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Search of human proteins with 4758650
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758650 kinesin family member 5C [Homo sapiens]
(957 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758650 kinesin family member 5C [Homo sapiens] 1862 0.0
gi|45446749 kinesin family member 5A [Homo sapiens] 1418 0.0
gi|4758648 kinesin family member 5B [Homo sapiens] 1409 0.0
gi|46852174 kinesin family member 3A [Homo sapiens] 300 4e-81
gi|71061468 centromere protein E [Homo sapiens] 293 4e-79
gi|4758646 kinesin family member 3B [Homo sapiens] 286 6e-77
gi|150010604 kinesin family member 4B [Homo sapiens] 284 2e-76
gi|116686122 kinesin family member 4 [Homo sapiens] 284 3e-76
gi|30794488 kinesin family member 27 [Homo sapiens] 282 9e-76
gi|38569484 kinesin family member 21A [Homo sapiens] 281 3e-75
gi|9910266 kinesin family member 15 [Homo sapiens] 274 3e-73
gi|13699824 kinesin family member 11 [Homo sapiens] 270 5e-72
gi|83716024 kinesin family member 21B [Homo sapiens] 267 3e-71
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 261 3e-69
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 261 3e-69
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 259 1e-68
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 245 1e-64
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 245 1e-64
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 245 1e-64
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 245 1e-64
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 243 8e-64
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 243 8e-64
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 238 2e-62
gi|41352705 kinesin family member 3C [Homo sapiens] 238 2e-62
gi|203096856 kinesin family member 7 [Homo sapiens] 230 4e-60
gi|46852172 kinesin family member 13B [Homo sapiens] 228 2e-59
gi|40254834 kinesin family member 1C [Homo sapiens] 222 1e-57
gi|148612831 kinesin family member 18A [Homo sapiens] 221 2e-57
gi|156616271 kinesin family member 19 [Homo sapiens] 219 1e-56
gi|122937289 kinesin family member 18B [Homo sapiens] 218 2e-56
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 1862 bits (4823), Expect = 0.0
Identities = 957/957 (100%), Positives = 957/957 (100%)
Query: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQE 60
MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQE
Sbjct: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQE 60
Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120
QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI
Sbjct: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120
Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180
YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV
Sbjct: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180
Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVS 240
MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVS
Sbjct: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVS 240
Query: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTI 300
KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTI
Sbjct: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTI 300
Query: 301 VICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVI 360
VICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVI
Sbjct: 301 VICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVI 360
Query: 361 QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEE 420
QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEE
Sbjct: 361 QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEE 420
Query: 421 ISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAA 480
ISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAA
Sbjct: 421 ISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAA 480
Query: 481 KDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELS 540
KDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELS
Sbjct: 481 KDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELS 540
Query: 541 NHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKS 600
NHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKS
Sbjct: 541 NHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKS 600
Query: 601 LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEES 660
LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEES
Sbjct: 601 LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEES 660
Query: 661 QDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSR 720
QDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSR
Sbjct: 661 QDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSR 720
Query: 721 LRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA 780
LRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA
Sbjct: 721 LRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA 780
Query: 781 REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENN 840
REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENN
Sbjct: 781 REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENN 840
Query: 841 LEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQE 900
LEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQE
Sbjct: 841 LEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQE 900
Query: 901 VDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNSTHYQK 957
VDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNSTHYQK
Sbjct: 901 VDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNSTHYQK 957
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 1418 bits (3670), Expect = 0.0
Identities = 716/939 (76%), Positives = 826/939 (87%), Gaps = 7/939 (0%)
Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQEQVYNA 65
ECSIKV+CRFRPLN+AEILRGDKFIP F+GD++VVIG GKPYVFDRV PPNTTQEQVY+A
Sbjct: 7 ECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYHA 65
Query: 66 CAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDE 125
CA QIVKDVL GYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA DIF+HIYSMDE
Sbjct: 66 CAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDE 125
Query: 126 NLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVID 185
NLEFHIKVSYFEIYLDKIRDLLDV+KTNL+VHEDKNRVP+VKGCTERFVSSPEE++DVID
Sbjct: 126 NLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVID 185
Query: 186 EGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAE 245
EGK+NRHVAVTNMNEHSSRSHSIFLINIKQEN+ETE+KLSGKLYLVDLAGSEKVSKTGAE
Sbjct: 186 EGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAE 245
Query: 246 GAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCS 305
GAVLDEAKNINKSLSALGNVISALAEGTK++VPYRDSKMTRILQDSLGGNCRTT+ ICCS
Sbjct: 246 GAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCS 305
Query: 306 PSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEM 365
PS +N+AETKSTLMFGQRAKTIKNT SVNLELTAE+WKKKYEKEKEK K K I LE
Sbjct: 306 PSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEA 365
Query: 366 ELNRWRNGEAVPEDEQISAKDQK-NLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSL 424
EL+RWRNGE VPE E+++ ++ E C+ TP+ DN + +V I+ EE++KY+EEI L
Sbjct: 366 ELSRWRNGENVPETERLAGEEAALGAELCEETPVNDN-SSIVVRIAPEERQKYEEEIRRL 424
Query: 425 YRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEV 484
Y+QLDDKDDEINQQSQL EKLKQQMLDQ+ELL STR D EK+Q EL+ LQ EN+AAKDEV
Sbjct: 425 YKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEV 484
Query: 485 KEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQK 544
KEVLQALEELAVNYDQKSQEVE+K++ N+ L DEL+QK T+ + + EL +LQE+S HQ+
Sbjct: 485 KEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQR 544
Query: 545 KRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNR 604
KR E+LN L+KDL E I+G ++K +++G IEEEFT+ARLYISK+KSEVKS+V R
Sbjct: 545 KRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKR 604
Query: 605 SKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSL 664
+QLE+ Q++ +RKM + REL++CQLLISQHEAKI+SLT+YMQ++E K+R LEES DSL
Sbjct: 605 CRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSL 664
Query: 665 SEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDE 724
S+ELAKL+AQE +HEV+ +DKE + QDA+E+KKALE QMESHREAH +QL+RLRDE
Sbjct: 665 SDELAKLQAQETVHEVALKDKEPD----TQDADEVKKALELQMESHREAHHRQLARLRDE 720
Query: 725 IEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDL 784
I EKQK IDE++DLNQKLQLE EKL +DY KLK E+ E+ KL++L L ++ EQ+++DL
Sbjct: 721 INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL 780
Query: 785 KGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQL 844
KGLEETV+RELQTLHNLRKLFVQD+TTRVKKS E++ +D GG +QKQKISFLENNLEQL
Sbjct: 781 KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL 840
Query: 845 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRI 904
TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE ALKEAKE AM+D++RYQQEVDRI
Sbjct: 841 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRI 900
Query: 905 KEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIR 943
KEAVR K+ +R HSAQIAKP+RPGHYPASSPT + R
Sbjct: 901 KEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTR 939
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 1409 bits (3648), Expect = 0.0
Identities = 727/959 (75%), Positives = 829/959 (86%), Gaps = 16/959 (1%)
Query: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQE 60
MAD AEC+IKVMCRFRPLNE+E+ RGDK+I KF+G++TVVI KPY FDRV +T+QE
Sbjct: 1 MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIAS-KPYAFDRVFQSSTSQE 59
Query: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120
QVYN CAK+IVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP+ MGIIPRI DIF++I
Sbjct: 60 QVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYI 119
Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180
YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNL+VHEDKNRVPYVKGCTERFV SP+EV
Sbjct: 120 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEV 179
Query: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVS 240
MD IDEGK+NRHVAVTNMNEHSSRSHSIFLIN+KQEN +TE+KLSGKLYLVDLAGSEKVS
Sbjct: 180 MDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVS 239
Query: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTI 300
KTGAEGAVLDEAKNINKSLSALGNVISALAEG+ T+VPYRDSKMTRILQDSLGGNCRTTI
Sbjct: 240 KTGAEGAVLDEAKNINKSLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTI 298
Query: 301 VICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVI 360
VICCSPS +NE+ETKSTL+FGQRAKTIKNTV VN+ELTAE+WKKKYEKEKEKNK L+N I
Sbjct: 299 VICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTI 358
Query: 361 QHLEMELNRWRNGEAVPEDEQISAKDQKNLE--PCDNTPIIDNIAP-----VVAGISTEE 413
Q LE ELNRWRNGE VP DEQ K++ NLE D + N P V+ + E
Sbjct: 359 QWLENELNRWRNGETVPIDEQFD-KEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAE 417
Query: 414 KEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRL 473
+ K +EEI+ LY+QLDDKD+EINQQSQL EKLK QMLDQ+ELLASTRRD + +Q EL RL
Sbjct: 418 RRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRL 477
Query: 474 QIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQREL 533
Q EN+A+K+EVKEVLQALEELAVNYDQKSQEVEDKT+ E L+DEL QK+ TL + EL
Sbjct: 478 QAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAEL 537
Query: 534 SQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISK 593
+L+E++NHQKKRA E++ LLKDL EIG +G NDVK + G+I+EEFT+ARLYISK
Sbjct: 538 QKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQ-PEGTGMIDEEFTVARLYISK 596
Query: 594 MKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQK 653
MKSEVK++V R KQLES Q +SN+KM +E+ELAACQL ISQHEAKIKSLT+Y+QN+EQK
Sbjct: 597 MKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQK 656
Query: 654 RRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREA 713
+RQLEES D+LSEEL +LRAQEK+HE+ EKEHL ++Q A E+K+A+EQQ++SHRE
Sbjct: 657 KRQLEESVDALSEELVQLRAQEKVHEM-----EKEHLNKVQTANEVKQAVEQQIQSHRET 711
Query: 714 HQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLL 773
HQKQ+S LRDE+E K K+I +++D NQK+ LEQE+L ++ KLK DQE+ KL +L ++
Sbjct: 712 HQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVM 771
Query: 774 NDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQK 833
D+REQAR+DLKGLEETV++ELQTLHNLRKLFVQDL TRVKKS E+D+DD GGSAAQKQK
Sbjct: 772 QDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQK 831
Query: 834 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 893
ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENA RD
Sbjct: 832 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRD 891
Query: 894 RKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNS 952
RKRYQQEVDRIKEAVR+KNMARR HSAQIAKPIRPG +PA+SPT AIRGGG NS
Sbjct: 892 RKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNS 950
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 300 bits (768), Expect = 4e-81
Identities = 205/574 (35%), Positives = 309/574 (53%), Gaps = 32/574 (5%)
Query: 4 PAEC-SIKVMCRFRPLNEAE---ILRGDKFIPKFKGDETVVIGQG-----KPYVFDRVLP 54
P C ++KV+ R RPLNE E + + + +G TV K + FD V
Sbjct: 9 PESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFG 68
Query: 55 PNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAH 114
P + Q VYN A+ I+ VLEGYNGTIFAYGQT +GKT TMEG P+L GIIP
Sbjct: 69 PESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFA 128
Query: 115 DIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN-LAVHEDKNRVPYVKGCTERF 173
IF HI + + F ++VSY EIY +++RDLL +T L V E + Y+K +
Sbjct: 129 HIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYV 188
Query: 174 VSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS---GKLYL 230
V++ +++ ++ G NR V TNMNEHSSRSH+IF I I+ + + GKL+L
Sbjct: 189 VNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHL 248
Query: 231 VDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQD 290
VDLAGSE+ +KTGA G L EA IN SLS LGNVISAL +G THVPYR+SK+TR+LQD
Sbjct: 249 VDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQD 308
Query: 291 SLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEK 350
SLGGN +T + P+ +N ET STL + RAK IKN +N E + ++++KE
Sbjct: 309 SLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN-EDPKDALLRQFQKEI 367
Query: 351 EKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGIS 410
E+ K ++E +G + E+ ++ + E + V
Sbjct: 368 EELKK--------KLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKM 419
Query: 411 TEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEEL 470
E + K DEE +L +LD +++E N+ EK ++ +L +++++ + E+L
Sbjct: 420 IEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLL-------KAQQEHQSLLEKL 472
Query: 471 TRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQ 530
+ L E + V ++L EE ++ + E+E++ + EQL EL +K +
Sbjct: 473 SAL--EKKVIVGGV-DLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIE 529
Query: 531 RELSQLQELSNHQKKRATEILNLLLKDLGEIGGI 564
+ + LQE + + K+ ++ +L+ E+ +
Sbjct: 530 EKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADL 563
Score = 41.2 bits (95), Expect = 0.005
Identities = 79/368 (21%), Positives = 153/368 (41%), Gaps = 54/368 (14%)
Query: 499 DQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQE-LSNHQKKRATEILNLLLKD 557
D E + KT A Q E + +L+T +S L + S H R +++ LL
Sbjct: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDS 309
Query: 558 LGEIGGIIGTNDVKTLADVNGV-IEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSN 616
LG G + A++ + T++ L + + K++ N+++ E +
Sbjct: 310 LG------GNSKTMMCANIGPADYNYDETISTL---RYANRAKNIKNKARINEDPKDALL 360
Query: 617 RKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEK 676
R+ EL E + S +D + E + E +D E+ K R ++K
Sbjct: 361 RQFQKEIEELKK-----KLEEGEEISGSDISGSEEDDDEEGEVGEDG--EKRKKRRGKKK 413
Query: 677 MHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDE-------IEEKQ 729
+ DK E ++ +E +KALE +++ E K + L +E Q
Sbjct: 414 VSP----DKMIEMQAKI---DEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQ 466
Query: 730 KIIDEIRDLNQKLQL----------EQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQ 779
+++++ L +K+ + EQEKL + N +E +ER + E+L +++EQ
Sbjct: 467 SLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESN---MELEERRKRAEQLRRELEEKEQ 523
Query: 780 AREDLKGLEETVSRELQ-TLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLE 838
R D++ ++ E Q L+K++ L + +L + +++I L
Sbjct: 524 ERLDIEEKYTSLQEEAQGKTKKLKKVWTM-LMAAKSEMADLQQE-------HQREIEGLL 575
Query: 839 NNLEQLTK 846
N+ QL++
Sbjct: 576 ENIRQLSR 583
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 293 bits (751), Expect = 4e-79
Identities = 296/1048 (28%), Positives = 480/1048 (45%), Gaps = 167/1048 (15%)
Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVV--IGQGKPYVFDRVLPPNTTQEQVY 63
E ++ V R RPLN E G+ +K D V+ + K + FDRV N T + VY
Sbjct: 4 EGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVY 63
Query: 64 NACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSM 123
A I+ ++GYNGTIFAYGQT+SGKT+TM G +G+IPR HDIF I
Sbjct: 64 EEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMG---SEDHLGVIPRAIHDIFQKIKKF 120
Query: 124 DENLEFHIKVSYFEIYLDKIRDLL--DVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181
+ EF ++VSY EIY + I DLL L + ED NR YV TE V + E +
Sbjct: 121 PDR-EFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMAL 179
Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ------ENVETEKKLSGKLYLVDLAG 235
I +G+ +RH T MN+ SSRSH+IF + ++ N E K+S L LVDLAG
Sbjct: 180 KWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVS-HLNLVDLAG 238
Query: 236 SEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-TKTHVPYRDSKMTRILQDSLGG 294
SE+ ++TGA G L E NIN+SL LG VI L++G + YRDSK+TRILQ+SLGG
Sbjct: 239 SERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGG 298
Query: 295 NCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKE----- 349
N +T I+ +P F+ ET + L F AK +KNT VN T E K+Y KE
Sbjct: 299 NAKTRIICTITPVSFD--ETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLK 356
Query: 350 --------------KEKNKTL-----KNVIQHLEME----LNRWR-NGEAVPEDEQISAK 385
EK++ K+++Q ++ E L R ++ +++ AK
Sbjct: 357 KQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAK 416
Query: 386 DQKNLEPC-------------DNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKD 432
++ + C D I NI +S + DE + S + D
Sbjct: 417 RKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCS---ESDVFS 473
Query: 433 DEINQQSQLAEKLKQQMLDQDEL---LASTRRDYEKIQEELTRLQIENEAAKDEVKE--- 486
+ ++ S++ ++L+Q+ + L S R DY+ + + +L+ E E + ++KE
Sbjct: 474 NTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKND 533
Query: 487 --VLQALEELAVNYDQKSQEVEDKTRA----------NEQLTDELAQKTTTLTTTQRELS 534
+ALE DQ+ Q + + + N+ L +EL+ K L + ++
Sbjct: 534 LDEFEALER-KTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIK 592
Query: 535 QLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVK-TLADVNGV---IEEEFTMARLY 590
+LQE + QK + N+ + + I +K TL D V + E R
Sbjct: 593 KLQEYIDSQK-----LENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSE 647
Query: 591 ISKMKSEVKSLVNRSKQLES------AQMDSNRKMNAS-ERELAACQLLISQHEAKI--K 641
++K ++K L KQ+E+ +Q+++ +KM E+EL + I++ + I K
Sbjct: 648 NLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGK 707
Query: 642 SLTDYMQNME----------QKRRQLEESQ------------DSLSEELAKLR--AQEKM 677
D + N+E + +++EE++ SL E+ +LR Q+K
Sbjct: 708 VPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKS 767
Query: 678 HEVSFQDKEKEHL--------TRLQ--------------DAEEMKKALEQQMESHREAHQ 715
E+ EK+ L +R+Q + K+ +Q+ ++ + H
Sbjct: 768 EELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHM 827
Query: 716 KQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLND 775
+ + +EE +++ EI +L+++ Q L + +L + QE + K ++ +
Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN 887
Query: 776 KREQAREDLKGLEETVSRELQTLHNLRKLFVQDL--TTRVKKSVELDNDDGGGSAAQKQK 833
+ EQ +E L+ + T LQT+ + L + L T K++ + DD KQ
Sbjct: 888 EMEQLKEQLENRDST----LQTVEREKTLITEKLQQTLEEVKTLTQEKDD------LKQL 937
Query: 834 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKE-------A 886
L+ +QL V N D + +L + L+ E + L+S + E
Sbjct: 938 QESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHM 997
Query: 887 KENAMRDRKRYQQEVDRI--KEAVRAKN 912
+EN + +QQ++ I K+ + AKN
Sbjct: 998 EENTGETKDEFQQKMVGIDKKQDLEAKN 1025
Score = 97.4 bits (241), Expect = 6e-20
Identities = 125/556 (22%), Positives = 239/556 (42%), Gaps = 83/556 (14%)
Query: 411 TEEKEKYDEEISSLY-------RQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDY 463
++E +K+D + +L ++L +K E+ ++ E+LK+Q+ ++D L + R+
Sbjct: 851 SKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREK 910
Query: 464 EKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKT 523
I E+L + E + E ++ Q E L + DQ ++ D N
Sbjct: 911 TLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMN----------- 959
Query: 524 TTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEE 583
+ T ++ + L+ L HQ E +N L + E + + + G ++E
Sbjct: 960 --IDTQEQLRNALESLKQHQ-----ETINTLKSKISE-----EVSRNLHMEENTGETKDE 1007
Query: 584 FTMARLYISKMKS-EVKSLVNRSKQLESAQ-MDSNRKMNASERELAACQLLISQHEAKIK 641
F + I K + E K+ + ++ + ++ RK+ + +E Q ++ A+ +
Sbjct: 1008 FQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKE 1067
Query: 642 SL-TDYMQNMEQKRRQLEESQDSLSEELAK---LRAQEKMHEVSFQDKEKEHLTRLQDAE 697
L TD +N+E EE + L +EL K + AQEK H + + + RL + E
Sbjct: 1068 QLKTDLKENIEMTIENQEELR-LLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVE 1126
Query: 698 EMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDL-----NQKLQLEQ------ 746
E K QQ++ Q+QL +++E+ E QK I+EI +L N++L LE
Sbjct: 1127 EKLKEKSQQLQE----KQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERL 1182
Query: 747 ---EKLSSDYNKLKIEDQEREMKLEKLLLLNDKRE--------------QAREDLKGLEE 789
+KL+ +Y ++K +ER++ E +R+ Q +E+LK
Sbjct: 1183 ELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHI 1242
Query: 790 TVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHK 849
+ +T+ LR+ V + T ++ + +L+ +++I L E L V +
Sbjct: 1243 HLKEHQETIDELRR-SVSEKTAQIINTQDLEK----SHTKLQEEIPVLHEEQELLPNVKE 1297
Query: 850 QLVRDNADLRCELPKLEKRL----RATAERVKALESALKEAKENAMRDRKRYQQEVDR-- 903
V + + EL L ++ T R++ L E + + + K +E D
Sbjct: 1298 --VSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLK 1355
Query: 904 -IKEAVRAKNMARRAH 918
IKEA+ K+ + H
Sbjct: 1356 TIKEALEVKHDQLKEH 1371
Score = 94.0 bits (232), Expect = 6e-19
Identities = 133/646 (20%), Positives = 292/646 (45%), Gaps = 79/646 (12%)
Query: 326 TIKNTVSVNLELTAEEWKKKYEKEK---EKNKTLKNVIQHLEMELNRWRNGEAVPEDEQI 382
T+++ + LEL A++ + YE+ K ++ K LK + + E E + R E +
Sbjct: 1173 TLEHMETERLEL-AQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGL 1231
Query: 383 SAKDQKNLEPC---DNTPIIDNIAPVVAG-----ISTEEKEKYDEEISSLYRQLDDKDDE 434
K++ + ++ ID + V+ I+T++ EK ++ L ++ +
Sbjct: 1232 QTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQEL 1291
Query: 435 INQQSQLAEKLKQQMLDQDELLA--STRRD---YEKIQEELTRLQIENEAAKDEVKEV-- 487
+ +++E Q+ +++ ELL ST +D +I+ E RL + + +++E+K +
Sbjct: 1292 LPNVKEVSET--QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTK 1349
Query: 488 ----LQALEE-LAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNH 542
L+ ++E L V +DQ + + + T A Q + +++ + E +++
Sbjct: 1350 ERDNLKTIKEALEVKHDQLKEHIRE-TLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQ 1408
Query: 543 QKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLV 602
K + + +L + ++ LG + ++D ++ V +E+ + RL ++SE L
Sbjct: 1409 FKPKDSALLRIEIEMLGLSKRLQESHD-----EMKSVAKEKDDLQRLQ-EVLQSESDQLK 1462
Query: 603 NRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQK----RRQLE 658
K++ + +++ E EL + + E I L + E + ++QLE
Sbjct: 1463 ENIKEIVAKHLET-------EEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLE 1515
Query: 659 ESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQL 718
D L ++ ++ +E+ + + +E + L+ +E +KA + ++S +
Sbjct: 1516 AINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELT 1575
Query: 719 SRLRDEIEEKQKII---DEIRDLNQKLQLEQEKLSSDYNKLKI---EDQEREMKLEKLLL 772
+RL++ EE Q +I +E++ + + LQ+E+++L + ++ E QE+E + K+
Sbjct: 1576 NRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTA 1635
Query: 773 LNDKREQ--AREDLKGLEETVSRELQTL--HNLRKLFVQDLTTRVKKSVELDNDDGGGSA 828
+N+ +E+ E LK ET L+ + N+R + +SV + DD
Sbjct: 1636 VNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDD----- 1690
Query: 829 AQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK-LEKRLRATAERVKALESALKEAK 887
++E+ KV + +++N LR + + LEK+ E +K + LKE +
Sbjct: 1691 ---------LRSVEETLKVERDQLKEN--LRETITRDLEKQ-----EELKIVHMHLKEHQ 1734
Query: 888 ENAMRDR---KRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGH 930
E + R E+ +++ + N A +A +I + +R H
Sbjct: 1735 ETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAH 1780
Score = 92.4 bits (228), Expect = 2e-18
Identities = 139/698 (19%), Positives = 301/698 (43%), Gaps = 128/698 (18%)
Query: 306 PSVFNEAETKSTL----MFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTL----- 356
P+V +ET+ T+ + +++ T +T +E+ +K+++ +E+ K+L
Sbjct: 1293 PNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERD 1352
Query: 357 --KNVIQHLEMELNRWRNG--EAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTE 412
K + + LE++ ++ + E + + ++ +K +++L + +
Sbjct: 1353 NLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSL-------------------NMK 1393
Query: 413 EKEKYDEEISSLYRQLDDKDD---EINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEE 469
EK+ +I S Q KD I + K Q+ D+ + +A + D +++QE
Sbjct: 1394 EKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEV 1453
Query: 470 LTRLQIENEAAKDEVKEVL---------------------QALEELAVNYDQKSQEVEDK 508
L Q E++ K+ +KE++ + + EL VN +K E+
Sbjct: 1454 L---QSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI 1510
Query: 509 TRANEQLTDELAQKTTTL------------TTTQRELSQLQELSNHQKKRATEILNLLLK 556
+ E + D+L K + + Q ++++L++ H+K + + + ++ K
Sbjct: 1511 QKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESK 1570
Query: 557 DLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYIS------KMKSEVKSLVNRSKQLES 610
L + + + ++ +I+E+ M R+ + ++K K +V + K+ +
Sbjct: 1571 MLELTNRLQESQE-----EIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQE 1625
Query: 611 AQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLE-------ESQDS 663
+ + +E + C++ + + + + L ++N+E + +L E S
Sbjct: 1626 KEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLN--LENIETENIRLTQILHENLEEMRS 1683
Query: 664 LSEELAKLRAQE---KMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQ--- 717
+++E LR+ E K+ ++ +E +TR + +E K + ++ H+E K
Sbjct: 1684 VTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGI 1743
Query: 718 LSRLRDEIEEKQKIIDEIRDLNQKLQLE-QEKLSSDYNKLKIEDQEREMKLEKLLL-LND 775
+S +EI QK ++ D + L+ QE+L + LK E QE KL ++ D
Sbjct: 1744 VSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLK-EQQETIDKLRGIVSEKTD 1802
Query: 776 KREQAREDLKGLEETVSRELQTL----HNLRKLFVQDLTTRVKKSVELDN---------- 821
K ++DL+ + ++Q L H L L +D+ KK E++
Sbjct: 1803 KLSNMQKDLENSNAKLQEKIQELKANEHQLITL-KKDVNETQKKVSEMEQLKKQIKDQSL 1861
Query: 822 -----DDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEK-RLRATAER 875
+ + AQK L NLE++ V K+ RDN E KLE+ +L+ + +
Sbjct: 1862 TLSKLEIENLNLAQK-----LHENLEEMKSVMKE--RDNLRRVEETLKLERDQLKESLQE 1914
Query: 876 VKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNM 913
KA + +++ + A K +++ VD+++E + K +
Sbjct: 1915 TKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTI 1952
Score = 90.9 bits (224), Expect = 5e-18
Identities = 142/767 (18%), Positives = 329/767 (42%), Gaps = 73/767 (9%)
Query: 210 LINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVI--- 266
L+N+++E E +KK++ L + +++++ E L+ A+ +N++ + ++
Sbjct: 1143 LLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKER 1202
Query: 267 SALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKT 326
L E K+ RD I + G + + ET L KT
Sbjct: 1203 KVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKT 1262
Query: 327 IKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKD 386
+ + +LE + + +++ E+ + L NV E+ + E EQ + KD
Sbjct: 1263 AQIINTQDLEKSHTKLQEEIPVLHEEQELLPNV---KEVSETQETMNELELLTEQSTTKD 1319
Query: 387 QKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDD----------KDDEIN 436
L + + N E+ ++ EEI SL ++ D+ K D++
Sbjct: 1320 STTLARIEMERLRLN----------EKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLK 1369
Query: 437 QQ-SQLAEKLKQQMLDQDELLASTRRDYE--KIQEELTRLQIENEAAKDEVKEVLQALEE 493
+ + K+++ Q++ L +D E KI E+ + + ++ A E+L +
Sbjct: 1370 EHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR 1429
Query: 494 LAVNYDQK---SQEVEDKTRANEQL---TDELAQKTTTLTTTQRELSQLQELSNHQKKRA 547
L ++D+ ++E +D R E L +D+L + + E + ++++ K
Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ 1489
Query: 548 TEILNLLLKDLGEIGGIIGT--NDVKTLAD-VNGVIEEEFTMARLYISKMKSEVKSLVNR 604
E +N L +L E I T ++ + D + I+E + + K SEV+ VN
Sbjct: 1490 EETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNE 1549
Query: 605 SKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSL 664
KQ + + + + + E ++ + + + +I+ + + M++ + L+ +D L
Sbjct: 1550 LKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQL 1609
Query: 665 SEE----LAKLR-AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQ---MESHREAHQK 716
E +AK++ +QEK ++ E ++ + E +K+ E Q +E+ + +
Sbjct: 1610 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIR 1669
Query: 717 QLSRLRDEIEEKQKII---DEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLL 773
L + +EE + + D++R + + L++E+++L + + D E++ +L+ + +
Sbjct: 1670 LTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH 1729
Query: 774 NDKREQAREDLKGLEETVSRELQTL-----HNLRKLFVQDLTTR---------VKKSVEL 819
+ ++ + L+G+ + E+ + H+ L QDL + +K+ E
Sbjct: 1730 LKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQET 1789
Query: 820 DNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 879
+ G + + K+S ++ +LE ++ +++ +L L+K + T ++V +
Sbjct: 1790 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEM 1849
Query: 880 ESALKEAKENAMRDRK----------RYQQEVDRIKEAVRAKNMARR 916
E K+ K+ ++ K + + ++ +K ++ ++ RR
Sbjct: 1850 EQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRR 1896
Score = 79.0 bits (193), Expect = 2e-14
Identities = 109/513 (21%), Positives = 231/513 (45%), Gaps = 57/513 (11%)
Query: 415 EKYDEEISSLYRQLDDKDDEI-NQQSQLA---EKLKQQMLDQDELLASTRRDYEKIQEEL 470
+++ E I L + +K +EI N Q L + LK Q L E L ++ QE +
Sbjct: 1731 KEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETI 1790
Query: 471 TRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQ 530
+L+ D++ + + LE N + K QE + +ANE +L + TQ
Sbjct: 1791 DKLRGIVSEKTDKLSNMQKDLE----NSNAKLQEKIQELKANEH---QLITLKKDVNETQ 1843
Query: 531 RELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLY 590
+++S++++L K ++ + L +++L + + L ++ V++E + R+
Sbjct: 1844 KKVSEMEQLKKQIKDQSLTLSKLEIENLN-----LAQKLHENLEEMKSVMKERDNLRRV- 1897
Query: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQN- 649
E + R + ES Q R + ++EL ++L +H+ + L + +
Sbjct: 1898 ------EETLKLERDQLKESLQETKARDLEI-QQELKTARMLSKEHKETVDKLREKISEK 1950
Query: 650 ---MEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQ 706
+ ++ L++S+D L +++ +L+ +E +D H ++ + E++KK E Q
Sbjct: 1951 TIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSH-KKINEMEQLKKQFEAQ 2009
Query: 707 ---MESHREAHQKQLSRLRDEIEEKQKII---DEIRDLNQKLQLEQEKLSSDYNKLKIED 760
M+S R + + +L + +EE + + DE+R + + L++E+++ + ++ D
Sbjct: 2010 NLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARD 2069
Query: 761 -QEREMKLEKLLLLNDKR---EQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKS 816
Q ++K EK LL + ++ E RE ++E + R + + L L+ ++K
Sbjct: 2070 RQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECL--NRLSLDLEKE 2127
Query: 817 VELDNDDGGGSAAQKQKISFLENNLE---QLTKVHKQLVRDNADLRCELPKLEKRLRATA 873
+E QK+ ++ NL TK ++L N E ++ K+L+
Sbjct: 2128 IEF----------QKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVL 2177
Query: 874 ERVKALESALKEAKENAMRDRKRYQQEVDRIKE 906
V ++ +E E+ + + EV++ KE
Sbjct: 2178 SYVTKIK---EEQHESINKFEMDFIDEVEKQKE 2207
Score = 54.7 bits (130), Expect = 4e-07
Identities = 170/890 (19%), Positives = 366/890 (41%), Gaps = 144/890 (16%)
Query: 118 DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSP 177
D + + D ++ +++++ ++L + ++ +D + ++ DK + + +S
Sbjct: 1763 DALKAQDLKIQEELRIAH--MHLKEQQETIDKLRGIVSEKTDK-----LSNMQKDLENSN 1815
Query: 178 EEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSE 237
++ + I E KAN H LI +K++ ET+KK+S L +
Sbjct: 1816 AKLQEKIQELKANEHQ----------------LITLKKDVNETQKKVSEMEQLKKQIKDQ 1859
Query: 238 KVSKTGAEGAVLDEAKNINKSLSALGNVISA---LAEGTKTHVPYRDSKMTRILQDSLGG 294
++ + E L+ A+ ++++L + +V+ L +T RD ++ LQ++
Sbjct: 1860 SLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERD-QLKESLQETKAR 1918
Query: 295 NCRTTIVICCSPSVFNE-AETKSTLMFGQRAKTIK-NTVSVNLELTAEEWKKKYEKEKEK 352
+ + + + E ET L KTI+ + + +L+ + +E +KK ++ ++K
Sbjct: 1919 DLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKK 1978
Query: 353 NKTLKNVIQHLEM---ELNRWRNGEAVPEDEQISAKD---------QKNLEPCDNTPIID 400
L V + + M ++N + E + +S + +K E + I+
Sbjct: 1979 ELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVA 2038
Query: 401 NIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQ-----------QSQLAEKLKQQM 449
+ I K + D+ I++L R++ +D + +Q Q L E L+++
Sbjct: 2039 KERDELRRIKESLKMERDQFIATL-REMIARDRQNHQVKPEKRLLSDGQQHLTESLREKC 2097
Query: 450 LDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEV-LQALEELAVNYDQKSQEVEDK 508
ELL + + E L RL ++ E + KE+ ++ L++ Y Q ++ +E
Sbjct: 2098 SRIKELL-KRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQ-TKHIEKL 2155
Query: 509 TRANEQLTDELAQKTTTLTTTQRELSQLQELSNH---------------QKKRATEILNL 553
AN++ + E + L +++++E + QK+ +I +L
Sbjct: 2156 FTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHL 2215
Query: 554 L---------LKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNR 604
L+DL ++ + + + L D + E EF + ++ S K +
Sbjct: 2216 QQDCDVPSRELRDL-KLNQNMDLHIEEILKDFS---ESEFPSIKTEFQQVLSNRKEMTQF 2271
Query: 605 SKQLESAQMDSNRKMNASEREL-AACQL---LISQHEAKIKSLTDYMQNMEQKRRQLEES 660
++ + + D + N ++E CQ+ ++ A + T++ + ++ E+
Sbjct: 2272 LEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQD 2331
Query: 661 QDSLSEELAKLRAQEKMHEVSF----------QDKEKEHLT------RLQDAEEMKKALE 704
SL E+ KL + + S QD + H+T + E++ +L
Sbjct: 2332 LKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLH 2391
Query: 705 QQMES--HREAH----QKQLSRLRDEIEEKQKIIDE----IRDLNQKLQLEQEKLSSDYN 754
+ ES H+E+ QK+L D I + Q + E + + +Q+ Q+K++
Sbjct: 2392 EAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAK 2451
Query: 755 KLKIEDQEREMKLEKLLLLNDKREQARE---DLKGLEETVSRELQTLHNLRKLFVQDLTT 811
K E ++ +MKL K+ L +K + A+E ++ + TV + + + LR+ +
Sbjct: 2452 PYKEEIEDLKMKLVKIDL--EKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQA 2509
Query: 812 RVKKSVELDNDD---------GGGSA---------------AQKQKISFLENNLEQLTKV 847
+ + D GGGS +++IS L+ EQL K
Sbjct: 2510 QDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQ 2569
Query: 848 HKQLVRDNADLRCELPKLEKR-LRATAERVKALESALKEAKENAMRDRKR 896
+L+ +N L E+ ++R L+ A + E++ K K +K+
Sbjct: 2570 KNELLSNNQHLSNEVKTWKERTLKREAHKQVTCENSPKSPKVTGTASKKK 2619
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 286 bits (732), Expect = 6e-77
Identities = 224/721 (31%), Positives = 351/721 (48%), Gaps = 128/721 (17%)
Query: 8 SIKVMCRFRPLNEAEILRG-DKFIPKFKGDETVVIGQ-------------GKPYVFDRVL 53
S++V+ R RP+N E DK + D V +GQ K + FD V
Sbjct: 9 SVRVVVRCRPMNGKEKAASYDKVV-----DVDVKLGQVSVKNPKGTAHEMPKTFTFDAVY 63
Query: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
N Q ++Y+ + +V VL+G+NGTIFAYGQT +GKT+TMEG DP+ G+IP
Sbjct: 64 DWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSF 123
Query: 114 HDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN-LAVHEDKNRVPYVKGCTER 172
IF HI S +N ++ ++ SY EIY ++IRDLL +T L + E + YVK +
Sbjct: 124 DHIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSF 182
Query: 173 FVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS---GKLY 229
S +E+ V++ G NR V TNMNEHSSRSH+IF+I I+ V + + GKL
Sbjct: 183 VTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLN 242
Query: 230 LVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQ 289
LVDLAGSE+ +KTGA+G L EA IN SLSALGNVISAL +G TH+PYRDSK+TR+LQ
Sbjct: 243 LVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQ 302
Query: 290 DSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKE 349
DSLGGN +T +V P+ +N ET +TL + RAK IKN VN E + +++++E
Sbjct: 303 DSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVN-EDPKDALLREFQEE 361
Query: 350 KEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGI 409
I L+ +L + G +++ +G
Sbjct: 362 ----------IARLKAQLEKRSIGRRKRREKRREGGG--------------------SGG 391
Query: 410 STEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTR----RDYEK 465
EE+E+ EE + DDKDD +Q + E K+ +++ L+A + ++ EK
Sbjct: 392 GGEEEEEEGEEGE---EEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEK 448
Query: 466 IQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTT 525
E+L R E +AA+ ++ +L V + + D T +++ ++ Q+
Sbjct: 449 KMEDLRR---EKDAAEMLGAKIKAMESKLLVG----GKNIVDHTNEQQKILEQKRQEIAE 501
Query: 526 LTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFT 585
+RE+ Q E + + E + L +++ D+KT
Sbjct: 502 QKRREREIQQQMESRDEETLELKETYSSLQQEV----------DIKTKK----------- 540
Query: 586 MARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTD 645
+ K+ S+++++ L+ + +++ ++ EL E K+K L
Sbjct: 541 -----LKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT--------RELKLKHL-- 585
Query: 646 YMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEH-----LTRLQDAEEMK 700
+ E L + K+ +F D+E++H +TRL++ + MK
Sbjct: 586 ------------------IIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMK 627
Query: 701 K 701
+
Sbjct: 628 R 628
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/274 (19%), Positives = 122/274 (44%), Gaps = 34/274 (12%)
Query: 648 QNMEQKRRQLEESQDSL----SEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKAL 703
+N++ K R E+ +D+L EE+A+L+AQ + + + + ++ ++
Sbjct: 338 KNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEE 397
Query: 704 EQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIED--- 760
E+ E E K D R+ +KL++E+ + D++ + E
Sbjct: 398 EEGEEGEEEGDDKD---------------DYWREQQEKLEIEKRAIVEDHSLVAEEKMRL 442
Query: 761 -QEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVEL 819
+E+E K+E L D E +K +E S+ L N + D T +K +E
Sbjct: 443 LKEKEKKMEDLRREKDAAEMLGAKIKAME---SKLLVGGKN-----IVDHTNEQQKILEQ 494
Query: 820 DNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 879
+ A QK++ ++ +E + +L + L+ E+ K+L+ +++A+
Sbjct: 495 KRQE---IAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAV 551
Query: 880 ESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNM 913
++ + + +E +++R+ +Q + + ++ K++
Sbjct: 552 KAEIHDLQEEHIKERQELEQTQNELTRELKLKHL 585
Score = 38.5 bits (88), Expect = 0.030
Identities = 65/325 (20%), Positives = 136/325 (41%), Gaps = 39/325 (12%)
Query: 480 AKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL 539
A V+E L L Y +++ +++K R NE D L ++ R +QL++
Sbjct: 320 ASYNVEETLTTLR-----YANRAKNIKNKPRVNEDPKDALLREFQE--EIARLKAQLEKR 372
Query: 540 SNHQKKRATEILN--------LLLKDLGEIGGIIGTN--------DVKTLADVNGVIEEE 583
S ++KR + ++ GE G G + K + ++E+
Sbjct: 373 SIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDH 432
Query: 584 FTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSL 643
+A + +K + K + + ++ ++A+M + + L + ++ + K L
Sbjct: 433 SLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKIL 492
Query: 644 TDYMQNMEQKRRQLEESQ---DSLSEELAKLRA--QEKMHEVSFQDKE-KEHLTRLQDAE 697
Q + +++R+ E Q +S EE +L+ EV + K+ K+ ++LQ +
Sbjct: 493 EQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVK 552
Query: 698 -EMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKL 756
E+ E+ ++ +E Q Q + L E++ K II+ L +K S N+
Sbjct: 553 AEIHDLQEEHIKERQELEQTQ-NELTRELKLKHLIIENFIPLEEK--------SKIMNRA 603
Query: 757 KIEDQEREMKLEKLLLLNDKREQAR 781
+++E KL + L +++ R
Sbjct: 604 FFDEEEDHWKLHPITRLENQQMMKR 628
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 284 bits (727), Expect = 2e-76
Identities = 268/947 (28%), Positives = 454/947 (47%), Gaps = 70/947 (7%)
Query: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGDET-VVIGQGKPYVFDRVLPPNTTQEQVYNACA 67
++V R RPL EI G + F ET VV+G K + +D V P T QE+V+N
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
Query: 68 KQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAHDIFDHIYSM 123
++K + +GYN T+ AYGQT SGKT++M G Q +GIIPR+ +F I
Sbjct: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEI-DK 128
Query: 124 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181
+ EF +KVSY EIY ++I DLL S K + + ED + G TE+ V + +
Sbjct: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS--GKLYLVDLAGSEKV 239
+++G +R VA T MN SSRSH+IF I+I+Q +++K S KL+LVDLAGSE+
Sbjct: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK-KSDKNCSFRSKLHLVDLAGSERQ 247
Query: 240 SKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-THVPYRDSKMTRILQDSLGGNCRT 298
KT AEG L E NIN+ L LGNVISAL + K + VPYRDSK+TR+LQDSLGGN T
Sbjct: 248 KKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHT 307
Query: 299 TIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLE-LTAEEWKKKYEKEKEKNKTLK 357
++ C SP+ N ET STL + RA+ IKN VN++ TAE K + ++ + L+
Sbjct: 308 LMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQ 367
Query: 358 NVIQHLEMELNR--WRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEE-K 414
L +N N +++ E Q ++ + L C + + I TE+
Sbjct: 368 AHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVN 427
Query: 415 EKYDEEISSLYRQLDDKDD-----EINQQSQLAEKLK-----QQMLDQ--DELLASTRRD 462
EK + ++ L + + K D E + +L E ++ QQ++ Q DE +A T
Sbjct: 428 EKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACTAAA 487
Query: 463 YEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQK 522
+ EE +++ E ++ Q A++ Q S+EV + A L + L +K
Sbjct: 488 IDTAVEEEAQVETSPETSRSSDAFTTQH----ALHQAQMSKEVVELNNA-LALKEALVRK 542
Query: 523 TTTLTTTQRELSQLQ-ELSNHQKKRATEILNLLLKDLGEIGGIIGT-----NDVKTLADV 576
+T +L +Q + ++ K E++N L K+ E+ + T N K
Sbjct: 543 ---MTQNDNQLQPIQFQYQDNIKNLELEVIN-LQKEKEELVRELQTAKKNVNQAKLSEHR 598
Query: 577 NGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQ----LL 632
+ +++E + +++K +N +L + + R ++ +E+ + L
Sbjct: 599 HKLLQE--------LEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQL 650
Query: 633 ISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLT- 691
+ Q + + + Q +++ QL+E EL KL + + K +E
Sbjct: 651 MRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAA 710
Query: 692 --RLQDA-EEMKKALEQQMESHREAHQKQLSRLR----DEIEEKQKIIDEIRDLNQKLQL 744
RL+DA ++ ++ +++ E+ + +R+R +EIE + R LN L+
Sbjct: 711 NKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLE- 769
Query: 745 EQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKL 804
+++ L+ D +LK + + RE KL + + E+ +++++++L +L
Sbjct: 770 DRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMEL 829
Query: 805 FVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 864
+ +K ++ +++D KQ + LE + K L+ + + + K
Sbjct: 830 RSAQIADLQQKLLDAESED-----RPKQCWENIATILEAKCAL-KYLIGELVSSKIHVTK 883
Query: 865 LEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAK 911
LE LR + ++ L E + + Q E+ R+++ + K
Sbjct: 884 LENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEK 930
Score = 65.5 bits (158), Expect = 2e-10
Identities = 94/441 (21%), Positives = 193/441 (43%), Gaps = 33/441 (7%)
Query: 334 NLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPC 393
NLEL +K+ E+ + +T K + ++ +R + + + + QI+ +K E
Sbjct: 563 NLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQEL--EGQIADLKKKLNEQS 620
Query: 394 DNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQD 453
+ ++ V+ ++ E ++ + L RQ+ + ++ Q Q +K Q+ ++D
Sbjct: 621 KLLKLKESTERTVSKLNQEIWMMKNQRVQ-LMRQMKEDAEKFRQWKQKKDKEVIQLKERD 679
Query: 454 EL----LASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKT 509
L R+++K L R E AA +K+ LQ E V +K + K
Sbjct: 680 RKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQRE--VTDKRKETQSHGKE 737
Query: 510 RANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLL-LKDLGEIGGIIGTN 568
++ + L + + +T+ L +L +K A +++ L K+ E
Sbjct: 738 GIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRK 797
Query: 569 DVKTLADVNGVIEEEFTMARLYISKMKSEVK----SLVNRSKQLESAQMDSNRKM---NA 621
+L++V+G + E I +++E++ + + ++L A+ + K N
Sbjct: 798 CTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENI 857
Query: 622 SERELAACQL------LISQ--HEAKIK-SLTDYMQNMEQKRRQLEESQDSLSEELAKLR 672
+ A C L L+S H K++ SL + ++ L E Q+ SE +L+
Sbjct: 858 ATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQ 917
Query: 673 AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALE-------QQMESHREAHQKQLSRLRDEI 725
A+ E Q+K +++LQ+++ +K LE QQ+ S + ++L ++R+
Sbjct: 918 AELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVC 977
Query: 726 EEKQKIIDEIRDLNQKLQLEQ 746
E+ Q+++ E + QKL L Q
Sbjct: 978 EQNQQLLQENEIIKQKLILLQ 998
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 284 bits (726), Expect = 3e-76
Identities = 250/936 (26%), Positives = 434/936 (46%), Gaps = 72/936 (7%)
Query: 9 IKVMCRFRPLNEAEILRGDKFIPKF-KGDETVVIGQGKPYVFDRVLPPNTTQEQVYNACA 67
++V R RPL EI G + F G+ VV+G K + +D V P+T QE+V+N
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
Query: 68 KQIVKDVLEGYNGTIFAYGQTSSGKTHTMEG----KLHDPQLMGIIPRIAHDIFDHIYSM 123
++K V +GYN T+ AYGQT SGKT++M G + + +G+IPR+ +F I
Sbjct: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEI-DK 128
Query: 124 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181
+ EF +KVSY EIY ++I DLL S K + + ED + G TE+ V + +
Sbjct: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
Query: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ-ENVETEKKLSGKLYLVDLAGSEKVS 240
+++G +R VA T MN SSRSH+IF I+++Q + + KL+LVDLAGSE+
Sbjct: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQK 248
Query: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-THVPYRDSKMTRILQDSLGGNCRTT 299
KT AEG L E NIN+ L LGNVISAL + K VPYRDSK+TR+LQDSLGGN T
Sbjct: 249 KTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTL 308
Query: 300 IVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNV 359
++ C SP+ N ET +TL + RA+ IKN VN++ E LK
Sbjct: 309 MIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNH-----------LKQQ 357
Query: 360 IQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDE 419
+Q L++ L + +G +P I+ + +NL+ +++ +V EE EK
Sbjct: 358 VQQLQVLLLQ-AHGGTLP--GSITVEPSENLQ-----SLMEKNQSLV-----EENEKLSR 404
Query: 420 EISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEA 479
+S Q + I Q EK+ + L++ A+ + D +K+ E L +++
Sbjct: 405 GLSEAAGQTAQMLERIILTEQANEKMNAK-LEELRQHAACKLDLQKLVETLEDQELKENV 463
Query: 480 ------------AKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLT 527
DE + A + AV + + + + +R+++ T + A + ++
Sbjct: 464 EIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMS 523
Query: 528 TTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMA 587
EL++ L ++ T+ + L + I +++ +N E+E +
Sbjct: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEV---INLQKEKEELVL 580
Query: 588 RLYISKMKSEVKSLVNRSK----QLESAQMDSNRKMNASERELAACQLLISQHEAKIKSL 643
L +K + L R + +LE D +K+N + L L E + L
Sbjct: 581 ELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLK----LKESTERTVSKL 636
Query: 644 TDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKAL 703
++ M+ +R QL +E+ + + ++ + ++++++ L E +
Sbjct: 637 NQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQ 696
Query: 704 EQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDY--NKLKIEDQ 761
+ E RL+D +++++++ D+ ++ + ++ N++++
Sbjct: 697 SNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVS 756
Query: 762 EREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLF-----------VQDLT 810
E K LL D++ A++ + E+ S E R+ F +D
Sbjct: 757 TEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSI 816
Query: 811 TRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLR 870
T+ +S+E + + A Q+ L+ E K + + + +C L L L
Sbjct: 817 TKQIESLETEMEFRSAQIADLQQ-KLLDAESEDRPKQRWENIATILEAKCALKYLIGELV 875
Query: 871 ATAERVKALESALKEAKENAMRDRKRYQQEVDRIKE 906
++ +V LES+LK++K + +K +E + E
Sbjct: 876 SSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAE 911
Score = 67.8 bits (164), Expect = 5e-11
Identities = 96/460 (20%), Positives = 192/460 (41%), Gaps = 51/460 (11%)
Query: 343 KKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNI 402
K+K E E K+ Q E R R E + QI+ +K E + ++
Sbjct: 573 KEKEELVLELQTAKKDANQAKLSERRRKRLQEL---EGQIADLKKKLNEQSKLLKLKEST 629
Query: 403 APVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDEL----LAS 458
V+ ++ E + ++ + L RQ+ + ++ Q Q +K Q+ ++D L
Sbjct: 630 ERTVSKLNQEIRMMKNQRVQ-LMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLK 688
Query: 459 TRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDE 518
R+++K L R E AA +K+ LQ E+A + + T A ++ +
Sbjct: 689 LERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAA--RVKNW 746
Query: 519 LAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLL-LKDLGEIGGIIGTNDVKTLADVN 577
L + + +T+ L +L +K A ++ L K+ GE +L +V
Sbjct: 747 LGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVR 806
Query: 578 GVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASER------------- 624
G + E I +++E++ + L+ +D+ + +R
Sbjct: 807 GQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCA 866
Query: 625 ------ELAACQLLISQHEAKIK----SLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQ 674
EL + ++ +S+ E+ +K S D + + ++R E + L EL ++ Q
Sbjct: 867 LKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQ 926
Query: 675 EKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLR---DEIEEKQKI 731
Q+K L++LQ ++ +K LE ES E Q+ LS L+ +E+E+ +++
Sbjct: 927 H-------QEKVLYLLSQLQQSQMAEKQLE---ESVSEKEQQLLSTLKCQDEELEKMREV 976
Query: 732 IDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLL 771
++ NQ+L E E + L++ +++ + + LL
Sbjct: 977 CEQ----NQQLLRENEIIKQKLTLLQVASRQKHLPKDTLL 1012
Score = 53.9 bits (128), Expect = 7e-07
Identities = 104/544 (19%), Positives = 236/544 (43%), Gaps = 78/544 (14%)
Query: 338 TAEEWKKKYEKEKEKNK-----TLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKN--- 389
TA E + + E E ++ T ++ ++ +M +A+ E ++ K +N
Sbjct: 490 TAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQ 549
Query: 390 LEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQM 449
L+P DNI + + +KEK + L +L + NQ ++L+E+ ++++
Sbjct: 550 LQPIQYQ-YQDNIKELELEVINLQKEKEE-----LVLELQTAKKDANQ-AKLSERRRKRL 602
Query: 450 LDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKT 509
+ + +A ++ + Q +L +L+ E ++ + ++ ++ V ++ +E +K
Sbjct: 603 QELEGQIADLKKKLNE-QSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKF 661
Query: 510 RANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTND 569
R +Q D +E+ QL+E +KR E+L L ++ + ++
Sbjct: 662 RQWKQKKD-------------KEVIQLKE---RDRKRQYELLKLE-RNFQKQSNVL-RRK 703
Query: 570 VKTLADVNGVIEEEFTMARLYISKMK-----------SEVKSLVNRSKQLESAQMDSNRK 618
+ A N +++ R K K + VK+ + ++ + ++ R
Sbjct: 704 TEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRH 763
Query: 619 MNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRR-----------QLEESQDSLSEE 667
+N +L + +++Q A++K + +N K R Q+ ES+DS++++
Sbjct: 764 LN----DLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQ 819
Query: 668 LAKLRA------------QEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQ 715
+ L Q+K+ + +D+ K+ + E K AL+ + + +
Sbjct: 820 IESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLI-GELVSSK 878
Query: 716 KQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMK-LEKLLLLN 774
Q+S+L +++ + D+ + L E+ + +L+ E E + EK+L L
Sbjct: 879 IQVSKLESSLKQSKT---SCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLL 935
Query: 775 DKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKI 834
+ +Q++ K LEE+VS + Q L + K ++L ++++ E + + KQK+
Sbjct: 936 SQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEEL-EKMREVCEQNQQLLRENEIIKQKL 994
Query: 835 SFLE 838
+ L+
Sbjct: 995 TLLQ 998
Score = 42.7 bits (99), Expect = 0.002
Identities = 88/386 (22%), Positives = 162/386 (41%), Gaps = 70/386 (18%)
Query: 541 NHQKKRATEILNLLLKDLGEIGGIIGT------NDVKTLADVNGVIEEEFTMARLYISKM 594
NH K++ ++ LLL+ G G + G+ ++++L + N + EE +S+
Sbjct: 352 NHLKQQVQQLQVLLLQAHG--GTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEA 409
Query: 595 KSEVKSLVNRSKQLESAQMDSNRKMNASEREL---AACQLLISQ-----HEAKIKSLTDY 646
+ ++ R E A N KMNA EL AAC+L + + + ++K +
Sbjct: 410 AGQTAQMLERIILTEQA----NEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEI 465
Query: 647 MQNMEQKRRQL-EESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ 705
+ N++Q QL +E+ ++ + QE E S +R DA + AL Q
Sbjct: 466 ICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETS------PETSRSSDAFTTQHALRQ 519
Query: 706 QMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREM 765
S K+L L + K+ + ++ + +LQ Q + +D +E+
Sbjct: 520 AQMS------KELVELNKALALKEALARKMTQNDSQLQPIQ---------YQYQDNIKEL 564
Query: 766 KLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGG 825
+LE + L +K E E +T ++ N KL + R K+ EL+ G
Sbjct: 565 ELEVINLQKEKEELVLE-----LQTAKKDA----NQAKLSER----RRKRLQELE----G 607
Query: 826 GSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKE 885
A K+K+ N +L K+ + R + KL + +R + L +KE
Sbjct: 608 QIADLKKKL----NEQSKLLKLKESTERT-------VSKLNQEIRMMKNQRVQLMRQMKE 656
Query: 886 AKENAMRDRKRYQQEVDRIKEAVRAK 911
E + +++ +EV ++KE R +
Sbjct: 657 DAEKFRQWKQKKDKEVIQLKERDRKR 682
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 282 bits (722), Expect = 9e-76
Identities = 260/961 (27%), Positives = 459/961 (47%), Gaps = 99/961 (10%)
Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPK-FKGDETVVIGQGKPYVFDRVLPPNTTQEQVYN 64
E +KV R RPL E L + + + V+IG+ + + FD V N+TQ++VYN
Sbjct: 3 EIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYN 62
Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM----GIIPRIAHDIFDHI 120
C K +V ++EGYN T+FAYGQT SGKT+T+ G H ++ GIIPR +IF I
Sbjct: 63 TCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGG-HIASVVEGQKGIIPRAIQEIFQSI 121
Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNRVPYVKGCTERFVSSPE 178
S +++F++KVSY E+Y + +RDLL++ S +L + ED+ + G E V S
Sbjct: 122 -SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG 180
Query: 179 EVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ--ENVE--------TEKKLSGKL 228
EVM +++ G A RH T MNEHSSRSH+IF I+I Q +N+E + + + K
Sbjct: 181 EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF 240
Query: 229 YLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--THVPYRDSKMTR 286
+ VDLAGSE+V+KTG G E+ IN L ALGNVISAL + + +H+PYRD+K+TR
Sbjct: 241 HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR 300
Query: 287 ILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKY 346
+L+DSLGG+ +T ++ C SPS N E+ ++L + RA+ I+N +VN +
Sbjct: 301 LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVN-----------F 349
Query: 347 EKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQ-ISAKDQKNLEPCDNTPIIDNIAPV 405
E ++ I +E E+ R EA+ + +S Q N E +T I ++
Sbjct: 350 SPESDR-------IDEMEFEIKLLR--EALQSQQAGVSQTTQINREGSPDTNRIHSLEEQ 400
Query: 406 VAGIS---------TEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELL 456
VA + EE + ++ R + + ++ + + +++++ +L +
Sbjct: 401 VAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGI 460
Query: 457 ASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLT 516
T E+ + +T LQ++ E K + VL A E V ++QK EV++ + +
Sbjct: 461 GGT-ASLEEGPQHVTVLQLKRELKKCQC--VLAADE---VVFNQKELEVKELKNQVQMMV 514
Query: 517 DELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADV 576
E +L +E ++ L N + +++ L ++L ++ + ++ + D
Sbjct: 515 QENKGHAVSL----KEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDG 570
Query: 577 NGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAA----CQLL 632
+ R Y + + + + +S ++ ++ M + +R A Q+L
Sbjct: 571 P---DARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQML 627
Query: 633 ISQHEAKIKSL-TDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHE-VSFQDKEKEHL 690
+ E + K L + N + + + +E + + ++ + + V D + E
Sbjct: 628 LGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDE-- 685
Query: 691 TRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLS 750
T+ D E ++ ES QK + R E KQK+ + ++ K L +E +
Sbjct: 686 TQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIK 745
Query: 751 SDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLT 810
+ N K ++ +K+ K L EQA+ +L ++T L++L +DL+
Sbjct: 746 TG-NDAKSVSKQYSLKVTK---LEHDAEQAKVEL----------IETQKQLQELENKDLS 791
Query: 811 TRVKKSVELDNDDGGGSAAQKQKISFLENNLE----------QLTKVHKQLVRDNADLRC 860
V V+L + A K ++ L+ + Q K +L + ++
Sbjct: 792 D-VAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKY 850
Query: 861 ELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQE--VDRIKEAVRAKNMARRAH 918
+ +L+++LR E+ K L++ +K ++ + + QE + E + A N+ RR
Sbjct: 851 QKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKG 910
Query: 919 S 919
S
Sbjct: 911 S 911
Score = 63.2 bits (152), Expect = 1e-09
Identities = 94/442 (21%), Positives = 200/442 (45%), Gaps = 58/442 (13%)
Query: 475 IENEAAKDEVKEVLQALEELAVNYDQKSQEVE-DKTRANEQLTDELAQKTTTLTTTQREL 533
+E +DE ++ E+L ++ Q+SQE+ K + +E++ E QK
Sbjct: 677 VELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQK----------- 725
Query: 534 SQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGV----IEEEFTMARL 589
++EL+ + K + L+K+L + G ND K+++ + +E + A++
Sbjct: 726 --MRELTINIKMKED-----LIKELIKTG-----NDAKSVSKQYSLKVTKLEHDAEQAKV 773
Query: 590 YISKMKSEVKSLVNRS----KQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTD 645
+ + + +++ L N+ Q + +KM+A++ + Q Q K+ SL+
Sbjct: 774 ELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKK-QQDSKKLASLS- 831
Query: 646 YMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ 705
+QN E++ +LE+S D + + K++ Q K+ E + + K+ + + + + +K E
Sbjct: 832 -IQN-EKRANELEQSVDHMKYQ--KIQLQRKLREENEKRKQLDAVIK----RDQQKIKEI 883
Query: 706 QMESHREAHQKQLSRLRDEIEEKQK-----IIDEIRDLNQKLQLEQEKLSSDYNKLKIED 760
Q+++ +E K + D K++ ID ++ L+++ + E++ N+ + E
Sbjct: 884 QLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQ-EL 942
Query: 761 QEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHN-------LRKLFVQDLTTRV 813
+E E L+K + K+E ++ LE R Q L+ L Q+L+
Sbjct: 943 EELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELS--- 999
Query: 814 KKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATA 873
+K+V+L +++ L+ +QL K + + R P+ E L
Sbjct: 1000 EKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLE 1059
Query: 874 ERVKALESALKEAKENAMRDRK 895
E ++ALE+A++ E+ +K
Sbjct: 1060 EGIEALEAAIEYRNESIQNRQK 1081
Score = 62.0 bits (149), Expect = 3e-09
Identities = 114/531 (21%), Positives = 231/531 (43%), Gaps = 80/531 (15%)
Query: 315 KSTLMFGQRAKTIKNTVSVN---LELTAEEWKKKY-EKEKE----KNKTLKNVIQHLEME 366
K + G AK++ S+ LE AE+ K + E +K+ +NK L +V ++++
Sbjct: 741 KELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQ 800
Query: 367 LNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYR 426
+ +A Q+ K Q++ + +A +S + +++ +E S+
Sbjct: 801 KEFRKKMDAAKLRVQVLQKKQQDSKK-------------LASLSIQNEKRANELEQSV-- 845
Query: 427 QLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQE-ELTRLQIENEAAKDEVK 485
D Q+ QL KL+++ + +L A +RD +KI+E +L Q E K E
Sbjct: 846 -----DHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDL 900
Query: 486 EV---------------LQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQ 530
+ LQ L+E D++ ++V ++ + E+L +L ++ ++ +
Sbjct: 901 DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE 960
Query: 531 RELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLY 590
L + L N +K R+++ LN T+ +K +N ++E+E + +
Sbjct: 961 ALLQEKSHLEN-KKLRSSQALN--------------TDSLKISTRLN-LLEQELSEKNVQ 1004
Query: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 650
+ +E K+ ++ ++ + D +K + E ++S E + L + +
Sbjct: 1005 LQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHV--LFQLEEGI 1062
Query: 651 EQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ---QM 707
E +E +S+ LRA H +S + E++ L + ++
Sbjct: 1063 EALEAAIEYRNESIQNRQKSLRA--SFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKV 1120
Query: 708 ESHREAHQKQLSRLRDEIEEKQKIIDE---IRDLNQKLQLEQEKLSSDYNKLKIEDQERE 764
+ REA +KQ +L +E E K K+++ +R+L L+ KL D +L ++ +E E
Sbjct: 1121 VNLREAERKQ--QLYNE-EMKMKVLERDNMVRELES--ALDHLKLQCD-RRLTLQQKEHE 1174
Query: 765 MKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKK 815
K++ LLL+ +EQ E + +T ++Q L + L+ T+R K
Sbjct: 1175 QKMQ--LLLHHFKEQDGEGIMETFKTYEDKIQQLE--KDLYFYKKTSRDHK 1221
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 281 bits (718), Expect = 3e-75
Identities = 243/913 (26%), Positives = 430/913 (47%), Gaps = 128/913 (14%)
Query: 4 PAECSIKVMCRFRPLNEAEILRGDKFIPKFK-GDETVVIGQGKPYVFDRVLPPNTTQEQV 62
P E S++V R RP E + G G+ V +G+ K + FD V ++ QEQ+
Sbjct: 5 PDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQI 64
Query: 63 YNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL----MGIIPRIAHDIFD 118
Y C +++++ EGYN T+FAYGQT +GKT+TM G D + +GII R +F
Sbjct: 65 YIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEELGIISRAVKHLFK 123
Query: 119 HI-----YSMDENL---EFHIKVSYFEIYLDKIRDLLDVS--------KTNLAVHEDKNR 162
I ++ L +F + + E+Y +++ DL D + K+N+ +HED
Sbjct: 124 SIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTG 183
Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENV---- 218
Y G T R V++ E+M + G +R A T MN SSRSH+IF I++ Q V
Sbjct: 184 GIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQI 243
Query: 219 ----ETEKK-------------LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSA 261
T+ K L+ K + VDLAGSE++ +TGA G E +IN L A
Sbjct: 244 DADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLA 303
Query: 262 LGNVISALAEGTK--THVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLM 319
LGNVISAL + +K THVPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +TL
Sbjct: 304 LGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLK 363
Query: 320 FGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPED 379
+ RA+ IKN V VN ++ ++ L++ I L+MEL ++ G+ + ++
Sbjct: 364 YANRARNIKNKVMVN-----------QDRASQQINALRSEITRLQMELMEYKTGKRIIDE 412
Query: 380 EQISA------------KDQKNL--------EPCDN-----TPIIDNIAPVVAGISTEEK 414
E + + + NL E D T ++ + A V + E
Sbjct: 413 EGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGN 472
Query: 415 EKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQ 474
E+ I S ++++D ++ + + E L++ + A+ R Y +
Sbjct: 473 EEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNL-----TRATARAPYFSGSSTFSPTI 527
Query: 475 IENEAAKDEVKEVLQA-LEELAVNYDQKSQEV---EDKTRANEQLTDELAQKTTTLTTTQ 530
+ ++ E+ ++ + LE+L +K + V ED T +++ +E + + +
Sbjct: 528 LSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEE--KGVSERENNE 585
Query: 531 RELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLY 590
E+ + QE+S+H+ + E ++ +I G +++ + +D + +
Sbjct: 586 LEVEESQEVSDHEDEEEEE-----EEEEDDIDGGESSDESDSESDEKANYQADLANITCE 640
Query: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 650
I+ + + L N K+L++ + K+ + ++ QL Q + S+ Y +
Sbjct: 641 IAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEK 700
Query: 651 EQK-RRQLEESQDSLSEELAKLRAQEKMHE--VSFQDKEKEHLTRL-QDAEEMKKALEQQ 706
+K R + E+ ++++EL +L+A +K H + Q + ++ L +L QD EMKK +
Sbjct: 701 AKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRL 760
Query: 707 MESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMK 766
M+ +E E+++ + E R + QL++++ D+ +E Q+R +
Sbjct: 761 MKQMKE-------------EQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQE 807
Query: 767 LEKLLLLNDKREQA---REDLKGLEETVSRELQTLHNLRKLFVQDLTTR--VKKSVELDN 821
++L K E+ R ++ + + V+ ++ RKL D + + ++
Sbjct: 808 ----VVLRRKTEEVTALRRQVRPMSDKVAGKV-----TRKLSSSDAPAQDTGSSAAAVET 858
Query: 822 DDGGGSAAQKQKI 834
D A QK +I
Sbjct: 859 DASRTGAQQKMRI 871
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 274 bits (700), Expect = 3e-73
Identities = 267/936 (28%), Positives = 436/936 (46%), Gaps = 111/936 (11%)
Query: 45 KPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP- 103
K + FD V +TTQE V+ AK IV+ + GYNGTIFAYGQT SGKT TM G
Sbjct: 68 KTFTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDN 127
Query: 104 ---QLMGIIPRIAHDIFDHIYSMDENL----EFHIKVSYFEIYLDKIRDLLDVSKTNLAV 156
L G+IPR +F I E F K S+ EIY ++I DLLD + L +
Sbjct: 128 FSHNLRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYL 187
Query: 157 HEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIK-- 214
E + +V G E+ V+S E V+ G NR VA T+MN SSRSH++F I I+
Sbjct: 188 REHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESM 247
Query: 215 QENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE--- 271
+++ E + L LVDLAGSE+ T AEG L EA NIN+SLS LG VI+AL +
Sbjct: 248 EKSNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGN 307
Query: 272 GTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTV 331
G + HV YRDSK+T +L+DSLGGN +T I+ P ET STL F QRAK IKN
Sbjct: 308 GKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKA 367
Query: 332 SVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLE 391
VN E + L+ ++ L+ +L +G+ P E +D+K
Sbjct: 368 VVN------------EDTQGNVSQLQAEVKRLKEQLAELASGQTPP--ESFLTRDKKK-- 411
Query: 392 PCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQML- 450
N A + S +EK+ E+++ L L K ++ Q +++ K ++ +
Sbjct: 412 --TNYMEYFQEAMLFFKKSEQEKKSLIEKVTQL-EDLTLKKEKFIQSNKMIVKFREDQII 468
Query: 451 ----------------DQDELLASTRRDYEKIQEEL------TRLQIENEAAKDEVKEVL 488
+QD LL+ R + + ++E++ + +EN + ++E + L
Sbjct: 469 RLEKLHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRR-L 527
Query: 489 QALEELAVNYDQKSQEVE------------DKTRANEQLTDELAQKTTTLTTT----QRE 532
+ LE + + +Q + +K+ N+Q AQK L + +
Sbjct: 528 RLLEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQ 587
Query: 533 LSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYIS 592
L Q+Q N+ K+ E L K E+ + + K ++ ++E R +S
Sbjct: 588 LLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQ-KANLNLENLLEATKACKRQEVS 646
Query: 593 KM-KSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNME 651
++ K ++L + ++ Q+ S R + E+ + L +Q+ + L + + N
Sbjct: 647 QLNKIHAETLKIITTPTKAYQLHS-RPVPKLSPEMGSFGSLYTQNSS---ILDNDILNEP 702
Query: 652 QKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHR 711
E++ +++SEEL ++ Q + ++E ++L Q + ++E H
Sbjct: 703 VPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVD--------KLEHHS 754
Query: 712 EAHQKQLSRLR-DEIEEKQKIIDEIRDLNQKLQLEQEK---LSSDYNKLKI--EDQEREM 765
Q+ S R D +++++++ ++ L ++LQ Q K L S+ + L++ ++E+
Sbjct: 755 TQMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKEL 814
Query: 766 KLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGG 825
KL + K Q +E K E + +LQ L NLR + L ++ DN
Sbjct: 815 SSVKLEYSSFKTNQEKEFNKLSERHMHVQLQ-LDNLRLENEKLLESKACLQDSYDN---- 869
Query: 826 GSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKE 885
Q+I E ++QL++ + ++N L+ +L L + L A ER L +E
Sbjct: 870 -----LQEIMKFE--IDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEE 922
Query: 886 AKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQ 921
KEN+ +E+ ++ EAVR + A Q
Sbjct: 923 DKENS-------SKEILKVLEAVRQEKQKETAKCEQ 951
Score = 74.3 bits (181), Expect = 5e-13
Identities = 95/490 (19%), Positives = 206/490 (42%), Gaps = 78/490 (15%)
Query: 411 TEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEEL 470
+EE E++S+L +LD+++ + + Q +KL+ EL +S R D+ K QEEL
Sbjct: 716 SEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEEL 775
Query: 471 TRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKT----RANEQLTDELAQKTTTL 526
++ + + L+E D EV D A+++L+ + ++
Sbjct: 776 L----------SQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFK 825
Query: 527 TTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTM 586
T ++E ++L E H + ++ NL L++ + L + +++ +
Sbjct: 826 TNQEKEFNKLSERHMHVQ---LQLDNLRLEN-------------EKLLESKACLQDSYDN 869
Query: 587 ARLYISKMKSEV----KSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKS 642
+ MK E+ ++L N K+ E+ + D N M E E
Sbjct: 870 LQ---EIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAE----------------- 909
Query: 643 LTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKA 702
+ + Q EE +++ S+E+ K+ + + K ++ + ++Q EE A
Sbjct: 910 ----KERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLA 965
Query: 703 LEQ---QMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIE 759
E+ +E R++ +K ++ L ++I+E + + E + L+ E + ++ YN ++
Sbjct: 966 TEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVD 1025
Query: 760 DQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVEL 819
+E + ++K D+ L+ET+ + + R + +DL ++ L
Sbjct: 1026 REESRVLIKK----------QEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNML 1075
Query: 820 DNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 879
+ A K+ L++ E+LTK + L + ++E++ +++ L
Sbjct: 1076 -------TEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQL 1128
Query: 880 ESALKEAKEN 889
E + A E+
Sbjct: 1129 EHVMDSAAED 1138
Score = 55.1 bits (131), Expect = 3e-07
Identities = 89/477 (18%), Positives = 203/477 (42%), Gaps = 68/477 (14%)
Query: 335 LELTAEEWKKKYEKEKEKNKTLKNVIQHLE--MELNRWRNGEA---VPEDEQISAKD--- 386
++ ++ + + K++N+TLK+ + +L +E + RN + ED++ S+K+
Sbjct: 874 MKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILK 933
Query: 387 ---------QKNLEPCDNT-----PIIDNIAPVVAGISTEEKEKYDEE--ISSLYRQLDD 430
QK C+ + +++ IS+ EK + ++ ++ L Q+ +
Sbjct: 934 VLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQE 993
Query: 431 KDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQA 490
+ ++++ + LKQ++ D + S D E+ + + + +++ K+ ++ L+
Sbjct: 994 LRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVDILDLKETLR--LRI 1051
Query: 491 LEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQ----LQELSNHQKKR 546
L E + D +++ T LT+ + + L + Q EL++ +QEL + ++
Sbjct: 1052 LSE-DIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQK 1110
Query: 547 ATEI------LNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKS 600
E+ N ++ L + + + + +++K+ +
Sbjct: 1111 KEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPH---------FQTHLAKLLETQEQ 1161
Query: 601 LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEES 660
+ + +++ K+N +RE+ ++L ++K M+N+ + +QL E
Sbjct: 1162 EIEDGRASKTSLEHLVTKLN-EDREVKNAEIL------RMKEQLREMENLRLESQQLIEK 1214
Query: 661 QDSLSEELAKLRAQEKMHEVSFQDKE----------KEHLTRLQDAEEMKKALEQQMESH 710
L +L ++ Q++ + + D + KE L + + EEM K E
Sbjct: 1215 NWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQ 1274
Query: 711 REAHQKQLSRLR--DEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREM 765
+ K++ LR DE+E Q + E + +K QL + KL Y + + QE EM
Sbjct: 1275 SALYNKEMECLRMTDEVERTQTL--ESKAFQEKEQL-RSKLEEMYEERERTSQEMEM 1328
Score = 44.3 bits (103), Expect = 6e-04
Identities = 68/383 (17%), Positives = 154/383 (40%), Gaps = 38/383 (9%)
Query: 351 EKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGIS 410
EK +T+ + Q L+ ++ + E+ ++ K Q+ I+D + I
Sbjct: 1000 EKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQE-------VDILDLKETLRLRIL 1052
Query: 411 TE--EKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQE 468
+E E++ E+++ QL+ + + S L + ++++ ++ L+ + + +E
Sbjct: 1053 SEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKE 1112
Query: 469 ELTRLQIENEAAKDEVKEVLQALEE--------------LAVNYDQKSQEVEDKTRANEQ 514
E+ + + E +++ V+ + E LA + + QE+ED +
Sbjct: 1113 EVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTS 1172
Query: 515 LTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLA 574
L + + E+ +++E + E L+ K+ G + K +
Sbjct: 1173 LEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENS 1232
Query: 575 DVNGVI-------EEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELA 627
D N +EE RL SK+ E+ + ++++SA + + E+
Sbjct: 1233 DQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVE 1292
Query: 628 ACQLLIS-------QHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHE- 679
Q L S Q +K++ + + + Q+ L + + L+EE KL + +H+
Sbjct: 1293 RTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEENGKLVGHQNLHQK 1352
Query: 680 VSFQDKEKEHLTRLQDAEEMKKA 702
+ + + K+ RL + E +A
Sbjct: 1353 IQYVVRLKKENVRLAEETEKLRA 1375
Score = 39.7 bits (91), Expect = 0.014
Identities = 52/231 (22%), Positives = 104/231 (45%), Gaps = 28/231 (12%)
Query: 347 EKEKEKNKTLKNVIQHLEMELNRWR---NGEAVPEDEQISAKDQKNLEPCDNTPIIDNIA 403
E+E E + K ++HL +LN R N E + EQ+ + LE + +I+
Sbjct: 1160 EQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLE---SQQLIEKNW 1216
Query: 404 PVVAGIST--EEKEKYDEEISSLYRQLDDKDDEINQQ---SQLAEKLKQQMLDQDEL--- 455
+ + +KE D+ + +++++ I ++ S++ E++ + D +E+
Sbjct: 1217 LLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSA 1276
Query: 456 LASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQL 515
L + + ++ +E+ R Q A E +++ LEE+ ++ SQE+E + E L
Sbjct: 1277 LYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECL 1336
Query: 516 TDE---------LAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKD 557
+E L QK + ++E +L E +K RA N+ LK+
Sbjct: 1337 AEENGKLVGHQNLHQKIQYVVRLKKENVRLAE--ETEKLRAE---NVFLKE 1382
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 270 bits (690), Expect = 5e-72
Identities = 265/925 (28%), Positives = 421/925 (45%), Gaps = 118/925 (12%)
Query: 8 SIKVMCRFRPLNEAEILRGDKFIPK---FKGDETVVIG------QGKPYVFDRVLPPNTT 58
+I+V+ R RP N AE I + + + +V G K Y FD V +T
Sbjct: 18 NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTK 77
Query: 59 QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKL---------HDPQLMGII 109
Q VY + I+ +V+ GYN TIFAYGQT +GKT TMEG+ DP L GII
Sbjct: 78 QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP-LAGII 136
Query: 110 PRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLL----DVSKTNLAVHEDKN-RVP 164
PR H IF+ + D EF +KVS EIY +++ DLL DVS+ + +N R
Sbjct: 137 PRTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGV 194
Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINI--KQENVETEK 222
+KG E V + +EV ++++G A R A T MN +SSRSHS+F + I K+ ++ E+
Sbjct: 195 IIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEE 254
Query: 223 KLS-GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRD 281
+ GKL LVDLAGSE + ++GA EA NIN+SL LG VI+AL E T HVPYR+
Sbjct: 255 LVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTP-HVPYRE 313
Query: 282 SKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEE 341
SK+TRILQDSLGG RT+I+ SP+ N ET STL + RAK I N VN +LT +
Sbjct: 314 SKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKA 373
Query: 342 WKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDN 401
K+Y +E E+ K ++ R +NG + E+ + ++ +I+
Sbjct: 374 LIKEYTEEIERLKR--------DLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEK 425
Query: 402 IAPVVAGIS--TEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLAST 459
I V ++ TE E+ L +K E+ + ++ K Q++ ++ + ++
Sbjct: 426 IGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSAL 485
Query: 460 RRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRAN------- 512
EK+ + ++L E +V + L+ DQ + E +D N
Sbjct: 486 ESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKA-VDQHNAEAQDIFGKNLNSLFNN 544
Query: 513 -EQLTDELAQKTTTL--------------------TTTQRELSQLQELSNHQKKRATEIL 551
E+L + + K + T T L L + + ++I
Sbjct: 545 MEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIF 604
Query: 552 NLLLKD----------LGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSL 601
N++LK+ L E+ ++ T D+ +E + + I K+ S++K +
Sbjct: 605 NMILKEQSLAAESKTVLQELINVLKT-------DLLSSLEMILSPTVVSILKINSQLKHI 657
Query: 602 VNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQ 661
S + D ++++ L C L E I SL + + L+ +
Sbjct: 658 FKTSLTVADKIEDQKKELDGFLSIL--CNNLHELQENTICSLVESQKQCGNLTEDLKTIK 715
Query: 662 DSLSEELAKLRAQEKMHEVSFQDK----EKEHLTRLQDAEEMKKALEQQMESHRE---AH 714
+ S+EL KL + ++K +K + ++ ++ K + +M H + A
Sbjct: 716 QTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCAD 775
Query: 715 QKQLSR-LRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLL 773
S+ LR+ +E K+++E + KL EK+S QE E + E L
Sbjct: 776 SDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKIS----------QETEQRCES---L 822
Query: 774 NDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQK 833
N + E +++ Q LHNL ++ Q S + DG +A +KQ
Sbjct: 823 NTRTVYFSEQ---WVSSLNEREQELHNLLEVVSQ--CCEASSSDITEKSDGRKAAHEKQH 877
Query: 834 ISFLENNLEQLTKVHKQLVRDNADL 858
F L+Q+T +L+ N +L
Sbjct: 878 NIF----LDQMTIDEDKLIAQNLEL 898
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 267 bits (683), Expect = 3e-71
Identities = 238/914 (26%), Positives = 411/914 (44%), Gaps = 106/914 (11%)
Query: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFK-GDETVVIGQGKPYVFDRVLPPNTTQ 59
MA +C +KV R RP E + G G+ V++G+ K + +D V +T Q
Sbjct: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
Query: 60 EQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH---DPQLMGIIPRIAHDI 116
EQ+Y+ C ++++ EGYN T+ AYGQT +GKT+TM + GIIPR +
Sbjct: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
Query: 117 FDHIYSMDENL--------EFHIKVSYFEIYLDKIRDLLDVSK--------TNLAVHEDK 160
F I EF + + E+Y ++I DL D ++ +N+ +HED
Sbjct: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
Query: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 220
N Y G T R + S EE++ + +G +R A T MN SSRSH+IF I++ Q + T
Sbjct: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
Query: 221 E---------------------KKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSL 259
+ + L+ K + VDLAGSE++ +TGA G E +IN L
Sbjct: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
Query: 260 SALGNVISALAEGTK--THVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKST 317
ALGNVISAL + +K HVPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +T
Sbjct: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
Query: 318 LMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVP 377
L + RA+ IKN V VN +K ++ L+ I L+MEL ++ G+ V
Sbjct: 361 LKYANRARNIKNKVVVN-----------QDKTSQQISALRAEIARLQMELMEYKAGKRVI 409
Query: 378 EDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQ 437
++ E + +E + ++ +D ++ + Q
Sbjct: 410 GEDGAEGYSDLFRE---------------NAMLQKENGALRLRVKAMQEAIDAINNRVTQ 454
Query: 438 -QSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAV 496
SQ A L + D +E + + ++Y + EEL +E+EA + ++ L +
Sbjct: 455 LMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARS- 513
Query: 497 NYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLK 556
Y + + + E A + E + +E+ +K E K
Sbjct: 514 PYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAK 573
Query: 557 DLGEIGGIIGTNDV---KTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQM 613
E N+ + D +G EEE R + +SLV+ E ++
Sbjct: 574 LQQENSEETDENEAEEEEEERDESGCEEEE---GREDEDEDSGSEESLVDSDSDPEEKEV 630
Query: 614 DSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKR-------RQLEESQDSLSE 666
+ + E+ Q LI + E + L E+K R + +D + +
Sbjct: 631 NFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQ 690
Query: 667 ELAKLR--AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ--QMESHREAHQKQLSRLR 722
L+ + +EK +++ D EK +D ++++ A ++ ++ ++ ++++L +L+
Sbjct: 691 NLSTMECYTEEKANKIK-ADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQ 749
Query: 723 DEIEEKQK----IIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKRE 778
E+ E +K ++ ++R+ Q+ +L + K + + +LK E + +E ++ L + KR+
Sbjct: 750 AEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIR--ALESQKRQ 807
Query: 779 QAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDND--DGGGSAAQKQKISF 836
Q E + R+ Q + LR+L + ++ RV L D G + S
Sbjct: 808 Q--------EMVLRRKTQEVSALRRL-AKPMSERVAGRAGLKPPMLDSGAEVSASTTSSE 858
Query: 837 LENNLEQLTKVHKQ 850
E+ ++ + +Q
Sbjct: 859 AESGARSVSSIVRQ 872
Score = 69.3 bits (168), Expect = 2e-11
Identities = 112/479 (23%), Positives = 198/479 (41%), Gaps = 55/479 (11%)
Query: 506 EDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEIL----NLLLKDLGEI 561
ED L E A + + +QE + R T+++ NLLL G+
Sbjct: 411 EDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDG 470
Query: 562 GGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNA 621
IG + ++ EE L M ++ + L A S + A
Sbjct: 471 NEAIGALIQNYIREI-----EELRTKLLESEAMNESLR------RSLSRASARSPYSLGA 519
Query: 622 SERELAACQLLISQHEAKIKSLTDYMQNMEQ-KRRQLEESQDSLSEELAKLRA---QEKM 677
S A S E + + Q++E+ K++++ + + S +E K RA QE
Sbjct: 520 SPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENS 579
Query: 678 HEVSFQDKEKEHLTR----------LQDAEEMKKALEQQMESHREAHQKQ------LSRL 721
E + E+E R +D +E + E ++S + +K+ L+ L
Sbjct: 580 EETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADL 639
Query: 722 RDEIEEKQKIIDEIRDLNQKLQL----EQEKLSSDYNKLKIEDQEREMKLEKLLLL---- 773
EIE KQK+IDE+ + ++LQ +EKL NK++ ER+ L+ L +
Sbjct: 640 TCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYT 699
Query: 774 NDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQK 833
+K + + D + ++R+LQ L +K + L + + EL + +K K
Sbjct: 700 EEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAK 759
Query: 834 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 893
++ ++ E+ + ++LV + E+ +L+K R +++ALES K +E +R
Sbjct: 760 VALMKQMREE--QQRRRLVETKRNR--EIAQLKKEQRRQEFQIRALESQ-KRQQEMVLR- 813
Query: 894 RKRYQQEVDRIKEAVRAKNMARRAHSAQIAKP--IRPGHYPASSPTAVHAIRGGGGSSS 950
R QEV ++ AK M+ R KP + G ++S T+ A G SS
Sbjct: 814 --RKTQEVSALRRL--AKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSS 868
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 261 bits (666), Expect = 3e-69
Identities = 184/482 (38%), Positives = 259/482 (53%), Gaps = 32/482 (6%)
Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGD----ETVVIGQG------KPYVFDRVLPPNT 57
++KV+ R RP+N+ E R + P D + + G K + FD +
Sbjct: 5 AVKVVVRCRPMNQRE--RELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDH 62
Query: 58 TQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIF 117
EQ+YN A +V+ V EGYNGTIFAYGQT SGK+ TM+G P GIIPR +F
Sbjct: 63 VTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVF 122
Query: 118 DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLAVHEDKNRVPYVKGCTERFVSS 176
+ + EN +F ++ SY EIY + +RDLL +K L + E + YVKG + V S
Sbjct: 123 ESVQCA-ENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHS 181
Query: 177 PEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK---LSGKLYLVDL 233
+ +++ G NR V T MN+ SSRSHSIF I+I+ V+ K +GKL LVDL
Sbjct: 182 VAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDL 241
Query: 234 AGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLG 293
AGSE+ SKTGA G L EA IN SLSALGNVISAL +G HVPYRDSK+TR+LQDSLG
Sbjct: 242 AGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLG 301
Query: 294 GNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKN 353
GN +T +V C SP+ N ET STL + RAK I+N +N E + ++Y++E +K
Sbjct: 302 GNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN-EDPKDALLREYQEEIKKL 360
Query: 354 KTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEE 413
K + Q L+ + + P+ Q+ K L P P+I + + EE
Sbjct: 361 KAILTQ-QMSPSSLSALLSRQVPPDPVQVEEK----LLP---QPVIQHDVEAEKQLIREE 412
Query: 414 KEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRL 473
Y+E ++ L D E +++L E + D L++ + K E + ++
Sbjct: 413 ---YEERLARLKA---DYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVLQV 466
Query: 474 QI 475
+
Sbjct: 467 GV 468
Score = 35.4 bits (80), Expect = 0.26
Identities = 32/122 (26%), Positives = 63/122 (51%), Gaps = 13/122 (10%)
Query: 668 LAKLRAQEKM----HEVSFQDKEKEHLTRLQDAEEMKKALEQQME-SHREAHQKQLSRLR 722
LA+L+ E+ + +D +++H R + A+E +K L ++ S ++ L +
Sbjct: 742 LARLQLLEQQVVGGEQAKNKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLLNVY 801
Query: 723 DEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQARE 782
D I+E E+R ++ L+ Q KL + +++I+D + E +LEK+ L R Q R+
Sbjct: 802 DSIQE------EVRAKSKLLEKMQRKLRAA--EVEIKDLQSEFQLEKIDYLATIRRQERD 853
Query: 783 DL 784
+
Sbjct: 854 SM 855
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 261 bits (666), Expect = 3e-69
Identities = 184/482 (38%), Positives = 259/482 (53%), Gaps = 32/482 (6%)
Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGD----ETVVIGQG------KPYVFDRVLPPNT 57
++KV+ R RP+N+ E R + P D + + G K + FD +
Sbjct: 5 AVKVVVRCRPMNQRE--RELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDH 62
Query: 58 TQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIF 117
EQ+YN A +V+ V EGYNGTIFAYGQT SGK+ TM+G P GIIPR +F
Sbjct: 63 VTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVF 122
Query: 118 DHIYSMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLAVHEDKNRVPYVKGCTERFVSS 176
+ + EN +F ++ SY EIY + +RDLL +K L + E + YVKG + V S
Sbjct: 123 ESVQCA-ENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHS 181
Query: 177 PEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK---LSGKLYLVDL 233
+ +++ G NR V T MN+ SSRSHSIF I+I+ V+ K +GKL LVDL
Sbjct: 182 VAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDL 241
Query: 234 AGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLG 293
AGSE+ SKTGA G L EA IN SLSALGNVISAL +G HVPYRDSK+TR+LQDSLG
Sbjct: 242 AGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLG 301
Query: 294 GNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKN 353
GN +T +V C SP+ N ET STL + RAK I+N +N E + ++Y++E +K
Sbjct: 302 GNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN-EDPKDALLREYQEEIKKL 360
Query: 354 KTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEE 413
K + Q L+ + + P+ Q+ K L P P+I + + EE
Sbjct: 361 KAILTQ-QMSPSSLSALLSRQVPPDPVQVEEK----LLP---QPVIQHDVEAEKQLIREE 412
Query: 414 KEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRL 473
Y+E ++ L D E +++L E + D L++ + K E + ++
Sbjct: 413 ---YEERLARLKA---DYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVLQV 466
Query: 474 QI 475
+
Sbjct: 467 GV 468
Score = 35.4 bits (80), Expect = 0.26
Identities = 32/122 (26%), Positives = 63/122 (51%), Gaps = 13/122 (10%)
Query: 668 LAKLRAQEKM----HEVSFQDKEKEHLTRLQDAEEMKKALEQQME-SHREAHQKQLSRLR 722
LA+L+ E+ + +D +++H R + A+E +K L ++ S ++ L +
Sbjct: 742 LARLQLLEQQVVGGEQAKNKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLLNVY 801
Query: 723 DEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQARE 782
D I+E E+R ++ L+ Q KL + +++I+D + E +LEK+ L R Q R+
Sbjct: 802 DSIQE------EVRAKSKLLEKMQRKLRAA--EVEIKDLQSEFQLEKIDYLATIRRQERD 853
Query: 783 DL 784
+
Sbjct: 854 SM 855
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 259 bits (661), Expect = 1e-68
Identities = 270/960 (28%), Positives = 435/960 (45%), Gaps = 128/960 (13%)
Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKP--------------------- 46
S+KV R RP+N E KFI + + +T + P
Sbjct: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
Query: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106
Y D P +QE V+ +VK EGYN +FAYGQT SGK++TM G D
Sbjct: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Query: 107 GIIPRIAHDIFDHIYSMD--ENLEFHIKVSYFEIYLDKIRDLL--DVSKT-NLAVHEDKN 161
G+IPRI +F I + F +VSY EIY +++RDLL SKT NL V E
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
Query: 162 RVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE 221
PYV+ ++ V + +V +++D G NR A T MN+ SSRSH+IF I Q ++E
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSE 239
Query: 222 KKLS--GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK----- 274
K++LVDLAGSE+ TGA G L E NINKSL LGNVISALA+ ++
Sbjct: 240 MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANT 299
Query: 275 ------THVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIK 328
VPYRDS +T +L+DSLGGN +T ++ SP+ N ET STL + RAK I
Sbjct: 300 LAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNII 359
Query: 329 NTVSVN--------LELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDE 380
N ++N EL AE + K + L + L ME +N V +
Sbjct: 360 NKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARV---Q 416
Query: 381 QISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQ 440
+++ + N +A GI D E+ L DD++
Sbjct: 417 ELTKEWTNKWNETQNILKEQTLALRKEGIGV----VLDSELPHLI----GIDDDLLSTGI 468
Query: 441 LAEKLK--QQMLDQDELLASTRRDYEKIQEELTRLQIENE-AAKDEVKEVLQALEELAVN 497
+ LK Q + +D+ AST +D L L +E+E + + + +
Sbjct: 469 ILYHLKEGQTYVGRDD--ASTEQDI-----VLHGLDLESEHCIFENIGGTVTLIPLSGSQ 521
Query: 498 YDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKD 557
++ + T N+ L + +E ++L+E +K +L + D
Sbjct: 522 CSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLRE---KRKSGLLSSFSLSMTD 578
Query: 558 LGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNR 617
L + ++ + N +E E R + K++S+ K + ++ +S + + R
Sbjct: 579 LSK-----SRENLSAVMLYNPGLEFE-RQQREELEKLESKRKLIEEMEEKQKSDKAELER 632
Query: 618 ---KMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQ 674
++ +E QL I + E +K + +++N K + L ++ EE +LR Q
Sbjct: 633 MQQEVETQRKETEIVQLQIRKQEESLKRRSFHIEN---KLKDLLAEKEKFEEE--RLREQ 687
Query: 675 EKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDE 734
+ E+ Q K +E T L+ EE+++ +++ ++ +A + Q+ + E+++ QK DE
Sbjct: 688 Q---EIELQKKRQEEETFLRVQEELQRL--KELNNNEKAEKFQIFQ---ELDQLQKEKDE 739
Query: 735 IRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLL---LNDKREQAREDLKGLEETV 791
KL+LE+++L E+QE+E + L L +K+E + +G + V
Sbjct: 740 ---QYAKLELEKKRL---------EEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWV 787
Query: 792 SRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQL 851
E + L +R+ + RVK++ ++D G +K ++ F E QL K L
Sbjct: 788 EEEKRDLEGIRESLL-----RVKEARAGGDED--GEELEKAQLRFFEFKRRQLVK----L 836
Query: 852 VRDNADLRCELPKLEKRLRATAERVKAL------ESALKEAKENAMRDRKRYQQEVDRIK 905
V DL + L+K ++ E ++ L ES L E + ++ D Q+ ++IK
Sbjct: 837 VNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIK 896
Score = 78.6 bits (192), Expect = 3e-14
Identities = 136/606 (22%), Positives = 254/606 (41%), Gaps = 86/606 (14%)
Query: 340 EEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPII 399
E +K E+ +EK K+ K ++ ++ E+ R + Q+ + Q+ + I
Sbjct: 610 ESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIV---QLQIRKQEESLKRRSFHIE 666
Query: 400 DNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLAST 459
+ + ++A EKEK++EE + +Q ++ + K+Q
Sbjct: 667 NKLKDLLA-----EKEKFEEE-------------RLREQQEIELQKKRQ----------E 698
Query: 460 RRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVE-DKTRANEQLTDE 518
+ ++QEEL RL+ N K E ++ Q L++L D++ ++E +K R EQ ++
Sbjct: 699 EETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQ 758
Query: 519 LAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDL-GEIGGIIGTNDVKTLADVN 577
+ + + +L + QE+ ++ + + +DL G ++ + + D +
Sbjct: 759 V----MLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDED 814
Query: 578 GVIEEEFTMARLYISKMK-SEVKSLVNRSKQLESAQMDSNRKMNASERELAAC------- 629
G EE A+L + K ++ LVN K L Q D +K E+E+ C
Sbjct: 815 G---EELEKAQLRFFEFKRRQLVKLVNLEKDLVQ-QKDILKKEVQEEQEILECLKCEHDK 870
Query: 630 -QLLISQHEAKIKSLTDYMQNME-----QKRRQLEESQ-DSLSEELAKLRAQEKMHEVSF 682
L+ +H+ + +T+ Q+ E + R Q +E Q L + +EK
Sbjct: 871 ESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEI 930
Query: 683 QDKEKEHL--TRLQDAEEMKKALEQQMESHREAHQKQ-----------LSRLRDEIEEKQ 729
D+ L T Q +EM++ EQ + A+Q Q ++R +++ +K+
Sbjct: 931 LDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKE 990
Query: 730 KIIDEIRDLNQKLQLEQ-----EKLSSDYNKLKIEDQEREMKLEKLLLLND-KREQARED 783
K I E R+ Q+ LE+ E+ S + E E + +KL LN REQ+
Sbjct: 991 KEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQS--- 1047
Query: 784 LKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELD--NDDGGGSAAQKQKISFLENNL 841
GL+ ++ E + L ++ ++ +K E+D D G+ K S L +
Sbjct: 1048 --GLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSA 1105
Query: 842 EQLTKVHKQLVRDNADLRCELP-KLEKRLRATAERVKALESALK--EAKENAMRDRK-RY 897
E+ V R NA + E+ +L+ R +E +K E N RK +Y
Sbjct: 1106 EKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKY 1165
Query: 898 QQEVDR 903
++ V R
Sbjct: 1166 ERMVSR 1171
Score = 53.1 bits (126), Expect = 1e-06
Identities = 60/235 (25%), Positives = 113/235 (48%), Gaps = 37/235 (15%)
Query: 680 VSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLN 739
+ F+ +++E L +L E K+ L ++ME +++ + +L R++ E+E ++K + ++
Sbjct: 596 LEFERQQREELEKL----ESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQ--- 648
Query: 740 QKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLH 799
LQ+ +++ S IE+ KL+ LL +K E+ R L E ELQ
Sbjct: 649 --LQIRKQEESLKRRSFHIEN-----KLKDLLAEKEKFEEER-----LREQQEIELQKKR 696
Query: 800 NLRKLF--VQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNAD 857
+ F VQ+ R+K EL+N++ A+K +I ++L ++ K+ A
Sbjct: 697 QEEETFLRVQEELQRLK---ELNNNE----KAEKFQI------FQELDQLQKEKDEQYAK 743
Query: 858 LRCELPKLEKRLRATAERVKALESALKEAKENAM---RDRKRYQQEVDRIKEAVR 909
L E +LE++ + V LE L+E +E R ++ +E R E +R
Sbjct: 744 LELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIR 798
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 245 bits (626), Expect = 1e-64
Identities = 251/833 (30%), Positives = 381/833 (45%), Gaps = 118/833 (14%)
Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVI--------GQGKP-------YVF 49
++ +KV R RP+N E+ K + + +G++TV+ G+ KP Y F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 50 DRVLPPNTT----QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
+ NTT QE V+ + I++ +GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIAHDIFDHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK 222
PYV G ++ V+S E++ ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSV 333
VPYRDS +T +L+D+LGGN +T+++ SP+ N ET STL + RAK I N V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAE---EWKKKYEKEKE--------KNKTLKNVIQHLEMELNR----WRNGEAVPE 378
N + A+ E +++ EK +E K LK ++ E + W E + +
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE--EKLRK 416
Query: 379 DEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQ 438
E+I+ + Q+ LE I+ ++GI + + Y +N
Sbjct: 417 TEEIAQERQRQLESM-------GISLEMSGIKVGDDKCYLV--------------NLNAD 455
Query: 439 SQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNY 498
L E L + D + A T +D + + E + A D
Sbjct: 456 PALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASD---------------- 499
Query: 499 DQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL--SNHQKKRATEILNLLLK 556
+ K A + L TT L R L N K++ + L K
Sbjct: 500 --GDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEK 557
Query: 557 DLGEIGGIIGTNDVKTLADVNGVIEEEFTMARL-YISKMKSEVKSLVNRSKQLESAQMDS 615
+ G +D+ ++ + + + A++ I K + + N + LE ++
Sbjct: 558 ETGP-----PEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEE 612
Query: 616 NRKMNAS-----ERELAACQLLISQHEAKIKSLTDYM----QNMEQKRRQLEESQDSL-S 665
R EREL + +S S D + Q +QK Q E +D L
Sbjct: 613 KRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFR 672
Query: 666 EELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEI 725
+ LAKLR E++ + + +E L AEEM K + Q+ A +R R I
Sbjct: 673 QSLAKLR--EQLVKANTLVREANFL-----AEEMSKLTDYQVTLQIPAANLSANRKRGAI 725
Query: 726 EEKQKIIDEIRDLNQKLQL-EQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKR 777
+ I ++R + Q+ EKL + ++ QE + K+ + L KR
Sbjct: 726 VSEPAI--QVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAKRLYGKR 776
Score = 32.7 bits (73), Expect = 1.7
Identities = 116/620 (18%), Positives = 238/620 (38%), Gaps = 128/620 (20%)
Query: 257 KSLSALGNVISALA------EGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFN 310
+SL + GN +A E +++H + + +T+ L D GN + S+ +
Sbjct: 197 ESLMSEGNKSRTVAATNMNEESSRSHAVF-NIIITQTLYDLQSGNSGEKV---SKVSLVD 252
Query: 311 EAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRW 370
A ++ G + +K ++N LT TL VI L +
Sbjct: 253 LAGSERVSKTGAAGERLKEGSNINKSLT----------------TLGLVISSLADQAAGK 296
Query: 371 RNGEAVP-EDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLD 429
+ VP D ++ + NL T +I I+P + Y+E +S+L +
Sbjct: 297 GKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAA--------DNYEETLSTL--RYA 346
Query: 430 DKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQ-IENEAAKDEVKEVL 488
D+ I + + E +++ + R + EK++E+L++ + ++ K++++E
Sbjct: 347 DRAKRIVNHAVVNEDPNAKVIRE------LREEVEKLREQLSQAEAMKAPELKEKLEESE 400
Query: 489 QALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQE-------LSN 541
+ ++EL V + E+K R E++ E ++ ++ + E+S ++ ++
Sbjct: 401 KLIKELTVTW-------EEKLRKTEEIAQERQRQLESMGISL-EMSGIKVGDDKCYLVNL 452
Query: 542 HQKKRATEILNLLLKDLGEIGG-------IIGTNDVKTLADVNGVIEEEFTMARLYISKM 594
+ E+L LKD +G + G +++ + + T+
Sbjct: 453 NADPALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTP------ 506
Query: 595 KSEVKSLVNRSKQLESAQM----------------------------DSNRKMNASEREL 626
K +S VN + + Q+ D ++ E +L
Sbjct: 507 KENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEKETGPPEHDL 566
Query: 627 AACQLLIS---------QHEAKIKSLT--DYMQN---------MEQKRRQLEESQDSLSE 666
A S Q E +K+L D +QN +E+KR LEE +
Sbjct: 567 DAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKRSALEEQRLMYER 626
Query: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIE 726
EL +LR Q+ + Q + L + K + Q E E ++ L++LR+++
Sbjct: 627 ELEQLR-QQLSPDRQPQSSGPDRLAYSSQTAQQK--VTQWAEERDELFRQSLAKLREQLV 683
Query: 727 EKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKG 786
+ ++ E L + E KL+ L+I ++ ++++ Q R K
Sbjct: 684 KANTLVREANFLAE----EMSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGKS 739
Query: 787 LEE-TVSRELQTLHNLRKLF 805
+ T+ + L ++R L+
Sbjct: 740 TQVWTIEKLENKLIDMRDLY 759
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 245 bits (626), Expect = 1e-64
Identities = 251/833 (30%), Positives = 381/833 (45%), Gaps = 118/833 (14%)
Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVI--------GQGKP-------YVF 49
++ +KV R RP+N E+ K + + +G++TV+ G+ KP Y F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 50 DRVLPPNTT----QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
+ NTT QE V+ + I++ +GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIAHDIFDHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK 222
PYV G ++ V+S E++ ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSV 333
VPYRDS +T +L+D+LGGN +T+++ SP+ N ET STL + RAK I N V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAE---EWKKKYEKEKE--------KNKTLKNVIQHLEMELNR----WRNGEAVPE 378
N + A+ E +++ EK +E K LK ++ E + W E + +
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE--EKLRK 416
Query: 379 DEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQ 438
E+I+ + Q+ LE I+ ++GI + + Y +N
Sbjct: 417 TEEIAQERQRQLESM-------GISLEMSGIKVGDDKCYLV--------------NLNAD 455
Query: 439 SQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNY 498
L E L + D + A T +D + + E + A D
Sbjct: 456 PALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASD---------------- 499
Query: 499 DQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL--SNHQKKRATEILNLLLK 556
+ K A + L TT L R L N K++ + L K
Sbjct: 500 --GDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEK 557
Query: 557 DLGEIGGIIGTNDVKTLADVNGVIEEEFTMARL-YISKMKSEVKSLVNRSKQLESAQMDS 615
+ G +D+ ++ + + + A++ I K + + N + LE ++
Sbjct: 558 ETGP-----PEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEE 612
Query: 616 NRKMNAS-----ERELAACQLLISQHEAKIKSLTDYM----QNMEQKRRQLEESQDSL-S 665
R EREL + +S S D + Q +QK Q E +D L
Sbjct: 613 KRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFR 672
Query: 666 EELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEI 725
+ LAKLR E++ + + +E L AEEM K + Q+ A +R R I
Sbjct: 673 QSLAKLR--EQLVKANTLVREANFL-----AEEMSKLTDYQVTLQIPAANLSANRKRGAI 725
Query: 726 EEKQKIIDEIRDLNQKLQL-EQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKR 777
+ I ++R + Q+ EKL + ++ QE + K+ + L KR
Sbjct: 726 VSEPAI--QVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAKRLYGKR 776
Score = 32.7 bits (73), Expect = 1.7
Identities = 116/620 (18%), Positives = 238/620 (38%), Gaps = 128/620 (20%)
Query: 257 KSLSALGNVISALA------EGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFN 310
+SL + GN +A E +++H + + +T+ L D GN + S+ +
Sbjct: 197 ESLMSEGNKSRTVAATNMNEESSRSHAVF-NIIITQTLYDLQSGNSGEKV---SKVSLVD 252
Query: 311 EAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRW 370
A ++ G + +K ++N LT TL VI L +
Sbjct: 253 LAGSERVSKTGAAGERLKEGSNINKSLT----------------TLGLVISSLADQAAGK 296
Query: 371 RNGEAVP-EDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLD 429
+ VP D ++ + NL T +I I+P + Y+E +S+L +
Sbjct: 297 GKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAA--------DNYEETLSTL--RYA 346
Query: 430 DKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQ-IENEAAKDEVKEVL 488
D+ I + + E +++ + R + EK++E+L++ + ++ K++++E
Sbjct: 347 DRAKRIVNHAVVNEDPNAKVIRE------LREEVEKLREQLSQAEAMKAPELKEKLEESE 400
Query: 489 QALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQE-------LSN 541
+ ++EL V + E+K R E++ E ++ ++ + E+S ++ ++
Sbjct: 401 KLIKELTVTW-------EEKLRKTEEIAQERQRQLESMGISL-EMSGIKVGDDKCYLVNL 452
Query: 542 HQKKRATEILNLLLKDLGEIGG-------IIGTNDVKTLADVNGVIEEEFTMARLYISKM 594
+ E+L LKD +G + G +++ + + T+
Sbjct: 453 NADPALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTP------ 506
Query: 595 KSEVKSLVNRSKQLESAQM----------------------------DSNRKMNASEREL 626
K +S VN + + Q+ D ++ E +L
Sbjct: 507 KENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEKETGPPEHDL 566
Query: 627 AACQLLIS---------QHEAKIKSLT--DYMQN---------MEQKRRQLEESQDSLSE 666
A S Q E +K+L D +QN +E+KR LEE +
Sbjct: 567 DAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKRSALEEQRLMYER 626
Query: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIE 726
EL +LR Q+ + Q + L + K + Q E E ++ L++LR+++
Sbjct: 627 ELEQLR-QQLSPDRQPQSSGPDRLAYSSQTAQQK--VTQWAEERDELFRQSLAKLREQLV 683
Query: 727 EKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKG 786
+ ++ E L + E KL+ L+I ++ ++++ Q R K
Sbjct: 684 KANTLVREANFLAE----EMSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGKS 739
Query: 787 LEE-TVSRELQTLHNLRKLF 805
+ T+ + L ++R L+
Sbjct: 740 TQVWTIEKLENKLIDMRDLY 759
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 245 bits (626), Expect = 1e-64
Identities = 251/833 (30%), Positives = 381/833 (45%), Gaps = 118/833 (14%)
Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVI--------GQGKP-------YVF 49
++ +KV R RP+N E+ K + + +G++TV+ G+ KP Y F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 50 DRVLPPNTT----QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
+ NTT QE V+ + I++ +GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIAHDIFDHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK 222
PYV G ++ V+S E++ ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSV 333
VPYRDS +T +L+D+LGGN +T+++ SP+ N ET STL + RAK I N V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAE---EWKKKYEKEKE--------KNKTLKNVIQHLEMELNR----WRNGEAVPE 378
N + A+ E +++ EK +E K LK ++ E + W E + +
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE--EKLRK 416
Query: 379 DEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQ 438
E+I+ + Q+ LE I+ ++GI + + Y +N
Sbjct: 417 TEEIAQERQRQLESM-------GISLEMSGIKVGDDKCYLV--------------NLNAD 455
Query: 439 SQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNY 498
L E L + D + A T +D + + E + A D
Sbjct: 456 PALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASD---------------- 499
Query: 499 DQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL--SNHQKKRATEILNLLLK 556
+ K A + L TT L R L N K++ + L K
Sbjct: 500 --GDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEK 557
Query: 557 DLGEIGGIIGTNDVKTLADVNGVIEEEFTMARL-YISKMKSEVKSLVNRSKQLESAQMDS 615
+ G +D+ ++ + + + A++ I K + + N + LE ++
Sbjct: 558 ETGP-----PEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEE 612
Query: 616 NRKMNAS-----ERELAACQLLISQHEAKIKSLTDYM----QNMEQKRRQLEESQDSL-S 665
R EREL + +S S D + Q +QK Q E +D L
Sbjct: 613 KRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFR 672
Query: 666 EELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEI 725
+ LAKLR E++ + + +E L AEEM K + Q+ A +R R I
Sbjct: 673 QSLAKLR--EQLVKANTLVREANFL-----AEEMSKLTDYQVTLQIPAANLSANRKRGAI 725
Query: 726 EEKQKIIDEIRDLNQKLQL-EQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKR 777
+ I ++R + Q+ EKL + ++ QE + K+ + L KR
Sbjct: 726 VSEPAI--QVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAKRLYGKR 776
Score = 32.7 bits (73), Expect = 1.7
Identities = 116/620 (18%), Positives = 238/620 (38%), Gaps = 128/620 (20%)
Query: 257 KSLSALGNVISALA------EGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFN 310
+SL + GN +A E +++H + + +T+ L D GN + S+ +
Sbjct: 197 ESLMSEGNKSRTVAATNMNEESSRSHAVF-NIIITQTLYDLQSGNSGEKV---SKVSLVD 252
Query: 311 EAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRW 370
A ++ G + +K ++N LT TL VI L +
Sbjct: 253 LAGSERVSKTGAAGERLKEGSNINKSLT----------------TLGLVISSLADQAAGK 296
Query: 371 RNGEAVP-EDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLD 429
+ VP D ++ + NL T +I I+P + Y+E +S+L +
Sbjct: 297 GKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAA--------DNYEETLSTL--RYA 346
Query: 430 DKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQ-IENEAAKDEVKEVL 488
D+ I + + E +++ + R + EK++E+L++ + ++ K++++E
Sbjct: 347 DRAKRIVNHAVVNEDPNAKVIRE------LREEVEKLREQLSQAEAMKAPELKEKLEESE 400
Query: 489 QALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQE-------LSN 541
+ ++EL V + E+K R E++ E ++ ++ + E+S ++ ++
Sbjct: 401 KLIKELTVTW-------EEKLRKTEEIAQERQRQLESMGISL-EMSGIKVGDDKCYLVNL 452
Query: 542 HQKKRATEILNLLLKDLGEIGG-------IIGTNDVKTLADVNGVIEEEFTMARLYISKM 594
+ E+L LKD +G + G +++ + + T+
Sbjct: 453 NADPALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTP------ 506
Query: 595 KSEVKSLVNRSKQLESAQM----------------------------DSNRKMNASEREL 626
K +S VN + + Q+ D ++ E +L
Sbjct: 507 KENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEKETGPPEHDL 566
Query: 627 AACQLLIS---------QHEAKIKSLT--DYMQN---------MEQKRRQLEESQDSLSE 666
A S Q E +K+L D +QN +E+KR LEE +
Sbjct: 567 DAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKRSALEEQRLMYER 626
Query: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIE 726
EL +LR Q+ + Q + L + K + Q E E ++ L++LR+++
Sbjct: 627 ELEQLR-QQLSPDRQPQSSGPDRLAYSSQTAQQK--VTQWAEERDELFRQSLAKLREQLV 683
Query: 727 EKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKG 786
+ ++ E L + E KL+ L+I ++ ++++ Q R K
Sbjct: 684 KANTLVREANFLAE----EMSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGKS 739
Query: 787 LEE-TVSRELQTLHNLRKLF 805
+ T+ + L ++R L+
Sbjct: 740 TQVWTIEKLENKLIDMRDLY 759
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 245 bits (626), Expect = 1e-64
Identities = 251/833 (30%), Positives = 381/833 (45%), Gaps = 118/833 (14%)
Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVI--------GQGKP-------YVF 49
++ +KV R RP+N E+ K + + +G++TV+ G+ KP Y F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 50 DRVLPPNTT----QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
+ NTT QE V+ + I++ +GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIAHDIFDHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK 222
PYV G ++ V+S E++ ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSV 333
VPYRDS +T +L+D+LGGN +T+++ SP+ N ET STL + RAK I N V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAE---EWKKKYEKEKE--------KNKTLKNVIQHLEMELNR----WRNGEAVPE 378
N + A+ E +++ EK +E K LK ++ E + W E + +
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWE--EKLRK 416
Query: 379 DEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQ 438
E+I+ + Q+ LE I+ ++GI + + Y +N
Sbjct: 417 TEEIAQERQRQLESM-------GISLEMSGIKVGDDKCYLV--------------NLNAD 455
Query: 439 SQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNY 498
L E L + D + A T +D + + E + A D
Sbjct: 456 PALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASD---------------- 499
Query: 499 DQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL--SNHQKKRATEILNLLLK 556
+ K A + L TT L R L N K++ + L K
Sbjct: 500 --GDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEK 557
Query: 557 DLGEIGGIIGTNDVKTLADVNGVIEEEFTMARL-YISKMKSEVKSLVNRSKQLESAQMDS 615
+ G +D+ ++ + + + A++ I K + + N + LE ++
Sbjct: 558 ETGP-----PEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEE 612
Query: 616 NRKMNAS-----ERELAACQLLISQHEAKIKSLTDYM----QNMEQKRRQLEESQDSL-S 665
R EREL + +S S D + Q +QK Q E +D L
Sbjct: 613 KRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFR 672
Query: 666 EELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEI 725
+ LAKLR E++ + + +E L AEEM K + Q+ A +R R I
Sbjct: 673 QSLAKLR--EQLVKANTLVREANFL-----AEEMSKLTDYQVTLQIPAANLSANRKRGAI 725
Query: 726 EEKQKIIDEIRDLNQKLQL-EQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKR 777
+ I ++R + Q+ EKL + ++ QE + K+ + L KR
Sbjct: 726 VSEPAI--QVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAKRLYGKR 776
Score = 32.7 bits (73), Expect = 1.7
Identities = 116/620 (18%), Positives = 238/620 (38%), Gaps = 128/620 (20%)
Query: 257 KSLSALGNVISALA------EGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFN 310
+SL + GN +A E +++H + + +T+ L D GN + S+ +
Sbjct: 197 ESLMSEGNKSRTVAATNMNEESSRSHAVF-NIIITQTLYDLQSGNSGEKV---SKVSLVD 252
Query: 311 EAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRW 370
A ++ G + +K ++N LT TL VI L +
Sbjct: 253 LAGSERVSKTGAAGERLKEGSNINKSLT----------------TLGLVISSLADQAAGK 296
Query: 371 RNGEAVP-EDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLD 429
+ VP D ++ + NL T +I I+P + Y+E +S+L +
Sbjct: 297 GKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAA--------DNYEETLSTL--RYA 346
Query: 430 DKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQ-IENEAAKDEVKEVL 488
D+ I + + E +++ + R + EK++E+L++ + ++ K++++E
Sbjct: 347 DRAKRIVNHAVVNEDPNAKVIRE------LREEVEKLREQLSQAEAMKAPELKEKLEESE 400
Query: 489 QALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQE-------LSN 541
+ ++EL V + E+K R E++ E ++ ++ + E+S ++ ++
Sbjct: 401 KLIKELTVTW-------EEKLRKTEEIAQERQRQLESMGISL-EMSGIKVGDDKCYLVNL 452
Query: 542 HQKKRATEILNLLLKDLGEIGG-------IIGTNDVKTLADVNGVIEEEFTMARLYISKM 594
+ E+L LKD +G + G +++ + + T+
Sbjct: 453 NADPALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTP------ 506
Query: 595 KSEVKSLVNRSKQLESAQM----------------------------DSNRKMNASEREL 626
K +S VN + + Q+ D ++ E +L
Sbjct: 507 KENARSCVNGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFEKETGPPEHDL 566
Query: 627 AACQLLIS---------QHEAKIKSLT--DYMQN---------MEQKRRQLEESQDSLSE 666
A S Q E +K+L D +QN +E+KR LEE +
Sbjct: 567 DAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKRSALEEQRLMYER 626
Query: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIE 726
EL +LR Q+ + Q + L + K + Q E E ++ L++LR+++
Sbjct: 627 ELEQLR-QQLSPDRQPQSSGPDRLAYSSQTAQQK--VTQWAEERDELFRQSLAKLREQLV 683
Query: 727 EKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKG 786
+ ++ E L + E KL+ L+I ++ ++++ Q R K
Sbjct: 684 KANTLVREANFLAE----EMSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGKS 739
Query: 787 LEE-TVSRELQTLHNLRKLF 805
+ T+ + L ++R L+
Sbjct: 740 TQVWTIEKLENKLIDMRDLY 759
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 243 bits (619), Expect = 8e-64
Identities = 154/379 (40%), Positives = 221/379 (58%), Gaps = 30/379 (7%)
Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKP------YVFDRVLPPNTT--- 58
S+KV R RP N E + K I + +G+ T +I P + FD +T+
Sbjct: 5 SVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPED 64
Query: 59 -----QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
Q +VYN K+++ EGYN IFAYGQT +GK++TM GK + Q GIIP++
Sbjct: 65 PCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIPQLC 123
Query: 114 HDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLAVHEDKNRVPYVKGCTE 171
++F+ I + +E + + ++VSY EIY +++RDLL+ +K NL V E PYV+ ++
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSK 183
Query: 172 RFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS----GK 227
V+S ++ D++D G R VA TNMNE SSRSH++F I Q+ + E LS K
Sbjct: 184 LAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSK 243
Query: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-----THVPYRDS 282
+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE +K +PYRDS
Sbjct: 244 ISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDS 303
Query: 283 KMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEW 342
+T +L+++LGGN RT +V SP+ N ET STL + RAK IK +N + A
Sbjct: 304 VLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNA--- 360
Query: 343 KKKYEKEKEKNKTLKNVIQ 361
K + KE+ LK++++
Sbjct: 361 -KLVRELKEEVTRLKDLLR 378
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 243 bits (619), Expect = 8e-64
Identities = 154/379 (40%), Positives = 221/379 (58%), Gaps = 30/379 (7%)
Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKP------YVFDRVLPPNTT--- 58
S+KV R RP N E + K I + +G+ T +I P + FD +T+
Sbjct: 5 SVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPED 64
Query: 59 -----QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
Q +VYN K+++ EGYN IFAYGQT +GK++TM GK + Q GIIP++
Sbjct: 65 PCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIPQLC 123
Query: 114 HDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLAVHEDKNRVPYVKGCTE 171
++F+ I + +E + + ++VSY EIY +++RDLL+ +K NL V E PYV+ ++
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSK 183
Query: 172 RFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS----GK 227
V+S ++ D++D G R VA TNMNE SSRSH++F I Q+ + E LS K
Sbjct: 184 LAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSK 243
Query: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-----THVPYRDS 282
+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE +K +PYRDS
Sbjct: 244 ISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDS 303
Query: 283 KMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEW 342
+T +L+++LGGN RT +V SP+ N ET STL + RAK IK +N + A
Sbjct: 304 VLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNA--- 360
Query: 343 KKKYEKEKEKNKTLKNVIQ 361
K + KE+ LK++++
Sbjct: 361 -KLVRELKEEVTRLKDLLR 378
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 238 bits (608), Expect = 2e-62
Identities = 148/361 (40%), Positives = 208/361 (57%), Gaps = 32/361 (8%)
Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKP------YVFDRVLPPNTT 58
A S+KV R RP N E+ R K I + G T ++ +P + FD +T+
Sbjct: 2 AGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTS 61
Query: 59 QEQVYNACAKQIVKDV--------LEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110
E + A KQ+ +D+ EGYN IFAYGQT +GK++TM GK Q GIIP
Sbjct: 62 PEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQ-QGIIP 120
Query: 111 RIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLAVHEDKNRVPYVKG 168
++ D+F I + ++N+ + ++VSY EIY +++RDLL+ +K NL V E PYV+
Sbjct: 121 QLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 180
Query: 169 CTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS--- 225
++ V+S ++ D++D G R VA TNMNE SSRSH++F I Q+ + E ++
Sbjct: 181 LSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEK 240
Query: 226 -GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE----------GTK 274
K+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE K
Sbjct: 241 VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKK 300
Query: 275 T-HVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSV 333
T +PYRDS +T +L+++LGGN RT +V SP+ N ET STL + RAK I+ +
Sbjct: 301 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVI 360
Query: 334 N 334
N
Sbjct: 361 N 361
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 238 bits (607), Expect = 2e-62
Identities = 188/597 (31%), Positives = 292/597 (48%), Gaps = 74/597 (12%)
Query: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQ-------------GKPYVFDRVLP 54
++KV+ R RPL+ E G + I V +GQ K + FD V
Sbjct: 10 ALKVVARCRPLSRKEEAAGHEQILTMD----VKLGQVTLRNPRAAPGELPKTFTFDAVYD 65
Query: 55 PNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAH 114
++ Q +Y+ + ++ VL+G+NGT+FAYGQT +GKT+TM+G +P+L G+IP
Sbjct: 66 ASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFE 125
Query: 115 DIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSK-TNLAVHEDKNRVPYVKGCTERF 173
IF HI S +N ++ ++ SY EIY ++IRDLL L + E+ Y+K +
Sbjct: 126 HIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFV 184
Query: 174 VSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK---LSGKLYL 230
+ +E+ V++ G R V T+MNE SSRSH+IF+I ++ ++ + GKL L
Sbjct: 185 TKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNL 244
Query: 231 VDLAGSEKVSKTG------------------------AEGAVLDEAKNINKSLSALGNVI 266
VDLAGSE+ +K G A G EA IN SLSALGNVI
Sbjct: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304
Query: 267 SALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKT 326
+ALA TH+PYRDSK+TR+LQDSLGGN +T +V P+ + E+ STL F RAK
Sbjct: 305 AALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKN 364
Query: 327 IKNTVSVNLELTAEEWKKKYEKE--KEKNKTLKNVIQHLEMELNRWRNGEAV------PE 378
IKN VN E + +++++E + K + K + R +AV PE
Sbjct: 365 IKNKPRVN-EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPE 423
Query: 379 DEQISA-----KDQKNLEPCDNTPIIDN-IAPVVAGISTEEKEKYDEEISSLYRQLDDKD 432
I A +D N PI+++ + + E+KE+ +EE +++ DD+
Sbjct: 424 GPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQ---DDRS 480
Query: 433 DEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALE 492
++ +L E+ ++ + D +T K + ++L I D E + LE
Sbjct: 481 LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE 540
Query: 493 ELAVNYDQKSQEVEDKTRANEQLTDELA---QKTTTLTTTQRELSQLQELSNHQKKR 546
K QE+ ++ R ++ E+ ++T L T L Q E+ + K+
Sbjct: 541 -------LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKK 590
Score = 52.8 bits (125), Expect = 2e-06
Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 32/191 (16%)
Query: 641 KSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMK 700
K++ +Y+Q EQK R LEE + ++ ++ + L ++EK + ++K E L R Q A E+
Sbjct: 455 KNMENYLQ--EQKER-LEEEKAAIQDDRS-LVSEEKQKLLEEKEKMLEDLRREQQATELL 510
Query: 701 KALEQQMES-----------HREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQE-- 747
A + MES H QK L R EI E+++ R++ Q++ L E
Sbjct: 511 AAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKR---REREMQQEMMLRDEET 567
Query: 748 -KLSSDYNKLKIEDQEREMKLEKLLL-----------LNDKREQAREDLKGLEETVSREL 795
+L Y L+ E + + KL+KL +D+ + R+DL+ + +REL
Sbjct: 568 MELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTREL 627
Query: 796 QTLHNLRKLFV 806
+ + + + F+
Sbjct: 628 KLKYLIIENFI 638
Score = 38.9 bits (89), Expect = 0.023
Identities = 62/297 (20%), Positives = 123/297 (41%), Gaps = 77/297 (25%)
Query: 648 QNMEQKRRQLEESQDSL----SEELAKLRAQ-EKMHEVSFQDKEKEH------------- 689
+N++ K R E+ +D+L EE+A+L+AQ EK + + + K
Sbjct: 363 KNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYP 422
Query: 690 ---LTRLQDAEE--------------MKKALEQQMESHREAHQKQLSRLRDEIEEKQKII 732
+ AEE ++ ALE+ ME++ + +++L + I++ + ++
Sbjct: 423 EGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLV 482
Query: 733 DEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVS 792
E + QKL E+EK+ +ED RE + +LL K +++ + G
Sbjct: 483 SEEK---QKLLEEKEKM--------LEDLRREQQATELLAAKYKAMESKLLIGGRN---- 527
Query: 793 RELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLV 852
+ D T +K +EL + A QK++ E ++Q + ++
Sbjct: 528 -------------IMDHTNEQQKMLELKRQE---IAEQKRR----EREMQQ-----EMML 562
Query: 853 RD--NADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEA 907
RD +LR L++ + +++K L + L+ K Y + ++EA
Sbjct: 563 RDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEA 619
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 230 bits (587), Expect = 4e-60
Identities = 144/367 (39%), Positives = 212/367 (57%), Gaps = 32/367 (8%)
Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFK-GDETVVIGQGKPYVFDRVLPPNTTQEQVYN 64
E ++V R RPL E+L G + + + G V +G+ + + F VL + QE VY
Sbjct: 13 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQ 72
Query: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTM-----EGKLHDPQLMGIIPRIAHDIFDH 119
AC + +++ EG+N T+FAYGQT SGKT+TM L D Q GI+PR + F
Sbjct: 73 ACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQ--GIVPRAMAEAFKL 130
Query: 120 IYSMDEN--LEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNRVPYVKGCTERFVS 175
I DEN L+ + VSY E+Y ++ RDLL+V + ++ + ED+ + G E V
Sbjct: 131 I---DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
Query: 176 SPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK--------LSGK 227
+EV+ +++ G A RH T++N SSRSH++F + ++Q + L K
Sbjct: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
Query: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--THVPYRDSKMT 285
+ VDLAGSE+V KTG+ G L E+ IN SL ALGNVISAL + + +H+PYRDSK+T
Sbjct: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
Query: 286 RILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKK 345
RIL+DSLGGN +T ++ C SPS + ET +TL + RA+ I+N +VN W+ +
Sbjct: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN-------WRPE 360
Query: 346 YEKEKEK 352
E+ E+
Sbjct: 361 AERPPEE 367
Score = 47.8 bits (112), Expect = 5e-05
Identities = 59/297 (19%), Positives = 132/297 (44%), Gaps = 38/297 (12%)
Query: 628 ACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSE----------ELAKLR----- 672
A Q L QH +I+ L Q EQ R +L E Q L E E ++L+
Sbjct: 733 AAQALNRQHSQRIRELE---QEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRR 789
Query: 673 ---AQEKMHEVSFQDKEKEHLTRLQ-DAEEMKKALEQQMESHREAHQKQLSRLRDEIEEK 728
AQ ++ + + + E L L +E+ + LE+ ++ R+ + RLR+E E+K
Sbjct: 790 VAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQK 849
Query: 729 QKIIDE-------IRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAR 781
+++ E +++L K + +Q+ L ++ ++R ++ +++++
Sbjct: 850 RRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIE 909
Query: 782 EDLKGLEETVSRELQTLHNLRKLFVQDLTTR----VKKSVELDNDDGGGSAAQKQKISFL 837
E K L++ + + LQ L +L ++L R KK + G + +++
Sbjct: 910 EQKKWLDQEMEKVLQQRRALEEL-GEELHKREAILAKKEALMQEKTG----LESKRLRSS 964
Query: 838 ENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDR 894
+ E + +V +L +L + +L + + ++++ +L++ K++ ++ R
Sbjct: 965 QALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQR 1021
Score = 41.6 bits (96), Expect = 0.004
Identities = 82/451 (18%), Positives = 183/451 (40%), Gaps = 70/451 (15%)
Query: 412 EEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELT 471
E KE D S ++ + Q Q+ ++ KQ L A + + ++++ +
Sbjct: 770 EGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQ 829
Query: 472 RLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQR 531
++ + + ++E + L ++ V++ +EQ L KT + QR
Sbjct: 830 LMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQR 889
Query: 532 E-----------LSQLQELSNHQKKRATEILNLL--LKDLGEIGGIIGTNDVKTLADVNG 578
+ L Q Q++ +K E+ +L + L E+G + + LA
Sbjct: 890 KRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREA-ILAKKEA 948
Query: 579 VIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQ-------- 630
+++E+ + + ++ + +V S +LE + + + K + A Q
Sbjct: 949 LMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEID 1008
Query: 631 --------LLISQHEAKIKSLTDYMQNMEQKRR--QLEESQDSLSEEL------------ 668
LL + E K + + E++R QL+E+ ++L +
Sbjct: 1009 SLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQR 1068
Query: 669 -----AKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQL--SRL 721
A L +Q +M+ ++ + +L+ + + K ++ + E HQ+Q+ S L
Sbjct: 1069 VLRASASLLSQCEMNLMA----KLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSEL 1124
Query: 722 RDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLL--------- 772
++EE+Q+++ + ++ LE+++L D +L ++ +E E ++ LL
Sbjct: 1125 EMQLEEQQRLVYWL-----EVALERQRLEMD-RQLTLQQKEHEQNMQLLLQQSRDHLGEG 1178
Query: 773 LNDKREQAREDLKGLEETVSRELQTLHNLRK 803
L D R Q ++ LE+ + R + L++
Sbjct: 1179 LADSRRQYEARIQALEKELGRYMWINQELKQ 1209
Score = 33.5 bits (75), Expect = 0.98
Identities = 44/196 (22%), Positives = 89/196 (45%), Gaps = 19/196 (9%)
Query: 734 EIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDL----KGLEE 789
+IR+L +++++E + K +++ L + EQ R +L + L E
Sbjct: 709 KIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRE 768
Query: 790 TVSRELQTLHNLRKLFVQDLTTRV---KKSVELDNDDGGGSAAQKQKISFLENNLEQLTK 846
+ELQ +L Q+ RV + V++ + +KQ L + Q K
Sbjct: 769 LEGKELQDAGERSRL--QEFRRRVAAAQSQVQVLKE-------KKQATERLVSLSAQSEK 819
Query: 847 VHKQLVRDNADLRCELPKLEKRLRATAERVKALESAL--KEAKENAMRDRKRYQQEVDRI 904
++L R+ +R + +L++RLR E+ + LE+ + ++ + + + QQ++ +I
Sbjct: 820 RLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKI 879
Query: 905 K-EAVRAKNMARRAHS 919
K E + A RR+ S
Sbjct: 880 KTEEIAAFQRKRRSGS 895
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 228 bits (582), Expect = 2e-59
Identities = 161/433 (37%), Positives = 228/433 (52%), Gaps = 52/433 (12%)
Query: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVI------------GQGKPYVFDR-- 51
+ +KV R RP+N E K + ++ ++ GQ K + +D
Sbjct: 3 DSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCF 62
Query: 52 ------VLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
V Q+ V+ + I+++ +GYN IFAYGQT SGK++TM G P
Sbjct: 63 WSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP-- 120
Query: 106 MGIIPRIAHDIFDHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNR 162
G+IPR+ +F+ + E F ++VSY EIY +K+RDLLD S+ L V E
Sbjct: 121 -GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVL 179
Query: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK 222
PYV G ++ V+S +++ ++ EG +R VA TNMNE SSRSH++F I + + +
Sbjct: 180 GPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKS 239
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG KL LVDLAGSE+ +KTGA G L E NINKSL+ LG VISALA+
Sbjct: 240 GTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNK 299
Query: 274 KTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSV 333
VPYRDS +T +L+DSLGGN +T +V SP+ N ET STL + RAK I N V
Sbjct: 300 NKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVV 359
Query: 334 NLELTA-------EEWKKKYEK----EKEKNKTLKNVIQHLEMELNR----WRNGEAVPE 378
N + A EE +K E+ E K+ LK+ ++ E + W E + +
Sbjct: 360 NEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWE--EKLRK 417
Query: 379 DEQISAKDQKNLE 391
E+I+ + QK LE
Sbjct: 418 TEEIAQERQKQLE 430
Score = 30.8 bits (68), Expect = 6.3
Identities = 26/110 (23%), Positives = 53/110 (48%), Gaps = 13/110 (11%)
Query: 662 DSLSEELAKLR-AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSR 720
D+ E L+ LR A H V+ ++ R+ ++++ +E+ E +A +
Sbjct: 335 DNYDETLSTLRYADRAKHIVNHAVVNEDPNARI--IRDLREEVEKLREQLTKAEAMKSPE 392
Query: 721 LRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKL 770
L+D +EE +K+I E+ ++ + E+++ QER+ +LE L
Sbjct: 393 LKDRLEESEKLIQEMTVTWEEKLRKTEEIA----------QERQKQLESL 432
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 222 bits (565), Expect = 1e-57
Identities = 160/508 (31%), Positives = 256/508 (50%), Gaps = 58/508 (11%)
Query: 5 AECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQG------KPYVFDRVL----- 53
A S+KV R RP N E + K + +G+ T +I K + FD
Sbjct: 2 AGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTS 61
Query: 54 ---PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110
P +Q+QVY ++++ EGYN IFAYGQT +GK++TM G+ +P GI+P
Sbjct: 62 TEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGR-QEPGQQGIVP 120
Query: 111 RIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLAVHEDKNRVPYVKG 168
++ D+F + + L + ++VSY EIY +++RDLL+ S+ +L V E PYV+
Sbjct: 121 QLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQD 180
Query: 169 CTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQE------NVETEK 222
++ V+S ++ D++D G R VA TNMNE SSRSH++F I Q +++EK
Sbjct: 181 LSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEK 240
Query: 223 KLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GTKTHV 277
K+ LVDLAGSE+ +GA G L E NINKSL+ LG VISALA+ +
Sbjct: 241 V--SKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFI 298
Query: 278 PYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLEL 337
PYRDS +T +L+++LGGN RT ++ SP+ N ET STL + R K I+ +N +
Sbjct: 299 PYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDP 358
Query: 338 TAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTP 397
A +I+ L+ E+ R R + + SA + E
Sbjct: 359 NA------------------RLIRELQEEVARLRE-LLMAQGLSASALEGLKTEEGSVRG 399
Query: 398 IIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLA-EKLKQQMLDQDELL 456
+ ++ A +S ++ E+ + N +SQ+ E+ +++ + ++++
Sbjct: 400 ALPAVSSPPAPVSPSSPTTHNGELEPSFSP--------NTESQIGPEEAMERLQETEKII 451
Query: 457 ASTRRDYEKIQEELTRLQIENEAAKDEV 484
A +E+ + L++E EA E+
Sbjct: 452 AELNETWEEKLRKTEALRMEREALLAEM 479
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 221 bits (564), Expect = 2e-57
Identities = 195/591 (32%), Positives = 284/591 (48%), Gaps = 63/591 (10%)
Query: 9 IKVMCRFRPLNEAEILRG--------DKFI----PK------FKGDET----VVIGQGKP 46
+KV+ R RP N E G DK I PK F G +T V+ Q K
Sbjct: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
Query: 47 --YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104
+VFD V +TQ +V+ K I++ L GYN T+ AYG T +GKTHTM G +P
Sbjct: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
Query: 105 LMGIIPRIAHDIFDHIYS-MDENLEFHI---KVSYFEIYLDKIRDLLDVSKTNLAVHEDK 160
+M + H+Y MDE E I VSY E+Y ++IRDLL V+ LAV ED
Sbjct: 132 VMYLTML-------HLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDT 183
Query: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 220
+ V G T S EE++ ++D G NR T+MN SSRSH++F I ++Q++
Sbjct: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
Query: 221 EKKLS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKT-- 275
+ K+ L+DLAGSE+ S +GA+G E NIN+SL ALGNVI+ALA+ +
Sbjct: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
Query: 276 HVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIK-----NT 330
H+PYR+SK+TR+L+DSLGGNC+T ++ SPS +T +TL + RAK IK N
Sbjct: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
Query: 331 VSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNL 390
++VN +T ++ K ++K + LK ++ E E + N E IS +K +
Sbjct: 364 LNVNNHIT--QYVKICNEQKAEILLLKEKLKAYE-EQKAFTN-ENDQAKLMISNPQEKEI 419
Query: 391 EPCDN--TPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQ 448
E + N + E + E+ S Y+Q K E+ EK +
Sbjct: 420 ERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGK 479
Query: 449 MLDQDELLASTRRDY-EKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVED 507
D + TRR Y EK +EE + EN V++ + L + + +++
Sbjct: 480 R-DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLH- 537
Query: 508 KTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDL 558
L + L R + L L Q ++ +LN LL L
Sbjct: 538 --------CHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTL 580
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 219 bits (558), Expect = 1e-56
Identities = 131/353 (37%), Positives = 199/353 (56%), Gaps = 24/353 (6%)
Query: 3 DPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVI---------------GQGKPY 47
D + + V R RP++ AE+ G I ++ VV+ + K Y
Sbjct: 6 DSKDQQLMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSY 65
Query: 48 VFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMG 107
+FD TQE VY A K +++ V+ GYN T+FAYG T GKT+TM G +P G
Sbjct: 66 LFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEP---G 122
Query: 108 IIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVK 167
I + +D+F I ++E+ + +SY EIY + IRDLL+ S L + ED V V
Sbjct: 123 IYVQTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVA 182
Query: 168 GCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ----ENVETEKK 223
G TE + +E+M ++ +G R T N+ SSRSH++ + ++Q +N+ E +
Sbjct: 183 GITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVR 242
Query: 224 LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-GTKTHVPYRDS 282
G+L+++DLAGSE+ S+T G + E +IN+SL ALGN I+AL++ G+ ++ YRDS
Sbjct: 243 -QGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDS 301
Query: 283 KMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNL 335
K+TR+L+DSLGGN RT ++ SP+ E+++TL + RAK IK V NL
Sbjct: 302 KLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNL 354
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 218 bits (555), Expect = 2e-56
Identities = 123/299 (41%), Positives = 185/299 (61%), Gaps = 9/299 (3%)
Query: 42 GQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH 101
G+ +VFDRV TQ+ V+ ++ L+GYN ++FAYG T +GKTHTM G+
Sbjct: 65 GKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGREG 124
Query: 102 DPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKN 161
DP GI+ +++ + + + F + +SY E+Y ++I DLL+ K LA+ ED +
Sbjct: 125 DP---GIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLE-PKGPLAIREDPD 180
Query: 162 RVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVE-- 219
+ V+G + +S E++++++ G NR T+ N SSRSH+IF I +KQ++
Sbjct: 181 KGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPG 240
Query: 220 -TEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE--GTKTH 276
T+ K+ L+DLAGSE+ S T A+G L E NIN+SL AL NV++ALA+ G KTH
Sbjct: 241 LTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKTH 300
Query: 277 VPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNL 335
VPYRDSK+TR+L+DSLGGNCRT ++ SPS +T +TL + RAK I+ ++ N+
Sbjct: 301 VPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLSLKSNV 359
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,146,309
Number of Sequences: 37866
Number of extensions: 1461935
Number of successful extensions: 24753
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 636
Number of HSP's successfully gapped in prelim test: 1253
Number of HSP's that attempted gapping in prelim test: 7594
Number of HSP's gapped (non-prelim): 7522
length of query: 957
length of database: 18,247,518
effective HSP length: 112
effective length of query: 845
effective length of database: 14,006,526
effective search space: 11835514470
effective search space used: 11835514470
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.