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Search of human proteins with 4758646
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758646 kinesin family member 3B [Homo sapiens]
(747 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758646 kinesin family member 3B [Homo sapiens] 1458 0.0
gi|41352705 kinesin family member 3C [Homo sapiens] 907 0.0
gi|46852174 kinesin family member 3A [Homo sapiens] 668 0.0
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 455 e-128
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 455 e-128
gi|13699824 kinesin family member 11 [Homo sapiens] 320 3e-87
gi|46852172 kinesin family member 13B [Homo sapiens] 300 2e-81
gi|9910266 kinesin family member 15 [Homo sapiens] 300 3e-81
gi|40254834 kinesin family member 1C [Homo sapiens] 298 9e-81
gi|45446749 kinesin family member 5A [Homo sapiens] 296 4e-80
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 290 4e-78
gi|71061468 centromere protein E [Homo sapiens] 288 1e-77
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 287 2e-77
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 287 2e-77
gi|30794488 kinesin family member 27 [Homo sapiens] 287 2e-77
gi|4758650 kinesin family member 5C [Homo sapiens] 286 5e-77
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 283 3e-76
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 283 3e-76
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 283 3e-76
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 283 3e-76
gi|116686122 kinesin family member 4 [Homo sapiens] 283 3e-76
gi|4758648 kinesin family member 5B [Homo sapiens] 282 7e-76
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 282 9e-76
gi|150010604 kinesin family member 4B [Homo sapiens] 281 1e-75
gi|38569484 kinesin family member 21A [Homo sapiens] 269 6e-72
gi|7661878 kinesin family member 14 [Homo sapiens] 268 1e-71
gi|148612831 kinesin family member 18A [Homo sapiens] 264 3e-70
gi|83716024 kinesin family member 21B [Homo sapiens] 262 1e-69
gi|203096856 kinesin family member 7 [Homo sapiens] 254 2e-67
gi|122937289 kinesin family member 18B [Homo sapiens] 249 9e-66
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 1458 bits (3774), Expect = 0.0
Identities = 747/747 (100%), Positives = 747/747 (100%)
Query: 1 MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFD 60
MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFD
Sbjct: 1 MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFD 60
Query: 61 AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP 120
AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP
Sbjct: 61 AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP 120
Query: 121 NSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLS 180
NSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLS
Sbjct: 121 NSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLS 180
Query: 181 SFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGK 240
SFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGK
Sbjct: 181 SFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGK 240
Query: 241 LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRL 300
LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRL
Sbjct: 241 LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRL 300
Query: 301 LQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQE 360
LQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQE
Sbjct: 301 LQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQE 360
Query: 361 EIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEK 420
EIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEK
Sbjct: 361 EIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEK 420
Query: 421 LEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKN 480
LEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKN
Sbjct: 421 LEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKN 480
Query: 481 IVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKK 540
IVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKK
Sbjct: 481 IVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKK 540
Query: 541 LKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIM 600
LKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIM
Sbjct: 541 LKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIM 600
Query: 601 NRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENI 660
NRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENI
Sbjct: 601 NRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENI 660
Query: 661 VLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSG 720
VLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSG
Sbjct: 661 VLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSG 720
Query: 721 RKSGSSSSSSGTPASQLYPQSRGLVPK 747
RKSGSSSSSSGTPASQLYPQSRGLVPK
Sbjct: 721 RKSGSSSSSSGTPASQLYPQSRGLVPK 747
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 907 bits (2344), Expect = 0.0
Identities = 476/714 (66%), Positives = 574/714 (80%), Gaps = 48/714 (6%)
Query: 2 SKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDA 61
SK K+SE+++VV RCRP++ KE+AA +++++ +DVKLGQV+++NP+ E+PKTFTFDA
Sbjct: 3 SKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDA 62
Query: 62 VYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPN 121
VYD ++KQ +LYDET RPL+DSVLQGFNGT+FAYGQTGTGKTYTM+G +PE RGVIPN
Sbjct: 63 VYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPN 122
Query: 122 SFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSS 181
+F+HIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSK+ KRLELKE P+TGVY+KDLSS
Sbjct: 123 AFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSS 182
Query: 182 FVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKL 241
FVTK+VKEIEHVMN+GNQ R+VG+T+MNE SSRSHAIF+IT+ECSE G DG++HIRVGKL
Sbjct: 183 FVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKL 242
Query: 242 NLVDLAGSERQAKT------------------------GAQGERLKEATKINLSLSALGN 277
NLVDLAGSERQ K GA GER KEA+KINLSLSALGN
Sbjct: 243 NLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGN 302
Query: 278 VISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRA 337
VI+AL +STHIPYRDSKLTRLLQDSLGGNAKT+MVA +GPAS++ +E+L+TLR+ANRA
Sbjct: 303 VIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRA 362
Query: 338 KNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRS-IGRRKRRE-KRREGGGSGGGGEE 395
KNIKNKPRVNEDPKD LLREFQEEIARLKAQLEKR +G+R RR+ RR+ S G
Sbjct: 363 KNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYP 422
Query: 396 EEE--EGEEGEEEGDDK------------------DDYWREQQEKLEIEKRAIVEDHSLV 435
E E EEE D+ ++Y +EQ+E+LE EK AI +D SLV
Sbjct: 423 EGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLV 482
Query: 436 AEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQK 495
+EEK +LL+EKEK +EDLRRE+ A E+L AK KAMESKLL+GG+NI+DHTNEQQK+LE K
Sbjct: 483 SEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELK 542
Query: 496 RQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEI 555
RQEIAEQKRRERE+QQ+M RDEET+EL+ TY+SLQQEV++KTKKLKKL++KLQAVKAEI
Sbjct: 543 RQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEI 602
Query: 556 HDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLH 615
D +E+I+ RQ+LE+ QNE TRELKLK+LIIENFIP EEK+KIMNR F D EE+ WK
Sbjct: 603 QDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQ 662
Query: 616 PI--TRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLELDM 667
P+ + + QM KRP SAVGYKRP+SQ+AR++M + RYRAENI+ LELD+
Sbjct: 663 PLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDV 716
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 668 bits (1724), Expect = 0.0
Identities = 351/706 (49%), Positives = 493/706 (69%), Gaps = 29/706 (4%)
Query: 3 KLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAV 62
K +S ++V+VVVRCRP+N +EK+ Y + V VD G ++V + +++E PKTFTFD V
Sbjct: 8 KPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITV-HKTDSSNEPPKTFTFDTV 66
Query: 63 YDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNS 122
+ +KQ ++Y+ T RP++DSVL+G+NGTIFAYGQTGTGKT+TMEG+R PE RG+IPNS
Sbjct: 67 FGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNS 126
Query: 123 FDHIFTHISRSQNQ-QYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSS 181
F HIF HI++++ ++LVR SYLEIY EE+RDLL KDQT+RLE+KERPD GVY+KDLS+
Sbjct: 127 FAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSA 186
Query: 182 FVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKL 241
+V + +++ +M +G++NRSVGATNMNEHSSRSHAIF ITIECSE G+DG H+R+GKL
Sbjct: 187 YVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKL 246
Query: 242 NLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLL 301
+LVDLAGSERQAKTGA G+RLKEATKINLSLS LGNVISALVDGKSTH+PYR+SKLTRLL
Sbjct: 247 HLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLL 306
Query: 302 QDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEE 361
QDSLGGN+KT+M AN+GPA YN +ET++TLRYANRAKNIKNK R+NEDPKDALLR+FQ+E
Sbjct: 307 QDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKE 366
Query: 362 IARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDK---------DD 412
I LK +LE+ + G G E+++EEGE GE+ K D
Sbjct: 367 IEELKKKLEE---------GEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPD 417
Query: 413 YWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMES 472
E Q K++ E++A+ + EE+ + E EK+ +DL + + + L K+ A+E
Sbjct: 418 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 477
Query: 473 KLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
K++VGG +++ EQ+K+LE+ E+ E+++R ++++++E +++E L+++E Y+SLQ+
Sbjct: 478 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE 537
Query: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIP 592
E KTKKLKK+++ L A K+E+ DLQ+EH +E + L + +L+REL+L+ LII+NFIP
Sbjct: 538 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP 597
Query: 593 LEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPE 652
+ + I N ++E+ W+L + N + PV K P + E
Sbjct: 598 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE 657
Query: 653 ARYRAENIVLLELDMPSRTTRDYEGPAI-----APKVQAALDAALQ 693
R L++L+ P RT++ P + K + +D+ LQ
Sbjct: 658 ESLRQS---LMKLERP-RTSKGKARPKTGRRKRSAKPETVIDSLLQ 699
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 455 bits (1171), Expect = e-128
Identities = 247/472 (52%), Positives = 325/472 (68%), Gaps = 9/472 (1%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDW 65
+SE+V+VVVRCRPMN +E+ VV VD Q ++NP G A E PK FTFD Y
Sbjct: 2 ASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNP-GAADEPPKQFTFDGAYHV 60
Query: 66 NAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDH 125
+ ++Y+E PLV+ V +G+NGTIFAYGQTG+GK++TM+G+ P +RG+IP +F+H
Sbjct: 61 DHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEH 120
Query: 126 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTK 185
+F + ++N ++LVRASYLEIY E++RDLL D ++LELKE P+ GVYVK LS
Sbjct: 121 VFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 186 SVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVD 245
SV + EH+M G +NRSVG T MN+ SSRSH+IF I+IE S V G++H+R GKLNLVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 246 LAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSL 305
LAGSERQ+KTGA GERLKEATKINLSLSALGNVISALVDG+ H+PYRDSKLTRLLQDSL
Sbjct: 241 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSL 300
Query: 306 GGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARL 365
GGN KT+MVA + PA N +ETL+TLRYANRAKNI+NKPR+NEDPKDALLRE+QEEI +L
Sbjct: 301 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKL 360
Query: 366 KAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQE----KL 421
KA L ++ R+ EE+ + + + + RE+ E +L
Sbjct: 361 KAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQLIREEYEERLARL 420
Query: 422 EIEKRAIVEDHSLVAEEKMRLLKEKEKKM----EDLRREKDAAEMLGAKIKA 469
+ + +A E + + E+ + + ++ E+LR+E +A +G KA
Sbjct: 421 KADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKA 472
Score = 68.6 bits (166), Expect = 2e-11
Identities = 57/212 (26%), Positives = 98/212 (46%), Gaps = 23/212 (10%)
Query: 465 AKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELK 524
A+++ +E ++ VGG+ N+ K ++R+ A+++R++ Q D L
Sbjct: 743 ARLQLLEQQV-VGGEQA---KNKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLL 798
Query: 525 ETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKH 584
Y S+Q+EV K+K L+K+ KL+A + EI DLQ E E+ + T R+ L
Sbjct: 799 NVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQ 858
Query: 585 LIIENFIPLEEK-------SKIMNRAFFDEEEDHWKL-HPITRLEN--------QQMMKR 628
++E PL + KI+ + +DE+ WK+ HP+ + Q R
Sbjct: 859 QLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKIPHPVITKTSLPVVSTGPQNKPAR 918
Query: 629 PVSAVGYKRPLSQHARMSMMIRPEARYRAENI 660
SA P + R +M+ +R +ENI
Sbjct: 919 KTSAADNGEPNMEDDRYRLML---SRSNSENI 947
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 455 bits (1171), Expect = e-128
Identities = 247/472 (52%), Positives = 325/472 (68%), Gaps = 9/472 (1%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDW 65
+SE+V+VVVRCRPMN +E+ VV VD Q ++NP G A E PK FTFD Y
Sbjct: 2 ASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNP-GAADEPPKQFTFDGAYHV 60
Query: 66 NAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDH 125
+ ++Y+E PLV+ V +G+NGTIFAYGQTG+GK++TM+G+ P +RG+IP +F+H
Sbjct: 61 DHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEH 120
Query: 126 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTK 185
+F + ++N ++LVRASYLEIY E++RDLL D ++LELKE P+ GVYVK LS
Sbjct: 121 VFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 186 SVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVD 245
SV + EH+M G +NRSVG T MN+ SSRSH+IF I+IE S V G++H+R GKLNLVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 246 LAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSL 305
LAGSERQ+KTGA GERLKEATKINLSLSALGNVISALVDG+ H+PYRDSKLTRLLQDSL
Sbjct: 241 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSL 300
Query: 306 GGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARL 365
GGN KT+MVA + PA N +ETL+TLRYANRAKNI+NKPR+NEDPKDALLRE+QEEI +L
Sbjct: 301 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKL 360
Query: 366 KAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQE----KL 421
KA L ++ R+ EE+ + + + + RE+ E +L
Sbjct: 361 KAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQLIREEYEERLARL 420
Query: 422 EIEKRAIVEDHSLVAEEKMRLLKEKEKKM----EDLRREKDAAEMLGAKIKA 469
+ + +A E + + E+ + + ++ E+LR+E +A +G KA
Sbjct: 421 KADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKA 472
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/213 (26%), Positives = 98/213 (46%), Gaps = 24/213 (11%)
Query: 465 AKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELK 524
A+++ +E ++ VGG+ N+ K ++R+ A+++R++ Q D L
Sbjct: 743 ARLQLLEQQV-VGGEQA---KNKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLL 798
Query: 525 ETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKH 584
Y S+Q+EV K+K L+K+ KL+A + EI DLQ E E+ + T R+ L
Sbjct: 799 NVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQ 858
Query: 585 LIIENFIPLEEK-------SKIMNRAFFDEEEDHWKL-HPITRLEN---------QQMMK 627
++E PL + KI+ + +DE+ WK+ HP+ + Q
Sbjct: 859 QLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKIPHPVITKTSLPVAVSTGPQNKPA 918
Query: 628 RPVSAVGYKRPLSQHARMSMMIRPEARYRAENI 660
R SA P + R +M+ +R +ENI
Sbjct: 919 RKTSAADNGEPNMEDDRYRLML---SRSNSENI 948
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 320 bits (820), Expect = 3e-87
Identities = 215/593 (36%), Positives = 319/593 (53%), Gaps = 69/593 (11%)
Query: 3 KLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAV 62
K + ++++VVVRCRP N E+ AS +V+ D +VSV+ KT+TFD V
Sbjct: 12 KEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMV 71
Query: 63 YDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEK------- 115
+ + KQ ++Y P++D V+ G+N TIFAYGQTGTGKT+TMEG R E+
Sbjct: 72 FGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP 131
Query: 116 -RGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLL--SKDQTKRLELKERPDT 172
G+IP + IF ++ ++ V+ S LEIY EE+ DLL S D ++RL++ + P
Sbjct: 132 LAGIIPRTLHQIFEKLT-DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRN 190
Query: 173 --GVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGL 230
GV +K L + E+ ++ G R+ AT MN +SSRSH++F +TI E +
Sbjct: 191 KRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTI 250
Query: 231 DGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHI 290
DGE +++GKLNLVDLAGSE ++GA +R +EA IN SL LG VI+ALV+ ++ H+
Sbjct: 251 DGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE-RTPHV 309
Query: 291 PYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNED- 349
PYR+SKLTR+LQDSLGG +T ++A + PAS N+EETL+TL YA+RAKNI NKP VN+
Sbjct: 310 PYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKL 369
Query: 350 PKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDD 409
K AL++E+ EEI RLK L E+ G EE
Sbjct: 370 TKKALIKEYTEEIERLKRDL-----------------------AAAREKNGVYISEEN-- 404
Query: 410 KDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKA 469
+R KL +++ IVE EK+ ++E+ ++ +L +
Sbjct: 405 ----FRVMSGKLTVQEEQIVE-----LIEKIGAVEEELNRVTELFMD------------- 442
Query: 470 MESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSS 529
L K+ + + ++ + ++ QE Q +E I +ES +E +L + S
Sbjct: 443 -NKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEE---KLHDAASK 498
Query: 530 LQQEVDIKTKKLKKLFSKLQAVKA-EIHDLQEEHI--KERQELEQTQNELTRE 579
L V+ TK + L SKL KA + H+ + + I K L EL ++
Sbjct: 499 LLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKD 551
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 300 bits (769), Expect = 2e-81
Identities = 194/440 (44%), Positives = 263/440 (59%), Gaps = 42/440 (9%)
Query: 10 VRVVVRCRPMNGKEKAASYDKVVDVD---VKLGQVSVKNPKGTAHEMPKTFTFDAVYDWN 66
V+V VR RPMN +E VVDVD V L V+ KG A PK F +D + W+
Sbjct: 6 VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCF-WS 64
Query: 67 A-----KQFELYDETFRPLVDSVLQ----GFNGTIFAYGQTGTGKTYTMEGIRGDPEKRG 117
+++ D F+ L +++LQ G+N IFAYGQTG+GK+YTM G P G
Sbjct: 65 MDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP---G 121
Query: 118 VIPNSFDHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLS-KDQTKRLELKERPDTGV 174
+IP +F + +N Q + V SY+EIY E++RDLL K + L+++E G
Sbjct: 122 LIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGP 181
Query: 175 YVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECS----EVGL 230
YV LS S K+IE +M+ GN++R+V ATNMNE SSRSHA+F IT+ + + G
Sbjct: 182 YVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGT 241
Query: 231 DGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD-----G 285
GE +VGKL+LVDLAGSER KTGA G+RLKE + IN SL+ LG VISAL D
Sbjct: 242 SGE---KVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKN 298
Query: 286 KSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPR 345
K+ +PYRDS LT LL+DSLGGN+KT MVA V PA+ N +ETL+TLRYA+RAK+I N
Sbjct: 299 KNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAV 358
Query: 346 VNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEE---EEEGEE 402
VNEDP ++R+ +EE+ +L+ QL K + + R E E E +E
Sbjct: 359 VNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLE--------ESEKLIQEMTVT 410
Query: 403 GEEEGDDKDDYWREQQEKLE 422
EE+ ++ +E+Q++LE
Sbjct: 411 WEEKLRKTEEIAQERQKQLE 430
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 300 bits (768), Expect = 3e-81
Identities = 229/620 (36%), Positives = 337/620 (54%), Gaps = 73/620 (11%)
Query: 8 ESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVK---NPKGTAHEMPKTFTFDAVYD 64
++++V VR RP + +A ++ + + V L S++ NP+ PKTFTFD V D
Sbjct: 25 DAIKVFVRIRPPAERSGSADGEQNLCLSV-LSSTSLRLHSNPE------PKTFTFDHVAD 77
Query: 65 WNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPE----KRGVIP 120
+ Q ++ + +V+S + G+NGTIFAYGQTG+GKT+TM G RGVIP
Sbjct: 78 VDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIP 137
Query: 121 NSFDHIFTHISRSQNQ-----QYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVY 175
SF+++F+ I R + + +L + S++EIY E+I DLL + L L+E GV+
Sbjct: 138 RSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDS-ASAGLYLREHIKKGVF 196
Query: 176 VKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENH 235
V V S E V++ G +NR V +T+MN SSRSHA+F ITIE E + N
Sbjct: 197 VVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVN- 255
Query: 236 IRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD---GKSTHIPY 292
IR LNLVDLAGSERQ T A+G RLKEA IN SLS LG VI+ALVD GK H+ Y
Sbjct: 256 IRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCY 315
Query: 293 RDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKD 352
RDSKLT LL+DSLGGNAKT ++ANV P S ETL+TL +A RAK IKNK VNED +
Sbjct: 316 RDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQ- 374
Query: 353 ALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDD 412
+ + Q E+ RLK QL + + G+ E +++ + +
Sbjct: 375 GNVSQLQAEVKRLKEQLAELA------------------SGQTPPESFLTRDKKKTNYME 416
Query: 413 YWR---------EQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMED--LRREKDAAE 461
Y++ EQ++K IEK +ED +L E+ ++ K K ED +R EK E
Sbjct: 417 YFQEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEKLHKE 476
Query: 462 MLGAKIKAMESKLLVGGKNIVDHTNEQQK------ILEQKRQEIAEQKRREREIQ--QQM 513
G + + +LL +N + EQ + + + E+ RR R ++ ++
Sbjct: 477 SRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRA 536
Query: 514 ESRDEETL-ELKETYSSL---------QQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHI 563
+ D +T+ +L++ +S + QQ K +K LF+ + +KA++ +Q E
Sbjct: 537 QEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQLLQIQTELN 596
Query: 564 KERQELEQTQNELTRELKLK 583
+QE E+ + ELTR+ +L+
Sbjct: 597 NSKQEYEEFK-ELTRKRQLE 615
Score = 45.8 bits (107), Expect = 1e-04
Identities = 76/381 (19%), Positives = 149/381 (39%), Gaps = 44/381 (11%)
Query: 241 LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRL 300
L +++ E+Q +T +++ + K+ SL A VIS+L + + D K+
Sbjct: 932 LKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDS-----DKKVVAD 986
Query: 301 LQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIK-NKPRVNEDPKDALLREFQ 359
L + + +V ET+ TL+ + N K N V+ + L+++ +
Sbjct: 987 LMNQIQELRTSVCEKT---------ETIDTLKQELKDINCKYNSALVDREESRVLIKKQE 1037
Query: 360 EEIARLKAQLEKRSIGRRKRREKRREGGGSGG--------GGEEEEEEGEEGEEEGDDKD 411
+I LK L R + R+ E ++ + +EE K+
Sbjct: 1038 VDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKE 1097
Query: 412 DYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKE-KEKKMEDLRREKDAAEMLGAKIKAM 470
+E Q KL +K+ VE KMR L+ + ED + K K +
Sbjct: 1098 ALIQELQHKLN-QKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLL 1156
Query: 471 ESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETY--- 527
E+ Q++ +E R + ++ + E ++ E L +KE
Sbjct: 1157 ET---------------QEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREM 1201
Query: 528 SSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLII 587
+L+ E +K L +L +K + + + H + Q+L+ Q E +E K I+
Sbjct: 1202 ENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNH-PDNQQLKNEQEESIKERLAKSKIV 1260
Query: 588 ENFIPLEEKSKIMNRAFFDEE 608
E + ++ + + A +++E
Sbjct: 1261 EEMLKMKADLEEVQSALYNKE 1281
Score = 39.3 bits (90), Expect = 0.013
Identities = 35/168 (20%), Positives = 81/168 (48%), Gaps = 10/168 (5%)
Query: 412 DYWREQQEKLEIEKRAIVEDHSLVAEEKMRL-LKEKEKKMEDLRREKDAA--------EM 462
D R + EKL +E +A ++D +E M+ + + + +++ ++E + E+
Sbjct: 847 DNLRLENEKL-LESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMEL 905
Query: 463 LGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLE 522
L A+ + L ++ + + E K+LE RQE ++ + + +++ +E L
Sbjct: 906 LEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLA 965
Query: 523 LKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELE 570
++ SSL++ D K + L +++Q ++ + + E +QEL+
Sbjct: 966 TEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELK 1013
Score = 37.4 bits (85), Expect = 0.051
Identities = 53/278 (19%), Positives = 120/278 (43%), Gaps = 28/278 (10%)
Query: 344 PRVNEDPKDAL---LREFQEEIARLKAQLEKRSIGRRKRRE----------KRREGGGSG 390
P +NE +A+ LR QE+++ L+A+L++ K ++ + +E S
Sbjct: 705 PEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSE 764
Query: 391 GGGEEEEEEG--------EEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRL 442
+++E E+ +E K+D+ + + L + + ++ S V E
Sbjct: 765 RIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSF 824
Query: 443 LKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQ 502
+EK+ L ++ ++ KLL + D + Q+I++ + +++
Sbjct: 825 KTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRN 884
Query: 503 KRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSK--LQAVKAEIHDLQE 560
+ ++ + ++S +EL E ++ ++ ++ K+ SK L+ ++A + Q+
Sbjct: 885 LQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQK 944
Query: 561 EHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSK 598
E K Q++ + Q +L+ L E I EKS+
Sbjct: 945 ETAKCEQQMAKVQ-----KLEESLLATEKVISSLEKSR 977
Score = 33.9 bits (76), Expect = 0.57
Identities = 41/196 (20%), Positives = 90/196 (45%), Gaps = 32/196 (16%)
Query: 394 EEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDL 453
E +E+E E+G R + LE + ED + E +R+ KE+ ++ME+L
Sbjct: 1157 ETQEQEIEDG-----------RASKTSLEHLVTKLNEDREVKNAEILRM-KEQLREMENL 1204
Query: 454 RREK----DAAEMLGAKIKAMESKLLVGGKNIVDHT---NEQQKILEQKR------QEIA 500
R E + +L ++ ++ + +N D+ NEQ++ ++++ +E+
Sbjct: 1205 RLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEML 1264
Query: 501 EQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQE 560
+ K E+Q + +++ E L + + Q ++ ++L SKL+ ++ E
Sbjct: 1265 KMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLE-------EMYE 1317
Query: 561 EHIKERQELEQTQNEL 576
E + QE+E + ++
Sbjct: 1318 ERERTSQEMEMLRKQV 1333
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 298 bits (764), Expect = 9e-81
Identities = 200/486 (41%), Positives = 272/486 (55%), Gaps = 43/486 (8%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWN-- 66
SV+V VR RP N +E S D V ++ S+ NPK + + PK+FTFD Y W+
Sbjct: 5 SVKVAVRVRPFNARE--TSQDAKCVVSMQGNTTSIINPK-QSKDAPKSFTFDYSY-WSHT 60
Query: 67 -------AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVI 119
A Q ++Y + ++ +G+N IFAYGQTG GK+YTM G R +P ++G++
Sbjct: 61 STEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-RQEPGQQGIV 119
Query: 120 PNSFDHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVK 177
P + +F+ +S +Q+ Q Y V SY+EIY E +RDLL+ L ++E P G YV+
Sbjct: 120 PQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQ 179
Query: 178 DLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVI--TIECSE--VGLDGE 233
DLS S +I +M+ GN+ R+V ATNMNE SSRSHA+F I T C + GLD E
Sbjct: 180 DLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSE 239
Query: 234 NHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD-----GKST 288
+V K++LVDLAGSER +GA+G RLKE IN SL+ LG VISAL D KS
Sbjct: 240 ---KVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSD 296
Query: 289 HIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNE 348
IPYRDS LT LL+++LGGN++T M+A + PA N EETL+TLRYA+R K I+ +NE
Sbjct: 297 FIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINE 356
Query: 349 DPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGG----------GEEEEE 398
DP L+RE QEE+ARL+ L + + + E G G
Sbjct: 357 DPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSSP 416
Query: 399 EGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKD 458
GE E + E Q E + E ++AE +EK +K E LR E++
Sbjct: 417 TTHNGELEPSFSPN--TESQIGPEEAMERLQETEKIIAELN-ETWEEKLRKTEALRMERE 473
Query: 459 A--AEM 462
A AEM
Sbjct: 474 ALLAEM 479
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 296 bits (759), Expect = 4e-80
Identities = 212/598 (35%), Positives = 319/598 (53%), Gaps = 40/598 (6%)
Query: 1 MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFD 60
M++ + S++V+ R RP+N E DK + + V + K + FD
Sbjct: 1 MAETNNECSIKVLCRFRPLNQAEILRG-DKFIPIFQGDDSVVIGG---------KPYVFD 50
Query: 61 AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP 120
V+ N Q ++Y +V VL G+NGTIFAYGQT +GKT+TMEG DP+ G+IP
Sbjct: 51 RVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110
Query: 121 NSFDHIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDL 179
IF HI S +N ++ ++ SY EIY ++IRDLL +T L + E + +VK
Sbjct: 111 RIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTN-LSVHEDKNRVPFVKGC 169
Query: 180 SSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVG 239
+ S +EI V++ G NR V TNMNEHSSRSH+IF+I I+ + ++ E + G
Sbjct: 170 TERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIK--QENMETEQKLS-G 226
Query: 240 KLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTR 299
KL LVDLAGSE+ +KTGA+G L EA IN SLSALGNVISAL +G +++PYRDSK+TR
Sbjct: 227 KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTR 286
Query: 300 LLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVN-EDPKDALLREF 358
+LQDSLGGN +T M P+SYN ET +TL + RAK IKN VN E + +++
Sbjct: 287 ILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKY 346
Query: 359 QEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQ 418
++E + KAQ K +I + + R G + E E GEE + ++
Sbjct: 347 EKEKEKTKAQ--KETIAKLEAELSRWRNGEN--VPETERLAGEEAALGAELCEE--TPVN 400
Query: 419 EKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGG 478
+ I R E+ EE RL K+ + K +++ ++ E L ++ E +LLV
Sbjct: 401 DNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQE-ELLVST 459
Query: 479 KNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKT 538
+ + Q+ L + E K +E+ Q +E EL Y QEV+ K+
Sbjct: 460 RG---DNEKVQRELSHLQSENDAAKDEVKEVLQALE-------ELAVNYDQKSQEVEEKS 509
Query: 539 KKLKKLFSKLQ-------AVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIEN 589
++ + L +L ++++E+ LQE +R+ + + N L ++L +I+ N
Sbjct: 510 QQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGN 567
Score = 53.9 bits (128), Expect = 5e-07
Identities = 76/340 (22%), Positives = 138/340 (40%), Gaps = 68/340 (20%)
Query: 416 EQQEKLEIEKRAIVEDHSLVAEEKMRL----------LKEKEKKMEDLRREKDAAEMLGA 465
E + +E++KR + E + +++E +L LK+KE +D K A E+
Sbjct: 645 EYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALEL--- 701
Query: 466 KIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKE 525
MES H + L + R EI E+++ E++ + E +L+
Sbjct: 702 ---QMES-----------HREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQA 747
Query: 526 TYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHL 585
Y L+ E K+ KL+ E+ L E H + +Q+L+ + + REL+ H
Sbjct: 748 DYEKLKSEEHEKSTKLQ-----------ELTFLYERHEQSKQDLKGLEETVARELQTLHN 796
Query: 586 IIENFIPLEEKSKIMNRAFFDEEED---HWKLHPITRLENQQMMKRPVSAVGYKRPLSQH 642
+ + F+ + +++ A + E+ H + I+ LEN L Q
Sbjct: 797 LRKLFVQ-DVTTRVKKSAEMEPEDSGGIHSQKQKISFLENN---------------LEQL 840
Query: 643 ARM-SMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVD 701
++ ++R A R E L +L+ R T + A+ ++ A + A++D+ Q +
Sbjct: 841 TKVHKQLVRDNADLRCE---LPKLEKRLRATAE-RVKALEGALKEAKEGAMKDKRRYQQE 896
Query: 702 ASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQS 741
K R KS K G S+ + YP S
Sbjct: 897 VDRI------KEAVRYKSSGKRGHSAQIAKPVRPGHYPAS 930
Score = 33.5 bits (75), Expect = 0.74
Identities = 31/192 (16%), Positives = 90/192 (46%), Gaps = 6/192 (3%)
Query: 395 EEEEEGEEGEEEGDDKDDYWREQQEKLEIE-KRAIVEDH--SLVAEEKMRLLKEKEKKME 451
+E E ++ +E D + + + EKL+ + ++ E+H S +E L + E+ +
Sbjct: 719 DEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQ 778
Query: 452 DLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQ 511
DL K E + +++ + + + +++ + ++ + I QK++ ++
Sbjct: 779 DL---KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLEN 835
Query: 512 QMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQ 571
+E + +L + L+ E+ K+L+ +++A++ + + +E +K+++ +Q
Sbjct: 836 NLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQ 895
Query: 572 TQNELTRELKLK 583
+ + ++ K
Sbjct: 896 EVDRIKEAVRYK 907
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 290 bits (741), Expect = 4e-78
Identities = 235/699 (33%), Positives = 347/699 (49%), Gaps = 110/699 (15%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDV-KLGQVSVKNPKG----TAHEMPKTFTFDAVY 63
SV+V VR RPMN +EK ++ ++ K ++K P+G + E KTFT+D +
Sbjct: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
Query: 64 ---DWNAKQFELYDETFRPL----VDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR 116
D + + + F+ L V S +G+N +FAYGQTG+GK+YTM G GD
Sbjct: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Query: 117 GVIPNSFDHIFTHIS---RSQNQQYLVRASYLEIYQEEIRDLLSKDQTK--RLELKERPD 171
G+IP + +F+ I+ R + SYLEIY E +RDLL + +K L ++E P
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
Query: 172 TGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLD 231
G YV+DLS + ++ ++E +M+ GN NR+ AT MN+ SSRSHAIF TI+ ++ D
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIF--TIKFTQAKFD 237
Query: 232 GENHIR-VGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD------ 284
E V K++LVDLAGSER TGA G RLKE IN SL LGNVISAL D
Sbjct: 238 SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAA 297
Query: 285 -----GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKN 339
K +PYRDS LT LL+DSLGGN+KT+M+A + PA N ETL+TLRYANRAKN
Sbjct: 298 NTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKN 357
Query: 340 IKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEE 399
I NKP +NED L+RE + EIARLK L + + + + EE+ ++
Sbjct: 358 IINKPTINEDANVKLIRELRAEIARLKTLLAQGN-------QIALLDSPTALSMEEKLQQ 410
Query: 400 GEEGEEE-GDDKDDYWREQQEKLEIEKRAI------------------VEDHSLVAEEKM 440
E +E + + W E Q L+ + A+ ++D L +
Sbjct: 411 NEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIIL 470
Query: 441 RLLKEKEKKME---------------DLRREKDAAEMLGAKIKAME---SKLLVGGKNIV 482
LKE + + DL E E +G + + S+ V G IV
Sbjct: 471 YHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIV 530
Query: 483 D--HTNEQQKILEQKR--------QEIAEQKRRER-------EIQQQMESRDEETLELKE 525
+ H N+ IL + +E A+ + + + + S+ E L
Sbjct: 531 EATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVM 590
Query: 526 TYS-----SLQQEVDI-----KTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNE 575
Y+ QQ ++ K K ++++ K ++ KAE+ +Q+E +R+E E Q +
Sbjct: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQ 650
Query: 576 LTRE---LKLKHLIIENFIP--LEEKSKIMNRAFFDEEE 609
+ ++ LK + IEN + L EK K +++E
Sbjct: 651 IRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQE 689
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/202 (20%), Positives = 94/202 (46%), Gaps = 20/202 (9%)
Query: 487 EQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKK--- 543
E+ + LE KR+ I E + +++ + ++E +E ++ +Q ++ + + LK+
Sbjct: 604 EELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSF 663
Query: 544 -LFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNR 602
+ +KL+ + AE +EE ++E+QE+ EL+ K E F+ ++E+ + +
Sbjct: 664 HIENKLKDLLAEKEKFEEERLREQQEI---------ELQKKRQEEETFLRVQEELQRLKE 714
Query: 603 AFFDEEEDHW----KLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAE 658
+E+ + + +L + + +++Q K + + + + + + R + E
Sbjct: 715 LNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQE 774
Query: 659 NIVLL---ELDMPSRTTRDYEG 677
I LL E+ RD EG
Sbjct: 775 MIQLLRRGEVQWVEEEKRDLEG 796
Score = 40.8 bits (94), Expect = 0.005
Identities = 37/173 (21%), Positives = 86/173 (49%), Gaps = 12/173 (6%)
Query: 444 KEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQK 503
+++ +++E L ++ E + K K+ +++L + + E + + Q R++ K
Sbjct: 600 RQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLK 659
Query: 504 RREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLK-----KLFSKLQAVKAEIHDL 558
RR I+ +++ E + +E QQE++++ K+ + ++ +LQ +K ++
Sbjct: 660 RRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNE 719
Query: 559 QEEHIKERQELEQTQNELTRE---LKLKHLIIENFIPLEEKSKIMNRAFFDEE 608
+ E + QEL+Q Q E + L+L+ +E +EK ++M A +E+
Sbjct: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEE----QEKEQVMLVAHLEEQ 768
Score = 36.6 bits (83), Expect = 0.087
Identities = 78/386 (20%), Positives = 158/386 (40%), Gaps = 51/386 (13%)
Query: 239 GKLNLVDLAGSERQAKTGAQGERLKEATKINL-SLSALGNVISALVDGKSTHIPYRDSKL 297
G + L+ L+GS+ G ++ EAT +N ++ LG + R+ +
Sbjct: 510 GTVTLIPLSGSQ----CSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRK 565
Query: 298 TRLLQD-SLG--------GNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNE 348
+ LL SL N VM+ N G + ++ + ++ K I+ +
Sbjct: 566 SGLLSSFSLSMTDLSKSRENLSAVMLYNPG-LEFERQQREELEKLESKRKLIEEMEEKQK 624
Query: 349 DPKDALLREFQEEIARLKAQLEKRSIGRRKRREK-RREGGGSGGGGEEEEEEGEEGEEEG 407
K A L Q+E+ + + E + RK+ E +R ++ E E+ EEE
Sbjct: 625 SDK-AELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEER 683
Query: 408 DDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKI 467
REQQE +E++K+ E+ L +E+++ LKE L
Sbjct: 684 ------LREQQE-IELQKKRQEEETFLRVQEELQRLKE-----------------LNNNE 719
Query: 468 KAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETY 527
KA + ++ + +EQ LE +++ + EQ++ Q + + EE L K+
Sbjct: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKE----QVMLVAHLEEQLREKQEM 775
Query: 528 SSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLII 587
L + +++ + +K L+ ++ + ++E ++ E+ + R + K +
Sbjct: 776 IQLLRRGEVQWVEEEK--RDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQL 833
Query: 588 ENFIPLE----EKSKIMNRAFFDEEE 609
+ LE ++ I+ + +E+E
Sbjct: 834 VKLVNLEKDLVQQKDILKKEVQEEQE 859
Score = 32.3 bits (72), Expect = 1.6
Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 7/162 (4%)
Query: 417 QQEKLEIEKRAIVEDHSLVAEEKM-RLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLL 475
Q+EK+ +++ I+E E + R L E++ L+R LG +I+ KL
Sbjct: 982 QEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHST----LGMEIEEQRQKLA 1037
Query: 476 VGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVD 535
+ + Q + ++ +Q+R E EIQQ + E K+ + +L+ +V
Sbjct: 1038 SLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVA 1097
Query: 536 IKTKKLKKLFSKL-QAVKAEIHDLQEEHIKER-QELEQTQNE 575
+ + S L + A I+ EE ++ R Q+L + +E
Sbjct: 1098 SSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISE 1139
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 288 bits (738), Expect = 1e-77
Identities = 216/622 (34%), Positives = 326/622 (52%), Gaps = 74/622 (11%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMP--KTFTFDAVYDWN 66
+V V VR RP+N +E++ + QV K +++ K+F FD V+ N
Sbjct: 6 AVAVCVRVRPLNSREESLG---------ETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGN 56
Query: 67 AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHI 126
+Y+E P++DS +QG+NGTIFAYGQT +GKTYTM G + GVIP + I
Sbjct: 57 ETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTM---MGSEDHLGVIPRAIHDI 113
Query: 127 FTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQ-TKRLELKERPDTGVYVKDLSSFVTK 185
F I + ++++L+R SY+EIY E I DLL Q K L ++E + VYV DL+ V
Sbjct: 114 FQKIKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVY 173
Query: 186 SVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVG--LDGENHIRVGKLNL 243
+ + + G ++R G T MN+ SSRSH IF + +E E G + E ++V LNL
Sbjct: 174 TSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNL 233
Query: 244 VDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGK-STHIPYRDSKLTRLLQ 302
VDLAGSER A+TGA G RLKE IN SL LG VI L DG+ I YRDSKLTR+LQ
Sbjct: 234 VDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQ 293
Query: 303 DSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKD-ALLREFQEE 361
+SLGGNAKT ++ + P S+ +ETLT L++A+ AK +KN P VNE D ALL+ +++E
Sbjct: 294 NSLGGNAKTRIICTITPVSF--DETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKE 351
Query: 362 IARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKL 421
I LK QLE+ S+ R + E ++ + ++KD + Q EK+
Sbjct: 352 IMDLKKQLEEVSLETR-----------------AQAMEKDQLAQLLEEKDLLQKVQNEKI 394
Query: 422 EIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNI 481
E R +V SL +++++ +R++ LG KI M++ N
Sbjct: 395 ENLTRMLVTSSSLTLQQELK-----------AKRKRRVTWCLG-KINKMKN------SNY 436
Query: 482 VDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKL 541
D N I + + REI + + S + +T S ++ K
Sbjct: 437 ADQFNIPTNITTKTHKLSINLL---REIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQ 493
Query: 542 KKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHL-IIENFIPLEEKSKIM 600
+ + S+L +++A+ +L ++ + R E E+ ELKLK ++ F LE K+K
Sbjct: 494 ENIESELNSLRADYDNLVLDYEQLRTEKEE------MELKLKEKNDLDEFEALERKTK-- 545
Query: 601 NRAFFDEEEDHWKLHPITRLEN 622
++++ +H I+ L+N
Sbjct: 546 ------KDQEMQLIHEISNLKN 561
Score = 52.4 bits (124), Expect = 2e-06
Identities = 77/377 (20%), Positives = 162/377 (42%), Gaps = 65/377 (17%)
Query: 263 KEATKINLSLSALGNVISAL---VDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGP 319
KEA K + SL AL +S + K+ + R +++ +L ++ L T+
Sbjct: 852 KEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL-KEQLENRDSTLQTVER-- 908
Query: 320 ASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKR 379
E+TL T + + +K + +D K L Q E +LK+ +
Sbjct: 909 -----EKTLITEKLQQTLEEVKTLTQEKDDLKQ-LQESLQIERDQLKSDIHDTVNMNIDT 962
Query: 380 REKRREGGGS------------GGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRA 427
+E+ R S EE E G+ KD++ QQ+ + I+K+
Sbjct: 963 QEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEF---QQKMVGIDKKQ 1019
Query: 428 IVE---DHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDH 484
+E +L A+ K + E+++K+ L +EK+ + + + A + +L K ++
Sbjct: 1020 DLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEM 1079
Query: 485 TNEQQKILE------QKRQEIAEQKRRE----------------------REIQQQMESR 516
T E Q+ L +K+QEI Q++ +E QQ++ +
Sbjct: 1080 TIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEK 1139
Query: 517 DEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNE- 575
++ L ++E S +Q++++ +++ L ++L+ + + ++ E ++ Q+L + E
Sbjct: 1140 QQQLLNVQEEMSEMQKKIN----EIENLKNELKNKELTLEHMETERLELAQKLNENYEEV 1195
Query: 576 --LTRELKLKHLIIENF 590
+T+E K+ + ++F
Sbjct: 1196 KSITKERKVLKELQKSF 1212
Score = 48.9 bits (115), Expect = 2e-05
Identities = 58/309 (18%), Positives = 137/309 (44%), Gaps = 38/309 (12%)
Query: 325 EETLTTLR--YANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREK 382
+ET+ LR + + I N + E DAL + LK Q E R I +E+
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQ------DLKIQEELR-IAHMHLKEQ 1786
Query: 383 RREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRL 442
+ G E+ ++ +++ ++ + +E+ ++L+ +H L+ +K
Sbjct: 1787 QETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELK------ANEHQLITLKKD-- 1838
Query: 443 LKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQK------- 495
+ E +KK+ ++ + K + + +E + L + + ++ E + +++++
Sbjct: 1839 VNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVE 1898
Query: 496 ----------RQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLF 545
++ + E K R+ EIQQ++++ + E KET L++++ KT ++ +
Sbjct: 1899 ETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQ 1958
Query: 546 SKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFF 605
L K E+ ++ I+E Q+ E + ++ + H I L+++ + N +
Sbjct: 1959 KDLDKSKDEL----QKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQ 2014
Query: 606 DEEEDHWKL 614
D+++L
Sbjct: 2015 SVRMDNFQL 2023
Score = 48.5 bits (114), Expect = 2e-05
Identities = 69/319 (21%), Positives = 141/319 (44%), Gaps = 47/319 (14%)
Query: 299 RLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREF 358
RLL D L + V E + T R A + +K K + ++ + LL
Sbjct: 1088 RLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQ 1147
Query: 359 QE---------EIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDD 409
+E EI LK +L+ + + +R E ++ E E +
Sbjct: 1148 EEMSEMQKKINEIENLKNELKNKELTLEHMETERLELA-------QKLNENYEEVKSITK 1200
Query: 410 KDDYWREQQEKLEIEKRAI------VEDHSLVAEEKMRL----LKEKEKKMEDLRR---E 456
+ +E Q+ E E+ + +E L +E++++ LKE ++ +++LRR E
Sbjct: 1201 ERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE 1260
Query: 457 KDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQ---QQM 513
K A + ++ +KL + + +E+Q++L + E++E + E++ +Q
Sbjct: 1261 KTAQIINTQDLEKSHTKL----QEEIPVLHEEQELLPNVK-EVSETQETMNELELLTEQS 1315
Query: 514 ESRDEETL--------ELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKE 565
++D TL L E + Q+E+ TK+ L + +A++ + HD +EHI+E
Sbjct: 1316 TTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVK-HDQLKEHIRE 1374
Query: 566 R-QELEQTQNELTRELKLK 583
+++++Q++ + L +K
Sbjct: 1375 TLAKIQESQSKQEQSLNMK 1393
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/203 (22%), Positives = 93/203 (45%), Gaps = 30/203 (14%)
Query: 397 EEEGEEGEEEGDDKDDYWREQQ------EKLEIEKRAIVEDHSLVAEEKMRL----LKEK 446
+E +E + +KDD R Q+ ++L+ + IV H L EE++++ LKE+
Sbjct: 1431 QESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKH-LETEEELKVAHCCLKEQ 1489
Query: 447 EKKMEDLR----REKDAAEMLGAKIKAMESKLLVGGKNIVDHTNE----QQKILEQKRQE 498
E+ + +LR ++ + +++A+ KL + I + + Q +++K E
Sbjct: 1490 EETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNE 1549
Query: 499 IAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDL 558
+ + K + ++S + + LEL Q+E+ I K+ K E+ +
Sbjct: 1550 LKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKE-----------KEEMKRV 1598
Query: 559 QEEHIKERQELEQTQNELTRELK 581
QE ER +L++ E+ ++K
Sbjct: 1599 QEALQIERDQLKENTKEIVAKMK 1621
Score = 44.7 bits (104), Expect = 3e-04
Identities = 66/312 (21%), Positives = 142/312 (45%), Gaps = 33/312 (10%)
Query: 394 EEEEEEGEEGEEEGDDKDDYWREQQEKLEIE----KRAIVEDHSLVAEEKMRLLKEKEKK 449
+E+EE E +K+ Q++LE + I E + + ++ + E ++K
Sbjct: 1487 KEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK 1546
Query: 450 MEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREI 509
+ +L++ K+ + + ++++ESK+L + TN L++ ++EI + + E+
Sbjct: 1547 VNELKQFKEHRKAKDSALQSIESKML-------ELTNR----LQESQEEIQIMIKEKEEM 1595
Query: 510 QQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQE-EHIKERQE 568
++ E+ E +LKE + ++ ++++ + F K+ AV + E EH+KE+ E
Sbjct: 1596 KRVQEALQIERDQLKENTKEIVAKMK-ESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFE 1654
Query: 569 LEQ--TQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQM- 625
++ +N T ++L ++ EN LEE R+ E +D + ++E Q+
Sbjct: 1655 TQKLNLENIETENIRLTQILHEN---LEEM-----RSVTKERDDLRSVEETLKVERDQLK 1706
Query: 626 --MKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPK 683
++ ++ K+ + M + E + IV + + S +D E A K
Sbjct: 1707 ENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALK 1766
Query: 684 VQAALDAALQDE 695
Q D +Q+E
Sbjct: 1767 AQ---DLKIQEE 1775
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/172 (19%), Positives = 85/172 (49%), Gaps = 22/172 (12%)
Query: 404 EEEGDDKDDYWREQQ--EKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAE 461
EE G KDD Q + + E + H ++ +L+E E+ +++ A+
Sbjct: 796 EEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQ 855
Query: 462 MLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETL 521
+ + A++++L + + + L++K +E+ E+ ++++Q+E+RD
Sbjct: 856 KFDSSLGALKTEL-----------SYKTQELQEKTREVQERLNEMEQLKEQLENRD---- 900
Query: 522 ELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQ 573
T ++++E + T+KL++ +++ + E DL++ ++E ++E+ Q
Sbjct: 901 ---STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQ--LQESLQIERDQ 947
Score = 39.3 bits (90), Expect = 0.013
Identities = 39/164 (23%), Positives = 74/164 (45%), Gaps = 9/164 (5%)
Query: 415 REQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAA----EMLGAKIKAM 470
+E+ ++L + + D L + L+ K+K DL +E +A L + I
Sbjct: 652 KEKMKELATTYKQMENDIQLYQSQ----LEAKKKMQVDLEKELQSAFNEITKLTSLIDGK 707
Query: 471 ESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSL 530
K L+ + + QK L ++ +E E R E + +++S E L++
Sbjct: 708 VPKDLLCNLELEGKITDLQKELNKEVEE-NEALREEVILLSELKSLPSEVERLRKEIQDK 766
Query: 531 QQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQN 574
+E+ I T + KLFS++ ++ + L EE K + +L TQ+
Sbjct: 767 SEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQS 810
Score = 37.0 bits (84), Expect = 0.067
Identities = 92/520 (17%), Positives = 209/520 (40%), Gaps = 75/520 (14%)
Query: 116 RGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVY 175
RG++ + I ++ ++A L+I QEE+R + LKE+ +T
Sbjct: 1741 RGIVSEKTNEISNMQKDLEHSNDALKAQDLKI-QEELR-------IAHMHLKEQQET--- 1789
Query: 176 VKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENH 235
+ L V++ ++ ++ + + + E + H + + + +E
Sbjct: 1790 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET------- 1842
Query: 236 IRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDS 295
+ + ++ ++Q K + E +NL+ N+ K R
Sbjct: 1843 ----QKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVE 1898
Query: 296 KLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRA-KNIKNKPRVNEDPKDAL 354
+ +L +D L + + ++ +++ L T R ++ K +K R K
Sbjct: 1899 ETLKLERDQLKESLQETKARDL-----EIQQELKTARMLSKEHKETVDKLREKISEKTIQ 1953
Query: 355 LREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYW 414
+ + Q+++ + K +L+K+ +K+ + ++ E E+ +++ + ++
Sbjct: 1954 ISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSM 2013
Query: 415 RE-QQEKLEIEKRA--IVEDHSLVAEEK--MRLLKEKEKKMED----LRREKDAAEMLGA 465
+ + + ++ K+ +E+ +VA+E+ +R +KE K D RE A +
Sbjct: 2014 QSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNH 2073
Query: 466 KIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKE 525
++K E +LL G+ H E L +K I E +R E+ E + +L+L++
Sbjct: 2074 QVKP-EKRLLSDGQQ---HLTES---LREKCSRIKELLKRYSEMDDHYECLNRLSLDLEK 2126
Query: 526 TYSSLQQEVDIK-----------TKKLKKLFSKLQAVKAEIHDLQEE---------HIKE 565
Q+E+ ++ TK ++KLF+ Q E H + ++ IKE
Sbjct: 2127 EIE-FQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKE 2185
Query: 566 RQE----------LEQTQNELTRELKLKHLIIENFIPLEE 595
Q +++ + + +K++HL + +P E
Sbjct: 2186 EQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRE 2225
Score = 34.7 bits (78), Expect = 0.33
Identities = 43/190 (22%), Positives = 87/190 (45%), Gaps = 17/190 (8%)
Query: 396 EEEEGEEGEEEGDDKDDYWR-EQQEKLEIEKRAIVEDHSLVAEEK------MRLLKEKEK 448
E+EE E +E +D D++ E++ K + E + I E +L K L E
Sbjct: 520 EKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSS 579
Query: 449 KMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRRERE 508
K+E LR ++D + L I +S+ L K + ++ E + +Q +Q + + + +
Sbjct: 580 KVELLREKEDQIKKLQEYI---DSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALD 636
Query: 509 IQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQE 568
+++ E LELKE L K++ + +Q ++++ ++ + +E
Sbjct: 637 AKRESAFLRSENLELKEKMKEL-------ATTYKQMENDIQLYQSQLEAKKKMQVDLEKE 689
Query: 569 LEQTQNELTR 578
L+ NE+T+
Sbjct: 690 LQSAFNEITK 699
Score = 33.5 bits (75), Expect = 0.74
Identities = 51/228 (22%), Positives = 96/228 (42%), Gaps = 30/228 (13%)
Query: 420 KLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLG-----------AKIK 468
++E+E+ + E EE L KE++ +L+ K+A E+ AKI+
Sbjct: 1325 RIEMERLRLNEKFQESQEEIKSLTKERD----NLKTIKEALEVKHDQLKEHIRETLAKIQ 1380
Query: 469 AMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYS 528
+SK N+ + NE KI+ + Q + R I+ +M + E +
Sbjct: 1381 ESQSKQ-EQSLNMKEKDNETTKIVSEMEQFKPKDSALLR-IEIEMLGLSKRLQESHDEMK 1438
Query: 529 SLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQEL----------EQTQNELTR 578
S+ +E D + + L S+ +K I ++ +H++ +EL E+T NEL
Sbjct: 1439 SVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRV 1498
Query: 579 ELKLKHLIIENFIPLEE--KSKIMNR-AFFDEEEDHWKLHPITRLENQ 623
L K I E K+ N+ E+E+ + + I+ ++ +
Sbjct: 1499 NLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK 1546
Score = 31.2 bits (69), Expect = 3.7
Identities = 30/143 (20%), Positives = 61/143 (42%), Gaps = 14/143 (9%)
Query: 427 AIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGK-NIVDHT 485
AI+ + + E + KE E +DL+ K+ E L + +++ L G + N
Sbjct: 2309 AIMNESTEFEERSATISKEWE---QDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQD 2365
Query: 486 NEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLF 545
N+ + + Q E + RE++ + E + + +Q+E+++ + KL
Sbjct: 2366 NKNPHVTSRATQLTTE---KIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQ 2422
Query: 546 SK-------LQAVKAEIHDLQEE 561
+K L+ K I LQ++
Sbjct: 2423 AKVHESNKCLEKTKETIQVLQDK 2445
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 287 bits (735), Expect = 2e-77
Identities = 188/478 (39%), Positives = 268/478 (56%), Gaps = 52/478 (10%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDW 65
S SV+V VR RP N +E S + + ++ S+ NPK E PK+F+FD Y W
Sbjct: 2 SGASVKVAVRVRPFNSRE--TSKESKCIIQMQGNSTSIINPKNPK-EAPKSFSFDYSY-W 57
Query: 66 N---------AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR 116
+ A Q +Y++ + ++ +G+N IFAYGQTG GK+YTM G + + +
Sbjct: 58 SHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-KQEESQA 116
Query: 117 GVIPNSFDHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGV 174
G+IP + +F I+ + N++ Y V SY+EIY E +RDLL+ L ++E P G
Sbjct: 117 GIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP 176
Query: 175 YVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGEN 234
YV+DLS S +I +M+ GN+ R+V ATNMNE SSRSHA+F TI ++ D E
Sbjct: 177 YVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVF--TIVFTQKKHDNET 234
Query: 235 HI---RVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD-----GK 286
++ +V K++LVDLAGSER TGA+G RLKE IN SL+ LG VISAL + K
Sbjct: 235 NLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKK 294
Query: 287 STHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRV 346
+ IPYRDS LT LL+++LGGN++T MVA + PA N +ETL+TLRYA+RAK IK +
Sbjct: 295 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVI 354
Query: 347 NEDPKDALLREFQEEIARLKAQLEKRSIG-----------------------RRKRREKR 383
NEDP L+RE +EE+ RLK L + +G
Sbjct: 355 NEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVTSI 414
Query: 384 REGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLE---IEKRAIVEDHSLVAEE 438
+E S GGEE E +E E+ + ++ W E+ K E +E+ A++ + + E
Sbjct: 415 QERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIRE 472
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 287 bits (735), Expect = 2e-77
Identities = 188/478 (39%), Positives = 268/478 (56%), Gaps = 52/478 (10%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDW 65
S SV+V VR RP N +E S + + ++ S+ NPK E PK+F+FD Y W
Sbjct: 2 SGASVKVAVRVRPFNSRE--TSKESKCIIQMQGNSTSIINPKNPK-EAPKSFSFDYSY-W 57
Query: 66 N---------AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR 116
+ A Q +Y++ + ++ +G+N IFAYGQTG GK+YTM G + + +
Sbjct: 58 SHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-KQEESQA 116
Query: 117 GVIPNSFDHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGV 174
G+IP + +F I+ + N++ Y V SY+EIY E +RDLL+ L ++E P G
Sbjct: 117 GIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP 176
Query: 175 YVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGEN 234
YV+DLS S +I +M+ GN+ R+V ATNMNE SSRSHA+F TI ++ D E
Sbjct: 177 YVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVF--TIVFTQKKHDNET 234
Query: 235 HI---RVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD-----GK 286
++ +V K++LVDLAGSER TGA+G RLKE IN SL+ LG VISAL + K
Sbjct: 235 NLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKK 294
Query: 287 STHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRV 346
+ IPYRDS LT LL+++LGGN++T MVA + PA N +ETL+TLRYA+RAK IK +
Sbjct: 295 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVI 354
Query: 347 NEDPKDALLREFQEEIARLKAQLEKRSIG-----------------------RRKRREKR 383
NEDP L+RE +EE+ RLK L + +G
Sbjct: 355 NEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVTSI 414
Query: 384 REGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLE---IEKRAIVEDHSLVAEE 438
+E S GGEE E +E E+ + ++ W E+ K E +E+ A++ + + E
Sbjct: 415 QERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIRE 472
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 287 bits (735), Expect = 2e-77
Identities = 208/587 (35%), Positives = 316/587 (53%), Gaps = 56/587 (9%)
Query: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
V+V VR RP+ KE ++ V V QV + + FTFD V+ N+ Q
Sbjct: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDR--------VFTFDFVFGKNSTQ 57
Query: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEG------IRGDPEKRGVIPNSF 123
E+Y+ +PLV S+++G+N T+FAYGQTG+GKTYT+ G + G ++G+IP +
Sbjct: 58 DEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEG---QKGIIPRAI 114
Query: 124 DHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQT-KRLELKERPDTGVYVKDLSSF 182
IF IS + + V+ SY+E+Y+E++RDLL + + K L ++E +
Sbjct: 115 QEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKEC 174
Query: 183 VTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITI----ECSEVGLDGE----N 234
+S E+ ++ +GN R G T MNEHSSRSHAIF I+I + E DG
Sbjct: 175 HVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPR 234
Query: 235 HIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIPY 292
HI V K + VDLAGSER KTG GER KE+ +IN L ALGNVISAL D KS+HIPY
Sbjct: 235 HI-VSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPY 293
Query: 293 RDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKD 352
RD+K+TRLL+DSLGG+AKTVM+ V P+S N +E+L +L+YANRA+NI+NKP VN P+
Sbjct: 294 RDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPES 353
Query: 353 ALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDD 412
+ E + EI L+ L+ + G + + REG EE+ + + E
Sbjct: 354 DRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQC 413
Query: 413 YWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMES 472
E L ++D + E++ L+E ++++R+ + S
Sbjct: 414 CVEEAFTFL-----VDLKDTVRLNEKQQHKLQEWFNMIQEVRK------------AVLTS 456
Query: 473 KLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
+GG ++ + +L+ KR E K+ + + +++ LE+KE L+
Sbjct: 457 FRGIGGTASLEEGPQHVTVLQLKR----ELKKCQCVLAADEVVFNQKELEVKE----LKN 508
Query: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQEL-EQTQNELTR 578
+V + ++ K L+ + +++ LQ E I E+Q L +Q ELT+
Sbjct: 509 QVQMMVQENKGHAVSLKEAQ-KVNRLQNEKIIEQQLLVDQLSEELTK 554
Score = 48.9 bits (115), Expect = 2e-05
Identities = 81/397 (20%), Positives = 177/397 (44%), Gaps = 74/397 (18%)
Query: 240 KLNLVDLAGSERQAKTGAQGERLKEAT-KINLSLSALGNVISALVDGKSTHIPYRDSKLT 298
+LNL L SER Q +++E T I + + +I D KS Y K+T
Sbjct: 706 ELNLQKLKNSERILTEAKQ--KMRELTINIKMKEDLIKELIKTGNDAKSVSKQY-SLKVT 762
Query: 299 RLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREF 358
+L D+ AK ++ ET L+ ++NK + K L +EF
Sbjct: 763 KLEHDA--EQAKVELI-----------ETQKQLQ------ELENKDLSDVAMKVKLQKEF 803
Query: 359 QEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQ 418
++++ K +++ + ++K+++ ++ S + E+ E E+ D +
Sbjct: 804 RKKMDAAKLRVQ---VLQKKQQDSKKLASLS----IQNEKRANELEQSVDHM------KY 850
Query: 419 EKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMES---KLL 475
+K++++++ E+ ++ ++K ++K+++++ + E L K + +++ K
Sbjct: 851 QKIQLQRKLREENEK--RKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRR 908
Query: 476 VGGKNIVDHT---NEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
G +DH +EQ+K L+++ +++ Q++ E++ ++ R E + KE LQ+
Sbjct: 909 KGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKR-EAIVSKKEAL--LQE 965
Query: 533 EVDIKTKKLK----------KLFSKLQAVKAEIHD--------LQEEHIKERQELEQTQN 574
+ ++ KKL+ K+ ++L ++ E+ + EE K +++E Q
Sbjct: 966 KSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQK 1025
Query: 575 ELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDH 611
E + K +H + E K+ N EE+H
Sbjct: 1026 EKDQLQKRRHNVDE---------KLKNGRVLSPEEEH 1053
Score = 39.3 bits (90), Expect = 0.013
Identities = 41/207 (19%), Positives = 98/207 (47%), Gaps = 19/207 (9%)
Query: 395 EEEEEGEEGEEEGDD-KDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDL 453
+ ++E ++ + E +D K D +E QE L ++K E A++KMR L K EDL
Sbjct: 681 DTQDETQKSDLENEDLKIDCLQESQE-LNLQKLKNSERILTEAKQKMRELTINIKMKEDL 739
Query: 454 RRE--------KDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRR 505
+E K ++ K+ +E +++ + Q++ + ++A + +
Sbjct: 740 IKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKL 799
Query: 506 EREIQQQMESRD--EETLELKETYSSLQQEVDIKTKK----LKKLFSKLQAVKAEIHDLQ 559
++E +++M++ + L+ K+ S + I+ +K L++ ++ K ++
Sbjct: 800 QKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKL 859
Query: 560 EEHIKERQELE---QTQNELTRELKLK 583
E ++R++L+ + + +E++LK
Sbjct: 860 REENEKRKQLDAVIKRDQQKIKEIQLK 886
Score = 35.8 bits (81), Expect = 0.15
Identities = 38/184 (20%), Positives = 79/184 (42%), Gaps = 20/184 (10%)
Query: 481 IVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKK 540
++ H EQ K+L + + ++ + E + + R ++ ++ SL + D + +
Sbjct: 627 LLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDET 686
Query: 541 LKKLFSKLQAVKAEIHDLQEEHIKERQELE----------QTQNELTRELKLKHLIIENF 590
K S L+ +I LQE Q+L+ Q ELT +K+K +I+
Sbjct: 687 QK---SDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKEL 743
Query: 591 IPLEEKSKIMNRAF------FDEEEDHWKLHPI-TRLENQQMMKRPVSAVGYKRPLSQHA 643
I +K +++ + + + + K+ I T+ + Q++ + +S V K L +
Sbjct: 744 IKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEF 803
Query: 644 RMSM 647
R M
Sbjct: 804 RKKM 807
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 286 bits (732), Expect = 5e-77
Identities = 224/721 (31%), Positives = 351/721 (48%), Gaps = 128/721 (17%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVV-----DVDVKLGQVSVKNPKGTAHEMPKTFTFDAVY 63
S++V+ R RP+N E DK + D V +GQ K + FD V
Sbjct: 8 SIKVMCRFRPLNEAEILRG-DKFIPKFKGDETVVIGQ-------------GKPYVFDRVL 53
Query: 64 DWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSF 123
N Q ++Y+ + +V VL+G+NGTIFAYGQT +GKT+TMEG DP+ G+IP
Sbjct: 54 PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
Query: 124 DHIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSF 182
IF HI S +N ++ ++ SY EIY ++IRDLL +T L + E + YVK +
Sbjct: 114 HDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN-LAVHEDKNRVPYVKGCTER 172
Query: 183 VTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLN 242
S +E+ V++ G NR V TNMNEHSSRSH+IF+I I+ V + + GKL
Sbjct: 173 FVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS---GKLY 229
Query: 243 LVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQ 302
LVDLAGSE+ +KTGA+G L EA IN SLSALGNVISAL +G TH+PYRDSK+TR+LQ
Sbjct: 230 LVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQ 289
Query: 303 DSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVN-EDPKDALLREFQEE 361
DSLGGN +T +V P+ +N ET +TL + RAK IKN VN E + +++++E
Sbjct: 290 DSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKE 349
Query: 362 ----------IARLKAQLEKRSIGRRKRREKRREGGG--------------------SGG 391
I L+ +L + G +++ +G
Sbjct: 350 KEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGI 409
Query: 392 GGEEEEEEGEEGE---EEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEK 448
EE+E+ EE + DDKDD +Q + E K+ +++ L+A + ++ EK
Sbjct: 410 STEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTR----RDYEK 465
Query: 449 KMEDLRR---EKDAAEMLGAKIKAMESKLLVG----GKNIVDHTNEQQKILEQKRQEIAE 501
E+L R E +AA+ ++ +L V + + D T +++ ++ Q+
Sbjct: 466 IQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTT 525
Query: 502 QKRREREIQQQMESRDEETLELKETYSSLQQEV----------DIKTKK----------- 540
+RE+ Q E + + E + L +++ D+KT
Sbjct: 526 LTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFT 585
Query: 541 -----LKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT--------RELKLKHL-- 585
+ K+ S+++++ L+ + +++ ++ EL E K+K L
Sbjct: 586 MARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTD 645
Query: 586 ------------------IIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMK 627
+ E L + K+ +F D+E++H +TRL++ + MK
Sbjct: 646 YMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEH-----LTRLQDAEEMK 700
Query: 628 R 628
+
Sbjct: 701 K 701
Score = 49.3 bits (116), Expect = 1e-05
Identities = 53/274 (19%), Positives = 122/274 (44%), Gaps = 34/274 (12%)
Query: 338 KNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEE 397
+N++ K R E+ +D+L EE+A+L+AQ + + + + ++ ++
Sbjct: 648 QNMEQKRRQLEESQDSL----SEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKAL 703
Query: 398 EEGEEGEEEGDDKD---------------DYWREQQEKLEIEKRAIVEDHSLVAEEKMRL 442
E+ E E K D R+ +KL++E+ + D++ + E
Sbjct: 704 EQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIED--- 760
Query: 443 LKEKEKKMEDLRREKDAAEMLGAKIKAME---SKLLVGGKN-----IVDHTNEQQKILEQ 494
+E+E K+E L D E +K +E S+ L N + D T +K +E
Sbjct: 761 -QEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVEL 819
Query: 495 KRQE---IAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAV 551
+ A QK++ ++ +E + +L + L+ E+ K+L+ +++A+
Sbjct: 820 DNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 879
Query: 552 KAEIHDLQEEHIKERQELEQTQNELTRELKLKHL 585
++ + + +E +++R+ +Q + + ++ K++
Sbjct: 880 ESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNM 913
Score = 38.5 bits (88), Expect = 0.023
Identities = 65/325 (20%), Positives = 136/325 (41%), Gaps = 39/325 (12%)
Query: 320 ASYNVEETLTTLR-----YANRAKNIKNKPRVNEDPKDALLREFQE--EIARLKAQLEKR 372
A V+E L L Y +++ +++K R NE D L ++ R +QL++
Sbjct: 480 AKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL 539
Query: 373 SIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDH 432
S ++KR + ++ GE G G + K + ++E+
Sbjct: 540 SNHQKKRATEILN--------LLLKDLGEIGGIIGTN--------DVKTLADVNGVIEEE 583
Query: 433 SLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKIL 492
+A + +K + K + + ++ ++A+M + + L + ++ + K L
Sbjct: 584 FTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSL 643
Query: 493 EQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVK 552
Q + +++R+ E Q +S EE +L+ EV + K+ K+ ++LQ +
Sbjct: 644 TDYMQNMEQKRRQLEESQ---DSLSEELAKLRA--QEKMHEVSFQDKE-KEHLTRLQDAE 697
Query: 553 AEIHDLQEEHIKERQELEQTQ-NELTRELKLKHLIIENFIPLEEK--------SKIMNRA 603
E+ E+ ++ +E Q Q + L E++ K II+ L +K S N+
Sbjct: 698 -EMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKL 756
Query: 604 FFDEEEDHWKLHPITRLENQQMMKR 628
+++E KL + L +++ R
Sbjct: 757 KIEDQEREMKLEKLLLLNDKREQAR 781
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 283 bits (725), Expect = 3e-76
Identities = 175/388 (45%), Positives = 242/388 (62%), Gaps = 28/388 (7%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNP-----KGTAHEMPKTFTFD 60
S V+V VR RPMN +E + VV+++ G +V +P K + PK F FD
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFD 58
Query: 61 AVY----DWNAKQFELYDETFRPLVDSVL----QGFNGTIFAYGQTGTGKTYTMEGIRGD 112
+ + N ++ + F+ L + +L QG+N IFAYGQTG+GK+++M G
Sbjct: 59 YCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSM---MGH 115
Query: 113 PEKRGVIPNSFDHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLS-KDQTKRLELKER 169
E+ G+IP +F IS QN Q + V SY+EIY E++RDLL K + L+++E
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 170 PDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVG 229
G YV LS S ++IE +M+ GN++R+V ATNMNE SSRSHA+F I I +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 230 LD-GENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD---- 284
L G + +V K++LVDLAGSER +KTGA GERLKE + IN SL+ LG VIS+L D
Sbjct: 236 LQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAG 295
Query: 285 -GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNK 343
GKS +PYRDS LT LL+D+LGGN++T M+A + PA+ N EETL+TLRYA+RAK I N
Sbjct: 296 KGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNH 355
Query: 344 PRVNEDPKDALLREFQEEIARLKAQLEK 371
VNEDP ++RE +EE+ +L+ QL +
Sbjct: 356 AVVNEDPNAKVIRELREEVEKLREQLSQ 383
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 283 bits (725), Expect = 3e-76
Identities = 175/388 (45%), Positives = 242/388 (62%), Gaps = 28/388 (7%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNP-----KGTAHEMPKTFTFD 60
S V+V VR RPMN +E + VV+++ G +V +P K + PK F FD
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFD 58
Query: 61 AVY----DWNAKQFELYDETFRPLVDSVL----QGFNGTIFAYGQTGTGKTYTMEGIRGD 112
+ + N ++ + F+ L + +L QG+N IFAYGQTG+GK+++M G
Sbjct: 59 YCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSM---MGH 115
Query: 113 PEKRGVIPNSFDHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLS-KDQTKRLELKER 169
E+ G+IP +F IS QN Q + V SY+EIY E++RDLL K + L+++E
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 170 PDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVG 229
G YV LS S ++IE +M+ GN++R+V ATNMNE SSRSHA+F I I +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 230 LD-GENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD---- 284
L G + +V K++LVDLAGSER +KTGA GERLKE + IN SL+ LG VIS+L D
Sbjct: 236 LQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAG 295
Query: 285 -GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNK 343
GKS +PYRDS LT LL+D+LGGN++T M+A + PA+ N EETL+TLRYA+RAK I N
Sbjct: 296 KGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNH 355
Query: 344 PRVNEDPKDALLREFQEEIARLKAQLEK 371
VNEDP ++RE +EE+ +L+ QL +
Sbjct: 356 AVVNEDPNAKVIRELREEVEKLREQLSQ 383
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 283 bits (725), Expect = 3e-76
Identities = 175/388 (45%), Positives = 242/388 (62%), Gaps = 28/388 (7%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNP-----KGTAHEMPKTFTFD 60
S V+V VR RPMN +E + VV+++ G +V +P K + PK F FD
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFD 58
Query: 61 AVY----DWNAKQFELYDETFRPLVDSVL----QGFNGTIFAYGQTGTGKTYTMEGIRGD 112
+ + N ++ + F+ L + +L QG+N IFAYGQTG+GK+++M G
Sbjct: 59 YCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSM---MGH 115
Query: 113 PEKRGVIPNSFDHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLS-KDQTKRLELKER 169
E+ G+IP +F IS QN Q + V SY+EIY E++RDLL K + L+++E
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 170 PDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVG 229
G YV LS S ++IE +M+ GN++R+V ATNMNE SSRSHA+F I I +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 230 LD-GENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD---- 284
L G + +V K++LVDLAGSER +KTGA GERLKE + IN SL+ LG VIS+L D
Sbjct: 236 LQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAG 295
Query: 285 -GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNK 343
GKS +PYRDS LT LL+D+LGGN++T M+A + PA+ N EETL+TLRYA+RAK I N
Sbjct: 296 KGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNH 355
Query: 344 PRVNEDPKDALLREFQEEIARLKAQLEK 371
VNEDP ++RE +EE+ +L+ QL +
Sbjct: 356 AVVNEDPNAKVIRELREEVEKLREQLSQ 383
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 283 bits (725), Expect = 3e-76
Identities = 175/388 (45%), Positives = 242/388 (62%), Gaps = 28/388 (7%)
Query: 6 SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNP-----KGTAHEMPKTFTFD 60
S V+V VR RPMN +E + VV+++ G +V +P K + PK F FD
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFD 58
Query: 61 AVY----DWNAKQFELYDETFRPLVDSVL----QGFNGTIFAYGQTGTGKTYTMEGIRGD 112
+ + N ++ + F+ L + +L QG+N IFAYGQTG+GK+++M G
Sbjct: 59 YCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSM---MGH 115
Query: 113 PEKRGVIPNSFDHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLS-KDQTKRLELKER 169
E+ G+IP +F IS QN Q + V SY+EIY E++RDLL K + L+++E
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREH 175
Query: 170 PDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVG 229
G YV LS S ++IE +M+ GN++R+V ATNMNE SSRSHA+F I I +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 230 LD-GENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD---- 284
L G + +V K++LVDLAGSER +KTGA GERLKE + IN SL+ LG VIS+L D
Sbjct: 236 LQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAG 295
Query: 285 -GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNK 343
GKS +PYRDS LT LL+D+LGGN++T M+A + PA+ N EETL+TLRYA+RAK I N
Sbjct: 296 KGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNH 355
Query: 344 PRVNEDPKDALLREFQEEIARLKAQLEK 371
VNEDP ++RE +EE+ +L+ QL +
Sbjct: 356 AVVNEDPNAKVIRELREEVEKLREQLSQ 383
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 283 bits (725), Expect = 3e-76
Identities = 210/604 (34%), Positives = 313/604 (51%), Gaps = 62/604 (10%)
Query: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
VRV +RCRP+ KE + + QV V GT K+FT+D V+D + +Q
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVV----GT----DKSFTYDFVFDPSTEQ 61
Query: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR----GVIPNSFDH 125
E+++ PL+ V +G+N T+ AYGQTG+GKTY+M G ++ GVIP
Sbjct: 62 EEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQL 121
Query: 126 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTK-RLELKERPDTGVYVKDLSSFVT 184
+F I + + ++ ++ SYLEIY EEI DLL + K ++ ++E P G+ + L+
Sbjct: 122 LFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
Query: 185 KSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLV 244
+ + GN +R+V +T MN SSRSHAIF I++E + D + R KL+LV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS-DKNSSFR-SKLHLV 239
Query: 245 DLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKST-HIPYRDSKLTRLLQD 303
DLAGSERQ KT A+G+RLKE IN L LGNVISAL D K +PYRDSKLTRLLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299
Query: 304 SLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIA 363
SLGGN+ T+M+A V PA N+EETL TLRYA+RA+ IKNKP VN DP+ A L ++++
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQ 359
Query: 364 RLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEI 423
+L+ L + GG G E E + E K+ E+ EKL
Sbjct: 360 QLQVLL------------LQAHGGTLPGSITVEPSENLQSLME---KNQSLVEENEKL-- 402
Query: 424 EKRAIVEDHSLVAEEKMRLL------KEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVG 477
R + E A+ R++ ++ K+E+LR+ L ++ +E + L
Sbjct: 403 -SRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKE 461
Query: 478 GKNIVDHTNEQQKILEQKRQEIA----------EQKRREREIQQQMESRDEETLELKETY 527
I+ N QQ I + + +A EQ+ + + S D T +
Sbjct: 462 NVEII--CNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQ 519
Query: 528 SSLQQEV----------DIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT 577
+ + +E+ + +K+ + S+LQ ++ + D +E E L++ + EL
Sbjct: 520 AQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELV 579
Query: 578 RELK 581
EL+
Sbjct: 580 LELQ 583
Score = 51.6 bits (122), Expect = 3e-06
Identities = 75/360 (20%), Positives = 153/360 (42%), Gaps = 34/360 (9%)
Query: 258 QGERLKEATKINLSLSALGNVISALVDGKSTHIP----YRDSKLTRLLQDSLGGNAKTVM 313
Q + KE ++N +L+ + + S P Y+D+ L+ K +
Sbjct: 519 QAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEEL 578
Query: 314 VANVGPASYNVEETLTTLRYANRAKNIKN-----KPRVNEDPKDALLREFQEE-IARLKA 367
V + A + + + R R + ++ K ++NE K L+E E +++L
Sbjct: 579 VLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQ 638
Query: 368 QLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYW-----REQQEKLE 422
++ R + + +E ++++++ +E D K Y R Q++
Sbjct: 639 EIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSN 698
Query: 423 IEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLG--AKIK---AMESKLLVG 477
+ +R E + A ++++ +K++++ D R+E + M G A++K E +++V
Sbjct: 699 VLRRKTEE--AAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVS 756
Query: 478 GKNIVDHTN---EQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEV 534
+ H N E +KIL Q ++ E+K ++ R T L E + +
Sbjct: 757 TEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRR---TFSLTEVRGQVSESE 813
Query: 535 DIKTKKLKKLFSKLQAVKAEIHDLQ------EEHIKERQELEQTQNELTRELKLKHLIIE 588
D TK+++ L ++++ A+I DLQ E + +Q E L + LK+LI E
Sbjct: 814 DSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGE 873
Score = 40.0 bits (92), Expect = 0.008
Identities = 54/262 (20%), Positives = 115/262 (43%), Gaps = 37/262 (14%)
Query: 340 IKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEE 399
+K + R + L R FQ++ L+ + E+ + ++ ++ ++ +E +
Sbjct: 675 LKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSR 734
Query: 400 GEEGEEE------GDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMED- 452
G EG G++ + ++ K + ++ED ++A++ +L KEK++ E+
Sbjct: 735 GMEGTAARVKNWLGNEIEVMVSTEEAKRHLND--LLEDRKILAQDVAQL-KEKKESGENP 791
Query: 453 ---LRRE-----------KDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQE 498
LRR ++ + + +I+++E+++ I D QQK+L+ + ++
Sbjct: 792 PPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADL---QQKLLDAESED 848
Query: 499 IAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDL 558
K+R I +E++ + E SS Q + KL S L+ K D+
Sbjct: 849 --RPKQRWENIATILEAKCALKYLIGELVSSKIQ--------VSKLESSLKQSKTSCADM 898
Query: 559 QEEHIKERQELEQTQNELTREL 580
Q+ +ER + + EL EL
Sbjct: 899 QKMLFEERNHFAEIETELQAEL 920
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 282 bits (722), Expect = 7e-76
Identities = 203/578 (35%), Positives = 305/578 (52%), Gaps = 37/578 (6%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKG--TAHEMPKTFTFDAVYDWN 66
+++V+ R RP+N E V G + +G T K + FD V+ +
Sbjct: 8 NIKVMCRFRPLNESE------------VNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSS 55
Query: 67 AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHI 126
Q ++Y++ + +V VL+G+NGTIFAYGQT +GKT+TMEG DPE G+IP I
Sbjct: 56 TSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDI 115
Query: 127 FTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTK 185
F +I S +N ++ ++ SY EIY ++IRDLL +T L + E + YVK +
Sbjct: 116 FNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKT-NLSVHEDKNRVPYVKGCTERFVC 174
Query: 186 SVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVD 245
S E+ ++ G NR V TNMNEHSSRSH+IF+I ++ + + GKL LVD
Sbjct: 175 SPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK---LSGKLYLVD 231
Query: 246 LAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSL 305
LAGSE+ +KTGA+G L EA IN SLSALGNVISAL +G ST++PYRDSK+TR+LQDSL
Sbjct: 232 LAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-STYVPYRDSKMTRILQDSL 290
Query: 306 GGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVN-EDPKDALLREFQEEIAR 364
GGN +T +V P+SYN ET +TL + RAK IKN VN E + +++++E +
Sbjct: 291 GGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKE--K 348
Query: 365 LKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIE 424
K ++ + +I + R G + E+ ++E E DKD + I
Sbjct: 349 EKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIG 408
Query: 425 KRAIVED--HSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIV 482
D EE +L K+ + K E++ ++ E L ++ E +LL +
Sbjct: 409 VIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQE-ELLASTRRDQ 467
Query: 483 DHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLK 542
D+ Q L + + E K +E+ Q +E EL Y QEV+ KTK+ +
Sbjct: 468 DN---MQAELNRLQAENDASKEEVKEVLQALE-------ELAVNYDQKSQEVEDKTKEYE 517
Query: 543 KLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTREL 580
L +L A + + E +++ +E+ Q + E+
Sbjct: 518 LLSDELNQKSATLASIDAE-LQKLKEMTNHQKKRAAEM 554
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/272 (18%), Positives = 116/272 (42%), Gaps = 35/272 (12%)
Query: 338 KNIKNKPRVNEDPKDALLREFQEEIARLKAQ-----LEKRSIGRRKRREKRREGGGSGGG 392
+N++ K R E+ DAL EE+ +L+AQ +EK + + + + ++
Sbjct: 651 QNVEQKKRQLEESVDAL----SEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQ 706
Query: 393 GEEEEEEGE------EGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEK 446
E + + E E + D + Q+ + ++R VE L A ++ EK
Sbjct: 707 SHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQ-----EK 761
Query: 447 EKKMEDLRREKDAAEMLGAKIKAMES-------------KLLVGGKNIVDHTNEQQKILE 493
+K+ +L +D E +K +E KL V +++ + +I
Sbjct: 762 SRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFV--QDLATRVKKSAEIDS 819
Query: 494 QKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKA 553
A QK++ ++ +E + +L + L+ E+ K+L+ +++A+++
Sbjct: 820 DDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALES 879
Query: 554 EIHDLQEEHIKERQELEQTQNELTRELKLKHL 585
+ + +E ++R+ +Q + + ++ K++
Sbjct: 880 ALKEAKENASRDRKRYQQEVDRIKEAVRSKNM 911
Score = 40.0 bits (92), Expect = 0.008
Identities = 52/269 (19%), Positives = 117/269 (43%), Gaps = 33/269 (12%)
Query: 456 EKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMES 515
E A + +K+K+ ++ K + E K +E+ +E+A + R + + +++S
Sbjct: 586 EFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKS 645
Query: 516 RDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNE 575
E +++ L++ VD +++L +L + ++H++++EH+ + QT NE
Sbjct: 646 LTEYLQNVEQKKRQLEESVDALSEELVQL-----RAQEKVHEMEKEHLNK----VQTANE 696
Query: 576 LTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGY 635
+K + + E + + DE E KL + +NQ+MM +
Sbjct: 697 ------VKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMM------LEQ 744
Query: 636 KRPLSQHARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEG--PAIAPKVQA------- 686
+R +H ++ + ++R E V+ D + +D +G +A ++Q
Sbjct: 745 ERLRVEHEKLKATDQEKSRKLHELTVM--QDRREQARQDLKGLEETVAKELQTLHNLRKL 802
Query: 687 -ALDAALQDEDEIQVDASSFESTANKKSK 714
D A + + ++D+ +A +K K
Sbjct: 803 FVQDLATRVKKSAEIDSDDTGGSAAQKQK 831
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 282 bits (721), Expect = 9e-76
Identities = 168/392 (42%), Positives = 238/392 (60%), Gaps = 32/392 (8%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWN-- 66
SV+V VR RP N +E S D + + ++ NPK E PK+F+FD Y W+
Sbjct: 5 SVKVAVRVRPFNSREM--SRDSKCIIQMSGSTTTIVNPK-QPKETPKSFSFDYSY-WSHT 60
Query: 67 -------AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVI 119
A Q ++Y + ++ +G+N IFAYGQTG GK+YTM G + + +++G+I
Sbjct: 61 SPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMG-KQEKDQQGII 119
Query: 120 PNSFDHIFTHIS--RSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVK 177
P + +F+ I+ + N Y V SY+EIY E +RDLL+ L ++E P G YV+
Sbjct: 120 PQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVE 179
Query: 178 DLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHI- 236
DLS S +I+ +M+ GN+ R+V ATNMNE SSRSHA+F I ++ D E +I
Sbjct: 180 DLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIF--TQKRHDAETNIT 237
Query: 237 --RVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD---------- 284
+V K++LVDLAGSER TGA+G RLKE IN SL+ LG VISAL +
Sbjct: 238 TEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKK 297
Query: 285 -GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNK 343
K+ IPYRDS LT LL+++LGGN++T MVA + PA N +ETL+TLRYA+RAK I+
Sbjct: 298 KKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCN 357
Query: 344 PRVNEDPKDALLREFQEEIARLKAQLEKRSIG 375
+NEDP + L+RE ++E+ RL+ L + +G
Sbjct: 358 AVINEDPNNKLIRELKDEVTRLRDLLYAQGLG 389
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 281 bits (720), Expect = 1e-75
Identities = 216/672 (32%), Positives = 342/672 (50%), Gaps = 63/672 (9%)
Query: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
VRV +RCRP+ KE + + QV V GT K+FT+D V+D +Q
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVV----GT----DKSFTYDFVFDPCTEQ 61
Query: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR----GVIPNSFDH 125
E++++ PL+ + +G+N T+ AYGQTG+GKTY+M G ++ G+IP
Sbjct: 62 EEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQL 121
Query: 126 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTK-RLELKERPDTGVYVKDLSSFVT 184
+F I + + ++ ++ SYLEIY EEI DLL + K ++ ++E P G+ + L+
Sbjct: 122 LFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
Query: 185 KSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLV 244
+ + GN +R+V +T MN SSRSHAIF I+IE + +N KL+LV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS--DKNCSFRSKLHLV 239
Query: 245 DLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKS-THIPYRDSKLTRLLQD 303
DLAGSERQ KT A+G+RLKE IN L LGNVISAL D K + +PYRDSKLTRLLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299
Query: 304 SLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIA 363
SLGGN+ T+M+A V PA N+EETL+TLRYA+RA+ IKNKP VN DP A L ++++
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQ 359
Query: 364 RLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEI 423
+L+ L + GG G E E + E K+ E+ EKL
Sbjct: 360 QLQVLL------------LQAHGGTLPGSINAEPSENLQSLME---KNQSLVEENEKL-- 402
Query: 424 EKRAIVEDHSLVAEEKMRLL------KEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVG 477
R + + A+ R++ ++ K+E+LR+ L ++ +E + L
Sbjct: 403 -SRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKE 461
Query: 478 GKNIVDHTNEQQKILEQKRQEIA----------EQKRREREIQQQMESRDEETLELKETY 527
I+ N QQ I + + +A E++ + + S D T +
Sbjct: 462 NVEII--CNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQ 519
Query: 528 SSLQQEV----------DIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT 577
+ + +EV + +K+ + ++LQ ++ + D + E L++ + EL
Sbjct: 520 AQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELV 579
Query: 578 RELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITR-LENQQMMKRPVSAVGYK 636
REL+ + E + K++ + KL+ ++ L+ ++ +R VS + +
Sbjct: 580 RELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQE 639
Query: 637 RPLSQHARMSMM 648
+ ++ R+ +M
Sbjct: 640 IWMMKNQRVQLM 651
Score = 46.2 bits (108), Expect = 1e-04
Identities = 54/264 (20%), Positives = 121/264 (45%), Gaps = 21/264 (7%)
Query: 343 KPRVNEDPKDALLREFQEE-IARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGE 401
K ++NE K L+E E +++L ++ R + + +E ++++++
Sbjct: 613 KKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEV 672
Query: 402 EGEEEGDDKDDYWREQQEKLEIEKRAIVE---DHSLVAEEKMRLLKEKEKKMEDLRREKD 458
+E D K Y + E+ ++ +++ + + A ++++ +K++++ D R+E
Sbjct: 673 IQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQ 732
Query: 459 A--AEMLGAKIK---AMESKLLVGGKNIVDHTN---EQQKILEQKRQEIAEQKRREREIQ 510
+ E + A+++ E +++V + H N E +KIL Q ++ E+K
Sbjct: 733 SHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPP 792
Query: 511 QQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQ------EEHIK 564
++ T L E + + + D TK+++ L ++++ A+I DLQ E +
Sbjct: 793 PKLRKC---TFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDR 849
Query: 565 ERQELEQTQNELTRELKLKHLIIE 588
+Q E L + LK+LI E
Sbjct: 850 PKQCWENIATILEAKCALKYLIGE 873
Score = 33.5 bits (75), Expect = 0.74
Identities = 34/212 (16%), Positives = 96/212 (45%), Gaps = 31/212 (14%)
Query: 416 EQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRRE----------KDAAEM--- 462
E +L+ K+ + + + ++E + +LL+E E ++ DL+++ K++ E
Sbjct: 577 ELVRELQTAKKNV--NQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVS 634
Query: 463 -LGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQM-------- 513
L +I M+++ + + + + + ++ ++K +E+ + K R+R+ Q ++
Sbjct: 635 KLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQ 694
Query: 514 -------ESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKER 566
+E K +LQ++ ++ K+ + + + A + + I+
Sbjct: 695 KQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVM 754
Query: 567 QELEQTQNELTRELKLKHLIIENFIPLEEKSK 598
E+ + L L+ + ++ ++ + L+EK +
Sbjct: 755 VSTEEAKRHLNDLLEDRKILAQDVVQLKEKKE 786
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 269 bits (688), Expect = 6e-72
Identities = 211/718 (29%), Positives = 342/718 (47%), Gaps = 103/718 (14%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAK 68
SVRV VR RP KEK V QV + K FTFD V+D +++
Sbjct: 9 SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKA--------FTFDYVFDIDSQ 60
Query: 69 QFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTME---GIRGDPEKRGVIPNSFDH 125
Q ++Y + L++ +G+N T+FAYGQTG GKTYTM + E+ G+I + H
Sbjct: 61 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 120
Query: 126 IFTHISRSQN---------QQYLVRASYLEIYQEEI-------RDLLSKDQTKRLELKER 169
+F I ++ + V A +LE+Y EE+ RD+ +K + + + E
Sbjct: 121 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 180
Query: 170 PDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVI----TIEC 225
G+Y +++ + E+ + +G +R+ +T MN SSRSHAIF I T C
Sbjct: 181 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240
Query: 226 SEVGLDGENHIRV--------------GKLNLVDLAGSERQAKTGAQGERLKEATKINLS 271
++ D ++ K + VDLAGSER +TGA GER KE IN
Sbjct: 241 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 300
Query: 272 LSALGNVISALVDG--KSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLT 329
L ALGNVISAL D ++TH+PYRDSKLTRLLQDSLGGN++T+M+A V P+ + ETL
Sbjct: 301 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 360
Query: 330 TLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS 389
TL+YANRA+NIKNK VN+D + + EI RL+ +L + G+R E+ E
Sbjct: 361 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVE---- 416
Query: 390 GGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVE------DHSLVA-----EE 438
+ E + E ++ + QE ++ + I + +H L EE
Sbjct: 417 --SINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEE 474
Query: 439 KMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQ- 497
++ K++EDLR + +E + ++ ++ + IL ++
Sbjct: 475 ISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKET 534
Query: 498 -EIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIH 556
EI + +++ E ++ E R ++++ KE + QE KK +K S+ + + E+
Sbjct: 535 IEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQE-----KKEEKGVSERENNELEVE 589
Query: 557 DLQE--EHIKERQELEQTQNE--------------------------LTRELKLKHLIIE 588
+ QE +H E +E E+ +++ +T E+ +K +I+
Sbjct: 590 ESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLID 649
Query: 589 NFIPLEEKSKIMNRAFFDEEEDHWKLHPI--TRLENQQMMKRPVSAVGYKRPLSQHAR 644
+++ + + + + EE+ H I T+LE Q+++ S Y ++ R
Sbjct: 650 ELENSQKRLQTLKKQY--EEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVR 705
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/261 (22%), Positives = 114/261 (43%), Gaps = 22/261 (8%)
Query: 330 TLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS 389
T+ + AK K + E K + ++ + + E++ + R+ E E
Sbjct: 534 TIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQE 593
Query: 390 GGGGEEEEEEGEEGEEE---GDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEK 446
E+EEEE EE E++ G+ D+ E EK + A + + + K +L+ E
Sbjct: 594 VSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQ--ADLANITCEIAIKQKLIDEL 651
Query: 447 EKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKIL------EQKRQEIA 500
E + L+ K K E KL++ I D E+ ++L E +E A
Sbjct: 652 ENSQKRLQTLK----------KQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKA 701
Query: 501 EQKRREREIQQQMESRDEETLE-LKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQ 559
++ R E E + Q +++ + L+ ++ ++ L + K+LKKL + +K L
Sbjct: 702 KKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLM 761
Query: 560 EEHIKERQELEQTQNELTREL 580
++ +E+++ T++ RE+
Sbjct: 762 KQMKEEQEKARLTESRRNREI 782
Score = 33.9 bits (76), Expect = 0.57
Identities = 45/218 (20%), Positives = 99/218 (45%), Gaps = 35/218 (16%)
Query: 355 LREFQEEIARLKAQLEKRSIG-----RRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDD 409
L Q+ + LK Q E++ + R + E+ + G EE+ ++ E +
Sbjct: 651 LENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEK 710
Query: 410 KDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRR-EKDAAEMLGAKIK 468
K ++ ++L+ ++ E RLLK + + + L++ ++D EM K++
Sbjct: 711 KLQAMNKELQRLQAAQK-----------EHARLLKNQSQYEKQLKKLQQDVMEMKKTKVR 759
Query: 469 AMESKLLVGGKNIVDHTNEQQKILEQKR-QEIAEQKRREREIQQQM-----ESRDEETLE 522
M+ + E+ ++ E +R +EIA+ K+ +R+ Q+ + R++E +
Sbjct: 760 LMKQ---------MKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVL 810
Query: 523 LKET--YSSLQQEV-DIKTKKLKKLFSKLQAVKAEIHD 557
++T ++L+++V + K K+ KL + A D
Sbjct: 811 RRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQD 848
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 268 bits (685), Expect = 1e-71
Identities = 179/485 (36%), Positives = 277/485 (57%), Gaps = 35/485 (7%)
Query: 3 KLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPK-----GTAHEMPKTF 57
K+++S+ V V VR RP +EK +VV + K +++V++P +++ +
Sbjct: 353 KVENSQ-VTVAVRVRPFTKREKIEKASQVVFMSGK--EITVEHPDTKQVYNFIYDV-SFW 408
Query: 58 TFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRG 117
+FD + A Q +Y++ PL++ +GFN +FAYGQTG+GK+YTM G +P G
Sbjct: 409 SFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---G 465
Query: 118 VIPNSFDHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLL-SKDQTKR----LELKERP 170
+IP + +F+ ++R Q Q+ Y + S+ E+Y E+I DLL KD+ + L ++E P
Sbjct: 466 IIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHP 525
Query: 171 DTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVG- 229
G YV+ LS + S +I+ + +GN+ R+ AT MN+ SSRSH++F + + ++
Sbjct: 526 VYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEF 585
Query: 230 LDGENHIR--VGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISAL---VD 284
++GE H ++NL+DLAGSER + G+RLKE IN SL LG VISAL +
Sbjct: 586 VEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQAN 645
Query: 285 GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKP 344
+S IPYR+S LT LL++SLGGN+KT M+A + PA+ N+EETL+TLRYAN+A+ I N
Sbjct: 646 QRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIA 705
Query: 345 RVNEDPKDALLREFQEEIARLK-AQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEG 403
+VNED L+RE + EIA+LK AQ R+I + R R+E ++E + E
Sbjct: 706 KVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEM 765
Query: 404 EEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEML 463
+ W+E+ E + EKR + E L M + + +L + +EML
Sbjct: 766 QR-------VWKEKFE--QAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEML 816
Query: 464 GAKIK 468
IK
Sbjct: 817 LYMIK 821
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/150 (26%), Positives = 74/150 (49%), Gaps = 22/150 (14%)
Query: 434 LVAEEKMRLLKEKEKKMEDLRREKDAAEM-LGAKIKAMESKLLVGGKNIVDHTNEQQKIL 492
L AE K LK KE+ M+ ++ K+ A+ L ++ A ESK+ K L
Sbjct: 939 LEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKI---------------KAL 983
Query: 493 EQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVK 552
E + +E +++K+ + EI Q + E EL++ L+QE+ + K+L+ + A K
Sbjct: 984 EAELREESQRKKMQ-EINNQKANHKIE--ELEKAKQHLEQEIYVNKKRLE---METLATK 1037
Query: 553 AEIHDLQEEHIKERQELEQTQNELTRELKL 582
+ D H + + LE + ++ +E+++
Sbjct: 1038 QALEDHSIRHARILEALETEKQKIAKEVQI 1067
Score = 37.0 bits (84), Expect = 0.067
Identities = 45/208 (21%), Positives = 97/208 (46%), Gaps = 24/208 (11%)
Query: 346 VNEDPKD---ALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEE 402
++E PKD A + ++L+A++++ + K +E+ +G ++E ++
Sbjct: 917 ISEGPKDFEFAKNELLMAQRSQLEAEIKEAQL---KAKEEMMQGIQIAKEMAQQELSSQK 973
Query: 403 GEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEM 462
E K E + + E +++ + E ++ A K ++E EK + L +E
Sbjct: 974 AAYESKIKA---LEAELREESQRKKMQEINNQKANHK---IEELEKAKQHLEQE------ 1021
Query: 463 LGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLE 522
+ K +E + L + + DH+ +ILE E ++ +E +I QQ + ++T
Sbjct: 1022 IYVNKKRLEMETLATKQALEDHSIRHARILEALETE-KQKIAKEVQILQQNRNNRDKTFT 1080
Query: 523 LKETYSSLQ-----QEVDIKTKKLKKLF 545
++ T+SS++ QE + + KLK +
Sbjct: 1081 VQTTWSSMKLSMMIQEANAISSKLKTYY 1108
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 264 bits (674), Expect = 3e-70
Identities = 205/595 (34%), Positives = 318/595 (53%), Gaps = 67/595 (11%)
Query: 10 VRVVVRCRPMNGKEKAASYDKVVDV--------DVKLGQVSVKNPKGTAHE-------MP 54
++VVVR RP N KEKAA + KVV V D K +VS + K T ++
Sbjct: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
Query: 55 KTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPE 114
F FDAV+D + Q E+++ T +P++ S L G+N T+ AYG TG GKT+TM G +P
Sbjct: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
Query: 115 KRGVIPNSFDHIFTHISRSQNQQYLVRA-SYLEIYQEEIRDLLSKDQTKRLELKERPDTG 173
GV+ + H++ + + ++ A SYLE+Y E+IRDLL L ++E G
Sbjct: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDTQKG 186
Query: 174 VYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGE 233
V V L+ KS +EI H+++ GN+NR+ T+MN SSRSHA+F I + +
Sbjct: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
Query: 234 NHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIP 291
++R+ K++L+DLAGSER + +GA+G R E T IN SL ALGNVI+AL D K+ HIP
Sbjct: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
Query: 292 YRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPK 351
YR+SKLTRLL+DSLGGN +T+M+A V P+S ++T TL+YANRAK+IK+ + N
Sbjct: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNV 366
Query: 352 DALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKD 411
+ + ++ + KA++ +EK + EE + E D
Sbjct: 367 NNHITQYVKICNEQKAEI-------LLLKEKLK-----------AYEEQKAFTNENDQAK 408
Query: 412 DYWREQQEKLEIEK-----RAIVEDHSLVAEEKMR---LLKEKEKKMEDLRREKDAAEML 463
QEK EIE+ + ++ + +E ++ LLKE E K ++ EM+
Sbjct: 409 LMISNPQEK-EIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMM 467
Query: 464 GAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMES-----RDE 518
++ K ++ GK DH + +L+ +R + +KRRE E++Q E+ R E
Sbjct: 468 CSEDKVEKAT----GKR--DH---RLAMLKTRRSYL--EKRREEELKQFDENTNWLHRVE 516
Query: 519 ETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQ 573
+ + L + +E+ K L + + +KA+I + + + Q+ QT+
Sbjct: 517 KEMGLLSQNGHIPKELK-KDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTE 570
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 262 bits (669), Expect = 1e-69
Identities = 192/582 (32%), Positives = 291/582 (50%), Gaps = 71/582 (12%)
Query: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
V+V VR RP KEK + V G+ V K K FT+D V+D + Q
Sbjct: 9 VKVAVRIRPQLSKEKIEGCH--ICTSVTPGEPQVLLGKD------KAFTYDFVFDLDTWQ 60
Query: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTME---GIRGDPEKRGVIPNSFDHI 126
++Y L++ +G+N T+ AYGQTG GKTYTM + E++G+IP + H+
Sbjct: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
Query: 127 FTHIS----RSQNQ-----QYLVRASYLEIYQEEIRDLL-------SKDQTKRLELKERP 170
F I+ R+Q Q ++ V A +LE+Y EEI DL ++ + +++ E
Sbjct: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
Query: 171 DTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITI----ECS 226
+ G+Y ++S + S +E+ + G +R+ +T MN SSRSHAIF I + C+
Sbjct: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
Query: 227 EVGL---------DG-----ENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSL 272
+ L DG E K + VDLAGSER +TGA GER KE IN L
Sbjct: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
Query: 273 SALGNVISALVDG--KSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTT 330
ALGNVISAL D K H+PYRDSKLTRLLQDSLGGN++T+M+A V P+ + ETL T
Sbjct: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
Query: 331 LRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGG-- 388
L+YANRA+NIKNK VN+D + + EIARL+ +L + G+R E EG
Sbjct: 361 LKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDL 420
Query: 389 ---------SGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKR--------AIVED 431
G + +E + +++ Q+ L + K A++++
Sbjct: 421 FRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQN 480
Query: 432 HSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKI 491
+ EE L E E E LRR A G + + ++
Sbjct: 481 YIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV 540
Query: 492 LEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQE 533
+ + +Q++ ++ +++E++Q+ +S ++E + + + LQQE
Sbjct: 541 IRRAKQDL--ERLKKKEVRQRRKSPEKEAFKKR---AKLQQE 577
Score = 53.5 bits (127), Expect = 7e-07
Identities = 59/265 (22%), Positives = 122/265 (46%), Gaps = 27/265 (10%)
Query: 337 AKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEE 396
A ++++ V K L R ++E+ + + EK + +R + ++ EEE
Sbjct: 531 ASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEE 590
Query: 397 EEEGEEG---EEEG--DDKDDYWREQQ--------EKLEIEKRAIVEDHSLVAEEKMRLL 443
EEE +E EEEG D+ +D E+ E+ E+ +A + D + E K +L+
Sbjct: 591 EEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLI 650
Query: 444 KEKEKKMEDLRREKDAAEMLGAKIKAMESKL---LVGGKNIVDHTNEQQKILEQKRQEI- 499
E E L+ K E K+ +++K+ + ++ + + + E+K +I
Sbjct: 651 DELENSQRRLQTLKHQYE---EKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIK 707
Query: 500 AEQKRREREIQ---QQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIH 556
A+ ++R RE+ Q++++ +E L + S ++E+ KKL+ ++++ K +
Sbjct: 708 ADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYEREL----KKLQAEVAEMKKAKVALM 763
Query: 557 DLQEEHIKERQELEQTQNELTRELK 581
E + R+ +E +N +LK
Sbjct: 764 KQMREEQQRRRLVETKRNREIAQLK 788
Score = 51.2 bits (121), Expect = 3e-06
Identities = 58/298 (19%), Positives = 138/298 (46%), Gaps = 27/298 (9%)
Query: 344 PRVNEDPKDALLREFQEEIARLKA-QLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEE 402
P + + ++R ++++ RLK ++ +R K K+R E +E E EE
Sbjct: 530 PASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEE 589
Query: 403 GEEEGDD---KDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDA 459
EEE D+ +++ RE +++ + ++V+ S E+++ + + DL E +
Sbjct: 590 EEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNF----QADLADLTCEIEI 645
Query: 460 AEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEE 519
+ L +++ + +L + H E++ IL Q K R+ ++++ ++
Sbjct: 646 KQKLIDELENSQRRL-----QTLKHQYEEKLILLQ-------NKIRDTQLERDRVLQNLS 693
Query: 520 TLE--LKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT 577
T+E +E + ++ + + + +++ + KLQA + E L + + +EL++ Q E+
Sbjct: 694 TMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVA 753
Query: 578 RELKLKHLIIENFIPLEEKSKIM----NRAFFD-EEEDHWKLHPITRLENQQMMKRPV 630
K K +++ +++ +++ NR ++E + I LE+Q+ + V
Sbjct: 754 EMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMV 811
Score = 35.0 bits (79), Expect = 0.25
Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 12/148 (8%)
Query: 408 DDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRR-EKDAAEMLGAK 466
++K + + EK E ++ +E RLLK + + +L++ + + AEM AK
Sbjct: 700 EEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAK 759
Query: 467 IKAMESKLLVGGKNIVDHTNEQQKILEQKR-QEIAEQKRREREIQQQMESRDEETLELKE 525
+ M+ + ++++++E KR +EIA+ K+ +R + Q+ + + + + +
Sbjct: 760 VALMKQ---------MREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEM 810
Query: 526 TYSSLQQEVDIKTKKLKKLFSKLQAVKA 553
QEV ++L K S+ A +A
Sbjct: 811 VLRRKTQEVS-ALRRLAKPMSERVAGRA 837
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 254 bits (650), Expect = 2e-67
Identities = 184/526 (34%), Positives = 270/526 (51%), Gaps = 32/526 (6%)
Query: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
VRV +R RP+ KE + + V+ LG+V++ + F F V +A Q
Sbjct: 16 VRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRH--------FGFHVVLAEDAGQ 67
Query: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDP---EKRGVIPNSFDHI 126
+Y +PL+++ +GFN T+FAYGQTG+GKTYTM +++G++P +
Sbjct: 68 EAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEA 127
Query: 127 FTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKR-LELKERPDTGVYVKDLSSFVTK 185
F I + LV SYLE+Y+EE RDLL R ++L+E V + + +
Sbjct: 128 FKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
Query: 186 SVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIEC-----SEVGLDGENHIRVGK 240
+ E+ ++ +GN R GAT++N SSRSH +F +T+E S + + V K
Sbjct: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
Query: 241 LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIPYRDSKLT 298
+ VDLAGSER KTG+ GERLKE+ +IN SL ALGNVISAL D + +HIPYRDSK+T
Sbjct: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
Query: 299 RLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREF 358
R+L+DSLGGNAKTVM+A V P+S + +ETL TL YA+RA+NI+N+ VN P+ R
Sbjct: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAE--RPP 365
Query: 359 QEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEG--DDKDDYWRE 416
+E + + RS R R +R G + E D RE
Sbjct: 366 EETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAYSLLRE 425
Query: 417 QQEKLEIEKRAI--VEDHSLVAEEKMRLLKE---KEKKMEDLRREKDAAEMLGAKIKAME 471
Q + + A V D E + L + +E E AA+ G + +
Sbjct: 426 LQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGRKEDEG 485
Query: 472 SKLLVGGKNIVDHTNEQQK----ILEQKRQEIAEQKRREREIQQQM 513
++ L+ +N V E+ + LE ++ Q R RE Q++M
Sbjct: 486 AQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEM 531
Score = 46.6 bits (109), Expect = 8e-05
Identities = 74/368 (20%), Positives = 158/368 (42%), Gaps = 73/368 (19%)
Query: 355 LREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYW 414
+RE ++E +++A+L + G+R+ RE EG+E ++ G+
Sbjct: 745 IRELEQEAEQVRAELSE---GQRQLREL----------------EGKELQDAGE------ 779
Query: 415 REQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKL 474
+ +L+ +R + A+ ++++LKEK K A E L + A K
Sbjct: 780 ---RSRLQEFRRRVA-----AAQSQVQVLKEK----------KQATERL-VSLSAQSEKR 820
Query: 475 LVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEV 534
L + V +QQ L+++ +E EQKRR ++ +M R EL+ + Q+ +
Sbjct: 821 LQELERNVQLMRQQQGQLQRRLREETEQKRR---LEAEMSKRQHRVKELELKHEQQQKIL 877
Query: 535 DIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLE 594
IKT+++ + Q + + ++++Q++E+ + L +E+
Sbjct: 878 KIKTEEI----AAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEM-------------- 919
Query: 595 EKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEAR 654
EK RA + E+ K I L ++ + + + + KR S A ++R +R
Sbjct: 920 EKVLQQRRALEELGEELHKREAI--LAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSR 977
Query: 655 YRAENIVLLELDMPSRTTRDYEGPAIA-PKVQAALDAALQDEDEIQVDASSFESTANKKS 713
+ LE ++ ++ + +G A + +++ +D+ Q++D + + + S
Sbjct: 978 -----LEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGS 1032
Query: 714 KARPKSGR 721
P+ R
Sbjct: 1033 LLSPEEER 1040
Score = 35.4 bits (80), Expect = 0.19
Identities = 61/296 (20%), Positives = 115/296 (38%), Gaps = 31/296 (10%)
Query: 372 RSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVED 431
R G E R G GS EEEEEE EE + + R + +RA
Sbjct: 602 REAGAELLTEVNRLGSGSSAASEEEEEE-----EEPPRRTLHLRRNRIS-NCSQRAGARP 655
Query: 432 HSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKI 491
SL E+K +L E+ A + G++ SK V + + T + ++
Sbjct: 656 GSL-----------PERKGPELCLEELDAAIPGSRAVG-GSKARVQARQVPPATASEWRL 703
Query: 492 LE--QKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQ 549
+ QK +E+A R + E+ ++ + L +S +E++ + ++++ S+ Q
Sbjct: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
Query: 550 AVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEE 609
E+ + + ER L++ + + + L+EK + R +
Sbjct: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQV-------LKEKKQATERLVSLSAQ 816
Query: 610 DHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLEL 665
+L + R N Q+M++ + +R L + + E R + LEL
Sbjct: 817 SEKRLQELER--NVQLMRQQQGQL--QRRLREETEQKRRLEAEMSKRQHRVKELEL 868
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 249 bits (635), Expect = 9e-66
Identities = 157/400 (39%), Positives = 235/400 (58%), Gaps = 32/400 (8%)
Query: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPK-----------GTAHEMPK-- 55
+++VVVR RP +E + VV V + +V V NP+ G H+ PK
Sbjct: 7 TLQVVVRVRPPTPRELDSQRRPVVQVVDE--RVLVFNPEEPDGGFPGLKWGGTHDGPKKK 64
Query: 56 ----TFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRG 111
TF FD V+ A Q +++ T ++DS LQG+N ++FAYG TG GKT+TM G G
Sbjct: 65 GKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGREG 124
Query: 112 DPEKRGVIPNSFDHIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERP 170
DP G++ + ++ + +R Q + + V SY E+Y E+I DLL + L ++E P
Sbjct: 125 DP---GIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLL--EPKGPLAIREDP 179
Query: 171 DTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGL 230
D GV V+ LS S +++ ++ GN+NR+ T+ N SSRSHAIF I ++ +
Sbjct: 180 DKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVP 239
Query: 231 DGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD--GKST 288
++V K++L+DLAGSER + T A+GERL+E IN SL AL NV++AL D G+ T
Sbjct: 240 GLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKT 299
Query: 289 HIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNE 348
H+PYRDSKLTRLL+DSLGGN +TVM+A + P+S E+T TL+YA+RAK I+ + N
Sbjct: 300 HVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLSLKSNV 359
Query: 349 DPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGG 388
D + ++ +L+A+ + +++ + EGGG
Sbjct: 360 TSLDCHISQYATICQQLQAE-----VAALRKKLQVYEGGG 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,787,750
Number of Sequences: 37866
Number of extensions: 1310628
Number of successful extensions: 29641
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 698
Number of HSP's successfully gapped in prelim test: 1220
Number of HSP's that attempted gapping in prelim test: 12094
Number of HSP's gapped (non-prelim): 8753
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.