Guide to the Human Genome
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Search of human proteins with 4757980

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4757980 beta chimerin isoform 2 [Homo sapiens]
         (468 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4757980 beta chimerin isoform 2 [Homo sapiens]                     960   0.0  
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]            702   0.0  
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]          664   0.0  
gi|91106928 beta chimerin isoform 1 [Homo sapiens]                    575   e-164
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]          132   5e-31
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...   132   9e-31
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...   132   9e-31
gi|91208437 GEM interacting protein [Homo sapiens]                    132   9e-31
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]          130   2e-30
gi|188497642 ARHGAP15 [Homo sapiens]                                  130   2e-30
gi|23510413 sorting nexin 26 [Homo sapiens]                           130   3e-30
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                      130   3e-30
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                       130   3e-30
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]           130   3e-30
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]           128   1e-29
gi|156119615 myosin IXA [Homo sapiens]                                128   1e-29
gi|208022687 GTPase regulator associated with the focal adhesion...   128   1e-29
gi|7662208 GTPase regulator associated with the focal adhesion k...   128   1e-29
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]      127   2e-29
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ...   126   5e-29
gi|4505507 oligophrenin 1 [Homo sapiens]                              123   4e-28
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi...   122   9e-28
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi...   122   9e-28
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]                 120   3e-27
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]   120   3e-27
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]    120   3e-27
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap...   119   5e-27
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap...   119   5e-27
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]           118   1e-26
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]        117   2e-26

>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
          Length = 468

 Score =  960 bits (2481), Expect = 0.0
 Identities = 468/468 (100%), Positives = 468/468 (100%)

Query: 1   MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF 60
           MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
Sbjct: 1   MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF 60

Query: 61  HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF 120
           HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
Sbjct: 61  HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF 120

Query: 121 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT 180
           ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
Sbjct: 121 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT 180

Query: 181 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA 240
           NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
Sbjct: 181 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA 240

Query: 241 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE 300
           QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
Sbjct: 241 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE 300

Query: 301 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP 360
           IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
Sbjct: 301 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP 360

Query: 361 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN 420
           IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
Sbjct: 361 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN 420

Query: 421 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
           FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
Sbjct: 421 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score =  702 bits (1812), Expect = 0.0
 Identities = 333/453 (73%), Positives = 390/453 (86%), Gaps = 1/453 (0%)

Query: 17  DAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGV 76
           D +EY+PP+WKSYLYQLQQEAP P+RI C  EVENRPKYYGREFHG+ISRE AD+LL   
Sbjct: 7   DTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVA 66

Query: 77  EGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYI 136
           EG+Y++RESQRQPG YTLALRFG+QT N+RL++DGKHFVGEKRFESIHDLVTDGLITLYI
Sbjct: 67  EGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYI 126

Query: 137 ETKAAEYISKMTTNPIYEHIGYATLLREKVSRR-LSRSKNEPRKTNVTHEEHTAVEKISS 195
           ETKAAEYI+KMT NPIYEH+GY TL RE   ++ +   K    + + T ++  + ++++S
Sbjct: 127 ETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTS 186

Query: 196 LVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQ 255
           LVRRA L  N+    YEK HNFKVHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQ
Sbjct: 187 LVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQ 246

Query: 256 CSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVS 315
           CSK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVS
Sbjct: 247 CSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVS 306

Query: 316 GFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375
           GF++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++
Sbjct: 307 GFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIES 366

Query: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435
           AKI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTL
Sbjct: 367 AKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTL 426

Query: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
           MR PE   +  L+D+RYQ+L+V++LI+NED+LF
Sbjct: 427 MRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score =  664 bits (1713), Expect = 0.0
 Identities = 321/452 (71%), Positives = 371/452 (82%), Gaps = 25/452 (5%)

Query: 17  DAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGV 76
           D +EY+PP+WKSYLYQLQQEAP P+RI C  EVENRPKYYGREFHG+ISRE AD+LL   
Sbjct: 7   DTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVA 66

Query: 77  EGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYI 136
           EG+Y++RESQRQPG YTLALRFG+QT N+RL++DGKHFVGEKRFESIHDLVTDGLITLYI
Sbjct: 67  EGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYI 126

Query: 137 ETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSL 196
           ETKAAEYI+KMT NPIYEH+GY TL RE   ++      E      TH+E  +  +    
Sbjct: 127 ETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKE------THDERDSTGQDGVS 180

Query: 197 VRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQC 256
            +R                   VHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQC
Sbjct: 181 EKR-------------------VHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQC 221

Query: 257 SKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSG 316
           SK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVSG
Sbjct: 222 SKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSG 281

Query: 317 FTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAA 376
           F++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++A
Sbjct: 282 FSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESA 341

Query: 377 KISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM 436
           KI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTLM
Sbjct: 342 KIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLM 401

Query: 437 RPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
           R PE   +  L+D+RYQ+L+V++LI+NED+LF
Sbjct: 402 RSPELDAMAALNDIRYQRLVVELLIKNEDILF 433


>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
          Length = 332

 Score =  575 bits (1483), Expect = e-164
 Identities = 277/280 (98%), Positives = 278/280 (99%)

Query: 189 AVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC 248
           A  +ISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC
Sbjct: 53  ACSQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC 112

Query: 249 GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS 308
           GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS
Sbjct: 113 GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS 172

Query: 309 EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT 368
           EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT
Sbjct: 173 EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT 232

Query: 369 YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG 428
           YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG
Sbjct: 233 YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG 292

Query: 429 IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
           IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
Sbjct: 293 IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score =  132 bits (333), Expect = 5e-31
 Identities = 71/182 (39%), Positives = 106/182 (58%)

Query: 287  NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN 346
            N   P++VDIC + +E RGL+  G+YRV G    I  ++   ++     DI  + + D+N
Sbjct: 1158 NRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLN 1217

Query: 347  IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYL 406
            +I+  LK +FR LP P+ T D Y+ FI+A +  +  +RL+ +  ++  LP  HYETL++L
Sbjct: 1218 VISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFL 1277

Query: 407  MIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDV 466
              HLK V  N + N M   NL IVFGPTL+R  ED+    +  M  Q  IV+ LI++ D 
Sbjct: 1278 SAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDW 1337

Query: 467  LF 468
             F
Sbjct: 1338 FF 1339


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score =  132 bits (331), Expect = 9e-31
 Identities = 68/190 (35%), Positives = 116/190 (61%), Gaps = 2/190 (1%)

Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332
           +V+ C L  L +   ++ P  V  CIR +EARGL  +GLYR+SG    I+ ++   D D 
Sbjct: 325 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 383

Query: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392
           E+ D+    + D+++ITGALKL+FR+LP P+  +  + +FI A K+ +   R   V +++
Sbjct: 384 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 443

Query: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 452
             LP  +++TLR L  HL +V  + + N M+ +++ IVFGPTL+RP  + T   +  M +
Sbjct: 444 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPM-TMVF 502

Query: 453 QKLIVQILIE 462
           Q  +V+++++
Sbjct: 503 QNQVVELILQ 512


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score =  132 bits (331), Expect = 9e-31
 Identities = 68/190 (35%), Positives = 116/190 (61%), Gaps = 2/190 (1%)

Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332
           +V+ C L  L +   ++ P  V  CIR +EARGL  +GLYR+SG    I+ ++   D D 
Sbjct: 352 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 410

Query: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392
           E+ D+    + D+++ITGALKL+FR+LP P+  +  + +FI A K+ +   R   V +++
Sbjct: 411 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 470

Query: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 452
             LP  +++TLR L  HL +V  + + N M+ +++ IVFGPTL+RP  + T   +  M +
Sbjct: 471 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPM-TMVF 529

Query: 453 QKLIVQILIE 462
           Q  +V+++++
Sbjct: 530 QNQVVELILQ 539


>gi|91208437 GEM interacting protein [Homo sapiens]
          Length = 970

 Score =  132 bits (331), Expect = 9e-31
 Identities = 90/275 (32%), Positives = 136/275 (49%), Gaps = 28/275 (10%)

Query: 213 KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 271
           +TH  +    RGP  C  C  FM      G  C +C L  HK+C + +   C    L   
Sbjct: 492 QTHQLR--RLRGPAKCRECEAFM----VSGTECEECFLTCHKRCLETLLILCGHRRLPAR 545

Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331
             ++  D   L +    + P VV  C  EIE R L  +G+YRVSG    +E +  AF+  
Sbjct: 546 TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENG 605

Query: 332 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNAD--------- 382
               ++S N   D++ +   LK + ++L  PVI +  Y  FI  AK  +AD         
Sbjct: 606 RALVELSGNSPHDVSSV---LKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPS 662

Query: 383 ---ERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPP 439
              E + ++  +L+ LP ++Y TLR+L+ HL +V     +N M+A NLGIVFGPTL+RPP
Sbjct: 663 PSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPP 722

Query: 440 EDS------TLTTLHDMRYQKLIVQILIENEDVLF 468
           +         +T L D  +Q  +V+ LI + + +F
Sbjct: 723 DGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score =  130 bits (328), Expect = 2e-30
 Identities = 75/227 (33%), Positives = 121/227 (53%), Gaps = 24/227 (10%)

Query: 249  GLNVHKQCSKHVPN-------DCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREI 301
            G+N+ K+  K  P        +CQP                    N + P++V  C R +
Sbjct: 794  GINIIKKNKKAAPRAFGVRLEECQP-----------------ATENQRVPLIVAACCRIV 836

Query: 302  EARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPI 361
            EARGL+S G+YRV G    +  ++   +R     ++    + D+N+I+  LK +FR LP 
Sbjct: 837  EARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPE 896

Query: 362  PVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNF 421
            P+ T D Y+ FI+A +I +A ER+  + +++  LP  +YETL++L+ HLK +  + + N 
Sbjct: 897  PLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNK 956

Query: 422  MNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
            M   NL +VFGPTL+R  ED+    +  M  +  IV+ LI++ D  F
Sbjct: 957  MEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFF 1003


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score =  130 bits (328), Expect = 2e-30
 Identities = 68/211 (32%), Positives = 123/211 (58%), Gaps = 9/211 (4%)

Query: 265 QPDLKRIKK-------VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGF 317
           +P LK +++       ++   L  + +  N+  P  V  CI  +E RGL  +G+YRVSG 
Sbjct: 262 RPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGN 321

Query: 318 TEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAK 377
              I+ ++   +++ EK ++  + + DI+++TGALK++FR+LP P+  Y  + +F++A K
Sbjct: 322 LATIQKLRFIVNQE-EKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIK 380

Query: 378 ISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMR 437
             + + R+EAV  ++  LPP + +T++ L  HL K+      N M+ ++LGIVFGPTL+R
Sbjct: 381 KQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLR 440

Query: 438 PPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
              ++    +H M YQ  I ++++     +F
Sbjct: 441 AENETGNMAIH-MVYQNQIAELMLSEYSKIF 470


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score =  130 bits (327), Expect = 3e-30
 Identities = 70/202 (34%), Positives = 113/202 (55%), Gaps = 6/202 (2%)

Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331
           ++V+ CDL   +       P V+  C   IEA G+  +G+YR+SG + +I+ ++  FD +
Sbjct: 310 QRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVV-DGIYRLSGVSSNIQRLRHEFDSE 368

Query: 332 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEV 391
                       DI+ ++   KLYFR+LP P++TY  Y KF +A  +   +ERL  VH+V
Sbjct: 369 RIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDV 428

Query: 392 LMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTL-----TT 446
           +  LPP HY TL YL+ HL ++  +  +  M+A NL IV+ P L+R  E  ++       
Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488

Query: 447 LHDMRYQKLIVQILIENEDVLF 468
             ++R Q ++V+ L+ + DVLF
Sbjct: 489 FREVRVQSVVVEFLLTHVDVLF 510


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score =  130 bits (326), Expect = 3e-30
 Identities = 92/312 (29%), Positives = 155/312 (49%), Gaps = 31/312 (9%)

Query: 162  LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT 221
            L ++ +R  +++  EP K +   ++    E       RA   HN         H F  + 
Sbjct: 1595 LLDEFTRGYTKNDFEPVKQSKAQKKKRKQE-------RAVQEHNG--------HVFASYQ 1639

Query: 222  FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC--------QPDLKRIKK 273
               P  CE C +++W L+ + + CS C +  HK+C   + + C        +P ++    
Sbjct: 1640 VSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHF 1698

Query: 274  VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 333
              C D  T  KA     P+V++  +  +E  GL +EGLYR SG      +++ A   D  
Sbjct: 1699 GVCVDSLTSDKA---SVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD-- 1753

Query: 334  KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLM 393
             A +    +P I+ ITG LK + R+LP P++T+  Y  F+ A ++    E+L A++ VL 
Sbjct: 1754 PAAVKLENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLE 1812

Query: 394  LLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMRY 452
             LP A++ +L  L+ HL KV + E  N M+   L I+F P L+R P++S  LT++ D+  
Sbjct: 1813 HLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLK 1872

Query: 453  QKLIVQILIENE 464
                V++LI+ +
Sbjct: 1873 ITTCVEMLIKEQ 1884


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score =  130 bits (326), Expect = 3e-30
 Identities = 92/312 (29%), Positives = 155/312 (49%), Gaps = 31/312 (9%)

Query: 162  LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT 221
            L ++ +R  +++  EP K +   ++    E       RA   HN         H F  + 
Sbjct: 1595 LLDEFTRGYTKNDFEPVKQSKAQKKKRKQE-------RAVQEHNG--------HVFASYQ 1639

Query: 222  FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC--------QPDLKRIKK 273
               P  CE C +++W L+ + + CS C +  HK+C   + + C        +P ++    
Sbjct: 1640 VSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHF 1698

Query: 274  VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 333
              C D  T  KA     P+V++  +  +E  GL +EGLYR SG      +++ A   D  
Sbjct: 1699 GVCVDSLTSDKA---SVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD-- 1753

Query: 334  KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLM 393
             A +    +P I+ ITG LK + R+LP P++T+  Y  F+ A ++    E+L A++ VL 
Sbjct: 1754 PAAVKLENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLE 1812

Query: 394  LLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMRY 452
             LP A++ +L  L+ HL KV + E  N M+   L I+F P L+R P++S  LT++ D+  
Sbjct: 1813 HLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLK 1872

Query: 453  QKLIVQILIENE 464
                V++LI+ +
Sbjct: 1873 ITTCVEMLIKEQ 1884


>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
          Length = 786

 Score =  130 bits (326), Expect = 3e-30
 Identities = 68/178 (38%), Positives = 108/178 (60%), Gaps = 3/178 (1%)

Query: 293 VVDICIREIEARGLKSEGLYRVSGFTEHIEDV-KMAFD-RDGEKADISANVYPDINIITG 350
           ++  CI  +E RG+  +GLYRV G +  ++ +  M  D +   + D+  +   ++  IT 
Sbjct: 398 IIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITS 457

Query: 351 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 410
           ALK Y R LP P++TY+ +  FI  AK  + + R+ A+H ++  LP  + E L  L+ HL
Sbjct: 458 ALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHL 517

Query: 411 KKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
             V+ + K N M   NLG+VFGPTLMRP E+ T+  L D+++Q ++V+ILIEN + +F
Sbjct: 518 TNVSNHSKQNLMTVANLGVVFGPTLMRPQEE-TVAALMDLKFQNIVVEILIENHEKIF 574


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score =  128 bits (322), Expect = 1e-29
 Identities = 66/189 (34%), Positives = 120/189 (63%), Gaps = 3/189 (1%)

Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332
           +V+  +L  L +  N   P  V +CI  +E  GL  +G+YRVSG    I+ ++ A + D 
Sbjct: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710

Query: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392
           EK D++ + + DI++ITGALK++FR+LP P+ T++ ++ F++A K     +R+ AV +++
Sbjct: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769

Query: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 452
             LP  + +T++ L  HL++V  N + N M  +++ IVFGPTL++P +++    +H + Y
Sbjct: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828

Query: 453 QKLIVQILI 461
           Q  IV++++
Sbjct: 829 QNQIVELIL 837


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/250 (30%), Positives = 127/250 (50%), Gaps = 8/250 (3%)

Query: 215  HNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQP--DLKRIK 272
            H FK   +  P +CEYC++ +W +    V C  C    HK+C       C    D +   
Sbjct: 2000 HIFKATQYSIPTYCEYCSSLIWIMDRASV-CKLCKYACHKKCCLKTTAKCSKKYDPELSS 2058

Query: 273  KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332
            + +  +L+ L     T  P+VV+  I  IE  GL +EG+YR SG T  I++++   D D 
Sbjct: 2059 RQFGVELSRLTSEDRTV-PLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117

Query: 333  EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392
            E  ++      +I++I    K + RDLP P++T++ Y +F+ A  +    E +  V+ V+
Sbjct: 2118 ESVNLDDY---NIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVI 2174

Query: 393  MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMR 451
              L   H  TL  L+ HL ++ + E  N M+A  L IVF P ++R P+ +  L ++ D+ 
Sbjct: 2175 DQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDIS 2234

Query: 452  YQKLIVQILI 461
                 V++++
Sbjct: 2235 KTTTCVELIV 2244


>gi|208022687 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform b [Homo sapiens]
          Length = 759

 Score =  128 bits (321), Expect = 1e-29
 Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%)

Query: 293 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 345
           ++  CI  +E RG+  +GLYR+ G    ++       D K A + +    DI A    +I
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446

Query: 346 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 405
             IT ALK Y R LP P++ Y     FI AAK+ N + R+  +H ++  LP  + + L+ 
Sbjct: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506

Query: 406 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 465
           LM HL  V  N K N M   NLG+VFGPTL+RP E+ T+  + D+++Q ++++ILIEN +
Sbjct: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565

Query: 466 VLF 468
            +F
Sbjct: 566 KIF 568


>gi|7662208 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform a [Homo sapiens]
          Length = 814

 Score =  128 bits (321), Expect = 1e-29
 Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%)

Query: 293 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 345
           ++  CI  +E RG+  +GLYR+ G    ++       D K A + +    DI A    +I
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446

Query: 346 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 405
             IT ALK Y R LP P++ Y     FI AAK+ N + R+  +H ++  LP  + + L+ 
Sbjct: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506

Query: 406 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 465
           LM HL  V  N K N M   NLG+VFGPTL+RP E+ T+  + D+++Q ++++ILIEN +
Sbjct: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565

Query: 466 VLF 468
            +F
Sbjct: 566 KIF 568


>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
          Length = 1136

 Score =  127 bits (319), Expect = 2e-29
 Identities = 89/282 (31%), Positives = 147/282 (52%), Gaps = 34/282 (12%)

Query: 213 KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 271
           +TH  ++   R P  C  C ++++    QG  C +C L  HK+C + +   C    L+  
Sbjct: 701 RTH--RLRKLRTPAKCRECNSYVY---FQGAECEECCLACHKKCLETLAIQCGHKKLQGR 755

Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331
            +++  D +   ++     P +V  C+ EIE R L+++G+YRV+G    +E +  AF+  
Sbjct: 756 LQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENG 815

Query: 332 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADE-------- 383
            E  ++S     DI+ +   LKLY R LP P+I++  Y + +  AK S   E        
Sbjct: 816 KELVELSQASPHDISNV---LKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASR 872

Query: 384 ------RLEAV--------HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGI 429
                   EAV         E+L  LPP +  +L+YL+ HL+++   E+DN M   NLGI
Sbjct: 873 GRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGI 932

Query: 430 VFGPTLMRP-PEDST--LTTLHDMRYQKLIVQILIENEDVLF 468
           VFGPTL+RP P ++T  L++L D  +Q  +++ LI +  ++F
Sbjct: 933 VFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVF 974


>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
            sapiens]
          Length = 1499

 Score =  126 bits (316), Expect = 5e-29
 Identities = 69/184 (37%), Positives = 112/184 (60%), Gaps = 4/184 (2%)

Query: 279  LTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADIS 338
            LTT+V       P+ ++ CI  IEA GL +EG+YRVSG    +E ++  FD+D    D++
Sbjct: 1251 LTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HNLDLA 1308

Query: 339  ANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPA 398
               +  +N + GA+K +F +LP P++ Y+     ++A KI++ +++L A+ EVL   P  
Sbjct: 1309 EKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKE 1367

Query: 399  HYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQ 458
            ++E  +Y++ HL KV+ N K N M +ENL I F PTLMR P+ ST+  L   R  + I++
Sbjct: 1368 NHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQTIIE 1426

Query: 459  ILIE 462
            + I+
Sbjct: 1427 LFIQ 1430


>gi|4505507 oligophrenin 1 [Homo sapiens]
          Length = 802

 Score =  123 bits (308), Expect = 4e-28
 Identities = 67/168 (39%), Positives = 100/168 (59%), Gaps = 2/168 (1%)

Query: 297 CIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISA-NVYPDINIITGALKLY 355
           CI  IE +G+K+EGLYR  G    ++ +  AF       D+   N   DI  IT +LK Y
Sbjct: 393 CINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFY 452

Query: 356 FRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 415
            R+L  PV+TY  + + + AAK  N D RL A+H ++  LP  + E L  L+ HL  V  
Sbjct: 453 LRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCE 512

Query: 416 NEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIEN 463
           + K+N M   N+G++FGPTLMR  ED T+  + ++++Q ++V+ILIE+
Sbjct: 513 HSKENLMTPSNMGVIFGPTLMRAQED-TVAAMMNIKFQNIVVEILIEH 559


>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
          Length = 1502

 Score =  122 bits (305), Expect = 9e-28
 Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%)

Query: 291  PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 350
            P+ V+ C+  IE  GL +EGLYRVSG     ++++  FD+D     +S  V   +N + G
Sbjct: 1275 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1332

Query: 351  ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 410
            ALK +F DLP P+I Y  + + ++AAKI +  ERL A+ E++    P +Y+  RY++ HL
Sbjct: 1333 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1392

Query: 411  KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 458
             +V+   K N M A+NL I F PTLMRP     E  + T +H    +  I Q
Sbjct: 1393 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1444


>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
          Length = 1501

 Score =  122 bits (305), Expect = 9e-28
 Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%)

Query: 291  PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 350
            P+ V+ C+  IE  GL +EGLYRVSG     ++++  FD+D     +S  V   +N + G
Sbjct: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331

Query: 351  ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 410
            ALK +F DLP P+I Y  + + ++AAKI +  ERL A+ E++    P +Y+  RY++ HL
Sbjct: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391

Query: 411  KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 458
             +V+   K N M A+NL I F PTLMRP     E  + T +H    +  I Q
Sbjct: 1392 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1443


>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
          Length = 1261

 Score =  120 bits (301), Expect = 3e-27
 Identities = 89/302 (29%), Positives = 141/302 (46%), Gaps = 47/302 (15%)

Query: 195 SLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHK 254
           +L+ +AALTH             K    R P  C  C   +   + QGV C +C L  H+
Sbjct: 604 TLMSKAALTH-------------KFRKLRSPTKCRDCEGIV---VFQGVECEECLLVCHR 647

Query: 255 QCSKHVPNDC-QPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYR 313
           +C +++   C    L     ++  + T + K      P ++ IC  EIE R L  +G+YR
Sbjct: 648 KCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYR 707

Query: 314 VSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFI 373
           V G     E +  A +      DIS     DI      LKLY R LP P I +  Y +FI
Sbjct: 708 VCGNKIKTEKLCQALENGMHLVDISEFSSHDI---CDVLKLYLRQLPEPFILFRLYKEFI 764

Query: 374 DAAK-ISNADERLEAVH-----------------------EVLMLLPPAHYETLRYLMIH 409
           D AK I + +E  E                          ++L  LP +++ +L +L++H
Sbjct: 765 DLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVH 824

Query: 410 LKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS---TLTTLHDMRYQKLIVQILIENEDV 466
           LK+V  + ++N MN++NLG++FGP+L+RP   +   T+++L +   Q  +V+ LI     
Sbjct: 825 LKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAPITISSLAEYSNQARLVEFLITYSQK 884

Query: 467 LF 468
           +F
Sbjct: 885 IF 886


>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
          Length = 2087

 Score =  120 bits (300), Expect = 3e-27
 Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%)

Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331
           ++V+ CDL   +     + P V+  C   IE  G+  +G+YR+SG   +I+ ++  FD +
Sbjct: 367 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 425

Query: 332 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 390
               D++   Y  DI+ +    KLYFR+LP P++TY  Y KF DA   +  +ERL  +H+
Sbjct: 426 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 484

Query: 391 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 445
           V+  LPP HY TL +LM HL  +        M+A+NL IV+ P L+R  +      S   
Sbjct: 485 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 544

Query: 446 TLHDMRYQKLIVQILIENEDVLF 468
              ++R Q ++V+ ++ + DVLF
Sbjct: 545 AFMEVRIQSVVVEFILNHVDVLF 567


>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
          Length = 1738

 Score =  120 bits (300), Expect = 3e-27
 Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%)

Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331
           ++V+ CDL   +     + P V+  C   IE  G+  +G+YR+SG   +I+ ++  FD +
Sbjct: 18  ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 76

Query: 332 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 390
               D++   Y  DI+ +    KLYFR+LP P++TY  Y KF DA   +  +ERL  +H+
Sbjct: 77  -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 135

Query: 391 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 445
           V+  LPP HY TL +LM HL  +        M+A+NL IV+ P L+R  +      S   
Sbjct: 136 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 195

Query: 446 TLHDMRYQKLIVQILIENEDVLF 468
              ++R Q ++V+ ++ + DVLF
Sbjct: 196 AFMEVRIQSVVVEFILNHVDVLF 218


>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
           sapiens]
          Length = 731

 Score =  119 bits (299), Expect = 5e-27
 Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%)

Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 330
           +V+ C L +L +      P  + +CI  ++ RGL  +G+YRVSG    ++ ++   DR  
Sbjct: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578

Query: 331 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375
               DG            + D+ +  + DI+++TGALKL+ R+LP P++       F  A
Sbjct: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 638

Query: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435
             +S +++ L  + E++  +P  +++TLRYL+ HL +V  +   N M   NLGIVFGPTL
Sbjct: 639 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 698

Query: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
            RP ++++    H + Y   +VQ+++ N   LF
Sbjct: 699 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 730


>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
           sapiens]
          Length = 547

 Score =  119 bits (299), Expect = 5e-27
 Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%)

Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 330
           +V+ C L +L +      P  + +CI  ++ RGL  +G+YRVSG    ++ ++   DR  
Sbjct: 335 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 394

Query: 331 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375
               DG            + D+ +  + DI+++TGALKL+ R+LP P++       F  A
Sbjct: 395 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 454

Query: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435
             +S +++ L  + E++  +P  +++TLRYL+ HL +V  +   N M   NLGIVFGPTL
Sbjct: 455 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 514

Query: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
            RP ++++    H + Y   +VQ+++ N   LF
Sbjct: 515 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 546


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score =  118 bits (295), Expect = 1e-26
 Identities = 66/206 (32%), Positives = 110/206 (53%), Gaps = 8/206 (3%)

Query: 269 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 328
           K     + CDLT  +++     P V+  C   IE  G+  +G+YR+SG T +I+ ++  F
Sbjct: 13  KGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIV-DGIYRLSGVTSNIQRLRQEF 71

Query: 329 DRDGEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEA 387
             D +  D++  VY  DI+ +    KLYFR+LP P++TY+ Y KF +A      + +L  
Sbjct: 72  GSD-QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLAR 130

Query: 388 VHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTL 447
           +  V+  LPP+HY TL YL+ HL  +        M+A NL +V+ P L+R  E       
Sbjct: 131 IQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCN 190

Query: 448 HD-----MRYQKLIVQILIENEDVLF 468
            D     +R Q+++++ ++ + D +F
Sbjct: 191 GDAAFLAVRVQQVVIEFILNHVDQIF 216


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score =  117 bits (293), Expect = 2e-26
 Identities = 62/167 (37%), Positives = 95/167 (56%), Gaps = 1/167 (0%)

Query: 274  VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 333
            V+   +  + K   ++ P +V  C+ EIE RG++  G+YRVSG    I+ +K AFD + +
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066

Query: 334  KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLM 393
               +  +   D+N I G LKLYFR+LP P+ T + Y  F +   +S+   +   +  +L+
Sbjct: 1067 DVSVMMSEM-DVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLL 1125

Query: 394  LLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE 440
             LP A+  T  +L+ HLK+V   E  N M+  NL  VFGPTL+RP E
Sbjct: 1126 SLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSE 1172


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,759,383
Number of Sequences: 37866
Number of extensions: 793759
Number of successful extensions: 3081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 110
Number of HSP's that attempted gapping in prelim test: 2614
Number of HSP's gapped (non-prelim): 401
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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