Guide to the Human Genome
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Search of human proteins with 48255929

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48255929 periphilin 1 isoform 1 [Homo sapiens]
         (458 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48255929 periphilin 1 isoform 1 [Homo sapiens]                     937   0.0  
gi|219842244 periphilin 1 isoform 6 [Homo sapiens]                    752   0.0  
gi|41872344 periphilin 1 isoform 3 [Homo sapiens]                     697   0.0  
gi|41872368 periphilin 1 isoform 2 [Homo sapiens]                     697   0.0  
gi|219842247 periphilin 1 isoform 7 [Homo sapiens]                    645   0.0  
gi|41872349 periphilin 1 isoform 4 [Homo sapiens]                     528   e-150
gi|219842250 periphilin 1 isoform 8 [Homo sapiens]                    476   e-134
gi|41872339 periphilin 1 isoform 5 [Homo sapiens]                     455   e-128
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          52   1e-06
gi|50083281 KIAA1853 protein [Homo sapiens]                            47   4e-05
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    47   5e-05
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    47   5e-05
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]    47   5e-05
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     45   1e-04
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  45   1e-04
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    45   1e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    45   2e-04
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     44   2e-04
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]     44   2e-04
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...    44   2e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     44   3e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   3e-04
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     44   3e-04
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    42   9e-04
gi|229577273 BUD13 homolog isoform 2 [Homo sapiens]                    42   0.001
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             42   0.002
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             42   0.002
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             42   0.002
gi|221139764 PHD and ring finger domains 1 [Homo sapiens]              41   0.002
gi|62526045 zinc finger protein 638 [Homo sapiens]                     41   0.002

>gi|48255929 periphilin 1 isoform 1 [Homo sapiens]
          Length = 458

 Score =  937 bits (2421), Expect = 0.0
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK
Sbjct: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180

Query: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240
           RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK
Sbjct: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240

Query: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300
           LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE
Sbjct: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300

Query: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMD 360
           IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMD
Sbjct: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMD 360

Query: 361 HDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDITWGMLKKTTQEA 420
           HDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDITWGMLKKTTQEA
Sbjct: 361 HDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDITWGMLKKTTQEA 420

Query: 421 ERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENKQ 458
           ERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENKQ
Sbjct: 421 ERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENKQ 458


>gi|219842244 periphilin 1 isoform 6 [Homo sapiens]
          Length = 434

 Score =  752 bits (1941), Expect = 0.0
 Identities = 383/421 (90%), Positives = 383/421 (90%), Gaps = 33/421 (7%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 14  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 73

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 188
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE
Sbjct: 74  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 133

Query: 189 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 248
           RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 134 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 193

Query: 249 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 308
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD
Sbjct: 194 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 253

Query: 309 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMDHDGTPENE 368
           CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMDHDGTPENE
Sbjct: 254 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMDHDGTPENE 313

Query: 369 GEETAQS-------------------------------APQPPQAPQPLQPRKKRVRRTT 397
           GEETAQS                               APQPPQAPQPLQPRKKRVRRTT
Sbjct: 314 GEETAQSALFGFQHDASNHTIVGLGPNQVPEMKETTLQAPQPPQAPQPLQPRKKRVRRTT 373

Query: 398 QLRRTTGAPDITWGMLKKTTQEAERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENK 457
           QLRRTTGAPDITWGMLKKTTQEAERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENK
Sbjct: 374 QLRRTTGAPDITWGMLKKTTQEAERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENK 433

Query: 458 Q 458
           Q
Sbjct: 434 Q 434


>gi|41872344 periphilin 1 isoform 3 [Homo sapiens]
          Length = 367

 Score =  697 bits (1799), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK
Sbjct: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180

Query: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240
           RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK
Sbjct: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240

Query: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300
           LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE
Sbjct: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300

Query: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 341
           IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI
Sbjct: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 341


>gi|41872368 periphilin 1 isoform 2 [Homo sapiens]
          Length = 374

 Score =  697 bits (1799), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 8   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 67

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 68  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 127

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK
Sbjct: 128 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 187

Query: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240
           RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK
Sbjct: 188 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 247

Query: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300
           LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE
Sbjct: 248 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 307

Query: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 341
           IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI
Sbjct: 308 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 348


>gi|219842247 periphilin 1 isoform 7 [Homo sapiens]
          Length = 348

 Score =  645 bits (1663), Expect = 0.0
 Identities = 321/341 (94%), Positives = 322/341 (94%), Gaps = 19/341 (5%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH           
Sbjct: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH----------- 169

Query: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240
                   R+KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK
Sbjct: 170 --------RNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 221

Query: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300
           LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE
Sbjct: 222 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 281

Query: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 341
           IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI
Sbjct: 282 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 322


>gi|41872349 periphilin 1 isoform 4 [Homo sapiens]
          Length = 319

 Score =  528 bits (1361), Expect = e-150
 Identities = 266/273 (97%), Positives = 266/273 (97%), Gaps = 2/273 (0%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 188
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE
Sbjct: 81  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140

Query: 189 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 248
           RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 141 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 200

Query: 249 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 308
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD
Sbjct: 201 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 260

Query: 309 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 341
           CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI
Sbjct: 261 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 293


>gi|219842250 periphilin 1 isoform 8 [Homo sapiens]
          Length = 293

 Score =  476 bits (1225), Expect = e-134
 Identities = 246/273 (90%), Positives = 247/273 (90%), Gaps = 21/273 (7%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 14  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 73

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 188
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR                  
Sbjct: 74  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR------------------ 115

Query: 189 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 248
            +KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 116 -NKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 174

Query: 249 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 308
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD
Sbjct: 175 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 234

Query: 309 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 341
           CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI
Sbjct: 235 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 267


>gi|41872339 periphilin 1 isoform 5 [Homo sapiens]
          Length = 258

 Score =  455 bits (1171), Expect = e-128
 Identities = 229/236 (97%), Positives = 229/236 (97%), Gaps = 2/236 (0%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 188
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE
Sbjct: 81  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140

Query: 189 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 248
           RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 141 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 200

Query: 249 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 304
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV
Sbjct: 201 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 256


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 64/272 (23%), Positives = 99/272 (36%), Gaps = 39/272 (14%)

Query: 42  DRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRD 101
           DR    S N+   H   R  ++ R  S  R         + G      DH  SR P  ++
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS-KE 506

Query: 102 MRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKS 161
            +    R S     + R RSP K        SP   +D   SRS S              
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS-------------- 552

Query: 162 YSFHQSQHRKSVRPGASYKRQNEGNPERDKER-----PVQSLKTSRDTSPSSGSAVSSSK 216
               + +HR+S  P     R+   +P +++ER       +    SR  SP+  S  S  +
Sbjct: 553 ---EEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609

Query: 217 VLDKP-----SRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEP 271
              K      SR   KE   + S+ ++++ + S +S +P   +++   T      Q   P
Sbjct: 610 ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPS-QSTVPRSPDWKRSPTRTSSLSQNRTP 668

Query: 272 ESNTTHGIELF---------EDSQL-TTRSKA 293
              ++H    F         +DSQ   T SKA
Sbjct: 669 SKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 58/215 (26%), Positives = 86/215 (40%), Gaps = 22/215 (10%)

Query: 54  SHVDYRDYDEGRSFSHDRRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSF 111
           SH   R+  + RS SH R S     HRG  S     R +   S+       RD  R +S 
Sbjct: 352 SHNWSRNPSKERSHSHSRSSSKERDHRGSSS----PRKESGRSQSGSPNKQRDHSRSRSP 407

Query: 112 YSSH-YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR 170
             +   +R RSPYK  +     SP   +D   SRS      RS S   +K+       H 
Sbjct: 408 NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA-----RDHS 462

Query: 171 KSVRPGASYKRQNEGNPERDKER-----PVQSLKTSRDTSPSS----GSAVSSSKVLD-K 220
           +S  P  +  R    +P ++++      P +     R  SPS       + SSSK  D +
Sbjct: 463 RSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522

Query: 221 PSRLTEKELAEAASKWAAEKLEKSDESNLPEISEY 255
            SR   KE     S+   ++ ++S   +  E  E+
Sbjct: 523 RSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 52/219 (23%), Positives = 86/219 (39%), Gaps = 36/219 (16%)

Query: 48  SYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDES--GYRWTRDDHSASRQPEYRDMRDG 105
           SYN+  +    + + + RS     RSG   R       + W R+ HS +R    + +   
Sbjct: 268 SYNQASTRSRPQSHSQSRS-PRRSRSGSQKRTHSRVRSHSWKRN-HSRARSRTRKGILSQ 325

Query: 106 FRRKSFYSSHYA-----RERSPYKRDNTFFRESPVGRKDSPHSRSGS------------- 147
             R S   SH       + R+P +  +  +  +P   +   HSRS S             
Sbjct: 326 MGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK 385

Query: 148 -SVSSRSYSPERSKSYSFHQSQH--RKSVRPGASYK-----RQNEGNPERDKER---PVQ 196
            S  S+S SP + + +S  +S +  R   R  + YK     R    N  RD  R   P +
Sbjct: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYK 445

Query: 197 SLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 235
           +   SR  SP+     S S+    P++  ++  + + SK
Sbjct: 446 ARDRSRSRSPNKARDHSRSR---SPNKARDRSRSRSPSK 481



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 43/172 (25%), Positives = 65/172 (37%), Gaps = 7/172 (4%)

Query: 94  SRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRS 153
           SR+  Y       R KS Y+    R R      +   R S  G +   HSR  S    R+
Sbjct: 252 SREKSYSPTEMSSRVKS-YNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRN 310

Query: 154 YSPERSKSYSFHQSQ---HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGS 210
           +S  RS++     SQ   H +S R  +  K QN+    R       S   S++ S S   
Sbjct: 311 HSRARSRTRKGILSQMGRHSQS-RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSR 369

Query: 211 AVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 262
             SSSK  D     + ++ +  +   +  K      S  P  +   + S +P
Sbjct: 370 --SSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 56/180 (31%), Positives = 77/180 (42%), Gaps = 32/180 (17%)

Query: 65  RSFSHDRRSG---PPHRGDES--GYRWTRDDHSASRQPEY-------RDMRDGFRRKSFY 112
           RS S+  +SG   PP R   S     ++R   S  R P+Y       R+     RR+  Y
Sbjct: 431 RSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSY 490

Query: 113 SSHYARER------------SPYKRDNTFFRESP-----VGRKDSPHSRSGSSVSSRSYS 155
           S    R R            S  KR   ++R SP     +    S +S S S  +SRSYS
Sbjct: 491 SPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYS 550

Query: 156 PERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSS 215
             RS+S S  +S+ R S    +S +  + G+  R + R  +S   SR  S S  SA S S
Sbjct: 551 RSRSRSRSRRRSRTRTS--SSSSSRSPSPGSRSRSRSRS-RSRSRSRSQSRSYSSADSYS 607



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 46/149 (30%), Positives = 61/149 (40%), Gaps = 23/149 (15%)

Query: 82  SGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSP 141
           S Y  TR    +SR P  R      + +S  S   +  RSP     +  R  P     S 
Sbjct: 393 SSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPP-----SR 447

Query: 142 HSRSGSSVSSRSYSP--ERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQS-L 198
            SRS  S S   YSP  ER   YS   SQ R+  R   + +R+   +P R + R   S L
Sbjct: 448 SSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERER---ARRRRRSYSPMRKRRRDSPSHL 504

Query: 199 KTSRDT------------SPSSGSAVSSS 215
           +  R T            SPSS  ++SS+
Sbjct: 505 EARRITSARKRPIPYYRPSPSSSGSLSST 533



 Score = 35.8 bits (81), Expect = 0.083
 Identities = 55/205 (26%), Positives = 72/205 (35%), Gaps = 41/205 (20%)

Query: 11  RIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGS-------------YNRY----- 52
           R P  RA PR   S   +       + P    + G+ S             Y+RY     
Sbjct: 406 RSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE 465

Query: 53  ----YSHVDYRDYDEGRSFSHDRRSGP--PHRGDESGYRWTRDDHSASRQP--EYRDMRD 104
               YS  D +  +  R+    R   P    R D   +   R   SA ++P   YR    
Sbjct: 466 RDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPS 525

Query: 105 GF----RRKSFYSSH--------YARERS---PYKRDNTFFRESPVGRKDSPHSRSGSSV 149
                    S+YSS         Y+R RS     +R  T    S   R  SP SRS S  
Sbjct: 526 SSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRS 585

Query: 150 SSRSYSPERSKSYSFHQSQHRKSVR 174
            SRS S  RS+S S+  +    S R
Sbjct: 586 RSRSRSRSRSQSRSYSSADSYSSTR 610



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 50/211 (23%), Positives = 74/211 (35%), Gaps = 41/211 (19%)

Query: 64  GRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPY 123
           G S SHD+   PP               S  ++ + +  R   RR S YS       SP 
Sbjct: 91  GHSASHDKDLTPP-------------PSSRGKKKKKKSTRKKRRRSSSYSP------SPV 131

Query: 124 KRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVR--PGASYKR 181
           K+           +    H R  S    R +S    KS    + +H+K  R  P  S++ 
Sbjct: 132 KKKKK--------KSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRH 183

Query: 182 QNEGNPER---DKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAA 238
           ++   P R    + RP       R  SP  G      K   + SR   K L + + +  +
Sbjct: 184 RHHRCPSRSQSSESRPSSCESRHRGRSPEEG-----QKSRRRHSRRCSKTLCKDSPEAQS 238

Query: 239 EKLEKSDESNLPEISE----YEAGSTAPLFT 265
            +        L  +S       +GS A LFT
Sbjct: 239 SRPPSQPLQMLGYLSARGVITGSGSAADLFT 269


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 77/284 (27%), Positives = 112/284 (39%), Gaps = 37/284 (13%)

Query: 42  DRPGEGSYNRYY------SHV--DYRDYDEGRSFSHDRRS-GPPHRGDESGYRWTRDDHS 92
           D P   SY + Y      SH   +Y  Y +    +  R+S  PP++   +    TR    
Sbjct: 235 DSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSP 294

Query: 93  ASRQ-----PEYRDMRDGFRRKSFYS----SHYARERS--PYKRDNTFFRESPVGRKDSP 141
            SR+     P  R     + R   YS    S Y R RS  P+    +  R SP+  + S 
Sbjct: 295 YSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSR-SPLPSRKSM 353

Query: 142 HSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGN--PERDKERPVQSLK 199
            SRS S   SR  S    K  S  +S+H  S+ P       + G     + KER   +  
Sbjct: 354 KSRSRSPAYSRHSSSHSKKKRSSSRSRH-SSISPVRLPLNSSLGAELSRKKKERAAAAAA 412

Query: 200 TSRDTSPSSGSAV-----SSSKVLDKPSRLTEKELAEAASKWAAEKLEKS-DESNLPEIS 253
              D   S GS V      +S V  K S L  K+L  +       KLEKS  ++ L  ++
Sbjct: 413 AKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSV------KLEKSAPDTELVNVT 466

Query: 254 EYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASK 297
                      T + +  E++  H ++  + +Q T  SK IA K
Sbjct: 467 HLNTEVKNSSDTGKVKLDENSEKHLVKDLK-AQGTRDSKPIALK 509



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 33/167 (19%), Positives = 66/167 (39%), Gaps = 8/167 (4%)

Query: 57  DYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHY 116
           D   + +  +F  DRR     RG +   R  +  H   R+   RD+    + +   S   
Sbjct: 79  DSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS--RDLLKAKQTEKEKSQEV 136

Query: 117 ARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPG 176
           + +    K      R S   ++ +  +           S + S+S   H+ + RK     
Sbjct: 137 SSKSGSMKD-----RISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELK 191

Query: 177 ASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVS-SSKVLDKPS 222
           + +K +++ + +R+  +  +++ + +  S S     S SSK  D PS
Sbjct: 192 SGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS 238


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 77/284 (27%), Positives = 112/284 (39%), Gaps = 37/284 (13%)

Query: 42  DRPGEGSYNRYY------SHV--DYRDYDEGRSFSHDRRS-GPPHRGDESGYRWTRDDHS 92
           D P   SY + Y      SH   +Y  Y +    +  R+S  PP++   +    TR    
Sbjct: 235 DSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSP 294

Query: 93  ASRQ-----PEYRDMRDGFRRKSFYS----SHYARERS--PYKRDNTFFRESPVGRKDSP 141
            SR+     P  R     + R   YS    S Y R RS  P+    +  R SP+  + S 
Sbjct: 295 YSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSR-SPLPSRKSM 353

Query: 142 HSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGN--PERDKERPVQSLK 199
            SRS S   SR  S    K  S  +S+H  S+ P       + G     + KER   +  
Sbjct: 354 KSRSRSPAYSRHSSSHSKKKRSSSRSRH-SSISPVRLPLNSSLGAELSRKKKERAAAAAA 412

Query: 200 TSRDTSPSSGSAV-----SSSKVLDKPSRLTEKELAEAASKWAAEKLEKS-DESNLPEIS 253
              D   S GS V      +S V  K S L  K+L  +       KLEKS  ++ L  ++
Sbjct: 413 AKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSV------KLEKSAPDTELVNVT 466

Query: 254 EYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASK 297
                      T + +  E++  H ++  + +Q T  SK IA K
Sbjct: 467 HLNTEVKNSSDTGKVKLDENSEKHLVKDLK-AQGTRDSKPIALK 509



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 33/167 (19%), Positives = 66/167 (39%), Gaps = 8/167 (4%)

Query: 57  DYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHY 116
           D   + +  +F  DRR     RG +   R  +  H   R+   RD+    + +   S   
Sbjct: 79  DSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS--RDLLKAKQTEKEKSQEV 136

Query: 117 ARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPG 176
           + +    K      R S   ++ +  +           S + S+S   H+ + RK     
Sbjct: 137 SSKSGSMKD-----RISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELK 191

Query: 177 ASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVS-SSKVLDKPS 222
           + +K +++ + +R+  +  +++ + +  S S     S SSK  D PS
Sbjct: 192 SGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS 238


>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
          Length = 282

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 51/161 (31%), Positives = 62/161 (38%), Gaps = 30/161 (18%)

Query: 65  RSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER---S 121
           RS S+ RRS  P R   S  R      S SR   YR  R  + R  +  S Y+R R   S
Sbjct: 117 RSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRS-RYRGSR--YSRSPYSRSPYSRSRYSRS 173

Query: 122 PYKRDNTFFRESPVG-----------------RKDSPHSRSGSSVSSRSYSPERSKSYSF 164
           PY R    +RES  G                      HS+SGSS SSRS S  +S S   
Sbjct: 174 PYSRSR--YRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSS--- 228

Query: 165 HQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTS 205
             ++  KS     S  R    +  R   R  +    SR  S
Sbjct: 229 --ARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRS 267



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 56/201 (27%), Positives = 73/201 (36%), Gaps = 18/201 (8%)

Query: 6   RYEYERIPRER-APPRSHP-SDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDE 63
           RY    +PR R   PR      GY R       +     R       R+ S         
Sbjct: 91  RYGRRDLPRSRQGEPRGRSRGGGYGR-------RSRSYGRRSRSPRRRHRSRSRGPSCSR 143

Query: 64  GRSFSHDRRS----GPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYAR- 118
            RS S  R S     P  R   S  R++R  +S SR  E R     +    + +S Y+R 
Sbjct: 144 SRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRY 203

Query: 119 --ERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPG 176
              RS  K  ++    S    K S   RS SS  SRS S  RS S +  +S  R S R  
Sbjct: 204 HSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMT--RSPPRVSKRKS 261

Query: 177 ASYKRQNEGNPERDKERPVQS 197
            S  R        ++E  + S
Sbjct: 262 KSRSRSKRPPKSPEEEGQMSS 282



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 19/180 (10%)

Query: 85  RWTRDDHSASRQ--PEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPH 142
           R+ R D   SRQ  P  R    G+ R+S   S+  R RSP +R                 
Sbjct: 91  RYGRRDLPRSRQGEPRGRSRGGGYGRRS--RSYGRRSRSPRRRHR--------------- 133

Query: 143 SRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSR 202
           SRS     SRS S  R +   + +S + +S    + Y R         + R   S  +S 
Sbjct: 134 SRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSS 193

Query: 203 DTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 262
             S S  S   SS+   K    T    A  +   +A + + S  S     S   + + +P
Sbjct: 194 GYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSP 253


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 49/185 (26%), Positives = 74/185 (40%), Gaps = 9/185 (4%)

Query: 75  PPHRGDESGYRWTRDDHSASRQPEYRDM-RDGFRRKSFYSSHYARERSPYKRDNTFFRES 133
           PP R         R++    ++ +++   R   R   ++SS  +R RS  K  ++     
Sbjct: 737 PPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSL---- 792

Query: 134 PVGRKDSPHSRSGS-SVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKE 192
           P   +    SRS S S   R++SPER +      + +R S  PGAS KR    +P   K+
Sbjct: 793 PSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKK 852

Query: 193 RPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEI 252
           +       SR  S +   +VS SK             A +AS    E    S E +    
Sbjct: 853 K---RRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVS 909

Query: 253 SEYEA 257
            E EA
Sbjct: 910 QEKEA 914


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 50/217 (23%), Positives = 84/217 (38%), Gaps = 31/217 (14%)

Query: 3   SEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYD 62
           ++G++ Y    RER+  R       +R  +         DR     Y+RY    +YR   
Sbjct: 552 TKGKHSYNSRTRERSRSRDRSRRVRSRTHD--------RDRSRSKEYHRYREQ-EYRR-- 600

Query: 63  EGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH------- 115
            GRS S +RR+ P     +   R  RD  S+ R+      +D +R +   SSH       
Sbjct: 601 RGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES 660

Query: 116 ----YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRK 171
               Y++ R     +N+  RE    R  SP S+   S      S +     S  +++  +
Sbjct: 661 EKRMYSKSRDHNSSNNS--REKKADRDQSPFSKIKQS------SQDNELKSSMLKNKEDE 712

Query: 172 SVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSS 208
            +R     + Q     E D     ++ K   ++SP +
Sbjct: 713 KIRSSVEKENQKSKGQENDHVHE-KNKKFDHESSPGT 748



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 60/245 (24%), Positives = 85/245 (34%), Gaps = 43/245 (17%)

Query: 14  RERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRS 73
           RE  PP S P+    RL         L+ R G     R      YR     RS    RRS
Sbjct: 308 RECNPPNSQPASYQRRL---------LVTRSGRKIKGRGPRR--YRTPSRSRSRDRFRRS 356

Query: 74  G-PPHRGDE----------SGYRWTRDDHSA-------SRQP---------EYRDMRDGF 106
             PPH   E          SG RW + D S         R P         ++R++ +  
Sbjct: 357 ETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESP 416

Query: 107 RRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSY---S 163
            RK+       ++     ++    R S    K     +  +   SRS S E+SKS    S
Sbjct: 417 NRKN-EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDS 475

Query: 164 FHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSR 223
            H     K +R   S  R +E   E++K+   +     R  S      + S       S+
Sbjct: 476 KHNRNEEKRMR-SRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSK 534

Query: 224 LTEKE 228
             EK+
Sbjct: 535 SKEKD 539


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 23/228 (10%)

Query: 44  PGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMR 103
           PG  +  R  S          R+ S    S    R    G  +    H+ SR   +   R
Sbjct: 367 PGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSR 426

Query: 104 DGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKD-SPHSRSGSSVSSRSYSPERSKSY 162
              RR S   S   R      RD   +  SP  R    P  RS     SRS+S +R +  
Sbjct: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRS----RSRSHSGDRYRR- 481

Query: 163 SFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDK-- 220
                +H  S R  +S+      +P R +     SL  SR  SPS   + S S+   +  
Sbjct: 482 GGRGLRHHSSSRSRSSWSL----SPSRSR-----SLTRSRSHSPSPSQSRSRSRSRSQSP 532

Query: 221 -PSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ 267
            PS   EK    AAS    EKL+K++ +     +  E G+  P  T Q
Sbjct: 533 SPSPAREKLTRPAASPAVGEKLKKTEPA-----AGKETGAAKPKLTPQ 575


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 70/346 (20%), Positives = 119/346 (34%), Gaps = 29/346 (8%)

Query: 59  RDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYAR 118
           R+ + GR    D +     + D    R  + D    RQ E    ++  R K+       R
Sbjct: 133 REGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN-RQERRER 191

Query: 119 ERSPYKRDNTFFRESPVGR-KDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGA 177
           ER   K + T  R S  GR ++        +   R    ER +     + + +++ R  A
Sbjct: 192 ERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA 251

Query: 178 SYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWA 237
           S +R+ E + ER++ER        RD            +   K  R TE++      +  
Sbjct: 252 S-ERETERDKERERER-------DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303

Query: 238 AEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASK 297
             + E+  E N     E E         ++  E +  T              R K    K
Sbjct: 304 QRERERERERNRKRERERER--------ERERERQRETERD-----------REKERERK 344

Query: 298 TKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNT 357
            K   ++ R+     G   +   E++   E+       +   E E      +Q    R T
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404

Query: 358 EMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTT 403
           E D DG  E E +   +   +  +  +  + R+K+  R     R T
Sbjct: 405 EKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQT 450


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 50/167 (29%), Positives = 72/167 (43%), Gaps = 26/167 (15%)

Query: 73  SGPPHRGDESGYRWTRDDHSAS-----RQPEYRDMRDGFRRKSFYS------SHYARERS 121
           SG   RG+ S  R  RD  S+S     R  E+R  RDG R  S  S      SH   ER+
Sbjct: 185 SGTQRRGEGSERRPRRDRRSSSGRSKERHREHR-RRDGQRGGSEASKSRSRHSHSGEERA 243

Query: 122 PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK- 180
              +  +    S  GR+ S      +S +S S S  + +    H+S+ + S  P ++YK 
Sbjct: 244 EVAKSGS--SSSSGGRRKS------ASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKE 295

Query: 181 -----RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPS 222
                R+++  P+  + R   S    RD SP S  A  S +    PS
Sbjct: 296 PPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS 342



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 55/266 (20%), Positives = 92/266 (34%), Gaps = 48/266 (18%)

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDG--FRRKSFYSSHYAR 118
           Y   RS S+ R S     GD S   ++      SR P    +R     R +S YSS ++R
Sbjct: 362 YSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSR 421

Query: 119 ERSPYKRDNTFFRESPVGR-----KDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSV 173
            RS ++   +  R S +       K S  +    +  +R+    R+   +      + + 
Sbjct: 422 SRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAE 481

Query: 174 RPGASYKRQNEGNPERDKE------------RPVQSLKTSRDTSPSSGSAVSSSKVLDKP 221
               + K  N   P +               + V+ +K     SPSSG  + + K   KP
Sbjct: 482 AAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKP 541

Query: 222 -------------------SRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 262
                              + +  KE   AA+K  +  L++  +   P I   E      
Sbjct: 542 PLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVA 601

Query: 263 LFTDQ----------PEEPESNTTHG 278
           L T            PE+ E+++  G
Sbjct: 602 LVTSTLPPLPLPPMLPEDKEADSLRG 627



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 69/260 (26%), Positives = 101/260 (38%), Gaps = 33/260 (12%)

Query: 66  SFSHDRRSGPPHRGDESGYRWTRDDHSASRQPE--YRDMRD---GFRRKSFYSSHYARER 120
           S S   R    HR   S  + +++  SA ++P   YR+ +     +RR+   S    R+ 
Sbjct: 268 SSSRKDRDSKAHR---SRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDD 324

Query: 121 SPYK-RDNTFFRE----SPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR---KS 172
           SP   R +   R     SP G   SP+SR     S   YS  RS SYS H S  R    S
Sbjct: 325 SPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPR-SPSPYSRRRSPSYSRHSSYERGGDVS 383

Query: 173 VRPGASYKRQNEGNP--------ERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRL 224
             P +S   +   +P         + + R   S + SR  S    S   S      PS L
Sbjct: 384 PSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTL 443

Query: 225 TEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFED 284
           T K      S  AAE L K+ ++   E +     + A   T +  E  +           
Sbjct: 444 TLK------SSLAAE-LNKNKKARAAEAARAAEAAKAAEAT-KAAEAAAKAAKASNTSTP 495

Query: 285 SQLTTRSKAIASKTKEIEQV 304
           ++  T + A AS+T  ++ V
Sbjct: 496 TKGNTETSASASQTNHVKDV 515


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 50/167 (29%), Positives = 72/167 (43%), Gaps = 26/167 (15%)

Query: 73  SGPPHRGDESGYRWTRDDHSAS-----RQPEYRDMRDGFRRKSFYS------SHYARERS 121
           SG   RG+ S  R  RD  S+S     R  E+R  RDG R  S  S      SH   ER+
Sbjct: 185 SGTQRRGEGSERRPRRDRRSSSGRSKERHREHR-RRDGQRGGSEASKSRSRHSHSGEERA 243

Query: 122 PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK- 180
              +  +    S  GR+ S      +S +S S S  + +    H+S+ + S  P ++YK 
Sbjct: 244 EVAKSGS--SSSSGGRRKS------ASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKE 295

Query: 181 -----RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPS 222
                R+++  P+  + R   S    RD SP S  A  S +    PS
Sbjct: 296 PPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPS 342



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 55/266 (20%), Positives = 92/266 (34%), Gaps = 48/266 (18%)

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDG--FRRKSFYSSHYAR 118
           Y   RS S+ R S     GD S   ++      SR P    +R     R +S YSS ++R
Sbjct: 362 YSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSR 421

Query: 119 ERSPYKRDNTFFRESPVGR-----KDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSV 173
            RS ++   +  R S +       K S  +    +  +R+    R+   +      + + 
Sbjct: 422 SRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAE 481

Query: 174 RPGASYKRQNEGNPERDKE------------RPVQSLKTSRDTSPSSGSAVSSSKVLDKP 221
               + K  N   P +               + V+ +K     SPSSG  + + K   KP
Sbjct: 482 AAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKP 541

Query: 222 -------------------SRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 262
                              + +  KE   AA+K  +  L++  +   P I   E      
Sbjct: 542 PLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVA 601

Query: 263 LFTDQ----------PEEPESNTTHG 278
           L T            PE+ E+++  G
Sbjct: 602 LVTSTLPPLPLPPMLPEDKEADSLRG 627



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 69/260 (26%), Positives = 101/260 (38%), Gaps = 33/260 (12%)

Query: 66  SFSHDRRSGPPHRGDESGYRWTRDDHSASRQPE--YRDMRD---GFRRKSFYSSHYARER 120
           S S   R    HR   S  + +++  SA ++P   YR+ +     +RR+   S    R+ 
Sbjct: 268 SSSRKDRDSKAHR---SRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDD 324

Query: 121 SPYK-RDNTFFRE----SPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR---KS 172
           SP   R +   R     SP G   SP+SR     S   YS  RS SYS H S  R    S
Sbjct: 325 SPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPR-SPSPYSRRRSPSYSRHSSYERGGDVS 383

Query: 173 VRPGASYKRQNEGNP--------ERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRL 224
             P +S   +   +P         + + R   S + SR  S    S   S      PS L
Sbjct: 384 PSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTL 443

Query: 225 TEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFED 284
           T K      S  AAE L K+ ++   E +     + A   T +  E  +           
Sbjct: 444 TLK------SSLAAE-LNKNKKARAAEAARAAEAAKAAEAT-KAAEAAAKAAKASNTSTP 495

Query: 285 SQLTTRSKAIASKTKEIEQV 304
           ++  T + A AS+T  ++ V
Sbjct: 496 TKGNTETSASASQTNHVKDV 515


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo
           sapiens]
          Length = 1227

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 37/159 (23%), Positives = 62/159 (38%), Gaps = 11/159 (6%)

Query: 58  YRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYA 117
           Y+D++E +    D++      GD++G    +D H  S + E      G   + +  S   
Sbjct: 79  YKDWEESKD---DQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERS--- 132

Query: 118 RERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGA 177
           R+R   +R++  +  S    KD    +S      R Y  +R +          +S R G 
Sbjct: 133 RQRERERREHGVYASSKE-EKDWKKEKS----RDRDYDRKRDRDERDRSRHSSRSERDGG 187

Query: 178 SYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSK 216
           S +      PE  + RP  +   SR T     S   SS+
Sbjct: 188 SERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSR 226


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/221 (28%), Positives = 90/221 (40%), Gaps = 47/221 (21%)

Query: 7   YEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGR- 65
           Y Y R  R++  P +     Y  +V  +  +    D      Y R    V Y D  +GR 
Sbjct: 86  YGYRRSGRDKYGPPTRTE--YRLIVENLSSRCSWQDLK---DYMRQAGEVTYADAHKGRK 140

Query: 66  --------SFSHDRRSGPPHRGDESGYRWTR--DDHSASRQPEYRDMRDGFRRKSFYSSH 115
                   S+S  +R+     G E   R  R  +D   SR           RR+S     
Sbjct: 141 NEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR-----------RRRS----- 184

Query: 116 YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRP 175
           Y+R RS + R  +  R S   R     SRSGSS SS S S  RS+S S  +S+ R   + 
Sbjct: 185 YSRSRS-HSRSRSRSRHSRKSR-----SRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238

Query: 176 GASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSK 216
            +  K++   +P ++K         SR  S S+G + S SK
Sbjct: 239 RSRSKKEKSRSPSKEK---------SRSRSHSAGKSRSKSK 270



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 55/208 (26%), Positives = 80/208 (38%), Gaps = 37/208 (17%)

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRK---SFYSSHYA 117
           Y  GRS    RRSG    G  +   +     + S +  ++D++D  R+    ++  +H  
Sbjct: 79  YGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKG 138

Query: 118 R--------------ERSPYKRDNTFFRESPVGRK-----DSPHSRSGSSVSSRSYSPER 158
           R              +R+  K D T       GRK     D P SR       RSYS  R
Sbjct: 139 RKNEGVIEFVSYSDMKRALEKLDGTEVN----GRKIRLVEDKPGSR-----RRRSYSRSR 189

Query: 159 SKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVL 218
           S S S  +S+H +  R      R         K R  +S   SR  S S   + S S+  
Sbjct: 190 SHSRSRSRSRHSRKSR-----SRSGSSKSSHSKSRS-RSRSGSRSRSKSRSRSQSRSRSK 243

Query: 219 DKPSRLTEKELAEAASKWAAEKLEKSDE 246
            + SR   KE + + S  A +   KS +
Sbjct: 244 KEKSRSPSKEKSRSRSHSAGKSRSKSKD 271



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 40/177 (22%), Positives = 68/177 (38%), Gaps = 4/177 (2%)

Query: 37  KPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQ 96
           + P  ++    S++   S    +D  E +  ++D   G P     S ++      S S++
Sbjct: 248 RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDN-VGKPKSRSPSRHKSKSKSRSRSQE 306

Query: 97  PEYRDMRDGF---RRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRS 153
               + + G     R    S   +R RS  K  +     S    KD    R  S   SRS
Sbjct: 307 RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS 366

Query: 154 YSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGS 210
            S  RSKS    +   ++  + G+S K++ E         P +S+   R+ + S  S
Sbjct: 367 RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESS 423


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/288 (21%), Positives = 120/288 (41%), Gaps = 33/288 (11%)

Query: 132 ESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDK 191
           +SPV  +     ++ S V + + SPE++KS      +  KS     S  ++   +PE+ K
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKS---PVKEEAKSPEKAKSPVKEEAKSPEKAK 723

Query: 192 ERPVQSLKTSRDT---------SPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLE 242
               +  KT             SP    +   +K LD  S    K  A+  ++  A+K  
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP-EAKTPAKEEARSPADKFP 782

Query: 243 KSDESNLPEISEYEAGSTAPLFTD--QPEE------------PESNTTHGIELFEDSQLT 288
           +  +S + E  +    + +PL  D   PE+             E      +++ E  +  
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842

Query: 289 TRSKAIAS-KTKEIEQVYRQDC-ETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQ 346
              KA A+ KT+E +   +++  +      K+  +K+P++EK  +  +     E E   +
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902

Query: 347 --TWQQVPPVRNTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKR 392
             T ++  P +  E+  D  P+ E  E A+  P   +A +P +P +K+
Sbjct: 903 VPTPEKEAPAK-VEVKEDAKPK-EKTEVAKKEPDDAKAKEPSKPAEKK 948


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 56/227 (24%), Positives = 82/227 (36%), Gaps = 19/227 (8%)

Query: 59  RDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASR------QPEYRDMRDGFRRKSFY 112
           R +   RS S  RR+    R   S  R  R  HS SR       P  R      R +   
Sbjct: 246 RRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSR 305

Query: 113 SSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS 172
           S+   R++    ++    +  P     +  SRS S    R  S   ++S    +S  RK 
Sbjct: 306 STSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKL 365

Query: 173 VRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEA 232
            R  +  + + E   ++DKER       SRD    S S    SK  +K     ++E    
Sbjct: 366 SRSPSPRRHKKEKKKDKDKER-------SRDERERSTSKKKKSKDKEK-----DRERKSE 413

Query: 233 ASKWAAEKLEKSDESNLPEISEYE-AGSTAPLFTDQPEEPESNTTHG 278
           + K   +     DE      SE E      P+ T  P+  E +   G
Sbjct: 414 SDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKG 460



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 38/158 (24%), Positives = 61/158 (38%), Gaps = 4/158 (2%)

Query: 44  PGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMR 103
           P    + R  S    R + + RS    R   P  R   S  R  R   ++  + + ++ +
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRS--RRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDK 318

Query: 104 DGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYS 163
           +  R K+   S+    RS         R S  G +     RS     SRS SP R K   
Sbjct: 319 EKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK 378

Query: 164 FHQSQHRKS--VRPGASYKRQNEGNPERDKERPVQSLK 199
                  +S   R  ++ K++   + E+D+ER  +S K
Sbjct: 379 KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 45/179 (25%), Positives = 75/179 (41%), Gaps = 26/179 (14%)

Query: 92  SASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSS 151
           SA+ +P+ ++ +   RR S   S   R R+P              R     SRS     S
Sbjct: 234 SAAIEPDKKEEK---RRHSRSRSRSRRRRTPSS-----------SRHRRSRSRSRRRSHS 279

Query: 152 RSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKER-----PVQSLKTSRDTSP 206
           +S S  RSKS    +S  R+  R   S  +  +   E DKE+     P +S  T+R +  
Sbjct: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE-DKEKKRSKTPPKSYSTARRSRS 338

Query: 207 SSGS-----AVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGST 260
           +S       + S ++   KP R  +++L+ + S    +K +K D+       E E  ++
Sbjct: 339 ASRERRRRRSRSGTRSPKKP-RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS 396


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 53/196 (27%), Positives = 75/196 (38%), Gaps = 12/196 (6%)

Query: 63  EGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH---YARE 119
           EGR      +S   H+ +E   +    D    R     +  D  +RK   SS    ++R 
Sbjct: 69  EGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128

Query: 120 RSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASY 179
           RS  +R  +  RE    RK S  SRS     SRS S ER KS S  + + R+      S 
Sbjct: 129 RSRERRHRSRSRE----RKKS-RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183

Query: 180 KRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKP--SRLTEKELAEAASK-- 235
            R       R + R     +  R   P   S   S      P   R T  +  EA ++  
Sbjct: 184 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL 243

Query: 236 WAAEKLEKSDESNLPE 251
             A+KL++  E  + E
Sbjct: 244 ERAKKLQEQREKEMVE 259


>gi|229577273 BUD13 homolog isoform 2 [Homo sapiens]
          Length = 485

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 61/251 (24%), Positives = 88/251 (35%), Gaps = 17/251 (6%)

Query: 10  ERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSH 69
           E +P  R      P     R+ +  P   P  DR      +   +  D  D    R   H
Sbjct: 111 EDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARH 170

Query: 70  DRRSGPPHR-----GDESGYRWTRDDH---SASRQPEYRDMRDGFRRKSFYSSHYARERS 121
           D  + PP R      D S  R  R D    S  R+P++    D  +      S    ++S
Sbjct: 171 DSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQS 230

Query: 122 PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGAS--- 178
           P  +D+      P  R   P  RS  S  S     +R+KS     S  R+S  PG     
Sbjct: 231 PGHQDSDSDLSPPRNR---PRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH 287

Query: 179 -YKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVL--DKPSRLTEKELAEAASK 235
            Y     G    D +R  Q LK     + +  +    ++ +  DK  R    +L     +
Sbjct: 288 MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR 347

Query: 236 WAAEKLEKSDE 246
             AEK  + DE
Sbjct: 348 RKAEKDSERDE 358


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/234 (22%), Positives = 89/234 (38%), Gaps = 30/234 (12%)

Query: 180 KRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLT---EKELAEAASKW 236
           ++Q +   E +K+   Q+ K  ++TS   G  ++  K   K    T   +K + +   + 
Sbjct: 516 EKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRC 575

Query: 237 AAEKLEKSDESNLPEISEY-EAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA 295
              +++K    ++P  S   ++GS  P       +PES         ED+  T R+KA  
Sbjct: 576 PTPEIQKKSTGDVPHTSVTGDSGSGKPFKIKG--QPESGILRTGTFREDTDDTERNKA-- 631

Query: 296 SKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVR 355
               + E + R   E  G +V  L    PS        +        S   T    PP  
Sbjct: 632 ----QREPLTRARSEEMGRIVPGL----PSGWAKFLDPITGTFRYYHSPTNTVHMYPP-- 681

Query: 356 NTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDIT 409
                 +  P +    T  +    PQ P       +R R  ++L+R+  +PDIT
Sbjct: 682 ------EMAPSSAPPSTPPTHKAKPQIPA------ERDREPSKLKRSYSSPDIT 723


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/234 (22%), Positives = 89/234 (38%), Gaps = 30/234 (12%)

Query: 180 KRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLT---EKELAEAASKW 236
           ++Q +   E +K+   Q+ K  ++TS   G  ++  K   K    T   +K + +   + 
Sbjct: 516 EKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRC 575

Query: 237 AAEKLEKSDESNLPEISEY-EAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA 295
              +++K    ++P  S   ++GS  P       +PES         ED+  T R+KA  
Sbjct: 576 PTPEIQKKSTGDVPHTSVTGDSGSGKPFKIKG--QPESGILRTGTFREDTDDTERNKA-- 631

Query: 296 SKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVR 355
               + E + R   E  G +V  L    PS        +        S   T    PP  
Sbjct: 632 ----QREPLTRARSEEMGRIVPGL----PSGWAKFLDPITGTFRYYHSPTNTVHMYPP-- 681

Query: 356 NTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDIT 409
                 +  P +    T  +    PQ P       +R R  ++L+R+  +PDIT
Sbjct: 682 ------EMAPSSAPPSTPPTHKAKPQIPA------ERDREPSKLKRSYSSPDIT 723


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/234 (22%), Positives = 89/234 (38%), Gaps = 30/234 (12%)

Query: 180 KRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLT---EKELAEAASKW 236
           ++Q +   E +K+   Q+ K  ++TS   G  ++  K   K    T   +K + +   + 
Sbjct: 516 EKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRC 575

Query: 237 AAEKLEKSDESNLPEISEY-EAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA 295
              +++K    ++P  S   ++GS  P       +PES         ED+  T R+KA  
Sbjct: 576 PTPEIQKKSTGDVPHTSVTGDSGSGKPFKIKG--QPESGILRTGTFREDTDDTERNKA-- 631

Query: 296 SKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVR 355
               + E + R   E  G +V  L    PS        +        S   T    PP  
Sbjct: 632 ----QREPLTRARSEEMGRIVPGL----PSGWAKFLDPITGTFRYYHSPTNTVHMYPP-- 681

Query: 356 NTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDIT 409
                 +  P +    T  +    PQ P       +R R  ++L+R+  +PDIT
Sbjct: 682 ------EMAPSSAPPSTPPTHKAKPQIPA------ERDREPSKLKRSYSSPDIT 723


>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
          Length = 1648

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 141  PHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKT 200
            P SRS S+ SSRS    + K  S    + R   R  +  +     +P   +ERP +  + 
Sbjct: 988  PPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRR--QR 1045

Query: 201  SRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYE 256
            S+  S  S S  SSS+   K  +  +K        W   +      S  P  S YE
Sbjct: 1046 SKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101



 Score = 33.1 bits (74), Expect = 0.54
 Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 15/120 (12%)

Query: 101  DMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSP---- 156
            ++R   R +S  SS  +R+++  KR +     +  G +     RS     SRS SP    
Sbjct: 985  ELRPPSRSRSTSSSR-SRKKAKRKRVSREHGRTRSGTRSESRDRS-----SRSASPSVGE 1038

Query: 157  -----ERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSA 211
                 +RSK+ S   S  R S R  A  K+  + + E  +     S +TSR  S S GS+
Sbjct: 1039 ERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSS 1098


>gi|62526045 zinc finger protein 638 [Homo sapiens]
          Length = 1978

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 58/215 (26%), Positives = 78/215 (36%), Gaps = 40/215 (18%)

Query: 71  RRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFF 130
           RRS   HR     +R +R       +P  R  R   R  S Y S  +R RSPY+  N F 
Sbjct: 497 RRSSSSHR-----FRRSRSPMHYMYRPRSRSPRICHRFISRYRSR-SRSRSPYRIRNPF- 549

Query: 131 RESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRP-------GASYKRQN 183
                          GS    RS SPER    S   S  +K++         G  + +Q 
Sbjct: 550 --------------RGSPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQK 595

Query: 184 EGNPERDKERPVQSLKTSRDTSPS--------SGSAVSSSKVLDKPSRLTEKELAEAASK 235
                     P Q  KTS  T PS        S S +    +  K   L +  L+E   K
Sbjct: 596 HLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSEC--K 653

Query: 236 WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEE 270
             ++K   S +  L +      GS   L T+ PE+
Sbjct: 654 QVSDK-AVSLQRKLRKEQSLHYGSVL-LITELPED 686


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,552,697
Number of Sequences: 37866
Number of extensions: 1067204
Number of successful extensions: 6235
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 320
Number of HSP's that attempted gapping in prelim test: 5290
Number of HSP's gapped (non-prelim): 967
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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