Search of human proteins with 4759248

Search of human proteins with 4759248

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]
         (444 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]                    905   0.0  
gi|31795563 tryptophan hydroxylase 2 [Homo sapiens]                   677   0.0  
gi|4557819 phenylalanine hydroxylase [Homo sapiens]                   492   e-139
gi|88900505 tyrosine hydroxylase isoform c [Homo sapiens]             434   e-122
gi|88900501 tyrosine hydroxylase isoform a [Homo sapiens]             434   e-122
gi|88900503 tyrosine hydroxylase isoform b [Homo sapiens]             434   e-122
gi|40807489 egf-like module containing, mucin-like, hormone rece...    33   0.40 
gi|51988900 XPG-complementing protein [Homo sapiens]                   32   1.5  
gi|30794488 kinesin family member 27 [Homo sapiens]                    32   1.5  
gi|15011918 ATPase, H+ transporting, lysosomal accessory protein...    30   3.4  
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    30   3.4  
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    30   3.4  
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    30   3.4  
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    30   3.4  
gi|209413766 zinc finger and BTB domain containing 43 [Homo sapi...    30   3.4  
gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]     30   3.4  
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ...    30   5.8  
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]       30   5.8  
gi|239753110 PREDICTED: doublecortin domain-containing protein E...    30   5.8  
gi|239747673 PREDICTED: doublecortin domain-containing protein E...    30   5.8  
gi|239741542 PREDICTED: doublecortin domain-containing protein E...    30   5.8  
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          29   7.5  
gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]      29   9.8  
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]        29   9.8  
gi|239752250 PREDICTED: similar to acetylserotonin O-methyltrans...    29   9.8  
gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo s...    29   9.8  
gi|21686971 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-ace...    29   9.8  
gi|29570788 CSRP2 binding protein isoform b [Homo sapiens]             29   9.8  
gi|24308203 CSRP2 binding protein isoform a [Homo sapiens]             29   9.8  

>gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]
          Length = 444

 Score =  905 bits (2340), Expect = 0.0
 Identities = 444/444 (100%), Positives = 444/444 (100%)

Query: 1   MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF 60
           MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF
Sbjct: 1   MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF 60

Query: 61  EIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCAN 120
           EIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCAN
Sbjct: 61  EIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCAN 120

Query: 121 RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQE 180
           RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQE
Sbjct: 121 RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQE 180

Query: 181 LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD 240
           LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
Sbjct: 181 LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD 240

Query: 241 FLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA 300
           FLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
Sbjct: 241 FLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA 300

Query: 301 SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITC 360
           SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITC
Sbjct: 301 SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITC 360

Query: 361 KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA 420
           KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA
Sbjct: 361 KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA 420

Query: 421 MNELQHDLDVVSDALAKVSRKPSI 444
           MNELQHDLDVVSDALAKVSRKPSI
Sbjct: 421 MNELQHDLDVVSDALAKVSRKPSI 444


>gi|31795563 tryptophan hydroxylase 2 [Homo sapiens]
          Length = 490

 Score =  677 bits (1747), Expect = 0.0
 Identities = 317/442 (71%), Positives = 382/442 (86%), Gaps = 5/442 (1%)

Query: 4   DNKENKDHS-----LERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNS 58
           D+K NK  S      E G+ +++FSLKNEVGGL+KAL++FQEK VN++HIESRKS+RR+S
Sbjct: 45  DDKGNKGSSKREAATESGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSS 104

Query: 59  EFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHC 118
           E EIFVDC+  + + N++  LLK  T ++++N P+N   +E+ +E VPWFP+KIS+LD C
Sbjct: 105 EVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKC 164

Query: 119 ANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVF 178
           ++RVLMYGSELDADHPGFKDNVYR+RRKYF D+AM YK+G PIP+VE+TEEE KTWG VF
Sbjct: 165 SHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVF 224

Query: 179 QELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSP 238
           +EL+KLYPTHACREYLKN PLL+KYCGYREDN+PQLEDVS FLKER+GF++RPVAGYLSP
Sbjct: 225 RELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSP 284

Query: 239 RDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASL 298
           RDFL+GLA+RVFHCTQY+RH SDP YTPEPDTCHELLGHVPLLA+P FAQFSQEIGLASL
Sbjct: 285 RDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASL 344

Query: 299 GASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKI 358
           GAS+E VQKLATCYFFT+EFGLCKQ+GQLR +GAGLLSSI ELKHALS  A VK FDPK 
Sbjct: 345 GASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKT 404

Query: 359 TCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSIT 418
           TC QECLITTFQ+ YFVSESFE+AKEKMR+F K+I RPF V +NPYT+SI+ILKDT+SI 
Sbjct: 405 TCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIE 464

Query: 419 SAMNELQHDLDVVSDALAKVSR 440
           + + +L+ DL+ V DAL K+++
Sbjct: 465 NVVQDLRSDLNTVCDALNKMNQ 486


>gi|4557819 phenylalanine hydroxylase [Homo sapiens]
          Length = 452

 Score =  492 bits (1266), Expect = e-139
 Identities = 239/430 (55%), Positives = 308/430 (71%), Gaps = 4/430 (0%)

Query: 9   KDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDI 68
           +D+  + G  SLIFSLK EVG L K L++F+E  VNL HIESR S+ +  E+E F   D 
Sbjct: 26  EDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFFTHLD- 84

Query: 69  NREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSE 128
            +  L  + +++K   + +   + +    ++   +TVPWFP+ I +LD  AN++L YG+E
Sbjct: 85  -KRSLPALTNIIKILRHDIGATVHE--LSRDKKKDTVPWFPRTIQELDRFANQILSYGAE 141

Query: 129 LDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTH 188
           LDADHPGFKD VYR RRK FAD+A NY+HG PIP+VE+ EEE KTWGTVF+ L  LY TH
Sbjct: 142 LDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTH 201

Query: 189 ACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFR 248
           AC EY    PLL KYCG+ EDNIPQLEDVS FL+  TGF +RPVAG LS RDFL GLAFR
Sbjct: 202 ACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFR 261

Query: 249 VFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKL 308
           VFHCTQY+RH S P YTPEPD CHELLGHVPL ++ SFAQFSQEIGLASLGA +E ++KL
Sbjct: 262 VFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKL 321

Query: 309 ATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITT 368
           AT Y+FTVEFGLCKQ   ++ +GAGLLSS  EL++ LS   K+ P + + T  Q   +T 
Sbjct: 322 ATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTE 381

Query: 369 FQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDL 428
           FQ +Y+V+ESF DAKEK+R F  TI RPF V+Y+PYT+ I++L +T+ +    + +  ++
Sbjct: 382 FQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEI 441

Query: 429 DVVSDALAKV 438
            ++  AL K+
Sbjct: 442 GILCSALQKI 451


>gi|88900505 tyrosine hydroxylase isoform c [Homo sapiens]
          Length = 524

 Score =  434 bits (1117), Expect = e-122
 Identities = 213/424 (50%), Positives = 293/424 (69%), Gaps = 14/424 (3%)

Query: 19  SLIFSLK-NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNS---EFEIFVDCDINREQLN 74
           +L+FS +  +   L +A+K+F+     + H+E+R ++R  +     E FV  ++ R    
Sbjct: 110 NLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRR---G 166

Query: 75  DIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHP 134
           D+  LL     V          ++      VPWFP+K+S+LD C + V  +  +LD DHP
Sbjct: 167 DLAALLSGVRQVSE-------DVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHP 219

Query: 135 GFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYL 194
           GF D VYR+RRK  A++A  Y+HGDPIP+VE+T EEI TW  V+  L  LY THAC E+L
Sbjct: 220 GFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHL 279

Query: 195 KNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQ 254
           +   LL ++ GYREDNIPQLEDVS FLKERTGF +RPVAG LS RDFL+ LAFRVF CTQ
Sbjct: 280 EAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQ 339

Query: 255 YVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFF 314
           Y+RH+S P ++PEPD CHELLGHVP+LA+ +FAQFSQ+IGLASLGAS+E ++KL+T Y+F
Sbjct: 340 YIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWF 399

Query: 315 TVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYF 374
           TVEFGLCKQ+G+++ +GAGLLSS  EL H LS   +++ FDP+    Q     T+Q VYF
Sbjct: 400 TVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYF 459

Query: 375 VSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDA 434
           VSESF DAK+K+R +   I+RPF VK++PYT +I +L   +++  ++  +Q +LD ++ A
Sbjct: 460 VSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHA 519

Query: 435 LAKV 438
           L+ +
Sbjct: 520 LSAI 523


>gi|88900501 tyrosine hydroxylase isoform a [Homo sapiens]
          Length = 528

 Score =  434 bits (1117), Expect = e-122
 Identities = 213/424 (50%), Positives = 293/424 (69%), Gaps = 14/424 (3%)

Query: 19  SLIFSLK-NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNS---EFEIFVDCDINREQLN 74
           +L+FS +  +   L +A+K+F+     + H+E+R ++R  +     E FV  ++ R    
Sbjct: 114 NLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRR---G 170

Query: 75  DIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHP 134
           D+  LL     V          ++      VPWFP+K+S+LD C + V  +  +LD DHP
Sbjct: 171 DLAALLSGVRQVSE-------DVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHP 223

Query: 135 GFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYL 194
           GF D VYR+RRK  A++A  Y+HGDPIP+VE+T EEI TW  V+  L  LY THAC E+L
Sbjct: 224 GFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHL 283

Query: 195 KNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQ 254
           +   LL ++ GYREDNIPQLEDVS FLKERTGF +RPVAG LS RDFL+ LAFRVF CTQ
Sbjct: 284 EAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQ 343

Query: 255 YVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFF 314
           Y+RH+S P ++PEPD CHELLGHVP+LA+ +FAQFSQ+IGLASLGAS+E ++KL+T Y+F
Sbjct: 344 YIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWF 403

Query: 315 TVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYF 374
           TVEFGLCKQ+G+++ +GAGLLSS  EL H LS   +++ FDP+    Q     T+Q VYF
Sbjct: 404 TVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYF 463

Query: 375 VSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDA 434
           VSESF DAK+K+R +   I+RPF VK++PYT +I +L   +++  ++  +Q +LD ++ A
Sbjct: 464 VSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHA 523

Query: 435 LAKV 438
           L+ +
Sbjct: 524 LSAI 527


>gi|88900503 tyrosine hydroxylase isoform b [Homo sapiens]
          Length = 497

 Score =  434 bits (1117), Expect = e-122
 Identities = 213/424 (50%), Positives = 293/424 (69%), Gaps = 14/424 (3%)

Query: 19  SLIFSLK-NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNS---EFEIFVDCDINREQLN 74
           +L+FS +  +   L +A+K+F+     + H+E+R ++R  +     E FV  ++ R    
Sbjct: 83  NLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRR---G 139

Query: 75  DIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHP 134
           D+  LL     V          ++      VPWFP+K+S+LD C + V  +  +LD DHP
Sbjct: 140 DLAALLSGVRQVSE-------DVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHP 192

Query: 135 GFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYL 194
           GF D VYR+RRK  A++A  Y+HGDPIP+VE+T EEI TW  V+  L  LY THAC E+L
Sbjct: 193 GFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHL 252

Query: 195 KNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQ 254
           +   LL ++ GYREDNIPQLEDVS FLKERTGF +RPVAG LS RDFL+ LAFRVF CTQ
Sbjct: 253 EAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQ 312

Query: 255 YVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFF 314
           Y+RH+S P ++PEPD CHELLGHVP+LA+ +FAQFSQ+IGLASLGAS+E ++KL+T Y+F
Sbjct: 313 YIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWF 372

Query: 315 TVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYF 374
           TVEFGLCKQ+G+++ +GAGLLSS  EL H LS   +++ FDP+    Q     T+Q VYF
Sbjct: 373 TVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYF 432

Query: 375 VSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDA 434
           VSESF DAK+K+R +   I+RPF VK++PYT +I +L   +++  ++  +Q +LD ++ A
Sbjct: 433 VSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHA 492

Query: 435 LAKV 438
           L+ +
Sbjct: 493 LSAI 496


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 13/92 (14%)

Query: 256 VRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKL------- 308
           V   +DP   PE  TC+  +G+      P F   S  +    L AS E + +        
Sbjct: 173 VDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPIN 232

Query: 309 ATC------YFFTVEFGLCKQDGQLRVFGAGL 334
           +TC      YF T   G    +GQL     G+
Sbjct: 233 STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGV 264


>gi|51988900 XPG-complementing protein [Homo sapiens]
          Length = 1186

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 19/73 (26%), Positives = 32/73 (43%)

Query: 3    EDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEI 62
            ED K  K   L R    ++   K      I+A+ +  EK   LL    RK+++R     +
Sbjct: 1005 EDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTL 1064

Query: 63   FVDCDINREQLND 75
                 + R++L+D
Sbjct: 1065 EESSSLKRKRLSD 1077


>gi|30794488 kinesin family member 27 [Homo sapiens]
          Length = 1401

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 8/91 (8%)

Query: 355 DPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDT 414
           D KI C QE      Q +        +AK+KMRE T  IK    +K +     I+   D 
Sbjct: 695 DLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIK----MKEDLIKELIKTGNDA 750

Query: 415 KSITS----AMNELQHDLDVVSDALAKVSRK 441
           KS++      + +L+HD +     L +  ++
Sbjct: 751 KSVSKQYSLKVTKLEHDAEQAKVELIETQKQ 781


>gi|15011918 ATPase, H+ transporting, lysosomal accessory protein 2
           [Homo sapiens]
          Length = 350

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 18/118 (15%)

Query: 4   DNKENKDHSLERGRASLIFSL---KNEVGGLIKALKIFQEKHVNLLHIESR--------- 51
           D+  N  HSL      ++  L   +  V  + KA  +F++  V L  + +R         
Sbjct: 107 DSVANSIHSLFSEETPVVLQLAPSEERVYMVGKANSVFEDLSVTLRQLRNRLFQENSVLS 166

Query: 52  ----KSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETV 105
                S  RN+E ++    ++  + L+DI  LL  H ++   + PD ++L+  G++ +
Sbjct: 167 SLPLNSLSRNNEVDLLFLSEL--QVLHDISSLLSRHKHLAKDHSPDLYSLELAGLDEI 222


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 23/81 (28%)

Query: 158 GDPIPKV------EFTEEEIKTWGTV-----FQELNKLYPTHACREYLKNLPLLS---KY 203
           G P P+V      EF + EI TW +      +  L KLY    C +Y+K+  +L    K 
Sbjct: 500 GPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKK 559

Query: 204 CG---------YREDNIPQLE 215
           CG         YR++NI   E
Sbjct: 560 CGWFHPPANEIYRKNNISVFE 580


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 23/81 (28%)

Query: 158 GDPIPKV------EFTEEEIKTWGTV-----FQELNKLYPTHACREYLKNLPLLS---KY 203
           G P P+V      EF + EI TW +      +  L KLY    C +Y+K+  +L    K 
Sbjct: 500 GPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKK 559

Query: 204 CG---------YREDNIPQLE 215
           CG         YR++NI   E
Sbjct: 560 CGWFHPPANEIYRKNNISVFE 580


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 23/81 (28%)

Query: 158 GDPIPKV------EFTEEEIKTWGTV-----FQELNKLYPTHACREYLKNLPLLS---KY 203
           G P P+V      EF + EI TW +      +  L KLY    C +Y+K+  +L    K 
Sbjct: 500 GPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKK 559

Query: 204 CG---------YREDNIPQLE 215
           CG         YR++NI   E
Sbjct: 560 CGWFHPPANEIYRKNNISVFE 580


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
           [Homo sapiens]
          Length = 2073

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 15/82 (18%)

Query: 164 VEFTEEEIKTWGTV-----FQELNKLYPTHACREYLKNLPLL---SKYCGYREDNIPQLE 215
           +EF + EI+TW +      +  L KLY    C +Y+K+  +L   SK CG+         
Sbjct: 723 IEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGW-------FH 775

Query: 216 DVSNFLKERTGFSIRPVAGYLS 237
             +N +  R   S+  V G +S
Sbjct: 776 PPANEIYRRKDLSVFEVDGNMS 797


>gi|209413766 zinc finger and BTB domain containing 43 [Homo
           sapiens]
          Length = 467

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 5/62 (8%)

Query: 327 LRVFGAGLLSSISELKHALSGHAK----VKPFDPKITCKQECLITTF-QDVYFVSESFED 381
           LR +G G+     ++KH L GH K    +KP++  I  K+     +F + V   ++S+E 
Sbjct: 397 LRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEA 456

Query: 382 AK 383
           AK
Sbjct: 457 AK 458


>gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]
          Length = 467

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 5/62 (8%)

Query: 327 LRVFGAGLLSSISELKHALSGHAK----VKPFDPKITCKQECLITTF-QDVYFVSESFED 381
           LR +G G+     ++KH L GH K    +KP++  I  K+     +F + V   ++S+E 
Sbjct: 397 LRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEA 456

Query: 382 AK 383
           AK
Sbjct: 457 AK 458


>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
           [Homo sapiens]
          Length = 423

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 16/69 (23%), Positives = 34/69 (49%), Gaps = 5/69 (7%)

Query: 180 ELNKLYPT-HACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSP 238
           +LN+ + + H C E   +      YCG   ++ P+++ V++FL+     +I  +  Y+S 
Sbjct: 254 DLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR----NINQIKAYISM 309

Query: 239 RDFLSGLAF 247
             +   + F
Sbjct: 310 HSYSQHIVF 318


>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
          Length = 360

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 16/69 (23%), Positives = 34/69 (49%), Gaps = 5/69 (7%)

Query: 180 ELNKLYPT-HACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSP 238
           +LN+ + + H C E   +      YCG   ++ P+++ V++FL+     +I  +  Y+S 
Sbjct: 217 DLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR----NINQIKAYISM 272

Query: 239 RDFLSGLAF 247
             +   + F
Sbjct: 273 HSYSQHIVF 281


>gi|239753110 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 530

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 27  EVGGLIKALKIFQEKHVNLLHIESRKSK--RRNSEFEIFVDCDINREQLNDIFHLLKSHT 84
           + GG   A    + K ++ +HI  RK    R+  E +  V CDIN       +H +  H 
Sbjct: 149 QAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYHRISRHI 208

Query: 85  NVLS 88
           NV +
Sbjct: 209 NVFT 212


>gi|239747673 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 714

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 27  EVGGLIKALKIFQEKHVNLLHIESRKSK--RRNSEFEIFVDCDINREQLNDIFHLLKSHT 84
           + GG   A    + K ++ +HI  RK    R+  E +  V CDIN       +H +  H 
Sbjct: 255 QAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYHRISRHI 314

Query: 85  NVLS 88
           NV +
Sbjct: 315 NVFT 318


>gi|239741542 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 510

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 27  EVGGLIKALKIFQEKHVNLLHIESRKSK--RRNSEFEIFVDCDINREQLNDIFHLLKSHT 84
           + GG   A    + K ++ +HI  RK    R+  E +  V CDIN       +H +  H 
Sbjct: 255 QAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYHRISRHI 314

Query: 85  NVLS 88
           NV +
Sbjct: 315 NVFT 318


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 44  NLLHIESRKSKR--RNSEFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPD 93
           N L  +S K++   R SE  + +D D+ RE ++ +  L + H  VLS N+ D
Sbjct: 231 NSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMND 282


>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 365 LITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKD----TKSITSA 420
           L T  Q +   +        ++R   +TIK  F V+++   R I  L+D    TK+I   
Sbjct: 50  LETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109

Query: 421 MNELQHDLDVVSDALAKVSR 440
           + +   +L+  +D L +  R
Sbjct: 110 LQKYIRELEQANDDLERAKR 129


>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 365 LITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKD----TKSITSA 420
           L T  Q +   +        ++R   +TIK  F V+++   R I  L+D    TK+I   
Sbjct: 50  LETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109

Query: 421 MNELQHDLDVVSDALAKVSR 440
           + +   +L+  +D L +  R
Sbjct: 110 LQKYIRELEQANDDLERAKR 129


>gi|239752250 PREDICTED: similar to acetylserotonin
           O-methyltransferase-like [Homo sapiens]
          Length = 320

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 8/83 (9%)

Query: 226 GFSIRPVAGYLSPR---DFLSGLAFRVFH-CTQYVRHSSDPFYTPEPDTCHELLGHVPLL 281
           G+ I+ + G L      DFL+ + F + H C Q V+     +Y P P+     + H P+ 
Sbjct: 175 GYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKL----YYPPRPEDLRRSVKHDPIP 230

Query: 282 AEPSFAQFSQEIGLASLGASEEA 304
           A  +F   S   G  S     +A
Sbjct: 231 AADTFEDLSDVEGGGSEPTQRDA 253


>gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo
           sapiens]
          Length = 421

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 7/89 (7%)

Query: 102 METVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPI 161
           M+ V +F K+   + HC  +   YG    A+    +D + +   K F  L ++     P 
Sbjct: 236 MDLVTYFGKRPPGVLHCTTKFCDYGKAPGAEEYAQQDVLKKSYSKAFT-LTISALFVTPK 294

Query: 162 ---PKVEFTEEEIKTWGTVFQELNKLYPT 187
               +VE +E++++ W +   +++KL PT
Sbjct: 295 TTGARVELSEQQLQLWPS---DVDKLSPT 320


>gi|21686971 UDP-N-acetyl-alpha-D-galactosamine:polypeptide
           N-acetylgalactosaminyltransferase-like 5 [Homo sapiens]
          Length = 443

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 40/175 (22%), Positives = 69/175 (39%), Gaps = 39/175 (22%)

Query: 2   IEDNKENKDHSLE--RGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSE 59
           ++D KE  D+ LE  RG+  +I + K E  GLI+A  I               +   + +
Sbjct: 178 VDDLKEKLDYHLETFRGKVKIIRNKKRE--GLIRARLI--------------GASHASGD 221

Query: 60  FEIFVD--CDINREQLNDIFHLLKSHTNVL---SVNLPDNFTLKEDGME----TVPWFPK 110
             +F+D  C++NR  L  + H +     ++    +++ D+ TL+         T  W   
Sbjct: 222 VLVFLDSHCEVNRVWLEPLLHAIAKDPKMVVCPLIDVIDDRTLEYKPSPLVRGTFDW--- 278

Query: 111 KISDLDHCANRVLMY------GSELDADHPGFKDNVYRKRRKYFADLAMNYKHGD 159
              +L    + V  Y      GS      P     ++  RR YF ++    K  D
Sbjct: 279 ---NLQFKWDNVFSYEMDGPEGSTKPIRSPAMSGGIFAIRRHYFNEIGQYDKDMD 330


>gi|29570788 CSRP2 binding protein isoform b [Homo sapiens]
          Length = 654

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 4/28 (14%)

Query: 258 HSSDPFYTPEPDT----CHELLGHVPLL 281
           H SDP +TPEPD     C+    H+P +
Sbjct: 496 HRSDPHWTPEPDAPLDYCYVRPNHIPTI 523


>gi|24308203 CSRP2 binding protein isoform a [Homo sapiens]
          Length = 782

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 4/28 (14%)

Query: 258 HSSDPFYTPEPDT----CHELLGHVPLL 281
           H SDP +TPEPD     C+    H+P +
Sbjct: 624 HRSDPHWTPEPDAPLDYCYVRPNHIPTI 651


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,699,498
Number of Sequences: 37866
Number of extensions: 754036
Number of successful extensions: 1596
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1582
Number of HSP's gapped (non-prelim): 32
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.