Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 48255935

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48255935 CD44 antigen isoform 1 precursor [Homo sapiens]
         (742 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48255935 CD44 antigen isoform 1 precursor [Homo sapiens]          1540   0.0  
gi|48255937 CD44 antigen isoform 2 precursor [Homo sapiens]          1427   0.0  
gi|48255939 CD44 antigen isoform 3 precursor [Homo sapiens]           543   e-154
gi|48255941 CD44 antigen isoform 4 precursor [Homo sapiens]           468   e-131
gi|48255943 CD44 antigen isoform 5 precursor [Homo sapiens]           165   2e-40
gi|40549451 lymphatic vessel endothelial hyaluronan receptor 1 [...    77   8e-14
gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu...    64   7e-10
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    59   1e-08
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             57   5e-08
gi|167736355 mucin 4 isoform a [Homo sapiens]                          56   1e-07
gi|161019170 mucin 5AC [Homo sapiens]                                  55   3e-07
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       53   9e-07
gi|61743978 stabilin 1 precursor [Homo sapiens]                        52   2e-06
gi|60097902 filaggrin [Homo sapiens]                                   52   2e-06
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             50   8e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        50   8e-06
gi|91982772 mucin 17 [Homo sapiens]                                    50   8e-06
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    50   1e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    50   1e-05
gi|161016767 mucin 21 [Homo sapiens]                                   49   2e-05
gi|62122917 filaggrin family member 2 [Homo sapiens]                   47   6e-05

>gi|48255935 CD44 antigen isoform 1 precursor [Homo sapiens]
          Length = 742

 Score = 1540 bits (3986), Expect = 0.0
 Identities = 742/742 (100%), Positives = 742/742 (100%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE 240
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE 240

Query: 241 TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 300
           TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD
Sbjct: 241 TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 300

Query: 301 EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN 360
           EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN
Sbjct: 301 EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN 360

Query: 361 PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS 420
           PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS
Sbjct: 361 PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS 420

Query: 421 HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT 480
           HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT
Sbjct: 421 HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT 480

Query: 481 LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV 540
           LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV
Sbjct: 481 LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV 540

Query: 541 TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR 600
           TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR
Sbjct: 541 TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR 600

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL
Sbjct: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660

Query: 661 ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET 720
           ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET
Sbjct: 661 ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET 720

Query: 721 PDQFMTADETRNLQNVDMKIGV 742
           PDQFMTADETRNLQNVDMKIGV
Sbjct: 721 PDQFMTADETRNLQNVDMKIGV 742


>gi|48255937 CD44 antigen isoform 2 precursor [Homo sapiens]
          Length = 699

 Score = 1427 bits (3695), Expect = 0.0
 Identities = 698/742 (94%), Positives = 699/742 (94%), Gaps = 43/742 (5%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE 240
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT+                 
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATS----------------- 223

Query: 241 TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 300
                                     TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD
Sbjct: 224 --------------------------TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 257

Query: 301 EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN 360
           EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN
Sbjct: 258 EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN 317

Query: 361 PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS 420
           PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS
Sbjct: 318 PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS 377

Query: 421 HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT 480
           HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT
Sbjct: 378 HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT 437

Query: 481 LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV 540
           LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV
Sbjct: 438 LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV 497

Query: 541 TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR 600
           TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR
Sbjct: 498 TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR 557

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL
Sbjct: 558 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 617

Query: 661 ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET 720
           ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET
Sbjct: 618 ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET 677

Query: 721 PDQFMTADETRNLQNVDMKIGV 742
           PDQFMTADETRNLQNVDMKIGV
Sbjct: 678 PDQFMTADETRNLQNVDMKIGV 699


>gi|48255939 CD44 antigen isoform 3 precursor [Homo sapiens]
          Length = 493

 Score =  543 bits (1400), Expect = e-154
 Identities = 283/326 (86%), Positives = 289/326 (88%), Gaps = 18/326 (5%)

Query: 418 EDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSW-TDFFNPISHPMGRGHQAGRRMDMDSS 476
           E S ++ G    +  T HP+        EDS W TD  + I              +MDSS
Sbjct: 185 ERSSTSGGYIFYTFSTVHPIPD------EDSPWITDSTDRIP-----------ATNMDSS 227

Query: 477 HSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSN 536
           HSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSN
Sbjct: 228 HSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSN 287

Query: 537 RNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNS 596
           RNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNS
Sbjct: 288 RNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNS 347

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILAS 656
           NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILAS
Sbjct: 348 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILAS 407

Query: 657 LLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKE 716
           LLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKE
Sbjct: 408 LLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKE 467

Query: 717 SSETPDQFMTADETRNLQNVDMKIGV 742
           SSETPDQFMTADETRNLQNVDMKIGV
Sbjct: 468 SSETPDQFMTADETRNLQNVDMKIGV 493



 Score =  476 bits (1226), Expect = e-134
 Identities = 269/449 (59%), Positives = 296/449 (65%), Gaps = 61/449 (13%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMST-SATATETATKRQ 239
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT + S+ S T   TA    
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATNMDSSHSITLQPTANPN- 239

Query: 240 ETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDD 299
                 + L    +    L  TTQ + + S                     S S  G+++
Sbjct: 240 ------TGLVEDLDRTGPLSMTTQQSNSQS--------------------FSTSHEGLEE 273

Query: 300 DEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNW 359
           D+D  +++  T+    D T   +D     P+HS                   TT  EG  
Sbjct: 274 DKDHPTTSTLTSSNRNDVTGGRRD-----PNHS----------------EGSTTLLEGYT 312

Query: 360 NPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQT--PK 417
           +        H+ H +E  T    ++ +      T  T         NR   G + T  P 
Sbjct: 313 S--------HYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNV-NRSLSGDQDTFHPS 363

Query: 418 EDSHSTTGTAA-ASAHTSHPMQGRTTPSP 445
             SH+T G+ +   +H S      TT  P
Sbjct: 364 GGSHTTHGSESDGHSHGSQEGGANTTSGP 392


>gi|48255941 CD44 antigen isoform 4 precursor [Homo sapiens]
          Length = 361

 Score =  468 bits (1203), Expect = e-131
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
           MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1   MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120
           PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN
Sbjct: 61  PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN 120

Query: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180
           ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS
Sbjct: 121 ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS 180

Query: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
           GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT
Sbjct: 181 GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222



 Score =  279 bits (714), Expect = 6e-75
 Identities = 138/138 (100%), Positives = 138/138 (100%)

Query: 605 DQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALIL 664
           DQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALIL
Sbjct: 224 DQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALIL 283

Query: 665 AVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQF 724
           AVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQF
Sbjct: 284 AVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQF 343

Query: 725 MTADETRNLQNVDMKIGV 742
           MTADETRNLQNVDMKIGV
Sbjct: 344 MTADETRNLQNVDMKIGV 361


>gi|48255943 CD44 antigen isoform 5 precursor [Homo sapiens]
          Length = 139

 Score =  165 bits (417), Expect = 2e-40
 Identities = 77/77 (100%), Positives = 77/77 (100%)

Query: 1  MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60
          MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL
Sbjct: 1  MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL 60

Query: 61 PTMAQMEKALSIGFETC 77
          PTMAQMEKALSIGFETC
Sbjct: 61 PTMAQMEKALSIGFETC 77


>gi|40549451 lymphatic vessel endothelial hyaluronan receptor 1
           [Homo sapiens]
          Length = 322

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 41/115 (35%), Positives = 59/115 (51%), Gaps = 2/115 (1%)

Query: 17  LSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFET 76
           L   ++ + ++CR  G+  V K     ++ TEA + C+    +L    Q+E AL   FET
Sbjct: 25  LRAEELSIQVSCRIMGITLVSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFET 84

Query: 77  CRYGFI-EGHVVIPRIHPNSICAANNTGVYILTSNTS-QYDTYCFNASAPPEEDC 129
           C YG++ +G VVI RI PN  C  N  GV I     S Q+  YC+N+S      C
Sbjct: 85  CSYGWVGDGFVVISRISPNPKCGKNGVGVLIWKVPVSRQFAAYCYNSSDTWTNSC 139


>gi|26051243 tumor necrosis factor, alpha-induced protein 6
           precursor [Homo sapiens]
          Length = 277

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 9/120 (7%)

Query: 29  RFAGVFHVE-KNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFI-EGHV 86
           R AGV+H E ++G+Y ++  EA  +C+     L T  Q+E A  IGF  C  G++ +G V
Sbjct: 33  RAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGRV 92

Query: 87  VIPRIHPNSICAANNTGVY---ILTSNTSQYDTYCFNASAPPEEDCTSV-TDLPNAFDGP 142
             P + P   C    TG+    I  + + ++D YC+N   P  ++C  V TD    F  P
Sbjct: 93  GYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYN---PHAKECGGVFTDPKQIFKSP 149


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 82/478 (17%), Positives = 184/478 (38%), Gaps = 8/478 (1%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            +N  D   S+ + D  SS  SS  S +S        S      D      +DS+D   + 
Sbjct: 663  SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722

Query: 223  TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
            +  S S+ +++++     +    S     S+S N    ++  + +S+++ S+    + ++
Sbjct: 723  SSDSDSSNSSDSSDSSNSSDSSDS-----SDSSNS-SDSSDSSDSSNSSDSSDSSDSSDS 776

Query: 283  EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTT 342
             D  +   S   S   D  D  +S+ S+       +  + D    N S S+       ++
Sbjct: 777  SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836

Query: 343  RMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQ 402
              +D   + + + +G+ +  ++     +     + +  S S+  +  S + E + +    
Sbjct: 837  NSSD-SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895

Query: 403  WFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMG 462
               N        +      S +  ++ S+ +S+      +    +SS +   +  S+   
Sbjct: 896  DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955

Query: 463  RGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEE 522
              + +      DSS S +   + + N+    D   +   S ++  SNS   S S +  + 
Sbjct: 956  SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015

Query: 523  DKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTG 582
                 ++++  SSN +D +      + S+ S +     +S+   + +S      + +   
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075

Query: 583  SFGVTAVTVGDSNSNVNRSLSGD-QDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            S    +    DS+ + N S S D  D+   S  S ++  S+S   S+ S    ++ +S
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 77/478 (16%), Positives = 175/478 (36%), Gaps = 31/478 (6%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            ++  D   SN +D D S+ S S  SS S                 DS   +DS+D   ++
Sbjct: 713  SDSSDSSNSNSSDSDSSNSSDSSDSSNSSD----------SSDSSDSSNSSDSSDSSDSS 762

Query: 223  TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
                +S ++  + +               S   N    ++  + +S+++ S+    + ++
Sbjct: 763  NSSDSSDSSDSSDSSDSSN----------SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812

Query: 283  EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTT 342
             D  D   S S    +  +   SS  S +  + D +  +   +      SN      ++ 
Sbjct: 813  SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872

Query: 343  RMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQ 402
                 D + ++    + N        +    +  ++ +S+ +  ++ SS + E++   + 
Sbjct: 873  SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD- 931

Query: 403  WFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMG 462
                  +     +      S +  ++ S+ +S+      +    DS+ +D  +  S+   
Sbjct: 932  ------NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS-SNSSD 984

Query: 463  RGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEE 522
                +      DSS S     +++ +     D   +   S ++  SNS   S S +  + 
Sbjct: 985  SSDSSDSSDSSDSSDSSNSSDSSDSSDS--SDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 523  DKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTG 582
                 ++ +  SSN +D +      + S+ S +     +S    + +S      + +   
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102

Query: 583  SFGVTAVTVGDSNSNVNRSLSGD-QDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            S    +    DS+ + + S S D  D+   S  S +++ S+S   S  S    ++ +S
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 71/473 (15%), Positives = 177/473 (37%), Gaps = 12/473 (2%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            +N  D   S+ + D   S  SS+ S +       + ++       DS   +DS+D   + 
Sbjct: 827  SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886

Query: 223  TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
               ++S ++  + +   ++ D  S     S   ++   +++ + +S N+ S+    + ++
Sbjct: 887  ESSNSSDSSDSSNSSDSDSSD--SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 283  EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTT 342
             D  D   S   S   D  +   S+ S +  + D +  +      + S S+       ++
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004

Query: 343  RMTDVD-----RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETA 397
              +D        N + +   + +  +       +  +  ++  S+ +  ++ SS + +++
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064

Query: 398  TQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPI 457
               +    +   +    +   DS  ++ ++ +S  +       ++ S + S  +D  N  
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124

Query: 458  SHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSH 517
                             S  S + + + + ++    D   +   S ++  S+S + S S 
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184

Query: 518  EGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVT 577
            +  +      ++ +  SS+ +D +      + S+ S +     +S    + +S      +
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244

Query: 578  SAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 630
             +   S    +    DS S+ N     D+       G+   +GS+SD  S GS
Sbjct: 1245 DSSNSSDSSDSSDSSDSTSDSN-----DESDSQSKSGNGNNNGSDSDSDSEGS 1292



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 62/390 (15%), Positives = 152/390 (38%), Gaps = 20/390 (5%)

Query: 265 AGTSSNTISAGWEP---NEENEDERDRHLSFSGSGIDD---DEDFISSTISTTPRAFDHT 318
           + T S++ S G++    ++++    D + S   +G DD   + D  SS+        D +
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDES 498

Query: 319 KQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEET 378
           K N + +    +  +       T   +D + NG    + N   ++          +  ++
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNN-SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557

Query: 379 PHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQ 438
            +S+ +  ++ S +++  ++       +   +    +   DS +++ ++ +S  +     
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS-SDSDSSDSSNSSDSSDSSDSSDSSDS 616

Query: 439 GRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTAN----------PN 488
             ++ S  DSS ++  +  S        +      D+S S     ++N           +
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676

Query: 489 TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPN 548
           +    D   +   S ++  SNS   S S +  + D    + S+ ++S+ +D +      +
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 549 HSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDT 608
            S  S +     +S+   + +S       S+ +     ++ +   SNS+ +   S   D+
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSD--SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794

Query: 609 FHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
              S  S +++ S+S   S  S    +N++
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 66/388 (17%), Positives = 145/388 (37%), Gaps = 23/388 (5%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            +N  D   S+ + D   S +SS+ S++S        S  +     DS   +DS+D   + 
Sbjct: 933  SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS- 991

Query: 223  TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
               S S+ +++++     +    S     S   ++   ++  + +S ++ S+    + ++
Sbjct: 992  ---SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS 1048

Query: 283  EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTT 342
             D  D   S   S   D  D  SS  S +  + D ++ +      N S S+       ++
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106

Query: 343  RMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQ 402
              +D   +  ++   N + ++       +  +   +  S+ + +++ SS + +++   + 
Sbjct: 1107 DSSDSSDSSDSSDSSN-SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165

Query: 403  WFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMG 462
               +   +    +   DS S +  ++ S+ +S       +    DSS +   +  S    
Sbjct: 1166 SDSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224

Query: 463  RGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEE 522
                +      DSS S     ++N               S  +  S+  S STS    E 
Sbjct: 1225 SSDSSDSNESSDSSDSSDSSDSSN---------------SSDSSDSSDSSDSTSDSNDES 1269

Query: 523  DKDHPTTSTLTSSNRNDVTGGRRDPNHS 550
            D    + +   + + +D      D NHS
Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 95/409 (23%), Positives = 150/409 (36%), Gaps = 53/409 (12%)

Query: 260 TTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTK 319
           +TT  + T+    SA    +   E+    H S   +      D  +++  +      H+ 
Sbjct: 16  STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 75

Query: 320 QNQDWTQWNPSHSNPEVLL-QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEE 376
           Q+   T   P+ S   VLL ++TT         TTA  G+      P L       H   
Sbjct: 76  QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT---PGLSEKSTTFHSSP 132

Query: 377 ETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ---TPKEDSHSTTGTAA----- 428
            +P +T +  +T SS   E +T      G+     +     TP    HSTT  ++     
Sbjct: 133 RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 192

Query: 429 -----ASAHTSHPMQGRTTPSPEDSSWTDFFNPISHP-MGRGHQAGRRMDMDSSHSITLQ 482
                AS  TS P Q  TT      S     +P S   +  G ++        S   TL 
Sbjct: 193 TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 252

Query: 483 PTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED----KDHPTTSTLTSSNRN 538
           P +  ++G+VE   R    + + + + S + STS  GL+ +    + HP ++  T S  +
Sbjct: 253 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPS 311

Query: 539 DVTGGRRDP---NHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSN 595
             T    +    + S GST      T+H+P                     ++ T G S 
Sbjct: 312 TATAPVEESTTYHRSPGSTP-----TTHFP--------------------ASSTTSGHSE 346

Query: 596 SNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 644
            +     S D     PS    TT G   +  +  SQ G  +TT+ P  T
Sbjct: 347 KSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDST 395



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 70/312 (22%), Positives = 110/312 (35%), Gaps = 46/312 (14%)

Query: 374 EEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT 433
           EE  T HS++T   T SS    T+   E+        G   T      STT   +  +  
Sbjct: 14  EESTTSHSSTT--HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 71

Query: 434 SHPMQ------------------GRTTPSP--EDSSWTDFFNPISHPMGRGHQAGRRMDM 473
           SH  Q                  G +T SP    S  T      +   G   ++      
Sbjct: 72  SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 131

Query: 474 DSSHSITLQPTANPNTGLVED----------LDRTGPLSMTTQQSNSQSFSTSHE--GLE 521
             S + TL P +  ++G+ E+             T     TT    S+  +TSH   G  
Sbjct: 132 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 191

Query: 522 EDKDHPTTSTLTSSNRNDVTG----GRRDPNHSEGSTTLLE-GYTSHYPHTKESRTFIPV 576
           +    P ++T +  ++   T     G  D   S GSTT L  G  S   H+    T   +
Sbjct: 192 DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 251

Query: 577 TSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGAN 636
               T S G+      ++++ V+ S    + T  P+  S T+ G + +  +  +     +
Sbjct: 252 FPDSTTSSGIV-----EASTRVHSSTGSPRTTLSPA--SSTSPGLQGESTAFQTHPASTH 304

Query: 637 TTSGPIRTPQIP 648
           TT  P  T   P
Sbjct: 305 TTPSPPSTATAP 316



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 100/478 (20%), Positives = 159/478 (33%), Gaps = 95/478 (19%)

Query: 102 TGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEY 161
           TG  +L + ++       + ++P        T LP    G  T   ++   T +      
Sbjct: 79  TGTIVLPARSTTSVLLGESTTSPISSGSMETTALP----GSTTTPGLSEKSTTF--HSSP 132

Query: 162 RTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIF-YTFSTV------HPIPDEDSPWITD 214
           R+    + P++ T   VS  S++  S     +   +  ST       H      SP  TD
Sbjct: 133 RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 192

Query: 215 STDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISA 274
           +T  +PA+T  +TS  + E+ T                       T T ++  S+  +S 
Sbjct: 193 TT-LLPAST--TTSGPSQESTTSHSSPGS----------------TDTALSPGSTTALSF 233

Query: 275 GWEPNEENEDERDRHL-----SFSGSGIDDDEDFISSTI-----------STTP------ 312
           G E    +      H      S + SGI +    + S+            ST+P      
Sbjct: 234 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 293

Query: 313 RAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEH 372
            AF     +   T   PS +   V  ++TT         TT +  +     H       H
Sbjct: 294 TAFQTHPASTHTTPSPPSTATAPVE-ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH 352

Query: 373 HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 432
              + +  + S+  +T S  +EE++T   Q        G   T      +TT   +    
Sbjct: 353 SSPDASGTTPSSAHSTTSGVSEESSTSHSQ-------PGSTHTTAFPDSTTTSGLSQEPT 405

Query: 433 TSHPMQGR------TTPSP-----------------EDSSWTDFFNPISHPMGRGHQAGR 469
           TSH  QG       TTPSP                   S+ T  F+  S  +GR  ++  
Sbjct: 406 TSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT 465

Query: 470 RMDMDSSHSITLQPTANPNTGLVE----------DLDRTGPLSMTTQQSNSQSFSTSH 517
                 S   T  P +    GL E            D T   + TT    S+  +TSH
Sbjct: 466 VHSSPGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 523


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 100/461 (21%), Positives = 163/461 (35%), Gaps = 69/461 (14%)

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           TL  T+   +  ++K   TW   S   LPS S       T++   + +T +AG  P   +
Sbjct: 481 TLHETTTWPSSFSSKGHTTW---SQTELPSTSTG---AATRLVTGNPSTGTAGTIPRVPS 534

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQW----------NPSHS 332
           +         S  G   +    SS  +T P+      Q Q WTQ           +PS+S
Sbjct: 535 K--------VSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQ-WTQETGTTGEALLSSPSYS 585

Query: 333 NPEVLLQTTTRMTD--VDR------------NGTTAYEGNWNPEAHPPLIHHEHHEEEET 378
             +++   T+  +   +DR            N +T +  + +P+  P +    H +  +T
Sbjct: 586 VTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQT 645

Query: 379 PHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQ 438
              + T ++    T  +T T     F    H      P++    +  T  A A T     
Sbjct: 646 TQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTG---D 702

Query: 439 GRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMD----MDSSHSITLQPTANPNTGLVED 494
           G TT +P  +       P SH    G   G  +     +  ++S+   P   P       
Sbjct: 703 GHTTQAPTTALQAA---PSSHDATLGPSGGTSLSKTGALTLANSVVSTP-GGPEGQWTSA 758

Query: 495 LDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT---------TSTLTSSNRNDVTGGRR 545
              T P +        Q+ ST   G  +  +  +         T+T +SS  +  T    
Sbjct: 759 SASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGS 818

Query: 546 DPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGD 605
           +   + G TT      S   HT +S T +   SA   S G   V+ G ++S V       
Sbjct: 819 EGISTSGETTRFSSNPSRDSHTTQSTTELLSASA---SHGAIPVSTGMASSIV------- 868

Query: 606 QDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQ 646
             TFHP+    +T G  +   S  S       T+   R  Q
Sbjct: 869 PGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQ 909



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 67/289 (23%), Positives = 104/289 (35%), Gaps = 48/289 (16%)

Query: 378  TPHSTST-IQATPSSTTEETA---TQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT 433
            T H+T   +  TPS++T +T             R       T    + +   T+     T
Sbjct: 2507 TGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDT 2566

Query: 434  SHPMQGRTTPSP---EDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTG 490
            S    G  TP P     S+ T    P+  P+   + A       S+   T  P  + ++ 
Sbjct: 2567 SAASTGHATPLPVTSTSSASTGDTTPL--PVTDTYSA-------STGQATPLPVTDTSSA 2617

Query: 491  LVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHS 550
               D   T PL +T    ++ S ST H            + L  +N + V+ G   P H 
Sbjct: 2618 STGD---TTPLPVT----DTSSASTGH-----------ATPLPVTNTSSVSTGHATPLHV 2659

Query: 551  EGSTTLLEGYTSHYPHTKES------RTFIPVTSAK---TGSFGVTAVTVGDSNSNVNRS 601
               ++   G+T+  P T  S       T +PVT A    TG      VT+  S S+ + +
Sbjct: 2660 TSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTT 2719

Query: 602  L-----SGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTP 645
                  +    T H +    T   S S GH+       A++ S    TP
Sbjct: 2720 PLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP 2768


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 98/477 (20%), Positives = 166/477 (34%), Gaps = 65/477 (13%)

Query: 122  SAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRY--VQKGEYRTNPEDIYPSNPTDDDVS 179
            +APP +  TS    P A     T +   R  T    +     ++    + P  P+    +
Sbjct: 4748 TAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPI-PSSTLGT 4806

Query: 180  SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQ 239
            +G+  E+++T       T ST+HP    ++   T +     ATT  +TS+T+T ++T   
Sbjct: 4807 TGTLPEQTTTPVA----TMSTIHPSSTPETTH-TSTVLTTKATTTRATSSTSTPSSTPGT 4861

Query: 240  ETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDD 299
                  +W+     +       T    T S+T    W   E                   
Sbjct: 4862 ------TWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTA-------------- 4901

Query: 300  DEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNW 359
                 ++T ST   A   +     W    PS +   V + T +  T       TA   + 
Sbjct: 4902 -----TTTASTGSTATPSSTPGTTWILTEPS-TTATVTVPTGSTAT-ASSTQATAGTPHV 4954

Query: 360  NPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQ----KEQWFGNRWHEGYRQT 415
            +  A  P +         +P + + + A  S+ T  TAT          G  W     QT
Sbjct: 4955 STTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR-LSQT 5013

Query: 416  PKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDS 475
                +  +T T +++  T H     T  +    +      P S P G  H    ++   +
Sbjct: 5014 TTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTP-GTAHTT--KVPTTT 5070

Query: 476  SHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSS 535
            +   T  P+++P T L      T P+S         + ST H     +  H +T   T++
Sbjct: 5071 TTGFTATPSSSPGTALTPPT--TTPMS---------TMSTIHTSSTPETTHTSTVLTTTA 5119

Query: 536  NRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVG 592
                 T     P+ + G+T +L   T+              T+A TGS    + T G
Sbjct: 5120 TMTRATNSTATPSSTLGTTRILTELTT-----------TATTTAATGSTATLSSTPG 5165



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 68/302 (22%), Positives = 105/302 (34%), Gaps = 44/302 (14%)

Query: 381  STSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR 440
            +T+T   +  ST   ++T    W           T    S +T  +  A+A T H     
Sbjct: 4226 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA 4285

Query: 441  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGP 500
            TTP+   S  T F +P           G    + +  S    PTA   T +      T  
Sbjct: 4286 TTPTVTSSKATPFSSP-----------GTATALPALRSTATTPTATSFTAIPSSSLGTTW 4334

Query: 501  LSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS------- 553
              ++   + + + ST+      +  H +T   T++     TG    P+ + G+       
Sbjct: 4335 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVP 4394

Query: 554  TTLLEGYT---SHYPHTKE------SRTFIPVTSAKT-------GSFGVTAVTVGDSNSN 597
            TT   G+T   S  P T        S T  P TS  T       G+     V    + + 
Sbjct: 4395 TTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTV 4454

Query: 598  VNRSLSGDQDTFHPSGGSH---------TTHG-SESDGHSHGSQEGGANTTSGPIRTPQI 647
               S++    +   SG +H         TTHG S S    H  +    + TSG + T  I
Sbjct: 4455 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 4514

Query: 648  PE 649
             E
Sbjct: 4515 TE 4516



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 67/302 (22%), Positives = 104/302 (34%), Gaps = 44/302 (14%)

Query: 381  STSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR 440
            +T+T   +  ST   ++T    W           T    S +T  +  A+A T H     
Sbjct: 3079 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA 3138

Query: 441  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGP 500
            TTP+   S  T F +P           G    + +  S    PTA   T +      T  
Sbjct: 3139 TTPTVTSSKATPFSSP-----------GTATALPALRSTATTPTATSFTAIPSSSLGTTW 3187

Query: 501  LSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS------- 553
              ++   + + + ST+      +  H +T   T++     TG    P+ + G+       
Sbjct: 3188 TRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVL 3247

Query: 554  TTLLEGYT---SHYPHTKE------SRTFIPVTSAKT-------GSFGVTAVTVGDSNSN 597
            TT   G+T   S  P T        S T  P T   T       G+     V    + + 
Sbjct: 3248 TTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTV 3307

Query: 598  VNRSLSGDQDTFHPSGGSH---------TTHG-SESDGHSHGSQEGGANTTSGPIRTPQI 647
               S++    +   SG +H         TTHG S S    H  +    + TSG + T  I
Sbjct: 3308 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 3367

Query: 648  PE 649
             E
Sbjct: 3368 TE 3369



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 112/532 (21%), Positives = 172/532 (32%), Gaps = 114/532 (21%)

Query: 100  NNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPI--------TITIVNRD 151
            + TG + +  N +     C + S  P    TS T  P++  G          T T     
Sbjct: 2554 DQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTAST 2613

Query: 152  GTRYVQKGEYRTNPED-IYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSP 210
            G+        RT P   +  +  T   V+S  ++  SS           +    P   S 
Sbjct: 2614 GSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS- 2672

Query: 211  WITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSN 270
             +T        TT    S T T TAT    T         PS +    HT+T +  T++ 
Sbjct: 2673 -VTPIPSSSLGTTWTRLSQTTTPTATMSTAT---------PSSTPETAHTSTVLTATATT 2722

Query: 271  TISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPS 330
            T + G               S +           +   +TT   F  T  +   T     
Sbjct: 2723 TGATG---------------SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA---- 2763

Query: 331  HSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPS 390
               P V + TTT  T   R  T        P + P   H            T+T+  T  
Sbjct: 2764 -LTPPVWISTTT--TPTTRGSTV------TPSSIPGTTH------------TATVLTT-- 2800

Query: 391  STTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSW 450
             TT   AT            G   TP   S  T+GT     HT                 
Sbjct: 2801 -TTTTVAT------------GSMATP-SSSTQTSGT----THTP---------------- 2826

Query: 451  TDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNS 510
                 P+ + M   H  GR +   S H++    T +  +G++     T P ++T+    +
Sbjct: 2827 -----PVPNTMATTH--GRSLPPSSPHTVRTAWT-SATSGILGTTHITEPSTVTSHTLAA 2878

Query: 511  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKES 570
             + +T H        HP++ T  S      + G   P H+  ++      T   P    +
Sbjct: 2879 TTGTTQHSTPALSSPHPSSRTTES----PPSPGTTTPGHTTATSRTTATAT---PSKTRT 2931

Query: 571  RTFIPVTSAKTGSFGVTAVTVG-DSNSNVNRSLSGDQDTFHPSGGSHTTHGS 621
             T +P  S+ T +   T VT+G +     +  L        PSGG   T+ +
Sbjct: 2932 STLLP--SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSN 2981



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 82/389 (21%), Positives = 124/389 (31%), Gaps = 75/389 (19%)

Query: 117  YCFNASAPPEEDCTSVTDLPNAFDGPI--------TITIVNRDGTRYVQKGEYRTNPEDI 168
            +C N    P    TS T +P++  G          T T     G+         T     
Sbjct: 3045 FCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILT 3104

Query: 169  YPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDS----------TDR 218
             PS      V +GS++  SST       T  T H      +P +T S             
Sbjct: 3105 EPSTTATVTVPTGSTATASSTQA-----TAGTPHVSTTATTPTVTSSKATPFSSPGTATA 3159

Query: 219  IPATTLMSTSATATE----TATKRQETWDWFSWLFLP---------SESKNHLHTTTQMA 265
            +PA    +T+ TAT      ++    TW   S    P         S +   +HT+T + 
Sbjct: 3160 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 3219

Query: 266  GTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWT 325
             T++ T + G               S +           +  ++TT   F  T  +   T
Sbjct: 3220 TTATTTGATG---------------SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGT 3264

Query: 326  QWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTI 385
                + + P  +  TTT  T     G+T       P + P   H        T    +  
Sbjct: 3265 ----ARTLPVWISTTTTPTT----RGSTV-----TPSSIPGTTHTPTVLTTTTTTVATGS 3311

Query: 386  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASA--------HTSHPM 437
             ATPSS+T+ + T       N     + ++    S  T  TA  SA        H + P 
Sbjct: 3312 MATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPS 3371

Query: 438  QGRTTPSPEDSSWTDFFNPI---SHPMGR 463
             G +      +  T    P     HP  R
Sbjct: 3372 TGTSHTPAATTGTTQHSTPALSSPHPSSR 3400



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 118/556 (21%), Positives = 188/556 (33%), Gaps = 129/556 (23%)

Query: 91   IHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFD-----GPITI 145
            IHP+S     +T   + T  T+   T   +  +        +T+L  A       GP T 
Sbjct: 3677 IHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGP-TA 3735

Query: 146  TIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGG-----YIFYTFST 200
            T  +  GT ++             PS      V +GS++  SST         +  T +T
Sbjct: 3736 TPSSTPGTTWILTE----------PSTTATVTVPTGSTATASSTRATAGTLKVLTSTATT 3785

Query: 201  VHPIPDEDSPWITDSTD------RIPATTLMSTSATATETA------TKRQETWDWFSWL 248
               I    +P  +  T       R  ATT  +TS TA  ++      T+  +T    + +
Sbjct: 3786 PTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATM 3845

Query: 249  FL--PSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 306
                PS +   +HT+T +  T++ T + G               S +           + 
Sbjct: 3846 STATPSSTPETVHTSTVLTTTTTTTRATG---------------SVATPSSTPGTAHTTK 3890

Query: 307  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPP 366
              +TT   F  T  +   T        P V + TTT  T   R  T        P + P 
Sbjct: 3891 VPTTTTTGFTATPSSSPGTA-----LTPPVWISTTT--TPTTRGSTV------TPSSIPG 3937

Query: 367  LIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGT 426
              H            T+T+  T   TT   AT            G   TP   S  T+GT
Sbjct: 3938 TTH------------TATVLTT---TTTTVAT------------GSMATP-SSSTQTSGT 3969

Query: 427  AAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTAN 486
                          T P P  ++ T                GR +   S H++    T +
Sbjct: 3970 T------------HTPPVPNTTATTH---------------GRSLPPSSPHTVRTAWT-S 4001

Query: 487  PNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRD 546
              +G++     T P ++T+    + + +T H        HP++ T  S      + G   
Sbjct: 4002 ATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTES----PPSPGTTT 4057

Query: 547  PNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVG-DSNSNVNRSLSGD 605
            P H+ G++      T   P    + T +P  S+ T +   T VT G +     +  L   
Sbjct: 4058 PGHTRGTSRTTATAT---PSKTRTSTLLP--SSPTSAPITTVVTTGCEPQCAWSEWLDYS 4112

Query: 606  QDTFHPSGGSHTTHGS 621
                 PSGG   T+ +
Sbjct: 4113 YPMPGPSGGDFDTYSN 4128



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 76/357 (21%), Positives = 124/357 (34%), Gaps = 56/357 (15%)

Query: 336  VLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLI----------HHEHHEEEETPHSTSTI 385
            +L + TT  T     G+TA   +    A PP +                   +P + +T+
Sbjct: 4722 ILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTL 4781

Query: 386  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGT-----AAASAHTSHPMQGR 440
                S+ T+ TAT       +    G   T  E + +   T      +++  T+H     
Sbjct: 4782 PVLTSTATKSTATSVTPIPSSTL--GTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVL 4839

Query: 441  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNT--GLVEDLDRT 498
            TT +    + +    P S P          +   ++ +    PTA P++  G    L   
Sbjct: 4840 TTKATTTRATSSTSTPSSTPGTTWILT--ELTTAATTTAATGPTATPSSTPGTTWILTEL 4897

Query: 499  GPLSMTTQQSNSQSFSTSHEG----LEEDKDH-----PTTSTLTSSNRN----------- 538
               + TT  + S +  +S  G    L E         PT ST T+S+             
Sbjct: 4898 TTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTT 4957

Query: 539  ----DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT----AVT 590
                 VT  +  P+ S G+ T L    S    T  + T    T+  + S G T    + T
Sbjct: 4958 ATTPTVTSSKATPSSSPGTATALPALRS----TATTPTATSFTAIPSSSLGTTWTRLSQT 5013

Query: 591  VGDSNSNVNRSLSGDQDTFHPS---GGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 644
               + +    + S   +T H S     + TT G+     +  S  G A+TT  P  T
Sbjct: 5014 TTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 5070



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 73/348 (20%), Positives = 119/348 (34%), Gaps = 66/348 (18%)

Query: 336  VLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLI----------HHEHHEEEETPHSTSTI 385
            +L + TT  T     G+TA   +    A PP +                   +P + +T+
Sbjct: 3575 ILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTL 3634

Query: 386  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSP 445
                S+ T+ TAT             +   P   +  TTGT      T+ PM   +T  P
Sbjct: 3635 PVLTSTATKSTAT------------SFTPIP-SFTLGTTGT--LPEQTTTPMATMSTIHP 3679

Query: 446  EDSSWTDFFNPISHPMGRGHQAGRRMDMDSS----------------HSITLQPTANPN- 488
              +  T   + +        +A   M   SS                 +    PTA P+ 
Sbjct: 3680 SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSS 3739

Query: 489  ----TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS-SNRNDVTGG 543
                T ++ +   T  +++ T  + + S + +  G        T   LTS +    V   
Sbjct: 3740 TPGTTWILTEPSTTATVTVPTGSTATASSTRATAG--------TLKVLTSTATTPTVISS 3791

Query: 544  RRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT----AVTVGDSNSNVN 599
            R  P+ S G+ T L    S    T  + T   VT+  + S G      + T   + +   
Sbjct: 3792 RATPSSSPGTATALPALRS----TATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMST 3847

Query: 600  RSLSGDQDTFHPS---GGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 644
             + S   +T H S     + TT  +     +  S  G A+TT  P  T
Sbjct: 3848 ATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTT 3895


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 111/534 (20%), Positives = 177/534 (33%), Gaps = 63/534 (11%)

Query: 100  NNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPI--------TITIVNRD 151
            + TG + +  N +     C + S  P    TS T  P++  G          T T     
Sbjct: 1864 DQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTAST 1923

Query: 152  GTRYVQKGEYRTNPED-IYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSP 210
            G+        RT P   +  +  T   V+S  ++  SS           +    P   S 
Sbjct: 1924 GSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS- 1982

Query: 211  WITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSN 270
             +T        TT    S T T TAT    T         PS +    HT+T +  T++ 
Sbjct: 1983 -VTPIPSSSLGTTWTRLSQTTTPTATMSTAT---------PSSTPETAHTSTVLTATATT 2032

Query: 271  TISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPS 330
            T + G               S +           +   +TT   F  T  +   T     
Sbjct: 2033 TGATG---------------SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA---- 2073

Query: 331  HSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPS 390
               P V + TTT  T   R  T        P + P   H        T    +   ATPS
Sbjct: 2074 -LTPPVWISTTT--TPTTRGSTV------TPSSIPGTTHTATVLTTTTTTVATGSMATPS 2124

Query: 391  STTEETATQKE--QWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDS 448
            S+T+ + T              G    P     +T      +   + P     T +P  +
Sbjct: 2125 SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSA 2184

Query: 449  SWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQS 508
              T    P+ + M   H  GR +   S H++    T +  +G++     T P ++T+   
Sbjct: 2185 LGTTHTPPVPNTMATTH--GRSLPPSSPHTVRTAWT-SATSGILGTTHITEPSTVTSHTL 2241

Query: 509  NSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTK 568
             + + +T H        HP++ T  S      + G   P H+  ++      T   P   
Sbjct: 2242 AATTGTTQHSTPALSSPHPSSRTTES----PPSPGTTTPGHTTATSRTTATAT---PSKT 2294

Query: 569  ESRTFIPVTSAKTGSFGVTAVTVG-DSNSNVNRSLSGDQDTFHPSGGSHTTHGS 621
             + T +P  S+ T +   T VT+G +     +  L        PSGG   T+ +
Sbjct: 2295 RTSTLLP--SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSN 2346



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 117/558 (20%), Positives = 194/558 (34%), Gaps = 78/558 (13%)

Query: 91   IHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFD-----GPITI 145
            IHP+S     +T   + T  T+   T   +  +        +T+L  A       GP T 
Sbjct: 3097 IHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGP-TA 3155

Query: 146  TIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGG-----YIFYTFST 200
            T  +  GT ++             PS      V +GS++  SST         +  T +T
Sbjct: 3156 TPSSTPGTTWILTE----------PSTTATVTVPTGSTATASSTRATAGTLKVLTSTATT 3205

Query: 201  VHPIPDEDSPWITDSTD------RIPATTLMSTSATATETA------TKRQETWDWFSWL 248
               I    +P  +  T       R  ATT  +TS TA  ++      T+  +T    + +
Sbjct: 3206 PTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATM 3265

Query: 249  FL--PSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISS 306
                PS +   +HT+T +  T++ T + G               S +           + 
Sbjct: 3266 STATPSSTPETVHTSTVLTTTTTTTRATG---------------SVATPSSTPGTAHTTK 3310

Query: 307  TISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPP 366
              +TT   F  T  +   T        P V + TTT  T   R  T        P + P 
Sbjct: 3311 VPTTTTTGFTATPSSSPGTA-----LTPPVWISTTT--TPTTRGSTV------TPSSIPG 3357

Query: 367  LIHHEHHEEEETPHSTSTIQATPSSTTEETATQKE--QWFGNRWHEGYRQTPKEDSHSTT 424
              H        T    +   ATPSS+T+ + T              G    P     +T 
Sbjct: 3358 TTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTP 3417

Query: 425  GTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPT 484
                 +   + P    +T +P  +  T    P+ +     H  GR +   S H++    T
Sbjct: 3418 IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTH--GRSLPPSSPHTVRTAWT 3475

Query: 485  ANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGR 544
             +  +G++     T P ++T+    + + +T H        HP++ T  S      + G 
Sbjct: 3476 -SATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTES----PPSPGT 3530

Query: 545  RDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVG-DSNSNVNRSLS 603
              P H+ G++      T   P    + T +P  S+ T +   T VT G +     +  L 
Sbjct: 3531 TTPGHTRGTSRTTATAT---PSKTRTSTLLP--SSPTSAPITTVVTTGCEPQCAWSEWLD 3585

Query: 604  GDQDTFHPSGGSHTTHGS 621
                   PSGG   T+ +
Sbjct: 3586 YSYPMPGPSGGDFDTYSN 3603



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 110/539 (20%), Positives = 180/539 (33%), Gaps = 79/539 (14%)

Query: 117  YCFNASAPPEEDCTSVTDLPNAFDGPI--------TITIVNRDGTRYVQKGEYRTNPEDI 168
            +C N    P    TS T +P++  G          T T     G+         T     
Sbjct: 2410 FCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILT 2469

Query: 169  YPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDS----------TDR 218
             PS      V +GS++  SST       T  T H      +P +T S             
Sbjct: 2470 EPSTTATVTVPTGSTATASSTQA-----TAGTPHVSTTATTPTVTSSKATPFSSPGTATA 2524

Query: 219  IPATTLMSTSATATE----TATKRQETWDWFSWLFLP---------SESKNHLHTTTQMA 265
            +PA    +T+ TAT      ++    TW   S    P         S +   +HT+T + 
Sbjct: 2525 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 2584

Query: 266  GTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWT 325
             T++ T + G               S +           +  ++TT   F  T  +   T
Sbjct: 2585 TTATTTGATG---------------SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGT 2629

Query: 326  QWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTI 385
                + + P  +  TTT  T     G+T       P + P   H        T    +  
Sbjct: 2630 ----ARTLPVWISTTTTPTT----RGSTV-----TPSSIPGTTHTPTVLTTTTTTVATGS 2676

Query: 386  QATPSSTTEETATQKE--QWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTP 443
             ATPSS+T+ + T              G    P     +T      +   + P    +T 
Sbjct: 2677 MATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTV 2736

Query: 444  SPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSM 503
            +P  +  T    P+ +     H  GR +   S H++    T +  +G +     T P + 
Sbjct: 2737 TPSSALGTTHTPPVPNTTATTH--GRSLSPSSPHTVRTAWT-SATSGTLGTTHITEPSTG 2793

Query: 504  TTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSH 563
            T+    + + +T H        HP++ T  S      + G   P H+  ++      T  
Sbjct: 2794 TSHTPAATTGTTQHSTPALSSPHPSSRTTES----PPSPGTTTPGHTRATSRTTATAT-- 2847

Query: 564  YPHTKESRTFIPVTSAKTGSFGVTAVTVG-DSNSNVNRSLSGDQDTFHPSGGSHTTHGS 621
             P    + T +P  S+ T +   T VT+G +     +  L        PSGG   T+ +
Sbjct: 2848 -PSKTRTSTLLP--SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSN 2903



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 98/435 (22%), Positives = 142/435 (32%), Gaps = 56/435 (12%)

Query: 170  PSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSA 229
            PS      V +GS++  SST         ST    P   S   T S+    AT L +  +
Sbjct: 4456 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRS 4515

Query: 230  TATE-TATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDR 288
            TAT  TAT         S+  +PS S     T T+++ T++ T +          +    
Sbjct: 4516 TATTPTAT---------SFTAIPSSSLGT--TWTRLSQTTTPTATMSTATPSSTPETVHT 4564

Query: 289  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQW---NPSHS-----NPEVLLQT 340
                + +          +T S+TP     TK     T      PS S      P V + T
Sbjct: 4565 STVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIST 4624

Query: 341  TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 400
            TT  T       T       P + P   H        T    +   ATPSS+T+ + T  
Sbjct: 4625 TTTPTTTT---PTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTP- 4680

Query: 401  EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHP 460
                           P   + +TT TA  S        G T  +P  +S        S  
Sbjct: 4681 ---------------PSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSK 4725

Query: 461  MGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDL---DRTGPLSMTTQQSNSQSFSTSH 517
                        +    S   + TA   T +         T P   TT  S   + ST H
Sbjct: 4726 ATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMS---TMSTIH 4782

Query: 518  EGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVT 577
                 +  H +T   T++     T     P+ + G+T +L   T+              T
Sbjct: 4783 TSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTT-----------TATT 4831

Query: 578  SAKTGSFGVTAVTVG 592
            +A TGS    + T G
Sbjct: 4832 TAATGSTATLSSTPG 4846



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 49/217 (22%), Positives = 76/217 (35%), Gaps = 27/217 (12%)

Query: 381  STSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR 440
            +T+T   +  ST   ++T    W           T    S +T  +  A+A T H     
Sbjct: 3701 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA 3760

Query: 441  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGP 500
            TTP+   S  T F +P           G    + +  S    PTA   T +      T  
Sbjct: 3761 TTPTVTSSKATPFSSP-----------GTATALPALRSTATTPTATSFTAIPSSSLGTTW 3809

Query: 501  LSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS------- 553
              ++   + + + ST+      +  H +T   T++     TG    P+ + G+       
Sbjct: 3810 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVP 3869

Query: 554  TTLLEGYT---SHYPHTKE------SRTFIPVTSAKT 581
            TT   G+T   S  P T        S T  P TS  T
Sbjct: 3870 TTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGST 3906



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 120/526 (22%), Positives = 181/526 (34%), Gaps = 74/526 (14%)

Query: 122  SAPPEEDCTSVTDLPNAFDGPI------TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTD 175
            S   +   TSVT +P++  G        T T V    T +       T+   +  +  T 
Sbjct: 4316 STATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATT 4375

Query: 176  DDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTD----------RIPATTLM 225
               +S +S+  S+    +I    +T         P  T S+              ATT  
Sbjct: 4376 TRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTA 4435

Query: 226  STSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENED- 284
            ST +TAT ++T         +W+     +   +   T    T+S+T +    P+      
Sbjct: 4436 STGSTATPSSTPGT------TWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 4489

Query: 285  ----ERDRHLSFSGSGIDDDEDFISSTIST-TPRAFDHTKQNQDWTQWNPSHSNPEVLLQ 339
                   +    S  G       + ST +T T  +F     +   T W         L Q
Sbjct: 4490 TPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR-------LSQ 4542

Query: 340  TTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEH--HEEEETPHSTSTIQATPSSTTEETA 397
            TTT          TA      P + P  +H          T  +T ++ ATPSST     
Sbjct: 4543 TTT---------PTATMSTATPSSTPETVHTSTVLTATATTTGATGSV-ATPSSTPGTAH 4592

Query: 398  TQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPI 457
            T K          G+  TP     S+ GTA             TT +P  S  T    P 
Sbjct: 4593 TTK---VPTTTTTGFTATPS----SSPGTALTPPVWISTTTTPTTTTPTTSGST--VTPS 4643

Query: 458  SHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSH 517
            S P G  H A  R+   ++ ++     A P++        T P   TT  + + + ST++
Sbjct: 4644 SIP-GTTHTA--RVLTTTTTTVATGSMATPSSS--TQTSGTPPSLTTTATTITATGSTTN 4698

Query: 518  EGLEEDKDHPTTSTLTSSNRND-VTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRT-FIP 575
                     P T  LTS+      T  +   + S  + T L   TS    TK + T F P
Sbjct: 4699 PS-STPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTS--TATKSTATSFTP 4755

Query: 576  VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGS 621
            + S+       T  TV    +    ++S    T H S    TTH S
Sbjct: 4756 IPSSTLW----TTWTVPAQTTTPMSTMS----TIHTSSTPETTHTS 4793



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 76/357 (21%), Positives = 124/357 (34%), Gaps = 56/357 (15%)

Query: 336  VLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLI----------HHEHHEEEETPHSTSTI 385
            +L + TT  T     G+TA   +    A PP +                   +P + +T+
Sbjct: 4252 ILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTL 4311

Query: 386  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGT-----AAASAHTSHPMQGR 440
                S+ T+ TAT       +    G   T  E + +   T      +++  T+H     
Sbjct: 4312 PVLTSTATKSTATSVTPIPSSTL--GTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVL 4369

Query: 441  TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNT--GLVEDLDRT 498
            TT +    + +    P S P          +   ++ +    PTA P++  G    L   
Sbjct: 4370 TTKATTTRATSSTSTPSSTPGTTWILT--ELTTAATTTAATGPTATPSSTPGTTWILTEL 4427

Query: 499  GPLSMTTQQSNSQSFSTSHEG----LEEDKDH-----PTTSTLTSSNRN----------- 538
               + TT  + S +  +S  G    L E         PT ST T+S+             
Sbjct: 4428 TTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTT 4487

Query: 539  ----DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT----AVT 590
                 VT  +  P+ S G+ T L    S    T  + T    T+  + S G T    + T
Sbjct: 4488 ATTPTVTSSKATPSSSPGTATALPALRS----TATTPTATSFTAIPSSSLGTTWTRLSQT 4543

Query: 591  VGDSNSNVNRSLSGDQDTFHPS---GGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 644
               + +    + S   +T H S     + TT G+     +  S  G A+TT  P  T
Sbjct: 4544 TTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 4600



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 73/348 (20%), Positives = 119/348 (34%), Gaps = 66/348 (18%)

Query: 336  VLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLI----------HHEHHEEEETPHSTSTI 385
            +L + TT  T     G+TA   +    A PP +                   +P + +T+
Sbjct: 2995 ILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTL 3054

Query: 386  QATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSP 445
                S+ T+ TAT             +   P   +  TTGT      T+ PM   +T  P
Sbjct: 3055 PVLTSTATKSTAT------------SFTPIP-SFTLGTTGT--LPEQTTTPMATMSTIHP 3099

Query: 446  EDSSWTDFFNPISHPMGRGHQAGRRMDMDSS----------------HSITLQPTANPN- 488
              +  T   + +        +A   M   SS                 +    PTA P+ 
Sbjct: 3100 SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSS 3159

Query: 489  ----TGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTS-SNRNDVTGG 543
                T ++ +   T  +++ T  + + S + +  G        T   LTS +    V   
Sbjct: 3160 TPGTTWILTEPSTTATVTVPTGSTATASSTRATAG--------TLKVLTSTATTPTVISS 3211

Query: 544  RRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT----AVTVGDSNSNVN 599
            R  P+ S G+ T L    S    T  + T   VT+  + S G      + T   + +   
Sbjct: 3212 RATPSSSPGTATALPALRS----TATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMST 3267

Query: 600  RSLSGDQDTFHPS---GGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 644
             + S   +T H S     + TT  +     +  S  G A+TT  P  T
Sbjct: 3268 ATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTT 3315


>gi|61743978 stabilin 1 precursor [Homo sapiens]
          Length = 2570

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 5/102 (4%)

Query: 23   DLNITCRFAGVFHVEK-NGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGF 81
            DL+   + AGVFH++  +G Y ++ +EA   C+A  + L +  Q+  A  +GF  C  G+
Sbjct: 2199 DLHFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGW 2258

Query: 82   I-EGHVVIPRIHPNSICAANNTGVYILTSN---TSQYDTYCF 119
            +  G    P + P + C     G+  L +    + ++D YCF
Sbjct: 2259 LANGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCF 2300


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 83/389 (21%), Positives = 136/389 (34%), Gaps = 52/389 (13%)

Query: 289  HLSFSGSGIDDDE----DFISSTISTTPRAFDHTKQNQDWTQWNP---SHSNPEVLLQTT 341
            H   SGS   D E    D  + ++S   +A  H + +Q+ T+      S  +   L Q +
Sbjct: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 2419

Query: 342  TRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS-----TIQATP-SSTTEE 395
            T       +G T         +H           + + HSTS     TI   P SS+   
Sbjct: 2420 THEQSESAHGRTGTSTGGRQGSH------HKQARDSSRHSTSQEGQDTIHGHPGSSSGGR 2473

Query: 396  TATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFN 455
              +  EQ      H G        SH +  T+   +  SH   G  + S +  +     +
Sbjct: 2474 QGSHYEQLVDRSGHSG--------SHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGD 2525

Query: 456  PISHPMGRGHQAGRRMDMDSSHSITLQPTANPNT------GLVEDLDRTGPLSMTTQQSN 509
               H   R H+A  R D      +    +  P T         +D D  G    + + S 
Sbjct: 2526 GSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG 2585

Query: 510  SQS---FSTSHEGLEEDKDHPTT-------------STLTSSNRNDVT--GGRRDPNHSE 551
            S S     ++ E L +   HP +             S+  S  R+  T  GG+   +H +
Sbjct: 2586 SASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQ 2645

Query: 552  GSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHP 611
              ++  E + SH+  + +S     +   +  S    +   G S S  + +    +D+   
Sbjct: 2646 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 2705

Query: 612  SGGSHTTHGSESDGHSHGSQEGGANTTSG 640
            S  +H   GS    H   S  G +  TSG
Sbjct: 2706 SVSAHGQAGSHQQSHQE-SARGRSGETSG 2733



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 74/300 (24%), Positives = 103/300 (34%), Gaps = 50/300 (16%)

Query: 369 HHEHHEEEETPHSTSTIQATPSSTTE-------ETATQKEQWF---GNRWHEGYRQTPKE 418
           H   H+E+   H  S   +  S T         +TA+  EQ     G R   G++Q+   
Sbjct: 335 HPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS 394

Query: 419 DSHSTTGTA-AASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRG--------HQ--- 466
             HS TG   A+SA +    +G +     DS      +      G G        HQ   
Sbjct: 395 SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQEST 454

Query: 467 ---AGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPL--SMTTQQSNSQSFSTSHEGLE 521
              +G R     S    +     P++        TG    S   Q  +S   S S EG +
Sbjct: 455 RGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQD 514

Query: 522 EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT 581
             + HP +S            G R  +H E S        SH+ HT         + A  
Sbjct: 515 TIRGHPGSSR-----------GGRQGSHHEQSVNRSGHSGSHHSHTTSQGR----SDASH 559

Query: 582 GSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 641
           G  G  +     S    N   SGD  T H SG  H    S++D   H   + G   +SGP
Sbjct: 560 GQSGSRSA----SRQTRNEEQSGD-GTRH-SGSRHHEASSQADSSRH--SQVGQGQSSGP 611



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 77/361 (21%), Positives = 124/361 (34%), Gaps = 42/361 (11%)

Query: 289  HLSFSGSGIDDDE----DFISSTISTTPRAFDHTKQNQDWTQWNP---SHSNPEVLLQTT 341
            H   SGS   D E    D  + ++S   +A  H + +Q+ T+      S  +   L Q +
Sbjct: 3656 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 3715

Query: 342  TRMTDVDRNG-----TTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE-E 395
            T       +G     T   +G+ + +A     H    E ++T      I+  P S     
Sbjct: 3716 THEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDT------IRGHPGSRRGGR 3769

Query: 396  TATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFN 455
              +  EQ      H G        SH +  T+   +  SH   G  + S E  +     +
Sbjct: 3770 QGSYHEQSVDRSGHSG--------SHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGD 3821

Query: 456  PISHPMGRGHQAGRRMDMDSSHSITLQPTA-----NPNTGLVEDLDRTGPLSMTTQQSNS 510
               H   R H+A  + D  S HS + Q  +     +   G     D          +  S
Sbjct: 3822 GSRHSGSRHHEASTQAD-SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRS 3880

Query: 511  QSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKES 570
            +S S +H G   ++    +    SS+R+  +  +  P  S+ ST    G+ S        
Sbjct: 3881 ESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAY 3940

Query: 571  RTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSL--------SGDQDTFHPSGGSHTTHGSE 622
             + I    +   S      + G         L        S D D +  SG  H+ HGS 
Sbjct: 3941 HSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYD-YGESGFRHSQHGSV 3999

Query: 623  S 623
            S
Sbjct: 4000 S 4000



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 68/376 (18%), Positives = 133/376 (35%), Gaps = 41/376 (10%)

Query: 288  RHLSFSGSGIDDDE----DFISSTISTTPRAFDHTKQNQDWTQ---WNPSHSNPEVLLQT 340
            RH   SGS   D E    +  + ++S   +A  H + +Q+  +      S  +   L Q 
Sbjct: 3331 RHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQV 3390

Query: 341  TTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQK 400
            +T       +G T         +H        HE+       S  Q    +      + +
Sbjct: 3391 STHEQSESAHGRTRTSTGRRQGSH--------HEQARDSSRHSASQEGQDTIRGHPGSSR 3442

Query: 401  EQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHP 460
                G+ + +   ++    SH +  T+   +  S    G  + S +  +     +   H 
Sbjct: 3443 RGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHS 3502

Query: 461  MGRGHQAGRRMDMDSSHSITLQ-------PTANPNTGLVEDLDRTGPLSMTTQQSNSQSF 513
                H+A  + D  S HS + Q        + N  + + +D D  G    + + S S S 
Sbjct: 3503 WSHHHEASTQAD-SSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 3561

Query: 514  STSHEGLEEDKD---HPTT---------STLTSSNRN------DVTGGRRDPNHSEGSTT 555
            +      E+ +D   HPT+          +  SS ++      + +GG+   +H +  ++
Sbjct: 3562 NHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSS 3621

Query: 556  LLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGS 615
              E + SH+  + +S     +   +  S    +   G S S  + S    +D+   S  +
Sbjct: 3622 AGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSA 3681

Query: 616  HTTHGSESDGHSHGSQ 631
            H   G     H   ++
Sbjct: 3682 HGQAGPHQQSHQESTR 3697



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 75/402 (18%), Positives = 136/402 (33%), Gaps = 54/402 (13%)

Query: 252  SESKNHLHTTTQMAGTSSNTI--SAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTIS 309
            S+S+ H   + + +G++S     S   +    +   R  H   +G G   D    S T  
Sbjct: 3219 SDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRH 3278

Query: 310  TTPRAFDHTKQNQDWTQWNPS--HSNPEVLLQTTTRMTDVDRNGTTAY---EGNWNPEAH 364
                +      + +  + +P   H +       ++R + + R   ++      +W     
Sbjct: 3279 AETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGS 3338

Query: 365  PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQW-----FGNRWHEGYRQTPKED 419
                   H EE +T   +   QA P   + + + +          G+  ++       E 
Sbjct: 3339 QASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSES 3398

Query: 420  SHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSI 479
            +H  T T+      SH  Q R   S   S+  +  + I     RGH    R     SH  
Sbjct: 3399 AHGRTRTSTGRRQGSHHEQARD--SSRHSASQEGQDTI-----RGHPGSSRRGRQGSH-- 3449

Query: 480  TLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRND 539
                         + +DR+G        + SQ  S +  G    +   + S  T ++   
Sbjct: 3450 -----------YEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR---SASRQTRNDEQS 3495

Query: 540  VTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVN 599
              G R   +H   ++T  +  +S +  + + ++  P TS   GS                
Sbjct: 3496 GDGSRHSWSHHHEASTQAD--SSRHSQSGQGQSAGPRTSRNQGS---------------- 3537

Query: 600  RSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 641
             S+S D D+   S  S    GS S  H   +QE   + +  P
Sbjct: 3538 -SVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHP 3578



 Score = 36.6 bits (83), Expect = 0.087
 Identities = 64/304 (21%), Positives = 105/304 (34%), Gaps = 43/304 (14%)

Query: 372 HHEE--EETPHSTS-----TIQATP-SSTTEETATQKEQWFGNRWHEGYRQTPKEDSHST 423
           HHE+  + + HS S     TI+  P SS      +  EQ      H G        SH +
Sbjct: 496 HHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSG--------SHHS 547

Query: 424 TGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQP 483
             T+   +  SH   G  + S +  +     +   H   R H+A  + D      +    
Sbjct: 548 HTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQ 607

Query: 484 TANPNT------GLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKD------------ 525
           ++ P T       + +D D  G    + + S S S +      E+ +D            
Sbjct: 608 SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDR 667

Query: 526 ----HPTTSTLTSSNRN--DVTGGRRDPNHSEGSTTLLEGYTS-HYPHTKESRTFIPVTS 578
               H   S+  S  R+  + + G+   +H +  ++  E + S H   + +S        
Sbjct: 668 AGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH 727

Query: 579 AKTGSFGVTAVTVGDSNSNVNRS--LSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGAN 636
            +  S    +   G S S    S   S D DT   SG     H  +S   S   + G  +
Sbjct: 728 GQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERS 787

Query: 637 TTSG 640
             SG
Sbjct: 788 RRSG 791



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 68/376 (18%), Positives = 116/376 (30%), Gaps = 36/376 (9%)

Query: 294  GSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTT 353
            G   + D   +S      P    H +  +DW+      S   +   +T   ++     T 
Sbjct: 1076 GHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTR 1135

Query: 354  AYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE-ETATQKEQWFGNRWHEGY 412
               G      H        H   +      TI+A P S       +  EQ      H G 
Sbjct: 1136 TSTGRRQGSHHEQARDSSRHSASQ--EGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSG- 1192

Query: 413  RQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMD 472
                   SH +  T+   +  SH   G  + S +        +   H   R H+A    D
Sbjct: 1193 -------SHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245

Query: 473  MDSSHSITLQPTANPNT----GLVEDLDRTGPLSMTTQQSNSQSFSTSHEG--LEEDKD- 525
                  +  + ++   T    G     D          +  S S S +H G   E+ +D 
Sbjct: 1246 SSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDG 1305

Query: 526  ---------------HPTTSTLTSSNRNDVTG--GRRDPNHSEGSTTLLEGYTSHYPHTK 568
                           H   S+  S   +  +   G+   +H +  ++  E + S +  + 
Sbjct: 1306 SRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSA 1365

Query: 569  ESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSH 628
            +S     +   +  S    +   G S S V  S    +D+   S  +H   G     H  
Sbjct: 1366 DSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425

Query: 629  GSQEGGANTTSGPIRT 644
             S  G +  +SG  R+
Sbjct: 1426 -SARGQSGESSGRSRS 1440



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 86/401 (21%), Positives = 133/401 (33%), Gaps = 77/401 (19%)

Query: 256  NHLHTTTQ-----MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTIST 310
            +H HTT+Q       G S +  ++    NEE   +  RH     SG    E    + IS 
Sbjct: 2815 HHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRH-----SGSRHHEASTHADISR 2869

Query: 311  TPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHH 370
              +A               S  +     Q ++   D D  G +     W+  A     HH
Sbjct: 2870 HSQAVQ-----------GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRN--HH 2916

Query: 371  EHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAAS 430
               +E+    S       P S  E+ A            +  RQ+    + +++G  AAS
Sbjct: 2917 GSAQEQLRDGSRH-----PRSHQEDRAGHGHS------ADSSRQSGTRHTQTSSGGQAAS 2965

Query: 431  AHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTG 490
            +H     Q R++      S        S   G GH        DS H       A+ N G
Sbjct: 2966 SHE----QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG 3021

Query: 491  LVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHS 550
              ED D        TQ  ++   + SH+   ++         ++  R+  T G       
Sbjct: 3022 HSEDSD--------TQSVSAHGQAGSHQQSHQE---------SARGRSGETSGH------ 3058

Query: 551  EGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFH 610
              S + L   ++H           P T  + GS    A    DS+ +       D    H
Sbjct: 3059 --SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQA---QDSSRHSASQYGQDTIRGH 3113

Query: 611  PSG------GSHTTHGSESDG-----HSHGSQEGGANTTSG 640
            P        G H  H  +S G     HSH + +G ++ + G
Sbjct: 3114 PGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG 3154



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 83/406 (20%), Positives = 140/406 (34%), Gaps = 61/406 (15%)

Query: 252  SESKNHLHTTTQMAGTSS-NTISAGWEPNEE-NEDERDRHLSFSGSGIDDDEDFISSTIS 309
            S+S+ H   + + +G++S N + + WE + + +      H   +G G   D    S T  
Sbjct: 1922 SDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRH 1981

Query: 310  TTPR-----AFDHTKQNQDWTQWNPSH-------SNPEVLLQTTTRMTDVDRNGTTAYEG 357
            T        A  H +      + + SH       S+    +      + V  +G   Y G
Sbjct: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSG 2041

Query: 358  NWNPEAHPPLIHHEHHEEEETPHSTSTIQATP--SSTTEETATQKEQWFGNRWHEGYRQT 415
            +   ++        H E+ +T   ++  +A P   S  E    Q  +  G      Y+ +
Sbjct: 2042 SQASDSEG------HSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095

Query: 416  PKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDS 475
              E S ST G +A S   +   QG      +DSS           + RGH    R     
Sbjct: 2096 THEQSESTHGQSAPS---TGGRQGSHYDQAQDSSRHSASQEGQDTI-RGHPGPSRGGRQG 2151

Query: 476  SHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSS 535
            SH               + +DR+G        + SQ  S +  G    +   + S  T  
Sbjct: 2152 SHQ-------------EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR---SASRKTYD 2195

Query: 536  NRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSN 595
                  G R   +H   +++  +  +S +    + ++  P TS   GS            
Sbjct: 2196 KEQSGDGSRHSGSHHHEASSWAD--SSRHSLVGQGQSSGPRTSRPRGS------------ 2241

Query: 596  SNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 641
                 S+S D D+   S  S    GS S  H   +QE   + +  P
Sbjct: 2242 -----SVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHP 2282



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 90/424 (21%), Positives = 134/424 (31%), Gaps = 71/424 (16%)

Query: 256  NHLHTTTQMAGTSSNTISAGWEPNEENEDERD----------RHLSFSGSGIDDDEDFIS 305
            +H HTT+Q    +S   S     + +  D+             H   S          + 
Sbjct: 2167 HHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVG 2226

Query: 306  STISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHP 365
               S+ PR       +      +  HS       +  R     RN   + +      +  
Sbjct: 2227 QGQSSGPRTSRPRGSSVSQDSDSEGHSE-----DSERRSGSASRNHHGSAQEQSRDGSRH 2281

Query: 366  PLIHHE----HHEEEETPHSTSTIQATPSSTTEETAT--QKEQWFGNRWHEGYRQTPKED 419
            P  HHE    H    E+   + T  A  SS  +  ++  Q     G R    ++Q+    
Sbjct: 2282 PRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2341

Query: 420  SHSTTGTA-AASAHTSHPMQGRTTPSPEDSSW----TDFFNPISHPMG-----------R 463
             HS  G   A+SA      +G +     DS      +D  +  +H              R
Sbjct: 2342 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTR 2401

Query: 464  GHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPL------SMTTQQSNSQSFSTSH 517
            G  AGR      S S   Q + +  +       RTG        S   Q  +S   STS 
Sbjct: 2402 GRSAGR---SGRSGSFLYQVSTHEQSESAH--GRTGTSTGGRQGSHHKQARDSSRHSTSQ 2456

Query: 518  EGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVT 577
            EG +    HP +S+           G R  +H E          SH+ HT  S+     +
Sbjct: 2457 EGQDTIHGHPGSSS-----------GGRQGSHYEQLVDRSGHSGSHHSHT-TSQGRSDAS 2504

Query: 578  SAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANT 637
               +GS   +  T  D  S          D    SG  H  H + S   S G  + G   
Sbjct: 2505 HGHSGSRSASRQTRNDEQSG---------DGSRHSGSRH--HEASSRADSSGHSQVGQGQ 2553

Query: 638  TSGP 641
            + GP
Sbjct: 2554 SEGP 2557



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 81/385 (21%), Positives = 132/385 (34%), Gaps = 68/385 (17%)

Query: 293  SGSGIDDDE----DFISSTISTTPRAFDHTKQNQDWTQWNP---SHSNPEVLLQTTTRMT 345
            SGS   D E    +  + ++S   +A  H + +Q+ T+      S  +   L Q +T   
Sbjct: 1715 SGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQ 1774

Query: 346  DVDRNGTTAYE-GNWNPEAHPPLIHHEHHEEEETPHSTSTIQATP-SSTTEETATQKEQW 403
                +G T    G      H        H   +      TI+  P SS      +  EQ 
Sbjct: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQ--EGQDTIRGHPGSSRGGRQGSHYEQS 1832

Query: 404  FGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGR 463
              +  H G        SH +  T+   +  S    G  + S +  +     +   H   R
Sbjct: 1833 VDSSGHSG--------SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSR 1884

Query: 464  GHQAGRRMDMDSSHSITLQPTANPNT------GLVEDLDRTGPLSMTTQQSNSQSFSTSH 517
             H+A  R D      +    ++ P T       + +D D  G    + + S S S +   
Sbjct: 1885 HHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLG 1944

Query: 518  EGLEEDKD----------------HPTTSTLTSSNRNDVTG--GRRDPNHSEGSTTLLEG 559
               E+ +D                H   S+  S  R+  +   G+   +H +  ++  E 
Sbjct: 1945 SAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGER 2004

Query: 560  YTSHYPHTKESRTFIPVTSAKTG-SFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTT 618
            + SH  H  +S      +S  +G   G  +  V DS    +R  SG Q            
Sbjct: 2005 HGSH--HQLQSAD----SSRHSGIGHGQASSAVRDSG---HRGYSGSQ------------ 2043

Query: 619  HGSESDGHSHGS--QEGGANTTSGP 641
              S+S+GHS  S  Q   A   +GP
Sbjct: 2044 -ASDSEGHSEDSDTQSVSAQGKAGP 2067



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 84/402 (20%), Positives = 138/402 (34%), Gaps = 88/402 (21%)

Query: 252 SESKNHLHTTTQMAGTSSNTI--SAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTIS 309
           S+S+ H   + + +G++S     SA  +  + +   R  H   +G G   D    S T  
Sbjct: 625 SDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRH 684

Query: 310 TTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIH 369
           T         QN    Q   SH           R +  +R+G+                 
Sbjct: 685 T---------QNSSSGQAASSHEQ--------ARSSAGERHGS----------------R 711

Query: 370 HEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKE------DSHST 423
           H+    + + HS  T     SS   ++        G+R   G + T  E      D+ S 
Sbjct: 712 HQLQSADSSRHS-GTGHGQASSAVRDS--------GHRGSSGSQATDSEGHSEDSDTQSV 762

Query: 424 TGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQP 483
           +G   A  H     +     S E S  +  F          +Q       +SSH  T   
Sbjct: 763 SGHGQAGHHQQSHQESARDRSGERSRRSGSFL---------YQVSTHKQSESSHGWT--- 810

Query: 484 TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTL--------TSS 535
              P+TG+     R G  S   Q  ++   S S +G +  + HP +S           S 
Sbjct: 811 --GPSTGV-----RQG--SHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSV 861

Query: 536 NRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS-FGVTAVTVGDS 594
           +R+  +G       S+G +    G +        SRT      ++ GS    +      S
Sbjct: 862 DRSGHSGSHHSHTTSQGRSDASRGQSGS---RSASRTTRNEEQSRDGSRHSGSRHHEASS 918

Query: 595 NSNVNRSLSGDQDTFHPSG-----GSHTTHGSESDGHSHGSQ 631
           +++++R     Q     S      GS  +  S+S+GHS  S+
Sbjct: 919 HADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960



 Score = 30.0 bits (66), Expect = 8.1
 Identities = 49/283 (17%), Positives = 87/283 (30%), Gaps = 34/283 (12%)

Query: 369  HHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAA 428
            HHEH  +      +     T    ++ +  Q      +R      Q+     HS +    
Sbjct: 3125 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHE 3184

Query: 429  ASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPN 488
            AS H       +      + S             R  + G  +  DS            +
Sbjct: 3185 ASTHADISRHSQAVQGQSEGS------------RRSRRQGSSVSQDSD-----------S 3221

Query: 489  TGLVEDLDRTGPL-------SMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVT 541
             G  ED +R           S+  Q  +      SH        H    +  S  R+  T
Sbjct: 3222 EGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAET 3281

Query: 542  --GGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVN 599
              GG+   +H +  ++  E + S +  + +S     +   +  S    +   G S S  +
Sbjct: 3282 SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQAS 3341

Query: 600  RSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQE--GGANTTSG 640
             S    +++   S   H   G     H   +++  GG +  SG
Sbjct: 3342 DSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSG 3384


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 115/513 (22%), Positives = 170/513 (33%), Gaps = 77/513 (15%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQ 263
               E +   T+S++   ATT+ S + TA+   ++   T    S     S   + +   T 
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI---TT 915

Query: 264  MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 323
            ++ T S T +A  E +E          S  GS +       S TI+ +    + T     
Sbjct: 916  VSTTGSETTTASTEGSETTT------ASTEGSELTTVSTTGSETITVSAEGSETTTVT-- 967

Query: 324  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS 383
             T  + + +      +TTT  T      T + EG+                       T+
Sbjct: 968  -TMGSETTTASTAGSETTTVSTAGSETTTASIEGS----------------------ETT 1004

Query: 384  TIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR--T 441
            T+ +T S TT  + T  E             T  E S +TT T A S  T+    G   T
Sbjct: 1005 TVSSTGSETTTVSTTGTETTI----------TSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 442  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLV-------E 493
            T S E S  T      S              + +S S  T   TA   T  V        
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 494  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS 553
                 G  + T   ++S++ + S  G E      T S  T+ +             SE +
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 554  TTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ 606
            TT  EG  +    T  S T           T++ +GS   TA T G   S  + + S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 607  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
              F    GS TT  S +      +   G+ TT+
Sbjct: 1235 TAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 114/513 (22%), Positives = 170/513 (33%), Gaps = 77/513 (15%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQ 263
               E +   T+S++   ATT+ S + TA+   ++   T    S     S   + +   T 
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI---TT 915

Query: 264  MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 323
            ++ T S T +A  E +E          S  GS +       S TI+ +    + T     
Sbjct: 916  VSTTGSETTTASTEGSETTT------ASTEGSELTTVSTTGSETITVSAEGSETTTVT-- 967

Query: 324  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS 383
             T  + + +      +TTT  T      T + EG+                       T+
Sbjct: 968  -TMGSETTTASTAGSETTTVSTAGSETTTASIEGS----------------------ETT 1004

Query: 384  TIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR--T 441
            T+ +T S TT  + T  E             T  E S +TT T A S  T+    G   T
Sbjct: 1005 TVSSTGSETTTVSTTGTETTI----------TSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 442  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLV-------E 493
            T S E S  T      S              + +S S  T   TA   T  V        
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 494  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS 553
                 G  + T   ++S++ + S  G E      T S  T+ +             SE +
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 554  TTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ 606
            TT  EG  +    T  S T           T++ +GS   TA T G   S  + + S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 607  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
              F    GS +T  S +      +   G+ TT+
Sbjct: 1235 TAF--IIGSESTIASTASLEPTATSLTGSETTT 1265



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 728  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 787

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 788  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 846

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 847  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 906

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 907  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 949

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 950  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 1003

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 1004 TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1056

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1057 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1116

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1117 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1166



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 261 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 319

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 320 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 379

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 380 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 421

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 422 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 463

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 464 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 518

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 519 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 578

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 579 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 629

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 630 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 686

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 687 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 746

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 747 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 801

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 802 ETTMASTI 809



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 115/513 (22%), Positives = 170/513 (33%), Gaps = 77/513 (15%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 834  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 882

Query: 204  IPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQ 263
               E +   T+S++   ATT+ S + TA+   ++   T    S     S   + +   T 
Sbjct: 883  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI---TT 936

Query: 264  MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 323
            ++ T S T +A  E +E          S  GS +       S TI+ +    + T     
Sbjct: 937  VSTTGSETTTASTEGSETTT------ASTEGSELTTVSTTGSETITVSAEGSETTTVT-- 988

Query: 324  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS 383
             T  + + +      +TTT  T      T + EG+                       T+
Sbjct: 989  -TMGSETTTASTAGSETTTVSTAGSETTTASIEGS----------------------ETT 1025

Query: 384  TIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR--T 441
            T+ +T S TT  + T  E             T  E S +TT T A S  T+    G   T
Sbjct: 1026 TVSSTGSETTTVSTTGTETTI----------TSTEGSETTTVTTAGSETTAVYTTGSETT 1075

Query: 442  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLV-------E 493
            T S E S  T      S              + +S S  T   TA   T  V        
Sbjct: 1076 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1135

Query: 494  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS 553
                 G  + T   ++S++ + S  G E      T S  T+ +             SE +
Sbjct: 1136 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1195

Query: 554  TTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ 606
            TT  EG  +    T  S T           T++ +GS   TA T G   S  + + S   
Sbjct: 1196 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1255

Query: 607  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
              F    GS TT  S +      +   G+ TT+
Sbjct: 1256 TAF--IIGSETTIASTASLEPTATSLTGSETTT 1286



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 149 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 206

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 207 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 265

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 266 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 318

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 319 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 378

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 379 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 432

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 433 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 488

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 489 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 535

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 536 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 595

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 596 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 654

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 655 TTASTEGSETTTVSTT 670



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 180 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 238

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 239 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 289

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 290 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 341

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 342 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 384

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 385 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 416

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 417 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 474

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 475 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 526

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 527 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 581



 Score = 33.1 bits (74), Expect = 0.96
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 44  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 103

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 104 SGT---TTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 159

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 160 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 216

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 217 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 256


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 115/513 (22%), Positives = 170/513 (33%), Gaps = 77/513 (15%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQ 263
               E +   T+S++   ATT+ S + TA+   ++   T    S     S   + +   T 
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI---TT 915

Query: 264  MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 323
            ++ T S T +A  E +E          S  GS +       S TI+ +    + T     
Sbjct: 916  VSTTGSETTTASTEGSETTT------ASTEGSELTTVSTTGSETITVSAEGSETTTVT-- 967

Query: 324  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS 383
             T  + + +      +TTT  T      T + EG+                       T+
Sbjct: 968  -TMGSETTTASTAGSETTTVSTAGSETTTASIEGS----------------------ETT 1004

Query: 384  TIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR--T 441
            T+ +T S TT  + T  E             T  E S +TT T A S  T+    G   T
Sbjct: 1005 TVSSTGSETTTVSTTGTETTI----------TSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 442  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLV-------E 493
            T S E S  T      S              + +S S  T   TA   T  V        
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 494  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS 553
                 G  + T   ++S++ + S  G E      T S  T+ +             SE +
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 554  TTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ 606
            TT  EG  +    T  S T           T++ +GS   TA T G   S  + + S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 607  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
              F    GS TT  S +      +   G+ TT+
Sbjct: 1235 TAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 115/513 (22%), Positives = 170/513 (33%), Gaps = 77/513 (15%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQ 263
               E +   T+S++   ATT+ S + TA+   ++   T    S     S   + +   T 
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI---TT 915

Query: 264  MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 323
            ++ T S T +A  E +E          S  GS +       S TI+ +    + T     
Sbjct: 916  VSTTGSETTTASTEGSETTT------ASTEGSELTTVSTTGSETITVSAEGSETTTVT-- 967

Query: 324  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS 383
             T  + + +      +TTT  T      T + EG+                       T+
Sbjct: 968  -TMGSETTTASTAGSETTTVSTAGSETTTASIEGS----------------------ETT 1004

Query: 384  TIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR--T 441
            T+ +T S TT  + T  E             T  E S +TT T A S  T+    G   T
Sbjct: 1005 TVSSTGSETTTVSTTGTETTI----------TSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 442  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLV-------E 493
            T S E S  T      S              + +S S  T   TA   T  V        
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 494  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS 553
                 G  + T   ++S++ + S  G E      T S  T+ +             SE +
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 554  TTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ 606
            TT  EG  +    T  S T           T++ +GS   TA T G   S  + + S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 607  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
              F    GS TT  S +      +   G+ TT+
Sbjct: 1235 TAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 129/608 (21%), Positives = 194/608 (31%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T  T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 114/513 (22%), Positives = 170/513 (33%), Gaps = 77/513 (15%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQ 263
               E +   T+S++   ATT+ S + TA+   ++   T    S     S   + +   T 
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI---TT 915

Query: 264  MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 323
            ++ T S T +A  E +E          S  GS +       S TI+ +    + T     
Sbjct: 916  VSTTGSETTTASTEGSETTT------ASTEGSELTTVSTTGSETITVSAEGSETTTVT-- 967

Query: 324  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS 383
             T  + + +      +TTT  T      T + EG+                       T+
Sbjct: 968  -TMGSETTTASTAGSETTTVSTAGSETTTASIEGS----------------------ETT 1004

Query: 384  TIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR--T 441
            T+ +T S TT  + T  E             T  E S +TT T A S  T+    G   T
Sbjct: 1005 TVSSTGSETTTVSTTGTETTI----------TSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 442  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLV-------E 493
            T S E S  T      S              + +S S  T   TA   T  V        
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 494  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS 553
                 G  + T   ++S++ + S  G E      T S  T+ +             SE +
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 554  TTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ 606
            TT  EG  +    T  S T           T++ +GS   TA T G   S  + + S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 607  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
              F    GS +T  S +      +   G+ TT+
Sbjct: 1235 TAF--IIGSESTIASTASLEPTATSLTGSETTT 1265



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 70/293 (23%), Positives = 109/293 (37%), Gaps = 47/293 (16%)

Query: 373 HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ---TPKEDSHSTTGTAA- 428
           H    +P +T +  +T SS   E +T      G+     +     TP    HSTT  ++ 
Sbjct: 23  HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 82

Query: 429 ---------ASAHTSHPMQGRTTPSPEDSSWTDFFNPISHP-MGRGHQAGRRMDMDSSHS 478
                    AS  TS P Q  TT      S     +P S   +  G ++        S  
Sbjct: 83  GSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTH 142

Query: 479 ITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED----KDHPTTSTLTS 534
            TL P +  ++G+VE   R    + + + + S + STS  GL+ +    + HP ++  T 
Sbjct: 143 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTP 201

Query: 535 SNRNDVTGGRRDP---NHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTV 591
           S  +  T    +    + S GST      T+H+P                     ++ T 
Sbjct: 202 SPPSTATAPVEESTTYHRSPGSTP-----TTHFP--------------------ASSTTS 236

Query: 592 GDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRT 644
           G S  +     S D     PS    TT G   +  +  SQ G  +TT+ P  T
Sbjct: 237 GHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDST 289



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 100/459 (21%), Positives = 155/459 (33%), Gaps = 92/459 (20%)

Query: 162 RTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIF-YTFSTV------HPIPDEDSPWITD 214
           R+    + P++ T   VS  S++  S     +   +  ST       H      SP  TD
Sbjct: 27  RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 86

Query: 215 STDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISA 274
           +T  +PA+T  +TS  + E+ T                       T T ++  S+  +S 
Sbjct: 87  TT-LLPAST--TTSGPSQESTTSHSSPGS----------------TDTALSPGSTTALSF 127

Query: 275 GWEPNEENEDERDRHL-----SFSGSGIDDDEDFISSTI-----------STTP------ 312
           G E    +      H      S + SGI +    + S+            ST+P      
Sbjct: 128 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 187

Query: 313 RAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEH 372
            AF     +   T   PS +   V  ++TT         TT +  +     H       H
Sbjct: 188 TAFQTHPASTHTTPSPPSTATAPVE-ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH 246

Query: 373 HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 432
              + +  + S+  +T S  +EE++T   Q        G   T      +TT   +    
Sbjct: 247 SSPDASGTTPSSAHSTTSGVSEESSTSHSQ-------PGSTHTTAFPDSTTTSGLSQEPT 299

Query: 433 TSHPMQGR------TTPSP-----------------EDSSWTDFFNPISHPMGRGHQAGR 469
           TSH  QG       TTPSP                   S+ T  F+  S  +GR  ++  
Sbjct: 300 TSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT 359

Query: 470 RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
                 S   T  P +    GL E          TT  S+ +S  T+           + 
Sbjct: 360 VHSSPGSTETTALPGSTTTAGLSE--------KSTTFYSSPRSPDTTLSPASTTSSGVSE 411

Query: 530 STLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTK 568
            + TS +R   T     P    GSTT + GY S  P ++
Sbjct: 412 ESTTSHSRPGSTHTTAFP----GSTT-MPGYHSIIPWSR 445


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 122/565 (21%), Positives = 210/565 (37%), Gaps = 84/565 (14%)

Query: 122  SAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSG 181
            ++P     T  T LP    G  T   ++   T +      R+    + P++ T   VS  
Sbjct: 4305 TSPISSGSTETTALP----GSTTTAGLSEKSTTFYSSP--RSPDTTLSPASTTSSGVSEE 4358

Query: 182  SSSERSSTSGGYIF-YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE 240
            S++  S     +   +  ST  P   ++S     ++   P +T  + S  +T  ++   E
Sbjct: 4359 STTSHSRPGSMHTTAFPSSTTMPGVSQEST----ASHSSPGSTDTTLSPGSTTASSLGPE 4414

Query: 241  TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 300
            +  + S       S     TT     T+++ +     P   +       LS +GS     
Sbjct: 4415 STTFHS-------SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG 4467

Query: 301  EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN 360
            E       STT +++ ++K   D T   P+ ++  V L TT+  +      TT +  +  
Sbjct: 4468 E-------STTFQSWPNSK---DTTPAPPTTTSAFVELSTTSHGSP-SSTPTTHFSASST 4516

Query: 361  PEAHPPLIHHEHHEEEETPHSTSTIQAT-PSSTTEETATQKEQWFGNRWHEGYRQTPKED 419
                         EE  T HS+    AT PS     T+   E+        G  QT    
Sbjct: 4517 TLGRS--------EESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFP 4568

Query: 420  SHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQA-----------G 468
              +TT      + TSH     T  S   ++      P S+    G  A           G
Sbjct: 4569 ESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG 4628

Query: 469  RRMDMDSSHSI-----TLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEED 523
            R  +  +SHS      T+   A   T ++     T P+S  + ++ +   ST+  GL E 
Sbjct: 4629 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK 4688

Query: 524  K----DHPTTSTLTSSNRNDVTGGRRD---------------PNHSEGSTT-LLEGYTSH 563
                   P+++  T  + +  T GR +               P+ +  +T+ L+E  T++
Sbjct: 4689 STTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAY 4748

Query: 564  YPHTKESRTF-IPVTSAKTG-------SFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGS 615
            +     ++T   P +S  +G       S   T  T+    S  + +L  +  ++H S GS
Sbjct: 4749 HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS-ALVEEPTSYHSSPGS 4807

Query: 616  -HTTHGSESDGHSHGSQEGGANTTS 639
              TTH  ES   S  S+E  A+ +S
Sbjct: 4808 IATTHFPESSTTSGRSEESTASHSS 4832



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 101/416 (24%), Positives = 152/416 (36%), Gaps = 57/416 (13%)

Query: 174  TDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATAT- 232
            T   +SSGS  E ++  G       ST  P   E S     S+ R PATTL   S T++ 
Sbjct: 939  TTSPISSGSM-ETTALPG-------STTTPGLSERSTTF-HSSPRSPATTLSPASTTSSG 989

Query: 233  ---ETATKRQETWDWFSWLFLPSESKNHL--HTTTQMAGTSSNTISAGWEPNEENEDERD 287
               E+ T R       +  F  S +   L  H+TT  +   S   +        +   ++
Sbjct: 990  VSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE 1049

Query: 288  RHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNP----EVLLQTTTR 343
               S S SG     D   S  STT  +F      Q+ T +   HSNP      L   +T 
Sbjct: 1050 STTSHSSSG---STDTALSPGSTTALSF-----GQESTTF---HSNPGSTHTTLFPDSTT 1098

Query: 344  MTDVDRNGTTAYEGNWNPE-------AHPPLIHHEHHEEEETPHSTSTIQATPSSTT--- 393
             + +    T  +    +P        +  P +  E    +  P ST T  + PS+ T   
Sbjct: 1099 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 1158

Query: 394  EETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDF 453
            EE+ T         +H     TP      TT   A+S  + H  +     S  D+S T  
Sbjct: 1159 EESTT---------YHRSPGSTP------TTHFPASSTTSGHSEKSTIFHSSPDASGTTP 1203

Query: 454  FNPISHPMGRGHQAGRRMDMDSSHSITLQ-PTANPNTGLVEDLDRTGPLSMTTQQSNSQS 512
             +  S   GRG     R+   S+   TL   T  P          + P S TT  S +  
Sbjct: 1204 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 1263

Query: 513  FSTS-HEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
             S    E     +  P ++  T S  +  T G  + + +  S++     T+ +PH+
Sbjct: 1264 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHS 1319



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 113/497 (22%), Positives = 179/497 (36%), Gaps = 89/497 (17%)

Query: 173  PTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATAT 232
            PT   +SSGS+ E ++  G       +T   + ++ + +   S+ R P TTL   S T++
Sbjct: 4303 PTTSPISSGST-ETTALPGS------TTTAGLSEKSTTFY--SSPRSPDTTLSPASTTSS 4353

Query: 233  ETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSF 292
              + +   +                +HTT   + T+   +S     +  +    D  LS 
Sbjct: 4354 GVSEESTTS----------HSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLS- 4402

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
             GS         S+T  ++P + + T    + T      ++  V   T +  T +   G+
Sbjct: 4403 PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGS 4462

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE--ETATQKEQWFGNRWHE 410
            T  +G             E    +  P+S  T  A P++T+   E +T          H 
Sbjct: 4463 TTRQG-------------ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTS--------HG 4501

Query: 411  GYRQTPKEDSHSTTGTAAASAHT----SHPMQGRTTPSPEDS--------SWTDFFNPIS 458
                TP     +++ T   S  +    S P+   TTPSP  S        S T   +P S
Sbjct: 4502 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGS 4561

Query: 459  ----HPMGRGHQAGRRMDMDSSHSITLQPTAN-PNT--GLVEDLDRTGPLSMTTQQSNSQ 511
                H       +GR  +  +SHS T    ++ P+T   LVE+         T+  S+  
Sbjct: 4562 TQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--------PTSYHSSPG 4613

Query: 512  SFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESR 571
            S +T+H          +  +  S +  D TG    P  S  S  L E  TS         
Sbjct: 4614 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS--------- 4664

Query: 572  TFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQ 631
               P++S   GS   TA+      S     LS    TFH S  S  T    +   + G  
Sbjct: 4665 ---PISS---GSMETTAL----PGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRS 4714

Query: 632  EGGANTTSGPIRTPQIP 648
            E      S P+ T   P
Sbjct: 4715 EESTTVHSSPVATATTP 4731



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 66/272 (24%), Positives = 93/272 (34%), Gaps = 28/272 (10%)

Query: 374  EEEETPHSTSTIQAT-PSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 432
            EE  T HS+    AT PS     T+   E+        G  QT      ST    +  + 
Sbjct: 1882 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 1941

Query: 433  TSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLV 492
            TSH     T  SP  ++      P S+    G  A      DSS   T    +  +T   
Sbjct: 1942 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFP-DSS---TTSGRSEESTASH 1997

Query: 493  EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVT--GGRRDPNHS 550
               D TG + +  + + S     S           TTS ++S +       G    P  S
Sbjct: 1998 SSQDATGTIVLPARSTTSVLLGES-----------TTSPISSGSMETTALPGSTTTPGLS 2046

Query: 551  EGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAV-TVGDSNSNVNRSLSGDQDTF 609
            E STT          H+        ++ A T S GV+   T   S      + +    T 
Sbjct: 2047 EKSTTF---------HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 2097

Query: 610  HPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 641
             P    H+T    S G +  +    + TTSGP
Sbjct: 2098 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2129



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 131/589 (22%), Positives = 200/589 (33%), Gaps = 73/589 (12%)

Query: 109  SNTSQYDTYCFNASAPP---EEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNP 165
            S  S   T  F+AS+      E+ T+V   P A     T     R  T  V  GE  T+P
Sbjct: 3169 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG---TALFPTRSATS-VLVGEPTTSP 3224

Query: 166  EDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTF-----STVHPIPDEDSPWITDST---D 217
                 S  T+     GS++    +     FY+      +T+ P     S    +ST    
Sbjct: 3225 ---ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 3281

Query: 218  RIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLH---TTTQMAGTSSNTISA 274
            R  +T   +   + T     ++ T    S    P  +   L    TT    G  S T  +
Sbjct: 3282 RPGSTHTTAFPGSTTMPGVSQESTASHSS----PGSTDTTLSPGSTTASSLGPESTTFHS 3337

Query: 275  GWEPNEENEDERDRHLSFSGSGIDDDEDFISSTIS---TTPRAFDHTKQNQDWTQWNPSH 331
            G  P          + + SG  ++      SST S   T   A   T+Q +  T  +  +
Sbjct: 3338 G--PGSTETTLLPDNTTASGL-LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPN 3394

Query: 332  SNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPHSTSTIQAT- 388
            S        TT    V+ + T+    +  P  H           EE  T HS+    AT 
Sbjct: 3395 SKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATT 3454

Query: 389  PSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDS 448
            PS     T+   E+        G  QT       TT      + TSH     T  S   +
Sbjct: 3455 PSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST 3514

Query: 449  SWTDFFNPISHPMGRGHQA-----------GRRMDMDSSHSI-----TLQPTANPNTGLV 492
            +      P S+    G  A           GR  +  +SHS      T+   A   T ++
Sbjct: 3515 TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 3574

Query: 493  EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKD-------HPTTSTLTSSNRNDVTGGRR 545
                 T P+S  + ++ +   ST+  GL E           P T+   +S  +       
Sbjct: 3575 LGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEES 3634

Query: 546  DPNHSEGSTTLLEGY--------------TSHYPHTKESRTFIPVTSAKTGSFGVTAVTV 591
              +HS   +T    +              TSH        T +P ++  +GS    + T 
Sbjct: 3635 TTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS-SQESTTS 3693

Query: 592  GDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSG 640
              S+ + + +LS    T    G   TT  S S G +H +    + T+SG
Sbjct: 3694 HSSSGSTDTALSPGSTTALSFGQESTTFHS-SPGSTHTTLFPDSTTSSG 3741



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 117/561 (20%), Positives = 190/561 (33%), Gaps = 97/561 (17%)

Query: 157  QKGEYRTNPEDIYPSNPTDDDVSSG----SSSERSSTSGGYIFYT--FSTVHPIPDEDS- 209
            Q   + ++P D   +   DD ++SG    S+   SST   +   T   ST   + +E + 
Sbjct: 1523 QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTT 1582

Query: 210  ----PWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLP---SESKNHLHTTT 262
                P  +D+T   P TT      + T  +         FS        SE    +H++ 
Sbjct: 1583 FQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 1642

Query: 263  QMAGT------SSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFD 316
               GT      S+ ++  G               +  GS         S+T  ++PR+ D
Sbjct: 1643 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD 1702

Query: 317  HTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEE 376
             T      T    S        ++TT  +      TTA+ G+       P +  E     
Sbjct: 1703 TTLSPASTTSSGVSE-------ESTTSHSRPGSTHTTAFPGSTTM----PGVSQESTASH 1751

Query: 377  ETPHSTSTIQATPSSTTEETATQKEQWFGN--------------------------RWHE 410
             +P ST T   +P STT  +   +   F +                              
Sbjct: 1752 SSPGSTDTT-LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSST 1810

Query: 411  GYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPE-----------------DSSWTDF 453
            G   T    + STT    ++   S P    T P+P                   S+ T  
Sbjct: 1811 GSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTH 1870

Query: 454  FNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSF 513
            F+  S  +GR  ++        + + T  P  +  +GLVE+         +TQ  +    
Sbjct: 1871 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPES 1930

Query: 514  STSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP----NHSEGSTTLLEGYTSHYPHT-- 567
            ST+    EE +   +++T T S+    T    +     + S GST      T+H+P +  
Sbjct: 1931 STASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTA-----TTHFPDSST 1985

Query: 568  ----KESRTFIPVTSAKTGSF-----GVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTT 618
                 E  T    +   TG+        T+V +G+S +  +   SG  +T    G + T 
Sbjct: 1986 TSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT--SPISSGSMETTALPGSTTTP 2043

Query: 619  HGSESDGHSHGSQEGGANTTS 639
              SE     H S    A T S
Sbjct: 2044 GLSEKSTTFHSSPRSPATTLS 2064



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 122/581 (20%), Positives = 200/581 (34%), Gaps = 84/581 (14%)

Query: 121  ASAPPEEDCTSVTDLPNAFDGPITIT--IVNRDGTRYVQKGEYRTN--PEDIYPSNPTDD 176
            AS   EE  TS +   +    P + T  +V    + +   G   T   P+    S  +++
Sbjct: 1933 ASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 1992

Query: 177  DVSSGSSSERSST------SGGYIFYTFSTVHPIPDED-----------SPWITD----- 214
              +S SS + + T      S   +    ST  PI               +P +++     
Sbjct: 1993 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTF 2052

Query: 215  -STDRIPATTLMSTSATAT----ETATKRQETWDWFSWLFLPSESKNHL--HTTTQMAGT 267
             S+ R PATTL   S T++    E+ T         +  F  S +   L  H+TT  +  
Sbjct: 2053 HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 2112

Query: 268  SSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFD------HTKQN 321
             S   +        +   ++   S S  G     D   S  STT  +F       H+   
Sbjct: 2113 GSTDTTLLPASTTTSGPSQESTTSHSSPG---STDTALSPGSTTALSFGQESTTFHSSPG 2169

Query: 322  QDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHP-PLIHHEHHEEEETPH 380
               T   P  +    +++ +TR+     + T +     +P +   P +  E    +  P 
Sbjct: 2170 STHTTLFPDSTTSSGIVEASTRV----HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 2225

Query: 381  STSTIQATPSSTT---EETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPM 437
            ST T  + PS+ T   EE+ T         +H     TP      TT   A+S  + H  
Sbjct: 2226 STHTTPSPPSTATAPVEESTT---------YHRSPGSTP------TTHFPASSTTSGHSE 2270

Query: 438  QGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE---- 493
            +     S  D+S T   +  S   GRG     R+   S+  IT  P +    GL E    
Sbjct: 2271 KSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST-EITTLPGSTTTPGLSEASTT 2329

Query: 494  -------DLDRTGPLSMTTQQSNSQS-FSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRR 545
                         P SMT+     +S  S S  G       P ++T    +    T    
Sbjct: 2330 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 2389

Query: 546  DPNHSEGS------TTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVN 599
             P  +E +      TT + G      H++ + T   + +  + + G+T  +     S  +
Sbjct: 2390 SPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS 2449

Query: 600  RSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSG 640
                          G  +T    S G +  +     +TTSG
Sbjct: 2450 TQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 104/430 (24%), Positives = 154/430 (35%), Gaps = 66/430 (15%)

Query: 174  TDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATAT- 232
            T   +SSGS  E ++  G       ST  P   E S     S+ R PATTL   S T++ 
Sbjct: 3579 TTSPISSGSM-ETTALPG-------STTTPGLSEKSTTF-HSSPRSPATTLSPASTTSSG 3629

Query: 233  ---ETATKRQETWDWFSWLFLPSESKNHL--HTTTQMA--GTSSNTISAGWEPNEENEDE 285
               E+ T         +  F  S +   L  H+TT  +  G++  T+         +  E
Sbjct: 3630 VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQE 3689

Query: 286  RDRHLSFSGSGIDDDEDFISSTISTTPRAFD------HTKQNQDWTQWNPSHSNPEVLLQ 339
                 S SGS      D   S  STT  +F       H+      T   P  +    +++
Sbjct: 3690 STTSHSSSGS-----TDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 3744

Query: 340  TTTRMTDVDRNGTTAYEGNWNPEAHP-PLIHHEHHEEEETPHSTSTIQATPSSTT---EE 395
             +TR+     + T +     +P +   P +  E    +  P ST T  + PS+ T   EE
Sbjct: 3745 ASTRV----HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 3800

Query: 396  TATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFN 455
            + T         +H     TP      TT   A+S  + H  +     S  D+S T   +
Sbjct: 3801 STT---------YHRSPGSTP------TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 3845

Query: 456  PISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE-----------DLDRTGPLSMT 504
              S   GRG     R+   S+  IT  P +    GL E                 P SMT
Sbjct: 3846 AHSTTSGRGESTTSRISPGST-EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 3904

Query: 505  TQQSNSQS-FSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSH 563
            +     +S  S S  G       P ++T    +    T     P  +E  TT+    T+ 
Sbjct: 3905 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE--TTVFPRSTTT 3962

Query: 564  YPHTKESRTF 573
                +E  TF
Sbjct: 3963 SVRREEPTTF 3972



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 98/487 (20%), Positives = 176/487 (36%), Gaps = 59/487 (12%)

Query: 174  TDDDVSSGSSSERSSTSGGYIFY-----TFSTVHPIPDEDSPWITDSTDRIPATTLMSTS 228
            TD  +S GS++  S       F+     T +T+ P     S  +  ST    +T    T+
Sbjct: 4397 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 4456

Query: 229  ATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDR 288
             +   + T++ E+  + SW        N   TT     T+S  +      +         
Sbjct: 4457 LSPAGSTTRQGESTTFQSW-------PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 4509

Query: 289  HLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWT------QWNPSHSNPEVLLQTTT 342
            H S S + +   E+  S+T+ ++P A   T      T      +    HS+P      +T
Sbjct: 4510 HFSASSTTLGRSEE--STTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPG-----ST 4562

Query: 343  RMTDVDRNGTTAYEGNWNPEAHPPLIH-------------HEHHEEEETPHSTSTIQATP 389
            +      + TT+  G  +  +H    H              E      +P ST+T     
Sbjct: 4563 QTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD 4622

Query: 390  SSTTEETATQKEQWFGNRWHEGYRQTPKEDSHS-------TTGTAAASAHTSHPMQGRTT 442
            SSTT   + +      ++   G    P   + S       T+  ++ S  T+      TT
Sbjct: 4623 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 4682

Query: 443  PSPEDSSWTDFFNPISHP----------MGRGHQAGRRMDMDSSHSITLQPTANPNTGLV 492
            P   + S T   +P S P          +GR  ++        + + T  P  +  +GLV
Sbjct: 4683 PGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 4742

Query: 493  EDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDK-DHPTTSTLTSSNRNDVTGGRRDPNHSE 551
            E+         +TQ  +    ST+    EE +  H +T+   SS  +  +    +P    
Sbjct: 4743 EESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH 4802

Query: 552  GSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHP 611
             S   +   T+H+P +  +      ++A   S     +T   ++   +  ++ +  TF+ 
Sbjct: 4803 SSPGSIA--TTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIA-ESTTFYI 4859

Query: 612  SGGSHTT 618
            S GS  T
Sbjct: 4860 SPGSMET 4866



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 109/508 (21%), Positives = 178/508 (35%), Gaps = 68/508 (13%)

Query: 163  TNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPAT 222
            + P  + PS+ T+     GS +  S +     FYT           SP   D+T   PAT
Sbjct: 2495 STPSRLSPSS-TETTTLPGSPTTPSLSEKSTTFYT-----------SPRSPDAT-LSPAT 2541

Query: 223  TLMSTSATATETATKRQETWDWFSWLFLPSESKNHL--HTTTQMAGTSSNTISAGWEPNE 280
            T  ++S  + E++T   +     +  F  S +   L  H+TT  +   S   +       
Sbjct: 2542 T--TSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 2599

Query: 281  ENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFD------HTKQNQDWTQWNPSHSNP 334
             +   ++   S S  G     D   S  STT  +F       H+      T   P  +  
Sbjct: 2600 TSGPSQESTTSHSSPG---STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 2656

Query: 335  EVLLQTTTRMTDVDRNGTTAYEGNWNPEAHP-PLIHHEHHEEEETPHSTSTIQATPSSTT 393
              +++ +TR+     + T +     +P +   P +  E    +  P ST T  + PS+ T
Sbjct: 2657 SGIVEASTRV----HSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTAT 2712

Query: 394  ---EETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSW 450
               EE+ T         +H     TP      TT   A+S  + H  +     S  D+S 
Sbjct: 2713 APVEESTT---------YHRSPGSTP------TTHFPASSTTSGHSEKSTIFHSSPDASG 2757

Query: 451  TDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE-----------DLDRTG 499
            T   +  S   GRG     R+   S+  IT  P +    GL E                 
Sbjct: 2758 TTPSSAHSTTSGRGESTTSRISPGST-EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 2816

Query: 500  PLSMTTQQSNSQS-FSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSE------G 552
            P SMT+     +S  S S  G       P ++T    +    T     P  +E       
Sbjct: 2817 PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRS 2876

Query: 553  STTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPS 612
            +TT + G      H++ + T   + +  + + G+T  +     S  +             
Sbjct: 2877 TTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD 2936

Query: 613  GGSHTTHGSESDGHSHGSQEGGANTTSG 640
             G  +T    S G +  +     +TTSG
Sbjct: 2937 LGEESTTFPSSSGSTGTTLSPARSTTSG 2964



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 107/509 (21%), Positives = 180/509 (35%), Gaps = 70/509 (13%)

Query: 170  PSNPTDD----DVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLM 225
            P +PT       ++S    E S+TS      T STV P     +P +++ +  + +++  
Sbjct: 3891 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA-STTTPGLSEESTTVYSSSPG 3949

Query: 226  STSAT----ATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEE 281
            ST  T    +T T+ +R+E   + S       +  H    T+ + TS  T  +   P   
Sbjct: 3950 STETTVFPRSTTTSVRREEPTTFHS-----RPASTHTTLFTEDSTTSGLTEESTAFPGSP 4004

Query: 282  NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTT 341
               +     + + + + ++     S+  +T       +     T      S P  L  ++
Sbjct: 4005 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST---TSGLVGESTPSRLSPSS 4061

Query: 342  TRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPHST-STIQATPSSTTEETAT 398
            T  T +  + TT           P L       +    +P +T S    T S  +EE++T
Sbjct: 4062 TETTTLPGSPTT-----------PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 4110

Query: 399  QKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTT---------------- 442
               Q        G   T      +TT   +    TSH  QG T                 
Sbjct: 4111 SHSQ-------PGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ 4163

Query: 443  -----PSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD- 496
                  SP D+  T      +   G    +        S   TL P ++ +TGL E+   
Sbjct: 4164 STTFHSSPGDTE-TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTT 4222

Query: 497  -RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTT 555
             ++ P S  T  S   + +   E        P+++  T  + +  T GR + + +  S+ 
Sbjct: 4223 FQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 4282

Query: 556  LLEGYTSHYPHTKESRTFI--PVTS-AKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPS 612
               G T+ +P    +   +  P TS   +GS   TA+      S     LS    TF+ S
Sbjct: 4283 GATG-TALFPTRSATSVLVGEPTTSPISSGSTETTAL----PGSTTTAGLSEKSTTFYSS 4337

Query: 613  GGSHTTHGSESDGHSHGSQEGGANTTSGP 641
              S  T  S +   S G  E    + S P
Sbjct: 4338 PRSPDTTLSPASTTSSGVSEESTTSHSRP 4366



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 72/312 (23%), Positives = 113/312 (36%), Gaps = 46/312 (14%)

Query: 374  EEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT 433
            EE  T HS++T   T SS    T+   E+        G   T      STT   +  +  
Sbjct: 855  EESTTSHSSTT--HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 912

Query: 434  SHPMQ------------------GRTTPSP--EDSSWTDFFNPISHPMGRGHQAGRRMDM 473
            SH  Q                  G +T SP    S  T      +   G   ++      
Sbjct: 913  SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSS 972

Query: 474  DSSHSITLQPTANPNTGLVED--LDRTGPLS--------MTTQQSNSQSFSTSHE--GLE 521
              S + TL P +  ++G+ E+    R+ P S         TT    S+  +TSH   G  
Sbjct: 973  PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 1032

Query: 522  EDKDHPTTSTLTSSNRNDVT----GGRRDPNHSEGSTTLLE-GYTSHYPHTKESRTFIPV 576
            +    P ++T +  ++   T     G  D   S GSTT L  G  S   H+    T   +
Sbjct: 1033 DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 1092

Query: 577  TSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGAN 636
                T S G+      ++++ V+ S    + T  P+  S T+ G + +  +  +     +
Sbjct: 1093 FPDSTTSSGIV-----EASTRVHSSTGSPRTTLSPA--SSTSPGLQGESTAFQTHPASTH 1145

Query: 637  TTSGPIRTPQIP 648
            TT  P  T   P
Sbjct: 1146 TTPSPPSTATAP 1157



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 114/537 (21%), Positives = 193/537 (35%), Gaps = 77/537 (14%)

Query: 122  SAPPEEDCTSVTDLPNAFD-----GPITITIVNRDGTRYVQK-GEYRTNPEDIYPSNPTD 175
            S P +E  TS +  P + D     G  T     ++ T +    G   T    ++P + T 
Sbjct: 2127 SGPSQESTTSHSS-PGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTT---LFPDSTTS 2182

Query: 176  DDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDST--DRIPATTLMSTSATATE 233
              +   S+   SST         +T+ P          +ST     PA+T  + S  +T 
Sbjct: 2183 SGIVEASTRVHSSTGSPR-----TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 2237

Query: 234  TATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFS 293
            TA   + T    S    P+    H   ++  +G S  +      P+         H + S
Sbjct: 2238 TAPVEESTTYHRSPGSTPT---THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 2294

Query: 294  GSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTT 353
            G G        S+T   +P + + T          P  +    L + +T      R+ TT
Sbjct: 2295 GRGE-------STTSRISPGSTEITTL--------PGSTTTPGLSEASTTFYSSPRSPTT 2339

Query: 354  AYEGNWNPEAHPPL-IHHEHHEEEETPHSTSTIQATPSSTT----EETATQKEQWFGNRW 408
                  +P +   L +  E       P ST +  +  S+TT    EE+ T      G+  
Sbjct: 2340 TL----SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 2395

Query: 409  HEGYRQTP----KEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRG 464
               + +TP    + +  +T  +  AS HT+   +  TT    + S     +P S   G  
Sbjct: 2396 TTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGL- 2454

Query: 465  HQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDK 524
                     D     T  P+++ +TG              T  S ++S ++   G    +
Sbjct: 2455 --PATLTTADLGEESTTFPSSSGSTG--------------TTLSPARSTTSGLVG----E 2494

Query: 525  DHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSF 584
              P+  + +S+    + G    P+ SE STT    YTS  P + ++ T  P T+  +G  
Sbjct: 2495 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTF---YTS--PRSPDA-TLSPATTTSSGVS 2548

Query: 585  GVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 641
              ++ +     S    +      T  P    H+T    S G +  +    + TTSGP
Sbjct: 2549 EESSTSHSQPGSTHTTAFPDSTTT--PGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2603



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 81/355 (22%), Positives = 126/355 (35%), Gaps = 65/355 (18%)

Query: 325 TQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYE--GNWNPEAHP-----PLIHHEHHEEEE 377
           T ++   S    L    T  + V    TT++   G  +  A P     P +  E      
Sbjct: 282 TFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHS 341

Query: 378 TPHSTSTIQA----TPSSTTEETAT--------QKEQWFGNRWHEGYRQ--TPKEDS--- 420
            P ST T  +    TPSS   E+ T        +  +   N    G  +  TP   S   
Sbjct: 342 IPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGS 401

Query: 421 -HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSI 479
            H+T   ++++ H   P   ++ PS +D+S          P   G  +       + HS 
Sbjct: 402 PHTTLSPSSSTTHEGEPTTFQSWPSSKDTS----------PAPSGTTSAFVKLSTTYHS- 450

Query: 480 TLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRND 539
              P++ P T            S TT   + +S       +      P   + TS +  +
Sbjct: 451 --SPSSTPTTHF--------SASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEE 500

Query: 540 VTGGRRDPNHSEGSTTLLEGYTSHYP-------HTKESRTFIPVTSAKTGSFGVTAVTVG 592
            T   R P    GST      T H+P       H++ES TF   T+    S    + T  
Sbjct: 501 STAYHRSP----GST-----QTMHFPESSTTSGHSEESATFHGSTTHTKSS--TPSTTAA 549

Query: 593 DSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQI 647
            ++++ + SL G  +T H    S  +  SE    SH S +  A T      TP +
Sbjct: 550 LAHTSYHSSL-GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSV 603



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 108/516 (20%), Positives = 176/516 (34%), Gaps = 84/516 (16%)

Query: 170  PSNPTDD----DVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLM 225
            P +PT       ++S    E S+TS      T STV P     +P +++ +  + +++  
Sbjct: 1251 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA-STTTPGLSEESTTVYSSSRG 1309

Query: 226  STSAT----ATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEE 281
            ST  T    +T T+   +E   + S       +  H    T+ + TS  T  +   P   
Sbjct: 1310 STETTVFPHSTTTSVHGEEPTTFHS-----RPASTHTTLFTEDSTTSGLTEESTAFPGSP 1364

Query: 282  NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTT 341
               +     + + + + ++     S+  +T       +     T      S P  L  ++
Sbjct: 1365 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST---TSGLVGESTPSRLSPSS 1421

Query: 342  TRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPHST-STIQATPSSTTEETAT 398
            T  T +  + TT           P L       +    +P +T S    T S  +EE++T
Sbjct: 1422 TETTTLPGSPTT-----------PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 1470

Query: 399  QKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPIS 458
               Q        G   T      +TT   +    TSH  QG T  +    S T       
Sbjct: 1471 SHSQ-------PGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTT------- 1516

Query: 459  HPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE----DLDRTGPLSMTTQQSNS---- 510
                 G Q+            TL P     +GLVE        TG L  T   ++S    
Sbjct: 1517 -ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1575

Query: 511  -QSFSTSHEGLEEDKD---------------------HPTTSTLTSSNRNDVTGGRRDPN 548
             Q  ST+ +      D                      P+++  T  + +  T GR + +
Sbjct: 1576 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1635

Query: 549  HSEGSTTLLEGYTSHYPHTKESRTFI--PVTS-AKTGSFGVTAVTVGDSNSNVNRSLSGD 605
             +  S+    G T+ +P    +   +  P TS   +GS   TA+      S     LS  
Sbjct: 1636 TTVHSSPGATG-TALFPTRSATSVLVGEPTTSPISSGSTETTAL----PGSTTTAGLSEK 1690

Query: 606  QDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 641
              TF+ S  S  T  S +   S G  E    + S P
Sbjct: 1691 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1726



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 113/486 (23%), Positives = 174/486 (35%), Gaps = 80/486 (16%)

Query: 161 YRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIP 220
           Y  +P      +  +   +SG S E ++  G       ST H          T ST    
Sbjct: 504 YHRSPGSTQTMHFPESSTTSGHSEESATFHG-------STTHTKSS------TPSTTAAL 550

Query: 221 ATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNE 280
           A T   +S  +TET   R       S +   SE     H++     T+   + AG  P+ 
Sbjct: 551 AHTSYHSSLGSTETTHFRDS-----STISGRSEESKASHSSPDAMATT--VLPAGSTPSV 603

Query: 281 ENEDERDRHLSFSGSGIDDDEDFISST----ISTTPRAFDHTKQNQDWTQWNPSHSNPEV 336
              D     +S   SG  +      ST    +S     F  + ++ D T    S ++  V
Sbjct: 604 LVGDSTPSPIS---SGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGV 660

Query: 337 LLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEET 396
             ++TT  +      TTA+ G+       P +  E      +P  T T   +P STT  +
Sbjct: 661 SEESTTSHSRPGSTHTTAFPGSTTM----PGLSQESTASHSSPGPTDTT-LSPGSTTASS 715

Query: 397 ATQKEQWFGNRWHEGYRQTPK-EDSHSTTGTAAASAHT-SHPMQGRTTPSPEDSSWTDFF 454
              +   F +R   G  +T    D+ + +G   AS    S      TT SP  S+     
Sbjct: 716 LGPEYTTFHSR--PGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTT---- 769

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFS 514
                         R+ +  + HS    P++            T P   TT  +  +  +
Sbjct: 770 --------------RQGESTTFHS---WPSSKD----------TRPAPPTTTSAFVEPST 802

Query: 515 TSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFI 574
           TSH         PTT     S  + +       + S GST      T H+P   ES T  
Sbjct: 803 TSHGS---PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ-----TMHFP---ESDTTS 851

Query: 575 PVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSH-TTHGSESDGHSHGSQEG 633
                 T S   T  T+  + S  + +L  +  ++H S GS  TTH  +S   S  S+E 
Sbjct: 852 GRGEESTTSHSSTTHTISSAPSTTS-ALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 910

Query: 634 GANTTS 639
            A+ +S
Sbjct: 911 TASHSS 916


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 122/570 (21%), Positives = 196/570 (34%), Gaps = 101/570 (17%)

Query: 93  PNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSV-TDLPNAFDGPITITIVNRD 151
           P +   A+N     + S T Q  T    +S+PP  +  S+ T  P+    P+T   V+  
Sbjct: 463 PVASSEASNLSTTPVDSKT-QVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTM 521

Query: 152 GTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPW 211
                +     T P D      T  + SS S++   +          S     P E S  
Sbjct: 522 PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGT----------SIPTSTPSEGSTP 571

Query: 212 ITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNT 271
           +T+    +P +T +  S+ A+ T+T              P++S   +  TT    +SS+T
Sbjct: 572 LTN----MPVSTRLVVSSEASTTST-------------TPADSNTFV--TTSSEASSSST 612

Query: 272 ISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSH 331
            + G         ER   ++             +ST+STT                 P  
Sbjct: 613 TAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTT-----------------PVD 655

Query: 332 SNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSS 391
           SN  V   T    +     GT+     +  E   PL     +         ST+  TP  
Sbjct: 656 SNTPVTTSTEATSSSTTAEGTSMPTSTYT-EGSTPLTSMPVNTTLVASSEASTLSTTPVD 714

Query: 392 TTEETATQKEQWFGNRWHEGY---RQTPKEDSHSTTG---------TAAASAHTSHPMQG 439
           T+    T  E        +G      TP E S   T          ++ AS  ++ P+  
Sbjct: 715 TSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDT 774

Query: 440 RT--TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE--DL 495
            T  T S E S         S P+    +    +   +S  +++ P  +P    +    +
Sbjct: 775 STHITTSTEASCSPTTTEGTSMPISTPSEGSPLL---TSIPVSITPVTSPEASTLSTTPV 831

Query: 496 DRTGPLSMTTQQSNSQS--------FSTSHEGLEEDKDHPTTSTL--------------- 532
           D   P++ +T+ S+S +         ST  EG       P ++TL               
Sbjct: 832 DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD 891

Query: 533 TSSNRNDVTGGRRDPNHSEG----STTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTA 588
           TS+   + T  R  P  SEG    ++T  EG T   P T    +  PV S++  +   T 
Sbjct: 892 TSTPVTNSTEARSSPTTSEGTSMPTSTPGEGST---PLTSMPDSTTPVVSSEARTLSATP 948

Query: 589 VTVGDSNSNVNRSLSGDQDTFHPSGGSHTT 618
           V   D+++ V  S           G S  T
Sbjct: 949 V---DTSTPVTTSTEATSSPTTAEGTSIPT 975



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 116/546 (21%), Positives = 186/546 (34%), Gaps = 82/546 (15%)

Query: 86   VVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPE---EDCTSVTDLPNAFDGP 142
            V IP     S    ++    + ++  S   T     S P     E  T +T +P +   P
Sbjct: 3058 VAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTT-P 3116

Query: 143  ITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVH 202
            +T + ++   T  V      T   + + S+PT  + +S  +S  S  S    +   ST+ 
Sbjct: 3117 VTSSAISTLSTTPVDTSTPVTTSTEAH-SSPTTSEGTSMPTSTPSEGSTPLTYMPVSTML 3175

Query: 203  PIPDEDSPW----------ITDSTDRIPATTLMSTSA-TATETATKRQETWDWFSWLFLP 251
             +  EDS            +T ST+   +TT   TS  T+T +      T    S   + 
Sbjct: 3176 VVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVA 3235

Query: 252  SESKNHLHTT---------TQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDED 302
            S   + L TT         T    +SS   + G         E    L+           
Sbjct: 3236 SSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVAS 3295

Query: 303  FISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPE 362
              +ST+STTP        +   T ++ + S+P +             +GT+     ++ E
Sbjct: 3296 SETSTLSTTP-----ADTSTPVTTYSQASSSPPIA------------DGTSMPTSTYS-E 3337

Query: 363  AHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHS 422
               PL +             ST+  TP  T+    T  E        EG        S  
Sbjct: 3338 GSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEG 3397

Query: 423  TTGTAAASAHTSHPMQGR-----TTPSPEDSSWTDFFNPISHP-MGRGHQAGRRMDMDSS 476
            TT  A+    T+  +        TTP   ++  T      S P +  G         + S
Sbjct: 3398 TTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGS 3457

Query: 477  HSITLQP-TANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSS 535
              +++ P +  P          T P+  +T  + S   ++S          PTT+ +TS 
Sbjct: 3458 TPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSS----------PTTAEVTSM 3507

Query: 536  NRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSN 595
              +  T G       EGST          P T    +  PV S++  +   T V   DSN
Sbjct: 3508 PTS--TAG-------EGST----------PLTNMPVSTTPVASSEASTLSTTPV---DSN 3545

Query: 596  SNVNRS 601
            + V  S
Sbjct: 3546 TFVTSS 3551



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 102/499 (20%), Positives = 184/499 (36%), Gaps = 46/499 (9%)

Query: 110  NTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYV--QKGEYRTNPED 167
            +TS   T    AS+ P      V  +  A +G   +T +    T     +     T P D
Sbjct: 2482 DTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVD 2541

Query: 168  IYPSNPTDDDVSSGSSSERSSTSGGYIFYTFST-VHPIPDEDSPWITDSTDRIPATTLMS 226
                  T  ++SS ++S   ++     +   ST +  +P    P  +     + +TT + 
Sbjct: 2542 SNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTL-STTPVD 2600

Query: 227  TS---ATATETATKRQETWDWFSWLFLPSESKNHLHT----TTQMAGTSSNTISAGWEPN 279
            TS    T+TET++      D    +  PSE    L +    T  +A + ++T+S      
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLST----- 2655

Query: 280  EENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQ 339
                D R    + +G+         SS  ++TP        N   +    ++S    L  
Sbjct: 2656 -TPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTL-- 2712

Query: 340  TTTRMTDVDRNGTTAYEGNWNPE-AHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETAT 398
             +T   D     TT+ E + +P  A    +      +  TP ++  +   P +++E +  
Sbjct: 2713 -STTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTV 2771

Query: 399  QKEQWFGNRWHEGYRQTPKEDSHS--TTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNP 456
                            T   D+    TT T A+S+ T+  +    T +P ++S      P
Sbjct: 2772 S---------------TTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMP 2816

Query: 457  ISHPMGRGHQAG--RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQS---NSQ 511
            ++H      +AG      +D+S  +T    A+ +    E +    P+S  ++ S    S 
Sbjct: 2817 VNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGI--VVPISTASEGSTLLTSI 2874

Query: 512  SFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTS-HYPHTKES 570
              ST+     E     TT   TS      T G   P  +EG++  +   +    P T   
Sbjct: 2875 PVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSIL 2934

Query: 571  RTFIPVTSAKTGSFGVTAV 589
             + +PV  ++  +   T V
Sbjct: 2935 VSTVPVAGSEASTLSTTPV 2953



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 102/483 (21%), Positives = 168/483 (34%), Gaps = 76/483 (15%)

Query: 121  ASAPPEEDCTSV-TDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVS 179
            +S PP  + TS+ T  P+    P+T   V+       +     T P D      T   V+
Sbjct: 1021 SSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPAD------TSTPVT 1074

Query: 180  SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQ 239
            + S +  SST+        ST      E S  +T     +P +T +  S+ A+  +T   
Sbjct: 1075 TYSQASSSSTTADGTSMPTSTY----SEGSTPLTS----VPVSTRLVVSSEASTLSTTPV 1126

Query: 240  ETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDD 299
            +T                +  TT    +SS T + G         E    L+        
Sbjct: 1127 DT---------------SIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTL 1171

Query: 300  DEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNW 359
                 ++T+STTP   D   Q    T+     S+P    + T+  T      +T      
Sbjct: 1172 VVSSEANTLSTTP--VDSKTQVATSTE----ASSPPPTAEVTSMPTSTPGERSTPLTSM- 1224

Query: 360  NPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKED 419
             P  H P+   E      +P  TS    TP +T+ ET++                T  E 
Sbjct: 1225 -PVRHTPVASSEASTLSTSPVDTS----TPVTTSAETSSS--------------PTTAEG 1265

Query: 420  SHSTTGTAA--ASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
            +   T T +  ++  TS P+      SPE S  T    P+            +  + +S+
Sbjct: 1266 TSLPTSTTSEGSTLLTSIPVSTTLVTSPEAS--TLLTTPVD----------TKGPVVTSN 1313

Query: 478  SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGL----EEDKDHPTTSTLT 533
             ++  PT    T +       G   +T+   N+   ++S   +      D   P T++  
Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTE 1373

Query: 534  SSNRNDVTGGRRDPNH--SEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTV 591
            + +    + G   PN   SEG+T L     S  P      + +  T   T + G T+   
Sbjct: 1374 ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEA 1433

Query: 592  GDS 594
              S
Sbjct: 1434 TSS 1436



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 53/245 (21%), Positives = 87/245 (35%), Gaps = 15/245 (6%)

Query: 379 PHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQ 438
           P ST  + ++ +STT       + +           T  ED+   T T +  +     M 
Sbjct: 399 PVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMP 458

Query: 439 GRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSS---HSITLQPTANPNTGLVEDL 495
             TTP       ++  N  + P+    Q     +  SS     +   PT+ P+ G    L
Sbjct: 459 VSTTPVAS----SEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGST-PL 513

Query: 496 DRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNH--SEGS 553
                 +M    S + + ST+      D   P T++  +S+ +    G   P    SEGS
Sbjct: 514 TSMSVSTMPVASSEASTLSTT----PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGS 569

Query: 554 TTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSG 613
           T L     S         +    T A + +F VT  +   S+S      S    T+   G
Sbjct: 570 TPLTNMPVSTRLVVSSEASTTSTTPADSNTF-VTTSSEASSSSTTAEGTSMPTSTYSERG 628

Query: 614 GSHTT 618
            + T+
Sbjct: 629 TTITS 633



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 103/494 (20%), Positives = 174/494 (35%), Gaps = 59/494 (11%)

Query: 122  SAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSG 181
            ++ P E  T +  +P +   P+  + VN   T  V      T   +   S+PT   ++ G
Sbjct: 3391 TSSPSEGTTPLASMPVSTT-PVVSSEVNTLSTTPVDSNTLVTTSTEA-SSSPT---IAEG 3445

Query: 182  SSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQET 241
            +S   S+TS G    +   +   P   S   T ST  +  +T ++TS+    + T  + T
Sbjct: 3446 TSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVT 3505

Query: 242  WDWFSWLFLPSESKNHLH-TTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD 300
                S     S    ++  +TT +A + ++T+S    P + N        +F  S     
Sbjct: 3506 SMPTSTAGEGSTPLTNMPVSTTPVASSEASTLST--TPVDSN--------TFVTS----- 3550

Query: 301  EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQT--------TTRMTDVDRNG- 351
                SS  S++P     T           S     +L  T        T     VDR+  
Sbjct: 3551 ----SSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTP 3606

Query: 352  -TTAYEGNWNPEAHPPLIHHEHHEEEETPHSTST-IQATPSSTTEETATQKEQWFGNRWH 409
             TT+ + N  P   PP +         TP   ST +   P STT  T ++          
Sbjct: 3607 VTTSTQSNSTPT--PPEVITL---PMSTPSEVSTPLTIMPVSTTSVTISEA--------- 3652

Query: 410  EGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTP--SPEDSSWTDFFNPISHPMGRGHQA 467
             G   T   D+ +   T+   + +    +G T P  +P + S      P+S       + 
Sbjct: 3653 -GTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSE- 3710

Query: 468  GRRMDMDSSHSITLQPTANPNTGLVEDLDRTG-----PLSMTTQQSNSQSFSTSHEGLEE 522
            G  +   S  + T   T+         LD T      P+ ++T  +     +T      E
Sbjct: 3711 GSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPE 3770

Query: 523  DKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTG 582
                   S  TS +    + G   P   EG+TT+    TS       +    P++     
Sbjct: 3771 SSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPS 3830

Query: 583  SFGVTAVTVGDSNS 596
                 +   GD+++
Sbjct: 3831 EASTLSTPPGDTST 3844



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 87/440 (19%), Positives = 155/440 (35%), Gaps = 47/440 (10%)

Query: 171  SNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITD--STDRIPATTL-MST 227
            + P     +S  S+    ++   I  T  +  PIP E +   T   S  R P T++ +ST
Sbjct: 2111 TTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVST 2170

Query: 228  SATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG---TSSNTISAGWEPNEENED 284
            +  A+   +    T         P ++   +  +T+      TS  T      P+E +  
Sbjct: 2171 TVVASSAISTLSTT---------PVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTP 2221

Query: 285  ERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRM 344
                 +S       +     ++ + T+      T+     T    +      L + TT +
Sbjct: 2222 FTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPL 2281

Query: 345  TDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETA--TQKEQ 402
            T +  + T       +  +  P+       +  TP +TST  ++P  T E T+  T    
Sbjct: 2282 TSIPVSHTLVANSEVSTLSTTPV-------DSNTPFTTSTEASSPPPTAEGTSMPTSTSS 2334

Query: 403  WFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPM----QGRTTPSPED------SSWTD 452
                        T    S  T+  +   A TS P+    Q  ++P+  D      S++++
Sbjct: 2335 EGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSE 2394

Query: 453  FFNPI-SHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQ 511
               P+ S P+             S+HS T   T+ P T   E        S TT +  S 
Sbjct: 2395 GSTPLTSVPVSTMPVVSSEA---STHSTTPVDTSTPVTTSTE-----ASSSPTTAEGTSI 2446

Query: 512  SFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESR 571
              S   EG       P ++T   S+      G       + ST +     +    T    
Sbjct: 2447 PTSPPSEGTTPLASMPVSTTPVVSSE----AGTLSTTPVDTSTPMTTSTEASSSPTTAED 2502

Query: 572  TFIPVTSAKTGSFGVTAVTV 591
              +P+++A  GS  +T++ V
Sbjct: 2503 IVVPISTASEGSTLLTSIPV 2522



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 52/204 (25%), Positives = 73/204 (35%), Gaps = 39/204 (19%)

Query: 413 RQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMD 472
           R TP E    TT  + + + T  P     T SP     TD       PM    +      
Sbjct: 109 RMTPTESR--TTSESTSDSTTLFPSSTEDTSSPTTPEGTDV------PMSTPSEESISST 160

Query: 473 MDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTL 532
           M    +  L P+    T L   +D + PL+ +TQ S+S                PTT   
Sbjct: 161 MAFVSTAPL-PSFEAYTSLTYKVDMSTPLTTSTQASSS----------------PTTPES 203

Query: 533 TSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVG 592
           T+  ++          +SEGST L    TS    T +  +   +T   T     T VT+ 
Sbjct: 204 TTIPKS---------TNSEGSTPL----TSMPASTMKVASSEAITLLTTPVEISTPVTIS 250

Query: 593 DSNSNVNRSLSGDQ-DTFHPSGGS 615
              S+   +  G       PSGGS
Sbjct: 251 AQASSSPTTAEGPSLSNSAPSGGS 274



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 96/413 (23%), Positives = 146/413 (35%), Gaps = 88/413 (21%)

Query: 163  TNPE-DIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDS--PWITDSTDRI 219
            T+PE     + P D +    +S+E SS+             P P E +  P  T S  R 
Sbjct: 819  TSPEASTLSTTPVDSNSPVTTSTEVSSS-------------PTPAEGTSMPTSTYSEGRT 865

Query: 220  P------ATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTIS 273
            P      +TTL++TSA +T + T              P ++   +  +T+    SS T S
Sbjct: 866  PLTSMPVSTTLVATSAISTLSTT--------------PVDTSTPVTNSTE--ARSSPTTS 909

Query: 274  AGWEPNEENEDERDRHLSFSGSGIDDDEDFISS---TISTTPRAFDHTKQNQDWTQWNPS 330
             G         E    L+   S  D     +SS   T+S TP        +   T    +
Sbjct: 910  EGTSMPTSTPGEGSTPLT---SMPDSTTPVVSSEARTLSATP-----VDTSTPVTTSTEA 961

Query: 331  HSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHE------EEETPHSTST 384
             S+P    + T+  T     GTT       P +H  + + E         +  TP +TST
Sbjct: 962  TSSPTTA-EGTSIPTSTPSEGTTPLTST--PVSHTLVANSEASTLSTTPVDSNTPLTTST 1018

Query: 385  IQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPS 444
              ++P  T E T+                 TP E S   T    ++   +       + +
Sbjct: 1019 EASSPPPTAEGTSMP-------------TSTPSEGSTPLTRMPVSTTMVASSETSTLSTT 1065

Query: 445  PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMT 504
            P D+         S P+    QA       SS S T   T+ P +   E       + ++
Sbjct: 1066 PADT---------STPVTTYSQA-------SSSSTTADGTSMPTSTYSEGSTPLTSVPVS 1109

Query: 505  TQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPN-HSEGSTTL 556
            T+   S   ST      +     TTST  SS+     G     +  SEG+T L
Sbjct: 1110 TRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 1162


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 102/472 (21%), Positives = 166/472 (35%), Gaps = 44/472 (9%)

Query: 179  SSGSSSERSSTSGGYIF---YTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETA 235
            ++GS +  +ST G  I     T S       E S   T ST+    T+  +T +  T  +
Sbjct: 707  TTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 236  TKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN---EDERDRHLSF 292
            T   ET    S +   +   + + + T    T+S+ ++  +  N E            + 
Sbjct: 767  TTSSET-TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTV 825

Query: 293  SGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGT 352
            S +G +      + + +TT  + + ++     T+ + + +      +TTT  T      T
Sbjct: 826  STAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 353  TAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTT-EETATQKEQWFGNRWHEG 411
             + EG+                 E T  ST   + T  STT  ET T             
Sbjct: 886  ASTEGSETTTTST-------EGSETTTASTEGSEITTVSTTGSETTTAST---------- 928

Query: 412  YRQTPKEDSHSTTGTAAASAHTSHPMQGRTT--PSPEDSSWTDFFNPISHPMGRGHQAGR 469
                  E S +TT +   S  T+    G  T   S E S  T      S           
Sbjct: 929  ------EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 470  RMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT 529
               + ++ S T   TA+        +  TG  + T   + +++  TS EG E      TT
Sbjct: 983  TTTVSTAGSETT--TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET-----TT 1035

Query: 530  STLTSSNRNDV--TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVT 587
             T   S    V  TG       +EGS T     T     T  +      T + +GS   T
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1095

Query: 588  AVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
            A T G   + V   ++G + T   + GS  T  S +   +  +   G+  T+
Sbjct: 1096 ASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 129/608 (21%), Positives = 195/608 (32%), Gaps = 96/608 (15%)

Query: 98  AANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQ 157
           A + T V    S T+   T     +    ED  + T     F+     T    + T    
Sbjct: 240 AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMAST 298

Query: 158 KGEYRTNPEDIYPSNPTDDDVSS--------GSSSERSSTSGGY---IFYTFSTVHPIPD 206
            G   T    I P        SS        GS + R+ST G     +  T S       
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI 358

Query: 207 EDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAG 266
             S   TDST     TT  +  +  T  +T+  E                   TT    G
Sbjct: 359 MGSETSTDSTTGSETTTASTEGSETTTASTEGSEA------------------TTVSTTG 400

Query: 267 TSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQ 326
           + + T+S          D         GS +        + +STT   F+ T  + + ++
Sbjct: 401 SETTTVSI--------TDSETTTTCTEGSEM--------TAVSTT--VFETTTASTEGSE 442

Query: 327 WNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQ 386
              + ++     +TTT  T+     T    G+    A+      E      T   T+T+ 
Sbjct: 443 ITIASTSDS---ETTTASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGLETTTVF 497

Query: 387 ATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPS 444
              S TT  +    E    +           E S +TT +   S  T+    G   TT S
Sbjct: 498 TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTS 557

Query: 445 PEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLD-------- 496
            E S  T               A    D       T   TA   T  V   D        
Sbjct: 558 TEGSEMTTVSTT---------GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 497 ---------RTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDP 547
                     TG  + T   ++S++ + S EG E      T S  T  +    TG  R  
Sbjct: 609 ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS---TTGSERTI 665

Query: 548 NHSEGS-TTLLEGYTSHYPHTKE--SRTFIPVTSAKTGSFGV----TAVTVGDSNSNVNR 600
             +EGS TT +    S    + E    T + +T ++T         T +T  + +     
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTA 725

Query: 601 SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL 660
           S++G + T   + GS TT  S     + GS+   A+TT     T         +AS++  
Sbjct: 726 SITGSETTTASTEGSETTTAS-----TEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 661 ALILAVCI 668
              +A  I
Sbjct: 781 ETTMASTI 788



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 115/513 (22%), Positives = 170/513 (33%), Gaps = 77/513 (15%)

Query: 144  TITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHP 203
            TI       T  V      T P     S  T    + GS +  +ST G            
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS----------- 861

Query: 204  IPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQ 263
               E +   T+S++   ATT+ S + TA+   ++   T    S     S   + +   T 
Sbjct: 862  ---ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI---TT 915

Query: 264  MAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQD 323
            ++ T S T +A  E +E          S  GS +       S TI+ +    + T     
Sbjct: 916  VSTTGSETTTASTEGSETTT------ASTEGSELTTVSTTGSETITVSAEGSETTTVT-- 967

Query: 324  WTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTS 383
             T  + + +      +TTT  T      T + EG+                       T+
Sbjct: 968  -TMGSETTTASTAGSETTTVSTAGSETTTASIEGS----------------------ETT 1004

Query: 384  TIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGR--T 441
            T+ +T S TT  + T  E             T  E S +TT T A S  T+    G   T
Sbjct: 1005 TVSSTGSETTTVSTTGTETTI----------TSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 442  TPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHS-ITLQPTANPNTGLV-------E 493
            T S E S  T      S              + +S S  T   TA   T  V        
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 494  DLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGS 553
                 G  + T   ++S++ + S  G E      T S  T+ +             SE +
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 554  TTLLEGYTSHYPHTKESRTFIP-------VTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQ 606
            TT  EG  +    T  S T           T++ +GS   TA T G   S  + + S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 607  DTFHPSGGSHTTHGSESDGHSHGSQEGGANTTS 639
              F    GS TT  S +      +   G+ TT+
Sbjct: 1235 TAF--IIGSETTIASTASLEPTATSLTGSETTT 1265



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 120/556 (21%), Positives = 193/556 (34%), Gaps = 60/556 (10%)

Query: 109 SNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDI 168
           S TS   T    A +      T  ++   A+      T  +  G+       +    E I
Sbjct: 128 STTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV--FTAGSETI 185

Query: 169 YPSNPTDDDVS---SGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPA---T 222
            PS    +  +   +GS +   ST+G     T ST H      S   +++T    A   T
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETT-TASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 223 TLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEEN 282
           T+ +  +  T  +T+  ET   F+      +SK    +TT    T+++T   G EP   +
Sbjct: 245 TVSTAGSETTAASTEDSETNTAFT-----EDSKTTTASTTGFETTAAST--TGSEPTMAS 297

Query: 283 EDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQ----NQDWTQWNPSHSNPEVLL 338
               +  ++ +           SS ++T   A   T +      + T  + + S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 339 ----QTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTE 394
               +T+T  T      T + EG+    A           E  T  +T +   T S T  
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETTTAST------EGSEATTVSTTGSETTTVSITDS 411

Query: 395 ETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFF 454
           ET T   +  G+          +  + ST G+    A TS      TT S E S  T   
Sbjct: 412 ETTTTCTE--GSEMTAVSTTVFETTTASTEGSEITIASTSD--SETTTASTEGSETTTVT 467

Query: 455 NPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRT-GPLSMTTQQSNSQSF 513
              S             +  ++++   + T   NTGL      T G  + T     S++ 
Sbjct: 468 TAGS-------------ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 514 STSHEGLE------EDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
           + S  G E      E  ++ T ST  S      T G      S   + +    T+    T
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETT 574

Query: 568 KESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHS 627
            +S      T+A T     T V+  DS  N   S +  + T   + GS TT  S +   +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSE-NTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 628 -----HGSQEGGANTT 638
                 GS+    +TT
Sbjct: 634 TTASTEGSETTTVSTT 649



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 100/476 (21%), Positives = 165/476 (34%), Gaps = 88/476 (18%)

Query: 179 SSGSSSERSSTSGGYIFYTFS----TVHPIPDEDSPWITDSTDRIPATTLMSTSATATET 234
           ++ S +  +ST+G  +   F+    T+ P     S   T ST     TT+ +T +  T  
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITP-STAGSETTTVSTAGSETTTVSTTGSETTTA 217

Query: 235 ATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSG 294
           +T   ET          + +     T    AG+ +   +AG E    + ++ + + +F+ 
Sbjct: 218 STAHSET--------TAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT- 268

Query: 295 SGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWN-PSHSNPEVLLQTT-----TRMTDVD 348
                 ED  ++T STT   F+ T  +   ++    S    E  + +T     T+++   
Sbjct: 269 ------EDSKTTTASTT--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 320

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRW 408
              TT +               E          T+T+  T S TT  +    E       
Sbjct: 321 SEVTTVFAAG-----------SETIRASTVGSETTTVSTTGSETTTASIMGSET------ 363

Query: 409 HEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAG 468
                      + STTG+   +A T       TT S E S  T                 
Sbjct: 364 ----------STDSTTGSETTTASTEG--SETTTASTEGSEATT---------------- 395

Query: 469 RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPT 528
             +    S + T+  T +  T    +      +S T  ++ + S   S   +    D  T
Sbjct: 396 --VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 529 TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVT 587
           T+  T  +             + GS T    YT+    T  S T +  T+  T GS   T
Sbjct: 454 TTASTEGSETTTVT-------TAGSETKT-AYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 588 AVTVGDSNSNVNRSLSGDQDTFHPSGGSHT---THGSESDGHSHGSQEGGANTTSG 640
           A T G   + V+ + S +  T    G  +T   T GSE+   S    E    +T G
Sbjct: 506 ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEG 560



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 12/222 (5%)

Query: 420 SHSTTGTAAASAHTSHPMQGR--TTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
           S +TT    AS  T+    G   TTPSP  S  T      S              + S+ 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 478 SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
           S T   T     G    +   G  + T   + +++   S  G E   +  T+S  T ++ 
Sbjct: 83  SGT---TTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTS- 138

Query: 538 NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKT-GSFGVTAVTVGDSNS 596
              T G      S   +     YT+    T  S T   +T+  T GS  +T  T G   +
Sbjct: 139 ---TAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195

Query: 597 NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTT 638
            V+ + S +  T   +G S TT  S +   +  +   G+ TT
Sbjct: 196 TVSTAGS-ETTTVSTTG-SETTTASTAHSETTAASTMGSETT 235


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 128/573 (22%), Positives = 201/573 (35%), Gaps = 92/573 (16%)

Query: 136  PNAFDGPITIT---IVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSS---- 188
            P+A   P T T   +     T + Q G   T     +P + T  D+S   ++  SS    
Sbjct: 937  PDATLSPATTTSSGVSEESSTSHSQPGSTHTTA---FPDSTTTSDLSQEPTTSHSSQGST 993

Query: 189  --------TSGGYIFYTFSTVHPIP-DEDSPWITDST---DRIPATT--------LMSTS 228
                    T+   +    +T H  P D ++  + D T     + A+T        L +T 
Sbjct: 994  EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1053

Query: 229  ATATETATKRQETWDWF-SWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERD 287
              A+ T+   QE    F SW   PS S     TT    GT++  +      +        
Sbjct: 1054 TPASSTSAGLQEESTTFQSW---PSSSD----TTPSPPGTTAAPVEVSTTYHSRPSSTPT 1106

Query: 288  RHLSFSGSGIDDDEDFISSTISTTP----------RAFDHTKQNQDWTQWNPSHSNPEVL 337
             H S S + +   E+  S+T+ ++P          R+       +  T    S S     
Sbjct: 1107 THFSASSTTLGRSEE--STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 1164

Query: 338  LQTTTRMTDVDRNGTTAYEGNWNPEA--HPPLIHHEHHEEEET-----PHSTSTIQATPS 390
            L  +T    +    TT Y    +P+    P         EE T     P ST T  A P 
Sbjct: 1165 LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTT-AFPG 1223

Query: 391  STTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQG--RTTPSPEDS 448
            STT    +Q+     +    G   T      +T  +    + T H   G   TT  P+++
Sbjct: 1224 STTMPGVSQEST--ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNT 1281

Query: 449  SWTDFFN---PISHPMGRGHQ----AGRRMDMDSSHSITLQPTANPN-------TGLVED 494
            + +       P+    G  H     AG       S +    P++          T    +
Sbjct: 1282 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1341

Query: 495  LDRTGPLSMTTQQSNSQSFSTSHEGLEEDK----DHPTTSTLTSSNRNDVTGGRRDPN-- 548
            L  T   S ++  +   S S++  G  E+       P  +  T S     T G  + +  
Sbjct: 1342 LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTA 1401

Query: 549  -HSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQD 607
             HS   +T     T H+P   ES T    +     S   T  T+    S  + +L  +  
Sbjct: 1402 YHSSPGST----QTMHFP---ESSTASGRSEESRTSHSSTTHTISSPPSTTS-ALVEEPT 1453

Query: 608  TFHPSGGS-HTTHGSESDGHSHGSQEGGANTTS 639
            ++H S GS  TTH  ES   S  S+E  A+ +S
Sbjct: 1454 SYHSSPGSIATTHFPESSTTSGRSEESTASHSS 1486



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 101/416 (24%), Positives = 152/416 (36%), Gaps = 57/416 (13%)

Query: 174 TDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATAT- 232
           T   +SSGS  E ++  G       ST  P   E S     S+ R PATTL   S T++ 
Sbjct: 426 TTSPISSGSM-ETTALPG-------STTTPGLSERSTTF-HSSPRSPATTLSPASTTSSG 476

Query: 233 ---ETATKRQETWDWFSWLFLPSESKNHL--HTTTQMAGTSSNTISAGWEPNEENEDERD 287
              E+ T R       +  F  S +   L  H+TT  +   S   +        +   ++
Sbjct: 477 VSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE 536

Query: 288 RHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNP----EVLLQTTTR 343
              S S SG     D   S  STT  +F      Q+ T +   HSNP      L   +T 
Sbjct: 537 STTSHSSSG---STDTALSPGSTTALSF-----GQESTTF---HSNPGSTHTTLFPDSTT 585

Query: 344 MTDVDRNGTTAYEGNWNPE-------AHPPLIHHEHHEEEETPHSTSTIQATPSSTT--- 393
            + +    T  +    +P        +  P +  E    +  P ST T  + PS+ T   
Sbjct: 586 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 645

Query: 394 EETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDF 453
           EE+ T         +H     TP      TT   A+S  + H  +     S  D+S T  
Sbjct: 646 EESTT---------YHRSPGSTP------TTHFPASSTTSGHSEKSTIFHSSPDASGTTP 690

Query: 454 FNPISHPMGRGHQAGRRMDMDSSHSITLQ-PTANPNTGLVEDLDRTGPLSMTTQQSNSQS 512
            +  S   GRG     R+   S+   TL   T  P          + P S TT  S +  
Sbjct: 691 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 750

Query: 513 FSTS-HEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHT 567
            S    E     +  P ++  T S  +  T G  + + +  S++     T+ +PH+
Sbjct: 751 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHS 806



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 72/312 (23%), Positives = 113/312 (36%), Gaps = 46/312 (14%)

Query: 374 EEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHT 433
           EE  T HS++T   T SS    T+   E+        G   T      STT   +  +  
Sbjct: 342 EESTTSHSSTT--HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 399

Query: 434 SHPMQ------------------GRTTPSP--EDSSWTDFFNPISHPMGRGHQAGRRMDM 473
           SH  Q                  G +T SP    S  T      +   G   ++      
Sbjct: 400 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSS 459

Query: 474 DSSHSITLQPTANPNTGLVED--LDRTGPLS--------MTTQQSNSQSFSTSHE--GLE 521
             S + TL P +  ++G+ E+    R+ P S         TT    S+  +TSH   G  
Sbjct: 460 PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 519

Query: 522 EDKDHPTTSTLTSSNRNDVT----GGRRDPNHSEGSTTLLE-GYTSHYPHTKESRTFIPV 576
           +    P ++T +  ++   T     G  D   S GSTT L  G  S   H+    T   +
Sbjct: 520 DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL 579

Query: 577 TSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGAN 636
               T S G+      ++++ V+ S    + T  P+  S T+ G + +  +  +     +
Sbjct: 580 FPDSTTSSGIV-----EASTRVHSSTGSPRTTLSPA--SSTSPGLQGESTAFQTHPASTH 632

Query: 637 TTSGPIRTPQIP 648
           TT  P  T   P
Sbjct: 633 TTPSPPSTATAP 644



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 104/526 (19%), Positives = 179/526 (34%), Gaps = 79/526 (15%)

Query: 157  QKGEYRTNPEDIYPSNPTDDDVSSG----SSSERSSTSGGYIFYT--FSTVHPIPDEDS- 209
            Q   + ++P D   +   DD ++SG    S+   SST   +   T   ST   + +E + 
Sbjct: 1010 QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTT 1069

Query: 210  ----PWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLP---SESKNHLHTTT 262
                P  +D+T   P TT      + T  +         FS        SE    +H++ 
Sbjct: 1070 FQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 1129

Query: 263  QMAGT------SSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFD 316
               GT      S+ ++  G               +  GS         S+T  ++PR+ D
Sbjct: 1130 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD 1189

Query: 317  HTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEE 376
             T      T    S        ++TT  +      TTA+ G+       P +  E     
Sbjct: 1190 TTLSPASTTSSGVSE-------ESTTSHSRPGSTHTTAFPGSTTM----PGVSQESTASH 1238

Query: 377  ETPHSTSTIQATPSSTTEETATQKEQWFGN--------------------------RWHE 410
             +P ST T   +P STT  +   +   F +                              
Sbjct: 1239 SSPGSTDTT-LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSST 1297

Query: 411  GYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPE-----------------DSSWTDF 453
            G   T    + STT    ++   S P    T P+P                   S+ T  
Sbjct: 1298 GSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTH 1357

Query: 454  FNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSF 513
            F+  S  +GR  ++        + + T  P  +  +GLVE+         +TQ  +    
Sbjct: 1358 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPES 1417

Query: 514  STSHEGLEEDK-DHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRT 572
            ST+    EE +  H +T+   SS  +  +    +P     S   +   T+H+P +  +  
Sbjct: 1418 STASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIA--TTHFPESSTTSG 1475

Query: 573  FIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTT 618
                ++A   S     +T   ++   +  ++ +  TF+ S GS  T
Sbjct: 1476 RSEESTASHSSPDTNGITPLPAHFTTSGRIA-ESTTFYISPGSMET 1520



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 108/516 (20%), Positives = 176/516 (34%), Gaps = 84/516 (16%)

Query: 170  PSNPTDD----DVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLM 225
            P +PT       ++S    E S+TS      T STV P     +P +++ +  + +++  
Sbjct: 738  PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA-STTTPGLSEESTTVYSSSRG 796

Query: 226  STSAT----ATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEE 281
            ST  T    +T T+   +E   + S       +  H    T+ + TS  T  +   P   
Sbjct: 797  STETTVFPHSTTTSVHGEEPTTFHS-----RPASTHTTLFTEDSTTSGLTEESTAFPGSP 851

Query: 282  NEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTT 341
               +     + + + + ++     S+  +T       +     T      S P  L  ++
Sbjct: 852  ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST---TSGLVGESTPSRLSPSS 908

Query: 342  TRMTDVDRNGTTAYEGNWNPEAHPPLIHHE--HHEEEETPHST-STIQATPSSTTEETAT 398
            T  T +  + TT           P L       +    +P +T S    T S  +EE++T
Sbjct: 909  TETTTLPGSPTT-----------PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 957

Query: 399  QKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPIS 458
               Q        G   T      +TT   +    TSH  QG T  +    S T       
Sbjct: 958  SHSQ-------PGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTT------- 1003

Query: 459  HPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVE----DLDRTGPLSMTTQQSNS---- 510
                 G Q+            TL P     +GLVE        TG L  T   ++S    
Sbjct: 1004 -ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1062

Query: 511  -QSFSTSHEGLEEDKD---------------------HPTTSTLTSSNRNDVTGGRRDPN 548
             Q  ST+ +      D                      P+++  T  + +  T GR + +
Sbjct: 1063 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1122

Query: 549  HSEGSTTLLEGYTSHYPHTKESRTFI--PVTS-AKTGSFGVTAVTVGDSNSNVNRSLSGD 605
             +  S+    G T+ +P    +   +  P TS   +GS   TA+      S     LS  
Sbjct: 1123 TTVHSSPGATG-TALFPTRSATSVLVGEPTTSPISSGSTETTAL----PGSTTTAGLSEK 1177

Query: 606  QDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGP 641
              TF+ S  S  T  S +   S G  E    + S P
Sbjct: 1178 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1213



 Score = 36.6 bits (83), Expect = 0.087
 Identities = 110/468 (23%), Positives = 170/468 (36%), Gaps = 79/468 (16%)

Query: 179 SSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKR 238
           ++   SE S+T  G   +T S+            T ST    A T   +S  +TET   R
Sbjct: 8   TTSGHSEESATFHGSTTHTKSS------------TPSTTAALAHTSYHSSLGSTETTHFR 55

Query: 239 QETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGID 298
                  S +   SE     H++     T+   + AG  P+    D     +S   SG  
Sbjct: 56  DS-----STISGRSEESKASHSSPDAMATT--VLPAGSTPSVLVGDSTPSPIS---SGSM 105

Query: 299 DDEDFISST----ISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTA 354
           +      ST    +S     F  + ++ D T    S ++  V  ++TT  +      TTA
Sbjct: 106 ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA 165

Query: 355 YEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQ 414
           + G+       P +  E      +P  T T   +P STT  +   +   F +R   G  +
Sbjct: 166 FPGSTTM----PGLSQESTASHSSPGPTDTT-LSPGSTTASSLGPEYTTFHSR--PGSTE 218

Query: 415 TPK-EDSHSTTGTAAASAHT-SHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMD 472
           T    D+ + +G   AS    S      TT SP  S+                   R+ +
Sbjct: 219 TTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTT------------------RQGE 260

Query: 473 MDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTL 532
             + HS    P++            T P   TT  +  +  +TSH         PTT   
Sbjct: 261 STTFHS---WPSSKD----------TRPAPPTTTSAFVEPSTTSHGS---PSSIPTTHIS 304

Query: 533 TSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVG 592
             S  + +       + S GST      T H+P   ES T        T S   T  T+ 
Sbjct: 305 ARSTTSGLVEESTTYHSSPGSTQ-----TMHFP---ESDTTSGRGEESTTSHSSTTHTIS 356

Query: 593 DSNSNVNRSLSGDQDTFHPSGGSH-TTHGSESDGHSHGSQEGGANTTS 639
            + S  + +L  +  ++H S GS  TTH  +S   S  S+E  A+ +S
Sbjct: 357 SAPSTTS-ALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 403


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 113/538 (21%), Positives = 175/538 (32%), Gaps = 72/538 (13%)

Query: 171 SNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSAT 230
           S+ T   VS+ + S  S TS G    T S  H          T S       +  ST ++
Sbjct: 50  SSVTSSGVSTATISGSSVTSNGVSIVTNSEFHT---------TSSGISTATNSEFSTVSS 100

Query: 231 ATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHL 290
               AT  + +                  TT+  A T++N+ S+            D   
Sbjct: 101 GISIATNSESS------------------TTSSGASTATNSESSTPSSGASTATNSDSST 142

Query: 291 SFSGSGI--DDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVD 348
           + SG+    + D    SS  ST   +   T  +   T  N   S       T T      
Sbjct: 143 TSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESST 202

Query: 349 RNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEE---TATQKEQWFG 405
            +   +   N               E   T +   T   + SSTT     TAT  E    
Sbjct: 203 TSSGASTATN--------------SESRTTSNGAGTATNSESSTTSSGASTATNSESSTP 248

Query: 406 NRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGH 465
           +        +    + S  GTA  S  ++      T  + E S+ +   N  ++      
Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308

Query: 466 QAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKD 525
            +G     +S  S T   ++  +T    +   T   + T   S S + S+          
Sbjct: 309 SSGANTATNSDSSTT---SSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGS 365

Query: 526 HPT---TSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTG 582
             T   TST T+S  + V+ G      SE STT     T+      ES T     S  T 
Sbjct: 366 STTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTA---TNSESSTVSSGASTATN 422

Query: 583 SFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPI 642
           S   T  +  ++ +N   S++          G HTT  S S   S     G         
Sbjct: 423 SESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGG--------- 473

Query: 643 RTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLN 700
               +  W I L +L+++   + +   +     C +    + N+ N AV    P GLN
Sbjct: 474 ---SLVPWEIFLITLVSVVAAVGLFAGLFF---CVRNSLSLRNTFNTAV--YHPHGLN 523



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 63/272 (23%), Positives = 104/272 (38%), Gaps = 34/272 (12%)

Query: 372 HHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASA 431
           H E     + TST   T SS     A+          + G   T    S  +T T + S+
Sbjct: 17  HLEAATNSNETSTSANTGSSVISSGASTAT-------NSGSSVT---SSGVSTATISGSS 66

Query: 432 HTSHPM------QGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTA 485
            TS+ +      +  TT S   ++    F+ +S  +     +        + + T   ++
Sbjct: 67  VTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESS 126

Query: 486 NPNTGL--VEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTT-----STLTSSNRN 538
            P++G     + D +   S  +  +NS S +TS E         +T     ST T+S  +
Sbjct: 127 TPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESS 186

Query: 539 DVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNV 598
            V+       +SE STT     T+      ESRT        T +   TA     S ++ 
Sbjct: 187 TVSSRASTATNSESSTTSSGASTAT---NSESRT--------TSNGAGTATNSESSTTSS 235

Query: 599 NRSLSGDQDTFHPSGGSHTTHGSESDGHSHGS 630
             S + + ++  PS G+ T   SES   S G+
Sbjct: 236 GASTATNSESSTPSSGAGTATNSESSTTSSGA 267


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 70/313 (22%), Positives = 107/313 (34%), Gaps = 45/313 (14%)

Query: 345  TDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHST-STIQATPSSTTE-------ET 396
            ++V   G+  + G+ + +A       +H E E T H    T       TTE       +T
Sbjct: 1886 SEVHSGGSHTHSGHTHSQARS-----QHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQT 1940

Query: 397  ATQKEQWFGNRW--HEGYRQT--PKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTD 452
                 +  G R   H  Y  +  P   SH+ +G     A + +P  G +      ++   
Sbjct: 1941 IQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQ 2000

Query: 453  FFNPISHP-MGRGHQA-------GRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMT 504
              +   H   G G          GRR    S +S +   +   +T       + G     
Sbjct: 2001 TADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGE 2060

Query: 505  TQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHY 564
            +  S  +   T+H    +   H  +    S+ R   T GRR   HSE S + +    S  
Sbjct: 2061 SGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVS-- 2118

Query: 565  PHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESD 624
             HT    T           +G      G+S S    ++ G Q T H   G  T HG    
Sbjct: 2119 -HTHSGHT-----------YGQARSQHGESGS----AIHGRQGTIHGQTGDTTRHG--QS 2160

Query: 625  GHSHGSQEGGANT 637
            GH   +Q G   T
Sbjct: 2161 GHGQSTQTGSRTT 2173



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 72/300 (24%), Positives = 107/300 (35%), Gaps = 45/300 (15%)

Query: 373  HEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAH 432
            H  +ET H  +      S + +  +TQ     G+R     R +  E+S S   +  +  H
Sbjct: 1233 HGRQETTHGQTINTTRHSQSGQGQSTQT----GSRVTRRRRSSQSENSDSEVHSKVSHRH 1288

Query: 433  TSH---------PMQGRTTPSPEDSSWTDFFNPISHPM---GRGHQAGRRMDMDSSHSIT 480
            + H         P  G T    + ++     +   H     G+  Q G R       S +
Sbjct: 1289 SEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHS 1348

Query: 481  LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQ---SFSTSHEGLE-------EDKDHPTTS 530
                +  ++G+     R      T  Q+ SQ   S ST HE  E       E   H  + 
Sbjct: 1349 DATDSEVHSGVSH---RPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSG 1405

Query: 531  TLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS-FGVTAV 589
               S+ R   T GRR   HSE S + +    SH P ++E       T  + GS  G +  
Sbjct: 1406 HGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQ------THGQAGSQHGESGS 1459

Query: 590  TVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSES-----DGHSHGS----QEGGANTTSG 640
            TV   +   +          H   G  T  GS +      GHS  S      GG++T SG
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSG 1519



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 66/255 (25%), Positives = 85/255 (33%), Gaps = 41/255 (16%)

Query: 421  HSTTGTAAASAHTSHPMQGRT---TPSPEDSSWTDFFNPISH------PMGRGH---QAG 468
            H  TG     AH+ H    +T   T     S  +++ +   H      P  RGH   QAG
Sbjct: 1771 HGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAG 1830

Query: 469  RRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHP- 527
             +     S       T +  TG      ++G    T  QS S +      G  E  D   
Sbjct: 1831 SQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQST--QSGSSTTGRRRSGHSESSDSEV 1888

Query: 528  ------TTSTLTSSNRNDVTGGRRDPNHSEGSTTLLE-GYTSHYPHTKESRTFIPVTSAK 580
                  T S  T S      G      H    TT  + G T+ + H    +T I   S  
Sbjct: 1889 HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQT-IQTGSRT 1947

Query: 581  TGSFGVTAVTVGDSN--SNVNRSLSGDQDTFHPSGGSH-------------TTHGSESDG 625
            TG  G       DS   S V+ + SG     H   GSH             TTHG  +D 
Sbjct: 1948 TGRRGSGHSEYSDSEGPSGVSHTHSGHT---HGQAGSHYPESGSSVHERHGTTHGQTADT 2004

Query: 626  HSHGSQEGGANTTSG 640
              HG    G +T  G
Sbjct: 2005 TRHGHSGHGQSTQRG 2019



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 88/415 (21%), Positives = 138/415 (33%), Gaps = 70/415 (16%)

Query: 252  SESKNH-LHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTIST 310
            SES  H  H TT   G +      G   + ++     R     GSG  +  D      S 
Sbjct: 1380 SESTVHERHETTY--GQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSD------SE 1431

Query: 311  TPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTT-AYEGNWNPEAHPPLIH 369
                  H  Q+Q+ T       + E      +  T   R+GTT    G+    AH     
Sbjct: 1432 VHSGGSHRPQSQEQTHGQAGSQHGE------SGSTVHGRHGTTHGQTGDTTRHAH----- 1480

Query: 370  HEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAA 429
              +H  + T   +ST     S  +E + ++     G+  H G+        H  + +   
Sbjct: 1481 --YHHGKSTQRGSSTTGRRGSGHSESSDSEVHSG-GSHTHSGHTHGQSGSQHGESESIIH 1537

Query: 430  SAHT-SHPMQGRTT----PSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPT 484
              H  +H   G TT       E ++ T                   +    SH    +P 
Sbjct: 1538 DRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSH----RPH 1593

Query: 485  ANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGR 544
            +  +T       + G      + +  +   T+H  + +   H  +    S+ R   T GR
Sbjct: 1594 SREHT-----YGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGR 1648

Query: 545  RDPNHSEGSTTLLEGYTSHYPHT-----------KESRTFIP----VTSAKTGS------ 583
            +  +HSE S + +    SH  HT            +S + +P     T  +TG       
Sbjct: 1649 QRSSHSESSDSEVHSGVSH-THTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAH 1707

Query: 584  --FGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHG---SQEG 633
               G+T  T   +        S   D+   SG SHT       GH+HG   SQ G
Sbjct: 1708 YHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHT-----HSGHTHGQARSQHG 1757



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 57/281 (20%), Positives = 97/281 (34%), Gaps = 19/281 (6%)

Query: 370  HEHHEE------EETPHSTSTI-QATP--SSTTEETATQKEQWFGNRWHEG--YRQTPKE 418
            HE HE       E T H  S   Q+T   S TT    +   +   +  H G  +R   +E
Sbjct: 1385 HERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQE 1444

Query: 419  DSHSTTGTA-AASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
             +H   G+    S  T H   G T     D++    ++            GRR    S  
Sbjct: 1445 QTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSES 1504

Query: 478  SITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNR 537
            S +   +   +T       ++G     ++         +H    +   H  +    ++  
Sbjct: 1505 SDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQT 1564

Query: 538  NDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS-FGVTAVTVGDSNS 596
               T GR+  +HSE + + +    SH PH++E       T  + GS       TV + + 
Sbjct: 1565 GSRTTGRQRTSHSESTDSEVHSGGSHRPHSREH------TYGQAGSQHEEPEFTVHERHG 1618

Query: 597  NVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANT 637
              +  +       H   G  T  GS + G    S    +++
Sbjct: 1619 TTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDS 1659



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 99/457 (21%), Positives = 140/457 (30%), Gaps = 83/457 (18%)

Query: 252  SESKNHL-HTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTIST 310
            SES  H  H TT   G + +T   G   + +      R     GSG  +  D      S 
Sbjct: 1911 SESTVHKRHQTTH--GQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSD------SE 1962

Query: 311  TPRAFDHTKQN----QDWTQWNPSHSNPEVLLQTTTRMT-DVDRNGTTAYEGNWNPEAHP 365
             P    HT       Q  + +  S S+      TT   T D  R+G + +  +    +  
Sbjct: 1963 GPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRT 2022

Query: 366  PLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTG 425
                   H E       S +  T S      A  +    G+  HE +  T     H  TG
Sbjct: 2023 TGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTT-----HGQTG 2077

Query: 426  TAAASAHTSHPMQ--------GRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSH 477
                 AH+ H           GR      +SS ++  + +SH    GH  G+        
Sbjct: 2078 DTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHS-GHTYGQARSQHGES 2136

Query: 478  SITLQPTANPNTGLVEDLDRTGPL---------SMTTQQSNSQSFSTSHEGLEEDKDHPT 528
               +        G   D  R G           S TT +  S S S S +     +  PT
Sbjct: 2137 GSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRS-SHSESSDSEVHSEASPT 2195

Query: 529  TSTLT---------------------------------------SSNRNDVTGGRRDPNH 549
             S  T                                       S+ R   T GRR   H
Sbjct: 2196 HSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGH 2255

Query: 550  SEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGS--FGVTAVTVGDSNSNVNRSLSG-DQ 606
            SE S + +  + SH  H+   +        + GS   G    T G +        SG  Q
Sbjct: 2256 SESSDSEVHSWGSH-THSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQ 2314

Query: 607  DTFHPSGGSHTTH--GSESDGHSHGSQEGGANTTSGP 641
             T   S  S  +H     S+   HGS +   + + GP
Sbjct: 2315 STQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGP 2351


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,271,547
Number of Sequences: 37866
Number of extensions: 1528498
Number of successful extensions: 5124
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 4555
Number of HSP's gapped (non-prelim): 453
length of query: 742
length of database: 18,247,518
effective HSP length: 110
effective length of query: 632
effective length of database: 14,082,258
effective search space: 8899987056
effective search space used: 8899987056
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press