BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4757980 beta chimerin isoform 2 [Homo sapiens] (468 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4757980 beta chimerin isoform 2 [Homo sapiens] 960 0.0 gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 702 0.0 gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 664 0.0 gi|91106928 beta chimerin isoform 1 [Homo sapiens] 575 e-164 gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 132 5e-31 gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 132 9e-31 gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 132 9e-31 gi|91208437 GEM interacting protein [Homo sapiens] 132 9e-31 gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 130 2e-30 gi|188497642 ARHGAP15 [Homo sapiens] 130 2e-30 gi|23510413 sorting nexin 26 [Homo sapiens] 130 3e-30 gi|194272142 myosin IXB isoform 2 [Homo sapiens] 130 3e-30 gi|33356170 myosin IXB isoform 1 [Homo sapiens] 130 3e-30 gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 130 3e-30 gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 128 1e-29 gi|156119615 myosin IXA [Homo sapiens] 128 1e-29 gi|208022687 GTPase regulator associated with the focal adhesion... 128 1e-29 gi|7662208 GTPase regulator associated with the focal adhesion k... 128 1e-29 gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 127 2e-29 gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 126 5e-29 gi|4505507 oligophrenin 1 [Homo sapiens] 123 4e-28 gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 122 9e-28 gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 122 9e-28 gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens] 120 3e-27 gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 120 3e-27 gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 120 3e-27 gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 119 5e-27 gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 119 5e-27 gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 118 1e-26 gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 117 2e-26 >gi|4757980 beta chimerin isoform 2 [Homo sapiens] Length = 468 Score = 960 bits (2481), Expect = 0.0 Identities = 468/468 (100%), Positives = 468/468 (100%) Query: 1 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF 60 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF Sbjct: 1 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF 60 Query: 61 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF 120 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF Sbjct: 61 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF 120 Query: 121 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT 180 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT Sbjct: 121 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT 180 Query: 181 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA 240 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA Sbjct: 181 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA 240 Query: 241 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE 300 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE Sbjct: 241 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE 300 Query: 301 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP 360 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP Sbjct: 301 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP 360 Query: 361 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN 420 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN Sbjct: 361 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN 420 Query: 421 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF Sbjct: 421 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 >gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] Length = 459 Score = 702 bits (1812), Expect = 0.0 Identities = 333/453 (73%), Positives = 390/453 (86%), Gaps = 1/453 (0%) Query: 17 DAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGV 76 D +EY+PP+WKSYLYQLQQEAP P+RI C EVENRPKYYGREFHG+ISRE AD+LL Sbjct: 7 DTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVA 66 Query: 77 EGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYI 136 EG+Y++RESQRQPG YTLALRFG+QT N+RL++DGKHFVGEKRFESIHDLVTDGLITLYI Sbjct: 67 EGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYI 126 Query: 137 ETKAAEYISKMTTNPIYEHIGYATLLREKVSRR-LSRSKNEPRKTNVTHEEHTAVEKISS 195 ETKAAEYI+KMT NPIYEH+GY TL RE ++ + K + + T ++ + ++++S Sbjct: 127 ETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTS 186 Query: 196 LVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQ 255 LVRRA L N+ YEK HNFKVHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQ Sbjct: 187 LVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQ 246 Query: 256 CSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVS 315 CSK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVS Sbjct: 247 CSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVS 306 Query: 316 GFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375 GF++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++ Sbjct: 307 GFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIES 366 Query: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435 AKI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTL Sbjct: 367 AKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTL 426 Query: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 MR PE + L+D+RYQ+L+V++LI+NED+LF Sbjct: 427 MRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459 >gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] Length = 433 Score = 664 bits (1713), Expect = 0.0 Identities = 321/452 (71%), Positives = 371/452 (82%), Gaps = 25/452 (5%) Query: 17 DAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGV 76 D +EY+PP+WKSYLYQLQQEAP P+RI C EVENRPKYYGREFHG+ISRE AD+LL Sbjct: 7 DTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVA 66 Query: 77 EGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYI 136 EG+Y++RESQRQPG YTLALRFG+QT N+RL++DGKHFVGEKRFESIHDLVTDGLITLYI Sbjct: 67 EGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYI 126 Query: 137 ETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSL 196 ETKAAEYI+KMT NPIYEH+GY TL RE ++ E TH+E + + Sbjct: 127 ETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKE------THDERDSTGQDGVS 180 Query: 197 VRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQC 256 +R VHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQC Sbjct: 181 EKR-------------------VHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQC 221 Query: 257 SKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSG 316 SK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVSG Sbjct: 222 SKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSG 281 Query: 317 FTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAA 376 F++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++A Sbjct: 282 FSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESA 341 Query: 377 KISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM 436 KI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTLM Sbjct: 342 KIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLM 401 Query: 437 RPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 R PE + L+D+RYQ+L+V++LI+NED+LF Sbjct: 402 RSPELDAMAALNDIRYQRLVVELLIKNEDILF 433 >gi|91106928 beta chimerin isoform 1 [Homo sapiens] Length = 332 Score = 575 bits (1483), Expect = e-164 Identities = 277/280 (98%), Positives = 278/280 (99%) Query: 189 AVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC 248 A +ISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC Sbjct: 53 ACSQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC 112 Query: 249 GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS 308 GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS Sbjct: 113 GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS 172 Query: 309 EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT 368 EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT Sbjct: 173 EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT 232 Query: 369 YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG 428 YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG Sbjct: 233 YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG 292 Query: 429 IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF Sbjct: 293 IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332 >gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] Length = 1958 Score = 132 bits (333), Expect = 5e-31 Identities = 71/182 (39%), Positives = 106/182 (58%) Query: 287 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN 346 N P++VDIC + +E RGL+ G+YRV G I ++ ++ DI + + D+N Sbjct: 1158 NRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLN 1217 Query: 347 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYL 406 +I+ LK +FR LP P+ T D Y+ FI+A + + +RL+ + ++ LP HYETL++L Sbjct: 1218 VISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFL 1277 Query: 407 MIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDV 466 HLK V N + N M NL IVFGPTL+R ED+ + M Q IV+ LI++ D Sbjct: 1278 SAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDW 1337 Query: 467 LF 468 F Sbjct: 1338 FF 1339 >gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sapiens] Length = 521 Score = 132 bits (331), Expect = 9e-31 Identities = 68/190 (35%), Positives = 116/190 (61%), Gaps = 2/190 (1%) Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332 +V+ C L L + ++ P V CIR +EARGL +GLYR+SG I+ ++ D D Sbjct: 325 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 383 Query: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392 E+ D+ + D+++ITGALKL+FR+LP P+ + + +FI A K+ + R V +++ Sbjct: 384 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 443 Query: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 452 LP +++TLR L HL +V + + N M+ +++ IVFGPTL+RP + T + M + Sbjct: 444 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPM-TMVF 502 Query: 453 QKLIVQILIE 462 Q +V+++++ Sbjct: 503 QNQVVELILQ 512 >gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens] Length = 548 Score = 132 bits (331), Expect = 9e-31 Identities = 68/190 (35%), Positives = 116/190 (61%), Gaps = 2/190 (1%) Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332 +V+ C L L + ++ P V CIR +EARGL +GLYR+SG I+ ++ D D Sbjct: 352 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 410 Query: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392 E+ D+ + D+++ITGALKL+FR+LP P+ + + +FI A K+ + R V +++ Sbjct: 411 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 470 Query: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 452 LP +++TLR L HL +V + + N M+ +++ IVFGPTL+RP + T + M + Sbjct: 471 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPM-TMVF 529 Query: 453 QKLIVQILIE 462 Q +V+++++ Sbjct: 530 QNQVVELILQ 539 >gi|91208437 GEM interacting protein [Homo sapiens] Length = 970 Score = 132 bits (331), Expect = 9e-31 Identities = 90/275 (32%), Positives = 136/275 (49%), Gaps = 28/275 (10%) Query: 213 KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 271 +TH + RGP C C FM G C +C L HK+C + + C L Sbjct: 492 QTHQLR--RLRGPAKCRECEAFM----VSGTECEECFLTCHKRCLETLLILCGHRRLPAR 545 Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331 ++ D L + + P VV C EIE R L +G+YRVSG +E + AF+ Sbjct: 546 TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENG 605 Query: 332 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNAD--------- 382 ++S N D++ + LK + ++L PVI + Y FI AK +AD Sbjct: 606 RALVELSGNSPHDVSSV---LKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPS 662 Query: 383 ---ERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPP 439 E + ++ +L+ LP ++Y TLR+L+ HL +V +N M+A NLGIVFGPTL+RPP Sbjct: 663 PSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPP 722 Query: 440 EDS------TLTTLHDMRYQKLIVQILIENEDVLF 468 + +T L D +Q +V+ LI + + +F Sbjct: 723 DGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757 >gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] Length = 1397 Score = 130 bits (328), Expect = 2e-30 Identities = 75/227 (33%), Positives = 121/227 (53%), Gaps = 24/227 (10%) Query: 249 GLNVHKQCSKHVPN-------DCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREI 301 G+N+ K+ K P +CQP N + P++V C R + Sbjct: 794 GINIIKKNKKAAPRAFGVRLEECQP-----------------ATENQRVPLIVAACCRIV 836 Query: 302 EARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPI 361 EARGL+S G+YRV G + ++ +R ++ + D+N+I+ LK +FR LP Sbjct: 837 EARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPE 896 Query: 362 PVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNF 421 P+ T D Y+ FI+A +I +A ER+ + +++ LP +YETL++L+ HLK + + + N Sbjct: 897 PLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNK 956 Query: 422 MNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 M NL +VFGPTL+R ED+ + M + IV+ LI++ D F Sbjct: 957 MEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFF 1003 >gi|188497642 ARHGAP15 [Homo sapiens] Length = 475 Score = 130 bits (328), Expect = 2e-30 Identities = 68/211 (32%), Positives = 123/211 (58%), Gaps = 9/211 (4%) Query: 265 QPDLKRIKK-------VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGF 317 +P LK +++ ++ L + + N+ P V CI +E RGL +G+YRVSG Sbjct: 262 RPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGN 321 Query: 318 TEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAK 377 I+ ++ +++ EK ++ + + DI+++TGALK++FR+LP P+ Y + +F++A K Sbjct: 322 LATIQKLRFIVNQE-EKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIK 380 Query: 378 ISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMR 437 + + R+EAV ++ LPP + +T++ L HL K+ N M+ ++LGIVFGPTL+R Sbjct: 381 KQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLR 440 Query: 438 PPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 ++ +H M YQ I ++++ +F Sbjct: 441 AENETGNMAIH-MVYQNQIAELMLSEYSKIF 470 >gi|23510413 sorting nexin 26 [Homo sapiens] Length = 1126 Score = 130 bits (327), Expect = 3e-30 Identities = 70/202 (34%), Positives = 113/202 (55%), Gaps = 6/202 (2%) Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331 ++V+ CDL + P V+ C IEA G+ +G+YR+SG + +I+ ++ FD + Sbjct: 310 QRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVV-DGIYRLSGVSSNIQRLRHEFDSE 368 Query: 332 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEV 391 DI+ ++ KLYFR+LP P++TY Y KF +A + +ERL VH+V Sbjct: 369 RIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDV 428 Query: 392 LMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTL-----TT 446 + LPP HY TL YL+ HL ++ + + M+A NL IV+ P L+R E ++ Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488 Query: 447 LHDMRYQKLIVQILIENEDVLF 468 ++R Q ++V+ L+ + DVLF Sbjct: 489 FREVRVQSVVVEFLLTHVDVLF 510 >gi|194272142 myosin IXB isoform 2 [Homo sapiens] Length = 2022 Score = 130 bits (326), Expect = 3e-30 Identities = 92/312 (29%), Positives = 155/312 (49%), Gaps = 31/312 (9%) Query: 162 LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT 221 L ++ +R +++ EP K + ++ E RA HN H F + Sbjct: 1595 LLDEFTRGYTKNDFEPVKQSKAQKKKRKQE-------RAVQEHNG--------HVFASYQ 1639 Query: 222 FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC--------QPDLKRIKK 273 P CE C +++W L+ + + CS C + HK+C + + C +P ++ Sbjct: 1640 VSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHF 1698 Query: 274 VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 333 C D T KA P+V++ + +E GL +EGLYR SG +++ A D Sbjct: 1699 GVCVDSLTSDKA---SVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD-- 1753 Query: 334 KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLM 393 A + +P I+ ITG LK + R+LP P++T+ Y F+ A ++ E+L A++ VL Sbjct: 1754 PAAVKLENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLE 1812 Query: 394 LLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMRY 452 LP A++ +L L+ HL KV + E N M+ L I+F P L+R P++S LT++ D+ Sbjct: 1813 HLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLK 1872 Query: 453 QKLIVQILIENE 464 V++LI+ + Sbjct: 1873 ITTCVEMLIKEQ 1884 >gi|33356170 myosin IXB isoform 1 [Homo sapiens] Length = 2157 Score = 130 bits (326), Expect = 3e-30 Identities = 92/312 (29%), Positives = 155/312 (49%), Gaps = 31/312 (9%) Query: 162 LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT 221 L ++ +R +++ EP K + ++ E RA HN H F + Sbjct: 1595 LLDEFTRGYTKNDFEPVKQSKAQKKKRKQE-------RAVQEHNG--------HVFASYQ 1639 Query: 222 FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC--------QPDLKRIKK 273 P CE C +++W L+ + + CS C + HK+C + + C +P ++ Sbjct: 1640 VSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHF 1698 Query: 274 VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 333 C D T KA P+V++ + +E GL +EGLYR SG +++ A D Sbjct: 1699 GVCVDSLTSDKA---SVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD-- 1753 Query: 334 KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLM 393 A + +P I+ ITG LK + R+LP P++T+ Y F+ A ++ E+L A++ VL Sbjct: 1754 PAAVKLENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLE 1812 Query: 394 LLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMRY 452 LP A++ +L L+ HL KV + E N M+ L I+F P L+R P++S LT++ D+ Sbjct: 1813 HLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLK 1872 Query: 453 QKLIVQILIENE 464 V++LI+ + Sbjct: 1873 ITTCVEMLIKEQ 1884 >gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] Length = 786 Score = 130 bits (326), Expect = 3e-30 Identities = 68/178 (38%), Positives = 108/178 (60%), Gaps = 3/178 (1%) Query: 293 VVDICIREIEARGLKSEGLYRVSGFTEHIEDV-KMAFD-RDGEKADISANVYPDINIITG 350 ++ CI +E RG+ +GLYRV G + ++ + M D + + D+ + ++ IT Sbjct: 398 IIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITS 457 Query: 351 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 410 ALK Y R LP P++TY+ + FI AK + + R+ A+H ++ LP + E L L+ HL Sbjct: 458 ALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHL 517 Query: 411 KKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 V+ + K N M NLG+VFGPTLMRP E+ T+ L D+++Q ++V+ILIEN + +F Sbjct: 518 TNVSNHSKQNLMTVANLGVVFGPTLMRPQEE-TVAALMDLKFQNIVVEILIENHEKIF 574 >gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] Length = 846 Score = 128 bits (322), Expect = 1e-29 Identities = 66/189 (34%), Positives = 120/189 (63%), Gaps = 3/189 (1%) Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332 +V+ +L L + N P V +CI +E GL +G+YRVSG I+ ++ A + D Sbjct: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710 Query: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392 EK D++ + + DI++ITGALK++FR+LP P+ T++ ++ F++A K +R+ AV +++ Sbjct: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769 Query: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 452 LP + +T++ L HL++V N + N M +++ IVFGPTL++P +++ +H + Y Sbjct: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828 Query: 453 QKLIVQILI 461 Q IV++++ Sbjct: 829 QNQIVELIL 837 >gi|156119615 myosin IXA [Homo sapiens] Length = 2548 Score = 128 bits (321), Expect = 1e-29 Identities = 75/250 (30%), Positives = 127/250 (50%), Gaps = 8/250 (3%) Query: 215 HNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQP--DLKRIK 272 H FK + P +CEYC++ +W + V C C HK+C C D + Sbjct: 2000 HIFKATQYSIPTYCEYCSSLIWIMDRASV-CKLCKYACHKKCCLKTTAKCSKKYDPELSS 2058 Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332 + + +L+ L T P+VV+ I IE GL +EG+YR SG T I++++ D D Sbjct: 2059 RQFGVELSRLTSEDRTV-PLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117 Query: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392 E ++ +I++I K + RDLP P++T++ Y +F+ A + E + V+ V+ Sbjct: 2118 ESVNLDDY---NIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVI 2174 Query: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMR 451 L H TL L+ HL ++ + E N M+A L IVF P ++R P+ + L ++ D+ Sbjct: 2175 DQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDIS 2234 Query: 452 YQKLIVQILI 461 V++++ Sbjct: 2235 KTTTCVELIV 2244 >gi|208022687 GTPase regulator associated with the focal adhesion kinase pp125 isoform b [Homo sapiens] Length = 759 Score = 128 bits (321), Expect = 1e-29 Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%) Query: 293 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 345 ++ CI +E RG+ +GLYR+ G ++ D K A + + DI A +I Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446 Query: 346 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 405 IT ALK Y R LP P++ Y FI AAK+ N + R+ +H ++ LP + + L+ Sbjct: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506 Query: 406 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 465 LM HL V N K N M NLG+VFGPTL+RP E+ T+ + D+++Q ++++ILIEN + Sbjct: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565 Query: 466 VLF 468 +F Sbjct: 566 KIF 568 >gi|7662208 GTPase regulator associated with the focal adhesion kinase pp125 isoform a [Homo sapiens] Length = 814 Score = 128 bits (321), Expect = 1e-29 Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%) Query: 293 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 345 ++ CI +E RG+ +GLYR+ G ++ D K A + + DI A +I Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446 Query: 346 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 405 IT ALK Y R LP P++ Y FI AAK+ N + R+ +H ++ LP + + L+ Sbjct: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506 Query: 406 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 465 LM HL V N K N M NLG+VFGPTL+RP E+ T+ + D+++Q ++++ILIEN + Sbjct: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565 Query: 466 VLF 468 +F Sbjct: 566 KIF 568 >gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] Length = 1136 Score = 127 bits (319), Expect = 2e-29 Identities = 89/282 (31%), Positives = 147/282 (52%), Gaps = 34/282 (12%) Query: 213 KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 271 +TH ++ R P C C ++++ QG C +C L HK+C + + C L+ Sbjct: 701 RTH--RLRKLRTPAKCRECNSYVY---FQGAECEECCLACHKKCLETLAIQCGHKKLQGR 755 Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331 +++ D + ++ P +V C+ EIE R L+++G+YRV+G +E + AF+ Sbjct: 756 LQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENG 815 Query: 332 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADE-------- 383 E ++S DI+ + LKLY R LP P+I++ Y + + AK S E Sbjct: 816 KELVELSQASPHDISNV---LKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASR 872 Query: 384 ------RLEAV--------HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGI 429 EAV E+L LPP + +L+YL+ HL+++ E+DN M NLGI Sbjct: 873 GRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGI 932 Query: 430 VFGPTLMRP-PEDST--LTTLHDMRYQKLIVQILIENEDVLF 468 VFGPTL+RP P ++T L++L D +Q +++ LI + ++F Sbjct: 933 VFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVF 974 >gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo sapiens] Length = 1499 Score = 126 bits (316), Expect = 5e-29 Identities = 69/184 (37%), Positives = 112/184 (60%), Gaps = 4/184 (2%) Query: 279 LTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADIS 338 LTT+V P+ ++ CI IEA GL +EG+YRVSG +E ++ FD+D D++ Sbjct: 1251 LTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HNLDLA 1308 Query: 339 ANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPA 398 + +N + GA+K +F +LP P++ Y+ ++A KI++ +++L A+ EVL P Sbjct: 1309 EKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKE 1367 Query: 399 HYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQ 458 ++E +Y++ HL KV+ N K N M +ENL I F PTLMR P+ ST+ L R + I++ Sbjct: 1368 NHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQTIIE 1426 Query: 459 ILIE 462 + I+ Sbjct: 1427 LFIQ 1430 >gi|4505507 oligophrenin 1 [Homo sapiens] Length = 802 Score = 123 bits (308), Expect = 4e-28 Identities = 67/168 (39%), Positives = 100/168 (59%), Gaps = 2/168 (1%) Query: 297 CIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISA-NVYPDINIITGALKLY 355 CI IE +G+K+EGLYR G ++ + AF D+ N DI IT +LK Y Sbjct: 393 CINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFY 452 Query: 356 FRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 415 R+L PV+TY + + + AAK N D RL A+H ++ LP + E L L+ HL V Sbjct: 453 LRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCE 512 Query: 416 NEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIEN 463 + K+N M N+G++FGPTLMR ED T+ + ++++Q ++V+ILIE+ Sbjct: 513 HSKENLMTPSNMGVIFGPTLMRAQED-TVAAMMNIKFQNIVVEILIEH 559 >gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens] Length = 1502 Score = 122 bits (305), Expect = 9e-28 Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%) Query: 291 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 350 P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S V +N + G Sbjct: 1275 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1332 Query: 351 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 410 ALK +F DLP P+I Y + + ++AAKI + ERL A+ E++ P +Y+ RY++ HL Sbjct: 1333 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1392 Query: 411 KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 458 +V+ K N M A+NL I F PTLMRP E + T +H + I Q Sbjct: 1393 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1444 >gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens] Length = 1501 Score = 122 bits (305), Expect = 9e-28 Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%) Query: 291 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 350 P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S V +N + G Sbjct: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331 Query: 351 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 410 ALK +F DLP P+I Y + + ++AAKI + ERL A+ E++ P +Y+ RY++ HL Sbjct: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391 Query: 411 KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 458 +V+ K N M A+NL I F PTLMRP E + T +H + I Q Sbjct: 1392 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1443 >gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens] Length = 1261 Score = 120 bits (301), Expect = 3e-27 Identities = 89/302 (29%), Positives = 141/302 (46%), Gaps = 47/302 (15%) Query: 195 SLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHK 254 +L+ +AALTH K R P C C + + QGV C +C L H+ Sbjct: 604 TLMSKAALTH-------------KFRKLRSPTKCRDCEGIV---VFQGVECEECLLVCHR 647 Query: 255 QCSKHVPNDC-QPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYR 313 +C +++ C L ++ + T + K P ++ IC EIE R L +G+YR Sbjct: 648 KCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYR 707 Query: 314 VSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFI 373 V G E + A + DIS DI LKLY R LP P I + Y +FI Sbjct: 708 VCGNKIKTEKLCQALENGMHLVDISEFSSHDI---CDVLKLYLRQLPEPFILFRLYKEFI 764 Query: 374 DAAK-ISNADERLEAVH-----------------------EVLMLLPPAHYETLRYLMIH 409 D AK I + +E E ++L LP +++ +L +L++H Sbjct: 765 DLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVH 824 Query: 410 LKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS---TLTTLHDMRYQKLIVQILIENEDV 466 LK+V + ++N MN++NLG++FGP+L+RP + T+++L + Q +V+ LI Sbjct: 825 LKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAPITISSLAEYSNQARLVEFLITYSQK 884 Query: 467 LF 468 +F Sbjct: 885 IF 886 >gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] Length = 2087 Score = 120 bits (300), Expect = 3e-27 Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%) Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331 ++V+ CDL + + P V+ C IE G+ +G+YR+SG +I+ ++ FD + Sbjct: 367 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 425 Query: 332 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 390 D++ Y DI+ + KLYFR+LP P++TY Y KF DA + +ERL +H+ Sbjct: 426 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 484 Query: 391 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 445 V+ LPP HY TL +LM HL + M+A+NL IV+ P L+R + S Sbjct: 485 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 544 Query: 446 TLHDMRYQKLIVQILIENEDVLF 468 ++R Q ++V+ ++ + DVLF Sbjct: 545 AFMEVRIQSVVVEFILNHVDVLF 567 >gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] Length = 1738 Score = 120 bits (300), Expect = 3e-27 Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%) Query: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331 ++V+ CDL + + P V+ C IE G+ +G+YR+SG +I+ ++ FD + Sbjct: 18 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 76 Query: 332 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 390 D++ Y DI+ + KLYFR+LP P++TY Y KF DA + +ERL +H+ Sbjct: 77 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 135 Query: 391 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 445 V+ LPP HY TL +LM HL + M+A+NL IV+ P L+R + S Sbjct: 136 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 195 Query: 446 TLHDMRYQKLIVQILIENEDVLF 468 ++R Q ++V+ ++ + DVLF Sbjct: 196 AFMEVRIQSVVVEFILNHVDVLF 218 >gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sapiens] Length = 731 Score = 119 bits (299), Expect = 5e-27 Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%) Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 330 +V+ C L +L + P + +CI ++ RGL +G+YRVSG ++ ++ DR Sbjct: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578 Query: 331 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375 DG + D+ + + DI+++TGALKL+ R+LP P++ F A Sbjct: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 638 Query: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435 +S +++ L + E++ +P +++TLRYL+ HL +V + N M NLGIVFGPTL Sbjct: 639 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 698 Query: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 RP ++++ H + Y +VQ+++ N LF Sbjct: 699 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 730 >gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sapiens] Length = 547 Score = 119 bits (299), Expect = 5e-27 Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%) Query: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 330 +V+ C L +L + P + +CI ++ RGL +G+YRVSG ++ ++ DR Sbjct: 335 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 394 Query: 331 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375 DG + D+ + + DI+++TGALKL+ R+LP P++ F A Sbjct: 395 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 454 Query: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435 +S +++ L + E++ +P +++TLRYL+ HL +V + N M NLGIVFGPTL Sbjct: 455 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 514 Query: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468 RP ++++ H + Y +VQ+++ N LF Sbjct: 515 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 546 >gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] Length = 1444 Score = 118 bits (295), Expect = 1e-26 Identities = 66/206 (32%), Positives = 110/206 (53%), Gaps = 8/206 (3%) Query: 269 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 328 K + CDLT +++ P V+ C IE G+ +G+YR+SG T +I+ ++ F Sbjct: 13 KGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIV-DGIYRLSGVTSNIQRLRQEF 71 Query: 329 DRDGEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEA 387 D + D++ VY DI+ + KLYFR+LP P++TY+ Y KF +A + +L Sbjct: 72 GSD-QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLAR 130 Query: 388 VHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTL 447 + V+ LPP+HY TL YL+ HL + M+A NL +V+ P L+R E Sbjct: 131 IQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCN 190 Query: 448 HD-----MRYQKLIVQILIENEDVLF 468 D +R Q+++++ ++ + D +F Sbjct: 191 GDAAFLAVRVQQVVIEFILNHVDQIF 216 >gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] Length = 1227 Score = 117 bits (293), Expect = 2e-26 Identities = 62/167 (37%), Positives = 95/167 (56%), Gaps = 1/167 (0%) Query: 274 VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 333 V+ + + K ++ P +V C+ EIE RG++ G+YRVSG I+ +K AFD + + Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066 Query: 334 KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLM 393 + + D+N I G LKLYFR+LP P+ T + Y F + +S+ + + +L+ Sbjct: 1067 DVSVMMSEM-DVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLL 1125 Query: 394 LLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE 440 LP A+ T +L+ HLK+V E N M+ NL VFGPTL+RP E Sbjct: 1126 SLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSE 1172 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,759,383 Number of Sequences: 37866 Number of extensions: 793759 Number of successful extensions: 3081 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 189 Number of HSP's successfully gapped in prelim test: 110 Number of HSP's that attempted gapping in prelim test: 2614 Number of HSP's gapped (non-prelim): 401 length of query: 468 length of database: 18,247,518 effective HSP length: 106 effective length of query: 362 effective length of database: 14,233,722 effective search space: 5152607364 effective search space used: 5152607364 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.