST 1419

Query: 530  FIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGS-HTTHGSESDGHSHGSQ 588
                +     S   T  T+    S  + +L  +  ++H S GS  TTH  ES   S  S+
Sbjct: 1420 ASGRSEESRTSHSSTTHTISSPPSTTS-ALVEEPTSYHSSPGSIATTHFPESSTTSGRSE 1478

Query: 589  EGGANTTS 596
            E  A+ +S
Sbjct: 1479 ESTASHSS 1486



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 103/479 (21%), Positives = 165/479 (34%), Gaps = 68/479 (14%)

Query: 173 PTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAG 232
           PTD  +S GS++  S      +   ++T H  P       +  T  +P  +T+S  + A 
Sbjct: 188 PTDTTLSPGSTTASS------LGPEYTTFHSRPG------STETTLLPDNTTASGLLEAS 235

Query: 233 WEPNEENEDERDRHLSFSGSGID----DDEDFISSTISTTPRAFDHTKQNQDWTQWNPSH 288
              +      R  H + S +G      +   F S   S   R    T  +        SH
Sbjct: 236 MPVHSST---RSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH 292

Query: 289 SNPEVLLQT-----TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 343
            +P  +  T     +T    V+ + T           H P         EE+  S S+  
Sbjct: 293 GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTT 352

Query: 344 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQ-------- 395
            T SS    T+   E+        G   T      STT   +  +  SH  Q        
Sbjct: 353 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 412

Query: 396 ----------GRTTPSP--EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTAN 443
                     G +T SP    S  T      +   G   ++        S + TL P + 
Sbjct: 413 PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 472

Query: 444 PNTGLVED--LDRTGPLS--------MTTQQSNSQSFSTSHE--GLEEDKDHPTTSTLTS 491
            ++G+ E+    R+ P S         TT    S+  +TSH   G  +    P ++T + 
Sbjct: 473 TSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 532

Query: 492 SNRNDVT----GGRRDPNHSEGSTTLLE-GYTSHYPHTKESRTFIPVTSAKTGSFGVTAV 546
            ++   T     G  D   S GSTT L  G  S   H+    T   +    T S G+   
Sbjct: 533 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIV-- 590

Query: 547 TVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIP 605
              ++++ V+ S    + T  P+  S T+ G + +  +  +     +TT  P  T   P
Sbjct: 591 ---EASTRVHSSTGSPRTTLSPA--SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 644



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 106/480 (22%), Positives = 174/480 (36%), Gaps = 71/480 (14%)

Query: 109  SNTSQYDTYCFNASAPP---EEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNP 165
            S  S   T  F+AS+      E+ T+V   P A     T     R  T  V  GE  T+P
Sbjct: 1099 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG---TALFPTRSATS-VLVGEPTTSP 1154

Query: 166  EDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTS 225
                 S  T+     GS++    +     FY+           SP   D+T   PA++TS
Sbjct: 1155 ---ISSGSTETTALPGSTTTAGLSEKSTTFYS-----------SPRSPDTT-LSPASTTS 1199

Query: 226  SNTISAGWEPNEENEDERDRHLS-----FSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 280
            S         +EE+     R  S     F GS         S+   ++P + D T     
Sbjct: 1200 SGV-------SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS 1252

Query: 281  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNP----EAHPPLIHHEHHEEEETP 336
             T    S   PE    +TT  +      TT    N       EA  P+     H    +P
Sbjct: 1253 TTA---SSLGPE----STTFHSSPGSTETTLLPDNTTASGLLEASTPV-----HSSTGSP 1300

Query: 337  HSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG 396
            H+T  +    S+T +  +T  + W           + K+   +   T +A    S    G
Sbjct: 1301 HTT--LSPAGSTTRQGESTTFQSW----------PSSKDTMPAPPTTTSAFVELSTTSHG 1348

Query: 397  RTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTG 456
              + +P     T  F+  S  +GR  ++        + + T  P  +  +GLVE+     
Sbjct: 1349 SPSSTP-----TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH 1403

Query: 457  PLSMTTQQSNSQSFSTSHEGLEEDK-DHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLE 515
                +TQ  +    ST+    EE +  H +T+   SS  +  +    +P     S   + 
Sbjct: 1404 SSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIA 1463

Query: 516  GYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTT 575
              T+H+P +  +      ++A   S     +T   ++   +  ++ +  TF+ S GS  T
Sbjct: 1464 --TTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIA-ESTTFYISPGSMET 1520



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 78/321 (24%), Positives = 113/321 (35%), Gaps = 30/321 (9%)

Query: 287 SHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEA-HPPL------IHHEHHEEEETPHST 339
           S S     L  +T    +    TT Y    +P+  H P       +  E       P ST
Sbjct: 102 SGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGST 161

Query: 340 STIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRT- 398
            T  A P STT    +Q+     +    G   T      +T  +      T H   G T 
Sbjct: 162 HTT-AFPGSTTMPGLSQEST--ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTE 218

Query: 399 TPSPEDSSWTDFFNPISHPMGRGHQAGR--RMDMDSSHSITLQPTANPNTGLVEDLDRTG 456
           T    D++        S P+   H + R     +  + S T Q  +          D T 
Sbjct: 219 TTLLPDNTTASGLLEASMPV---HSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKD-TR 274

Query: 457 PLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEG 516
           P   TT  +  +  +TSH         PTT     S  + +       + S GST     
Sbjct: 275 PAPPTTTSAFVEPSTTSHGS---PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ---- 327

Query: 517 YTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSH-TT 575
            T H+P   ES T        T S   T  T+  + S  + +L  +  ++H S GS  TT
Sbjct: 328 -TMHFP---ESDTTSGRGEESTTSHSSTTHTISSAPSTTS-ALVEEPTSYHSSPGSTATT 382

Query: 576 HGSESDGHSHGSQEGGANTTS 596
           H  +S   S  S+E  A+ +S
Sbjct: 383 HFPDSSTTSGRSEESTASHSS 403



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 99/475 (20%), Positives = 160/475 (33%), Gaps = 78/475 (16%)

Query: 168  IYPSNPTDDDVSSGSSSERSSTSGG-----YIFYTFSTVH---PIPDEDSPWITDSTDRI 219
            + P++ T   +S  S++  SS+ G      +   T ++VH   P      P  T +T   
Sbjct: 773  VSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT 832

Query: 220  PATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQ 279
              ++TS  T  +   P      +     + + + + ++     S+  +T       +   
Sbjct: 833  EDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST- 891

Query: 280  DWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPH 337
              T      S P  L  ++T  T +  + TT           P L       +    +P 
Sbjct: 892  --TSGLVGESTPSRLSPSSTETTTLPGSPTT-----------PSLSEKSTTFYTSPRSPD 938

Query: 338  ST-STIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG 396
            +T S    T S  +EE++T   Q        G   T      +TT   +    TSH  QG
Sbjct: 939  ATLSPATTTSSGVSEESSTSHSQ-------PGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 991

Query: 397  RTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE----DL 452
             T  +    S T            G Q+            TL P     +GLVE      
Sbjct: 992  STEATLSPGSTT--------ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH 1043

Query: 453  DRTGPLSMTTQQSNS-----QSFSTSHEGLEEDKD---------------------HPTT 486
              TG L  T   ++S     Q  ST+ +      D                      P++
Sbjct: 1044 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1103

Query: 487  STLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFI--PVTS-AKTGSFGV 543
            +  T  + +  T GR + + +  S+    G T+ +P    +   +  P TS   +GS   
Sbjct: 1104 TPTTHFSASSTTLGRSEESTTVHSSPGATG-TALFPTRSATSVLVGEPTTSPISSGSTET 1162

Query: 544  TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 598
            TA+      S     LS    TF+ S  S  T  S +   S G  E    + S P
Sbjct: 1163 TAL----PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1213


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 104/472 (22%), Positives = 154/472 (32%), Gaps = 38/472 (8%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 263
               E +   T+S++   AT+  S T +A  E +E      +   + + S    +   +S+
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 264  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNG--TTAYEGNWNPEAH 321
            T S T  A   + +  + T  +   S    +  T +    V   G  TT      +    
Sbjct: 919  TGSETTTA---STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 322  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT 381
                  E          T+T     S TT  ++T  E    +        T  E S +TT
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 382  GTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITL 438
             T A S  T+    G   TT S E S  T      S              + +S S  T 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 439  QPTANPNTGLV-------EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS 491
              TA   T  V             G  + T   ++S++ + S  G E      T S  T+
Sbjct: 1096 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1155

Query: 492  SNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVT 544
             +             SE +TT  EG  +    T  S T           T++ +GS   T
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            A T G   S  + + S     F    GS TT  S +      +   G+ TT+
Sbjct: 1216 ACTTGSETSTPSSAGSETNTAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 103/472 (21%), Positives = 154/472 (32%), Gaps = 38/472 (8%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 263
               E +   T+S++   AT+  S T +A  E +E      +   + + S    +   +S+
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 264  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNG--TTAYEGNWNPEAH 321
            T S T  A   + +  + T  +   S    +  T +    V   G  TT      +    
Sbjct: 919  TGSETTTA---STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 322  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT 381
                  E          T+T     S TT  ++T  E    +        T  E S +TT
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 382  GTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITL 438
             T A S  T+    G   TT S E S  T      S              + +S S  T 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 439  QPTANPNTGLV-------EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS 491
              TA   T  V             G  + T   ++S++ + S  G E      T S  T+
Sbjct: 1096 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1155

Query: 492  SNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVT 544
             +             SE +TT  EG  +    T  S T           T++ +GS   T
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            A T G   S  + + S     F    GS +T  S +      +   G+ TT+
Sbjct: 1216 ACTTGSETSTPSSAGSETNTAF--IIGSESTIASTASLEPTATSLTGSETTT 1265



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 702  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 759

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 760  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 815

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 816  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 872

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 873  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 924

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 925  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 982

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 983  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1042

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1043 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1097

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1098 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1155

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1156 TASTTGSEMTT 1166



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 261 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 319

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 320 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 375

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 376 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 435

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 436 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 490

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 491 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 548

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 549 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 608

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 609 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 668

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 669 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 713

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 714 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 766



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 104/472 (22%), Positives = 154/472 (32%), Gaps = 38/472 (8%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 834  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 882

Query: 204  IPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 263
               E +   T+S++   AT+  S T +A  E +E      +   + + S    +   +S+
Sbjct: 883  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 939

Query: 264  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNG--TTAYEGNWNPEAH 321
            T S T  A   + +  + T  +   S    +  T +    V   G  TT      +    
Sbjct: 940  TGSETTTA---STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 996

Query: 322  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT 381
                  E          T+T     S TT  ++T  E    +        T  E S +TT
Sbjct: 997  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1056

Query: 382  GTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITL 438
             T A S  T+    G   TT S E S  T      S              + +S S  T 
Sbjct: 1057 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1116

Query: 439  QPTANPNTGLV-------EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS 491
              TA   T  V             G  + T   ++S++ + S  G E      T S  T+
Sbjct: 1117 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1176

Query: 492  SNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVT 544
             +             SE +TT  EG  +    T  S T           T++ +GS   T
Sbjct: 1177 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1236

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            A T G   S  + + S     F    GS TT  S +      +   G+ TT+
Sbjct: 1237 ACTTGSETSTPSSAGSETNTAF--IIGSETTIASTASLEPTATSLTGSETTT 1286



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 409 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 464

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 465 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 522

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 523 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 581

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 582 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 641

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 642 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 698

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 699 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 758

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 759 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 811

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 812 ETTKVSTASSKMTT 825



 Score = 33.1 bits (74), Expect = 0.90
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 44  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 103

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 104 SGT---TTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 159

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 160 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 216

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 217 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 256


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 104/472 (22%), Positives = 154/472 (32%), Gaps = 38/472 (8%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 263
               E +   T+S++   AT+  S T +A  E +E      +   + + S    +   +S+
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 264  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNG--TTAYEGNWNPEAH 321
            T S T  A   + +  + T  +   S    +  T +    V   G  TT      +    
Sbjct: 919  TGSETTTA---STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 322  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT 381
                  E          T+T     S TT  ++T  E    +        T  E S +TT
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 382  GTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITL 438
             T A S  T+    G   TT S E S  T      S              + +S S  T 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 439  QPTANPNTGLV-------EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS 491
              TA   T  V             G  + T   ++S++ + S  G E      T S  T+
Sbjct: 1096 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1155

Query: 492  SNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVT 544
             +             SE +TT  EG  +    T  S T           T++ +GS   T
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            A T G   S  + + S     F    GS TT  S +      +   G+ TT+
Sbjct: 1216 ACTTGSETSTPSSAGSETNTAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 104/472 (22%), Positives = 154/472 (32%), Gaps = 38/472 (8%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 263
               E +   T+S++   AT+  S T +A  E +E      +   + + S    +   +S+
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 264  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNG--TTAYEGNWNPEAH 321
            T S T  A   + +  + T  +   S    +  T +    V   G  TT      +    
Sbjct: 919  TGSETTTA---STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 322  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT 381
                  E          T+T     S TT  ++T  E    +        T  E S +TT
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 382  GTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITL 438
             T A S  T+    G   TT S E S  T      S              + +S S  T 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 439  QPTANPNTGLV-------EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS 491
              TA   T  V             G  + T   ++S++ + S  G E      T S  T+
Sbjct: 1096 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1155

Query: 492  SNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVT 544
             +             SE +TT  EG  +    T  S T           T++ +GS   T
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            A T G   S  + + S     F    GS TT  S +      +   G+ TT+
Sbjct: 1216 ACTTGSETSTPSSAGSETNTAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/491 (21%), Positives = 169/491 (34%), Gaps = 51/491 (10%)

Query: 131  SVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTS 190
            S T +     G  T++I   + T+    G   T       S  T   ++ GS +  +ST 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGS-ETTTTSTEGSEITTASIT-GSETTTASTE 738

Query: 191  GGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENE-----DERDR 245
            G       +T      E +   T  ++   A++TSS T  A    +E         E  +
Sbjct: 739  GSET----TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 246  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 305
              + S        +   +TI++T  +   T           S +  E    TTT  T+  
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET---TTTTSTEGS 851

Query: 306  RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 365
               T + EG+    A          E  ET  +T+    T +++TE + T      G+  
Sbjct: 852  ETTTASTEGSETTTAST--------ESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 366  HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 425
                 +  +  + STTG+   +A T       TT S E S  T      S  +    +  
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEG--SETTTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 426  RRMDMDSSHS-ITLQPTANPNTGLVED-----------------LDRTGPLSMTTQQSNS 467
                + +  S  T   TA   T  V                   +  TG  + T   + +
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021

Query: 468  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTK 525
            ++  TS EG E      TT T   S    V  TG       +EGS T     T     T 
Sbjct: 1022 ETTITSTEGSET-----TTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 526  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 585
             +      T + +GS   TA T G   + V   ++G + T   + GS  T  S +   + 
Sbjct: 1077 STADLETTTVSTSGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 586  GSQEGGANTTS 596
             +   G+  T+
Sbjct: 1135 TASTTGSEMTT 1145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 118/533 (22%), Positives = 177/533 (33%), Gaps = 61/533 (11%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGYIFYTFSTVHPIPDEDS 209
            G   T    I P        SS        GS + R+ST G       +TV     E +
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET----TTVSTTGSETT 354

Query: 210 PWITDSTDRIPATSTSSNTISAGWEPNE----ENEDERDRHLSFSGS-----GIDDDEDF 260
                 ++    ++T S T +A  E +E      E      +S +GS      I D E  
Sbjct: 355 TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETT 414

Query: 261 ISST-------ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE 313
            + T       +STT   F+ T  + + ++   + ++     +TTT  T+     T    
Sbjct: 415 TTCTEGSEMTAVSTT--VFETTTASTEGSEITIASTSDS---ETTTASTEGSETTTVTTA 469

Query: 314 GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTP 373
           G+    A+      E      T   T+T+    S TT  +    E    +          
Sbjct: 470 GSETKTAYTT--GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 374 KEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS-----SWTDFFNPISHPMGRGHQAGR 426
            E S +TT +   S  T+    G   TT S E S     S T          G G  A  
Sbjct: 528 TEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 427 RMDMDSSHSITLQP---TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDH 483
               +++   T      TA+           TG  + T   ++S++ + S EG E     
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 484 PTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGV 543
            T S  T  +    TG  R    +EGS T           T  S T    T +  GS G 
Sbjct: 648 TTDSETTMVS---TTGSERTITSTEGSET-----------TTVSATGSETTVSTEGS-GT 692

Query: 544 TAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
           T V++  S +    +   +  T    G   TT        +  S EG   TT+
Sbjct: 693 TTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 103/472 (21%), Positives = 154/472 (32%), Gaps = 38/472 (8%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 263
               E +   T+S++   AT+  S T +A  E +E      +   + + S    +   +S+
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 264  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNG--TTAYEGNWNPEAH 321
            T S T  A   + +  + T  +   S    +  T +    V   G  TT      +    
Sbjct: 919  TGSETTTA---STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTT 975

Query: 322  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT 381
                  E          T+T     S TT  ++T  E    +        T  E S +TT
Sbjct: 976  ASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTT 1035

Query: 382  GTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITL 438
             T A S  T+    G   TT S E S  T      S              + +S S  T 
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 439  QPTANPNTGLV-------EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS 491
              TA   T  V             G  + T   ++S++ + S  G E      T S  T+
Sbjct: 1096 ASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT 1155

Query: 492  SNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVT 544
             +             SE +TT  EG  +    T  S T           T++ +GS   T
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 545  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 596
            A T G   S  + + S     F    GS +T  S +      +   G+ TT+
Sbjct: 1216 ACTTGSETSTPSSAGSETNTAF--IIGSESTIASTASLEPTATSLTGSETTT 1265



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 90/434 (20%), Positives = 147/434 (33%), Gaps = 28/434 (6%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATSTSSNTISAGWEPNEE 238
           + GS +   ST+G       +TV     E +   T+ ++    ++T   T +A  E +E 
Sbjct: 388 TEGSEATTVSTTGSET----TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 239 NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVL-LQT 297
                    + + S    +   +++  S T  A+  T  ++  T  N       V  + +
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAY--TTGSETTTASNTGLETTTVFTIGS 501

Query: 298 TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 357
            T     + + TTA     +          E+     T   T+T+  T   TT  T+T+ 
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT-TSTEG 560

Query: 358 EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT---SHPMQGRTTPSPEDSSWTDFFNPI 414
            +            T   +   TT  + A + T   S      TT S  DS  T      
Sbjct: 561 SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 415 SHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTS 473
           S        +       +  S  T   T +  T +V     TG     T    S++ + S
Sbjct: 621 SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST---TGSERTITSTEGSETTTVS 677

Query: 474 HEGLEE----DKDHPTTSTLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKES 527
             G E     +    TT ++T S    V  TG       +EGS       T     T  +
Sbjct: 678 ATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 528 RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 587
                 T++  GS   +A T G   +    S +  + T     GS TT  S     + GS
Sbjct: 738 EGSETTTASTEGSETTSASTTGSETTTA--STTSSETTMASIMGSETTMAS-----TIGS 790

Query: 588 QEGGANTTSGPIRT 601
           +    +T S  + T
Sbjct: 791 ETTKVSTASSKMTT 804



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 377 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 435 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 495 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 553
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 554 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 595
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 70/313 (22%), Positives = 107/313 (34%), Gaps = 45/313 (14%)

Query: 302  TDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHST-STIQATPSSTTE-------ET 353
            ++V   G+  + G+ + +A       +H E E T H    T       TTE       +T
Sbjct: 1886 SEVHSGGSHTHSGHTHSQARS-----QHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQT 1940

Query: 354  ATQKEQWFGNRW--HEGYRQT--PKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTD 409
                 +  G R   H  Y  +  P   SH+ +G     A + +P  G +      ++   
Sbjct: 1941 IQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQ 2000

Query: 410  FFNPISHP-MGRGHQA-------GRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMT 461
              +   H   G G          GRR    S +S +   +   +T       + G     
Sbjct: 2001 TADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGE 2060

Query: 462  TQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHY 521
            +  S  +   T+H    +   H  +    S+ R   T GRR   HSE S + +    S  
Sbjct: 2061 SGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVS-- 2118

Query: 522  PHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESD 581
             HT    T           +G      G+S S    ++ G Q T H   G  T HG    
Sbjct: 2119 -HTHSGHT-----------YGQARSQHGESGS----AIHGRQGTIHGQTGDTTRHG--QS 2160

Query: 582  GHSHGSQEGGANT 594
            GH   +Q G   T
Sbjct: 2161 GHGQSTQTGSRTT 2173



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 72/300 (24%), Positives = 107/300 (35%), Gaps = 45/300 (15%)

Query: 330  HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 389
            H  +ET H  +      S + +  +TQ     G+R     R +  E+S S   +  +  H
Sbjct: 1233 HGRQETTHGQTINTTRHSQSGQGQSTQT----GSRVTRRRRSSQSENSDSEVHSKVSHRH 1288

Query: 390  TSH---------PMQGRTTPSPEDSSWTDFFNPISHPM---GRGHQAGRRMDMDSSHSIT 437
            + H         P  G T    + ++     +   H     G+  Q G R       S +
Sbjct: 1289 SEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHS 1348

Query: 438  LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQ---SFSTSHEGLE-------EDKDHPTTS 487
                +  ++G+     R      T  Q+ SQ   S ST HE  E       E   H  + 
Sbjct: 1349 DATDSEVHSGVSH---RPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSG 1405

Query: 488  TLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS-FGVTAV 546
               S+ R   T GRR   HSE S + +    SH P ++E       T  + GS  G +  
Sbjct: 1406 HGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQ------THGQAGSQHGESGS 1459

Query: 547  TVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSES-----DGHSHGS----QEGGANTTSG 597
            TV   +   +          H   G  T  GS +      GHS  S      GG++T SG
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSG 1519



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 66/255 (25%), Positives = 85/255 (33%), Gaps = 41/255 (16%)

Query: 378  HSTTGTAAASAHTSHPMQGRT---TPSPEDSSWTDFFNPISH------PMGRGH---QAG 425
            H  TG     AH+ H    +T   T     S  +++ +   H      P  RGH   QAG
Sbjct: 1771 HGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAG 1830

Query: 426  RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHP- 484
             +     S       T +  TG      ++G    T  QS S +      G  E  D   
Sbjct: 1831 SQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQST--QSGSSTTGRRRSGHSESSDSEV 1888

Query: 485  ------TTSTLTSSNRNDVTGGRRDPNHSEGSTTLLE-GYTSHYPHTKESRTFIPVTSAK 537
                  T S  T S      G      H    TT  + G T+ + H    +T I   S  
Sbjct: 1889 HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQT-IQTGSRT 1947

Query: 538  TGSFGVTAVTVGDSN--SNVNRSLSGDQDTFHPSGGSH-------------TTHGSESDG 582
            TG  G       DS   S V+ + SG     H   GSH             TTHG  +D 
Sbjct: 1948 TGRRGSGHSEYSDSEGPSGVSHTHSGHT---HGQAGSHYPESGSSVHERHGTTHGQTADT 2004

Query: 583  HSHGSQEGGANTTSG 597
              HG    G +T  G
Sbjct: 2005 TRHGHSGHGQSTQRG 2019



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 57/281 (20%), Positives = 97/281 (34%), Gaps = 19/281 (6%)

Query: 327  HEHHEE------EETPHSTSTI-QATP--SSTTEETATQKEQWFGNRWHEG--YRQTPKE 375
            HE HE       E T H  S   Q+T   S TT    +   +   +  H G  +R   +E
Sbjct: 1385 HERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQE 1444

Query: 376  DSHSTTGTA-AASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 434
             +H   G+    S  T H   G T     D++    ++            GRR    S  
Sbjct: 1445 QTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSES 1504

Query: 435  SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 494
            S +   +   +T       ++G     ++         +H    +   H  +    ++  
Sbjct: 1505 SDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQT 1564

Query: 495  NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS-FGVTAVTVGDSNS 553
               T GR+  +HSE + + +    SH PH++E       T  + GS       TV + + 
Sbjct: 1565 GSRTTGRQRTSHSESTDSEVHSGGSHRPHSREH------TYGQAGSQHEEPEFTVHERHG 1618

Query: 554  NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANT 594
              +  +       H   G  T  GS + G    S    +++
Sbjct: 1619 TTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDS 1659



 Score = 36.6 bits (83), Expect = 0.081
 Identities = 96/472 (20%), Positives = 155/472 (32%), Gaps = 86/472 (18%)

Query: 157  QKGEYRTNPEDIYPSNPTDDDVSSG------SSSERSSTSGGYIFYTFSTVHPIPDEDSP 210
            Q G   +  +    S+ TD +V SG      S  +  S +G     + STVH   +    
Sbjct: 1334 QTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYG 1393

Query: 211  WITDSTDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPR 270
               ++T               G   + ++     R     GSG  +  D      S    
Sbjct: 1394 QTGEATGH-------------GHSGHGQSTQRGSRTTGRRGSGHSESSD------SEVHS 1434

Query: 271  AFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTT-AYEGNWNPEAHPPLIHHEH 329
               H  Q+Q+ T       + E      +  T   R+GTT    G+    AH       +
Sbjct: 1435 GGSHRPQSQEQTHGQAGSQHGE------SGSTVHGRHGTTHGQTGDTTRHAH-------Y 1481

Query: 330  HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 389
            H  + T   +ST     S  +E + ++     G+  H G+        H  + +     H
Sbjct: 1482 HHGKSTQRGSSTTGRRGSGHSESSDSEVHSG-GSHTHSGHTHGQSGSQHGESESIIHDRH 1540

Query: 390  T-SHPMQGRTT----PSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANP 444
              +H   G TT       E ++ T                   +    SH    +P +  
Sbjct: 1541 RITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSH----RPHSRE 1596

Query: 445  NTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 504
            +T       + G      + +  +   T+H  + +   H  +    S+ R   T GR+  
Sbjct: 1597 HT-----YGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRS 1651

Query: 505  NHSEGSTTLLEGYTSHYPHT-----------KESRTFIP----VTSAKTGS--------F 541
            +HSE S + +    SH  HT            +S + +P     T  +TG          
Sbjct: 1652 SHSESSDSEVHSGVSH-THTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHH 1710

Query: 542  GVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHG---SQEG 590
            G+T  T   +        S   D+   SG SHT       GH+HG   SQ G
Sbjct: 1711 GLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHT-----HSGHTHGQARSQHG 1757



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 60/287 (20%), Positives = 93/287 (32%), Gaps = 19/287 (6%)

Query: 330  HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKED-----SHSTTGTA 384
            HE   T H  +      + +    +TQ+      R   G+ ++   +     SH+ +G  
Sbjct: 2066 HERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHT 2125

Query: 385  AASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPM---GRGHQAGRRMD--MDSSHSITLQ 439
               A + H   G      + +      +   H     G+  Q G R      SSHS +  
Sbjct: 2126 YGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSD 2185

Query: 440  PTANPNTGLVEDLDRTGPLSMTTQQSNSQSFS---TSHEGLEEDKDHPTTSTLTSSNRND 496
               +                    QS S       T+H    +   H       S+ R  
Sbjct: 2186 SEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGS 2245

Query: 497  VTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS--FGVTAVTVGDSNSN 554
             T GRR   HSE S + +  + SH  H+   +        + GS   G    T G +   
Sbjct: 2246 RTTGRRGSGHSESSDSEVHSWGSH-THSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDT 2304

Query: 555  VNRSLSG-DQDTFHPSGGSHTTH--GSESDGHSHGSQEGGANTTSGP 598
                 SG  Q T   S  S  +H     S+   HGS +   + + GP
Sbjct: 2305 TRHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGP 2351


>gi|38372931 brevican isoform 2 [Homo sapiens]
          Length = 671

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 82/375 (21%), Positives = 131/375 (34%), Gaps = 47/375 (12%)

Query: 48  EAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFI-EGHVVIPRIHPNSICAANNTGVYI 106
           EA   C+   + + T  Q+  A   G + C  G++ +G V  P + P+  C     GV  
Sbjct: 272 EARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKT 331

Query: 107 L---------TSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           L          +  S+++ YCF  SA P     +     N     +   +   +    +Q
Sbjct: 332 LFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQ 391

Query: 158 KGEYRTNPED---IYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITD 214
             +  T  E    IY S P  +D   GSS+             F T              
Sbjct: 392 LPQEATESESRGAIY-SIPIMEDGGGGSSTPEDPAEAPRTLLEFET-------------- 436

Query: 215 STDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFI--SSTISTTPRAF 272
               +P T  S     A  E  E+ EDE ++        ++D+  +   S   S  P A 
Sbjct: 437 -QSMVPPTGFSEEEGKA-LEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEAS 494

Query: 273 DHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEE 332
             T+            +  E L Q   R   V + G +      +  + PP +H    E 
Sbjct: 495 LPTEPA----------AQEESLSQAPARA--VLQPGASPLPDGESEASRPPRVHGPPTET 542

Query: 333 EETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSH 392
             TP   +   A+PS +T   A +  +  G     G  +   E++ S+ G  +    T  
Sbjct: 543 LPTPRERNL--ASPSPSTLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRA 600

Query: 393 PMQGRTTPSP-EDSS 406
           P   R   +P ED+S
Sbjct: 601 PEGTRELEAPSEDNS 615



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 6/89 (6%)

Query: 37  EKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVV-IPRIHPNS 95
           E + RY+ S + A + C    + + T  Q+  A   G+E C  G++    V  P   P  
Sbjct: 163 EGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPRE 222

Query: 96  ICAANNTGV-----YILTSNTSQYDTYCF 119
            C  +  G      Y +      YD YC+
Sbjct: 223 ACYGDMDGFPGVRNYGVVDPDDLYDVYCY 251


>gi|38372935 brevican isoform 1 [Homo sapiens]
          Length = 911

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 82/375 (21%), Positives = 131/375 (34%), Gaps = 47/375 (12%)

Query: 48  EAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFI-EGHVVIPRIHPNSICAANNTGVYI 106
           EA   C+   + + T  Q+  A   G + C  G++ +G V  P + P+  C     GV  
Sbjct: 272 EARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKT 331

Query: 107 L---------TSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           L          +  S+++ YCF  SA P     +     N     +   +   +    +Q
Sbjct: 332 LFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQ 391

Query: 158 KGEYRTNPED---IYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITD 214
             +  T  E    IY S P  +D   GSS+             F T              
Sbjct: 392 LPQEATESESRGAIY-SIPIMEDGGGGSSTPEDPAEAPRTLLEFET-------------- 436

Query: 215 STDRIPATSTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFI--SSTISTTPRAF 272
               +P T  S     A  E  E+ EDE ++        ++D+  +   S   S  P A 
Sbjct: 437 -QSMVPPTGFSEEEGKA-LEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEAS 494

Query: 273 DHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEE 332
             T+            +  E L Q   R   V + G +      +  + PP +H    E 
Sbjct: 495 LPTEPA----------AQEESLSQAPARA--VLQPGASPLPDGESEASRPPRVHGPPTET 542

Query: 333 EETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSH 392
             TP   +   A+PS +T   A +  +  G     G  +   E++ S+ G  +    T  
Sbjct: 543 LPTPRERNL--ASPSPSTLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRA 600

Query: 393 PMQGRTTPSP-EDSS 406
           P   R   +P ED+S
Sbjct: 601 PEGTRELEAPSEDNS 615



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 6/89 (6%)

Query: 37  EKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVV-IPRIHPNS 95
           E + RY+ S + A + C    + + T  Q+  A   G+E C  G++    V  P   P  
Sbjct: 163 EGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPRE 222

Query: 96  ICAANNTGV-----YILTSNTSQYDTYCF 119
            C  +  G      Y +      YD YC+
Sbjct: 223 ACYGDMDGFPGVRNYGVVDPDDLYDVYCY 251


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,764,327
Number of Sequences: 37866
Number of extensions: 1472674
Number of successful extensions: 4994
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 110
Number of HSP's that attempted gapping in prelim test: 4448
Number of HSP's gapped (non-prelim): 459
length of query: 699
length of database: 18,247,518
effective HSP length: 109
effective length of query: 590
effective length of database: 14,120,124
effective search space: 8330873160
effective search space used: 8330873160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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