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Search of human proteins with 47132553
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo
sapiens]
(2296 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 4792 0.0
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 4100 0.0
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 3936 0.0
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 3522 0.0
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 2990 0.0
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 2990 0.0
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens] 1440 0.0
gi|153946395 tenascin C precursor [Homo sapiens] 358 3e-98
gi|157384973 tenascin R [Homo sapiens] 356 2e-97
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 342 2e-93
gi|62988324 tenascin N [Homo sapiens] 300 1e-80
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 283 2e-75
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 281 4e-75
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 224 6e-58
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 201 9e-51
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 159 3e-38
gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 152 5e-36
gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 152 5e-36
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 152 5e-36
gi|222352127 sidekick 2 [Homo sapiens] 148 7e-35
gi|110349719 titin isoform N2-A [Homo sapiens] 148 7e-35
gi|110349717 titin isoform novex-2 [Homo sapiens] 148 7e-35
gi|110349713 titin isoform novex-1 [Homo sapiens] 148 7e-35
gi|110349715 titin isoform N2-B [Homo sapiens] 148 7e-35
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 147 1e-34
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 146 3e-34
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 146 3e-34
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 144 8e-34
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 142 3e-33
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 142 3e-33
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 4792 bits (12429), Expect = 0.0
Identities = 2296/2296 (100%), Positives = 2296/2296 (100%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI
Sbjct: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
Query: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA
Sbjct: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
Query: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860
RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR
Sbjct: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860
Query: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 1920
PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI
Sbjct: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 1920
Query: 1921 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1980
LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR
Sbjct: 1921 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1980
Query: 1981 HRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTS 2040
HRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTS
Sbjct: 1981 HRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTS 2040
Query: 2041 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 2100
EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV
Sbjct: 2041 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 2100
Query: 2101 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2160
GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW
Sbjct: 2101 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2160
Query: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2220
CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK
Sbjct: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2220
Query: 2221 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2280
EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE
Sbjct: 2221 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2280
Query: 2281 CFMPLDVQADREDSRE 2296
CFMPLDVQADREDSRE
Sbjct: 2281 CFMPLDVQADREDSRE 2296
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 4100 bits (10632), Expect = 0.0
Identities = 2013/2341 (85%), Positives = 2076/2341 (88%), Gaps = 56/2341 (2%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
SQPLVQTAVT I P L FT V S+ W P Q++ YRV + E + E+
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678
Query: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
APD + + GL ++Y VSV AL D + S+P G +T + P + T T T
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
Query: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
+++ W +TG++V P P++ + PD S ++GL T Y++ +Y L
Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
Query: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855
D S P V+ + P R T ++ +SW+ ITG+ + P +
Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-----DELPQLVTL 1910
+ +P V TITGL+PGT+Y IY+ L +N +S P++ T L L T
Sbjct: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 1915
Query: 1911 PH----------------------PNLHGPEIL--DVPSTVQKTPFVTHPGYD-TGNGIQ 1945
P+ P E++ P + T PG + T I
Sbjct: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
Query: 1946 LPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGH--IPRED 2003
L +P +G++ ++ F T I+ P G++ +G I E
Sbjct: 1976 LKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQ-----LPGTSGQQPSVGQQMIFEEH 2030
Query: 2004 VDYHLYP--------HGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP 2055
P H P P + GQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP
Sbjct: 2031 GFRRTTPPTTATPIRHRPRPYP-PNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP 2089
Query: 2056 LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDS 2115
LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDS
Sbjct: 2090 LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDS 2149
Query: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWD 2175
CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWD
Sbjct: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWD 2209
Query: 2176 RQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQ 2235
RQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQ
Sbjct: 2210 RQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQ 2269
Query: 2236 RGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSR 2295
RGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSR
Sbjct: 2270 RGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSR 2329
Query: 2296 E 2296
E
Sbjct: 2330 E 2330
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 3936 bits (10207), Expect = 0.0
Identities = 1901/1903 (99%), Positives = 1902/1903 (99%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI
Sbjct: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
Query: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA
Sbjct: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
Query: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860
RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR
Sbjct: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860
Query: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 1903
PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT +
Sbjct: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQ 1903
Score = 1071 bits (2769), Expect = 0.0
Identities = 634/1584 (40%), Positives = 864/1584 (54%), Gaps = 121/1584 (7%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
Query: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
Query: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
Query: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V P +
Sbjct: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949
Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
+ +S+ + L P Y + A+ +ES T TT + + E
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008
Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY ++
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAVPPP 1270
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ + PP
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177
Query: 1271 TDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTN 1327
T+L PDT + V+W + D+T + + +P ++ + E + ++ N
Sbjct: 1178 TNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
Query: 1328 LLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT-IT 1386
L PG EY VSV +V + ES P+ + PT + F++I ++ V W P + +T
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST 1446
+ +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES L G+Q T
Sbjct: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
Query: 1447 VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
D P ++ T S + W AP T+ YRI + + +E VP S+++ T++
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSS 1566
L PG +Y +++ A+ GR +SP S T D P ++V S+ + W +
Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES----Q 1622
V YR+T G P + T ++ TI GL+P V+Y ++VYA G+S +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
Query: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
P+ T I P+ ++ T V S+S +W P + +TGYRV TPK GP K P
Sbjct: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
Query: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1742
D + + + GL +Y VSVYA + S+P V T + + P + T T T+++
Sbjct: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTTIPAPTDLKFTQVTPTSLSA 1650
Query: 1743 SWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
W +TG++V P P++ + PD S ++GL T Y++ +Y L D
Sbjct: 1651 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1710
Query: 1802 SSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 1859
S P V+ + P R T ++ +SW+ ITG+ + P + +
Sbjct: 1711 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQR 1769
Query: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 1919
+P V TITGL+PGT+Y IY+ L +N +S P++ +
Sbjct: 1770 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV------------------IDAST 1811
Query: 1920 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 1979
+D PS ++ F+ T N + + + G + +E+ G +PP P
Sbjct: 1812 AIDAPSNLR---FLA----TTPNSLLVSWQPPRARITGYIIKYEKPG----SPPREVVP- 1859
Query: 1980 RHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAS-------TGQEALSQTTIS 2032
RPRP V E G P +Y +Y N + TGQEALSQTTIS
Sbjct: 1860 --RPRP---GVTEATITGLEP--GTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTIS 1912
Query: 2033 WAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHK 2092
WAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHK
Sbjct: 1913 WAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHK 1972
Query: 2093 VREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGH 2152
VREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGH
Sbjct: 1973 VREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGH 2032
Query: 2153 FRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTY 2212
FRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTY
Sbjct: 2033 FRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTY 2092
Query: 2213 HVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTN 2272
HVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTN
Sbjct: 2093 HVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTN 2152
Query: 2273 TNVNCPIECFMPLDVQADREDSRE 2296
TNVNCPIECFMPLDVQADREDSRE
Sbjct: 2153 TNVNCPIECFMPLDVQADREDSRE 2176
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2229 CTCFGGQRG 2237
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2109 CTCFGGQRG 2117
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2238 WRC 2240
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
Query: 597 WHC 599
W C
Sbjct: 2118 WRC 2120
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2238 WRCD 2241
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
Query: 268 WKCE 271
W+C+
Sbjct: 2118 WRCD 2121
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2216 EQWQKEYLGAICSCTCFGGQRG 2237
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2265 QR 2266
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
Query: 106 YR 107
R
Sbjct: 2145 QR 2146
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
Score = 39.3 bits (90), Expect = 0.045
Identities = 39/173 (22%), Positives = 68/173 (39%), Gaps = 31/173 (17%)
Query: 623 PNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLI 682
PNS + W P+ + I+ YI+++ S R + TI GL+PG Y +I
Sbjct: 1826 PNSLLVSWQPPR-ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1884
Query: 683 SIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS 742
+++ S P+ TG+ E++++ T +SW
Sbjct: 1885 ALKN-------------NQKSEPLIGRKKTGQ-----------EALSQTT-----ISWAP 1915
Query: 743 ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
DT S + + +EP +P T+TS + L G Y + V + +
Sbjct: 1916 FQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 1967
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 3522 bits (9132), Expect = 0.0
Identities = 1710/1901 (89%), Positives = 1757/1901 (92%), Gaps = 10/1901 (0%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
SQPLVQTAVT I P L FT V S+ W P Q++ YRV + E + E+
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678
Query: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
APD + + GL ++Y VSV AL D + S+P G +T + P + T T T
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
Query: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
+++ W +TG++V P P++ + PD S ++GL T Y++ +Y L
Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
Query: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855
D S P V+ + P R T ++ +SW+ ITG+ + P +
Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
+ +P V TITGL+PGT+Y IY+ L +N +S P++
Sbjct: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896
Score = 1696 bits (4393), Expect = 0.0
Identities = 923/1668 (55%), Positives = 1102/1668 (66%), Gaps = 110/1668 (6%)
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
Query: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
Query: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
Query: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V G
Sbjct: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035
Query: 952 QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
+ P N V+ L P Y + A+ +ES T TT + +
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095
Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
E T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151
Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
++ ++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208
Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAV 1267
Query: 1175 SPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
PPT+L PDT + V+W + D+T + + +P ++ + E + ++
Sbjct: 1268 PPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVV 1324
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
NL PG EY VSV +V + ES P+ + PT + F++I ++ V W P +
Sbjct: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT 1384
Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
+T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES L G+
Sbjct: 1385 -ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
Query: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
Q T D P ++ T S + W AP T+ YRI + + +E VP S+++
Sbjct: 1444 QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
Query: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWD 1469
T++ L PG +Y +++ A+ GR +SP S T D P ++V S+ + W
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1563
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
+ V YR+T G P + T ++ TI GL+P V+Y ++VYA G+S
Sbjct: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES-- 1621
Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGPTKTK 1588
+P+ T ID+P + TDV +SI + W V+ YRVT ++P++G
Sbjct: 1622 --QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1679
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSL 1648
G + T ++GL+P EY VSV A + ESQPL+ T T IPAPTDLKFTQVTPTSL
Sbjct: 1680 PDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSL 1738
Query: 1649 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT
Sbjct: 1739 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1798
Query: 1709 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ
Sbjct: 1799 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1858
Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS
Sbjct: 1859 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1918
Query: 1829 LLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
LLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN
Sbjct: 1919 LLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
Query: 1889 NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 1948
NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG
Sbjct: 1979 NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
Query: 1949 TSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHL 2008
TSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG
Sbjct: 2039 TSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG----------------- 2081
Query: 2009 YPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSAT 2068
QEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSAT
Sbjct: 2082 --------------QEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSAT 2127
Query: 2069 LTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVG 2128
LTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVG
Sbjct: 2128 LTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVG 2187
Query: 2129 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTC 2188
DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTC
Sbjct: 2188 DEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTC 2247
Query: 2189 LGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGG 2248
LGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGG
Sbjct: 2248 LGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGG 2307
Query: 2249 EPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2296
EPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2308 EPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2355
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2229 CTCFGGQRG 2237
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2288 CTCFGGQRG 2296
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2238 WRC 2240
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296
Query: 597 WHC 599
W C
Sbjct: 2297 WRC 2299
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2238 WRCD 2241
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296
Query: 268 WKCE 271
W+C+
Sbjct: 2297 WRCD 2300
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2216 EQWQKEYLGAICSCTCFGGQRG 2237
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2275 EQWQKEYLGAICSCTCFGGQRG 2296
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2265 QR 2266
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323
Query: 106 YR 107
R
Sbjct: 2324 QR 2325
Score = 55.5 bits (132), Expect = 6e-07
Identities = 82/340 (24%), Positives = 131/340 (38%), Gaps = 54/340 (15%)
Query: 656 EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
+ TI + SYTI GL+PG Y+ L ++ D ST+ SN T
Sbjct: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLRFLAT 1914
Query: 716 TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---A 772
TP +S +VSW ++G+ ++YE + G P+ + +P
Sbjct: 1915 TP----------------NSLLVSWQPPRARITGYIIKYE--KPGSPPREV-VPRPRPGV 1955
Query: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
T I L PG +Y + V + + + ++ +T D+ +V +
Sbjct: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT--------------DELPQLV--T 1999
Query: 833 RPQAPITGYRIVYSPSVEGSSTELNLP--ETANSVTL---SDLQPGVQYNITIYAVEENQ 887
P + G I+ PS + + P +T N + L S QP V + I+ +
Sbjct: 2000 LPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM-IFEEHGFR 2058
Query: 888 ESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
+TP TT TP P P + + TI W P + + Y + PV
Sbjct: 2059 RTTP-----PTTATPIRHR-PRPYPPNVGQEALSQTTISWAPFQD-TSEYIISCHPVGTD 2111
Query: 948 GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK 987
E Q +T A +TGL+ G TY V A+ + K
Sbjct: 2112 EEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHK 2151
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 2990 bits (7751), Expect = 0.0
Identities = 1509/2120 (71%), Positives = 1652/2120 (77%), Gaps = 78/2120 (3%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
Query: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
+ S+P+ T I P+ ++ T V S+S +W P + +TGYRV TPK GP
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676
Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
K PD + + + GL +Y VSVYA + S+P V T + N+ P+ TD
Sbjct: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734
Query: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
+I I+W + ++ ++V + P +G + + + + GL+PG++Y + +
Sbjct: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
Query: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851
L+D+ S P++ STAI AP++L+F TP SL W PP ++TGY ++ EK G
Sbjct: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
Query: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLP 1911
P +E+ P + ++GL T+Y + V ALK+ S P G T E
Sbjct: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-------- 1903
Query: 1912 HPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRT 1970
N+ P V + T ++ +T G Q+ P+ GQ
Sbjct: 1904 --NVSPPRRARVTDATETTITISWRTKTETITGFQVDAV----PANGQ------------ 1945
Query: 1971 TPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTT 2030
TPI+ R P+V G P D +LY LN NA + + +T
Sbjct: 1946 ------TPIQ---RTIKPDVRSYTITGLQPGTDYKIYLYT----LNDNARSSPVVIDAST 1992
Query: 2031 -------------------ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2070
+SW P + + YII G+ + R T AT+T
Sbjct: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
Query: 2071 GLTRGATYNIIVEALKDQQR 2090
GL G Y I V ALK+ Q+
Sbjct: 2053 GLEPGTEYTIYVIALKNNQK 2072
Score = 1788 bits (4630), Expect = 0.0
Identities = 971/1688 (57%), Positives = 1153/1688 (68%), Gaps = 58/1688 (3%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
++W+ PQ + I+ Y + + P G E +P NS T+ L+PGV Y + ++++
Sbjct: 829 VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
+QE T +T TP + + F E+T + W V
Sbjct: 886 -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
Query: 748 SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
+G+RV+ ++ G+ Q L + S T + L PG Y V+ +S G +S L+
Sbjct: 935 TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
Query: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
QTT DAP + D++++VRW+ P+A ITGYR+ + G + N+ + +
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L +LQP +Y +++ A++ NQES P TT P S P EVT+ + I
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985
WTP G+++ V P G R S + V+GL+PGV Y + + + G+E
Sbjct: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
Query: 986 SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039
P+ + T L PTNL D+ VL V W T P ITGYR+T T ++G
Sbjct: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT 1099
+ V S NL P EY VS+ +K ++ES + P + + ++T
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF-VDIT 1279
Query: 1100 ETTIVITWTP---APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
+++I + WTP + IG+++ V + G E V S G V+GL PG++Y ++
Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
L +G E AP T + PPT+L PDT + V+W + D+T + + +P
Sbjct: 1340 TLINGGE-SAPTTLTQQTAVPPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPV 1396
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
++ + E + ++ NL PG EY VSV +V + ES P+ + PT +
Sbjct: 1397 KNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1455
Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
F++I ++ V W P + +T + +R+ P E + S N++ LTNL PGTE
Sbjct: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
Query: 1334 YVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH 1393
YVVS+ ++ + ES L G+Q T D P ++ T S + W AP T+ YRI +
Sbjct: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSD 1449
+ +E VP S+++ T++ L PG +Y +++ A+ GR +SP S T D
Sbjct: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
P ++V S+ + W + V YR+T G P + T ++ TI GL+
Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
P V+Y ++VYA G+S +P+ T ID+P + TDV +SI + W V
Sbjct: 1695 PTVEYVVSVYAQNPSGES----QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
Query: 1570 TGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
+ YRVT ++P++G G + T ++GL+P EY VSV A + ESQPL+ T
Sbjct: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
T IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV
Sbjct: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
Query: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748
VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT
Sbjct: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
Query: 1749 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808
ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID
Sbjct: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868
ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA
Sbjct: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
Query: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 1928
TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ
Sbjct: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 2109
Query: 1929 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 1988
KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP
Sbjct: 2110 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 2169
Query: 1989 NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP 2048
NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP
Sbjct: 2170 NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP 2229
Query: 2049 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2108
VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL
Sbjct: 2230 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2289
Query: 2109 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2168
NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY
Sbjct: 2290 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2349
Query: 2169 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2228
KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS
Sbjct: 2350 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2409
Query: 2229 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2288
CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ
Sbjct: 2410 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2469
Query: 2289 ADREDSRE 2296
ADREDSRE
Sbjct: 2470 ADREDSRE 2477
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2229 CTCFGGQRG 2237
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2410 CTCFGGQRG 2418
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2238 WRC 2240
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418
Query: 597 WHC 599
W C
Sbjct: 2419 WRC 2421
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2238 WRCD 2241
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418
Query: 268 WKCE 271
W+C+
Sbjct: 2419 WRCD 2422
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2216 EQWQKEYLGAICSCTCFGGQRG 2237
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2397 EQWQKEYLGAICSCTCFGGQRG 2418
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2265 QR 2266
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445
Query: 106 YR 107
R
Sbjct: 2446 QR 2447
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 2990 bits (7751), Expect = 0.0
Identities = 1509/2120 (71%), Positives = 1652/2120 (77%), Gaps = 78/2120 (3%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
Query: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
+ S+P+ T I P+ ++ T V S+S +W P + +TGYRV TPK GP
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676
Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
K PD + + + GL +Y VSVYA + S+P V T + N+ P+ TD
Sbjct: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734
Query: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
+I I+W + ++ ++V + P +G + + + + GL+PG++Y + +
Sbjct: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
Query: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851
L+D+ S P++ STAI AP++L+F TP SL W PP ++TGY ++ EK G
Sbjct: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
Query: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLP 1911
P +E+ P + ++GL T+Y + V ALK+ S P G T E
Sbjct: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-------- 1903
Query: 1912 HPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRT 1970
N+ P V + T ++ +T G Q+ P+ GQ
Sbjct: 1904 --NVSPPRRARVTDATETTITISWRTKTETITGFQVDAV----PANGQ------------ 1945
Query: 1971 TPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTT 2030
TPI+ R P+V G P D +LY LN NA + + +T
Sbjct: 1946 ------TPIQ---RTIKPDVRSYTITGLQPGTDYKIYLYT----LNDNARSSPVVIDAST 1992
Query: 2031 -------------------ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2070
+SW P + + YII G+ + R T AT+T
Sbjct: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
Query: 2071 GLTRGATYNIIVEALKDQQR 2090
GL G Y I V ALK+ Q+
Sbjct: 2053 GLEPGTEYTIYVIALKNNQK 2072
Score = 1637 bits (4240), Expect = 0.0
Identities = 915/1688 (54%), Positives = 1097/1688 (64%), Gaps = 114/1688 (6%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
++W+ PQ + I+ Y + + P G E +P NS T+ L+PGV Y + ++++
Sbjct: 829 VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
+QE T +T TP + + F E+T + W V
Sbjct: 886 -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
Query: 748 SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
+G+RV+ ++ G+ Q L + S T + L PG Y V+ +S G +S L+
Sbjct: 935 TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
Query: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
QTT DAP + D++++VRW+ P+A ITGYR+ + G + N+ + +
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L +LQP +Y +++ A++ NQES P TT P S P EVT+ + I
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985
WTP G+++ V P G R S + V+GL+PGV Y + + + G+E
Sbjct: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
Query: 986 SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039
P+ + T L PTNL D+ VL V W T P ITGYR+T T ++G
Sbjct: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT 1099
+ V S NL P EY VS+ +K ++ES + P + + ++T
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF-VDIT 1279
Query: 1100 ETTIVITWTP---APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
+++I + WTP + IG+++ V + G E V S G V+GL PG++Y ++
Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
L +G E AP T + PPT+L PDT + V+W + D+T + + +P
Sbjct: 1340 TLINGGE-SAPTTLTQQTAVPPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPV 1396
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
++ + E + ++ NL PG EY VSV +V + ES P+ + PT +
Sbjct: 1397 KNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1455
Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
F++I ++ V W P + +T + +R+ P E + S N++ LTNL PGTE
Sbjct: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
Query: 1334 YVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH 1393
YVVS+ ++ + ES L G+Q T D P ++ T S + W AP T+ YRI +
Sbjct: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSD 1449
+ +E VP S+++ T++ L PG +Y +++ A+ GR +SP S T D
Sbjct: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
P ++V S+ + W + V YR+T G P + T ++ TI GL+
Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
P V+Y ++VYA G+S +P+ T ID+P + TDV +SI + W V
Sbjct: 1695 PTVEYVVSVYAQNPSGES----QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
Query: 1570 TGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
+ YRVT ++P++G G + T ++GL+P EY VSV A + ESQPL+ T
Sbjct: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
T IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV
Sbjct: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
Query: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748
VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT
Sbjct: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
Query: 1749 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808
ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID
Sbjct: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868
ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA
Sbjct: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
Query: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 1928
TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT VQ
Sbjct: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-------------------------VQ 2084
Query: 1929 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 1988
KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP
Sbjct: 2085 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 2144
Query: 1989 NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP 2048
NVG QEALSQTTISWAPFQDTSEYIISCHP
Sbjct: 2145 NVG-------------------------------QEALSQTTISWAPFQDTSEYIISCHP 2173
Query: 2049 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2108
VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL
Sbjct: 2174 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2233
Query: 2109 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2168
NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY
Sbjct: 2234 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2293
Query: 2169 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2228
KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS
Sbjct: 2294 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2353
Query: 2229 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2288
CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ
Sbjct: 2354 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2413
Query: 2289 ADREDSRE 2296
ADREDSRE
Sbjct: 2414 ADREDSRE 2421
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2229 CTCFGGQRG 2237
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2354 CTCFGGQRG 2362
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2238 WRC 2240
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362
Query: 597 WHC 599
W C
Sbjct: 2363 WRC 2365
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2238 WRCD 2241
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362
Query: 268 WKCE 271
W+C+
Sbjct: 2363 WRCD 2366
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2216 EQWQKEYLGAICSCTCFGGQRG 2237
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2341 EQWQKEYLGAICSCTCFGGQRG 2362
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2265 QR 2266
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389
Query: 106 YR 107
R
Sbjct: 2390 QR 2391
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317
>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
Length = 657
Score = 1440 bits (3728), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
Score = 115 bits (287), Expect = 6e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2229 CTCFGGQRG 2237
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 98.6 bits (244), Expect = 6e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2238 WRC 2240
W C
Sbjct: 597 WHC 599
Score = 88.2 bits (217), Expect = 8e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2238 WRCD 2241
W+C+
Sbjct: 268 WKCE 271
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2216 EQWQKEYLGAICSCTCFGGQRG 2237
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 62.0 bits (149), Expect = 6e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2265 QR 2266
R
Sbjct: 106 YR 107
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 358 bits (920), Expect = 3e-98
Identities = 321/1314 (24%), Positives = 549/1314 (41%), Gaps = 71/1314 (5%)
Query: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
Query: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
Query: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
Query: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
Query: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
Query: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
Query: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
+ P+S + + VP +L T + D +R+ W P F ++ E+
Sbjct: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301
Query: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
L++ S ++ + L GT Y V++ H + PL T L + S++ +
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
++W A + I+ + + +P S ++ + L T Y VSI +
Sbjct: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421
Query: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+P+L + ST + +L V TP S +SW A + I ++
Sbjct: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481
Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
E+ + G++ TA ISGL P D+ + + G +P+ +K IS TE + +
Sbjct: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536
Query: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
++D+ +V W+ S + + VT + T Q ++ + GL + Y
Sbjct: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596
Query: 1610 VSVYAQNPSGESQPLVQTAVTTI-PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668
V V +++PL VT P +L + TP WT + +++
Sbjct: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656
Query: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR 1728
+K EI L + ++GL AT+YE+ +Y + S+ + TT + P+
Sbjct: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPK 1714
Query: 1729 RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
+D TE + T+SWR T + F++ VP G TP T+ + L PG +
Sbjct: 1715 EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVE 1774
Query: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
Y + + + S PV +TA+D PS L T + L WQP A + Y+I Y
Sbjct: 1775 YLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY- 1833
Query: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1902
G E+ E +T LEP TEYT+ + A K QKS + + TD
Sbjct: 1834 -TGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTD 1886
Score = 308 bits (788), Expect = 5e-83
Identities = 299/1259 (23%), Positives = 523/1259 (41%), Gaps = 92/1259 (7%)
Query: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
SY GL PG YE L ++ +T P T S +
Sbjct: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
Query: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
Query: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
Query: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
Query: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
Query: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
Query: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
Query: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
Query: 1241 LEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
Y V+++ + P++ + + +P DL + +G D +R+ W + +F+
Sbjct: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA-YEHFV 1378
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
++ V E L++ S AV + L T Y VS+ V + + L T +
Sbjct: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKE 1438
Query: 1360 SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
G ++ SDIT SF + W+A + I + E + + + ++ L
Sbjct: 1439 PEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGL 1498
Query: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVAATPTSLLISWDAPAVTVR 1476
P T+++V + L + I +T +P +L + P +SW A
Sbjct: 1499 PPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISDINPYGFTVSWMASENAFD 1557
Query: 1477 YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ +T ++G QEFT+ G++ + GL G+ Y + V T +KP+
Sbjct: 1558 SFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT----QGHQTKPLRA 1613
Query: 1537 NYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVTTTPKNGPGPTKTKTAGPD 1593
TE + + + V+D + + W + ++ T K P + P+
Sbjct: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE-PLEITLLAPE 1672
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653
+T I GL+ EY + +Y + SQ + A T + +P ++ F+ +T S + W
Sbjct: 1673 RTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWR 1731
Query: 1654 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1713
P Q+ +R+ P P + + + + L+ +Y VS+ A+K S P
Sbjct: 1732 APTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEP 1790
Query: 1714 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP 1773
G TT + P + T++ W+ T+ + + + I RT+
Sbjct: 1791 VSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-SYTGEKVPEITRTVSG 1847
Query: 1774 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 1833
+ Y +T L+P T+Y + ++ +SS + +T +D+P +L + L++W
Sbjct: 1848 NTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTW 1907
Query: 1834 QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
+PPRA +TGY++ YE +EV+ P T ++ L P T YT + AL +S
Sbjct: 1908 RPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTHYTAKIQALNGPLRS 1964
Score = 272 bits (695), Expect = 3e-72
Identities = 300/1234 (24%), Positives = 480/1234 (38%), Gaps = 81/1234 (6%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
Query: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
Query: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
S P + + P DL+ + ++ + W P + + + YS + +
Sbjct: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
+ + + VL L PG EY V +++ +H+S P R + T + +++ +
Sbjct: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090
Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
++W A + I+ + R VP S ++ + L T Y VSI +
Sbjct: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150
Query: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
+P+L + ST + P EVV A +L ++W AP Y+ I E Q
Sbjct: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
TVPG + + GLK YTIT+ VT S+ P+S+ T E+ + VT
Sbjct: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265
Query: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
+V +++ + W + + + T M I GL+ Y V+
Sbjct: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325
Query: 1612 VYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1670
++ + ++PL VT +P DL ++V L WT + + ++V
Sbjct: 1326 LHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVN 1385
Query: 1671 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1730
K + + L +V + GL AT Y VS+Y + + P +
Sbjct: 1386 KVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRT-PVLSAEASTAKEPEIGNL 1444
Query: 1731 RVTDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDY 1789
V+D T + +SW F ++ + +N ++ I R+ I+GL P TD+
Sbjct: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504
Query: 1790 KIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
+YL L + R+ + A+T A+ NL P VSW +++
Sbjct: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVV 1564
Query: 1849 KPGS--PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQ 1906
G P+E E + GL G Y + V +++PL +
Sbjct: 1565 DSGKLLDPQEFTLSGTQRKLE--LRGLITGIGYEVMVSGFTQGHQTKPL--------RAE 1614
Query: 1907 LVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHG 1966
+VT P + + D T +G +L T+ + V + +
Sbjct: 1615 IVTEAEPEVDNLLVSDA----------------TPDGFRLSWTADE--GVFDNFVLKIRD 1656
Query: 1967 FRRTTPP---TTATPIRHRPRPYPPNVGE-EIQIGHIP---REDVDYHLYPHGPGLNPNA 2019
++ + P T P R R E EI++ I R + G
Sbjct: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEV 1716
Query: 2020 STGQEALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 2078
+ T+SW AP + I+ P+ T P V GT T L L G Y
Sbjct: 1717 IFSDITENSATVSWRAPTAQVESFRITYVPI-TGGTPSMVTVDGTKTQTRLVKLIPGVEY 1775
Query: 2079 NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPT 2112
+ + A+K EE V S L+ P+
Sbjct: 1776 LVSIIAMKG------FEESEPVSGSFTTALDGPS 1803
Score = 252 bits (644), Expect = 3e-66
Identities = 272/1173 (23%), Positives = 470/1173 (40%), Gaps = 92/1173 (7%)
Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
N Y+I LKP YE LIS R D + S P TG P + L
Sbjct: 856 NQYSIGNLKPDTEYEVSLIS---------RRGDMS----SNPAKETFTTGLDAPRN-LRR 901
Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---ATSVNIPDL 780
S+ T +S + W + + +R++Y GD + +D+P + T + L
Sbjct: 902 VSQ-----TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAE-VDVPKSQQATTKTTLTGL 955
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
PG +Y + V + ED E + + + T D P D V + +TS+ + W P A
Sbjct: 956 RPGTEYGIGVSAVKEDKESNPA-TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDR 1014
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YR+ YS G + LP S L L+PG +YN+ + A + +S P ++ T
Sbjct: 1015 YRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-- 1071
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
+ P +L EV + + WT + A + + V N E + L + +
Sbjct: 1072 ----EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKV-EAARNLTVPGSL 1126
Query: 961 FA-EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRWT 1018
A ++ GL Y ++ V G + L+A+ +T V E L + WT
Sbjct: 1127 RAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWT 1186
Query: 1019 PPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGN-QESP 1076
P + + V + Q P + L L+ A+ YT+++ + + +P
Sbjct: 1187 APEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTP 1246
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSD 1134
+ V T P TEV+ + + WT F + V+ + E +T
Sbjct: 1247 LSVEVLTEEVPDMGNLTV-TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVP 1305
Query: 1135 SG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
S+ + GL G Y T+ G P+ +VVT P D V
Sbjct: 1306 GSLRSMEIPGLRAGTPYTVTLHGEVRGHST-RPLAVEVVTEDLPQLG-------DLAVSE 1357
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS----------PGLE 1242
V W+ G R+ T + + + +V ++ NL+ PGLE
Sbjct: 1358 VGWD--------GLRLNWTAADNAYEHFVIQVQEVNKVEAA-QNLTLPGSLRAVDIPGLE 1408
Query: 1243 ----YNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Y VS+Y ++ + V ++ P +L ++I P++ ++W I T
Sbjct: 1409 AATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFET- 1467
Query: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
F + + E +IS ++ ++ L P T+++V +S + + + T
Sbjct: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527
Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
L + SDI FTV W+A + + P+E + ++ + L
Sbjct: 1528 ALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELR 1587
Query: 1417 NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTV 1475
L G Y V + G + PL + +L V ATP +SW A
Sbjct: 1588 GLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVF 1647
Query: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-GRGDSPASSKPI 1534
+ + +T S E T+ + T I+GL+ +Y I +Y ++ GR S+ +
Sbjct: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGR-----RSQTV 1702
Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
S T + P ++ +D+ +NS +V W ++ V +R+T P G P+ G +
Sbjct: 1703 SAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGT-K 1761
Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTP 1654
T+ + L P VEY+VS+ A ES+P+ + T + P+ L +T + A+W P
Sbjct: 1762 TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQP 1821
Query: 1655 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--VVSGLMVATKYEVSVYALKDTLTSR 1712
+ Y + T ++ + EI ++V ++ L AT+Y + ++A K S
Sbjct: 1822 AIATVDSYVISYTGEK----VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSS 1877
Query: 1713 PAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK 1772
TT ++ PR T+ T ++WR ++TG+ + +G T + +
Sbjct: 1878 TITAKFTT--DLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDG-TVKEVIVG 1934
Query: 1773 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1805
PD SY++ L P T Y + LN RS+ +
Sbjct: 1935 PDTTSYSLADLSPSTHYTAKIQALNGPLRSNMI 1967
Score = 229 bits (584), Expect = 2e-59
Identities = 252/1125 (22%), Positives = 465/1125 (41%), Gaps = 74/1125 (6%)
Query: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT---IKGLKPGVVYEGQ 680
NS ++W + + I Y +++ P + G E +P + T + GL+PG Y
Sbjct: 907 NSITLEWRNGKAA-IDSYRIKYAPISG-GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIG 964
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
+ ++++ S P T N T TP V+E +S + W
Sbjct: 965 VSAVKE-------------DKESNPATINAATELDTP------KDLQVSETAETSLTLLW 1005
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ +R+ Y L + + LP TS + L PG++Y NV +E G
Sbjct: 1006 KTPLAKFDRYRLNYSLPT--GQWVGVQLPRNTTSYVLRGLEPGQEY--NVLLTAEKGRHK 1061
Query: 801 LILSTSQTTAPDAPP--DPTVDQVDDTSIVVRWSRPQAPITGYRI-VYSPSVEGSSTELN 857
+ + + AP + TV +V + + W+ + I V + ++ L
Sbjct: 1062 SKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLT 1121
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
+P + +V + L+ Y ++IY V + TPV+ + +TG P+ ++ E
Sbjct: 1122 VPGSLRAVDIPGLKAATPYTVSIYGVIQGYR-TPVLSAEASTGE-----TPNLGEVVVAE 1175
Query: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYY 974
V + + WT PE A + + V + E Q L + R+T ++ GL Y
Sbjct: 1176 VGWDALKLNWTAPEGAYEYFFIQVQEADTV-EAAQNLTVPGGLRST--DLPGLKAATHYT 1232
Query: 975 FKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRWTPPRAQITGYRLTVG 1032
+ V+ + PL+ + T+ + P NL + + + WT P + + V
Sbjct: 1233 ITIRGVTQDFSTTPLSVEVLTE-EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQ 1291
Query: 1033 LTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSS 1090
+ + V S+ + L+ + YTV+L ++G+ P A V T P
Sbjct: 1292 EADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLG 1351
Query: 1091 IPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIVVSGLTPG 1146
+ EV + + WT A F + V+ EA + +T ++ + GL
Sbjct: 1352 DLAVS-EVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAA 1410
Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT--NLHL-EANPDTGVLTVSWERSTTPDI 1203
Y +I + G P+++ + P NL++ + P++ +SW +T
Sbjct: 1411 TPYRVSIYGVIRGYR--TPVLSAEASTAKEPEIGNLNVSDITPES--FNLSW-MATDGIF 1465
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI 1263
+ I +N + ++E + + + L P ++ V + + + IS T
Sbjct: 1466 ETFTIEIIDSN-RLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATA 1524
Query: 1264 IP-AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
A+P +L ++I P V+W + +FLV D E ++S +
Sbjct: 1525 TTEALPLLENLTISDINPYGFTVSWMASENA-FDSFLVTVVDSGKLLDPQEFTLSGTQRK 1583
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT-GIDFSDITANSFTVHWIAP 1381
+ L L+ G Y V VS + H++ PLR T + + SD T + F + W A
Sbjct: 1584 LELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTAD 1643
Query: 1382 RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLI 1441
+ ++ P E + + +T L TEY + + ++ S +
Sbjct: 1644 EGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVS 1703
Query: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
+T P+++ T S +SW AP V +RITY G +P TV G+K+
Sbjct: 1704 AIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKT 1762
Query: 1502 TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
+ L PGV+Y +++ A+ G +S +P+S ++ T +D PS + ++ D+ +
Sbjct: 1763 QTRLVKLIPGVEYLVSIIAMKGFEES----EPVSGSFTTALDGPSGLVTANITDSEALAR 1818
Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
W P+ + V Y ++ T + P T+T + + E + L+P EY + ++A+ +S
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSG--NTVEYALTDLEPATEYTLRIFAEKGPQKS 1876
Query: 1622 QPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681
+ T + +P DL T+V + W PP +TGY + + G +KE+ +
Sbjct: 1877 STITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVG 1934
Query: 1682 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
PD++S ++ L +T Y + AL L S Q + TT+ + P
Sbjct: 1935 PDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
Score = 226 bits (576), Expect = 2e-58
Identities = 208/935 (22%), Positives = 382/935 (40%), Gaps = 29/935 (3%)
Query: 990 TAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSV 1048
+ + +++ P +L T+ TV + W ++T Y + T G Q+ V
Sbjct: 616 SGEDCSEVSPPKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQ 674
Query: 1049 SKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT 1108
+ ++ L+P EY + + AI N++S + T P + + + ET++ + W
Sbjct: 675 TSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKS-IKETSVEVEWD 733
Query: 1109 PAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
P I F+ + GE + + S +GL PG EY ++ ++++ R
Sbjct: 734 PLD-IAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNT-R 791
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
+ T L P+ + ++ DT L ++W + +I G +T G+
Sbjct: 792 GPGLKRVTTTRLDAPSQIEVKDVTDTTAL-ITWFKPLA-EIDGIELTYG-IKDVPGDRTT 848
Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
+ D++ + NL P EY VS+ + + D S P +T + P +LR + ++
Sbjct: 849 IDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNS 908
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVS 1339
+ + W + + ++ ++Y+P+ D AE+ + S A LT L PGTEY + VS
Sbjct: 909 ITLEWRNGKAA-IDSYRIKYAPISGG-DHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVS 966
Query: 1340 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
+V E ES P T LD+P + S+ S T+ W P A YR+ + +G
Sbjct: 967 AVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLP--TG 1024
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVA 1458
+ ++P + S L L PG EY V + A GR +S P + + + +L V
Sbjct: 1025 QWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTE 1084
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
L ++W A ++ I E + TVPGS I GLK YT+++
Sbjct: 1085 VGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSI 1144
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
Y V +P S S E ++ V +V +++ + W + +
Sbjct: 1145 YGVIQGYRTPVLSAEASTG---ETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQE 1201
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637
+ + T + GL+ Y +++ + PL V+ +P +
Sbjct: 1202 ADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGN 1261
Query: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATK 1697
L T+V+ +L WT P+ + ++V ++ + + S+ + GL T
Sbjct: 1262 LTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTP 1321
Query: 1698 YEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD 1757
Y V+++ ++RP V T E++ V++ + ++W F +
Sbjct: 1322 YTVTLHGEVRGHSTRPLAVEVVT-EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
Query: 1758 AVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816
N Q T+ +R+ I GL+ T Y++ +Y + R+ + +ASTA +
Sbjct: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE 1440
Query: 1817 -SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1875
NL TP S +SW + I+ V A I+GL P
Sbjct: 1441 IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP 1500
Query: 1876 GTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTL 1910
T++ +Y+ L + +++ + T+ LP L L
Sbjct: 1501 STDFIVYLSGLAPSIRTKTISATATTEALPLLENL 1535
Score = 153 bits (386), Expect = 2e-36
Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
T A + T+ ++ V W + + + S + E L T +
Sbjct: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
Query: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
Query: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
Query: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
+V D +S + +LSP Y + + S I TI P P D +
Sbjct: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991
Query: 1281 DT 1282
DT
Sbjct: 1992 DT 1993
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 356 bits (913), Expect = 2e-97
Identities = 266/878 (30%), Positives = 413/878 (47%), Gaps = 56/878 (6%)
Query: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
Query: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
Query: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
Query: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
Query: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
Query: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
SV + ++S+ + P + L F+++ ++ +TW+ PS ++ YSP
Sbjct: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
EE++ E+S+ + VL L P TEY+V++ +V+ S P+ G TG+D P I
Sbjct: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871
Query: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
S++T +S V W P A+ YR+ + P GR VP++ T+T L P TEY
Sbjct: 872 ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930
Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
+S+ ++ GREES + T D P DL TPT L+ W AP V Y I T+
Sbjct: 931 ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
G + V G + L P YT T+YA G P +S IS N+ T +D
Sbjct: 991 AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
P+ + ++V S + W P + + Y T K+ G K + T + +EGL
Sbjct: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTT----IPAPTD 1637
+Y V + A + S + TA TT P P D
Sbjct: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFTTGGRVFPHPQD 1137
Score = 298 bits (763), Expect = 4e-80
Identities = 210/717 (29%), Positives = 336/717 (46%), Gaps = 24/717 (3%)
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
++PP +L + D + + W+ +T Y I+ PT G L++ V D S T
Sbjct: 326 VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
L PGL YN+SVY V + S+PI+ + + P L+F I T+ V W P S
Sbjct: 382 ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440
Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
+ + + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P
Sbjct: 441 SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498
Query: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
T +D PT I D++ V WI PRA + +++ G R+ +
Sbjct: 499 SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
++ L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD
Sbjct: 559 YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
V+ Y++ Y G E VP G + AT++ L PG +Y + + AV +
Sbjct: 619 AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673
Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
S P ++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T
Sbjct: 674 QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS 1649
D+T T+ L+P EY++SV A+ +S A T + L F+ VT +S++
Sbjct: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
Query: 1650 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1709
W+ P+ + +P+++ M E++L V+ GL AT+Y V++ A+ T+
Sbjct: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
Query: 1710 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1769
TS P G +TT + PP+ +++ T+ ++ +SW + ++V P
Sbjct: 852 TSEPIVGSITT--GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSS 909
Query: 1770 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL 1829
+ V +TIT L P T+Y+I L ++ S + TA+D P +L TP
Sbjct: 910 VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
Query: 1830 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA-TITGLEPGTEYTIYVIA 1885
L+ W+ P + Y+I ++ GV+E + L P T YT + A
Sbjct: 970 LLQWKAPVGEVENYVIVLTHFAVAGETILV---DGVSEEFRLVDLLPSTHYTATMYA 1023
Score = 271 bits (692), Expect = 7e-72
Identities = 211/831 (25%), Positives = 361/831 (43%), Gaps = 24/831 (2%)
Query: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 558 QYSVQALRPGSRYEVSVSAVRGTNESDSA-TTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
Query: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
SVP + + P DL T ++ + W S + ++ + ++P + +E++
Sbjct: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTP--SSGIASEVT 731
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
+ + LT+L PG EY++SV++ + +S TG + + FS +T++S
Sbjct: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
+ W P + + P E + ++ L L P TEY+V++VA++G
Sbjct: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
S ++G +T D P+D+ + T S+++SW P + YYR++Y T +
Sbjct: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910
Query: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
VP + + TI+ L P +Y I++ +V GR + S+ I T +D P + T++
Sbjct: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966
Query: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
++W V Y + T G +T E + L P+ Y ++YA
Sbjct: 967 TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024
Query: 1616 NPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
N S + T + P +L ++VT S W PP ++ Y +T K G
Sbjct: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSR 1082
Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
KE+ + + + + + GL+ T Y V + A +DT S TT V P
Sbjct: 1083 KELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
Score = 267 bits (683), Expect = 8e-71
Identities = 211/801 (26%), Positives = 359/801 (44%), Gaps = 33/801 (4%)
Query: 1098 VTETTIVITWT-PAPRIGFKLGVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
+++ +I + W P + + +P+ G + + V D + ++ L PG+ Y ++
Sbjct: 337 ISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVY 396
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
+ PI KV T LS P L + +T V V WE + G+ I+ P N
Sbjct: 397 AVISNI-LSLPITAKVATHLSTPQGLQFKTITETTV-EVQWEPFSF-SFDGWEISFIPKN 453
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLR 1274
+ G + V +D +S L PG EY V+V +K+ S P S ++ + PT +
Sbjct: 454 NEGGVIAQ--VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQIL 511
Query: 1275 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
++ V W PP + + L++Y V E + P + + L PG+ Y
Sbjct: 512 VRDVSDTVAFVEWIPPRA-KVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRY 570
Query: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
VSVS+V +ES + T +D+P + TA S + W A + Y++ +
Sbjct: 571 EVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYST 630
Query: 1395 EHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+G E VP TLT+L PGTEY V I A+ ++S T D
Sbjct: 631 --LAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDS 688
Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510
PRDL V A++ TS+ + W + + +YRIT+ + G + E TVP +++ T++ L+P
Sbjct: 689 PRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVTVPKDRTSYTLTDLEP 746
Query: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVT 1570
G +Y I+V A GR S S+ +R S + + V +S+++ W S P
Sbjct: 747 GAEYIISVTAERGRQQSLESTVDAFTGFRPI----SHLHFSHVTSSSVNITWSDPSPPAD 802
Query: 1571 GYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630
+ +P++ + + + GLQP EY+V++ A + + S+P+V + T
Sbjct: 803 RLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITT 862
Query: 1631 TIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS 1690
I P D+ + VT S+ W+PP YRV P + G + + + ++
Sbjct: 863 GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTVTEFTIT 921
Query: 1691 GLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1749
L AT+YE+S+ +++ S R V T ++N P T+ T T + W+
Sbjct: 922 RLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPTEALLQWKAPVG 978
Query: 1750 TITGFQVDAV--PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
+ + + G+T + + + R + L P T Y +Y N S +
Sbjct: 979 EVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYATNGPLTSGTIST 1035
Query: 1808 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
+ ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E++ T
Sbjct: 1036 NFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAED--TW 1093
Query: 1868 ATITGLEPGTEYTIYVIALKN 1888
+ GL T+YT+ + A ++
Sbjct: 1094 IRLEGLLENTDYTVLLQAAQD 1114
Score = 245 bits (626), Expect = 3e-64
Identities = 220/851 (25%), Positives = 350/851 (41%), Gaps = 56/851 (6%)
Query: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
AV PP DLR I ++ + W P ++ T +++ Y P + + + V +
Sbjct: 325 AVAPPEDLRVAGISDRSIELEWDGPMAV--TEYVISYQPTALGGLQLQQRVPGDWSGVTI 382
Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI 1385
T L PG Y +SV +V S P+ + T L +P G+ F IT + V W +
Sbjct: 383 TELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSF 442
Query: 1386 TGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
G+ I P++ G +VP S T L PG EY+V++VAL + SP S
Sbjct: 443 DGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVS 501
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
TV D P + V + T + W P V + + YG GG F + S ++
Sbjct: 502 TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSV 561
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
L+PG Y ++V AV G +S +++ + TEID P ++V S+ ++W S
Sbjct: 562 QALRPGSRYEVSVSAVRGTNESDSATT----QFTTEIDAPKNLRVGSRTATSLDLEWDNS 617
Query: 1566 SSPVTGYRVTTTPKNGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+ V Y+V + G + + GP T T+ L P EY V + A S +S
Sbjct: 618 EAEVQEYKVVYSTLAGEQYHEVLVPRGIGPT-TRATLTDLVPGTEYGVGISAVMNSQQSV 676
Query: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
P A T + +P DL T + TS+S WT + + YR+ TP +G E+ +
Sbjct: 677 PATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPK 734
Query: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1742
D +S ++ L +Y +SV A + S + V P + T +++ I
Sbjct: 735 DRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSSSVNI 792
Query: 1743 SWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 793 TWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVT 852
Query: 1802 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVP 1859
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G VVP
Sbjct: 853 SEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVP 912
Query: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 1919
VTE TIT L P TEY I + +++ ++SE ++ TL H + P
Sbjct: 913 NT---VTEFTITRLNPATEYEISLNSVRGREESE------------RICTLVHTAMDNPV 957
Query: 1920 IL---DVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTA 1976
L ++ T + G I L + ++ + EE P T
Sbjct: 958 DLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHY 1017
Query: 1977 TPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAS--TGQEALSQTTISWA 2034
T + P I D P N AS T Q AL ISW
Sbjct: 1018 TATMYATN--GPLTSGTISTNFSTLLD---------PPANLTASEVTRQSAL----ISWQ 1062
Query: 2035 PFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKV 2093
P + + Y+++ TD + V T L GL Y ++++A +D +
Sbjct: 1063 PPRAEIENYVLTYK--STDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSI 1120
Query: 2094 REEVVTVGNSV 2104
T G V
Sbjct: 1121 TSTAFTTGGRV 1131
Score = 245 bits (626), Expect = 3e-64
Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
Query: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
Query: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
Query: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
Q G VV + T L+P EY +S+ +V+ +ES I + A+ P DL
Sbjct: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Query: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
TNI P + W AP ++ ++ + V E + + L +LLP T Y
Sbjct: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017
Query: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
++ + S + T LD P + S++T S + W PRA I Y + +
Sbjct: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075
Query: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
+ G +E V I L L T+Y V + A
Sbjct: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
Score = 194 bits (492), Expect = 1e-48
Identities = 142/551 (25%), Positives = 247/551 (44%), Gaps = 15/551 (2%)
Query: 1351 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
Query: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
Query: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
P ++ +++ L+P Y VSV A + ES T I AP +L+ T TSL
Sbjct: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
Query: 1651 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP----DSSSVVVSGLMVATKYEVSVYALK 1706
+W ++ Y+V + G L P ++ ++ L+ T+Y V + A+
Sbjct: 613 EWDNSEAEVQEYKVVYSTL--AGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM 670
Query: 1707 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP 1766
++ S PA + + PR VT ++ET+I++ W + I +++ P++G
Sbjct: 671 NSQQSVPA--TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIAS 728
Query: 1767 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTP 1826
+ T+ D SYT+T L+PG +Y I + +S +DA T S+L F T
Sbjct: 729 -EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTS 787
Query: 1827 NSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
+S+ ++W P I+ Y + A + GL+P TEY + ++A+
Sbjct: 788 SSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAV 847
Query: 1887 KNNQKSEPLIG 1897
SEP++G
Sbjct: 848 HGTVTSEPIVG 858
Score = 134 bits (338), Expect = 8e-31
Identities = 121/467 (25%), Positives = 191/467 (40%), Gaps = 35/467 (7%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
T S S + W I Y + + P + + E T+P SYT+ L+PG Y
Sbjct: 695 TASSETSISLIWTKAS-GPIDHYRITFTPSSGIA--SEVTVPKDRTSYTLTDLEPGAEY- 750
Query: 679 GQLISIQ-QYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
+IS+ + G Q+ S T + TG F P+ + + +T+SS
Sbjct: 751 --IISVTAERGRQQ-----------SLESTVDAFTG----FRPI--SHLHFSHVTSSSVN 791
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
++W S + Y +E +E + L +T + L P +YIVN+ +
Sbjct: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
Query: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
I+ S TT D P D T+ V S++V WS P A YR+ Y P+ G
Sbjct: 852 TSEPIVG-SITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSV 910
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
+P T T++ L P +Y I++ +V +ES + T + +P DL
Sbjct: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-------AMDNPVDLIATN 963
Query: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T + + W P V Y + + + GE +S + L P Y +
Sbjct: 964 ITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEE--FRLVDLLPSTHYTATM 1021
Query: 978 FAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRG 1037
+A + S ++ +T LD P NL T + L+ W PPRA+I Y LT T G
Sbjct: 1022 YATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKST-DG 1080
Query: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
++ V + L L ++YTV L A + S + FTT
Sbjct: 1081 SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTT 1127
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 342 bits (877), Expect = 2e-93
Identities = 370/1525 (24%), Positives = 602/1525 (39%), Gaps = 154/1525 (10%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W+ P + +Y++ + P G +E T+ G + ++GLK G
Sbjct: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746
T++ + T+ + + GE T + + VT +IT +S W SA
Sbjct: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
Query: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
V G+RV ++ + + +LP A I +L P KY ++V+ GE + +
Sbjct: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
Query: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
T VD+ + ++ V W + YR+VY P G +P T S
Sbjct: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T +
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
W P V GY+V P G+ + + + L G TY VF + G ES
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
Query: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035
PL Q+ T L T + ++ E D +LV W+ RA R +
Sbjct: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
Query: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093
+++GP + L P +E+ ++ K + LQ +++P
Sbjct: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
Query: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136
Y T T + + + + G+RP EAP + D G
Sbjct: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
Query: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179
+ + P + Y + + R + + N V P L P+N
Sbjct: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
L + VSW + + Y++ P +G G E V ++S +L P
Sbjct: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
Query: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
EY V+VY+V +D+ S P+ T P L ++GP TM V W P T ++
Sbjct: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504
Query: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
+ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V S P+ R+ T
Sbjct: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415
L P + D+T ++ V W + Y +R+ PE +E V S S +L
Sbjct: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621
Query: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474
+L T Y VS+ A++ ESP + Q++T P +L++ T +WD A
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530
V YRIT+ G +S E + G ++T L P Y +++ A+ + D S
Sbjct: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
Query: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
+ + I T+ K P +QV + NS++VKW P+S V YR+T P G G +T
Sbjct: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTS 1647
T G Q + ++ L+P Y ++V + P GE + T + +L+ + ++
Sbjct: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859
Query: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
L+ +W Y++ P GP + + + +++ ++ L T Y V+V +
Sbjct: 1860 LNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 1918
Query: 1708 TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI 1767
TL R +V + T ++ + W + ++V P +G P
Sbjct: 1919 EGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 1977
Query: 1768 QRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATT 1825
+ + P + R + L P T Y + L L + +P T P NLR T
Sbjct: 1978 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 2037
Query: 1826 PNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVTEATITGLEPGTEYTIY 1882
NSL V+W + Y I Y P + VP R V + L+P T Y I
Sbjct: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV---ILQPLQPDTPYKIT 2094
Query: 1883 VIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGN 1942
VIA+ + L G +T L LP N+H I D T + + P G
Sbjct: 2095 VIAVYEDGDGGHLTGNGRTVGL-----LPPQNIH---ISDEWYTRFRVSWDPSPSPVLGY 2146
Query: 1943 GIQLPGTSGQQPS---VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIG-H 1998
I +P VG+ + H P TT Y NV + G
Sbjct: 2147 KIVYKPVGSNEPMEAFVGEMTSYTLHNL---NPSTT----------YDVNVYAQYDSGLS 2193
Query: 1999 IPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQ 2057
+P D LY + L T Q + W+P + + Y + P GT + +
Sbjct: 2194 VPLTDQGTTLYLNVTDL----KTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEIT 2249
Query: 2058 FRVPGTSTSATLTGLTRGATYNIIV 2082
R G+ TS TGL+ Y + V
Sbjct: 2250 VR--GSETSHCFTGLSPDTDYGVTV 2272
Score = 288 bits (737), Expect = 4e-77
Identities = 295/1234 (23%), Positives = 501/1234 (40%), Gaps = 84/1234 (6%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y
Sbjct: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
Query: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844
+VNV EDG S+ L+ +TT AP + V S + W++ + YRI+
Sbjct: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
Query: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
Y P G S E+ P TL +L P +Y +++ + TP+ TG +
Sbjct: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
Query: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
+ V +PRDL+ + T + + W+ V Y V PV G Q + + +T
Sbjct: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
Query: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020
V GL G Y V A+ L + TT + +P +L + TD+++ WT
Sbjct: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
Query: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+ GYR++ L + N+ + NLQP ++Y +S+ A + E T
Sbjct: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136
G TT S E TE T+ +TW PAP + +++ RP +G + +V
Sbjct: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
Query: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
S V+ L P Y T+ + + G+ + + P NL ++P V+W
Sbjct: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E
Sbjct: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308
S P+ + + T + + G + + A SI NF S +
Sbjct: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225
Query: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364
+V ++ A+ + P TE+ ++ S+ + + P +G ++ TG+
Sbjct: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280
Query: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
+ I +F T + PRA G I ++ + + E
Sbjct: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340
Query: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463
+ ++A + + + ++S + P +L + T S
Sbjct: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400
Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523
+SW P+ +V Y++ Y G QEF V +++ + LKP +Y + VY+V
Sbjct: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458
Query: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583
S+P+ +T + + DV ++ V+W P TGY ++ P
Sbjct: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514
Query: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKF 1640
PT+ K GP +M + L P EY V+V A S+P+ VT +P P DLK
Sbjct: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
Query: 1641 TQVTPTSLSAQWTPPNVQLTGYRVRV-TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699
VT ++++ W P ++ Y VR TP+E +KE+ + +S + L T Y
Sbjct: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSLKDLFSQTLYT 1631
Query: 1700 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1759
VSV A+ D S P TT V P ++T+ T +W ++ +++
Sbjct: 1632 VSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWA 1690
Query: 1760 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI------ 1813
P ++ + D + L P T Y++ + + + S +I + +
Sbjct: 1691 PFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQ 1750
Query: 1814 ---DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870
P NL+ T NSL V W P R+ Y I Y+ E +
Sbjct: 1751 APKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVL 1810
Query: 1871 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904
L+P T YTI V +L + + + GR KT L
Sbjct: 1811 QKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844
Score = 281 bits (719), Expect = 5e-75
Identities = 240/929 (25%), Positives = 404/929 (43%), Gaps = 39/929 (4%)
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L
Sbjct: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444
Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
+P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G
Sbjct: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ L +P + E R G V ++ L P EY T+Q + + V +V
Sbjct: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PL P +L L + + V WE P I T + +E V ++
Sbjct: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW
Sbjct: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676
Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES
Sbjct: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734
Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
L G ++T P + + T+NS TV W + YRI + P G
Sbjct: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
+ + +NS+ L L P T Y +++ +L E + G+ T + R+L V
Sbjct: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV
Sbjct: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
V GD +S R +QV + NS+ V+W P+ PV YRV +P
Sbjct: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637
+G P+++ + + +E L P Y V++ A GE P Q P +
Sbjct: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030
Query: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696
L+ T SLS W + + YR+ +P P+ E P ++V++ L T
Sbjct: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 2089
Query: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
Y+++V A+ + G T+ + PP+ ++D T +SW + G+++
Sbjct: 2090 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 2148
Query: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816
P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T
Sbjct: 2149 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207
Query: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876
++L+ ++ V W P RA T Y +K P R R T TGL P
Sbjct: 2208 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 2265
Query: 1877 TEYTIYVIALKNNQKSEPLIGRKKTDELP 1905
T+Y + V N + + ++ T P
Sbjct: 2266 TDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
Score = 262 bits (670), Expect = 3e-69
Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%)
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+AP + + + S V W+ P + Y++ Y P G E + S L DL+
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P
Sbjct: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498
Query: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
A TGY + PV P E RL + N ++T L P Y V AV H S
Sbjct: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554
Query: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
+P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V
Sbjct: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
S + L++L + YTVS+ A+ ESP T TT + TEVT
Sbjct: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
TW + + G + + T D ++V L P Y +I +
Sbjct: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733
Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
G ER PI+ P S P NL + N + LTV W+ + + YRIT P+
Sbjct: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
G +GN + Q+S L P Y ++V ++ D E ++ + +
Sbjct: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849
Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
LR + T+ V W + + + Y+P + + I + N +L NL P T
Sbjct: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
Y V+V VY + + +T + + + T NS V W + YR+
Sbjct: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967
Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
+ P + VP + + L L P T Y V++VAL + E +P ++
Sbjct: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027
Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+
Sbjct: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
P Y ITV AV GD ++ N RT + P + ++D V W PS SP
Sbjct: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142
Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL
Sbjct: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200
Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
T TDLK Q+ + +W+P T YR++++P + T +EI + +S
Sbjct: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 2258
Query: 1689 VSGLMVATKYEVSVY 1703
+GL T Y V+V+
Sbjct: 2259 FTGLSPDTDYGVTVF 2273
Score = 213 bits (543), Expect = 1e-54
Identities = 155/567 (27%), Positives = 252/567 (44%), Gaps = 17/567 (2%)
Query: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
A PP DL F+ + + W+P ++ ++ + Y +++V + + S +VVL
Sbjct: 631 AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688
Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383
++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W
Sbjct: 689 SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
+ YRI + P G RE P ++ TL NL P T+Y VS++ L G
Sbjct: 749 RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807
Query: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
+T V PRDL V T +++ +SW V+ Y +TY G QE TV G +
Sbjct: 808 AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866
Query: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
+ GLK G Y ++V A+ +G GD+ E P + D+ D SI
Sbjct: 867 NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922
Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
W + V GYRV+ T K D IE LQP +Y +SV+A SG
Sbjct: 923 AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982
Query: 1620 ESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678
E +PL A T + + LK + T ++ W P ++ YRV P + G
Sbjct: 983 EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGR-GKQMVA 1041
Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
+ P +S V+ L T Y+++V + + QG TT PR + +D T +
Sbjct: 1042 KVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101
Query: 1739 TITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
+ ++W + G++V P + + + P + + L+ GT YK+ ++ +
Sbjct: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161
Query: 1798 DNARSSPVVIDASTAIDAPSNLRFLAT 1824
D SSP+V T + + + L++
Sbjct: 1162 DGGESSPLVGQEMTTLSDTTVMPILSS 1188
Score = 200 bits (508), Expect = 2e-50
Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)
Query: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
P + +QW QP + YIL ++P R KE + +N + L P Y
Sbjct: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
+++Q H TS PVT VT PL + + ++T S+ V
Sbjct: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
Query: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE
Sbjct: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
Query: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
+ + T AP + + +V W + ++ YRI ++P E L
Sbjct: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
Query: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
N++ +L P Y ++I A+ ++ + +I E TT P+S PR+
Sbjct: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
Query: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
LQ T +T+ W P V YR+ P G R + L P
Sbjct: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
Query: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L
Sbjct: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
G + + + LRNLQP + YTV++V + + + + TL G
Sbjct: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
++ YN T ++ + W PAP + V S P + T S SIVV G
Sbjct: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P Y V + + DG+ +P + + P S P NL + T L+V+W+ +
Sbjct: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
P + YRI +PT G+ ++E V +++ L P Y ++V V +D +
Sbjct: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
++ + + PP ++ ++ RV+W P PS + + + Y PV + E + +
Sbjct: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
+ L NL P T Y V+V + Y+ S PL + T + T + I ++F V
Sbjct: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222
Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
W +P T YR++ P R +E V S S T L+P T+Y V++ E
Sbjct: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280
Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
P + + + +TV P + TP
Sbjct: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304
Score = 192 bits (487), Expect = 4e-48
Identities = 294/1314 (22%), Positives = 508/1314 (38%), Gaps = 144/1314 (10%)
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963
+ V P +L +EV+ V + W P S VTGY+V + P+ G L + + T
Sbjct: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011
V LS Y V A+ S+P++ + T+ +D ++ F V+ + S
Sbjct: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
Query: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051
+ + RA +I+ R+ + L T + + ++ +++ +
Sbjct: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
Query: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
P R N A Y + + KG++ + PK + T + + ++ + +
Sbjct: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
Query: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
I +G K VR A + ++ + + T + ++ A
Sbjct: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
I K P P +L G T +W ++ Y IT G + + V
Sbjct: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282
A +S +L P Y V+V +D S+P++ +T P +L+ T+ D+
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342
++TW P + + + Y PV E E++ P+ L NL+P T+Y VSV Y
Sbjct: 739 FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796
Query: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
TPL G T +P + SD T ++ + W + Y + + P G
Sbjct: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855
Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458
+E V + L L GT+Y +S+ AL L G+ +T+ + P+DL
Sbjct: 856 TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
T TS+ W + VR YR+++ + E +P I L+P Y I+V
Sbjct: 916 ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
+A G+ +P++ + TE+ + S+ ++V + +N++ V W P+ V YRV
Sbjct: 976 FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA 1634
P +G G P T ++ LQP Y ++V GE + L Q + TT +
Sbjct: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089
Query: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
P +LK + T +S W P ++ GY+V P + E+ + P ++VV+ L
Sbjct: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149
Query: 1695 ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGF 1754
T Y+V+V+ + D S P G +T ++TT+ + E +T
Sbjct: 1150 GTTYKVNVFGMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRA 1196
Query: 1755 QVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDAST 1811
+ D V +G I R VRS+ I+ + D K L + +
Sbjct: 1197 EADIVLLVDGSWSIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNA 1255
Query: 1812 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
D S L+ +A P +TG + + + + + RPR IT
Sbjct: 1256 HRDKKSLLQAVANLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLIT 1308
Query: 1872 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKT 1930
+ + LK+ IG K DE+ +++ + H + D S +
Sbjct: 1309 DGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIV 1368
Query: 1931 PFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYP 1987
+T + N ++ PG + PS ++ E FR + P + + R++ YP
Sbjct: 1369 DDLT---INLCNSVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYP 1421
Query: 1988 PNVG--EEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQ----------------- 2028
+ G +E + + V L P + S ++ S+
Sbjct: 1422 VSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLN 1481
Query: 2029 ------TT--ISWAPFQDTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATY 2078
TT + W P + YI+S PV E P + R+ T LT L Y
Sbjct: 1482 IYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEY 1541
Query: 2079 NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2132
+ V+A+ H + E VTV V L +P D D V+H + WE
Sbjct: 1542 AVTVQAV----LHDLTSEPVTV-REVTLPLPRPQDLKLRD---VTHSTMNVFWE 1587
Score = 161 bits (407), Expect = 8e-39
Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
E +S + I+QE + VP P+DL F EVT W+P V Y +
Sbjct: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002
E P S +T ++ L P Y V A S PL ++TT+ AP N
Sbjct: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062
L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y
Sbjct: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
Query: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119
VS++ + TG T + G+ ++ T +T+ ++W+ AP + +
Sbjct: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
Query: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176
P GGE +EVT D+ + V+ GL G +Y ++ L DA +
Sbjct: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232
P +L + DT + ++ S + GYR++ + + N E+ +H
Sbjct: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
+NL P +Y +SV+ E P++ D L+ +TMRVTW P P
Sbjct: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020
Query: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350
+ N+ V Y P + ++ VA+ + P+ + VL L P T Y ++V +Y+ E
Sbjct: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
Query: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
+G T SP + SD T +SF V W + GY++ HP R E V
Sbjct: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
Query: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449
N++ L L GT Y V++ + +G E SPL+ + +T+SD
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179
Score = 155 bits (391), Expect = 6e-37
Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S +S Y + W P S + E + G N+ + L P +YE +SI E
Sbjct: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D + + P+ TT + V T++S V W AS V +R+ Y+
Sbjct: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788
Query: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
S Q + SV + L P Y + V + DGE + +T +
Sbjct: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848
Query: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
+ V +++ VRW + Y++ Y+P+ G + +P N L +LQP
Sbjct: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908
Query: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
Y +T+ V + T+ T R+ R++Q T + + W P V
Sbjct: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
YRV PV+ + + + NT + L P Y + A+ E P AQ +
Sbjct: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021
Query: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
T P NL+ ET +++ V W + YR+ T +Y P +
Sbjct: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W
Sbjct: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138
Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+P+P +G+K+ +P E + S + L P Y + D P+
Sbjct: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 2197
Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
++ T T+L + DT V W S T YR+ +P +G +G E V
Sbjct: 2198 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 2251
Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
++S F LSP +Y V+V+ +VK+ P P PPP
Sbjct: 2252 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306
Score = 147 bits (370), Expect = 2e-34
Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)
Query: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
EQ L + P P D + +V WS + Y I Y + +
Sbjct: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ +
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
Query: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
T I WT V YR+ PV GE + + L P Y V
Sbjct: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
Query: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035
PLT T+ P +L+ + T ST+ + W+ ++ Y +T
Sbjct: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
Query: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094
G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS
Sbjct: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
Query: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
++T+T+I WT AP R+ +K GE + + D+ ++ L P +
Sbjct: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208
Y ++ E + P+ T LS + + V+W + + YR+
Sbjct: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
Query: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266
P +G + V +S L P Y+++V + E S T
Sbjct: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P DN VVL
Sbjct: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
L GT Y V+V +++ ES+PL G++ T L T
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
Score = 66.6 bits (161), Expect = 3e-10
Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
+L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L
Sbjct: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916
+ LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q
Sbjct: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
Query: 917 EVT 919
V+
Sbjct: 134 SVS 136
Score = 65.5 bits (158), Expect = 6e-10
Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 7/118 (5%)
Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
E+D PS + + +N++ + W P+ GYR+T P GPTK T TE +
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
Query: 1601 GLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653
L P EYVV++ + + ES P+ +QT +T P T++ S+SA WT
Sbjct: 83 ELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSA-WT 139
Score = 58.9 bits (141), Expect = 5e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)
Query: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108
L P +EY V++ + +ES G T+Q GSS P + +T I V WT
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
Score = 53.5 bits (127), Expect = 2e-06
Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
V PP+DL F I +T+ ++WA P + + + P + E ++S S +L+
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353
L+P TEYVV+++S E ES P+ G+
Sbjct: 83 ELVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+D P+ ++F I N+ + W P I GYRI P G +E + S L+
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
Query: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443
L P TEYVV+I + + EES +IGQ
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 48.5 bits (114), Expect = 7e-05
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 1624 LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+
Sbjct: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
Query: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1719
++ ++S L+ T+Y V++ + + S P G +T
Sbjct: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
Score = 45.1 bits (105), Expect = 8e-04
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E
Sbjct: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259
+ A + L P EY V++ + + +ESVP+
Sbjct: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
Score = 45.1 bits (105), Expect = 8e-04
Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
+ Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
Query: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
GS L++ ++++ DL +Y I++ A++ S P+ I ++T
Sbjct: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
Score = 45.1 bits (105), Expect = 8e-04
Identities = 25/99 (25%), Positives = 45/99 (45%)
Query: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1865
++ ++ PSNL + + + ++W P + +TGY + + R+ P
Sbjct: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
Query: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904
T ++ L TEY I V A+K SEP+ +KT +
Sbjct: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)
Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
LL+ D P DL ++ +SW P + YRIT T + P +EFT+
Sbjct: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
Query: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542
S + +S L P +Y +T+ + TG P KP +TEI
Sbjct: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
Query: 1543 DKPSQMQVTDV 1553
K S TD+
Sbjct: 131 QKCSVSAWTDL 141
Score = 42.7 bits (99), Expect = 0.004
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 1813 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1872
+D PS+L F N++ +SW P I GY I + P + TE ++
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
Query: 1873 LEPGTEYTIYVIALKNNQKSEPLIGR 1898
L P TEY + + + ++S P+IG+
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 36.2 bits (82), Expect = 0.38
Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1705 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1763
L L + A +++++E V PP E T+ +SW + I G+++ P
Sbjct: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
Query: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1806
+ T+ ++ L P T+Y + + + ++ S PV+
Sbjct: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
Score = 36.2 bits (82), Expect = 0.38
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)
Query: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1775
+V+ E V PP + + + ++W +TG++V P G ++ P
Sbjct: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
Query: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1824
+ ++ L T+Y+I + + S P V ++ S +D +++ FL
Sbjct: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446
Query: 1825 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1870
S+ + ++ RA + + +E P +V R TE T+
Sbjct: 447 GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494
Score = 35.0 bits (79), Expect = 0.85
Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P DL F + + V + W P + GYR+ V P G + + T ++
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001
L P Y + + ES P+ Q T + + T
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
Score = 33.5 bits (75), Expect = 2.5
Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
+SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E
Sbjct: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
Query: 798 EQ-----SLILSTSQTTAP 811
E L + T +T P
Sbjct: 102 ESVPVIGQLTIQTGSSTKP 120
Score = 32.7 bits (73), Expect = 4.2
Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
++S V E+ L+ + V + P +L + + + ++W+ V Y++
Sbjct: 312 IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544
S +V +T ++ L +Y I+V A+ G SS+PISI +T+
Sbjct: 371 MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423
Query: 1545 PSQMQV 1550
P ++QV
Sbjct: 424 PMKVQV 429
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 300 bits (767), Expect = 1e-80
Identities = 236/826 (28%), Positives = 376/826 (45%), Gaps = 35/826 (4%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
+ P +L + + V+W P + + ++VRY+ E E+ +
Sbjct: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
++ VLT L PG EY+V V + ES + +T +DSP + +T N TV W
Sbjct: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728
Query: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
RATI Y +R+ G RE V ++S LT L PG EY V + A G +ES
Sbjct: 729 DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
+ T D P++L T + +SWD T+ Y + Y T N +E V
Sbjct: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845
Query: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
+S+ ++GL+PG++YT+ V+A G + SK +TEID P + V +N
Sbjct: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901
Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
+V W P + + Y V T + G T+ G + + + GL+P +EY+V V+AQ +
Sbjct: 902 TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
Query: 1619 GESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678
ES+ A T + P +L+ + VT + WTPP+ Q+ GY +T + G +KE+
Sbjct: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGY--ILTYQFPDGTVKEM 1017
Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
L + + GL Y VS+ A K R ++ V TTL V
Sbjct: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKG---GRRSRNVSTTLSTV 1060
Score = 296 bits (757), Expect = 2e-79
Identities = 221/818 (27%), Positives = 369/818 (45%), Gaps = 28/818 (3%)
Query: 1082 FTTLQPGSSIPPYNTEV---TETTIVITWTPAPRIGFKLGVRPSQGGEAPR---EVTSDS 1135
FT L + P ++ TE +++++W P+ ++ L G E +V +
Sbjct: 254 FTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
S + GL PG +Y+ T++ +++ + +P T L+ + + L V W
Sbjct: 314 HSYEILGLLPGTKYIVTLRNVKN-EVSSSPQHLLATTDLAVLGTAWVTDETENS-LDVEW 371
Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-QSSCTFDNLSPGLEYNVSVYTVKDDK 1254
E +T ++ Y++ P GQ+ + +D +S L PG EY ++V ++ +
Sbjct: 372 ENPST-EVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGEL 430
Query: 1255 ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1314
E PI + PT++ + DT V+W P ++ + ++VRY+ + D E+
Sbjct: 431 EGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAV-IDKYVVRYTSA--DGDTKEM 487
Query: 1315 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1374
++ +++ VLT L PG Y V V + S T +DSP + +T N+
Sbjct: 488 AVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTA 547
Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
T+ W +ATI Y +R+ RE V ++S LT L PG EY V + A G
Sbjct: 548 TISWDPVQATIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGD 606
Query: 1435 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
ES T D P++L T +SWD + Y + Y GG + +E
Sbjct: 607 RESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGET--REV 664
Query: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554
V +S+ ++GL+PG++Y + V+A G +S K +T+ID P + V
Sbjct: 665 PVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQES----KKADTKAQTDIDSPQNLVTDRVT 720
Query: 1555 DNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1614
+N +V W P + + Y V T G T+ G +Q+ + GL+P VEY V V+A
Sbjct: 721 ENMATVSWDPVRATIDRYVVRYTSAKD-GETREVPVGKEQSSTVLTGLRPGVEYTVHVWA 779
Query: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
Q + ES+ A T I +P +L VT + + W P + Y V T G
Sbjct: 780 QKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGE 837
Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734
+E+ + + SS V++GL +Y V V+A K S+ A T + P+
Sbjct: 838 TREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDW 895
Query: 1735 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
TE T+SW TI + V A+G+T + + + S +TGL+PG +Y ++++
Sbjct: 896 VTENMATVSWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVW 954
Query: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1854
S A T +D P NLR A T + +++W PP A+I GYI+ Y+ P
Sbjct: 955 AQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTV 1014
Query: 1855 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
+E+ + GLE G Y + ++A K ++S
Sbjct: 1015 KEMQLGRED--QRFALQGLEQGATYPVSLVAFKGGRRS 1050
Score = 288 bits (736), Expect = 6e-77
Identities = 225/758 (29%), Positives = 346/758 (45%), Gaps = 30/758 (3%)
Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
P L L N + +L VSWE S+ D Y ++ P G++ + + V +Q S
Sbjct: 265 PQGLQLLKNTEDSLL-VSWEPSSQVD--HYLLSYYPL-GKELSGKQIQVPKEQHSYEILG 320
Query: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
L PG +Y V++ VK++ S P + T+ +++ V W P S ++
Sbjct: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVD 379
Query: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
+ +RY P+ +E VAE+++ S + +T L PGTEY ++V + + E P+
Sbjct: 380 YYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Query: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
+T +DSPT + +T ++ TV W +A I Y +R+ G +E V +S
Sbjct: 439 GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESST 496
Query: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1473
LT L PG Y V + A G + S T D P +L T + ISWD
Sbjct: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
Query: 1474 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
T+ Y + Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K
Sbjct: 557 TIDKYVVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KK 611
Query: 1534 ISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
N T+ID P + V +N +V W P + + Y V T + G T+ G +
Sbjct: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKE 669
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653
Q+ + GL+P +EY+V V+AQ ES+ A T I +P +L +VT + W
Sbjct: 670 QSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWD 729
Query: 1654 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1713
P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S+
Sbjct: 730 PVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKK 788
Query: 1714 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP 1773
A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 789 ADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPVGK 845
Query: 1774 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 1833
+ S +TGL+PG +Y ++++ N S A T ID P NL T N VSW
Sbjct: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
Query: 1834 QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1893
P +A I Y+++Y REV T +TGL PG EY ++V A K Q+S
Sbjct: 906 DPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQES- 962
Query: 1894 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP 1931
KK D Q P NL + + TP
Sbjct: 963 -----KKADTKAQTELDPPRNLRPSAVTQSGGILTWTP 995
Score = 263 bits (671), Expect = 2e-69
Identities = 183/640 (28%), Positives = 294/640 (45%), Gaps = 21/640 (3%)
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
Query: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Query: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
Query: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
Query: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
A T I +P +L +VT + W P + Y VR T G +E+ +
Sbjct: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGK 668
Query: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1742
+ SS V++GL +Y V V+A K S+ A T ++ P+ TE T+
Sbjct: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVTENMATV 726
Query: 1743 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1802
SW TI + V A + + + S +TGL+PG +Y ++++ S
Sbjct: 727 SWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
Query: 1803 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1862
A T ID+P NL T N+ VSW P +A I Y++ Y REV
Sbjct: 787 KKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKE 846
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1902
T +TGL PG EYT++V A K NQ+S+ + +T+
Sbjct: 847 QSST--VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE 884
Score = 240 bits (612), Expect = 1e-62
Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
Query: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
Query: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
Query: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
Query: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
Query: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
+QSS L PG+EY V V+ K ++ES + P +L + + V+W
Sbjct: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
Query: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
P + ++VRY+ E E+ + ++ VLT L PG EY+V V + ES
Sbjct: 906 -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
Query: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
+ +T LD P + S +T + + W P A I GY + + + G +E ++
Sbjct: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020
Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
L L G Y VS+VA G S + STV
Sbjct: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
Score = 223 bits (567), Expect = 2e-57
Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Query: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
Query: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
Query: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
Query: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
Query: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
Query: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
T +G+ + E V + SS L PG+EY V V+ K +ES + PP
Sbjct: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
+LR + + +TW PPS + +++ Y + V E+ + D L L
Sbjct: 977 RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033
Query: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
G Y VS+ + S + T G P D S + NS
Sbjct: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
Score = 145 bits (366), Expect = 4e-34
Identities = 149/599 (24%), Positives = 243/599 (40%), Gaps = 42/599 (7%)
Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
++ P +Q+ ++S+ V W PSS V Y ++ P K +Q I
Sbjct: 261 QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLT 1660
GL P +Y+V++ S P A T + T T SL +W P+ ++
Sbjct: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
Query: 1661 GYRVRVTPKEKTGP-MKEINLAPDS---SSVVVSGLMVATKYEVSVYALKDTLTSRPAQG 1716
Y++R P TG + E+ + S S ++GL T+Y+++V ++ L +P
Sbjct: 380 YYKLRYGPM--TGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPI-- 435
Query: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVR 1776
++ + P TE T T+SW I + V A+G T + + D
Sbjct: 436 LLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTK-EMAVHKDES 494
Query: 1777 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 1836
S +TGL+PG YK+Y++ N S +A T ID+P+NL T N+ +SW P
Sbjct: 495 STVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPV 554
Query: 1837 RARITGYIIKYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
+A I Y+++Y REV+ T +TGL PG EYT++V A K +++S
Sbjct: 555 QATIDKYVVRYTSADDQETREVLVGKEQSST--VLTGLRPGVEYTVHVWAQKGDRES--- 609
Query: 1896 IGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 1955
+K P + P NL + + +TV P G + + P
Sbjct: 610 --KKADTNAPTDIDSPK-NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVP- 665
Query: 1956 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGL 2015
VG++ T T +R Y +V + + D P
Sbjct: 666 VGKEQ-----------SSTVLTGLRPGME-YMVHVWAQKGDQESKKADTKAQTDIDSP-- 711
Query: 2016 NPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2075
N T + + T+SW P + T + + + D E + V +S LTGL G
Sbjct: 712 -QNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPG 770
Query: 2076 ATYNIIVEALKDQQRH-----KVREEVVTVGNSVNEGLNQPTDDSCFDPY--TVSHYAV 2127
Y + V A K Q K + ++ + N V + + + T +DP T+ Y V
Sbjct: 771 VEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV 829
Score = 79.3 bits (194), Expect = 4e-14
Identities = 100/425 (23%), Positives = 161/425 (37%), Gaps = 44/425 (10%)
Query: 1724 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITG 1782
V P+ ++ TE ++ +SW ++ + + + P + + Q + + SY I G
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
Query: 1783 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1842
L PGT Y + L + + SSP + A+T + T NSL V W+ P +
Sbjct: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDY 380
Query: 1843 YIIKY-EKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
Y ++Y G EV VP+ + ITGL PGTEY I V+ ++ + +P++
Sbjct: 381 YKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPIL---- 436
Query: 1901 TDELPQLVTLPHPNLHGPEILDVPSTV---QKTPFVTHPGYDTGNGIQLPGTSGQQPSVG 1957
L+G +D P+ V + T +D + + G
Sbjct: 437 --------------LNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG 482
Query: 1958 QQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNP 2017
H +T T P Y V E + D + P
Sbjct: 483 DTKEMAVHKDESSTVLTGLKP----GEAYKVYVWAERGNQGSKKADTNALTEIDSPA--- 535
Query: 2018 NASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 2077
N T + + TISW P Q T + + + D+E + V +S LTGL G
Sbjct: 536 NLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVE 595
Query: 2078 YNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVSHY 2125
Y + V A K D++ K T V + V E + + D + D Y V +
Sbjct: 596 YTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT 655
Query: 2126 AVGDE 2130
+ G E
Sbjct: 656 SAGGE 660
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 283 bits (723), Expect = 2e-75
Identities = 339/1511 (22%), Positives = 570/1511 (37%), Gaps = 237/1511 (15%)
Query: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
+S + W P+ +++++ KN G+ K +PGH + TI GL+P Y+ L
Sbjct: 2208 DSLSLSWTVPE-GQFDHFLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2264
Query: 684 IQQYGHQEVTRFDFT--TTSTSTPVTSNTVTGETTPFSPLVATSE--SVTEITASSFVVS 739
+G Q V T + T TP P+ E +VT+ T S +S
Sbjct: 2265 F--HGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLS 2322
Query: 740 WVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVY------- 791
W F V+Y+ GD +P+ +P V I L P KY +N+Y
Sbjct: 2323 WTVPEGQFDHFLVQYK---NGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
Query: 792 --QISEDGEQSLILSTSQTT-----APDAPPDPTVDQVDDT-----SIVVRWSRPQAPIT 839
+S G + T T AP+ P +P + ++ T S+ + W+ PQ
Sbjct: 2380 VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD 2439
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
+ + Y +G + + + VT+ L+PG +Y + +Y + E + PV T
Sbjct: 2440 SFTVQYKDR-DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTA 2498
Query: 900 GTPRSDTVPSPRD----------------LQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
D PSP + L + +++ WT P+ R D
Sbjct: 2499 PQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG-----RFDSFT 2553
Query: 944 VNLPGEHGQRLPI---SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
V G+ + + + V GL PG Y ++ + GR P++A T+ +A
Sbjct: 2554 VQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAE 2613
Query: 1001 TN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
T L + T ++ + WT P Q + L GQP+
Sbjct: 2614 TTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAV 2672
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQ---------------ESPKATGVFTTLQP 1087
V + L+P +Y ++L G Q E+P T + +T P
Sbjct: 2673 RVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTEL-STEAP 2731
Query: 1088 GSSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVV 1140
P E+T T ++ ++WT P F + + G V + + V
Sbjct: 2732 EPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTV 2791
Query: 1141 SGLTPGVEYVYTIQVLRDGQ-----------ERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
GL PG +Y + L +G+ E +A V T P N P G
Sbjct: 2792 GGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPN-----KPRLG 2846
Query: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLS 1238
LTV+ TPD ++ GQ + L + + D + T L
Sbjct: 2847 ELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLE 2901
Query: 1239 PGLEYNVSVYTVKDDKESVPIS---------DTIIPAVP------PPTD-----LRFTNI 1278
P +Y +++Y + PIS +T P P PP + L T
Sbjct: 2902 PDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGS 2961
Query: 1279 GPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1338
PD++ ++W P +F V+Y V + ++ V + L PG +Y + +
Sbjct: 2962 SPDSLSLSWTIPQG-RFDSFTVQYKDRDGRPQVVR--VRGEESEVTVGGLEPGCKYKMHL 3018
Query: 1339 SSVYEQHESTPL--------RGRQKTGLDSPT------------GIDFSDITANSFTVHW 1378
++E P+ + +T PT + +D T +S ++ W
Sbjct: 3019 YGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSW 3078
Query: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1433
+ P + +++ + G+P+ RVP + +T++ L P +Y +++ +G
Sbjct: 3079 MVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVG 3136
Query: 1434 --------REESPLLIGQQSTVSDVPRD-----LEVVAATPTSLLISWDAPAVTVRYYRI 1480
EE+P + + P + L V ++P SL +SW P + +
Sbjct: 3137 PVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 3196
Query: 1481 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYR 1539
Y + G V V G +S T+ GL+PG Y + +Y + G+ P S+ I+
Sbjct: 3197 QYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
Query: 1540 TEID---KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
T + + ++ V V +S+ + W + P + V G P +G D
Sbjct: 3255 TPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ-PQAVPVSG-DLRA 3312
Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPL---VQTAVTTIPAPT--DLKFTQVTPTSLSAQ 1651
+ + GL P +Y ++ P+ +TA T P+P +L T TP S+
Sbjct: 3313 VAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLS 3372
Query: 1652 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
WT P + + V+ K+K G ++ + +A + V V GL + KY +Y L
Sbjct: 3373 WTVPEGEFDSFVVQY--KDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRL 3430
Query: 1712 RPAQGVVTT--LENVSPPRRARVTDATETT--ITISWRTKTETITGFQVDAVPANGQTPI 1767
P TT LE PP +T A ET+ + +SW F V +GQ P
Sbjct: 3431 GPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQ-PR 3489
Query: 1768 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLA---- 1823
+ D R+ T+ L+PG YK LY L R PV TA + + LA
Sbjct: 3490 AVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAP 3549
Query: 1824 ---------------TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868
TTP+S+ +SW + ++++YE P+ ++ ++
Sbjct: 3550 EPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQ--SKI 3607
Query: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP--QLVTLPHPNLHGPEILDVPST 1926
I+GLEP T Y + L ++ PL T P Q P L + DV ++
Sbjct: 3608 LISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTS 3667
Query: 1927 VQKTPFVTHPG 1937
+ + PG
Sbjct: 3668 SLRLNWEAPPG 3678
Score = 278 bits (712), Expect = 3e-74
Identities = 315/1407 (22%), Positives = 546/1407 (38%), Gaps = 174/1407 (12%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T + P+S + W P+ +++++R N G+ K +PGH + TI GL+P
Sbjct: 2634 LTMTDATPDSLSLSWTVPE-GQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDH 2690
Query: 676 VYEGQLISI---QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEIT 732
Y+ L Q+ G V T +P +T E P PL+ +VT +
Sbjct: 2691 KYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEP-PEEPLLGEL-TVTGSS 2748
Query: 733 ASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 2749 PDSLSLSWTIPQGHFDSFTVQYK--DRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYG 2806
Query: 793 ISED---GEQSLILSTSQ---------TTAPDAPPDP-----TVDQVDDTSIVVRWSRPQ 835
+ E G S + T TT P+ P P TV S+ + W P+
Sbjct: 2807 LHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPE 2866
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI- 894
+ + Y +G + +P + VT+S L+P +Y + +Y Q P+ +
Sbjct: 2867 GQFDHFLVQYRNG-DGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVI 2925
Query: 895 ----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVTGYRVDVI 942
+E T P + +P + + ++ VT + WT P+ R D
Sbjct: 2926 GVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG-----RFDSF 2980
Query: 943 PVNLPGEHGQRLPIS-RNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KL 997
V G+ + R +EVT GL PG Y ++ + G+ P++A T K
Sbjct: 2981 TVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKD 3040
Query: 998 DAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP 1039
+A T L + T ++ + W P Q + L GQP
Sbjct: 3041 EAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRNGDGQP 3099
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT-------LQPGSSIP 1092
+ V + L+P +Y ++L G Q + + T +P + P
Sbjct: 3100 KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAP 3159
Query: 1093 -----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVV 1140
P E+T T ++ ++WT P R F + + G V + + V
Sbjct: 3160 EAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTV 3219
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
GL PG +Y + L +GQ + PL P L P G L V+ + T
Sbjct: 3220 GGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTP----LPVEPRLGELAVA---AVT 3272
Query: 1201 PDITGYRITTTPT---------NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
D G T QG V D + L P +Y ++ ++
Sbjct: 3273 SDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQ 3332
Query: 1252 DDKES--VPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS--- 1303
+ K VP+ P P +L T+ PD++ ++W P + +F+V+Y
Sbjct: 3333 NGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEG-EFDSFVVQYKDKD 3391
Query: 1304 ------PVK-NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
PV N+ +V + PS L L G + + +S+ + PL
Sbjct: 3392 GRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISA---DSTTAPLEKELPP 3448
Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
L T ++ T++S + W + + +++ G+PR V + ++T+
Sbjct: 3449 HLGELT---VAEETSSSLRLSWTVAQGPFDSFVVQYRDT--DGQPRAVPVAADQRTVTVE 3503
Query: 1417 NLTPGTEYVVSIVAL-NGREESPL-LIGQQSTVSDVPRD-----------------LEVV 1457
+L PG +Y + L G+ P+ +G + D P L V
Sbjct: 3504 DLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVT 3563
Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
TP S+ +SW + + Y +T G Q V G +S ISGL+P Y
Sbjct: 3564 DTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFL 3621
Query: 1518 VYAV-TGRGDSPASSKPIS----INYRTEIDKP--SQMQVTDVQDNSISVKWLPSSSPVT 1570
+Y + G+ P S++ + +E +P SQ+ VTDV +S+ + W
Sbjct: 3622 LYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFD 3681
Query: 1571 GYRV--------TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+ + T P P + + + L+ Y +++Y ++
Sbjct: 3682 SFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKAD 3741
Query: 1623 PLVQTAVTTIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1679
+ TA T P +P DL+F+++ TS W PP + ++V + P + +
Sbjct: 3742 SIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQ 3800
Query: 1680 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1739
+ + + + GL+ +YEV+V +++ S P G +TT+ + P + R + TE
Sbjct: 3801 VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGF 3858
Query: 1740 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1799
+ W+ + + V V A G P+Q Y + L T+Y + L
Sbjct: 3859 AVLHWKPPQNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGP 3917
Query: 1800 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 1859
+SP I +T ++AP +L TP + L++W P R GY++ + PG +E++
Sbjct: 3918 NLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL- 3976
Query: 1860 RPRPGVTEATITGLEPGTEYTIYVIAL 1886
G+T + GL P T Y + A+
Sbjct: 3977 -LPGGITSHQLLGLFPSTSYNARLQAM 4002
Score = 275 bits (703), Expect = 4e-73
Identities = 321/1498 (21%), Positives = 561/1498 (37%), Gaps = 249/1498 (16%)
Query: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
NS + W P+ ++++++ ++ G+ + + G L ++ GL P Y+ L
Sbjct: 1790 NSVGLSWTVPE-GQFDSFVVQYKDRD--GQPQVVPVEGSLREVSVPGLDPAHRYKLLLYG 1846
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
+ + V + T T T P +V E T+ + +SW+
Sbjct: 1847 LHH--GKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVT 1904
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
F ++Y ++ + Q + + + + L +Y+V +Y S DG+ +
Sbjct: 1905 EGEFDSFEIQY--TDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFS-DGKHVGPV 1961
Query: 804 STSQTTAPD---------APPDP---------TVDQVDDTSIVVRWSRPQAPITGYRIVY 845
T P+ A P+P TV S+ + W+ P+ + + Y
Sbjct: 1962 HVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY 2021
Query: 846 SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-----QQETTG 900
+G + +P VT+S L+P +Y + +Y Q PV + +E T
Sbjct: 2022 RNG-DGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETP 2080
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
+P ++ +P + + ++ VT + WT P+ R D V G+
Sbjct: 2081 SPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQG-----RFDSFTVQYKDRDGR 2135
Query: 953 RLPI---SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPL-----TAQQTTKLDAPT--- 1001
+ + V GL PG Y ++ + GR P+ TA + DAP
Sbjct: 2136 PQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKL 2195
Query: 1002 ---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
+ + T ++ + WT P Q + L GQP+ V + L+P
Sbjct: 2196 RLGQMTVRDITSDSLSLSWTVPEGQFDHF-LVQFKNGDGQPKAVRVPGHEDGVTISGLEP 2254
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFTT-------LQPGSSIPPYN-------------TEV 1098
+Y ++L G Q + V T + P S+ PP T+
Sbjct: 2255 DHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDA 2314
Query: 1099 TETTIVITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
T ++ ++WT P + F + + G V + +SGL P +Y +
Sbjct: 2315 TPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
Query: 1157 RDGQERDAPIVNKVVTPLSP----PTNLHLEA-----NPDTGVLTVSWERSTTPDITGYR 1207
GQ R P+ VT PT +EA P G LTV+ ++PD
Sbjct: 2375 HGGQ-RVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVT---GSSPDSLSLS 2430
Query: 1208 IT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
T T + G V ++S T L PG +Y + +Y + + + P
Sbjct: 2431 WTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGP 2490
Query: 1259 ISDTIIPA-------VPPPTD----------------LRFTNIGPDTMRVTWAPPPSIDL 1295
+S + A P PT+ L T PD++ ++W P
Sbjct: 2491 VSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG-RF 2549
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
+F V+Y + ++ V + L PG +Y + + ++E P+
Sbjct: 2550 DSFTVQYKDRDGRPQAVR--VGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGV 2607
Query: 1356 TGLDSPTG------------------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHF 1397
T ++ T + +D T +S ++ W P + +++ +
Sbjct: 2608 TEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYR--NG 2665
Query: 1398 SGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---------------REESPLLIG 1442
G+P+ RVP + +T++ L P +Y +++ +G EE+P
Sbjct: 2666 DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTE 2725
Query: 1443 QQSTVSDVPRD-----LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVP 1497
+ + P + L V ++P SL +SW P + + Y + G V V
Sbjct: 2726 LSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMR--VR 2783
Query: 1498 GSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYRTEI-----------DKP 1545
G +S T+ GL+PG Y + +Y + GR P S+ ++ + +KP
Sbjct: 2784 GEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKP 2843
Query: 1546 --SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
++ VTD +S+S+ W+ + V +NG G K + +TI GL+
Sbjct: 2844 RLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY--RNGDGQPKVVRVPGHEDGVTISGLE 2901
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTI----PAPTD----------------LKFTQV 1643
P +Y +++Y + P+ VT PAPT+ L T
Sbjct: 2902 PDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGS 2961
Query: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1703
+P SLS WT P + + V+ K++ G + + + + S V V GL KY++ +Y
Sbjct: 2962 SPDSLSLSWTIPQGRFDSFTVQY--KDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLY 3019
Query: 1704 ALKDTLTSRPAQGVVTTLEN-------------VSPPRRAR-----VTDATETTITISWR 1745
L + P V T PP + R VTDAT ++++SW
Sbjct: 3020 GLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWM 3079
Query: 1746 TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1805
F V +GQ R + TI+GL+P YK+ LY + R PV
Sbjct: 3080 VPEGQFDHFLVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPV 3138
Query: 1806 VIDASTAIDAPS------------------NLRFLATTPNSLLVSWQPPRARITGYIIKY 1847
T + PS L ++P+SL +SW P+ R + ++Y
Sbjct: 3139 SAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY 3198
Query: 1848 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1905
+ P+ V R R +E T+ GLEPG +Y +++ L Q+ P+ T LP
Sbjct: 3199 KDRDGQPQVV--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
Score = 268 bits (685), Expect = 5e-71
Identities = 382/1749 (21%), Positives = 660/1749 (37%), Gaps = 299/1749 (17%)
Query: 582 GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
G +Y+ YG +G+ PL Q+ PS P + + T P+S + W
Sbjct: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181
Query: 633 PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
P+ +++++R ++ GR + + G S+ + L P Y L I ++YG
Sbjct: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237
Query: 690 QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
T T+ P PL+ +VT +T S +SW A
Sbjct: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290
Query: 750 FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
F V+Y+ + +PQ + + V +P L P RKY +N+Y + G +S++ T+
Sbjct: 1291 FMVQYK--DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348
Query: 807 Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
T AP++P +P + ++ T S+ + W+ PQ + + Y
Sbjct: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408
Query: 848 SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
+G + + + VT+ L+PG +Y + +Y + E Q PV Q+ET
Sbjct: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
S P +L +VT V + WT PE + ++ Q +P++ +
Sbjct: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524
Query: 961 FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
EVT L P Y ++ + G+ PL+ A + +K L +
Sbjct: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583
Query: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
TD T V + WT P + + + R GQP+ V + + +L+P+ +Y
Sbjct: 1584 TVTDITPDSVGLSWTVPEGEFDSF-VVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642
Query: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
L I+ G + SP + T + +S PP + T+ T ++ ++WT P F
Sbjct: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701
Query: 1116 KLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT- 1172
V + + P+ V S+ V+ L G +Y + + L G++R P+ T
Sbjct: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTTE 1760
Query: 1173 ------------PLSPPTNLHLEANPDT-GVLTVSWERSTTPD--ITGYRITTTPTNGQQ 1217
P P L+ T + +SW T P+ + + +GQ
Sbjct: 1761 ARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSW---TVPEGQFDSFVVQYKDRDGQ- 1816
Query: 1218 GNSLEEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPIS-------------DT 1262
+VV + S + L P Y + +Y + K PIS +T
Sbjct: 1817 ----PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872
Query: 1263 IIPAVPPPT----DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
P P P +L T+ ++W + +F ++Y+ + + + I
Sbjct: 1873 TAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEG-EFDSFEIQYT--DRDGQLQMVRIGG 1929
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR------GRQKTGLDSPTG--------- 1363
N + L+ L Y+V++ + P+ ++ + PT
Sbjct: 1930 DRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPR 1989
Query: 1364 ---IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
+ +D T +S ++ W P + +++ + G+P+ RVP +T++ L P
Sbjct: 1990 LGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEP 2047
Query: 1421 GTEY--------------VVSIVALNGREE------SPLLIGQQSTVSDVPRDLEVVAAT 1460
+Y VS+V + EE P + + + +L V ++
Sbjct: 2048 DHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSS 2107
Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
P SL +SW P + + Y + G Q V G +S T+ GL+PG Y + +Y
Sbjct: 2108 PDSLSLSWTVPQGRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYG 2165
Query: 1521 V-TGRGDSPASSKPISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
+ GR P S+ ++ D P QM V D+ +S+S+ W +
Sbjct: 2166 LHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFL 2225
Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT-- 1631
V KNG G K + +TI GL+P +Y +++Y + P+ +T
Sbjct: 2226 VQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPG 2283
Query: 1632 -----IPAPT--------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
PA T +L T TP SLS WT P Q + V+ K
Sbjct: 2284 KDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGD 2341
Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT------------ 1720
G K + V +SGL KY++++Y P + T
Sbjct: 2342 GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP 2401
Query: 1721 -LENVSPPR-----RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
+E PP VT ++ ++++SW F V +G+ + R + +
Sbjct: 2402 SMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2460
Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---------------IDAP--- 1816
T+ GL+PG YK++LY L++ R PV TA +AP
Sbjct: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
Query: 1817 -----SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
L ++P+SL +SW P+ R + ++Y+ P+ V R ++ T+
Sbjct: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAV--RVGGQESKVTVR 2578
Query: 1872 GLEPGTEYTIYVIALKNNQKSEPLIG-------RKKTDELPQLVTLP--HPNL------- 1915
GLEPG +Y +++ L ++ P+ + T +P + P P L
Sbjct: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638
Query: 1916 HGPEILDVPSTVQKTPFVTH--PGYDTGNG----IQLPG------TSGQQPSVGQQM-IF 1962
P+ L + TV + F H Y G+G +++PG SG +P +M ++
Sbjct: 2639 ATPDSLSLSWTVPEGQF-DHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
Query: 1963 EEHGFRRTTP-PTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAST 2021
HG +R P P P + E P P P L T
Sbjct: 2698 GFHGGQRVGPISVIGVTAAEEETPSPTELSTE-----APEP-------PEEPLLGELTVT 2745
Query: 2022 GQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081
G ++SW Q + + D P RV G + T+ GL G Y +
Sbjct: 2746 GSSP-DSLSLSWTIPQGHFD-SFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMH 2803
Query: 2082 VEALKDQQR 2090
+ L + +R
Sbjct: 2804 LYGLHEGRR 2812
Score = 267 bits (682), Expect = 1e-70
Identities = 338/1555 (21%), Positives = 584/1555 (37%), Gaps = 220/1555 (14%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T S P+S + W PQ + ++++ ++ GR + + G + T++GL+PG
Sbjct: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584
Query: 676 VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Y+ L + + G + V+ T T T+T E P P + ++T+ T
Sbjct: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641
Query: 734 SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
S +SW F V+Y GD +P+ + +P V I L P KY +N+Y
Sbjct: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698
Query: 793 I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
G S+I T+ T AP+ P +P + ++ T S+ + W+
Sbjct: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758
Query: 834 PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
PQ + + Y +G + + + VT+ L+PG +Y + +Y + E + PV
Sbjct: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
Query: 893 ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
Q T TP P +L + T +++ W PE + D
Sbjct: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872
Query: 943 PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
V GQ R+P ++GL P Y ++ G+ P++ T +
Sbjct: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931
Query: 999 ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
APT L + ++ + WT P+ + + + R G+
Sbjct: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990
Query: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
P+ V S+ + L+P +Y VS V + ++ + T T
Sbjct: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050
Query: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
+ P I P E+T T ++ ++W P + F + R G V
Sbjct: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110
Query: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
+ +SGL P +Y + GQ R P+ V + TP PT EA P
Sbjct: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167
Query: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
G LTV+ ++PD T T + G V ++S T L P
Sbjct: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224
Query: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
G +Y + +Y + + + P+S T +P P +L + D++ ++W
Sbjct: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
Query: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
+FLV+Y + + + +S AV ++ L P +Y + + P+
Sbjct: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
Query: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
+T D+ + +D T +S + W P + +++ + GR + V
Sbjct: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399
Query: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
++ +T+ L P +Y + L+GR+ + +T ++P +L V T
Sbjct: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459
Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
+SL +SW + + Y +T G + V + T T+ L+PG Y +Y
Sbjct: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517
Query: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ G D+PA E + + VTD +S+ + W +
Sbjct: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577
Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
P + V NG P G DQ+++ I GL+P+ Y +Y + PL
Sbjct: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635
Query: 1626 -----------QTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------V 1666
QT+ + P + L T VT +SL W P + +R +
Sbjct: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695
Query: 1667 TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-S 1725
P + +E+ + S V+ L T Y +++Y L+ + QG TL V
Sbjct: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755
Query: 1726 PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
PR + ++ ET+ ++W F+V A+G P + R+ + GL P
Sbjct: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIP 3815
Query: 1786 GTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYII 1845
G Y++ + ++ S P+ +T D P+ LR L T ++ W+PP+ + Y +
Sbjct: 3816 GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 3875
Query: 1846 KYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904
+ PG+PP + PG + + L T YT V L+ + P T
Sbjct: 3876 QVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT--- 3929
Query: 1905 PQLVTLPHPNLHGPEILDVPSTVQKTPFVT---------------HPGYDTGNGIQLPG- 1948
L P L+ +T +T H I LPG
Sbjct: 3930 ---------GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGG 3980
Query: 1949 -TS----GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR-PYPPNVGEEIQIG 1997
TS G PS + + PP + + R P+P + GEE+Q G
Sbjct: 3981 ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNG 4035
Score = 262 bits (669), Expect = 3e-69
Identities = 369/1720 (21%), Positives = 630/1720 (36%), Gaps = 307/1720 (17%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T P+S + W P+ ++++++ ++ G+ + + TI L+P
Sbjct: 1583 LTVTDITPDSVGLSWTVPE-GEFDSFVVQYKDRD--GQPQVVPVAADQREVTIPDLEPSR 1639
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Y+ L IQ D S + G+ +P +P VT+ T S
Sbjct: 1640 KYKFLLFGIQ----------DGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDS 1689
Query: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
+SW F V+++ + D PQ + + SV + L GRKY +Y +
Sbjct: 1690 LRLSWTVPEGQFDSFVVQFK---DKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLG 1746
Query: 796 DGEQSLILSTSQTTAPDA--------PPDPTVDQ------VDDTSIVVRWSRPQAPITGY 841
+ + T A A PP P + + V S+ + W+ P+ +
Sbjct: 1747 KKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSF 1806
Query: 842 RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT 901
+ Y +G + + + V++ L P +Y + +Y + + P+ T G
Sbjct: 1807 VVQYKDR-DGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGR 1865
Query: 902 PRSDT--------VPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
++T P P +L E T + + W VT D + G
Sbjct: 1866 EETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWM-----VTEGEFDSFEIQYTDRDG 1920
Query: 952 Q----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----LTAQQTTKLDAPTN 1002
Q R+ RN ++GL Y ++ S G+ P LT + K P
Sbjct: 1921 QLQMVRIGGDRNDIT-LSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPT 1979
Query: 1003 -------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
L + T ++ + WT P Q + L GQP+ V
Sbjct: 1980 ATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAVRVPGHEE 2038
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL---------QPGSSIP-----PYN 1095
+ L+P +Y ++L G Q + V T +P P P
Sbjct: 2039 GVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLL 2098
Query: 1096 TEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
E+T T ++ ++WT P R F + + G V + + V GL PG +
Sbjct: 2099 GELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRK 2158
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG--Y 1206
Y + L +G+ R P+ VT E +PD + + + T DIT
Sbjct: 2159 YKMHLYGLHEGR-RVGPVSAVGVTAPE-------EESPDAPLAKLRLGQMTVRDITSDSL 2210
Query: 1207 RITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
++ T GQ + L + + D + T L P +Y +++Y +
Sbjct: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2270
Query: 1256 SVPIS----------DTIIPA-VPPPT----------DLRFTNIGPDTMRVTWAPPPSID 1294
P+S + + PA PPT +L T+ PD++ ++W P
Sbjct: 2271 VGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEG-Q 2329
Query: 1295 LTNFLVRYSPVKNEEDVAELSISPS-DNAVVLTNLLPGTEYV--------------VSVS 1339
+FLV+Y KN + + + P ++ V ++ L P +Y VS
Sbjct: 2330 FDHFLVQY---KNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAI 2386
Query: 1340 SVYEQHESTPLRGRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITGYRIRHH 1393
V E TP P + + + +S ++ W P+ + +++
Sbjct: 2387 GVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYK 2446
Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL----LIGQQSTVS 1448
GRP+ RV + +T+ L PG +Y + + L+ GR P+ + Q V
Sbjct: 2447 DR--DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVD 2504
Query: 1449 DVPR------------------DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
+ P +L V ++P SL +SW P + + Y + G
Sbjct: 2505 ETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRP- 2563
Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYRTEID------ 1543
Q V G +S T+ GL+PG Y + +Y + GR P S+ ++ +
Sbjct: 2564 -QAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMT 2622
Query: 1544 -----KP--SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
KP ++ +TD +S+S+ W + V +NG G K +
Sbjct: 2623 PEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEDG 2680
Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI----PAPTDLK------------- 1639
+TI GL+P +Y +++Y + P+ VT P+PT+L
Sbjct: 2681 VTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLG 2740
Query: 1640 ---FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1696
T +P SLS WT P + V+ K++ G + + + + S V V GL
Sbjct: 2741 ELTVTGSSPDSLSLSWTIPQGHFDSFTVQY--KDRDGRPQVMRVRGEESEVTVGGLEPGR 2798
Query: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVS-----------PPRRAR-----VTDATETTI 1740
KY++ +Y L + P V T + PP + R VTDAT ++
Sbjct: 2799 KYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSL 2858
Query: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
++SW F V +GQ + R + TI+GL+P YK+ LY +
Sbjct: 2859 SLSWMVPEGQFDHFLVQYRNGDGQPKVVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2917
Query: 1801 RSSPVVIDASTAID----APSN----------------LRFLATTPNSLLVSWQPPRARI 1840
R P+ + TA + AP+ L ++P+SL +SW P+ R
Sbjct: 2918 RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRF 2977
Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG--- 1897
+ ++Y+ P+ V R R +E T+ GLEPG +Y +++ L Q+ P+
Sbjct: 2978 DSFTVQYKDRDGRPQVV--RVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGV 3035
Query: 1898 ------RKKTDELPQLVTLP--HPNLHGPEILDVPSTVQKTPFVTHPG--------YDTG 1941
+ T +P + P P L + D ++ G Y G
Sbjct: 3036 TAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG 3095
Query: 1942 NG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTPPTTATPIRHRPRPYPPNV 1990
+G +++PG SG +P +M ++ HG +R P +A + P P
Sbjct: 3096 DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR-VGPVSAIGVTEEETPSPTEP 3154
Query: 1991 GEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVG 2050
E P P L TG ++SW Q + +
Sbjct: 3155 STEAPEA------------PEEPLLGELTVTGSSP-DSLSLSWTVPQGRFD-SFTVQYKD 3200
Query: 2051 TDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090
D +P RV G + T+ GL G Y + + L + QR
Sbjct: 3201 RDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR 3240
Score = 243 bits (621), Expect = 1e-63
Identities = 353/1584 (22%), Positives = 602/1584 (38%), Gaps = 267/1584 (16%)
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
V W + DT + F++ + E G LP +P PG Y ++++ + G
Sbjct: 979 VVWTAQPDTFAYFQLRMRVPE-GPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGG 1037
Query: 798 EQSLIL-----------STSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
+ S + +++ P + TV S+++RW+ P+ + I Y
Sbjct: 1038 KPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK 1097
Query: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
+G + + S ++ L PG +Y +Y + P+V + + P+SD
Sbjct: 1098 DR-DGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKIL--PQSDP 1154
Query: 907 VP-SPRDLQFVEVTDV---KVTIMWTPPESAVTGYRV-----DVIPVNLPGEHGQRLPIS 957
P +P L + VTD + + WT PE + V D P +P E +R +
Sbjct: 1155 SPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFV- 1213
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT---KLDAPTNLQFVNE------ 1008
V+ L P Y F +F +++ + PLTA TT + + P +F+ +
Sbjct: 1214 ------VSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGEL 1267
Query: 1009 -----TDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
T ++ + WT + + + +GQP+ V ++ + L P +Y
Sbjct: 1268 TVTGVTPDSLRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGDENEVTVPGLDPDRKYK 1326
Query: 1064 VSLVAIKGNQ------------------ESPKATGVFTTLQPGSSIPPYNTEVTET---- 1101
++L ++G Q E+P T + T P S P E+T T
Sbjct: 1327 MNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEA-PESPEEPLLGELTVTGSSP 1385
Query: 1102 -TIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
++ + WT F + + G V + V GL PG +Y + L +
Sbjct: 1386 DSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHE 1445
Query: 1159 GQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
GQ R P+ VT P T LE P G LTV+ TP+ G ++ T
Sbjct: 1446 GQ-RVGPVSAVGVTAPQQEETPPATESPLE--PRLGELTVT---DVTPNSVG--LSWTVP 1497
Query: 1214 NGQ-----------QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
GQ G V ADQ T NL P +Y +++Y + D + P+S
Sbjct: 1498 EGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVV 1557
Query: 1263 IIPAVPPPT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
I+ A PP +L T+I PD++ ++W P + +F+V+Y
Sbjct: 1558 IVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDG 1616
Query: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG- 1363
+ V + ++ V + +L P +Y + + + +P+ KT G SP
Sbjct: 1617 QPQV--VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAP 1674
Query: 1364 -----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
+ +D T +S + W P + ++ + P+ V S+T+T L
Sbjct: 1675 PRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKD---GPQVVPVEGHERSVTVTPL 1731
Query: 1419 TPGTEYVVSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTS 1463
G +Y + L G++ L +S + D PR +L+V T S
Sbjct: 1732 DAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNS 1791
Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT- 1522
+ +SW P + + Y + G V V GS ++ GL P Y + +Y +
Sbjct: 1792 VGLSWTVPEGQFDSFVVQYKDRDGQPQV--VPVEGSLREVSVPGLDPAHRYKLLLYGLHH 1849
Query: 1523 GRGDSPASSKPISINYR---TEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVT 1570
G+ P S+ I+ TE P+ ++ V + +++ + W+ +
Sbjct: 1850 GKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD 1909
Query: 1571 GYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630
+ + T ++G + G D+ ++T+ GL+ Y+V++Y + P+ A+T
Sbjct: 1910 SFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALT 1967
Query: 1631 T------------IPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
P P +L T TP SLS WT P Q + V+ +
Sbjct: 1968 VPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGD 2025
Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP----- 1726
G K + + V +SGL KY++++Y P V VT E +P
Sbjct: 2026 GQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEP 2085
Query: 1727 ----PRRAR--------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
P A VT ++ ++++SW F V +G+ + R + +
Sbjct: 2086 SMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2144
Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLA 1823
T+ GL+PG YK++LY L++ R PV TA DAP +
Sbjct: 2145 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRD 2204
Query: 1824 TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIY 1882
T +SL +SW P + ++++++ P+ V VP GV TI+GLEP +Y +
Sbjct: 2205 ITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMN 2261
Query: 1883 VIALKNNQKSEP-----LIGRKKTDELPQLVTLP-------HPNLH-------GPEILDV 1923
+ Q+ P L K +E+ T P P L P+ L +
Sbjct: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSL 2321
Query: 1924 PSTVQKTPFVTH--PGYDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRT 1970
TV + F H Y G+G ++PG SG +P +M ++ HG +R
Sbjct: 2322 SWTVPEGQF-DHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR- 2379
Query: 1971 TPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTT 2030
P +A + P ++ P E P L TG +
Sbjct: 2380 VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEE----------PLLGELTVTGSSP-DSLS 2428
Query: 2031 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090
+SW Q + + D P RV G + T+ GL G Y + + L + +R
Sbjct: 2429 LSWTVPQGRFD-SFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRR 2487
Query: 2091 HKVREEVVTVGNSVNEGLNQPTDD 2114
VG G+ P +D
Sbjct: 2488 ---------VGPVSTVGVTAPQED 2502
Score = 242 bits (617), Expect = 4e-63
Identities = 361/1676 (21%), Positives = 626/1676 (37%), Gaps = 278/1676 (16%)
Query: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+W P P + Y +++ P A +P ++Y +GL PG Y
Sbjct: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEY---------- 816
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
+VT TS P + T P V +T ++ + W+ V
Sbjct: 817 ---QVTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
F V Y G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 868 DRFVVSY--VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
Query: 796 DGEQSL-ILSTSQTTAPDAPPD------PTVDQ------------VDDTS-IVVRWSRPQ 835
G L +L T+ P P P + Q D+T + V W+
Sbjct: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
Query: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE-NQESTPVV 893
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
Query: 894 IQ----QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPV 944
Q ++ +S P +L + T + + WT PE + + D P
Sbjct: 1045 YQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ 1104
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTKLD 998
+P E QR A +T L PG Y F ++ + PL A Q
Sbjct: 1105 VVPVEGPQR-------SAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
Query: 999 APT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
P NL + T ++ + WT P Q + + R G+P+ V + + +
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY-RDRDGRPQVVPVEGPERSFVVSS 1216
Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTETT 1102
L P +Y +L I + T TT PP T VT +
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
Query: 1103 IVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
+ ++WT A P F + + +QG V D + V GL P +Y + LR G+
Sbjct: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR-GR 1335
Query: 1161 ERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDITGY 1206
+R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1336 QRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSLSL 1390
Query: 1207 RIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1391 FWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
Query: 1258 PISDTIIPA-----VPPPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
P+S + A PP T +L T++ P+++ ++W P +F+V+Y
Sbjct: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQYK 1509
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL------------- 1350
+ V + ++ V + NL P +Y +++ +++ PL
Sbjct: 1510 DKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAP 1567
Query: 1351 -RGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
K L+ G + +DIT +S + W P + +++ G+P+ V
Sbjct: 1568 ATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVAA 1625
Query: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV------SDVPR--DLEVVAA 1459
+ +T+ +L P +Y + + +G+ SP+ + ++ PR +L V
Sbjct: 1626 DQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685
Query: 1460 TPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1519
TP SL +SW P + + + + G Q V G + + T++ L G Y +Y
Sbjct: 1686 TPDSLRLSWTVPEGQFDSFVVQFKDKDG---PQVVPVEGHERSVTVTPLDAGRKYRFLLY 1742
Query: 1520 AVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSSSP 1568
+ G+ + + R+ +D KP ++QVT V NS+ + W
Sbjct: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802
Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------------ 1616
+ V ++G P G E+++ GL P Y + +Y +
Sbjct: 1803 FDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860
Query: 1617 -PSGESQPLVQTAVTTIPAPT----DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK 1671
+G + +T T PAP +L + T +L W + + ++ T ++
Sbjct: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT--DR 1918
Query: 1672 TGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD----------TLT----SRPAQGV 1717
G ++ + + D + + +SGL +Y V++Y D LT +P++
Sbjct: 1919 DGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPP 1978
Query: 1718 VTTLENVSPPR--RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV 1775
T E PR VTDAT ++++SW F V +GQ R +
Sbjct: 1979 TATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVR-VPGHE 2037
Query: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA------------IDAP------- 1816
TI+GL+P YK+ LY + R PV + TA ++AP
Sbjct: 2038 EGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPL 2097
Query: 1817 -SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1875
L ++P+SL +SW P+ R + ++Y+ P+ V R +E T+ GLEP
Sbjct: 2098 LGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQ--VVRVGGEESEVTVGGLEP 2155
Query: 1876 GTEYTIYVIALKNNQKSEPL--IGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 1933
G +Y +++ L ++ P+ +G +E L L + D+ S +
Sbjct: 2156 GRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWT 2215
Query: 1934 THPG--------YDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTPPT 1974
G + G+G +++PG SG +P +M ++ HG +R P +
Sbjct: 2216 VPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVS 2275
Query: 1975 TATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWA 2034
P EE+ + + P L +T ++LS +SW
Sbjct: 2276 AVGLT-------APGKDEEMAPASTEPPTPEPPIKPRLEELTVTDAT-PDSLS---LSWT 2324
Query: 2035 PFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090
+ ++ + + G D +P RVPG T++GL Y + + QR
Sbjct: 2325 VPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
Score = 240 bits (612), Expect = 1e-62
Identities = 309/1457 (21%), Positives = 559/1457 (38%), Gaps = 211/1457 (14%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
Query: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Y+ L YG E R +T + P T T P PL+
Sbjct: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Query: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
Query: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Query: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
Query: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
Query: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
Query: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
T+ +A T L + T ++ + W P Q + L
Sbjct: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
Query: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA--VPPPTD----------------LRFT 1276
L P +Y +++Y + P+S + P PT+ L T
Sbjct: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
PD++ ++W P +F V+Y + V + ++ V + L PG +Y +
Sbjct: 3174 GSSPDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKM 3230
Query: 1337 SVSSVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGY 1388
+ ++E P+ T L +P ++ + +T++S + W + +
Sbjct: 3231 HLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSF 3290
Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV 1447
+++ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 3291 LVQYRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAP 3348
Query: 1448 SDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
P +L V ATP S+ +SW P + + Y + G +Q V ++
Sbjct: 3349 DTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREV 3406
Query: 1504 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
T+ GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ +
Sbjct: 3407 TVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLS 3466
Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV------------ 1609
W + P + V ++ G + DQ +T+E L+P +Y
Sbjct: 3467 WTVAQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRL 3524
Query: 1610 --VSVYAQNPSGESQPLVQTAVTTIPAPTD-----LKFTQVTPTSLSAQWTPPNVQLTGY 1662
VS E P + A P + L T TP S+ W+ +
Sbjct: 3525 GPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSF 3584
Query: 1663 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT-- 1720
V+ ++ G + + + D S +++SGL +T Y +Y L + P TT
Sbjct: 3585 VVQY--EDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL 3642
Query: 1721 -----LENVSPPRRAR--VTDATETTITISWRTKTETITGFQVD-AVPA------NGQTP 1766
S PR ++ VTD T +++ ++W F + VP+ + +
Sbjct: 3643 APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPL 3702
Query: 1767 IQRTIK-PDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST---AIDAPSNLRF 1821
+QR + P R S + L+ GT Y + LY L ++ + A T +++P +L+F
Sbjct: 3703 LQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQF 3762
Query: 1822 LATTPNSLLVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATITGLEPGTEYT 1880
S V+W PP +R + + Y+ G P+ V + + + GL PG Y
Sbjct: 3763 SEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK--LQGLIPGARYE 3820
Query: 1881 IYVIALKNNQKSEPLIG 1897
+ V++++ ++SEPL G
Sbjct: 3821 VTVVSVRGFEESEPLTG 3837
Score = 227 bits (578), Expect = 1e-58
Identities = 301/1392 (21%), Positives = 522/1392 (37%), Gaps = 195/1392 (14%)
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
Query: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
Query: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
A+ G+ T P T+ + ++
Sbjct: 919 PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978
Query: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
+ WT P F+L +R +G A EV D +V PG Y ++ + G +
Sbjct: 979 VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
PI+ + + P G LTV+ S T P+ +
Sbjct: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPA 1266
+ G V Q S +L PG +Y +Y K P+ P
Sbjct: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
Query: 1267 VPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
PP +L T+ PD++ ++W P F+V+Y V + + + + V+
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVV 1214
Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITA 1371
++L P +Y ++ + + PL T L+ P + + +T
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
+S + W + + +++ + G+P+ V N +T+ L P +Y +++ L
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGL 1332
Query: 1432 NGREE--------------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISW 1468
GR+ SP +G ++ S + +L V ++P SL + W
Sbjct: 1333 RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFW 1392
Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDS 1527
P + + + Y + G + V G +S T+ GL+PG Y + +Y + G+
Sbjct: 1393 TVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
Query: 1528 PASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
P S+ ++ + E + ++ VTDV NS+ + W + V
Sbjct: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT--IPAPT 1636
K+ G + DQ E+T+ L+P +Y +++Y + PL VT PAP
Sbjct: 1511 KD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPA 1568
Query: 1637 -------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
+L T +TP S+ WT P + + V+ K++ G + + +A D
Sbjct: 1569 TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQVVPVAAD 1626
Query: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN-----VSPPRRAR--VTDAT 1736
V + L + KY+ ++ ++D P T+ +PPR VTD T
Sbjct: 1627 QREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPT 1686
Query: 1737 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
++ +SW F V +G P ++ RS T+T L G Y+ LY L
Sbjct: 1687 PDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744
Query: 1797 NDNARSSPVVIDAST----AID-----------APSNLRFLATTPNSLLVSWQPPRARIT 1841
R P+ D +T A+D L+ T NS+ +SW P +
Sbjct: 1745 LGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFD 1804
Query: 1842 GYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL----- 1895
++++Y ++ G P +VVP + E ++ GL+P Y + + L + ++ P+
Sbjct: 1805 SFVVQYKDRDGQP--QVVP-VEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAI 1861
Query: 1896 -IGRKKTDELPQLVTLPHPNLHGPEIL---DVPSTVQKTPFVTHPGYDTGNGIQLPGTSG 1951
GR++T+ T P P H E+ T+ + VT +D+ IQ G
Sbjct: 1862 TAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFE-IQYTDRDG 1920
Query: 1952 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPH 2011
Q QM+ T + R+ Y + G+ + H+ V P
Sbjct: 1921 Q-----LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPS 1975
Query: 2012 GPGLNPNAS--------TGQEALSQTT-----ISWAPFQDTSEYIISCHPVGTDEEPLQF 2058
P P A+ G+ ++ T +SW + ++ + + G D +P
Sbjct: 1976 EP---PTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAV 2031
Query: 2059 RVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG-NSVNEGLNQPTDDSCF 2117
RVPG T++GL Y + + QR V VG + E PT+ S
Sbjct: 2032 RVPGHEEGVTISGLEPDHKYKMNLYGFHGGQR---MGPVSVVGVTAAEEETPSPTEPSME 2088
Query: 2118 DPYTVSHYAVGD 2129
P +G+
Sbjct: 2089 APEPAEEPLLGE 2100
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 281 bits (720), Expect = 4e-75
Identities = 251/942 (26%), Positives = 403/942 (42%), Gaps = 54/942 (5%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+
Sbjct: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847
VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P
Sbjct: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345
Query: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR
Sbjct: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963
P+DL+ +VT + + W P V Y ++ P E + + + R+ T
Sbjct: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022
+ L Y V AV ES P+TAQ+TT+ + APTNL+ T W +
Sbjct: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516
Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075
++ YR+T + + + NL P + Y VS+ AI ++ S
Sbjct: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128
+ + TT P S P N +V T ++ + W PA R+ +++ +PS +G E
Sbjct: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
+ S+V+ L P Y T+ L E PL+ NL + +P T
Sbjct: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS-- 1246
L V W+ + + Y++ P G G + + + NL P Y V+
Sbjct: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750
Query: 1247 -VYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
VYT D + T++ + +++ N P+++ V W P P + + V YSPV
Sbjct: 751 PVYTEGDGGRTSDTGRTLMRGL--ARNVQVYNPTPNSLDVRWDPAPG-PVLQYRVVYSPV 807
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGI 1364
+ + + V L L+P T Y V++ ++Y E P + +T P +
Sbjct: 808 DGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNL 867
Query: 1365 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
T NS +V W + YRI + P VP RN++ L L P T Y
Sbjct: 868 RVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPY 927
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
++++A+ + L G TV + P+++ + T +SWD V Y+I Y
Sbjct: 928 KITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK 987
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
G N P++ F G ++ T+ L P Y + VYA G S P++ T
Sbjct: 988 PVGSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLTDQGTTLYL 1041
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
+ ++ + ++ VKW P + T YR+ +P +G + G +T GL
Sbjct: 1042 NVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SETSHCFTGLS 1099
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP 1645
P +Y V+V+ Q P+ E P V T PT+ TP
Sbjct: 1100 PDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 1140
Score = 281 bits (719), Expect = 5e-75
Identities = 240/929 (25%), Positives = 404/929 (43%), Gaps = 39/929 (4%)
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L
Sbjct: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280
Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
+P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G
Sbjct: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ L +P + E R G V ++ L P EY T+Q + + V +V
Sbjct: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PL P +L L + + V WE P I T + +E V ++
Sbjct: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW
Sbjct: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512
Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES
Sbjct: 513 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570
Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
L G ++T P + + T+NS TV W + YRI + P G
Sbjct: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
+ + +NS+ L L P T Y +++ +L E + G+ T + R+L V
Sbjct: 631 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV
Sbjct: 691 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749
Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
V GD +S R +QV + NS+ V+W P+ PV YRV +P
Sbjct: 750 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637
+G P+++ + + +E L P Y V++ A GE P Q P +
Sbjct: 807 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866
Query: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696
L+ T SLS W + + YR+ +P P+ E P ++V++ L T
Sbjct: 867 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 925
Query: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
Y+++V A+ + G T+ + PP+ ++D T +SW + G+++
Sbjct: 926 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 984
Query: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816
P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T
Sbjct: 985 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043
Query: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876
++L+ ++ V W P RA T Y +K P R R T TGL P
Sbjct: 1044 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 1101
Query: 1877 TEYTIYVIALKNNQKSEPLIGRKKTDELP 1905
T+Y + V N + + ++ T P
Sbjct: 1102 TDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130
Score = 262 bits (670), Expect = 3e-69
Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%)
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+AP + + + S V W+ P + Y++ Y P G E + S L DL+
Sbjct: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P
Sbjct: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334
Query: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
A TGY + PV P E RL + N ++T L P Y V AV H S
Sbjct: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390
Query: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
+P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V
Sbjct: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
S + L++L + YTVS+ A+ ESP T TT + TEVT
Sbjct: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
TW + + G + + T D ++V L P Y +I +
Sbjct: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569
Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
G ER PI+ P S P NL + N + LTV W+ + + YRIT P+
Sbjct: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
G +GN + Q+S L P Y ++V ++ D E ++ + +
Sbjct: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685
Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
LR + T+ V W + + + Y+P + + I + N +L NL P T
Sbjct: 686 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
Y V+V VY + + +T + + + T NS V W + YR+
Sbjct: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803
Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
+ P + VP + + L L P T Y V++VAL + E +P ++
Sbjct: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863
Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+
Sbjct: 864 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
P Y ITV AV GD ++ N RT + P + ++D V W PS SP
Sbjct: 923 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978
Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL
Sbjct: 979 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036
Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
T TDLK Q+ + +W+P T YR++++P + T +EI + +S
Sbjct: 1037 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 1094
Query: 1689 VSGLMVATKYEVSVY 1703
+GL T Y V+V+
Sbjct: 1095 FTGLSPDTDYGVTVF 1109
Score = 245 bits (626), Expect = 3e-64
Identities = 246/941 (26%), Positives = 389/941 (41%), Gaps = 67/941 (7%)
Query: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
+ N V P L P+NL + VSW + + Y++ P +G G E
Sbjct: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
V ++S +L P EY V+VY+V +D+ S P+ T P L ++GP TM
Sbjct: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
V W P T +++ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V
Sbjct: 327 HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384
Query: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399
S P+ R+ T L P + D+T ++ V W + Y +R+ PE
Sbjct: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
+E V S S +L +L T Y VS+ A++ ESP + Q++T P +L++
Sbjct: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501
Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
T +WD A V YRIT+ G +S E + G ++T L P Y +++
Sbjct: 502 VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560
Query: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
A+ + D S + + I T+ K P +QV + NS++VKW P+S V Y
Sbjct: 561 TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-T 1631
R+T P G G +T T G Q + ++ L+P Y ++V + P GE + T
Sbjct: 620 RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679
Query: 1632 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1691
+ +L+ + ++L+ +W Y++ P GP + + + +++ ++
Sbjct: 680 LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRN 738
Query: 1692 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1751
L T Y V+V + TL R +V + T ++ + W +
Sbjct: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPV 797
Query: 1752 TGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810
++V P +G P + + P + R + L P T Y + L L + +P
Sbjct: 798 LQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857
Query: 1811 T-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVT 1866
T P NLR T NSL V+W + Y I Y P + VP R V
Sbjct: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV- 916
Query: 1867 EATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPST 1926
+ L+P T Y I VIA+ + L G +T L LP N+H I D T
Sbjct: 917 --ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGL-----LPPQNIH---ISDEWYT 966
Query: 1927 VQKTPFVTHPGYDTGNGIQLPGTSGQQPS---VGQQMIFEEHGFRRTTPPTTATPIRHRP 1983
+ + P G I +P VG+ + H P TT
Sbjct: 967 RFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNL---NPSTT-------- 1015
Query: 1984 RPYPPNVGEEIQIG-HIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEY 2042
Y NV + G +P D LY + L T Q + W+P + + Y
Sbjct: 1016 --YDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL----KTYQIGWDTFCVKWSPHRAATSY 1069
Query: 2043 IISCHPV-GTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2082
+ P GT + + R G+ TS TGL+ Y + V
Sbjct: 1070 RLKLSPADGTRGQEITVR--GSETSHCFTGLSPDTDYGVTV 1108
Score = 200 bits (508), Expect = 2e-50
Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)
Query: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
P + +QW QP + YIL ++P R KE + +N + L P Y
Sbjct: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
+++Q H TS PVT VT PL + + ++T S+ V
Sbjct: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420
Query: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE
Sbjct: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478
Query: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
+ + T AP + + +V W + ++ YRI ++P E L
Sbjct: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538
Query: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
N++ +L P Y ++I A+ ++ + +I E TT P+S PR+
Sbjct: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594
Query: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
LQ T +T+ W P V YR+ P G R + L P
Sbjct: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654
Query: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L
Sbjct: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
G + + + LRNLQP + YTV++V + + + + TL G
Sbjct: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774
Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
++ YN T ++ + W PAP + V S P + T S SIVV G
Sbjct: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827
Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P Y V + + DG+ +P + + P S P NL + T L+V+W+ +
Sbjct: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885
Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
P + YRI +PT G+ ++E V +++ L P Y ++V V +D +
Sbjct: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941
Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
++ + + PP ++ ++ RV+W P PS + + + Y PV + E + +
Sbjct: 942 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998
Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
+ L NL P T Y V+V + Y+ S PL + T + T + I ++F V
Sbjct: 999 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058
Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
W +P T YR++ P R +E V S S T L+P T+Y V++ E
Sbjct: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116
Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
P + + + +TV P + TP
Sbjct: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140
Score = 155 bits (391), Expect = 6e-37
Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S +S Y + W P S + E + G N+ + L P +YE +SI E
Sbjct: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D + + P+ TT + V T++S V W AS V +R+ Y+
Sbjct: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624
Query: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
S Q + SV + L P Y + V + DGE + +T +
Sbjct: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684
Query: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
+ V +++ VRW + Y++ Y+P+ G + +P N L +LQP
Sbjct: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744
Query: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
Y +T+ V + T+ T R+ R++Q T + + W P V
Sbjct: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
YRV PV+ + + + NT + L P Y + A+ E P AQ +
Sbjct: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857
Query: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
T P NL+ ET +++ V W + YR+ T +Y P +
Sbjct: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W
Sbjct: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974
Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+P+P +G+K+ +P E + S + L P Y + D P+
Sbjct: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 1033
Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
++ T T+L + DT V W S T YR+ +P +G +G E V
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 1087
Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
++S F LSP +Y V+V+ +VK+ P P PPP
Sbjct: 1088 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 224 bits (572), Expect = 6e-58
Identities = 227/838 (27%), Positives = 361/838 (43%), Gaps = 63/838 (7%)
Query: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN-----LPGEHGQRLPI 956
P D+ +PRDL E + + + WT VTGY+V P+ LP E +
Sbjct: 227 PPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVP 286
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLV 1015
+ T + GL P Y V A+ + ++ +TT L+ P L N T ++LV
Sbjct: 287 AGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQNTTAHSLLV 345
Query: 1016 RW-TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE 1074
W + P A TGYR+T + G +Q +GP LR+L+P ++Y V++ + G
Sbjct: 346 AWRSVPGA--TGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSV 403
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVT- 1132
P AT + + T+I+++W P G++L R G E P++V
Sbjct: 404 GP-ATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVL 462
Query: 1133 -SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP---IVNKVVTPLSPPTNLHLEANPDT 1188
SD + GL PG EY T+ L +G E P + P+SP T+L P
Sbjct: 463 PSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQ 522
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
V VSW S P T YRI T G + V+ Q++ D++ GL Y V V
Sbjct: 523 RV-RVSW--SPVPGATQYRIIVRSTQGVERTL---VLPGSQTAFDLDDVQAGLSYTVRVS 576
Query: 1249 TVKDDKESVPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
+E T+ P LR +RV W P P + F + +S
Sbjct: 577 ARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGFRISWSTG 634
Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1364
E + ++ P A +T L PGT Y V+VS + + E +T P +
Sbjct: 635 SGPE--SSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTV 692
Query: 1365 DFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
+ +++S T+ W P AT GYR+ H H G + V L L P TE
Sbjct: 693 HVTQASSSSVTITWTRVPGAT--GYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTE 748
Query: 1424 YVVSIVA----LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1479
Y V + A ++G S ++ V V R L+++ A+ L I+W YR
Sbjct: 749 YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSR-LQILNASSDVLRITW-VGVTGATAYR 806
Query: 1480 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
+ +G + G P++ +PG+ +A I GL+ GV Y++ V A+ G + P+SI
Sbjct: 807 LAWGRSEGG-PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT----PVSIVVT 861
Query: 1540 TEIDKP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
T + P + V ++S+ ++W P G+ + P+ G +++ GP+ +
Sbjct: 862 TPPEAPPALGTLHVVQRGEHSLRLRWEPVPR-AQGFLLHWQPEGGQ--EQSRVLGPELSS 918
Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTDLKFTQVTPTSLSAQWTP 1654
++GL+P +Y V + P+GE TA T P +L+ + S++ WTP
Sbjct: 919 YHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTP 978
Query: 1655 PNVQLTGYRVRVTPKEKTGPMKEINLAPD-----SSSVVVSGLMVATKYEVSVYALKD 1707
+ + + Y + P GP +E+ +P SSS V+GL Y S+ + D
Sbjct: 979 VS-RASSYILSWRPLR--GPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLD 1033
Score = 213 bits (541), Expect = 2e-54
Identities = 225/847 (26%), Positives = 360/847 (42%), Gaps = 66/847 (7%)
Query: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLT-VGLTRRGQP-----RQ 1041
P+T AP +L + ++ V+WT +TGY++ LT GQP ++
Sbjct: 223 PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282
Query: 1042 YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVF-TTLQPGSSIPPYNTEVTE 1100
NV + LR L+P +EY V+++A+ N +G TT G + NT T
Sbjct: 283 VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNT--TA 340
Query: 1101 TTIVITWTPAP-RIGFKLGVRPSQGGEAPR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
++++ W P G+++ R GG + E+ GS+++ L PG +Y T+ L
Sbjct: 341 HSLLVAWRSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF- 399
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQG 1218
G+ T S L T +L +SW + P+ GYR+ G +
Sbjct: 400 GRSVGPATSLMARTDASVEQTLRPVILGPTSIL-LSW--NLVPEARGYRLEWRRETGLEP 456
Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP-----PPTDL 1273
+ V+ +D + D L PG EY +++YT+ + E V T++P P P TDL
Sbjct: 457 PQ-KVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHE-VATPATVVPTGPELPVSPVTDL 514
Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGT 1332
+ T + +RV+W+P P +VR + + V + P S A L ++ G
Sbjct: 515 QATELPGQRVRVSWSPVPGATQYRIIVR-----STQGVERTLVLPGSQTAFDLDDVQAGL 569
Query: 1333 EYVVSVSSVYEQHESTP----LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY 1388
Y V VS+ E + +R +T L P G+ A V W P +G+
Sbjct: 570 SYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATRVRVAW-GPVPGASGF 627
Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP--LLIGQQST 1446
RI SG +P + +T L PGT Y V++ L GREE P +++ +
Sbjct: 628 RISWSTG--SGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDP 685
Query: 1447 VSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
+ V R + V A+ +S+ I+W P T YR+++ G P + V G + A +
Sbjct: 686 LGPV-RTVHVTQASSSSVTITWTRVPGATG--YRVSWHSAHG--PEKSQLVSGEATVAEL 740
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE---IDKPSQMQVTDVQDNSISVKW 1562
GL+P +YT+ V A D P P S+ RT + + S++Q+ + + + + W
Sbjct: 741 DGLEPDTEYTVHVRAHVAGVDGP----PASVVVRTAPEPVGRVSRLQILNASSDVLRITW 796
Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+ + T YR+ G GP + + + I GL+ V Y V V A E
Sbjct: 797 VGVTG-ATAYRLAWGRSEG-GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT 854
Query: 1623 PL---VQTAVTTIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEI 1678
P+ V T PA L Q SL +W P P Q G+ + P+ G +
Sbjct: 855 PVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEG--GQEQSR 910
Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
L P+ SS + GL AT+Y V + L A+ T P RV D +
Sbjct: 911 VLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSID 970
Query: 1739 TITISWRTKTETITGFQVDAVPANG---QTPIQRTIKPDV-RSYTITGLQPGTDYKIYLY 1794
++T++W T + + + P G + P P + S +TGL+PG Y L
Sbjct: 971 SVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLT 1029
Query: 1795 TLNDNAR 1801
+ D R
Sbjct: 1030 PVLDGVR 1036
Score = 198 bits (503), Expect = 6e-50
Identities = 212/811 (26%), Positives = 342/811 (42%), Gaps = 54/811 (6%)
Query: 1096 TEVTETTIVITWTPA--PRIGFKLGVRPSQGGEAP-----REVTSDSG--SIVVSGLTPG 1146
+E + ++ + WT A P G+K+ P G P +EV +G S+ + GL P
Sbjct: 241 SEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPL 300
Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY 1206
EY T+ L +A T L P L ++ N L V+W + P TGY
Sbjct: 301 TEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQ-NTTAHSLLVAWR--SVPGATGY 356
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA 1266
R+T +G G + ++ + Q S +L PG +Y V+V T+ S
Sbjct: 357 RVTWRVLSG--GPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTD 414
Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
LR +GP ++ ++W P + + + + E ++ + L
Sbjct: 415 ASVEQTLRPVILGPTSILLSWNLVP--EARGYRLEWRRETGLEPPQKVVLPSDVTRYQLD 472
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITANSFTVHWIAPR 1382
L PGTEY +++ ++ E HE TG + P T + +++ V W +P
Sbjct: 473 GLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSW-SPV 531
Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPL 1439
T YRI G R +P S+ + L ++ G Y V + A G E S L
Sbjct: 532 PGATQYRIIVRSTQ--GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVL 589
Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
+ ++ L VV + T + ++W P +RI++ G+ P T+P
Sbjct: 590 TVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWST--GSGPESSQTLPPD 646
Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSI 1558
+ I+GL+PG Y + V + GR + PA+ I RT+ P + + VT +S+
Sbjct: 647 STATDITGLQPGTTYQVAVSVLRGREEGPAAV----IVARTDPLGPVRTVHVTQASSSSV 702
Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
++ W TGYRV+ + GP K++ + T ++GL+P EY V V A + +
Sbjct: 703 TITWTRVPG-ATGYRVSW--HSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRA-HVA 758
Query: 1619 GESQPLVQTAVTTIPAPTD----LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
G P V T P P L+ + L W T YR+ + + GP
Sbjct: 759 GVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVT-GATAYRL-AWGRSEGGP 816
Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA-RVT 1733
M+ L ++ S + GL Y V V AL P VVTT P V
Sbjct: 817 MRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVV 876
Query: 1734 DATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
E ++ + W GF + P GQ R + P++ SY + GL+P T Y++ L
Sbjct: 877 QRGEHSLRLRWEPVPRA-QGFLLHWQPEGGQEQ-SRVLGPELSSYHLDGLEPATQYRVRL 934
Query: 1794 YTLNDNARSSPVVIDAST-AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPG 1851
L + A T + PS LR + T+ +S+ ++W P +R + YI+ +
Sbjct: 935 SVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPV-SRASSYILSWRPLR 993
Query: 1852 SPPREV--VPRPRPGVTEA-TITGLEPGTEY 1879
P +EV P+ PG++ + +TGLEPG Y
Sbjct: 994 GPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024
Score = 197 bits (501), Expect = 1e-49
Identities = 208/847 (24%), Positives = 349/847 (41%), Gaps = 69/847 (8%)
Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDV 1311
VP++ + P DL + ++RV W S +T + V+Y+P+ +
Sbjct: 222 VPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSER 280
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
E+++ + +V L L P TEY V+V ++Y + G +T + + TA
Sbjct: 281 QEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTA 340
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
+S V W + TGYR+ SG P ++ + + S+ L +L PGT+Y V++
Sbjct: 341 HSLLVAWRSVPGA-TGYRVTWRV--LSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVST 397
Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
L GR P T + V + L V PTS+L+SW+ R YR+ + G P
Sbjct: 398 LFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNL-VPEARGYRLEWRRETGLEP 456
Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQV 1550
Q+ +P + + GL+PG +Y +T+Y + + + + + + +Q
Sbjct: 457 PQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQA 516
Query: 1551 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
T++ + V W P T YR+ ++ G +T QT ++ +Q + Y V
Sbjct: 517 TELPGQRVRVSWSPVPG-ATQYRIIV--RSTQGVERTLVLPGSQTAFDLDDVQAGLSYTV 573
Query: 1611 SVYAQNPSGESQPLVQTA---VTTIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRV 1666
V A+ E V T T A L+ T + W P P +G+ R+
Sbjct: 574 RVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGF--RI 629
Query: 1667 TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
+ +GP L PDS++ ++GL T Y+V+V L+ PA +V + + P
Sbjct: 630 SWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGR-EEGPAAVIVARTDPLGP 688
Query: 1727 PRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
R VT A+ +++TI+W T+ TG++V A+G Q + + + GL+P
Sbjct: 689 VRTVHVTQASSSSVTITW-TRVPGATGYRVSWHSAHGPEKSQ-LVSGEATVAELDGLEPD 746
Query: 1787 TDYKIYL---YTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGY 1843
T+Y +++ D +S VV A + S L+ L + + L ++W
Sbjct: 747 TEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYR 806
Query: 1844 IIKYEKPGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1902
+ G P R + PG T+ A I GLE G Y++ V AL +++ P
Sbjct: 807 LAWGRSEGGPMRHQI---LPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTP-------- 855
Query: 1903 ELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSG----QQPSVGQ 1958
+ +VT P P L VQ+ ++ +P G QP GQ
Sbjct: 856 -VSIVVTTPP---EAPPALGTLHVVQRGEHSLRLRWE-----PVPRAQGFLLHWQPEGGQ 906
Query: 1959 Q---MIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHL-YPHGPG 2014
+ ++ E AT R R P G P +V P P
Sbjct: 907 EQSRVLGPELSSYHLDGLEPATQYRVRLSVLGP-------AGEGPSAEVTARTESPRVPS 959
Query: 2015 LNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV---GTDEEPLQFRVPGTSTSATLTG 2071
+ ++ T++W P S YI+S P+ G + +PG S+S +TG
Sbjct: 960 I--ELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTG 1017
Query: 2072 LTRGATY 2078
L G +Y
Sbjct: 1018 LEPGVSY 1024
Score = 194 bits (494), Expect = 6e-49
Identities = 220/875 (25%), Positives = 369/875 (42%), Gaps = 72/875 (8%)
Query: 696 DFTTTSTSTPVTSN----TVTGETTPFSPLVATSES----VTEITASSFVVSWVSASDTV 747
DF+ T P+ S T G P +TS ++E ++ S V W +AS V
Sbjct: 200 DFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPV 259
Query: 748 SGFRVEYE-LSEEGD----EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
+G++V+Y L+ G E Q +++P+ TSV + L P +Y V V + + +
Sbjct: 260 TGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAV 319
Query: 803 LSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA 862
T++TTA + P + T+ S++V W R TGYR+ + G + + L
Sbjct: 320 SGTARTTALEGP-ELTIQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQ 377
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
SV L DL+PG Y +T+ + + T + P V +
Sbjct: 378 GSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-------VILGPTS 430
Query: 923 VTIMWTPPESAVTGYRVDVI-PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVS 981
+ + W A GYR++ L LP S T ++ GL PG Y ++ +
Sbjct: 431 ILLSWNLVPEA-RGYRLEWRRETGLEPPQKVVLP-SDVTRYQLDGLQPGTEYRLTLYTLL 488
Query: 982 HGRE-SKPLTAQQT---TKLDAPTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR 1036
G E + P T T + T+LQ V V W+P P A T YR+ V T+
Sbjct: 489 EGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGA--TQYRIIVRSTQ- 545
Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS--SIPPY 1094
G R + S + + L ++Q YTV + A G +E A+ + +P + ++P
Sbjct: 546 GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRREPETPLAVPGL 604
Query: 1095 NTEVTETTIV-ITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
V++ T V + W P P GF++ G E+ + + DS + ++GL PG Y
Sbjct: 605 RVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVA 664
Query: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
+ VLR +E A ++ PL P +H+ + V T++W R P TGYR++
Sbjct: 665 VSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV-TITWTR--VPGATGYRVSWHS 721
Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP-- 1270
+G + + L V + + D L P EY V V + P S ++ P P
Sbjct: 722 AHGPEKSQL---VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPAS-VVVRTAPEPVG 777
Query: 1271 --TDLRFTNIGPDTMRVTWAPPPSIDLTNFLV-RYSPVKNEEDVAELSISPSD-NAVVLT 1326
+ L+ N D +R+TW + +T R + ++E I P + ++ +
Sbjct: 778 RVSRLQILNASSDVLRITW-----VGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIR 832
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT---ANSFTVHWIAPRA 1383
L G Y V V+++ E TP+ T ++P + + +S + W P
Sbjct: 833 GLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRW-EPVP 891
Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
G+ + PE G+ + + +S L L P T+Y V + L E P +
Sbjct: 892 RAQGFLLHWQPE--GGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGP--SAE 947
Query: 1444 QSTVSDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGE---TGGNSPVQEFTV 1496
+ ++ PR +L VV + S+ ++W P Y +++ G P T+
Sbjct: 948 VTARTESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTL 1006
Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
PG S+ ++GL+PGV Y ++ V P +S
Sbjct: 1007 PGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEAS 1041
Score = 180 bits (457), Expect = 1e-44
Identities = 220/885 (24%), Positives = 367/885 (41%), Gaps = 86/885 (9%)
Query: 607 SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGR-----WKEATIPG 661
S+S P ++ ++E SQ S +QW A ++ Y +++ P +G+ +E +P
Sbjct: 231 STSAPRDLVLSEPSSQ--SLRVQWTAAS-GPVTGYKVQYTPLTGLGQPLPSERQEVNVPA 287
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
S ++GL+P Y+ +I++ E TT+ P
Sbjct: 288 GETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP---------------- 331
Query: 722 VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
++ TA S +V+W S +G+RV + + G Q +L SV + DL
Sbjct: 332 ---ELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVL-SGGPTQQQELGPGQGSVLLRDLE 386
Query: 782 PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV--DDTSIVVRWSR-PQAPI 838
PG Y V V + +S+ +TS DA + T+ V TSI++ W+ P+A
Sbjct: 387 PGTDYEVTVSTLF---GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEA-- 441
Query: 839 TGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE-STPVVIQQ 896
GYR+ + ++ LP L LQPG +Y +T+Y + E E +TP +
Sbjct: 442 RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVP 501
Query: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
P S DLQ E+ +V + W+P A T YR+ ++ E LP
Sbjct: 502 TGPELPVSPVT----DLQATELPGQRVRVSWSPVPGA-TQYRI-IVRSTQGVERTLVLPG 555
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----PLTAQQTTKLDAPTNLQFVNETDST 1012
S+ F ++ + G++Y +V A RE + + T L P L+ V +
Sbjct: 556 SQTAF-DLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATR 613
Query: 1013 VLVRWTP-PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
V V W P P A +G+R++ T G + P + + LQP + Y V++ ++G
Sbjct: 614 VRVAWGPVPGA--SGFRISWS-TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLGVRPSQGGEAPRE 1130
+E P A V T G + T+ + +++ ITWT P G+++ + G E +
Sbjct: 671 REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP----IVNKVVTPLSPPTNLHLEANP 1186
V+ ++ + GL P E YT+ V D P +V P+ + L + N
Sbjct: 731 VSGEATVAELDGLEPDTE--YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQI-LNA 787
Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246
+ VL ++W T T YR+ + G G +++ + S L G+ Y+V
Sbjct: 788 SSDVLRITWVGVT--GATAYRLAWGRSEG--GPMRHQILPGNTDSAEIRGLEGGVSYSVR 843
Query: 1247 VYTVKDDKESVPISDTII--PAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
V + D+E P+S + P PP L G ++R+ W P P FL+ +
Sbjct: 844 VTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQ 901
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG 1363
P +E L P ++ L L P T+Y V +S + E +T
Sbjct: 902 PEGGQEQSRVL--GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPS 959
Query: 1364 IDFS--DITANSFTVHWIAPRATITGYRIRHHP-----EHFSGRPREDRVPHSRNSITLT 1416
I+ D + +S T+ W P + + Y + P + G P+ +P +S +T
Sbjct: 960 IELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQ--TLPGISSSQRVT 1016
Query: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1461
L PG Y+ S+ + P Q+ V PR L V P
Sbjct: 1017 GLEPGVSYIFSLTPVLDGVRGPEASVTQTPV--CPRGLADVVFLP 1059
Score = 172 bits (436), Expect = 3e-42
Identities = 205/820 (25%), Positives = 342/820 (41%), Gaps = 52/820 (6%)
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL--- 1221
P+ S P +L L + P + L V W ++ P +TGY++ TP G G L
Sbjct: 223 PVTRPPDDSTSAPRDLVL-SEPSSQSLRVQWTAASGP-VTGYKVQYTPLTGL-GQPLPSE 279
Query: 1222 --EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIG 1279
E V A ++S L P EY V+V + + +S T +L N
Sbjct: 280 RQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTT 339
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
++ V W P T + V + V + + + P +V+L +L PGT+Y V+VS
Sbjct: 340 AHSLLVAWRSVPGA--TGYRVTWR-VLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVS 396
Query: 1340 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW-IAPRATITGYRIRHHPEHFS 1398
+++ + +T + + S + W + P A GYR+ E
Sbjct: 397 TLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGL 454
Query: 1399 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGRE-ESPLLI---GQQSTVSDVPRD 1453
P++ +P L L PGTEY +++ L G E +P + G + VS V D
Sbjct: 455 EPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVT-D 513
Query: 1454 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
L+ + +SW +P YRI T G + +PGS++ + ++ G+
Sbjct: 514 LQATELPGQRVRVSW-SPVPGATQYRIIVRSTQGVE--RTLVLPGSQTAFDLDDVQAGLS 570
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
YT+ V A G + AS + T + P ++V + V W P +G+R
Sbjct: 571 YTVRVSARVGPREGSASVLTVRREPETPLAVPG-LRVVVSDATRVRVAWGPVPG-ASGFR 628
Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP 1633
++ + G GP ++T PD T I GLQP Y V+V E V A T
Sbjct: 629 ISWS--TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPL 686
Query: 1634 APT-DLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1691
P + TQ + +S++ WT P TGYRV + GP K ++ +++ + G
Sbjct: 687 GPVRTVHVTQASSSSVTITWTRVPGA--TGYRV--SWHSAHGPEKSQLVSGEATVAELDG 742
Query: 1692 LMVATKYEVSVYALKDTLTSRPAQGVVTTL-ENVSPPRRARVTDATETTITISWRTKTET 1750
L T+Y V V A + PA VV T E V R ++ +A+ + I+W T
Sbjct: 743 LEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGA 802
Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810
T +++ + G + + + S I GL+ G Y + + L + +PV I +
Sbjct: 803 -TAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVT 861
Query: 1811 TAIDAP---SNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVT 1866
T +AP L + +SL + W+P PRA+ G+++ ++ G + V P ++
Sbjct: 862 TPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEGGQEQSRVLGPE--LS 917
Query: 1867 EATITGLEPGTEYTI--YVIALKNNQKSEPLIGRKKTDELPQL------VTLPHPNLHGP 1918
+ GLEP T+Y + V+ S + R ++ +P + ++ L
Sbjct: 918 SYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWT 977
Query: 1919 EILDVPSTVQKTPFVTHPGYDT-GNGIQLPGTSGQQPSVG 1957
+ S + + PG + G+ LPG S Q G
Sbjct: 978 PVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTG 1017
Score = 159 bits (402), Expect = 3e-38
Identities = 181/720 (25%), Positives = 287/720 (39%), Gaps = 66/720 (9%)
Query: 562 QDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPS 621
+D E GT Y++ S +GR +G +T S VE +
Sbjct: 383 RDLEPGTDYEVTVST------------LFGRSVGPATSLMARTDAS----VEQTLRPVIL 426
Query: 622 QPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
P S + WN + Y L WR + + ++ +P + Y + GL+PG Y L
Sbjct: 427 GPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTL 484
Query: 682 ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
++ + GH+ +TP T TG P SP+ T TE+ VSW
Sbjct: 485 YTLLE-GHE-----------VATPATV-VPTGPELPVSPV--TDLQATELPGQRVRVSW- 528
Query: 742 SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQ 799
S + +R+ S +G E + L LP + T+ ++ D+ G Y V V +G
Sbjct: 529 SPVPGATQYRIIVR-STQGVE-RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586
Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
S++ + P A P V D T + V W P +G+RI +S G + LP
Sbjct: 587 SVLTVRREPETPLAVPGLRVVVSDATRVRVAWG-PVPGASGFRISWSTG-SGPESSQTLP 644
Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVT 919
+ + ++ LQPG Y + + + +E VI R+D + R + + +
Sbjct: 645 PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVI------VARTDPLGPVRTVHVTQAS 698
Query: 920 DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
VTI WT A TGYRV + G +L T AE+ GL P Y V A
Sbjct: 699 SSSVTITWTRVPGA-TGYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTEYTVHVRA 755
Query: 980 VSHGRESKPLTAQQTT---KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRR 1036
G + P + T + + LQ +N + + + W T YRL G +
Sbjct: 756 HVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG-ATAYRLAWGRSEG 814
Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
G R + + +R L+ Y+V + A+ G++E + V TT P + P T
Sbjct: 815 GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTT--PPEAPPALGT 872
Query: 1097 ----EVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
+ E ++ + W P PR GF L +P G E R + + S + GL P +Y
Sbjct: 873 LHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRV 932
Query: 1152 TIQVLRD-GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
+ VL G+ A + + +P P L + DT + +V+ + + Y ++
Sbjct: 933 RLSVLGPAGEGPSAEVTARTESPRVPSIELRV---VDTSIDSVTLAWTPVSRASSYILSW 989
Query: 1211 TPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP 1268
P GQ+ + + SS L PG+ Y S+ V D S T P P
Sbjct: 990 RPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCP 1049
Score = 124 bits (311), Expect = 1e-27
Identities = 150/584 (25%), Positives = 237/584 (40%), Gaps = 59/584 (10%)
Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1580
V+ R + A P++ P + +++ S+ V+W +S PVTGY+V TP
Sbjct: 211 VSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLT 270
Query: 1581 G-----PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAP 1635
G P + +T + + GL+P EY V+V A + + + TA TT
Sbjct: 271 GLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEG 330
Query: 1636 TDLKFTQVTPTSLSAQW-TPPNVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGL 1692
+L T SL W + P TGYRV RV GP ++ L P SV++ L
Sbjct: 331 PELTIQNTTAHSLLVAWRSVPGA--TGYRVTWRVL---SGGPTQQQELGPGQGSVLLRDL 385
Query: 1693 MVATKYEVSVYALKDTLTSRPAQGVVTTL---ENVSPPRRARVTDATETTITISWRTKTE 1749
T YEV+V TL R + G T+L + S + R T+I +SW E
Sbjct: 386 EPGTDYEVTV----STLFGR-SVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPE 440
Query: 1750 TITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808
G++++ G P Q+ + P DV Y + GLQPGT+Y++ LYTL + +
Sbjct: 441 A-RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATV 499
Query: 1809 ASTAIDAP----SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864
T + P ++L+ + VSW P II G V+P +
Sbjct: 500 VPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQ-- 557
Query: 1865 VTEATITGLEPGTEYTIYVIA-LKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDV 1923
T + ++ G YT+ V A + + S ++ ++ E P V G ++
Sbjct: 558 -TAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-------GLRVVVS 609
Query: 1924 PSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRP 1983
+T + + PG +G ++ ++G P Q + P +TAT I
Sbjct: 610 DATRVRVAWGPVPG---ASGFRISWSTGSGPESSQTL----------PPDSTATDITGLQ 656
Query: 1984 RPYPPNVGEEIQIGHI--PREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSE 2041
V + G P + P GP + + Q + S TI+W +
Sbjct: 657 PGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVT--QASSSSVTITWTRVPGATG 714
Query: 2042 YIISCHPV-GTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEA 2084
Y +S H G ++ L V G +T A L GL Y + V A
Sbjct: 715 YRVSWHSAHGPEKSQL---VSGEATVAELDGLEPDTEYTVHVRA 755
Score = 119 bits (299), Expect = 3e-26
Identities = 127/480 (26%), Positives = 205/480 (42%), Gaps = 43/480 (8%)
Query: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP-----MKE 1677
P+ + + AP DL ++ + SL QWT + +TGY+V+ TP G +E
Sbjct: 223 PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282
Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATE 1737
+N+ +SV + GL T+Y+V+V AL G T P + + T
Sbjct: 283 VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP--ELTIQNTTA 340
Query: 1738 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
++ ++WR+ TG++V +G Q+ + P S + L+PGTDY++ + TL
Sbjct: 341 HSLLVAWRS-VPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF 399
Query: 1798 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS--PP 1854
+ + A T LR + P S+L+SW P AR GY +++ + PP
Sbjct: 400 GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGLEPP 457
Query: 1855 REVVPRPRPGVTEATITGLEPGTEY--TIYVIALKNNQKSEPLIGRKKTDELPQLVTLPH 1912
++VV VT + GL+PGTEY T+Y + L+ ++ + P ELP P
Sbjct: 458 QKVVLPS--DVTRYQLDGLQPGTEYRLTLYTL-LEGHEVATPATVVPTGPELP---VSPV 511
Query: 1913 PNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV---GQQMIFEEHGFRR 1969
+L E+ V +P PG T I + T G + ++ G Q F+ +
Sbjct: 512 TDLQATELPGQRVRVSWSPV---PGA-TQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQA 567
Query: 1970 TTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQT 2029
T R PR +V + RE P P P ++
Sbjct: 568 GLSYTVRVSARVGPREGSASVLT------VRRE-------PETPLAVPGLRVVVSDATRV 614
Query: 2030 TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2089
++W P S + IS G+ E Q +P ST+ +TGL G TY + V L+ ++
Sbjct: 615 RVAWGPVPGASGFRISWS-TGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 201 bits (510), Expect = 9e-51
Identities = 184/688 (26%), Positives = 292/688 (42%), Gaps = 53/688 (7%)
Query: 795 EDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
E+ ++ + S T P P + +V S +V W+ + YR+VY P+ G
Sbjct: 339 EEQDREIKASAHAITGP--PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPD 396
Query: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
E+ + T +S L +L +Y I ++A+ + S + GT + +P DL
Sbjct: 397 EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTAS------EGLRGTETTLALPMASDLL 450
Query: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPV--NLPGEHGQRLPISRNTFAEVTGLSPGVT 972
+VT+ + + W A +GY + P+ L G+ + +T E++GL P
Sbjct: 451 LYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTE 509
Query: 973 YYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V+A+ S P+T Q+TT L P NL+ N ++ + W P QI GYR+
Sbjct: 510 YTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVY 569
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
+ + V P ++ +PL+ L P +EYT+++ +I +S TGVFTT + +
Sbjct: 570 NNADGTEINEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQ 628
Query: 1092 PPYNTEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVE 1148
EVT + +TW P A KL P GG+ V + S V+ GL PG E
Sbjct: 629 YLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTE 688
Query: 1149 Y-VYTIQVLRDGQERDAPIV---------NKVVTPLSPPTNLH----------LEANPDT 1188
Y V + VL DG E + + T + P T++ + + T
Sbjct: 689 YEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETT 748
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV-----VHADQSSCTFDNLSPGLEY 1243
L V W+ S + D+ +R+T QG+ EEV V Q++ L P EY
Sbjct: 749 SSLRVKWDISDS-DVQQFRVTYMTA---QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804
Query: 1244 NVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
V+V + D E V +S +P+ P +LR + + +R+TW PPS + + +
Sbjct: 805 KVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITW-DPPSSPVKGYRIV 862
Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP 1361
Y PV E + N +++TNLL G +Y V + + S L G KT
Sbjct: 863 YKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGV 922
Query: 1362 TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR-EDRVPHSRNSITLTNLTP 1420
T + + S HW R T YR+ E R + E V L P
Sbjct: 923 TNLQAKHVEMTSLCAHWQVHRHA-TAYRV--VIESLQDRQKQESTVGGGTTRHCFYGLQP 979
Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVS 1448
+EY +S+ E P + + T S
Sbjct: 980 DSEYKISVYTKLQEIEGPSVSIMEKTQS 1007
Score = 194 bits (493), Expect = 8e-49
Identities = 175/642 (27%), Positives = 289/642 (45%), Gaps = 49/642 (7%)
Query: 1096 TEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPREVTSDS--GSIVVSGLTPGVEYVY 1151
+EVT + ++ WT AP K V P++GG+ P EV D S V+ L EY
Sbjct: 362 SEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGK-PDEVVVDGTVSSTVLKNLMSLTEYQI 420
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
+ + + + L ++L L + + V W+ P +GY I
Sbjct: 421 AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENS-MRVKWD--AVPGASGYLILYA 477
Query: 1212 P-TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVP 1268
P T G G+ E + + L P EY V+VY + ++ S P++ +T + A+
Sbjct: 478 PLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL-ALS 536
Query: 1269 PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
PP +LR +N+G ++ R+TW P S + + + Y+ E + E+ + P L L
Sbjct: 537 PPRNLRISNVGSNSARLTW-DPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGL 593
Query: 1329 LPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRATITG 1387
P TEY +++ S+Y++ +S PL G T + + ++ ++T +SF V W A
Sbjct: 594 TPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGL 653
Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA-LNGREESPLLIGQQST 1446
+++ P + G+ E + ++S + L PGTEY VS++A L+ ES ++ +T
Sbjct: 654 HKLMWIPV-YGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTT 712
Query: 1447 VSD---------VP------------RDLEVVAATPTSLLISWDAPAVTVRYYRITYGET 1485
+ VP R+L V T +SL + WD V+ +R+TY
Sbjct: 713 LDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTA 772
Query: 1486 GGNSPVQEFT----VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 1541
G+ P +E VPGS++ + L P +Y +TV + G+ + S P
Sbjct: 773 QGD-PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAP---GKTLP 828
Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
P ++V++ N + + W P SSPV GYR+ P + PGPT G D + I
Sbjct: 829 SSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITN 888
Query: 1602 LQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTG 1661
L ++Y V ++A SG S L T T+L+ V TSL A W + T
Sbjct: 889 LLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHW-QVHRHATA 947
Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1703
YRV V + +E + ++ GL ++Y++SVY
Sbjct: 948 YRV-VIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVY 988
Score = 187 bits (474), Expect = 1e-46
Identities = 230/987 (23%), Positives = 403/987 (40%), Gaps = 125/987 (12%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P L++ ++ + I W P GY++ V P + G+ Q + T A + G
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTATKAIIQG 88
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQ----------------------QTTKLDAPTNLQ 1004
L P Y ++ A + +ESKP Q ++ +P ++
Sbjct: 89 LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVK 148
Query: 1005 FVNET----DSTVLV--RWTPPRAQ-----------ITGYRLTVGLTRRGQPRQYNVGPS 1047
FV +T D +LV W+ R +T + + TR G QY+ P
Sbjct: 149 FVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLA-QYSGDPR 207
Query: 1048 VSKY------------PLRNLQPASEYTVSLVAIK---GNQESPKA---TGV------FT 1083
+ + +RNL T++ +A+ N P+A TGV T
Sbjct: 208 IEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILIT 267
Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGL 1143
+ I P + + E+ + + F +GV+ + E +E+ S+ S V +
Sbjct: 268 DGKSQDDIIPPSRNLRESGVEL---------FAIGVKNADVNEL-QEIASEPDSTHVYNV 317
Query: 1144 TPGVEYVYTI------QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWER 1197
+ ++T+ + +E+D I PPT L + + V+W
Sbjct: 318 AE-FDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL-ITSEVTARSFMVNWTH 375
Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
+ ++ YR+ PT G G E VV SS NL EY ++V+ + S
Sbjct: 376 APG-NVEKYRVVYYPTRG--GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASE 432
Query: 1258 PISDTIIP-AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN--EEDVAEL 1314
+ T A+P +DL ++ ++MRV W P + +L+ Y+P+ D E+
Sbjct: 433 GLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEM 490
Query: 1315 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
I + + L+ LLP TEY V+V +++ + S P+ G++ T L P + S++ +NS
Sbjct: 491 KIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNS 550
Query: 1374 FTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
+ W I GYRI ++ + G + + L LTP TEY ++I ++
Sbjct: 551 ARLTWDPTSRQINGYRIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYD 608
Query: 1434 REESPLLIGQQSTVSDVPRD--LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+S L G +T +VP LE+ T S ++W + +++ + G
Sbjct: 609 EGQSEPLTGVFTT-EEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGK-T 666
Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-------------DSPASSKPISINY 1538
+E + + + I GL+PG +Y +++ AV G DS + +I
Sbjct: 667 EEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVP 726
Query: 1539 RTEIDKPSQ-----MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK---TKTA 1590
T + Q + V D +S+ VKW S S V +RVT G + T
Sbjct: 727 TTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMV 786
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA--PTDLKFTQVTPTSL 1648
Q + ++ L P EY V+V GE V T+P+ P +L+ ++ L
Sbjct: 787 PGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVS-VSAPGKTLPSSGPQNLRVSEEWYNRL 845
Query: 1649 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
W PP+ + GYR+ P GP E + D ++++++ L+ Y V ++A + +
Sbjct: 846 RITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQAS 905
Query: 1709 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
S G+V TL +A+ + T++ W+ T ++V + +
Sbjct: 906 GFSDALTGMVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHA-TAYRVVIESLQDRQKQE 962
Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYT 1795
T+ + GLQP ++YKI +YT
Sbjct: 963 STVGGGTTRHCFYGLQPDSEYKISVYT 989
Score = 186 bits (472), Expect = 2e-46
Identities = 181/672 (26%), Positives = 281/672 (41%), Gaps = 52/672 (7%)
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPA 1059
PT L T + +V WT + YR+ TR G+P + V +VS L+NL
Sbjct: 356 PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSL 415
Query: 1060 SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLG 1118
+EY +++ AI + S G TTL + +VTE ++ + W P G+ +
Sbjct: 416 TEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLIL 475
Query: 1119 VRP----SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT-P 1173
P G E ++ I +SGL P EY T+ + G+E P+ + T
Sbjct: 476 YAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAM-FGEEASDPVTGQETTLA 534
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
LSPP NL + +N + ++W+ T+ I GYRI N G + EV ++
Sbjct: 535 LSPPRNLRI-SNVGSNSARLTWD-PTSRQINGYRIV---YNNADGTEINEVEVDPITTFP 589
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTWAPPPS 1292
L+P EY ++++++ D+ +S P++ VP L + D+ RVTW P S
Sbjct: 590 LKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTW-HPLS 648
Query: 1293 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
D + + PV + E+ + ++ V+ L PGTEY VS+ +V + + +
Sbjct: 649 ADEGLHKLMWIPVYGGK-TEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVT 707
Query: 1353 RQKTGLDS-------------------PTGID---FSDITANSFTVHWIAPRATITGYRI 1390
T LDS TGI D T +S V W + + +R+
Sbjct: 708 AVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRV 767
Query: 1391 RHHPEHFSGRPRED-----RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
+ G P E+ VP S+N++ L L P TEY V++ + E +
Sbjct: 768 TYMTA--QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGK 825
Query: 1446 TV-SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
T+ S P++L V L I+WD P+ V+ YRI Y P E V +T
Sbjct: 826 TLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTIL 885
Query: 1505 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP 1564
I+ L G+DY + ++A G S A + + +T + +Q V+ S+ W
Sbjct: 886 ITNLLSGMDYNVKIFASQASGFSDALTGMV----KTLFLGVTNLQAKHVEMTSLCAHW-Q 940
Query: 1565 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1624
T YRV + T G T GLQP EY +SVY + E P
Sbjct: 941 VHRHATAYRVVIESLQ-DRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEG-PS 998
Query: 1625 VQTAVTTIPAPT 1636
V T PT
Sbjct: 999 VSIMEKTQSLPT 1010
Score = 182 bits (462), Expect = 3e-45
Identities = 178/724 (24%), Positives = 311/724 (42%), Gaps = 51/724 (7%)
Query: 1219 NSLEEVVHADQSS-----CTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
N L+E+ S+ FD + +E + +++ I + PPT+L
Sbjct: 300 NELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL 359
Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
+ + + V W P ++ + V Y P + + E+ + + ++ VL NL+ TE
Sbjct: 360 ITSEVTARSFMVNWTHAPG-NVEKYRVVYYPTRGGKP-DEVVVDGTVSSTVLKNLMSLTE 417
Query: 1334 YVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1392
Y ++V ++Y S LRG + T L + + D+T NS V W A +GY I +
Sbjct: 418 YQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SGYLILY 476
Query: 1393 HP--EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-D 1449
P E +G +E ++ + I L+ L P TEY V++ A+ G E S + GQ++T++
Sbjct: 477 APLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALS 536
Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
PR+L + S ++WD + + YRI Y G + E V +T + GL
Sbjct: 537 PPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGLT 594
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ--MQVTDVQDNSISVKWLPSSS 1567
P +YTI ++++ G S +P++ + TE + P+Q +++ +V +S V W P S+
Sbjct: 595 PLTEYTIAIFSIYDEGQS----EPLTGVFTTE-EVPAQQYLEIDEVTTDSFRVTWHPLSA 649
Query: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
+++ P G G T+ +Q IEGL+P EY VS+ A G +V
Sbjct: 650 DEGLHKLMWIPVYG-GKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTA 708
Query: 1628 AVTTI------PAPTDLKFTQVTP----------------TSLSAQWTPPNVQLTGYRVR 1665
TT+ PA T + T VT +SL +W + + +RV
Sbjct: 709 VGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVT 768
Query: 1666 VTPKEKTGPMKEIN--LAPDS-SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1722
+ + I + P S +++++ L+ T+Y+V+V + TL
Sbjct: 769 YMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLP 828
Query: 1723 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT-IKPDVRSYTIT 1781
+ S P+ RV++ + I+W + + G+++ P + P T + D+ + IT
Sbjct: 829 S-SGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILIT 887
Query: 1782 GLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARIT 1841
L G DY + ++ + S + T +NL+ SL WQ R T
Sbjct: 888 NLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HAT 946
Query: 1842 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1901
Y + E ++ G T GL+P +EY I V + + +KT
Sbjct: 947 AYRVVIESLQDRQKQ-ESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIMEKT 1005
Query: 1902 DELP 1905
LP
Sbjct: 1006 QSLP 1009
Score = 160 bits (404), Expect = 2e-38
Identities = 156/663 (23%), Positives = 281/663 (42%), Gaps = 54/663 (8%)
Query: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIV 788
+E+TA SF+V+W A V +RV Y G +P + + T +S + +L+ +Y +
Sbjct: 362 SEVTARSFMVNWTHAPGNVEKYRVVY-YPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQI 420
Query: 789 NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPS 848
V+ I + T T A D + V + S+ V+W +GY I+Y+P
Sbjct: 421 AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPL 479
Query: 849 VE---GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSD 905
E G E+ + ET + LS L P +Y +T+YA+ + S PV Q+ T
Sbjct: 480 TEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL------ 533
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVT 965
+ PR+L+ V + W P + GYR ++ N G + + T +
Sbjct: 534 ALSPPRNLRISNVGSNSARLTWDPTSRQINGYR--IVYNNADGTEINEVEVDPITTFPLK 591
Query: 966 GLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL+P Y +F++ +S+PLT TT ++ A L+ T + V W P A
Sbjct: 592 GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFT 1083
++L G+ + + + + L+P +EY VSL+A+ ES T V T
Sbjct: 652 GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711
Query: 1084 TL-----QPGSSIPPYNT---------------EVTETTIVITW--TPAPRIGFKLGVRP 1121
TL +P ++I P + + T +++ + W + + F++
Sbjct: 712 TLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMT 771
Query: 1122 SQGGEAPRE-------VTSDSGSIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTP 1173
+QG P E V ++++ L P EY T+ + DG+ K + P
Sbjct: 772 AQGD--PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTL-P 828
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
S P NL + + L ++W+ ++P + GYRI P + G +LE V AD ++
Sbjct: 829 SSGPQNLRV-SEEWYNRLRITWDPPSSP-VKGYRIVYKPVS-VPGPTLETFVGADINTIL 885
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
NL G++YNV ++ + S ++ + T+L+ ++ ++ W
Sbjct: 886 ITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHA 945
Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
++ + ++ E ++ L P +EY +SV + ++ E +
Sbjct: 946 TAYRVVIESLQDRQKQ---ESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002
Query: 1354 QKT 1356
+KT
Sbjct: 1003 EKT 1005
Score = 100 bits (248), Expect = 2e-20
Identities = 130/581 (22%), Positives = 232/581 (39%), Gaps = 53/581 (9%)
Query: 624 NSHPIQWNAPQPSHISKYILRWRP--KNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
NS ++W+A + S Y++ + P + G KE I + GL P Y
Sbjct: 457 NSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT--- 511
Query: 682 ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
VT + S PVT T +P L ++ + ++S ++W
Sbjct: 512 ----------VTVYAMFGEEASDPVTGQETTLALSPPRNL-----RISNVGSNSARLTWD 556
Query: 742 SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSL 801
S ++G+R+ Y + +G E +++ T+ + L P +Y + ++ I ++G+
Sbjct: 557 PTSRQINGYRIVYN-NADGTEINEVEV-DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEP 614
Query: 802 ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
+ T A +D+V S V W A +++++ P G + E+ L E
Sbjct: 615 LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-----GTPRSDTVPSP------ 910
+S + L+PG +Y +++ AV ++ + VV TT P + VP+
Sbjct: 675 QDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVF 734
Query: 911 ----RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH----GQRLPISRNTFA 962
R+L + T + + W +S V +RV + E +P S+N
Sbjct: 735 QTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLL 794
Query: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
+ L P Y V + E ++A +T P NL+ E + + + W PP
Sbjct: 795 -LKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853
Query: 1022 AQITGYRLTV-GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
+ + GYR+ ++ G + VG ++ + NL +Y V + A + + S TG
Sbjct: 854 SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913
Query: 1081 VFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSI- 1138
+ TL G +++ + E+ T++ W V S +E T G+
Sbjct: 914 MVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTR 971
Query: 1139 -VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
GL P E Y I V QE + P V+ + S PT
Sbjct: 972 HCFYGLQPDSE--YKISVYTKLQEIEGPSVSIMEKTQSLPT 1010
Score = 50.1 bits (118), Expect = 3e-05
Identities = 21/70 (30%), Positives = 36/70 (51%)
Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
+ SI + W P+ GY+++ +P+ G + +LNL TA + L P Y + I
Sbjct: 41 ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQII 100
Query: 882 AVEENQESTP 891
A +++ES P
Sbjct: 101 AYNKDKESKP 110
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 1816 PSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1875
P+ LR+ + +S+ +SW+ PR + GY + P S + + T+A I GL P
Sbjct: 33 PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVT-PTSGGKTNQLNLQNTATKAIIQGLMP 91
Query: 1876 GTEYTIYVIALKNNQKSEPLIGR-------KKTDELPQLVTLPHPNLHGPEILDVPSTVQ 1928
YT+ +IA +++S+P G+ K+ D P++ + N P + V
Sbjct: 92 DQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVKFVC 151
Query: 1929 KTPFV 1933
+TP +
Sbjct: 152 QTPAI 156
Score = 45.8 bits (107), Expect = 5e-04
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
++ P++++ + +SI + W GY++ TP +G G T T+ I+
Sbjct: 29 QVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQ 87
Query: 1601 GLQPTVEYVVSVYAQNPSGESQP 1623
GL P Y V + A N ES+P
Sbjct: 88 GLMPDQNYTVQIIAYNKDKESKP 110
Score = 41.6 bits (96), Expect = 0.009
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 1724 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1783
V+PP R R + +I ISW+ G+++ P +G Q ++ I GL
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGL 89
Query: 1784 QPGTDYKIYLYTLNDNARSSP 1804
P +Y + + N + S P
Sbjct: 90 MPDQNYTVQIIAYNKDKESKP 110
Score = 32.3 bits (72), Expect = 5.5
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 11/123 (8%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
I+ S +SW + G+++ + G Q L+L +TAT I L+P + Y V +
Sbjct: 41 ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTATKAIIQGLMPDQNYTVQI 99
Query: 791 YQISEDGEQSLILSTSQTTAPD----APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
++D E + Q D P P V VD + SRP +P + +
Sbjct: 100 IAYNKDKESK--PAQGQFRIKDLEKRKDPKPRVKVVDRGN----GSRPSSPEEVKFVCQT 153
Query: 847 PSV 849
P++
Sbjct: 154 PAI 156
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 159 bits (402), Expect = 3e-38
Identities = 149/537 (27%), Positives = 234/537 (43%), Gaps = 31/537 (5%)
Query: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
F +GV+ + E PR++T S + G G+ Q L+ G R P
Sbjct: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
+ L PT+L L + + +SW + + Y I + G G E VV
Sbjct: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286
+S NL+ EY VSV+ + + + + A +PPP L + P T+ +T
Sbjct: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
Query: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342
W P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+
Sbjct: 487 WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542
Query: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
E E+ +R R T L P + FSD++ ++ V W + R+ + G
Sbjct: 543 EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600
Query: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461
+ P + S TL L+ T Y V + L S L G+ +T + P L +
Sbjct: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660
Query: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ A
Sbjct: 661 DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719
Query: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
G A S P+S+ Y PS + + +S+ V W P V Y +T
Sbjct: 720 YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776
Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T PA
Sbjct: 777 PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
Score = 148 bits (373), Expect = 7e-35
Identities = 125/457 (27%), Positives = 200/457 (43%), Gaps = 19/457 (4%)
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
P + + +P PT L + + ++R++W P P L +V + E+ +
Sbjct: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA--SRGGTPREVVVE 425
Query: 1318 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTV 1376
+ L NL TEY+VSV +YE LRG T L P + + +T + +
Sbjct: 426 GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485
Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
W P A T Y +R P G E V R + L L PG +Y VS+ +L G E
Sbjct: 486 TW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544
Query: 1437 SPLL-IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQEF 1494
S I ++ PR L + + + W+ VR R+TY GG+S E
Sbjct: 545 SEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTE- 603
Query: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554
PG+ ++AT+ L YT+ V + G S + ++ + PSQ+ +T++
Sbjct: 604 -APGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTK---KAPSPSQLSMTELP 659
Query: 1555 DNSISVKWLPSS-SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
+++ + W+ ++ S V Y++T TP G G + + + GL EY V++
Sbjct: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
Query: 1614 AQNPSG-ESQPL----VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668
A G S P+ + V+ P P++L TP SL WTPP ++ Y + P
Sbjct: 719 AYYRDGARSDPVSLRYTPSTVSRSP-PSNLALASETPDSLQVSWTPPLGRVLHYWLTYAP 777
Query: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1705
GP K +++ S V + L ATKY V V A+
Sbjct: 778 ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAI 814
Score = 145 bits (367), Expect = 3e-34
Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130
++ P A TL +S+ ++VT ++I ++WTPAPR K + R S+GG PRE
Sbjct: 365 RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421
Query: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187
V + + S + L EY+ ++ + +G + PL PP L L A P
Sbjct: 422 VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481
Query: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
T LT W+ S T Y + +P + +G E V + D L PG +Y VSV
Sbjct: 482 TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
Query: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304
+++ + S P + PP L F+++ D RV W AP P LVR +
Sbjct: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591
Query: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362
V +E + + +P + + L L T Y V V+ +Y S+ L GR T SP+
Sbjct: 592 VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651
Query: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421
+ +++ ++ + W+A + + Y+I P G+ E VP + + L L
Sbjct: 652 QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710
Query: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
TEY V+I+A +G P+ + STVS P +L + + TP SL +SW P V +
Sbjct: 711 TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770
Query: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
Y +TY G P + +VPG++S T+ L+ Y + V A+ G S A S
Sbjct: 771 YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
Score = 127 bits (320), Expect = 1e-28
Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)
Query: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
P A L APT+L T S++ + WTP Y + +R G PR+ V
Sbjct: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103
+ L NL +EY VS+ I G+ TT + +PP VT T+
Sbjct: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
Query: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
+TW P A + +G E REV +++ GL PG +Y ++Q LR +
Sbjct: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
Query: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
+A + L+PP +L ++ V WE + P + R+T + G G+S
Sbjct: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279
+ + +S T LS Y V V + S ++ + P P+ L T +
Sbjct: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
D +++ W + + + ++P+ E E+S+ + VL L TEY V++
Sbjct: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
Query: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395
+ Y + + LR T P+ + + T +S V W P + Y + + P
Sbjct: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778
Query: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443
G + VP +R+ +TL +L T+Y +VS + GR E+ GQ
Sbjct: 779 SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828
Score = 115 bits (288), Expect = 5e-25
Identities = 119/490 (24%), Positives = 213/490 (43%), Gaps = 26/490 (5%)
Query: 1451 PRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
P L + T +S+ +SW AP ++Y + GG +E V G ++ + L
Sbjct: 380 PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTP--REVVVEGPAASTELHNLA 437
Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
+Y ++V+ + G ++ + P + + V ++ + W PS+
Sbjct: 438 SRTEYLVSVFPIYEGGVGEGLRGLVTT---APLPPPRALTLAAVTPRTVHLTWQPSAG-A 493
Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA-QNPSGESQPLVQTA 1628
T Y V +P + G + + + E+ ++GL+P +Y VSV + + P G ++
Sbjct: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRAR 553
Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQW--TPPNVQLTGYRVRVTPKEKTGPMKEINLAP-DSS 1685
T+ P L F+ V+ + W P V+L VRVT G AP +++
Sbjct: 554 TPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL----VRVTYVSSEGGHSGQTEAPGNAT 609
Query: 1686 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745
S + L +T Y V V L S G VTT + SP + + +T+ + ++W
Sbjct: 610 SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLS-MTELPGDAVQLAWV 668
Query: 1746 TKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNARSS 1803
+ + +Q+ P + ++ ++ + + GL T+Y + + D ARS
Sbjct: 669 AAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSD 728
Query: 1804 PVVI---DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY-EKPGSPPREVVP 1859
PV + ++ + PSNL + TP+SL VSW PP R+ Y + Y G P + V
Sbjct: 729 PVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVS 788
Query: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 1919
P + T+ L+ T+Y + V A+ +SE + +T P L P +L G +
Sbjct: 789 VP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT-ACPAL--RPDGSLPGFD 844
Query: 1920 ILDVPSTVQK 1929
++ S V+K
Sbjct: 845 LMVAFSLVEK 854
Score = 104 bits (259), Expect = 1e-21
Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)
Query: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954
+Q P DT+P+P L +VT + + WTP Y + V + G + +
Sbjct: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013
E+ L+ Y VF + G + L TT L P L T TV
Sbjct: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
Query: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
+ W P A T Y + + +G+ + V + L L+P +Y VS+ +++G
Sbjct: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
Query: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127
E +A G+ + + PP + ++V+ + W APR + V S+GG +
Sbjct: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
Query: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185
+ E ++ S + L+ Y + L G + + +V T +P P+ L +
Sbjct: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
P V ++W + + Y+IT TP +G + E V + + L EY+V
Sbjct: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
Query: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
++ +D S P+S P+ PP++L + PD+++V+W PP + ++ +
Sbjct: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774
Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
Y+P +S+ + + V L +L T+Y V VS++Y S + +T
Sbjct: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
Score = 102 bits (255), Expect = 3e-21
Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)
Query: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648
CQ LQ GP +T P +S + W P P H KY++ WR
Sbjct: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
G +E + G S + L Y + I + G E R TT+ P
Sbjct: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
P T +VT T ++W S + + V + E + ++
Sbjct: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826
V + L PGR Y V+V + E E I + + T AP P V +
Sbjct: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
Query: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
V W P+ R+ Y S G S + P A S TL L Y + + +
Sbjct: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945
S+ + TG + PSP L E+ V + W S V Y++ P+
Sbjct: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001
H +P + T A + GL Y + A G S P++ + T P+
Sbjct: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
Query: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+
Sbjct: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
Query: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098
+Y V + AI G E+ ATG L+P S+P ++ V
Sbjct: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
Score = 94.4 bits (233), Expect = 1e-18
Identities = 112/484 (23%), Positives = 182/484 (37%), Gaps = 42/484 (8%)
Query: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
Q S P A+ T+PAPT L +QVT +S+ WTP Y + V + G
Sbjct: 360 QGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGT 418
Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734
+E+ + ++S + L T+Y VSV+ + + +G+VTT + PPR +
Sbjct: 419 PREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAP-LPPPRALTLAA 477
Query: 1735 ATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
T T+ ++W+ T + V PA+ + +R ++ + GL+PG DY++ +
Sbjct: 478 VTPRTVHLTWQPSAGA-THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
Query: 1794 YTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKP 1850
+L S I A T + P +L F + ++ V W+ P R+ +
Sbjct: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEG 596
Query: 1851 GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP----- 1905
G + P T AT+ L T YT+ V L S L GR T + P
Sbjct: 597 GHSGQTEAP---GNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQL 653
Query: 1906 QLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-GYDTGNGIQLPGTSGQQ--PSVGQQMIF 1962
+ LP + + PS V P G + I +PG G P +G+ +
Sbjct: 654 SMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEY 713
Query: 1963 EEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTG 2022
+ + P+ R Y P+ + P N +
Sbjct: 714 DVTILAYYRDGARSDPVSLR---YTPST-----VSRSPPS---------------NLALA 750
Query: 2023 QEALSQTTISWA-PFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081
E +SW P Y ++ P VPG + TL L Y ++
Sbjct: 751 SETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVL 810
Query: 2082 VEAL 2085
V A+
Sbjct: 811 VSAI 814
Score = 74.7 bits (182), Expect = 1e-12
Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648
Y G+GE + T P P +T P + + W QPS + Y++R P
Sbjct: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
+ G +E + + GL+PG YE + S++ E T + + P
Sbjct: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
++++ + V W A V RV Y SE G Q +
Sbjct: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
P ATS + L Y V V + G S + T +P ++ ++ ++
Sbjct: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
Query: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886
+ W + + + Y+I ++P EG + E+++P + L L +Y++TI A +
Sbjct: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945
S PV ++ TP + + P +L T + + WTPP V Y + P +
Sbjct: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999
L E +P +R + + L Y V A+ S+ ++A T A
Sbjct: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
Score = 65.5 bits (158), Expect = 6e-10
Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)
Query: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663
T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L
Sbjct: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
+ + GL Y+ +++ + G + + S T +TV+ +P S L
Sbjct: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
SE T S VSW V + + Y + + + +P + V +PDL
Sbjct: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842
KY V V I G + +T QT P PD ++ D ++V +S + R
Sbjct: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
Query: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872
+ PS G + L + A + +SD+ P
Sbjct: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
Score = 32.3 bits (72), Expect = 5.5
Identities = 15/64 (23%), Positives = 27/64 (42%)
Query: 2031 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090
++W P + Y++ C P E + V L GL G Y + V++L+ +
Sbjct: 485 LTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544
Query: 2091 HKVR 2094
+ R
Sbjct: 545 SEAR 548
>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
[Homo sapiens]
Length = 2215
Score = 152 bits (383), Expect = 5e-36
Identities = 263/1257 (20%), Positives = 461/1257 (36%), Gaps = 97/1257 (7%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H SY GL PG +Y L + + + R+ T+ P+
Sbjct: 469 HATSYAFHGLTPGYLYN--LTVMTEAAGLQNYRWKLVRTA------------------PM 508
Query: 722 VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
++ VT + + +S V W V + + LS +G + L T + +L
Sbjct: 509 EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKEL 566
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-SIVVRWSRPQAPIT 839
+PGR Y V V +S GE S T PD + + S+VV WS P
Sbjct: 567 VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 624
Query: 840 GYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
YRI+ ++ SV + + ET + + L PG QY + + N +++
Sbjct: 625 QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERC----- 679
Query: 899 TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
+ TVP + L+ + ++IMW P + Y + + +L H + L
Sbjct: 680 ----QGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 734
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
F T L PG Y V ++S ++ +T T+L N+ S++
Sbjct: 735 AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 792
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
WT + + Y++ + + + ++ S+Y +L+ S Y+V + + G S
Sbjct: 793 WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
+ T+ S N + ++W AP V S G+ + +
Sbjct: 852 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 911
Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
S LTPG Y TI E + + V ++ A D L VS
Sbjct: 912 VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 969
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
W +T D Y +T N N ++ + + ++ C F L PG Y+V+V T
Sbjct: 970 WVHATG-DFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024
Query: 1254 KESVPISDTIIPAVPPPT-DLRFTNIGPDTMRVTWAPPPS-IDLTNFLVRYSPVKNEEDV 1311
E+ + +P P DL N + + VTW+ +D + ++ +K
Sbjct: 1025 YEANEQGNG--RTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKV---F 1079
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
+ + T+L PG +Y + V ++ + + G P+ + I+
Sbjct: 1080 PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI----EGFTVPSAVKNIHISP 1135
Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
N S TV+W + Y + RH S + +P T L G +Y
Sbjct: 1136 NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 1190
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
+ I +++G ++ + + ++ + V + A + SL++SW A V RY +
Sbjct: 1191 QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1250
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
E G ++ + P + L PG Y I + V+G SK RT
Sbjct: 1251 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGG----LFSKEAQTEGRTVPA 1304
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
+ +++T+ +S +W S ++ Y + +G + + Q+ LQ
Sbjct: 1305 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1364
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTG 1661
+ +V V SGE T+PA + T SL W+P +
Sbjct: 1365 GRMYKMVIV---THSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDF 1421
Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721
Y + + G KE D + GL+ KY + V L+++ T
Sbjct: 1422 YELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTA- 1478
Query: 1722 ENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
SPP D T++ I+W+ + F++ +P + T
Sbjct: 1479 --PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI 1536
Query: 1780 ITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 1836
+ GL+PG Y+ + T++ ++ S P+ T D NL ++ SW PP
Sbjct: 1537 VYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPP 1596
Query: 1837 RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1893
+ GY I+ K + E + + I L P Y + + SE
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSE 1653
Score = 146 bits (369), Expect = 2e-34
Identities = 255/1269 (20%), Positives = 485/1269 (38%), Gaps = 109/1269 (8%)
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
++ L+ G +Y ++IS+ + TV +T P P S
Sbjct: 300 LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 337
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
+ T++S V W +S V+ + V+ E + Q + + + + +L G K
Sbjct: 338 KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 396
Query: 786 YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Y + + +S G++S + T+ +T P D + S+++ WS + YR++
Sbjct: 397 YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 454
Query: 846 SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
V G + + A S L PG YN+T+ ++ + +
Sbjct: 455 MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 505
Query: 903 RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
+P ++ ++VT+ + + W P V Y + + E P I+
Sbjct: 506 ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
F E L PG Y V VS G S A T D NL+ N +++V
Sbjct: 560 ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 615
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
W+PP YR+ + VG ++Y + + L P +Y V ++ GN +
Sbjct: 616 WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 674
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
+ + T P + + ET++ I W TP A + + + + ++
Sbjct: 675 NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 732
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
D+ + L PG +Y+ T+ + + + + + V + T+LH+ T L
Sbjct: 733 KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 790
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
+W ++ D+ Y++ N N E + ++ S +F +L G Y+V V TV
Sbjct: 791 TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 846
Query: 1253 DKES--VPISDTIIPAVPPPTDLRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
S V + +P+ + + N G D + V+W P D+ N+ V S + +
Sbjct: 847 GISSRQVVVEGRTVPS--SVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGK 901
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDF 1366
V L I+ S ++L PG Y V++ S YE H + +++T D G+
Sbjct: 902 VVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSV 957
Query: 1367 SDITANSFT-VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
S+ + + V W+ Y + ++ + + +P S N L PG Y
Sbjct: 958 SNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYS 1015
Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YG 1483
V++ +G+ E+ G T+ + +DL + + L ++W V Y I +
Sbjct: 1016 VTVTTKSGQYEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFN 1074
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+ P F + + + + L PG Y I V ++G A + ++ +
Sbjct: 1075 DMKVFPP---FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNI 1131
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
S TD S++V W P V Y V+ + ++T E T L+
Sbjct: 1132 HISPNGATD----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLE 1185
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTG 1661
+Y + + + + S ++Q + T+PA + + SL W
Sbjct: 1186 AGEQYQIMIASVSGSLKNQ--INVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAER 1243
Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721
Y + + E ++ + + L KY++ + + L S+ AQ T+
Sbjct: 1244 YDILLLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTV 1302
Query: 1722 ENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1781
+ R+T+ + ++ W ++ + + +G + + P V+S++
Sbjct: 1303 P--AAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQ 1360
Query: 1782 GLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFL-ATTPNSLLVSWQPPRARI 1840
L G YK+ + T + S+ I T + S+LR T +SL +W P
Sbjct: 1361 NLLQGRMYKMVIVT-HSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDF 1419
Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
Y + P +E +TE GL PG +Y ++V+ + ++ +
Sbjct: 1420 DFYELILYNPNGTKKE--NWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRT 1477
Query: 1901 TDELPQLVT 1909
P L++
Sbjct: 1478 APSPPSLMS 1486
Score = 130 bits (328), Expect = 1e-29
Identities = 236/1130 (20%), Positives = 443/1130 (39%), Gaps = 103/1130 (9%)
Query: 798 EQSLILSTSQ----TTAPDAPPDP-------TVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
+ S +LST+Q TT +P + S+ ++W +P + ++YS
Sbjct: 219 DTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRILGSPCN-FSLIYS 277
Query: 847 PSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
G++ + T L DLQ G YN I +++E + VV+Q +
Sbjct: 278 SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERT---VVLQ--------T 326
Query: 905 DTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
D +P R + + T + + WTP VT Y V + N G ++ S ++ E
Sbjct: 327 DPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQES-TSWNE 385
Query: 964 VT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
T L+ G Y + AVS G+ S + +T + +P ++ +++L+ W+
Sbjct: 386 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSPVKDIGISTKANSLLISWSHGS 444
Query: 1022 AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
+ YRL + G+ G V + Y L P Y ++++ ++ +
Sbjct: 445 GNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRW 500
Query: 1079 TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGG--EAPREVTSDSG 1136
V T S++ N + + T++ + W P + S G + R +
Sbjct: 501 KLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVS 1194
L PG Y T+ + V + P +LEAN + + L VS
Sbjct: 560 ETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF----PDKVANLEANNNGRMRSLVVS 615
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVYTVKD 1252
W D YRI L V +++ D+ L PG +Y V V
Sbjct: 616 WS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESG 671
Query: 1253 D-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV 1311
+ K S +P LR + ++ + W P + + +++ S + +
Sbjct: 672 NLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTPVA-EWEKYII--SLADRDLLL 726
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
S+S T+L+PG +Y+ +V+S+ + S+ ++GR + + +T
Sbjct: 727 IHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT 786
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
++ FT +W + + Y++ E+ + + + + + +L G+ Y V +
Sbjct: 787 SSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSETSRYSFHSLKSGSLYSVVVTT 843
Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LLISWDAPAVTVRYYRITYGETG 1486
++G S ++ + T VP + V + L +SW V Y +T G
Sbjct: 844 VSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG 900
Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
VQ + S + S L PG YT+T+ +G+ ++ + S+ RT DK
Sbjct: 901 --KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQE-----RTVPDKVQ 953
Query: 1547 QMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
+ V++ + + + V W+ ++ Y VT KN +TK+ + E L P
Sbjct: 954 GVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NFIQTKSIPKSENECVFVQLVPG 1011
Query: 1606 VEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRV 1664
Y V+V + SG+ + Q TIP P DL + L W+ N + Y +
Sbjct: 1012 RLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEI 1069
Query: 1665 RVTPKE-KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK-DTLTSRPAQG--VVTT 1720
++ + K P +L ++ + L +Y++ V + D S +G V +
Sbjct: 1070 QLLFNDMKVFP--PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSA 1127
Query: 1721 LEN--VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
++N +SP + ++T++W + + V A + Q +TI V +
Sbjct: 1128 VKNIHISP-------NGATDSLTVNWTPGGGDVDSYTVSAF-RHSQKVDSQTIPKHVFEH 1179
Query: 1779 TITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRA 1838
T L+ G Y+I + +++ + ++ V+ + + A + SL+VSWQ
Sbjct: 1180 TFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAG 1239
Query: 1839 RITGY-IIKYEKPGSPPREVVPRPRPGVT-EATITGLEPGTEYTIYVIAL 1886
Y I+ + G R P T + L PG +Y I ++ +
Sbjct: 1240 VAERYDILLLTENGILLRNT---SEPATTKQHKFEDLTPGKKYKIQILTV 1286
Score = 119 bits (299), Expect = 3e-26
Identities = 262/1207 (21%), Positives = 441/1207 (36%), Gaps = 122/1207 (10%)
Query: 660 PGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP-- 717
PG+++SY I G + E ++++ T F VT + V+GE +
Sbjct: 532 PGNVDSYNITLSHKGTIKESRVLA----PWITETHFKELVPGRLYQVTVSCVSGELSAQK 587
Query: 718 ------FSPLVATSESVTEITASSFVVSWVSASDTVSGFR--------VEYELSEEGDEP 763
F VA E+ S VVSW + +R V ++ +E
Sbjct: 588 MAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEET 647
Query: 764 QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVD 823
QY+ ++ L+PGR+Y V V I E G T P A V +
Sbjct: 648 QYV--------MDDTGLVPGRQYEVEV--IVESGNLKNSERCQGRTVPLAVLQLRVKHAN 697
Query: 824 DTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
+TS+ + W P A Y I+ + +L + A T +DL PG +Y T+ ++
Sbjct: 698 ETSLSIMWQTPVAEWEKY-IISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSI 756
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM---------WTPPESAV 934
+ +++ V + TVP+ +VTD+ V WT + V
Sbjct: 757 SGDLKNSSSV---------KGRTVPA-------QVTDLHVANQGMTSSLFTNWTQAQGDV 800
Query: 935 TGYRVDVIPVNLPGEHGQ-RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
Y+V +I N+ ++ SR +F L G Y V VS G S+ + +
Sbjct: 801 EFYQVLLIHENVVIKNESISSETSRYSFHS---LKSGSLYSVVVTTVSGGISSRQVVVEG 857
Query: 994 TTKLDAPTNLQFVNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKY 1051
T + + + N + L V W + Y +T L+ G+ Q V SV +
Sbjct: 858 RTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVT--LSHDGKVVQSLVIAKSVREC 915
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+L P YTV++ G E+ + T + N+ ++ + ++W A
Sbjct: 916 SFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDY-LRVSWVHAT 974
Query: 1112 RI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
+++ ++ + + V L PG Y T+ + GQ N
Sbjct: 975 GDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT-KSGQYEANEQGNG 1033
Query: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P P +L L N T L V+W D+ Y I + + V A +
Sbjct: 1034 RTIP-EPVKDLTLR-NRSTEDLHVTWS-GANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 1090
Query: 1230 SSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGP----DTMRV 1285
F +L+PG +Y + V T+ D + I P+ ++ +I P D++ V
Sbjct: 1091 YR--FTSLTPGRQYKILVLTISGDVQQ----SAFIEGFTVPSAVKNIHISPNGATDSLTV 1144
Query: 1286 TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQH 1345
W P D+ ++ V S ++ + V +I L G +Y + ++SV
Sbjct: 1145 NWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASV---- 1197
Query: 1346 ESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIRHHPEHFSGR 1400
S L+ + G P + +D +S++ V W Y I E+
Sbjct: 1198 -SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTEN-GIL 1255
Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
R P + +LTPG +Y + I+ ++G S + TV DL + +
Sbjct: 1256 LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENS 1315
Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
L W A + +Y I GN + P +S + L G Y + +
Sbjct: 1316 TRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQGRMYKMVIVT 1374
Query: 1521 VTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1576
+G + + + P S+++ + S TD S+ W P+S Y +
Sbjct: 1375 HSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASGDFDFYELIL 1426
Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT 1636
N G K D TE +GL P +YV+ V SG+ V T P+P
Sbjct: 1427 YNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTAESRTAPSPP 1482
Query: 1637 DL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1693
L F + TSL+ W PP+ + ++ P++ N S +V GL
Sbjct: 1483 SLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIVYGLR 1541
Query: 1694 VATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1750
Y+ +V + S+P G V T + R ++ T I SW
Sbjct: 1542 PGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIPPDSD 1599
Query: 1751 ITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1809
G+ ++ + Q R ++ + I L P Y + + + S V
Sbjct: 1600 FDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDST 1659
Query: 1810 STAIDAP 1816
T ID P
Sbjct: 1660 ITMIDRP 1666
Score = 35.4 bits (80), Expect = 0.65
Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)
Query: 628 IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
I W P + + + L+W P++++ + G + + GL+PG Y+ + +
Sbjct: 1497 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1552
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
+ + ++ F + T N L ++ T I S W+
Sbjct: 1553 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1596
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
G+ +E + + L + +NI L+P ++Y+V++ ++ G S ++
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1655
Query: 804 STSQTTAPDAPPDP 817
S T D PP P
Sbjct: 1656 EDSTITMIDRPPPP 1669
>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
precursor [Homo sapiens]
Length = 1997
Score = 152 bits (383), Expect = 5e-36
Identities = 263/1257 (20%), Positives = 461/1257 (36%), Gaps = 97/1257 (7%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H SY GL PG +Y L + + + R+ T+ P+
Sbjct: 251 HATSYAFHGLTPGYLYN--LTVMTEAAGLQNYRWKLVRTA------------------PM 290
Query: 722 VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
++ VT + + +S V W V + + LS +G + L T + +L
Sbjct: 291 EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKEL 348
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-SIVVRWSRPQAPIT 839
+PGR Y V V +S GE S T PD + + S+VV WS P
Sbjct: 349 VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 406
Query: 840 GYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
YRI+ ++ SV + + ET + + L PG QY + + N +++
Sbjct: 407 QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERC----- 461
Query: 899 TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
+ TVP + L+ + ++IMW P + Y + + +L H + L
Sbjct: 462 ----QGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 516
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
F T L PG Y V ++S ++ +T T+L N+ S++
Sbjct: 517 AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 574
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
WT + + Y++ + + + ++ S+Y +L+ S Y+V + + G S
Sbjct: 575 WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
+ T+ S N + ++W AP V S G+ + +
Sbjct: 634 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 693
Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
S LTPG Y TI E + + V ++ A D L VS
Sbjct: 694 VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 751
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
W +T D Y +T N N ++ + + ++ C F L PG Y+V+V T
Sbjct: 752 WVHATG-DFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 806
Query: 1254 KESVPISDTIIPAVPPPT-DLRFTNIGPDTMRVTWAPPPS-IDLTNFLVRYSPVKNEEDV 1311
E+ + +P P DL N + + VTW+ +D + ++ +K
Sbjct: 807 YEANEQGNG--RTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKV---F 861
Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
+ + T+L PG +Y + V ++ + + G P+ + I+
Sbjct: 862 PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI----EGFTVPSAVKNIHISP 917
Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
N S TV+W + Y + RH S + +P T L G +Y
Sbjct: 918 NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 972
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
+ I +++G ++ + + ++ + V + A + SL++SW A V RY +
Sbjct: 973 QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1032
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
E G ++ + P + L PG Y I + V+G SK RT
Sbjct: 1033 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGG----LFSKEAQTEGRTVPA 1086
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
+ +++T+ +S +W S ++ Y + +G + + Q+ LQ
Sbjct: 1087 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1146
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTG 1661
+ +V V SGE T+PA + T SL W+P +
Sbjct: 1147 GRMYKMVIV---THSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDF 1203
Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721
Y + + G KE D + GL+ KY + V L+++ T
Sbjct: 1204 YELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTA- 1260
Query: 1722 ENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
SPP D T++ I+W+ + F++ +P + T
Sbjct: 1261 --PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI 1318
Query: 1780 ITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 1836
+ GL+PG Y+ + T++ ++ S P+ T D NL ++ SW PP
Sbjct: 1319 VYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPP 1378
Query: 1837 RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1893
+ GY I+ K + E + + I L P Y + + SE
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSE 1435
Score = 146 bits (369), Expect = 2e-34
Identities = 255/1269 (20%), Positives = 485/1269 (38%), Gaps = 109/1269 (8%)
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
++ L+ G +Y ++IS+ + TV +T P P S
Sbjct: 82 LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 119
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
+ T++S V W +S V+ + V+ E + Q + + + + +L G K
Sbjct: 120 KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 178
Query: 786 YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Y + + +S G++S + T+ +T P D + S+++ WS + YR++
Sbjct: 179 YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 236
Query: 846 SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
V G + + A S L PG YN+T+ ++ + +
Sbjct: 237 MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 287
Query: 903 RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
+P ++ ++VT+ + + W P V Y + + E P I+
Sbjct: 288 ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 341
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
F E L PG Y V VS G S A T D NL+ N +++V
Sbjct: 342 ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 397
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
W+PP YR+ + VG ++Y + + L P +Y V ++ GN +
Sbjct: 398 WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 456
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
+ + T P + + ET++ I W TP A + + + + ++
Sbjct: 457 NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 514
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
D+ + L PG +Y+ T+ + + + + + V + T+LH+ T L
Sbjct: 515 KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 572
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
+W ++ D+ Y++ N N E + ++ S +F +L G Y+V V TV
Sbjct: 573 TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 628
Query: 1253 DKES--VPISDTIIPAVPPPTDLRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
S V + +P+ + + N G D + V+W P D+ N+ V S + +
Sbjct: 629 GISSRQVVVEGRTVPS--SVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGK 683
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDF 1366
V L I+ S ++L PG Y V++ S YE H + +++T D G+
Sbjct: 684 VVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSV 739
Query: 1367 SDITANSFT-VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
S+ + + V W+ Y + ++ + + +P S N L PG Y
Sbjct: 740 SNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYS 797
Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YG 1483
V++ +G+ E+ G T+ + +DL + + L ++W V Y I +
Sbjct: 798 VTVTTKSGQYEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFN 856
Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+ P F + + + + L PG Y I V ++G A + ++ +
Sbjct: 857 DMKVFPP---FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNI 913
Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
S TD S++V W P V Y V+ + ++T E T L+
Sbjct: 914 HISPNGATD----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLE 967
Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTG 1661
+Y + + + + S ++Q + T+PA + + SL W
Sbjct: 968 AGEQYQIMIASVSGSLKNQ--INVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAER 1025
Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721
Y + + E ++ + + L KY++ + + L S+ AQ T+
Sbjct: 1026 YDILLLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTV 1084
Query: 1722 ENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1781
+ R+T+ + ++ W ++ + + +G + + P V+S++
Sbjct: 1085 P--AAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQ 1142
Query: 1782 GLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFL-ATTPNSLLVSWQPPRARI 1840
L G YK+ + T + S+ I T + S+LR T +SL +W P
Sbjct: 1143 NLLQGRMYKMVIVT-HSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDF 1201
Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
Y + P +E +TE GL PG +Y ++V+ + ++ +
Sbjct: 1202 DFYELILYNPNGTKKE--NWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRT 1259
Query: 1901 TDELPQLVT 1909
P L++
Sbjct: 1260 APSPPSLMS 1268
Score = 130 bits (327), Expect = 1e-29
Identities = 228/1091 (20%), Positives = 430/1091 (39%), Gaps = 92/1091 (8%)
Query: 826 SIVVRWSRPQAPITGYRIVYSPSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAV 883
S+ ++W +P + ++YS G++ + T L DLQ G YN I ++
Sbjct: 40 SVSIQWRILGSPCN-FSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISL 98
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
+E + VV+Q +D +P R + + T + + WTP VT Y V +
Sbjct: 99 DEERT---VVLQ--------TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLF 147
Query: 943 PVNLPGEHGQRLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
N G ++ S ++ E T L+ G Y + AVS G+ S + +T + +P
Sbjct: 148 DENNQKIQGVQIQES-TSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSP 205
Query: 1001 TNLQFVNETDSTVLVRWTPPRAQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQ 1057
++ +++L+ W+ + YRL + G+ G V + Y L
Sbjct: 206 VKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLT 261
Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
P Y ++++ ++ + V T S++ N + + T++ + W P
Sbjct: 262 PGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSY 320
Query: 1118 GVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
+ S G + R + L PG Y T+ + V +
Sbjct: 321 NITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF---- 376
Query: 1176 PPTNLHLEANPDTGV--LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
P +LEAN + + L VSW D YRI L V +++
Sbjct: 377 PDKVANLEANNNGRMRSLVVSWS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYV 432
Query: 1234 FDN--LSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
D+ L PG +Y V V + K S +P LR + ++ + W P
Sbjct: 433 MDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTP 490
Query: 1291 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTP 1349
+ + +++ S + + S+S T+L+PG +Y+ +V+S+ + S+
Sbjct: 491 VA-EWEKYII--SLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSS 547
Query: 1350 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1409
++GR + + +T++ FT +W + + Y++ E+ + + +
Sbjct: 548 VKGRTVPAQVTDLHVANQGMTSSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSE 604
Query: 1410 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LL 1465
+ + +L G+ Y V + ++G S ++ + T VP + V + L
Sbjct: 605 TSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLS 661
Query: 1466 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
+SW V Y +T G VQ + S + S L PG YT+T+ +G+
Sbjct: 662 VSWLLAPGDVDNYEVTLSHDG--KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKY 719
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584
++ + S+ RT DK + V++ + + + V W+ ++ Y VT KN
Sbjct: 720 ENHSFSQE-----RTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NF 772
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
+TK+ + E L P Y V+V + SG+ + Q TIP P DL
Sbjct: 773 IQTKSIPKSENECVFVQLVPGRLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNR 830
Query: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKE-KTGPMKEINLAPDSSSVVVSGLMVATKYEVSV 1702
+ L W+ N + Y +++ + K P +L ++ + L +Y++ V
Sbjct: 831 STEDLHVTWSGANGDVDQYEIQLLFNDMKVFP--PFHLVNTATEYRFTSLTPGRQYKILV 888
Query: 1703 YALK-DTLTSRPAQG--VVTTLEN--VSPPRRARVTDATETTITISWRTKTETITGFQVD 1757
+ D S +G V + ++N +SP + ++T++W + + V
Sbjct: 889 LTISGDVQQSAFIEGFTVPSAVKNIHISP-------NGATDSLTVNWTPGGGDVDSYTVS 941
Query: 1758 AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS 1817
A + Q +TI V +T L+ G Y+I + +++ + ++ V+ +
Sbjct: 942 AF-RHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQG 1000
Query: 1818 NLRFLATTPNSLLVSWQPPRARITGY-IIKYEKPGSPPREVVPRPRPGVT-EATITGLEP 1875
+ A + SL+VSWQ Y I+ + G R P T + L P
Sbjct: 1001 VIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNT---SEPATTKQHKFEDLTP 1057
Query: 1876 GTEYTIYVIAL 1886
G +Y I ++ +
Sbjct: 1058 GKKYKIQILTV 1068
Score = 119 bits (299), Expect = 3e-26
Identities = 262/1207 (21%), Positives = 441/1207 (36%), Gaps = 122/1207 (10%)
Query: 660 PGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP-- 717
PG+++SY I G + E ++++ T F VT + V+GE +
Sbjct: 314 PGNVDSYNITLSHKGTIKESRVLA----PWITETHFKELVPGRLYQVTVSCVSGELSAQK 369
Query: 718 ------FSPLVATSESVTEITASSFVVSWVSASDTVSGFR--------VEYELSEEGDEP 763
F VA E+ S VVSW + +R V ++ +E
Sbjct: 370 MAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEET 429
Query: 764 QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVD 823
QY+ ++ L+PGR+Y V V I E G T P A V +
Sbjct: 430 QYV--------MDDTGLVPGRQYEVEV--IVESGNLKNSERCQGRTVPLAVLQLRVKHAN 479
Query: 824 DTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
+TS+ + W P A Y I+ + +L + A T +DL PG +Y T+ ++
Sbjct: 480 ETSLSIMWQTPVAEWEKY-IISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSI 538
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM---------WTPPESAV 934
+ +++ V + TVP+ +VTD+ V WT + V
Sbjct: 539 SGDLKNSSSV---------KGRTVPA-------QVTDLHVANQGMTSSLFTNWTQAQGDV 582
Query: 935 TGYRVDVIPVNLPGEHGQ-RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
Y+V +I N+ ++ SR +F L G Y V VS G S+ + +
Sbjct: 583 EFYQVLLIHENVVIKNESISSETSRYSFHS---LKSGSLYSVVVTTVSGGISSRQVVVEG 639
Query: 994 TTKLDAPTNLQFVNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKY 1051
T + + + N + L V W + Y +T L+ G+ Q V SV +
Sbjct: 640 RTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVT--LSHDGKVVQSLVIAKSVREC 697
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+L P YTV++ G E+ + T + N+ ++ + ++W A
Sbjct: 698 SFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDY-LRVSWVHAT 756
Query: 1112 RI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
+++ ++ + + V L PG Y T+ + GQ N
Sbjct: 757 GDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT-KSGQYEANEQGNG 815
Query: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P P +L L N T L V+W D+ Y I + + V A +
Sbjct: 816 RTIP-EPVKDLTLR-NRSTEDLHVTWS-GANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 872
Query: 1230 SSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGP----DTMRV 1285
F +L+PG +Y + V T+ D + I P+ ++ +I P D++ V
Sbjct: 873 YR--FTSLTPGRQYKILVLTISGDVQQ----SAFIEGFTVPSAVKNIHISPNGATDSLTV 926
Query: 1286 TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQH 1345
W P D+ ++ V S ++ + V +I L G +Y + ++SV
Sbjct: 927 NWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASV---- 979
Query: 1346 ESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIRHHPEHFSGR 1400
S L+ + G P + +D +S++ V W Y I E+
Sbjct: 980 -SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTEN-GIL 1037
Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
R P + +LTPG +Y + I+ ++G S + TV DL + +
Sbjct: 1038 LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENS 1097
Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
L W A + +Y I GN + P +S + L G Y + +
Sbjct: 1098 TRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQGRMYKMVIVT 1156
Query: 1521 VTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1576
+G + + + P S+++ + S TD S+ W P+S Y +
Sbjct: 1157 HSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASGDFDFYELIL 1208
Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT 1636
N G K D TE +GL P +YV+ V SG+ V T P+P
Sbjct: 1209 YNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTAESRTAPSPP 1264
Query: 1637 DL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1693
L F + TSL+ W PP+ + ++ P++ N S +V GL
Sbjct: 1265 SLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIVYGLR 1323
Query: 1694 VATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1750
Y+ +V + S+P G V T + R ++ T I SW
Sbjct: 1324 PGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIPPDSD 1381
Query: 1751 ITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1809
G+ ++ + Q R ++ + I L P Y + + + S V
Sbjct: 1382 FDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDST 1441
Query: 1810 STAIDAP 1816
T ID P
Sbjct: 1442 ITMIDRP 1448
Score = 35.4 bits (80), Expect = 0.65
Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)
Query: 628 IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
I W P + + + L+W P++++ + G + + GL+PG Y+ + +
Sbjct: 1279 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1334
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
+ + ++ F + T N L ++ T I S W+
Sbjct: 1335 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1378
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
G+ +E + + L + +NI L+P ++Y+V++ ++ G S ++
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1437
Query: 804 STSQTTAPDAPPDP 817
S T D PP P
Sbjct: 1438 EDSTITMIDRPPPP 1451
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 152 bits (383), Expect = 5e-36
Identities = 154/599 (25%), Positives = 255/599 (42%), Gaps = 61/599 (10%)
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1429
TA S T+ W + Y + + P + + + ++ L+P +EY + +
Sbjct: 331 TATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVS 390
Query: 1430 ALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRYYRI 1480
A+N + P G+Q+ S PR+++ + T++++ W+ P +R YR+
Sbjct: 391 AVNSIGQGPPSESVVTRTGEQAPAS-APRNVQARMLSATTMIVQWEEPVEPNGLIRGYRV 449
Query: 1481 TYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
Y PV Q+ V S T T+ L YT+ V A T GD P S PI +
Sbjct: 450 YY-TMEPEHPVGNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSD-PIQVK 506
Query: 1538 YRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ + +P ++ + SI++ W P + G +T P T
Sbjct: 507 TQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPT-TS 565
Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQ--PLV-QTAVTTIPA--PTDLKFTQVTPTSLSAQ 1651
+E L+P EY + A++P G P+V Q + + P+ P D+K V T++
Sbjct: 566 YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVS 625
Query: 1652 WTPP-----NVQLTGYRVRVTPKEKTGPM-KEIN-LAPDSSSVVVSGLMVATKYEVSVYA 1704
W PP N L GY VR P P KE+N + P ++ +++ L T+Y ++ A
Sbjct: 626 WRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVA 685
Query: 1705 LKDTLTSRPAQGVVT-TLENV--SPPRRARVTDATETTITISWRTKTE-----TITGFQV 1756
+ + VV T E+V +PPR+ T I + WR+ I G+QV
Sbjct: 686 HTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQV 745
Query: 1757 -----DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL--YTLN-DNARSSPVVID 1808
+ A G I+ + D + IT LQP T Y I + YT+ D ARS P V+
Sbjct: 746 HYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVV 805
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
A+ L T SLL W+PP ++ GY +++ + S P + P P
Sbjct: 806 TKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFP-PS 864
Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHG-PEILD 1922
T +G+ G Y + A +S +G +E +++++P G P+IL+
Sbjct: 865 EDRYTASGVHKGATYVFRLAA-----RSRGGLG----EEAAEVLSIPEDTPRGHPQILE 914
Score = 120 bits (301), Expect = 2e-26
Identities = 192/881 (21%), Positives = 339/881 (38%), Gaps = 110/881 (12%)
Query: 752 VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
++ E SEE D+ +Y + + + V P Y+ ++ + IL S P
Sbjct: 192 LQIESSEETDQGKYECVATNSAGVRYSS--PANLYV----RVRRVAPRFSILPMSHEIMP 245
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+ T V V+W + E + E ++P N + L+D++
Sbjct: 246 GGNVNITCVAVGSPMPYVKWMQ--------------GAEDLTPEDDMPVGRNVLELTDVK 291
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
Y + E+ V Q P++ P E T +TI W
Sbjct: 292 DSANYTCVAMSSLGVIEA---VAQITVKSLPKAPGTP-----MVTENTATSITITWDSGN 343
Query: 932 -SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
V+ Y ++ + G + + I+ ++ + GLSP Y V AV+ + P
Sbjct: 344 PDPVSYYVIEYKSKSQDGPYQIKEDITTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSE 402
Query: 991 AQQT-----TKLDAPTNLQFVNETDSTVLVRW---TPPRAQITGYRLTVGLTRR---GQP 1039
+ T AP N+Q + +T++V+W P I GYR+ + G
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNW 462
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
+++NV S+ + +L YTV ++A + P + + Q G P N
Sbjct: 463 QKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAE 521
Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
+ET+I ++W+P PR I ++L R G + S VV L P EY +
Sbjct: 522 ARSETSITLSWSP-PRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFR 580
Query: 1153 IQVLR-DGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERSTTPD-----I 1203
+ G P+V + P +PP ++ + T +L VSW R P+ +
Sbjct: 581 LAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL-VSW-RPPPPETHNGAL 638
Query: 1204 TGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPI 1259
GY + P + E + + + L +Y ++ V ES P+
Sbjct: 639 VGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPV 698
Query: 1260 ---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEED-- 1310
+D +P+ PP + + +RV W +P P + + V Y ++ E
Sbjct: 699 VVRTDEDVPSAPP-RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARG 757
Query: 1311 ---VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR----QKTGLDSPTG 1363
+ ++ ++ + +V+TNL P T Y ++V++ + + + + + L PT
Sbjct: 758 PPRIKDVMLADAQE-MVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPT- 815
Query: 1364 IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
+ S W P T + GYR++ E + + P S + T + +
Sbjct: 816 LSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLE-FPPSEDRYTASGVH 874
Query: 1420 PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA-ATPTSLLISWDAPAVT 1474
G YV + A + G E + +L + T P+ LE A+ ++L+ W P
Sbjct: 875 KGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPA 934
Query: 1475 VRY-----YRITYGETGGNSPVQEFTVP-----GSKSTATISGLKPGVDYTITVYAVTGR 1524
R Y + E G P +E +P G+++ T+ GLKP Y + V A T R
Sbjct: 935 ERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRR 994
Query: 1525 GDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW 1562
G P S + YRT + P +V + S+ + W
Sbjct: 995 GPGPFSP---PVRYRTFLRDQVSPKNFKVKMIMKTSVLLSW 1032
Score = 111 bits (278), Expect = 7e-24
Identities = 179/799 (22%), Positives = 328/799 (41%), Gaps = 91/799 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
++T + S+ V T P + VTE TA+S ++W S + D VS + +EY
Sbjct: 295 NYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEY 354
Query: 755 ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTA 810
+ S+ D P + T T +I L P +Y + V ++ G+ +S++ T +
Sbjct: 355 K-SKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAP 413
Query: 811 PDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYSPSVE---GSSTELNLPETANS 864
AP + + T+++V+W P P I GYR+ Y+ E G+ + N+ ++
Sbjct: 414 ASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSL-L 472
Query: 865 VTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDV 921
T+ L Y + + A V + S P+ ++ + G P P +L+ ++
Sbjct: 473 TTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ-QGVP-----GQPMNLRAEARSET 526
Query: 922 KVTIMWTPP-ESAVTGYRVDVIPVNLPGEHGQRL--PISRNTFAEVTGLSPGVTYYFKVF 978
+T+ W+PP + ++ Y + + G+HG+ + T V L P Y F++
Sbjct: 527 SITLSWSPPRQESIIKYEL----LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLA 582
Query: 979 AVS-HGRES-KPLTAQQTTKLD---APTNLQFVNETDSTVLVRWTPP-----RAQITGY- 1027
A S G + P+ Q+T + P +++ V+ + +LV W PP + GY
Sbjct: 583 ARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYS 642
Query: 1028 -RLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-T 1084
R + +P++ N + P+ ++ L L+ ++Y ++ VA P+++ V T
Sbjct: 643 VRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRT 702
Query: 1085 LQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEA---PR-- 1129
+ S PP E + T I + W +PAP G+++ +G EA PR
Sbjct: 703 DEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIK 762
Query: 1130 -EVTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
+ +D+ +V++ L P Y T+ DG +V L PT L ++
Sbjct: 763 DVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPT-LSVQQT 821
Query: 1186 PDTGVLTVSWE--RSTTPD-ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLE 1242
P+ G L WE T D + GYR+ + +LE D+ + + +
Sbjct: 822 PE-GSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYV 880
Query: 1243 YNVSVYT---VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
+ ++ + + ++ V P P N T+ + W PP + +
Sbjct: 881 FRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAI 940
Query: 1300 VRYSPV---------KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---S 1347
V+Y+ E ++ + ++NA+ L L P T Y + V + + S
Sbjct: 941 VKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFS 1000
Query: 1348 TPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAP--RATITGYRIRHH--PEHFSGRPR 1402
P+R R SP I S + W P + T Y+I+++ GR
Sbjct: 1001 PPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTT 1060
Query: 1403 EDRV----PHSRNSITLTN 1417
+ + PH+ + LTN
Sbjct: 1061 KKLITHLKPHTFYNFVLTN 1079
Score = 103 bits (258), Expect = 1e-21
Identities = 188/791 (23%), Positives = 299/791 (37%), Gaps = 120/791 (15%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRW--KEATIPGHLNSYTIKGLKPGVV 676
T + S I W++ P +S Y++ ++ K+ G + KE Y+I GL P
Sbjct: 328 TENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSE 384
Query: 677 YEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSF 736
YE + ++ G + + T TGE P S + ++A++
Sbjct: 385 YEIWVSAVNSIGQGPPSE------------SVVTRTGEQAPAS--APRNVQARMLSATTM 430
Query: 737 VVSW---VSASDTVSGFRVEYELSEE---GDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
+V W V + + G+RV Y + E G+ ++ S T+V LL Y V V
Sbjct: 431 IVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVG--SLLEDETYTVRV 488
Query: 791 YQISEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP-QAPITGYRIVYS 846
+ G+ L I +Q P P + + +TSI + WS P Q I Y +++
Sbjct: 489 LAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFR 548
Query: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN--QESTPVVIQQETTGTPRS 904
G T S + DL+P +Y + A TPVV Q+ P +
Sbjct: 549 EGDHGREVGRTFDPT-TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSA 607
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRN 959
P+D++ V V + + W PP A+ GY V P+ G P +
Sbjct: 608 ----PPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPL------GSEDPEPK- 656
Query: 960 TFAEVTGLSPGVTY----------YFKVFAVSH-----GRESKPLTAQQTTKLDAPT--- 1001
EV G+ P T +++ V+H G ES P+ + T D P+
Sbjct: 657 ---EVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVR--TDEDVPSAPP 711
Query: 1002 ---NLQFVNETDSTVLVRWTPP---RAQITGYRL----TVGLTRRGQPRQYNVG-PSVSK 1050
+ +N T VL R P QI GY++ G RG PR +V +
Sbjct: 712 RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQE 771
Query: 1051 YPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI--PPYNTEVT-ETTIVI 1105
+ NLQP + Y++++ A +KG+ K V T G+ + P + + T E +++
Sbjct: 772 MVITNLQPETAYSITVAAYTMKGDGARSKPKVVVT---KGAVLGRPTLSVQQTPEGSLLA 828
Query: 1106 TWTPAPRIGFK--LGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEYVYTIQV-LR 1157
W P LG R G E A E SG+ G YV+ + R
Sbjct: 829 RWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSR 888
Query: 1158 DGQERDAPIVNKVV--TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT-- 1213
G +A V + TP P L N G + + W + G + T
Sbjct: 889 GGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVR 948
Query: 1214 -NGQQGNSLEEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
G G + E + A +++ T L P Y++ V + P S P V
Sbjct: 949 EAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQV-RAHTRRGPGPFS----PPV 1003
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLT-NFLVRY---SPVKNEEDVAELSISPSDNAV 1323
T LR + P +V S+ L+ F Y +P K + + L +
Sbjct: 1004 RYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKK 1062
Query: 1324 VLTNLLPGTEY 1334
++T+L P T Y
Sbjct: 1063 LITHLKPHTFY 1073
Score = 48.1 bits (113), Expect = 1e-04
Identities = 53/251 (21%), Positives = 103/251 (41%), Gaps = 28/251 (11%)
Query: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD----TLTSRPA 1714
+ G V +T PM + + + M + + + +KD T + +
Sbjct: 244 MPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSS 303
Query: 1715 QGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVPANGQTPI 1767
GV+ + ++ P VT+ T T+ITI+W + + ++ + ++ + P
Sbjct: 304 LGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPY 363
Query: 1768 QRTIKPDVRS--YTITGLQPGTDYKIYLYTLNDNARSSP-----VVIDASTAIDAPSNLR 1820
Q IK D+ + Y+I GL P ++Y+I++ +N + P AP N++
Sbjct: 364 Q--IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQ 421
Query: 1821 FLATTPNSLLVSWQ---PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA---TITGLE 1874
+ +++V W+ P I GY + Y P V + V ++ T+ L
Sbjct: 422 ARMLSATTMIVQWEEPVEPNGLIRGYRVYYTM--EPEHPVGNWQKHNVDDSLLTTVGSLL 479
Query: 1875 PGTEYTIYVIA 1885
YT+ V+A
Sbjct: 480 EDETYTVRVLA 490
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 148 bits (373), Expect = 7e-35
Identities = 273/1273 (21%), Positives = 467/1273 (36%), Gaps = 170/1273 (13%)
Query: 772 ATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTS 826
ATSV + L+P R Y + +++ G+ T + + P+ PP V + S
Sbjct: 647 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQS 706
Query: 827 IVVRWSRP-----QAPITGYRIVY--SPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
I+++W P + GY I Y + G + N++ L DL Y I
Sbjct: 707 IMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIE 766
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV----- 934
+ A N V + T T + P ++ + W P
Sbjct: 767 VAAY--NSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAE------VTGLSPGVTYYFKVFAVS---HGRE 985
GY+ +I E + +R F + V+GL Y+ V + G
Sbjct: 825 QGYK--LIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPR 882
Query: 986 SKPLTAQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPRQ 1041
S P + + P +L F D+++ V W P + +TGYR++ R R
Sbjct: 883 STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRV 942
Query: 1042 YNVGPSVS-KYPLRNLQPASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
+ P+V+ +Y + L + YT+ + A+ Q A+ + + + P PP N ++
Sbjct: 943 THYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGIS 1002
Query: 1100 E----------------TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVS 1141
T + W ++G V + ++++ D+ S+ V
Sbjct: 1003 NIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV---VGEGEEWLLIHQLSNEPDARSMEVP 1059
Query: 1142 GLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW- 1195
L P Y + + QV G + K+ T +P P N+ L +T L + W
Sbjct: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS-LWLRWM 1118
Query: 1196 -----ERSTTPDITGYRITTTPTNGQQGNSLEEVVH-ADQSSCTFDNLSPGLEYNVSVYT 1249
E + P+ GY+I + ++G G +L VV + T ++L EY V V
Sbjct: 1119 PLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQA 1177
Query: 1250 VKDDKESVPISDTII----PAVPP--PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
+ S P S T++ +VP PT++ +M V W+ P D ++ Y
Sbjct: 1178 F-NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYK 1236
Query: 1304 PVKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-----LRGR 1353
+ E+D L S + LT L Y V V + + +P L
Sbjct: 1237 VMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT 1296
Query: 1354 QKTGLDSPTGIDFSDITANSFTVHW---IAPRATITGYRIRHHPEHFSGRPREDRV-PHS 1409
P GI F ++ S + W AP I Y+I H + V S
Sbjct: 1297 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPS 1356
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA---ATPT 1462
T T L P + Y+ I A G L++ + P +V
Sbjct: 1357 ARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416
Query: 1463 SLLISWDAPA---VTVRYYRITYGE-TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
S+L+SW+ + VRYY I E G + +V + S+ + LKP Y V
Sbjct: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRV 1476
Query: 1519 YAVTGRGDSPAS--SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP-----VTG 1571
A GDS S S+ ++ + P+ + VT S+ ++W P + + G
Sbjct: 1477 KATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLG 1536
Query: 1572 YRV-------------TTTPKNGPGPTKTKTAG---------PDQTEMTIEGLQPTVEYV 1609
+R+ T N PG T + P T+ ++ L Y
Sbjct: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYE 1596
Query: 1610 V--SVY---AQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-----NVQL 1659
+ SVY + PS Q + AP ++ T T L W PP N +
Sbjct: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656
Query: 1660 TGYRVRVTPKEK---TGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK---DTLTSRP 1713
GY++ ++ T +K + LA +SV + L T Y VSV A D S P
Sbjct: 1657 QGYKIYFWEAQRGNLTERVKTLFLA--ENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTP 1714
Query: 1714 AQGVVTTLENVSPPRRARVTDATETTITISWRT---KTETITGFQVDAVPANGQTPIQRT 1770
QG T S P + ++ T T++ +SW + G+++ P + + +
Sbjct: 1715 TQG-QTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKI 1773
Query: 1771 IKPDVRSYT-----ITGLQPGTDYKIYL----YTLNDNARSSPVVIDASTAIDAPSNLRF 1821
+ DV+ + + L G Y+ + +T ++ V P +
Sbjct: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN-VTTGPGEGAPGPPGVPI 1832
Query: 1822 LATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA---TITGLEP 1875
+ +++ + W P + IT Y+I+ +++ + P + ++ L+P
Sbjct: 1833 IVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892
Query: 1876 GTEYTIYVIALKN 1888
G Y VIA+ +
Sbjct: 1893 GVSYDFRVIAVND 1905
Score = 142 bits (359), Expect = 3e-33
Identities = 293/1374 (21%), Positives = 509/1374 (37%), Gaps = 189/1374 (13%)
Query: 594 IGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQ-------------WNAPQP--SHI 638
IG + C+ + + S + + + P P HP+ W P S +
Sbjct: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPE-HPVATLSTVERRAINLTWTKPFDGNSPL 622
Query: 639 SKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFT 698
+YIL N+ A++ S T+KGL P Y+ +L ++ G + F
Sbjct: 623 IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ---FSKD 679
Query: 699 TTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT-----VSGFRVE 753
T S P T P ++A+ T S ++ W ++ + G+ +
Sbjct: 680 TERVSLPEEP-----PTAPPQNVIASGR-----TNQSIMIQWQPPPESHQNGILKGYIIR 729
Query: 754 YELSEEGDEPQYLDL-PSTATSVNIPDLLPGRKYIVNVYQISEDG---EQSLILSTSQTT 809
Y L+ Q+ ++ + ++ + DL+ Y + V + G S + +
Sbjct: 730 YCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQG 789
Query: 810 APDAPP-DPTVDQVDDTSIVVRWSRPQAPI-----TGYRIV-YSPSVEGSSTEL----NL 858
P PP + + + T+I W+ P GY+++ + P E T + N
Sbjct: 790 VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNF 849
Query: 859 PETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTPRSDTVPSP-RDLQ 914
++ + +S L+ +Y ++ + STP +++ + VP P L
Sbjct: 850 QDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH-------EDVPGPVGHLS 902
Query: 915 FVEVTDVKVTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
F E+ D + + W P +TGYR+ N + VTGL+
Sbjct: 903 FSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT 962
Query: 972 TYYFKVFAVSHGRESKPLTAQQTTKL-----DAPTNLQFVNETDSTVLVRWTP---PRAQ 1023
TY +V A++ + + + ++ + PTNL N +V +++ P +
Sbjct: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
Query: 1024 ITGY--RLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVSL--VAIKGNQES 1075
I+ + VG+ G+ Q + P + +L P + Y+ + V I G
Sbjct: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAPR---------IGFKLGVRPSQ 1123
+ + TLQ + P N + +ET++ + W P P +G+K+ S
Sbjct: 1083 SQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSD 1142
Query: 1124 G-GEAPREVTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV------TPL 1174
G G+ V D + L E Y +QV P VV P
Sbjct: 1143 GHGKTLSHVVQDRVERDYTIEDLEEWTE--YRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200
Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
S PTN+ A + +L V W D + GY++ + V
Sbjct: 1201 SGPTNVSALATTSSSML-VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
Query: 1231 SCTFDNLSPGLEYNVSVYT---VKDDKES-VPISDTIIPAVP-PPTDLRFTNIGPDTMRV 1285
S L + Y V V + D S PI + + VP PP + F + ++R+
Sbjct: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL 1319
Query: 1286 TWAPP--PSIDLTNFLVRYSPVKNEEDVAELSI-SPSDNAVVLTNLLPGTEYVVSVSSVY 1342
W PP P+ + + + + + A + + +PS T L P + Y+ +++
Sbjct: 1320 IWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
Query: 1343 -----EQHESTPLRGRQKTGLDSPTG--IDFSDITANSFTVHWIAPR---ATITGYRIRH 1392
E E+ + ++ P+ + D+ A S + W + + Y I+
Sbjct: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQT 1439
Query: 1393 HPEHFSGR--PREDRVPHSRNSITLTNLTPGTEYVVSIVALNG------REESPLLIGQQ 1444
E SGR V H+ +S + L P T Y + A N EES L Q
Sbjct: 1440 R-ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ 1498
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPA----------VTVRYYRITY----GET--GGN 1488
+ + P L V T TS+LI W PA +RY + Y G T G N
Sbjct: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558
Query: 1489 SP------------VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS-SKPIS 1535
+P ++ + P S + + L Y I + G+ P+S + +
Sbjct: 1559 NPGATWAELTSMYSMRNLSRP-SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617
Query: 1536 INYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRV-TTTPKNGPGPTKTKT 1589
+ P + V + V W P + + GY++ + G + KT
Sbjct: 1618 VGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKT 1677
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLV-QTAVTTIPAPTDLKFTQVTP 1645
+ + ++ L Y+VSV A N +G+ S P QT AP+ +KF+++T
Sbjct: 1678 LFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737
Query: 1646 TSLSAQWTP---PNVQLTGYRVRVTP-KEKTGPMKEINLAPDSSS---VVVSGLMVATKY 1698
TS++ W PN L GYR+ P G K + + +S + V L Y
Sbjct: 1738 TSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTY 1797
Query: 1699 EVSVYALKDTLTSRPAQGVVTTLENVSP-PRRARVTDATETTITISWRTKTE---TITGF 1754
+ A T V T +P P + + I I W + IT +
Sbjct: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRY 1857
Query: 1755 QVDAVPAN-GQTPIQ-RTIKPDVRSYTITG--LQPGTDYKIYLYTLNDNARSSP 1804
++A P++ G I + I +V SYT + L+PG Y + +ND +P
Sbjct: 1858 VIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
Score = 127 bits (320), Expect = 1e-28
Identities = 233/1060 (21%), Positives = 401/1060 (37%), Gaps = 152/1060 (14%)
Query: 600 QPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH--ISKYILRWRPKNSVGRWKEA 657
Q ++T+ GPV ++ + S + W P + ++ Y + W N
Sbjct: 886 QLVRTHEDVPGPVG-HLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTH 944
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+P Y + GL Y ++ ++ G +V+ ++T++ P
Sbjct: 945 YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS--------------ASTISSGVPP 990
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPST--- 771
P T+ ++ I S + + D ++S + VE ++ G+ ++L +
Sbjct: 991 ELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 1050
Query: 772 --ATSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD 824
A S+ +PDL P Y VN+ S + S + T Q AP + ++ +
Sbjct: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110
Query: 825 TSIVVRW---------SRPQAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPG 873
TS+ +RW P++ GY+I YS S T ++ + T+ DL+
Sbjct: 1111 TSLWLRWMPLPEMEYNGNPES--VGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEW 1168
Query: 874 VQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEVTDVKVTIMWTPPE 931
+Y + + A Q G R ++VPS P ++ + T + + W+
Sbjct: 1169 TEYRVQVQAFNAIGSGP---WSQTVVGRTR-ESVPSSGPTNVSALATTSSSMLVRWSEVP 1224
Query: 932 SA-----VTGYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFA---VSH 982
A V GY+V + + L ++ A++TGL V Y +V A +
Sbjct: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGD 1284
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPRAQ---ITGYRLT--VGL 1033
G S P ++T LD P + F ++V + W PP A I Y++T +
Sbjct: 1285 GSPSHPPILERT--LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342
Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTL----QP 1087
T + PS +Y L+P S Y + A KG E+ +A V T QP
Sbjct: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402
Query: 1088 GSSIPPYNTEVTETTIVITWTP-----APRIGFKLGVRPSQGGE---APREVTSDSGSIV 1139
S +V +++++W P +P + + R G V+ ++ S +
Sbjct: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462
Query: 1140 VSGLTPGVEYVYTIQVLRD-----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
V L P Y + ++ D E + P PT L + + T VL +
Sbjct: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL-IR 1521
Query: 1195 WERSTTPDITG--------YR--------------ITTTPTNGQQGNSLEEVVHADQSSC 1232
W+ I G YR I + S+ + + + S
Sbjct: 1522 WQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSL 1581
Query: 1233 T---FDNLSPGLEYNV--SVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMR 1284
T DNL+ Y + SVY + S P + + P P ++ +
Sbjct: 1582 TQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLD 1641
Query: 1285 VTWAPPP----SIDLTNFLVRYSPVKN---EEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
VTW PPP + D+ + + + + E V L ++ +N+V L NL T Y+VS
Sbjct: 1642 VTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA--ENSVKLKNLTGYTAYMVS 1699
Query: 1338 VSSVYEQHE---STPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR---ATITGYRI 1390
V++ + STP +G+ Q+ +P+ + FS++T S V W AP+ + GYR+
Sbjct: 1700 VAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRL 1759
Query: 1391 RHHP-EHFSGRPREDRVPHSRNS---ITLTNLTPGTEYVVSIVALN---GREESPLLIGQ 1443
+ P G + V NS + + +L G Y I A G E +
Sbjct: 1760 VYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTG 1819
Query: 1444 QSTVSDVPRDLEVVAATPTSLLISWDA----PAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
+ P + ++ +++ I W + RY G + +P
Sbjct: 1820 PGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKE 1879
Query: 1500 KSTATISG--LKPGVDYTITVYAVT----GRGDSPASSKP 1533
S+ T S LKPGV Y V AV G SP+ S P
Sbjct: 1880 VSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVP 1919
Score = 97.1 bits (240), Expect = 2e-19
Identities = 143/594 (24%), Positives = 233/594 (39%), Gaps = 66/594 (11%)
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESP--LLIGQQSTVSDVPRDLEVVAATPTSLL--ISW 1468
I+ T+++ Y G +E+ L++ ++ ++ P+D V+ T S++ ++
Sbjct: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
D P VT+RY G T G + + S IS G T T ++ G+
Sbjct: 522 D-PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH-ISQTWSGDIGTYTCRVISAGGNDS 579
Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTPKNGPGPT 1585
S+ + + + ++ V+ +I++ W +SP+ Y + + N P
Sbjct: 580 RSAH-LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTV 638
Query: 1586 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP------APTDLK 1639
+ P T +T++GL P Y + A N G+ Q T ++P P ++
Sbjct: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698
Query: 1640 FTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKEKTGPMKEINLA-PDSSSVVVSGLM 1693
+ T S+ QW PP N L GY +R + N+ D +++++ L+
Sbjct: 699 ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758
Query: 1694 VATKYEVSVYALKDT--------LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745
+ T YE+ V A +T QGV T PP TTI +W
Sbjct: 759 IWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTV-----PPGNVHAEATNSTTIRFTWN 813
Query: 1746 TKTETI-----TGFQVDA-VPANGQTPIQRTIKPDVRSYT----ITGLQPGTDY---KIY 1792
+ G+++ A P + T +P+ + ++GL+ T+Y +
Sbjct: 814 APSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLC 873
Query: 1793 LYTLNDNARSSPVVIDASTAIDAP-SNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYE 1848
T D RS+P ++ + P +L F SL VSWQ P + +TGY I +E
Sbjct: 874 FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWE 933
Query: 1849 KPGSPPREVVPRPRPGVT-EATITGLEPGTEYTIYVIALKN---NQKSEPLIGRKKTDEL 1904
+ V P VT E +TGL T YTI V A+ + Q S I EL
Sbjct: 934 EYNRTNTRVT-HYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPEL 992
Query: 1905 PQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 1958
P P NL I T+Q PGYD I Q VG+
Sbjct: 993 PG----PPTNLGISNIGPRSVTLQ-----FRPGYDGKTSISRWLVEAQVGVVGE 1037
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 148 bits (373), Expect = 7e-35
Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 29220 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 29278
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 29279 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 29328
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 29329 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 29385
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 29386 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 29445
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 29446 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 29505
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 29506 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 29557
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 29558 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 29616
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 29617 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 29674
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 29675 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 29733
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 29734 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 29793
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 29794 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 29853
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 29854 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 29911
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 29912 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 29971
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 29972 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 30031
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 30032 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 30091
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 30092 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 30143
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 30144 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 30202
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 30203 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 30261
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 30262 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 30318
Query: 1629 VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
T P + + VT +S+S W+ P ++TGY + ++
Sbjct: 30319 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 30378
Query: 1677 EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
++ V+GL+ +Y+ + A D + TS ++ VV + S P
Sbjct: 30379 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 30438
Query: 1732 VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
+ ++ ++T+ W + I G+ V+ +G + +++ K + + +TI GL
Sbjct: 30439 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 30497
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
T+Y+ ++ N+ S P
Sbjct: 30498 ATEYEFRVFAENETGLSRP 30516
Score = 140 bits (353), Expect = 1e-32
Identities = 320/1467 (21%), Positives = 549/1467 (37%), Gaps = 222/1467 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 19790 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 19846
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 19847 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 19891
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 19892 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 19948
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 19949 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 20008
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 20009 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 20066 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 20118
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 20119 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 20177
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 20293
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 20294 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 20353
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 20354 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 20412
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 20413 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 20465
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 20466 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 20515
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 20516 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 20575
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 20576 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 20635
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 20636 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 20695
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 20696 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 20755
Query: 1526 -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 20756 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 20815
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
+ + + I T ++V+++ +NP+G+ V V P P +
Sbjct: 20816 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 20873
Query: 1638 LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
L+ T +T S++ W P + ++T Y V +++ K + A + V+
Sbjct: 20874 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 20929
Query: 1691 GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
GL +Y V A + P + V E SPP + D T++T++++W
Sbjct: 20930 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 20989
Query: 1745 RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
ITG+ ++A + Q T+K + L G +Y + +N RS+
Sbjct: 20990 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 21047
Query: 1804 -----PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 1858
PV++ T + +LR + +Q G IK E P V+
Sbjct: 21048 PRESRPVIVKEQTML-PELDLRGI----------YQKLVIAKAGDNIKVEIP------VL 21090
Query: 1859 PRPRPGVT---------EATITGLEPGTEYTIYVI--ALKNNQKSEPLIGRKKTDELPQL 1907
RP+P VT + E TI I ++++ PL R E+ +
Sbjct: 21091 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 21150
Query: 1908 VTLPHPNLHGPEILDVPSTVQKTPFVT 1934
+T+ ++ GP + + FVT
Sbjct: 21151 ITIQVHDIPGPPTGPIKFDEVSSDFVT 21177
Score = 129 bits (323), Expect = 4e-29
Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 13776 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 13834
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 13881
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 13882 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 13941
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 13942 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 14001
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 14059
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 14060 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 14119
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 14120 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 14178
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 14179 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 14238
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 14239 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 14298
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 14299 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 14357
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 14358 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 14411
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 14412 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 14470
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 14471 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 14530
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 14590
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 14591 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 14648
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 14649 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 14708
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 14709 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 14768
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 14769 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 14828
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 14829 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 14888
Query: 1624 LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
V + AP VT S+ +W P + GY + T
Sbjct: 14889 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 14948
Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
+ ++ V GL+ Y V A + P T + +SPP
Sbjct: 14949 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 15008
Query: 1731 RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
RVTD + TTI + W I G+ VD + T K VR YT+ ++
Sbjct: 15009 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 15068
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
G DYK+ + +N P
Sbjct: 15069 GADYKLRVSAVNAAGEGPP 15087
Score = 128 bits (321), Expect = 7e-29
Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 13436 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 13491
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 13492 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 13551
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 13552 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 13611
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 13612 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 13670
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 13725
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 13726 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 13778
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 13779 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 13835
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 13836 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 13894
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 13895 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 13953
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
V K K + P I D I P PP PT ++G ++R+ W P
Sbjct: 13954 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 14010
Query: 1292 -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
+ ++++ +E V P+ +L L+ G EY V +V + E
Sbjct: 14011 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 14069
Query: 1347 --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
S P+ R+K S P ++ +IT N+ + W P + IT Y + G
Sbjct: 14070 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 14129
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
D T+T LT G+ YV + A N E +L T P
Sbjct: 14130 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 14188
Query: 1453 DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
L VV T + + W+ P ++ Y I E G V+ G ++ +
Sbjct: 14189 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 14248
Query: 1509 KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
G + V A G G ++ +SI T P + VTD I++ W P
Sbjct: 14249 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 14308
Query: 1565 ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
SP+ GY V P + + + + EG+ P EYV+ V A N G
Sbjct: 14309 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 14368
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
S+P + + + D K T T + + G ++ + + P+ ++
Sbjct: 14369 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 14420
Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
D V S + +S + L+ + R G+ T TLEN
Sbjct: 14421 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 14479
Query: 1724 VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
P + + +D T+++ ++W I + ++ A +T I + S+T
Sbjct: 14480 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 14539
Query: 1780 ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
+ L P +Y + +N ++ + D D P ++ T ++ ++
Sbjct: 14540 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 14599
Query: 1833 WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
W+PP ++I GYII+ G + + T GLE G EY V A
Sbjct: 14600 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 14659
Query: 1889 NQKSEP 1894
SEP
Sbjct: 14660 AGISEP 14665
Score = 127 bits (318), Expect = 2e-28
Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 18305 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 18363
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 18364 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 18423
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 18424 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 18481
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 18482 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 18541
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 18542 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 18600
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 18601 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 18659
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 18660 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 18717
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 18718 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 18774
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 18775 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 18833
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 18834 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 18892
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 18893 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 18946
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 18947 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 19006
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 19007 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 19065
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 19066 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 19115
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 19116 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 19173
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 19174 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 19233
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
+ TA Q E T GL+ +Y + + + +TAV P P+D
Sbjct: 19234 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 19282
Query: 1638 LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
P ++ A+ PP + L+ + +T K T PM ++ D +
Sbjct: 19283 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 19335
Query: 1687 V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
+ G+ +A + + L KD T+T+ + G + L+ PP
Sbjct: 19336 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 19395
Query: 1731 RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
++ +SW E IT + VD + Q + + S ++ L G
Sbjct: 19396 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 19455
Query: 1787 TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
+Y+ + N PV + A D P T + + VSW+PP
Sbjct: 19456 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 19515
Query: 1838 -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
+ ITGY++ EK + R + E T+ TGL+ GTEY V A+ +P
Sbjct: 19516 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 19573
Score = 125 bits (314), Expect = 5e-28
Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
N+ + W P S I+ Y + R K S+ RW A P + GL+ G YE
Sbjct: 20586 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 20644
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ + + G + S++V + + P ++ VT+ T S ++
Sbjct: 20645 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 20692
Query: 740 W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W ++G+ VE++ + GDE D TA + +PDL KY +
Sbjct: 20693 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 20750
Query: 793 ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
I++ G + ++ + + PD +D ++VVR R PI G +P
Sbjct: 20751 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 20807
Query: 849 VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
V + +NL AN ++ + + I ++ V+ E +S V
Sbjct: 20808 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 20861
Query: 908 ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
P P +L+ ++T VT+ W P S +T Y V+
Sbjct: 20862 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 20921
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
+ T+ +VTGLS G Y+F+V A + +P + K P +L ++ T ST
Sbjct: 20922 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 20980
Query: 1013 VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
V + W P+ ++ITGY + R+G + ++ + +RNL EYT ++
Sbjct: 20981 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 21038
Query: 1068 AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
A+ S ++ + +P + +VI P P +
Sbjct: 21039 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 21098
Query: 1115 FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+K G + Q E T+ S + ++ Y + E I +V
Sbjct: 21099 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 21158
Query: 1174 LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PPT + +T SW E I+ Y + T+ L V
Sbjct: 21159 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 21218
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
T L+ GLEY V I+ I A VP PP + T + D+M
Sbjct: 21219 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 21276
Query: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
++W P S + L + K + ++S + N + L G Y V +
Sbjct: 21277 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 21336
Query: 1342 YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
+S P + + +D P +IT ++ T+ W P T IT Y +
Sbjct: 21337 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 21396
Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
+ + N T++ LT Y ++A N I S SD
Sbjct: 21397 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 21452
Query: 1454 LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
+ V A + + + + +R+ +G P E++ G + T
Sbjct: 21453 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 21512
Query: 1512 VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
D++ + A T +P N + +D+P + VT+V
Sbjct: 21513 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 21571
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
+ W P + + Y V + T + T++ + L EY+ V
Sbjct: 21572 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 21630
Query: 1614 AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
A N G +PL V + P + + T +T S+ W P+ ++ Y
Sbjct: 21631 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 21690
Query: 1664 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
V K +K VSGL +YE + A S P+
Sbjct: 21691 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 21750
Query: 1719 TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 21751 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 21807
Query: 1774 DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
SYTITGL +YKI +Y +N P ++
Sbjct: 21808 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 21845
Score = 123 bits (308), Expect = 2e-27
Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 19484
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 19485 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 19544
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 19545 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 19604
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 19605 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 19664
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 19665 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 19723
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 19784 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 19841
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 19842 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 19898
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 19899 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 19953
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 19954 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 20010
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 20011 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 20061
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 20062 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 20118
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 20119 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 20178
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 20179 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 20238
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 20239 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 20298
Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 20299 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 20358
Query: 1623 PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
++ T I APT + L+ + + L + P K+ K
Sbjct: 20359 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 20416
Query: 1677 ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
+I P SS + + AT+ + Y + T ++ VT L+
Sbjct: 20417 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 20473
Query: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
PP +++ + T++W E + +T + + D++S +
Sbjct: 20474 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 20533
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
T L G +Y + +N + PV + +D P T N+ VSW+
Sbjct: 20534 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 20593
Query: 1835 PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
P + ITGY ++ + S + +TGL+ G+ Y V A
Sbjct: 20594 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 20648
Score = 122 bits (307), Expect = 3e-27
Identities = 286/1294 (22%), Positives = 482/1294 (37%), Gaps = 173/1294 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 27149
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 27150 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 27205
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 27206 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 27262
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 27263 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 27313
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 27314 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 27372
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 27373 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 27432
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 27433 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 27488
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 27489 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 27548
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 27549 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 27605
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 27606 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 27661
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 27662 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 27720
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 27721 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 27780
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 27781 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 27840
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 27841 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 27900
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
+ + + T+ GL P Y + A+N P +S ++ T +P +
Sbjct: 27901 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 27959
Query: 1638 ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
+K + Q P ++T ++ V +++ EI S+S+
Sbjct: 27960 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 28016
Query: 1688 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
V AT+ VY ++ S A+ + +P + R T+ T +T+ W
Sbjct: 28017 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 28073
Query: 1745 RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
IT + ++ + K + +SYT L G +Y+ + +N
Sbjct: 28074 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 28133
Query: 1799 ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
S PVV T DAP T NS+ ++W P + I YI+ + EK
Sbjct: 28134 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 28193
Query: 1850 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT 1909
+ +V+ + T +TGL G EY +V+A +N P G + + + V
Sbjct: 28194 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVN 28252
Query: 1910 LPHPNLHGPEILDVPSTVQKTPFV--THPGYDTG 1941
P P P ++ V T + T + + P +D G
Sbjct: 28253 PPGP----PTVVKVTDTSKTTVSLEWSKPVFDGG 28282
Score = 116 bits (291), Expect = 2e-25
Identities = 282/1346 (20%), Positives = 481/1346 (35%), Gaps = 213/1346 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 24153
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 24154 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 24200
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 24201 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 24256
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 24257 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 24316
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 24317 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 24375
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 24428
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 24429 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 24487
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 24605
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 24606 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 24659
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 24660 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 24719
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 24779 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 24837
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 24838 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897
Query: 1360 ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 25017
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 25018 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 25065
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 25066 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 25121
Query: 1566 SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 25122 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 25178
Query: 1613 YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
+N SG V V P AP +L +V S++ W PP ++T Y +
Sbjct: 25179 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 25235
Query: 1668 PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
K +T + + + + L Y V A + PA+ V E
Sbjct: 25236 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 25295
Query: 1724 VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
PP R + D T T TI W K E+ ITG+ V+ + G +
Sbjct: 25296 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 25353
Query: 1779 TITGLQPGTDYKIYLYTLNDNARSSP 1804
TI+GL G +Y + +N+ RS P
Sbjct: 25354 TISGLTAGEEYVFRVAAVNEKGRSDP 25379
Score = 116 bits (291), Expect = 2e-25
Identities = 149/690 (21%), Positives = 263/690 (38%), Gaps = 70/690 (10%)
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
PP ++ I ++ ++W PP L+ ++V + +S S + +
Sbjct: 29834 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 29892
Query: 1325 LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
T L G EYV V++ Y Q E R + P + D++ + T+
Sbjct: 29893 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 29951
Query: 1378 WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
W P + +TGY + R ++VP + T LT G EY + A+N
Sbjct: 29952 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 30011
Query: 1434 R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
R P++ P++ V T TS+ ++W P V Y I
Sbjct: 30012 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 30071
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ + + T P T++ L G +Y V A G + P ++ +
Sbjct: 30072 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 30131
Query: 1543 DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
+ P ++ + I V+ + + P+ G + + K G +K +T
Sbjct: 30132 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 30190
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
E+ I+ + +N G+ ++ V P + L++ + S+ W
Sbjct: 30191 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 30250
Query: 1654 PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 30251 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 30307
Query: 1708 TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
S+P ++ VT ++PP V D T++++++SW R K + +TG+ ++
Sbjct: 30308 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 30367
Query: 1758 AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
+ ++ K + + YT+TGL P +Y+ + ND + S PVV D
Sbjct: 30368 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 30426
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 30427 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 30486
Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ TI GL TEY V A S P
Sbjct: 30487 DKQFTIGGLLEATEYEFRVFAENETGLSRP 30516
Score = 113 bits (283), Expect = 2e-24
Identities = 299/1397 (21%), Positives = 486/1397 (34%), Gaps = 195/1397 (13%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 24772 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 24826
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 24827 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 24884
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 24885 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 24943
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 24944 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 24997
Query: 905 DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 24998 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 25057
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
L G+ VT L Y F++ A++ +P T AQ+ +
Sbjct: 25058 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 25106
Query: 997 --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 25107 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 25163
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 25164 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 25223
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 25224 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 25339
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
++ ++ +V + T L+ G EY V V + S P + +I + P
Sbjct: 25340 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 25396
Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
+L F P V + V + + V LSI
Sbjct: 25397 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 25456
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
+ V GT + +S + + G P ID +++ +S T+ W
Sbjct: 25457 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 25508
Query: 1379 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
P I+ Y I E S +R SI + LT G+EY + A N
Sbjct: 25509 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 25567
Query: 1434 -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
E S ++ + P +VV AT +++L++W P V Y + Y E
Sbjct: 25568 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 25627
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
+ + + + +SGL G+ Y VYA + G G S +P+ R
Sbjct: 25628 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 25685
Query: 1543 DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
D P Q +VT++ S+S+KW + +TGY V K +T
Sbjct: 25686 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 25745
Query: 1599 IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
+ L Y V+A+N PS + P +V+ V D+KF V +
Sbjct: 25746 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 25804
Query: 1651 QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
+ N + G + V K G E ++ D+ +++ + V L
Sbjct: 25805 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 25864
Query: 1706 KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
K+ +R L+ PP + T ++SW E G +D V
Sbjct: 25865 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 25923
Query: 1763 GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
+ + TI + + S +T L G +Y + +N P+ +D T
Sbjct: 25924 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 25983
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
P++L + T S+ + W P + I+GYII+ + S V +
Sbjct: 25984 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 26043
Query: 1870 ITGLEPGTEYTIYVIA-----LKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 1924
TGL G EY V A L ++ PLI + V LP P P+I+D
Sbjct: 26044 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP------VFLPSPP-SKPKIVDSG 26096
Query: 1925 STVQKTPFVTHPGYDTG 1941
T +V P +D G
Sbjct: 26097 KTTITIAWV-KPLFDGG 26112
Score = 112 bits (281), Expect = 3e-24
Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 20473 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 20527
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 20528 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 20574
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 20575 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 20634
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 20635 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 20694
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 20695 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 20753
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 20754 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 20813
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 20814 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 20870
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 20871 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 20929
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 20930 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 20988
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 20989 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 21047
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 21048 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 21104
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 21105 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 21164
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 21165 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 21223
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 21224 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 21283
Query: 1383 AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 21284 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 21343
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 21344 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 21400
Query: 1492 QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ + T+SGL Y V A G SP S +I R +++ P
Sbjct: 21401 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 21460
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 21461 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 21513
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
+ ++ A NP G ++ + V P P + L T+VT
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 21573
Query: 1650 AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
W PP ++ Y V+ K +T + N+A + + + V+ L+ +Y
Sbjct: 21574 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 21630
Query: 1699 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
V+ Y + + L S P V PP+ VT T+ ++ + W ++
Sbjct: 21631 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 21689
Query: 1759 VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
+ QR IK + ++ Y ++GL G +Y+ + N S+P
Sbjct: 21690 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 21749
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
D P N R L T+ +S+ ++W P + ITGY+++ P ++V P
Sbjct: 21750 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 21809
Query: 1863 P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
T TITGL EY I + A+ + EP +
Sbjct: 21810 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 21844
Score = 110 bits (275), Expect = 2e-23
Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
N V P P+ S E+T V+SW D G ++ + E+ + + + +
Sbjct: 16907 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 16960
Query: 769 PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
P T+ T+ + LL G+ YI N+Y IS+ + + + PDAP P V
Sbjct: 16961 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 17020
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
+V S +V W++P PIT Y + ++ + + DL G
Sbjct: 17021 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 17080
Query: 875 QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
QY + A E P + P + + ++ T V + W PP
Sbjct: 17081 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 17140
Query: 932 -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
S + GY V+ V + P S T +VTGL G TY F+V AV+ ES P
Sbjct: 17141 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 17200
Query: 989 LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
+ +L+ P + N + R A I G ++T R P
Sbjct: 17201 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 17260
Query: 1040 RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
+ +V P SK +RN SL + V +PG PP + E
Sbjct: 17261 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 17317
Query: 1098 VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
V+E + +TW G + + R + +P TS S L G
Sbjct: 17318 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 17377
Query: 1148 EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
+Y++ +V + Q P V K + PL PP +LH + D +++ W +
Sbjct: 17378 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 17434
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
R ITGY + Q + V + + C L G Y V ++
Sbjct: 17435 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 17489
Query: 1257 VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
+ + DT IP VPP +L I T+R + P P+ T
Sbjct: 17490 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 17546
Query: 1301 RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
S +K +E + + S + L T EY ++VS+ + T LD
Sbjct: 17547 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 17602
Query: 1360 ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
PTG I+ D+T T+ W P+ I + E R V S +S T
Sbjct: 17603 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 17662
Query: 1415 --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+ +L G EYV + A N + +P + + + P V T + +
Sbjct: 17663 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 17722
Query: 1467 SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
SW P + YY TG V + + K T GL G Y V+A
Sbjct: 17723 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 17780
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S S I I P ++ D + + W SP+ GY V
Sbjct: 17781 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 17840
Query: 1575 TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
PG + D Q + GL EY + A N GE +P L ++
Sbjct: 17841 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 17897
Query: 1629 VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
+ I P +++ VT + +++ RV+ P+ K G + K +
Sbjct: 17898 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 17955
Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
+L D V + + A + + Y + +S AQG +V L+ P + +VT+ T
Sbjct: 17956 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 18014
Query: 1737 ETTITISWRTKTET----ITGFQVD 1757
+ TISW + IT F V+
Sbjct: 18015 KENCTISWENPLDNGGSEITNFIVE 18039
Score = 110 bits (274), Expect = 2e-23
Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
+T++T S +++W D Y + D + L ST N L+P +
Sbjct: 13792 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 13851
Query: 785 KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
+YI N+Y + E + S I + Q P P + ++ + W P
Sbjct: 13852 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 13911
Query: 836 APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
+PITGY + P + +P + + L +Y + A + +S
Sbjct: 13912 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 13971
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
T ++ ++ P P+ +D V V + WT PE + + Y ++++
Sbjct: 13972 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 14026
Query: 946 LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
+ +P +++ + GL G Y F+V AV+ ES+P L ++
Sbjct: 14027 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 14083
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
P L+ +N T +T ++WT P + IT Y + RR + + +K
Sbjct: 14084 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 14143
Query: 1053 LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
+ L S Y + A ++S A FTT PG PPY V + T
Sbjct: 14144 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 14198
Query: 1103 -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
+ + W P G + LG R + G+ + V+ + G E
Sbjct: 14199 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 14254
Query: 1150 VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
+ ++ + + + + +P SPP +LH+ D G + ++W E++
Sbjct: 14255 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 14311
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I GY + P ++ + D + + P EY + V V S P
Sbjct: 14312 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 14371
Query: 1259 --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
IS+ ++ P P DL +I P R P S V+ S
Sbjct: 14372 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 14431
Query: 1305 ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
+KN+ A L + S A + L N L ++V +
Sbjct: 14432 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 14477
Query: 1356 TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
GL P I SDIT +S + W P G I H+ R +P ++
Sbjct: 14478 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 14535
Query: 1411 NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S T+ +L P EY + A+N G E ++P++ D P D+EV T +
Sbjct: 14536 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 14595
Query: 1464 LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
+ I+W P + Y +I GE E VP T T GL+ G +Y
Sbjct: 14596 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 14652
Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
V A G S S ID P + T ++ D SIS +
Sbjct: 14653 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 14712
Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
W+ + + + K P + G Q E
Sbjct: 14713 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 14768
Query: 1600 -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
+ L+P + + +N G ++ P + + T P + F + TS+ +W PP
Sbjct: 14769 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 14827
Query: 1656 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
++ Y + K K PDS +VV+ + KY V+ Y +
Sbjct: 14828 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 14877
Query: 1708 TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
+R G V L P P + V D T ++ + W + I G+
Sbjct: 14878 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 14937
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
++ N + + +++ +++ + GL G Y + N + SP D T
Sbjct: 14938 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 14995
Query: 1812 AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
A D P R T+ ++ + W+PP I GY + + G+
Sbjct: 14996 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 15055
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V + T+ + G +Y + V A+ + P
Sbjct: 15056 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 15087
Score = 110 bits (274), Expect = 2e-23
Identities = 298/1381 (21%), Positives = 508/1381 (36%), Gaps = 185/1381 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 21563 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 21680
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 21681 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 21739
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 21796
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 21797 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 21856
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 21857 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 21907
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 21908 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 21967
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 21968 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 22024
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 22025 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 22082
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 22083 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 22139
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 22140 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 22193
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 22194 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 22251
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 22252 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 22310
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 22311 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 22369
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 22370 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 22429
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 22430 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 22489
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
T + GL Y V A+N +G S+P T T D S
Sbjct: 22490 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 22544
Query: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
+ ++ V G +V P+ I +++ + + AT V
Sbjct: 22545 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 22604
Query: 1702 ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
+ K+ R V L+ PP ++ T T++W+ +
Sbjct: 22605 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 22664
Query: 1751 ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
++ + +T + + +V+ S +T L G +Y + Y + +
Sbjct: 22665 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 22724
Query: 1802 SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
S PVV + DAP T +S++V W+ P + I GY++ K +K G
Sbjct: 22725 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 22784
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 1915
R G +TGL +Y V A SEP + PN
Sbjct: 22785 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN- 22842
Query: 1916 HGPEILDVPSTVQKTPFV--THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPP 1973
P+++D+ + + F+ + P YD G IQ SVG+ + TPP
Sbjct: 22843 -NPKVIDI---TRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE--------WTMCTPP 22890
Query: 1974 T 1974
T
Sbjct: 22891 T 22891
Score = 109 bits (273), Expect = 3e-23
Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 13045 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 13104
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 13105 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 13163
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 13164 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 13223
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 13224 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 13283
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 13284 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 13341
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 13342 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 13400
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 13401 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 13460
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 13461 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 13515
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 13516 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 13633
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 13634 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 13687
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 13688 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 13744
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 13745 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 13804
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 13805 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 13857
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 13858 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 13917
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
V + + T ++GL +Y V A+N +G +P T I
Sbjct: 13918 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 13977
Query: 1633 PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
P D + P TS+ WT P ++ Y + + KTG + + +A
Sbjct: 13978 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 14034
Query: 1682 P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
++ ++ GLM +Y V A+ S P++ V E + SPPR V +
Sbjct: 14035 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 14094
Query: 1735 ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
T+ T + W + IT + V+ V G + T+K T+T L G+
Sbjct: 14095 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 14152
Query: 1789 YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
Y + N +S S + D T P L + T + + W+PP+
Sbjct: 14153 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 14208
Score = 109 bits (273), Expect = 3e-23
Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)
Query: 692 VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
VTRFD S +T +G T F SP + ++ E+ S +SW
Sbjct: 25168 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 25223
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ ++ + VE E Y + + T T+ I +L G Y V +E G
Sbjct: 25224 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280
Query: 799 QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
L T++ PP P T+ V + ++W +P++ ITGY V +
Sbjct: 25281 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 25337
Query: 851 GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
GS + T+S L G +Y + AV E S P VI ++ P
Sbjct: 25338 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 25395
Query: 905 DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
+V P V+ + +K+ + + A +R D GQ L ++ +
Sbjct: 25396 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 25444
Query: 960 TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
+ VT LS V Y + S G + P+T + P ++ + ++
Sbjct: 25445 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 25504
Query: 1014 LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
+ W PP QI+ Y V + V +V++ ++ L SEY +
Sbjct: 25505 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 25562
Query: 1068 AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
A ES + PG P T++T+++TW IG+
Sbjct: 25563 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 25622
Query: 1117 LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
L + +A + + +D+ + VSGL G+ Y VY + G+ +
Sbjct: 25623 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 25681
Query: 1171 VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
P PP TN+ ++ + D G + ER PD G + TN
Sbjct: 25682 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 25739
Query: 1216 QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
Q+ + DQ + D++S E + VKDD E V D
Sbjct: 25740 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 25798
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
I+ + G ++WA I++ E+ A I +DN
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 25844
Query: 1323 VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
+LT +YV+++ +V + + K G P G ++ + +TA ++
Sbjct: 25845 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 25902
Query: 1377 HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
W P+ A I Y + + H + E + S +T L G EY+ + +
Sbjct: 25903 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 25960
Query: 1432 NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
N E + TV P LE+ + T S+ + W P + Y I
Sbjct: 25961 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 26020
Query: 1482 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
E V+ P +GL+ G +Y VYA G S P+ + P+ I
Sbjct: 26021 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 26079
Query: 1541 EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
+ PS+ ++ D +I++ W+ +P+TGY V K+ KT
Sbjct: 26080 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 26138
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
TE TI GL EYV V + N PS S P + P ++++ T +
Sbjct: 26139 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 26198
Query: 1645 PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
S T P +R R P +T + + S ++ + +
Sbjct: 26199 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 26252
Query: 1696 TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
KY +++ ++ L++ VV L+ PP V D T+ + +SW +
Sbjct: 26253 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 26309
Query: 1752 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
+ ++ A+ + + T + SY +T LQ G Y + N+ P
Sbjct: 26310 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 26369
Query: 1812 AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
I P L + + +S+ ++W P +RI Y+++ + G + V
Sbjct: 26370 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 26427
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
T ++GL +EY V A S+P
Sbjct: 26428 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 26458
Score = 105 bits (262), Expect = 5e-22
Identities = 346/1650 (20%), Positives = 609/1650 (36%), Gaps = 262/1650 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 15215 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 15272
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 15273 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 15319
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 15320 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 15379
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 15380 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 15435
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 15436 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 15496 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 15552
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 15553 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 15612
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 15613 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 15668
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 15669 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 15728
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 15729 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 15784
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 15785 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 15844
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 15845 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 15903
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 15904 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 15962
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 15963 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 16022
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 16023 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 16082
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 16083 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 16142
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 16143 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 16202
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 16203 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 16259
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
N KT ++ P + TI L EYV + AQN G +PL T +
Sbjct: 16260 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315
Query: 1632 IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
+P AP + VT S++ W P +TGY + + K+ T K +N P +
Sbjct: 16316 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 16373
Query: 1686 -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
S V+GL+ + Y+ VYA+ +L S PA T + ++PP +V
Sbjct: 16374 MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 16429
Query: 1733 TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
TD T+++ + W + +TG+ V+ G+ ++ +VR +TGL+ G
Sbjct: 16430 TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 16488
Query: 1787 TDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1842
YK + +N P VI+ + +P +L+ A+ + ++V RI
Sbjct: 16489 AFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGVIRIIA 16546
Query: 1843 YIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE----PLI 1896
Y+ G PP V R EATI T + +KN Q+S L+
Sbjct: 16547 YV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQGVYSLL 16596
Query: 1897 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----PGTSGQ 1952
+ + E + + + ++LDVP V TPF+ H T +L P G
Sbjct: 16597 AKNEAGERKKTIIV--------DVLDVPGPV-GTPFLAH--NLTNESCKLTWFSPEDDGG 16645
Query: 1953 QPSVGQQMIFEEHGFRRTTPPTTATPIRH--------RPRPYPPNVGEEIQIGHIPREDV 2004
P + +I + RR P T T R + + Y + E IG P +
Sbjct: 16646 SP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 16704
Query: 2005 DYHLYPHGPGLNPNASTGQEALSQT----TISWAP--FQDTSE---YIISCHPVGTDEEP 2055
L P P E T T++W P + SE Y++ +GT++
Sbjct: 16705 SEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH 16764
Query: 2056 LQFRVPGTSTSATLTGLTRGATYNIIVEAL 2085
S T+ GL G TY V A+
Sbjct: 16765 KVTNDNLLSRKYTVKGLKEGDTYEYRVSAV 16794
Score = 105 bits (261), Expect = 7e-22
Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 16229 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 16288
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 16289 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 16348
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 16349 TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 16406
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 16407 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 16466
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 16467 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 16526
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 16527 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 16580
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 16581 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 16640
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 16641 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 16700
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 16701 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 16759
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 16760 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 16816
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
PPT +R T R + P P + S K+E DV E +
Sbjct: 16817 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 16867
Query: 1315 SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
+P+ A+ G VV +S + + + G P G + F ++T
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 16925
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
+ + W P G +I ++ ++ +P ++ + ++ L G +Y+
Sbjct: 16926 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 16984
Query: 1427 SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
I A N S L+ V D P V T S L++W+ P
Sbjct: 16985 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 17044
Query: 1472 -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
++ R+ R+T P +F VP L G Y V A
Sbjct: 17045 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 17092
Query: 1523 GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
G GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 17093 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 17149
Query: 1576 TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
K G + P+ +T+ + GL+ Y V A N +GES P +
Sbjct: 17150 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 17203
Query: 1633 PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
P P +K P L A G +R++ P K KE AP +
Sbjct: 17204 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 17263
Query: 1686 SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
+ V+ V +K E+ +Y+L ++ S+ V L+ PPR V++
Sbjct: 17264 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 17321
Query: 1736 TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
+ + ++W+ + IT + V+ V + +P+ T K +S+ L G Y
Sbjct: 17322 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 17379
Query: 1790 KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
+ N R V +D P +L + + + W P +
Sbjct: 17380 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 17439
Query: 1839 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
ITGY+++Y++ G+ ++ + E +TGL+ G Y V K+E ++G
Sbjct: 17440 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 17489
Score = 102 bits (255), Expect = 3e-21
Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 16635 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 16693
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 16694 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 16741
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 16742 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 16801
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 16802 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 16862 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 16919
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 16920 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 16975
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 16976 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 17035
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 17036 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 17095
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 17096 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 17153
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 17154 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 17213
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 17214 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 17272
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 17273 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 17318
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 17319 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 17377
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 17378 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 17436
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 17437 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 17494
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 17495 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 17546
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 17547 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 17598
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 17599 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 17655
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
+G +T++ I LQ EYV V A+N G PL T + P+P T +
Sbjct: 17656 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 17715
Query: 1644 TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
T + + WT P +TGY + +E TG +N P + V+GL Y
Sbjct: 17716 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 17773
Query: 1699 EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
E V+A S+P+ ++ PP ++ D + T + W TK
Sbjct: 17774 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 17832
Query: 1749 ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
I G+ V+ G R K ++ ++ + GL G +Y+ + N P
Sbjct: 17833 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 17890
Score = 102 bits (255), Expect = 3e-21
Identities = 255/1289 (19%), Positives = 459/1289 (35%), Gaps = 229/1289 (17%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 23918 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 23975
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 24035
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 24036 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 24086
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 24087 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 24146
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 24147 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 24205
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 24206 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 24261
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 24262 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 24320
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 24321 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 24346
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 24347 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 24392
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 24393 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 24415
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 24416 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 24471
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 24472 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 24531
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 24532 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 24586
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 24587 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 24646
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 24647 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 24706
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 24707 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 24766
Query: 1605 TV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
V +Y++ + N G + V P P + LK T VT W
Sbjct: 24767 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 24824
Query: 1654 PPNVQLTGYRVR--VTPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYA 1704
PP +Q G + + K +T + +++ + + V+ L+ +Y V+ Y
Sbjct: 24825 PP-LQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 24883
Query: 1705 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVP 1760
+ + L S P + PP V+ T+ ++ ++W + I G+ ++
Sbjct: 24884 IGEPLESGPVT-ACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD 24942
Query: 1761 ANG--QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDAST 1811
G T + D+R +TGL G Y+ + N P DA
Sbjct: 24943 KEGVRWTKCNKKTLTDLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY 25001
Query: 1812 AIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV-- 1865
PSN + T+ +S+ ++W P A + GY+++ K + P G+
Sbjct: 25002 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQG 25060
Query: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ T+T L+ TEY + A+ + EP
Sbjct: 25061 KQFTVTKLKENTEYNFRICAINSEGVGEP 25089
Score = 102 bits (254), Expect = 4e-21
Identities = 337/1641 (20%), Positives = 581/1641 (35%), Gaps = 234/1641 (14%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 23513 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 23571
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 23572 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 23620
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 23621 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 23680
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 23681 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 23737
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 23738 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 23797
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 23798 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 23850
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 23851 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 23907
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 23908 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 23965
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 23966 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 24024
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 24025 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 24084
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 24085 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 24139
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 24140 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 24199
Query: 1258 PIS--DTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEED 1310
P+ D + A PP P + T++ + + W P + ++V P K E
Sbjct: 24200 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEK 24258
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
+ ++ S NAVV T L G EY V + E+ G P + +
Sbjct: 24259 WSIVAESKVCNAVV-TGLSSGQEYQFRVKAYNEK------------GKSDPRVLGVP-VI 24304
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPE-----HFSGRPR------EDRVPHSRNSITLTNLT 1419
A T+ + + Y I+ + GRPR +D P + + T
Sbjct: 24305 AKDLTIQ-PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEET 24363
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVA---------------ATPTSL 1464
T V+ I N + + ++ +L V+ + +
Sbjct: 24364 -ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 24422
Query: 1465 LISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
+ISW+ PA T + Y + +T + + +++T I+ LK G +Y ++A
Sbjct: 24423 VISWEPPAYTGGCQISNYIVEKRDTT-TTTWHMVSATVARTTIKITKLKTGTEYQFRIFA 24481
Query: 1521 VTGRGDS-PASSKPISINYR-TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S P SK + + Y E P VT + + + V+W + + GY +
Sbjct: 24482 ENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHL 24541
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
KN K T+ GL +EY V A+N G +P +
Sbjct: 24542 EQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 24601
Query: 1635 PTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSS 1686
P D + +T +++ +W P ++TGY V MK +
Sbjct: 24602 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 24661
Query: 1687 VVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR--------VTDA 1735
VSGL+ +YE V A S P+ G +T + + P + V A
Sbjct: 24662 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 24721
Query: 1736 TET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYL 1793
ET + R K + D +T + IK ++ T+ TD Y+
Sbjct: 24722 GETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780
Query: 1794 YTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARITGYIIK 1846
L++ +S P+ + P L+ T ++W PP A I+ YII+
Sbjct: 24781 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 24840
Query: 1847 YEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQ 1906
+ V + +T L PG EY V+A+ EPL + P
Sbjct: 24841 KRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL------ESGPV 24893
Query: 1907 LVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHG 1966
P+ P +V + + + VT G ++ G ++ ++ G
Sbjct: 24894 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR--------DKEG 24945
Query: 1967 FRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH----LYPHGP 2013
R T T T +R R Y V E +G V Y LYP GP
Sbjct: 24946 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGP 25005
Query: 2014 GLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRVPG-TSTSA 2067
NP + + S +++W+ P D Y++ DE G
Sbjct: 25006 PSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQF 25063
Query: 2068 TLTGLTRGATYNIIVEALKDQ 2088
T+T L YN + A+ +
Sbjct: 25064 TVTKLKENTEYNFRICAINSE 25084
Score = 101 bits (252), Expect = 7e-21
Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 28166 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 28224
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 28225 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 28272
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 28273 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 28332
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 28333 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 28392
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 28393 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 28451
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 28452 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 28507
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 28508 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 28566
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 28567 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 28624
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 28625 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 28679
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 28680 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 28739
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 28740 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 28799
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 28800 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 28856
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 28857 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 28915
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 28973
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 28974 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 29031
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 29032 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 29091
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 29092 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 29148
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 29149 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 29196
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
+ YVV+ V A N G ES+P+V TIP+P + T +
Sbjct: 29197 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 29256
Query: 1649 SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
QWT P +++ Y V K + ++ + D + + V+ LM Y+
Sbjct: 29257 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 29313
Query: 1701 SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
V A+ S P A ++ E PP RV D T+ +I+++W
Sbjct: 29314 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 29362
Score = 101 bits (251), Expect = 1e-20
Identities = 277/1345 (20%), Positives = 482/1345 (35%), Gaps = 189/1345 (14%)
Query: 692 VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
V R+D +T T ++ T + +P + VTEIT S ++W +
Sbjct: 23003 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 23062
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
+ + VE E Y + + S I L G Y V +E G
Sbjct: 23063 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 23119
Query: 803 LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
+ + P P TVD V S+ + W++P+ I Y ++ +E
Sbjct: 23120 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 23178
Query: 860 ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
E A +++L G +Y + AV E S P +VI+ + S
Sbjct: 23179 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 23238
Query: 905 DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
+V +DL+ +EV K TI WT D +P+ Q I+
Sbjct: 23239 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 23281
Query: 962 AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
++T LS T+ Y A G+++ + K D P ++F + + ++
Sbjct: 23282 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 23341
Query: 1015 VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
+ W PP QIT Y + T + + + + L+ +EY + A
Sbjct: 23342 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 23401
Query: 1071 --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
G ES + +PG P+ T +++ ++VI W +P IG+ L
Sbjct: 23402 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 23461
Query: 1120 RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
+ + + + D+ L G+EY + + V + + + +
Sbjct: 23462 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 23520
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
P P + ++ N +T+ W + ITGY + P S V+
Sbjct: 23521 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 23576
Query: 1226 HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
++ T L+ Y V K + PI+ + +P + P D
Sbjct: 23577 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 23633
Query: 1273 LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
N G +T R V P P+I+ K E+ A I +D +L
Sbjct: 23634 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 23686
Query: 1326 -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
+ G +Y++ S+V +S P+ + P G + + +T+ ++ W +P
Sbjct: 23687 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 23744
Query: 1384 TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR----- 1434
G I H+ + + R V NS+ +T L G EYV I+A+N
Sbjct: 23745 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 23804
Query: 1435 -EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
E +P+L+ + P+ LEV S+ + W+ P I Y E S ++
Sbjct: 23805 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 23864
Query: 1493 EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
+ T ++GL +Y V A G S P ++ Y+ +
Sbjct: 23865 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 23922
Query: 1545 PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG-PTKTKTAGPDQTEMTI 1599
P+ + D NSI++ W S + GY V + T G T I
Sbjct: 23923 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 23982
Query: 1600 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
L EY + V A N G + T+V P D + L ++ V
Sbjct: 23983 SKLTEHQEYKIRVCALNKVGLGEA---TSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 24037
Query: 1660 TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
G R+ K P EI + + + V + + T+ + + L
Sbjct: 24038 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 24097
Query: 1706 KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
+++ S+ A V L+ PP+ V + + + + W + + +D +
Sbjct: 24098 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 24157
Query: 1762 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
+ + K S+ + L G Y + N+ PV +DA A + PS
Sbjct: 24158 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 24217
Query: 1818 --NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
L ++ T SL+ W+ P +R+ GY+++ + G+ +V + V A +T
Sbjct: 24218 KVTLTDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVT 24273
Query: 1872 GLEPGTEYTIYVIALKNNQKSEPLI 1896
GL G EY V A KS+P +
Sbjct: 24274 GLSSGQEYQFRVKAYNEKGKSDPRV 24298
Score = 98.6 bits (244), Expect = 6e-20
Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 25278 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 25335
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 25336 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 25386
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 25387 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 25443
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 25444 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 25500
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 25501 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 25560
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 25561 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 25614
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 25615 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 25673
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 25674 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 25731
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 25732 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 25782
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 25783 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 25839
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 25840 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 25898
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 25899 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 25956
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 25957 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 26016
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 26017 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 26075
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 26076 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 26133
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 26134 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 26189
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 26245
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 26246 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 26300
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 26301 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 26359
Query: 1621 SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
P +T P+P + L T ++ S+S W P ++ Y V K +
Sbjct: 26360 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 26419
Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
+K S+ VVSGL ++Y V+A S P + ++ L E + PP
Sbjct: 26420 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 26477
Query: 1729 ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
R + I IS + + F + N ++
Sbjct: 26478 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 26537
Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
++ D Y IT K ++ + VV+D P + + T S
Sbjct: 26538 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 26586
Query: 1829 LLVSWQPPR----ARITGYII 1845
+ + W+PP+ +++T YI+
Sbjct: 26587 VTLKWEPPKYDGGSQVTNYIL 26607
Score = 98.2 bits (243), Expect = 8e-20
Identities = 256/1304 (19%), Positives = 463/1304 (35%), Gaps = 171/1304 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 19506 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 19565
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 19566 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 19613
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 19614 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 19671
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 19672 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 19723
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 19784 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 19835
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 19836 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 19894
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 19895 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 19952
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 19953 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 20012
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 20013 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 20073 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 20130
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 20131 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 20188
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 20189 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 20246
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 20247 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 20306
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 20307 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 20362
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 20363 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 20419
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 20420 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 20479
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 20480 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 20539
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTTI-----PAPTDL-KFTQVTPTSLSAQWTPP--- 1655
EY+ V A N G+ +P+ V + P P + + + VT + + W P
Sbjct: 20540 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 20598
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++TGY V K+ ++ I V+GL + YE V A P+
Sbjct: 20599 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 20658
Query: 1715 QGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1765
+ + L PP VTD T+ + +++W ITG+ V+ +
Sbjct: 20659 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEA 20718
Query: 1766 PIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
I+ T +R + + LQ Y + +ND P VI
Sbjct: 20719 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 20762
Score = 97.4 bits (241), Expect = 1e-19
Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
T +VT L G Y F+V V+ +PL + LD PT+L+ + T ++
Sbjct: 25940 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 25999
Query: 1014 LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
+ W+ P + +I+GY + RR + V V+K P+ +L+ S
Sbjct: 26000 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 26053
Query: 1061 EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
EY V G ++ SP P P + +TTI I W A
Sbjct: 26054 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 26113
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
P G+ + + S + + S G+ +SGLT G EYV+ ++ + D +
Sbjct: 26114 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 26173
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
P + K P ++ E V +TV + P++ + + P +
Sbjct: 26174 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 26228
Query: 1218 GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + + ++S T +N + +Y +++ V S+ + ++ PPT++
Sbjct: 26229 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 26286
Query: 1276 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
++ ++ ++W P + +PVKN E + +S ++N + +T
Sbjct: 26287 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 26339
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
NL G Y VS E P ++ + P + + I+ +S ++ W+ P
Sbjct: 26340 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 26399
Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
G RI H+ + +++ V + T ++ L +EY + A N S
Sbjct: 26400 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 26458
Query: 1438 -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
P+LI +Q ++ P V A + D P ++T G
Sbjct: 26459 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 26515
Query: 1488 N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
F + TI+ LK V Y +T S + I+I +D+P
Sbjct: 26516 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 26571
Query: 1547 Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
+ ++D+ + S+++KW P S VT Y + + T+ +A +T M
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 26630
Query: 1599 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
+ L EY + A+N G S + VT T P P + T VT S++ W
Sbjct: 26631 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 26690
Query: 1653 TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
P + GY + + + K L ++ V+ + YE VYA
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 26750
Query: 1709 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
+P+ V ++ PPR R+TD ++ ++++SW+ ITG+ V+ +P
Sbjct: 26751 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 26810
Query: 1761 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
T T + + + I+GL + Y+ ++ N + + V+ T ID+
Sbjct: 26811 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 26866
Score = 96.3 bits (238), Expect = 3e-19
Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 13498 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 13556
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 13557 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 13616
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 13617 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 13676
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 13677 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 13736
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 13737 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 13795
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 13796 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 13855
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 13856 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 13915
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 13916 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 13974
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 13975 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 14031
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 14032 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 14091
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 14092 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 14150
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 14210
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 14211 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 14270
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 14271 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 14318
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 14319 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 14374
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 14375 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14434
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
M + + +E SV A +N G + + V +P P D+K + +T +
Sbjct: 14435 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 14494
Query: 1647 SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
S W PP T V + + G I + + S V L+ +Y V
Sbjct: 14495 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 14554
Query: 1704 ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
A+ ++ G L+N PP V + T +TI+W+
Sbjct: 14555 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 14609
Query: 1750 TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
I G+ ++ + A G+ +R + + +YT GL+ G +Y+ + +++ +R+
Sbjct: 14610 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 14668
Query: 1803 SPVVIDASTAIDAP 1816
+P A IDAP
Sbjct: 14669 TPPT-KAVDPIDAP 14681
Score = 94.4 bits (233), Expect = 1e-18
Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 18700 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 18757
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 18758 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 18805
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 18806 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 18865
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 18866 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 18925
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 18926 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 18985
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 18986 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 19037
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 19038 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 19097
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 19098 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 19155
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
L EY+ + A+ SP K T T P PP E VT++T+ + W P
Sbjct: 19156 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 19213
Query: 1110 APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
G K+ G + + AP ++ + +GL +Y +
Sbjct: 19214 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 19271
Query: 1152 -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
TI D + K + + TN+ L+A + TVSW++
Sbjct: 19272 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 19331
Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
T P G + + ++ CT + N +Y ++
Sbjct: 19332 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 19376
Query: 1254 KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
K S I ++ PP ++ + D ++W PP ++TN++V + +
Sbjct: 19377 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 19434
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
A++S + + + L+ G EY + + + P+ K D P D
Sbjct: 19435 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 19494
Query: 1366 -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
S+IT + TV W P + ITGY + + +R P ++ T L
Sbjct: 19495 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 19554
Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
GTEY + A+N + P G+ S S P +V T +S+ +SW
Sbjct: 19555 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 19609
Query: 1469 DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
PA + Y + ++ V+ +P + K+ ++GL Y VYAV
Sbjct: 19610 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 19668
Query: 1523 GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
G D P P I E + + ++ T + ++++ PV G
Sbjct: 19669 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 19725
Query: 1578 PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
+ P G D T + E + +Y++++ +N G+ + + V
Sbjct: 19726 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 19783
Query: 1630 TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
P P ++ +++ S W PP + + Y V+ E+ +
Sbjct: 19784 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 19842
Query: 1685 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
+S V+ L Y V+A + P + V + P +V ++++ +I
Sbjct: 19843 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 19902
Query: 1743 SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
W+ I G+ VD + + QR +K Y+ L G +Y + N+
Sbjct: 19903 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 19960
Query: 1799 NARSSP--VVIDASTAIDAP 1816
N +P + + A + AP
Sbjct: 19961 NGEGTPSEITVVARDDVVAP 19980
Score = 94.0 bits (232), Expect = 2e-18
Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)
Query: 710 TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
TV+ TP P+ E +I +S + W D + Y L ++ + +++
Sbjct: 14795 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 14851
Query: 767 DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
+ ST ++ L+ G++Y+ V + G +++ PDAP P V
Sbjct: 14852 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 14911
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
+ V S++V+W+ P+ +PI GY + E +ST + + L G+
Sbjct: 14912 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 14968
Query: 877 NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
+T ++ V + P + D + P P + + + + + W PP
Sbjct: 14969 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 15028
Query: 932 --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ GY VD ++ N +++ + + T E+ G Y +V AV+ E
Sbjct: 15029 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 15085
Query: 987 KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
P Q T +LD T+ + WT ++
Sbjct: 15086 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 15145
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
R+ + NVG + K LR + Y ++ G++ + V
Sbjct: 15146 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 15193
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
F P + P T ++ W+ + GF + + ++ + + ++
Sbjct: 15194 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 15251
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
++GL G EY + +V+ + P V V PL PPT+ + E
Sbjct: 15252 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 15309
Query: 1188 TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
T +T+ W+ + I GY I + + + + +S +NL Y
Sbjct: 15310 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 15366
Query: 1245 VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
V V + ES +P++ I PPT ++ DT++V P I D+T
Sbjct: 15367 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 15426
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
+ E V E P+D + + +E +S +V E + + +
Sbjct: 15427 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 15483
Query: 1357 GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
G P + +DI A S + W AP G I H+ + + R
Sbjct: 15484 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 15542
Query: 1402 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
+ + + ++ + L P +Y + A+N S + + D P
Sbjct: 15543 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 15602
Query: 1452 RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
+V+A T S+L+SW P + Y + E G +P+ + + G +
Sbjct: 15603 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 15662
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
+ L GV Y A+ G P S S P ++ + PS +V D +S
Sbjct: 15663 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 15720
Query: 1558 ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
IS+ W P + SP+ GY V + G T K PD+ T E + P ++ Y
Sbjct: 15721 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 15777
Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
V A N +GES+P T IPA TD++ + AQ V G ++R+
Sbjct: 15778 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 15832
Query: 1667 ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
TPK E G K ++ A +SS +++ + + S+
Sbjct: 15833 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 15892
Query: 1704 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
A K+ + A V ++ PP+ +V+D T + +SW+ + I G+ ++
Sbjct: 15893 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 15951
Query: 1760 PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
+G+ + + PD S T + L Y + N PV I +TA D
Sbjct: 15952 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 16009
Query: 1816 -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
P L+ T N++ +SW+PP+ + +T YI++ ++ G+ +
Sbjct: 16010 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 16069
Query: 1864 GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
V E T+ L G EY V A+ S+P
Sbjct: 16070 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 16102
Score = 93.6 bits (231), Expect = 2e-18
Identities = 266/1257 (21%), Positives = 449/1257 (35%), Gaps = 180/1257 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 27420 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 27479
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 27480 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 27538
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 27539 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 27593
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 27594 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 27651
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 27652 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 27711
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 27712 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 27771
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 27772 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 27831
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 27832 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 27889
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 27890 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 27945 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 27999
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 28000 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 28056
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 28057 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 28114
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 28115 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 28174
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 28175 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 28222
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P+ ++VTD ++S++W
Sbjct: 28223 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 28282
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 28283 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 28342
Query: 1627 T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
T AV + AP D F Q A +++L Y+ R TP + P
Sbjct: 28343 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 28397
Query: 1678 INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
++L D ++ S L V A KY ++V ++ S+ V L+ PP
Sbjct: 28398 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 28454
Query: 1730 ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
D T + T+ W I + V+ A+ ++ + K + + + L
Sbjct: 28455 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 28514
Query: 1786 GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
G Y + +N+ P I A+ P L + T+ +S +++W P
Sbjct: 28515 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 28574
Query: 1838 ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+RITGY+++ + GS V T+ L TEY V A + SEP
Sbjct: 28575 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 28629
Score = 92.8 bits (229), Expect = 3e-18
Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 26568 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 26627
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 26628 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 26685
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 26686 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 26744
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 26745 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 26803
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 26804 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 26860
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 26861 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 26920
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 26921 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 26980
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 26981 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 27037
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 27038 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 27097
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 27098 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 27157
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 27158 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 27213
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 27214 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 27273
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 27274 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 27329
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 27330 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 27384
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 27385 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 27442
Query: 1616 NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
N G +P T +PAP DL T TS+ WT P+ +T Y V
Sbjct: 27443 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 27502
Query: 1668 PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
K E+T I+ + + VS L + E V+A + S P G +T E +
Sbjct: 27503 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 27559
Query: 1726 PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
P + V + + ++ K + + D +P ++ +T
Sbjct: 27560 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 27619
Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
S + G Y + L DNA V + PS +RF +S++
Sbjct: 27620 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 27675
Query: 1831 VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
+SW P IT Y I+ + ++V T + L EY V A
Sbjct: 27676 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 27734
Query: 1887 KNNQKSEPLI 1896
S+PL+
Sbjct: 27735 NRYGVSQPLV 27744
Score = 91.3 bits (225), Expect = 1e-17
Identities = 267/1256 (21%), Positives = 445/1256 (35%), Gaps = 161/1256 (12%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
S+ + T +S ++SW EY + +G Q + + I ++ ++
Sbjct: 27470 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 27528
Query: 787 IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
V +++ E+ L ++ T + P VD D + VR Y+
Sbjct: 27529 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 27588
Query: 843 IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
PS+ L L E T N +TLS ++ + +N V
Sbjct: 27589 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 27648
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
I T G P P ++F E+ V + W PE +T Y ++ +
Sbjct: 27649 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 27704
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
++R TF +V L Y F+V A + S+PL A+ ++ P
Sbjct: 27705 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 27763
Query: 1005 FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
+ N T + + W P +++TG+ + ++ N P S +Y L
Sbjct: 27764 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 27823
Query: 1059 ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
+Y + A SP FT P P +VT TI + W P R G
Sbjct: 27824 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 27883
Query: 1116 K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
+ QG E R V + + V+GL+PG Y + I I
Sbjct: 27884 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 27929
Query: 1167 VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
V +SPP+ +E P+ G++ S E + R
Sbjct: 27930 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 27989
Query: 1212 PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
T + G +E+ ++ D T + + VYTV+ S V +
Sbjct: 27990 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
DT V P +RFTNI + M + W P + +T++++ ED
Sbjct: 28050 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 28106
Query: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
E + S A+ L N G EY VS+V + PL Q T D+P +
Sbjct: 28107 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 28160
Query: 1367 SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
S+IT NS T+ W P + I Y + + + + + P S +T LT G
Sbjct: 28161 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 28220
Query: 1422 TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
EY ++A N P LI + V+ P ++V + T++ + W P
Sbjct: 28221 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 28280
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
I Y + + ++ + K+ T++ L+ G +Y V A+ G+GDS
Sbjct: 28281 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 28340
Query: 1528 --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
+ K + E+D + + T V S++ ++ T V + P +
Sbjct: 28341 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 28400
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
+ +T+E ++ +N SG V P P + F V
Sbjct: 28401 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 28460
Query: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
T S + W P + G R+ EK + I+ V+ L Y
Sbjct: 28461 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 28519
Query: 1700 VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
V A+ + P + + E +PPRR V D ++++ ++W ITG
Sbjct: 28520 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 28579
Query: 1754 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
+ ++ ++ + ++T+ L T+Y+ + ND S P +S I
Sbjct: 28580 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 28638
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1866
P P + L IT +I K GSP VP RP P VT
Sbjct: 28639 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 28680
Score = 90.1 bits (222), Expect = 2e-17
Identities = 140/634 (22%), Positives = 237/634 (37%), Gaps = 93/634 (14%)
Query: 1358 LDSPTG---IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHS 1409
LDSP + S +T T+ W P+ A IT Y + R + E P
Sbjct: 29138 LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTL 29197
Query: 1410 RNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S +T L EY+ + A+N E P++ T+ P E V
Sbjct: 29198 --SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH 29255
Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT-----------------IS 1506
++I W P E+ G + + + V + + ++
Sbjct: 29256 IIIQWTKP------------ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVT 29303
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWL 1563
L G DY V AV G+S S I+ R PS +V D +SIS+ W
Sbjct: 29304 SLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 29363
Query: 1564 P----SSSPVTGYRVTTTPKNGPGPTKTKT-AGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
+ + GY + K+ + T A TE T+ L+ +Y V A N
Sbjct: 29364 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 29423
Query: 1619 G---------ESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1669
G E +P+ + + + DLK T S + V ++G V
Sbjct: 29424 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM---VSVSGRPPPVITW 29480
Query: 1670 EKTG---PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS--RPAQGVVTTLENV 1724
K G + I +S S+++ + +Y+ Y ++ S + A +V +
Sbjct: 29481 SKQGIDLASRAIIDTTESYSLLIVDKV--NRYDAGKYTIEAENQSGKKSATVLVKVYDTP 29538
Query: 1725 SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
P +V + + ++TI+W T + + V+ A + T K Y I
Sbjct: 29539 GPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRI 29598
Query: 1781 TGLQPGTDYKIY-----LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP 1835
+GL GT Y +Y + + +S V+ + + P+ L + T +++ ++W+
Sbjct: 29599 SGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEK 29657
Query: 1836 PR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1891
P +R+TGY+++ K G+ V +P V E T+T L G +Y + A
Sbjct: 29658 PLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGV 29717
Query: 1892 SEP-----LIGRKKTDELP--QLVTLPHPNLHGP 1918
SEP + + LP L T+P +H P
Sbjct: 29718 SEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 29751
Score = 89.7 bits (221), Expect = 3e-17
Identities = 131/594 (22%), Positives = 227/594 (38%), Gaps = 77/594 (12%)
Query: 1414 TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
T+T L G EY+ + A N ++P+ + V P ++ + +
Sbjct: 13149 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 13208
Query: 1466 ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
++W+ P + Y I + TV +AT++ + G +Y+ V A
Sbjct: 13209 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 13268
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S+ + I++PS + +D +S+ +KW P SP+ GY +
Sbjct: 13269 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 13328
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
+ + + + GL+ +Y+ V A+N +G S P + I
Sbjct: 13329 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 13382
Query: 1635 PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
P V PT LSA + PN V TGY R T +TG +
Sbjct: 13383 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 13442
Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
+ + +V+S + + + +Y LK + G V + S P+ + D
Sbjct: 13443 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 13499
Query: 1736 TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
T+ ++ ++W + +TG+ V+ + +T + +T+ L G +Y
Sbjct: 13500 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 13559
Query: 1792 YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
+ N P +D +T D P N+++ T NS+ ++W PP+ +RI
Sbjct: 13560 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 13619
Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
GYI++ GS P T+ +TGLE G Y V AL S+P +
Sbjct: 13620 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRP 13675
Query: 1901 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQP 1954
T+E+ + T P + LDV T G I+LP T +P
Sbjct: 13676 TEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTGKP 13718
Score = 89.4 bits (220), Expect = 4e-17
Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)
Query: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
S P E+ E P+ P S P+ + K+I + W+P KN +G E G
Sbjct: 14270 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 14327
Query: 662 -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
+NS IK LK GVV + + + ++ G E + + P
Sbjct: 14328 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 14386
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
T+ ET + S+ + + V VS + L+ + D
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 14439
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ + +P + I + ++ G + ++ P D + +S
Sbjct: 14440 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 14497
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
+ W P+ PI Y + + + + E S T+ DL P +Y + AV
Sbjct: 14498 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 14557
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
+ + ++ P D++ T +TI W PP S + GY ++
Sbjct: 14558 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 14617
Query: 941 VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
I GE + +PI T GL G Y F+V A + S+P A
Sbjct: 14618 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 14671
Query: 995 TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
TK +DAP T+L+ V D L + W I +
Sbjct: 14672 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 14730
Query: 1032 GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
L RR Q + V P + + N + Y + + G
Sbjct: 14731 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 14790
Query: 1074 ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
++P V T PG I ++ +T+++ W P G + + E +
Sbjct: 14791 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 14846
Query: 1134 DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
DS IVV+ L G EY++ ++ + P V+K + P PP
Sbjct: 14847 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 14905
Query: 1179 -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
+ + + + + V W + I GY + N + + + + + D
Sbjct: 14906 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 14964
Query: 1236 NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
L GL Y V + P SD P PP P R T+ T+ + W P
Sbjct: 14965 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 15024
Query: 1290 PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
P ++ + V V E + + G +Y + VS+V E
Sbjct: 15025 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 15084
Query: 1347 STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
P + T + P ++ + + G +R P +GRP
Sbjct: 15085 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 15135
Query: 1405 RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
+V ++ + + N+ +E ++ I A N + V
Sbjct: 15136 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 15193
Query: 1448 SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
DVP DL+ V L++W P E G S + F +
Sbjct: 15194 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 15241
Query: 1500 ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
+S I+GL G +Y V A G P P+ I +D
Sbjct: 15242 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 15297
Query: 1545 PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
P ++ T+ ++I++ W SP+ GY + + P + T +E
Sbjct: 15298 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 15357
Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
L Y V A N GES+P ++P ++ +V PT LS + V
Sbjct: 15358 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 15410
Query: 1658 QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
+ G V + P + TG PM +I + + + + + + TK EVS V
Sbjct: 15411 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468
Query: 1703 YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
K T T + + + NV SPPR VTD + ++W +
Sbjct: 15469 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 15528
Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
IT + +D A+ + + + Y I L P Y+ + Y ++D +S
Sbjct: 15529 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 15588
Query: 1804 PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
VVI D P + LA T S+LVSW PP + ITGY ++ + GSP V
Sbjct: 15589 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 15648
Query: 1859 PRPRPGVTEATITGLE 1874
R +T+ + G+E
Sbjct: 15649 --SRAPITKVGLKGVE 15662
Score = 89.4 bits (220), Expect = 4e-17
Identities = 289/1431 (20%), Positives = 507/1431 (35%), Gaps = 177/1431 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ P++ P ++ + + NS + W P+ S I +YI+ +
Sbjct: 23113 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 23170
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K+S +W E L + I L G Y +++++ + G + S + P+
Sbjct: 23171 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 23221
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E + S V + +S T++ + L +
Sbjct: 23222 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 23280
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
L T S+ G +Y + V + G+++ + PD P P D V
Sbjct: 23281 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 23338
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
SI + W+ P IT Y + + ++ ++ ++ L+ G +Y I+
Sbjct: 23339 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 23398
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
A EN+ ++ + P P F ++ + I W P S V G
Sbjct: 23399 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 23456
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
Y ++ N I +T + L G+ Y F+V+A V G+ SK
Sbjct: 23457 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 23516
Query: 994 TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
D P + + + + ++WT P + ITGY + G+ + + +
Sbjct: 23517 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 23576
Query: 1049 -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
+++ + L Y ++A G P +TG T P S+ P + +
Sbjct: 23577 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 23633
Query: 1101 TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
T +V + P P I + G + + + T ++V
Sbjct: 23634 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 23693
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
Y ++ + P+ KV+ PP + +++W + DI+
Sbjct: 23694 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 23753
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
Y + T+ + V + T L G EY V+ Y V + ES P+
Sbjct: 23754 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 23811
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
+ ++P PP L TNI D+M V W P S + + ++ + + +
Sbjct: 23812 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 23869
Query: 1318 P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
+D + +T L EY VS + E +P K PT
Sbjct: 23870 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 23929
Query: 1368 DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
D T NS T+ W P + I GY + E E ++ + + +T L
Sbjct: 23930 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 23985
Query: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
T EY + + ALN + +G+ ++V + + + A P L S + VR
Sbjct: 23986 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 24039
Query: 1477 -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
RI G +P ++ + T + ++ GV+YT Y +
Sbjct: 24040 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 24098
Query: 1525 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
S + S +++ P + V +V+ +S + W P + V Y +
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 24158
Query: 1581 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
++ +T +E L Y V A+N G P+ V+ A P P
Sbjct: 24159 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 24216
Query: 1636 TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
+ T V+ TS S W P ++ GY V + PK EK + E + + VV
Sbjct: 24217 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 24272
Query: 1690 SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
+GL +Y+ V A + S P GV +T ++ P A E
Sbjct: 24273 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 24332
Query: 1738 ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
ISW E + T V+ + I+ K D YT+T
Sbjct: 24333 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 24391
Query: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
T +N S +V++ P +RF + + +++SW+PP +I+ YI
Sbjct: 24392 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 24441
Query: 1845 IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
++ + +V T IT L+ GTEY + A KS PL
Sbjct: 24442 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPL 24491
Score = 89.4 bits (220), Expect = 4e-17
Identities = 339/1648 (20%), Positives = 590/1648 (35%), Gaps = 249/1648 (15%)
Query: 611 PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
P + TE P+ P +S + W P S I+ Y+L R K S W EA
Sbjct: 28537 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 28595
Query: 658 TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
GH ++T++ L YE ++ + G+ E R F++ P T +TG
Sbjct: 28596 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 28651
Query: 714 ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
T A S ++ S V+ +++E +E D + T
Sbjct: 28652 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 28703
Query: 774 SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
++ + D + G +Y + + + G ++ ++ P P V V S V+
Sbjct: 28704 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 28761
Query: 831 WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
W P+ IT Y + S + +N + ++ L ++Y+ + +
Sbjct: 28762 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 28821
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
V + ES P++ + P + T P + V+ ++I W P S + GY
Sbjct: 28822 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 28875
Query: 938 RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
V+ N + ++P + +VTGL G+ Y F+ +A VS E S+P+
Sbjct: 28876 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 28934
Query: 991 AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
AQ +DAP + + T STV + W+ P +++ GY +
Sbjct: 28935 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 28992
Query: 1030 ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
TV G ++ V ++K + SE T V + PKA
Sbjct: 28993 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 29048
Query: 1080 -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
G T++ GS + + P P+I + G + E + T
Sbjct: 29049 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 29100
Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
+ V+ YT+ V + ++ KV+ P L + + T+
Sbjct: 29101 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 29159
Query: 1194 SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
+W S + G IT ++ + L V+ S L EY V V
Sbjct: 29160 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 29217
Query: 1251 KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
VP+ I A +P PP G + + + W P S +++N+LV
Sbjct: 29218 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 29277
Query: 1301 -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
R++ V + V D + +T+L+ G +Y V++V S P
Sbjct: 29278 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 29330
Query: 1354 QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
P+ D T +S ++ W P I GY + + R
Sbjct: 29331 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 29390
Query: 1403 EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
RN+ T+ +L G +Y + A+N G E I + V ++P DLE+
Sbjct: 29391 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 29449
Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
++ I A R+ +G PV ++ G A+ + + Y++
Sbjct: 29450 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 29502
Query: 1518 V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
+ Y + S S + + Y T PS ++V +V +S+++ W
Sbjct: 29503 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 29561
Query: 1563 -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
+ +PV Y + + KT T +T I GL Y V +N G
Sbjct: 29562 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 29620
Query: 1622 QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
+P + V+ +P P L+ VT ++++ W P +LTGY +
Sbjct: 29621 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 29680
Query: 1674 PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
MK + L P V+ L +Y E V ++T+T+ Q V+ T++
Sbjct: 29681 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 29740
Query: 1724 VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
+ P++ A E I I+ R F + + + ++ K +
Sbjct: 29741 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 29800
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
T ++ +Y + L + + VI ++ S+ +SW+PP
Sbjct: 29801 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 29860
Query: 1838 -ARITGYIIKY---EKPG-SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
A ++GY+++ +PG P E V R + T L G EY V A N+
Sbjct: 29861 GAPLSGYVVEQRDAHRPGWLPVSESVTR-----STFKFTRLTEGNEYVFRVAA--TNRFG 29913
Query: 1893 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSG 1951
+ + E + +P P PE L + + +T +P D G G Q+ G
Sbjct: 29914 IGSYLQSEVIECRSSIRIPGP----PETLQIFDVSRDGMTLTWYPPEDDG-GSQVTGY-- 29966
Query: 1952 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPH 2011
V ++ + + R P T T R+R + E ++ I P
Sbjct: 29967 ---IVERKEVRADRWVRVNKVPVTMT--RYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 30021
Query: 2012 GP--GLNPNASTGQEALSQTT--------ISWAPFQD-----TSEYIISCHPVGTDEEPL 2056
P ++P A G+ + T ++W+ +D + Y+I V E
Sbjct: 30022 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 30081
Query: 2057 QFRVPGTSTSATLTGLTRGATYNIIVEA 2084
P TLT L +GA Y V A
Sbjct: 30082 CNTTPTKIREYTLTHLPQGAEYRFRVLA 30109
Score = 88.2 bits (217), Expect = 8e-17
Identities = 177/778 (22%), Positives = 292/778 (37%), Gaps = 127/778 (16%)
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
T ++L G EY V V S P + D P +PP DL+ TN+
Sbjct: 16077 TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 16136
Query: 1279 -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
G +TW APP D PV + V +L + + V+ +
Sbjct: 16137 VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 16190
Query: 1332 TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
T + +V+++ + L + G P G I F ++A+ T+ W P+ +
Sbjct: 16191 TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 16248
Query: 1385 ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
IT Y I H S P+E + T+ L G EYV I+A N
Sbjct: 16249 ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 16301
Query: 1435 --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
+ P +V P V + T S+ ++W+ P V Y + +T
Sbjct: 16302 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 16361
Query: 1489 -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
P++ T+ S ++GL G DY VYA+ G PAS S P +
Sbjct: 16362 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 16418
Query: 1540 TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
P +VTD +S ++W P S VTGY V + K K T
Sbjct: 16419 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 16478
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
++ + GL+ Y V A N +G +P T V ++K V+P L A
Sbjct: 16479 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 16532
Query: 1655 PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 16592
Query: 1703 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 16652
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 16653 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 16710
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 16711 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 16770
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 1916
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 16771 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 16821
Score = 84.7 bits (208), Expect = 9e-16
Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 13186 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 13245
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 13246 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 13300
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 13301 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 13360
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 13361 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 13420
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 13421 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 13476
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 13477 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 13531
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 13532 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 13591
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 13592 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 13649
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
L G Y V + S P T I AV
Sbjct: 13650 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 13708
Query: 1272 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
+L T G ++TW I + + V + V + SD G
Sbjct: 13709 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 13759
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
T + +V+ + K G P D +D+T S + W PR + IT
Sbjct: 13760 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 13817
Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
Y + R + V H +S T L P EY+ + A N +
Sbjct: 13818 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 13870
Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
SP+ Q P LE T ++ ++W P + Y + + + V
Sbjct: 13871 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 13930
Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
+ +P +T + GL Y V A + G G S++PI I + ID P
Sbjct: 13931 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 13988
Query: 1547 QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
+ V DV S+ + W + + Y V K G G T+ + GL
Sbjct: 13989 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 14047
Query: 1603 QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
EY V A N +GES+P L + + P L+ +T + +WT P
Sbjct: 14048 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 14107
Query: 1656 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
+T Y V + G + ++ + V+ L E S+Y + +
Sbjct: 14108 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 14161
Query: 1712 RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
Q T +E+ PP V D T+ + + W I + ++
Sbjct: 14162 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 14221
Query: 1758 AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
G ++ +T PD ++ +T + GT+ + + N+ P + D
Sbjct: 14222 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 14280
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
++ P +L + ++W+PP + I GY ++ G+ V RP
Sbjct: 14281 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 14340
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ G+ P EY + V A+ SEP
Sbjct: 14341 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 14371
Score = 83.6 bits (205), Expect = 2e-15
Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 22350 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 22409
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 22410 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 22454
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 22455 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 22514
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 22515 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 22572
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 22573 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 22626
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 22627 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 22683
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 22684 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 22743
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 22744 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 22802
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 22803 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 22862
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 22863 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 22922
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 22923 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 22979
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 22980 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 23034
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 23035 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 23093
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 23094 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 23153
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 23154 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 23211
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 23212 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 23269
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 23270 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 23321
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 23322 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 23381
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
+ + L+ EY ++A+N G ES P+V P P F T ++
Sbjct: 23382 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 23435
Query: 1645 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
S+ QW P + GY + + K + L +YE
Sbjct: 23436 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 23495
Query: 1701 SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
VYA + ++ + PP IT+ W ITG+
Sbjct: 23496 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 23555
Query: 1755 QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
V+ P R +K + +T++GL Y+ + N
Sbjct: 23556 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 23599
Score = 82.0 bits (201), Expect = 6e-15
Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 27775 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 27834
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 27835 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 27879
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 27880 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 27939
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 27940 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 27994
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 27995 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 28053
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 28054 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 28109
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 28110 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 28168
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 28169 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 28227
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 28228 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 28286
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 28287 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 28345
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 28346 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 28405
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 28406 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 28464
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 28465 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 28523
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 28524 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 28583
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 28584 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 28640
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 28641 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 28696
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 28697 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 28748
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 28749 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
+EY V ++N G S+PL + +P APT + V+ ++S +W P
Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 28867
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++ GY V + +KE + + V+GL+ +Y+ YAL S+ +
Sbjct: 28868 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 28927
Query: 1715 QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
+ + V P R VTD T +T+++ W + G+ ++ P +
Sbjct: 28928 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 28987
Query: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
TI D +T+T L G Y+ + N
Sbjct: 28988 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 29020
Score = 79.3 bits (194), Expect = 4e-14
Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)
Query: 1412 SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
S +T L G EY I+A+N E P++ V D P+ EV T S++
Sbjct: 22695 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 22754
Query: 1466 ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
+ W+ PA + Y + + G + + ++GL DY V A
Sbjct: 22755 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 22814
Query: 1522 TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
G SP S+ + + + P+ +V D+ +S+ + W + GY V
Sbjct: 22815 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 22874
Query: 1575 TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
+ G T G ++T + +E L EY + A N +G + +V+
Sbjct: 22875 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 22934
Query: 1627 TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
+ DL+ ++ + R TP+ K G +++ +
Sbjct: 22935 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 22990
Query: 1683 DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
+SS L +Y+ Y L +++ ++ A V L+ SPP +VT+ T+ ++
Sbjct: 22991 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 23050
Query: 1741 TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
+I+W I + V+ A ++ S+ I LQ G Y +
Sbjct: 23051 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 23110
Query: 1797 NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
N+ P I + P + T NS+ +SW P ++I YI++ +
Sbjct: 23111 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 23170
Query: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
S R + +A IT L G EY V+A+ +S+P
Sbjct: 23171 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 23214
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 26068 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 26127
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 26128 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 26179
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 26180 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 26231
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 26232 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 26289
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 26290 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 26349
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 26350 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 26406
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 26407 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 26460
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 26461 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 26511
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 26512 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 26571
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 26631
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 26632 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 26690
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 26746
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 26747 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 26791
Score = 75.5 bits (184), Expect = 6e-13
Identities = 200/944 (21%), Positives = 346/944 (36%), Gaps = 118/944 (12%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 21557 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 21613
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 21614 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 21673
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 21674 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 21733
Query: 1071 -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
+P T F T +PG PP N V +T +I I W + G+
Sbjct: 21734 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 21790
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 21791 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 21849
Query: 1169 KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 21850 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 21908
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 21909 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 21968
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E + + ++ + + + L G Y V +
Sbjct: 21969 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 22027
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 22028 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 22087
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V T+T L G EY + A N E + +Q +V + +
Sbjct: 22088 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 22142
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 22143 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 22200
Query: 1504 --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
++ +K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 22201 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 22257
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 22258 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 22314
Query: 1612 VYAQNPSGE-----SQPLVQTAVTTIPAPTDLK-FTQVTPTSLSAQWTPP----NVQLTG 1661
+ A+N G+ S+P V +P P T + S+ QW P ++ G
Sbjct: 22315 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 22374
Query: 1662 YRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GV 1717
Y + KE+ + ++N P + +GL +YE V A +P++
Sbjct: 22375 YHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSEC 22432
Query: 1718 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
+ PP R T ++T+ W+ T ITG+ V+
Sbjct: 22433 YVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 22476
Score = 75.1 bits (183), Expect = 7e-13
Identities = 125/581 (21%), Positives = 213/581 (36%), Gaps = 71/581 (12%)
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWD 1469
+ + N T S+ +N E + + + V D P DL+V T TS +SW
Sbjct: 18663 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVR--VLDTPGPVSDLKVSDVTKTSCHVSWA 18720
Query: 1470 AP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
P V +Y + E + T K++ ++ L PG +Y V AV G
Sbjct: 18721 PPENDGGSQVTHYIVEKREADRKT-WSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 18779
Query: 1526 DSPASSKP---ISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
+ P ++ + +E D P +++VT++ NS ++ WLP + + GY +
Sbjct: 18780 PGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 18839
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTTIPA 1634
+ P T+ + + + GL+ +Y V A+N G S P V A +
Sbjct: 18840 EEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLP 18899
Query: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
P L Q+T + G ++R+ P VV S +
Sbjct: 18900 PKILMPEQITIKA-------------GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 18946
Query: 1695 ATKYE-VSVYALKD---------TLTSRPAQGV------VTTLENVSPPRRA-RVTDATE 1737
K + S+ +KD +LT+ + G V ++ PP+ ++D
Sbjct: 18947 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 19006
Query: 1738 TTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
++SW E IT + V+ + + S + L PG +Y +
Sbjct: 19007 DACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRV 19066
Query: 1794 YTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGY 1843
N S P+ A P N R + + V+W P + I GY
Sbjct: 19067 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 19126
Query: 1844 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 1903
+I+ ++ S TE GL G EY+ + AL S P K T+
Sbjct: 19127 LIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPP---SKPTEY 19183
Query: 1904 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGI 1944
+ + + P PE++DV + + P +D G+ I
Sbjct: 19184 VTARMPVDPPG--KPEVIDVTKSTVSLIW-ARPKHDGGSKI 19221
Score = 72.0 bits (175), Expect = 6e-12
Identities = 284/1399 (20%), Positives = 497/1399 (35%), Gaps = 195/1399 (13%)
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
G + I+ H++ + T + P S TV+ + P V+EI S
Sbjct: 17271 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 17327
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
++W D Y + E D P +ATS L G +Y+ V
Sbjct: 17328 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 17386
Query: 794 SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
++ G + + A D PP P D VD T + + W++P +PITGY +
Sbjct: 17387 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 17446
Query: 844 VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
Y EG+ + N ++ LQ G Y + A V T + I+ +
Sbjct: 17447 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 17504
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
P S + D++ +E VK P + + G V G + +
Sbjct: 17505 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 17559
Query: 957 SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
+ F+ V + + T +++ VS+ SK + A T LD P + ++ T
Sbjct: 17560 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 17617
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ + W PP+ + + Y + TR+ + G S +K + +LQ EY
Sbjct: 17618 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 17677
Query: 1066 LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
+ A P T + S P P T++TE ++WT +P G
Sbjct: 17678 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 17737
Query: 1115 FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
+ + R G T + V+GL G Y + + G + +P + +
Sbjct: 17738 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 17797
Query: 1171 ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
+ P PP N L+ + + W + + I GY + Q N + +
Sbjct: 17798 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 17856
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
Q + L G EY + E P +++++I PP +L T
Sbjct: 17857 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 17916
Query: 1280 PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 17917 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 17974
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 17975 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 18025
Query: 1382 R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
+ IT + + + + G R + NL EY + A N
Sbjct: 18026 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 18083
Query: 1434 ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
++P+L P +L + T + + W P ++Y G
Sbjct: 18084 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 18143
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
+ + K T + + V+ I + V + + S K + + ++ KP
Sbjct: 18144 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 18201
Query: 1546 SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
V D +S V + + + R+ + P P T D T++T
Sbjct: 18202 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 18251
Query: 1599 IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
I+ + ++ ++ V A N +G V P P +LK V+
Sbjct: 18252 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 18311
Query: 1647 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
+ W PP G ++ EK K + + S++V+ G V E + Y +
Sbjct: 18312 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 18369
Query: 1707 DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
++ G T + V P VT ++ +T+ W ++ITG
Sbjct: 18370 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 18429
Query: 1754 FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
+ ++ + P+ ++ P+ R + L P +Y+ + N+ + S PV
Sbjct: 18430 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 18488
Query: 1806 VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
V D P+N R + TT +S+ + W P A I GY+++ + P E
Sbjct: 18489 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 18548
Query: 1859 PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 1914
R E T+T L+ EY V A NQ +G + EL + + P
Sbjct: 18549 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEI 18600
Query: 1915 LHGPEILDVPSTVQKTPFV 1933
L PEI D+ ++++K V
Sbjct: 18601 LEPPEI-DLDASMRKLVIV 18618
Score = 68.2 bits (165), Expect = 9e-11
Identities = 218/1049 (20%), Positives = 384/1049 (36%), Gaps = 174/1049 (16%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 13092 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 13151
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 13152 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 13209
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 13210 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 13268
Query: 1251 KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
P + T V PP +L ++ ++++ W PP S L +
Sbjct: 13269 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 13328
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
R K+ + + P + +T L G +Y+ VS+ + S P D
Sbjct: 13329 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 13387
Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
D++A + I P +P + D+V + + + + L+
Sbjct: 13388 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 13447
Query: 1420 PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
E V+S + + L L + T+S P++L+ T S+ ++
Sbjct: 13448 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 13507
Query: 1468 WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
W+ P + G SP+ + V + + T+ L G
Sbjct: 13508 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 13555
Query: 1513 DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
+Y V A G G+ +P++++ + D P ++ D NSI + W P
Sbjct: 13556 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 13615
Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + GY V P+ G K G +T+M + GL+ Y V A N G S+P
Sbjct: 13616 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 13672
Query: 1624 LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
T AV T AP L T L A T P ++T + + K
Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 13732
Query: 1670 EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
+ K I + P S+V + + + + + Y ++ A VV L+
Sbjct: 13733 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 13785
Query: 1726 PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
PP +TD T + ++W + IT + V+ + + + T+K ++
Sbjct: 13786 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 13843
Query: 1780 ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
T L P +Y +Y + + ++SP I A D P+ L T +++ +
Sbjct: 13844 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 13901
Query: 1832 SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
+W P + ITGY ++ P + + T + GL +Y V+A
Sbjct: 13902 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 13961
Query: 1887 -----KNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTG 1941
K ++ +EP++ + D P P P + DV T + + T P +D G
Sbjct: 13962 LAGPGKPSKSTEPILIKDPIDP-------PWPP-GKPTVKDVGKTSVRLNW-TKPEHDGG 14012
Query: 1942 NGIQ--------------------LPGTSGQQPSV--GQQMIFEEHGFRR---TTPPTTA 1976
I+ +P T P + GQ+ F + + P +
Sbjct: 14013 AKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPS 14072
Query: 1977 TPIRHRPRPYPPNVGEEIQIGHIPREDVD 2005
P+ R + YPP+ +++ +I + D
Sbjct: 14073 DPVLCREKLYPPSPPRWLEVINITKNTAD 14101
Score = 62.8 bits (151), Expect = 4e-09
Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 26527 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 26581
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 26582 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 26641
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 26642 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 26699
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 26700 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 26756
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 26757 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 26814
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 26815 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 26874
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 26875 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 26930
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 26931 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 26990
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 26991 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 27050
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 27051 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 27106
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 27107 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 27164
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 27165 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 27282
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 27283 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 27342
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 27343 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 27459
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 27460 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 27516
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
T E+ + L+ V+A+N G S P+ TI P +K +TP LS
Sbjct: 27517 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 27566
Query: 1653 TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
P Q+T G+ V + K P I+ D + S + +K E + ++K+
Sbjct: 27567 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 27626
Query: 1709 LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
+ V T+ + PP + R + ++ +SW +
Sbjct: 27627 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 27686
Query: 1751 --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
IT + ++ QT + R ++ + L +Y+ + N S P+V
Sbjct: 27687 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 27745
Query: 1808 DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
A P T + + ++W P + +TG+ ++ ++ S +
Sbjct: 27746 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 27805
Query: 1858 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V E TGL G +Y V A + S P
Sbjct: 27806 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 27842
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 15492 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 15549
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 15550 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 15602
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 15603 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 15656
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 15657 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 15716
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 15717 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 15776
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 15777 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 15808
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 30726 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 30780
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 30781 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 30840
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 30841 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 30900
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 30901 CENLGGESEWSEISEPI--TPKSD 30922
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 31109 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 31166
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 31167 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 31226
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 31227 EVDETREVSMT 31237
Score = 35.8 bits (81), Expect = 0.50
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)
Query: 1534 ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
+ + + + DKP+ V + + NS + W P + S +T Y V +
Sbjct: 30715 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 30774
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
++ T I L Y V AQN G S PL ++V I +P + T
Sbjct: 30775 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 30834
Query: 1642 QVTPTSLSAQWTPP 1655
VT S W PP
Sbjct: 30835 AVTKDSCVVAWKPP 30848
Score = 31.6 bits (70), Expect = 9.4
Identities = 38/169 (22%), Positives = 66/169 (39%), Gaps = 21/169 (12%)
Query: 2027 SQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081
S ++SW+ +D + Y I TD+ + T+T T+TGL A Y
Sbjct: 30344 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 30403
Query: 2082 VEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESG 2138
+ A D + E VV + ++P+ + ++S +V +WE+ G
Sbjct: 30404 IIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDG 30458
Query: 2139 FKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2187
K + LG+ + + S W N K D+Q G ++ T
Sbjct: 30459 GK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 30499
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 148 bits (373), Expect = 7e-35
Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 22915 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22973
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 22974 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 23023
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 23024 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23080
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 23081 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23140
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 23141 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23200
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 23201 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23252
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 23253 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23311
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 23312 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23369
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 23370 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23428
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 23429 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23488
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 23489 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23548
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 23549 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23606
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 23607 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23666
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 23667 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23726
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 23727 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23786
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 23787 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23838
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 23839 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23897
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 23898 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23956
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 23957 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 24013
Query: 1629 VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
T P + + VT +S+S W+ P ++TGY + ++
Sbjct: 24014 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24073
Query: 1677 EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
++ V+GL+ +Y+ + A D + TS ++ VV + S P
Sbjct: 24074 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24133
Query: 1732 VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
+ ++ ++T+ W + I G+ V+ +G + +++ K + + +TI GL
Sbjct: 24134 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 24192
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
T+Y+ ++ N+ S P
Sbjct: 24193 ATEYEFRVFAENETGLSRP 24211
Score = 140 bits (353), Expect = 1e-32
Identities = 320/1467 (21%), Positives = 549/1467 (37%), Gaps = 222/1467 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13485 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13541
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13542 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13586
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13587 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13643
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13644 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13703
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13704 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13761 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13813
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13814 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13872
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13988
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13989 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 14048
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 14049 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14107
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 14108 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14160
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 14161 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14210
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 14211 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14270
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 14271 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14330
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 14331 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14390
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 14391 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14450
Query: 1526 -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 14451 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14510
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
+ + + I T ++V+++ +NP+G+ V V P P +
Sbjct: 14511 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14568
Query: 1638 LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
L+ T +T S++ W P + ++T Y V +++ K + A + V+
Sbjct: 14569 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 14624
Query: 1691 GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
GL +Y V A + P + V E SPP + D T++T++++W
Sbjct: 14625 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 14684
Query: 1745 RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
ITG+ ++A + Q T+K + L G +Y + +N RS+
Sbjct: 14685 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 14742
Query: 1804 -----PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 1858
PV++ T + +LR + +Q G IK E P V+
Sbjct: 14743 PRESRPVIVKEQTML-PELDLRGI----------YQKLVIAKAGDNIKVEIP------VL 14785
Query: 1859 PRPRPGVT---------EATITGLEPGTEYTIYVI--ALKNNQKSEPLIGRKKTDELPQL 1907
RP+P VT + E TI I ++++ PL R E+ +
Sbjct: 14786 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 14845
Query: 1908 VTLPHPNLHGPEILDVPSTVQKTPFVT 1934
+T+ ++ GP + + FVT
Sbjct: 14846 ITIQVHDIPGPPTGPIKFDEVSSDFVT 14872
Score = 129 bits (323), Expect = 4e-29
Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7471 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7529
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7576
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7577 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7636
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7637 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7696
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7754
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7755 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7814
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7815 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7873
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7874 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7933
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7934 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7993
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7994 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 8052
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 8053 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8106
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 8107 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8165
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 8166 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8225
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8285
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 8286 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8343
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 8344 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8403
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 8404 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8463
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 8464 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8523
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 8524 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8583
Query: 1624 LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
V + AP VT S+ +W P + GY + T
Sbjct: 8584 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8643
Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
+ ++ V GL+ Y V A + P T + +SPP
Sbjct: 8644 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 8703
Query: 1731 RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
RVTD + TTI + W I G+ VD + T K VR YT+ ++
Sbjct: 8704 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 8763
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
G DYK+ + +N P
Sbjct: 8764 GADYKLRVSAVNAAGEGPP 8782
Score = 128 bits (321), Expect = 7e-29
Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 7131 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7186
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 7187 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7246
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 7247 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7306
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 7307 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7365
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7420
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 7421 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7473
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 7474 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7530
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 7531 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7589
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 7590 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7648
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
V K K + P I D I P PP PT ++G ++R+ W P
Sbjct: 7649 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 7705
Query: 1292 -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
+ ++++ +E V P+ +L L+ G EY V +V + E
Sbjct: 7706 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 7764
Query: 1347 --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
S P+ R+K S P ++ +IT N+ + W P + IT Y + G
Sbjct: 7765 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7824
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
D T+T LT G+ YV + A N E +L T P
Sbjct: 7825 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7883
Query: 1453 DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
L VV T + + W+ P ++ Y I E G V+ G ++ +
Sbjct: 7884 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7943
Query: 1509 KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
G + V A G G ++ +SI T P + VTD I++ W P
Sbjct: 7944 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 8003
Query: 1565 ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
SP+ GY V P + + + + EG+ P EYV+ V A N G
Sbjct: 8004 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 8063
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
S+P + + + D K T T + + G ++ + + P+ ++
Sbjct: 8064 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 8115
Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
D V S + +S + L+ + R G+ T TLEN
Sbjct: 8116 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174
Query: 1724 VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
P + + +D T+++ ++W I + ++ A +T I + S+T
Sbjct: 8175 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8234
Query: 1780 ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
+ L P +Y + +N ++ + D D P ++ T ++ ++
Sbjct: 8235 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8294
Query: 1833 WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
W+PP ++I GYII+ G + + T GLE G EY V A
Sbjct: 8295 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8354
Query: 1889 NQKSEP 1894
SEP
Sbjct: 8355 AGISEP 8360
Score = 127 bits (318), Expect = 2e-28
Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 12000 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 12058
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 12059 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12118
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 12119 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12176
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 12177 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12236
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 12237 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12295
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 12296 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12354
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 12355 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12412
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 12413 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12469
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 12470 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12528
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 12529 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12587
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 12588 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12641
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 12642 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12701
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 12702 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12760
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 12761 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12810
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 12811 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12868
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 12869 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12928
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
+ TA Q E T GL+ +Y + + + +TAV P P+D
Sbjct: 12929 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 12977
Query: 1638 LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
P ++ A+ PP + L+ + +T K T PM ++ D +
Sbjct: 12978 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 13030
Query: 1687 V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
+ G+ +A + + L KD T+T+ + G + L+ PP
Sbjct: 13031 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13090
Query: 1731 RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
++ +SW E IT + VD + Q + + S ++ L G
Sbjct: 13091 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 13150
Query: 1787 TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
+Y+ + N PV + A D P T + + VSW+PP
Sbjct: 13151 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 13210
Query: 1838 -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
+ ITGY++ EK + R + E T+ TGL+ GTEY V A+ +P
Sbjct: 13211 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 13268
Score = 125 bits (314), Expect = 5e-28
Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
N+ + W P S I+ Y + R K S+ RW A P + GL+ G YE
Sbjct: 14281 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14339
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ + + G + S++V + + P ++ VT+ T S ++
Sbjct: 14340 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14387
Query: 740 W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W ++G+ VE++ + GDE D TA + +PDL KY +
Sbjct: 14388 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14445
Query: 793 ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
I++ G + ++ + + PD +D ++VVR R PI G +P
Sbjct: 14446 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14502
Query: 849 VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
V + +NL AN ++ + + I ++ V+ E +S V
Sbjct: 14503 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14556
Query: 908 ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
P P +L+ ++T VT+ W P S +T Y V+
Sbjct: 14557 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14616
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
+ T+ +VTGLS G Y+F+V A + +P + K P +L ++ T ST
Sbjct: 14617 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14675
Query: 1013 VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
V + W P+ ++ITGY + R+G + ++ + +RNL EYT ++
Sbjct: 14676 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14733
Query: 1068 AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
A+ S ++ + +P + +VI P P +
Sbjct: 14734 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14793
Query: 1115 FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+K G + Q E T+ S + ++ Y + E I +V
Sbjct: 14794 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14853
Query: 1174 LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PPT + +T SW E I+ Y + T+ L V
Sbjct: 14854 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14913
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
T L+ GLEY V I+ I A VP PP + T + D+M
Sbjct: 14914 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14971
Query: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
++W P S + L + K + ++S + N + L G Y V +
Sbjct: 14972 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 15031
Query: 1342 YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
+S P + + +D P +IT ++ T+ W P T IT Y +
Sbjct: 15032 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15091
Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
+ + N T++ LT Y ++A N I S SD
Sbjct: 15092 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 15147
Query: 1454 LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
+ V A + + + + +R+ +G P E++ G + T
Sbjct: 15148 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15207
Query: 1512 VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
D++ + A T +P N + +D+P + VT+V
Sbjct: 15208 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 15266
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
+ W P + + Y V + T + T++ + L EY+ V
Sbjct: 15267 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 15325
Query: 1614 AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
A N G +PL V + P + + T +T S+ W P+ ++ Y
Sbjct: 15326 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 15385
Query: 1664 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
V K +K VSGL +YE + A S P+
Sbjct: 15386 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15445
Query: 1719 TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 15446 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 15502
Query: 1774 DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
SYTITGL +YKI +Y +N P ++
Sbjct: 15503 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15540
Score = 123 bits (308), Expect = 2e-27
Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13179
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 13180 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13239
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13240 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13299
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13300 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13359
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13360 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13418
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13479 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13536
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13537 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13593
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13594 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13648
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 13649 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13705
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 13706 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13756
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 13757 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13813
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 13814 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13873
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 13874 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13933
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 13934 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13993
Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 13994 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 14053
Query: 1623 PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
++ T I APT + L+ + + L + P K+ K
Sbjct: 14054 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 14111
Query: 1677 ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
+I P SS + + AT+ + Y + T ++ VT L+
Sbjct: 14112 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 14168
Query: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
PP +++ + T++W E + +T + + D++S +
Sbjct: 14169 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 14228
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
T L G +Y + +N + PV + +D P T N+ VSW+
Sbjct: 14229 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 14288
Query: 1835 PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
P + ITGY ++ + S + +TGL+ G+ Y V A
Sbjct: 14289 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 14343
Score = 122 bits (307), Expect = 3e-27
Identities = 286/1294 (22%), Positives = 482/1294 (37%), Gaps = 173/1294 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20844
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20845 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20900
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20901 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20957
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20958 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 21008
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 21009 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21067
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 21068 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21127
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 21128 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21183
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 21184 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21243
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 21244 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21300
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 21301 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21356
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 21357 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21415
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 21416 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21475
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 21476 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21535
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 21536 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21595
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
+ + + T+ GL P Y + A+N P +S ++ T +P +
Sbjct: 21596 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 21654
Query: 1638 ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
+K + Q P ++T ++ V +++ EI S+S+
Sbjct: 21655 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 21711
Query: 1688 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
V AT+ VY ++ S A+ + +P + R T+ T +T+ W
Sbjct: 21712 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21768
Query: 1745 RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
IT + ++ + K + +SYT L G +Y+ + +N
Sbjct: 21769 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 21828
Query: 1799 ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
S PVV T DAP T NS+ ++W P + I YI+ + EK
Sbjct: 21829 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 21888
Query: 1850 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT 1909
+ +V+ + T +TGL G EY +V+A +N P G + + + V
Sbjct: 21889 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVN 21947
Query: 1910 LPHPNLHGPEILDVPSTVQKTPFV--THPGYDTG 1941
P P P ++ V T + T + + P +D G
Sbjct: 21948 PPGP----PTVVKVTDTSKTTVSLEWSKPVFDGG 21977
Score = 116 bits (291), Expect = 2e-25
Identities = 282/1346 (20%), Positives = 481/1346 (35%), Gaps = 213/1346 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17848
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17849 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17895
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17896 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17951
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17952 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 18011
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 18012 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18070
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18123
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 18124 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18182
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18300
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 18301 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18354
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 18355 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18414
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 18474 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18532
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 18533 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592
Query: 1360 ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18712
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 18713 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18760
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 18761 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18816
Query: 1566 SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 18817 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18873
Query: 1613 YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
+N SG V V P AP +L +V S++ W PP ++T Y +
Sbjct: 18874 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 18930
Query: 1668 PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
K +T + + + + L Y V A + PA+ V E
Sbjct: 18931 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 18990
Query: 1724 VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
PP R + D T T TI W K E+ ITG+ V+ + G +
Sbjct: 18991 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 19048
Query: 1779 TITGLQPGTDYKIYLYTLNDNARSSP 1804
TI+GL G +Y + +N+ RS P
Sbjct: 19049 TISGLTAGEEYVFRVAAVNEKGRSDP 19074
Score = 116 bits (291), Expect = 2e-25
Identities = 149/690 (21%), Positives = 263/690 (38%), Gaps = 70/690 (10%)
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
PP ++ I ++ ++W PP L+ ++V + +S S + +
Sbjct: 23529 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 23587
Query: 1325 LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
T L G EYV V++ Y Q E R + P + D++ + T+
Sbjct: 23588 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 23646
Query: 1378 WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
W P + +TGY + R ++VP + T LT G EY + A+N
Sbjct: 23647 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23706
Query: 1434 R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
R P++ P++ V T TS+ ++W P V Y I
Sbjct: 23707 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 23766
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ + + T P T++ L G +Y V A G + P ++ +
Sbjct: 23767 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23826
Query: 1543 DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
+ P ++ + I V+ + + P+ G + + K G +K +T
Sbjct: 23827 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 23885
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
E+ I+ + +N G+ ++ V P + L++ + S+ W
Sbjct: 23886 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23945
Query: 1654 PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 23946 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 24002
Query: 1708 TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
S+P ++ VT ++PP V D T++++++SW R K + +TG+ ++
Sbjct: 24003 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 24062
Query: 1758 AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
+ ++ K + + YT+TGL P +Y+ + ND + S PVV D
Sbjct: 24063 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24121
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 24122 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 24181
Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ TI GL TEY V A S P
Sbjct: 24182 DKQFTIGGLLEATEYEFRVFAENETGLSRP 24211
Score = 113 bits (283), Expect = 2e-24
Identities = 299/1397 (21%), Positives = 486/1397 (34%), Gaps = 195/1397 (13%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 18467 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18521
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 18522 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18579
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 18580 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18638
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 18639 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 18692
Query: 905 DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 18693 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18752
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
L G+ VT L Y F++ A++ +P T AQ+ +
Sbjct: 18753 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18801
Query: 997 --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 18802 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 18858
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 18859 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18918
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 18919 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 19034
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
++ ++ +V + T L+ G EY V V + S P + +I + P
Sbjct: 19035 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 19091
Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
+L F P V + V + + V LSI
Sbjct: 19092 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 19151
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
+ V GT + +S + + G P ID +++ +S T+ W
Sbjct: 19152 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 19203
Query: 1379 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
P I+ Y I E S +R SI + LT G+EY + A N
Sbjct: 19204 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19262
Query: 1434 -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
E S ++ + P +VV AT +++L++W P V Y + Y E
Sbjct: 19263 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19322
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
+ + + + +SGL G+ Y VYA + G G S +P+ R
Sbjct: 19323 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 19380
Query: 1543 DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
D P Q +VT++ S+S+KW + +TGY V K +T
Sbjct: 19381 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19440
Query: 1599 IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
+ L Y V+A+N PS + P +V+ V D+KF V +
Sbjct: 19441 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 19499
Query: 1651 QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
+ N + G + V K G E ++ D+ +++ + V L
Sbjct: 19500 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19559
Query: 1706 KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
K+ +R L+ PP + T ++SW E G +D V
Sbjct: 19560 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 19618
Query: 1763 GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
+ + TI + + S +T L G +Y + +N P+ +D T
Sbjct: 19619 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19678
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
P++L + T S+ + W P + I+GYII+ + S V +
Sbjct: 19679 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19738
Query: 1870 ITGLEPGTEYTIYVIA-----LKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 1924
TGL G EY V A L ++ PLI + V LP P P+I+D
Sbjct: 19739 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP------VFLPSPP-SKPKIVDSG 19791
Query: 1925 STVQKTPFVTHPGYDTG 1941
T +V P +D G
Sbjct: 19792 KTTITIAWV-KPLFDGG 19807
Score = 112 bits (281), Expect = 3e-24
Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 14168 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14222
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 14223 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14269
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 14270 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14329
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 14330 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14389
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 14390 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14448
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 14449 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14508
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 14509 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14565
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 14566 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14624
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 14625 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14683
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 14684 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14742
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 14743 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14799
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 14800 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14859
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 14860 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14918
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 14919 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14978
Query: 1383 AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 14979 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 15038
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 15039 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15095
Query: 1492 QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ + T+SGL Y V A G SP S +I R +++ P
Sbjct: 15096 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15155
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 15156 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15208
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
+ ++ A NP G ++ + V P P + L T+VT
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15268
Query: 1650 AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
W PP ++ Y V+ K +T + N+A + + + V+ L+ +Y
Sbjct: 15269 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 15325
Query: 1699 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
V+ Y + + L S P V PP+ VT T+ ++ + W ++
Sbjct: 15326 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15384
Query: 1759 VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
+ QR IK + ++ Y ++GL G +Y+ + N S+P
Sbjct: 15385 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 15444
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
D P N R L T+ +S+ ++W P + ITGY+++ P ++V P
Sbjct: 15445 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 15504
Query: 1863 P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
T TITGL EY I + A+ + EP +
Sbjct: 15505 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15539
Score = 110 bits (275), Expect = 2e-23
Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
N V P P+ S E+T V+SW D G ++ + E+ + + + +
Sbjct: 10602 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 10655
Query: 769 PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
P T+ T+ + LL G+ YI N+Y IS+ + + + PDAP P V
Sbjct: 10656 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 10715
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
+V S +V W++P PIT Y + ++ + + DL G
Sbjct: 10716 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 10775
Query: 875 QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
QY + A E P + P + + ++ T V + W PP
Sbjct: 10776 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 10835
Query: 932 -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
S + GY V+ V + P S T +VTGL G TY F+V AV+ ES P
Sbjct: 10836 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 10895
Query: 989 LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
+ +L+ P + N + R A I G ++T R P
Sbjct: 10896 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 10955
Query: 1040 RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
+ +V P SK +RN SL + V +PG PP + E
Sbjct: 10956 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 11012
Query: 1098 VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
V+E + +TW G + + R + +P TS S L G
Sbjct: 11013 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 11072
Query: 1148 EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
+Y++ +V + Q P V K + PL PP +LH + D +++ W +
Sbjct: 11073 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 11129
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
R ITGY + Q + V + + C L G Y V ++
Sbjct: 11130 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 11184
Query: 1257 VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
+ + DT IP VPP +L I T+R + P P+ T
Sbjct: 11185 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 11241
Query: 1301 RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
S +K +E + + S + L T EY ++VS+ + T LD
Sbjct: 11242 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 11297
Query: 1360 ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
PTG I+ D+T T+ W P+ I + E R V S +S T
Sbjct: 11298 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11357
Query: 1415 --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+ +L G EYV + A N + +P + + + P V T + +
Sbjct: 11358 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11417
Query: 1467 SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
SW P + YY TG V + + K T GL G Y V+A
Sbjct: 11418 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 11475
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S S I I P ++ D + + W SP+ GY V
Sbjct: 11476 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 11535
Query: 1575 TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
PG + D Q + GL EY + A N GE +P L ++
Sbjct: 11536 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 11592
Query: 1629 VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
+ I P +++ VT + +++ RV+ P+ K G + K +
Sbjct: 11593 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 11650
Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
+L D V + + A + + Y + +S AQG +V L+ P + +VT+ T
Sbjct: 11651 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11709
Query: 1737 ETTITISWRTKTET----ITGFQVD 1757
+ TISW + IT F V+
Sbjct: 11710 KENCTISWENPLDNGGSEITNFIVE 11734
Score = 110 bits (274), Expect = 2e-23
Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
+T++T S +++W D Y + D + L ST N L+P +
Sbjct: 7487 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 7546
Query: 785 KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
+YI N+Y + E + S I + Q P P + ++ + W P
Sbjct: 7547 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7606
Query: 836 APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
+PITGY + P + +P + + L +Y + A + +S
Sbjct: 7607 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7666
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
T ++ ++ P P+ +D V V + WT PE + + Y ++++
Sbjct: 7667 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7721
Query: 946 LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
+ +P +++ + GL G Y F+V AV+ ES+P L ++
Sbjct: 7722 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7778
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
P L+ +N T +T ++WT P + IT Y + RR + + +K
Sbjct: 7779 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7838
Query: 1053 LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
+ L S Y + A ++S A FTT PG PPY V + T
Sbjct: 7839 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 7893
Query: 1103 -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
+ + W P G + LG R + G+ + V+ + G E
Sbjct: 7894 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 7949
Query: 1150 VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
+ ++ + + + + +P SPP +LH+ D G + ++W E++
Sbjct: 7950 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 8006
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I GY + P ++ + D + + P EY + V V S P
Sbjct: 8007 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 8066
Query: 1259 --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
IS+ ++ P P DL +I P R P S V+ S
Sbjct: 8067 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 8126
Query: 1305 ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
+KN+ A L + S A + L N L ++V +
Sbjct: 8127 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 8172
Query: 1356 TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
GL P I SDIT +S + W P G I H+ R +P ++
Sbjct: 8173 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 8230
Query: 1411 NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S T+ +L P EY + A+N G E ++P++ D P D+EV T +
Sbjct: 8231 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 8290
Query: 1464 LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
+ I+W P + Y +I GE E VP T T GL+ G +Y
Sbjct: 8291 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 8347
Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
V A G S S ID P + T ++ D SIS +
Sbjct: 8348 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 8407
Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
W+ + + + K P + G Q E
Sbjct: 8408 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8463
Query: 1600 -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
+ L+P + + +N G ++ P + + T P + F + TS+ +W PP
Sbjct: 8464 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 8522
Query: 1656 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
++ Y + K K PDS +VV+ + KY V+ Y +
Sbjct: 8523 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 8572
Query: 1708 TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
+R G V L P P + V D T ++ + W + I G+
Sbjct: 8573 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 8632
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
++ N + + +++ +++ + GL G Y + N + SP D T
Sbjct: 8633 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 8690
Query: 1812 AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
A D P R T+ ++ + W+PP I GY + + G+
Sbjct: 8691 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8750
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V + T+ + G +Y + V A+ + P
Sbjct: 8751 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 8782
Score = 110 bits (274), Expect = 2e-23
Identities = 298/1381 (21%), Positives = 508/1381 (36%), Gaps = 185/1381 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15258 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15375
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15376 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15434
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15491
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15492 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15551
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15552 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15602
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15603 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15662
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15663 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15719
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15720 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15777
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15778 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15834
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 15835 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15888
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 15889 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15946
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 15947 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 16005
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 16006 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 16064
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 16065 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16124
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 16125 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16184
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
T + GL Y V A+N +G S+P T T D S
Sbjct: 16185 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 16239
Query: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
+ ++ V G +V P+ I +++ + + AT V
Sbjct: 16240 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 16299
Query: 1702 ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
+ K+ R V L+ PP ++ T T++W+ +
Sbjct: 16300 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 16359
Query: 1751 ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
++ + +T + + +V+ S +T L G +Y + Y + +
Sbjct: 16360 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 16419
Query: 1802 SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
S PVV + DAP T +S++V W+ P + I GY++ K +K G
Sbjct: 16420 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 16479
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 1915
R G +TGL +Y V A SEP + PN
Sbjct: 16480 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN- 16537
Query: 1916 HGPEILDVPSTVQKTPFV--THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPP 1973
P+++D+ + + F+ + P YD G IQ SVG+ + TPP
Sbjct: 16538 -NPKVIDI---TRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE--------WTMCTPP 16585
Query: 1974 T 1974
T
Sbjct: 16586 T 16586
Score = 109 bits (273), Expect = 3e-23
Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6740 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6799
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6800 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6858
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6859 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6918
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6919 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6978
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6979 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 7036
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 7037 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7095
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 7096 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7155
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 7156 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7210
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 7211 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7328
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 7329 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7382
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 7383 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7439
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 7440 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7499
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 7500 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7552
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 7553 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7612
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
V + + T ++GL +Y V A+N +G +P T I
Sbjct: 7613 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7672
Query: 1633 PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
P D + P TS+ WT P ++ Y + + KTG + + +A
Sbjct: 7673 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 7729
Query: 1682 P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
++ ++ GLM +Y V A+ S P++ V E + SPPR V +
Sbjct: 7730 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7789
Query: 1735 ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
T+ T + W + IT + V+ V G + T+K T+T L G+
Sbjct: 7790 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 7847
Query: 1789 YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
Y + N +S S + D T P L + T + + W+PP+
Sbjct: 7848 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 7903
Score = 109 bits (273), Expect = 3e-23
Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)
Query: 692 VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
VTRFD S +T +G T F SP + ++ E+ S +SW
Sbjct: 18863 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18918
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ ++ + VE E Y + + T T+ I +L G Y V +E G
Sbjct: 18919 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975
Query: 799 QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
L T++ PP P T+ V + ++W +P++ ITGY V +
Sbjct: 18976 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 19032
Query: 851 GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
GS + T+S L G +Y + AV E S P VI ++ P
Sbjct: 19033 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 19090
Query: 905 DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
+V P V+ + +K+ + + A +R D GQ L ++ +
Sbjct: 19091 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 19139
Query: 960 TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
+ VT LS V Y + S G + P+T + P ++ + ++
Sbjct: 19140 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19199
Query: 1014 LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
+ W PP QI+ Y V + V +V++ ++ L SEY +
Sbjct: 19200 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19257
Query: 1068 AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
A ES + PG P T++T+++TW IG+
Sbjct: 19258 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19317
Query: 1117 LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
L + +A + + +D+ + VSGL G+ Y VY + G+ +
Sbjct: 19318 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19376
Query: 1171 VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
P PP TN+ ++ + D G + ER PD G + TN
Sbjct: 19377 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 19434
Query: 1216 QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
Q+ + DQ + D++S E + VKDD E V D
Sbjct: 19435 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 19493
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
I+ + G ++WA I++ E+ A I +DN
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 19539
Query: 1323 VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
+LT +YV+++ +V + + K G P G ++ + +TA ++
Sbjct: 19540 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 19597
Query: 1377 HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
W P+ A I Y + + H + E + S +T L G EY+ + +
Sbjct: 19598 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 19655
Query: 1432 NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
N E + TV P LE+ + T S+ + W P + Y I
Sbjct: 19656 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19715
Query: 1482 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
E V+ P +GL+ G +Y VYA G S P+ + P+ I
Sbjct: 19716 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 19774
Query: 1541 EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
+ PS+ ++ D +I++ W+ +P+TGY V K+ KT
Sbjct: 19775 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 19833
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
TE TI GL EYV V + N PS S P + P ++++ T +
Sbjct: 19834 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 19893
Query: 1645 PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
S T P +R R P +T + + S ++ + +
Sbjct: 19894 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 19947
Query: 1696 TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
KY +++ ++ L++ VV L+ PP V D T+ + +SW +
Sbjct: 19948 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 20004
Query: 1752 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
+ ++ A+ + + T + SY +T LQ G Y + N+ P
Sbjct: 20005 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 20064
Query: 1812 AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
I P L + + +S+ ++W P +RI Y+++ + G + V
Sbjct: 20065 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 20122
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
T ++GL +EY V A S+P
Sbjct: 20123 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20153
Score = 105 bits (262), Expect = 5e-22
Identities = 346/1650 (20%), Positives = 609/1650 (36%), Gaps = 262/1650 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8910 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8967
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8968 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 9014
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 9015 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9074
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 9075 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9130
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 9131 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 9191 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9247
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9248 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9307
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9308 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9363
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 9364 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9423
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 9424 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9479
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9480 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9539
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 9540 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9598
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 9599 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9657
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 9658 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9717
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 9718 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9777
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 9778 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9837
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 9838 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9897
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 9898 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9954
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
N KT ++ P + TI L EYV + AQN G +PL T +
Sbjct: 9955 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010
Query: 1632 IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
+P AP + VT S++ W P +TGY + + K+ T K +N P +
Sbjct: 10011 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 10068
Query: 1686 -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
S V+GL+ + Y+ VYA+ +L S PA T + ++PP +V
Sbjct: 10069 MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 10124
Query: 1733 TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
TD T+++ + W + +TG+ V+ G+ ++ +VR +TGL+ G
Sbjct: 10125 TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 10183
Query: 1787 TDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1842
YK + +N P VI+ + +P +L+ A+ + ++V RI
Sbjct: 10184 AFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGVIRIIA 10241
Query: 1843 YIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE----PLI 1896
Y+ G PP V R EATI T + +KN Q+S L+
Sbjct: 10242 YV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQGVYSLL 10291
Query: 1897 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----PGTSGQ 1952
+ + E + + + ++LDVP V TPF+ H T +L P G
Sbjct: 10292 AKNEAGERKKTIIV--------DVLDVPGPV-GTPFLAH--NLTNESCKLTWFSPEDDGG 10340
Query: 1953 QPSVGQQMIFEEHGFRRTTPPTTATPIRH--------RPRPYPPNVGEEIQIGHIPREDV 2004
P + +I + RR P T T R + + Y + E IG P +
Sbjct: 10341 SP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 10399
Query: 2005 DYHLYPHGPGLNPNASTGQEALSQT----TISWAP--FQDTSE---YIISCHPVGTDEEP 2055
L P P E T T++W P + SE Y++ +GT++
Sbjct: 10400 SEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH 10459
Query: 2056 LQFRVPGTSTSATLTGLTRGATYNIIVEAL 2085
S T+ GL G TY V A+
Sbjct: 10460 KVTNDNLLSRKYTVKGLKEGDTYEYRVSAV 10489
Score = 105 bits (261), Expect = 7e-22
Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 9924 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9983
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 9984 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 10043
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 10044 TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10101
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 10102 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10161
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 10162 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10221
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 10222 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10275
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 10276 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10335
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 10336 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10395
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 10396 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10454
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 10455 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10511
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
PPT +R T R + P P + S K+E DV E +
Sbjct: 10512 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10562
Query: 1315 SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
+P+ A+ G VV +S + + + G P G + F ++T
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 10620
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
+ + W P G +I ++ ++ +P ++ + ++ L G +Y+
Sbjct: 10621 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 10679
Query: 1427 SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
I A N S L+ V D P V T S L++W+ P
Sbjct: 10680 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 10739
Query: 1472 -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
++ R+ R+T P +F VP L G Y V A
Sbjct: 10740 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 10787
Query: 1523 GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
G GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 10788 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 10844
Query: 1576 TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
K G + P+ +T+ + GL+ Y V A N +GES P +
Sbjct: 10845 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 10898
Query: 1633 PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
P P +K P L A G +R++ P K KE AP +
Sbjct: 10899 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10958
Query: 1686 SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
+ V+ V +K E+ +Y+L ++ S+ V L+ PPR V++
Sbjct: 10959 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 11016
Query: 1736 TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
+ + ++W+ + IT + V+ V + +P+ T K +S+ L G Y
Sbjct: 11017 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 11074
Query: 1790 KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
+ N R V +D P +L + + + W P +
Sbjct: 11075 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 11134
Query: 1839 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
ITGY+++Y++ G+ ++ + E +TGL+ G Y V K+E ++G
Sbjct: 11135 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 11184
Score = 102 bits (255), Expect = 3e-21
Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10330 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10388
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10389 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10436
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10437 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10496
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10497 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10557 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10614
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10615 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10670
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10671 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10730
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10731 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10790
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 10791 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10848
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 10849 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10908
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 10909 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10967
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 10968 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 11013
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 11014 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11072
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 11073 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11131
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 11132 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11189
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 11190 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11241
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 11242 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11293
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 11294 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11350
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
+G +T++ I LQ EYV V A+N G PL T + P+P T +
Sbjct: 11351 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11410
Query: 1644 TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
T + + WT P +TGY + +E TG +N P + V+GL Y
Sbjct: 11411 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 11468
Query: 1699 EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
E V+A S+P+ ++ PP ++ D + T + W TK
Sbjct: 11469 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 11527
Query: 1749 ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
I G+ V+ G R K ++ ++ + GL G +Y+ + N P
Sbjct: 11528 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11585
Score = 102 bits (255), Expect = 3e-21
Identities = 255/1289 (19%), Positives = 459/1289 (35%), Gaps = 229/1289 (17%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17613 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17670
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17730
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17731 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17781
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17782 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17841
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17842 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17900
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 17901 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17956
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 17957 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 18015
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 18016 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 18041
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 18042 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 18087
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 18088 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 18110
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 18111 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 18166
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 18167 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 18226
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 18227 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 18281
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 18282 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 18341
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 18342 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 18401
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 18402 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18461
Query: 1605 TV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
V +Y++ + N G + V P P + LK T VT W
Sbjct: 18462 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18519
Query: 1654 PPNVQLTGYRVR--VTPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYA 1704
PP +Q G + + K +T + +++ + + V+ L+ +Y V+ Y
Sbjct: 18520 PP-LQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 18578
Query: 1705 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVP 1760
+ + L S P + PP V+ T+ ++ ++W + I G+ ++
Sbjct: 18579 IGEPLESGPVT-ACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD 18637
Query: 1761 ANG--QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDAST 1811
G T + D+R +TGL G Y+ + N P DA
Sbjct: 18638 KEGVRWTKCNKKTLTDLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY 18696
Query: 1812 AIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV-- 1865
PSN + T+ +S+ ++W P A + GY+++ K + P G+
Sbjct: 18697 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQG 18755
Query: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ T+T L+ TEY + A+ + EP
Sbjct: 18756 KQFTVTKLKENTEYNFRICAINSEGVGEP 18784
Score = 102 bits (254), Expect = 4e-21
Identities = 337/1641 (20%), Positives = 581/1641 (35%), Gaps = 234/1641 (14%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 17208 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17266
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 17267 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17315
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 17316 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17375
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 17376 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17432
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 17433 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17492
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 17493 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17545
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 17546 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17602
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 17603 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17660
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 17661 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17719
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 17720 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17779
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 17780 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17834
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 17835 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17894
Query: 1258 PIS--DTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEED 1310
P+ D + A PP P + T++ + + W P + ++V P K E
Sbjct: 17895 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEK 17953
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
+ ++ S NAVV T L G EY V + E+ G P + +
Sbjct: 17954 WSIVAESKVCNAVV-TGLSSGQEYQFRVKAYNEK------------GKSDPRVLGVP-VI 17999
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPE-----HFSGRPR------EDRVPHSRNSITLTNLT 1419
A T+ + + Y I+ + GRPR +D P + + T
Sbjct: 18000 AKDLTIQ-PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEET 18058
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVA---------------ATPTSL 1464
T V+ I N + + ++ +L V+ + +
Sbjct: 18059 -ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 18117
Query: 1465 LISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
+ISW+ PA T + Y + +T + + +++T I+ LK G +Y ++A
Sbjct: 18118 VISWEPPAYTGGCQISNYIVEKRDTT-TTTWHMVSATVARTTIKITKLKTGTEYQFRIFA 18176
Query: 1521 VTGRGDS-PASSKPISINYR-TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S P SK + + Y E P VT + + + V+W + + GY +
Sbjct: 18177 ENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHL 18236
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
KN K T+ GL +EY V A+N G +P +
Sbjct: 18237 EQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 18296
Query: 1635 PTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSS 1686
P D + +T +++ +W P ++TGY V MK +
Sbjct: 18297 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18356
Query: 1687 VVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR--------VTDA 1735
VSGL+ +YE V A S P+ G +T + + P + V A
Sbjct: 18357 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 18416
Query: 1736 TET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYL 1793
ET + R K + D +T + IK ++ T+ TD Y+
Sbjct: 18417 GETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475
Query: 1794 YTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARITGYIIK 1846
L++ +S P+ + P L+ T ++W PP A I+ YII+
Sbjct: 18476 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 18535
Query: 1847 YEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQ 1906
+ V + +T L PG EY V+A+ EPL + P
Sbjct: 18536 KRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL------ESGPV 18588
Query: 1907 LVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHG 1966
P+ P +V + + + VT G ++ G ++ ++ G
Sbjct: 18589 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR--------DKEG 18640
Query: 1967 FRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH----LYPHGP 2013
R T T T +R R Y V E +G V Y LYP GP
Sbjct: 18641 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGP 18700
Query: 2014 GLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRVPG-TSTSA 2067
NP + + S +++W+ P D Y++ DE G
Sbjct: 18701 PSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQF 18758
Query: 2068 TLTGLTRGATYNIIVEALKDQ 2088
T+T L YN + A+ +
Sbjct: 18759 TVTKLKENTEYNFRICAINSE 18779
Score = 101 bits (252), Expect = 7e-21
Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21861 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21919
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21920 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21967
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21968 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 22027
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 22028 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22087
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 22088 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22146
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 22147 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22202
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22203 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22261
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22262 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22319
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22320 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22374
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22375 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22434
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22435 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22494
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 22495 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22551
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 22552 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22610
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22668
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 22669 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22726
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 22727 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22786
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 22787 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22843
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 22844 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22891
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
+ YVV+ V A N G ES+P+V TIP+P + T +
Sbjct: 22892 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22951
Query: 1649 SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
QWT P +++ Y V K + ++ + D + + V+ LM Y+
Sbjct: 22952 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 23008
Query: 1701 SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
V A+ S P A ++ E PP RV D T+ +I+++W
Sbjct: 23009 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 23057
Score = 101 bits (251), Expect = 1e-20
Identities = 277/1345 (20%), Positives = 482/1345 (35%), Gaps = 189/1345 (14%)
Query: 692 VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
V R+D +T T ++ T + +P + VTEIT S ++W +
Sbjct: 16698 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 16757
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
+ + VE E Y + + S I L G Y V +E G
Sbjct: 16758 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 16814
Query: 803 LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
+ + P P TVD V S+ + W++P+ I Y ++ +E
Sbjct: 16815 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 16873
Query: 860 ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
E A +++L G +Y + AV E S P +VI+ + S
Sbjct: 16874 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16933
Query: 905 DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
+V +DL+ +EV K TI WT D +P+ Q I+
Sbjct: 16934 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 16976
Query: 962 AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
++T LS T+ Y A G+++ + K D P ++F + + ++
Sbjct: 16977 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 17036
Query: 1015 VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
+ W PP QIT Y + T + + + + L+ +EY + A
Sbjct: 17037 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 17096
Query: 1071 --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
G ES + +PG P+ T +++ ++VI W +P IG+ L
Sbjct: 17097 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 17156
Query: 1120 RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
+ + + + D+ L G+EY + + V + + + +
Sbjct: 17157 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 17215
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
P P + ++ N +T+ W + ITGY + P S V+
Sbjct: 17216 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17271
Query: 1226 HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
++ T L+ Y V K + PI+ + +P + P D
Sbjct: 17272 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 17328
Query: 1273 LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
N G +T R V P P+I+ K E+ A I +D +L
Sbjct: 17329 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 17381
Query: 1326 -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
+ G +Y++ S+V +S P+ + P G + + +T+ ++ W +P
Sbjct: 17382 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 17439
Query: 1384 TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR----- 1434
G I H+ + + R V NS+ +T L G EYV I+A+N
Sbjct: 17440 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17499
Query: 1435 -EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
E +P+L+ + P+ LEV S+ + W+ P I Y E S ++
Sbjct: 17500 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 17559
Query: 1493 EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
+ T ++GL +Y V A G S P ++ Y+ +
Sbjct: 17560 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 17617
Query: 1545 PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG-PTKTKTAGPDQTEMTI 1599
P+ + D NSI++ W S + GY V + T G T I
Sbjct: 17618 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 17677
Query: 1600 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
L EY + V A N G + T+V P D + L ++ V
Sbjct: 17678 SKLTEHQEYKIRVCALNKVGLGEA---TSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 17732
Query: 1660 TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
G R+ K P EI + + + V + + T+ + + L
Sbjct: 17733 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 17792
Query: 1706 KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
+++ S+ A V L+ PP+ V + + + + W + + +D +
Sbjct: 17793 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 17852
Query: 1762 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
+ + K S+ + L G Y + N+ PV +DA A + PS
Sbjct: 17853 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 17912
Query: 1818 --NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
L ++ T SL+ W+ P +R+ GY+++ + G+ +V + V A +T
Sbjct: 17913 KVTLTDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVT 17968
Query: 1872 GLEPGTEYTIYVIALKNNQKSEPLI 1896
GL G EY V A KS+P +
Sbjct: 17969 GLSSGQEYQFRVKAYNEKGKSDPRV 17993
Score = 98.6 bits (244), Expect = 6e-20
Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 18973 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 19030
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 19031 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19081
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 19082 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19138
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 19139 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19195
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 19196 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19255
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 19256 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19309
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 19310 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19368
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 19369 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19426
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 19427 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19477
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 19478 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19534
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 19535 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19593
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 19594 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19651
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 19652 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19711
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 19712 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19770
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 19771 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19828
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 19829 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19884
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19940
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 19941 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19995
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 19996 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 20054
Query: 1621 SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
P +T P+P + L T ++ S+S W P ++ Y V K +
Sbjct: 20055 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20114
Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
+K S+ VVSGL ++Y V+A S P + ++ L E + PP
Sbjct: 20115 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 20172
Query: 1729 ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
R + I IS + + F + N ++
Sbjct: 20173 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 20232
Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
++ D Y IT K ++ + VV+D P + + T S
Sbjct: 20233 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 20281
Query: 1829 LLVSWQPPR----ARITGYII 1845
+ + W+PP+ +++T YI+
Sbjct: 20282 VTLKWEPPKYDGGSQVTNYIL 20302
Score = 98.2 bits (243), Expect = 8e-20
Identities = 256/1304 (19%), Positives = 463/1304 (35%), Gaps = 171/1304 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13201 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13260
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13261 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13308
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13309 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13366
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13367 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13418
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13479 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13530
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13531 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13589
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13590 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13647
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13648 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13707
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13708 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13768 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13825
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 13826 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13883
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 13884 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13941
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 13942 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 14001
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 14002 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 14057
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 14058 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 14114
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 14115 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 14174
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 14175 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14234
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTTI-----PAPTDL-KFTQVTPTSLSAQWTPP--- 1655
EY+ V A N G+ +P+ V + P P + + + VT + + W P
Sbjct: 14235 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14293
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++TGY V K+ ++ I V+GL + YE V A P+
Sbjct: 14294 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14353
Query: 1715 QGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1765
+ + L PP VTD T+ + +++W ITG+ V+ +
Sbjct: 14354 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEA 14413
Query: 1766 PIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
I+ T +R + + LQ Y + +ND P VI
Sbjct: 14414 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14457
Score = 97.4 bits (241), Expect = 1e-19
Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
T +VT L G Y F+V V+ +PL + LD PT+L+ + T ++
Sbjct: 19635 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19694
Query: 1014 LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
+ W+ P + +I+GY + RR + V V+K P+ +L+ S
Sbjct: 19695 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 19748
Query: 1061 EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
EY V G ++ SP P P + +TTI I W A
Sbjct: 19749 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 19808
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
P G+ + + S + + S G+ +SGLT G EYV+ ++ + D +
Sbjct: 19809 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19868
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
P + K P ++ E V +TV + P++ + + P +
Sbjct: 19869 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 19923
Query: 1218 GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + + ++S T +N + +Y +++ V S+ + ++ PPT++
Sbjct: 19924 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 19981
Query: 1276 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
++ ++ ++W P + +PVKN E + +S ++N + +T
Sbjct: 19982 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 20034
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
NL G Y VS E P ++ + P + + I+ +S ++ W+ P
Sbjct: 20035 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 20094
Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
G RI H+ + +++ V + T ++ L +EY + A N S
Sbjct: 20095 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20153
Query: 1438 -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
P+LI +Q ++ P V A + D P ++T G
Sbjct: 20154 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 20210
Query: 1488 N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
F + TI+ LK V Y +T S + I+I +D+P
Sbjct: 20211 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 20266
Query: 1547 Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
+ ++D+ + S+++KW P S VT Y + + T+ +A +T M
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 20325
Query: 1599 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
+ L EY + A+N G S + VT T P P + T VT S++ W
Sbjct: 20326 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 20385
Query: 1653 TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
P + GY + + + K L ++ V+ + YE VYA
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 20445
Query: 1709 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
+P+ V ++ PPR R+TD ++ ++++SW+ ITG+ V+ +P
Sbjct: 20446 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 20505
Query: 1761 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
T T + + + I+GL + Y+ ++ N + + V+ T ID+
Sbjct: 20506 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 20561
Score = 96.3 bits (238), Expect = 3e-19
Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 7193 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7251
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 7252 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7311
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 7312 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7371
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 7372 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7431
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 7432 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7490
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 7491 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7550
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 7551 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7610
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 7611 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7669
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 7670 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7726
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 7727 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7786
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 7787 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7845
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7905
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 7906 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7965
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 7966 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 8013
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 8014 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8069
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 8070 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8129
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
M + + +E SV A +N G + + V +P P D+K + +T +
Sbjct: 8130 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8189
Query: 1647 SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
S W PP T V + + G I + + S V L+ +Y V
Sbjct: 8190 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8249
Query: 1704 ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
A+ ++ G L+N PP V + T +TI+W+
Sbjct: 8250 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 8304
Query: 1750 TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
I G+ ++ + A G+ +R + + +YT GL+ G +Y+ + +++ +R+
Sbjct: 8305 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 8363
Query: 1803 SPVVIDASTAIDAP 1816
+P A IDAP
Sbjct: 8364 TPPT-KAVDPIDAP 8376
Score = 94.4 bits (233), Expect = 1e-18
Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 12395 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12452
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 12453 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12500
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 12501 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12560
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 12561 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12620
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 12621 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12680
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 12681 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12732
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 12733 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12792
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 12793 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12850
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
L EY+ + A+ SP K T T P PP E VT++T+ + W P
Sbjct: 12851 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12908
Query: 1110 APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
G K+ G + + AP ++ + +GL +Y +
Sbjct: 12909 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12966
Query: 1152 -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
TI D + K + + TN+ L+A + TVSW++
Sbjct: 12967 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 13026
Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
T P G + + ++ CT + N +Y ++
Sbjct: 13027 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13071
Query: 1254 KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
K S I ++ PP ++ + D ++W PP ++TN++V + +
Sbjct: 13072 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 13129
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
A++S + + + L+ G EY + + + P+ K D P D
Sbjct: 13130 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 13189
Query: 1366 -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
S+IT + TV W P + ITGY + + +R P ++ T L
Sbjct: 13190 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13249
Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
GTEY + A+N + P G+ S S P +V T +S+ +SW
Sbjct: 13250 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13304
Query: 1469 DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
PA + Y + ++ V+ +P + K+ ++GL Y VYAV
Sbjct: 13305 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13363
Query: 1523 GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
G D P P I E + + ++ T + ++++ PV G
Sbjct: 13364 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13420
Query: 1578 PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
+ P G D T + E + +Y++++ +N G+ + + V
Sbjct: 13421 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13478
Query: 1630 TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
P P ++ +++ S W PP + + Y V+ E+ +
Sbjct: 13479 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 13537
Query: 1685 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
+S V+ L Y V+A + P + V + P +V ++++ +I
Sbjct: 13538 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 13597
Query: 1743 SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
W+ I G+ VD + + QR +K Y+ L G +Y + N+
Sbjct: 13598 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 13655
Query: 1799 NARSSP--VVIDASTAIDAP 1816
N +P + + A + AP
Sbjct: 13656 NGEGTPSEITVVARDDVVAP 13675
Score = 94.0 bits (232), Expect = 2e-18
Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)
Query: 710 TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
TV+ TP P+ E +I +S + W D + Y L ++ + +++
Sbjct: 8490 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 8546
Query: 767 DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
+ ST ++ L+ G++Y+ V + G +++ PDAP P V
Sbjct: 8547 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8606
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
+ V S++V+W+ P+ +PI GY + E +ST + + L G+
Sbjct: 8607 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 8663
Query: 877 NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
+T ++ V + P + D + P P + + + + + W PP
Sbjct: 8664 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 8723
Query: 932 --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ GY VD ++ N +++ + + T E+ G Y +V AV+ E
Sbjct: 8724 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 8780
Query: 987 KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
P Q T +LD T+ + WT ++
Sbjct: 8781 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 8840
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
R+ + NVG + K LR + Y ++ G++ + V
Sbjct: 8841 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 8888
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
F P + P T ++ W+ + GF + + ++ + + ++
Sbjct: 8889 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 8946
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
++GL G EY + +V+ + P V V PL PPT+ + E
Sbjct: 8947 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 9004
Query: 1188 TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
T +T+ W+ + I GY I + + + + +S +NL Y
Sbjct: 9005 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 9061
Query: 1245 VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
V V + ES +P++ I PPT ++ DT++V P I D+T
Sbjct: 9062 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 9121
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
+ E V E P+D + + +E +S +V E + + +
Sbjct: 9122 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 9178
Query: 1357 GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
G P + +DI A S + W AP G I H+ + + R
Sbjct: 9179 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 9237
Query: 1402 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
+ + + ++ + L P +Y + A+N S + + D P
Sbjct: 9238 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 9297
Query: 1452 RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
+V+A T S+L+SW P + Y + E G +P+ + + G +
Sbjct: 9298 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 9357
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
+ L GV Y A+ G P S S P ++ + PS +V D +S
Sbjct: 9358 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 9415
Query: 1558 ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
IS+ W P + SP+ GY V + G T K PD+ T E + P ++ Y
Sbjct: 9416 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 9472
Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
V A N +GES+P T IPA TD++ + AQ V G ++R+
Sbjct: 9473 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 9527
Query: 1667 ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
TPK E G K ++ A +SS +++ + + S+
Sbjct: 9528 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 9587
Query: 1704 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
A K+ + A V ++ PP+ +V+D T + +SW+ + I G+ ++
Sbjct: 9588 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 9646
Query: 1760 PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
+G+ + + PD S T + L Y + N PV I +TA D
Sbjct: 9647 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 9704
Query: 1816 -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
P L+ T N++ +SW+PP+ + +T YI++ ++ G+ +
Sbjct: 9705 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 9764
Query: 1864 GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
V E T+ L G EY V A+ S+P
Sbjct: 9765 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9797
Score = 93.6 bits (231), Expect = 2e-18
Identities = 266/1257 (21%), Positives = 449/1257 (35%), Gaps = 180/1257 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 21115 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21174
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 21175 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21233
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 21234 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21288
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 21289 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21346
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 21347 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21406
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 21407 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21466
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 21467 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21526
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 21527 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21584
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 21585 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 21640 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21694
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 21695 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21751
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 21752 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21809
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 21810 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21869
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 21870 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21917
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P+ ++VTD ++S++W
Sbjct: 21918 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21977
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 21978 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 22037
Query: 1627 T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
T AV + AP D F Q A +++L Y+ R TP + P
Sbjct: 22038 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 22092
Query: 1678 INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
++L D ++ S L V A KY ++V ++ S+ V L+ PP
Sbjct: 22093 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 22149
Query: 1730 ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
D T + T+ W I + V+ A+ ++ + K + + + L
Sbjct: 22150 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 22209
Query: 1786 GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
G Y + +N+ P I A+ P L + T+ +S +++W P
Sbjct: 22210 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 22269
Query: 1838 ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+RITGY+++ + GS V T+ L TEY V A + SEP
Sbjct: 22270 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 22324
Score = 92.8 bits (229), Expect = 3e-18
Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20263 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20322
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20323 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20380
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20381 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20439
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20440 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20498
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20499 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20555
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20556 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20615
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20616 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20675
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20676 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20732
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 20733 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20792
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 20793 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20852
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 20853 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20908
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 20909 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20968
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 20969 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 21024
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 21025 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21079
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 21080 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21137
Query: 1616 NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
N G +P T +PAP DL T TS+ WT P+ +T Y V
Sbjct: 21138 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21197
Query: 1668 PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
K E+T I+ + + VS L + E V+A + S P G +T E +
Sbjct: 21198 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 21254
Query: 1726 PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
P + V + + ++ K + + D +P ++ +T
Sbjct: 21255 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 21314
Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
S + G Y + L DNA V + PS +RF +S++
Sbjct: 21315 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 21370
Query: 1831 VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
+SW P IT Y I+ + ++V T + L EY V A
Sbjct: 21371 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 21429
Query: 1887 KNNQKSEPLI 1896
S+PL+
Sbjct: 21430 NRYGVSQPLV 21439
Score = 91.3 bits (225), Expect = 1e-17
Identities = 267/1256 (21%), Positives = 445/1256 (35%), Gaps = 161/1256 (12%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
S+ + T +S ++SW EY + +G Q + + I ++ ++
Sbjct: 21165 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 21223
Query: 787 IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
V +++ E+ L ++ T + P VD D + VR Y+
Sbjct: 21224 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 21283
Query: 843 IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
PS+ L L E T N +TLS ++ + +N V
Sbjct: 21284 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 21343
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
I T G P P ++F E+ V + W PE +T Y ++ +
Sbjct: 21344 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21399
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
++R TF +V L Y F+V A + S+PL A+ ++ P
Sbjct: 21400 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 21458
Query: 1005 FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
+ N T + + W P +++TG+ + ++ N P S +Y L
Sbjct: 21459 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 21518
Query: 1059 ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
+Y + A SP FT P P +VT TI + W P R G
Sbjct: 21519 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 21578
Query: 1116 K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
+ QG E R V + + V+GL+PG Y + I I
Sbjct: 21579 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 21624
Query: 1167 VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
V +SPP+ +E P+ G++ S E + R
Sbjct: 21625 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21684
Query: 1212 PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
T + G +E+ ++ D T + + VYTV+ S V +
Sbjct: 21685 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
DT V P +RFTNI + M + W P + +T++++ ED
Sbjct: 21745 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 21801
Query: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
E + S A+ L N G EY VS+V + PL Q T D+P +
Sbjct: 21802 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21855
Query: 1367 SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
S+IT NS T+ W P + I Y + + + + + P S +T LT G
Sbjct: 21856 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21915
Query: 1422 TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
EY ++A N P LI + V+ P ++V + T++ + W P
Sbjct: 21916 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21975
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
I Y + + ++ + K+ T++ L+ G +Y V A+ G+GDS
Sbjct: 21976 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 22035
Query: 1528 --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
+ K + E+D + + T V S++ ++ T V + P +
Sbjct: 22036 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 22095
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
+ +T+E ++ +N SG V P P + F V
Sbjct: 22096 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 22155
Query: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
T S + W P + G R+ EK + I+ V+ L Y
Sbjct: 22156 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22214
Query: 1700 VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
V A+ + P + + E +PPRR V D ++++ ++W ITG
Sbjct: 22215 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 22274
Query: 1754 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
+ ++ ++ + ++T+ L T+Y+ + ND S P +S I
Sbjct: 22275 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22333
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1866
P P + L IT +I K GSP VP RP P VT
Sbjct: 22334 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22375
Score = 90.1 bits (222), Expect = 2e-17
Identities = 140/634 (22%), Positives = 237/634 (37%), Gaps = 93/634 (14%)
Query: 1358 LDSPTG---IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHS 1409
LDSP + S +T T+ W P+ A IT Y + R + E P
Sbjct: 22833 LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTL 22892
Query: 1410 RNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S +T L EY+ + A+N E P++ T+ P E V
Sbjct: 22893 --SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH 22950
Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT-----------------IS 1506
++I W P E+ G + + + V + + ++
Sbjct: 22951 IIIQWTKP------------ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVT 22998
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWL 1563
L G DY V AV G+S S I+ R PS +V D +SIS+ W
Sbjct: 22999 SLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 23058
Query: 1564 P----SSSPVTGYRVTTTPKNGPGPTKTKT-AGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
+ + GY + K+ + T A TE T+ L+ +Y V A N
Sbjct: 23059 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 23118
Query: 1619 G---------ESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1669
G E +P+ + + + DLK T S + V ++G V
Sbjct: 23119 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM---VSVSGRPPPVITW 23175
Query: 1670 EKTG---PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS--RPAQGVVTTLENV 1724
K G + I +S S+++ + +Y+ Y ++ S + A +V +
Sbjct: 23176 SKQGIDLASRAIIDTTESYSLLIVDKV--NRYDAGKYTIEAENQSGKKSATVLVKVYDTP 23233
Query: 1725 SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
P +V + + ++TI+W T + + V+ A + T K Y I
Sbjct: 23234 GPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRI 23293
Query: 1781 TGLQPGTDYKIY-----LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP 1835
+GL GT Y +Y + + +S V+ + + P+ L + T +++ ++W+
Sbjct: 23294 SGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEK 23352
Query: 1836 PR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1891
P +R+TGY+++ K G+ V +P V E T+T L G +Y + A
Sbjct: 23353 PLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGV 23412
Query: 1892 SEP-----LIGRKKTDELP--QLVTLPHPNLHGP 1918
SEP + + LP L T+P +H P
Sbjct: 23413 SEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 23446
Score = 89.7 bits (221), Expect = 3e-17
Identities = 131/594 (22%), Positives = 227/594 (38%), Gaps = 77/594 (12%)
Query: 1414 TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
T+T L G EY+ + A N ++P+ + V P ++ + +
Sbjct: 6844 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 6903
Query: 1466 ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
++W+ P + Y I + TV +AT++ + G +Y+ V A
Sbjct: 6904 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 6963
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S+ + I++PS + +D +S+ +KW P SP+ GY +
Sbjct: 6964 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 7023
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
+ + + + GL+ +Y+ V A+N +G S P + I
Sbjct: 7024 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 7077
Query: 1635 PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
P V PT LSA + PN V TGY R T +TG +
Sbjct: 7078 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7137
Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
+ + +V+S + + + +Y LK + G V + S P+ + D
Sbjct: 7138 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 7194
Query: 1736 TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
T+ ++ ++W + +TG+ V+ + +T + +T+ L G +Y
Sbjct: 7195 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 7254
Query: 1792 YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
+ N P +D +T D P N+++ T NS+ ++W PP+ +RI
Sbjct: 7255 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 7314
Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
GYI++ GS P T+ +TGLE G Y V AL S+P +
Sbjct: 7315 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRP 7370
Query: 1901 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQP 1954
T+E+ + T P + LDV T G I+LP T +P
Sbjct: 7371 TEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTGKP 7413
Score = 89.4 bits (220), Expect = 4e-17
Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)
Query: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
S P E+ E P+ P S P+ + K+I + W+P KN +G E G
Sbjct: 7965 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 8022
Query: 662 -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
+NS IK LK GVV + + + ++ G E + + P
Sbjct: 8023 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 8081
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
T+ ET + S+ + + V VS + L+ + D
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 8134
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ + +P + I + ++ G + ++ P D + +S
Sbjct: 8135 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8192
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
+ W P+ PI Y + + + + E S T+ DL P +Y + AV
Sbjct: 8193 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 8252
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
+ + ++ P D++ T +TI W PP S + GY ++
Sbjct: 8253 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 8312
Query: 941 VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
I GE + +PI T GL G Y F+V A + S+P A
Sbjct: 8313 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 8366
Query: 995 TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
TK +DAP T+L+ V D L + W I +
Sbjct: 8367 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 8425
Query: 1032 GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
L RR Q + V P + + N + Y + + G
Sbjct: 8426 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 8485
Query: 1074 ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
++P V T PG I ++ +T+++ W P G + + E +
Sbjct: 8486 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 8541
Query: 1134 DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
DS IVV+ L G EY++ ++ + P V+K + P PP
Sbjct: 8542 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 8600
Query: 1179 -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
+ + + + + V W + I GY + N + + + + + D
Sbjct: 8601 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 8659
Query: 1236 NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
L GL Y V + P SD P PP P R T+ T+ + W P
Sbjct: 8660 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8719
Query: 1290 PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
P ++ + V V E + + G +Y + VS+V E
Sbjct: 8720 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8779
Query: 1347 STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
P + T + P ++ + + G +R P +GRP
Sbjct: 8780 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 8830
Query: 1405 RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
+V ++ + + N+ +E ++ I A N + V
Sbjct: 8831 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 8888
Query: 1448 SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
DVP DL+ V L++W P E G S + F +
Sbjct: 8889 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 8936
Query: 1500 ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
+S I+GL G +Y V A G P P+ I +D
Sbjct: 8937 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 8992
Query: 1545 PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
P ++ T+ ++I++ W SP+ GY + + P + T +E
Sbjct: 8993 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 9052
Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
L Y V A N GES+P ++P ++ +V PT LS + V
Sbjct: 9053 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 9105
Query: 1658 QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
+ G V + P + TG PM +I + + + + + + TK EVS V
Sbjct: 9106 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163
Query: 1703 YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
K T T + + + NV SPPR VTD + ++W +
Sbjct: 9164 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 9223
Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
IT + +D A+ + + + Y I L P Y+ + Y ++D +S
Sbjct: 9224 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 9283
Query: 1804 PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
VVI D P + LA T S+LVSW PP + ITGY ++ + GSP V
Sbjct: 9284 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 9343
Query: 1859 PRPRPGVTEATITGLE 1874
R +T+ + G+E
Sbjct: 9344 --SRAPITKVGLKGVE 9357
Score = 89.4 bits (220), Expect = 4e-17
Identities = 289/1431 (20%), Positives = 507/1431 (35%), Gaps = 177/1431 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ P++ P ++ + + NS + W P+ S I +YI+ +
Sbjct: 16808 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 16865
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K+S +W E L + I L G Y +++++ + G + S + P+
Sbjct: 16866 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 16916
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E + S V + +S T++ + L +
Sbjct: 16917 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 16975
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
L T S+ G +Y + V + G+++ + PD P P D V
Sbjct: 16976 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 17033
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
SI + W+ P IT Y + + ++ ++ ++ L+ G +Y I+
Sbjct: 17034 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 17093
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
A EN+ ++ + P P F ++ + I W P S V G
Sbjct: 17094 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 17151
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
Y ++ N I +T + L G+ Y F+V+A V G+ SK
Sbjct: 17152 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 17211
Query: 994 TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
D P + + + + ++WT P + ITGY + G+ + + +
Sbjct: 17212 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17271
Query: 1049 -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
+++ + L Y ++A G P +TG T P S+ P + +
Sbjct: 17272 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 17328
Query: 1101 TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
T +V + P P I + G + + + T ++V
Sbjct: 17329 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17388
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
Y ++ + P+ KV+ PP + +++W + DI+
Sbjct: 17389 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 17448
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
Y + T+ + V + T L G EY V+ Y V + ES P+
Sbjct: 17449 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17506
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
+ ++P PP L TNI D+M V W P S + + ++ + + +
Sbjct: 17507 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 17564
Query: 1318 P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
+D + +T L EY VS + E +P K PT
Sbjct: 17565 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 17624
Query: 1368 DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
D T NS T+ W P + I GY + E E ++ + + +T L
Sbjct: 17625 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 17680
Query: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
T EY + + ALN + +G+ ++V + + + A P L S + VR
Sbjct: 17681 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 17734
Query: 1477 -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
RI G +P ++ + T + ++ GV+YT Y +
Sbjct: 17735 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 17793
Query: 1525 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
S + S +++ P + V +V+ +S + W P + V Y +
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 17853
Query: 1581 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
++ +T +E L Y V A+N G P+ V+ A P P
Sbjct: 17854 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 17911
Query: 1636 TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
+ T V+ TS S W P ++ GY V + PK EK + E + + VV
Sbjct: 17912 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 17967
Query: 1690 SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
+GL +Y+ V A + S P GV +T ++ P A E
Sbjct: 17968 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 18027
Query: 1738 ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
ISW E + T V+ + I+ K D YT+T
Sbjct: 18028 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 18086
Query: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
T +N S +V++ P +RF + + +++SW+PP +I+ YI
Sbjct: 18087 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 18136
Query: 1845 IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
++ + +V T IT L+ GTEY + A KS PL
Sbjct: 18137 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPL 18186
Score = 89.4 bits (220), Expect = 4e-17
Identities = 339/1648 (20%), Positives = 590/1648 (35%), Gaps = 249/1648 (15%)
Query: 611 PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
P + TE P+ P +S + W P S I+ Y+L R K S W EA
Sbjct: 22232 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22290
Query: 658 TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
GH ++T++ L YE ++ + G+ E R F++ P T +TG
Sbjct: 22291 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22346
Query: 714 ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
T A S ++ S V+ +++E +E D + T
Sbjct: 22347 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22398
Query: 774 SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
++ + D + G +Y + + + G ++ ++ P P V V S V+
Sbjct: 22399 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22456
Query: 831 WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
W P+ IT Y + S + +N + ++ L ++Y+ + +
Sbjct: 22457 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22516
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
V + ES P++ + P + T P + V+ ++I W P S + GY
Sbjct: 22517 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22570
Query: 938 RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
V+ N + ++P + +VTGL G+ Y F+ +A VS E S+P+
Sbjct: 22571 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22629
Query: 991 AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
AQ +DAP + + T STV + W+ P +++ GY +
Sbjct: 22630 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22687
Query: 1030 ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
TV G ++ V ++K + SE T V + PKA
Sbjct: 22688 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22743
Query: 1080 -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
G T++ GS + + P P+I + G + E + T
Sbjct: 22744 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22795
Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
+ V+ YT+ V + ++ KV+ P L + + T+
Sbjct: 22796 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22854
Query: 1194 SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
+W S + G IT ++ + L V+ S L EY V V
Sbjct: 22855 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22912
Query: 1251 KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
VP+ I A +P PP G + + + W P S +++N+LV
Sbjct: 22913 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22972
Query: 1301 -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
R++ V + V D + +T+L+ G +Y V++V S P
Sbjct: 22973 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 23025
Query: 1354 QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
P+ D T +S ++ W P I GY + + R
Sbjct: 23026 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 23085
Query: 1403 EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
RN+ T+ +L G +Y + A+N G E I + V ++P DLE+
Sbjct: 23086 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 23144
Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
++ I A R+ +G PV ++ G A+ + + Y++
Sbjct: 23145 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23197
Query: 1518 V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
+ Y + S S + + Y T PS ++V +V +S+++ W
Sbjct: 23198 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23256
Query: 1563 -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
+ +PV Y + + KT T +T I GL Y V +N G
Sbjct: 23257 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23315
Query: 1622 QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
+P + V+ +P P L+ VT ++++ W P +LTGY +
Sbjct: 23316 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23375
Query: 1674 PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
MK + L P V+ L +Y E V ++T+T+ Q V+ T++
Sbjct: 23376 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 23435
Query: 1724 VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
+ P++ A E I I+ R F + + + ++ K +
Sbjct: 23436 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 23495
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
T ++ +Y + L + + VI ++ S+ +SW+PP
Sbjct: 23496 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 23555
Query: 1838 -ARITGYIIKY---EKPG-SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
A ++GY+++ +PG P E V R + T L G EY V A N+
Sbjct: 23556 GAPLSGYVVEQRDAHRPGWLPVSESVTR-----STFKFTRLTEGNEYVFRVAA--TNRFG 23608
Query: 1893 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSG 1951
+ + E + +P P PE L + + +T +P D G G Q+ G
Sbjct: 23609 IGSYLQSEVIECRSSIRIPGP----PETLQIFDVSRDGMTLTWYPPEDDG-GSQVTGY-- 23661
Query: 1952 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPH 2011
V ++ + + R P T T R+R + E ++ I P
Sbjct: 23662 ---IVERKEVRADRWVRVNKVPVTMT--RYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 23716
Query: 2012 GP--GLNPNASTGQEALSQTT--------ISWAPFQD-----TSEYIISCHPVGTDEEPL 2056
P ++P A G+ + T ++W+ +D + Y+I V E
Sbjct: 23717 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 23776
Query: 2057 QFRVPGTSTSATLTGLTRGATYNIIVEA 2084
P TLT L +GA Y V A
Sbjct: 23777 CNTTPTKIREYTLTHLPQGAEYRFRVLA 23804
Score = 88.2 bits (217), Expect = 8e-17
Identities = 177/778 (22%), Positives = 292/778 (37%), Gaps = 127/778 (16%)
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
T ++L G EY V V S P + D P +PP DL+ TN+
Sbjct: 9772 TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9831
Query: 1279 -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
G +TW APP D PV + V +L + + V+ +
Sbjct: 9832 VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9885
Query: 1332 TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
T + +V+++ + L + G P G I F ++A+ T+ W P+ +
Sbjct: 9886 TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9943
Query: 1385 ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
IT Y I H S P+E + T+ L G EYV I+A N
Sbjct: 9944 ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9996
Query: 1435 --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
+ P +V P V + T S+ ++W+ P V Y + +T
Sbjct: 9997 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 10056
Query: 1489 -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
P++ T+ S ++GL G DY VYA+ G PAS S P +
Sbjct: 10057 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 10113
Query: 1540 TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
P +VTD +S ++W P S VTGY V + K K T
Sbjct: 10114 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10173
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
++ + GL+ Y V A N +G +P T V ++K V+P L A
Sbjct: 10174 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 10227
Query: 1655 PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10287
Query: 1703 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10347
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10348 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10405
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10406 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10465
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 1916
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10466 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10516
Score = 84.7 bits (208), Expect = 9e-16
Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 6881 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6940
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 6941 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6995
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 6996 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 7055
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 7056 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7115
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 7116 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7171
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 7172 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7226
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 7227 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7286
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 7287 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7344
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
L G Y V + S P T I AV
Sbjct: 7345 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7403
Query: 1272 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
+L T G ++TW I + + V + V + SD G
Sbjct: 7404 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 7454
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
T + +V+ + K G P D +D+T S + W PR + IT
Sbjct: 7455 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7512
Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
Y + R + V H +S T L P EY+ + A N +
Sbjct: 7513 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 7565
Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
SP+ Q P LE T ++ ++W P + Y + + + V
Sbjct: 7566 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7625
Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
+ +P +T + GL Y V A + G G S++PI I + ID P
Sbjct: 7626 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 7683
Query: 1547 QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
+ V DV S+ + W + + Y V K G G T+ + GL
Sbjct: 7684 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 7742
Query: 1603 QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
EY V A N +GES+P L + + P L+ +T + +WT P
Sbjct: 7743 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 7802
Query: 1656 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
+T Y V + G + ++ + V+ L E S+Y + +
Sbjct: 7803 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 7856
Query: 1712 RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
Q T +E+ PP V D T+ + + W I + ++
Sbjct: 7857 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 7916
Query: 1758 AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
G ++ +T PD ++ +T + GT+ + + N+ P + D
Sbjct: 7917 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 7975
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
++ P +L + ++W+PP + I GY ++ G+ V RP
Sbjct: 7976 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 8035
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ G+ P EY + V A+ SEP
Sbjct: 8036 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 8066
Score = 83.6 bits (205), Expect = 2e-15
Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 16045 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16104
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 16105 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16149
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 16150 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16209
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 16210 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16267
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 16268 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16321
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 16322 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16378
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 16379 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16438
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 16439 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16497
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 16498 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16557
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 16558 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16617
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 16618 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16674
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 16675 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16729
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 16730 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16788
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 16789 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16848
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 16849 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16906
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 16907 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16964
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 16965 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 17016
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 17017 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17076
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
+ + L+ EY ++A+N G ES P+V P P F T ++
Sbjct: 17077 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17130
Query: 1645 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
S+ QW P + GY + + K + L +YE
Sbjct: 17131 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17190
Query: 1701 SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
VYA + ++ + PP IT+ W ITG+
Sbjct: 17191 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17250
Query: 1755 QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
V+ P R +K + +T++GL Y+ + N
Sbjct: 17251 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17294
Score = 82.0 bits (201), Expect = 6e-15
Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 21470 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21529
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 21530 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21574
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 21575 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21634
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 21635 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21689
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 21690 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21748
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 21749 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21804
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 21805 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21863
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 21864 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21922
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 21923 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21981
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 21982 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 22040
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 22041 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22100
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 22101 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22159
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 22160 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22218
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 22219 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22278
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 22279 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22335
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 22336 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22391
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 22392 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22443
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 22444 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
+EY V ++N G S+PL + +P APT + V+ ++S +W P
Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22562
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++ GY V + +KE + + V+GL+ +Y+ YAL S+ +
Sbjct: 22563 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22622
Query: 1715 QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
+ + V P R VTD T +T+++ W + G+ ++ P +
Sbjct: 22623 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 22682
Query: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
TI D +T+T L G Y+ + N
Sbjct: 22683 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 22715
Score = 79.3 bits (194), Expect = 4e-14
Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)
Query: 1412 SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
S +T L G EY I+A+N E P++ V D P+ EV T S++
Sbjct: 16390 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 16449
Query: 1466 ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
+ W+ PA + Y + + G + + ++GL DY V A
Sbjct: 16450 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 16509
Query: 1522 TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
G SP S+ + + + P+ +V D+ +S+ + W + GY V
Sbjct: 16510 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 16569
Query: 1575 TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
+ G T G ++T + +E L EY + A N +G + +V+
Sbjct: 16570 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 16629
Query: 1627 TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
+ DL+ ++ + R TP+ K G +++ +
Sbjct: 16630 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 16685
Query: 1683 DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
+SS L +Y+ Y L +++ ++ A V L+ SPP +VT+ T+ ++
Sbjct: 16686 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16745
Query: 1741 TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
+I+W I + V+ A ++ S+ I LQ G Y +
Sbjct: 16746 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16805
Query: 1797 NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
N+ P I + P + T NS+ +SW P ++I YI++ +
Sbjct: 16806 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16865
Query: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
S R + +A IT L G EY V+A+ +S+P
Sbjct: 16866 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 16909
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19763 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19822
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19823 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19874
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19875 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19926
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19927 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19984
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19985 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 20044
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 20045 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20101
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 20102 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20155
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 20156 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20206
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20207 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20266
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20326
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20327 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20385
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20441
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 20442 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20486
Score = 75.5 bits (184), Expect = 6e-13
Identities = 200/944 (21%), Positives = 346/944 (36%), Gaps = 118/944 (12%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 15252 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 15308
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 15309 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15368
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 15369 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15428
Query: 1071 -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
+P T F T +PG PP N V +T +I I W + G+
Sbjct: 15429 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15485
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 15486 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15544
Query: 1169 KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 15545 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15603
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 15604 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15663
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E + + ++ + + + L G Y V +
Sbjct: 15664 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15722
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 15723 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15782
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V T+T L G EY + A N E + +Q +V + +
Sbjct: 15783 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15837
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 15838 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 15895
Query: 1504 --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
++ +K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 15896 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15952
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 15953 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 16009
Query: 1612 VYAQNPSGE-----SQPLVQTAVTTIPAPTDLK-FTQVTPTSLSAQWTPP----NVQLTG 1661
+ A+N G+ S+P V +P P T + S+ QW P ++ G
Sbjct: 16010 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16069
Query: 1662 YRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GV 1717
Y + KE+ + ++N P + +GL +YE V A +P++
Sbjct: 16070 YHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSEC 16127
Query: 1718 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
+ PP R T ++T+ W+ T ITG+ V+
Sbjct: 16128 YVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 16171
Score = 75.1 bits (183), Expect = 7e-13
Identities = 125/581 (21%), Positives = 213/581 (36%), Gaps = 71/581 (12%)
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWD 1469
+ + N T S+ +N E + + + V D P DL+V T TS +SW
Sbjct: 12358 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVR--VLDTPGPVSDLKVSDVTKTSCHVSWA 12415
Query: 1470 AP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
P V +Y + E + T K++ ++ L PG +Y V AV G
Sbjct: 12416 PPENDGGSQVTHYIVEKREADRKT-WSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 12474
Query: 1526 DSPASSKP---ISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
+ P ++ + +E D P +++VT++ NS ++ WLP + + GY +
Sbjct: 12475 PGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 12534
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTTIPA 1634
+ P T+ + + + GL+ +Y V A+N G S P V A +
Sbjct: 12535 EEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLP 12594
Query: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
P L Q+T + G ++R+ P VV S +
Sbjct: 12595 PKILMPEQITIKA-------------GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12641
Query: 1695 ATKYE-VSVYALKD---------TLTSRPAQGV------VTTLENVSPPRRA-RVTDATE 1737
K + S+ +KD +LT+ + G V ++ PP+ ++D
Sbjct: 12642 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12701
Query: 1738 TTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
++SW E IT + V+ + + S + L PG +Y +
Sbjct: 12702 DACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRV 12761
Query: 1794 YTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGY 1843
N S P+ A P N R + + V+W P + I GY
Sbjct: 12762 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 12821
Query: 1844 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 1903
+I+ ++ S TE GL G EY+ + AL S P K T+
Sbjct: 12822 LIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPP---SKPTEY 12878
Query: 1904 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGI 1944
+ + + P PE++DV + + P +D G+ I
Sbjct: 12879 VTARMPVDPPG--KPEVIDVTKSTVSLIW-ARPKHDGGSKI 12916
Score = 72.0 bits (175), Expect = 6e-12
Identities = 284/1399 (20%), Positives = 497/1399 (35%), Gaps = 195/1399 (13%)
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
G + I+ H++ + T + P S TV+ + P V+EI S
Sbjct: 10966 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 11022
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
++W D Y + E D P +ATS L G +Y+ V
Sbjct: 11023 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11081
Query: 794 SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
++ G + + A D PP P D VD T + + W++P +PITGY +
Sbjct: 11082 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11141
Query: 844 VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
Y EG+ + N ++ LQ G Y + A V T + I+ +
Sbjct: 11142 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11199
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
P S + D++ +E VK P + + G V G + +
Sbjct: 11200 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11254
Query: 957 SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
+ F+ V + + T +++ VS+ SK + A T LD P + ++ T
Sbjct: 11255 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11312
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ + W PP+ + + Y + TR+ + G S +K + +LQ EY
Sbjct: 11313 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11372
Query: 1066 LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
+ A P T + S P P T++TE ++WT +P G
Sbjct: 11373 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11432
Query: 1115 FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
+ + R G T + V+GL G Y + + G + +P + +
Sbjct: 11433 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11492
Query: 1171 ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
+ P PP N L+ + + W + + I GY + Q N + +
Sbjct: 11493 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11551
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
Q + L G EY + E P +++++I PP +L T
Sbjct: 11552 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11611
Query: 1280 PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 11612 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11669
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 11670 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11720
Query: 1382 R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
+ IT + + + + G R + NL EY + A N
Sbjct: 11721 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11778
Query: 1434 ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
++P+L P +L + T + + W P ++Y G
Sbjct: 11779 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11838
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
+ + K T + + V+ I + V + + S K + + ++ KP
Sbjct: 11839 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11896
Query: 1546 SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
V D +S V + + + R+ + P P T D T++T
Sbjct: 11897 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11946
Query: 1599 IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
I+ + ++ ++ V A N +G V P P +LK V+
Sbjct: 11947 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 12006
Query: 1647 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
+ W PP G ++ EK K + + S++V+ G V E + Y +
Sbjct: 12007 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 12064
Query: 1707 DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
++ G T + V P VT ++ +T+ W ++ITG
Sbjct: 12065 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 12124
Query: 1754 FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
+ ++ + P+ ++ P+ R + L P +Y+ + N+ + S PV
Sbjct: 12125 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 12183
Query: 1806 VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
V D P+N R + TT +S+ + W P A I GY+++ + P E
Sbjct: 12184 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12243
Query: 1859 PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 1914
R E T+T L+ EY V A NQ +G + EL + + P
Sbjct: 12244 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEI 12295
Query: 1915 LHGPEILDVPSTVQKTPFV 1933
L PEI D+ ++++K V
Sbjct: 12296 LEPPEI-DLDASMRKLVIV 12313
Score = 68.2 bits (165), Expect = 9e-11
Identities = 218/1049 (20%), Positives = 384/1049 (36%), Gaps = 174/1049 (16%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 6787 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6846
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 6847 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6904
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 6905 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6963
Query: 1251 KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
P + T V PP +L ++ ++++ W PP S L +
Sbjct: 6964 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 7023
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
R K+ + + P + +T L G +Y+ VS+ + S P D
Sbjct: 7024 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7082
Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
D++A + I P +P + D+V + + + + L+
Sbjct: 7083 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 7142
Query: 1420 PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
E V+S + + L L + T+S P++L+ T S+ ++
Sbjct: 7143 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 7202
Query: 1468 WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
W+ P + G SP+ + V + + T+ L G
Sbjct: 7203 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 7250
Query: 1513 DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
+Y V A G G+ +P++++ + D P ++ D NSI + W P
Sbjct: 7251 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 7310
Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + GY V P+ G K G +T+M + GL+ Y V A N G S+P
Sbjct: 7311 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7367
Query: 1624 LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
T AV T AP L T L A T P ++T + + K
Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7427
Query: 1670 EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
+ K I + P S+V + + + + + Y ++ A VV L+
Sbjct: 7428 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 7480
Query: 1726 PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
PP +TD T + ++W + IT + V+ + + + T+K ++
Sbjct: 7481 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 7538
Query: 1780 ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
T L P +Y +Y + + ++SP I A D P+ L T +++ +
Sbjct: 7539 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 7596
Query: 1832 SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
+W P + ITGY ++ P + + T + GL +Y V+A
Sbjct: 7597 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 7656
Query: 1887 -----KNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTG 1941
K ++ +EP++ + D P P P + DV T + + T P +D G
Sbjct: 7657 LAGPGKPSKSTEPILIKDPIDP-------PWPP-GKPTVKDVGKTSVRLNW-TKPEHDGG 7707
Query: 1942 NGIQ--------------------LPGTSGQQPSV--GQQMIFEEHGFRR---TTPPTTA 1976
I+ +P T P + GQ+ F + + P +
Sbjct: 7708 AKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPS 7767
Query: 1977 TPIRHRPRPYPPNVGEEIQIGHIPREDVD 2005
P+ R + YPP+ +++ +I + D
Sbjct: 7768 DPVLCREKLYPPSPPRWLEVINITKNTAD 7796
Score = 62.8 bits (151), Expect = 4e-09
Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 20222 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20276
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 20277 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20336
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 20337 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20394
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 20395 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20451
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 20452 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20509
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 20510 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20569
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 20570 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20625
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 20626 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20685
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 20686 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20745
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 20746 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20801
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 20802 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20859
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 20860 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20918
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 20919 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20977
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 20978 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 21037
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 21038 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21154
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 21155 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21211
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
T E+ + L+ V+A+N G S P+ TI P +K +TP LS
Sbjct: 21212 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 21261
Query: 1653 TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
P Q+T G+ V + K P I+ D + S + +K E + ++K+
Sbjct: 21262 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21321
Query: 1709 LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
+ V T+ + PP + R + ++ +SW +
Sbjct: 21322 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21381
Query: 1751 --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
IT + ++ QT + R ++ + L +Y+ + N S P+V
Sbjct: 21382 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21440
Query: 1808 DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
A P T + + ++W P + +TG+ ++ ++ S +
Sbjct: 21441 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 21500
Query: 1858 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V E TGL G +Y V A + S P
Sbjct: 21501 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21537
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 9187 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9244
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9245 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9297
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9298 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9351
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9352 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9411
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9412 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9471
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9472 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9503
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24421 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24475
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24476 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24535
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24536 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24595
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24596 CENLGGESEWSEISEPI--TPKSD 24617
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24804 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24861
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24862 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24921
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24922 EVDETREVSMT 24932
Score = 35.8 bits (81), Expect = 0.50
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)
Query: 1534 ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
+ + + + DKP+ V + + NS + W P + S +T Y V +
Sbjct: 24410 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24469
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
++ T I L Y V AQN G S PL ++V I +P + T
Sbjct: 24470 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24529
Query: 1642 QVTPTSLSAQWTPP 1655
VT S W PP
Sbjct: 24530 AVTKDSCVVAWKPP 24543
Score = 31.6 bits (70), Expect = 9.4
Identities = 38/169 (22%), Positives = 66/169 (39%), Gaps = 21/169 (12%)
Query: 2027 SQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081
S ++SW+ +D + Y I TD+ + T+T T+TGL A Y
Sbjct: 24039 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 24098
Query: 2082 VEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESG 2138
+ A D + E VV + ++P+ + ++S +V +WE+ G
Sbjct: 24099 IIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDG 24153
Query: 2139 FKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2187
K + LG+ + + S W N K D+Q G ++ T
Sbjct: 24154 GK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24194
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 148 bits (373), Expect = 7e-35
Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 22848 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22906
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 22907 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22956
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 22957 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23013
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 23014 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23073
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 23074 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23133
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 23134 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23185
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 23186 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23244
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 23245 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23302
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 23303 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23361
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 23362 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23421
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 23422 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23481
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 23482 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23539
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 23540 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23599
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 23600 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23659
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 23660 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23719
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 23720 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23771
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 23772 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23830
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 23831 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23889
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 23890 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23946
Query: 1629 VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
T P + + VT +S+S W+ P ++TGY + ++
Sbjct: 23947 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24006
Query: 1677 EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
++ V+GL+ +Y+ + A D + TS ++ VV + S P
Sbjct: 24007 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24066
Query: 1732 VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
+ ++ ++T+ W + I G+ V+ +G + +++ K + + +TI GL
Sbjct: 24067 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 24125
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
T+Y+ ++ N+ S P
Sbjct: 24126 ATEYEFRVFAENETGLSRP 24144
Score = 140 bits (353), Expect = 1e-32
Identities = 320/1467 (21%), Positives = 549/1467 (37%), Gaps = 222/1467 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13418 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13474
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13475 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13519
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13520 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13576
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13577 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13636
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13637 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13694 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13746
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13747 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13805
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13921
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13922 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13981
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 13982 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14040
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 14041 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14093
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 14094 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14143
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 14144 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14203
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 14204 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14263
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 14264 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14323
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 14324 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14383
Query: 1526 -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 14384 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14443
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
+ + + I T ++V+++ +NP+G+ V V P P +
Sbjct: 14444 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14501
Query: 1638 LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
L+ T +T S++ W P + ++T Y V +++ K + A + V+
Sbjct: 14502 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 14557
Query: 1691 GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
GL +Y V A + P + V E SPP + D T++T++++W
Sbjct: 14558 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 14617
Query: 1745 RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
ITG+ ++A + Q T+K + L G +Y + +N RS+
Sbjct: 14618 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 14675
Query: 1804 -----PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 1858
PV++ T + +LR + +Q G IK E P V+
Sbjct: 14676 PRESRPVIVKEQTML-PELDLRGI----------YQKLVIAKAGDNIKVEIP------VL 14718
Query: 1859 PRPRPGVT---------EATITGLEPGTEYTIYVI--ALKNNQKSEPLIGRKKTDELPQL 1907
RP+P VT + E TI I ++++ PL R E+ +
Sbjct: 14719 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 14778
Query: 1908 VTLPHPNLHGPEILDVPSTVQKTPFVT 1934
+T+ ++ GP + + FVT
Sbjct: 14779 ITIQVHDIPGPPTGPIKFDEVSSDFVT 14805
Score = 129 bits (323), Expect = 4e-29
Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7404 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7462
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7509
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7510 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7569
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7570 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7629
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7687
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7688 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7747
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7748 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7806
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7807 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7866
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7867 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7926
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7927 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7985
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 7986 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8039
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 8040 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8098
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 8099 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8158
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8218
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 8219 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8276
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 8277 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8336
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 8337 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8396
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 8397 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8456
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 8457 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8516
Query: 1624 LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
V + AP VT S+ +W P + GY + T
Sbjct: 8517 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8576
Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
+ ++ V GL+ Y V A + P T + +SPP
Sbjct: 8577 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 8636
Query: 1731 RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
RVTD + TTI + W I G+ VD + T K VR YT+ ++
Sbjct: 8637 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 8696
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
G DYK+ + +N P
Sbjct: 8697 GADYKLRVSAVNAAGEGPP 8715
Score = 128 bits (321), Expect = 7e-29
Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 7064 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7119
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 7120 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7179
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 7180 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7239
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 7240 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7298
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7353
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 7354 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7406
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 7407 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7463
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 7464 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7522
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 7523 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7581
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
V K K + P I D I P PP PT ++G ++R+ W P
Sbjct: 7582 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 7638
Query: 1292 -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
+ ++++ +E V P+ +L L+ G EY V +V + E
Sbjct: 7639 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 7697
Query: 1347 --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
S P+ R+K S P ++ +IT N+ + W P + IT Y + G
Sbjct: 7698 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7757
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
D T+T LT G+ YV + A N E +L T P
Sbjct: 7758 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7816
Query: 1453 DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
L VV T + + W+ P ++ Y I E G V+ G ++ +
Sbjct: 7817 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7876
Query: 1509 KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
G + V A G G ++ +SI T P + VTD I++ W P
Sbjct: 7877 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 7936
Query: 1565 ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
SP+ GY V P + + + + EG+ P EYV+ V A N G
Sbjct: 7937 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 7996
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
S+P + + + D K T T + + G ++ + + P+ ++
Sbjct: 7997 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 8048
Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
D V S + +S + L+ + R G+ T TLEN
Sbjct: 8049 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8107
Query: 1724 VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
P + + +D T+++ ++W I + ++ A +T I + S+T
Sbjct: 8108 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8167
Query: 1780 ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
+ L P +Y + +N ++ + D D P ++ T ++ ++
Sbjct: 8168 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8227
Query: 1833 WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
W+PP ++I GYII+ G + + T GLE G EY V A
Sbjct: 8228 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8287
Query: 1889 NQKSEP 1894
SEP
Sbjct: 8288 AGISEP 8293
Score = 127 bits (318), Expect = 2e-28
Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 11933 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11991
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 11992 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12051
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 12052 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12109
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 12110 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12169
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 12170 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12228
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 12229 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12287
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 12288 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12345
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 12346 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12402
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 12403 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12461
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 12462 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12520
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 12521 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12574
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 12575 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12634
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 12635 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12693
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 12694 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12743
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 12744 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12801
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 12802 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12861
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
+ TA Q E T GL+ +Y + + + +TAV P P+D
Sbjct: 12862 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 12910
Query: 1638 LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
P ++ A+ PP + L+ + +T K T PM ++ D +
Sbjct: 12911 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 12963
Query: 1687 V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
+ G+ +A + + L KD T+T+ + G + L+ PP
Sbjct: 12964 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13023
Query: 1731 RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
++ +SW E IT + VD + Q + + S ++ L G
Sbjct: 13024 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 13083
Query: 1787 TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
+Y+ + N PV + A D P T + + VSW+PP
Sbjct: 13084 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 13143
Query: 1838 -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
+ ITGY++ EK + R + E T+ TGL+ GTEY V A+ +P
Sbjct: 13144 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 13201
Score = 125 bits (314), Expect = 5e-28
Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
N+ + W P S I+ Y + R K S+ RW A P + GL+ G YE
Sbjct: 14214 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14272
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ + + G + S++V + + P ++ VT+ T S ++
Sbjct: 14273 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14320
Query: 740 W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W ++G+ VE++ + GDE D TA + +PDL KY +
Sbjct: 14321 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14378
Query: 793 ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
I++ G + ++ + + PD +D ++VVR R PI G +P
Sbjct: 14379 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14435
Query: 849 VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
V + +NL AN ++ + + I ++ V+ E +S V
Sbjct: 14436 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14489
Query: 908 ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
P P +L+ ++T VT+ W P S +T Y V+
Sbjct: 14490 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14549
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
+ T+ +VTGLS G Y+F+V A + +P + K P +L ++ T ST
Sbjct: 14550 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14608
Query: 1013 VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
V + W P+ ++ITGY + R+G + ++ + +RNL EYT ++
Sbjct: 14609 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14666
Query: 1068 AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
A+ S ++ + +P + +VI P P +
Sbjct: 14667 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14726
Query: 1115 FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+K G + Q E T+ S + ++ Y + E I +V
Sbjct: 14727 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14786
Query: 1174 LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PPT + +T SW E I+ Y + T+ L V
Sbjct: 14787 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14846
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
T L+ GLEY V I+ I A VP PP + T + D+M
Sbjct: 14847 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14904
Query: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
++W P S + L + K + ++S + N + L G Y V +
Sbjct: 14905 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 14964
Query: 1342 YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
+S P + + +D P +IT ++ T+ W P T IT Y +
Sbjct: 14965 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15024
Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
+ + N T++ LT Y ++A N I S SD
Sbjct: 15025 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 15080
Query: 1454 LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
+ V A + + + + +R+ +G P E++ G + T
Sbjct: 15081 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15140
Query: 1512 VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
D++ + A T +P N + +D+P + VT+V
Sbjct: 15141 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 15199
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
+ W P + + Y V + T + T++ + L EY+ V
Sbjct: 15200 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 15258
Query: 1614 AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
A N G +PL V + P + + T +T S+ W P+ ++ Y
Sbjct: 15259 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 15318
Query: 1664 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
V K +K VSGL +YE + A S P+
Sbjct: 15319 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15378
Query: 1719 TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 15379 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 15435
Query: 1774 DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
SYTITGL +YKI +Y +N P ++
Sbjct: 15436 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15473
Score = 123 bits (308), Expect = 2e-27
Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13112
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 13113 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13172
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13173 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13232
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13233 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13292
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13293 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13351
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13412 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13469
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13470 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13526
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13527 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13581
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 13582 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13638
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 13639 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13689
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 13690 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13746
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 13747 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13806
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 13807 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13866
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 13867 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13926
Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 13927 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13986
Query: 1623 PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
++ T I APT + L+ + + L + P K+ K
Sbjct: 13987 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 14044
Query: 1677 ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
+I P SS + + AT+ + Y + T ++ VT L+
Sbjct: 14045 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 14101
Query: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
PP +++ + T++W E + +T + + D++S +
Sbjct: 14102 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 14161
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
T L G +Y + +N + PV + +D P T N+ VSW+
Sbjct: 14162 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 14221
Query: 1835 PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
P + ITGY ++ + S + +TGL+ G+ Y V A
Sbjct: 14222 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 14276
Score = 122 bits (307), Expect = 3e-27
Identities = 286/1294 (22%), Positives = 482/1294 (37%), Gaps = 173/1294 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20777
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20778 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20833
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20834 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20890
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20891 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20941
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 20942 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21000
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 21001 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21060
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 21061 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21116
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 21117 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21176
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 21177 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21233
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 21234 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21289
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 21290 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21348
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 21349 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21408
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 21409 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21468
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 21469 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21528
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
+ + + T+ GL P Y + A+N P +S ++ T +P +
Sbjct: 21529 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 21587
Query: 1638 ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
+K + Q P ++T ++ V +++ EI S+S+
Sbjct: 21588 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 21644
Query: 1688 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
V AT+ VY ++ S A+ + +P + R T+ T +T+ W
Sbjct: 21645 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21701
Query: 1745 RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
IT + ++ + K + +SYT L G +Y+ + +N
Sbjct: 21702 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 21761
Query: 1799 ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
S PVV T DAP T NS+ ++W P + I YI+ + EK
Sbjct: 21762 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 21821
Query: 1850 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT 1909
+ +V+ + T +TGL G EY +V+A +N P G + + + V
Sbjct: 21822 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVN 21880
Query: 1910 LPHPNLHGPEILDVPSTVQKTPFV--THPGYDTG 1941
P P P ++ V T + T + + P +D G
Sbjct: 21881 PPGP----PTVVKVTDTSKTTVSLEWSKPVFDGG 21910
Score = 116 bits (291), Expect = 2e-25
Identities = 282/1346 (20%), Positives = 481/1346 (35%), Gaps = 213/1346 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17781
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17782 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17828
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17829 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17884
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17885 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17944
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 17945 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18003
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18056
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 18057 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18115
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18233
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 18234 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18287
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 18288 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18347
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 18407 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18465
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 18466 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525
Query: 1360 ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18645
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 18646 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18693
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 18694 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18749
Query: 1566 SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 18750 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18806
Query: 1613 YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
+N SG V V P AP +L +V S++ W PP ++T Y +
Sbjct: 18807 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 18863
Query: 1668 PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
K +T + + + + L Y V A + PA+ V E
Sbjct: 18864 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 18923
Query: 1724 VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
PP R + D T T TI W K E+ ITG+ V+ + G +
Sbjct: 18924 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 18981
Query: 1779 TITGLQPGTDYKIYLYTLNDNARSSP 1804
TI+GL G +Y + +N+ RS P
Sbjct: 18982 TISGLTAGEEYVFRVAAVNEKGRSDP 19007
Score = 116 bits (291), Expect = 2e-25
Identities = 149/690 (21%), Positives = 263/690 (38%), Gaps = 70/690 (10%)
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
PP ++ I ++ ++W PP L+ ++V + +S S + +
Sbjct: 23462 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 23520
Query: 1325 LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
T L G EYV V++ Y Q E R + P + D++ + T+
Sbjct: 23521 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 23579
Query: 1378 WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
W P + +TGY + R ++VP + T LT G EY + A+N
Sbjct: 23580 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23639
Query: 1434 R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
R P++ P++ V T TS+ ++W P V Y I
Sbjct: 23640 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 23699
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ + + T P T++ L G +Y V A G + P ++ +
Sbjct: 23700 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23759
Query: 1543 DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
+ P ++ + I V+ + + P+ G + + K G +K +T
Sbjct: 23760 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 23818
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
E+ I+ + +N G+ ++ V P + L++ + S+ W
Sbjct: 23819 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23878
Query: 1654 PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 23879 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 23935
Query: 1708 TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
S+P ++ VT ++PP V D T++++++SW R K + +TG+ ++
Sbjct: 23936 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 23995
Query: 1758 AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
+ ++ K + + YT+TGL P +Y+ + ND + S PVV D
Sbjct: 23996 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24054
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 24055 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 24114
Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ TI GL TEY V A S P
Sbjct: 24115 DKQFTIGGLLEATEYEFRVFAENETGLSRP 24144
Score = 113 bits (283), Expect = 2e-24
Identities = 299/1397 (21%), Positives = 486/1397 (34%), Gaps = 195/1397 (13%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 18400 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18454
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 18455 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18512
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 18513 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18571
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 18572 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 18625
Query: 905 DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 18626 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18685
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
L G+ VT L Y F++ A++ +P T AQ+ +
Sbjct: 18686 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18734
Query: 997 --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 18735 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 18791
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 18792 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18851
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 18852 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18967
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
++ ++ +V + T L+ G EY V V + S P + +I + P
Sbjct: 18968 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 19024
Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
+L F P V + V + + V LSI
Sbjct: 19025 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 19084
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
+ V GT + +S + + G P ID +++ +S T+ W
Sbjct: 19085 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 19136
Query: 1379 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
P I+ Y I E S +R SI + LT G+EY + A N
Sbjct: 19137 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19195
Query: 1434 -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
E S ++ + P +VV AT +++L++W P V Y + Y E
Sbjct: 19196 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19255
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
+ + + + +SGL G+ Y VYA + G G S +P+ R
Sbjct: 19256 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 19313
Query: 1543 DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
D P Q +VT++ S+S+KW + +TGY V K +T
Sbjct: 19314 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19373
Query: 1599 IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
+ L Y V+A+N PS + P +V+ V D+KF V +
Sbjct: 19374 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 19432
Query: 1651 QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
+ N + G + V K G E ++ D+ +++ + V L
Sbjct: 19433 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19492
Query: 1706 KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
K+ +R L+ PP + T ++SW E G +D V
Sbjct: 19493 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 19551
Query: 1763 GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
+ + TI + + S +T L G +Y + +N P+ +D T
Sbjct: 19552 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19611
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
P++L + T S+ + W P + I+GYII+ + S V +
Sbjct: 19612 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19671
Query: 1870 ITGLEPGTEYTIYVIA-----LKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 1924
TGL G EY V A L ++ PLI + V LP P P+I+D
Sbjct: 19672 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP------VFLPSPP-SKPKIVDSG 19724
Query: 1925 STVQKTPFVTHPGYDTG 1941
T +V P +D G
Sbjct: 19725 KTTITIAWV-KPLFDGG 19740
Score = 112 bits (281), Expect = 3e-24
Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 14101 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14155
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 14156 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14202
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 14203 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14262
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 14263 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14322
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 14323 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14381
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 14382 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14441
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 14442 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14498
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 14499 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14557
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 14558 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14616
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 14617 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14675
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 14676 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14732
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 14733 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14792
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 14793 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14851
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 14852 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14911
Query: 1383 AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 14912 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14971
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 14972 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15028
Query: 1492 QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ + T+SGL Y V A G SP S +I R +++ P
Sbjct: 15029 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15088
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 15089 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15141
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
+ ++ A NP G ++ + V P P + L T+VT
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15201
Query: 1650 AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
W PP ++ Y V+ K +T + N+A + + + V+ L+ +Y
Sbjct: 15202 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 15258
Query: 1699 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
V+ Y + + L S P V PP+ VT T+ ++ + W ++
Sbjct: 15259 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15317
Query: 1759 VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
+ QR IK + ++ Y ++GL G +Y+ + N S+P
Sbjct: 15318 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 15377
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
D P N R L T+ +S+ ++W P + ITGY+++ P ++V P
Sbjct: 15378 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 15437
Query: 1863 P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
T TITGL EY I + A+ + EP +
Sbjct: 15438 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15472
Score = 110 bits (275), Expect = 2e-23
Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
N V P P+ S E+T V+SW D G ++ + E+ + + + +
Sbjct: 10535 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 10588
Query: 769 PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
P T+ T+ + LL G+ YI N+Y IS+ + + + PDAP P V
Sbjct: 10589 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 10648
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
+V S +V W++P PIT Y + ++ + + DL G
Sbjct: 10649 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 10708
Query: 875 QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
QY + A E P + P + + ++ T V + W PP
Sbjct: 10709 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 10768
Query: 932 -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
S + GY V+ V + P S T +VTGL G TY F+V AV+ ES P
Sbjct: 10769 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 10828
Query: 989 LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
+ +L+ P + N + R A I G ++T R P
Sbjct: 10829 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 10888
Query: 1040 RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
+ +V P SK +RN SL + V +PG PP + E
Sbjct: 10889 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 10945
Query: 1098 VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
V+E + +TW G + + R + +P TS S L G
Sbjct: 10946 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 11005
Query: 1148 EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
+Y++ +V + Q P V K + PL PP +LH + D +++ W +
Sbjct: 11006 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 11062
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
R ITGY + Q + V + + C L G Y V ++
Sbjct: 11063 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 11117
Query: 1257 VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
+ + DT IP VPP +L I T+R + P P+ T
Sbjct: 11118 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 11174
Query: 1301 RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
S +K +E + + S + L T EY ++VS+ + T LD
Sbjct: 11175 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 11230
Query: 1360 ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
PTG I+ D+T T+ W P+ I + E R V S +S T
Sbjct: 11231 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11290
Query: 1415 --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+ +L G EYV + A N + +P + + + P V T + +
Sbjct: 11291 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11350
Query: 1467 SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
SW P + YY TG V + + K T GL G Y V+A
Sbjct: 11351 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 11408
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S S I I P ++ D + + W SP+ GY V
Sbjct: 11409 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 11468
Query: 1575 TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
PG + D Q + GL EY + A N GE +P L ++
Sbjct: 11469 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 11525
Query: 1629 VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
+ I P +++ VT + +++ RV+ P+ K G + K +
Sbjct: 11526 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 11583
Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
+L D V + + A + + Y + +S AQG +V L+ P + +VT+ T
Sbjct: 11584 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11642
Query: 1737 ETTITISWRTKTET----ITGFQVD 1757
+ TISW + IT F V+
Sbjct: 11643 KENCTISWENPLDNGGSEITNFIVE 11667
Score = 110 bits (274), Expect = 2e-23
Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
+T++T S +++W D Y + D + L ST N L+P +
Sbjct: 7420 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 7479
Query: 785 KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
+YI N+Y + E + S I + Q P P + ++ + W P
Sbjct: 7480 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7539
Query: 836 APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
+PITGY + P + +P + + L +Y + A + +S
Sbjct: 7540 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7599
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
T ++ ++ P P+ +D V V + WT PE + + Y ++++
Sbjct: 7600 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7654
Query: 946 LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
+ +P +++ + GL G Y F+V AV+ ES+P L ++
Sbjct: 7655 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7711
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
P L+ +N T +T ++WT P + IT Y + RR + + +K
Sbjct: 7712 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7771
Query: 1053 LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
+ L S Y + A ++S A FTT PG PPY V + T
Sbjct: 7772 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 7826
Query: 1103 -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
+ + W P G + LG R + G+ + V+ + G E
Sbjct: 7827 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 7882
Query: 1150 VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
+ ++ + + + + +P SPP +LH+ D G + ++W E++
Sbjct: 7883 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 7939
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I GY + P ++ + D + + P EY + V V S P
Sbjct: 7940 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7999
Query: 1259 --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
IS+ ++ P P DL +I P R P S V+ S
Sbjct: 8000 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 8059
Query: 1305 ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
+KN+ A L + S A + L N L ++V +
Sbjct: 8060 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 8105
Query: 1356 TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
GL P I SDIT +S + W P G I H+ R +P ++
Sbjct: 8106 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 8163
Query: 1411 NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S T+ +L P EY + A+N G E ++P++ D P D+EV T +
Sbjct: 8164 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 8223
Query: 1464 LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
+ I+W P + Y +I GE E VP T T GL+ G +Y
Sbjct: 8224 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 8280
Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
V A G S S ID P + T ++ D SIS +
Sbjct: 8281 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 8340
Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
W+ + + + K P + G Q E
Sbjct: 8341 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8396
Query: 1600 -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
+ L+P + + +N G ++ P + + T P + F + TS+ +W PP
Sbjct: 8397 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 8455
Query: 1656 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
++ Y + K K PDS +VV+ + KY V+ Y +
Sbjct: 8456 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 8505
Query: 1708 TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
+R G V L P P + V D T ++ + W + I G+
Sbjct: 8506 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 8565
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
++ N + + +++ +++ + GL G Y + N + SP D T
Sbjct: 8566 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 8623
Query: 1812 AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
A D P R T+ ++ + W+PP I GY + + G+
Sbjct: 8624 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8683
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V + T+ + G +Y + V A+ + P
Sbjct: 8684 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 8715
Score = 110 bits (274), Expect = 2e-23
Identities = 298/1381 (21%), Positives = 508/1381 (36%), Gaps = 185/1381 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15191 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15308
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15309 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15367
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15424
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15425 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15484
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15485 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15535
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15536 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15595
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15596 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15652
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15653 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15710
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15711 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15767
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 15768 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15821
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 15822 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15879
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 15880 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15938
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 15939 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15997
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 15998 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16057
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 16058 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16117
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
T + GL Y V A+N +G S+P T T D S
Sbjct: 16118 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 16172
Query: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
+ ++ V G +V P+ I +++ + + AT V
Sbjct: 16173 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 16232
Query: 1702 ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
+ K+ R V L+ PP ++ T T++W+ +
Sbjct: 16233 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 16292
Query: 1751 ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
++ + +T + + +V+ S +T L G +Y + Y + +
Sbjct: 16293 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 16352
Query: 1802 SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
S PVV + DAP T +S++V W+ P + I GY++ K +K G
Sbjct: 16353 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 16412
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 1915
R G +TGL +Y V A SEP + PN
Sbjct: 16413 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN- 16470
Query: 1916 HGPEILDVPSTVQKTPFV--THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPP 1973
P+++D+ + + F+ + P YD G IQ SVG+ + TPP
Sbjct: 16471 -NPKVIDI---TRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE--------WTMCTPP 16518
Query: 1974 T 1974
T
Sbjct: 16519 T 16519
Score = 109 bits (273), Expect = 3e-23
Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6673 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6732
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6733 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6791
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6792 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6851
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6852 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6911
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6912 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6969
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 6970 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7028
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 7029 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7088
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 7089 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7143
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 7144 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7261
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 7262 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7315
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 7316 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7372
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 7373 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7432
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 7433 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7485
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 7486 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7545
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
V + + T ++GL +Y V A+N +G +P T I
Sbjct: 7546 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7605
Query: 1633 PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
P D + P TS+ WT P ++ Y + + KTG + + +A
Sbjct: 7606 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 7662
Query: 1682 P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
++ ++ GLM +Y V A+ S P++ V E + SPPR V +
Sbjct: 7663 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7722
Query: 1735 ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
T+ T + W + IT + V+ V G + T+K T+T L G+
Sbjct: 7723 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 7780
Query: 1789 YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
Y + N +S S + D T P L + T + + W+PP+
Sbjct: 7781 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 7836
Score = 109 bits (273), Expect = 3e-23
Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)
Query: 692 VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
VTRFD S +T +G T F SP + ++ E+ S +SW
Sbjct: 18796 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18851
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ ++ + VE E Y + + T T+ I +L G Y V +E G
Sbjct: 18852 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908
Query: 799 QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
L T++ PP P T+ V + ++W +P++ ITGY V +
Sbjct: 18909 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 18965
Query: 851 GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
GS + T+S L G +Y + AV E S P VI ++ P
Sbjct: 18966 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 19023
Query: 905 DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
+V P V+ + +K+ + + A +R D GQ L ++ +
Sbjct: 19024 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 19072
Query: 960 TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
+ VT LS V Y + S G + P+T + P ++ + ++
Sbjct: 19073 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19132
Query: 1014 LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
+ W PP QI+ Y V + V +V++ ++ L SEY +
Sbjct: 19133 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19190
Query: 1068 AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
A ES + PG P T++T+++TW IG+
Sbjct: 19191 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19250
Query: 1117 LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
L + +A + + +D+ + VSGL G+ Y VY + G+ +
Sbjct: 19251 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19309
Query: 1171 VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
P PP TN+ ++ + D G + ER PD G + TN
Sbjct: 19310 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 19367
Query: 1216 QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
Q+ + DQ + D++S E + VKDD E V D
Sbjct: 19368 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 19426
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
I+ + G ++WA I++ E+ A I +DN
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 19472
Query: 1323 VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
+LT +YV+++ +V + + K G P G ++ + +TA ++
Sbjct: 19473 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 19530
Query: 1377 HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
W P+ A I Y + + H + E + S +T L G EY+ + +
Sbjct: 19531 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 19588
Query: 1432 NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
N E + TV P LE+ + T S+ + W P + Y I
Sbjct: 19589 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19648
Query: 1482 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
E V+ P +GL+ G +Y VYA G S P+ + P+ I
Sbjct: 19649 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 19707
Query: 1541 EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
+ PS+ ++ D +I++ W+ +P+TGY V K+ KT
Sbjct: 19708 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 19766
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
TE TI GL EYV V + N PS S P + P ++++ T +
Sbjct: 19767 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 19826
Query: 1645 PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
S T P +R R P +T + + S ++ + +
Sbjct: 19827 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 19880
Query: 1696 TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
KY +++ ++ L++ VV L+ PP V D T+ + +SW +
Sbjct: 19881 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 19937
Query: 1752 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
+ ++ A+ + + T + SY +T LQ G Y + N+ P
Sbjct: 19938 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 19997
Query: 1812 AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
I P L + + +S+ ++W P +RI Y+++ + G + V
Sbjct: 19998 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 20055
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
T ++GL +EY V A S+P
Sbjct: 20056 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20086
Score = 105 bits (262), Expect = 5e-22
Identities = 346/1650 (20%), Positives = 609/1650 (36%), Gaps = 262/1650 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8843 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8900
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8901 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8947
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 8948 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9007
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 9008 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9063
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 9064 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 9124 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9180
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9181 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9240
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9241 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9296
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 9297 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9356
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 9357 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9412
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9413 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9472
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 9473 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9531
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 9532 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9590
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 9591 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9650
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 9651 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9710
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 9711 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9770
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 9771 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9830
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 9831 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9887
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
N KT ++ P + TI L EYV + AQN G +PL T +
Sbjct: 9888 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943
Query: 1632 IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
+P AP + VT S++ W P +TGY + + K+ T K +N P +
Sbjct: 9944 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 10001
Query: 1686 -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
S V+GL+ + Y+ VYA+ +L S PA T + ++PP +V
Sbjct: 10002 MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 10057
Query: 1733 TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
TD T+++ + W + +TG+ V+ G+ ++ +VR +TGL+ G
Sbjct: 10058 TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 10116
Query: 1787 TDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1842
YK + +N P VI+ + +P +L+ A+ + ++V RI
Sbjct: 10117 AFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGVIRIIA 10174
Query: 1843 YIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE----PLI 1896
Y+ G PP V R EATI T + +KN Q+S L+
Sbjct: 10175 YV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQGVYSLL 10224
Query: 1897 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----PGTSGQ 1952
+ + E + + + ++LDVP V TPF+ H T +L P G
Sbjct: 10225 AKNEAGERKKTIIV--------DVLDVPGPV-GTPFLAH--NLTNESCKLTWFSPEDDGG 10273
Query: 1953 QPSVGQQMIFEEHGFRRTTPPTTATPIRH--------RPRPYPPNVGEEIQIGHIPREDV 2004
P + +I + RR P T T R + + Y + E IG P +
Sbjct: 10274 SP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 10332
Query: 2005 DYHLYPHGPGLNPNASTGQEALSQT----TISWAP--FQDTSE---YIISCHPVGTDEEP 2055
L P P E T T++W P + SE Y++ +GT++
Sbjct: 10333 SEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH 10392
Query: 2056 LQFRVPGTSTSATLTGLTRGATYNIIVEAL 2085
S T+ GL G TY V A+
Sbjct: 10393 KVTNDNLLSRKYTVKGLKEGDTYEYRVSAV 10422
Score = 105 bits (261), Expect = 7e-22
Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 9857 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9916
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 9917 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9976
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 9977 TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10034
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 10035 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10094
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 10095 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10154
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 10155 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10208
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 10209 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10268
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 10269 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10328
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 10329 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10387
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 10388 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10444
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
PPT +R T R + P P + S K+E DV E +
Sbjct: 10445 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10495
Query: 1315 SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
+P+ A+ G VV +S + + + G P G + F ++T
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 10553
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
+ + W P G +I ++ ++ +P ++ + ++ L G +Y+
Sbjct: 10554 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 10612
Query: 1427 SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
I A N S L+ V D P V T S L++W+ P
Sbjct: 10613 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 10672
Query: 1472 -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
++ R+ R+T P +F VP L G Y V A
Sbjct: 10673 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 10720
Query: 1523 GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
G GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 10721 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 10777
Query: 1576 TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
K G + P+ +T+ + GL+ Y V A N +GES P +
Sbjct: 10778 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 10831
Query: 1633 PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
P P +K P L A G +R++ P K KE AP +
Sbjct: 10832 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10891
Query: 1686 SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
+ V+ V +K E+ +Y+L ++ S+ V L+ PPR V++
Sbjct: 10892 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 10949
Query: 1736 TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
+ + ++W+ + IT + V+ V + +P+ T K +S+ L G Y
Sbjct: 10950 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 11007
Query: 1790 KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
+ N R V +D P +L + + + W P +
Sbjct: 11008 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 11067
Query: 1839 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
ITGY+++Y++ G+ ++ + E +TGL+ G Y V K+E ++G
Sbjct: 11068 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 11117
Score = 102 bits (255), Expect = 3e-21
Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10263 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10321
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10322 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10369
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10370 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10429
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10430 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10490 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10547
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10548 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10603
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10604 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10663
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10664 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10723
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 10724 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10781
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 10782 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10841
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 10842 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10900
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 10901 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10946
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 10947 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11005
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 11006 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11064
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 11065 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11122
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 11123 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11174
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 11175 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11226
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 11227 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11283
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
+G +T++ I LQ EYV V A+N G PL T + P+P T +
Sbjct: 11284 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11343
Query: 1644 TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
T + + WT P +TGY + +E TG +N P + V+GL Y
Sbjct: 11344 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 11401
Query: 1699 EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
E V+A S+P+ ++ PP ++ D + T + W TK
Sbjct: 11402 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 11460
Query: 1749 ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
I G+ V+ G R K ++ ++ + GL G +Y+ + N P
Sbjct: 11461 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11518
Score = 102 bits (255), Expect = 3e-21
Identities = 255/1289 (19%), Positives = 459/1289 (35%), Gaps = 229/1289 (17%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17546 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17603
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17663
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17664 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17714
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17715 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17774
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17775 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17833
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 17834 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17889
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 17890 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 17948
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 17949 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 17974
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 17975 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 18020
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 18021 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 18043
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 18044 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 18099
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 18100 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 18159
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 18160 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 18214
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 18215 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 18274
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 18275 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 18334
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 18335 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18394
Query: 1605 TV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
V +Y++ + N G + V P P + LK T VT W
Sbjct: 18395 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18452
Query: 1654 PPNVQLTGYRVR--VTPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYA 1704
PP +Q G + + K +T + +++ + + V+ L+ +Y V+ Y
Sbjct: 18453 PP-LQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 18511
Query: 1705 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVP 1760
+ + L S P + PP V+ T+ ++ ++W + I G+ ++
Sbjct: 18512 IGEPLESGPVT-ACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD 18570
Query: 1761 ANG--QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDAST 1811
G T + D+R +TGL G Y+ + N P DA
Sbjct: 18571 KEGVRWTKCNKKTLTDLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY 18629
Query: 1812 AIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV-- 1865
PSN + T+ +S+ ++W P A + GY+++ K + P G+
Sbjct: 18630 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQG 18688
Query: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ T+T L+ TEY + A+ + EP
Sbjct: 18689 KQFTVTKLKENTEYNFRICAINSEGVGEP 18717
Score = 102 bits (254), Expect = 4e-21
Identities = 337/1641 (20%), Positives = 581/1641 (35%), Gaps = 234/1641 (14%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 17141 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17199
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 17200 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17248
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 17249 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17308
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 17309 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17365
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 17366 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17425
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 17426 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17478
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 17479 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17535
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 17536 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17593
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 17594 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17652
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 17653 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17712
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 17713 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17767
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 17768 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17827
Query: 1258 PIS--DTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEED 1310
P+ D + A PP P + T++ + + W P + ++V P K E
Sbjct: 17828 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEK 17886
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
+ ++ S NAVV T L G EY V + E+ G P + +
Sbjct: 17887 WSIVAESKVCNAVV-TGLSSGQEYQFRVKAYNEK------------GKSDPRVLGVP-VI 17932
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPE-----HFSGRPR------EDRVPHSRNSITLTNLT 1419
A T+ + + Y I+ + GRPR +D P + + T
Sbjct: 17933 AKDLTIQ-PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEET 17991
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVA---------------ATPTSL 1464
T V+ I N + + ++ +L V+ + +
Sbjct: 17992 -ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 18050
Query: 1465 LISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
+ISW+ PA T + Y + +T + + +++T I+ LK G +Y ++A
Sbjct: 18051 VISWEPPAYTGGCQISNYIVEKRDTT-TTTWHMVSATVARTTIKITKLKTGTEYQFRIFA 18109
Query: 1521 VTGRGDS-PASSKPISINYR-TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S P SK + + Y E P VT + + + V+W + + GY +
Sbjct: 18110 ENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHL 18169
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
KN K T+ GL +EY V A+N G +P +
Sbjct: 18170 EQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 18229
Query: 1635 PTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSS 1686
P D + +T +++ +W P ++TGY V MK +
Sbjct: 18230 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18289
Query: 1687 VVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR--------VTDA 1735
VSGL+ +YE V A S P+ G +T + + P + V A
Sbjct: 18290 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 18349
Query: 1736 TET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYL 1793
ET + R K + D +T + IK ++ T+ TD Y+
Sbjct: 18350 GETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408
Query: 1794 YTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARITGYIIK 1846
L++ +S P+ + P L+ T ++W PP A I+ YII+
Sbjct: 18409 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 18468
Query: 1847 YEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQ 1906
+ V + +T L PG EY V+A+ EPL + P
Sbjct: 18469 KRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL------ESGPV 18521
Query: 1907 LVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHG 1966
P+ P +V + + + VT G ++ G ++ ++ G
Sbjct: 18522 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR--------DKEG 18573
Query: 1967 FRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH----LYPHGP 2013
R T T T +R R Y V E +G V Y LYP GP
Sbjct: 18574 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGP 18633
Query: 2014 GLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRVPG-TSTSA 2067
NP + + S +++W+ P D Y++ DE G
Sbjct: 18634 PSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQF 18691
Query: 2068 TLTGLTRGATYNIIVEALKDQ 2088
T+T L YN + A+ +
Sbjct: 18692 TVTKLKENTEYNFRICAINSE 18712
Score = 101 bits (252), Expect = 7e-21
Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21794 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21852
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21853 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21900
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21901 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21960
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 21961 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22020
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 22021 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22079
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 22080 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22135
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22136 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22194
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22195 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22252
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22253 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22307
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22308 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22367
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22368 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22427
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 22428 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22484
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 22485 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22543
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22601
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 22602 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22659
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 22660 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22719
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 22720 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22776
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 22777 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22824
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
+ YVV+ V A N G ES+P+V TIP+P + T +
Sbjct: 22825 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22884
Query: 1649 SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
QWT P +++ Y V K + ++ + D + + V+ LM Y+
Sbjct: 22885 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 22941
Query: 1701 SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
V A+ S P A ++ E PP RV D T+ +I+++W
Sbjct: 22942 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 22990
Score = 101 bits (251), Expect = 1e-20
Identities = 277/1345 (20%), Positives = 482/1345 (35%), Gaps = 189/1345 (14%)
Query: 692 VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
V R+D +T T ++ T + +P + VTEIT S ++W +
Sbjct: 16631 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 16690
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
+ + VE E Y + + S I L G Y V +E G
Sbjct: 16691 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 16747
Query: 803 LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
+ + P P TVD V S+ + W++P+ I Y ++ +E
Sbjct: 16748 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 16806
Query: 860 ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
E A +++L G +Y + AV E S P +VI+ + S
Sbjct: 16807 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16866
Query: 905 DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
+V +DL+ +EV K TI WT D +P+ Q I+
Sbjct: 16867 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 16909
Query: 962 AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
++T LS T+ Y A G+++ + K D P ++F + + ++
Sbjct: 16910 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 16969
Query: 1015 VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
+ W PP QIT Y + T + + + + L+ +EY + A
Sbjct: 16970 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 17029
Query: 1071 --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
G ES + +PG P+ T +++ ++VI W +P IG+ L
Sbjct: 17030 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 17089
Query: 1120 RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
+ + + + D+ L G+EY + + V + + + +
Sbjct: 17090 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 17148
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
P P + ++ N +T+ W + ITGY + P S V+
Sbjct: 17149 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17204
Query: 1226 HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
++ T L+ Y V K + PI+ + +P + P D
Sbjct: 17205 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 17261
Query: 1273 LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
N G +T R V P P+I+ K E+ A I +D +L
Sbjct: 17262 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 17314
Query: 1326 -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
+ G +Y++ S+V +S P+ + P G + + +T+ ++ W +P
Sbjct: 17315 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 17372
Query: 1384 TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR----- 1434
G I H+ + + R V NS+ +T L G EYV I+A+N
Sbjct: 17373 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17432
Query: 1435 -EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
E +P+L+ + P+ LEV S+ + W+ P I Y E S ++
Sbjct: 17433 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 17492
Query: 1493 EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
+ T ++GL +Y V A G S P ++ Y+ +
Sbjct: 17493 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 17550
Query: 1545 PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG-PTKTKTAGPDQTEMTI 1599
P+ + D NSI++ W S + GY V + T G T I
Sbjct: 17551 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 17610
Query: 1600 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
L EY + V A N G + T+V P D + L ++ V
Sbjct: 17611 SKLTEHQEYKIRVCALNKVGLGEA---TSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 17665
Query: 1660 TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
G R+ K P EI + + + V + + T+ + + L
Sbjct: 17666 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 17725
Query: 1706 KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
+++ S+ A V L+ PP+ V + + + + W + + +D +
Sbjct: 17726 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 17785
Query: 1762 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
+ + K S+ + L G Y + N+ PV +DA A + PS
Sbjct: 17786 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 17845
Query: 1818 --NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
L ++ T SL+ W+ P +R+ GY+++ + G+ +V + V A +T
Sbjct: 17846 KVTLTDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVT 17901
Query: 1872 GLEPGTEYTIYVIALKNNQKSEPLI 1896
GL G EY V A KS+P +
Sbjct: 17902 GLSSGQEYQFRVKAYNEKGKSDPRV 17926
Score = 98.6 bits (244), Expect = 6e-20
Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 18906 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18963
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 18964 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19014
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 19015 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19071
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 19072 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19128
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 19129 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19188
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 19189 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19242
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 19243 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19301
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 19302 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19359
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 19360 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19410
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 19411 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19467
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 19468 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19526
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 19527 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19584
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 19585 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19644
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 19645 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19703
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 19704 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19761
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 19762 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19817
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19873
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 19874 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19928
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 19929 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19987
Query: 1621 SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
P +T P+P + L T ++ S+S W P ++ Y V K +
Sbjct: 19988 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20047
Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
+K S+ VVSGL ++Y V+A S P + ++ L E + PP
Sbjct: 20048 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 20105
Query: 1729 ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
R + I IS + + F + N ++
Sbjct: 20106 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 20165
Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
++ D Y IT K ++ + VV+D P + + T S
Sbjct: 20166 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 20214
Query: 1829 LLVSWQPPR----ARITGYII 1845
+ + W+PP+ +++T YI+
Sbjct: 20215 VTLKWEPPKYDGGSQVTNYIL 20235
Score = 98.2 bits (243), Expect = 8e-20
Identities = 256/1304 (19%), Positives = 463/1304 (35%), Gaps = 171/1304 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13134 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13193
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13194 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13241
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13242 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13299
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13300 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13351
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13412 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13463
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13464 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13522
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13523 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13580
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13581 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13640
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13641 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13701 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13758
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 13759 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13816
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 13817 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13874
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 13875 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 13934
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 13935 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 13990
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 13991 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 14047
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 14048 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 14107
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 14108 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14167
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTTI-----PAPTDL-KFTQVTPTSLSAQWTPP--- 1655
EY+ V A N G+ +P+ V + P P + + + VT + + W P
Sbjct: 14168 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14226
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++TGY V K+ ++ I V+GL + YE V A P+
Sbjct: 14227 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14286
Query: 1715 QGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1765
+ + L PP VTD T+ + +++W ITG+ V+ +
Sbjct: 14287 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEA 14346
Query: 1766 PIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
I+ T +R + + LQ Y + +ND P VI
Sbjct: 14347 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14390
Score = 97.4 bits (241), Expect = 1e-19
Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
T +VT L G Y F+V V+ +PL + LD PT+L+ + T ++
Sbjct: 19568 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19627
Query: 1014 LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
+ W+ P + +I+GY + RR + V V+K P+ +L+ S
Sbjct: 19628 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 19681
Query: 1061 EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
EY V G ++ SP P P + +TTI I W A
Sbjct: 19682 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 19741
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
P G+ + + S + + S G+ +SGLT G EYV+ ++ + D +
Sbjct: 19742 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19801
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
P + K P ++ E V +TV + P++ + + P +
Sbjct: 19802 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 19856
Query: 1218 GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + + ++S T +N + +Y +++ V S+ + ++ PPT++
Sbjct: 19857 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 19914
Query: 1276 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
++ ++ ++W P + +PVKN E + +S ++N + +T
Sbjct: 19915 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 19967
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
NL G Y VS E P ++ + P + + I+ +S ++ W+ P
Sbjct: 19968 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 20027
Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
G RI H+ + +++ V + T ++ L +EY + A N S
Sbjct: 20028 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20086
Query: 1438 -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
P+LI +Q ++ P V A + D P ++T G
Sbjct: 20087 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 20143
Query: 1488 N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
F + TI+ LK V Y +T S + I+I +D+P
Sbjct: 20144 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 20199
Query: 1547 Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
+ ++D+ + S+++KW P S VT Y + + T+ +A +T M
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 20258
Query: 1599 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
+ L EY + A+N G S + VT T P P + T VT S++ W
Sbjct: 20259 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 20318
Query: 1653 TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
P + GY + + + K L ++ V+ + YE VYA
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 20378
Query: 1709 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
+P+ V ++ PPR R+TD ++ ++++SW+ ITG+ V+ +P
Sbjct: 20379 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 20438
Query: 1761 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
T T + + + I+GL + Y+ ++ N + + V+ T ID+
Sbjct: 20439 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 20494
Score = 96.3 bits (238), Expect = 3e-19
Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 7126 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7184
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 7185 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7244
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 7245 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7304
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 7305 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7364
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 7365 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7423
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 7424 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7483
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 7484 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7543
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 7544 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7602
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 7603 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7659
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 7660 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7719
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 7720 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7778
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7838
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 7839 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7898
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 7899 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7946
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 7947 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8002
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 8003 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8062
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
M + + +E SV A +N G + + V +P P D+K + +T +
Sbjct: 8063 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8122
Query: 1647 SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
S W PP T V + + G I + + S V L+ +Y V
Sbjct: 8123 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8182
Query: 1704 ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
A+ ++ G L+N PP V + T +TI+W+
Sbjct: 8183 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 8237
Query: 1750 TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
I G+ ++ + A G+ +R + + +YT GL+ G +Y+ + +++ +R+
Sbjct: 8238 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 8296
Query: 1803 SPVVIDASTAIDAP 1816
+P A IDAP
Sbjct: 8297 TPPT-KAVDPIDAP 8309
Score = 94.4 bits (233), Expect = 1e-18
Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 12328 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12385
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 12386 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12433
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 12434 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12493
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 12494 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12553
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 12554 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12613
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 12614 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12665
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 12666 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12725
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 12726 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12783
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
L EY+ + A+ SP K T T P PP E VT++T+ + W P
Sbjct: 12784 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12841
Query: 1110 APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
G K+ G + + AP ++ + +GL +Y +
Sbjct: 12842 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12899
Query: 1152 -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
TI D + K + + TN+ L+A + TVSW++
Sbjct: 12900 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 12959
Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
T P G + + ++ CT + N +Y ++
Sbjct: 12960 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13004
Query: 1254 KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
K S I ++ PP ++ + D ++W PP ++TN++V + +
Sbjct: 13005 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 13062
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
A++S + + + L+ G EY + + + P+ K D P D
Sbjct: 13063 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 13122
Query: 1366 -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
S+IT + TV W P + ITGY + + +R P ++ T L
Sbjct: 13123 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13182
Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
GTEY + A+N + P G+ S S P +V T +S+ +SW
Sbjct: 13183 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13237
Query: 1469 DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
PA + Y + ++ V+ +P + K+ ++GL Y VYAV
Sbjct: 13238 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13296
Query: 1523 GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
G D P P I E + + ++ T + ++++ PV G
Sbjct: 13297 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13353
Query: 1578 PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
+ P G D T + E + +Y++++ +N G+ + + V
Sbjct: 13354 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13411
Query: 1630 TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
P P ++ +++ S W PP + + Y V+ E+ +
Sbjct: 13412 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 13470
Query: 1685 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
+S V+ L Y V+A + P + V + P +V ++++ +I
Sbjct: 13471 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 13530
Query: 1743 SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
W+ I G+ VD + + QR +K Y+ L G +Y + N+
Sbjct: 13531 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 13588
Query: 1799 NARSSP--VVIDASTAIDAP 1816
N +P + + A + AP
Sbjct: 13589 NGEGTPSEITVVARDDVVAP 13608
Score = 94.0 bits (232), Expect = 2e-18
Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)
Query: 710 TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
TV+ TP P+ E +I +S + W D + Y L ++ + +++
Sbjct: 8423 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 8479
Query: 767 DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
+ ST ++ L+ G++Y+ V + G +++ PDAP P V
Sbjct: 8480 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8539
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
+ V S++V+W+ P+ +PI GY + E +ST + + L G+
Sbjct: 8540 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 8596
Query: 877 NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
+T ++ V + P + D + P P + + + + + W PP
Sbjct: 8597 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 8656
Query: 932 --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ GY VD ++ N +++ + + T E+ G Y +V AV+ E
Sbjct: 8657 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 8713
Query: 987 KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
P Q T +LD T+ + WT ++
Sbjct: 8714 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 8773
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
R+ + NVG + K LR + Y ++ G++ + V
Sbjct: 8774 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 8821
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
F P + P T ++ W+ + GF + + ++ + + ++
Sbjct: 8822 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 8879
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
++GL G EY + +V+ + P V V PL PPT+ + E
Sbjct: 8880 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 8937
Query: 1188 TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
T +T+ W+ + I GY I + + + + +S +NL Y
Sbjct: 8938 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 8994
Query: 1245 VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
V V + ES +P++ I PPT ++ DT++V P I D+T
Sbjct: 8995 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 9054
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
+ E V E P+D + + +E +S +V E + + +
Sbjct: 9055 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 9111
Query: 1357 GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
G P + +DI A S + W AP G I H+ + + R
Sbjct: 9112 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 9170
Query: 1402 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
+ + + ++ + L P +Y + A+N S + + D P
Sbjct: 9171 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 9230
Query: 1452 RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
+V+A T S+L+SW P + Y + E G +P+ + + G +
Sbjct: 9231 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 9290
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
+ L GV Y A+ G P S S P ++ + PS +V D +S
Sbjct: 9291 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 9348
Query: 1558 ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
IS+ W P + SP+ GY V + G T K PD+ T E + P ++ Y
Sbjct: 9349 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 9405
Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
V A N +GES+P T IPA TD++ + AQ V G ++R+
Sbjct: 9406 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 9460
Query: 1667 ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
TPK E G K ++ A +SS +++ + + S+
Sbjct: 9461 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 9520
Query: 1704 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
A K+ + A V ++ PP+ +V+D T + +SW+ + I G+ ++
Sbjct: 9521 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 9579
Query: 1760 PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
+G+ + + PD S T + L Y + N PV I +TA D
Sbjct: 9580 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 9637
Query: 1816 -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
P L+ T N++ +SW+PP+ + +T YI++ ++ G+ +
Sbjct: 9638 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 9697
Query: 1864 GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
V E T+ L G EY V A+ S+P
Sbjct: 9698 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9730
Score = 93.6 bits (231), Expect = 2e-18
Identities = 266/1257 (21%), Positives = 449/1257 (35%), Gaps = 180/1257 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 21048 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21107
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 21108 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21166
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 21167 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21221
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 21222 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21279
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 21280 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21339
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 21340 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21399
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 21400 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21459
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 21460 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21517
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 21518 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 21573 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21627
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 21628 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21684
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 21685 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21742
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 21743 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21802
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 21803 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21850
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P+ ++VTD ++S++W
Sbjct: 21851 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21910
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 21911 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21970
Query: 1627 T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
T AV + AP D F Q A +++L Y+ R TP + P
Sbjct: 21971 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 22025
Query: 1678 INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
++L D ++ S L V A KY ++V ++ S+ V L+ PP
Sbjct: 22026 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 22082
Query: 1730 ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
D T + T+ W I + V+ A+ ++ + K + + + L
Sbjct: 22083 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 22142
Query: 1786 GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
G Y + +N+ P I A+ P L + T+ +S +++W P
Sbjct: 22143 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 22202
Query: 1838 ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+RITGY+++ + GS V T+ L TEY V A + SEP
Sbjct: 22203 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 22257
Score = 92.8 bits (229), Expect = 3e-18
Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20196 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20255
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20256 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20313
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20314 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20372
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20373 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20431
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20432 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20488
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20489 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20548
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20549 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20608
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20609 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20665
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 20666 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20725
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 20726 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20785
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 20786 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20841
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 20842 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20901
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 20902 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20957
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 20958 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21012
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 21013 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21070
Query: 1616 NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
N G +P T +PAP DL T TS+ WT P+ +T Y V
Sbjct: 21071 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21130
Query: 1668 PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
K E+T I+ + + VS L + E V+A + S P G +T E +
Sbjct: 21131 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 21187
Query: 1726 PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
P + V + + ++ K + + D +P ++ +T
Sbjct: 21188 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 21247
Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
S + G Y + L DNA V + PS +RF +S++
Sbjct: 21248 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 21303
Query: 1831 VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
+SW P IT Y I+ + ++V T + L EY V A
Sbjct: 21304 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 21362
Query: 1887 KNNQKSEPLI 1896
S+PL+
Sbjct: 21363 NRYGVSQPLV 21372
Score = 91.3 bits (225), Expect = 1e-17
Identities = 267/1256 (21%), Positives = 445/1256 (35%), Gaps = 161/1256 (12%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
S+ + T +S ++SW EY + +G Q + + I ++ ++
Sbjct: 21098 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 21156
Query: 787 IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
V +++ E+ L ++ T + P VD D + VR Y+
Sbjct: 21157 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 21216
Query: 843 IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
PS+ L L E T N +TLS ++ + +N V
Sbjct: 21217 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 21276
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
I T G P P ++F E+ V + W PE +T Y ++ +
Sbjct: 21277 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21332
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
++R TF +V L Y F+V A + S+PL A+ ++ P
Sbjct: 21333 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 21391
Query: 1005 FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
+ N T + + W P +++TG+ + ++ N P S +Y L
Sbjct: 21392 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 21451
Query: 1059 ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
+Y + A SP FT P P +VT TI + W P R G
Sbjct: 21452 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 21511
Query: 1116 K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
+ QG E R V + + V+GL+PG Y + I I
Sbjct: 21512 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 21557
Query: 1167 VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
V +SPP+ +E P+ G++ S E + R
Sbjct: 21558 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21617
Query: 1212 PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
T + G +E+ ++ D T + + VYTV+ S V +
Sbjct: 21618 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
DT V P +RFTNI + M + W P + +T++++ ED
Sbjct: 21678 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 21734
Query: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
E + S A+ L N G EY VS+V + PL Q T D+P +
Sbjct: 21735 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21788
Query: 1367 SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
S+IT NS T+ W P + I Y + + + + + P S +T LT G
Sbjct: 21789 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21848
Query: 1422 TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
EY ++A N P LI + V+ P ++V + T++ + W P
Sbjct: 21849 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21908
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
I Y + + ++ + K+ T++ L+ G +Y V A+ G+GDS
Sbjct: 21909 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 21968
Query: 1528 --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
+ K + E+D + + T V S++ ++ T V + P +
Sbjct: 21969 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 22028
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
+ +T+E ++ +N SG V P P + F V
Sbjct: 22029 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 22088
Query: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
T S + W P + G R+ EK + I+ V+ L Y
Sbjct: 22089 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22147
Query: 1700 VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
V A+ + P + + E +PPRR V D ++++ ++W ITG
Sbjct: 22148 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 22207
Query: 1754 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
+ ++ ++ + ++T+ L T+Y+ + ND S P +S I
Sbjct: 22208 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22266
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1866
P P + L IT +I K GSP VP RP P VT
Sbjct: 22267 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22308
Score = 90.1 bits (222), Expect = 2e-17
Identities = 140/634 (22%), Positives = 237/634 (37%), Gaps = 93/634 (14%)
Query: 1358 LDSPTG---IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHS 1409
LDSP + S +T T+ W P+ A IT Y + R + E P
Sbjct: 22766 LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTL 22825
Query: 1410 RNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S +T L EY+ + A+N E P++ T+ P E V
Sbjct: 22826 --SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH 22883
Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT-----------------IS 1506
++I W P E+ G + + + V + + ++
Sbjct: 22884 IIIQWTKP------------ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVT 22931
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWL 1563
L G DY V AV G+S S I+ R PS +V D +SIS+ W
Sbjct: 22932 SLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 22991
Query: 1564 P----SSSPVTGYRVTTTPKNGPGPTKTKT-AGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
+ + GY + K+ + T A TE T+ L+ +Y V A N
Sbjct: 22992 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 23051
Query: 1619 G---------ESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1669
G E +P+ + + + DLK T S + V ++G V
Sbjct: 23052 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM---VSVSGRPPPVITW 23108
Query: 1670 EKTG---PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS--RPAQGVVTTLENV 1724
K G + I +S S+++ + +Y+ Y ++ S + A +V +
Sbjct: 23109 SKQGIDLASRAIIDTTESYSLLIVDKV--NRYDAGKYTIEAENQSGKKSATVLVKVYDTP 23166
Query: 1725 SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
P +V + + ++TI+W T + + V+ A + T K Y I
Sbjct: 23167 GPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRI 23226
Query: 1781 TGLQPGTDYKIY-----LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP 1835
+GL GT Y +Y + + +S V+ + + P+ L + T +++ ++W+
Sbjct: 23227 SGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEK 23285
Query: 1836 PR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1891
P +R+TGY+++ K G+ V +P V E T+T L G +Y + A
Sbjct: 23286 PLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGV 23345
Query: 1892 SEP-----LIGRKKTDELP--QLVTLPHPNLHGP 1918
SEP + + LP L T+P +H P
Sbjct: 23346 SEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 23379
Score = 89.7 bits (221), Expect = 3e-17
Identities = 131/594 (22%), Positives = 227/594 (38%), Gaps = 77/594 (12%)
Query: 1414 TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
T+T L G EY+ + A N ++P+ + V P ++ + +
Sbjct: 6777 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 6836
Query: 1466 ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
++W+ P + Y I + TV +AT++ + G +Y+ V A
Sbjct: 6837 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 6896
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S+ + I++PS + +D +S+ +KW P SP+ GY +
Sbjct: 6897 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6956
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
+ + + + GL+ +Y+ V A+N +G S P + I
Sbjct: 6957 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 7010
Query: 1635 PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
P V PT LSA + PN V TGY R T +TG +
Sbjct: 7011 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7070
Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
+ + +V+S + + + +Y LK + G V + S P+ + D
Sbjct: 7071 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 7127
Query: 1736 TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
T+ ++ ++W + +TG+ V+ + +T + +T+ L G +Y
Sbjct: 7128 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 7187
Query: 1792 YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
+ N P +D +T D P N+++ T NS+ ++W PP+ +RI
Sbjct: 7188 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 7247
Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
GYI++ GS P T+ +TGLE G Y V AL S+P +
Sbjct: 7248 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRP 7303
Query: 1901 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQP 1954
T+E+ + T P + LDV T G I+LP T +P
Sbjct: 7304 TEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTGKP 7346
Score = 89.4 bits (220), Expect = 4e-17
Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)
Query: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
S P E+ E P+ P S P+ + K+I + W+P KN +G E G
Sbjct: 7898 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 7955
Query: 662 -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
+NS IK LK GVV + + + ++ G E + + P
Sbjct: 7956 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 8014
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
T+ ET + S+ + + V VS + L+ + D
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 8067
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ + +P + I + ++ G + ++ P D + +S
Sbjct: 8068 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8125
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
+ W P+ PI Y + + + + E S T+ DL P +Y + AV
Sbjct: 8126 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 8185
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
+ + ++ P D++ T +TI W PP S + GY ++
Sbjct: 8186 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 8245
Query: 941 VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
I GE + +PI T GL G Y F+V A + S+P A
Sbjct: 8246 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 8299
Query: 995 TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
TK +DAP T+L+ V D L + W I +
Sbjct: 8300 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 8358
Query: 1032 GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
L RR Q + V P + + N + Y + + G
Sbjct: 8359 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 8418
Query: 1074 ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
++P V T PG I ++ +T+++ W P G + + E +
Sbjct: 8419 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 8474
Query: 1134 DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
DS IVV+ L G EY++ ++ + P V+K + P PP
Sbjct: 8475 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 8533
Query: 1179 -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
+ + + + + V W + I GY + N + + + + + D
Sbjct: 8534 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 8592
Query: 1236 NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
L GL Y V + P SD P PP P R T+ T+ + W P
Sbjct: 8593 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8652
Query: 1290 PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
P ++ + V V E + + G +Y + VS+V E
Sbjct: 8653 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8712
Query: 1347 STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
P + T + P ++ + + G +R P +GRP
Sbjct: 8713 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 8763
Query: 1405 RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
+V ++ + + N+ +E ++ I A N + V
Sbjct: 8764 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 8821
Query: 1448 SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
DVP DL+ V L++W P E G S + F +
Sbjct: 8822 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 8869
Query: 1500 ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
+S I+GL G +Y V A G P P+ I +D
Sbjct: 8870 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 8925
Query: 1545 PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
P ++ T+ ++I++ W SP+ GY + + P + T +E
Sbjct: 8926 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 8985
Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
L Y V A N GES+P ++P ++ +V PT LS + V
Sbjct: 8986 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 9038
Query: 1658 QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
+ G V + P + TG PM +I + + + + + + TK EVS V
Sbjct: 9039 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096
Query: 1703 YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
K T T + + + NV SPPR VTD + ++W +
Sbjct: 9097 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 9156
Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
IT + +D A+ + + + Y I L P Y+ + Y ++D +S
Sbjct: 9157 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 9216
Query: 1804 PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
VVI D P + LA T S+LVSW PP + ITGY ++ + GSP V
Sbjct: 9217 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 9276
Query: 1859 PRPRPGVTEATITGLE 1874
R +T+ + G+E
Sbjct: 9277 --SRAPITKVGLKGVE 9290
Score = 89.4 bits (220), Expect = 4e-17
Identities = 289/1431 (20%), Positives = 507/1431 (35%), Gaps = 177/1431 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ P++ P ++ + + NS + W P+ S I +YI+ +
Sbjct: 16741 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 16798
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K+S +W E L + I L G Y +++++ + G + S + P+
Sbjct: 16799 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 16849
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E + S V + +S T++ + L +
Sbjct: 16850 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 16908
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
L T S+ G +Y + V + G+++ + PD P P D V
Sbjct: 16909 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 16966
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
SI + W+ P IT Y + + ++ ++ ++ L+ G +Y I+
Sbjct: 16967 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 17026
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
A EN+ ++ + P P F ++ + I W P S V G
Sbjct: 17027 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 17084
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
Y ++ N I +T + L G+ Y F+V+A V G+ SK
Sbjct: 17085 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 17144
Query: 994 TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
D P + + + + ++WT P + ITGY + G+ + + +
Sbjct: 17145 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17204
Query: 1049 -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
+++ + L Y ++A G P +TG T P S+ P + +
Sbjct: 17205 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 17261
Query: 1101 TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
T +V + P P I + G + + + T ++V
Sbjct: 17262 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17321
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
Y ++ + P+ KV+ PP + +++W + DI+
Sbjct: 17322 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 17381
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
Y + T+ + V + T L G EY V+ Y V + ES P+
Sbjct: 17382 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17439
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
+ ++P PP L TNI D+M V W P S + + ++ + + +
Sbjct: 17440 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 17497
Query: 1318 P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
+D + +T L EY VS + E +P K PT
Sbjct: 17498 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 17557
Query: 1368 DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
D T NS T+ W P + I GY + E E ++ + + +T L
Sbjct: 17558 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 17613
Query: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
T EY + + ALN + +G+ ++V + + + A P L S + VR
Sbjct: 17614 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 17667
Query: 1477 -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
RI G +P ++ + T + ++ GV+YT Y +
Sbjct: 17668 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 17726
Query: 1525 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
S + S +++ P + V +V+ +S + W P + V Y +
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 17786
Query: 1581 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
++ +T +E L Y V A+N G P+ V+ A P P
Sbjct: 17787 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 17844
Query: 1636 TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
+ T V+ TS S W P ++ GY V + PK EK + E + + VV
Sbjct: 17845 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 17900
Query: 1690 SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
+GL +Y+ V A + S P GV +T ++ P A E
Sbjct: 17901 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 17960
Query: 1738 ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
ISW E + T V+ + I+ K D YT+T
Sbjct: 17961 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 18019
Query: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
T +N S +V++ P +RF + + +++SW+PP +I+ YI
Sbjct: 18020 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 18069
Query: 1845 IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
++ + +V T IT L+ GTEY + A KS PL
Sbjct: 18070 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPL 18119
Score = 89.4 bits (220), Expect = 4e-17
Identities = 339/1648 (20%), Positives = 590/1648 (35%), Gaps = 249/1648 (15%)
Query: 611 PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
P + TE P+ P +S + W P S I+ Y+L R K S W EA
Sbjct: 22165 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22223
Query: 658 TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
GH ++T++ L YE ++ + G+ E R F++ P T +TG
Sbjct: 22224 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22279
Query: 714 ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
T A S ++ S V+ +++E +E D + T
Sbjct: 22280 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22331
Query: 774 SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
++ + D + G +Y + + + G ++ ++ P P V V S V+
Sbjct: 22332 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22389
Query: 831 WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
W P+ IT Y + S + +N + ++ L ++Y+ + +
Sbjct: 22390 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22449
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
V + ES P++ + P + T P + V+ ++I W P S + GY
Sbjct: 22450 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22503
Query: 938 RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
V+ N + ++P + +VTGL G+ Y F+ +A VS E S+P+
Sbjct: 22504 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22562
Query: 991 AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
AQ +DAP + + T STV + W+ P +++ GY +
Sbjct: 22563 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22620
Query: 1030 ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
TV G ++ V ++K + SE T V + PKA
Sbjct: 22621 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22676
Query: 1080 -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
G T++ GS + + P P+I + G + E + T
Sbjct: 22677 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22728
Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
+ V+ YT+ V + ++ KV+ P L + + T+
Sbjct: 22729 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22787
Query: 1194 SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
+W S + G IT ++ + L V+ S L EY V V
Sbjct: 22788 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22845
Query: 1251 KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
VP+ I A +P PP G + + + W P S +++N+LV
Sbjct: 22846 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22905
Query: 1301 -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
R++ V + V D + +T+L+ G +Y V++V S P
Sbjct: 22906 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22958
Query: 1354 QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
P+ D T +S ++ W P I GY + + R
Sbjct: 22959 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 23018
Query: 1403 EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
RN+ T+ +L G +Y + A+N G E I + V ++P DLE+
Sbjct: 23019 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 23077
Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
++ I A R+ +G PV ++ G A+ + + Y++
Sbjct: 23078 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23130
Query: 1518 V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
+ Y + S S + + Y T PS ++V +V +S+++ W
Sbjct: 23131 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23189
Query: 1563 -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
+ +PV Y + + KT T +T I GL Y V +N G
Sbjct: 23190 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23248
Query: 1622 QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
+P + V+ +P P L+ VT ++++ W P +LTGY +
Sbjct: 23249 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23308
Query: 1674 PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
MK + L P V+ L +Y E V ++T+T+ Q V+ T++
Sbjct: 23309 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 23368
Query: 1724 VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
+ P++ A E I I+ R F + + + ++ K +
Sbjct: 23369 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 23428
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
T ++ +Y + L + + VI ++ S+ +SW+PP
Sbjct: 23429 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 23488
Query: 1838 -ARITGYIIKY---EKPG-SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
A ++GY+++ +PG P E V R + T L G EY V A N+
Sbjct: 23489 GAPLSGYVVEQRDAHRPGWLPVSESVTR-----STFKFTRLTEGNEYVFRVAA--TNRFG 23541
Query: 1893 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSG 1951
+ + E + +P P PE L + + +T +P D G G Q+ G
Sbjct: 23542 IGSYLQSEVIECRSSIRIPGP----PETLQIFDVSRDGMTLTWYPPEDDG-GSQVTGY-- 23594
Query: 1952 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPH 2011
V ++ + + R P T T R+R + E ++ I P
Sbjct: 23595 ---IVERKEVRADRWVRVNKVPVTMT--RYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 23649
Query: 2012 GP--GLNPNASTGQEALSQTT--------ISWAPFQD-----TSEYIISCHPVGTDEEPL 2056
P ++P A G+ + T ++W+ +D + Y+I V E
Sbjct: 23650 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 23709
Query: 2057 QFRVPGTSTSATLTGLTRGATYNIIVEA 2084
P TLT L +GA Y V A
Sbjct: 23710 CNTTPTKIREYTLTHLPQGAEYRFRVLA 23737
Score = 88.2 bits (217), Expect = 8e-17
Identities = 177/778 (22%), Positives = 292/778 (37%), Gaps = 127/778 (16%)
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
T ++L G EY V V S P + D P +PP DL+ TN+
Sbjct: 9705 TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9764
Query: 1279 -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
G +TW APP D PV + V +L + + V+ +
Sbjct: 9765 VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9818
Query: 1332 TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
T + +V+++ + L + G P G I F ++A+ T+ W P+ +
Sbjct: 9819 TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9876
Query: 1385 ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
IT Y I H S P+E + T+ L G EYV I+A N
Sbjct: 9877 ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9929
Query: 1435 --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
+ P +V P V + T S+ ++W+ P V Y + +T
Sbjct: 9930 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9989
Query: 1489 -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
P++ T+ S ++GL G DY VYA+ G PAS S P +
Sbjct: 9990 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 10046
Query: 1540 TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
P +VTD +S ++W P S VTGY V + K K T
Sbjct: 10047 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10106
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
++ + GL+ Y V A N +G +P T V ++K V+P L A
Sbjct: 10107 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 10160
Query: 1655 PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10220
Query: 1703 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10280
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10281 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10338
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10339 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10398
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 1916
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10399 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10449
Score = 84.7 bits (208), Expect = 9e-16
Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 6814 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6873
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 6874 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6928
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 6929 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6988
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 6989 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7048
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 7049 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7104
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 7105 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7159
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 7160 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7219
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 7220 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7277
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
L G Y V + S P T I AV
Sbjct: 7278 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7336
Query: 1272 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
+L T G ++TW I + + V + V + SD G
Sbjct: 7337 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 7387
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
T + +V+ + K G P D +D+T S + W PR + IT
Sbjct: 7388 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7445
Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
Y + R + V H +S T L P EY+ + A N +
Sbjct: 7446 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 7498
Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
SP+ Q P LE T ++ ++W P + Y + + + V
Sbjct: 7499 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7558
Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
+ +P +T + GL Y V A + G G S++PI I + ID P
Sbjct: 7559 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 7616
Query: 1547 QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
+ V DV S+ + W + + Y V K G G T+ + GL
Sbjct: 7617 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 7675
Query: 1603 QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
EY V A N +GES+P L + + P L+ +T + +WT P
Sbjct: 7676 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 7735
Query: 1656 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
+T Y V + G + ++ + V+ L E S+Y + +
Sbjct: 7736 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 7789
Query: 1712 RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
Q T +E+ PP V D T+ + + W I + ++
Sbjct: 7790 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 7849
Query: 1758 AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
G ++ +T PD ++ +T + GT+ + + N+ P + D
Sbjct: 7850 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 7908
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
++ P +L + ++W+PP + I GY ++ G+ V RP
Sbjct: 7909 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7968
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ G+ P EY + V A+ SEP
Sbjct: 7969 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7999
Score = 83.6 bits (205), Expect = 2e-15
Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 15978 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16037
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 16038 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16082
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 16083 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16142
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 16143 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16200
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 16201 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16254
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 16255 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16311
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 16312 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16371
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 16372 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16430
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 16431 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16490
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 16491 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16550
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 16551 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16607
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 16608 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16662
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 16663 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16721
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 16722 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16781
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 16782 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16839
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 16840 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16897
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 16898 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16949
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 16950 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17009
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
+ + L+ EY ++A+N G ES P+V P P F T ++
Sbjct: 17010 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17063
Query: 1645 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
S+ QW P + GY + + K + L +YE
Sbjct: 17064 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17123
Query: 1701 SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
VYA + ++ + PP IT+ W ITG+
Sbjct: 17124 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17183
Query: 1755 QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
V+ P R +K + +T++GL Y+ + N
Sbjct: 17184 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17227
Score = 82.0 bits (201), Expect = 6e-15
Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 21403 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21462
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 21463 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21507
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 21508 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21567
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 21568 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21622
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 21623 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21681
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 21682 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21737
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 21738 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21796
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 21797 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21855
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 21856 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21914
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 21915 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21973
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 21974 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22033
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 22034 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22092
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 22093 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22151
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 22152 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22211
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 22212 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22268
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 22269 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22324
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 22325 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22376
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 22377 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
+EY V ++N G S+PL + +P APT + V+ ++S +W P
Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22495
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++ GY V + +KE + + V+GL+ +Y+ YAL S+ +
Sbjct: 22496 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22555
Query: 1715 QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
+ + V P R VTD T +T+++ W + G+ ++ P +
Sbjct: 22556 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 22615
Query: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
TI D +T+T L G Y+ + N
Sbjct: 22616 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 22648
Score = 79.3 bits (194), Expect = 4e-14
Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)
Query: 1412 SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
S +T L G EY I+A+N E P++ V D P+ EV T S++
Sbjct: 16323 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 16382
Query: 1466 ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
+ W+ PA + Y + + G + + ++GL DY V A
Sbjct: 16383 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 16442
Query: 1522 TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
G SP S+ + + + P+ +V D+ +S+ + W + GY V
Sbjct: 16443 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 16502
Query: 1575 TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
+ G T G ++T + +E L EY + A N +G + +V+
Sbjct: 16503 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 16562
Query: 1627 TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
+ DL+ ++ + R TP+ K G +++ +
Sbjct: 16563 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 16618
Query: 1683 DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
+SS L +Y+ Y L +++ ++ A V L+ SPP +VT+ T+ ++
Sbjct: 16619 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16678
Query: 1741 TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
+I+W I + V+ A ++ S+ I LQ G Y +
Sbjct: 16679 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16738
Query: 1797 NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
N+ P I + P + T NS+ +SW P ++I YI++ +
Sbjct: 16739 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16798
Query: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
S R + +A IT L G EY V+A+ +S+P
Sbjct: 16799 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 16842
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19696 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19755
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19756 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19807
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19808 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19859
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19860 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19917
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19918 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19977
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 19978 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20034
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 20035 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20088
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 20089 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20139
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20140 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20199
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20259
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20260 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20318
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20374
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 20375 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20419
Score = 75.5 bits (184), Expect = 6e-13
Identities = 200/944 (21%), Positives = 346/944 (36%), Gaps = 118/944 (12%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 15185 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 15241
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 15242 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15301
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 15302 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15361
Query: 1071 -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
+P T F T +PG PP N V +T +I I W + G+
Sbjct: 15362 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15418
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 15419 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15477
Query: 1169 KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 15478 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15536
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 15537 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15596
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E + + ++ + + + L G Y V +
Sbjct: 15597 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15655
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 15656 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15715
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V T+T L G EY + A N E + +Q +V + +
Sbjct: 15716 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15770
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 15771 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 15828
Query: 1504 --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
++ +K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 15829 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15885
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 15886 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15942
Query: 1612 VYAQNPSGE-----SQPLVQTAVTTIPAPTDLK-FTQVTPTSLSAQWTPP----NVQLTG 1661
+ A+N G+ S+P V +P P T + S+ QW P ++ G
Sbjct: 15943 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16002
Query: 1662 YRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GV 1717
Y + KE+ + ++N P + +GL +YE V A +P++
Sbjct: 16003 YHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSEC 16060
Query: 1718 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
+ PP R T ++T+ W+ T ITG+ V+
Sbjct: 16061 YVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 16104
Score = 75.1 bits (183), Expect = 7e-13
Identities = 125/581 (21%), Positives = 213/581 (36%), Gaps = 71/581 (12%)
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWD 1469
+ + N T S+ +N E + + + V D P DL+V T TS +SW
Sbjct: 12291 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVR--VLDTPGPVSDLKVSDVTKTSCHVSWA 12348
Query: 1470 AP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
P V +Y + E + T K++ ++ L PG +Y V AV G
Sbjct: 12349 PPENDGGSQVTHYIVEKREADRKT-WSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 12407
Query: 1526 DSPASSKP---ISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
+ P ++ + +E D P +++VT++ NS ++ WLP + + GY +
Sbjct: 12408 PGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 12467
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTTIPA 1634
+ P T+ + + + GL+ +Y V A+N G S P V A +
Sbjct: 12468 EEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLP 12527
Query: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
P L Q+T + G ++R+ P VV S +
Sbjct: 12528 PKILMPEQITIKA-------------GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12574
Query: 1695 ATKYE-VSVYALKD---------TLTSRPAQGV------VTTLENVSPPRRA-RVTDATE 1737
K + S+ +KD +LT+ + G V ++ PP+ ++D
Sbjct: 12575 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12634
Query: 1738 TTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
++SW E IT + V+ + + S + L PG +Y +
Sbjct: 12635 DACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRV 12694
Query: 1794 YTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGY 1843
N S P+ A P N R + + V+W P + I GY
Sbjct: 12695 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 12754
Query: 1844 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 1903
+I+ ++ S TE GL G EY+ + AL S P K T+
Sbjct: 12755 LIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPP---SKPTEY 12811
Query: 1904 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGI 1944
+ + + P PE++DV + + P +D G+ I
Sbjct: 12812 VTARMPVDPPG--KPEVIDVTKSTVSLIW-ARPKHDGGSKI 12849
Score = 72.0 bits (175), Expect = 6e-12
Identities = 284/1399 (20%), Positives = 497/1399 (35%), Gaps = 195/1399 (13%)
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
G + I+ H++ + T + P S TV+ + P V+EI S
Sbjct: 10899 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10955
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
++W D Y + E D P +ATS L G +Y+ V
Sbjct: 10956 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11014
Query: 794 SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
++ G + + A D PP P D VD T + + W++P +PITGY +
Sbjct: 11015 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11074
Query: 844 VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
Y EG+ + N ++ LQ G Y + A V T + I+ +
Sbjct: 11075 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11132
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
P S + D++ +E VK P + + G V G + +
Sbjct: 11133 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11187
Query: 957 SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
+ F+ V + + T +++ VS+ SK + A T LD P + ++ T
Sbjct: 11188 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11245
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ + W PP+ + + Y + TR+ + G S +K + +LQ EY
Sbjct: 11246 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11305
Query: 1066 LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
+ A P T + S P P T++TE ++WT +P G
Sbjct: 11306 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11365
Query: 1115 FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
+ + R G T + V+GL G Y + + G + +P + +
Sbjct: 11366 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11425
Query: 1171 ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
+ P PP N L+ + + W + + I GY + Q N + +
Sbjct: 11426 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11484
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
Q + L G EY + E P +++++I PP +L T
Sbjct: 11485 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11544
Query: 1280 PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 11545 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11602
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 11603 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11653
Query: 1382 R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
+ IT + + + + G R + NL EY + A N
Sbjct: 11654 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11711
Query: 1434 ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
++P+L P +L + T + + W P ++Y G
Sbjct: 11712 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11771
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
+ + K T + + V+ I + V + + S K + + ++ KP
Sbjct: 11772 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11829
Query: 1546 SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
V D +S V + + + R+ + P P T D T++T
Sbjct: 11830 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11879
Query: 1599 IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
I+ + ++ ++ V A N +G V P P +LK V+
Sbjct: 11880 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 11939
Query: 1647 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
+ W PP G ++ EK K + + S++V+ G V E + Y +
Sbjct: 11940 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 11997
Query: 1707 DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
++ G T + V P VT ++ +T+ W ++ITG
Sbjct: 11998 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 12057
Query: 1754 FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
+ ++ + P+ ++ P+ R + L P +Y+ + N+ + S PV
Sbjct: 12058 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 12116
Query: 1806 VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
V D P+N R + TT +S+ + W P A I GY+++ + P E
Sbjct: 12117 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12176
Query: 1859 PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 1914
R E T+T L+ EY V A NQ +G + EL + + P
Sbjct: 12177 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEI 12228
Query: 1915 LHGPEILDVPSTVQKTPFV 1933
L PEI D+ ++++K V
Sbjct: 12229 LEPPEI-DLDASMRKLVIV 12246
Score = 68.2 bits (165), Expect = 9e-11
Identities = 218/1049 (20%), Positives = 384/1049 (36%), Gaps = 174/1049 (16%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 6720 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6779
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 6780 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6837
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 6838 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6896
Query: 1251 KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
P + T V PP +L ++ ++++ W PP S L +
Sbjct: 6897 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6956
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
R K+ + + P + +T L G +Y+ VS+ + S P D
Sbjct: 6957 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7015
Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
D++A + I P +P + D+V + + + + L+
Sbjct: 7016 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 7075
Query: 1420 PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
E V+S + + L L + T+S P++L+ T S+ ++
Sbjct: 7076 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 7135
Query: 1468 WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
W+ P + G SP+ + V + + T+ L G
Sbjct: 7136 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 7183
Query: 1513 DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
+Y V A G G+ +P++++ + D P ++ D NSI + W P
Sbjct: 7184 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 7243
Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + GY V P+ G K G +T+M + GL+ Y V A N G S+P
Sbjct: 7244 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7300
Query: 1624 LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
T AV T AP L T L A T P ++T + + K
Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7360
Query: 1670 EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
+ K I + P S+V + + + + + Y ++ A VV L+
Sbjct: 7361 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 7413
Query: 1726 PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
PP +TD T + ++W + IT + V+ + + + T+K ++
Sbjct: 7414 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 7471
Query: 1780 ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
T L P +Y +Y + + ++SP I A D P+ L T +++ +
Sbjct: 7472 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 7529
Query: 1832 SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
+W P + ITGY ++ P + + T + GL +Y V+A
Sbjct: 7530 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 7589
Query: 1887 -----KNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTG 1941
K ++ +EP++ + D P P P + DV T + + T P +D G
Sbjct: 7590 LAGPGKPSKSTEPILIKDPIDP-------PWPP-GKPTVKDVGKTSVRLNW-TKPEHDGG 7640
Query: 1942 NGIQ--------------------LPGTSGQQPSV--GQQMIFEEHGFRR---TTPPTTA 1976
I+ +P T P + GQ+ F + + P +
Sbjct: 7641 AKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPS 7700
Query: 1977 TPIRHRPRPYPPNVGEEIQIGHIPREDVD 2005
P+ R + YPP+ +++ +I + D
Sbjct: 7701 DPVLCREKLYPPSPPRWLEVINITKNTAD 7729
Score = 62.8 bits (151), Expect = 4e-09
Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 20155 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20209
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 20210 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20269
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 20270 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20327
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 20328 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20384
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 20385 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20442
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 20443 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20502
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 20503 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20558
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 20559 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20618
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 20619 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20678
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 20679 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20734
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 20735 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20792
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 20793 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20851
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 20852 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20910
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 20911 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20970
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 20971 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21087
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 21088 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21144
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
T E+ + L+ V+A+N G S P+ TI P +K +TP LS
Sbjct: 21145 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 21194
Query: 1653 TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
P Q+T G+ V + K P I+ D + S + +K E + ++K+
Sbjct: 21195 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21254
Query: 1709 LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
+ V T+ + PP + R + ++ +SW +
Sbjct: 21255 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21314
Query: 1751 --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
IT + ++ QT + R ++ + L +Y+ + N S P+V
Sbjct: 21315 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21373
Query: 1808 DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
A P T + + ++W P + +TG+ ++ ++ S +
Sbjct: 21374 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 21433
Query: 1858 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V E TGL G +Y V A + S P
Sbjct: 21434 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21470
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 9120 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9177
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9178 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9230
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9231 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9284
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9285 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9344
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9345 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9404
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9405 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9436
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24354 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24408
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24409 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24468
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24469 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24528
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24529 CENLGGESEWSEISEPI--TPKSD 24550
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24737 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24794
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24795 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24854
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24855 EVDETREVSMT 24865
Score = 35.8 bits (81), Expect = 0.50
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)
Query: 1534 ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
+ + + + DKP+ V + + NS + W P + S +T Y V +
Sbjct: 24343 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24402
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
++ T I L Y V AQN G S PL ++V I +P + T
Sbjct: 24403 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24462
Query: 1642 QVTPTSLSAQWTPP 1655
VT S W PP
Sbjct: 24463 AVTKDSCVVAWKPP 24476
Score = 31.6 bits (70), Expect = 9.4
Identities = 38/169 (22%), Positives = 66/169 (39%), Gaps = 21/169 (12%)
Query: 2027 SQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081
S ++SW+ +D + Y I TD+ + T+T T+TGL A Y
Sbjct: 23972 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 24031
Query: 2082 VEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESG 2138
+ A D + E VV + ++P+ + ++S +V +WE+ G
Sbjct: 24032 IIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDG 24086
Query: 2139 FKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2187
K + LG+ + + S W N K D+Q G ++ T
Sbjct: 24087 GK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24127
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 148 bits (373), Expect = 7e-35
Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
YG G+ +P+ S + P I E H I QW P+ + IS Y++
Sbjct: 22723 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22781
Query: 646 RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
R K S+ RW + +K L G Y+ ++ ++ G+ E +
Sbjct: 22782 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22831
Query: 704 TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
SN ++ ++P ++ V + T S ++W V Y L +E D
Sbjct: 22832 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 22888
Query: 763 PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
Q+ + + AT N +PDL G+KY V ++ G S ++ + P
Sbjct: 22889 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 22948
Query: 819 VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
++ DD ++ +R + P + S ++L +T S +L +
Sbjct: 22949 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23008
Query: 872 PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+Y+ Y +E ENQ +T +V +T G P P ++ EV+ VTI
Sbjct: 23009 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23060
Query: 927 WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
W P + V Y V+ + S+ T ++GL G YYF+V +
Sbjct: 23061 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23119
Query: 983 GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
+P + P L+ V+ T STV + W P +++TGY L
Sbjct: 23120 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23177
Query: 1035 RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
+ G R V P+V ++ + +L +Y + A KG E P+ T T+Q
Sbjct: 23178 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23236
Query: 1090 SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
+P + E I I P P F G + + E +
Sbjct: 23237 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23296
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
+ + T YT+++ I ++ PPT D +T+SW
Sbjct: 23297 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23356
Query: 1196 ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
E ++GY + + + E V +S+ F L+ G EY V
Sbjct: 23357 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23414
Query: 1248 YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
+ + +S I +P PP L+ ++ D M +TW PP +T ++V
Sbjct: 23415 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23474
Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
V+ + V + + T L G EY V+++ + P R + +D
Sbjct: 23475 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23534
Query: 1360 ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
P +D T S ++ W P + +TGY I + + P
Sbjct: 23535 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23594
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
TLT+L G EY ++A N G ++VP ++V P L
Sbjct: 23595 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23646
Query: 1471 PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
+ VR R+T G P+ ++T G + + + + +T V RGDS
Sbjct: 23647 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23705
Query: 1528 ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
K + I R I P+ ++ D+Q S+ V W P + + +
Sbjct: 23706 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23764
Query: 1571 GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
GY + PK ++ G T + ++GL+ VEY V A+N G S+PL
Sbjct: 23765 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23821
Query: 1629 VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
T P + + VT +S+S W+ P ++TGY + ++
Sbjct: 23822 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 23881
Query: 1677 EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
++ V+GL+ +Y+ + A D + TS ++ VV + S P
Sbjct: 23882 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 23941
Query: 1732 VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
+ ++ ++T+ W + I G+ V+ +G + +++ K + + +TI GL
Sbjct: 23942 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 24000
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
T+Y+ ++ N+ S P
Sbjct: 24001 ATEYEFRVFAENETGLSRP 24019
Score = 140 bits (353), Expect = 1e-32
Identities = 320/1467 (21%), Positives = 549/1467 (37%), Gaps = 222/1467 (15%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13293 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13349
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13350 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13394
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13395 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13451
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13452 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13511
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13512 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13569 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13621
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
+ + TF VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13622 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13680
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740
Query: 1054 RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
L EY ++AI G P V L P PP EV T ++ +
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13796
Query: 1107 WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
WT P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13797 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13856
Query: 1159 GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
AP + + T + PT L ++A DT VL S
Sbjct: 13857 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 13915
Query: 1195 WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
W ++ DIT +IT+TPT+ +++ D T +P + V V
Sbjct: 13916 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 13968
Query: 1251 KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
K T++ PP + +N+ + +TW PP D + + Y K E
Sbjct: 13969 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14018
Query: 1311 VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
++ D V T L+ G EY+ VS+V + P++ +D P
Sbjct: 14019 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14078
Query: 1362 TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
+ S++T N+ TV W P + ITGY + + R + P S +T
Sbjct: 14079 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14138
Query: 1418 LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G+ Y + A N P +L+ + P + V T S ++W
Sbjct: 14139 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14198
Query: 1471 P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
P + + Y + + + G + +++ T + T + L+ Y + A+ G
Sbjct: 14199 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14258
Query: 1526 -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
PA + I R + + ++++ T V +S++ VT T N
Sbjct: 14259 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14318
Query: 1582 PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
+ + + I T ++V+++ +NP+G+ V V P P +
Sbjct: 14319 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14376
Query: 1638 LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
L+ T +T S++ W P + ++T Y V +++ K + A + V+
Sbjct: 14377 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 14432
Query: 1691 GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
GL +Y V A + P + V E SPP + D T++T++++W
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 14492
Query: 1745 RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
ITG+ ++A + Q T+K + L G +Y + +N RS+
Sbjct: 14493 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 14550
Query: 1804 -----PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 1858
PV++ T + +LR + +Q G IK E P V+
Sbjct: 14551 PRESRPVIVKEQTML-PELDLRGI----------YQKLVIAKAGDNIKVEIP------VL 14593
Query: 1859 PRPRPGVT---------EATITGLEPGTEYTIYVI--ALKNNQKSEPLIGRKKTDELPQL 1907
RP+P VT + E TI I ++++ PL R E+ +
Sbjct: 14594 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 14653
Query: 1908 VTLPHPNLHGPEILDVPSTVQKTPFVT 1934
+T+ ++ GP + + FVT
Sbjct: 14654 ITIQVHDIPGPPTGPIKFDEVSSDFVT 14680
Score = 129 bits (323), Expect = 4e-29
Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7279 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7337
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7384
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7385 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7444
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7445 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7504
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7562
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7563 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7622
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7623 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7681
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7682 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7741
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7742 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7801
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7802 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7860
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 7861 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 7914
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 7915 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 7973
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ +I P D++ ++I + ++TW PP T L + + +
Sbjct: 7974 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8033
Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
+N + T +L+P EY V +V Y + ++ + K D P ++ +
Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8093
Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
TA + T+ W P + I GY I E R E VP + T L G
Sbjct: 8094 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8151
Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
EY + A N S T + P D +V+ T + I+ DA Y
Sbjct: 8152 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8211
Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
IT+ GE P Q ++ SK + +
Sbjct: 8212 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8271
Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
+ + +Y + D + P +++ P D++ S+ KW P
Sbjct: 8272 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8331
Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + Y + K P T+ + ++ L EY+ V A+N G P
Sbjct: 8332 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8391
Query: 1624 LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
V + AP VT S+ +W P + GY + T
Sbjct: 8392 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8451
Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
+ ++ V GL+ Y V A + P T + +SPP
Sbjct: 8452 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 8511
Query: 1731 RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
RVTD + TTI + W I G+ VD + T K VR YT+ ++
Sbjct: 8512 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 8571
Query: 1786 GTDYKIYLYTLNDNARSSP 1804
G DYK+ + +N P
Sbjct: 8572 GADYKLRVSAVNAAGEGPP 8590
Score = 128 bits (321), Expect = 7e-29
Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 6939 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 6994
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 6995 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7054
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 7055 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7114
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 7115 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7173
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7228
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 7229 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7281
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 7282 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7338
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 7339 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7397
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 7398 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7456
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
V K K + P I D I P PP PT ++G ++R+ W P
Sbjct: 7457 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 7513
Query: 1292 -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
+ ++++ +E V P+ +L L+ G EY V +V + E
Sbjct: 7514 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 7572
Query: 1347 --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
S P+ R+K S P ++ +IT N+ + W P + IT Y + G
Sbjct: 7573 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7632
Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
D T+T LT G+ YV + A N E +L T P
Sbjct: 7633 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7691
Query: 1453 DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
L VV T + + W+ P ++ Y I E G V+ G ++ +
Sbjct: 7692 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7751
Query: 1509 KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
G + V A G G ++ +SI T P + VTD I++ W P
Sbjct: 7752 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 7811
Query: 1565 ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
SP+ GY V P + + + + EG+ P EYV+ V A N G
Sbjct: 7812 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 7871
Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
S+P + + + D K T T + + G ++ + + P+ ++
Sbjct: 7872 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 7923
Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
D V S + +S + L+ + R G+ T TLEN
Sbjct: 7924 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982
Query: 1724 VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
P + + +D T+++ ++W I + ++ A +T I + S+T
Sbjct: 7983 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8042
Query: 1780 ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
+ L P +Y + +N ++ + D D P ++ T ++ ++
Sbjct: 8043 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8102
Query: 1833 WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
W+PP ++I GYII+ G + + T GLE G EY V A
Sbjct: 8103 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8162
Query: 1889 NQKSEP 1894
SEP
Sbjct: 8163 AGISEP 8168
Score = 127 bits (318), Expect = 2e-28
Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
+ ++++ V W D G ++ + E+ + + + +AT + L+ G
Sbjct: 11808 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11866
Query: 784 RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
+YI V ++ G E +++ ++ P P P V +V + V W+ P+
Sbjct: 11867 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 11926
Query: 836 -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
ITGY + +N +PE V +L P +Y + A E P
Sbjct: 11927 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 11984
Query: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
+ + + P + + V+ T +T+ W P + + GY V++ P
Sbjct: 11985 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12044
Query: 947 --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
P E +R + R F VT L Y F+V A V GR ++ A + ++
Sbjct: 12045 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12103
Query: 998 DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
P + V+VR P ++T ++ + + R+GQ +
Sbjct: 12104 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12162
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
+ P + +Y+++LV G + V T P S + ++VT+T+ +
Sbjct: 12163 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12220
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
+W P G G + + RE + S V V+ L PG EY + +
Sbjct: 12221 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12277
Query: 1156 LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
+ + G D P PLS PP L + T++W R I GY
Sbjct: 12278 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12336
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
IT+ Q + E S L G +Y V V +E+ + +
Sbjct: 12337 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12395
Query: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
+PP + P+ + + I+ + + K E++V + L+
Sbjct: 12396 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12449
Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
+ +D++ +L + S E T + + +D+P D SDI A
Sbjct: 12450 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12509
Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
++ ++ W P G I ++ R D V ++ S + L PG EY+
Sbjct: 12510 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12568
Query: 1428 IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
+ A N G E SP ++ Q V P++ V + ++WD P
Sbjct: 12569 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12618
Query: 1482 YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
++ G SP+ + + + + + +GL G++Y+ +YA+ G
Sbjct: 12619 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12676
Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
SP S + R +D P + +V DV +++S+ W S + GY V G
Sbjct: 12677 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12736
Query: 1582 PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
+ TA Q E T GL+ +Y + + + +TAV P P+D
Sbjct: 12737 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 12785
Query: 1638 LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
P ++ A+ PP + L+ + +T K T PM ++ D +
Sbjct: 12786 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 12838
Query: 1687 V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
+ G+ +A + + L KD T+T+ + G + L+ PP
Sbjct: 12839 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 12898
Query: 1731 RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
++ +SW E IT + VD + Q + + S ++ L G
Sbjct: 12899 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 12958
Query: 1787 TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
+Y+ + N PV + A D P T + + VSW+PP
Sbjct: 12959 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 13018
Query: 1838 -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
+ ITGY++ EK + R + E T+ TGL+ GTEY V A+ +P
Sbjct: 13019 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 13076
Score = 125 bits (314), Expect = 5e-28
Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
N+ + W P S I+ Y + R K S+ RW A P + GL+ G YE
Sbjct: 14089 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14147
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
++ + + G + S++V + + P ++ VT+ T S ++
Sbjct: 14148 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14195
Query: 740 W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
W ++G+ VE++ + GDE D TA + +PDL KY +
Sbjct: 14196 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14253
Query: 793 ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
I++ G + ++ + + PD +D ++VVR R PI G +P
Sbjct: 14254 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14310
Query: 849 VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
V + +NL AN ++ + + I ++ V+ E +S V
Sbjct: 14311 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14364
Query: 908 ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
P P +L+ ++T VT+ W P S +T Y V+
Sbjct: 14365 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14424
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
+ T+ +VTGLS G Y+F+V A + +P + K P +L ++ T ST
Sbjct: 14425 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14483
Query: 1013 VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
V + W P+ ++ITGY + R+G + ++ + +RNL EYT ++
Sbjct: 14484 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14541
Query: 1068 AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
A+ S ++ + +P + +VI P P +
Sbjct: 14542 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14601
Query: 1115 FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+K G + Q E T+ S + ++ Y + E I +V
Sbjct: 14602 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14661
Query: 1174 LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PPT + +T SW E I+ Y + T+ L V
Sbjct: 14662 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14721
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
T L+ GLEY V I+ I A VP PP + T + D+M
Sbjct: 14722 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14779
Query: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
++W P S + L + K + ++S + N + L G Y V +
Sbjct: 14780 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 14839
Query: 1342 YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
+S P + + +D P +IT ++ T+ W P T IT Y +
Sbjct: 14840 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 14899
Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
+ + N T++ LT Y ++A N I S SD
Sbjct: 14900 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 14955
Query: 1454 LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
+ V A + + + + +R+ +G P E++ G + T
Sbjct: 14956 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15015
Query: 1512 VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
D++ + A T +P N + +D+P + VT+V
Sbjct: 15016 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 15074
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
+ W P + + Y V + T + T++ + L EY+ V
Sbjct: 15075 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 15133
Query: 1614 AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
A N G +PL V + P + + T +T S+ W P+ ++ Y
Sbjct: 15134 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 15193
Query: 1664 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
V K +K VSGL +YE + A S P+
Sbjct: 15194 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15253
Query: 1719 TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
T+ PP RV D + ++I+I+W ITG+ V+ A+P + I + P
Sbjct: 15254 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 15310
Query: 1774 DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
SYTITGL +YKI +Y +N P ++
Sbjct: 15311 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15348
Score = 123 bits (308), Expect = 2e-27
Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 12987
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 12988 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13047
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13048 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13107
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13108 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13167
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13168 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13226
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13287 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13344
Query: 1136 G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13345 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13401
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13402 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456
Query: 1246 SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
V ++ E P T++ V P DL+ PD + + P
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13513
Query: 1290 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
PS+ S K E+ +A + +++ V T L+ +Y +++ +V
Sbjct: 13514 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13564
Query: 1343 EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I +
Sbjct: 13565 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13621
Query: 1397 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
+ + + + +T L G EY + A N G + P++ V D
Sbjct: 13622 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13681
Query: 1451 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
P +V S+ ++W P T + Y + + E + P ++
Sbjct: 13682 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13741
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
GL G++Y V A+ G S + ID P + +V ++ NS+++ W
Sbjct: 13742 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13801
Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
+TGY V K + T+ L +Y + A+N +G
Sbjct: 13802 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13861
Query: 1623 PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
++ T I APT + L+ + + L + P K+ K
Sbjct: 13862 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 13919
Query: 1677 ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
+I P SS + + AT+ + Y + T ++ VT L+
Sbjct: 13920 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 13976
Query: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
PP +++ + T++W E + +T + + D++S +
Sbjct: 13977 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 14036
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
T L G +Y + +N + PV + +D P T N+ VSW+
Sbjct: 14037 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 14096
Query: 1835 PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
P + ITGY ++ + S + +TGL+ G+ Y V A
Sbjct: 14097 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 14151
Score = 122 bits (307), Expect = 3e-27
Identities = 286/1294 (22%), Positives = 482/1294 (37%), Gaps = 173/1294 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20652
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20653 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20708
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20709 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20765
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20766 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20816
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 20817 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 20875
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 20876 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 20935
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 20936 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 20991
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 20992 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21051
Query: 1259 ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
I + + P DL T+R+ P PSI ++L P+K
Sbjct: 21052 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21108
Query: 1307 NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
E V S ++N + L+ G +Y V + + + P+ P
Sbjct: 21109 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21164
Query: 1363 G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
G I F +I A+S + W P IT Y I E + +R + + N
Sbjct: 21165 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21223
Query: 1418 LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
L EY + A N S L+ Q + P + T + ++WDAP
Sbjct: 21224 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21283
Query: 1472 AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
V + + E + T P S +GL G+DY VYA G S
Sbjct: 21284 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21343
Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
S + +D P DV +I++KW P S + GY + N
Sbjct: 21344 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21403
Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
+ + + T+ GL P Y + A+N P +S ++ T +P +
Sbjct: 21404 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 21462
Query: 1638 ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
+K + Q P ++T ++ V +++ EI S+S+
Sbjct: 21463 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 21519
Query: 1688 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
V AT+ VY ++ S A+ + +P + R T+ T +T+ W
Sbjct: 21520 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21576
Query: 1745 RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
IT + ++ + K + +SYT L G +Y+ + +N
Sbjct: 21577 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 21636
Query: 1799 ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
S PVV T DAP T NS+ ++W P + I YI+ + EK
Sbjct: 21637 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 21696
Query: 1850 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT 1909
+ +V+ + T +TGL G EY +V+A +N P G + + + V
Sbjct: 21697 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVN 21755
Query: 1910 LPHPNLHGPEILDVPSTVQKTPFV--THPGYDTG 1941
P P P ++ V T + T + + P +D G
Sbjct: 21756 PPGP----PTVVKVTDTSKTTVSLEWSKPVFDGG 21785
Score = 116 bits (291), Expect = 2e-25
Identities = 282/1346 (20%), Positives = 481/1346 (35%), Gaps = 213/1346 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17656
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17657 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17703
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17704 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17759
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17760 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17819
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 17878
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 17931
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 17932 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 17990
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18108
Query: 1093 PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ + + P G + + T +E
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18162
Query: 1149 YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
+T+ L + Q + ++ + S P+ N L+ ++
Sbjct: 18163 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18222
Query: 1193 VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
+ E DI G I + + G LEE + T + G +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 1243 YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Y + + V K S+PI+ ++ PP L+ T + + + W PP N
Sbjct: 18282 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18340
Query: 1302 YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
+ ++ +S A+ +T LLPG EY+ V +V + PL T +
Sbjct: 18341 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400
Query: 1360 ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
P+ + S IT +S V W P I GY + + + ++ +
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460
Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
+ +T LT G Y + A N G P + + P + +V + +
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18520
Query: 1463 SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
S+ ++W P G +PV+ + V ++ A T+
Sbjct: 18521 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18568
Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
+ LK +Y + A+ G ++ P S+ + I+ P D++ V L +
Sbjct: 18569 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18624
Query: 1566 SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
S+ + R+ T K P P K + D Q E+T ++ V ++
Sbjct: 18625 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18681
Query: 1613 YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
+N SG V V P AP +L +V S++ W PP ++T Y +
Sbjct: 18682 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 18738
Query: 1668 PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
K +T + + + + L Y V A + PA+ V E
Sbjct: 18739 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 18798
Query: 1724 VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
PP R + D T T TI W K E+ ITG+ V+ + G +
Sbjct: 18799 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 18856
Query: 1779 TITGLQPGTDYKIYLYTLNDNARSSP 1804
TI+GL G +Y + +N+ RS P
Sbjct: 18857 TISGLTAGEEYVFRVAAVNEKGRSDP 18882
Score = 116 bits (291), Expect = 2e-25
Identities = 149/690 (21%), Positives = 263/690 (38%), Gaps = 70/690 (10%)
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
PP ++ I ++ ++W PP L+ ++V + +S S + +
Sbjct: 23337 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 23395
Query: 1325 LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
T L G EYV V++ Y Q E R + P + D++ + T+
Sbjct: 23396 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 23454
Query: 1378 WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
W P + +TGY + R ++VP + T LT G EY + A+N
Sbjct: 23455 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23514
Query: 1434 R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
R P++ P++ V T TS+ ++W P V Y I
Sbjct: 23515 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 23574
Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
+ + + T P T++ L G +Y V A G + P ++ +
Sbjct: 23575 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23634
Query: 1543 DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
+ P ++ + I V+ + + P+ G + + K G +K +T
Sbjct: 23635 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 23693
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
E+ I+ + +N G+ ++ V P + L++ + S+ W
Sbjct: 23694 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23753
Query: 1654 PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
PP + GY + R PK I+ +S+VV GL +Y V A
Sbjct: 23754 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 23810
Query: 1708 TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
S+P ++ VT ++PP V D T++++++SW R K + +TG+ ++
Sbjct: 23811 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 23870
Query: 1758 AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
+ ++ K + + YT+TGL P +Y+ + ND + S PVV D
Sbjct: 23871 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 23929
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
P L L+ + +S+ + W+ P I GY ++Y + G + + R
Sbjct: 23930 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 23989
Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ TI GL TEY V A S P
Sbjct: 23990 DKQFTIGGLLEATEYEFRVFAENETGLSRP 24019
Score = 113 bits (283), Expect = 2e-24
Identities = 299/1397 (21%), Positives = 486/1397 (34%), Gaps = 195/1397 (13%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 18275 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18329
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 18330 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18387
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 18388 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18446
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 18447 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 18500
Query: 905 DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 18501 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18560
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
L G+ VT L Y F++ A++ +P T AQ+ +
Sbjct: 18561 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18609
Query: 997 --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 18610 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 18666
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 18667 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18726
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 18727 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18842
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
++ ++ +V + T L+ G EY V V + S P + +I + P
Sbjct: 18843 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 18899
Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
+L F P V + V + + V LSI
Sbjct: 18900 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 18959
Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
+ V GT + +S + + G P ID +++ +S T+ W
Sbjct: 18960 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 19011
Query: 1379 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
P I+ Y I E S +R SI + LT G+EY + A N
Sbjct: 19012 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19070
Query: 1434 -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
E S ++ + P +VV AT +++L++W P V Y + Y E
Sbjct: 19071 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19130
Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
+ + + + +SGL G+ Y VYA + G G S +P+ R
Sbjct: 19131 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 19188
Query: 1543 DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
D P Q +VT++ S+S+KW + +TGY V K +T
Sbjct: 19189 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19248
Query: 1599 IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
+ L Y V+A+N PS + P +V+ V D+KF V +
Sbjct: 19249 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 19307
Query: 1651 QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
+ N + G + V K G E ++ D+ +++ + V L
Sbjct: 19308 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19367
Query: 1706 KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
K+ +R L+ PP + T ++SW E G +D V
Sbjct: 19368 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 19426
Query: 1763 GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
+ + TI + + S +T L G +Y + +N P+ +D T
Sbjct: 19427 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19486
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
P++L + T S+ + W P + I+GYII+ + S V +
Sbjct: 19487 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19546
Query: 1870 ITGLEPGTEYTIYVIA-----LKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 1924
TGL G EY V A L ++ PLI + V LP P P+I+D
Sbjct: 19547 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP------VFLPSPP-SKPKIVDSG 19599
Query: 1925 STVQKTPFVTHPGYDTG 1941
T +V P +D G
Sbjct: 19600 KTTITIAWV-KPLFDGG 19615
Score = 112 bits (281), Expect = 3e-24
Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)
Query: 606 PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
P GPVE+ + + W P S I YIL R + + W +
Sbjct: 13976 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14030
Query: 663 LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
+ L G Y ++ ++ YG E PV S V P
Sbjct: 14031 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14077
Query: 723 ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
V+ +T ++ VSW D ++G+ VE + + + P + +
Sbjct: 14078 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14137
Query: 779 DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
L G Y V + G +L P P +P V S + W
Sbjct: 14138 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14197
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
+P ITGY +V V + + TA +T + DLQ +YN I A+ +
Sbjct: 14198 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14256
Query: 886 NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
P VI E + +L+ V ++I P V
Sbjct: 14257 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14316
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
N+ ++ + NT + + P Y K K LD P
Sbjct: 14317 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14373
Query: 1001 -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
NL+ + T +V + W P G R+T + + + + + + +K Y +
Sbjct: 14374 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14432
Query: 1055 NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
L EY ++A G E + T + S N ++T++T+ + W P P
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14491
Query: 1112 R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
+ G+ + + +G + +T+ G VV LT G EY + + + R
Sbjct: 14492 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14550
Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
P++ K T L L L V+ + + + P + + T T G Q
Sbjct: 14551 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14607
Query: 1218 G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
+ V ++ T N++ + + Y + + D I V PP
Sbjct: 14608 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14667
Query: 1272 DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
++F + D + +W PP + + ++N++V + V EL+ + T L
Sbjct: 14668 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14726
Query: 1329 LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
G EY V + V S + + P G + +T +S T+ W P
Sbjct: 14727 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14786
Query: 1383 AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
+ I GY + + + N + LT G Y ++A N
Sbjct: 14787 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14846
Query: 1433 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
+ P+L P L + T T + W P T + +Y + P
Sbjct: 14847 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 14903
Query: 1492 QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
+ + T+SGL Y V A G SP S +I R +++ P
Sbjct: 14904 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 14963
Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
+D I +R+ P PT + G + E+ I
Sbjct: 14964 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15016
Query: 1601 GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
+ ++ A NP G ++ + V P P + L T+VT
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15076
Query: 1650 AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
W PP ++ Y V+ K +T + N+A + + + V+ L+ +Y
Sbjct: 15077 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 15133
Query: 1699 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
V+ Y + + L S P V PP+ VT T+ ++ + W ++
Sbjct: 15134 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15192
Query: 1759 VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
+ QR IK + ++ Y ++GL G +Y+ + N S+P
Sbjct: 15193 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 15252
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
D P N R L T+ +S+ ++W P + ITGY+++ P ++V P
Sbjct: 15253 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 15312
Query: 1863 P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
T TITGL EY I + A+ + EP +
Sbjct: 15313 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15347
Score = 110 bits (275), Expect = 2e-23
Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
N V P P+ S E+T V+SW D G ++ + E+ + + + +
Sbjct: 10410 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 10463
Query: 769 PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
P T+ T+ + LL G+ YI N+Y IS+ + + + PDAP P V
Sbjct: 10464 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 10523
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
+V S +V W++P PIT Y + ++ + + DL G
Sbjct: 10524 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 10583
Query: 875 QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
QY + A E P + P + + ++ T V + W PP
Sbjct: 10584 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 10643
Query: 932 -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
S + GY V+ V + P S T +VTGL G TY F+V AV+ ES P
Sbjct: 10644 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 10703
Query: 989 LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
+ +L+ P + N + R A I G ++T R P
Sbjct: 10704 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 10763
Query: 1040 RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
+ +V P SK +RN SL + V +PG PP + E
Sbjct: 10764 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 10820
Query: 1098 VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
V+E + +TW G + + R + +P TS S L G
Sbjct: 10821 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 10880
Query: 1148 EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
+Y++ +V + Q P V K + PL PP +LH + D +++ W +
Sbjct: 10881 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 10937
Query: 1197 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
R ITGY + Q + V + + C L G Y V ++
Sbjct: 10938 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 10992
Query: 1257 VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
+ + DT IP VPP +L I T+R + P P+ T
Sbjct: 10993 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 11049
Query: 1301 RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
S +K +E + + S + L T EY ++VS+ + T LD
Sbjct: 11050 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 11105
Query: 1360 ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
PTG I+ D+T T+ W P+ I + E R V S +S T
Sbjct: 11106 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11165
Query: 1415 --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
+ +L G EYV + A N + +P + + + P V T + +
Sbjct: 11166 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11225
Query: 1467 SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
SW P + YY TG V + + K T GL G Y V+A
Sbjct: 11226 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 11283
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S S I I P ++ D + + W SP+ GY V
Sbjct: 11284 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 11343
Query: 1575 TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
PG + D Q + GL EY + A N GE +P L ++
Sbjct: 11344 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 11400
Query: 1629 VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
+ I P +++ VT + +++ RV+ P+ K G + K +
Sbjct: 11401 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 11458
Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
+L D V + + A + + Y + +S AQG +V L+ P + +VT+ T
Sbjct: 11459 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11517
Query: 1737 ETTITISWRTKTET----ITGFQVD 1757
+ TISW + IT F V+
Sbjct: 11518 KENCTISWENPLDNGGSEITNFIVE 11542
Score = 110 bits (274), Expect = 2e-23
Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
+T++T S +++W D Y + D + L ST N L+P +
Sbjct: 7295 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 7354
Query: 785 KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
+YI N+Y + E + S I + Q P P + ++ + W P
Sbjct: 7355 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7414
Query: 836 APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
+PITGY + P + +P + + L +Y + A + +S
Sbjct: 7415 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7474
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
T ++ ++ P P+ +D V V + WT PE + + Y ++++
Sbjct: 7475 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7529
Query: 946 LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
+ +P +++ + GL G Y F+V AV+ ES+P L ++
Sbjct: 7530 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7586
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
P L+ +N T +T ++WT P + IT Y + RR + + +K
Sbjct: 7587 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7646
Query: 1053 LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
+ L S Y + A ++S A FTT PG PPY V + T
Sbjct: 7647 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 7701
Query: 1103 -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
+ + W P G + LG R + G+ + V+ + G E
Sbjct: 7702 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 7757
Query: 1150 VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
+ ++ + + + + +P SPP +LH+ D G + ++W E++
Sbjct: 7758 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 7814
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I GY + P ++ + D + + P EY + V V S P
Sbjct: 7815 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7874
Query: 1259 --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
IS+ ++ P P DL +I P R P S V+ S
Sbjct: 7875 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 7934
Query: 1305 ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
+KN+ A L + S A + L N L ++V +
Sbjct: 7935 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 7980
Query: 1356 TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
GL P I SDIT +S + W P G I H+ R +P ++
Sbjct: 7981 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 8038
Query: 1411 NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S T+ +L P EY + A+N G E ++P++ D P D+EV T +
Sbjct: 8039 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 8098
Query: 1464 LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
+ I+W P + Y +I GE E VP T T GL+ G +Y
Sbjct: 8099 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 8155
Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
V A G S S ID P + T ++ D SIS +
Sbjct: 8156 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 8215
Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
W+ + + + K P + G Q E
Sbjct: 8216 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8271
Query: 1600 -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
+ L+P + + +N G ++ P + + T P + F + TS+ +W PP
Sbjct: 8272 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 8330
Query: 1656 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
++ Y + K K PDS +VV+ + KY V+ Y +
Sbjct: 8331 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 8380
Query: 1708 TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
+R G V L P P + V D T ++ + W + I G+
Sbjct: 8381 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 8440
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
++ N + + +++ +++ + GL G Y + N + SP D T
Sbjct: 8441 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 8498
Query: 1812 AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
A D P R T+ ++ + W+PP I GY + + G+
Sbjct: 8499 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8558
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V + T+ + G +Y + V A+ + P
Sbjct: 8559 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 8590
Score = 110 bits (274), Expect = 2e-23
Identities = 298/1381 (21%), Positives = 508/1381 (36%), Gaps = 185/1381 (13%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15066 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15183
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15184 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15242
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15299
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15300 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15359
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15360 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15410
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15411 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15470
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15471 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15527
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15528 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15585
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15586 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15642
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
D +IP FT + + ++V P P++ V P+K
Sbjct: 15643 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15696
Query: 1314 LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
++ ++N +LT E YVV + +S E E+ + K G PTG +
Sbjct: 15697 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15754
Query: 1368 DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
++TA+S T+ W P+ ++I Y + + + + +R +I L G E
Sbjct: 15755 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15813
Query: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
Y I A N +S L + TV+ P + TP S+ + W+ P
Sbjct: 15814 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15872
Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
V Y + E V+ P ++ +GL+ GV+Y V A G S
Sbjct: 15873 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 15932
Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
R D P + + V NS++++W S +TGY V K
Sbjct: 15933 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 15992
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
T + GL Y V A+N +G S+P T T D S
Sbjct: 15993 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 16047
Query: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
+ ++ V G +V P+ I +++ + + AT V
Sbjct: 16048 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 16107
Query: 1702 ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
+ K+ R V L+ PP ++ T T++W+ +
Sbjct: 16108 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 16167
Query: 1751 ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
++ + +T + + +V+ S +T L G +Y + Y + +
Sbjct: 16168 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 16227
Query: 1802 SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
S PVV + DAP T +S++V W+ P + I GY++ K +K G
Sbjct: 16228 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 16287
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 1915
R G +TGL +Y V A SEP + PN
Sbjct: 16288 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPN- 16345
Query: 1916 HGPEILDVPSTVQKTPFV--THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPP 1973
P+++D+ + + F+ + P YD G IQ SVG+ + TPP
Sbjct: 16346 -NPKVIDI---TRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE--------WTMCTPP 16393
Query: 1974 T 1974
T
Sbjct: 16394 T 16394
Score = 109 bits (273), Expect = 3e-23
Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6548 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6607
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6608 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6666
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6667 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6726
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6727 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6786
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6787 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6844
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 6845 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 6903
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 6904 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 6963
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 6964 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7018
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
+TGY + + + + + V T +L G EY V E
Sbjct: 7019 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076
Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
+ + + + P PP ++++ + +++ +TW PP + + ++V P +++
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7136
Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
VA ++ + +T L G Y V ++ Q S P R ++ +D +
Sbjct: 7137 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7190
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
V +A G +I P +G+P + D + IT+ N+
Sbjct: 7191 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7247
Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
+ V+IV + +I G+ + V +V P ++ T S L++W
Sbjct: 7248 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7307
Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
+ P + Y + T +S V++ +K L P +Y V
Sbjct: 7308 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7360
Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
A G P + PI+ Y+ + P++++ +D+ +++++ W SP+TGY
Sbjct: 7361 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7420
Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
V + + T ++GL +Y V A+N +G +P T I
Sbjct: 7421 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7480
Query: 1633 PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
P D + P TS+ WT P ++ Y + + KTG + + +A
Sbjct: 7481 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 7537
Query: 1682 P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
++ ++ GLM +Y V A+ S P++ V E + SPPR V +
Sbjct: 7538 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7597
Query: 1735 ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
T+ T + W + IT + V+ V G + T+K T+T L G+
Sbjct: 7598 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 7655
Query: 1789 YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
Y + N +S S + D T P L + T + + W+PP+
Sbjct: 7656 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 7711
Score = 109 bits (273), Expect = 3e-23
Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)
Query: 692 VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
VTRFD S +T +G T F SP + ++ E+ S +SW
Sbjct: 18671 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18726
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ ++ + VE E Y + + T T+ I +L G Y V +E G
Sbjct: 18727 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783
Query: 799 QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
L T++ PP P T+ V + ++W +P++ ITGY V +
Sbjct: 18784 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 18840
Query: 851 GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
GS + T+S L G +Y + AV E S P VI ++ P
Sbjct: 18841 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 18898
Query: 905 DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
+V P V+ + +K+ + + A +R D GQ L ++ +
Sbjct: 18899 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 18947
Query: 960 TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
+ VT LS V Y + S G + P+T + P ++ + ++
Sbjct: 18948 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19007
Query: 1014 LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
+ W PP QI+ Y V + V +V++ ++ L SEY +
Sbjct: 19008 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19065
Query: 1068 AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
A ES + PG P T++T+++TW IG+
Sbjct: 19066 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19125
Query: 1117 LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
L + +A + + +D+ + VSGL G+ Y VY + G+ +
Sbjct: 19126 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19184
Query: 1171 VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
P PP TN+ ++ + D G + ER PD G + TN
Sbjct: 19185 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 19242
Query: 1216 QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
Q+ + DQ + D++S E + VKDD E V D
Sbjct: 19243 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 19301
Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
I+ + G ++WA I++ E+ A I +DN
Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 19347
Query: 1323 VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
+LT +YV+++ +V + + K G P G ++ + +TA ++
Sbjct: 19348 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 19405
Query: 1377 HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
W P+ A I Y + + H + E + S +T L G EY+ + +
Sbjct: 19406 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 19463
Query: 1432 NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
N E + TV P LE+ + T S+ + W P + Y I
Sbjct: 19464 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19523
Query: 1482 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
E V+ P +GL+ G +Y VYA G S P+ + P+ I
Sbjct: 19524 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 19582
Query: 1541 EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
+ PS+ ++ D +I++ W+ +P+TGY V K+ KT
Sbjct: 19583 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 19641
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
TE TI GL EYV V + N PS S P + P ++++ T +
Sbjct: 19642 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 19701
Query: 1645 PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
S T P +R R P +T + + S ++ + +
Sbjct: 19702 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 19755
Query: 1696 TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
KY +++ ++ L++ VV L+ PP V D T+ + +SW +
Sbjct: 19756 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 19812
Query: 1752 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
+ ++ A+ + + T + SY +T LQ G Y + N+ P
Sbjct: 19813 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 19872
Query: 1812 AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
I P L + + +S+ ++W P +RI Y+++ + G + V
Sbjct: 19873 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 19930
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
T ++GL +EY V A S+P
Sbjct: 19931 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 19961
Score = 105 bits (262), Expect = 5e-22
Identities = 346/1650 (20%), Positives = 609/1650 (36%), Gaps = 262/1650 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8718 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8775
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8776 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8822
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 8823 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 8883 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 8938
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 8939 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 8999 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9055
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9056 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9115
Query: 1011 STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9116 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9171
Query: 1057 QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
+Y +AI ++ S PG P + T+++I + W P
Sbjct: 9172 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9231
Query: 1111 PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
K G P +G E E T+D + VV L +Y + ++ +
Sbjct: 9232 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9287
Query: 1157 RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
+ G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9288 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9347
Query: 1214 --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
+G+ ++++ VH D T +N S + +Y+++ K +++
Sbjct: 9348 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9406
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
++ PP DL+ ++I + R++W P D + + Y K D A ++
Sbjct: 9407 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9465
Query: 1318 P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
P V+ +LL +Y V + P+ Q+T D P +
Sbjct: 9466 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9525
Query: 1369 ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
IT N+ + W P+ + +T Y + +G +E R + R+ T+ +L
Sbjct: 9526 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9585
Query: 1420 PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
G EY + A+N G + +G D+ +EV T +++
Sbjct: 9586 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9645
Query: 1470 APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
P T+ +++ + PV T V T I + T+ AV
Sbjct: 9646 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9705
Query: 1525 GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
G +SK + +N P ++ V + +++ W P S +T Y +
Sbjct: 9706 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9762
Query: 1580 NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
N KT ++ P + TI L EYV + AQN G +PL T +
Sbjct: 9763 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818
Query: 1632 IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
+P AP + VT S++ W P +TGY + + K+ T K +N P +
Sbjct: 9819 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 9876
Query: 1686 -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
S V+GL+ + Y+ VYA+ +L S PA T + ++PP +V
Sbjct: 9877 MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 9932
Query: 1733 TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
TD T+++ + W + +TG+ V+ G+ ++ +VR +TGL+ G
Sbjct: 9933 TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 9991
Query: 1787 TDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1842
YK + +N P VI+ + +P +L+ A+ + ++V RI
Sbjct: 9992 AFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGVIRIIA 10049
Query: 1843 YIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE----PLI 1896
Y+ G PP V R EATI T + +KN Q+S L+
Sbjct: 10050 YV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQGVYSLL 10099
Query: 1897 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL----PGTSGQ 1952
+ + E + + + ++LDVP V TPF+ H T +L P G
Sbjct: 10100 AKNEAGERKKTIIV--------DVLDVPGPV-GTPFLAH--NLTNESCKLTWFSPEDDGG 10148
Query: 1953 QPSVGQQMIFEEHGFRRTTPPTTATPIRH--------RPRPYPPNVGEEIQIGHIPREDV 2004
P + +I + RR P T T R + + Y + E IG P +
Sbjct: 10149 SP-ITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 10207
Query: 2005 DYHLYPHGPGLNPNASTGQEALSQT----TISWAP--FQDTSE---YIISCHPVGTDEEP 2055
L P P E T T++W P + SE Y++ +GT++
Sbjct: 10208 SEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFH 10267
Query: 2056 LQFRVPGTSTSATLTGLTRGATYNIIVEAL 2085
S T+ GL G TY V A+
Sbjct: 10268 KVTNDNLLSRKYTVKGLKEGDTYEYRVSAV 10297
Score = 105 bits (261), Expect = 7e-22
Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
++A +SW D Y + + E + ++ + S + IP LL G +Y+
Sbjct: 9732 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9791
Query: 788 V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
N Y I E + + + + P AP PTV V S+ V W P+ +P+
Sbjct: 9792 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9851
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
TGY + + +N + ++TL + L G Y +YA+ P
Sbjct: 9852 TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 9909
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
+ + P P + + T + W+PP S VTGY V+
Sbjct: 9910 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 9969
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
+ R T VTGL G Y F+V AV+ E K +L
Sbjct: 9970 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10029
Query: 998 DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
DA + V + V PP +T + R P++ + + S
Sbjct: 10030 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10083
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
++N Q + + SL+A E K V PG P+ +T + +TW
Sbjct: 10084 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10143
Query: 1110 -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
+P + + R S + P T + V GL G Y + I
Sbjct: 10144 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10203
Query: 1159 -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
+ +A ++ + +T P +L ++ +T++W + +I Y + +
Sbjct: 10204 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10262
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
++ + + + T L G EY VS + K + PI T +
Sbjct: 10263 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10319
Query: 1269 PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
PPT +R T R + P P + S K+E DV E +
Sbjct: 10320 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10370
Query: 1315 SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
+P+ A+ G VV +S + + + G P G + F ++T
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 10428
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
+ + W P G +I ++ ++ +P ++ + ++ L G +Y+
Sbjct: 10429 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 10487
Query: 1427 SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
I A N S L+ V D P V T S L++W+ P
Sbjct: 10488 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 10547
Query: 1472 -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
++ R+ R+T P +F VP L G Y V A
Sbjct: 10548 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 10595
Query: 1523 GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
G GD SKP+ + I KPS + D NS+ + W P S + GY +
Sbjct: 10596 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 10652
Query: 1576 TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
K G + P+ +T+ + GL+ Y V A N +GES P +
Sbjct: 10653 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 10706
Query: 1633 PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
P P +K P L A G +R++ P K KE AP +
Sbjct: 10707 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10766
Query: 1686 SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
+ V+ V +K E+ +Y+L ++ S+ V L+ PPR V++
Sbjct: 10767 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 10824
Query: 1736 TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
+ + ++W+ + IT + V+ V + +P+ T K +S+ L G Y
Sbjct: 10825 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 10882
Query: 1790 KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
+ N R V +D P +L + + + W P +
Sbjct: 10883 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 10942
Query: 1839 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
ITGY+++Y++ G+ ++ + E +TGL+ G Y V K+E ++G
Sbjct: 10943 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 10992
Score = 102 bits (255), Expect = 3e-21
Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10138 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10196
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10197 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10244
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10245 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10304
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10365 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10422
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10423 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10478
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10479 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10538
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10539 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10598
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
SP + VF PP N E +TT + +TW P PR +G+ + +
Sbjct: 10599 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10656
Query: 1123 QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
G E R S V+GL G Y + + + E D V + V L
Sbjct: 10657 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10716
Query: 1175 SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
PP L L+AN DT L+ V+W++ T RI TP
Sbjct: 10717 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10775
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + H D + +P VSV + DK PP DL
Sbjct: 10776 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10821
Query: 1276 TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
+ I D+ +TW P +TN++V V + + + LS + + +L G
Sbjct: 10822 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 10880
Query: 1333 EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
+Y+ V++ Q+ P K LD P + D+ ++ W P
Sbjct: 10881 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 10939
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
+ ITGY + + E + V + +T L G Y + A N G +
Sbjct: 10940 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 10997
Query: 1437 SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
+ + I Q + VP +E+ L++ TVR+ I G P ++T
Sbjct: 10998 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11049
Query: 1497 PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
GS+ S TI + +Y ITV + A SK ++++
Sbjct: 11050 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11101
Query: 1540 TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
T +D P + + DV +++ W P SPV Y V T K+ G +
Sbjct: 11102 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11158
Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
+G +T++ I LQ EYV V A+N G PL T + P+P T +
Sbjct: 11159 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11218
Query: 1644 TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
T + + WT P +TGY + +E TG +N P + V+GL Y
Sbjct: 11219 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 11276
Query: 1699 EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
E V+A S+P+ ++ PP ++ D + T + W TK
Sbjct: 11277 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 11335
Query: 1749 ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
I G+ V+ G R K ++ ++ + GL G +Y+ + N P
Sbjct: 11336 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11393
Score = 102 bits (255), Expect = 3e-21
Identities = 255/1289 (19%), Positives = 459/1289 (35%), Gaps = 229/1289 (17%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17421 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17478
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17538
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17539 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17589
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17590 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17649
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17650 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17708
Query: 994 TTKLDAP------TNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P L V++T ++++ W P +++ GY V + +G +
Sbjct: 17709 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17764
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGV-----FTTLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP + P+NT
Sbjct: 17765 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL-PFNT 17823
Query: 1097 EVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
+ G + E+ V+ P + +V
Sbjct: 17824 YSIQA----------------------GEDLKIEIP------VIGRPRPNISWV------ 17849
Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+DG+ PL T +++E + VL + + D Y +T T + G
Sbjct: 17850 KDGE------------PLKQTTRVNVEETATSTVLHI--KEGNKDDFGKYTVTATNSAGT 17895
Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFT 1276
+L +V PG PP +RF
Sbjct: 17896 ATENLSVIVLE----------KPG---------------------------PPVGPVRFD 17918
Query: 1277 NIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLP 1330
+ D + ++W PP ++N++V K + +S + + + +T L
Sbjct: 17919 EVSADFVVISWEPPAYTGGCQISNYIVE----KRDTTTTTWHMVSATVARTTIKITKLKT 17974
Query: 1331 GTEYVVSVSSVYEQHESTPLRGR-----QKTGLDSPTGIDF-SDITANSFTVHWIAP--- 1381
GTEY + + +S PL + P G F + I+ + V W P
Sbjct: 17975 GTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVND 18034
Query: 1382 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
I GY + ++ + ++ P T L G EY + A E+ +
Sbjct: 18035 GGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA-----ENIVG 18089
Query: 1441 IGQQSTVS---------DVPRDLEVVAATPTSLLISWDAPAV----TVRYYRITYGETGG 1487
IG+ S VS D P E + T ++ + W PA + Y + +
Sbjct: 18090 IGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPD 18149
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
++ ++ T+SGL Y V A G+ S S +I R EID P+
Sbjct: 18150 GRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPN 18209
Query: 1547 QMQVTDVQDNSI--SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+D + + + + + G + + G +TA + + TI+
Sbjct: 18210 ASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18269
Query: 1605 TV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
V +Y++ + N G + V P P + LK T VT W
Sbjct: 18270 VVKDCIRTDGGQYILKL--SNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18327
Query: 1654 PPNVQLTGYRVR--VTPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYA 1704
PP +Q G + + K +T + +++ + + V+ L+ +Y V+ Y
Sbjct: 18328 PP-LQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYG 18386
Query: 1705 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVP 1760
+ + L S P + PP V+ T+ ++ ++W + I G+ ++
Sbjct: 18387 IGEPLESGPVT-ACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD 18445
Query: 1761 ANG--QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDAST 1811
G T + D+R +TGL G Y+ + N P DA
Sbjct: 18446 KEGVRWTKCNKKTLTDLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY 18504
Query: 1812 AIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV-- 1865
PSN + T+ +S+ ++W P A + GY+++ K + P G+
Sbjct: 18505 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQG 18563
Query: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ T+T L+ TEY + A+ + EP
Sbjct: 18564 KQFTVTKLKENTEYNFRICAINSEGVGEP 18592
Score = 102 bits (254), Expect = 4e-21
Identities = 337/1641 (20%), Positives = 581/1641 (35%), Gaps = 234/1641 (14%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 17016 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17074
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 17075 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17123
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 17124 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17183
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 17184 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17240
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 17241 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17300
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 17301 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17353
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 17354 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17410
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 17411 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17468
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 17469 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17527
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 17528 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17587
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 17588 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17642
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 17643 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17702
Query: 1258 PIS--DTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEED 1310
P+ D + A PP P + T++ + + W P + ++V P K E
Sbjct: 17703 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEK 17761
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
+ ++ S NAVV T L G EY V + E+ G P + +
Sbjct: 17762 WSIVAESKVCNAVV-TGLSSGQEYQFRVKAYNEK------------GKSDPRVLGVP-VI 17807
Query: 1371 ANSFTVHWIAPRATITGYRIRHHPE-----HFSGRPR------EDRVPHSRNSITLTNLT 1419
A T+ + + Y I+ + GRPR +D P + + T
Sbjct: 17808 AKDLTIQ-PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEET 17866
Query: 1420 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVA---------------ATPTSL 1464
T V+ I N + + ++ +L V+ + +
Sbjct: 17867 -ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 17925
Query: 1465 LISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
+ISW+ PA T + Y + +T + + +++T I+ LK G +Y ++A
Sbjct: 17926 VISWEPPAYTGGCQISNYIVEKRDTT-TTTWHMVSATVARTTIKITKLKTGTEYQFRIFA 17984
Query: 1521 VTGRGDS-PASSKPISINYR-TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S P SK + + Y E P VT + + + V+W + + GY +
Sbjct: 17985 ENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHL 18044
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
KN K T+ GL +EY V A+N G +P +
Sbjct: 18045 EQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 18104
Query: 1635 PTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSS 1686
P D + +T +++ +W P ++TGY V MK +
Sbjct: 18105 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18164
Query: 1687 VVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR--------VTDA 1735
VSGL+ +YE V A S P+ G +T + + P + V A
Sbjct: 18165 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 18224
Query: 1736 TET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYL 1793
ET + R K + D +T + IK ++ T+ TD Y+
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 1794 YTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARITGYIIK 1846
L++ +S P+ + P L+ T ++W PP A I+ YII+
Sbjct: 18284 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 18343
Query: 1847 YEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQ 1906
+ V + +T L PG EY V+A+ EPL + P
Sbjct: 18344 KRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL------ESGPV 18396
Query: 1907 LVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHG 1966
P+ P +V + + + VT G ++ G ++ ++ G
Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR--------DKEG 18448
Query: 1967 FRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH----LYPHGP 2013
R T T T +R R Y V E +G V Y LYP GP
Sbjct: 18449 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGP 18508
Query: 2014 GLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRVPG-TSTSA 2067
NP + + S +++W+ P D Y++ DE G
Sbjct: 18509 PSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQF 18566
Query: 2068 TLTGLTRGATYNIIVEALKDQ 2088
T+T L YN + A+ +
Sbjct: 18567 TVTKLKENTEYNFRICAINSE 18587
Score = 101 bits (252), Expect = 7e-21
Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21727
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21728 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21775
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21776 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21835
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 21836 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 21895
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 21896 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 21954
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 21955 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22010
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22011 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22069
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22070 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22127
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22128 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22182
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22183 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22242
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22243 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22302
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
T +L+ +EY+ V + V ES PI P VPP PT ++ +
Sbjct: 22303 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22359
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
M + W P D + ++ Y K E + V E + + +T L+ G E
Sbjct: 22360 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22418
Query: 1334 YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
Y ++ + V + E S P+ + +D+P + +D+T ++ ++ W AP + + GY
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22476
Query: 1389 RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
I P G R + + S N T+T L+ G Y ++A N + G +S
Sbjct: 22477 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22534
Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
T RD + D + + GG + G K
Sbjct: 22535 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22594
Query: 1506 SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
K + YT V R DS + +K +S+ + +D P ++
Sbjct: 22595 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22651
Query: 1550 VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
V+ V ++ W LP + +T Y V + +T+ + + +EG PT
Sbjct: 22652 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22699
Query: 1606 VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
+ YVV+ V A N G ES+P+V TIP+P + T +
Sbjct: 22700 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22759
Query: 1649 SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
QWT P +++ Y V K + ++ + D + + V+ LM Y+
Sbjct: 22760 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 22816
Query: 1701 SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
V A+ S P A ++ E PP RV D T+ +I+++W
Sbjct: 22817 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 22865
Score = 101 bits (251), Expect = 1e-20
Identities = 277/1345 (20%), Positives = 482/1345 (35%), Gaps = 189/1345 (14%)
Query: 692 VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
V R+D +T T ++ T + +P + VTEIT S ++W +
Sbjct: 16506 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 16565
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
+ + VE E Y + + S I L G Y V +E G
Sbjct: 16566 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 16622
Query: 803 LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
+ + P P TVD V S+ + W++P+ I Y ++ +E
Sbjct: 16623 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 16681
Query: 860 ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
E A +++L G +Y + AV E S P +VI+ + S
Sbjct: 16682 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16741
Query: 905 DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
+V +DL+ +EV K TI WT D +P+ Q I+
Sbjct: 16742 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 16784
Query: 962 AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
++T LS T+ Y A G+++ + K D P ++F + + ++
Sbjct: 16785 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 16844
Query: 1015 VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
+ W PP QIT Y + T + + + + L+ +EY + A
Sbjct: 16845 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 16904
Query: 1071 --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
G ES + +PG P+ T +++ ++VI W +P IG+ L
Sbjct: 16905 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 16964
Query: 1120 RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
+ + + + D+ L G+EY + + V + + + +
Sbjct: 16965 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 17023
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
P P + ++ N +T+ W + ITGY + P S V+
Sbjct: 17024 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17079
Query: 1226 HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
++ T L+ Y V K + PI+ + +P + P D
Sbjct: 17080 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 17136
Query: 1273 LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
N G +T R V P P+I+ K E+ A I +D +L
Sbjct: 17137 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 17189
Query: 1326 -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
+ G +Y++ S+V +S P+ + P G + + +T+ ++ W +P
Sbjct: 17190 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 17247
Query: 1384 TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR----- 1434
G I H+ + + R V NS+ +T L G EYV I+A+N
Sbjct: 17248 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17307
Query: 1435 -EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
E +P+L+ + P+ LEV S+ + W+ P I Y E S ++
Sbjct: 17308 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 17367
Query: 1493 EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
+ T ++GL +Y V A G S P ++ Y+ +
Sbjct: 17368 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 17425
Query: 1545 PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG-PTKTKTAGPDQTEMTI 1599
P+ + D NSI++ W S + GY V + T G T I
Sbjct: 17426 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 17485
Query: 1600 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
L EY + V A N G + T+V P D + L ++ V
Sbjct: 17486 SKLTEHQEYKIRVCALNKVGLGEA---TSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 17540
Query: 1660 TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
G R+ K P EI + + + V + + T+ + + L
Sbjct: 17541 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 17600
Query: 1706 KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
+++ S+ A V L+ PP+ V + + + + W + + +D +
Sbjct: 17601 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 17660
Query: 1762 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
+ + K S+ + L G Y + N+ PV +DA A + PS
Sbjct: 17661 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 17720
Query: 1818 --NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
L ++ T SL+ W+ P +R+ GY+++ + G+ +V + V A +T
Sbjct: 17721 KVTLTDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVT 17776
Query: 1872 GLEPGTEYTIYVIALKNNQKSEPLI 1896
GL G EY V A KS+P +
Sbjct: 17777 GLSSGQEYQFRVKAYNEKGKSDPRV 17801
Score = 98.6 bits (244), Expect = 6e-20
Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ +P++ P V + + N+ I+W P+ S I+ Y++ +
Sbjct: 18781 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18838
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K S +W T L + TI GL G Y ++ ++ + G + + PV
Sbjct: 18839 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 18889
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E P L + +V V + +R + + +E +
Sbjct: 18890 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 18946
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
T TS++I + K V Y++ I D P P +D+V
Sbjct: 18947 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19003
Query: 824 DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
SI + W+ P+ I+ Y + + + ++ S+ + L G +Y
Sbjct: 19004 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19063
Query: 880 I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
+ Y ES+ VV + P S P P + V T + + W P
Sbjct: 19064 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19117
Query: 932 -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
S V GY ++ ++ ++ I+ +T +V+GL G+ Y ++V+A G+ S
Sbjct: 19118 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19176
Query: 987 K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
K P+ A+ D P + N T +V ++W+ P A+ITGY L G
Sbjct: 19177 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19234
Query: 1033 --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
+T + ++Y N SVS+ SE T ++ +K
Sbjct: 19235 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19285
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
+ E P+ V ++ I EV + I P P I + K G+ +
Sbjct: 19286 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19342
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
T + + V Y + + R + KV+ PP LE N T
Sbjct: 19343 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19401
Query: 1191 -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
++SW R DI Y + T+ E + +SC L G EY
Sbjct: 19402 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19459
Query: 1244 --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
V+ Y V + ESV I VP PPT L T++ ++M + W+ P S +++
Sbjct: 19460 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19519
Query: 1298 FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
+++ KN ++ P D V T L G EY V + + E++PL
Sbjct: 19520 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19578
Query: 1351 RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
R L S P+ D + T+ W+ P A ITGY + + + +
Sbjct: 19579 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19636
Query: 1406 VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
+ R + T++ LT G EYV + ++N REE PL
Sbjct: 19637 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19692
Query: 1448 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
S++ + L V A ++ + + V + + + + + + S+++ TI
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19748
Query: 1506 -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
+ YT+T+ V A+S + + P+ + V DV S + W +
Sbjct: 19749 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19803
Query: 1564 PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
P + +PV Y + + T ++ + LQ Y V +N G
Sbjct: 19804 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19862
Query: 1621 SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
P +T P+P + L T ++ S+S W P ++ Y V K +
Sbjct: 19863 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 19922
Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
+K S+ VVSGL ++Y V+A S P + ++ L E + PP
Sbjct: 19923 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 19980
Query: 1729 ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
R + I IS + + F + N ++
Sbjct: 19981 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 20040
Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
++ D Y IT K ++ + VV+D P + + T S
Sbjct: 20041 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 20089
Query: 1829 LLVSWQPPR----ARITGYII 1845
+ + W+PP+ +++T YI+
Sbjct: 20090 VTLKWEPPKYDGGSQVTNYIL 20110
Score = 98.2 bits (243), Expect = 8e-20
Identities = 256/1304 (19%), Positives = 463/1304 (35%), Gaps = 171/1304 (13%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13009 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13068
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13069 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13116
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13117 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13174
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13175 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13226
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13287 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13338
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13339 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13397
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13398 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13455
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13515
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13516 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13576 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13633
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
+++ L G+EY V Y V + +S PI +P PPP ++ ++
Sbjct: 13634 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13691
Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
D++ +TW P + + K + + I D V T L G EY
Sbjct: 13692 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13749
Query: 1335 VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
V ++ P + +D P + +IT NS T+ W P+ +T
Sbjct: 13750 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 13809
Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
GY + + + V + T+T+L G +Y I A N G +P +
Sbjct: 13810 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 13865
Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
ST + + +D PT +L +T++ + ++ + G +
Sbjct: 13866 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 13922
Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
+ T S T+++ +K Y +T + + + P +
Sbjct: 13923 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 13982
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
++++V ++ W P SP+ Y + + T + + +Q
Sbjct: 13983 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14042
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTTI-----PAPTDL-KFTQVTPTSLSAQWTPP--- 1655
EY+ V A N G+ +P+ V + P P + + + VT + + W P
Sbjct: 14043 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14101
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++TGY V K+ ++ I V+GL + YE V A P+
Sbjct: 14102 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14161
Query: 1715 QGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT 1765
+ + L PP VTD T+ + +++W ITG+ V+ +
Sbjct: 14162 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEA 14221
Query: 1766 PIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
I+ T +R + + LQ Y + +ND P VI
Sbjct: 14222 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14265
Score = 97.4 bits (241), Expect = 1e-19
Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
T +VT L G Y F+V V+ +PL + LD PT+L+ + T ++
Sbjct: 19443 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19502
Query: 1014 LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
+ W+ P + +I+GY + RR + V V+K P+ +L+ S
Sbjct: 19503 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 19556
Query: 1061 EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
EY V G ++ SP P P + +TTI I W A
Sbjct: 19557 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 19616
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
P G+ + + S + + S G+ +SGLT G EYV+ ++ + D +
Sbjct: 19617 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19676
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
P + K P ++ E V +TV + P++ + + P +
Sbjct: 19677 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 19731
Query: 1218 GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
+ + + ++S T +N + +Y +++ V S+ + ++ PPT++
Sbjct: 19732 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 19789
Query: 1276 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
++ ++ ++W P + +PVKN E + +S ++N + +T
Sbjct: 19790 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 19842
Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
NL G Y VS E P ++ + P + + I+ +S ++ W+ P
Sbjct: 19843 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 19902
Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
G RI H+ + +++ V + T ++ L +EY + A N S
Sbjct: 19903 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 19961
Query: 1438 -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
P+LI +Q ++ P V A + D P ++T G
Sbjct: 19962 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 20018
Query: 1488 N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
F + TI+ LK V Y +T S + I+I +D+P
Sbjct: 20019 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 20074
Query: 1547 Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
+ ++D+ + S+++KW P S VT Y + + T+ +A +T M
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 20133
Query: 1599 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
+ L EY + A+N G S + VT T P P + T VT S++ W
Sbjct: 20134 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 20193
Query: 1653 TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
P + GY + + + K L ++ V+ + YE VYA
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 20253
Query: 1709 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
+P+ V ++ PPR R+TD ++ ++++SW+ ITG+ V+ +P
Sbjct: 20254 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 20313
Query: 1761 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
T T + + + I+GL + Y+ ++ N + + V+ T ID+
Sbjct: 20314 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 20369
Score = 96.3 bits (238), Expect = 3e-19
Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)
Query: 730 EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+IT S ++W D ++G+ VE + +D T +PDL+ G++
Sbjct: 7001 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7059
Query: 786 YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
Y+ V ++ GE + + + P PDP V D T SI + W P+
Sbjct: 7060 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7119
Query: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
+ I GY + P P + ++ L+ G Y + A+ S P
Sbjct: 7120 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7179
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
+E + D++ + VK + PE +T + D+I
Sbjct: 7180 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7239
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
+ +P + S TY + V GR + + K P +
Sbjct: 7240 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7298
Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
T+ + L+ W PPR ++IT Y + T + + + + L P EY
Sbjct: 7299 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7358
Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
+ A + G E +A+ + Q PP E +T+ + +TW +P
Sbjct: 7359 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7418
Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
G+ +L + + D+ + V GLT +Y + + + G+ +
Sbjct: 7419 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7477
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
+ P+ PP D G +V +W T P+ G + +E V
Sbjct: 7478 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7534
Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
+ T +L PGL EY+ V V ES P SD ++ PP L
Sbjct: 7535 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7594
Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
NI +T + W P +TN++V V+ + + + D +T L G
Sbjct: 7595 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7653
Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
+ YV V+ S Y + E + L T P + D+T + W P+
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7713
Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
I Y I + + + + +T++ GTE + A N G
Sbjct: 7714 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7773
Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
P L I ++ P DL V A + I+W P E G SP+
Sbjct: 7774 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7821
Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
+ V G++ ++ G+ P +Y + V AV G S+P I
Sbjct: 7822 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 7877
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ P D++ + I V S +R P + D+
Sbjct: 7878 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 7937
Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
M + + +E SV A +N G + + V +P P D+K + +T +
Sbjct: 7938 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 7997
Query: 1647 SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
S W PP T V + + G I + + S V L+ +Y V
Sbjct: 7998 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8057
Query: 1704 ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
A+ ++ G L+N PP V + T +TI+W+
Sbjct: 8058 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 8112
Query: 1750 TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
I G+ ++ + A G+ +R + + +YT GL+ G +Y+ + +++ +R+
Sbjct: 8113 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 8171
Query: 1803 SPVVIDASTAIDAP 1816
+P A IDAP
Sbjct: 8172 TPPT-KAVDPIDAP 8184
Score = 94.4 bits (233), Expect = 1e-18
Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 12203 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12260
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 12261 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12308
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 12309 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12368
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 12369 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12428
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 12429 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12488
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 12489 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12540
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 12541 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12600
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 12601 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12658
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
L EY+ + A+ SP K T T P PP E VT++T+ + W P
Sbjct: 12659 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12716
Query: 1110 APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
G K+ G + + AP ++ + +GL +Y +
Sbjct: 12717 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12774
Query: 1152 -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
TI D + K + + TN+ L+A + TVSW++
Sbjct: 12775 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 12834
Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
T P G + + ++ CT + N +Y ++
Sbjct: 12835 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 12879
Query: 1254 KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
K S I ++ PP ++ + D ++W PP ++TN++V + +
Sbjct: 12880 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 12937
Query: 1311 VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
A++S + + + L+ G EY + + + P+ K D P D
Sbjct: 12938 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 12997
Query: 1366 -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
S+IT + TV W P + ITGY + + +R P ++ T L
Sbjct: 12998 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13057
Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
GTEY + A+N + P G+ S S P +V T +S+ +SW
Sbjct: 13058 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13112
Query: 1469 DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
PA + Y + ++ V+ +P + K+ ++GL Y VYAV
Sbjct: 13113 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13171
Query: 1523 GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
G D P P I E + + ++ T + ++++ PV G
Sbjct: 13172 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13228
Query: 1578 PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
+ P G D T + E + +Y++++ +N G+ + + V
Sbjct: 13229 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13286
Query: 1630 TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
P P ++ +++ S W PP + + Y V+ E+ +
Sbjct: 13287 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 13345
Query: 1685 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
+S V+ L Y V+A + P + V + P +V ++++ +I
Sbjct: 13346 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 13405
Query: 1743 SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
W+ I G+ VD + + QR +K Y+ L G +Y + N+
Sbjct: 13406 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 13463
Query: 1799 NARSSP--VVIDASTAIDAP 1816
N +P + + A + AP
Sbjct: 13464 NGEGTPSEITVVARDDVVAP 13483
Score = 94.0 bits (232), Expect = 2e-18
Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)
Query: 710 TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
TV+ TP P+ E +I +S + W D + Y L ++ + +++
Sbjct: 8298 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 8354
Query: 767 DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
+ ST ++ L+ G++Y+ V + G +++ PDAP P V
Sbjct: 8355 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8414
Query: 820 DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
+ V S++V+W+ P+ +PI GY + E +ST + + L G+
Sbjct: 8415 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 8471
Query: 877 NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
+T ++ V + P + D + P P + + + + + W PP
Sbjct: 8472 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 8531
Query: 932 --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ GY VD ++ N +++ + + T E+ G Y +V AV+ E
Sbjct: 8532 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 8588
Query: 987 KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
P Q T +LD T+ + WT ++
Sbjct: 8589 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 8648
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
R+ + NVG + K LR + Y ++ G++ + V
Sbjct: 8649 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 8696
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
F P + P T ++ W+ + GF + + ++ + + ++
Sbjct: 8697 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 8754
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
++GL G EY + +V+ + P V V PL PPT+ + E
Sbjct: 8755 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 8812
Query: 1188 TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
T +T+ W+ + I GY I + + + + +S +NL Y
Sbjct: 8813 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 8869
Query: 1245 VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
V V + ES +P++ I PPT ++ DT++V P I D+T
Sbjct: 8870 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 8929
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
+ E V E P+D + + +E +S +V E + + +
Sbjct: 8930 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 8986
Query: 1357 GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
G P + +DI A S + W AP G I H+ + + R
Sbjct: 8987 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 9045
Query: 1402 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
+ + + ++ + L P +Y + A+N S + + D P
Sbjct: 9046 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 9105
Query: 1452 RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
+V+A T S+L+SW P + Y + E G +P+ + + G +
Sbjct: 9106 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 9165
Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
+ L GV Y A+ G P S S P ++ + PS +V D +S
Sbjct: 9166 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 9223
Query: 1558 ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
IS+ W P + SP+ GY V + G T K PD+ T E + P ++ Y
Sbjct: 9224 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 9280
Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
V A N +GES+P T IPA TD++ + AQ V G ++R+
Sbjct: 9281 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 9335
Query: 1667 ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
TPK E G K ++ A +SS +++ + + S+
Sbjct: 9336 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 9395
Query: 1704 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
A K+ + A V ++ PP+ +V+D T + +SW+ + I G+ ++
Sbjct: 9396 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 9454
Query: 1760 PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
+G+ + + PD S T + L Y + N PV I +TA D
Sbjct: 9455 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 9512
Query: 1816 -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
P L+ T N++ +SW+PP+ + +T YI++ ++ G+ +
Sbjct: 9513 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 9572
Query: 1864 GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
V E T+ L G EY V A+ S+P
Sbjct: 9573 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9605
Score = 93.6 bits (231), Expect = 2e-18
Identities = 266/1257 (21%), Positives = 449/1257 (35%), Gaps = 180/1257 (14%)
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
++TS + DL + V +E G +T A + P D ++ TS+
Sbjct: 20923 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 20982
Query: 828 VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
++ W++P + IT Y + E + + + +T + +S L+ ++A
Sbjct: 20983 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21041
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
E S PV I T + + +P ++ ++ +VT+ Y+ P
Sbjct: 21042 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21096
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
+ G LP+ + F + +T K HG + + ++ P
Sbjct: 21097 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21154
Query: 1003 ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
++F +V++ W P +IT Y + T + +
Sbjct: 21155 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21214
Query: 1047 SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
+ + + + NL +EY + A + P + + PG P VT
Sbjct: 21215 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21274
Query: 1102 TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
+ +TW + GF + + + TS SG +GL G++Y + +
Sbjct: 21275 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21334
Query: 1154 QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
D V+P+ PP T +++ +T +T+ W R I GY
Sbjct: 21335 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21392
Query: 1207 RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
I +QGN D S C T LSPG Y +V T+ +S
Sbjct: 21393 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447
Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
I T VPP GP+ LV+ PV +D E+
Sbjct: 21448 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21502
Query: 1315 SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
+ + +T++L T V V +V ++ S + K + G
Sbjct: 21503 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21559
Query: 1364 --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
I F++IT T+ W AP A IT Y I + + ED+ S T
Sbjct: 21560 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21617
Query: 1417 NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
L G EY + A+N GR + P++ Q TV D P E T S+ ++W
Sbjct: 21618 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21677
Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
P E+ G S +Q++ + P S++ ++GL G +
Sbjct: 21678 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21725
Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
Y V A G PAS I R ++ P+ ++VTD ++S++W
Sbjct: 21726 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21785
Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
+ GY + + K +T T+ LQ EY V A N +G+
Sbjct: 21786 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21845
Query: 1627 T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
T AV + AP D F Q A +++L Y+ R TP + P
Sbjct: 21846 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 21900
Query: 1678 INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
++L D ++ S L V A KY ++V ++ S+ V L+ PP
Sbjct: 21901 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 21957
Query: 1730 ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
D T + T+ W I + V+ A+ ++ + K + + + L
Sbjct: 21958 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 22017
Query: 1786 GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
G Y + +N+ P I A+ P L + T+ +S +++W P
Sbjct: 22018 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 22077
Query: 1838 ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+RITGY+++ + GS V T+ L TEY V A + SEP
Sbjct: 22078 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 22132
Score = 92.8 bits (229), Expect = 3e-18
Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20130
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20131 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20188
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20189 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20247
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20248 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20306
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20307 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20363
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20364 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20423
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20424 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20483
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20484 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20540
Query: 1245 VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
V V P+ SD+++ PP T I ++M V W+ P D+
Sbjct: 20541 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20600
Query: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
+ + + K+ L + D +T L ++Y V +V++ + S P
Sbjct: 20601 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20660
Query: 1353 RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
+ P G I +D T +S T+ W P + +TGY + E G E
Sbjct: 20661 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20716
Query: 1405 RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
++ + T NL PG Y + A+N + P+ + + D+ DL
Sbjct: 20717 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20776
Query: 1455 EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
+V T D P VT R G S S S
Sbjct: 20777 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20832
Query: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
TI + + G G+ +S+ + + +D P+ ++QV V ++++
Sbjct: 20833 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 20887
Query: 1561 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
W P SP+ Y + ++ T + + T + L + V A+
Sbjct: 20888 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 20945
Query: 1616 NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
N G +P T +PAP DL T TS+ WT P+ +T Y V
Sbjct: 20946 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21005
Query: 1668 PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
K E+T I+ + + VS L + E V+A + S P G +T E +
Sbjct: 21006 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 21062
Query: 1726 PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
P + V + + ++ K + + D +P ++ +T
Sbjct: 21063 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 21122
Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
S + G Y + L DNA V + PS +RF +S++
Sbjct: 21123 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 21178
Query: 1831 VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
+SW P IT Y I+ + ++V T + L EY V A
Sbjct: 21179 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 21237
Query: 1887 KNNQKSEPLI 1896
S+PL+
Sbjct: 21238 NRYGVSQPLV 21247
Score = 91.3 bits (225), Expect = 1e-17
Identities = 267/1256 (21%), Positives = 445/1256 (35%), Gaps = 161/1256 (12%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
S+ + T +S ++SW EY + +G Q + + I ++ ++
Sbjct: 20973 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 21031
Query: 787 IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
V +++ E+ L ++ T + P VD D + VR Y+
Sbjct: 21032 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 21091
Query: 843 IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
PS+ L L E T N +TLS ++ + +N V
Sbjct: 21092 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 21151
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
I T G P P ++F E+ V + W PE +T Y ++ +
Sbjct: 21152 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21207
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
++R TF +V L Y F+V A + S+PL A+ ++ P
Sbjct: 21208 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 21266
Query: 1005 FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
+ N T + + W P +++TG+ + ++ N P S +Y L
Sbjct: 21267 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 21326
Query: 1059 ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
+Y + A SP FT P P +VT TI + W P R G
Sbjct: 21327 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 21386
Query: 1116 K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
+ QG E R V + + V+GL+PG Y + I I
Sbjct: 21387 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 21432
Query: 1167 VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
V +SPP+ +E P+ G++ S E + R
Sbjct: 21433 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21492
Query: 1212 PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
T + G +E+ ++ D T + + VYTV+ S V +
Sbjct: 21493 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
DT V P +RFTNI + M + W P + +T++++ ED
Sbjct: 21553 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 21609
Query: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
E + S A+ L N G EY VS+V + PL Q T D+P +
Sbjct: 21610 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21663
Query: 1367 SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
S+IT NS T+ W P + I Y + + + + + P S +T LT G
Sbjct: 21664 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21723
Query: 1422 TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
EY ++A N P LI + V+ P ++V + T++ + W P
Sbjct: 21724 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21783
Query: 1475 VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
I Y + + ++ + K+ T++ L+ G +Y V A+ G+GDS
Sbjct: 21784 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 21843
Query: 1528 --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
+ K + E+D + + T V S++ ++ T V + P +
Sbjct: 21844 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 21903
Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
+ +T+E ++ +N SG V P P + F V
Sbjct: 21904 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 21963
Query: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
T S + W P + G R+ EK + I+ V+ L Y
Sbjct: 21964 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22022
Query: 1700 VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
V A+ + P + + E +PPRR V D ++++ ++W ITG
Sbjct: 22023 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 22082
Query: 1754 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
+ ++ ++ + ++T+ L T+Y+ + ND S P +S I
Sbjct: 22083 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22141
Query: 1814 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1866
P P + L IT +I K GSP VP RP P VT
Sbjct: 22142 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22183
Score = 90.1 bits (222), Expect = 2e-17
Identities = 140/634 (22%), Positives = 237/634 (37%), Gaps = 93/634 (14%)
Query: 1358 LDSPTG---IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHS 1409
LDSP + S +T T+ W P+ A IT Y + R + E P
Sbjct: 22641 LDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTL 22700
Query: 1410 RNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
S +T L EY+ + A+N E P++ T+ P E V
Sbjct: 22701 --SYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEH 22758
Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT-----------------IS 1506
++I W P E+ G + + + V + + ++
Sbjct: 22759 IIIQWTKP------------ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVT 22806
Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWL 1563
L G DY V AV G+S S I+ R PS +V D +SIS+ W
Sbjct: 22807 SLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 22866
Query: 1564 P----SSSPVTGYRVTTTPKNGPGPTKTKT-AGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
+ + GY + K+ + T A TE T+ L+ +Y V A N
Sbjct: 22867 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 22926
Query: 1619 G---------ESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1669
G E +P+ + + + DLK T S + V ++G V
Sbjct: 22927 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM---VSVSGRPPPVITW 22983
Query: 1670 EKTG---PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS--RPAQGVVTTLENV 1724
K G + I +S S+++ + +Y+ Y ++ S + A +V +
Sbjct: 22984 SKQGIDLASRAIIDTTESYSLLIVDKV--NRYDAGKYTIEAENQSGKKSATVLVKVYDTP 23041
Query: 1725 SPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
P +V + + ++TI+W T + + V+ A + T K Y I
Sbjct: 23042 GPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRI 23101
Query: 1781 TGLQPGTDYKIY-----LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP 1835
+GL GT Y +Y + + +S V+ + + P+ L + T +++ ++W+
Sbjct: 23102 SGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEK 23160
Query: 1836 PR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1891
P +R+TGY+++ K G+ V +P V E T+T L G +Y + A
Sbjct: 23161 PLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGV 23220
Query: 1892 SEP-----LIGRKKTDELP--QLVTLPHPNLHGP 1918
SEP + + LP L T+P +H P
Sbjct: 23221 SEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVP 23254
Score = 89.7 bits (221), Expect = 3e-17
Identities = 131/594 (22%), Positives = 227/594 (38%), Gaps = 77/594 (12%)
Query: 1414 TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
T+T L G EY+ + A N ++P+ + V P ++ + +
Sbjct: 6652 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 6711
Query: 1466 ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
++W+ P + Y I + TV +AT++ + G +Y+ V A
Sbjct: 6712 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 6771
Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
G S+ + I++PS + +D +S+ +KW P SP+ GY +
Sbjct: 6772 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6831
Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
+ + + + GL+ +Y+ V A+N +G S P + I
Sbjct: 6832 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 6885
Query: 1635 PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
P V PT LSA + PN V TGY R T +TG +
Sbjct: 6886 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 6945
Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
+ + +V+S + + + +Y LK + G V + S P+ + D
Sbjct: 6946 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 7002
Query: 1736 TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
T+ ++ ++W + +TG+ V+ + +T + +T+ L G +Y
Sbjct: 7003 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 7062
Query: 1792 YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
+ N P +D +T D P N+++ T NS+ ++W PP+ +RI
Sbjct: 7063 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 7122
Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
GYI++ GS P T+ +TGLE G Y V AL S+P +
Sbjct: 7123 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP---SRP 7178
Query: 1901 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQP 1954
T+E+ + T P + LDV T G I+LP T +P
Sbjct: 7179 TEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTGKP 7221
Score = 89.4 bits (220), Expect = 4e-17
Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)
Query: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
S P E+ E P+ P S P+ + K+I + W+P KN +G E G
Sbjct: 7773 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 7830
Query: 662 -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
+NS IK LK GVV + + + ++ G E + + P
Sbjct: 7831 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 7889
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
T+ ET + S+ + + V VS + L+ + D
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 7942
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ + +P + I + ++ G + ++ P D + +S
Sbjct: 7943 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8000
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
+ W P+ PI Y + + + + E S T+ DL P +Y + AV
Sbjct: 8001 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 8060
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
+ + ++ P D++ T +TI W PP S + GY ++
Sbjct: 8061 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 8120
Query: 941 VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
I GE + +PI T GL G Y F+V A + S+P A
Sbjct: 8121 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 8174
Query: 995 TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
TK +DAP T+L+ V D L + W I +
Sbjct: 8175 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 8233
Query: 1032 GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
L RR Q + V P + + N + Y + + G
Sbjct: 8234 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 8293
Query: 1074 ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
++P V T PG I ++ +T+++ W P G + + E +
Sbjct: 8294 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 8349
Query: 1134 DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
DS IVV+ L G EY++ ++ + P V+K + P PP
Sbjct: 8350 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 8408
Query: 1179 -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
+ + + + + V W + I GY + N + + + + + D
Sbjct: 8409 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 8467
Query: 1236 NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
L GL Y V + P SD P PP P R T+ T+ + W P
Sbjct: 8468 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8527
Query: 1290 PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
P ++ + V V E + + G +Y + VS+V E
Sbjct: 8528 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8587
Query: 1347 STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
P + T + P ++ + + G +R P +GRP
Sbjct: 8588 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 8638
Query: 1405 RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
+V ++ + + N+ +E ++ I A N + V
Sbjct: 8639 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 8696
Query: 1448 SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
DVP DL+ V L++W P E G S + F +
Sbjct: 8697 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 8744
Query: 1500 ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
+S I+GL G +Y V A G P P+ I +D
Sbjct: 8745 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 8800
Query: 1545 PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
P ++ T+ ++I++ W SP+ GY + + P + T +E
Sbjct: 8801 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 8860
Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
L Y V A N GES+P ++P ++ +V PT LS + V
Sbjct: 8861 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 8913
Query: 1658 QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
+ G V + P + TG PM +I + + + + + + TK EVS V
Sbjct: 8914 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 1703 YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
K T T + + + NV SPPR VTD + ++W +
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 9031
Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
IT + +D A+ + + + Y I L P Y+ + Y ++D +S
Sbjct: 9032 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 9091
Query: 1804 PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
VVI D P + LA T S+LVSW PP + ITGY ++ + GSP V
Sbjct: 9092 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 9151
Query: 1859 PRPRPGVTEATITGLE 1874
R +T+ + G+E
Sbjct: 9152 --SRAPITKVGLKGVE 9165
Score = 89.4 bits (220), Expect = 4e-17
Identities = 289/1431 (20%), Positives = 507/1431 (35%), Gaps = 177/1431 (12%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
YG G+ P++ P ++ + + NS + W P+ S I +YI+ +
Sbjct: 16616 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 16673
Query: 647 PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
K+S +W E L + I L G Y +++++ + G + S + P+
Sbjct: 16674 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 16724
Query: 707 TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
+ + E + S V + +S T++ + L +
Sbjct: 16725 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 16783
Query: 767 DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
L T S+ G +Y + V + G+++ + PD P P D V
Sbjct: 16784 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 16841
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
SI + W+ P IT Y + + ++ ++ ++ L+ G +Y I+
Sbjct: 16842 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 16901
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
A EN+ ++ + P P F ++ + I W P S V G
Sbjct: 16902 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 16959
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
Y ++ N I +T + L G+ Y F+V+A V G+ SK
Sbjct: 16960 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 17019
Query: 994 TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
D P + + + + ++WT P + ITGY + G+ + + +
Sbjct: 17020 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17079
Query: 1049 -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
+++ + L Y ++A G P +TG T P S+ P + +
Sbjct: 17080 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 17136
Query: 1101 TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
T +V + P P I + G + + + T ++V
Sbjct: 17137 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17196
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
Y ++ + P+ KV+ PP + +++W + DI+
Sbjct: 17197 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 17256
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
Y + T+ + V + T L G EY V+ Y V + ES P+
Sbjct: 17257 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17314
Query: 1260 --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
+ ++P PP L TNI D+M V W P S + + ++ + + +
Sbjct: 17315 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 17372
Query: 1318 P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
+D + +T L EY VS + E +P K PT
Sbjct: 17373 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 17432
Query: 1368 DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
D T NS T+ W P + I GY + E E ++ + + +T L
Sbjct: 17433 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 17488
Query: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
T EY + + ALN + +G+ ++V + + + A P L S + VR
Sbjct: 17489 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 17542
Query: 1477 -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
RI G +P ++ + T + ++ GV+YT Y +
Sbjct: 17543 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 17601
Query: 1525 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
S + S +++ P + V +V+ +S + W P + V Y +
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 17661
Query: 1581 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
++ +T +E L Y V A+N G P+ V+ A P P
Sbjct: 17662 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 17719
Query: 1636 TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
+ T V+ TS S W P ++ GY V + PK EK + E + + VV
Sbjct: 17720 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 17775
Query: 1690 SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
+GL +Y+ V A + S P GV +T ++ P A E
Sbjct: 17776 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 17835
Query: 1738 ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
ISW E + T V+ + I+ K D YT+T
Sbjct: 17836 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 17894
Query: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
T +N S +V++ P +RF + + +++SW+PP +I+ YI
Sbjct: 17895 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 17944
Query: 1845 IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
++ + +V T IT L+ GTEY + A KS PL
Sbjct: 17945 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPL 17994
Score = 89.4 bits (220), Expect = 4e-17
Identities = 339/1648 (20%), Positives = 590/1648 (35%), Gaps = 249/1648 (15%)
Query: 611 PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
P + TE P+ P +S + W P S I+ Y+L R K S W EA
Sbjct: 22040 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22098
Query: 658 TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
GH ++T++ L YE ++ + G+ E R F++ P T +TG
Sbjct: 22099 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22154
Query: 714 ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
T A S ++ S V+ +++E +E D + T
Sbjct: 22155 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22206
Query: 774 SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
++ + D + G +Y + + + G ++ ++ P P V V S V+
Sbjct: 22207 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22264
Query: 831 WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
W P+ IT Y + S + +N + ++ L ++Y+ + +
Sbjct: 22265 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22324
Query: 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
V + ES P++ + P + T P + V+ ++I W P S + GY
Sbjct: 22325 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22378
Query: 938 RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
V+ N + ++P + +VTGL G+ Y F+ +A VS E S+P+
Sbjct: 22379 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22437
Query: 991 AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
AQ +DAP + + T STV + W+ P +++ GY +
Sbjct: 22438 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22495
Query: 1030 ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
TV G ++ V ++K + SE T V + PKA
Sbjct: 22496 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22551
Query: 1080 -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
G T++ GS + + P P+I + G + E + T
Sbjct: 22552 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22603
Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
+ V+ YT+ V + ++ KV+ P L + + T+
Sbjct: 22604 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22662
Query: 1194 SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
+W S + G IT ++ + L V+ S L EY V V
Sbjct: 22663 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22720
Query: 1251 KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
VP+ I A +P PP G + + + W P S +++N+LV
Sbjct: 22721 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22780
Query: 1301 -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
R++ V + V D + +T+L+ G +Y V++V S P
Sbjct: 22781 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22833
Query: 1354 QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
P+ D T +S ++ W P I GY + + R
Sbjct: 22834 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 22893
Query: 1403 EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
RN+ T+ +L G +Y + A+N G E I + V ++P DLE+
Sbjct: 22894 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 22952
Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
++ I A R+ +G PV ++ G A+ + + Y++
Sbjct: 22953 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23005
Query: 1518 V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
+ Y + S S + + Y T PS ++V +V +S+++ W
Sbjct: 23006 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23064
Query: 1563 -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
+ +PV Y + + KT T +T I GL Y V +N G
Sbjct: 23065 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23123
Query: 1622 QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
+P + V+ +P P L+ VT ++++ W P +LTGY +
Sbjct: 23124 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23183
Query: 1674 PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
MK + L P V+ L +Y E V ++T+T+ Q V+ T++
Sbjct: 23184 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 23243
Query: 1724 VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
+ P++ A E I I+ R F + + + ++ K +
Sbjct: 23244 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 23303
Query: 1781 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
T ++ +Y + L + + VI ++ S+ +SW+PP
Sbjct: 23304 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 23363
Query: 1838 -ARITGYIIKY---EKPG-SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
A ++GY+++ +PG P E V R + T L G EY V A N+
Sbjct: 23364 GAPLSGYVVEQRDAHRPGWLPVSESVTR-----STFKFTRLTEGNEYVFRVAA--TNRFG 23416
Query: 1893 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSG 1951
+ + E + +P P PE L + + +T +P D G G Q+ G
Sbjct: 23417 IGSYLQSEVIECRSSIRIPGP----PETLQIFDVSRDGMTLTWYPPEDDG-GSQVTGY-- 23469
Query: 1952 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPH 2011
V ++ + + R P T T R+R + E ++ I P
Sbjct: 23470 ---IVERKEVRADRWVRVNKVPVTMT--RYRSTGLTEGLEYEHRVTAINARGSGKPSRPS 23524
Query: 2012 GP--GLNPNASTGQEALSQTT--------ISWAPFQD-----TSEYIISCHPVGTDEEPL 2056
P ++P A G+ + T ++W+ +D + Y+I V E
Sbjct: 23525 KPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK 23584
Query: 2057 QFRVPGTSTSATLTGLTRGATYNIIVEA 2084
P TLT L +GA Y V A
Sbjct: 23585 CNTTPTKIREYTLTHLPQGAEYRFRVLA 23612
Score = 88.2 bits (217), Expect = 8e-17
Identities = 177/778 (22%), Positives = 292/778 (37%), Gaps = 127/778 (16%)
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
T ++L G EY V V S P + D P +PP DL+ TN+
Sbjct: 9580 TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9639
Query: 1279 -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
G +TW APP D PV + V +L + + V+ +
Sbjct: 9640 VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9693
Query: 1332 TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
T + +V+++ + L + G P G I F ++A+ T+ W P+ +
Sbjct: 9694 TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9751
Query: 1385 ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
IT Y I H S P+E + T+ L G EYV I+A N
Sbjct: 9752 ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9804
Query: 1435 --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
+ P +V P V + T S+ ++W+ P V Y + +T
Sbjct: 9805 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9864
Query: 1489 -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
P++ T+ S ++GL G DY VYA+ G PAS S P +
Sbjct: 9865 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 9921
Query: 1540 TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
P +VTD +S ++W P S VTGY V + K K T
Sbjct: 9922 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 9981
Query: 1596 EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
++ + GL+ Y V A N +G +P T V ++K V+P L A
Sbjct: 9982 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 10035
Query: 1655 PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10095
Query: 1703 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10155
Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10156 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10213
Query: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10214 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10273
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 1916
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10274 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10324
Score = 84.7 bits (208), Expect = 9e-16
Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 6689 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6748
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 6749 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6803
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 6804 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6863
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 6864 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 6923
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 6924 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 6979
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 6980 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7034
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 7035 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7094
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 7095 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7152
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
L G Y V + S P T I AV
Sbjct: 7153 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7211
Query: 1272 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
+L T G ++TW I + + V + V + SD G
Sbjct: 7212 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 7262
Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
T + +V+ + K G P D +D+T S + W PR + IT
Sbjct: 7263 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7320
Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
Y + R + V H +S T L P EY+ + A N +
Sbjct: 7321 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 7373
Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
SP+ Q P LE T ++ ++W P + Y + + + V
Sbjct: 7374 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7433
Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
+ +P +T + GL Y V A + G G S++PI I + ID P
Sbjct: 7434 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 7491
Query: 1547 QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
+ V DV S+ + W + + Y V K G G T+ + GL
Sbjct: 7492 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 7550
Query: 1603 QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
EY V A N +GES+P L + + P L+ +T + +WT P
Sbjct: 7551 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 7610
Query: 1656 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
+T Y V + G + ++ + V+ L E S+Y + +
Sbjct: 7611 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 7664
Query: 1712 RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
Q T +E+ PP V D T+ + + W I + ++
Sbjct: 7665 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 7724
Query: 1758 AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
G ++ +T PD ++ +T + GT+ + + N+ P + D
Sbjct: 7725 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 7783
Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
++ P +L + ++W+PP + I GY ++ G+ V RP
Sbjct: 7784 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7843
Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
+ G+ P EY + V A+ SEP
Sbjct: 7844 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7874
Score = 83.6 bits (205), Expect = 2e-15
Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)
Query: 619 TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
T S +S +QWN P S + Y L + +NS+ K P + GL+ GV
Sbjct: 15853 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 15912
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
YE ++ + G P + P P E++ +T +S
Sbjct: 15913 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 15957
Query: 736 FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ W ++G+ VE + EG + T + L+ +Y V
Sbjct: 15958 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16017
Query: 792 QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
+ G S ST TA D PP ++D +IVV + A I G I
Sbjct: 16018 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16075
Query: 846 SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
P+++ + L TA + +D + + +S +++ + RS
Sbjct: 16076 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16129
Query: 905 DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
TV P P + V VT K T+ W PP + D+I + RL
Sbjct: 16130 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16186
Query: 956 IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
+ + +VT L G Y F++ AV+ ES+P+ A+ + DAP
Sbjct: 16187 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16246
Query: 1004 QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
+ T +++V W P + +I GY L G+ R + + +G +
Sbjct: 16247 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16305
Query: 1056 LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
E+ VS G E SP + +PG P ++T +++ ++W+
Sbjct: 16306 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16365
Query: 1112 RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
G K V + + +I V L EY + I + G
Sbjct: 16366 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16425
Query: 1160 QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
+ D P V L +P +L LE + L V + TP++ ++
Sbjct: 16426 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16482
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
+G+ ++ V + +S DN++ Y+ YT+ +S ++ ++
Sbjct: 16483 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16537
Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
PP +L+ T I D++ +TW PP +D + + Y K E + A + + N+
Sbjct: 16538 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16596
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
+ L G Y V++ E P + + P I D+T NS ++ W
Sbjct: 16597 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16656
Query: 1381 PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
P + I Y + +H RV + +TNLT G EY+ +VA+N +
Sbjct: 16657 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16714
Query: 1437 S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
S P + D+ + +V A + S+ + D P IT+ + G P
Sbjct: 16715 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16772
Query: 1491 VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
+++ T V S T+S G Y ITV V G+ K SI T +D
Sbjct: 16773 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16824
Query: 1544 KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
KP ++ DV SI++ W P +T Y V TTT + T +T
Sbjct: 16825 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 16884
Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
+ + L+ EY ++A+N G ES P+V P P F T ++
Sbjct: 16885 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 16938
Query: 1645 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
S+ QW P + GY + + K + L +YE
Sbjct: 16939 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 16998
Query: 1701 SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
VYA + ++ + PP IT+ W ITG+
Sbjct: 16999 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17058
Query: 1755 QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
V+ P R +K + +T++GL Y+ + N
Sbjct: 17059 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17102
Score = 82.0 bits (201), Expect = 6e-15
Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)
Query: 628 IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+AP S ++ + + + +NS+ K T P Y GL G+ Y+ ++ +
Sbjct: 21278 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21337
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G S+P + T +P P + ++T + + W
Sbjct: 21338 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21382
Query: 745 DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
V Y + + +++ T S + L PG +Y + IS
Sbjct: 21383 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21442
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
+ S I+ T P P V+ + D I+ R +A + G + +
Sbjct: 21443 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21497
Query: 847 PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
VE + + + S +L ++ + + +Y VE S I+ + TP
Sbjct: 21498 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P ++F +T K+T+ W P + +T Y ++ +
Sbjct: 21557 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21612
Query: 960 TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
++ + L G Y F+V AV+ GR +S P+ AQ Q T DAP + N T +++
Sbjct: 21613 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21671
Query: 1014 LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
+ W P + G + + R + + +SK P+ L +EY +
Sbjct: 21672 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21730
Query: 1067 VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
+A P A+G+ ++ PG T+ ++TT+ + W+ I
Sbjct: 21731 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21789
Query: 1114 GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
G+ + + + G+ +V +++ V+ L G EY + + + + D+ V
Sbjct: 21790 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21848
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
+ + T L+ + + V ++ Y+ TPT SL +H
Sbjct: 21849 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 21908
Query: 1227 ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
S T N + +Y ++V K S+ + ++ PP + F ++ +
Sbjct: 21909 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 21967
Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
+ W P +D + Y K E +S + + +L G Y VS
Sbjct: 21968 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22026
Query: 1340 SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
+V E P + P +D D + +S + W+ P + ITGY +
Sbjct: 22027 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22086
Query: 1392 HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
+ G H++ + T+ L TEY + A N S S +
Sbjct: 22087 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22143
Query: 1451 PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
P+ DL + A +P ++ + AP VT + + ET S
Sbjct: 22144 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22199
Query: 1495 TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
T ++T T+ G Y +T+ ++ A K S+ I +P +
Sbjct: 22200 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22251
Query: 1549 QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
+V+ V S + W + +T Y + ++G + + +T++ + L
Sbjct: 22252 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310
Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
+EY V ++N G S+PL + +P APT + V+ ++S +W P
Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22370
Query: 1656 -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
++ GY V + +KE + + V+GL+ +Y+ YAL S+ +
Sbjct: 22371 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22430
Query: 1715 QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
+ + V P R VTD T +T+++ W + G+ ++ P +
Sbjct: 22431 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 22490
Query: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
TI D +T+T L G Y+ + N
Sbjct: 22491 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 22523
Score = 79.3 bits (194), Expect = 4e-14
Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)
Query: 1412 SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
S +T L G EY I+A+N E P++ V D P+ EV T S++
Sbjct: 16198 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 16257
Query: 1466 ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
+ W+ PA + Y + + G + + ++GL DY V A
Sbjct: 16258 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 16317
Query: 1522 TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
G SP S+ + + + P+ +V D+ +S+ + W + GY V
Sbjct: 16318 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 16377
Query: 1575 TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
+ G T G ++T + +E L EY + A N +G + +V+
Sbjct: 16378 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 16437
Query: 1627 TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
+ DL+ ++ + R TP+ K G +++ +
Sbjct: 16438 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 16493
Query: 1683 DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
+SS L +Y+ Y L +++ ++ A V L+ SPP +VT+ T+ ++
Sbjct: 16494 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16553
Query: 1741 TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
+I+W I + V+ A ++ S+ I LQ G Y +
Sbjct: 16554 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16613
Query: 1797 NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
N+ P I + P + T NS+ +SW P ++I YI++ +
Sbjct: 16614 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16673
Query: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
S R + +A IT L G EY V+A+ +S+P
Sbjct: 16674 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 16717
Score = 78.6 bits (192), Expect = 7e-14
Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19571 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19630
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19631 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19682
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19683 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19734
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19735 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19792
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19793 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19852
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 19853 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 19909
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 19910 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 19963
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 19964 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20014
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20015 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20134
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20135 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20193
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20249
Query: 1250 V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
K S P+ I A PP ++R T+I +++ ++W P
Sbjct: 20250 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20294
Score = 75.5 bits (184), Expect = 6e-13
Identities = 200/944 (21%), Positives = 346/944 (36%), Gaps = 118/944 (12%)
Query: 908 PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
P L EVT K + W PP G ++D V RL + + T
Sbjct: 15060 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 15116
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
+VT L G Y F+V AV+ +PL ++ + D P N + T +++V
Sbjct: 15117 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15176
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
W P + + + RR + Q + + +Y + L EY ++A
Sbjct: 15177 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15236
Query: 1071 -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
+P T F T +PG PP N V +T +I I W + G+
Sbjct: 15237 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15293
Query: 1116 KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
+ + + E + VT +G S ++GLT EY I + G+ P
Sbjct: 15294 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15352
Query: 1169 KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K + PP L + + R P I G G SL++
Sbjct: 15353 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15411
Query: 1228 DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
SS T + ++ Y TV++ +S ++ ++ PP DL+ + ++
Sbjct: 15412 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15471
Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
+TW PP +D + + Y K E + + ++ + + + L G Y V +
Sbjct: 15472 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15530
Query: 1341 VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
E P + P I D+T NS ++ W P + I GY +
Sbjct: 15531 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15590
Query: 1393 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
+ V T+T L G EY + A N E + +Q +V + +
Sbjct: 15591 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15645
Query: 1453 DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
DL + A T T L + D P + +T+ + N P+++ T ++ST
Sbjct: 15646 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 15703
Query: 1504 --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
++ +K + Y V + + + +++ +DKP +++ +V +S
Sbjct: 15704 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15760
Query: 1558 ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
I++ W P S + Y V K T + TI+ L+ EY
Sbjct: 15761 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15817
Query: 1612 VYAQNPSGE-----SQPLVQTAVTTIPAPTDLK-FTQVTPTSLSAQWTPP----NVQLTG 1661
+ A+N G+ S+P V +P P T + S+ QW P ++ G
Sbjct: 15818 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 15877
Query: 1662 YRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GV 1717
Y + KE+ + ++N P + +GL +YE V A +P++
Sbjct: 15878 YHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSEC 15935
Query: 1718 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
+ PP R T ++T+ W+ T ITG+ V+
Sbjct: 15936 YVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 15979
Score = 75.1 bits (183), Expect = 7e-13
Identities = 125/581 (21%), Positives = 213/581 (36%), Gaps = 71/581 (12%)
Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVAATPTSLLISWD 1469
+ + N T S+ +N E + + + V D P DL+V T TS +SW
Sbjct: 12166 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVR--VLDTPGPVSDLKVSDVTKTSCHVSWA 12223
Query: 1470 AP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
P V +Y + E + T K++ ++ L PG +Y V AV G
Sbjct: 12224 PPENDGGSQVTHYIVEKREADRKT-WSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 12282
Query: 1526 DSPASSKP---ISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
+ P ++ + +E D P +++VT++ NS ++ WLP + + GY +
Sbjct: 12283 PGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 12342
Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTTIPA 1634
+ P T+ + + + GL+ +Y V A+N G S P V A +
Sbjct: 12343 EEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLP 12402
Query: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
P L Q+T + G ++R+ P VV S +
Sbjct: 12403 PKILMPEQITIKA-------------GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12449
Query: 1695 ATKYE-VSVYALKD---------TLTSRPAQGV------VTTLENVSPPRRA-RVTDATE 1737
K + S+ +KD +LT+ + G V ++ PP+ ++D
Sbjct: 12450 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12509
Query: 1738 TTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
++SW E IT + V+ + + S + L PG +Y +
Sbjct: 12510 DACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRV 12569
Query: 1794 YTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGY 1843
N S P+ A P N R + + V+W P + I GY
Sbjct: 12570 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 12629
Query: 1844 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 1903
+I+ ++ S TE GL G EY+ + AL S P K T+
Sbjct: 12630 LIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPP---SKPTEY 12686
Query: 1904 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGI 1944
+ + + P PE++DV + + P +D G+ I
Sbjct: 12687 VTARMPVDPPG--KPEVIDVTKSTVSLIW-ARPKHDGGSKI 12724
Score = 72.0 bits (175), Expect = 6e-12
Identities = 284/1399 (20%), Positives = 497/1399 (35%), Gaps = 195/1399 (13%)
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
G + I+ H++ + T + P S TV+ + P V+EI S
Sbjct: 10774 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10830
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
++W D Y + E D P +ATS L G +Y+ V
Sbjct: 10831 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 10889
Query: 794 SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
++ G + + A D PP P D VD T + + W++P +PITGY +
Sbjct: 10890 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 10949
Query: 844 VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
Y EG+ + N ++ LQ G Y + A V T + I+ +
Sbjct: 10950 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11007
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
P S + D++ +E VK P + + G V G + +
Sbjct: 11008 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11062
Query: 957 SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
+ F+ V + + T +++ VS+ SK + A T LD P + ++ T
Sbjct: 11063 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11120
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ + W PP+ + + Y + TR+ + G S +K + +LQ EY
Sbjct: 11121 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11180
Query: 1066 LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
+ A P T + S P P T++TE ++WT +P G
Sbjct: 11181 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11240
Query: 1115 FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
+ + R G T + V+GL G Y + + G + +P + +
Sbjct: 11241 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11300
Query: 1171 ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
+ P PP N L+ + + W + + I GY + Q N + +
Sbjct: 11301 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11359
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
Q + L G EY + E P +++++I PP +L T
Sbjct: 11360 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11419
Query: 1280 PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 11420 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11477
Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 11478 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11528
Query: 1382 R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
+ IT + + + + G R + NL EY + A N
Sbjct: 11529 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11586
Query: 1434 ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
++P+L P +L + T + + W P ++Y G
Sbjct: 11587 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11646
Query: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
+ + K T + + V+ I + V + + S K + + ++ KP
Sbjct: 11647 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11704
Query: 1546 SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
V D +S V + + + R+ + P P T D T++T
Sbjct: 11705 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11754
Query: 1599 IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
I+ + ++ ++ V A N +G V P P +LK V+
Sbjct: 11755 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 11814
Query: 1647 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
+ W PP G ++ EK K + + S++V+ G V E + Y +
Sbjct: 11815 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 11872
Query: 1707 DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
++ G T + V P VT ++ +T+ W ++ITG
Sbjct: 11873 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 11932
Query: 1754 FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
+ ++ + P+ ++ P+ R + L P +Y+ + N+ + S PV
Sbjct: 11933 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991
Query: 1806 VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
V D P+N R + TT +S+ + W P A I GY+++ + P E
Sbjct: 11992 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12051
Query: 1859 PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 1914
R E T+T L+ EY V A NQ +G + EL + + P
Sbjct: 12052 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----VGIGRPAELKEAIK-PKEI 12103
Query: 1915 LHGPEILDVPSTVQKTPFV 1933
L PEI D+ ++++K V
Sbjct: 12104 LEPPEI-DLDASMRKLVIV 12121
Score = 68.2 bits (165), Expect = 9e-11
Identities = 218/1049 (20%), Positives = 384/1049 (36%), Gaps = 174/1049 (16%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6654
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 6655 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6712
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 6713 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6771
Query: 1251 KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
P + T V PP +L ++ ++++ W PP S L +
Sbjct: 6772 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6831
Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
R K+ + + P + +T L G +Y+ VS+ + S P D
Sbjct: 6832 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 6890
Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
D++A + I P +P + D+V + + + + L+
Sbjct: 6891 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 6950
Query: 1420 PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
E V+S + + L L + T+S P++L+ T S+ ++
Sbjct: 6951 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 7010
Query: 1468 WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
W+ P + G SP+ + V + + T+ L G
Sbjct: 7011 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 7058
Query: 1513 DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
+Y V A G G+ +P++++ + D P ++ D NSI + W P
Sbjct: 7059 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 7118
Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
S + GY V P+ G K G +T+M + GL+ Y V A N G S+P
Sbjct: 7119 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7175
Query: 1624 LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
T AV T AP L T L A T P ++T + + K
Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235
Query: 1670 EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
+ K I + P S+V + + + + + Y ++ A VV L+
Sbjct: 7236 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 7288
Query: 1726 PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
PP +TD T + ++W + IT + V+ + + + T+K ++
Sbjct: 7289 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 7346
Query: 1780 ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
T L P +Y +Y + + ++SP I A D P+ L T +++ +
Sbjct: 7347 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 7404
Query: 1832 SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
+W P + ITGY ++ P + + T + GL +Y V+A
Sbjct: 7405 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 7464
Query: 1887 -----KNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTG 1941
K ++ +EP++ + D P P P + DV T + + T P +D G
Sbjct: 7465 LAGPGKPSKSTEPILIKDPIDP-------PWPP-GKPTVKDVGKTSVRLNW-TKPEHDGG 7515
Query: 1942 NGIQ--------------------LPGTSGQQPSV--GQQMIFEEHGFRR---TTPPTTA 1976
I+ +P T P + GQ+ F + + P +
Sbjct: 7516 AKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPS 7575
Query: 1977 TPIRHRPRPYPPNVGEEIQIGHIPREDVD 2005
P+ R + YPP+ +++ +I + D
Sbjct: 7576 DPVLCREKLYPPSPPRWLEVINITKNTAD 7604
Score = 62.8 bits (151), Expect = 4e-09
Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)
Query: 675 VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
+ E I++++ + R++ T ++S T N V + P P+V +++
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20084
Query: 731 ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
IT S + W D S L E + ++ +T T + + L G +Y
Sbjct: 20085 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20144
Query: 787 ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
N + IS+ + + + T P P P V V SI V W P + G
Sbjct: 20145 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20202
Query: 843 IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
V +E L + AN + + + + G+ Y +YA P
Sbjct: 20203 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20259
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
+ D PR+++ +++ V++ W P S +TGY V+ +LP
Sbjct: 20260 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20317
Query: 952 QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
+ + T + ++GL+ Y F+VFA + G S P T +D+
Sbjct: 20318 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20377
Query: 1008 ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ T +V++ T +L G++ + P Y + L ++ ++
Sbjct: 20378 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20433
Query: 1066 LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
L+ ++ S AT L +PG P + VT I + W P
Sbjct: 20434 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20493
Query: 1110 APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
A G K+ + E R V S + I + + G EY++ ++ + +
Sbjct: 20494 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20553
Query: 1159 GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
E D+ + N VTP P P + N +TV W R DI+GY +
Sbjct: 20554 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20609
Query: 1213 TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
L+E + + T L+ +Y V V + E +D I
Sbjct: 20610 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20667
Query: 1264 IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
P PP +R + ++ + W+ P +T ++V + EE
Sbjct: 20668 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20726
Query: 1320 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
V++NL PG Y VS+V + P+ + K L++P ID S
Sbjct: 20727 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20785
Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
+ ++ R P + ++ +R SI T+ +T +Y
Sbjct: 20786 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20845
Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
+++I G +S + + + L+V + ++ + WD P + I Y
Sbjct: 20846 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905
Query: 1485 TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
++ + ++V K ++T L K + + G G+ +++P+
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 20962
Query: 1540 TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
E+ P + + D S+ + W S +T Y V + G G AG +
Sbjct: 20963 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21019
Query: 1595 T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
T E+ + L+ V+A+N G S P+ TI P +K +TP LS
Sbjct: 21020 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 21069
Query: 1653 TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
P Q+T G+ V + K P I+ D + S + +K E + ++K+
Sbjct: 21070 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21129
Query: 1709 LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
+ V T+ + PP + R + ++ +SW +
Sbjct: 21130 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21189
Query: 1751 --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
IT + ++ QT + R ++ + L +Y+ + N S P+V
Sbjct: 21190 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21248
Query: 1808 DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
A P T + + ++W P + +TG+ ++ ++ S +
Sbjct: 21249 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 21308
Query: 1858 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
V E TGL G +Y V A + S P
Sbjct: 21309 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21345
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 8995 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9052
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9053 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9105
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9106 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9159
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9160 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9219
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9220 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9279
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9280 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9311
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24229 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24283
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24284 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24343
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24344 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24403
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24404 CENLGGESEWSEISEPI--TPKSD 24425
Score = 37.7 bits (86), Expect = 0.13
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24612 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24669
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24670 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24729
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24730 EVDETREVSMT 24740
Score = 35.8 bits (81), Expect = 0.50
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)
Query: 1534 ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
+ + + + DKP+ V + + NS + W P + S +T Y V +
Sbjct: 24218 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24277
Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
++ T I L Y V AQN G S PL ++V I +P + T
Sbjct: 24278 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24337
Query: 1642 QVTPTSLSAQWTPP 1655
VT S W PP
Sbjct: 24338 AVTKDSCVVAWKPP 24351
Score = 31.6 bits (70), Expect = 9.4
Identities = 38/169 (22%), Positives = 66/169 (39%), Gaps = 21/169 (12%)
Query: 2027 SQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081
S ++SW+ +D + Y I TD+ + T+T T+TGL A Y
Sbjct: 23847 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 23906
Query: 2082 VEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESG 2138
+ A D + E VV + ++P+ + ++S +V +WE+ G
Sbjct: 23907 IIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDG 23961
Query: 2139 FKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2187
K + LG+ + + S W N K D+Q G ++ T
Sbjct: 23962 GK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24002
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 147 bits (371), Expect = 1e-34
Identities = 149/595 (25%), Positives = 252/595 (42%), Gaps = 54/595 (9%)
Query: 1367 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1424
++ TA S T+ W + ++ Y I+H P++ +E D V +R S+ L+P ++Y
Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 389
Query: 1425 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1476
+VA+N G P+L + S PRD++ + T++L+ W + P ++
Sbjct: 390 EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 449
Query: 1477 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
YR+ Y T + + V S+ T TI L P Y++ V A T GD P SS
Sbjct: 450 GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508
Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
I +P + + SI + W P S + Y + K+G + +
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 566
Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA-----PTDLKFTQVTPTSL 1648
T ++GL+P Y + A++P G + + T+ + P D+ T + TS+
Sbjct: 567 GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 626
Query: 1649 SAQWTPPNVQ-----LTGYRVRVT--PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1701
W PP V+ +T Y ++ T E P + + + D++ ++ L T+Y ++
Sbjct: 627 LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 1702 VYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET-----ITG 1753
V A D + V + T E+V PPR+ V T++ +SWR+ I G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 1754 FQVDAV-----PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL---YTLNDNARSSPV 1805
+QV V GQ ++ + D + I+GLQP T Y + + T D ARS P
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPK 806
Query: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPP---RARITGYIIKYEKPGSPPREVVPRPR 1862
++ + A+ L T N+ L+ W PP + GY +K+ + P +
Sbjct: 807 LVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSE 866
Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHP-NLH 1916
T T + G Y + A E ++ K +P+ V P NLH
Sbjct: 867 K-EDHFTATDIHKGASYVFRLSARNKVGFGEEMV---KEISIPEEVPTGFPQNLH 917
Score = 139 bits (351), Expect = 2e-32
Identities = 228/1008 (22%), Positives = 390/1008 (38%), Gaps = 145/1008 (14%)
Query: 752 VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
++ E SEE D+ +Y + + + P Y+ + ++ + I T+ P
Sbjct: 192 LQIEQSEESDQGKYECVATNSAGTRYS--APANLYVRELREVRRVPPRFSIPPTNHEIMP 249
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+ T V V+W E + E ++P N + L+D++
Sbjct: 250 GGSVNITCVAVGSPMPYVKWML--------------GAEDLTPEDDMPIGRNVLELNDVR 295
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPP 930
Y ST VI+ T ++ +P P V E T +T+ W
Sbjct: 296 QSANYTCVAM-------STLGVIEAIAQITVKA--LPKPPGTPVVTESTATSITLTWDSG 346
Query: 931 ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESK 987
Y + E + + T V GLSP Y F+V AV++ G S+
Sbjct: 347 NPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSE 406
Query: 988 PLTAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR---AQITGYRL--TVGLTRR-GQP 1039
P+ Q + + AP ++Q + +T+LV+W P QI GYR+ T+ T+
Sbjct: 407 PVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNW 466
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
++NV S + NL P Y+V ++A + P ++ + Q G P N +
Sbjct: 467 MKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAE 525
Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
+ET+I+++WTP PR ++L + + GE R S + GL P Y +
Sbjct: 526 PESETSILLSWTP-PRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFR 584
Query: 1153 IQVLRDGQERDAPIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD----I 1203
+ R Q A P +PP ++ + T +L VSW+ I
Sbjct: 585 LAA-RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL-VSWQPPPVEKQNGII 642
Query: 1204 TGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPI 1259
T Y I T +G+ E + + +D + + L EY ++V D ES+ +
Sbjct: 643 TEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSV 702
Query: 1260 SDTIIPAVP--PPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEEDVAE 1313
VP PP + + +++V+W +P P+ + + V Y ++N E +
Sbjct: 703 LIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQ 762
Query: 1314 LSISPSDNA----VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG------ 1363
+ A ++++ L P T Y ++V++ + + R K L S TG
Sbjct: 763 PMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGA----RSKPKLVSTTGAVPGKP 818
Query: 1364 -IDFSDITANSFTVHWIAPRAT---ITGYRIRHHPEHFSGRPREDRVP-------HSRNS 1412
+ + N+ + W P T + GYR++ R+D P +
Sbjct: 819 RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG--------RKDMEPLTTLEFSEKEDH 870
Query: 1413 ITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1468
T T++ G YV + A N G E + + + P++L T TS+ +SW
Sbjct: 871 FTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSW 930
Query: 1469 DAPAVTVRY-----YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1522
P + R Y + Y + P+++ VP +T T++GLKP Y + V A T
Sbjct: 931 QPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPAD-TTMTLTGLKPDTTYDVKVRAHT 989
Query: 1523 GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGP 1582
+G P S S+ +RT + V V + VK + +S + + + P+N
Sbjct: 990 SKGPGPYSP---SVQFRT-------LPVDQVFAKNFHVKAVMKTSVLLSWEI---PENYN 1036
Query: 1583 GPTKTKTAGPD----------QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
K D T+ I L+P Y + G S +Q VT
Sbjct: 1037 SAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSY---SFVLTNRGNSAGGLQHRVTAK 1093
Query: 1633 PAPTDL--KFTQVTPTSLSAQWT------PPNVQLTGYRVRVTPKEKT 1672
AP L K + T+L T P N + GY + + P +K+
Sbjct: 1094 TAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKS 1141
Score = 136 bits (343), Expect = 2e-31
Identities = 167/690 (24%), Positives = 288/690 (41%), Gaps = 79/690 (11%)
Query: 1259 ISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
I+ + A+P PP T ++ +TW ++ +++++ P +EE E+
Sbjct: 314 IAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEID-G 372
Query: 1318 PSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPL--RGRQKTGLDSPTGIDFSDITAN 1372
+ + L P ++Y VV+V+++ S P+ + ++ +P + +++
Sbjct: 373 VATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSST 432
Query: 1373 SFTVHWIAPR---ATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
+ V W P I GYR+ + P + V S+ + T+ NL P Y V
Sbjct: 433 TILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVK 491
Query: 1428 IVALNGREESPLL----IGQQSTVSDVPRDLEVVAATPTSLLISWDAP-AVTVRYYRITY 1482
++A + PL + Q+ V P + + + TS+L+SW P + T+ Y + Y
Sbjct: 492 VLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY 551
Query: 1483 GETGGNSPVQEFTV-PGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 1541
+ G + Q T+ PG+ + + GLKP Y + A + +G ++++ I+ RT
Sbjct: 552 KD-GEHGEEQRITIEPGT--SYRLQGLKPNSLYYFRLAARSPQGLGASTAE---ISARTM 605
Query: 1542 IDKPS----QMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTTPKNGPGPTKTKTAG- 1591
KPS + T SI V W P + +T Y + T +G + G
Sbjct: 606 QSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGI 665
Query: 1592 -PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA--PTDLKFTQVTP 1645
D T+ +E L+ EY ++V A G + + T +P+ P ++ V
Sbjct: 666 PSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNS 725
Query: 1646 TSLSAQWTPP-----NVQLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVA 1695
TS+ W P + Q+ GY+V E P +K++ LA D+ +++SGL
Sbjct: 726 TSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA-DAQDMIISGLQPE 784
Query: 1696 TKYEVSVYALK---DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET-- 1750
T Y ++V A D S+P +V+T V R + T I W +T
Sbjct: 785 TSYSLTVTAYTTKGDGARSKPK--LVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFG 842
Query: 1751 -ITGFQV-----DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
+ G+++ D P T ++ + K D +T T + G Y L N
Sbjct: 843 PLQGYRLKFGRKDMEPL---TTLEFSEKED--HFTATDIHKGASYVFRLSARNKVGFGEE 897
Query: 1805 VVIDASTAIDAPS----NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPR 1855
+V + S + P+ NL TT S+ +SWQPP IT Y + Y P
Sbjct: 898 MVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLL 957
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
+ P T T+TGL+P T Y + V A
Sbjct: 958 PMEQLIVPADTTMTLTGLKPDTTYDVKVRA 987
Score = 131 bits (330), Expect = 7e-30
Identities = 158/701 (22%), Positives = 294/701 (41%), Gaps = 72/701 (10%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
++T + ST + T P + VTE TA+S ++W S + + VS + +++
Sbjct: 299 NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 358
Query: 755 ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
+ + E Y ++ AT+ ++ L P Y V ++ G + ++ TS+
Sbjct: 359 K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 416
Query: 810 APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
AP D + T+I+V+W P+ P I GYR+ Y+ P+ ++ + +
Sbjct: 417 PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 476
Query: 865 VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
T+ +L P Y++ + A + + S+ + VI Q TG P P + + ++
Sbjct: 477 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 529
Query: 921 VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
+ + WTPP S + Y + V GEHG QR+ I T + GL P YYF++
Sbjct: 530 TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 585
Query: 978 FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
A S G + ++A+ Q+ P ++ + + +++LV W PP + IT Y
Sbjct: 586 AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645
Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
+ T +P + PS +KY L L+ +EY +++ A P++ V
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 705
Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEAPRE--- 1130
T + S PP E V T++ ++W +P P G+++ + GE +
Sbjct: 706 TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765
Query: 1131 ---VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEA 1184
+ +D+ +++SGL P Y T+ DG +V+ P +
Sbjct: 766 KDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHT 825
Query: 1185 NPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T ++ T + GYR+ + + +LE D + T + +
Sbjct: 826 QMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR 885
Query: 1245 VSVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
+S E + + + IP P P +L +++++W PP + + +
Sbjct: 886 LSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITK 944
Query: 1302 YSPVKNEEDV----AELSISPSDNAVVLTNLLPGTEYVVSV 1338
Y+ + + ++ E I P+D + LT L P T Y V V
Sbjct: 945 YTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 985
Score = 105 bits (263), Expect = 4e-22
Identities = 156/688 (22%), Positives = 258/688 (37%), Gaps = 93/688 (13%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
T S S + W++ P +S YI++ +PKNS +KE I G + Y++ GL P Y
Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 389
Query: 678 EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
E +++++ G S PV T T E P S +++++ +
Sbjct: 390 EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 435
Query: 738 VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
V W + + G+RV Y + ++ + + I +L+P + Y V V
Sbjct: 436 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 495
Query: 794 SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
+ G+ L I +QT P P + + +TSI++ W+ P++ I Y +VY
Sbjct: 496 TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 555
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
G + + E S L L+P Y + A + + + + T +S
Sbjct: 556 HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 612
Query: 910 PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
P+D+ + + + W PP +T Y + V+ GE + E+
Sbjct: 613 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 662
Query: 965 TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
G+ T Y +++ +H G + L+ T D P+ ++
Sbjct: 663 LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 722
Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV-----SKYPLRN 1055
VN T +V V W P QI GY++ G+P+ + V +
Sbjct: 723 VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISG 780
Query: 1056 LQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTIVITWTP--- 1109
LQP + Y TV+ KG+ K V TT PG N T +I W P
Sbjct: 781 LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTALIQWHPPVD 839
Query: 1110 --APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERD 1163
P G++L R E + + + G YV+ + G+E
Sbjct: 840 TFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMV 899
Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGN 1219
I P P NLH E T V +SW+ + IT Y + N
Sbjct: 900 KEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLYRDINIPLLP 958
Query: 1220 SLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
+ +V AD ++ T L P Y+V V
Sbjct: 959 MEQLIVPAD-TTMTLTGLKPDTTYDVKV 985
Score = 99.4 bits (246), Expect = 4e-20
Identities = 173/748 (23%), Positives = 277/748 (37%), Gaps = 105/748 (14%)
Query: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLE---VVAA 1459
ED +P RN + L ++ Y ++ G E+ Q TV +P+ V +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIA----QITVKALPKPPGTPVVTES 334
Query: 1460 TPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTIT 1517
T TS+ ++WD+ V YY I + +E + G +T +++GL P DY
Sbjct: 335 TATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDYEFR 392
Query: 1518 VYAVTGRGDSPASSKPIS-INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP---VTGYR 1573
V AV G P S ++ + + P +Q + +I V+W P + GYR
Sbjct: 393 VVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYR 452
Query: 1574 VTTTPKNGPGPTK-----TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES------Q 1622
V T PT+ K D TI L P Y V V A G+ Q
Sbjct: 453 VYYTMD----PTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508
Query: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
+ QT V P + K + TS+ WTPP V + G + I + P
Sbjct: 509 VITQTGVPG--QPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEP 566
Query: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----------PPRRARV 1732
+S + GL + Y L +R QG+ + +S PP+
Sbjct: 567 -GTSYRLQGLKPNSLYYFR-------LAARSPQGLGASTAEISARTMQSKPSAPPQDISC 618
Query: 1733 TDATETTITISWRT-----KTETITGFQVDAVPANGQTPIQRTI---KPDVRSYTITGLQ 1784
T + T+I +SW+ + IT + + +G+ I D Y + L+
Sbjct: 619 TSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLE 678
Query: 1785 PGTDYKIYLYTLND---NARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSWQPP--- 1836
T+Y+I + D S V+I + + + P + A S+ VSW+ P
Sbjct: 679 KWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPN 738
Query: 1837 --RARITGYIIKY------EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
+I GY + Y E G P + V + I+GL+P T Y++ V A
Sbjct: 739 KQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA--DAQDMIISGLQPETSYSLTVTAYTT 796
Query: 1889 NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQ-- 1945
R K P+LV+ + G L + T T + HP DT +Q
Sbjct: 797 KGDG----ARSK----PKLVSTTGA-VPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGY 847
Query: 1946 --LPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRED 2003
G +P + +E F TAT I H+ Y + ++G
Sbjct: 848 RLKFGRKDMEPLTTLEFSEKEDHF-------TATDI-HKGASYVFRLSARNKVGFGEEMV 899
Query: 2004 VDYHLYPHGP-GLNPNASTGQEALSQTTISWAP------FQDTSEYIISCHPVGTDEEPL 2056
+ + P G N + + +SW P ++Y + + P+
Sbjct: 900 KEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPM 959
Query: 2057 QFRVPGTSTSATLTGLTRGATYNIIVEA 2084
+ + T+ TLTGL TY++ V A
Sbjct: 960 EQLIVPADTTMTLTGLKPDTTYDVKVRA 987
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 146 bits (368), Expect = 3e-34
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
A + +EG +G++++ CT G G+ C + D
Sbjct: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
Score = 145 bits (365), Expect = 6e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 146 bits (368), Expect = 3e-34
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 217 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 276
Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 277 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 334
Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
A + +EG +G++++ CT G G+ C + D
Sbjct: 335 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 383
Score = 145 bits (365), Expect = 6e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 244 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 295
Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 296 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 353
Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 354 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 404
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 144 bits (364), Expect = 8e-34
Identities = 155/608 (25%), Positives = 256/608 (42%), Gaps = 70/608 (11%)
Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1429
TA S T+ W + Y + + P + + + ++ L+P +EY + +
Sbjct: 344 TATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVS 403
Query: 1430 ALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRYYRI 1480
A+N + P G+Q+ S PR+++ + T++++ W+ P +R YR+
Sbjct: 404 AVNSIGQGPPSESVVTRTGEQAPAS-APRNVQARMLSATTMIVQWEEPVEPNGLIRGYRV 462
Query: 1481 TYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
Y PV Q+ V S T T+ L YT+ V A T GD P S PI +
Sbjct: 463 YY-TMEPEHPVGNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSD-PIQVK 519
Query: 1538 YRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
+ + +P ++ + SI++ W P + G +T P T
Sbjct: 520 TQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPT-TS 578
Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQ--PLV-QTAVTTIPA--PTDLKFTQVTPTSLSAQ 1651
+E L+P EY + A++P G P+V Q + + P+ P D+K V T++
Sbjct: 579 YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVS 638
Query: 1652 WTPP-----NVQLTGYRVRVTPKEKTGPM-KEIN-LAPDSSSVVVSGLMVATKYEVSVYA 1704
W PP N L GY VR P P KE+N + P ++ +++ L T+Y ++ A
Sbjct: 639 WRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVA 698
Query: 1705 LKDTLTSRPAQGVVT-TLENV--SPPRRARVTDATETTITISWRTKTE-----TITGFQV 1756
+ + VV T E+V +PPR+ T I + WR+ I G+QV
Sbjct: 699 HTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQV 758
Query: 1757 -----DAVPANGQTPIQRTIKPDVRSYT---------ITGLQPGTDYKIYL--YTLN-DN 1799
+ A G I+ + D + T IT LQP T Y I + YT+ D
Sbjct: 759 HYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDG 818
Query: 1800 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPR 1855
ARS P V+ A+ L T SLL W+PP ++ GY +++ + S P
Sbjct: 819 ARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPL 878
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 1915
+ P P T +G+ G Y + A +S +G +E +++++P
Sbjct: 879 ATLEFP-PSEDRYTASGVHKGATYVFRLAA-----RSRGGLG----EEAAEVLSIPEDTP 928
Query: 1916 HG-PEILD 1922
G P+IL+
Sbjct: 929 RGHPQILE 936
Score = 124 bits (311), Expect = 1e-27
Identities = 195/889 (21%), Positives = 339/889 (38%), Gaps = 113/889 (12%)
Query: 752 VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
++ E SEE D+ +Y + + + V P Y+ + ++ + IL S P
Sbjct: 201 LQIESSEETDQGKYECVATNSAGVRYSS--PANLYVRELREVRRVAPRFSILPMSHEIMP 258
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+ T V V+W + E + E ++P N + L+D++
Sbjct: 259 GGNVNITCVAVGSPMPYVKWMQ--------------GAEDLTPEDDMPVGRNVLELTDVK 304
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
Y + E+ V Q P++ P E T +TI W
Sbjct: 305 DSANYTCVAMSSLGVIEA---VAQITVKSLPKAPGTP-----MVTENTATSITITWDSGN 356
Query: 932 -SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
V+ Y ++ + G + + I+ ++ + GLSP Y V AV+ + P
Sbjct: 357 PDPVSYYVIEYKSKSQDGPYQIKEDITTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSE 415
Query: 991 AQQT-----TKLDAPTNLQFVNETDSTVLVRW---TPPRAQITGYRLTVGLTRR---GQP 1039
+ T AP N+Q + +T++V+W P I GYR+ + G
Sbjct: 416 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNW 475
Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
+++NV S+ + +L YTV ++A + P + + Q G P N
Sbjct: 476 QKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAE 534
Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
+ET+I ++W+P PR I ++L R G + S VV L P EY +
Sbjct: 535 ARSETSITLSWSP-PRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFR 593
Query: 1153 IQVLR-DGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERSTTPD-----I 1203
+ G P+V + P +PP ++ + T +L VSW R P+ +
Sbjct: 594 LAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL-VSW-RPPPPETHNGAL 651
Query: 1204 TGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPI 1259
GY + P + E + + + L +Y ++ V ES P+
Sbjct: 652 VGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPV 711
Query: 1260 ---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEED-- 1310
+D +P+ PP + + +RV W +P P + + V Y ++ E
Sbjct: 712 VVRTDEDVPSAPP-RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARG 770
Query: 1311 --------VAELSISPSDNA---VVLTNLLPGTEYVVSVSSVYEQHESTPLRGR----QK 1355
+A+ D A +V+TNL P T Y ++V++ + + + + +
Sbjct: 771 PPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKG 830
Query: 1356 TGLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRN 1411
L PT + S W P T + GYR++ E + + P S +
Sbjct: 831 AVLGRPT-LSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLE-FPPSED 888
Query: 1412 SITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA-ATPTSLLI 1466
T + + G YV + A + G E + +L + T P+ LE A+ ++L+
Sbjct: 889 RYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLL 948
Query: 1467 SWDAPAVTVRY-----YRITYGETGGNSPVQEFTVP-----GSKSTATISGLKPGVDYTI 1516
W P R Y + E G P +E +P G+++ T+ GLKP Y +
Sbjct: 949 RWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDL 1008
Query: 1517 TVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW 1562
V A T RG P S + YRT + P +V + S+ + W
Sbjct: 1009 QVRAHTRRGPGPFSP---PVRYRTFLRDQVSPKNFKVKMIMKTSVLLSW 1054
Score = 105 bits (262), Expect = 5e-22
Identities = 179/808 (22%), Positives = 327/808 (40%), Gaps = 100/808 (12%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
++T + S+ V T P + VTE TA+S ++W S + D VS + +EY
Sbjct: 308 NYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEY 367
Query: 755 ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTA 810
+ S+ D P + T T +I L P +Y + V ++ G+ +S++ T +
Sbjct: 368 K-SKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAP 426
Query: 811 PDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYSPSVE---GSSTELNLPETANS 864
AP + + T+++V+W P P I GYR+ Y+ E G+ + N+ ++
Sbjct: 427 ASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSL-L 485
Query: 865 VTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDV 921
T+ L Y + + A V + S P+ ++ + G P P +L+ ++
Sbjct: 486 TTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ-QGVP-----GQPMNLRAEARSET 539
Query: 922 KVTIMWTPP-ESAVTGYRVDVIPVNLPGEHGQRL--PISRNTFAEVTGLSPGVTYYFKVF 978
+T+ W+PP + ++ Y + + G+HG+ + T V L P Y F++
Sbjct: 540 SITLSWSPPRQESIIKYEL----LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLA 595
Query: 979 AVS-HGRES-KPLTAQQTTKLD---APTNLQFVNETDSTVLVRWTPP-----RAQITGY- 1027
A S G + P+ Q+T + P +++ V+ + +LV W PP + GY
Sbjct: 596 ARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYS 655
Query: 1028 -RLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-T 1084
R + +P++ N + P+ ++ L L+ ++Y ++ VA P+++ V T
Sbjct: 656 VRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRT 715
Query: 1085 LQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEA--PREV- 1131
+ S PP E + T I + W +PAP G+++ +G EA P +
Sbjct: 716 DEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIK 775
Query: 1132 ----------TSDSG--SIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSP 1176
T D+ +V++ L P Y T+ DG +V L
Sbjct: 776 DVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGR 835
Query: 1177 PTNLHLEANPDTGVLTVSWE--RSTTPD-ITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
PT L ++ P+ G L WE T D + GYR+ + +LE D+ + +
Sbjct: 836 PT-LSVQQTPE-GSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTAS 893
Query: 1234 FDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
+ + ++ + + ++ V P P N T+ + W PP
Sbjct: 894 GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPP 953
Query: 1291 PSIDLTNFLVRYSPV---------KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
+ +V+Y+ E ++ + ++NA+ L L P T Y + V +
Sbjct: 954 VPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAH 1013
Query: 1342 YEQHE---STPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAP--RATITGYRIRHH-- 1393
+ S P+R R SP I S + W P + T Y+I+++
Sbjct: 1014 TRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGL 1073
Query: 1394 PEHFSGRPREDRV----PHSRNSITLTN 1417
GR + + PH+ + LTN
Sbjct: 1074 TLDVDGRTTKKLITHLKPHTFYNFVLTN 1101
Score = 100 bits (250), Expect = 1e-20
Identities = 188/800 (23%), Positives = 302/800 (37%), Gaps = 129/800 (16%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRW--KEATIPGHLNSYTIKGLKPGVV 676
T + S I W++ P +S Y++ ++ K+ G + KE Y+I GL P
Sbjct: 341 TENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSE 397
Query: 677 YEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSF 736
YE + ++ G + + T TGE P S + ++A++
Sbjct: 398 YEIWVSAVNSIGQGPPSE------------SVVTRTGEQAPAS--APRNVQARMLSATTM 443
Query: 737 VVSW---VSASDTVSGFRVEYELSEE---GDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
+V W V + + G+RV Y + E G+ ++ S T+V LL Y V V
Sbjct: 444 IVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVG--SLLEDETYTVRV 501
Query: 791 YQISEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP-QAPITGYRIVYS 846
+ G+ L I +Q P P + + +TSI + WS P Q I Y +++
Sbjct: 502 LAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFR 561
Query: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN--QESTPVVIQQETTGTPRS 904
G T S + DL+P +Y + A TPVV Q+ P +
Sbjct: 562 EGDHGREVGRTFDPT-TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSA 620
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRN 959
P+D++ V V + + W PP A+ GY V P+ G P +
Sbjct: 621 ----PPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPL------GSEDPEPK- 669
Query: 960 TFAEVTGLSPGVTY----------YFKVFAVSH-----GRESKPLTAQQTTKLDAPT--- 1001
EV G+ P T +++ V+H G ES P+ + T D P+
Sbjct: 670 ---EVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVR--TDEDVPSAPP 724
Query: 1002 ---NLQFVNETDSTVLVRWTPP---RAQITGYRL----TVGLTRRGQPRQYNVGPSVSKY 1051
+ +N T VL R P QI GY++ G RG PR +V + +++
Sbjct: 725 RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQW 784
Query: 1052 P----------LRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI--PPYNTE 1097
+ NLQP + Y++++ A +KG+ K V T G+ + P + +
Sbjct: 785 ETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVT---KGAVLGRPTLSVQ 841
Query: 1098 VT-ETTIVITWTPAPRIGFK--LGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEY 1149
T E +++ W P LG R G E A E SG+ G Y
Sbjct: 842 QTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATY 901
Query: 1150 VYTIQV-LRDGQERDAPIVNKVV--TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY 1206
V+ + R G +A V + TP P L N G + + W + G
Sbjct: 902 VFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGA 961
Query: 1207 RITTTPT---NGQQGNSLEEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
+ T G G + E + A +++ T L P Y++ V + P
Sbjct: 962 IVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQV-RAHTRRGPGP 1020
Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT-NFLVRY---SPVKNEEDVAEL 1314
S P V T LR + P +V S+ L+ F Y +P K + + L
Sbjct: 1021 FS----PPVRYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTL 1075
Query: 1315 SISPSDNAVVLTNLLPGTEY 1334
+ ++T+L P T Y
Sbjct: 1076 DVDGRTTKKLITHLKPHTFY 1095
Score = 48.1 bits (113), Expect = 1e-04
Identities = 53/251 (21%), Positives = 103/251 (41%), Gaps = 28/251 (11%)
Query: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD----TLTSRPA 1714
+ G V +T PM + + + M + + + +KD T + +
Sbjct: 257 MPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSS 316
Query: 1715 QGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVPANGQTPI 1767
GV+ + ++ P VT+ T T+ITI+W + + ++ + ++ + P
Sbjct: 317 LGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPY 376
Query: 1768 QRTIKPDVRS--YTITGLQPGTDYKIYLYTLNDNARSSP-----VVIDASTAIDAPSNLR 1820
Q IK D+ + Y+I GL P ++Y+I++ +N + P AP N++
Sbjct: 377 Q--IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQ 434
Query: 1821 FLATTPNSLLVSWQ---PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA---TITGLE 1874
+ +++V W+ P I GY + Y P V + V ++ T+ L
Sbjct: 435 ARMLSATTMIVQWEEPVEPNGLIRGYRVYYTM--EPEHPVGNWQKHNVDDSLLTTVGSLL 492
Query: 1875 PGTEYTIYVIA 1885
YT+ V+A
Sbjct: 493 EDETYTVRVLA 503
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 142 bits (359), Expect = 3e-33
Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)
Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Y C TD S G+ W T N T G E TQ GN++G+PC PF
Sbjct: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421
+ G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC D TV+ GGNS G LC
Sbjct: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
Query: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
FPF + Y+ CTSEGR D WC TT N+D+D+K+GFCP +AAHE
Sbjct: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
Score = 136 bits (342), Expect = 3e-31
Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)
Query: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395
LG GV V T GN++G C PF + GR++ +CTT+GR DG WCSTT+NY+ D
Sbjct: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
Query: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455
++ FC + T+ GN++G C FPF++ +Y+ CT++GR D +WC TT NYD D
Sbjct: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
Query: 456 QKFGFCPMAAHEEICTTN 473
+ FGFCP A + N
Sbjct: 324 KLFGFCPTRADSTVMGGN 341
Score = 86.3 bits (212), Expect = 3e-16
Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)
Query: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449
++++ D+ +S V+V TR GN++GA CHFPF++ +Y+ CT++GR D + WC TT
Sbjct: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
Query: 450 QNYDADQKFGFCP 462
NYD D +FGFCP
Sbjct: 260 ANYDTDDRFGFCP 272
Score = 83.6 bits (205), Expect = 2e-15
Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Q Y C TD S G +W T N G C A + GGNS GE C
Sbjct: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 142 bits (359), Expect = 3e-33
Identities = 196/828 (23%), Positives = 335/828 (40%), Gaps = 91/828 (10%)
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA-- 1110
L N+ ++ YT ++ G E+ V +P I TE T T++ +TW
Sbjct: 287 LSNVVRSANYTCVAISSLGMIEATAQVTVKALPKP--PIDLVVTETTATSVTLTWDSGNS 344
Query: 1111 -PRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERDAPI 1166
P + + R + G E P + + + GL+P EY + + + G+ +
Sbjct: 345 EPVTYYGIQYRAA-GTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403
Query: 1167 VNKVV---TPLSPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSL 1221
V P SPP + + +L V WE P+ + GYR+ TP + + N+
Sbjct: 404 VRARTGEQAPSSPPRRVQARMLSASTML-VQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW 462
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPAVPP-PTDLRFTN 1277
+ T +L PG+ Y++ V V D S I VP P D +
Sbjct: 463 HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522
Query: 1278 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
++++W PP + + + Y ++E+ +++ P+ ++ L +L P T Y
Sbjct: 523 ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581
Query: 1338 VSSVYEQHES--TPL---RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRA-----TITG 1387
+++ + TP R Q T P + + + + V W+ P A IT
Sbjct: 582 LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641
Query: 1388 YRIRHHPEHFSGRPRE--DRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLI 1441
Y + + R R D + +S L L TEY V + A G E SP+L+
Sbjct: 642 YSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701
Query: 1442 GQQSTV-SDVPRDLEVVAATPTSLLISWDAPAVT-----VRYYRITY-----GETGGNSP 1490
V S PR +EV T++ + W P + +R Y++TY GE G
Sbjct: 702 RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPI 761
Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQV 1550
+Q+ + ++ T TISGL P Y++TV A T +GD A SKP + + M +
Sbjct: 762 IQDVMLAEAQET-TISGLTPETTYSVTVAAYTTKGDG-ARSKPKIVTTTGAVPGRPTMMI 819
Query: 1551 TDVQDNSISVKWLPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1607
+ N+ ++W P + GYR+ + P T G D T+ GL
Sbjct: 820 STTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTT 878
Query: 1608 YVVSVYAQNPSGESQPLVQTAVT--TIPA--PTDLKFTQVTPTSLSAQWTPP-----NVQ 1658
Y+ + A+N +G + + T +P+ P +L T +T ++ W PP N +
Sbjct: 879 YIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGR 938
Query: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1718
+ Y V +E+ + ++GL T Y++ V A TS+ + +
Sbjct: 939 IISYTVVF---RDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRA----WTSKGSGPLS 991
Query: 1719 TTLENVSPP------RRARVTDATETTITISWRTKTETITGFQVDAVP----ANGQTPIQ 1768
++++ + P + RV A +T++ +SW + AVP NGQ
Sbjct: 992 PSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE-----VPDSYKSAVPFKILYNGQ---- 1042
Query: 1769 RTIKPDVRSY--TITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1814
+++ D S I LQP T+Y L +A ++ TA D
Sbjct: 1043 -SVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPD 1089
Score = 129 bits (325), Expect = 3e-29
Identities = 162/633 (25%), Positives = 263/633 (41%), Gaps = 67/633 (10%)
Query: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1364
EE E + N + L+N++ Y V++SS+ E ++ K +D +
Sbjct: 270 EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325
Query: 1365 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1422
++ TA S T+ W + + +T Y I++ G +E D V +R SI L+P +
Sbjct: 326 VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383
Query: 1423 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1474
EY ++A+N P G+Q+ S PR ++ + +++L+ W+ P
Sbjct: 384 EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442
Query: 1475 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
VR YR+ Y P + T G +T + L PG+ Y++ V A T GD P S
Sbjct: 443 LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500
Query: 1531 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1586
+I +T+ P+Q Q D I + WL P + Y +
Sbjct: 501 P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557
Query: 1587 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQ--TAVTTIPAPTD-LKFT 1641
T P + T+E L+P Y + A++ G P ++ TA +T AP +
Sbjct: 558 KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616
Query: 1642 QVTPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
+ T++ W PP N +T Y V E G ++ + SS + GL
Sbjct: 617 SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676
Query: 1695 ATKYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET- 1750
T+Y V V A D + V V T E+V PPR+ V T + + W+ +
Sbjct: 677 WTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSK 736
Query: 1751 ----ITGFQVDAVPANGQTP-----IQRTIKPDVRSYTITGLQPGTDYKIYLY---TLND 1798
I G+QV V P IQ + + + TI+GL P T Y + + T D
Sbjct: 737 QHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGD 796
Query: 1799 NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYEKPGSPPR 1855
ARS P ++ + A+ + T N+ L+ W PP+ + GY ++Y +
Sbjct: 797 GARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP 856
Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
+ + T+TGL GT Y I+ +A KN
Sbjct: 857 NTIDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 887
Score = 127 bits (318), Expect = 2e-28
Identities = 191/813 (23%), Positives = 325/813 (39%), Gaps = 81/813 (9%)
Query: 1087 PGSSIPPYNTEV-----TETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
P SIPP + EV T V P P + + +G + E+ + +S
Sbjct: 232 PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED---EMPVGRNVLELS 288
Query: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
+ Y E A + K + PP +L + T V T++W+ +
Sbjct: 289 NVVRSANYTCVAISSLGMIEATAQVTVKALP--KPPIDLVVTETTATSV-TLTWDSGNSE 345
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-----DKES 1256
+T Y I G +G +EV + + LSP EY V V E+
Sbjct: 346 PVTYYGIQYRAA-GTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403
Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKNEEDVAEL 1314
V PP ++ + TM V W PP P+ + + V Y+P A
Sbjct: 404 VRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWH 463
Query: 1315 SISPSDNAVVLT--NLLPGTEY---VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
+ +D ++ T +LLPG Y V++ ++V + S ++ + + G+ + +++
Sbjct: 464 KHN-TDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522
Query: 1370 TANS-FTVHWIAP-RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
+++ + W+ P + I Y + + + + + +S TL +L P T Y
Sbjct: 523 ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581
Query: 1428 IVALNGREE---SPLLIGQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----Y 1477
+ A + +P + + QST S P+ + V+ T++ +SW P R
Sbjct: 582 LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641
Query: 1478 YRITY----GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
Y + Y GE G V + S+ + GL+ +Y + V A T G P SS P
Sbjct: 642 YSVAYEAVDGEDRGRHVVDG--ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESS-P 698
Query: 1534 ISINYRTEIDKPS----QMQVTDVQDNSISVKW---LPSSS--PVTGYRVTTTP-KNGPG 1583
+ + RT+ D PS +++V + ++ V W +PS + GY+VT +NG
Sbjct: 699 VLV--RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756
Query: 1584 ---PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLVQTAVTTIPAPTD 1637
P + E TI GL P Y V+V A G+ S+P + T +P
Sbjct: 757 RGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPT 816
Query: 1638 LKFTQVTPTSLSAQWTPPNV---QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
+ + + QW PP +L GYR++ ++ P I+ D V+GL
Sbjct: 817 MMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHK 875
Query: 1695 ATKYEVSVYALKDTLTSRPAQGVVTTLENVSP--PRRARVTDATETTITISW-----RTK 1747
T Y + A + + T E++ P+ VT T +T ++W +
Sbjct: 876 GTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAER 935
Query: 1748 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPV 1805
I + V N Q +Q I D R +T+TGL+P T Y K+ +T + SP
Sbjct: 936 NGRIISYTVVFRDINSQQELQN-ITTDTR-FTLTGLKPDTTYDIKVRAWTSKGSGPLSPS 993
Query: 1806 VIDASTAIDA--PSNLRFLATTPNSLLVSWQPP 1836
+ + ++ N R A S+L+SW+ P
Sbjct: 994 IQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVP 1026
Score = 121 bits (303), Expect = 9e-27
Identities = 157/680 (23%), Positives = 264/680 (38%), Gaps = 71/680 (10%)
Query: 1264 IPAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
+ A+P PP DL T ++ +TW S +T + ++Y E E+ +
Sbjct: 315 VKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD-GVATTR 373
Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITANSFTVH 1377
+ L P +EY V +V P R +TG +P+ + ++A++ V
Sbjct: 374 YSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQ 433
Query: 1378 WIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYVVSIVAL 1431
W P + GYR+ + P+ S RP H+ ++ LT +L PG Y + ++A
Sbjct: 434 WEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAF 491
Query: 1432 NGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRITYGETG 1486
+ P + + Q V P D + + T + +SW P + Y + Y
Sbjct: 492 TAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAE 551
Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
+ T + S+ T+ LKP Y + + R D +I RT PS
Sbjct: 552 DEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEARTAQSTPS 607
Query: 1547 ----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG--PDQT 1595
++ + ++ V W+P + +T Y V +G + G + +
Sbjct: 608 APPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHS 667
Query: 1596 EMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTTIPA--PTDLKFTQVTPTSLSA 1650
+ GL+ EY V V A P ES P++ +P+ P ++ + T++
Sbjct: 668 SWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHV 727
Query: 1651 QWTPP-----NVQLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEV 1700
W P + Q+ GY+V E P ++++ LA ++ +SGL T Y V
Sbjct: 728 YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA-EAQETTISGLTPETTYSV 786
Query: 1701 SVYALK---DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGF 1754
+V A D S+P +VTT V ++ T + W E + G+
Sbjct: 787 TVAAYTTKGDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGY 844
Query: 1755 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1814
++ A+ P D + +T+TGL GT Y L N + T D
Sbjct: 845 RLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPED 904
Query: 1815 APS----NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGV 1865
PS NL T ++ ++W PP RI Y + + S + +
Sbjct: 905 LPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTD 961
Query: 1866 TEATITGLEPGTEYTIYVIA 1885
T T+TGL+P T Y I V A
Sbjct: 962 TRFTLTGLKPDTTYDIKVRA 981
Score = 117 bits (294), Expect = 1e-25
Identities = 196/843 (23%), Positives = 326/843 (38%), Gaps = 90/843 (10%)
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
A +T D P + + + V + T V I E T +P P DL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328
Query: 917 EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
E T VT+ W S VT Y + G Q + T + GLSP Y F
Sbjct: 329 ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387
Query: 976 KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
+V AV+ G S+ + A+ + P +Q + ST+LV+W P P + GY
Sbjct: 388 RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447
Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
R+ R P ++N + + +L P Y++ ++A + P + +
Sbjct: 448 RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506
Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
Q G P + EV ++T I ++W P+ I ++L ++ + +VT D + S
Sbjct: 507 TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566
Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
+ L P Y + + D G P + TP +PP + + T V V
Sbjct: 567 YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625
Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
SW S IT Y + +G+ +G + + + + SS L EY V V
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685
Query: 1249 TVKD---DKESVPI---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPSI---DLTNF 1298
D ES P+ +D +P+ PP + + + V W P PS + +
Sbjct: 686 AHTDVGPGPESSPVLVRTDEDVPS-GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744
Query: 1299 LVRYSPVKNEED-----VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
V Y ++N E + ++ ++ + + + L P T Y V+V++ + + R
Sbjct: 745 QVTYVRLENGEPRGLPIIQDVMLAEAQETTI-SGLTPETTYSVTVAAYTTKGDG----AR 799
Query: 1354 QKTGLDSPTG-------IDFSDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPRE 1403
K + + TG + S N+ + W P+ + GYR+++ RP
Sbjct: 800 SKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD-EARPNT 858
Query: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAA 1459
T+T L GT Y+ + A N G E + + S P++L V
Sbjct: 859 IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGL 918
Query: 1460 TPTSLLISWDAPAVTVR-----YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
T ++ ++WD P + R Y + + + +Q T + + T++GLKP Y
Sbjct: 919 TTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT---TDTRFTLTGLKPDTTY 975
Query: 1515 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-LPSSSPVTGYR 1573
I V A T +G P S S E +V S+ + W +P S Y+
Sbjct: 976 DIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDS-----YK 1030
Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY-VVSVYAQNPSGESQPLV--QTAVT 1630
K + G ++ I LQP EY V + + +G Q LV +TA
Sbjct: 1031 SAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPD 1089
Query: 1631 TIP 1633
+P
Sbjct: 1090 LLP 1092
Score = 107 bits (267), Expect = 1e-22
Identities = 162/729 (22%), Positives = 270/729 (37%), Gaps = 73/729 (10%)
Query: 990 TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
TAQ T K P +L T ++V + W ++ +T Y + P Q G
Sbjct: 310 TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FTTLQPGSSIPPYNTE---VTETT 1102
+ ++Y + L P SEY ++A+ P + V T + S PP + ++ +T
Sbjct: 370 ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429
Query: 1103 IVITWTPAPR-----IGFKLGVRPS--QGGEAPREVTSDSGSI-VVSGLTPGVEY---VY 1151
+++ W P G+++ P + A + +D+G + V L PG+ Y V
Sbjct: 430 MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
+ DG V + P + E DT + +SW I Y +
Sbjct: 490 AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV---PISDTIIPAVP 1268
+ + +V SS T ++L P Y + D V I + P
Sbjct: 549 AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTP 606
Query: 1269 --PPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVAEL--SISPSD 1320
PP + ++G T+RV+W PPP+ +T + V Y V E+ + IS
Sbjct: 607 SAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREH 666
Query: 1321 NAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS--PTGIDFSDITANSFT 1375
++ L L TEY V V + V ES+P+ R + S P ++ + + +
Sbjct: 667 SSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVH 726
Query: 1376 VHWIAP-----RATITGYRIRHHPEHFSGRPR-----EDRVPHSRNSITLTNLTPGTEYV 1425
V+W P I GY++ + +G PR +D + T++ LTP T Y
Sbjct: 727 VYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYS 785
Query: 1426 VSIVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV---TVRYY 1478
V++ A +G P ++ V P + A T+LL W P + Y
Sbjct: 786 VTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALL-QWHPPKELPGELLGY 844
Query: 1479 RITYGETGGNSPVQEFTVPGSKSTA--TISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
R+ Y P T+ K T++GL G Y + A G K I
Sbjct: 845 RLQYCRADEARP---NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRT 901
Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
P + VT + ++ + W P + + Y V N + T
Sbjct: 902 PEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT- 960
Query: 1592 PDQTEMTIEGLQPTVEYVVSV--YAQNPSGESQPLVQTAVTTIPA--PTDLKFTQVTPTS 1647
T T+ GL+P Y + V + SG P +Q+ + + + TS
Sbjct: 961 --DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTS 1018
Query: 1648 LSAQWTPPN 1656
+ W P+
Sbjct: 1019 VLLSWEVPD 1027
Score = 86.7 bits (213), Expect = 2e-16
Identities = 125/566 (22%), Positives = 223/566 (39%), Gaps = 67/566 (11%)
Query: 628 IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
+ W P I Y ++ W ++ + K P +SYT++ LKP +Y QL +
Sbjct: 530 LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
G T T+ STP + P ++ S T + VSWV
Sbjct: 588 MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633
Query: 742 SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
S + ++ + V YE + D +++ + +S ++ L +Y V V ++ G
Sbjct: 634 SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693
Query: 798 -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
E S +L + P PP V+ ++ T++ V W S+ I GY++ Y
Sbjct: 694 PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753
Query: 851 GSSTELNLPE-----TANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTP 902
G L + + A T+S L P Y++T+ A + S P ++ TTG
Sbjct: 754 GEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIV--TTTG-- 809
Query: 903 RSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGEHGQRLPISR 958
VP R + T + ++ W PP+ + GYR+ + +
Sbjct: 810 ---AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDD 865
Query: 959 NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQFVNETDSTVL 1014
F VTGL G TY F++ A + + + T D P+ NL T ST
Sbjct: 866 QHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTE 924
Query: 1015 VRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
+ W PP A+ G ++ + R Q N+ + +++ L L+P + Y + + A
Sbjct: 925 LAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTTYDIKVRAWT 983
Query: 1071 GNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
P + + + P + N V +T+++++W + + G++
Sbjct: 984 SKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS 1043
Query: 1128 PREVTSDSGSIVVSGLTPGVEYVYTI 1153
EV S +++ L P EY + +
Sbjct: 1044 V-EVDGHSMRKLIADLQPNTEYSFVL 1068
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,787,178
Number of Sequences: 37866
Number of extensions: 5670609
Number of successful extensions: 23036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 253
Number of HSP's that attempted gapping in prelim test: 11231
Number of HSP's gapped (non-prelim): 3505
length of query: 2296
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2178
effective length of database: 13,779,330
effective search space: 30011380740
effective search space used: 30011380740
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.