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Search of human proteins with 4758018
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758018 calponin 2 isoform a [Homo sapiens]
(309 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758018 calponin 2 isoform a [Homo sapiens] 639 0.0
gi|41327730 calponin 2 isoform b [Homo sapiens] 543 e-155
gi|4502923 calponin 3 [Homo sapiens] 396 e-110
gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 363 e-101
gi|4507357 transgelin 2 [Homo sapiens] 135 4e-32
gi|56549135 transgelin 3 [Homo sapiens] 134 8e-32
gi|56549139 transgelin 3 [Homo sapiens] 134 8e-32
gi|56549137 transgelin 3 [Homo sapiens] 134 8e-32
gi|48255907 transgelin [Homo sapiens] 125 4e-29
gi|48255905 transgelin [Homo sapiens] 125 4e-29
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 65 6e-11
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 65 6e-11
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 65 6e-11
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 58 9e-09
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 49 7e-06
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 48 1e-05
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 47 2e-05
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 47 2e-05
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ... 43 4e-04
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 43 4e-04
gi|30181233 leucine-rich repeats and calponin homology (CH) doma... 42 5e-04
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 42 7e-04
gi|33859670 leucine-rich repeats and calponin homology (CH) doma... 41 0.002
gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 40 0.002
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 37 0.029
gi|14249428 leucine-rich repeats and calponin homology (CH) doma... 35 0.084
gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens] 34 0.14
gi|219842340 growth arrest-specific 2 [Homo sapiens] 32 0.71
gi|29540559 growth arrest-specific 2 [Homo sapiens] 32 0.71
gi|4885253 growth arrest-specific 2 [Homo sapiens] 32 0.71
>gi|4758018 calponin 2 isoform a [Homo sapiens]
Length = 309
Score = 639 bits (1648), Expect = 0.0
Identities = 309/309 (100%), Positives = 309/309 (100%)
Query: 1 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL 60
MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
Sbjct: 1 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL 60
Query: 61 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV 120
CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
Sbjct: 61 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV 120
Query: 121 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG 180
QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG
Sbjct: 121 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG 180
Query: 181 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC 240
MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
Sbjct: 181 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC 240
Query: 241 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP 300
DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP
Sbjct: 241 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP 300
Query: 301 PYYQEEAGY 309
PYYQEEAGY
Sbjct: 301 PYYQEEAGY 309
>gi|41327730 calponin 2 isoform b [Homo sapiens]
Length = 270
Score = 543 bits (1399), Expect = e-155
Identities = 270/309 (87%), Positives = 270/309 (87%), Gaps = 39/309 (12%)
Query: 1 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL 60
MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
Sbjct: 1 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL 60
Query: 61 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV 120
CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
Sbjct: 61 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV 120
Query: 121 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG 180
QVSLLALAGK MGTNKCASQSG
Sbjct: 121 QVSLLALAGK---------------------------------------MGTNKCASQSG 141
Query: 181 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC 240
MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
Sbjct: 142 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC 201
Query: 241 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP 300
DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP
Sbjct: 202 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP 261
Query: 301 PYYQEEAGY 309
PYYQEEAGY
Sbjct: 262 PYYQEEAGY 270
>gi|4502923 calponin 3 [Homo sapiens]
Length = 329
Score = 396 bits (1018), Expect = e-110
Identities = 203/310 (65%), Positives = 232/310 (74%), Gaps = 7/310 (2%)
Query: 4 TQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTILCTL 63
T FNKGPSYGLSAEVKN++ SKYD Q E +LR WIE +TG+SIGP+FQ GLKDG ILC L
Sbjct: 2 THFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCEL 61
Query: 64 MNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVS 123
+NKLQPGSV K+N S NW QLEN+ NFIKA+ +YGM P D+FEANDLFE+GNMTQVQ +
Sbjct: 62 INKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTT 121
Query: 124 LLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSGMTA 183
L+ALAG AKTKG + +DIGVKY+EKQ R FD+ +KAGQ VIGLQMGTNKCASQ+GMTA
Sbjct: 122 LVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTA 181
Query: 184 YGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNS 243
YGTRRHLYDPK P D +TISLQMGTNK ASQ GM APGTRR IYD KL DNS
Sbjct: 182 YGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNS 241
Query: 244 SMSLQMGYTQGANQSG-QVFGLGRQIYDPKYC--PQGTVADGAPSGTG----DCPDPGEV 296
++SLQMG + A+Q G V+GLGRQ+YDPKYC P V GTG + D
Sbjct: 242 TISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQ 301
Query: 297 PEYPPYYQEE 306
EYP Y E
Sbjct: 302 AEYPDEYHGE 311
>gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]
Length = 297
Score = 363 bits (933), Expect = e-101
Identities = 181/275 (65%), Positives = 215/275 (78%), Gaps = 3/275 (1%)
Query: 1 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL 60
MSS FN+GP+YGLSAEVKN+L KYD Q+E ELR WIEG+TG IG +F GLKDG IL
Sbjct: 1 MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIIL 60
Query: 61 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV 120
C +NKLQPGSV KIN S QNWHQLEN+ NFIKA+ YG+ P D+FEANDLFE+ N TQV
Sbjct: 61 CEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQV 120
Query: 121 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG 180
Q +LLALA AKTKG + V++GVKY+EKQER F+ ++ G+ +IGLQMGTNK ASQ G
Sbjct: 121 QSTLLALASMAKTKG--NKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQG 178
Query: 181 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC 240
MTAYGTRRHLYDPK P+D +TISLQMGTNK ASQ GMTAPGT+R I++ LG + C
Sbjct: 179 MTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHC 238
Query: 241 DNSSMSLQMGYTQGANQSGQ-VFGLGRQIYDPKYC 274
D ++SLQMG +GA+Q G V+GL RQ+YDPKYC
Sbjct: 239 DTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYC 273
Score = 44.7 bits (104), Expect = 1e-04
Identities = 20/34 (58%), Positives = 24/34 (70%)
Query: 166 IGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILP 199
+ LQMG+NK ASQ GMT YG R +YDPK + P
Sbjct: 243 VSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTP 276
>gi|4507357 transgelin 2 [Homo sapiens]
Length = 199
Score = 135 bits (341), Expect = 4e-32
Identities = 83/196 (42%), Positives = 114/196 (58%), Gaps = 12/196 (6%)
Query: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG------PDFQKGLKDGTIL 60
N+GP+YGLS EV+ ++ +YD E L WI +G +FQ LKDGT+L
Sbjct: 3 NRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVL 62
Query: 61 CTLMNKLQP---GSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117
C L+N L P V KI S + Q+E +S F++A YG+N D+F+ DL+E NM
Sbjct: 63 CELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNM 122
Query: 118 TQVQVSLLALAGKAKTK--GLQSG-VDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNK 174
VQ +L+ L G A + GL SG + K S++ RNF D ++ G+ VIGLQMGTN+
Sbjct: 123 ACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNR 182
Query: 175 CASQSGMTAYGTRRHL 190
ASQ+GMT YG R +
Sbjct: 183 GASQAGMTGYGMPRQI 198
>gi|56549135 transgelin 3 [Homo sapiens]
Length = 199
Score = 134 bits (338), Expect = 8e-32
Identities = 82/196 (41%), Positives = 114/196 (58%), Gaps = 12/196 (6%)
Query: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWI-----EGLTGLSIG-PDFQKGLKDGTIL 60
N+GPSYGLS EV+ ++ KYD E +L WI E + G FQK L DGT+L
Sbjct: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
Query: 61 CTLMNKLQPGS---VPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117
C L+N L P +PKI+ S + Q+E +S F+KA +YG+ D+F+ DL+E +M
Sbjct: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
Query: 118 TQVQVSLLALAGKAKTK--GLQSGVDIGV-KYSEKQERNFDDATMKAGQCVIGLQMGTNK 174
VQ +L+AL A TK G G + +++ R F + ++ GQ VIGLQMG+NK
Sbjct: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182
Query: 175 CASQSGMTAYGTRRHL 190
ASQ+GMT YG R +
Sbjct: 183 GASQAGMTGYGMPRQI 198
>gi|56549139 transgelin 3 [Homo sapiens]
Length = 199
Score = 134 bits (338), Expect = 8e-32
Identities = 82/196 (41%), Positives = 114/196 (58%), Gaps = 12/196 (6%)
Query: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWI-----EGLTGLSIG-PDFQKGLKDGTIL 60
N+GPSYGLS EV+ ++ KYD E +L WI E + G FQK L DGT+L
Sbjct: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
Query: 61 CTLMNKLQPGS---VPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117
C L+N L P +PKI+ S + Q+E +S F+KA +YG+ D+F+ DL+E +M
Sbjct: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
Query: 118 TQVQVSLLALAGKAKTK--GLQSGVDIGV-KYSEKQERNFDDATMKAGQCVIGLQMGTNK 174
VQ +L+AL A TK G G + +++ R F + ++ GQ VIGLQMG+NK
Sbjct: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182
Query: 175 CASQSGMTAYGTRRHL 190
ASQ+GMT YG R +
Sbjct: 183 GASQAGMTGYGMPRQI 198
>gi|56549137 transgelin 3 [Homo sapiens]
Length = 199
Score = 134 bits (338), Expect = 8e-32
Identities = 82/196 (41%), Positives = 114/196 (58%), Gaps = 12/196 (6%)
Query: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWI-----EGLTGLSIG-PDFQKGLKDGTIL 60
N+GPSYGLS EV+ ++ KYD E +L WI E + G FQK L DGT+L
Sbjct: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
Query: 61 CTLMNKLQPGS---VPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNM 117
C L+N L P +PKI+ S + Q+E +S F+KA +YG+ D+F+ DL+E +M
Sbjct: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
Query: 118 TQVQVSLLALAGKAKTK--GLQSGVDIGV-KYSEKQERNFDDATMKAGQCVIGLQMGTNK 174
VQ +L+AL A TK G G + +++ R F + ++ GQ VIGLQMG+NK
Sbjct: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNK 182
Query: 175 CASQSGMTAYGTRRHL 190
ASQ+GMT YG R +
Sbjct: 183 GASQAGMTGYGMPRQI 198
>gi|48255907 transgelin [Homo sapiens]
Length = 201
Score = 125 bits (315), Expect = 4e-29
Identities = 80/197 (40%), Positives = 117/197 (59%), Gaps = 13/197 (6%)
Query: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG-PD-----FQKGLKDGTIL 60
NKGPSYG+S EV++++ KYD + E L WI G +G PD FQ LK+G IL
Sbjct: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
Query: 61 CTLMNKLQP-GSVP-KI--NRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGN 116
L+N L P GS P K+ N + Q+E ++ F+KA YG+ D+F+ DLFE +
Sbjct: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
Query: 117 MTQVQVSLLALAGKAKTKG---LQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTN 173
M VQ +L+AL A TK + + +K +++ +R F ++ ++ G+ VIGLQMG+N
Sbjct: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSN 182
Query: 174 KCASQSGMTAYGTRRHL 190
+ ASQ+GMT YG R +
Sbjct: 183 RGASQAGMTGYGRPRQI 199
>gi|48255905 transgelin [Homo sapiens]
Length = 201
Score = 125 bits (315), Expect = 4e-29
Identities = 80/197 (40%), Positives = 117/197 (59%), Gaps = 13/197 (6%)
Query: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG-PD-----FQKGLKDGTIL 60
NKGPSYG+S EV++++ KYD + E L WI G +G PD FQ LK+G IL
Sbjct: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
Query: 61 CTLMNKLQP-GSVP-KI--NRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGN 116
L+N L P GS P K+ N + Q+E ++ F+KA YG+ D+F+ DLFE +
Sbjct: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
Query: 117 MTQVQVSLLALAGKAKTKG---LQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTN 173
M VQ +L+AL A TK + + +K +++ +R F ++ ++ G+ VIGLQMG+N
Sbjct: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSN 182
Query: 174 KCASQSGMTAYGTRRHL 190
+ ASQ+GMT YG R +
Sbjct: 183 RGASQAGMTGYGRPRQI 199
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 65.5 bits (158), Expect = 6e-11
Identities = 34/91 (37%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Query: 32 AELRTWIEGLTGLSIGP-DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSN 90
+E + WIE +TG S G DF+ GL++G +LC L+N ++PG V KINR L+N+
Sbjct: 25 SEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIIL 84
Query: 91 FIKAMVSYGMNPVDLFEANDLFESGNMTQVQ 121
F++ G+ LF+ +DL ++ N V+
Sbjct: 85 FLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 65.5 bits (158), Expect = 6e-11
Identities = 34/91 (37%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Query: 32 AELRTWIEGLTGLSIGP-DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSN 90
+E + WIE +TG S G DF+ GL++G +LC L+N ++PG V KINR L+N+
Sbjct: 25 SEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIIL 84
Query: 91 FIKAMVSYGMNPVDLFEANDLFESGNMTQVQ 121
F++ G+ LF+ +DL ++ N V+
Sbjct: 85 FLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 65.5 bits (158), Expect = 6e-11
Identities = 34/91 (37%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Query: 32 AELRTWIEGLTGLSIGP-DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSN 90
+E + WIE +TG S G DF+ GL++G +LC L+N ++PG V KINR L+N+
Sbjct: 25 SEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIIL 84
Query: 91 FIKAMVSYGMNPVDLFEANDLFESGNMTQVQ 121
F++ G+ LF+ +DL ++ N V+
Sbjct: 85 FLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 58.2 bits (139), Expect = 9e-09
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 12/112 (10%)
Query: 49 DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEA 108
DF+ L++G +LC L+NKL+PG + KINR L+N++ F+KA G+ LF
Sbjct: 86 DFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHP 145
Query: 109 NDLFESGNMTQVQ------------VSLLALAGKAKTKGLQSGVDIGVKYSE 148
DL + N V+ ++L L KA++ +G + +K E
Sbjct: 146 GDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNLKAFE 197
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 48.5 bits (114), Expect = 7e-06
Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 4/106 (3%)
Query: 51 QKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMN-PVDLFEAN 109
Q LKDG +LC L+ +L PG++ K+ ++ + E LSN + + G + ++ F+AN
Sbjct: 32 QASLKDGVVLCRLLERLLPGTIEKVYPEPRS--ESECLSNIREFLRGCGASLRLETFDAN 89
Query: 110 DLFESGNMTQVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFD 155
DL++ N +V SL+ L GL S + + S + ++FD
Sbjct: 90 DLYQGQNFNKVLSSLVTLNKVTADIGLGSD-SVCARPSSHRIKSFD 134
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 47.8 bits (112), Expect = 1e-05
Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 4/78 (5%)
Query: 51 QKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQ-LENLSNFIKAMVSYGMNPVDLFEAN 109
+ LK+G +LC L+N+L PGSV K Q + N+++F+K + V++F+ +
Sbjct: 32 KSSLKNGVVLCKLINRLMPGSVEKFCLDPQTEADCINNINDFLKGCATL---QVEIFDPD 88
Query: 110 DLFESGNMTQVQVSLLAL 127
DL+ N ++V +LLA+
Sbjct: 89 DLYSGVNFSKVLSTLLAV 106
>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 878
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 7/96 (7%)
Query: 49 DFQKGLKDGTILCTLMNKLQPGSVP----KINRSMQNWHQLENLSNFIKAM-VSYGMNPV 103
D + L+DG +LC L++ L PGS+ M + L+N+ F+K +G+
Sbjct: 32 DLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNS 91
Query: 104 DLFEANDLFESGNMTQV--QVSLLALAGKAKTKGLQ 137
+LF+ DLF+ + +V VS L+L A+ KG++
Sbjct: 92 ELFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIR 127
>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 839
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 7/96 (7%)
Query: 49 DFQKGLKDGTILCTLMNKLQPGSVP----KINRSMQNWHQLENLSNFIKAM-VSYGMNPV 103
D + L+DG +LC L++ L PGS+ M + L+N+ F+K +G+
Sbjct: 32 DLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNS 91
Query: 104 DLFEANDLFESGNMTQV--QVSLLALAGKAKTKGLQ 137
+LF+ DLF+ + +V VS L+L A+ KG++
Sbjct: 92 ELFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIR 127
>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 847
Score = 42.7 bits (99), Expect = 4e-04
Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Query: 49 DFQKGLKDGTILCTLMNKLQPGSVP----KINRSMQNWHQLENLSNFIKAMV-SYGMNPV 103
D + L+DG +LC L+N L+ S+ + M + L+N+ F+ A ++GM
Sbjct: 32 DLAQTLRDGVLLCQLLNNLRAHSINLKEINLRPQMSQFLCLKNIRTFLTACCETFGMRKS 91
Query: 104 DLFEANDLFESGNMTQVQVSLLALA 128
+LFEA DLF+ + +V +L L+
Sbjct: 92 ELFEAFDLFDVRDFGKVIETLSRLS 116
>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
sapiens]
Length = 803
Score = 42.7 bits (99), Expect = 4e-04
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 21/125 (16%)
Query: 51 QKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQ-LENLSNFIKA--------------- 94
Q LKDG +LC L+ +L PG++ K+ ++ + L N+ F++
Sbjct: 32 QASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLELLFPPSQ 91
Query: 95 ----MVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQ 150
+V+ + F+ANDL++ N +V SL+ L GL S + + S +
Sbjct: 92 PPQHLVTTILLSASTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSD-SVCARPSSHR 150
Query: 151 ERNFD 155
++FD
Sbjct: 151 IKSFD 155
>gi|30181233 leucine-rich repeats and calponin homology (CH) domain
containing 4 [Homo sapiens]
Length = 683
Score = 42.4 bits (98), Expect = 5e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 9/120 (7%)
Query: 2 SSTQFNKGPSYGLSAEVKNRLLSKYDPQKE--AELRTWIEGLTGLSIGPDFQKGLKDGTI 59
SS+Q GPS S ++ R + +K+ +LR +E + D + L G I
Sbjct: 511 SSSQSGSGPSSPDSV-LRPRRYPQVPDEKDLMTQLRQVLESRLQRPLPEDLAEALASGVI 569
Query: 60 LCTLMNKLQPGSVPKIN------RSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFE 113
LC L N+L+P SVP I+ + +N+ +F++A G+ DL +DL +
Sbjct: 570 LCQLANQLRPRSVPFIHVPSPAVPKLSALKARKNVESFLEACRKMGVPEADLCSPSDLLQ 629
>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
Length = 845
Score = 42.0 bits (97), Expect = 7e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 49 DFQKGLKDGTILCTLMNKLQPGSV----PKINRSMQNWHQLENLSNFIKAMV-SYGMNPV 103
+ + L+DG +LC L+N L P ++ + M + L+N+ F+ +G+
Sbjct: 32 ELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRS 91
Query: 104 DLFEANDLFESGNMTQVQVSLLALA 128
+LFEA DLF+ + +V +L AL+
Sbjct: 92 ELFEAFDLFDVQDFGKVIYTLSALS 116
>gi|33859670 leucine-rich repeats and calponin homology (CH) domain
containing 1 [Homo sapiens]
Length = 728
Score = 40.8 bits (94), Expect = 0.002
Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 10/121 (8%)
Query: 33 ELRTWIEGLTGLSIGPDFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQL------E 86
+LR IE +S+ D L DG +LC L+N ++P SV I+ +L
Sbjct: 585 QLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRR 644
Query: 87 NLSNFIKAMVSYGMNPVDLFEANDLFESG--NMTQVQVSLLALAGKA--KTKGLQSGVDI 142
N+ NF++A G+ DL D+ + ++ + +LLAL KA T L+S I
Sbjct: 645 NVENFLEACRKLGVPEADLCSPCDILQLDFRHIRKTVDTLLALGEKAPPPTSALRSRDLI 704
Query: 143 G 143
G
Sbjct: 705 G 705
>gi|154091020 leucine-rich repeats and calponin homology (CH) domain
containing 2 [Homo sapiens]
Length = 765
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 33 ELRTWIEGLTGLSIGPDFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQL------E 86
+LR +E + + D L DG +LC L N ++P SV I+ +L
Sbjct: 651 QLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPSPAVPKLSMAKCRR 710
Query: 87 NLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQSGV 140
N+ NF+ A G++ L + + E + +V V++ AL TK Q V
Sbjct: 711 NVENFLDACKKLGVSQERLCLPHHILEERGLVKVGVTVQALLELPTTKASQLSV 764
>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
sapiens]
Length = 753
Score = 36.6 bits (83), Expect = 0.029
Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 31/105 (29%)
Query: 51 QKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEAND 110
Q LKDG +LC L+ +L PG++ K F+AND
Sbjct: 32 QASLKDGVVLCRLLERLLPGTIEK------------------------------TFDAND 61
Query: 111 LFESGNMTQVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFD 155
L++ N +V SL+ L GL S + + S + ++FD
Sbjct: 62 LYQGQNFNKVLSSLVTLNKVTADIGLGSD-SVCARPSSHRIKSFD 105
>gi|14249428 leucine-rich repeats and calponin homology (CH) domain
containing 3 [Homo sapiens]
Length = 712
Score = 35.0 bits (79), Expect = 0.084
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 10 PSYGLSAEVKNRLLSKYDPQKEAEL------RTWIEGLTGLSIGPDFQKGLKDGTILCTL 63
PS + + + + + Q+E EL R IE +S+ D L DG +LC L
Sbjct: 632 PSAAPTTDSTDSITGQNSRQREEELELIDQLRKHIEYRLKVSLPCDLGAALTDGVVLCHL 691
Query: 64 MNKLQPGSVPKIN 76
N ++P SVP I+
Sbjct: 692 ANHVRPRSVPSIH 704
>gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens]
Length = 694
Score = 34.3 bits (77), Expect = 0.14
Identities = 29/127 (22%), Positives = 56/127 (44%), Gaps = 17/127 (13%)
Query: 31 EAELRTWIEGLTGLSIGPD-FQKGLKDGTILCTLMNKLQ----------PGSVP------ 73
+ +L W+ GL G+ + + + L +G +LC L++ LQ G+ P
Sbjct: 51 QEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPC 110
Query: 74 KINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKT 133
K + + ++ +N +NF+ G++ LFE+ L + QV + LL +
Sbjct: 111 KKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSR 170
Query: 134 KGLQSGV 140
G++ V
Sbjct: 171 YGVEPPV 177
>gi|219842340 growth arrest-specific 2 [Homo sapiens]
Length = 313
Score = 32.0 bits (71), Expect = 0.71
Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 24/158 (15%)
Query: 3 STQFNKGPSYGLSAEVKNRLLSKYD----PQKEAELRTWIEGLTGLSIGPD-FQKGLKDG 57
S + GP + L S+++ P KE +L W+ L G I + F + L +G
Sbjct: 6 SPKVRSGPGLSDMHQYSQWLASRHEANLLPMKE-DLALWLTNLLGKEITAETFMEKLDNG 64
Query: 58 TILCTLMNKLQPG-----------------SVP-KINRSMQNWHQLENLSNFIKAMVSYG 99
+LC L +Q +P K + ++ +N +NF+ G
Sbjct: 65 ALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLG 124
Query: 100 MNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQ 137
++ LFE+ L +V + LL L A G++
Sbjct: 125 VDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVE 162
>gi|29540559 growth arrest-specific 2 [Homo sapiens]
Length = 313
Score = 32.0 bits (71), Expect = 0.71
Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 24/158 (15%)
Query: 3 STQFNKGPSYGLSAEVKNRLLSKYD----PQKEAELRTWIEGLTGLSIGPD-FQKGLKDG 57
S + GP + L S+++ P KE +L W+ L G I + F + L +G
Sbjct: 6 SPKVRSGPGLSDMHQYSQWLASRHEANLLPMKE-DLALWLTNLLGKEITAETFMEKLDNG 64
Query: 58 TILCTLMNKLQPG-----------------SVP-KINRSMQNWHQLENLSNFIKAMVSYG 99
+LC L +Q +P K + ++ +N +NF+ G
Sbjct: 65 ALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLG 124
Query: 100 MNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQ 137
++ LFE+ L +V + LL L A G++
Sbjct: 125 VDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVE 162
>gi|4885253 growth arrest-specific 2 [Homo sapiens]
Length = 313
Score = 32.0 bits (71), Expect = 0.71
Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 24/158 (15%)
Query: 3 STQFNKGPSYGLSAEVKNRLLSKYD----PQKEAELRTWIEGLTGLSIGPD-FQKGLKDG 57
S + GP + L S+++ P KE +L W+ L G I + F + L +G
Sbjct: 6 SPKVRSGPGLSDMHQYSQWLASRHEANLLPMKE-DLALWLTNLLGKEITAETFMEKLDNG 64
Query: 58 TILCTLMNKLQPG-----------------SVP-KINRSMQNWHQLENLSNFIKAMVSYG 99
+LC L +Q +P K + ++ +N +NF+ G
Sbjct: 65 ALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLG 124
Query: 100 MNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQ 137
++ LFE+ L +V + LL L A G++
Sbjct: 125 VDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVE 162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,681,179
Number of Sequences: 37866
Number of extensions: 572736
Number of successful extensions: 1237
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1144
Number of HSP's gapped (non-prelim): 60
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.