Guide to the Human Genome
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Search of human proteins with 47716512

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47716512 mex-3 homolog B [Homo sapiens]
         (569 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47716512 mex-3 homolog B [Homo sapiens]                           1151   0.0  
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]    506   e-143
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]    449   e-126
gi|147902746 MEX3A protein [Homo sapiens]                             390   e-108
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        54   4e-07
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    53   9e-07
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    53   9e-07
gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo sa...    52   1e-06
gi|17402900 far upstream element-binding protein [Homo sapiens]        52   1e-06
gi|161016767 mucin 21 [Homo sapiens]                                   50   4e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   4e-06
gi|217416388 neuralized homolog 1B [Homo sapiens]                      50   7e-06
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap...    49   9e-06
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa...    49   2e-05
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap...    49   2e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  48   2e-05
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            47   5e-05
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    47   5e-05
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               47   6e-05
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               47   6e-05
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               47   6e-05
gi|23397642 GREB1 protein isoform a [Homo sapiens]                     47   6e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         47   6e-05
gi|38788243 myosin regulatory light chain interacting protein [H...    47   6e-05
gi|223278368 neuralized-like [Homo sapiens]                            46   8e-05
gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]         46   8e-05
gi|57864582 hornerin [Homo sapiens]                                    46   8e-05
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s...    46   8e-05
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo...    46   8e-05
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    46   1e-04

>gi|47716512 mex-3 homolog B [Homo sapiens]
          Length = 569

 Score = 1151 bits (2978), Expect = 0.0
 Identities = 569/569 (100%), Positives = 569/569 (100%)

Query: 1   MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPR 60
           MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPR
Sbjct: 1   MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPR 60

Query: 61  KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDV 120
           KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDV
Sbjct: 61  KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDV 120

Query: 121 AMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKG 180
           AMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKG
Sbjct: 121 AMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKG 180

Query: 181 ATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDEND 240
           ATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDEND
Sbjct: 181 ATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDEND 240

Query: 241 FHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSY 300
           FHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSY
Sbjct: 241 FHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSY 300

Query: 301 FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQ 360
           FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQ
Sbjct: 301 FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQ 360

Query: 361 PTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPS 420
           PTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPS
Sbjct: 361 PTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPS 420

Query: 421 NANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGA 480
           NANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGA
Sbjct: 421 NANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGA 480

Query: 481 QLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCM 540
           QLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCM
Sbjct: 481 QLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCM 540

Query: 541 ECANRICEKSEPECPVCHTAVTQAIRIFS 569
           ECANRICEKSEPECPVCHTAVTQAIRIFS
Sbjct: 541 ECANRICEKSEPECPVCHTAVTQAIRIFS 569


>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
          Length = 659

 Score =  506 bits (1303), Expect = e-143
 Identities = 301/510 (59%), Positives = 333/510 (65%), Gaps = 76/510 (14%)

Query: 60  RKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKED 119
           R+KSVN TECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEP+FVVTGRKED
Sbjct: 226 RRKSVNTTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFVVTGRKED 285

Query: 120 VAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPK 179
           VAMA+REI+SAAEHFSMIRASRNKN    G +   PNLPGQTT+QVRVPYRVVGLVVGPK
Sbjct: 286 VAMAKREILSAAEHFSMIRASRNKNGPALGGLSCSPNLPGQTTVQVRVPYRVVGLVVGPK 345

Query: 180 GATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDEN 239
           GATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIE HIA+RTG  IEL +EN
Sbjct: 346 GATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEMHIAMRTGNYIELNEEN 405

Query: 240 DFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDS 299
           DFH NGTDV F+      G   GS W    P   P    +  S+YRNDSSSSLGS STDS
Sbjct: 406 DFHYNGTDVSFE------GGTLGSAWLSSNP--VPPSRARMISNYRNDSSSSLGSGSTDS 457

Query: 300 YFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPEL 359
           YFG         + RLAD+SP SP               G  +      SV S D   + 
Sbjct: 458 YFG---------SNRLADFSPTSPF------------STGNFWFGDTLPSVGSEDLAVD- 495

Query: 360 QPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAP 419
            P FD  P     A  IW  FE      P  P+S                    G  S P
Sbjct: 496 SPAFDSLPT---SAQTIWTPFE------PVNPLS--------------------GFGSDP 526

Query: 420 SNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLG 479
           S    G +  +R     S PRLSP     P + EH LARRVRSDP   G       N +G
Sbjct: 527 S----GNMKTQRRGSQPSTPRLSPTF---PESIEHPLARRVRSDPPSTG-------NHVG 572

Query: 480 AQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFC 539
             LP   P+ ++G++S SSS+  S+SSS    R+   DC +CFE+EVIAALVPCGHNLFC
Sbjct: 573 --LPIYIPAFSNGTNSYSSSNGGSTSSSPPESRR-KHDCVICFENEVIAALVPCGHNLFC 629

Query: 540 MECANRICEKSEPECPVCHTAVTQAIRIFS 569
           MECAN+ICEK  P CPVC TAVTQAI+I S
Sbjct: 630 MECANKICEKRTPSCPVCQTAVTQAIQIHS 659


>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
          Length = 651

 Score =  449 bits (1154), Expect = e-126
 Identities = 281/556 (50%), Positives = 323/556 (58%), Gaps = 88/556 (15%)

Query: 36  LALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAK 95
           L  DQ+S++G              RKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAK
Sbjct: 162 LLADQMSVIG-------------SRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAK 208

Query: 96  TNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPP 155
           TNTYIKTPVRGEEPVF+VTGRKEDV MA+REI+SAAEHFS+IRA+R+K   L GA  GPP
Sbjct: 209 TNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPP 268

Query: 156 NLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVD 215
           NLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQ+THTYIVTP RDKEPVF VTGMPENVD
Sbjct: 269 NLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVD 328

Query: 216 RAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPT 275
           RAREEIEAHI LRTG   +   ++DFHANGTDV  DL          SLW+K     TP 
Sbjct: 329 RAREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLL-----GAAASLWAK-----TPN 378

Query: 276 PGRKP---FSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGN 332
            GR+P    +  R D  ++LG+ S    F  G+    +          P PA  ++ +GN
Sbjct: 379 QGRRPPTATAGLRGD--TALGAPSAPEAFYAGSRGGPSVPD-------PGPASPYSGSGN 429

Query: 333 NNNNGNGYTYTA---GGEASVPSPDGCP-ELQPTFDPAPAPPPGAPLIWAQFERSPGGGP 388
                 G+ + A   G      +PD C       F       P A  IWA FER+     
Sbjct: 430 -----GGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERA----A 480

Query: 389 AAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMA 448
             P  S CS+                GA  P  A        R   G   PR SP L   
Sbjct: 481 PLPAFSGCSTV--------------NGAPGPPAAG------ARRSSGAGTPRHSPTLPEP 520

Query: 449 PGAG-EHHLARRVRSDPGG--------------GGLAYAAYANGLGAQLPGLQPSDTSGS 493
            G   E  L+RR   DP G              GG A++  A  L +       +     
Sbjct: 521 GGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFST-ATSLPSSPAAAACAPLDSG 579

Query: 494 SSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPE 553
           +S +S    S+SS+  L    +R+C VC E EV+AALVPCGHNLFCM+CA RIC KSEPE
Sbjct: 580 ASENSRKPPSASSAPAL----ARECVVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPE 635

Query: 554 CPVCHTAVTQAIRIFS 569
           CP C T  TQAI IFS
Sbjct: 636 CPACRTPATQAIHIFS 651



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 75/256 (29%), Positives = 99/256 (38%), Gaps = 51/256 (19%)

Query: 1   MPSSLFADLERNGSGGGGGGSSGGGETL-------------------------DDQRALQ 35
           MPSSL       G GGGGGG    GE                           D   AL+
Sbjct: 1   MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR 60

Query: 36  LALDQLSLLGL----DSDEGASLYDSEPRKKSVN---MTECVPVPSSEHVAEIVGRQGC- 87
           LALDQLS LGL    D+DE  +  D        +     E VP    E  A         
Sbjct: 61  LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120

Query: 88  --KIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNT 145
              +  L    +     P R   P           A+    ++  A+  S+I  SR K+ 
Sbjct: 121 PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLL--ADQMSVI-GSRKKSV 177

Query: 146 ALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVF 205
            +   VP P +               V  +VG +G  IK ++ +T+TYI TP R +EPVF
Sbjct: 178 NMTECVPVPSS-------------EHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVF 224

Query: 206 EVTGMPENVDRAREEI 221
            VTG  E+V+ A+ EI
Sbjct: 225 IVTGRKEDVEMAKREI 240



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 40/136 (29%), Positives = 48/136 (35%), Gaps = 21/136 (15%)

Query: 330 NGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPP-----GAPLIWAQFERSP 384
           +G     G G    A GE   P P   PE      PAP PPP      A L  A  + S 
Sbjct: 9   DGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSA 68

Query: 385 ----GGGP-----AAPVSSSCSSSASSSASSSSVVFPGGGASAP-------SNANLGLLV 428
               G G      AA   ++ +  A   A+   V   G  A AP       +  +L LL 
Sbjct: 69  LGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLD 128

Query: 429 HRRLHPGTSCPRLSPP 444
                P    PR SPP
Sbjct: 129 PNASPPPPPPPRPSPP 144


>gi|147902746 MEX3A protein [Homo sapiens]
          Length = 520

 Score =  390 bits (1001), Expect = e-108
 Identities = 248/509 (48%), Positives = 282/509 (55%), Gaps = 115/509 (22%)

Query: 61  KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDV 120
           K S N TECVPVP+SEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVF+VTGR+EDV
Sbjct: 127 KGSSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDV 186

Query: 121 AMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKG 180
           A ARREIISAAEHFSMIRASRNK+ A  G  P    LPGQ TI+VRVPYRVVGLVVGPKG
Sbjct: 187 ATARREIISAAEHFSMIRASRNKSGAAFGVAPA---LPGQVTIRVRVPYRVVGLVVGPKG 243

Query: 181 ATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDEND 240
           ATIKRIQQQT+TYI+TPSRD++PVFE+TG P NV+RAREEIE HIA+RTG I+E  +END
Sbjct: 244 ATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNEND 303

Query: 241 FHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSY 300
           F A   D   D  +          W          PG KP S++R +S   +G    DS 
Sbjct: 304 FLAGSPDAAIDSRYSDA-------WR------VHQPGCKPLSTFRQNSLGCIGECGVDSG 350

Query: 301 FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQ 360
           F                      A      G +   G GY +   G        G  E  
Sbjct: 351 F---------------------EAPRLGEQGGDFGYG-GYLFPGYGVGKQDVYYGVAETS 388

Query: 361 PTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPS 420
           P              +WA  E +    P + + SS SSS+SSSA + +   PG   S  +
Sbjct: 389 PP-------------LWAGQENAT---PTSVLFSSASSSSSSSAKARAGP-PGAHRSPAT 431

Query: 421 NANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGA 480
           +A   L    R  PG             P  G   L        GGGGL           
Sbjct: 432 SAGPELAGLPRRPPG------------EPLQGFSKL--------GGGGL----------- 460

Query: 481 QLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCM 540
           + PG                             G RDC VCFESEV AALVPCGHNLFCM
Sbjct: 461 RSPG-----------------------------GGRDCMVCFESEVTAALVPCGHNLFCM 491

Query: 541 ECANRICEKSEPECPVCHTAVTQAIRIFS 569
           ECA RICE+++PECPVCH   TQAIRIFS
Sbjct: 492 ECAVRICERTDPECPVCHITATQAIRIFS 520


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 88/385 (22%), Positives = 128/385 (33%), Gaps = 79/385 (20%)

Query: 70  VPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPV---RGEEPVFVVTGRKEDVAMARRE 126
           VPVP    V  ++GR G  IK ++      I+       G E +  + G  +    A R 
Sbjct: 327 VPVPRHS-VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385

Query: 127 IISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTT------------------IQVRVP 168
           I    +             +L    PGPP  PG                     +   +P
Sbjct: 386 INDLLQ-------------SLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIP 432

Query: 169 YRVVGLVVGPKGATIKRIQQQTHTYI-----VTPSRDKE-PVFEVTGMPENVDRAREEIE 222
               GLV+G  G  +K I QQT  ++     + P+ D    +F + G P+ +D A++ IE
Sbjct: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE 492

Query: 223 AHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITP-TPGRKPF 281
             I    G +  +                   G G  GPG     P   + P  PG  PF
Sbjct: 493 EKI---EGPLCPV-------------------GPGPGGPG-----PAGPMGPFNPG--PF 523

Query: 282 SSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYT 341
           +     +    G      Y   G  ++    Q  A +  PS A + A + N         
Sbjct: 524 NQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPHD-PSKAAAAAADPNAAWAAYYSH 582

Query: 342 YTAGGEASVPSPDGCPELQPTFDPAPAPPPGA----PLIWAQFERSPG---GGPAAPVSS 394
           Y       VP P   P   P     P PPP         W ++ +  G     P AP   
Sbjct: 583 YYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQ 642

Query: 395 SCSSSASSSASSSSVVFPGGGASAP 419
             + +        + V  GGG  AP
Sbjct: 643 DYTKAWEEYYKKQAQVATGGGPGAP 667



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 5/84 (5%)

Query: 153 GPPNLPGQTTI--QVRVPYRVVGLVVGPKGATIKRIQQQTHTYI-VTPSRDKEPVFEV-- 207
           GP + P +T++  + RVP  +VGL++G  G  I +IQQ +   + ++P     P   V  
Sbjct: 135 GPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSL 194

Query: 208 TGMPENVDRAREEIEAHIALRTGG 231
           TG PE+V +A+  ++  ++   GG
Sbjct: 195 TGAPESVQKAKMMLDDIVSRGRGG 218



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 49/201 (24%), Positives = 82/201 (40%), Gaps = 24/201 (11%)

Query: 65  NMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIK-TPVRGEEPVFVV--TGRKEDVA 121
           +MTE   VP    V  I+GR G +I  ++  +   ++ +P  G  P   V  TG  E V 
Sbjct: 144 SMTEEYRVPDGM-VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQ 202

Query: 122 MARR---EIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGP 178
            A+    +I+S        +   N N   NG V            ++ +P    GLV+G 
Sbjct: 203 KAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQ-----------EIMIPAGKAGLVIGK 251

Query: 179 KGATIKRIQQQTHTYIV-----TPSRDKEPVFEVTGMPENVDRAREEIEAHIALR-TGGI 232
            G TIK++Q++    ++     + + + +    + G P  V +A E +   +  R  GG 
Sbjct: 252 GGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGF 311

Query: 233 IELTDENDFHANGTDVGFDLH 253
            +  +       G DV    H
Sbjct: 312 GDRNEYGSRIGGGIDVPVPRH 332



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 4/72 (5%)

Query: 163 IQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRD---KEPVFEVTGMPENVDRARE 219
           I V VP   VG+V+G  G  IK+IQ      I     D    E +  + G P+  + A  
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAAR 384

Query: 220 EIEAHI-ALRTG 230
            I   + +LR+G
Sbjct: 385 IINDLLQSLRSG 396


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 100/413 (24%), Positives = 159/413 (38%), Gaps = 68/413 (16%)

Query: 61   KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYI---KTPVRGEEPVFVVTGRK 117
            K+ V  ++ V VPS+  ++ ++GR GC I A+R  T  +I   K   +  + +  + G  
Sbjct: 1721 KEVVRRSKKVSVPSTV-ISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGT 1779

Query: 118  EDVAMARREIISA------AEHFSMIRASRNKNTALNGAV-PGPPNLPGQTTIQVRVPYR 170
            E    A  ++I+A       E   +I  +R K+++ N  +    P      T  + +   
Sbjct: 1780 ESTRQA-TQLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMT 1838

Query: 171  VVGLVVGPKGATIKRI----QQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIA 226
             V L    + AT   +       TH  I  P  +  P F V+ +P       +   A +A
Sbjct: 1839 TVALSSTSQTATALTVPAISSASTHKTIKNPVNNVRPGFPVS-LPLAYP-PPQFAHALLA 1896

Query: 227  LRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRN 286
             +T   I        H  GT   F     + G  P    S    + +P P   P  S +N
Sbjct: 1897 AQTFQQIRPPRLPMTHFGGT---FPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQN 1953

Query: 287  DSSSSLGSASTDSYFGGGTSSSAAAT--QRLADYSPPSPAL-----------------SF 327
             S S + SA + +     T+SS+A+T      + SP SP++                 + 
Sbjct: 1954 SSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTV 2013

Query: 328  AHNGNNNNNGNGYTYTAGGEASVPSP---DGCPELQPTFDPAPAPPPG----APL----- 375
                +NNN       TA   A+ P P   +  P   P+    PA P G    +PL     
Sbjct: 2014 TTTASNNN-------TAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSA 2066

Query: 376  ----IWAQFERSPGGGPAAPVS-----SSCSSSASSSASSSSVVFPGGGASAP 419
                + +  E+  G  P    +     +S SSS SSSA S+    PG  +  P
Sbjct: 2067 SPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEP 2119



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 88/403 (21%), Positives = 120/403 (29%), Gaps = 56/403 (13%)

Query: 94   AKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPG 153
            A T+  IK PV    P F V+             + AA+ F  IR  R   T   G  P 
Sbjct: 1860 ASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPP 1919

Query: 154  PPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTH---------------TYIVTPS 198
              +  G   ++   P R       PK   + R   Q                 T   + S
Sbjct: 1920 AQSTWGPFPVRPLSPARATN---SPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSS 1976

Query: 199  RDKEPVFEVTGMPENVDRARE----EIEAHIALRTGGIIELTDENDFHANGTDVGFDLHH 254
                P     G P +    R+     ++   A  T      ++ N    N T        
Sbjct: 1977 ASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKE 2036

Query: 255  GSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQR 314
                S P S      PS    PG    +S  +  S+S    ++ S    G+      T  
Sbjct: 2037 HYPVSSPSS------PSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNT 2090

Query: 315  LADYSPPSPALSFAHNGNNNNNGN-----------------GYTYTAGGEASVPSPDGCP 357
                S  S   S AH+      G+                     T    A+  +P   P
Sbjct: 2091 RPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVP 2150

Query: 358  ELQPTFDPAPAPPPGAPLIWAQFE----RSPGGGPAAPVSSSCSSSASSSA--SSSSVVF 411
               P   P P  P G P    + E    R P  G  AP  +S S   SS A  S + +  
Sbjct: 2151 STAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKR 2210

Query: 412  PGGGASA---PSNANLGLLVHRRLHPGTS--CPRLSPPLHMAP 449
            P    S+   PS  +        +HP      P  S PL   P
Sbjct: 2211 PHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLPFGP 2253



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 13/24 (54%), Positives = 16/24 (66%)

Query: 2   PSSLFADLERNGSGGGGGGSSGGG 25
           PSS  +  + + SGGGGGG  GGG
Sbjct: 83  PSSSESSSDSDNSGGGGGGGGGGG 106



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 11/19 (57%), Positives = 14/19 (73%)

Query: 7   ADLERNGSGGGGGGSSGGG 25
           +D + +G GGGGGG  GGG
Sbjct: 90  SDSDNSGGGGGGGGGGGGG 108



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 13/23 (56%), Positives = 14/23 (60%)

Query: 3   SSLFADLERNGSGGGGGGSSGGG 25
           SS  +D    G GGGGGG  GGG
Sbjct: 88  SSSDSDNSGGGGGGGGGGGGGGG 110


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 100/413 (24%), Positives = 159/413 (38%), Gaps = 68/413 (16%)

Query: 61   KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYI---KTPVRGEEPVFVVTGRK 117
            K+ V  ++ V VPS+  ++ ++GR GC I A+R  T  +I   K   +  + +  + G  
Sbjct: 1470 KEVVRRSKKVSVPSTV-ISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGT 1528

Query: 118  EDVAMARREIISA------AEHFSMIRASRNKNTALNGAV-PGPPNLPGQTTIQVRVPYR 170
            E    A  ++I+A       E   +I  +R K+++ N  +    P      T  + +   
Sbjct: 1529 ESTRQA-TQLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMT 1587

Query: 171  VVGLVVGPKGATIKRI----QQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIA 226
             V L    + AT   +       TH  I  P  +  P F V+ +P       +   A +A
Sbjct: 1588 TVALSSTSQTATALTVPAISSASTHKTIKNPVNNVRPGFPVS-LPLAYP-PPQFAHALLA 1645

Query: 227  LRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRN 286
             +T   I        H  GT   F     + G  P    S    + +P P   P  S +N
Sbjct: 1646 AQTFQQIRPPRLPMTHFGGT---FPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQN 1702

Query: 287  DSSSSLGSASTDSYFGGGTSSSAAAT--QRLADYSPPSPAL-----------------SF 327
             S S + SA + +     T+SS+A+T      + SP SP++                 + 
Sbjct: 1703 SSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTV 1762

Query: 328  AHNGNNNNNGNGYTYTAGGEASVPSP---DGCPELQPTFDPAPAPPPG----APL----- 375
                +NNN       TA   A+ P P   +  P   P+    PA P G    +PL     
Sbjct: 1763 TTTASNNN-------TAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSA 1815

Query: 376  ----IWAQFERSPGGGPAAPVS-----SSCSSSASSSASSSSVVFPGGGASAP 419
                + +  E+  G  P    +     +S SSS SSSA S+    PG  +  P
Sbjct: 1816 SPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEP 1868



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 88/403 (21%), Positives = 120/403 (29%), Gaps = 56/403 (13%)

Query: 94   AKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPG 153
            A T+  IK PV    P F V+             + AA+ F  IR  R   T   G  P 
Sbjct: 1609 ASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPP 1668

Query: 154  PPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTH---------------TYIVTPS 198
              +  G   ++   P R       PK   + R   Q                 T   + S
Sbjct: 1669 AQSTWGPFPVRPLSPARATN---SPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSS 1725

Query: 199  RDKEPVFEVTGMPENVDRARE----EIEAHIALRTGGIIELTDENDFHANGTDVGFDLHH 254
                P     G P +    R+     ++   A  T      ++ N    N T        
Sbjct: 1726 ASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKE 1785

Query: 255  GSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQR 314
                S P S      PS    PG    +S  +  S+S    ++ S    G+      T  
Sbjct: 1786 HYPVSSPSS------PSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNT 1839

Query: 315  LADYSPPSPALSFAHNGNNNNNGN-----------------GYTYTAGGEASVPSPDGCP 357
                S  S   S AH+      G+                     T    A+  +P   P
Sbjct: 1840 RPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVP 1899

Query: 358  ELQPTFDPAPAPPPGAPLIWAQFE----RSPGGGPAAPVSSSCSSSASSSA--SSSSVVF 411
               P   P P  P G P    + E    R P  G  AP  +S S   SS A  S + +  
Sbjct: 1900 STAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKR 1959

Query: 412  PGGGASA---PSNANLGLLVHRRLHPGTS--CPRLSPPLHMAP 449
            P    S+   PS  +        +HP      P  S PL   P
Sbjct: 1960 PHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLPFGP 2002



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 13/24 (54%), Positives = 16/24 (66%)

Query: 2   PSSLFADLERNGSGGGGGGSSGGG 25
           PSS  +  + + SGGGGGG  GGG
Sbjct: 83  PSSSESSSDSDNSGGGGGGGGGGG 106



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 11/19 (57%), Positives = 14/19 (73%)

Query: 7   ADLERNGSGGGGGGSSGGG 25
           +D + +G GGGGGG  GGG
Sbjct: 90  SDSDNSGGGGGGGGGGGGG 108



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 13/23 (56%), Positives = 14/23 (60%)

Query: 3   SSLFADLERNGSGGGGGGSSGGG 25
           SS  +D    G GGGGGG  GGG
Sbjct: 88  SSSDSDNSGGGGGGGGGGGGGGG 110


>gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo
           sapiens]
          Length = 497

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 5/91 (5%)

Query: 478 LGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNL 537
           L A L   Q       SS +S     S+     R +  + C +C +  +    VPCGH +
Sbjct: 410 LVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLV 469

Query: 538 FCMECANRICEKSEPECPVCHTAVTQAIRIF 568
            C +CA  +      +CP+C+T +T   +IF
Sbjct: 470 TCKQCAEAV-----DKCPMCYTVITFKQKIF 495


>gi|17402900 far upstream element-binding protein [Homo sapiens]
          Length = 644

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 72/284 (25%), Positives = 110/284 (38%), Gaps = 58/284 (20%)

Query: 12  NGSGGGGGGSSGGGETLDDQR-ALQLALDQLSLLGLDSDEGASLYD-------------S 57
           +GS GGGGG  GGG   D  + ALQ A    + +G D+    +  D              
Sbjct: 12  SGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGD 71

Query: 58  EPRKKSVN---------------------MTECVPVPSSEHVAEIVGRQGCKIKALRAKT 96
           +P  K V                      MTE   VP    V  I+GR G +I  ++ ++
Sbjct: 72  QPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGM-VGFIIGRGGEQISRIQQES 130

Query: 97  NTYIK-TPVRGEEPV--FVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPG 153
              I+  P  G  P    ++TG  E V  A+R +    E          K     G   G
Sbjct: 131 GCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVE----------KGRPAPGFHHG 180

Query: 154 PPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIV-----TPSRDKEPVFEVT 208
               PG    ++ +P    GLV+G  G TIK++Q++    +V       +   +    +T
Sbjct: 181 DG--PGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRIT 238

Query: 209 GMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDL 252
           G P  V +A+E +   +    GG  E+ +E      G + G D+
Sbjct: 239 GDPYKVQQAKEMV-LELIRDQGGFREVRNEYGSRIGGNE-GIDV 280



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 94/375 (25%), Positives = 129/375 (34%), Gaps = 69/375 (18%)

Query: 70  VPVPSSEHVAEIVGRQGCKIKALRAKTNTYIK-TPVRGEEP--VFVVTGRKEDVAMARRE 126
           VP+P    V  ++GR G  IK ++      I+  P  G  P  +  +TG  +    A   
Sbjct: 280 VPIPRFA-VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEI 338

Query: 127 I------ISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKG 180
           I      + A          R +         GPP   G       VP    GL++G  G
Sbjct: 339 ITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPG--GLQEFNFIVPTGKTGLIIGKGG 396

Query: 181 ATIKRIQQQTHTYIV---TPSRDKEP---VFEVTGMPENVDRAREEIEAHIALRTGGIIE 234
            TIK I QQ+   I     P  + +P   +F + G P+ +D AR+ IE  I    G +  
Sbjct: 397 ETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIG---GPVNP 453

Query: 235 LTDENDFHANGTDVGFDLHHGSGGSGPGSLWS--KPTPSITPTPGRKPFSSYRNDSSSSL 292
           L        +G       H   G  GPG+      P P     PG  P       +    
Sbjct: 454 LGPPVPHGPHGVP---GPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGW 510

Query: 293 GS--------ASTDSYFGGGTSSSAAATQRLADY----SPPSPALSFAHNGNNNNNGNGY 340
           G+        A  D    G   +SAA     A Y    + P PA           NG   
Sbjct: 511 GNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQ-- 568

Query: 341 TYTAGGEASVPSPDGCPELQPTFD----------PAP--APPPGAP---LIWAQFER--- 382
                G+   P+P G  +    ++          PAP  APP G P     WA++ R   
Sbjct: 569 -----GDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQA 623

Query: 383 ------SPGGGPAAP 391
                 SP G P  P
Sbjct: 624 AYYAQTSPQGMPQHP 638



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 42/172 (24%), Positives = 67/172 (38%), Gaps = 32/172 (18%)

Query: 65  NMTECVPVPSSEHVAEIVGRQGCKIKALRAKT------------NTYIKTPVRGEEPVFV 112
           N  + + +P+S+    ++G+ G  IK L+ +             NT    P+R       
Sbjct: 185 NAVQEIMIPASK-AGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLR------- 236

Query: 113 VTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVV 172
           +TG    V  A+  ++         R  RN+  +  G         G   I V +P   V
Sbjct: 237 ITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIG---------GNEGIDVPIPRFAV 287

Query: 173 GLVVGPKGATIKRIQQQTHTYIVTPSRD---KEPVFEVTGMPENVDRAREEI 221
           G+V+G  G  IK+IQ      I     D    E + ++TG P+    A E I
Sbjct: 288 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEII 339


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 68/299 (22%), Positives = 111/299 (37%), Gaps = 43/299 (14%)

Query: 229 TGGIIELTDENDFHANGTDV-------------GFDLHHGSGGSGPGSLWSKPTPSITPT 275
           T   + +   ++FH   + +             G  +   S  S   S  S  T S + T
Sbjct: 68  TSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESST 127

Query: 276 PGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNN 335
           P     ++  +DSS++   AST +     T+SS A+T   ++ S  S   S A N  ++ 
Sbjct: 128 PSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESST 187

Query: 336 NGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFER--SPGGGPAAPVS 393
             +  +     E+S  S                   GA        R  S G G A    
Sbjct: 188 VSSRASTATNSESSTTS------------------SGASTATNSESRTTSNGAGTATNSE 229

Query: 394 SSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGE 453
           SS +SS +S+A++S    P  GA   +N+            GT+    S  +     +G 
Sbjct: 230 SSTTSSGASTATNSESSTPSSGAGTATNSESST---TSSGAGTATNSESSTV----SSGI 282

Query: 454 HHLARRVRSDPGGGGLAYA---AYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSG 509
             +     S P  G        +     GA       S T+ S +S++++S SS++SSG
Sbjct: 283 STVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSG 341



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 66/284 (23%), Positives = 103/284 (36%), Gaps = 23/284 (8%)

Query: 246 TDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGT 305
           T  G      S  S P S  S  T S + T      ++  +DSS++   AST +     T
Sbjct: 113 TSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESST 172

Query: 306 SSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTY--------------TAGGEASVP 351
           +SS A+T   ++ S  S   S A N  ++   +G +               TA    S  
Sbjct: 173 TSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESST 232

Query: 352 SPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVF 411
           +  G      +    P+   G          S G G A    SS  SS  S+ ++S    
Sbjct: 233 TSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESST 292

Query: 412 PGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAY 471
           P  GA+  +N+            G +    S     + GA     A    S     G + 
Sbjct: 293 PSSGANTATNSE-----SSTTSSGANTATNSDSSTTSSGAS---TATNSESSTTSSGAST 344

Query: 472 AAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
           A  +        G   +  SGSS++SS +S++++S S     G+
Sbjct: 345 ATNSES-STTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGA 387



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 68/301 (22%), Positives = 109/301 (36%), Gaps = 13/301 (4%)

Query: 234 ELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLG 293
           E +   +  ++ T  G      S  S   S  S  T S + T      ++  ++S ++  
Sbjct: 161 EASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSN 220

Query: 294 SASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSP 353
            A T +     T+SS A+T   ++ S PS     A N  ++   +G       E+S  S 
Sbjct: 221 GAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVS- 279

Query: 354 DGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPG 413
            G   +  +    P+              S G   A    SS +SS +S+A++S      
Sbjct: 280 SGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTS 339

Query: 414 GGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAA 473
            GAS  +N+            G S    S     + G      A    S     G + A 
Sbjct: 340 SGASTATNSESSTT-----SSGASTATNSGSSTTSSGTST---ATNSESSTVSSGASTAT 391

Query: 474 YANGL----GAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAA 529
            +       GA       S T  S +S++++S SS++SSG     +   SV       AA
Sbjct: 392 TSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAA 451

Query: 530 L 530
           L
Sbjct: 452 L 452


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 57/174 (32%), Positives = 77/174 (44%), Gaps = 15/174 (8%)

Query: 346  GEASVPSPDGCPELQ----PTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSAS 401
            G  SVP+P G P       P    A  P   A L  A+  RS     ++  SSS SSS+S
Sbjct: 2492 GMLSVPAP-GVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550

Query: 402  SSASSS-SVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRV 460
            SS+SSS S      G+S P    + L   +R+   T  P+ +      P        RR 
Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQPEVAL---KRVPSPTPAPKEAVREGRPPEPTPAKRKRRS 2607

Query: 461  RSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKG 514
             S       + ++ ++   +       S +S SSSSSSSSSSSSSSS    + G
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSPSPAKPG 2655



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 105/493 (21%), Positives = 168/493 (34%), Gaps = 77/493 (15%)

Query: 37   ALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKT 96
            AL  LSL G  +   A+ Y S  R      +  +  P S H    V   G +  A  A  
Sbjct: 2305 ALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPA 2364

Query: 97   NTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPN 156
            +    T  R    +         V ++  E +S      ++  +R++          PP+
Sbjct: 2365 SL---TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRT---------PPS 2412

Query: 157  LPGQTTI-QVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVD 215
             P Q+ +   R P     +   P  + +   Q Q  + + +   D+         P    
Sbjct: 2413 APSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP---- 2468

Query: 216  RAREEIEAHIALRTGGIIELTDENDFHANGTDVGFD-LHHGSGGSGPGSLWSKPTPSITP 274
                 +    +L +G +   T     H     V    + H   G  P S  ++   ++  
Sbjct: 2469 -----VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523

Query: 275  TPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNN 334
                K   S  + SSSS  S+S+ S     +SS ++++       P  P ++        
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR----- 2578

Query: 335  NNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPG--------APLIWAQFERSPGG 386
                           VPSP   P+        P P P         +    +    S   
Sbjct: 2579 ---------------VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623

Query: 387  GPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLH 446
              ++  SSS SSS+SSS+SSSS       +S+PS A  G           + P+ + P  
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSS-------SSSPSPAKPG---------PQALPKPASPKK 2667

Query: 447  MAPGAGEHHLARR-VRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSS---- 501
              PG       R+ + S      L+Y+     +  + P  QPS     SSSS   S    
Sbjct: 2668 PPPGERRSRSPRKPIDSLRDSRSLSYSP----VERRRPSPQPSPRDQQSSSSERGSRRGQ 2723

Query: 502  -SSSSSSSGLRRK 513
               S S S  RR+
Sbjct: 2724 RGDSRSPSHKRRR 2736



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 77/276 (27%), Positives = 99/276 (35%), Gaps = 47/276 (17%)

Query: 299  SYFGGGTSSSAAATQRLADYSPPSPALS------FAHNGNNNNNGNGYTYTAGGEASVPS 352
            S  G GT  +AA     +  +P +PA +       AH     N     T  A   AS+ S
Sbjct: 2310 SLTGSGTPPTAA-NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTS 2368

Query: 353  PDGCPELQPTFDPAPAPPPGA----------PLIWAQFERSPGGGPAAPVSSSCSSSASS 402
                P L      +P  P  A          PL+     R+P   P+AP  S  +S  + 
Sbjct: 2369 ARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP---PSAPSQSRMTSERAP 2425

Query: 403  SASSSSVVFPGGGASAP-------------SNANLGLLVHRRLHPGTSCPRLSPPLHMAP 449
            S SS     P      P             S+ +  L+       G+             
Sbjct: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS 2485

Query: 450  GAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPG----LQP---------SDTSGSSSS 496
             AG+H+    V + PG             GAQ P     LQP         S +S SSSS
Sbjct: 2486 SAGDHNGMLSVPA-PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544

Query: 497  SSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVP 532
            SSSSSSSSSSSSG     S   S+  + EV    VP
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP 2580


>gi|217416388 neuralized homolog 1B [Homo sapiens]
          Length = 555

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 13/88 (14%)

Query: 494 SSSSSSSSSSSSSSSGLRRKGSR-------------DCSVCFESEVIAALVPCGHNLFCM 540
           SSS+S SS  ++ SS L    S              +C+VCF+ EV   +  CGH   C 
Sbjct: 466 SSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCH 525

Query: 541 ECANRICEKSEPECPVCHTAVTQAIRIF 568
            C  R+  ++   CP+C   +   I+I+
Sbjct: 526 SCGLRLKRQARACCPICRRPIKDVIKIY 553


>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
           sapiens]
          Length = 618

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 502 SSSSSSSGLRR-KGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTA 560
           S  S    LRR +  R C VC + EV    +PCGH + C ECA      S  +CP+C   
Sbjct: 554 SGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECA-----PSLRKCPICRGI 608

Query: 561 VTQAIRIF 568
           +   +R F
Sbjct: 609 IKGTVRTF 616


>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 5/58 (8%)

Query: 511 RRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIF 568
           R +  R C VC + EV    +PCGH + C +CA      S  +CP+C + +   +R F
Sbjct: 550 RLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCA-----PSLRKCPICRSTIKGTVRTF 602


>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 5/58 (8%)

Query: 511 RRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIF 568
           R +  R C VC + EV    +PCGH + C +CA      S  +CP+C + +   +R F
Sbjct: 550 RLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCA-----PSLRKCPICRSTIKGTVRTF 602


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 64/273 (23%), Positives = 102/273 (37%), Gaps = 36/273 (13%)

Query: 257  GGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYF--GGGTSSSAAATQR 314
            G   PGS     TP    TP     +      +  +G  S+ S +   G  SSS + +  
Sbjct: 1039 GSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHH 1098

Query: 315  LADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAP 374
                S  S A +     ++ + G+  +  +    S     G  + + +            
Sbjct: 1099 SHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS------------ 1146

Query: 375  LIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGL--LVHRRL 432
                    S  GG   P SS  +    SS SSS+ + P G  S+  N +L    +     
Sbjct: 1147 --------SQSGGK--PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS 1196

Query: 433  HPGTSCPRLSPPLHMAPGAGEHHLARR-VRSDPGGGGLAYAAYANGL---------GAQL 482
             P     +L+ P+   PG      A+  + S  GG  ++  + ++G+         G+  
Sbjct: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256

Query: 483  PGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
                PS  S ++SSSS SSS SS SS   + GS
Sbjct: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS 1289



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 66/286 (23%), Positives = 103/286 (36%), Gaps = 35/286 (12%)

Query: 256  SGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRL 315
            S GS      S  + S   T G+   S     SSS L S+   S    G+S S  ++Q  
Sbjct: 1091 SSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQ-- 1148

Query: 316  ADYSPPSPALS-FAHNGNNNNNGNGYTYTAGGEASVPSPD-GCPELQPTFDPAPAPPPGA 373
               S   P  S    +G ++ + +      G  +S+ +P    P + P+      PP G+
Sbjct: 1149 ---SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS---RPPGGS 1202

Query: 374  PLIWAQFERSPGGGPA----APVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVH 429
              + +  +  PG  P+    +P+SS    S  S  SSSS     G  S+    + G L  
Sbjct: 1203 DKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSS-----GMKSSSGLGSSGSLSQ 1257

Query: 430  RRLHPGTSCPRLSPPLHMA----PGAGEHHLARRVRSDPGG---------GGLAYAAYAN 476
            +      SC   S     +      +   H + + +S               L +    +
Sbjct: 1258 KTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTS 1317

Query: 477  GLGAQLP---GLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCS 519
            G G + P    +  S  S S   SS  + S     G R K  +D S
Sbjct: 1318 GPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKS 1363


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 68/270 (25%), Positives = 107/270 (39%), Gaps = 40/270 (14%)

Query: 243 ANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFG 302
           A+ +  G      SG + P   W  P+ S   +P    ++S  +DS  +  SAS  S   
Sbjct: 178 ASSSASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCIS--- 234

Query: 303 GGTSSSAAATQRLADYSPPSPA-LSFAHNGNNNNNGNGYTYTAGGEASVPSPDG--CPEL 359
              S+S A+T   + ++ PS + +S + +  + ++ +G+  ++    S+ S  G  CP  
Sbjct: 235 --PSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSA 292

Query: 360 QPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSS-VVFPGGGASA 418
                            WA    S    P+   SSS S S +S+ S S    F   GASA
Sbjct: 293 S----------------WASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASA 336

Query: 419 PSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPG-GGGLAYAAYANG 477
           PS++          H  +     S     +P A          SD G     A  A  + 
Sbjct: 337 PSDSGW------TSHSASGVSTTSDSGWASPSAS----GASTSSDSGWASPSASWASPSA 386

Query: 478 LGAQLPGLQPSDTSGSSSSSSSSSSSSSSS 507
            GA      PSD+  +S S+S +S  S+ S
Sbjct: 387 SGAS----TPSDSGWASPSASGASMPSAPS 412



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 66/274 (24%), Positives = 104/274 (37%), Gaps = 18/274 (6%)

Query: 246 TDVGFDLHHGSGGSGPGSLWSKPTPSITPTPG----RKPFSSYRNDSSSS---LGSASTD 298
           +D G+     SG S P + W+ P+ S   TP       P +S+ + SS S     SAS  
Sbjct: 112 SDSGWASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWT 171

Query: 299 SYFGGGTSSSAAATQRLADYSPPSPA---LSFAHNGNNNNNGNGYTYTAGGEASVPSPDG 355
           S      SSSA+     +D    SP+   +S + +  ++ +  G+  T        S   
Sbjct: 172 SPSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSAS 231

Query: 356 CPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSS-ASSSASSSSVVFPGG 414
           C  + P+   A          WA    S      +  S+S  S  ASSSAS  S+    G
Sbjct: 232 C--ISPSASGASTSSDSG---WASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSG 286

Query: 415 GA--SAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYA 472
               SA   ++           G+S P +S    ++        A    +    G  +++
Sbjct: 287 WVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHS 346

Query: 473 AYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSS 506
           A      +      PS +  S+SS S  +S S+S
Sbjct: 347 ASGVSTTSDSGWASPSASGASTSSDSGWASPSAS 380



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 53/198 (26%), Positives = 81/198 (40%), Gaps = 31/198 (15%)

Query: 256 SGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYF----GGGTSSSAAA 311
           SG + P + W   + S   T     ++S    SS+S  S ++DS +        SSSA+ 
Sbjct: 246 SGWASPSASWVSTSTSRASTSSDSGWAS----SSASWDSITSDSGWVCPSASWASSSASW 301

Query: 312 TQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPE-----LQPTFDPA 366
               +D    SP++S A    +  + +G+   +   AS PS  G        +  T D  
Sbjct: 302 ASAPSDSGSSSPSVSRA----STLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSG 357

Query: 367 PAPPP--GAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANL 424
            A P   GA         SP    A+P +S  S+ + S  +S S      GAS PS  + 
Sbjct: 358 WASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSA----SGASMPSAPS- 412

Query: 425 GLLVHRRLHPGTSCPRLS 442
                  L PG+  P+L+
Sbjct: 413 -------LCPGSCFPQLT 423


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 42/121 (34%), Positives = 57/121 (47%), Gaps = 23/121 (19%)

Query: 388 PAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHM 447
           PA P SSS SSS+SSS S        GG   P+   L  L              SPP  +
Sbjct: 44  PAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLG-------------SPPQQL 90

Query: 448 APGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSS 507
           +  A   H    + S P    +  A+     GA LP   PS +S SSSSS+S+SS+S+++
Sbjct: 91  S--AATPHGINDILSRPS---MPVAS-----GAALPSASPSGSSSSSSSSASASSASAAA 140

Query: 508 S 508
           +
Sbjct: 141 A 141



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 19/152 (12%)

Query: 303 GGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGG---EASVPSPDGCPEL 359
           G  SSS++++      S PSP L   + G       G   + G    + S  +P G  ++
Sbjct: 46  GPPSSSSSSSSS----SSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDI 101

Query: 360 QPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAP 419
                P+     GA L  A    SP G      SSS SSS++S++S+S+       A+A 
Sbjct: 102 LSR--PSMPVASGAALPSA----SPSG------SSSSSSSSASASSASAAAAAAAAAAAA 149

Query: 420 SNANLGLLVHRRLHPGTSCPRLSPPLHMAPGA 451
           +++  GLL         S P   P L+ +P A
Sbjct: 150 ASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSA 181


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 43/149 (28%), Positives = 60/149 (40%), Gaps = 18/149 (12%)

Query: 388 PAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHM 447
           P  P+S+S SSS +++++SS+   P      P+++   L     +    +          
Sbjct: 16  PQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGG 75

Query: 448 APGAGEHHLARRVRSDPGGGGLA---------YAAYANGLGAQLPGLQ---------PSD 489
             G G          + GGGG            AA +NG G    G+          P +
Sbjct: 76  GGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPIN 135

Query: 490 TSGSSSSSSSSSSSSSSSSGLRRKGSRDC 518
            S  SSSSSSSSSSSSSSS      S  C
Sbjct: 136 ASTGSSSSSSSSSSSSSSSSSSSSSSSSC 164



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/193 (30%), Positives = 72/193 (37%), Gaps = 45/193 (23%)

Query: 320 PPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQ--PT-FDPAPAPPPGAPLI 376
           PP P +S       + + +G T +     S P+P   P     PT F P P     A   
Sbjct: 15  PPQPPIS------TSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAA-- 66

Query: 377 WAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGT 436
            A    S GGG     S     S+ +          GGG    SN N             
Sbjct: 67  -AATVTSTGGGGGGGGSGGGGGSSGNGGG-------GGGGGGGSNCN------------- 105

Query: 437 SCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSS 496
             P L+   + + G G    A        GGG+A +   N   A       S +S SSSS
Sbjct: 106 --PNLAAASNGSGGGGGGISA--------GGGVASSTPIN---ASTGSSSSSSSSSSSSS 152

Query: 497 SSSSSSSSSSSSG 509
           SSSSSSSSSSS G
Sbjct: 153 SSSSSSSSSSSCG 165



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 32/165 (19%)

Query: 263 SLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPS 322
           S  S P PSI P     P        +S+  +A+T +  GGG     +            
Sbjct: 35  SATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSG----------- 83

Query: 323 PALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFER 382
                   G   ++GNG     GG  S  +P+    L    + +     G          
Sbjct: 84  --------GGGGSSGNGGGGGGGGGGSNCNPN----LAAASNGSGGGGGGI--------- 122

Query: 383 SPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLL 427
           S GGG A+    + S+ +SSS+SSSS       +S+ S+++ G L
Sbjct: 123 SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 254 HGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQ 313
           +GSGG G G        S TP       SS  + SSSS  S+S+ S     +SSS     
Sbjct: 113 NGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSS----SSSSSCGPLP 168

Query: 314 RLADYSPPSPALSFAHN 330
               YS PSP  +   N
Sbjct: 169 GKPVYSTPSPVENTPQN 185



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 42/166 (25%), Positives = 67/166 (40%), Gaps = 24/166 (14%)

Query: 268 PTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSF 327
           PT  + P P   P S+  + S ++  ++S  S         A++   L    P + A + 
Sbjct: 10  PTQLVPPQP---PISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAA 66

Query: 328 AHNGNNNNNGNGYTYTAGGEASVPSPDG---------C-PELQPTFDPAPAPPPGAPLIW 377
           A    +   G G   + GG  S  +  G         C P L    + +     G     
Sbjct: 67  AATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGI---- 122

Query: 378 AQFERSPGGGPAA--PVSSSCSSSASSSASSSSVVFPGGGASAPSN 421
                S GGG A+  P+++S  SS+SSS+SSSS       +S+ S+
Sbjct: 123 -----SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSS 163



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 12  NGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVP 71
           NGSGGGGGG S GG                S     S   +S   S     S + + C P
Sbjct: 113 NGSGGGGGGISAGGGVASSTPI------NASTGSSSSSSSSSSSSSSSSSSSSSSSSCGP 166

Query: 72  VP 73
           +P
Sbjct: 167 LP 168



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 7  ADLERNGSGGGGGGSSGGG 25
          A +   G GGGGGGS GGG
Sbjct: 68 ATVTSTGGGGGGGGSGGGG 86


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 43/149 (28%), Positives = 60/149 (40%), Gaps = 18/149 (12%)

Query: 388 PAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHM 447
           P  P+S+S SSS +++++SS+   P      P+++   L     +    +          
Sbjct: 16  PQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGG 75

Query: 448 APGAGEHHLARRVRSDPGGGGLA---------YAAYANGLGAQLPGLQ---------PSD 489
             G G          + GGGG            AA +NG G    G+          P +
Sbjct: 76  GGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPIN 135

Query: 490 TSGSSSSSSSSSSSSSSSSGLRRKGSRDC 518
            S  SSSSSSSSSSSSSSS      S  C
Sbjct: 136 ASTGSSSSSSSSSSSSSSSSSSSSSSSSC 164



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/193 (30%), Positives = 72/193 (37%), Gaps = 45/193 (23%)

Query: 320 PPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQ--PT-FDPAPAPPPGAPLI 376
           PP P +S       + + +G T +     S P+P   P     PT F P P     A   
Sbjct: 15  PPQPPIS------TSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAA-- 66

Query: 377 WAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGT 436
            A    S GGG     S     S+ +          GGG    SN N             
Sbjct: 67  -AATVTSTGGGGGGGGSGGGGGSSGNGGG-------GGGGGGGSNCN------------- 105

Query: 437 SCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSS 496
             P L+   + + G G    A        GGG+A +   N   A       S +S SSSS
Sbjct: 106 --PNLAAASNGSGGGGGGISA--------GGGVASSTPIN---ASTGSSSSSSSSSSSSS 152

Query: 497 SSSSSSSSSSSSG 509
           SSSSSSSSSSS G
Sbjct: 153 SSSSSSSSSSSCG 165



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 32/165 (19%)

Query: 263 SLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPS 322
           S  S P PSI P     P        +S+  +A+T +  GGG     +            
Sbjct: 35  SATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSG----------- 83

Query: 323 PALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFER 382
                   G   ++GNG     GG  S  +P+    L    + +     G          
Sbjct: 84  --------GGGGSSGNGGGGGGGGGGSNCNPN----LAAASNGSGGGGGGI--------- 122

Query: 383 SPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLL 427
           S GGG A+    + S+ +SSS+SSSS       +S+ S+++ G L
Sbjct: 123 SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 254 HGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQ 313
           +GSGG G G        S TP       SS  + SSSS  S+S+ S     +SSS     
Sbjct: 113 NGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSS----SSSSSCGPLP 168

Query: 314 RLADYSPPSPALSFAHN 330
               YS PSP  +   N
Sbjct: 169 GKPVYSTPSPVENTPQN 185



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 42/166 (25%), Positives = 67/166 (40%), Gaps = 24/166 (14%)

Query: 268 PTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSF 327
           PT  + P P   P S+  + S ++  ++S  S         A++   L    P + A + 
Sbjct: 10  PTQLVPPQP---PISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAA 66

Query: 328 AHNGNNNNNGNGYTYTAGGEASVPSPDG---------C-PELQPTFDPAPAPPPGAPLIW 377
           A    +   G G   + GG  S  +  G         C P L    + +     G     
Sbjct: 67  AATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGI---- 122

Query: 378 AQFERSPGGGPAA--PVSSSCSSSASSSASSSSVVFPGGGASAPSN 421
                S GGG A+  P+++S  SS+SSS+SSSS       +S+ S+
Sbjct: 123 -----SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSS 163



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 12  NGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVP 71
           NGSGGGGGG S GG                S     S   +S   S     S + + C P
Sbjct: 113 NGSGGGGGGISAGGGVASSTPI------NASTGSSSSSSSSSSSSSSSSSSSSSSSSCGP 166

Query: 72  VP 73
           +P
Sbjct: 167 LP 168



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 7  ADLERNGSGGGGGGSSGGG 25
          A +   G GGGGGGS GGG
Sbjct: 68 ATVTSTGGGGGGGGSGGGG 86



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 348 ASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSS 407
           A V SP    E     +  P  P  AP +  +  R PG  P++  SSS SSS + + SSS
Sbjct: 418 AQVQSPPSRVETSVIKERVPDSPSPAPSL--EEGRRPGSHPSSHRSSSVSSSPARTESSS 475


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 43/149 (28%), Positives = 60/149 (40%), Gaps = 18/149 (12%)

Query: 388 PAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHM 447
           P  P+S+S SSS +++++SS+   P      P+++   L     +    +          
Sbjct: 16  PQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGG 75

Query: 448 APGAGEHHLARRVRSDPGGGGLA---------YAAYANGLGAQLPGLQ---------PSD 489
             G G          + GGGG            AA +NG G    G+          P +
Sbjct: 76  GGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPIN 135

Query: 490 TSGSSSSSSSSSSSSSSSSGLRRKGSRDC 518
            S  SSSSSSSSSSSSSSS      S  C
Sbjct: 136 ASTGSSSSSSSSSSSSSSSSSSSSSSSSC 164



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/193 (30%), Positives = 72/193 (37%), Gaps = 45/193 (23%)

Query: 320 PPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQ--PT-FDPAPAPPPGAPLI 376
           PP P +S       + + +G T +     S P+P   P     PT F P P     A   
Sbjct: 15  PPQPPIS------TSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAA-- 66

Query: 377 WAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGT 436
            A    S GGG     S     S+ +          GGG    SN N             
Sbjct: 67  -AATVTSTGGGGGGGGSGGGGGSSGNGGG-------GGGGGGGSNCN------------- 105

Query: 437 SCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSS 496
             P L+   + + G G    A        GGG+A +   N   A       S +S SSSS
Sbjct: 106 --PNLAAASNGSGGGGGGISA--------GGGVASSTPIN---ASTGSSSSSSSSSSSSS 152

Query: 497 SSSSSSSSSSSSG 509
           SSSSSSSSSSS G
Sbjct: 153 SSSSSSSSSSSCG 165



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 32/165 (19%)

Query: 263 SLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPS 322
           S  S P PSI P     P        +S+  +A+T +  GGG     +            
Sbjct: 35  SATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSG----------- 83

Query: 323 PALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFER 382
                   G   ++GNG     GG  S  +P+    L    + +     G          
Sbjct: 84  --------GGGGSSGNGGGGGGGGGGSNCNPN----LAAASNGSGGGGGGI--------- 122

Query: 383 SPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLL 427
           S GGG A+    + S+ +SSS+SSSS       +S+ S+++ G L
Sbjct: 123 SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPL 167



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 254 HGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQ 313
           +GSGG G G        S TP       SS  + SSSS  S+S+ S     +SSS     
Sbjct: 113 NGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSS----SSSSSCGPLP 168

Query: 314 RLADYSPPSPALSFAHN 330
               YS PSP  +   N
Sbjct: 169 GKPVYSTPSPVENTPQN 185



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 42/166 (25%), Positives = 67/166 (40%), Gaps = 24/166 (14%)

Query: 268 PTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSF 327
           PT  + P P   P S+  + S ++  ++S  S         A++   L    P + A + 
Sbjct: 10  PTQLVPPQP---PISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAA 66

Query: 328 AHNGNNNNNGNGYTYTAGGEASVPSPDG---------C-PELQPTFDPAPAPPPGAPLIW 377
           A    +   G G   + GG  S  +  G         C P L    + +     G     
Sbjct: 67  AATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGI---- 122

Query: 378 AQFERSPGGGPAA--PVSSSCSSSASSSASSSSVVFPGGGASAPSN 421
                S GGG A+  P+++S  SS+SSS+SSSS       +S+ S+
Sbjct: 123 -----SAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSS 163



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 12  NGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVP 71
           NGSGGGGGG S GG                S     S   +S   S     S + + C P
Sbjct: 113 NGSGGGGGGISAGGGVASSTPI------NASTGSSSSSSSSSSSSSSSSSSSSSSSSCGP 166

Query: 72  VP 73
           +P
Sbjct: 167 LP 168



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 7  ADLERNGSGGGGGGSSGGG 25
          A +   G GGGGGGS GGG
Sbjct: 68 ATVTSTGGGGGGGGSGGGG 86


>gi|23397642 GREB1 protein isoform a [Homo sapiens]
          Length = 1949

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 19/168 (11%)

Query: 275  TPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNN 334
            +P ++  S   + +SSSL S ++ S  GG +S+   A  +      P P           
Sbjct: 1115 SPMKRERSRSHDSASSSLSSKASGSALGGESSAQPTALPQGEHARSPQP----------- 1163

Query: 335  NNGNGYTYTAGGEASVP-SPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVS 393
              G      A GE   P +  G P       P P P P   L      R+        V+
Sbjct: 1164 -RGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSL------RTGQRSVQVSVT 1216

Query: 394  SSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRL 441
            SSCS  +SSS SSSS V P  G      +   L    R  P    P+L
Sbjct: 1217 SSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPKL 1264



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 42/132 (31%), Positives = 55/132 (41%), Gaps = 18/132 (13%)

Query: 381  ERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPR 440
            +RSP     +    S SSS SS AS S++   GG +SA   A     + +  H  +  PR
Sbjct: 1113 KRSPMKRERSRSHDSASSSLSSKASGSAL---GGESSAQPTA-----LPQGEHARSPQPR 1164

Query: 441  LSPPLHMAPGAGEHHLARR------VRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSS 494
                   APG  +   A +       R  PG       +   G  +    +Q S TS  S
Sbjct: 1165 GPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLRTGQRS----VQVSVTSSCS 1220

Query: 495  SSSSSSSSSSSS 506
              SSSS SSSSS
Sbjct: 1221 QLSSSSGSSSSS 1232


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 42/195 (21%), Positives = 81/195 (41%), Gaps = 8/195 (4%)

Query: 205  FEVTGMPENVDRAR------EEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGG 258
            FE +G P++ D+A+      EE E+  +  +G     +  +   +          +G GG
Sbjct: 2535 FEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGG 2594

Query: 259  SGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADY 318
             G G        S   +P     SS  + SSSS  S+S+ S     +SSS++++   +  
Sbjct: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2654

Query: 319  SPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPG--APLI 376
            S  S + S + + ++++  +  +  +  + + P+P   P  Q           G   P  
Sbjct: 2655 SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSA 2714

Query: 377  WAQFERSPGGGPAAP 391
             +  +++P   P AP
Sbjct: 2715 HSPGKKTPAPQPQAP 2729



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 45/152 (29%), Positives = 60/152 (39%), Gaps = 10/152 (6%)

Query: 378  AQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTS 437
            AQ E+       +  SSS  SS+SSS+SSSS     G      N + G     R     S
Sbjct: 2547 AQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAAS 2606

Query: 438  CPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSS 497
                SP    +  +          S       + ++ ++   +       S +S SSSSS
Sbjct: 2607 SRAASPASSSSSSS----------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656

Query: 498  SSSSSSSSSSSGLRRKGSRDCSVCFESEVIAA 529
            SSSSSSSSSSS        D S   + E   A
Sbjct: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPA 2688



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 58/224 (25%), Positives = 79/224 (35%), Gaps = 55/224 (24%)

Query: 343  TAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASS 402
            T G + S P P       P   PAP  P  AP     F   P   P A + +  +S A +
Sbjct: 2369 TPGSKKSPPEPVDKRAKAPKARPAPPQPSPAP---PAFTSCPAPEPFAELPAPATSLAPA 2425

Query: 403  SASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLH---MAPGAGEHHLARR 459
               +     P    +  +  + G    RR  PG     L    H    +P + +   A  
Sbjct: 2426 PLITMPATRPKPKKARAAEES-GAKGPRR--PGEEAELLVKLDHEGVTSPKSKKAKEALL 2482

Query: 460  VRSDPGGGG-------LAYAAYANGLGAQLP----------------------------- 483
            +R DPG GG       L+  +Y    G+  P                             
Sbjct: 2483 LREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPK 2542

Query: 484  ----------GLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRD 517
                      G + S++S SSSS SSSSSSSSSSSG   +G  +
Sbjct: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEE 2586



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 44/156 (28%), Positives = 60/156 (38%), Gaps = 29/156 (18%)

Query: 364  DPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNAN 423
            D A  P PG       FE S  G P +P  +      +  + SSS    G  +S+ S+++
Sbjct: 2524 DLAQEPGPGLT-----FEDS--GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSS 2576

Query: 424  LGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLP 483
             G                      +   GE    +      G GG   +A ++   +   
Sbjct: 2577 SG----------------------SETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPAS 2614

Query: 484  GLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCS 519
                S +S SSSSSSSSSSSSSSSS      S   S
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2650


>gi|38788243 myosin regulatory light chain interacting protein [Homo
           sapiens]
          Length = 445

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 11/94 (11%)

Query: 481 QLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRD------CSVCFESEVIAALVPCG 534
           Q P   P  +S SS + SS    S   + + ++  R       C VC E E+ +   PCG
Sbjct: 344 QSPSHSPLKSSESSMNCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEEINSTFCPCG 403

Query: 535 HNLFCMECANRICEKSEPECPVCHTAVTQAIRIF 568
           H + C  CA ++       CPVC + V     ++
Sbjct: 404 HTVCCESCAAQL-----QSCPVCRSRVEHVQHVY 432


>gi|223278368 neuralized-like [Homo sapiens]
          Length = 574

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 488 SDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRIC 547
           S   G++ +S  S   S  + GL +  S +C++C+E  V   +  CGH   C  C  R+ 
Sbjct: 492 SSAGGTAPNSPVSLPESPVTPGLGQ-WSDECTICYEHAVDTVIYTCGHMCLCYACGLRLK 550

Query: 548 EKSEPECPVCHTAVTQAIRIF 568
           +     CP+C   +   I+ +
Sbjct: 551 KALHACCPICRRPIKDIIKTY 571


>gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]
          Length = 345

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 66/230 (28%), Positives = 85/230 (36%), Gaps = 50/230 (21%)

Query: 320 PPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQ 379
           PP PA       N     +      GG+A+  +P       P   P P PP G       
Sbjct: 16  PPPPAFKSMEVANFYYEADCLAAAYGGKAAPAAP-------PAARPGPRPPAGELGSIGD 68

Query: 380 FERS--------PGGGPAAPVSSSCSSS--------ASSSASSS------SVVFPG--GG 415
            ER+        P G P AP  ++ + +        A + ASS       S +F    GG
Sbjct: 69  HERAIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSDLFSDDYGG 128

Query: 416 ASAPSNANLGLLVHRR-------LHPGTSCPRLSPP--------LHMAPGAGEHHLARRV 460
            +    A  G +   R       LHPG   P   PP        L   PG       R+ 
Sbjct: 129 KNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPGFEPADCKRKE 188

Query: 461 RSD-PGGGGLAYAAYANGLGAQLPGLQ--PSDTSGSSSSSSSSSSSSSSS 507
            +  PGGG    A +   L A L G Q  PS +SGS S+SSSSS   + S
Sbjct: 189 EAGAPGGGAGMAAGFPYALRAYL-GYQAVPSGSSGSLSTSSSSSPPGTPS 237



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 56/184 (30%), Positives = 69/184 (37%), Gaps = 25/184 (13%)

Query: 344 AGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQ-FERSPGGGPAAPVSSSCSSSASS 402
           AG   S+   +   +  P  +P  AP   AP      FE +P     AP SS       S
Sbjct: 60  AGELGSIGDHERAIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLS 119

Query: 403 SASSSSVVFPGGGASAPSNANLGLLVHRRL-------HPGTSCPRLSPP--------LHM 447
              S       GG +    A  G +   RL       HPG   P   PP        L  
Sbjct: 120 DLFSDDY----GGKNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKA 175

Query: 448 APGAGEHHLARRVRSD-PGGGGLAYAAYANGLGAQLPGLQ--PSDTSGSSSSSSSSSSSS 504
            PG       R+  +  PGGG    A +   L A L G Q  PS +SGS S +SSSSS  
Sbjct: 176 EPGFEPADCKRKEEAGAPGGGAGMAAGFPYALRAYL-GYQAVPSGSSGSLS-TSSSSSPP 233

Query: 505 SSSS 508
            + S
Sbjct: 234 GTPS 237


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 69/279 (24%), Positives = 98/279 (35%), Gaps = 61/279 (21%)

Query: 239  NDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTD 298
            + +  +G+     L HG  GSG G        S +P+ GR    S ++ S S  GS    
Sbjct: 1451 SSYGQHGSGSRQSLGHGQHGSGSGQ-------SPSPSRGRHGSGSGQSSSYSPYGS---- 1499

Query: 299  SYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPE 358
               G G SSS    +  + +S     L    + +  ++G G   ++ G +S     G   
Sbjct: 1500 ---GSGWSSSRGPYESGSSHSS---GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 1553

Query: 359  LQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASA 418
             Q                                SSSC    +SS  SSS    G G+S 
Sbjct: 1554 GQ--------------------------------SSSCGQHGASSGQSSSHGQHGSGSSQ 1581

Query: 419  PSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAA-YANG 477
             S        + R   G+       P H   G+G        R   G G  + +  + +G
Sbjct: 1582 SSG-------YGRQGSGSG----QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 1630

Query: 478  LGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSR 516
            LG          +SG SSS S   S S  SSG  + GSR
Sbjct: 1631 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1669



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 75/284 (26%), Positives = 103/284 (36%), Gaps = 31/284 (10%)

Query: 243  ANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFG 302
            ++G   G+  H    GSG G      + S      R   SS      SS GS+S+    G
Sbjct: 937  SSGQSSGYTQH----GSGSGH-----SSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHG 987

Query: 303  GGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGY-TYTAG-GEASVPSPDGCPELQ 360
             G+  S    Q     S  SP+ S   +G+ +   + Y  Y +G G +S   P       
Sbjct: 988  SGSRQSLGHGQH-GSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH 1046

Query: 361  PTFDPAPAPPPGAPLIWAQFERSPGG-------GPAAPVSSSCSSSASSSASSSSVVFPG 413
             +         G    + Q   S G        G  +  SSSC    +SS  SSS    G
Sbjct: 1047 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1106

Query: 414  GGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAA 473
             G+S  S        + R   G+       P H   G+G        R   G G  + + 
Sbjct: 1107 SGSSQSSG-------YGRQGSGSG----QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG 1155

Query: 474  -YANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSR 516
             + +GLG          +SG SSS S   S S  SSG  + GSR
Sbjct: 1156 QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1199



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 69/279 (24%), Positives = 98/279 (35%), Gaps = 61/279 (21%)

Query: 239  NDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTD 298
            + +  +G+     L HG  GSG G        S +P+ GR    S ++ S S  GS    
Sbjct: 2391 SSYGQHGSGSRQSLGHGQHGSGSGQ-------SPSPSRGRHGSGSGQSSSYSPYGS---- 2439

Query: 299  SYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPE 358
               G G SSS    +  + +S     L    + +  ++G G   ++ G +S     G   
Sbjct: 2440 ---GSGWSSSRGPYESGSGHSS---GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 2493

Query: 359  LQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASA 418
             Q                                SSSC    +SS  SSS    G G+S 
Sbjct: 2494 GQ--------------------------------SSSCGQHGASSGQSSSHGQHGSGSSQ 2521

Query: 419  PSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAA-YANG 477
             S        + R   G+       P H   G+G        R   G G  + +  + +G
Sbjct: 2522 SSG-------YGRQGSGSG----QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 2570

Query: 478  LGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSR 516
            LG          +SG SSS S   S S  SSG  + GSR
Sbjct: 2571 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2609



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 68/286 (23%), Positives = 97/286 (33%), Gaps = 35/286 (12%)

Query: 242  HANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSS------SSLGSA 295
            H +G        H    SG  S +S+       + G     S    SS      SS GS+
Sbjct: 1157 HGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS 1216

Query: 296  STDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDG 355
            S     G G+  S+    R    S  SP+     +G  +++ +G   +  G +S   P  
Sbjct: 1217 SHYGQHGSGSRQSSGHG-RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1275

Query: 356  CPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSS-----CSSSASSSASSSSVV 410
                            G   ++ Q E   G   A     S     CS     S S  S  
Sbjct: 1276 SRS-------------GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST 1322

Query: 411  FPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGG-GL 469
            F   G+S   +++ G       H G+   + S   +   GAG      R R   G G   
Sbjct: 1323 FDQEGSSTGQSSSYG-------HRGSGSSQSSG--YGRHGAGSGQSPSRGRHGSGSGHSS 1373

Query: 470  AYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
            +Y  + +G G      +    SG SS      SSS  SSG  + GS
Sbjct: 1374 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS 1419



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 74/299 (24%), Positives = 111/299 (37%), Gaps = 43/299 (14%)

Query: 244 NGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDS---- 299
           +G+  G    HG  GS  G          + + G+   +S ++ S    GS S+ S    
Sbjct: 600 HGSSSGHSSTHGQHGSTSGQ---------SSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650

Query: 300 YFGGGTSSSAAATQRLADYSPPSP----------ALSFAHNGNNNNNGNGYTYTAG-GEA 348
             G G+  S +  +  +D+   S           + S   +G+ +   +G+ + +G G++
Sbjct: 651 QQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710

Query: 349 SVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSS 408
           S  S  G      +         G      Q  RS   G ++ +SSS     S S  SS 
Sbjct: 711 SGYSQHGSGSSHSSGYRKHGSRSG------QSSRSEQHGSSSGLSSSYGQHGSGSHQSSG 764

Query: 409 VVFPGGGAS-APSNANLGLLV-----HRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRS 462
               G G+  +PS    G        H +   GTSC   S   H   G+G+   A     
Sbjct: 765 HGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS--SSCGHYESGSGQ---ASGFGQ 819

Query: 463 DPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSS--SSSSSSSSSGLRRKGSRDCS 519
              G G  Y+ + +  G      +   TSG SSSS    SSS  SSS G     S   S
Sbjct: 820 HESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHAS 878



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 70/299 (23%), Positives = 96/299 (32%), Gaps = 46/299 (15%)

Query: 244  NGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGG 303
            +G+ +G    HG  GSG G   S+      P   R   SS      S  G +S  S  G 
Sbjct: 1718 HGSGLGHSSSHGQHGSGSGRSSSRG-----PYESRSGHSSVFGQHESGSGHSSAYSQHGS 1772

Query: 304  GTS--------SSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDG 355
            G+          S +      D    S   S +H  + + +    +Y   G  S  SP  
Sbjct: 1773 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSR 1832

Query: 356  CPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGG 415
                  +   +     G+   W+      G G     SS      SSS  SS     G G
Sbjct: 1833 GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ--SSGFGHHESSSWQSSGYTQHGSG 1890

Query: 416  ASAPSN-----ANLGLLVHRRLHPGTSCPRLSPPLHMA------------PGAGEHHLAR 458
            +   S+     +  G       H  +S    S   H +             G+G+     
Sbjct: 1891 SGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1950

Query: 459  RVRSDPGGG-GLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSR 516
            R R   G G   +Y  Y +G             SG SSS     S S  SSGL  + SR
Sbjct: 1951 RGRHGSGSGQSSSYGPYGSG-------------SGWSSSRGPYESGSGHSSGLGHRESR 1996



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 80/316 (25%), Positives = 107/316 (33%), Gaps = 47/316 (14%)

Query: 244  NGTDVGFDLHHGSGGSGPG----SLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDS 299
            +G   GF  H  S     G       S  + S      R   SS      SS GS+S+  
Sbjct: 1865 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYG 1924

Query: 300  YFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGY-TYTAG-GEASVPSPDGCP 357
              G G+  S    Q     S  SP+ S   +G+ +   + Y  Y +G G +S   P    
Sbjct: 1925 QHGSGSRQSLGHGQH-GSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESG 1983

Query: 358  ELQPTFDPAPAPPPGAPLIWAQFERSPGG-------GPAAPVSSSCSSSASSSASSSSVV 410
                +         G    + Q   S G        G A+  SSSC    +SS  SSS  
Sbjct: 1984 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG 2043

Query: 411  FPGGGAS--------------APSNANLGLLVHRRLHP-----GTSCPRLSPPLHMAPGA 451
              G G+S              +P +   G     R  P     G+   R S      PG 
Sbjct: 2044 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGS--GSRQSPSYGRHGSGSGRSSSSGQHGPGL 2101

Query: 452  GE-----HHLARRVRSDP-------GGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSS 499
            GE     HH +   +S          G    Y  + +  G    G +   +SGSSS    
Sbjct: 2102 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ 2161

Query: 500  SSSSSSSSSGLRRKGS 515
              S S  SSG  R+GS
Sbjct: 2162 HGSGSRQSSGHGRQGS 2177



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 67/294 (22%), Positives = 98/294 (33%), Gaps = 45/294 (15%)

Query: 241  FHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSY 300
            F   G+  G    HG  GSG     S  + S          S  R    S  G +S+   
Sbjct: 1793 FDQEGSSTGQSSSHGQHGSG-----SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 1847

Query: 301  FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTY--TAGGEASVPSPDGCPE 358
             G G+  S+++ +  +     S    F H+ +++   +GYT   +  G +S     G   
Sbjct: 1848 HGSGSGWSSSSGRHGSGSGQSS---GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 1904

Query: 359  LQPTFDPAPAPPPGAPLIWAQF-----------ERSPGGGPAAPVSSSCSSSASSSASSS 407
             Q +         G+   + Q            +   G G +   S     S S  +SS 
Sbjct: 1905 GQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1964

Query: 408  SVVFPGGGASA---PSNANLGL---LVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVR 461
                 G G S+   P  +  G    L HR    G S            G G+H       
Sbjct: 1965 GPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS-----------GYGQH------- 2006

Query: 462  SDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
                G    +  + +  G      Q   +SG SSS     S SS SSG  R+GS
Sbjct: 2007 GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 68/291 (23%), Positives = 92/291 (31%), Gaps = 30/291 (10%)

Query: 244  NGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGG 303
            +G+  G    HG  GSG G   S+      P   R   SS      S  G +S  S  G 
Sbjct: 2188 HGSGSGHSSSHGQHGSGSGRSSSRG-----PYESRSGHSSVFGQHESGSGHSSAYSQHGS 2242

Query: 304  GTS--------SSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDG 355
            G+          S +      D    S   S +H  + + +    +Y   G  S  SP  
Sbjct: 2243 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSR 2302

Query: 356  CPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGG 415
                  +   +     G+   W+      G G     SS      SSS  SS     G G
Sbjct: 2303 GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ--SSGFGHHESSSWQSSGYTQHGSG 2360

Query: 416  ASAPSN-----ANLGLLVHRRLHPGTSCPRLSPPLH-----MAPGAGEHHLARRVRSDPG 465
            +   S+     +  G       H  +S    S   H      + G G+H         P 
Sbjct: 2361 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 2420

Query: 466  GGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSR 516
             G      + +G G           SG SSS     S S  SSGL  + SR
Sbjct: 2421 RG-----RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESR 2466



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 67/288 (23%), Positives = 96/288 (33%), Gaps = 44/288 (15%)

Query: 239 NDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTD 298
           + +  +G+     L HG  GSG     S+ +PS      R    S  + S    GS S+ 
Sbjct: 281 SSYGQHGSGSRQSLGHGRQGSG-----SRQSPSHV----RHGSGSGHSSSHGQHGSGSSY 331

Query: 299 SYFGGGTSSSAAATQRLADY---SPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDG 355
           SY  G   S +  T     +   S  S   S   +G+ +++  G   +  G+AS     G
Sbjct: 332 SYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHG 391

Query: 356 CPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPG-- 413
               Q +              + Q E           S+S  SS     SS S   PG  
Sbjct: 392 SSSRQSSS-------------YGQHE-----------SASRHSSGRGQHSSGSGQSPGHG 427

Query: 414 ----GGASAPSNANLGLLVHRRLHPG--TSCPRLSPPLHMAPGAGEHHLARRVRSDPGGG 467
               G   +PS+   G    R    G   S    S        + EH           G 
Sbjct: 428 QRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487

Query: 468 GLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
              +  + +  G    G +   ++GSSSS     S S  S G  R GS
Sbjct: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGS 535



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 61/277 (22%), Positives = 91/277 (32%), Gaps = 24/277 (8%)

Query: 241  FHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSY 300
            F   G+  G    HG  GSG     S  + S          S  R    S  G +S+   
Sbjct: 2263 FDQEGSSTGQSSSHGQHGSG-----SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 2317

Query: 301  FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTY--TAGGEASVPSPDGCPE 358
             G G+  S+++ +  +     S    F H+ +++   +GYT   +  G +S     G   
Sbjct: 2318 HGSGSGWSSSSGRHGSGSGQSS---GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 2374

Query: 359  LQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASA 418
             Q +         G+   + Q     G G    +      S S  + S S    G G+  
Sbjct: 2375 GQSSRGERHGSSSGSSSSYGQH----GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 2430

Query: 419  PSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGL 478
             S+       +     G+       P     G       R  RS    G   Y  + +  
Sbjct: 2431 SSS-------YSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG---YGQHGSSS 2480

Query: 479  GAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
            G      Q   TSG SSS     +SS  SS   + GS
Sbjct: 2481 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 2517



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 69/285 (24%), Positives = 101/285 (35%), Gaps = 58/285 (20%)

Query: 236  TDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSA 295
            +  + +   G+  G    HG  GSG     S+ +PS     GR    S R+ SS   GS 
Sbjct: 1110 SQSSGYGRQGSGSGQSPGHGQRGSG-----SRQSPSY----GRHGSGSGRSSSSGQHGSG 1160

Query: 296  STDSY-FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPD 354
              +S  FG   SSS  ++             S++ +G+ + + +GY     G+    S  
Sbjct: 1161 LGESSGFGHHESSSGQSS-------------SYSQHGSGSGHSSGY-----GQHGSRS-- 1200

Query: 355  GCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGG 414
                                    Q  R    G ++  SS      S S  SS     G 
Sbjct: 1201 -----------------------GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 1237

Query: 415  GAS-APSNANLGL-LVHRRLHP--GTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLA 470
            G+  +PS    G  L H   H   G+   R S        +G   +  +  S  G    A
Sbjct: 1238 GSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS-A 1296

Query: 471  YAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
            Y+ + +G G      Q   TSG SS+     SS+  SS    +GS
Sbjct: 1297 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 1341



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 70/275 (25%), Positives = 91/275 (33%), Gaps = 27/275 (9%)

Query: 244 NGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGG 303
           +G+  G    +G  GSG  S  S          G  P S  R+ SSS  G +S+    G 
Sbjct: 742 HGSSSGLSSSYGQHGSG--SHQSSGHGRQGSGSGHSP-SRVRHGSSS--GHSSSHGQHGS 796

Query: 304 GTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTF 363
           GTS S++        S    A  F  + + +  G     +A G  S     G    Q + 
Sbjct: 797 GTSCSSSCGHY---ESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853

Query: 364 DPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNAN 423
                   G    + Q E           S+S  +S      S S   PG G     +  
Sbjct: 854 SGQHDSSSGQSSSYGQHE-----------SASHHASGRGRHGSGSGQSPGHGQRGSGS-- 900

Query: 424 LGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLP 483
            G       H   S    S   H   G+G    +        G    Y  + +G G    
Sbjct: 901 -GQSPSYGRHGSGSGRSSSSGRH---GSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956

Query: 484 GLQPSDTSGSSSSSSS--SSSSSSSSSGLRRKGSR 516
             Q    SG SS S    SSS SSSS G    GSR
Sbjct: 957 YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSR 991



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 69/285 (24%), Positives = 100/285 (35%), Gaps = 58/285 (20%)

Query: 236  TDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSA 295
            +  + +   G+  G    HG  GSG     S+ +PS     GR    S R+ SS   GS 
Sbjct: 2520 SQSSGYGRQGSGSGQSPGHGQRGSG-----SRQSPSY----GRHGSGSGRSSSSGQHGSG 2570

Query: 296  STDSY-FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPD 354
              +S  FG   SSS  ++             S++ +G+ + + +GY     G+    S  
Sbjct: 2571 LGESSGFGHHESSSGQSS-------------SYSQHGSGSGHSSGY-----GQHGSRS-- 2610

Query: 355  GCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGG 414
                                    Q  R    G ++  SS      S S  SS     G 
Sbjct: 2611 -----------------------GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 2647

Query: 415  GAS-APSNANLGL-LVHRRLHP--GTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLA 470
            G+  +PS    G  L H   H   G+   R S         G   +  +  S  G    A
Sbjct: 2648 GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSS-A 2706

Query: 471  YAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
            Y+ + +G G      Q   TSG SS+     SS+  SS    +GS
Sbjct: 2707 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 72/291 (24%), Positives = 103/291 (35%), Gaps = 60/291 (20%)

Query: 236  TDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSA 295
            +  + +   G+  G    HG  GSG     S+ +PS     GR    S R+ SS   GS 
Sbjct: 1580 SQSSGYGRQGSGSGQSPGHGQRGSG-----SRQSPSY----GRHGSGSGRSSSSGQHGSG 1630

Query: 296  STDSY-FGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPD 354
              +S  FG   SSS  ++             S++ +G+ + + +GY     G+    S  
Sbjct: 1631 LGESSGFGHHESSSGQSS-------------SYSQHGSGSGHSSGY-----GQHGSRS-- 1670

Query: 355  GCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGG 414
                                    Q  R    G ++  SS      S S  SS     G 
Sbjct: 1671 -----------------------GQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGS 1707

Query: 415  GAS-APSNANLGL-LVHRRLHP--GTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLA 470
            G+  +PS    G  L H   H   G+   R S        +G   +  +  S  G    A
Sbjct: 1708 GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS-A 1766

Query: 471  YAAYANGLGAQLPGLQPSDTSGSSSS--SSSSSSSSSSSSGLRRKGSRDCS 519
            Y+ + +G G      Q   TSG SS+     SS+  SSS G    GS   S
Sbjct: 1767 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 1817



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 61/274 (22%), Positives = 89/274 (32%), Gaps = 51/274 (18%)

Query: 244  NGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGG 303
            +G+  G    HG  GSG G          +P+ GR    S R+ SS   GS S  S   G
Sbjct: 883  HGSGSGQSPGHGQRGSGSGQ---------SPSYGRHGSGSGRSSSSGRHGSGSGQSSGFG 933

Query: 304  GTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTY--TAGGEASVPSPDGCPELQP 361
              SSS  ++              +  +G+ + + + Y    +  G++S     G      
Sbjct: 934  HKSSSGQSS-------------GYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSS--- 977

Query: 362  TFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSN 421
                      G+   + Q     G G    +      S S  + S S    G G+   S+
Sbjct: 978  ----------GSSSSYGQH----GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023

Query: 422  ANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQ 481
                   +     G+       P     G       R  RS    G   Y  + +  G  
Sbjct: 1024 -------YGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG---YGQHGSSSGHS 1073

Query: 482  LPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
                Q   TSG SSS     +SS  SS   + GS
Sbjct: 1074 STHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1107



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 64/280 (22%), Positives = 96/280 (34%), Gaps = 68/280 (24%)

Query: 278 RKPFSSYRND---SSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNN 334
           ++ FS   N     SSS G  ++DS+   G     + + +  +Y         + + + +
Sbjct: 162 QRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTH 221

Query: 335 NNGNGYTY------TAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGP 388
            +G+G +       ++ G++S  S  G                G    + Q       G 
Sbjct: 222 GSGSGQSSGFSQHKSSSGQSSGYSQHGSGS-------------GHSSGYGQH------GS 262

Query: 389 AAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMA 448
            +  SS      SSS SSSS    G G    S  +LG   H R   G+       P H+ 
Sbjct: 263 RSGQSSRGERHRSSSGSSSSYGQHGSG----SRQSLG---HGRQGSGSR----QSPSHVR 311

Query: 449 PGAGEHHLARRVRSDPG---------------------------GGGLAYAAYANGLGAQ 481
            G+G  H +   +   G                           G    Y+ + +G G  
Sbjct: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371

Query: 482 LPGLQPSDTSGSSSSSS--SSSSSSSSSSGLRRKGSRDCS 519
               Q   TSG +SSS    SSS  SSS G     SR  S
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSS 411



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 62/281 (22%), Positives = 92/281 (32%), Gaps = 30/281 (10%)

Query: 244  NGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGG 303
            +G   G    HG  GSG          S +   GR+   S ++      GS S  S   G
Sbjct: 2032 HGASSGQSSSHGQHGSGS---------SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 2082

Query: 304  GTSSSAAATQRLADYSPP-SPALSFAHNGNNNNNGNGYTY--TAGGEASVPSPDGCPELQ 360
               S +  +     + P    +  F H+ +++   + Y+   +  G +S     G    Q
Sbjct: 2083 RHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 2142

Query: 361  PTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPS 420
             +         G+   + Q       G  +  SS      S S  S S    G G+   S
Sbjct: 2143 SSRGERHGSSSGSSSRYGQH------GSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSS 2196

Query: 421  NANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGA 480
            +       H +   G+       P     G   H           G   AY+ + +G G 
Sbjct: 2197 S-------HGQHGSGSGRSSSRGPYESRSG---HSSVFGQHESGSGHSSAYSQHGSGSGH 2246

Query: 481  QLPGLQPSDTSGSSSS--SSSSSSSSSSSSGLRRKGSRDCS 519
                 Q   TSG SS+     SS+  SSS G    GS   S
Sbjct: 2247 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 2287



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 64/280 (22%), Positives = 99/280 (35%), Gaps = 48/280 (17%)

Query: 242  HANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDS----SSSLGSAST 297
            H +G+  G+  H  + G          T   + + G+   SS ++ S     S+   AS 
Sbjct: 820  HESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASG 879

Query: 298  DSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCP 357
                G G+  S    QR    S  SP+     +G+  ++ +G   +  G++S     G  
Sbjct: 880  RGRHGSGSGQSPGHGQR-GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSS-----GFG 933

Query: 358  ELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGAS 417
                +   +     G+           G G ++      S S  SS S         G+S
Sbjct: 934  HKSSSGQSSGYTQHGS-----------GSGHSSSYEQHGSRSGQSSRSEQH------GSS 976

Query: 418  APSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGG-GLAYAAYAN 476
            + S+++ G       H   S   L    H   G+G+     R R   G G   +Y  Y +
Sbjct: 977  SGSSSSYGQ------HGSGSRQSLGHGQH-GSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029

Query: 477  GLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSR 516
            G             SG SSS     S S  SSGL  + SR
Sbjct: 1030 G-------------SGWSSSRGPYESGSGHSSGLGHRESR 1056



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 62/279 (22%), Positives = 92/279 (32%), Gaps = 31/279 (11%)

Query: 254 HGS-----GGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSS 308
           HGS       SG     S+ + S          SS R   SS  G +      G G+  S
Sbjct: 377 HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQS 436

Query: 309 AAATQRLADY---SPPSPALS-------FAHNGNNNNNGNGYTY--TAGGEASVPSPDGC 356
            ++ Q    +   S   P +S       F H+ +++ + +GYT   +  G +S     G 
Sbjct: 437 PSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGS 496

Query: 357 PELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGA 416
              Q +         G+   + Q     G G    +  S   S S  + S S     G  
Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQH----GSGSRQSLGHSRHGSGSGQSPSPS----RGRH 548

Query: 417 SAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYAN 476
            + S  +     H     G    R S       G+G H      +    G    Y  + +
Sbjct: 549 ESGSRQSSSYGPH-----GYGSGRSSSRGPYESGSG-HSSGLGHQESRSGQSSGYGQHGS 602

Query: 477 GLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGS 515
             G      Q   TSG SSS     ++S  SS   + GS
Sbjct: 603 SSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGS 641


>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
           sapiens]
          Length = 731

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 49/190 (25%), Positives = 74/190 (38%), Gaps = 27/190 (14%)

Query: 382 RSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRL 441
           R  G G A     S ++S+ +SASSS        +S+PS  ++ +     +  G +    
Sbjct: 5   RQAGSGSAGTSPGSSAASSVTSASSSL-------SSSPSPPSVAVSAAALVSGGVA---- 53

Query: 442 SPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSS 501
                 A   G     R V   P   G    A + GL       +PS   G SSSS  S 
Sbjct: 54  ----QAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSG 109

Query: 502 S----------SSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSE 551
           S          +   +S   +     C +CF+    A +  CGH+ FC +C ++  E + 
Sbjct: 110 SRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHS-FCYKCIHQSLEDNN 168

Query: 552 PECPVCHTAV 561
             CP C+  V
Sbjct: 169 -RCPKCNYVV 177


>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
           sapiens]
          Length = 707

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 49/190 (25%), Positives = 74/190 (38%), Gaps = 27/190 (14%)

Query: 382 RSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRL 441
           R  G G A     S ++S+ +SASSS        +S+PS  ++ +     +  G +    
Sbjct: 5   RQAGSGSAGTSPGSSAASSVTSASSSL-------SSSPSPPSVAVSAAALVSGGVA---- 53

Query: 442 SPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSS 501
                 A   G     R V   P   G    A + GL       +PS   G SSSS  S 
Sbjct: 54  ----QAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSG 109

Query: 502 S----------SSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSE 551
           S          +   +S   +     C +CF+    A +  CGH+ FC +C ++  E + 
Sbjct: 110 SRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHS-FCYKCIHQSLEDNN 168

Query: 552 PECPVCHTAV 561
             CP C+  V
Sbjct: 169 -RCPKCNYVV 177


>gi|55953110 retinoblastoma protein-binding zinc finger protein
           isoform c [Homo sapiens]
          Length = 1481

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 50/151 (33%), Positives = 67/151 (44%), Gaps = 10/151 (6%)

Query: 260 GPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYS 319
           GPGS +  P P++  TP   P S      S S G            SS       L   +
Sbjct: 727 GPGSGF--PAPTVESTPDVCPSSPALQTPSLSSGQLPP-LLIPTDPSSPPPCPPVLTVAT 783

Query: 320 PPSPALSFAHNGNNNNNGNGYTYTAG-GEASVPSPDGCPELQPTFDPAPAP-PPGAPLIW 377
           PP P L        +++ + +   +    A+  SP   P L PT  P+P+P PP  PL+ 
Sbjct: 784 PPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQSP--LPILSPTVSPSPSPIPPVEPLMS 841

Query: 378 AQFERSPGGGPAAPVSSSCSSSASSSASSSS 408
           A    SPG    +  SSS SSS+S S+SSSS
Sbjct: 842 A---ASPGPPTLSSSSSSSSSSSSFSSSSSS 869



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 62/233 (26%), Positives = 75/233 (32%), Gaps = 60/233 (25%)

Query: 276 PGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNN 335
           P   P    R+ S      A  D   G G+   A   +   D  P SPAL          
Sbjct: 701 PVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQ--------- 751

Query: 336 NGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSS 395
                        S+ S    P L PT    P+ PP  P +       P   P  P+ + 
Sbjct: 752 -----------TPSLSSGQLPPLLIPT---DPSSPPPCPPVLTVATPPPPLLPTVPLPAP 797

Query: 396 CSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHH 455
                SSSAS      P   A+A S                  P LSP +  +P      
Sbjct: 798 -----SSSASPHPCPSPLSNATAQS----------------PLPILSPTVSPSPSPIPPV 836

Query: 456 LARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSS 508
                 + PG                 P L  S +S SSSSS SSSSSSSS S
Sbjct: 837 EPLMSAASPGP----------------PTLSSSSSSSSSSSSFSSSSSSSSPS 873


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,936,548
Number of Sequences: 37866
Number of extensions: 1697938
Number of successful extensions: 22893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 784
Number of HSP's that attempted gapping in prelim test: 14356
Number of HSP's gapped (non-prelim): 6285
length of query: 569
length of database: 18,247,518
effective HSP length: 108
effective length of query: 461
effective length of database: 14,157,990
effective search space: 6526833390
effective search space used: 6526833390
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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