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Search of human proteins with 4758148
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758148 DNA fragmentation factor, 45kDa, alpha polypeptide
isoform 1 [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758148 DNA fragmentation factor, 45kDa, alpha polypeptide is... 644 0.0
gi|47132600 DNA fragmentation factor, 45kDa, alpha polypeptide i... 508 e-144
gi|38158011 cell death-inducing DFFA-like effector a isoform 2 [... 58 1e-08
gi|4557465 cell death-inducing DFFA-like effector a isoform 1 [H... 58 1e-08
gi|23943904 cell death-inducing DFFA-like effector c [Homo sapiens] 50 2e-06
gi|93102358 cell death-inducing DFFA-like effector b [Homo sapiens] 46 5e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 43 4e-04
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 41 0.001
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 39 0.008
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 39 0.008
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 39 0.008
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 39 0.008
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 37 0.019
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 37 0.019
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 37 0.024
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 37 0.032
gi|22749429 coiled-coil domain containing 89 [Homo sapiens] 37 0.032
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 36 0.042
gi|7705415 hook homolog 1 [Homo sapiens] 36 0.042
gi|16262452 cingulin [Homo sapiens] 36 0.054
gi|229577185 epidermal growth factor receptor pathway substrate ... 35 0.071
gi|4503593 epidermal growth factor receptor pathway substrate 15... 35 0.071
gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo sa... 35 0.071
gi|45505178 cancer antigen 1 [Homo sapiens] 35 0.093
gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] 35 0.093
gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens] 35 0.093
gi|10864047 epidermal growth factor receptor pathway substrate 1... 35 0.093
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 35 0.093
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 35 0.12
gi|55770834 centromere protein F [Homo sapiens] 34 0.16
>gi|4758148 DNA fragmentation factor, 45kDa, alpha polypeptide
isoform 1 [Homo sapiens]
Length = 331
Score = 644 bits (1660), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT 60
MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT
Sbjct: 1 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT 60
Query: 61 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA 120
LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA
Sbjct: 61 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA 120
Query: 121 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD 180
GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD
Sbjct: 121 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD 180
Query: 181 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH 240
QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH
Sbjct: 181 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH 240
Query: 241 ILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQT 300
ILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQT
Sbjct: 241 ILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQT 300
Query: 301 QSLHSLRSISASKASPPGDLQNPKRARQDPT 331
QSLHSLRSISASKASPPGDLQNPKRARQDPT
Sbjct: 301 QSLHSLRSISASKASPPGDLQNPKRARQDPT 331
>gi|47132600 DNA fragmentation factor, 45kDa, alpha polypeptide
isoform 2 [Homo sapiens]
Length = 268
Score = 508 bits (1309), Expect = e-144
Identities = 261/262 (99%), Positives = 262/262 (100%)
Query: 1 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT 60
MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT
Sbjct: 1 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT 60
Query: 61 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA 120
LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA
Sbjct: 61 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA 120
Query: 121 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD 180
GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD
Sbjct: 121 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD 180
Query: 181 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH 240
QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH
Sbjct: 181 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH 240
Query: 241 ILTALREKQAPELSLSSQDLEL 262
ILTALREKQAPELSLSSQDLE+
Sbjct: 241 ILTALREKQAPELSLSSQDLEV 262
>gi|38158011 cell death-inducing DFFA-like effector a isoform 2
[Homo sapiens]
Length = 253
Score = 58.2 bits (139), Expect = 1e-08
Identities = 33/70 (47%), Positives = 43/70 (61%), Gaps = 3/70 (4%)
Query: 26 NYSRE-QHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTK 84
N+ R + GV AS L++L SK D L I L VTLVL EDGT+VD +++F L NT
Sbjct: 75 NHDRSSRRGVMASSLQELISKTLDALVIATGL--VTLVLEEDGTVVDTEEFFQTLGDNTH 132
Query: 85 FVALASNEKW 94
F+ L +KW
Sbjct: 133 FMILEKGQKW 142
>gi|4557465 cell death-inducing DFFA-like effector a isoform 1 [Homo
sapiens]
Length = 219
Score = 58.2 bits (139), Expect = 1e-08
Identities = 33/70 (47%), Positives = 43/70 (61%), Gaps = 3/70 (4%)
Query: 26 NYSRE-QHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTK 84
N+ R + GV AS L++L SK D L I L VTLVL EDGT+VD +++F L NT
Sbjct: 41 NHDRSSRRGVMASSLQELISKTLDALVIATGL--VTLVLEEDGTVVDTEEFFQTLGDNTH 98
Query: 85 FVALASNEKW 94
F+ L +KW
Sbjct: 99 FMILEKGQKW 108
>gi|23943904 cell death-inducing DFFA-like effector c [Homo sapiens]
Length = 238
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 19 KPCLLRRNYSREQHGVAASCLEDLRSKACDILAI-DKSLTPVTLVLAEDGTIVDDDDYFL 77
+PC + + G+ A LEDL K D L + DK P LVL EDGT V+ ++YF
Sbjct: 43 RPCRVSTADRSVRKGIMAYSLEDLLLKVRDTLMLADK---PFFLVLEEDGTTVETEEYFQ 99
Query: 78 CLPSNTKFVALASNEKWAYNNSDG 101
L +T F+ L +KW + G
Sbjct: 100 ALAGDTVFMVLQKGQKWQPPSEQG 123
>gi|93102358 cell death-inducing DFFA-like effector b [Homo sapiens]
Length = 219
Score = 45.8 bits (107), Expect = 5e-05
Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 3/67 (4%)
Query: 33 GVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNE 92
G+ A+ ++L +KA + L ++ LT LVL EDGT VD +D+F L +T + L S +
Sbjct: 50 GLTAATRQELLAKALETLLLNGVLT---LVLEEDGTAVDSEDFFQLLEDDTCLMVLQSGQ 106
Query: 93 KWAYNNS 99
W+ S
Sbjct: 107 SWSPTRS 113
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 42.7 bits (99), Expect = 4e-04
Identities = 38/180 (21%), Positives = 83/180 (46%), Gaps = 13/180 (7%)
Query: 125 KNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREE 184
KN+ QL++D +I ++ + ++ ++AQ L+ ++Q+ Q EE
Sbjct: 352 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQ-----------LRSRIKQMTTQGEE 400
Query: 185 VRQSKQLLQ-LYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILT 243
+R+ K+ + + LEK S K EE++ E+D I + + + L+
Sbjct: 401 LREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELS 460
Query: 244 ALREKQAPELSLSSQD-LELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQS 302
++++ + SS++ + + K K LA KK +T + + ++ + L+++QS
Sbjct: 461 RVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQS 520
Score = 38.1 bits (87), Expect = 0.011
Identities = 27/108 (25%), Positives = 50/108 (46%)
Query: 155 SDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKA 214
S+L +LRQ L + QQ Q EE + ++ +++L E L K+ ++
Sbjct: 1272 SELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQ 1331
Query: 215 AFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLEL 262
E ++ T + +E S ++ + + L+EK+ SLS Q +L
Sbjct: 1332 QAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDL 1379
Score = 33.1 bits (74), Expect = 0.35
Identities = 59/266 (22%), Positives = 109/266 (40%), Gaps = 17/266 (6%)
Query: 36 ASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWA 95
A ++L + A ++ +K L +A+ + D L +N K + E
Sbjct: 979 AKLKKELENTALELSQKEKQFNAKMLEMAQANS-AGISDAVSRLETNQKEQIESLTEVHR 1037
Query: 96 YNNSDGGTAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCS 155
+D + W + + +E ++ + +++ E I+L E +M + +
Sbjct: 1038 RELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEM--NKEIT 1095
Query: 156 DLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALE-------KEGSLLSK 208
L +E + T+ LQ L+Q + Q + L+ +L+ LE KE + L +
Sbjct: 1096 WLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQE 1155
Query: 209 Q-EESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKED 267
Q E K E+ V S+ ++D S L + EK L S + + +++E
Sbjct: 1156 QLVELKMLAEEDKRKVSELTSKLKTTDEEFQS--LKSSHEKSNKSLEDKSLEFKKLSEE- 1212
Query: 268 PKALAVALNWDIKKTETVQEACEREL 293
LA+ L+ KKTE + EA EL
Sbjct: 1213 ---LAIQLDICCKKTEALLEAKTNEL 1235
Score = 31.2 bits (69), Expect = 1.3
Identities = 29/146 (19%), Positives = 65/146 (44%), Gaps = 26/146 (17%)
Query: 106 ISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLV--------------- 150
I QE D++ LK + +QL + ++ + E++L+M +
Sbjct: 1979 IKQEQEDLE-------LKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELL 2031
Query: 151 ---DAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSK-QLLQLYLQALEKEGSLL 206
+ L +++ + ++R +++LD REE +K + LQ L+ L+K+
Sbjct: 2032 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQK 2091
Query: 207 SKQEESKAAFGEEVDAVDTGISRETS 232
+QEE+ + + T ++++T+
Sbjct: 2092 LEQEENPGNDNVTIMELQTQLAQKTT 2117
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/194 (22%), Positives = 94/194 (48%), Gaps = 28/194 (14%)
Query: 129 RQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQS------CATVQRLQHTLQQVLDQR 182
+Q+K+ L + DLQ+ VD + + Q R C + H LD+
Sbjct: 1223 QQVKQKLEK----DKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKV 1278
Query: 183 EEVRQ--SKQLLQL------YLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSD 234
++ + Q +L +L+ LE++ +L+++ K+ F +++ + + +ET S
Sbjct: 1279 TQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQ 1338
Query: 235 VALASHILTA------LREKQAPELSLSSQDLELVTKEDPKALAVALNWD---IKKTETV 285
ALA + A LRE+ E + ++ ++K + + + + ++ I++TE +
Sbjct: 1339 SALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDL 1398
Query: 286 QEACERELALRLQQ 299
++A ++ELA+RLQ+
Sbjct: 1399 EDA-KKELAIRLQE 1411
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 38.5 bits (88), Expect = 0.008
Identities = 49/207 (23%), Positives = 91/207 (43%), Gaps = 27/207 (13%)
Query: 129 RQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQS 188
+Q E S L +DL +++ A L + C T L+ L + + EE+++S
Sbjct: 1215 KQKLEKEKSEFKLEIDDLSSSMESVSKSKAN-LEKICRT---LEDQLSEARGKNEEIQRS 1270
Query: 189 KQLLQLYLQALEKEGSLLSKQEE-----------SKAAFGEEVDAVDTGISRETSSDVAL 237
L L+ E LS+Q E SK AF ++ + + + E + AL
Sbjct: 1271 LSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 1330
Query: 238 A------SHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWD---IKKTETVQEA 288
A H LRE+ E ++ ++K + + ++ I++TE ++EA
Sbjct: 1331 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1390
Query: 289 CERELALRLQQTQSLHSLRSISASKAS 315
+++LA RLQ ++ + +++A AS
Sbjct: 1391 -KKKLAQRLQDSE--EQVEAVNAKCAS 1414
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 38.5 bits (88), Expect = 0.008
Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 14/186 (7%)
Query: 145 DLQMLVDAPCSD---LAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEK 201
DLQ + A D + +L + A ++ + +QQ+ +Q E + ++ +Q LQ E+
Sbjct: 794 DLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAH--VQELLQCSER 851
Query: 202 EGSLLSKQEESKAAFGEEVDAVDTGISR-ETSSDVALASH--ILTALREKQAPELSLSSQ 258
EG+L ++ + EE+ A+ +S+ + SS+ A H + L L Q
Sbjct: 852 EGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQ 911
Query: 259 DLELVTK----EDPKALAVALNWDIKKTET-VQEACERELALRLQQTQSL-HSLRSISAS 312
L + E+ A AV D K+ + +E ER++A Q+ +SL L++ A+
Sbjct: 912 VCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAA 971
Query: 313 KASPPG 318
S PG
Sbjct: 972 AGSLPG 977
Score = 33.1 bits (74), Expect = 0.35
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 25/178 (14%)
Query: 170 RLQHTLQQVLDQREEVRQS--------------KQLLQLYLQALEKEGSLLSKQEESKAA 215
+L T Q Q EE+RQ+ QLL+ LQAL+ + L ++E +
Sbjct: 599 QLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQG 658
Query: 216 FGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVAL 275
++A I + + +L + K+A + ++ ++ L +KE L
Sbjct: 659 SLASLEAEQASIRHLGDQ---MEASLLAVRKAKEAMKAQMAEKEAILQSKEGE---CQQL 712
Query: 276 NWDIKKTETVQEACEREL-ALRLQQTQSLHSLRSISASK----ASPPGDLQNPKRARQ 328
++++ + + EA REL AL Q Q + ++A K PP D + + A Q
Sbjct: 713 REEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQ 770
Score = 30.0 bits (66), Expect = 3.0
Identities = 45/194 (23%), Positives = 89/194 (45%), Gaps = 23/194 (11%)
Query: 129 RQLKEDLSSIILLSEE------DLQMLVDAPCSDLAQELRQSCA-TVQR------LQHTL 175
R L+E+LS SEE +LQ + +D A+ Q CA TV++ L +
Sbjct: 871 RALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAV 930
Query: 176 QQVLDQREEVRQSKQLLQLYLQALEKE-GSLLSKQEESKAAFGEEVDAVDTGISRETSSD 234
Q++ D +E + ++ L+ + L++E SL K + +KAA G + + +++
Sbjct: 931 QELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAG-SLPGLQAQLAQAEQRA 989
Query: 235 VALASHILTALREKQAPELSLSSQDLELVTK-----EDPKALAVALNWDIKKTETVQEAC 289
+L A +E + LS++ ++ ++ E+ K+L L ++ + +EA
Sbjct: 990 QSLQE---AAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEEAV 1046
Query: 290 ERELALRLQQTQSL 303
E+ A + + L
Sbjct: 1047 EKLKATQADMGEKL 1060
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 38.5 bits (88), Expect = 0.008
Identities = 58/231 (25%), Positives = 100/231 (43%), Gaps = 23/231 (9%)
Query: 107 SQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQE--LRQS 164
S++ D ++ + LK + QLKE +++ +LQ +D ++ L+QS
Sbjct: 445 SEKLMDKEQQVADLQLKLSRLEEQLKEKVTN-----STELQHQLDKTKQQHQEQQALQQS 499
Query: 165 C-ATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEE---SKAAFGEEV 220
A ++ Q+ L+QVL Q + Q Q L+ LQ ++ SLL K+ E +K GE
Sbjct: 500 TTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGE 559
Query: 221 DAVDTGISRETSSDVALASHILTALR-----EKQAPEL---SLSSQDLELVTKED-PKAL 271
AV + + + + + L+ KQA E + Q L +D +L
Sbjct: 560 TAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSL 619
Query: 272 AVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDLQN 322
++N + + E+ E+ L +Q L S A+K + DLQN
Sbjct: 620 ETSVN---ELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQN 667
Score = 32.3 bits (72), Expect = 0.60
Identities = 37/141 (26%), Positives = 63/141 (44%), Gaps = 15/141 (10%)
Query: 129 RQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQS 188
++L+ D + E+ LQ L Q+ RQ ++ L + L+ +E+ S
Sbjct: 733 KKLEADSLEVKASKEQALQDL---------QQQRQLNTDLELRATELSKQLEMEKEIVSS 783
Query: 189 KQL-LQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETS-SDVALASHILTALR 246
+L LQ +ALE L+KQEE K ++ + +S+ET L + I T +
Sbjct: 784 TRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET----LSQETKIQHEELNNRIQTTVT 839
Query: 247 EKQAPELSLSSQDLELVTKED 267
E Q ++ + EL T +D
Sbjct: 840 ELQKVKMEKEALMTELSTVKD 860
Score = 29.3 bits (64), Expect = 5.1
Identities = 45/226 (19%), Positives = 99/226 (43%), Gaps = 28/226 (12%)
Query: 122 LKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQ 181
++ +N ++ KE S+ E Q+ ++ + + ++L Q+ T+++ + QQ+
Sbjct: 903 VQMENTLKEQKELKKSLEKEKEASHQLKLEL--NSMQEQLIQAQNTLKQNEKEEQQLQGN 960
Query: 182 REEVRQSKQLLQLYLQALEKEGSL---------------LSKQEESKAAFGEEVDAVDTG 226
E++QS + + ++AL+ E + L++ + AA E++ +
Sbjct: 961 INELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNN 1020
Query: 227 I--SRET-----SSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDI 279
S+ET S S +L ++ ++ E LS +L++ + L I
Sbjct: 1021 YEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKL---I 1077
Query: 280 KKTETVQEACERELALRLQQTQS-LHSLRSISASKASPPGDLQNPK 324
++ +T + E++ A + QQ Q +L+ I K+ +L N K
Sbjct: 1078 QELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK 1123
Score = 28.5 bits (62), Expect = 8.7
Identities = 38/190 (20%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 140 LLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQS-------KQLL 192
L + L ++ ++L+++L V + LQ+ + E ++Q KQ+L
Sbjct: 753 LQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQIL 812
Query: 193 QLYLQALEKEGSL---------------LSKQEESKAAFGEEVDAVDTGISRETSSDVAL 237
+ + L +E + L K + K A E+ V +S+ + S
Sbjct: 813 KQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNS 872
Query: 238 ASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRL 297
S EK+ + + DLE KE L V + +K+ + ++++ E+E
Sbjct: 873 KSEF-----EKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASH 927
Query: 298 QQTQSLHSLR 307
Q L+S++
Sbjct: 928 QLKLELNSMQ 937
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 38.5 bits (88), Expect = 0.008
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 133 EDLSSIILLSEEDLQMLVDAPCSDLAQELRQS------CATVQRLQHTLQQVLDQREEVR 186
E+ ++ LLS+E Q L + QE+++ C +RL+ + + +Q E +R
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLR 382
Query: 187 QSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALR 246
+ +Q L+ + L KE L KQE+ E + + + ++ +H L
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKL---- 438
Query: 247 EKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSL 306
+KQ E S +DL + K A+ L +K E ++ E L QQ Q L +
Sbjct: 439 DKQLAEPQCSFEDL-----NNEKKSALQLEQQVK--ELQEKLDEEHLEAASQQNQQLETQ 491
Query: 307 RSISA 311
S+ A
Sbjct: 492 LSLVA 496
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 37.4 bits (85), Expect = 0.019
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 133 EDLSSIILLSEEDLQMLVDAP---CSDLAQELRQS---CATVQRLQHTLQQVLDQREEVR 186
E+ ++ LLS+E Q L + AQ +R+ C +RL+ + + +Q E +R
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382
Query: 187 QSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALR 246
+ +Q L+ + L KE L KQE+ E + + + ++ +H L
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKL---- 438
Query: 247 EKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSL 306
+KQ E S +DL + K A+ L +K E ++ E L Q+ Q L +
Sbjct: 439 DKQLAEPQCSFEDL-----NNEKKSALQLEQQVK--ELQEKLDEEHLEAASQRNQQLETQ 491
Query: 307 RSISA 311
S+ A
Sbjct: 492 LSLVA 496
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 37.4 bits (85), Expect = 0.019
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 133 EDLSSIILLSEEDLQMLVDAP---CSDLAQELRQS---CATVQRLQHTLQQVLDQREEVR 186
E+ ++ LLS+E Q L + AQ +R+ C +RL+ + + +Q E +R
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382
Query: 187 QSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALR 246
+ +Q L+ + L KE L KQE+ E + + + ++ +H L
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKL---- 438
Query: 247 EKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSL 306
+KQ E S +DL + K A+ L +K E ++ E L Q+ Q L +
Sbjct: 439 DKQLAEPQCSFEDL-----NNEKKSALQLEQQVK--ELQEKLDEEHLEAASQRNQQLETQ 491
Query: 307 RSISA 311
S+ A
Sbjct: 492 LSLVA 496
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 37.0 bits (84), Expect = 0.024
Identities = 46/185 (24%), Positives = 79/185 (42%), Gaps = 17/185 (9%)
Query: 133 EDLSSIILLSEEDLQMLVDAP---CSDLAQELRQS---CATVQRLQHTLQQVLDQREEVR 186
E+ ++ LLS+E Q L + AQ +R+ C +RL+ + + +Q E +R
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382
Query: 187 QSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALR 246
+ +Q L+ + L KE L KQE+ E + + + ++ +H L
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKL---- 438
Query: 247 EKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSL 306
+KQ E S +DL + K A+ L +K E ++ E L Q Q L +
Sbjct: 439 DKQLAEPQCSFEDL-----NNEKKSALQLEQQVK--ELQEKLDEEHLEAASHQNQQLETQ 491
Query: 307 RSISA 311
S+ A
Sbjct: 492 LSLVA 496
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 36.6 bits (83), Expect = 0.032
Identities = 53/256 (20%), Positives = 105/256 (41%), Gaps = 38/256 (14%)
Query: 106 ISQESFDVDETDSGAGLKWKNVARQLKEDLSSI-ILLSEED-----LQMLVDAPCSDLAQ 159
+SQ ++++ G + L +L+++ + ++D L+ + LAQ
Sbjct: 478 LSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQ 537
Query: 160 ELRQSCATVQRLQHTLQQV-------------LDQREEVRQSKQLLQLYLQALEKEGSL- 205
L+Q Q L+H ++Q+ + +++E + QL A E+E SL
Sbjct: 538 TLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLR 597
Query: 206 --------LSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSS 257
L E+ KAA +++ + + + + + + A REK ELS
Sbjct: 598 ERDAALKQLEALEKEKAA---KLEILQQQLQVANEARDSAQTSVTQAQREK--AELSRKV 652
Query: 258 QDL----ELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASK 313
++L E +E +A A +++ Q+A E+E + ++ Q L+++ S
Sbjct: 653 EELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQ-EKDQLQEQLQALKESL 711
Query: 314 ASPPGDLQNPKRARQD 329
G L+ KR D
Sbjct: 712 KVTKGSLEEEKRRAAD 727
Score = 29.6 bits (65), Expect = 3.9
Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 37/143 (25%)
Query: 125 KNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREE 184
K ++L+E L S+ L +E+ +ELR A +RL H LQQ + +E
Sbjct: 1625 KQQNQELQEQLRSLEQLQKEN-------------KELR---AEAERLGHELQQAGLKTKE 1668
Query: 185 VRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTA 244
Q+ + L +++LE + + +Q F DA+ +
Sbjct: 1669 AEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKS------------------- 1709
Query: 245 LREKQA-PELSLSSQDLELVTKE 266
RE QA P+L LS L+L +E
Sbjct: 1710 -REPQAKPQLDLSIDSLDLSCEE 1731
>gi|22749429 coiled-coil domain containing 89 [Homo sapiens]
Length = 374
Score = 36.6 bits (83), Expect = 0.032
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 29/204 (14%)
Query: 135 LSSIILLSEEDLQMLVDAPCSDLAQEL--------RQSCATVQRLQHTL----QQVLDQR 182
L S L EE + + C L EL + +C R + L QQ
Sbjct: 164 LFSQALKDEEAKVLQLTVRCEALTGELETLKERCAQDACQAQAREKELLELQSQQACTHT 223
Query: 183 EEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHIL 242
+E Q + LQ Q ++ ++K EE+ ++ +E+ A ++RE + L+
Sbjct: 224 KETEQLRSQLQTLKQQHQQAVEQIAKAEETHSSLSQELQARLQTVTREKEELLQLSIERG 283
Query: 243 TALREKQAPELSLSSQDLELVTKEDPKAL------AVALNWDI------KKTETVQEACE 290
L+ KQA E+ + LE+ ++ AL AVA++ ++ +K + +Q+A +
Sbjct: 284 KVLQNKQA-EICQLEEKLEIANEDRKHALERFEQEAVAVDSNLRVRELQRKVDGIQKAYD 342
Query: 291 RELALRLQ-QTQSLHSLRSISASK 313
LRLQ + HSL +S +
Sbjct: 343 E---LRLQSEAFKKHSLDLLSKER 363
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 36.2 bits (82), Expect = 0.042
Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 16/163 (9%)
Query: 169 QRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGIS 228
Q+L+ L ++ ++ ++ LLQ Q L+K S L + + K EV + S
Sbjct: 995 QQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNAS 1054
Query: 229 RETSSDV---ALASHILTALREKQAPELSLSSQDLEL----------VTKEDPKALAVAL 275
D+ L + T ++ + LS S +DL L + + AL A
Sbjct: 1055 PHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAK 1114
Query: 276 NWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPG 318
+ +++T +++ R+ AL+ Q H L S PPG
Sbjct: 1115 EFLVQQTRSMR---RRQTALKAAQQHWRHELASAQEVAKDPPG 1154
Score = 30.0 bits (66), Expect = 3.0
Identities = 52/231 (22%), Positives = 89/231 (38%), Gaps = 47/231 (20%)
Query: 108 QESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQS--- 164
+E + + A L+ KN RQ+ E L I SE+ Q ++A Q+LR+
Sbjct: 700 REELESQQKAERASLEQKN--RQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEG 757
Query: 165 -------------CATVQRLQHTLQ--------------QVLDQREEVRQSKQLLQLYLQ 197
A ++RL +L+ Q Q+EE + K L Q+ +
Sbjct: 758 ERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHR 817
Query: 198 ALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSS 257
+K + + E + E+ V+ R L ++E+ ++ +
Sbjct: 818 VHQKSYHVAGYEHELSSLLREKRQEVEGEHERR-----------LDKMKEEHQQVMAKAR 866
Query: 258 QDLELVTKEDPKALAVALNWDIKKTETVQEACEREL-ALRLQQTQSLHSLR 307
+ E E+ K A L + E +Q A EREL +R +Q + L LR
Sbjct: 867 EQYE---AEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLR 914
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 36.2 bits (82), Expect = 0.042
Identities = 26/97 (26%), Positives = 53/97 (54%), Gaps = 10/97 (10%)
Query: 131 LKEDLSSIILLSEEDLQM--LVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQS 188
L+E + +++ + ++L ++ +P +D EL Q ++R LQ+ L ++EE+RQ
Sbjct: 144 LEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQ---LKRALEELQEALAEKEELRQR 200
Query: 189 KQLLQLYLQALEKE-GSLLSKQEESKAAFGEEVDAVD 224
+ L + + L+ E SL+S+ E E++D +D
Sbjct: 201 CEELDMQVTTLQDEKNSLVSENE----MMNEKLDQLD 233
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 35.8 bits (81), Expect = 0.054
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 168 VQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKA----AFGEEVDAV 223
+QRL+ LQ +R+ R K+LL LQ LE+E + ++ +A E+V +
Sbjct: 915 IQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRL 974
Query: 224 DTGISRETSSDVALASHI------LTALREKQAPELSLSSQDLE 261
+T + E ++ L + + LR + E S + QDLE
Sbjct: 975 ETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERS-ARQDLE 1017
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 35.4 bits (80), Expect = 0.071
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 27/170 (15%)
Query: 126 NVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEV 185
NV + LKE +ED + DL E+++ +Q+LQ QQV + +E+
Sbjct: 37 NVEQDLKE---------KEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDEL 87
Query: 186 RQSKQLLQLYLQALEK----EGSLLS-------KQEESKAAFGEEVDAVDTGISR----- 229
+ K L+ L+ + K E L+S QE + + EE+ +SR
Sbjct: 88 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
Query: 230 -ETSSDVALASHILTALREK-QAPELSLSSQDLELVTKEDPKALAVALNW 277
E V L L++ Q + +SS ++L+ +D + LNW
Sbjct: 148 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 35.4 bits (80), Expect = 0.071
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 27/170 (15%)
Query: 126 NVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEV 185
NV + LKE +ED + DL E+++ +Q+LQ QQV + +E+
Sbjct: 351 NVEQDLKE---------KEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDEL 401
Query: 186 RQSKQLLQLYLQALEK----EGSLLS-------KQEESKAAFGEEVDAVDTGISR----- 229
+ K L+ L+ + K E L+S QE + + EE+ +SR
Sbjct: 402 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 461
Query: 230 -ETSSDVALASHILTALREK-QAPELSLSSQDLELVTKEDPKALAVALNW 277
E V L L++ Q + +SS ++L+ +D + LNW
Sbjct: 462 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 511
>gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo
sapiens]
Length = 596
Score = 35.4 bits (80), Expect = 0.071
Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 21/177 (11%)
Query: 160 ELRQSCATVQRLQHTLQ-QVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGE 218
+L+Q+ QR Q L QVL ++E RQ +Q L+ ++ + + L E K +FG
Sbjct: 316 KLKQASQKSQRAQQVLHLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTSFGP 375
Query: 219 EVDAVDTGIS-------------RETSSDV-ALASHIL---TALREKQA--PELSLSSQD 259
++ + +E+ ++V A AS IL L++ + L L +QD
Sbjct: 376 ALEETQWEVCQKSGEISLLKQQLKESQTEVNAKASEILGLKAQLKDTRGKLEGLELRTQD 435
Query: 260 LELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASP 316
LE + L V N ++++ + E ++ L Q+ Q L + +++ P
Sbjct: 436 LEGALRTKGLELEVCEN-ELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGPP 491
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 35.0 bits (79), Expect = 0.093
Identities = 44/206 (21%), Positives = 85/206 (41%), Gaps = 32/206 (15%)
Query: 126 NVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEV 185
+V +LKE++ +I ED ++ E + T+Q L+ L +E
Sbjct: 216 DVINKLKENVEELI----EDKYKII--------LEKNDTKKTLQNLEEVLANTQKHLQES 263
Query: 186 RQSKQLLQL---------------YLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRE 230
R K++LQL Y+ ++++ +S+ E ++ + V+ +
Sbjct: 264 RNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLK 323
Query: 231 TSSDVALASHILTALREKQAPE---LSLSS--QDLELVTKEDPKALAVALNWDIKKTETV 285
+ A AS + REK+A E LSL Q LE E+ + L L + + +
Sbjct: 324 KELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNL 383
Query: 286 QEACERELALRLQQTQSLHSLRSISA 311
Q E E ++ Q ++ +++ +A
Sbjct: 384 QFMSENERTKNIKLQQQINEVKNENA 409
>gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]
Length = 758
Score = 35.0 bits (79), Expect = 0.093
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Query: 158 AQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQE------E 211
+Q R + A + + Q +LQ+ L REE +Q ++L++ + EK L+K+E
Sbjct: 124 SQSPRAAAAALSQ-QQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKR 182
Query: 212 SKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKAL 271
K +GEE T + L + I EK+ L ++L KE K +
Sbjct: 183 EKMGWGEEYMGY-TNTDNPFGDNNLLGTFIWNKALEKKGIS-HLEEKEL----KERNKRI 236
Query: 272 AVALNWDIKKTETVQEACERELALRLQQTQSL 303
+++K + ++ ERE A+R Q+ + L
Sbjct: 237 QEDNRLELQKVKQLRLEREREKAMREQELEML 268
>gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens]
Length = 758
Score = 35.0 bits (79), Expect = 0.093
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Query: 158 AQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQE------E 211
+Q R + A + + Q +LQ+ L REE +Q ++L++ + EK L+K+E
Sbjct: 124 SQSPRAAAAALSQ-QQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKR 182
Query: 212 SKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKAL 271
K +GEE T + L + I EK+ L ++L KE K +
Sbjct: 183 EKMGWGEEYMGY-TNTDNPFGDNNLLGTFIWNKALEKKGIS-HLEEKEL----KERNKRI 236
Query: 272 AVALNWDIKKTETVQEACERELALRLQQTQSL 303
+++K + ++ ERE A+R Q+ + L
Sbjct: 237 QEDNRLELQKVKQLRLEREREKAMREQELEML 268
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 35.0 bits (79), Expect = 0.093
Identities = 42/173 (24%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Query: 160 ELRQSCATVQRLQHTLQQVLDQREE-VRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGE 218
++ Q A +QR +++L+Q + ++EE +RQ +Q L++E S L + E K +
Sbjct: 388 DISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQD 447
Query: 219 EVDAVDTGIS--RETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALN 276
+D +D + R+ SDV T + + + + SQ+ +L ++ED A +
Sbjct: 448 RLDEMDQQKAKLRDMLSDVRQKCQDETQM--ISSLKTQIQSQESDLKSQEDDLNRAKSEL 505
Query: 277 WDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDLQNPKRARQD 329
+++ ET E + A R+Q + SL+S L +RQ+
Sbjct: 506 NRLQQEETQLE--QSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQE 556
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 35.0 bits (79), Expect = 0.093
Identities = 38/181 (20%), Positives = 79/181 (43%), Gaps = 16/181 (8%)
Query: 141 LSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALE 200
L E++LQ ++ +QEL +S V L+ LQ+ R+++++ ++ + LE
Sbjct: 1060 LLEKELQEVIALT----SQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELE 1115
Query: 201 KEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDL 260
E L+ +S AA E ++T +++ + V L + L+ K+ + +
Sbjct: 1116 HEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQM----- 1170
Query: 261 ELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDL 320
K +AL +L K+ E V E+ A +++ + ++ S + +L
Sbjct: 1171 ----KHLVQALQASLE---KEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKEL 1223
Query: 321 Q 321
Q
Sbjct: 1224 Q 1224
Score = 29.6 bits (65), Expect = 3.9
Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 6/163 (3%)
Query: 150 VDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQ 209
+D+ +L QEL Q + + L ++ + +VRQ L+ +LQ+ +KE +
Sbjct: 876 LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETH 935
Query: 210 EESKAAFGEEVDAV---DTGISRETSSDVALASHILTALREKQAPELS-LSSQDLELVTK 265
+S E++ AV + + ++ A +T ++K S L+S E+ TK
Sbjct: 936 LQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTK 995
Query: 266 EDPKALAVA-LNWDIKKTETVQEACERELA-LRLQQTQSLHSL 306
AV L+ +++ +EA + EL LR Q S SL
Sbjct: 996 HKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSL 1038
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 34.7 bits (78), Expect = 0.12
Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 5/116 (4%)
Query: 103 TAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILL--SEEDLQMLVDAPCSDLAQE 160
T +S E +D T +GA L+ RQ+++ + +++L S Q+ VDA L E
Sbjct: 1896 TVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL--E 1953
Query: 161 LRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAF 216
L+Q ++ Q ++ L+ RE + +++ L Q +G L + S A F
Sbjct: 1954 LQQEVERLRSAQAQTERTLEARERAHR-QRVRGLEEQVSTLKGQLQQELRRSSAPF 2008
Score = 33.5 bits (75), Expect = 0.27
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 6/96 (6%)
Query: 129 RQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQR----LQHTLQQVLDQREE 184
R L+E L + ++ +Q DA Q LR + + R L H+LQ Q EE
Sbjct: 564 RALEEQLQRLRDKTDGAMQAHEDAQRE--VQRLRSANELLSREKSNLAHSLQVAQQQAEE 621
Query: 185 VRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEV 220
+RQ ++ LQ + L ++ L +++E G V
Sbjct: 622 LRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV 657
Score = 28.9 bits (63), Expect = 6.6
Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 23/195 (11%)
Query: 157 LAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQ----EES 212
L + LRQ +T+Q++ D+R +++ LQ L LE E + + E+
Sbjct: 1815 LREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKD 1874
Query: 213 KAAFGEEVDAVDTGISRETSSDVALAS------HILTA----LREKQAPELSLSSQDLEL 262
+ A +D V+ R V L++ LT L E Q L +Q + L
Sbjct: 1875 RVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVL 1934
Query: 263 VTKEDPKALAV-------ALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKAS 315
P L V L ++++ + Q ER L R + +R + ++
Sbjct: 1935 EQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEAR--ERAHRQRVRGLEEQVST 1992
Query: 316 PPGDLQNPKRARQDP 330
G LQ R P
Sbjct: 1993 LKGQLQQELRRSSAP 2007
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 34.3 bits (77), Expect = 0.16
Identities = 46/209 (22%), Positives = 87/209 (41%), Gaps = 26/209 (12%)
Query: 123 KWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQR 182
K K ++ +E+LS + Q L D C + L Q + + + LQ LD+
Sbjct: 388 KIKEKEKEFQEELSR----QQRSFQTL-DQECIQMKARLTQELQQAKNMHNVLQAELDKL 442
Query: 183 EEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHIL 242
V KQ L+ L+ KQ+ +A + + R + ++ +++L
Sbjct: 443 TSV---KQQLENNLEEF--------KQKLCRAEQAFQASQIKENELRRSMEEMKKENNLL 491
Query: 243 TALREKQAPELSLSSQDLELVTKEDPKALAVALNW--DIKKTETVQEACERELALRLQQT 300
+ E++A E+ LE K + L + N+ ++K T QE R+L ++ Q
Sbjct: 492 KSHSEQKAREVC----HLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQ 547
Query: 301 QSLHSLRSISASKASPPGDLQNPKRARQD 329
++ +L + + A DL+ + QD
Sbjct: 548 ENSLTLEKLKLAVA----DLEKQRDCSQD 572
Score = 32.7 bits (73), Expect = 0.46
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 23/164 (14%)
Query: 173 HTLQQVLDQREEVRQSKQLLQLYLQALEKE--------GSLLSKQEESKAAFGEEVDAVD 224
H L Q+ Q +E+R L+L LQ EKE L + E++K E+ ++
Sbjct: 278 HLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLN 337
Query: 225 TGISR--ETSSDVALASHILTALRE---KQAPELSLSSQD-------LELVTKEDPKALA 272
T++ AS TAL + K +LS Q+ LE KE K
Sbjct: 338 KCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQ 397
Query: 273 VALNWDIKKTETVQEAC---ERELALRLQQTQSLHSLRSISASK 313
L+ + +T+ + C + L LQQ +++H++ K
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDK 441
Score = 31.2 bits (69), Expect = 1.3
Identities = 31/180 (17%), Positives = 83/180 (46%), Gaps = 2/180 (1%)
Query: 122 LKWKNVARQ-LKEDLSSIILLSEEDLQM-LVDAPCSDLAQELRQSCATVQRLQHTLQQVL 179
+K KN +++ + DL I E L + + +DL ++ S +++ +H ++Q+
Sbjct: 526 MKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLN 585
Query: 180 DQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALAS 239
D+ + + + L L+ +KE L +++ + + E + + T + E + + +
Sbjct: 586 DKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKIN 645
Query: 240 HILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQ 299
H+ T L+ +Q + + L + ++ + ++ +++V+ ++ + LQQ
Sbjct: 646 HLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQ 705
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,965,401
Number of Sequences: 37866
Number of extensions: 492277
Number of successful extensions: 2230
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 1978
Number of HSP's gapped (non-prelim): 439
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.