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Search of human proteins with 47575849
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47575849 docking protein 6 [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47575849 docking protein 6 [Homo sapiens] 677 0.0
gi|29544726 docking protein 5 [Homo sapiens] 456 e-128
gi|20070302 docking protein 4 [Homo sapiens] 427 e-120
gi|41406050 docking protein 2 [Homo sapiens] 74 2e-13
gi|4503357 docking protein 1 [Homo sapiens] 72 9e-13
gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s... 60 4e-09
gi|110347414 fibroblast growth factor receptor substrate 2 [Homo... 55 1e-07
gi|110347408 fibroblast growth factor receptor substrate 2 [Homo... 55 1e-07
gi|221554537 docking protein 3 isoform 1 [Homo sapiens] 53 4e-07
gi|5031805 insulin receptor substrate 1 [Homo sapiens] 52 7e-07
gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] 46 5e-05
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 44 3e-04
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 35 0.12
gi|156938343 talin 2 [Homo sapiens] 34 0.21
gi|221139728 pleckstrin homology domain containing, family M (wi... 32 0.60
gi|62953127 polyhomeotic 1-like [Homo sapiens] 32 0.78
gi|39777614 SS18-like protein 1 [Homo sapiens] 30 2.3
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 30 3.9
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 30 3.9
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 30 3.9
gi|105990535 coagulation factor V precursor [Homo sapiens] 29 6.6
gi|155969707 insulin-degrading enzyme [Homo sapiens] 29 6.6
gi|214830451 sequestosome 1 isoform 2 [Homo sapiens] 29 6.6
gi|214830438 sequestosome 1 isoform 2 [Homo sapiens] 29 6.6
gi|4505571 sequestosome 1 isoform 1 [Homo sapiens] 29 6.6
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 29 6.6
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H... 29 6.6
gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H... 29 6.6
gi|187828635 NOL1/NOP2/Sun domain family, member 7 [Homo sapiens] 28 8.7
>gi|47575849 docking protein 6 [Homo sapiens]
Length = 331
Score = 677 bits (1748), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT 60
MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT
Sbjct: 1 MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT 60
Query: 61 ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS 120
ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS
Sbjct: 61 ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS 120
Query: 121 LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP 180
LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP
Sbjct: 121 LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP 180
Query: 181 LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE 240
LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE
Sbjct: 181 LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE 240
Query: 241 MEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTF 300
MEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTF
Sbjct: 241 MEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTF 300
Query: 301 PSYAPEQSEEAQQPLSRSSSYGFSYSSSLIQ 331
PSYAPEQSEEAQQPLSRSSSYGFSYSSSLIQ
Sbjct: 301 PSYAPEQSEEAQQPLSRSSSYGFSYSSSLIQ 331
>gi|29544726 docking protein 5 [Homo sapiens]
Length = 306
Score = 456 bits (1172), Expect = e-128
Identities = 216/307 (70%), Positives = 262/307 (85%), Gaps = 3/307 (0%)
Query: 1 MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT 60
MASNFNDIVKQGYV+IRSR+LGI++RCWLVFKKASSKGP+RLEKF DE+AAYFR +HKVT
Sbjct: 1 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT 60
Query: 61 ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS 120
EL+N+KN+ RLP+ TKKHA+ I F+D+TSKTFACES+LEA+EWCK L MEC+GTR+NDIS
Sbjct: 61 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS 120
Query: 121 LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP 180
LGEPDLLA GV+REQ+ERFNVYLMP+PNLD++GEC +QIT+E I LWD+ N +VKL+ WP
Sbjct: 121 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP 180
Query: 181 LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE 240
LS+LRRYGRD+TWFTFE+GRMC+TGEGLF FQTR+GE IYQKVHSA LAIAEQHERL L+
Sbjct: 181 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERL-LQ 239
Query: 241 MEQKARLQTSLTE-PMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQT 299
+ + LQ ++E +LS + LPRSAYW HITRQ+S G++Y LQ K+ R +T
Sbjct: 240 SVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVS-SPLKLHRTET 298
Query: 300 FPSYAPE 306
FP+Y E
Sbjct: 299 FPAYRSE 305
>gi|20070302 docking protein 4 [Homo sapiens]
Length = 326
Score = 427 bits (1098), Expect = e-120
Identities = 202/297 (68%), Positives = 248/297 (83%), Gaps = 2/297 (0%)
Query: 1 MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT 60
MA+NF+DIVKQGYVK++SRKLGI+RRCWLVF+K+SSKGP+RLEK+PDEK+ R KVT
Sbjct: 1 MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT 60
Query: 61 ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS 120
E+ N+K +TRLP+ETK+ AVAIIF D++++TF C+SELEAEEW K L +ECLG+RLNDIS
Sbjct: 61 EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS 120
Query: 121 LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP 180
LGEPDLLA GVQ EQ +RFNV+L+P PNLD+YGEC +QITHENIYLWDIHN +VKLV WP
Sbjct: 121 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP 180
Query: 181 LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE 240
L SLRRYGRD+T FTFE+GRMCD GEGL+TFQT+EGE IYQ+VHSATLAIAEQH+R++LE
Sbjct: 181 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE 240
Query: 241 MEQKARLQTSLTEPMT--LSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMS 295
ME+ RL TE + + + LPRSAYWHHIT ++ E S G G+G+++ S
Sbjct: 241 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGEGYGAAQAS 297
>gi|41406050 docking protein 2 [Homo sapiens]
Length = 412
Score = 73.6 bits (179), Expect = 2e-13
Identities = 71/280 (25%), Positives = 118/280 (42%), Gaps = 34/280 (12%)
Query: 9 VKQGYVKIRSRKLGIFRRCWLVFKKASSKGP----RRLE-KFPDEKAAYFRNFHKVTELH 63
VKQG++ ++ ++ F + W F + G RLE + EK KV L
Sbjct: 6 VKQGFLYLQQQQT--FGKKWRRFGASLYGGSDCALARLELQEGPEKPRRCEAARKVIRLS 63
Query: 64 NIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAE--EWCKHLCMECLGTRLNDIS- 120
+ + E F ET + + AE +W + +C+ + ++S
Sbjct: 64 DCLRVAEAGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQAICLLAFPGQRKELSG 123
Query: 121 ---------LGEPDLLAAGVQREQNERFNVYLMPTPNLD---IYGECTMQITHENIYLWD 168
+ E +L ++ V ++ F V + PT + + G T++ + LW
Sbjct: 124 PEGKQSRPCMEENELYSSAVTVGPHKEFAVTMRPTEASERCHLRGSYTLRAGESALELWG 183
Query: 169 IHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATL 228
+L WP LRR+GRD F+FE+GR C +GEG F F+TR+G I+ L
Sbjct: 184 GPEPGTQLYDWPYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEFETRQGNEIF-------L 236
Query: 229 AIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAY 268
A+ E + ++ A T +P T+ S+ P S Y
Sbjct: 237 ALEE-----AISAQKNAAPATPQPQPATIPASLPRPDSPY 271
>gi|4503357 docking protein 1 [Homo sapiens]
Length = 481
Score = 71.6 bits (174), Expect = 9e-13
Identities = 67/245 (27%), Positives = 107/245 (43%), Gaps = 28/245 (11%)
Query: 9 VKQGYVKIRSRKLGI--FRRCWLVFKKASSKGPRRLEKFPDE-------KAAYFRNFHKV 59
V +G + ++S++ G +R+ W V AS G RLE F + + + R KV
Sbjct: 5 VMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDCKV 64
Query: 60 TELHNIKNITRLPRETKKHAVAIIFHDET---SKTFACESELEAEEWCKHLCMEC----- 111
L ++ + ET A F +T S A ++ A W + LC
Sbjct: 65 IRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAA-WVQTLCRNAFPKGS 123
Query: 112 --LGTRLNDISLGEPDLLAAGVQRE--QNERFNVYLMPTPNLD---IYGECTMQITHENI 164
L N L ++L + + +F V + T + ++G +++ E +
Sbjct: 124 WTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAERL 183
Query: 165 YLWDI---HNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQ 221
L + L+ WP + LRRYGRD F+FE+GR C +G G FTFQT +G I+Q
Sbjct: 184 TLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQ 243
Query: 222 KVHSA 226
V +A
Sbjct: 244 AVETA 248
>gi|5730059 fibroblast growth factor receptor substrate 3 [Homo
sapiens]
Length = 492
Score = 59.7 bits (143), Expect = 4e-09
Identities = 29/68 (42%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query: 153 GECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQ 212
G M++T + L H + + V WP LRRYG DS F+FESGR C TG+G+F F+
Sbjct: 34 GSGVMELTQSELVL---HLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90
Query: 213 TREGEMIY 220
E I+
Sbjct: 91 CSRAEEIF 98
>gi|110347414 fibroblast growth factor receptor substrate 2 [Homo
sapiens]
Length = 508
Score = 54.7 bits (130), Expect = 1e-07
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 22/169 (13%)
Query: 153 GECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQ 212
G M++T + L+ VK W LRRYG DS F+FESGR C TG+G+F F+
Sbjct: 34 GSGIMELTDTELILYTRKRDSVK---WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90
Query: 213 TREGE----MIYQKVHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAY 268
E M+ + + + ++ + E+ + ++ QT L P T PR+
Sbjct: 91 CARAEELFNMLQEIMQNNSINVVEE------PVVERNNHQTELEVPRT-------PRTPT 137
Query: 269 WHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYA--PEQSEEAQQPL 315
QN G SS S A P EE+ PL
Sbjct: 138 TPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPL 186
>gi|110347408 fibroblast growth factor receptor substrate 2 [Homo
sapiens]
Length = 508
Score = 54.7 bits (130), Expect = 1e-07
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 22/169 (13%)
Query: 153 GECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQ 212
G M++T + L+ VK W LRRYG DS F+FESGR C TG+G+F F+
Sbjct: 34 GSGIMELTDTELILYTRKRDSVK---WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90
Query: 213 TREGE----MIYQKVHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAY 268
E M+ + + + ++ + E+ + ++ QT L P T PR+
Sbjct: 91 CARAEELFNMLQEIMQNNSINVVEE------PVVERNNHQTELEVPRT-------PRTPT 137
Query: 269 WHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYA--PEQSEEAQQPL 315
QN G SS S A P EE+ PL
Sbjct: 138 TPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPL 186
>gi|221554537 docking protein 3 isoform 1 [Homo sapiens]
Length = 496
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 12/89 (13%)
Query: 176 LVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHE 235
L WP LR++G D F+FE+GR C +GEGLF F T + + V AIA Q E
Sbjct: 256 LYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDLCRAVAG---AIARQRE 312
Query: 236 RLMLEMEQKARLQTSLTEPMTLSKSISLP 264
RL + + +P L ++ SLP
Sbjct: 313 RLP---------ELTRPQPCPLPRATSLP 332
>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
Length = 1242
Score = 52.0 bits (123), Expect = 7e-07
Identities = 74/306 (24%), Positives = 117/306 (38%), Gaps = 58/306 (18%)
Query: 2 ASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNF--HKV 59
+ F+D+ K GY++ + + +R +++ + + GP RLE + +EK ++ +
Sbjct: 7 SDGFSDVRKVGYLR---KPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRS 63
Query: 60 TELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCM---------- 109
L + NI + KH VA+ DE A +SE E + W + L
Sbjct: 64 IPLESCFNINKRADSKNKHLVALYTRDEHF-AIAADSEAEQDSWYQALLQLHNRAKGHHD 122
Query: 110 ------------EC-----LGTRLNDISLGEPDLLAAGVQREQNERFNVYLMP-----TP 147
C LG D+S G+ A E + V L P T
Sbjct: 123 GAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAF-----KEVWQVILKPKGLGQTK 177
Query: 148 NL-DIYGECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGE 206
NL IY C T + L N++ V+ L ++RR G +F E GR TG
Sbjct: 178 NLIGIYRLCLTSKTISFVKL----NSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGP 233
Query: 207 GLFTFQTREGEMIYQKVHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRS 266
G F Q + ++ Q +H L M M + R ++ S IS+P
Sbjct: 234 GEFWMQV-DDSVVAQNMHETIL-------EAMRAMSDEFRPRSKSQSSSNCSNPISVPLR 285
Query: 267 AYWHHI 272
HH+
Sbjct: 286 R--HHL 289
>gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]
Length = 504
Score = 45.8 bits (107), Expect = 5e-05
Identities = 58/214 (27%), Positives = 88/214 (41%), Gaps = 34/214 (15%)
Query: 11 QGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVTELHNIKNITR 70
+G VK+R K ++ WLV +K S L +K+ + + + L +++I
Sbjct: 8 EGQVKLRDGKK--WKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSL-TLEDICG 64
Query: 71 L----PRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDISLGEPDL 126
L P E H +AI+ C S+ + H M R+ +LGE
Sbjct: 65 LEPGLPYEGLVHTLAIV----------CLSQAIMLGFDSHEAMCAWDARIR-YALGEV-- 111
Query: 127 LAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLW-DIHNAKVKLVMWPLSSLR 185
RF+V + P L+ G T+ + ++ + L DI A W LS LR
Sbjct: 112 ----------HRFHVTVAPGTKLES-GPATLHLCNDVLVLARDIPPAVTG--QWKLSDLR 158
Query: 186 RYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMI 219
RYG + F FE G C G+F + EGE I
Sbjct: 159 RYGAVPSGFIFEGGTRCGYWAGVFFLSSAEGEQI 192
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 43.5 bits (101), Expect = 3e-04
Identities = 66/278 (23%), Positives = 110/278 (39%), Gaps = 48/278 (17%)
Query: 7 DIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNF---------- 56
++ K+GY +R +K G R + V K ++ P RLE + E A FR+
Sbjct: 78 EVCKRGY--LRKQKHG--HRRYFVLKLETADAPARLEYY--ENARKFRHSVRAAAAAAAA 131
Query: 57 -------------HKVTELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEW 103
+V L+ ++++ +H +A+ DE A E+E E E W
Sbjct: 132 AASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVA-ENESEQESW 190
Query: 104 ---CKHLCMECLGTRLNDISL---GEPDLLAAGVQREQ---NERFNVYLMPTP---NLDI 151
L +E R + GEP LAA E + + V + P ++
Sbjct: 191 YLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKEL 250
Query: 152 YGECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTF 211
G + +T E + + N +V V+ L S+RR G +F E GR G G
Sbjct: 251 SGVFRLCLTDEEVVFVRL-NTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWM 309
Query: 212 QTREGEMIYQKVHSATLAIAEQHERLMLEMEQKARLQT 249
Q + ++ Q +H L + R + E +AR ++
Sbjct: 310 QV-DDCVVAQNMHELFL----EKMRALCADEYRARCRS 342
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 34.7 bits (78), Expect = 0.12
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 171 NAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAI 230
N + V L ++RR G ++F E GR TG G Q + ++ Q +H T+
Sbjct: 232 NCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQA-DDSVVAQNIHE-TILE 289
Query: 231 AEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAYWHHI 272
A + + + E +++ Q+S + + IS+P + HH+
Sbjct: 290 AMKALKELFEFRPRSKSQSS---GSSATHPISVPGARRHHHL 328
>gi|156938343 talin 2 [Homo sapiens]
Length = 2542
Score = 33.9 bits (76), Expect = 0.21
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 10/108 (9%)
Query: 159 ITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEM 218
IT +++ D K L WPL++++R+ FT + G + E ++ QT EGE
Sbjct: 335 ITKDSVMRVD-EKTKEVLQEWPLTTVKRWAASPKSFTLDFG---EYQESYYSVQTTEGEQ 390
Query: 219 IYQKVH---SATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISL 263
I Q + L + +R LE ++++ T L E ++ KS L
Sbjct: 391 ISQLIAGYIDIILKKKQSKDRFGLEGDEES---TMLEESVSPKKSTIL 435
>gi|221139728 pleckstrin homology domain containing, family M (with
RUN domain) member 2 [Homo sapiens]
Length = 1019
Score = 32.3 bits (72), Expect = 0.60
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 76 KKHAVAIIFHDETSKTFACESELEAEEWCKHLC 108
+ HA +I D + ESE E EW +HLC
Sbjct: 837 RPHAFQVILSDRPCLELSAESEAEMAEWMQHLC 869
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 32.0 bits (71), Expect = 0.78
Identities = 21/73 (28%), Positives = 34/73 (46%)
Query: 242 EQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFP 301
+ + + QT + +PM S +SLP A S + ++ G++KMS AQ P
Sbjct: 463 QSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPP 522
Query: 302 SYAPEQSEEAQQP 314
+ P Q +QP
Sbjct: 523 PHIPVQVVGTRQP 535
>gi|39777614 SS18-like protein 1 [Homo sapiens]
Length = 396
Score = 30.4 bits (67), Expect = 2.3
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)
Query: 271 HITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGFSYSSS 328
H Q+S+ ++ G G S M + Y P Q +QQ L + YG YS S
Sbjct: 207 HYQGQSSI----AMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHS 260
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 29.6 bits (65), Expect = 3.9
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Query: 246 RLQ-TSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYS 283
RLQ T L EP L +S +P+ ++W T QNS G YS
Sbjct: 328 RLQLTELQEPAELVESDGVPKPSFWP--TAQNSGGSAYS 364
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 29.6 bits (65), Expect = 3.9
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Query: 246 RLQ-TSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYS 283
RLQ T L EP L +S +P+ ++W T QNS G YS
Sbjct: 328 RLQLTELQEPAELVESDGVPKPSFWP--TAQNSGGSAYS 364
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 29.6 bits (65), Expect = 3.9
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Query: 246 RLQ-TSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYS 283
RLQ T L EP L +S +P+ ++W T QNS G YS
Sbjct: 328 RLQLTELQEPAELVESDGVPKPSFWP--TAQNSGGSAYS 364
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 28.9 bits (63), Expect = 6.6
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 275 QNSVGEIYSLQGHGFGSSKMSRAQTFPSYAPE--QSEEAQQPLSRSSSYGFSYSSS 328
+N YSL HG K S +T+ +PE + + A QP +SSY + + ++
Sbjct: 1661 KNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQP---NSSYTYVWHAT 1713
>gi|155969707 insulin-degrading enzyme [Homo sapiens]
Length = 1019
Score = 28.9 bits (63), Expect = 6.6
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 10/146 (6%)
Query: 131 VQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRD 190
V +++NE N ++IY + MQ T EN++L +++ P + R
Sbjct: 778 VYQQRNEVHN-----NCGIEIYYQTDMQSTSENMFL----ELFCQIISEPCFNTLRTKEQ 828
Query: 191 STWFTFESGRMCDTGEGL-FTFQTREGEMIYQKVHSATLAIAEQHERLMLEMEQKARLQT 249
+ F R + +GL F Q+ + + A L E+ M E + +Q
Sbjct: 829 LGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQA 888
Query: 250 SLTEPMTLSKSISLPRSAYWHHITRQ 275
+ K +S + YW I Q
Sbjct: 889 LAIRRLDKPKKLSAECAKYWGEIISQ 914
>gi|214830451 sequestosome 1 isoform 2 [Homo sapiens]
Length = 356
Score = 28.9 bits (63), Expect = 6.6
Identities = 29/116 (25%), Positives = 44/116 (37%), Gaps = 22/116 (18%)
Query: 223 VHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQN---SVG 279
V AT ++AEQ ++ LE E + Q + W H++ + S G
Sbjct: 216 VEGATQSLAEQMRKIALESEGRPEEQ--------MESDNCSGGDDDWTHLSSKEVDPSTG 267
Query: 280 EIYSLQ-----------GHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGFS 324
E+ SLQ G + + A +P PE + LS+ S GFS
Sbjct: 268 ELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFS 323
>gi|214830438 sequestosome 1 isoform 2 [Homo sapiens]
Length = 356
Score = 28.9 bits (63), Expect = 6.6
Identities = 29/116 (25%), Positives = 44/116 (37%), Gaps = 22/116 (18%)
Query: 223 VHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQN---SVG 279
V AT ++AEQ ++ LE E + Q + W H++ + S G
Sbjct: 216 VEGATQSLAEQMRKIALESEGRPEEQ--------MESDNCSGGDDDWTHLSSKEVDPSTG 267
Query: 280 EIYSLQ-----------GHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGFS 324
E+ SLQ G + + A +P PE + LS+ S GFS
Sbjct: 268 ELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFS 323
>gi|4505571 sequestosome 1 isoform 1 [Homo sapiens]
Length = 440
Score = 28.9 bits (63), Expect = 6.6
Identities = 29/116 (25%), Positives = 44/116 (37%), Gaps = 22/116 (18%)
Query: 223 VHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQN---SVG 279
V AT ++AEQ ++ LE E + Q + W H++ + S G
Sbjct: 300 VEGATQSLAEQMRKIALESEGRPEEQ--------MESDNCSGGDDDWTHLSSKEVDPSTG 351
Query: 280 EIYSLQ-----------GHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGFS 324
E+ SLQ G + + A +P PE + LS+ S GFS
Sbjct: 352 ELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFS 407
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 28.9 bits (63), Expect = 6.6
Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 244 KARLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKM-SRAQTFPS 302
K +L S++ + + SA + +R +S YS G GSS+ SR+ ++ S
Sbjct: 526 KKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYS----GSGSSRSRSRSSSYSS 581
Query: 303 YAPEQSEEAQQPLSRSSSYGFSYSSS 328
Y+ S + SRS S FS S S
Sbjct: 582 YSSRSSRHSSFSGSRSRSRSFSSSPS 607
>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
sapiens]
Length = 358
Score = 28.9 bits (63), Expect = 6.6
Identities = 23/103 (22%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
Query: 2 ASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVTE 61
A ++++KQGY++ +S+ F W S+G + +EK+ + + +
Sbjct: 102 AQELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRG--LFYYYANEKSKQPKGTFLI-K 158
Query: 62 LHNIKNITRLPRETKKHA-VAIIFHDETSKTFACESELEAEEW 103
+ ++ L R++KK + + D S F S EA +W
Sbjct: 159 GYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDW 201
>gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo
sapiens]
Length = 359
Score = 28.9 bits (63), Expect = 6.6
Identities = 23/103 (22%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
Query: 2 ASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVTE 61
A ++++KQGY++ +S+ F W S+G + +EK+ + + +
Sbjct: 102 AQELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRG--LFYYYANEKSKQPKGTFLI-K 158
Query: 62 LHNIKNITRLPRETKKHA-VAIIFHDETSKTFACESELEAEEW 103
+ ++ L R++KK + + D S F S EA +W
Sbjct: 159 GYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDW 201
>gi|187828635 NOL1/NOP2/Sun domain family, member 7 [Homo sapiens]
Length = 718
Score = 28.5 bits (62), Expect = 8.7
Identities = 23/116 (19%), Positives = 55/116 (47%), Gaps = 20/116 (17%)
Query: 5 FNDIVKQGYVKIRS------RKLGIFRRCW--LVFKKASSKGPRRLEKFPDEKAAYFRNF 56
+N++ ++GY K++S + + + C+ L+F ++ F D K F++
Sbjct: 219 YNNLKRRGYNKVKSVLHIDDKVFAVDQHCYDVLIFPSHLKNDLINIDLFKDYKLI-FQDK 277
Query: 57 HKVTELHNIKNITRLPRE----------TKKHAVAIIFHDETSKTFACESELEAEE 102
+ +H++K + + + T H ++I+ ++ TSK F C + +A++
Sbjct: 278 SRSLAVHSVKALLNMDDDVLMVNTGSWYTVSH-MSILTNNNTSKVFVCGVQSQAKD 332
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,861,379
Number of Sequences: 37866
Number of extensions: 497426
Number of successful extensions: 1327
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1308
Number of HSP's gapped (non-prelim): 31
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.