Search of human proteins with 47132549

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo
sapiens]
         (2176 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]     4534   0.0  
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]     3936   0.0  
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]     3543   0.0  
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]     3543   0.0  
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]     2989   0.0  
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]     2989   0.0  
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]     1440   0.0  
gi|153946395 tenascin C precursor [Homo sapiens]                      364   e-100
gi|157384973 tenascin R [Homo sapiens]                                356   2e-97
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...   342   3e-93
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]           306   1e-82
gi|62988324 tenascin N [Homo sapiens]                                 300   1e-80
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...   281   6e-75
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         224   5e-58
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]                201   8e-51
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                159   3e-38
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...   152   3e-36
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...   152   5e-36
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...   152   5e-36
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...   150   1e-35
gi|110349719 titin isoform N2-A [Homo sapiens]                        149   3e-35
gi|110349717 titin isoform novex-2 [Homo sapiens]                     149   3e-35
gi|110349713 titin isoform novex-1 [Homo sapiens]                     149   3e-35
gi|110349715 titin isoform N2-B [Homo sapiens]                        149   3e-35
gi|222352127 sidekick 2 [Homo sapiens]                                148   7e-35
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]      146   2e-34
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...   146   2e-34
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...   145   3e-34
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo...   145   3e-34
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ...   143   2e-33

>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
          Length = 2176

 Score = 4534 bits (11760), Expect = 0.0
 Identities = 2176/2176 (100%), Positives = 2176/2176 (100%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
            SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680

Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
            APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI
Sbjct: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740

Query: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
            TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA
Sbjct: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800

Query: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860
            RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR
Sbjct: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860

Query: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTS 1920
            PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTS
Sbjct: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTS 1920

Query: 1921 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 1980
            EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV
Sbjct: 1921 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 1980

Query: 1981 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2040
            GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW
Sbjct: 1981 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2040

Query: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2100
            CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK
Sbjct: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2100

Query: 2101 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2160
            EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE
Sbjct: 2101 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2160

Query: 2161 CFMPLDVQADREDSRE 2176
            CFMPLDVQADREDSRE
Sbjct: 2161 CFMPLDVQADREDSRE 2176


>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
          Length = 2296

 Score = 3936 bits (10207), Expect = 0.0
 Identities = 1901/1903 (99%), Positives = 1902/1903 (99%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
            SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680

Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
            APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI
Sbjct: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740

Query: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
            TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA
Sbjct: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800

Query: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860
            RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR
Sbjct: 1801 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1860

Query: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQ 1903
            PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT +
Sbjct: 1861 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 1903



 Score = 1071 bits (2769), Expect = 0.0
 Identities = 636/1587 (40%), Positives = 863/1587 (54%), Gaps = 127/1587 (8%)

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814

Query: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868

Query: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928

Query: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988

Query: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V      G   
Sbjct: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035

Query: 952  QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
            +  P   N    V+      L P   Y   + A+   +ES   T   TT     +   + 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
             E T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151

Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
            ++  ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
               P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAV 1267

Query: 1175 SPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
             PPT+L      PDT  + V+W    + D+T + +  +P   ++ +  E  +    ++  
Sbjct: 1268 PPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVV 1324

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
              NL PG EY VSV +V +  ES P+       +  PT + F++I  ++  V W  P + 
Sbjct: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT 1384

Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
             +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  L G+
Sbjct: 1385 -ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443

Query: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
            Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S+++ 
Sbjct: 1444 QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503

Query: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWD 1469
            T++ L PG +Y +++ A+ GR +SP      S    T  D P  ++V      S+ + W 
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1563

Query: 1470 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
              +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G+S  
Sbjct: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES-- 1621

Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
              +P+     T I  P+ ++ T V   S+S +W P +  +TGYRV  TPK   GP K   
Sbjct: 1622 --QPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1679

Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTTIPAPTDLKFTQVTPTS 1647
              PD + + + GL    +Y VSVYA   +  S+P   V T +  +  P   + T  T T+
Sbjct: 1680 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1739

Query: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
            ++  W      +TG++V   P     P++   + PD  S  ++GL   T Y++ +Y L D
Sbjct: 1740 ITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLND 1798

Query: 1708 TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQTP 1766
               S P   V+     +  P   R    T  ++ +SW+     ITG+ +    P +    
Sbjct: 1799 NARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1856

Query: 1767 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV------------------ID 1808
            +    +P V   TITGL+PGT+Y IY+  L +N +S P++                  + 
Sbjct: 1857 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLH 1916

Query: 1809 ASTAIDAPSNLR---FLA----TTPNSLLVSWQPPRARITGYIIKYEKPG----SPPREV 1857
                +D PS ++   F+      T N + +     +    G  + +E+ G    +PP   
Sbjct: 1917 GPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTA 1976

Query: 1858 VP---RPRP---GVTEATITGLEP--GTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQT 1909
             P   RPRP    V E    G  P    +Y +Y      N  +        TGQEALSQT
Sbjct: 1977 TPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAS-------TGQEALSQT 2029

Query: 1910 TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 1969
            TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ
Sbjct: 2030 TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2089

Query: 1970 RHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFG 2029
            RHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFG
Sbjct: 2090 RHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFG 2149

Query: 2030 SGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDG 2089
            SGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDG
Sbjct: 2150 SGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDG 2209

Query: 2090 KTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQ 2149
            KTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQ
Sbjct: 2210 KTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQ 2269

Query: 2150 RTNTNVNCPIECFMPLDVQADREDSRE 2176
            RTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2270 RTNTNVNCPIECFMPLDVQADREDSRE 2296



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2109 CTCFGGQRG 2117
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2229 CTCFGGQRG 2237



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2118 WRC 2120
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237

Query: 597  WHC 599
            W C
Sbjct: 2238 WRC 2240



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2118 WRCD 2121
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237

Query: 268  WKCE 271
            W+C+
Sbjct: 2238 WRCD 2241



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2216 EQWQKEYLGAICSCTCFGGQRG 2237



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2145 QR 2146
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264

Query: 106  YR 107
             R
Sbjct: 2265 QR 2266



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192



 Score = 39.3 bits (90), Expect = 0.043
 Identities = 39/173 (22%), Positives = 68/173 (39%), Gaps = 31/173 (17%)

Query: 1826 PNSLLVSWQPPR-ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1884
            PNS  + W  P+ + I+ YI+++    S  R         +   TI GL+PG  Y   +I
Sbjct: 623  PNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLI 682

Query: 1885 ALKN-------------NQKSEPLIGRKKTGQ-----------EALSQTT-----ISWAP 1915
            +++                 S P+     TG+           E++++ T     +SW  
Sbjct: 683  SIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS 742

Query: 1916 FQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 1967
              DT S + +        +EP    +P T+TS  +  L  G  Y + V  + +
Sbjct: 743  ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795


>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
          Length = 2355

 Score = 3543 bits (9186), Expect = 0.0
 Identities = 1737/1986 (87%), Positives = 1793/1986 (90%), Gaps = 21/1986 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
            SQPLVQTAVT I  P  L FT V   S+   W  P  Q++ YRV  +  E    + E+  
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678

Query: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
            APD    +  + GL   ++Y VSV AL D + S+P  G  +T   +  P   + T  T T
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736

Query: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
            +++  W      +TG++V   P     P++   + PD  S  ++GL   T Y++ +Y L 
Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796

Query: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855
            D   S P   V+     +  P   R    T  ++ +SW+     ITG+ +    P +   
Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855

Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQ-----TT 1910
             +    +P V   TITGL+PGT+Y IY+  L +N +S P++    T  +A S      TT
Sbjct: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 1915

Query: 1911 -----ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEA 1964
                 +SW P +   + YII     G+    +  R     T AT+TGL  G  Y I V A
Sbjct: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975

Query: 1965 LKDQQR 1970
            LK+ Q+
Sbjct: 1976 LKNNQK 1981



 Score = 1324 bits (3427), Expect = 0.0
 Identities = 771/1637 (47%), Positives = 967/1637 (59%), Gaps = 168/1637 (10%)

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814

Query: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868

Query: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928

Query: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988

Query: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V      G   
Sbjct: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035

Query: 952  QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
            +  P   N    V+      L P   Y   + A+   +ES   T   TT     +   + 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
             E T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151

Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
            ++  ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
               P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAV 1267

Query: 1175 SPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
             PPT+L      PDT  + V+W    + D+T + +  +P   ++ +  E  +    ++  
Sbjct: 1268 PPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVV 1324

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
              NL PG EY VSV +V +  ES P+       +  PT + F++I  ++  V W  P + 
Sbjct: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT 1384

Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
             +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  L G+
Sbjct: 1385 -ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443

Query: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
            Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S+++ 
Sbjct: 1444 QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503

Query: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWD 1469
            T++ L PG +Y +++ A+ GR +SP      S    T  D P  ++V      S+ + W 
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1563

Query: 1470 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
              +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G+S  
Sbjct: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES-- 1621

Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGPTKTK 1588
              +P+     T ID+P  +  TDV  +SI + W      V+ YRVT ++P++G       
Sbjct: 1622 --QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1679

Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSL 1648
              G + T   ++GL+P  EY VSV A +   ESQPL+ T  T IPAPTDLKFTQVTPTSL
Sbjct: 1680 PDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSL 1738

Query: 1649 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
            SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT
Sbjct: 1739 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1798

Query: 1709 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
            LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ
Sbjct: 1799 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1858

Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA----------PSN 1818
            RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA          P++
Sbjct: 1859 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1918

Query: 1819 LRFLATTPNSLLVSW--------QPPR------------ARITG---------YIIKYE- 1848
            L      P + +  +         PPR            A ITG         Y+I  + 
Sbjct: 1919 LLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978

Query: 1849 ----------KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV----------IALKN 1888
                      K      ++V  P P +    I  +    + T +V          I L  
Sbjct: 1979 NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038

Query: 1889 NQKSEPLIGRK-----------------------------KTGQEALSQTTISWAPFQDT 1919
                +P +G++                               GQEALSQTTISWAPFQDT
Sbjct: 2039 TSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDT 2098

Query: 1920 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 1979
            SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT
Sbjct: 2099 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 2158

Query: 1980 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2039
            VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR
Sbjct: 2159 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2218

Query: 2040 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2099
            WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ
Sbjct: 2219 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2278

Query: 2100 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2159
            KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI
Sbjct: 2279 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2338

Query: 2160 ECFMPLDVQADREDSRE 2176
            ECFMPLDVQADREDSRE
Sbjct: 2339 ECFMPLDVQADREDSRE 2355



 Score =  462 bits (1189), Expect = e-129
 Identities = 346/1230 (28%), Positives = 564/1230 (45%), Gaps = 79/1230 (6%)

Query: 829  VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
            ++W+ PQ + I+ Y + + P    G   E  +P   NS T+  L+PGV Y   + ++++ 
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 886  -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
             +QE T       +T TP +    +     F           E+T     + W      V
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747

Query: 935  TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
            +G+RV+   ++  G+  Q L + S  T   +  L PG  Y   V+ +S  G +S  L+  
Sbjct: 748  SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
            QTT  DAP +       D++++VRW+ P+A ITGYR+    +  G   + N+  + +   
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
            L +LQP  +Y +++ A++ NQES P      TT  P S   P        EVT+  + I 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
            WTP      G+++ V P    G    R   S +    V+GL+PGV Y + +  +  G+E 
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985

Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
              P+  +  T L  PTNL      D+ VL V W   T P   ITGYR+T   T  ++G  
Sbjct: 986  SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP----PPTDLRFT 1276
             +  V    S     NL P  EY VS+  +K ++ES   +       P    PP +   T
Sbjct: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---T 1096

Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
             +   T+ +TW P P I    F +   P +  E  A   ++    ++V++ L PG EYV 
Sbjct: 1097 EVTETTIVITWTPAPRI---GFKLGVRPSQGGE--APREVTSDSGSIVVSGLTPGVEYVY 1151

Query: 1337 SVSSVYE-QHESTPLRGRQKTGLDSPTGIDF-SDITANSFTVHWIAPRAT---ITGYRIR 1391
            ++  + + Q    P+  +  T L  PT +   ++      TV W   R+T   ITGYRI 
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW--ERSTTPDITGYRIT 1209

Query: 1392 HHPEHFS-GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
              P +   G   E+ V   ++S T  NL+PG EY VS+  +   +ES  +          
Sbjct: 1210 TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP 1269

Query: 1451 PRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
            P DL      P ++ ++W   P++ +  + + Y        V E ++  S +   ++ L 
Sbjct: 1270 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1329

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
            PG +Y ++V +V  + +S     P+    +T +D P+ +  +D+  NS +V W+   + +
Sbjct: 1330 PGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI 1385

Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
            TGYR+   P++  G  +       +  +T+  L P  EYVVS+ A N   ES  L+    
Sbjct: 1386 TGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445

Query: 1630 TTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1689
            T    P DL+    TPTSL   W  P V +  YR+         P++E  +    S+  +
Sbjct: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505

Query: 1690 SGLMVATKYEVSVYALK----DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745
            SGL     Y ++VYA+        +S+P    +     +  P + +VTD  + +I++ W 
Sbjct: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPIS--INYRTEIDKPSQMQVTDVQDNSISVKWL 1563

Query: 1746 TKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
              +  +TG++V   P NG  P + +T  PD    TI GLQP  +Y + +Y  N +  S P
Sbjct: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623

Query: 1805 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864
            +V  A T ID P  L F     +S+ ++W+ P+ +++ Y + Y  P     E+ P P   
Sbjct: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683

Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA--------LSQTTIS--WA 1914
               A + GL PG+EYT+ V+AL ++ +S+PLIG + T   A        ++ T++S  W 
Sbjct: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1743

Query: 1915 PFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKV 1973
            P     + Y +   P        +  +   S+S  ++GL     Y + V ALKD    + 
Sbjct: 1744 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803

Query: 1974 REEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003
             + VVT   +V+        D+     T+S
Sbjct: 1804 AQGVVTTLENVSPPRRARVTDATETTITIS 1833



 Score =  368 bits (945), Expect = e-101
 Identities = 311/1159 (26%), Positives = 522/1159 (45%), Gaps = 87/1159 (7%)

Query: 607  SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
            SS  P    +TET     +  I W    P+    + L  RP       +E T      S 
Sbjct: 1089 SSIPPYNTEVTET-----TIVITWT---PAPRIGFKLGVRPSQGGEAPREVTSDS--GSI 1138

Query: 667  TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
             + GL PGV Y    I + + G +              P+ +  VT  + P +  +  + 
Sbjct: 1139 VVSGLTPGVEYV-YTIQVLRDGQER-----------DAPIVNKVVTPLSPPTNLHLEANP 1186

Query: 727  SVTEITASSFVVSWV-SASDTVSGFRVEYELSEEGDEPQYLD--LPSTATSVNIPDLLPG 783
                +T     VSW  S +  ++G+R+       G +   L+  + +  +S    +L PG
Sbjct: 1187 DTGVLT-----VSWERSTTPDITGYRIT-TTPTNGQQGNSLEEVVHADQSSCTFDNLSPG 1240

Query: 784  RKYIVNVYQISEDGEQSLILSTSQTTAPDAPP--DPTVDQVDDTSIVVRWSRPQA-PITG 840
             +Y V+VY + +D E   I   S T  P  PP  D     +   ++ V W+ P +  +T 
Sbjct: 1241 LEYNVSVYTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297

Query: 841  YRIVYSP-SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
            + + YSP   E    EL++  + N+V L++L PG +Y +++ +V E  ESTP+  +Q+T 
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357

Query: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISR 958
                   + SP  + F ++T    T+ W  P + +TGYR+   P +  G   + R+P SR
Sbjct: 1358 -------LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410

Query: 959  NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT 1018
            N+   +T L+PG  Y   + A++   ES  L  QQ+T  D P +L+ V  T +++L+ W 
Sbjct: 1411 NSIT-LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1469

Query: 1019 PPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK 1077
             P   +  YR+T G T    P +++ V  S S   +  L+P  +YT+++ A+ G  +SP 
Sbjct: 1470 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529

Query: 1078 ATGVFTTLQPGSSIPPYNTEVTET---TIVITWTPA--PRIGFKLGVRPSQGGEAPREVT 1132
            ++   +         P   +VT+    +I + W P+  P  G+++   P  G    +  T
Sbjct: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589

Query: 1133 S--DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
            +  D   + + GL P VEYV ++       E   P+V   VT +  P  L    + D   
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTNIDRPKGLAF-TDVDVDS 1647

Query: 1191 LTVSWERSTTPDITGYRIT-TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
            + ++WE S    ++ YR+T ++P +G   + L      ++ +     L PG EY VSV  
Sbjct: 1648 IKIAWE-SPQGQVSRYRVTYSSPEDGI--HELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704

Query: 1250 VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
            + DD ES P+  T   A+P PTDL+FT + P ++   W PP ++ LT + VR +P +   
Sbjct: 1705 LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP-NVQLTGYRVRVTPKEKTG 1763

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGIDFS 1367
             + E++++P  ++VV++ L+  T+Y VSV ++ +   S P +G   T   +  P     +
Sbjct: 1764 PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVT 1823

Query: 1368 DITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
            D T  + T+ W     TITG+++   P +    P +  +     S T+T L PGT+Y + 
Sbjct: 1824 DATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882

Query: 1428 IVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
            +  LN    S  ++   ST  D P +L  +A TP SLL+SW  P   +  Y I Y + G 
Sbjct: 1883 LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPG- 1941

Query: 1488 NSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544
             SP +E  VP  +   + ATI+GL+PG +YTI V A+         S+P+    +T+ + 
Sbjct: 1942 -SPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKNN----QKSEPLIGRKKTD-EL 1994

Query: 1545 PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
            P  + +     +   +  +PS+   T +        G G     T+G           QP
Sbjct: 1995 PQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ----------QP 2044

Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1664
            +V   +          + P   T +   P P      Q   +  +  W P     + Y +
Sbjct: 2045 SVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYII 2103

Query: 1665 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
               P        +  +   S+S  ++GL     Y + V ALKD    +  + VVT   +V
Sbjct: 2104 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163

Query: 1725 SPPRRARVTDATETTITIS 1743
            +        D+     T+S
Sbjct: 2164 NEGLNQPTDDSCFDPYTVS 2182



 Score =  126 bits (316), Expect = 3e-28
 Identities = 137/535 (25%), Positives = 216/535 (40%), Gaps = 63/535 (11%)

Query: 600  QPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATI 659
            QPL    S++ P    +  T   P S   QW  P    ++ Y +R  PK   G  KE  +
Sbjct: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL 1770

Query: 660  PGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS 719
                +S  + GL     YE  + +++              T TS P      T E    S
Sbjct: 1771 APDSSSVVVSGLMVATKYEVSVYALKD-------------TLTSRPAQGVVTTLENV--S 1815

Query: 720  PLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPD 779
            P       VT+ T ++  +SW + ++T++GF+V+  +   G  P    +     S  I  
Sbjct: 1816 P--PRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITG 1872

Query: 780  LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
            L PG  Y + +Y ++++   S ++  + +TA DAP +         S++V W  P+A IT
Sbjct: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDA-STAIDAPSNLRFLATTPNSLLVSWQPPRARIT 1931

Query: 840  GYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
            GY I Y     GS     +P     VT   ++ L+PG +Y I + A++ NQ+S P++ ++
Sbjct: 1932 GYIIKYEKP--GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1989

Query: 897  ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV-IPVNLPGEHGQRLP 955
            +T   P+  T+P P +L   E+ DV  T+  TP    VT    D    + LPG  GQ+  
Sbjct: 1990 KTDELPQLVTLPHP-NLHGPEILDVPSTVQKTP---FVTHPGYDTGNGIQLPGTSGQQPS 2045

Query: 956  ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
            + +    E  G                 R + P TA        P       E  S   +
Sbjct: 2046 VGQQMIFEEHGFR---------------RTTPPTTATPIRHRPRPYPPNVGQEALSQTTI 2090

Query: 1016 RWTPPRAQITGYRLT---VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
             W P +   + Y ++   VG     +P Q+ V  + +   L  L   + Y + + A+K  
Sbjct: 2091 SWAPFQ-DTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 2147

Query: 1073 QESPKATGVFTT--------LQP--GSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
            Q       V T          QP   S   PY   V+   +   W      GFKL
Sbjct: 2148 QRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYT--VSHYAVGDEWERMSESGFKL 2200



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2109 CTCFGGQRG 2117
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2288 CTCFGGQRG 2296



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2118 WRC 2120
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296

Query: 597  WHC 599
            W C
Sbjct: 2297 WRC 2299



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2118 WRCD 2121
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296

Query: 268  WKCE 271
            W+C+
Sbjct: 2297 WRCD 2300



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2275 EQWQKEYLGAICSCTCFGGQRG 2296



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2145 QR 2146
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323

Query: 106  YR 107
             R
Sbjct: 2324 QR 2325



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251


>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score = 3543 bits (9186), Expect = 0.0
 Identities = 1737/1986 (87%), Positives = 1793/1986 (90%), Gaps = 21/1986 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
            SQPLVQTAVT I  P  L FT V   S+   W  P  Q++ YRV  +  E    + E+  
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678

Query: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
            APD    +  + GL   ++Y VSV AL D + S+P  G  +T   +  P   + T  T T
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736

Query: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
            +++  W      +TG++V   P     P++   + PD  S  ++GL   T Y++ +Y L 
Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796

Query: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855
            D   S P   V+     +  P   R    T  ++ +SW+     ITG+ +    P +   
Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855

Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQ-----TT 1910
             +    +P V   TITGL+PGT+Y IY+  L +N +S P++    T  +A S      TT
Sbjct: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 1915

Query: 1911 -----ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEA 1964
                 +SW P +   + YII     G+    +  R     T AT+TGL  G  Y I V A
Sbjct: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975

Query: 1965 LKDQQR 1970
            LK+ Q+
Sbjct: 1976 LKNNQK 1981



 Score = 1122 bits (2903), Expect = 0.0
 Identities = 700/1637 (42%), Positives = 900/1637 (54%), Gaps = 193/1637 (11%)

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814

Query: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868

Query: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928

Query: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988

Query: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V      G   
Sbjct: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035

Query: 952  QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
            +  P   N    V+      L P   Y   + A+   +ES   T   TT     +   + 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
             E T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151

Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
            ++  ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
               P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAV 1267

Query: 1175 SPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
             PPT+L      PDT  + V+W    + D+T + +  +P   ++ +  E  +    ++  
Sbjct: 1268 PPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVV 1324

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
              NL PG EY VSV +V +  ES P+       +  PT + F++I  ++  V W  P + 
Sbjct: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT 1384

Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
             +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  L G+
Sbjct: 1385 -ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443

Query: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
            Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S+++ 
Sbjct: 1444 QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503

Query: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWD 1469
            T++ L PG +Y +++ A+ GR +SP      S    T  D P  ++V      S+ + W 
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1563

Query: 1470 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
              +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G+S  
Sbjct: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES-- 1621

Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGPTKTK 1588
              +P+     T ID+P  +  TDV  +SI + W      V+ YRVT ++P++G       
Sbjct: 1622 --QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1679

Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSL 1648
              G + T   ++GL+P  EY VSV A +   ESQPL+ T  T IPAPTDLKFTQVTPTSL
Sbjct: 1680 PDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSL 1738

Query: 1649 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
            SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT
Sbjct: 1739 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1798

Query: 1709 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
            LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ
Sbjct: 1799 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1858

Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
            RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS
Sbjct: 1859 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1918

Query: 1829 LLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
            LLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN
Sbjct: 1919 LLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978

Query: 1889 NQKSEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSAT 1948
            NQKSEPLIGRKKT Q    +T     P  DT   I               ++PGTS    
Sbjct: 1979 NQKSEPLIGRKKTVQ----KTPFVTHPGYDTGNGI---------------QLPGTSGQQP 2019

Query: 1949 LTG----LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQ------PTDDSCFD 1998
              G                      RH+ R     VG    E L+Q      P  D+   
Sbjct: 2020 SVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG---QEALSQTTISWAPFQDT--S 2074

Query: 1999 PYTVSHYAVGDEWERMS-----------------ESGFKLLCQCLGFGSGHFRCDSSRWC 2041
             Y +S + VG + E +                   + + ++ + L     H +       
Sbjct: 2075 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH-KVREEVVT 2133

Query: 2042 HDNGVNYKIGEKWDRQ------------GENGQMMS-------CTCLGNGKGEFKC---- 2078
              N VN  + +  D              G+  + MS       C CLG G G F+C    
Sbjct: 2134 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2193

Query: 2079 ---------------------------------------DPHEATCYDDGKTYHVGEQWQ 2099
                                                   DPHEATCYDDGKTYHVGEQWQ
Sbjct: 2194 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2253

Query: 2100 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2159
            KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI
Sbjct: 2254 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2313

Query: 2160 ECFMPLDVQADREDSRE 2176
            ECFMPLDVQADREDSRE
Sbjct: 2314 ECFMPLDVQADREDSRE 2330



 Score =  462 bits (1189), Expect = e-129
 Identities = 346/1230 (28%), Positives = 564/1230 (45%), Gaps = 79/1230 (6%)

Query: 829  VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
            ++W+ PQ + I+ Y + + P    G   E  +P   NS T+  L+PGV Y   + ++++ 
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 886  -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
             +QE T       +T TP +    +     F           E+T     + W      V
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747

Query: 935  TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
            +G+RV+   ++  G+  Q L + S  T   +  L PG  Y   V+ +S  G +S  L+  
Sbjct: 748  SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
            QTT  DAP +       D++++VRW+ P+A ITGYR+    +  G   + N+  + +   
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
            L +LQP  +Y +++ A++ NQES P      TT  P S   P        EVT+  + I 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
            WTP      G+++ V P    G    R   S +    V+GL+PGV Y + +  +  G+E 
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985

Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
              P+  +  T L  PTNL      D+ VL V W   T P   ITGYR+T   T  ++G  
Sbjct: 986  SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP----PPTDLRFT 1276
             +  V    S     NL P  EY VS+  +K ++ES   +       P    PP +   T
Sbjct: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---T 1096

Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
             +   T+ +TW P P I    F +   P +  E  A   ++    ++V++ L PG EYV 
Sbjct: 1097 EVTETTIVITWTPAPRI---GFKLGVRPSQGGE--APREVTSDSGSIVVSGLTPGVEYVY 1151

Query: 1337 SVSSVYE-QHESTPLRGRQKTGLDSPTGIDF-SDITANSFTVHWIAPRAT---ITGYRIR 1391
            ++  + + Q    P+  +  T L  PT +   ++      TV W   R+T   ITGYRI 
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW--ERSTTPDITGYRIT 1209

Query: 1392 HHPEHFS-GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
              P +   G   E+ V   ++S T  NL+PG EY VS+  +   +ES  +          
Sbjct: 1210 TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP 1269

Query: 1451 PRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
            P DL      P ++ ++W   P++ +  + + Y        V E ++  S +   ++ L 
Sbjct: 1270 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1329

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
            PG +Y ++V +V  + +S     P+    +T +D P+ +  +D+  NS +V W+   + +
Sbjct: 1330 PGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI 1385

Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
            TGYR+   P++  G  +       +  +T+  L P  EYVVS+ A N   ES  L+    
Sbjct: 1386 TGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445

Query: 1630 TTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1689
            T    P DL+    TPTSL   W  P V +  YR+         P++E  +    S+  +
Sbjct: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505

Query: 1690 SGLMVATKYEVSVYALK----DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745
            SGL     Y ++VYA+        +S+P    +     +  P + +VTD  + +I++ W 
Sbjct: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPIS--INYRTEIDKPSQMQVTDVQDNSISVKWL 1563

Query: 1746 TKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
              +  +TG++V   P NG  P + +T  PD    TI GLQP  +Y + +Y  N +  S P
Sbjct: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623

Query: 1805 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864
            +V  A T ID P  L F     +S+ ++W+ P+ +++ Y + Y  P     E+ P P   
Sbjct: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683

Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA--------LSQTTIS--WA 1914
               A + GL PG+EYT+ V+AL ++ +S+PLIG + T   A        ++ T++S  W 
Sbjct: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1743

Query: 1915 PFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKV 1973
            P     + Y +   P        +  +   S+S  ++GL     Y + V ALKD    + 
Sbjct: 1744 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803

Query: 1974 REEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003
             + VVT   +V+        D+     T+S
Sbjct: 1804 AQGVVTTLENVSPPRRARVTDATETTITIS 1833



 Score =  443 bits (1139), Expect = e-123
 Identities = 355/1215 (29%), Positives = 562/1215 (46%), Gaps = 123/1215 (10%)

Query: 615  FITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPG 674
            F+ ET S   +  ++W  P+ + I+ Y L        G+ ++  +   ++ Y ++ L+P 
Sbjct: 1005 FVNETDS---TVLVRWTPPR-AQITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPA 1059

Query: 675  VVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734
              Y   L++I+  G+QE                S   TG  T   P  +     TE+T +
Sbjct: 1060 SEYTVSLVAIK--GNQE----------------SPKATGVFTTLQPGSSIPPYNTEVTET 1101

Query: 735  SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
            + V++W  A     GF++    S+ G+ P+  ++ S + S+ +  L PG +Y+  + Q+ 
Sbjct: 1102 TIVITWTPAPRI--GFKLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTI-QVL 1156

Query: 795  EDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV-VRWSRPQAP-ITGYRIVYSPS--V 849
             DG++      ++   P +PP    ++   DT ++ V W R   P ITGYRI  +P+   
Sbjct: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT--- 906
            +G+S E  +    +S T  +L PG++YN+++Y V++++ES P+           SDT   
Sbjct: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI-----------SDTIIP 1265

Query: 907  -VPSPRDLQFVEVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
             VP P DL+F  +    + + W PP S  +T + V   PV    E    L IS +  A V
Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISPSDNAVV 1324

Query: 965  -TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
             T L PG  Y   V +V    ES PL  +Q T LD+PT + F + T ++  V W  PRA 
Sbjct: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT 1384

Query: 1024 ITGYRLTVGLTR-RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVF 1082
            ITGYR+        G+PR+  V  S +   L NL P +EY VS+VA+ G +ESP   G  
Sbjct: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1444

Query: 1083 TTLQPGSSIPPYNTEV---TETTIVITW-TPAPRIGFKLGVRPSQGGEAPRE---VTSDS 1135
            +T+    S  P + EV   T T+++I+W  PA  + +        GG +P +   V    
Sbjct: 1445 STV----SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1136 GSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
             +  +SGL PGV+Y  T+  +    D      PI     T +  P+ + +    D  + +
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI-S 1559

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
            V W  S++P +TGYR+TTTP NG  G +  +    DQ+  T + L P +EY VSVY    
Sbjct: 1560 VKWLPSSSP-VTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1617

Query: 1253 DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
              ES P+  T +  +  P  L FT++  D++++ W  P    ++ + V YS    E+ + 
Sbjct: 1618 SGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG-QVSRYRVTYS--SPEDGIH 1674

Query: 1313 ELSISPS--DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
            EL  +P   ++   L  L PG+EY VSV ++++  ES PL G Q T + +PT + F+ +T
Sbjct: 1675 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734

Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
              S +  W  P   +TGYR+R  P+  +G  +E  +    +S+ ++ L   T+Y VS+ A
Sbjct: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1794

Query: 1431 LNGREESPLLIGQQSTVSDV--PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGN 1488
            L     S    G  +T+ +V  PR   V  AT T++ ISW     T+  +++      G 
Sbjct: 1795 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ 1854

Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
            +P+Q    P  +S  TI+GL+PG DY I +Y +       A S P+ I+  T ID PS +
Sbjct: 1855 TPIQRTIKPDVRSY-TITGLQPGTDYKIYLYTLNDN----ARSSPVVIDASTAIDAPSNL 1909

Query: 1549 QVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
            +      NS+ V W P  + +TGY +       P         P  TE TI GL+P  EY
Sbjct: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969

Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPN-VQLTGYRVRVT 1667
             + V A   + +S+PL+             K  Q TP      +   N +QL G      
Sbjct: 1970 TIYVIALKNNQKSEPLIGRK----------KTVQKTPFVTHPGYDTGNGIQLPG------ 2013

Query: 1668 PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPP 1727
                                  SG   +   ++         T+ P     T + +   P
Sbjct: 2014 ---------------------TSGQQPSVGQQMIFEEHGFRRTTPPT--TATPIRHRPRP 2050

Query: 1728 RRARVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTITGLQPG 1786
                V     +  TISW    +T + + +   P    + P+Q  +     S T+TGL  G
Sbjct: 2051 YPPNVGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2109

Query: 1787 TDYKIYLYTLNDNAR 1801
              Y I +  L D  R
Sbjct: 2110 ATYNIIVEALKDQQR 2124



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2109 CTCFGGQRG 2117
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2147 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2206

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2207 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2262

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2263 CTCFGGQRG 2271



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2130 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2190 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2235

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2236 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2267



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2118 WRC 2120
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2159 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2214

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2271

Query: 597  WHC 599
            W C
Sbjct: 2272 WRC 2274



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2118 WRCD 2121
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2159 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2214

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2271

Query: 268  WKCE 271
            W+C+
Sbjct: 2272 WRCD 2275



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2197 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2253

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2254 KEY-LGAICSCTCFGGQRG-WRCD 2275



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2249

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2250 EQWQKEYLGAICSCTCFGGQRG 2271



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2134 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2190 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2234



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2145 QR 2146
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2239 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2298

Query: 106  YR 107
             R
Sbjct: 2299 QR 2300



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2191

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2192 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2226


>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
          Length = 2477

 Score = 2989 bits (7749), Expect = 0.0
 Identities = 1479/1992 (74%), Positives = 1612/1992 (80%), Gaps = 32/1992 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500

Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616

Query: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
            +    S+P+     T I  P+ ++ T V   S+S +W P +  +TGYRV  TPK   GP 
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676

Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
            K     PD + + + GL    +Y VSVYA   +  S+P   V T + N+  P+    TD 
Sbjct: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734

Query: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
               +I I+W +    ++ ++V  + P +G   +      +  +  + GL+PG++Y + + 
Sbjct: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794

Query: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851
             L+D+  S P++   STAI AP++L+F   TP SL   W PP  ++TGY ++    EK G
Sbjct: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854

Query: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG------------RK 1899
             P +E+     P  +   ++GL   T+Y + V ALK+   S P  G            R 
Sbjct: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911

Query: 1900 KTGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 1958
            +      +  TISW    +T + + +   P    + P+Q  +     S T+TGL  G  Y
Sbjct: 1912 RVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970

Query: 1959 NIIVEALKDQQR 1970
             I +  L D  R
Sbjct: 1971 KIYLYTLNDNAR 1982



 Score = 1038 bits (2685), Expect = 0.0
 Identities = 636/1617 (39%), Positives = 872/1617 (53%), Gaps = 132/1617 (8%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT-IKGLKPGVVYEGQLISIQQ 686
            I W  P+ S ++ Y +   P N  G   +  +P   N++  + GL PGV Y  ++ ++  
Sbjct: 925  IMWTPPE-SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAEVTGLSPGVTYYFKVFAVS- 981

Query: 687  YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT 746
            +G +            S P+T+   T    P      T+      T S+ +V W      
Sbjct: 982  HGRE------------SKPLTAQQTTKLDAP------TNLQFVNETDSTVLVRWTPPRAQ 1023

Query: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
            ++G+R+   L+  G   QY   PS +    + +L P  +Y V++  I  + E        
Sbjct: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLVAIKGNQESPKATGVF 1082

Query: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
             T  P +   P   +V +T+IV+ W+   AP  G+++   PS +G      +   + S+ 
Sbjct: 1083 TTLQPGSSIPPYNTEVTETTIVITWT--PAPRIGFKLGVRPS-QGGEAPREVTSDSGSIV 1139

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKV-TI 925
            +S L PGV+Y  TI  + + QE    ++ +  T       +  P +L      D  V T+
Sbjct: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT------PLSPPTNLHLEANPDTGVLTV 1193

Query: 926  MW---TPPESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTGLSPGVTYYFKVFA 979
             W   T P+  +TGYR+   P N  G+ G  L     +  +      LSPG+ Y   V+ 
Sbjct: 1194 SWERSTTPD--ITGYRITTTPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249

Query: 980  VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQ 1038
            V   +ES P++     ++   T+L FV+ TDS++ +RWTP  +  I GYR+TV     G 
Sbjct: 1250 VKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGI 1309

Query: 1039 PRQYN-VGPSVSKYPLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYN- 1095
            P   + V  SV  Y +  L+P  +Y +S++  I G + +P      TTL   +++PP   
Sbjct: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP------TTLTQQTAVPPPTD 1363

Query: 1096 ---TEVTETTIVITWTPAPRI---GFKLGVRPSQGGE--APREVTSDSGSIVVSGLTPGV 1147
               T +   T+ +TW P P I    F +   P +  E  A   ++    ++V++ L PG 
Sbjct: 1364 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1423

Query: 1148 EYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW--ERSTTPDITG 1205
            EYV ++  + + Q    P+  +  T L  PT +   ++      TV W   R+T   ITG
Sbjct: 1424 EYVVSVSSVYE-QHESTPLRGRQKTGLDSPTGIDF-SDITANSFTVHWIAPRAT---ITG 1478

Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP 1265
            YRI   P +   G   E+ V   ++S T  NL+PG EY VS+  +   +ES  +      
Sbjct: 1479 YRIRHHPEHFS-GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST 1537

Query: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
                P DL      P ++ ++W   P++ +  + + Y        V E ++  S +   +
Sbjct: 1538 VSDVPRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1596

Query: 1326 TNLLPGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP 1381
            + L PG +Y ++V +V  + +S     P+    +T +D P+ +  +D+  NS +V W+  
Sbjct: 1597 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1656

Query: 1382 RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLI 1441
             + +TGYR+   P++  G  +       +  +T+  L P  EYVVS+ A N   ES  L+
Sbjct: 1657 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716

Query: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE-FTVP-GS 1499
                T  D P+ L        S+ I+W++P   V  YR+TY        + E F  P G 
Sbjct: 1717 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP--EDGIHELFPAPDGE 1774

Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
            + TA + GL+PG +YT++V A+         S+P+     T I  P+ ++ T V   S+S
Sbjct: 1775 EDTAELQGLRPGSEYTVSVVAL----HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1830

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
             +W P +  +TGYRV  TPK   GP K     PD + + + GL    +Y VSVYA   + 
Sbjct: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1890

Query: 1620 ESQPL--VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1677
             S+P   V T +  +  P   + T  T T+++  W      +TG++V   P     P++ 
Sbjct: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1950

Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATE 1737
              + PD  S  ++GL   T Y++ +Y L D   S P   V+     +  P   R    T 
Sbjct: 1951 -TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNLRFLATTP 2007

Query: 1738 TTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
             ++ +SW+     ITG+ +    P +    +    +P V   TITGL+PGT+Y IY+  L
Sbjct: 2008 NSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 2067

Query: 1797 NDNARSSPVV------------------IDASTAIDAPSNLR---FLA----TTPNSLLV 1831
             +N +S P++                  +     +D PS ++   F+      T N + +
Sbjct: 2068 KNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL 2127

Query: 1832 SWQPPRARITGYIIKYEKPG----SPPREVVP---RPRP---GVTEATITGLEP--GTEY 1879
                 +    G  + +E+ G    +PP    P   RPRP    V E    G  P    +Y
Sbjct: 2128 PGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDY 2187

Query: 1880 TIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFR 1939
             +Y      N  +        TGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFR
Sbjct: 2188 HLYPHGPGLNPNAS-------TGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFR 2240

Query: 1940 VPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDP 1999
            VPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDP
Sbjct: 2241 VPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDP 2300

Query: 2000 YTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGE 2059
            YTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGE
Sbjct: 2301 YTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGE 2360

Query: 2060 NGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWR 2119
            NGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWR
Sbjct: 2361 NGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWR 2420

Query: 2120 CDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2176
            CDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2421 CDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2477



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2109 CTCFGGQRG 2117
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2410 CTCFGGQRG 2418



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2118 WRC 2120
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418

Query: 597  WHC 599
            W C
Sbjct: 2419 WRC 2421



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2118 WRCD 2121
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418

Query: 268  WKCE 271
            W+C+
Sbjct: 2419 WRCD 2422



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2397 EQWQKEYLGAICSCTCFGGQRG 2418



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2145 QR 2146
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445

Query: 106  YR 107
             R
Sbjct: 2446 QR 2447



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373


>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score = 2989 bits (7749), Expect = 0.0
 Identities = 1479/1992 (74%), Positives = 1612/1992 (80%), Gaps = 32/1992 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500

Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616

Query: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
            +    S+P+     T I  P+ ++ T V   S+S +W P +  +TGYRV  TPK   GP 
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676

Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
            K     PD + + + GL    +Y VSVYA   +  S+P   V T + N+  P+    TD 
Sbjct: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734

Query: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
               +I I+W +    ++ ++V  + P +G   +      +  +  + GL+PG++Y + + 
Sbjct: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794

Query: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851
             L+D+  S P++   STAI AP++L+F   TP SL   W PP  ++TGY ++    EK G
Sbjct: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854

Query: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG------------RK 1899
             P +E+     P  +   ++GL   T+Y + V ALK+   S P  G            R 
Sbjct: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911

Query: 1900 KTGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 1958
            +      +  TISW    +T + + +   P    + P+Q  +     S T+TGL  G  Y
Sbjct: 1912 RVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970

Query: 1959 NIIVEALKDQQR 1970
             I +  L D  R
Sbjct: 1971 KIYLYTLNDNAR 1982



 Score = 1130 bits (2922), Expect = 0.0
 Identities = 717/1657 (43%), Positives = 920/1657 (55%), Gaps = 172/1657 (10%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            ++W+ PQ + I+ Y + + P    G   E  +P   NS T+  L+PGV Y   + ++++ 
Sbjct: 829  VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
             +QE T       +T TP +    +     F           E+T     + W      V
Sbjct: 886  -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934

Query: 748  SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
            +G+RV+   ++  G+  Q L + S  T   +  L PG  Y   V+ +S  G +S  L+  
Sbjct: 935  TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992

Query: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
            QTT  DAP +       D++++VRW+ P+A ITGYR+    +  G   + N+  + +   
Sbjct: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L +LQP  +Y +++ A++ NQES P      TT  P S   P        EVT+  + I 
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985
            WTP      G+++ V P    G    R   S +    V+GL+PGV Y + +  +  G+E 
Sbjct: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162

Query: 986  SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039
              P+  +  T L  PTNL      D+ VL V W   T P   ITGYR+T   T  ++G  
Sbjct: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220

Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT 1099
             +  V    S     NL P  EY VS+  +K ++ES   +       P  +   +  ++T
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF-VDIT 1279

Query: 1100 ETTIVITWTP---APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
            +++I + WTP   +  IG+++ V  +  G    E  V S  G   V+GL PG++Y  ++ 
Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339

Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
             L +G E  AP      T + PPT+L      PDT  + V+W    + D+T + +  +P 
Sbjct: 1340 TLINGGE-SAPTTLTQQTAVPPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPV 1396

Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
              ++ +  E  +    ++    NL PG EY VSV +V +  ES P+       +  PT +
Sbjct: 1397 KNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1455

Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
             F++I  ++  V W  P +  +T + +R+ P        E  +  S N++ LTNL PGTE
Sbjct: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514

Query: 1334 YVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH 1393
            YVVS+ ++  + ES  L G+Q T  D P  ++    T  S  + W AP  T+  YRI + 
Sbjct: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574

Query: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSD 1449
                +   +E  VP S+++ T++ L PG +Y +++ A+ GR +SP      S    T  D
Sbjct: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634

Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
             P  ++V      S+ + W   +  V  YR+T     G  P +  T    ++  TI GL+
Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
            P V+Y ++VYA    G+S    +P+     T ID+P  +  TDV  +SI + W      V
Sbjct: 1695 PTVEYVVSVYAQNPSGES----QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750

Query: 1570 TGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
            + YRVT ++P++G         G + T   ++GL+P  EY VSV A +   ESQPL+ T 
Sbjct: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809

Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
             T IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV
Sbjct: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869

Query: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748
            VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT
Sbjct: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929

Query: 1749 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808
            ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID
Sbjct: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989

Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868
            ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA
Sbjct: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049

Query: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHP 1928
            TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT Q    +T     P  DT   I     
Sbjct: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ----KTPFVTHPGYDTGNGI----- 2100

Query: 1929 VGTDEEPLQFRVPGTSTSATLTG----LTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 1984
                      ++PGTS      G                      RH+ R     VG   
Sbjct: 2101 ----------QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG--- 2147

Query: 1985 NEGLNQ------PTDDSCFDPYTVSHYAVGDEWERMS-----------------ESGFKL 2021
             E L+Q      P  D+    Y +S + VG + E +                   + + +
Sbjct: 2148 QEALSQTTISWAPFQDT--SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNI 2205

Query: 2022 LCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQ------------GENGQMMS---- 2065
            + + L     H +         N VN  + +  D              G+  + MS    
Sbjct: 2206 IVEALKDQQRH-KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGF 2264

Query: 2066 ---CTCLGNGKGEFKC-------------------------------------------D 2079
               C CLG G G F+C                                           D
Sbjct: 2265 KLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCD 2324

Query: 2080 PHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQS 2139
            PHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQS
Sbjct: 2325 PHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQS 2384

Query: 2140 YNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2176
            YNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2385 YNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2421



 Score = 1077 bits (2785), Expect = 0.0
 Identities = 642/1352 (47%), Positives = 807/1352 (59%), Gaps = 87/1352 (6%)

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814

Query: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868

Query: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928

Query: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988

Query: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V      G   
Sbjct: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035

Query: 952  QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
            +  P   N    V+      L P   Y   + A+   +ES   T   TT     +   + 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
             E T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151

Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
            ++  ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
               P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEV 1267

Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
               T+L      D+ +  + W    +  I GYRIT     G+     E+ V +     T 
Sbjct: 1268 PQLTDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTV 1325

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1294
              L PG++Y++SV T+ +  ES P + T   AVPPPTDLRFTNIGPDTMRVTWAPPPSID
Sbjct: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385

Query: 1295 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1354
            LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ
Sbjct: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445

Query: 1355 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
            KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT
Sbjct: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505

Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1474
            LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565

Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
            VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI
Sbjct: 1566 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
            SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ
Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685

Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTP 1654
            TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT I  P  L FT V   S+   W  
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745

Query: 1655 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVSVYALKDTLTSR 1712
            P  Q++ YRV  +  E    + E+  APD    +  + GL   ++Y VSV AL D + S+
Sbjct: 1746 PQGQVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQ 1803

Query: 1713 PAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR-TI 1771
            P  G  +T   +  P   + T  T T+++  W      +TG++V   P     P++   +
Sbjct: 1804 PLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1861

Query: 1772 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNLRFLATTPNSL 1829
             PD  S  ++GL   T Y++ +Y L D   S P   V+     +  P   R    T  ++
Sbjct: 1862 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1921

Query: 1830 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 1889
             +SW+     ITG+ +    P +    +    +P V   TITGL+PGT+Y IY+  L +N
Sbjct: 1922 TISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980

Query: 1890 QKSEPLIGRKKTGQEALSQ-----TT-----ISWAPFQ-DTSEYIISCHPVGTDEEPLQF 1938
             +S P++    T  +A S      TT     +SW P +   + YII     G+    +  
Sbjct: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040

Query: 1939 RVPGTSTSATLTGLTRGATYNIIVEALKDQQR 1970
            R     T AT+TGL  G  Y I V ALK+ Q+
Sbjct: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072



 Score =  494 bits (1273), Expect = e-139
 Identities = 357/1295 (27%), Positives = 594/1295 (45%), Gaps = 88/1295 (6%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718

Query: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778

Query: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832

Query: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891

Query: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V       P +
Sbjct: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949

Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
            +     +S+     +  L P   Y   + A+   +ES   T   TT     +   +  E 
Sbjct: 950  HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008

Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
            T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  ++ 
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067

Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
             ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++   
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAVPPP 1270
            P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  + PP
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177

Query: 1271 TDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTN 1327
            T+L      PDT  + V+W    + D+T + +  +P   ++ +  E  +    ++    N
Sbjct: 1178 TNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236

Query: 1328 LLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRA-TIT 1386
            L PG EY VSV +V +  ES P+       +   T + F DIT +S  + W    + TI 
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTII 1296

Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQS 1445
            GYRI            ED V  S    T+T L PG +Y +S++ L NG E +P  + QQ+
Sbjct: 1297 GYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQT 1356

Query: 1446 TVSDVPRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
             V   P DL      P ++ ++W   P++ +  + + Y        V E ++  S +   
Sbjct: 1357 AVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1415

Query: 1505 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP 1564
            ++ L PG +Y ++V +V  + +S     P+    +T +D P+ +  +D+  NS +V W+ 
Sbjct: 1416 LTNLLPGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1471

Query: 1565 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1624
              + +TGYR+   P++  G  +       +  +T+  L P  EYVVS+ A N   ES  L
Sbjct: 1472 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1531

Query: 1625 VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1684
            +    T    P DL+    TPTSL   W  P V +  YR+         P++E  +    
Sbjct: 1532 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1591

Query: 1685 SSVVVSGLMVATKYEVSVYALK----DTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
            S+  +SGL     Y ++VYA+        +S+P    +     +  P + +VTD  + +I
Sbjct: 1592 STATISGLKPGVDYTITVYAVTGRGDSPASSKPIS--INYRTEIDKPSQMQVTDVQDNSI 1649

Query: 1741 TISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1799
            ++ W   +  +TG++V   P NG  P + +T  PD    TI GLQP  +Y + +Y  N +
Sbjct: 1650 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709

Query: 1800 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 1859
              S P+V  A T ID P  L F     +S+ ++W+ P+ +++ Y + Y  P     E+ P
Sbjct: 1710 GESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1769

Query: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA--------LSQTTI 1911
             P      A + GL PG+EYT+ V+AL ++ +S+PLIG + T   A        ++ T++
Sbjct: 1770 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSL 1829

Query: 1912 S--WAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 1968
            S  W P     + Y +   P        +  +   S+S  ++GL     Y + V ALKD 
Sbjct: 1830 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1889

Query: 1969 QRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003
               +  + VVT   +V+        D+     T+S
Sbjct: 1890 LTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1924



 Score =  417 bits (1073), Expect = e-116
 Identities = 354/1221 (28%), Positives = 545/1221 (44%), Gaps = 120/1221 (9%)

Query: 607  SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
            SS  P    +TET     +  I W    P+    + L  RP       +E T      S 
Sbjct: 1089 SSIPPYNTEVTET-----TIVITWT---PAPRIGFKLGVRPSQGGEAPREVTSDS--GSI 1138

Query: 667  TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
             + GL PGV Y    I + + G +              P+ +  VT  + P +  +  + 
Sbjct: 1139 VVSGLTPGVEYV-YTIQVLRDGQER-----------DAPIVNKVVTPLSPPTNLHLEANP 1186

Query: 727  SVTEITASSFVVSWV-SASDTVSGFRVEYELSEEGDEPQYLD--LPSTATSVNIPDLLPG 783
                +T     VSW  S +  ++G+R+       G +   L+  + +  +S    +L PG
Sbjct: 1187 DTGVLT-----VSWERSTTPDITGYRIT-TTPTNGQQGNSLEEVVHADQSSCTFDNLSPG 1240

Query: 784  RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSR-PQAPITG 840
             +Y V+VY + +D E   I   S T  P+ P    +  VD  D+SI +RW+    + I G
Sbjct: 1241 LEYNVSVYTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIG 1297

Query: 841  YRIVYSPSVEGSST-ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
            YRI    + EG    E  +  +    T++ L+PG+ Y+I++  +    ES P  + Q+T 
Sbjct: 1298 YRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357

Query: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISR 958
                   VP P DL+F  +    + + W PP S  +T + V   PV    E    L IS 
Sbjct: 1358 -------VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISP 1409

Query: 959  NTFAEV-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
            +  A V T L PG  Y   V +V    ES PL  +Q T LD+PT + F + T ++  V W
Sbjct: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1469

Query: 1018 TPPRAQITGYRLTVGLTR-RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
              PRA ITGYR+        G+PR+  V  S +   L NL P +EY VS+VA+ G +ESP
Sbjct: 1470 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1529

Query: 1077 KATGVFTTLQPGSSIPPYNTEV---TETTIVITW-TPAPRIGFKLGVRPSQGGEAPRE-- 1130
               G  +T+    S  P + EV   T T+++I+W  PA  + +        GG +P +  
Sbjct: 1530 LLIGQQSTV----SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1585

Query: 1131 -VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEANP 1186
             V     +  +SGL PGV+Y  T+  +    D      PI     T +  P+ + +    
Sbjct: 1586 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645

Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246
            D  + +V W  S++P +TGYR+TTTP NG  G +  +    DQ+  T + L P +EY VS
Sbjct: 1646 DNSI-SVKWLPSSSP-VTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702

Query: 1247 VYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1306
            VY      ES P+  T +  +  P  L FT++  D++++ W  P    ++ + V YS   
Sbjct: 1703 VYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG-QVSRYRVTYS--S 1759

Query: 1307 NEEDVAELSISPS--DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1364
             E+ + EL  +P   ++   L  L PG+EY VSV ++++  ES PL G Q T + +PT +
Sbjct: 1760 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDL 1819

Query: 1365 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
             F+ +T  S +  W  P   +TGYR+R  P+  +G  +E  +    +S+ ++ L   T+Y
Sbjct: 1820 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDV--PRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1482
             VS+ AL     S    G  +T+ +V  PR   V  AT T++ ISW     T+  +++  
Sbjct: 1880 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1939

Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
                G +P+Q    P  +S  TI+GL+PG DY I +Y +       A S P+ I+  T I
Sbjct: 1940 VPANGQTPIQRTIKPDVRSY-TITGLQPGTDYKIYLYTLNDN----ARSSPVVIDASTAI 1994

Query: 1543 DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
            D PS ++      NS+ V W P  + +TGY +       P         P  TE TI GL
Sbjct: 1995 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 2054

Query: 1603 QPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPN-VQLTG 1661
            +P  EY + V A   + +S+PL+             K  Q TP      +   N +QL G
Sbjct: 2055 EPGTEYTIYVIALKNNQKSEPLIGRK----------KTVQKTPFVTHPGYDTGNGIQLPG 2104

Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721
                                        SG   +   ++         T+ P     T +
Sbjct: 2105 ---------------------------TSGQQPSVGQQMIFEEHGFRRTTPPT--TATPI 2135

Query: 1722 ENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTI 1780
             +   P    V     +  TISW    +T + + +   P    + P+Q  +     S T+
Sbjct: 2136 RHRPRPYPPNVGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATL 2194

Query: 1781 TGLQPGTDYKIYLYTLNDNAR 1801
            TGL  G  Y I +  L D  R
Sbjct: 2195 TGLTRGATYNIIVEALKDQQR 2215



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2109 CTCFGGQRG 2117
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2354 CTCFGGQRG 2362



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2118 WRC 2120
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362

Query: 597  WHC 599
            W C
Sbjct: 2363 WRC 2365



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2118 WRCD 2121
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362

Query: 268  WKCE 271
            W+C+
Sbjct: 2363 WRCD 2366



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2341 EQWQKEYLGAICSCTCFGGQRG 2362



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2145 QR 2146
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389

Query: 106  YR 107
             R
Sbjct: 2390 QR 2391



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317


>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
          Length = 657

 Score = 1440 bits (3728), Expect = 0.0
 Identities = 647/647 (100%), Positives = 647/647 (100%)

Query: 1   MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
           MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1   MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61  INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
           INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61  INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
           WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
           PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
           RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
           QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
           VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
           HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
           GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
           LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
           PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647



 Score =  115 bits (287), Expect = 6e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2109 CTCFGGQRG 2117
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2118 WRC 2120
            W C
Sbjct: 597  WHC 599



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2118 WRCD 2121
            W+C+
Sbjct: 268  WKCE 271



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2145 QR 2146
             R
Sbjct: 106  YR 107



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339


>gi|153946395 tenascin C precursor [Homo sapiens]
          Length = 2201

 Score =  364 bits (935), Expect = e-100
 Identities = 341/1403 (24%), Positives = 585/1403 (41%), Gaps = 86/1403 (6%)

Query: 609  SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
            S P ++ +TE   +  +  + W+      +++Y++ + P +  G   +  +PG   S  I
Sbjct: 624  SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679

Query: 669  KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
            + L+PGV Y  ++ +I +                S PV++   T    P           
Sbjct: 680  QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720

Query: 729  TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
              I  +S  V W         + + +    + DE +    L    TS     L PG++Y 
Sbjct: 721  KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780

Query: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
            ++++ I ++  +   L    TT  DAP    V  V DT+ ++ W +P A I G  + Y  
Sbjct: 781  ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839

Query: 847  PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
              V G  T ++L E  N  ++ +L+P  +Y +++ +   +  S P   +  TTG      
Sbjct: 840  KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
            + +PR+L+ V  TD  +T+ W   ++A+  YR+   P++  G+H +  +P S+   T   
Sbjct: 893  LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
            +TGL PG  Y   V AV   +ES P T    T+LD P +LQ     ++++ + W  P A+
Sbjct: 952  LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011

Query: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
               YRL   L   GQ     +  + + Y LR L+P  EY V L A KG  +S  A    +
Sbjct: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070

Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
            T Q         TEV    + + WT A +    F + V+ +   EA R +T      ++ 
Sbjct: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130

Query: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
            + GL     Y  +I  +  G     P+++ +  T  +P     + A      L ++W   
Sbjct: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
            T P+   Y         Q+ +++E      V     S     L     Y +++  V  D 
Sbjct: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242

Query: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
             + P+S + +   VP   +L  T +  D +R+ W  P       F ++       E+   
Sbjct: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301

Query: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
            L++  S  ++ +  L  GT Y V++      H + PL     T  L     +  S++  +
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361

Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
               ++W A       + I+    +     +   +P S  ++ +  L   T Y VSI  + 
Sbjct: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421

Query: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
                +P+L  + ST  +    +L V   TP S  +SW A       + I   ++      
Sbjct: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
             E+ + G++ TA ISGL P  D+ + +      G +P+  +K IS    TE +     + 
Sbjct: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536

Query: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
            ++D+     +V W+ S +    + VT          +  T    Q ++ + GL   + Y 
Sbjct: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596

Query: 1610 VSVYAQNPSGESQPLVQTAVTTI-PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668
            V V       +++PL    VT   P   +L  +  TP      WT        + +++  
Sbjct: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656

Query: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR 1728
             +K     EI L     +  ++GL  AT+YE+ +Y +     S+    + TT   +  P+
Sbjct: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPK 1714

Query: 1729 RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
                +D TE + T+SWR  T  +  F++  VP  G TP   T+        +  L PG +
Sbjct: 1715 EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVE 1774

Query: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
            Y + +  +     S PV    +TA+D PS L     T +  L  WQP  A +  Y+I Y 
Sbjct: 1775 YLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY- 1833

Query: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG---------RK 1899
              G    E+         E  +T LEP TEYT+ + A K  QKS  +           R 
Sbjct: 1834 -TGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD 1892

Query: 1900 KTGQEALSQTT-ISWAPFQ-DTSEYIISCHPV-GTDEEPLQFRVPGTSTSATLTGLTRGA 1956
             T  E  S+T  ++W P +   + Y++    V GT +E +   V   +TS +L  L+   
Sbjct: 1893 LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVI---VGPDTTSYSLADLSPST 1949

Query: 1957 TYNIIVEALKDQQRHKVREEVVT 1979
             Y   ++AL    R  + + + T
Sbjct: 1950 HYTAKIQALNGPLRSNMIQTIFT 1972



 Score =  278 bits (710), Expect = 5e-74
 Identities = 271/1105 (24%), Positives = 440/1105 (39%), Gaps = 52/1105 (4%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P+DL   EVT+  V + W   E  VT Y V   P +  G   Q       T   +  
Sbjct: 623  VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
            L PGV Y+ +VFA+   ++S P++A+  T L AP  L+F +  +++V V W P       
Sbjct: 682  LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741

Query: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
            + +    +     G+  +    P  S Y    L P  EY +SL  +K N   P    V T
Sbjct: 742  WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800

Query: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
            T L   S I     +VT+TT +ITW  P   I G +L  G++   G     ++T D    
Sbjct: 801  TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858

Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
             +  L P  EY  ++ + R G     P      T L  P NL   +  D  + T+ W R+
Sbjct: 859  SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
                I  YRI   P +G  G+  E  V   Q   +  T   L PG EY + V  VK+DKE
Sbjct: 916  GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973

Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
            S P +      +  P DL+ +     ++ + W  P +     + + YS    +     + 
Sbjct: 974  SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030

Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
            +  +  + VL  L PG EY V +++   +H+S P R +  T        +  +++  +  
Sbjct: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090

Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
             ++W A       + I+    +     R   VP S  ++ +  L   T Y VSI  +   
Sbjct: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150

Query: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
              +P+L  + ST  + P   EVV A     +L ++W AP     Y+ I   E       Q
Sbjct: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209

Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
              TVPG   +  + GLK    YTIT+  VT       S+ P+S+   T E+     + VT
Sbjct: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265

Query: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
            +V  +++ + W         + +     +        T       M I GL+    Y V+
Sbjct: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325

Query: 1612 VYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1670
            ++ +     ++PL    VT  +P   DL  ++V    L   WT  +     + ++V    
Sbjct: 1326 LHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVN 1385

Query: 1671 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1730
            K    + + L     +V + GL  AT Y VS+Y +     + P      +          
Sbjct: 1386 KVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRT-PVLSAEASTAKEPEIGNL 1444

Query: 1731 RVTDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDY 1789
             V+D T  +  +SW         F ++ + +N     ++  I    R+  I+GL P TD+
Sbjct: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504

Query: 1790 KIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
             +YL  L  + R+  +   A+T A+    NL      P    VSW         +++   
Sbjct: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVV 1564

Query: 1849 KPGS--PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQE-- 1904
              G    P+E          E  + GL  G  Y + V       +++PL     T  E  
Sbjct: 1565 DSGKLLDPQEFTLSGTQRKLE--LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPE 1622

Query: 1905 ----ALSQTT-----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 1954
                 +S  T     +SW   +     +++         EPL+  +     +  +TGL  
Sbjct: 1623 VDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLRE 1682

Query: 1955 GATYNIIVEALKDQQRHKVREEVVT 1979
               Y I +  +   +R +    + T
Sbjct: 1683 ATEYEIELYGISKGRRSQTVSAIAT 1707



 Score =  229 bits (584), Expect = 2e-59
 Identities = 252/1125 (22%), Positives = 465/1125 (41%), Gaps = 74/1125 (6%)

Query: 624  NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT---IKGLKPGVVYEGQ 680
            NS  ++W   + + I  Y +++ P +  G   E  +P    + T   + GL+PG  Y   
Sbjct: 907  NSITLEWRNGKAA-IDSYRIKYAPISG-GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIG 964

Query: 681  LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
            + ++++                S P T N  T   TP          V+E   +S  + W
Sbjct: 965  VSAVKE-------------DKESNPATINAATELDTP------KDLQVSETAETSLTLLW 1005

Query: 741  VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
             +       +R+ Y L     +   + LP   TS  +  L PG++Y  NV   +E G   
Sbjct: 1006 KTPLAKFDRYRLNYSLPT--GQWVGVQLPRNTTSYVLRGLEPGQEY--NVLLTAEKGRHK 1061

Query: 801  LILSTSQTTAPDAPP--DPTVDQVDDTSIVVRWSRPQAPITGYRI-VYSPSVEGSSTELN 857
               +  + +   AP   + TV +V    + + W+        + I V   +   ++  L 
Sbjct: 1062 SKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLT 1121

Query: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
            +P +  +V +  L+    Y ++IY V +    TPV+  + +TG       P+  ++   E
Sbjct: 1122 VPGSLRAVDIPGLKAATPYTVSIYGVIQGYR-TPVLSAEASTGE-----TPNLGEVVVAE 1175

Query: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYY 974
            V    + + WT PE A   + + V   +   E  Q L +    R+T  ++ GL     Y 
Sbjct: 1176 VGWDALKLNWTAPEGAYEYFFIQVQEADTV-EAAQNLTVPGGLRST--DLPGLKAATHYT 1232

Query: 975  FKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRWTPPRAQITGYRLTVG 1032
              +  V+    + PL+ +  T+ + P   NL     +   + + WT P      + + V 
Sbjct: 1233 ITIRGVTQDFSTTPLSVEVLTE-EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQ 1291

Query: 1033 LTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSS 1090
               +  +     V  S+    +  L+  + YTV+L   ++G+   P A  V T   P   
Sbjct: 1292 EADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLG 1351

Query: 1091 IPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIVVSGLTPG 1146
                + EV    + + WT A      F + V+     EA + +T      ++ + GL   
Sbjct: 1352 DLAVS-EVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAA 1410

Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT--NLHL-EANPDTGVLTVSWERSTTPDI 1203
              Y  +I  +  G     P+++   +    P   NL++ +  P++    +SW  +T    
Sbjct: 1411 TPYRVSIYGVIRGYR--TPVLSAEASTAKEPEIGNLNVSDITPES--FNLSW-MATDGIF 1465

Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI 1263
              + I    +N +   ++E  +   + +     L P  ++ V +  +     +  IS T 
Sbjct: 1466 ETFTIEIIDSN-RLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATA 1524

Query: 1264 IP-AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
               A+P   +L  ++I P    V+W    +    +FLV         D  E ++S +   
Sbjct: 1525 TTEALPLLENLTISDINPYGFTVSWMASENA-FDSFLVTVVDSGKLLDPQEFTLSGTQRK 1583

Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT-GIDFSDITANSFTVHWIAP 1381
            + L  L+ G  Y V VS   + H++ PLR    T  +     +  SD T + F + W A 
Sbjct: 1584 LELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTAD 1643

Query: 1382 RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLI 1441
                  + ++         P E  +     +  +T L   TEY + +  ++    S  + 
Sbjct: 1644 EGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVS 1703

Query: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
               +T    P+++     T  S  +SW AP   V  +RITY    G +P    TV G+K+
Sbjct: 1704 AIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKT 1762

Query: 1502 TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
               +  L PGV+Y +++ A+ G  +S    +P+S ++ T +D PS +   ++ D+    +
Sbjct: 1763 QTRLVKLIPGVEYLVSIIAMKGFEES----EPVSGSFTTALDGPSGLVTANITDSEALAR 1818

Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
            W P+ + V  Y ++ T +  P  T+T +   +  E  +  L+P  EY + ++A+    +S
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSG--NTVEYALTDLEPATEYTLRIFAEKGPQKS 1876

Query: 1622 QPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681
              +     T + +P DL  T+V   +    W PP   +TGY +    +   G +KE+ + 
Sbjct: 1877 STITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVG 1934

Query: 1682 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
            PD++S  ++ L  +T Y   + AL   L S   Q + TT+  + P
Sbjct: 1935 PDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979



 Score =  207 bits (526), Expect = 1e-52
 Identities = 145/564 (25%), Positives = 249/564 (44%), Gaps = 29/564 (5%)

Query: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
            G+  +    P+DL V   T  ++ ++WD   + V  Y + Y  T       +F VPG ++
Sbjct: 617  GEDCSEVSPPKDLVVTEVTEETVNLAWDNE-MRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675

Query: 1502 TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
            +  I  L+PGV+Y I V+A+         S P+S    T +  P  ++   +++ S+ V+
Sbjct: 676  STIIQELEPGVEYFIRVFAILEN----KKSIPVSARVATYLPAPEGLKFKSIKETSVEVE 731

Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            W P       + +     N     + TK+    +T     GL P  EY +S++    +  
Sbjct: 732  WDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTR 791

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
               L +   T + AP+ ++   VT T+    W  P  ++ G  +    K+  G    I+L
Sbjct: 792  GPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851

Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
              D +   +  L   T+YEVS+ + +  ++S PA+   TT   +  PR  R    T+ +I
Sbjct: 852  TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTT--GLDAPRNLRRVSQTDNSI 909

Query: 1741 TISWRTKTETITGFQVDAVPANG----QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
            T+ WR     I  +++   P +G    +  + ++ +   ++ T+TGL+PGT+Y I +  +
Sbjct: 910  TLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAV 968

Query: 1797 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKP-GSPPR 1855
             ++  S+P  I+A+T +D P +L+   T   SL + W+ P A+   Y + Y  P G    
Sbjct: 969  KEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVG 1028

Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQ----EALSQTTI 1911
              +PR     T   + GLEPG EY + + A K   KS+P   +  T Q    E L+ T +
Sbjct: 1029 VQLPR---NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEV 1085

Query: 1912 SW--------APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE 1963
             W        A  Q    +II        E      VPG+  +  + GL     Y + + 
Sbjct: 1086 GWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIY 1145

Query: 1964 ALKDQQRHKVREEVVTVGNSVNEG 1987
             +    R  V     + G + N G
Sbjct: 1146 GVIQGYRTPVLSAEASTGETPNLG 1169



 Score =  153 bits (386), Expect = 2e-36
 Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W A   ++   ++++ +  N V   +  T+PG L +  I GL+    Y   +  + + 
Sbjct: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
            G++             TPV S   +    P       + +V++IT  SF +SW++     
Sbjct: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
              F +E   S    E    ++     + +I  L P   +IV +  ++       I +T+ 
Sbjct: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525

Query: 808  TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
            T A     + T+  ++     V W   +     + +    S +     E  L  T   + 
Sbjct: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L  L  G+ Y + +    +  ++ P+  +  T   P  D      +L   + T     + 
Sbjct: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            WT  E     + + +       E  +   ++     ++TGL     Y  +++ +S GR S
Sbjct: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699

Query: 987  KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
            + ++A  TT + +P  + F + T+++  V W  P AQ+  +R+T      G P    V  
Sbjct: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759

Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
            + ++  L  L P  EY VS++A+KG +ES   +G FTT   G S       +T++  +  
Sbjct: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818

Query: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
            W PA      + +     +  E  R V+ ++    ++ L P  EY   I     G ++ +
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877

Query: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
             I  K  T L  P +L   E   +T +LT  W R     +TGY +     +   G   E 
Sbjct: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
            +V  D +S +  +LSP   Y   +  +     S     I  TI    P P D     +  
Sbjct: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991

Query: 1281 DT 1282
            DT
Sbjct: 1992 DT 1993


>gi|157384973 tenascin R [Homo sapiens]
          Length = 1358

 Score =  356 bits (913), Expect = 2e-97
 Identities = 266/878 (30%), Positives = 413/878 (47%), Gaps = 56/878 (6%)

Query: 783  GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
            G++  +N        E+ L +       PD    APP D  V  + D SI + W  P A 
Sbjct: 293  GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351

Query: 838  ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
            +T Y I Y P+  G    +  +P   + VT+++L+PG+ YNI++YAV  N  S P+  + 
Sbjct: 352  VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411

Query: 897  ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
             T        + +P+ LQF  +T+  V + W P   +  G+ +  IP N  G    ++P 
Sbjct: 412  AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
               +F + TGL PG  Y   V A+     S P +A  +T +D PT +   + +D+   V 
Sbjct: 465  DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523

Query: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
            W PPRA++    L  GL    G    + + P +S+Y ++ L+P S Y VS+ A++G  ES
Sbjct: 524  WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
              AT  FTT        P N  V   T T++ + W  + A    +K+ V  +  GE   E
Sbjct: 584  DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638

Query: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
            V    G        ++ L PG EY   I  + + Q+   P      T L  P +L + A+
Sbjct: 639  VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
             +T + ++ W +++ P I  YRIT TP++   G + E  V  D++S T  +L PG EY +
Sbjct: 698  SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752

Query: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
            SV   +  ++S+  +        P + L F+++   ++ +TW+  PS      ++ YSP 
Sbjct: 753  SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
              EE++ E+S+  +    VL  L P TEY+V++ +V+    S P+ G   TG+D P  I 
Sbjct: 812  DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871

Query: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
             S++T +S  V W  P A+   YR+ + P    GR     VP++    T+T L P TEY 
Sbjct: 872  ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930

Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
            +S+ ++ GREES  +     T  D P DL     TPT  L+ W AP   V  Y I  T+ 
Sbjct: 931  ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
               G    +   V G      +  L P   YT T+YA  G    P +S  IS N+ T +D
Sbjct: 991  AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
             P+ +  ++V   S  + W P  + +  Y    T K+  G  K      + T + +EGL 
Sbjct: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100

Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTT----IPAPTD 1637
               +Y V + A   +  S  +  TA TT     P P D
Sbjct: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFTTGGRVFPHPQD 1137



 Score =  310 bits (794), Expect = 1e-83
 Identities = 235/831 (28%), Positives = 375/831 (45%), Gaps = 45/831 (5%)

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            ++PP +L +    D  +  + W+      +T Y I+  PT    G  L++ V  D S  T
Sbjct: 326  VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
               L PGL YN+SVY V  +  S+PI+  +   +  P  L+F  I   T+ V W P  S 
Sbjct: 382  ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440

Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
                + + + P  NE  V  ++  PSD  +   T L PG EY+V+V ++ EQ  S P   
Sbjct: 441  SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498

Query: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
               T +D PT I   D++     V WI PRA +    +++      G     R+    + 
Sbjct: 499  SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558

Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             ++  L PG+ Y VS+ A+ G  ES     Q +T  D P++L V + T TSL + WD   
Sbjct: 559  YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618

Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
              V+ Y++ Y    G     E  VP   G  + AT++ L PG +Y + + AV     +  
Sbjct: 619  AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673

Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
             S P ++N RTE+D P  + VT   + SIS+ W  +S P+  YR+T TP +G       T
Sbjct: 674  QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731

Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS 1649
               D+T  T+  L+P  EY++SV A+    +S      A T     + L F+ VT +S++
Sbjct: 732  VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791

Query: 1650 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1709
              W+ P+       +  +P+++   M E++L       V+ GL  AT+Y V++ A+  T+
Sbjct: 792  ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851

Query: 1710 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1769
            TS P  G +TT   + PP+   +++ T+ ++ +SW     +   ++V   P         
Sbjct: 852  TSEPIVGSITT--GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSS 909

Query: 1770 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL 1829
             +   V  +TIT L P T+Y+I L ++     S  +     TA+D P +L     TP   
Sbjct: 910  VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969

Query: 1830 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA-TITGLEPGTEYTIYVIALKN 1888
            L+ W+ P   +  Y+I           ++     GV+E   +  L P T YT  + A   
Sbjct: 970  LLQWKAPVGEVENYVIVLTHFAVAGETILV---DGVSEEFRLVDLLPSTHYTATMYATNG 1026

Query: 1889 NQKS-----------EP---LIGRKKTGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDE 1933
               S           +P   L   + T Q AL    ISW P + +   Y+++     TD 
Sbjct: 1027 PLTSGTISTNFSTLLDPPANLTASEVTRQSAL----ISWQPPRAEIENYVLTYK--STDG 1080

Query: 1934 EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 1984
               +  V    T   L GL     Y ++++A +D     +     T G  V
Sbjct: 1081 SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRV 1131



 Score =  271 bits (692), Expect = 7e-72
 Identities = 211/831 (25%), Positives = 361/831 (43%), Gaps = 24/831 (2%)

Query: 902  PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
            P    V  P DL+   ++D  + + W  P  AVT Y +   P  L G   Q+      + 
Sbjct: 321  PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379

Query: 962  AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
              +T L PG+TY   V+AV     S P+TA+  T L  P  LQF   T++TV V+W P  
Sbjct: 380  VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439

Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
                G+ ++             V   V+ +    L+P  EY V++VA+K    SP  +  
Sbjct: 440  FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499

Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
             +T+  G +      +V++T   + W P PR     I  K G+   +GG     +     
Sbjct: 500  VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
               V  L PG  Y  ++  +R   E D+    +  T +  P NL + +   T  L + W+
Sbjct: 558  QYSVQALRPGSRYEVSVSAVRGTNESDSA-TTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615

Query: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
             S   ++  Y++  +   G+Q +  L        +  T  +L PG EY V +  V + ++
Sbjct: 616  NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674

Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
            SVP +      +  P DL  T     ++ + W    S  + ++ + ++P  +    +E++
Sbjct: 675  SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTP--SSGIASEVT 731

Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
            +     +  LT+L PG EY++SV++   + +S        TG    + + FS +T++S  
Sbjct: 732  VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791

Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
            + W  P        + + P        E  +  ++    L  L P TEY+V++VA++G  
Sbjct: 792  ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851

Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
             S  ++G  +T  D P+D+ +   T  S+++SW  P  +  YYR++Y  T     +    
Sbjct: 852  TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910

Query: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
            VP + +  TI+ L P  +Y I++ +V GR +    S+ I     T +D P  +  T++  
Sbjct: 911  VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966

Query: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
                ++W      V  Y +  T     G  +T        E  +  L P+  Y  ++YA 
Sbjct: 967  TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024

Query: 1616 NPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
            N    S  +     T +  P +L  ++VT  S    W PP  ++  Y   +T K   G  
Sbjct: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSR 1082

Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
            KE+ +  + + + + GL+  T Y V + A +DT  S       TT   V P
Sbjct: 1083 KELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133



 Score =  245 bits (626), Expect = 3e-64
 Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            ++W+ P    +++Y++ ++P    G   +  +PG  +  TI  L+PG+ Y          
Sbjct: 344  LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
                ++ +   +   S P+T+   T  +TP      T      IT ++  V W   S + 
Sbjct: 392  ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
             G+ + + + +  +      +PS  TS N   L PG +YIVNV  + E   +S   S S 
Sbjct: 443  DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500

Query: 808  TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
            +T  D P    V  V DT   V W  P+A +    + Y     EG  T   L    +  +
Sbjct: 501  STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            +  L+PG +Y +++ AV    ES     Q  T        + +P++L+    T   + + 
Sbjct: 561  VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
            W   E+ V  Y+  V+   L GE    + + R     T A +T L PG  Y   + AV +
Sbjct: 614  WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671

Query: 983  GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
             ++S P T    T+LD+P +L     +++++ + WT     I  YR+T      G   + 
Sbjct: 672  SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730

Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
             V    + Y L +L+P +EY +S+ A +G Q+S ++T   FT  +P S +  + + VT +
Sbjct: 731  TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788

Query: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
            ++ ITW+    PA R+   L   P    E   EV+ D+     V+ GL P  EY+  + V
Sbjct: 789  SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845

Query: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
               G     PIV  + T + PP ++ + +N     + VSW          YR++  PT  
Sbjct: 846  AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901

Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
            Q G     VV    +  T   L+P  EY +S+ +V+  +ES  I   +  A+  P DL  
Sbjct: 902  QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961

Query: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
            TNI P    + W AP   ++    ++ +  V  E     + +        L +LLP T Y
Sbjct: 962  TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017

Query: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
              ++ +      S  +     T LD P  +  S++T  S  + W  PRA I  Y + +  
Sbjct: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075

Query: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            +   G  +E  V      I L  L   T+Y V + A
Sbjct: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111



 Score =  139 bits (349), Expect = 4e-32
 Identities = 89/354 (25%), Positives = 161/354 (45%), Gaps = 16/354 (4%)

Query: 1630 TTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1689
            + +  P DL+   ++  S+  +W  P + +T Y +   P    G   +  +  D S V +
Sbjct: 324  SAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSGVTI 382

Query: 1690 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1749
            + L     Y +SVYA+   + S P    V T  ++S P+  +    TETT+ + W   + 
Sbjct: 383  TELEPGLTYNISVYAVISNILSLPITAKVAT--HLSTPQGLQFKTITETTVEVQWEPFSF 440

Query: 1750 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1809
            +  G+++  +P N +  +   +  DV S+  TGL+PG +Y + +  L + ARS P     
Sbjct: 441  SFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASV 500

Query: 1810 STAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
            ST ID P+ +     +     V W PPRA++   ++KY   G        R +P +++ +
Sbjct: 501  STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560

Query: 1870 ITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT----------GQEALSQTTISWAPFQ-D 1918
            +  L PG+ Y + V A++   +S+    +  T          G    +   + W   + +
Sbjct: 561  VQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAE 620

Query: 1919 TSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 1970
              EY +    +  ++  E L  R  G +T ATLT L  G  Y + + A+ + Q+
Sbjct: 621  VQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674



 Score =  134 bits (338), Expect = 7e-31
 Identities = 121/467 (25%), Positives = 191/467 (40%), Gaps = 35/467 (7%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
            T S   S  + W       I  Y + + P + +    E T+P    SYT+  L+PG  Y 
Sbjct: 695  TASSETSISLIWTKAS-GPIDHYRITFTPSSGIA--SEVTVPKDRTSYTLTDLEPGAEY- 750

Query: 679  GQLISIQ-QYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
              +IS+  + G Q+           S   T +  TG    F P+  +    + +T+SS  
Sbjct: 751  --IISVTAERGRQQ-----------SLESTVDAFTG----FRPI--SHLHFSHVTSSSVN 791

Query: 738  VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
            ++W   S       + Y   +E +E   + L +T     +  L P  +YIVN+  +    
Sbjct: 792  ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851

Query: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
                I+  S TT  D P D T+  V   S++V WS P A    YR+ Y P+  G      
Sbjct: 852  TSEPIVG-SITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSV 910

Query: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
            +P T    T++ L P  +Y I++ +V   +ES  +     T        + +P DL    
Sbjct: 911  VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-------AMDNPVDLIATN 963

Query: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
            +T  +  + W  P   V  Y + +    + GE      +S      +  L P   Y   +
Sbjct: 964  ITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEE--FRLVDLLPSTHYTATM 1021

Query: 978  FAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRG 1037
            +A +    S  ++   +T LD P NL     T  + L+ W PPRA+I  Y LT   T  G
Sbjct: 1022 YATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKST-DG 1080

Query: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
              ++  V    +   L  L   ++YTV L A +    S   +  FTT
Sbjct: 1081 SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTT 1127


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score =  342 bits (876), Expect = 3e-93
 Identities = 349/1417 (24%), Positives = 571/1417 (40%), Gaps = 136/1417 (9%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931

Query: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991

Query: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166

Query: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225

Query: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270

Query: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330

Query: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390

Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446

Query: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
              EY V+VY+V +D+ S P+  T      P   L   ++GP TM V W P      T ++
Sbjct: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504

Query: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
            + Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V     S P+  R+ T 
Sbjct: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564

Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415
             L  P  +   D+T ++  V W      +  Y +R+  PE      +E  V  S  S +L
Sbjct: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621

Query: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474
             +L   T Y VS+ A++   ESP +  Q++T     P +L++   T      +WD  A  
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681

Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530
            V  YRIT+   G +S   E  + G ++T     L P   Y +++ A+    +   D   S
Sbjct: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740

Query: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
             + + I   T+  K  P  +QV +   NS++VKW P+S  V  YR+T  P  G G  +T 
Sbjct: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799

Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTS 1647
            T G  Q  + ++ L+P   Y ++V +  P GE   +     T  +    +L+    + ++
Sbjct: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859

Query: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
            L+ +W         Y++   P    GP + + +  +++  ++  L   T Y V+V  +  
Sbjct: 1860 LNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 1918

Query: 1708 TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI 1767
                        TL      R  +V + T  ++ + W      +  ++V   P +G  P 
Sbjct: 1919 EGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 1977

Query: 1768 QRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATT 1825
            +  + P + R   +  L P T Y + L  L  +   +P      T     P NLR    T
Sbjct: 1978 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 2037

Query: 1826 PNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVTEATITGLEPGTEYTIY 1882
             NSL V+W      +  Y I Y      P +    VP  R  V    +  L+P T Y I 
Sbjct: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV---ILQPLQPDTPYKIT 2094

Query: 1883 VIALKNNQKSEPLIGRKKT-----------GQEALSQTTISWAPF-QDTSEYIISCHPVG 1930
            VIA+  +     L G  +T             E  ++  +SW P       Y I   PVG
Sbjct: 2095 VIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG 2154

Query: 1931 TDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 1967
            ++ EP++  V G  TS TL  L    TY++ V A  D
Sbjct: 2155 SN-EPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYD 2189



 Score =  290 bits (741), Expect = 1e-77
 Identities = 307/1304 (23%), Positives = 523/1304 (40%), Gaps = 97/1304 (7%)

Query: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697

Query: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756

Query: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810

Query: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868

Query: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928

Query: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048

Query: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107

Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165

Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308
            S P+    +  +   T +   + G + +    A          SI   NF    S +   
Sbjct: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225

Query: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364
             +V ++       A+   +  P TE+ ++      S+ +   + P +G      ++ TG+
Sbjct: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280

Query: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
              + I   +F T   + PRA   G  I              ++      +    +    E
Sbjct: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340

Query: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463
              + ++A +  +     +    ++S                    + P +L +   T  S
Sbjct: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400

Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523
              +SW  P+ +V  Y++ Y    G    QEF V   +++  +  LKP  +Y + VY+V  
Sbjct: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458

Query: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583
                   S+P+    +T       + + DV   ++ V+W P     TGY ++  P     
Sbjct: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514

Query: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKF 1640
            PT+ K    GP   +M +  L P  EY V+V A      S+P+    VT  +P P DLK 
Sbjct: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574

Query: 1641 TQVTPTSLSAQWTPPNVQLTGYRVRV-TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699
              VT ++++  W P   ++  Y VR  TP+E    +KE+ +    +S  +  L   T Y 
Sbjct: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSLKDLFSQTLYT 1631

Query: 1700 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1759
            VSV A+ D   S P     TT   V  P   ++T+ T      +W      ++ +++   
Sbjct: 1632 VSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWA 1690

Query: 1760 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI------ 1813
            P      ++  +  D  +     L P T Y++ +  +  +   S  +I +   +      
Sbjct: 1691 PFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQ 1750

Query: 1814 ---DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870
                 P NL+    T NSL V W P   R+  Y I Y+       E             +
Sbjct: 1751 APKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVL 1810

Query: 1871 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTG-----------QEALSQTTISWAPFQ-D 1918
              L+P T YTI V +L  + +   + GR KT              + S   + W   + +
Sbjct: 1811 QKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGN 1870

Query: 1919 TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 1962
              +Y +   P     E L   +PG +  A L  L    +Y + V
Sbjct: 1871 PRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDTSYTVTV 1913



 Score =  281 bits (718), Expect = 6e-75
 Identities = 238/913 (26%), Positives = 398/913 (43%), Gaps = 39/913 (4%)

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444

Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502

Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562

Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617

Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676

Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734

Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913

Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970

Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P +
Sbjct: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030

Query: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696
            L+    T  SLS  W   +  +  YR+  +P     P+ E    P   ++V++  L   T
Sbjct: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 2089

Query: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
             Y+++V A+ +        G   T+  + PP+   ++D   T   +SW      + G+++
Sbjct: 2090 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 2148

Query: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816
               P     P++  +  ++ SYT+  L P T Y + +Y   D+  S P+    +T     
Sbjct: 2149 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207

Query: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876
            ++L+      ++  V W P RA  T Y +K   P    R      R   T    TGL P 
Sbjct: 2208 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 2265

Query: 1877 TEYTIYVIALKNN 1889
            T+Y + V     N
Sbjct: 2266 TDYGVTVFVQTPN 2278



 Score =  273 bits (698), Expect = 1e-72
 Identities = 243/934 (26%), Positives = 397/934 (42%), Gaps = 57/934 (6%)

Query: 909  SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGL 967
            +P +L   E T     + WTPP  +V  Y+V+  PV+  G   Q   +SR  T   +  L
Sbjct: 1387 APSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS--GGKRQEFYVSRMETSTVLKDL 1444

Query: 968  SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGY 1027
             P   Y   V++V     S+PL   + T      +L   +   +T+ V+W P     TGY
Sbjct: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TGY 1503

Query: 1028 RLT---VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
             L+   V  T   +P++  +GP+V+   L +L P +EY V++ A+  +  S   T    T
Sbjct: 1504 ILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVT 1563

Query: 1085 LQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLT 1144
            L           +VT +T+ + W P P    K  VR     E  +EV  D      S   
Sbjct: 1564 LPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKD 1623

Query: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPD 1202
               + +YT+ V     E ++P V    T  P+  PTNL +      G    +W+   + D
Sbjct: 1624 LFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEG-FRGTWDHGAS-D 1681

Query: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE------- 1255
            ++ YRIT  P      + +E +++ D+++  F+NL+P   Y VS+  +  D+        
Sbjct: 1682 VSLYRITWAPFGSS--DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 1739

Query: 1256 ---SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
               ++PI  T  P    P +L+  N   +++ V W  P S  +  + + Y P   E +  
Sbjct: 1740 SERTLPILTTQAPK-SGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGEGNEQ 1797

Query: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITA 1371
              +I    N+VVL  L P T Y ++VSS+Y   E   + GR KT  L++   +   D + 
Sbjct: 1798 TTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPST 1857

Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            ++  V W         Y++ + P   +G P E   +P + N   L NL P T Y V++V 
Sbjct: 1858 STLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVP 1915

Query: 1431 LNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNS 1489
            +    +         T+   + R+++V   TP SL + WD     V  YR+ Y    G  
Sbjct: 1916 VYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTR 1975

Query: 1490 PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINYRTEIDKPS 1546
            P +   VPG+     +  L P   Y++ + A+   G+   SPA  + +  +       P 
Sbjct: 1976 PSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS------GPR 2029

Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1606
             ++V     NS+SV W  +  PV  YR+  +P  G    +  T    +  + ++ LQP  
Sbjct: 2030 NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 2089

Query: 1607 EYVVSVYAQNPSGESQPLVQTAVTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1665
             Y ++V A    G+   L     T  +  P ++  +    T     W P    + GY++ 
Sbjct: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149

Query: 1666 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1725
              P     PM+      + +S  +  L  +T Y+V+VYA  D+  S P     TTL    
Sbjct: 2150 YKPVGSNEPMEAF--VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY--- 2204

Query: 1726 PPRRARVTDATETTITISWRT------KTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
                  VTD    T  I W T           T +++   PA+G    + T++    S+ 
Sbjct: 2205 ----LNVTDLK--TYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHC 2258

Query: 1780 ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
             TGL P TDY + ++    N     V +   T +
Sbjct: 2259 FTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292



 Score =  262 bits (670), Expect = 2e-69
 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%)

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498

Query: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554

Query: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613

Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673

Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733

Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790

Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849

Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907

Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967

Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027

Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142

Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200

Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
             T     TDLK  Q+   +   +W+P     T YR++++P + T   +EI +    +S  
Sbjct: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 2258

Query: 1689 VSGLMVATKYEVSVY 1703
             +GL   T Y V+V+
Sbjct: 2259 FTGLSPDTDYGVTVF 2273



 Score =  260 bits (665), Expect = 9e-69
 Identities = 245/917 (26%), Positives = 400/917 (43%), Gaps = 67/917 (7%)

Query: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140
            PG    P N  ++E T     ++WTP       +K+   P  GG+     V+    S V+
Sbjct: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441

Query: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P  EYV  +  V+ D  E   P+     T   P  +L++    D G  T+  +   
Sbjct: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496

Query: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                TGY ++  P    +    +EV +    +     +L P  EY V+V  V  D  S P
Sbjct: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556

Query: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
            ++  +  +P +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +
Sbjct: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375
              S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F 
Sbjct: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672

Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
              W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E
Sbjct: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731

Query: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486
             ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + 
Sbjct: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541
            G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP++      
Sbjct: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846

Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
                  ++V D   ++++V+W  +      Y++   P  G GP +      +     +  
Sbjct: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902

Query: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1658
            LQP   Y   VV VY +   G +    +T +  +    +++    TP SL  +W P    
Sbjct: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960

Query: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1718
            +  YRV  +P + T P + I +  ++  V +  L+  T Y V++ AL       P+    
Sbjct: 1961 VLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQG 2020

Query: 1719 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
             TL   S PR  RV   T  +++++W      +  +++   P  G    + T  P  R+ 
Sbjct: 2021 RTLPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNN 2079

Query: 1779 TITG-LQPGTDYKIYLYTLNDNARSSPVVIDASTA-IDAPSNLRFLATTPNSLLVSWQPP 1836
             I   LQP T YKI +  + ++     +  +  T  +  P N+           VSW P 
Sbjct: 2080 VILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPS 2139

Query: 1837 RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL- 1895
             + + GY I Y+  GS   E +      +T  T+  L P T Y + V A  ++  S PL 
Sbjct: 2140 PSPVLGYKIVYKPVGS--NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLT 2197

Query: 1896 ---------IGRKKTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRVPGTST 1945
                     +   KT Q       + W+P +  + Y +   P  GT  + +  R  G+ T
Sbjct: 2198 DQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVR--GSET 2255

Query: 1946 SATLTGLTRGATYNIIV 1962
            S   TGL+    Y + V
Sbjct: 2256 SHCFTGLSPDTDYGVTV 2272



 Score =  213 bits (543), Expect = 1e-54
 Identities = 155/567 (27%), Positives = 252/567 (44%), Gaps = 17/567 (2%)

Query: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
            A  PP DL F+ +     +  W+P    ++ ++ + Y     +++V  +  + S  +VVL
Sbjct: 631  AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688

Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383
            ++L P T Y+V+V++ YE   S PL G + T     +P  +  +D T +SF + W     
Sbjct: 689  SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748

Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
             +  YRI + P    G  RE   P ++   TL NL P T+Y VS++          L G 
Sbjct: 749  RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807

Query: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
             +T  V   PRDL V   T +++ +SW      V+ Y +TY    G    QE TV G  +
Sbjct: 808  AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866

Query: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
               + GLK G  Y ++V A+  +G GD+             E   P  +   D+ D SI 
Sbjct: 867  NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
              W  +   V GYRV+         T  K    D     IE LQP  +Y +SV+A   SG
Sbjct: 923  AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982

Query: 1620 ESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678
            E +PL   A T +   +  LK  + T  ++   W P   ++  YRV   P  + G     
Sbjct: 983  EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGR-GKQMVA 1041

Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
             + P  +S V+  L   T Y+++V  +      +  QG  TT      PR  + +D T +
Sbjct: 1042 KVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101

Query: 1739 TITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
            +  ++W      + G++V   P      + +  + P   +  +  L+ GT YK+ ++ + 
Sbjct: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161

Query: 1798 DNARSSPVVIDASTAIDAPSNLRFLAT 1824
            D   SSP+V    T +   + +  L++
Sbjct: 1162 DGGESSPLVGQEMTTLSDTTVMPILSS 1188



 Score =  202 bits (515), Expect = 2e-51
 Identities = 238/984 (24%), Positives = 396/984 (40%), Gaps = 98/984 (9%)

Query: 599  CQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEAT 658
            C  ++       P  + I+E   +  S  + W  P  S + +Y + + P +  G+ +E  
Sbjct: 1376 CNSVKGPGDLEAPSNLVISERTHR--SFRVSWTPPSDS-VDRYKVEYYPVSG-GKRQEFY 1431

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTV--TGETT 716
            +     S  +K LKP   Y   + S+ +  + E  +   T  +   PV S  +   G TT
Sbjct: 1432 VSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKG--TEKTLPVPVVSLNIYDVGPTT 1489

Query: 717  ---PFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
                + P+           A+ +++S+    DT            E   P+ + L  T  
Sbjct: 1490 MHVQWQPVGG---------ATGYILSYKPVKDT------------EPTRPKEVRLGPTVN 1528

Query: 774  SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSR 833
             + + DL+P  +Y V V  +  D     +     T     P D  +  V  +++ V W  
Sbjct: 1529 DMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEP 1588

Query: 834  PQAPITGYRIVY-SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV 892
                +  Y + Y +P  +    E++  ET+ S  L DL     Y +++ AV +  ES PV
Sbjct: 1589 VPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS--LKDLFSQTLYTVSVSAVHDEGESPPV 1646

Query: 893  VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
              Q+ T        VP+P +L+  EVT       W    S V+ YR+   P     +   
Sbjct: 1647 TAQETTR------PVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 1700

Query: 953  RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----------PLTAQQTTKLDAPTN 1002
             L    NT      L+P   Y   + A+                 P+   Q  K   P N
Sbjct: 1701 ILNGDENTLV-FENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPK-SGPRN 1758

Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
            LQ  N T +++ V+W P   ++  YR+T    T  G  +   +G   +   L+ L+P + 
Sbjct: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818

Query: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-------EVTETTIVITWTPA---P 1111
            YT+++ ++  + E  + TG   T        P NT       + + +T+ + W  A   P
Sbjct: 1819 YTITVSSLYPDGEGGRMTGRGKT-------KPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871

Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSI---VVSGLTPGVEYVYTI-QVLRDGQE-RDAPI 1166
            R  +KL   P+ GG  P E+    G+    ++  L P   Y  T+  V  +G   R +  
Sbjct: 1872 R-QYKLFYAPAAGG--PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDT 1928

Query: 1167 VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
               ++  L+    ++   NP    L V W+ +  P +  YR+  +P +G + +    VV 
Sbjct: 1929 GRTLMRGLARNVQVY---NPTPNSLDVRWDPAPGP-VLQYRVVYSPVDGTRPSE-SIVVP 1983

Query: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--VPISDTIIPAVPPPTDLRFTNIGPDTMR 1284
             +      + L P   Y+V++  +  D E    P     +P    P +LR      +++ 
Sbjct: 1984 GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGETTNSLS 2042

Query: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1344
            V W       +  + + YSP   +      ++    N V+L  L P T Y ++V +VYE 
Sbjct: 2043 VAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYED 2101

Query: 1345 HESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1403
             +   L G  +T GL  P  I  SD     F V W    + + GY+I + P   S  P E
Sbjct: 2102 GDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG-SNEPME 2160

Query: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
              V     S TL NL P T Y V++ A      S  L  Q +T+     DL+       +
Sbjct: 2161 AFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDT 2219

Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523
              + W +P      YR+      G    QE TV GS+++   +GL P  DY +TV+  T 
Sbjct: 2220 FCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTVFVQTP 2277

Query: 1524 RGDSPASSKPISINYRTEIDKPSQ 1547
              + P     +S+   T + KP++
Sbjct: 2278 NLEGPG----VSVKEHTTV-KPTE 2296



 Score =  200 bits (508), Expect = 1e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542

Query: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584

Query: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642

Query: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702

Query: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758

Query: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818

Query: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938

Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991

Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049

Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105

Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222

Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280

Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
             P + + + +TV   P +      TP
Sbjct: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304



 Score =  184 bits (468), Expect = 6e-46
 Identities = 215/925 (23%), Positives = 375/925 (40%), Gaps = 86/925 (9%)

Query: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450

Query: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510

Query: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570

Query: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678

Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282
              A  +S    +L P   Y V+V    +D  S+P++  +T       P +L+ T+   D+
Sbjct: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738

Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342
             ++TW   P   +  + + Y PV   E   E++  P+     L NL+P T+Y VSV   Y
Sbjct: 739  FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796

Query: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
                 TPL G   T     +P  +  SD T ++  + W      +  Y + + P    G 
Sbjct: 797  FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855

Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458
             +E  V     +  L  L  GT+Y +S+ AL        L G+ +T+ +   P+DL    
Sbjct: 856  TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             T TS+   W +    VR YR+++     +    E  +P       I  L+P   Y I+V
Sbjct: 916  ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975

Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
            +A    G+     +P++ +  TE+ + S+ ++V +  +N++ V W P+   V  YRV   
Sbjct: 976  FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031

Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA 1634
            P +G G        P  T   ++ LQP   Y ++V      GE + L Q + TT     +
Sbjct: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089

Query: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694
            P +LK +  T +S    W P   ++ GY+V   P      + E+ + P  ++VV+  L  
Sbjct: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149

Query: 1695 ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGF 1754
             T Y+V+V+ + D   S P  G               +T  ++TT+     +  E +T  
Sbjct: 1150 GTTYKVNVFGMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRA 1196

Query: 1755 QVDAV-PANGQTPIQRTIKPDVRSY 1778
            + D V   +G   I R     VRS+
Sbjct: 1197 EADIVLLVDGSWSIGRANFRTVRSF 1221



 Score =  177 bits (449), Expect = 1e-43
 Identities = 148/554 (26%), Positives = 237/554 (42%), Gaps = 29/554 (5%)

Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510
            P+DL     T      +W      V  Y ITY E  G+  V     P S ++  +S LKP
Sbjct: 635  PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693

Query: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1568
               Y + V A    G     S P++    TE  K  P  ++VTD   +S  + W  +   
Sbjct: 694  ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749

Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
            V  YR+   P  G G ++  T  P+Q   T+E L P  +Y VSV  +  SG   PL   A
Sbjct: 750  VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808

Query: 1629 VTTIPA--PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSS 1686
             T      P DL+ +  T +++   W+    ++  Y V  TP    G  +E+ +  D+++
Sbjct: 809  ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAG-GETQEVTVRGDTTN 867

Query: 1687 VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRT 1746
             V+ GL   T+Y +SV AL  +       G  TTLE    P+     D T+T+I   W +
Sbjct: 868  TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927

Query: 1747 KTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1805
                + G++V            ++ +  D     I  LQP T Y+I ++    +    P+
Sbjct: 928  APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987

Query: 1806 VIDASTAIDAPSN-LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864
              DA+T +   S  L+    T N++ V+W+P   ++  Y + Y +P    +++V +  P 
Sbjct: 988  TGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPT 1046

Query: 1865 VTEATITGLEPGTEYTIYVIAL------KNNQKSEPLIGR------KKTGQEALSQTTIS 1912
            VT   +  L+P T Y I V+ +      K  Q S     R       KT    +S   ++
Sbjct: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106

Query: 1913 WAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--QQ 1969
            W P   +   Y ++ HP G D    +  V     +  L  L  G TY + V  + D  + 
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166

Query: 1970 RHKVREEVVTVGNS 1983
               V +E+ T+ ++
Sbjct: 1167 SPLVGQEMTTLSDT 1180



 Score =  161 bits (407), Expect = 7e-39
 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)

Query: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669

Query: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728

Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788

Query: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848

Query: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907

Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960

Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
              +NL P  +Y +SV+      E  P++ D           L+      +TMRVTW P P
Sbjct: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020

Query: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350
               + N+ V Y P  + ++ VA+  + P+  + VL  L P T Y ++V  +Y+  E    
Sbjct: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077

Query: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
            +G   T     SP  +  SD T +SF V W      + GY++  HP     R  E  V  
Sbjct: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137

Query: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449
              N++ L  L  GT Y V++  + +G E SPL+  + +T+SD
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179



 Score =  155 bits (391), Expect = 5e-37
 Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788

Query: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848

Query: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908

Query: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021

Query: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138

Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D      P+ 
Sbjct: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 2197

Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
            ++  T     T+L   +   DT    V W  S     T YR+  +P +G +G   E  V 
Sbjct: 2198 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 2251

Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
              ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 2252 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306



 Score =  147 bits (370), Expect = 1e-34
 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)

Query: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678

Query: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733

Query: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792

Query: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852

Query: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912

Query: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970

Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028

Query: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
               P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P DN VVL 
Sbjct: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
             L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181



 Score =  140 bits (352), Expect = 2e-32
 Identities = 176/796 (22%), Positives = 303/796 (38%), Gaps = 82/796 (10%)

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
            V PP++L    +    +++ W P PS  +T + V  +P+        LS+ P    + + 
Sbjct: 334  VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375
            +L   TEY +SVS++     S P+   +KT           G+D    I F  +   S++
Sbjct: 393  DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450

Query: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
            +   +++  RA     +  + I  +    S   +  R PH+    TL   T   + + +I
Sbjct: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHTE--FTLKKFTKVEDIIEAI 507

Query: 1429 VALNGREESP------------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476
                 R  S             + +  + + S+VP+ + ++    +S   ++  PA+ +R
Sbjct: 508  NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565

Query: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532
                       NS V+ F V      +S        P   +  TV      +  S   ++
Sbjct: 566  -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614

Query: 1533 PISINYRTEIDK--------PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584
             I +    E+          P  +  ++V        W P+   V  Y +T   K   G 
Sbjct: 615  SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672

Query: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV--QTAVTTIPAPTDLKFT 1641
             +     P   T + +  L+P   Y+V+V A+   G S PL   +T      AP +LK T
Sbjct: 673  DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732

Query: 1642 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1701
              T  S    WT    ++  YR+   P    G  +E+   P+     +  L+  TKYEVS
Sbjct: 733  DETTDSFKITWTQAPGRVLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVS 791

Query: 1702 VYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA 1761
            V     +    P  G   T E    PR  RV+D T +T+ +SW      +  + V   P 
Sbjct: 792  VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV 851

Query: 1762 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID--APSNL 1819
             G    + T++ D  +  + GL+ GT Y + +  L  +     +  + +T  +  +P +L
Sbjct: 852  AGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDL 911

Query: 1820 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1879
                 T  S+   W      + GY + ++                     I  L+P T+Y
Sbjct: 912  VTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKY 971

Query: 1880 TIYVIALKNNQKSEPLIG-----------RKKTGQEALSQTTISWAPFQ-DTSEYIISCH 1927
             I V A  ++ + EPL G             K  +E  +   ++W P       Y +   
Sbjct: 972  RISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031

Query: 1928 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 1987
            P G  ++ +  +VP T TS  L  L    TY+I V  +      K+R+   T  +     
Sbjct: 1032 PHGRGKQ-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSP 1090

Query: 1988 LNQPTDDSCFDPYTVS 2003
             N  T D     + V+
Sbjct: 1091 RNLKTSDPTMSSFRVT 1106



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73

Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133

Query: 917 EVT 919
            V+
Sbjct: 134 SVS 136



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 7/118 (5%)

Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82

Query: 1601 GLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653
             L P  EYVV++ + +   ES P+     +QT  +T P       T++   S+SA WT
Sbjct: 83   ELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSA-WT 139



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83

Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
            V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    +L+
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353
             L+P TEYVV+++S  E  ES P+ G+
Sbjct: 83   ELVPETEYVVTITSYDEVEESVPVIGQ 109



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83

Query: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 1624 LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75

Query: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1719
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372

Query: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 25/96 (26%), Positives = 44/96 (45%)

Query: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1865
            ++     ++ PSNL  +  +   + ++W P  + +TGY +      +  R+      P  
Sbjct: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386

Query: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1901
            T  ++  L   TEY I V A+K    SEP+   +KT
Sbjct: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74

Query: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130

Query: 1543 DKPSQMQVTDV 1553
             K S    TD+
Sbjct: 131  QKCSVSAWTDL 141



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 1813 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1872
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83

Query: 1873 LEPGTEYTIYVIALKNNQKSEPLIGR 1898
            L P TEY + + +    ++S P+IG+
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109



 Score = 36.2 bits (82), Expect = 0.36
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1705 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1763
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64

Query: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1806
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107



 Score = 36.2 bits (82), Expect = 0.36
 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)

Query: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1775
            +V+  E V PP      + +   + ++W      +TG++V   P   G      ++ P  
Sbjct: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386

Query: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1824
             + ++  L   T+Y+I +  +     S P           V ++ S  +D  +++ FL  
Sbjct: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446

Query: 1825 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1870
               S+ + ++   RA +   +  +E  P      +V   R   TE T+
Sbjct: 447  GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494



 Score = 35.0 bits (79), Expect = 0.80
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118



 Score = 33.5 bits (75), Expect = 2.3
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101

Query: 798 EQ-----SLILSTSQTTAP 811
           E       L + T  +T P
Sbjct: 102 ESVPVIGQLTIQTGSSTKP 120



 Score = 32.7 bits (73), Expect = 4.0
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
            ++S V     E+   L+  +  V + P +L  +  +   + ++W+     V  Y++    
Sbjct: 312  IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370

Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544
                S     +V    +T ++  L    +Y I+V A+ G      SS+PISI  +T+   
Sbjct: 371  MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423

Query: 1545 PSQMQV 1550
            P ++QV
Sbjct: 424  PMKVQV 429


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score =  306 bits (784), Expect = 1e-82
 Identities = 349/1581 (22%), Positives = 614/1581 (38%), Gaps = 266/1581 (16%)

Query: 616  ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
            +T T S P+S  + W  PQ S  S + ++++ ++  GR +   + G  +  T+ GL+PG 
Sbjct: 1378 LTVTGSSPDSLSLFWTVPQGSFDS-FTVQYKDRD--GRPRAVRVGGKESEVTVGGLEPGH 1434

Query: 676  VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734
             Y+  L     YG  E  R    +    + P    T     +P  P +    +VT++T +
Sbjct: 1435 KYKMHL-----YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGEL-TVTDVTPN 1488

Query: 735  SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
            S  +SW         F V+Y+  ++  +PQ + + +    V + +L P RKY +N+Y + 
Sbjct: 1489 SVGLSWTVPEGQFDSFIVQYK--DKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGL- 1545

Query: 795  EDGEQSLILSTSQTTAPDAPPDP----------------TVDQVDDTSIVVRWSRPQAPI 838
             DG++   LS    TAP  PP P                TV  +   S+ + W+ P+   
Sbjct: 1546 HDGQRMGPLSVVIVTAP-LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604

Query: 839  TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
              + + Y    +G    + +      VT+ DL+P  +Y   ++ +++ +  +PV ++ +T
Sbjct: 1605 DSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKT 1663

Query: 899  TGTPRSDTVPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
                 +     PR  +L   + T   + + WT PE     + V     + P    Q +P+
Sbjct: 1664 VARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGP----QVVPV 1719

Query: 957  S-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN------------- 1002
                    VT L  G  Y F ++ +   +   PLTA  TT+  +  +             
Sbjct: 1720 EGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLG 1779

Query: 1003 --LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
              LQ    T ++V + WT P  Q   + +     R GQP+   V  S+ +  +  L PA 
Sbjct: 1780 EELQVTTVTQNSVGLSWTVPEGQFDSFVVQYK-DRDGQPQVVPVEGSLREVSVPGLDPAH 1838

Query: 1061 EYT--------------VSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIV 1104
             Y               +S VAI  G +E+   T   T   P   +     E  T  T+ 
Sbjct: 1839 RYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLH 1898

Query: 1105 ITW--TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
            ++W  T      F++      G      +  D   I +SGL     Y+ T+    DG+  
Sbjct: 1899 LSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHV 1958

Query: 1163 -----DAPIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
                 +A  V +   P  PPT        P  G LTV+     TPD     ++ T   GQ
Sbjct: 1959 GPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVT---DATPD--SLSLSWTVPEGQ 2013

Query: 1217 QGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP 1265
              + L +  + D           +   T   L P  +Y +++Y     +   P+S   + 
Sbjct: 2014 FDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVT 2073

Query: 1266 AV----PPPTD----------------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
            A     P PT+                L  T   PD++ ++W  P      +F V+Y   
Sbjct: 2074 AAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQG-RFDSFTVQYKDR 2132

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG-----RQKTGLDS 1360
                 V    +   ++ V +  L PG +Y + +  ++E     P+        ++   D+
Sbjct: 2133 DGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDA 2190

Query: 1361 PTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
            P        +   DIT++S ++ W  P      + ++   ++  G+P+  RVP   + +T
Sbjct: 2191 PLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQF--KNGDGQPKAVRVPGHEDGVT 2248

Query: 1415 LTNLTPGTEYVVSIVALNGREE----------SPLLIGQQSTVSDVP-----------RD 1453
            ++ L P  +Y +++   +G +           +P    + +  S  P            +
Sbjct: 2249 ISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEE 2308

Query: 1454 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
            L V  ATP SL +SW  P     ++ + Y    G+   +   VPG +   TISGL+P   
Sbjct: 2309 LTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNK 2366

Query: 1514 YTITVYAVTG---------------RGDSPASSKPISINYRTEIDKP--SQMQVTDVQDN 1556
            Y + +Y   G                 ++P+ ++P S+      ++P   ++ VT    +
Sbjct: 2367 YKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP-SMEAPEPPEEPLLGELTVTGSSPD 2425

Query: 1557 SISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1616
            S+S+ W         +  T   K+  G  +    G +++E+T+ GL+P  +Y + +Y  +
Sbjct: 2426 SLSLSWTVPQGRFDSF--TVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLH 2483

Query: 1617 PSGESQPLVQTAVTT-------IPAPTD----------------LKFTQVTPTSLSAQWT 1653
                  P+    VT         P+PT+                L  T  +P SLS  WT
Sbjct: 2484 EGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWT 2543

Query: 1654 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1713
             P  +   + V+   K++ G  + + +    S V V GL    KY++ +Y L +     P
Sbjct: 2544 VPQGRFDSFTVQY--KDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGP 2601

Query: 1714 AQGVVTTLENVS-----------PPRRARV-----TDATETTITISWRTKTETITGFQVD 1757
               V  T +              PP + R+     TDAT  ++++SW         F V 
Sbjct: 2602 VSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQ 2661

Query: 1758 AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID--- 1814
                +GQ    R +       TI+GL+P   YK+ LY  +   R  P+ +   TA +   
Sbjct: 2662 YRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEET 2720

Query: 1815 ---------APS--------NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV 1857
                     AP          L    ++P+SL +SW  P+     + ++Y+     P+  
Sbjct: 2721 PSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQ-- 2778

Query: 1858 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK-------------------------- 1891
            V R R   +E T+ GLEPG +Y +++  L   ++                          
Sbjct: 2779 VMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPE 2838

Query: 1892 --SEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATL 1949
              ++P +G            ++SW   +   ++ +  +  G D +P   RVPG     T+
Sbjct: 2839 PPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKVVRVPGHEDGVTI 2897

Query: 1950 TGLTRGATYNIIVEALKDQQR 1970
            +GL     Y + +      QR
Sbjct: 2898 SGLEPDHKYKMNLYGFHGGQR 2918



 Score =  281 bits (718), Expect = 6e-75
 Identities = 336/1516 (22%), Positives = 584/1516 (38%), Gaps = 201/1516 (13%)

Query: 616  ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
            +T T S P+S  + W  PQ      + ++++ ++  GR +   + G  +  T++GL+PG 
Sbjct: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584

Query: 676  VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
             Y+  L  + + G +   V+    T     T     T+T E  P  P +    ++T+ T 
Sbjct: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641

Query: 734  SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
             S  +SW         F V+Y     GD +P+ + +P     V I  L P  KY +N+Y 
Sbjct: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698

Query: 793  I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
                   G  S+I  T+            T AP+ P +P + ++  T     S+ + W+ 
Sbjct: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758

Query: 834  PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
            PQ     + + Y    +G    + +    + VT+  L+PG +Y + +Y + E +   PV 
Sbjct: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817

Query: 893  ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
                        Q   T TP     P   +L   + T   +++ W  PE      + D  
Sbjct: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872

Query: 943  PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
             V      GQ    R+P        ++GL P   Y   ++    G+   P++    T  +
Sbjct: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931

Query: 999  ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
                APT                 L     +  ++ + WT P+ +   + +     R G+
Sbjct: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990

Query: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
            P+   V    S+  +  L+P  +Y               VS V +   ++  + T    T
Sbjct: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050

Query: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
            + P   I P   E+T T     ++ ++W  P  +   F +  R   G      V      
Sbjct: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110

Query: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
            + +SGL P  +Y   +     GQ R  P+    V +  TP   PT    EA      P  
Sbjct: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167

Query: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
            G LTV+    ++PD      T         T     + G      V  ++S  T   L P
Sbjct: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224

Query: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
            G +Y + +Y + + +   P+S         T +P  P   +L    +  D++ ++W    
Sbjct: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284

Query: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
                 +FLV+Y   + +     + +S    AV ++ L P  +Y   +  +       P+ 
Sbjct: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341

Query: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
               +T  D+        +  +D T +S  + W  P      + +++  +   GR +   V
Sbjct: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399

Query: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
              ++  +T+  L P  +Y   +  L+GR+    +    +T     ++P    +L V   T
Sbjct: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459

Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
             +SL +SW         + + Y +T G    +   V   + T T+  L+PG  Y   +Y 
Sbjct: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517

Query: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
            + G                 D+PA           E  +   + VTD   +S+ + W  +
Sbjct: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577

Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
              P   + V     NG  P      G DQ+++ I GL+P+  Y   +Y  +      PL 
Sbjct: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635

Query: 1626 -----------QTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------V 1666
                       QT+  + P  + L  T VT +SL   W  P      + +R        +
Sbjct: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695

Query: 1667 TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-S 1725
             P  +    +E+ +     S V+  L   T Y +++Y L+    +   QG   TL  V  
Sbjct: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755

Query: 1726 PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
             PR  + ++  ET+  ++W         F+V    A+G  P    +    R+  + GL P
Sbjct: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIP 3815

Query: 1786 GTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYII 1845
            G  Y++ + ++     S P+    +T  D P+ LR L  T    ++ W+PP+  +  Y +
Sbjct: 3816 GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 3875

Query: 1846 KYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQE 1904
            +   PG+PP +      PG   +  +  L   T YT  V  L+    + P      TG E
Sbjct: 3876 QVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLE 3932

Query: 1905 ALSQ----------TTISWA-PFQDTSEYIISCH-PVGTDEEPLQFRVPGTSTSATLTGL 1952
            A               ++W  P    + Y++S H P G ++E L   +PG  TS  L GL
Sbjct: 3933 APRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL---LPGGITSHQLLGL 3989

Query: 1953 TRGATYNIIVEALKDQ 1968
                +YN  ++A+  Q
Sbjct: 3990 FPSTSYNARLQAMWGQ 4005



 Score =  270 bits (690), Expect = 1e-71
 Identities = 354/1627 (21%), Positives = 621/1627 (38%), Gaps = 283/1627 (17%)

Query: 582  GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
            G +Y+   YG  +G+    PL        Q+ PS   P  +  +  T   P+S  + W  
Sbjct: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181

Query: 633  PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
            P+      +++++R ++  GR +   + G   S+ +  L P   Y   L  I   ++YG 
Sbjct: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237

Query: 690  QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
                    T   T+ P              PL+    +VT +T  S  +SW  A      
Sbjct: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290

Query: 750  FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
            F V+Y+ ++   +PQ + +      V +P L P RKY +N+Y +      G +S++  T+
Sbjct: 1291 FMVQYKDAQ--GQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348

Query: 807  Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
                           T AP++P +P + ++  T     S+ + W+ PQ     + + Y  
Sbjct: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408

Query: 848  SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
              +G    + +    + VT+  L+PG +Y + +Y + E Q   PV         Q+ET  
Sbjct: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
               S   P   +L   +VT   V + WT PE     +   ++         Q +P++ + 
Sbjct: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524

Query: 961  FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
              EVT   L P   Y   ++ +  G+   PL+            A + +K      L  +
Sbjct: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583

Query: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              TD T   V + WT P  +   + +     R GQP+   V     +  + +L+P+ +Y 
Sbjct: 1584 TVTDITPDSVGLSWTVPEGEFDSFVVQYK-DRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642

Query: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
              L  I+ G + SP +    T  +  +S   PP     + T+ T  ++ ++WT  P   F
Sbjct: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701

Query: 1116 KLGVRPSQGGEAPREVTSDSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT- 1172
               V   +  + P+ V  +    S+ V+ L  G +Y + +  L  G++R  P+     T 
Sbjct: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTTE 1760

Query: 1173 ------------PLSPPTNLHLEANPDT-GVLTVSWERSTTPD--ITGYRITTTPTNGQQ 1217
                        P  P     L+    T   + +SW   T P+     + +     +GQ 
Sbjct: 1761 ARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSW---TVPEGQFDSFVVQYKDRDGQP 1817

Query: 1218 GNSLEEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPIS-------------DT 1262
                 +VV  + S    +   L P   Y + +Y +   K   PIS             +T
Sbjct: 1818 -----QVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872

Query: 1263 IIPAVPPPT----DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
              P  P P     +L        T+ ++W      +  +F ++Y+    +  +  + I  
Sbjct: 1873 TAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEG-EFDSFEIQYTD--RDGQLQMVRIGG 1929

Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR------GRQKTGLDSPTG--------- 1363
              N + L+ L     Y+V++    +     P+         ++   + PT          
Sbjct: 1930 DRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPR 1989

Query: 1364 ---IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               +  +D T +S ++ W  P      + +++   +  G+P+  RVP     +T++ L P
Sbjct: 1990 LGELTVTDATPDSLSLSWTVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEEGVTISGLEP 2047

Query: 1421 GTEYV--------------VSIVALNGREES------PLLIGQQSTVSDVPRDLEVVAAT 1460
              +Y               VS+V +   EE       P +   +     +  +L V  ++
Sbjct: 2048 DHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSS 2107

Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
            P SL +SW  P      + + Y +  G   V    V G +S  T+ GL+PG  Y + +Y 
Sbjct: 2108 PDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYG 2165

Query: 1521 V-TGRGDSPASSKPISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
            +  GR   P S+  ++       D P       QM V D+  +S+S+ W         + 
Sbjct: 2166 LHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFL 2225

Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT-- 1631
            V    KNG G  K       +  +TI GL+P  +Y +++Y  +      P+    +T   
Sbjct: 2226 VQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPG 2283

Query: 1632 -----IPAPTD--------------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
                  PA T+              L  T  TP SLS  WT P  Q   + V+   K   
Sbjct: 2284 KDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGD 2341

Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT------------ 1720
            G  K   +      V +SGL    KY++++Y         P   +  T            
Sbjct: 2342 GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP 2401

Query: 1721 -LENVSPPRRA-----RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
             +E   PP         VT ++  ++++SW         F V     +G+  + R +  +
Sbjct: 2402 SMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2460

Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---------------IDAPS-- 1817
                T+ GL+PG  YK++LY L++  R  PV     TA                +AP   
Sbjct: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520

Query: 1818 ------NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
                   L    ++P+SL +SW  P+ R   + ++Y+     P+ V  R     ++ T+ 
Sbjct: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAV--RVGGQESKVTVR 2578

Query: 1872 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA---------------------LSQT- 1909
            GLEPG +Y +++  L   ++  P+     T  EA                     L+ T 
Sbjct: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638

Query: 1910 ------TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE 1963
                  ++SW   +   ++ +  +  G D +P   RVPG     T++GL     Y + + 
Sbjct: 2639 ATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 2697

Query: 1964 ALKDQQR 1970
                 QR
Sbjct: 2698 GFHGGQR 2704



 Score =  245 bits (625), Expect = 4e-64
 Identities = 338/1558 (21%), Positives = 583/1558 (37%), Gaps = 271/1558 (17%)

Query: 629  QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            +W  P P  +  Y +++ P          A +P   ++Y  +GL PG  Y+         
Sbjct: 768  EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ--------- 817

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
                VT      TS   P +    T    P          V  +T ++  + W+     V
Sbjct: 818  ----VTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
              F V Y  +  G++   L++P  A    + DL+PG +Y+V V         Y  S    
Sbjct: 868  DRFVVSYVSA--GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925

Query: 796  DGEQSL-ILSTSQTTAPDAPPDPTVDQV------------------DDTS-IVVRWSRPQ 835
             G   L +L T+    P  P      Q                   D+T  + V W+   
Sbjct: 926  TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985

Query: 836  APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QESTPVV 893
                 +++ +  P   G+  E+ LP       +    PG  Y ++++ V    + S P++
Sbjct: 986  DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044

Query: 894  IQ------QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVI 942
             Q      +E  G  +S   P   +L   + T   + + WT PE     + +     D  
Sbjct: 1045 YQGIMDKDEEKPG--KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102

Query: 943  PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTK 996
            P  +P E  QR  +       +T L PG  Y F ++     +   PL A      Q    
Sbjct: 1103 PQVVPVEGPQRSAV-------ITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPS 1155

Query: 997  LDAPT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
               P    NL   + T  ++ + WT P  Q   + +     R G+P+   V      + +
Sbjct: 1156 PGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-DRDGRPQVVPVEGPERSFVV 1214

Query: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTE 1100
             +L P  +Y  +L  I   +     T   TT       PP               T VT 
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274

Query: 1101 TTIVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             ++ ++WT A  P   F +  + +QG      V  D   + V GL P  +Y   +  LR 
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR- 1333

Query: 1159 GQERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDIT 1204
            G++R  P    VV   +P         PT L  EA      P  G LTV+    ++PD  
Sbjct: 1334 GRQRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSL 1388

Query: 1205 GYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
                T         T     + G      V   +S  T   L PG +Y + +Y + + + 
Sbjct: 1389 SLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQR 1448

Query: 1256 SVPISDTIIPA-----VPPPTD---------LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
              P+S   + A      PP T+         L  T++ P+++ ++W  P      +F+V+
Sbjct: 1449 VGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQ 1507

Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR---------- 1351
            Y     +  V  + ++     V + NL P  +Y +++  +++     PL           
Sbjct: 1508 YKDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565

Query: 1352 ----GRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
                   K  L+   G +  +DIT +S  + W  P      + +++      G+P+   V
Sbjct: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPV 1623

Query: 1407 PHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD------VPR--DLEVV 1457
               +  +T+ +L P  +Y   +  + +G+  SP+ +  ++           PR  +L V 
Sbjct: 1624 AADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVT 1683

Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
              TP SL +SW  P      + + + +  G   V    V G + + T++ L  G  Y   
Sbjct: 1684 DPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFL 1740

Query: 1518 VYAVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSS 1566
            +Y + G+      +   +   R+ +D        KP    ++QVT V  NS+ + W    
Sbjct: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800

Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
                 + V    ++G  P      G    E+++ GL P   Y + +Y  +      P+  
Sbjct: 1801 GQFDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISA 1858

Query: 1627 TAVT-------------TIPAPT----DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1669
             A+T             T PAP     +L   + T  +L   W     +   + ++ T +
Sbjct: 1859 VAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDR 1918

Query: 1670 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD----------TLT----SRPAQ 1715
            +  G ++ + +  D + + +SGL    +Y V++Y   D           LT     +P++
Sbjct: 1919 D--GQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976

Query: 1716 GVVTTLENVSPPRRAR--VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP 1773
                T E    PR     VTDAT  ++++SW         F V     +GQ    R +  
Sbjct: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVR-VPG 2035

Query: 1774 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA------------IDAPS---- 1817
                 TI+GL+P   YK+ LY  +   R  PV +   TA            ++AP     
Sbjct: 2036 HEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEE 2095

Query: 1818 ----NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1873
                 L    ++P+SL +SW  P+ R   + ++Y+     P+ V  R     +E T+ GL
Sbjct: 2096 PLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVV--RVGGEESEVTVGGL 2153

Query: 1874 EPGTEYTIYVIALKNNQKSEPL----------------IGRKKTGQEALSQTT-----IS 1912
            EPG +Y +++  L   ++  P+                + + + GQ  +   T     +S
Sbjct: 2154 EPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLS 2213

Query: 1913 WAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 1970
            W   +   ++ +     G D +P   RVPG     T++GL     Y + +      QR
Sbjct: 2214 WTVPEGQFDHFLVQFKNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2270



 Score =  243 bits (619), Expect = 2e-63
 Identities = 319/1439 (22%), Positives = 555/1439 (38%), Gaps = 244/1439 (16%)

Query: 738  VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
            V W +  DT + F++   + E G       LP       +P   PG  Y ++++ +   G
Sbjct: 979  VVWTAQPDTFAYFQLRMRVPE-GPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGG 1037

Query: 798  EQSLIL-----------STSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
            + S  +              +++ P    + TV      S+++RW+ P+     + I Y 
Sbjct: 1038 KPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK 1097

Query: 847  PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
               +G    + +     S  ++ L PG +Y   +Y     +   P+V + +    P+SD 
Sbjct: 1098 DR-DGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKIL--PQSDP 1154

Query: 907  VP-SPRDLQFVEVTDV---KVTIMWTPPESAVTGYRV-----DVIPVNLPGEHGQRLPIS 957
             P +P  L  + VTD     + + WT PE     + V     D  P  +P E  +R  + 
Sbjct: 1155 SPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFV- 1213

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT---KLDAPTNLQFVNE------ 1008
                  V+ L P   Y F +F +++ +   PLTA  TT   + + P   +F+ +      
Sbjct: 1214 ------VSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGEL 1267

Query: 1009 -----TDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
                 T  ++ + WT  +     + +      +GQP+   V    ++  +  L P  +Y 
Sbjct: 1268 TVTGVTPDSLRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGDENEVTVPGLDPDRKYK 1326

Query: 1064 VSLVAIKGNQ------------------ESPKATGVFTTLQPGSSIPPYNTEVTET---- 1101
            ++L  ++G Q                  E+P  T + T   P S   P   E+T T    
Sbjct: 1327 MNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEA-PESPEEPLLGELTVTGSSP 1385

Query: 1102 -TIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             ++ + WT        F +  +   G      V      + V GL PG +Y   +  L +
Sbjct: 1386 DSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHE 1445

Query: 1159 GQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
            GQ R  P+    VT        P T   LE  P  G LTV+     TP+  G  ++ T  
Sbjct: 1446 GQ-RVGPVSAVGVTAPQQEETPPATESPLE--PRLGELTVT---DVTPNSVG--LSWTVP 1497

Query: 1214 NGQ-----------QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
             GQ            G      V ADQ   T  NL P  +Y +++Y + D +   P+S  
Sbjct: 1498 EGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVV 1557

Query: 1263 IIPAVPPPT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
            I+ A  PP                +L  T+I PD++ ++W  P   +  +F+V+Y     
Sbjct: 1558 IVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDG 1616

Query: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG- 1363
            +  V  + ++     V + +L P  +Y   +  + +    +P+    KT   G  SP   
Sbjct: 1617 QPQV--VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAP 1674

Query: 1364 -----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
                 +  +D T +S  + W  P      + ++   +     P+   V     S+T+T L
Sbjct: 1675 PRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKD---GPQVVPVEGHERSVTVTPL 1731

Query: 1419 TPGTEYVVSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTS 1463
              G +Y   +  L G++    L        +S + D        PR   +L+V   T  S
Sbjct: 1732 DAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNS 1791

Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT- 1522
            + +SW  P      + + Y +  G   V    V GS    ++ GL P   Y + +Y +  
Sbjct: 1792 VGLSWTVPEGQFDSFVVQYKDRDGQPQV--VPVEGSLREVSVPGLDPAHRYKLLLYGLHH 1849

Query: 1523 GRGDSPASSKPISINYR---TEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVT 1570
            G+   P S+  I+       TE   P+         ++ V +   +++ + W+ +     
Sbjct: 1850 GKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD 1909

Query: 1571 GYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630
             + +  T ++G    +    G D+ ++T+ GL+    Y+V++Y  +      P+   A+T
Sbjct: 1910 SFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALT 1967

Query: 1631 T------------IPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
                          P P       +L  T  TP SLS  WT P  Q   + V+   +   
Sbjct: 1968 VPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGD 2025

Query: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP----- 1726
            G  K + +      V +SGL    KY++++Y         P   V VT  E  +P     
Sbjct: 2026 GQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEP 2085

Query: 1727 ----PRRAR--------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
                P  A         VT ++  ++++SW         F V     +G+  + R +  +
Sbjct: 2086 SMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2144

Query: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLA 1823
                T+ GL+PG  YK++LY L++  R  PV     TA      DAP        +    
Sbjct: 2145 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRD 2204

Query: 1824 TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIY 1882
             T +SL +SW  P  +   ++++++     P+ V VP    GV   TI+GLEP  +Y + 
Sbjct: 2205 ITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMN 2261

Query: 1883 VIALKNNQKSEPL--IGRKKTGQ----------------------EALSQT-------TI 1911
            +      Q+  P+  +G    G+                      E L+ T       ++
Sbjct: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSL 2321

Query: 1912 SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 1970
            SW   +   ++ +  +  G D +P   RVPG     T++GL     Y + +      QR
Sbjct: 2322 SWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379



 Score =  224 bits (570), Expect = 9e-58
 Identities = 271/1260 (21%), Positives = 479/1260 (38%), Gaps = 176/1260 (13%)

Query: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
            G    + VP+   ++   + +  V   WTP    V  Y +  IP           R+P S
Sbjct: 742  GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
             + + +  GL+PG  Y   V A+       P +   TT +D P +L+ V  T +T+ + W
Sbjct: 802  ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860

Query: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
              P+A++   R  V     G  R +  V P      L +L P  EY V++ A +G   S 
Sbjct: 861  LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918

Query: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
             A+          G+  T        P  T+  +  ++                      
Sbjct: 919  PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978

Query: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
            + WT  P     F+L +R  +G  A  EV   D    +V    PG  Y  ++  +  G +
Sbjct: 979  VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038

Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
               PI+ + +              P  G LTV+   S       T P+   +        
Sbjct: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097

Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPA 1266
             + G      V   Q S    +L PG +Y   +Y     K   P+             P 
Sbjct: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157

Query: 1267 VPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
             PP   +L  T+  PD++ ++W  P       F+V+Y        V  + +   + + V+
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVV 1214

Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITA 1371
            ++L P  +Y  ++  +  +    PL     T             L+ P    +  + +T 
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274

Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
            +S  + W   +     + +++  +   G+P+   V    N +T+  L P  +Y +++  L
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGL 1332

Query: 1432 NGREE--------------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISW 1468
             GR+                     SP  +G ++  S    +  +L V  ++P SL + W
Sbjct: 1333 RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFW 1392

Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDS 1527
              P  +   + + Y +  G    +   V G +S  T+ GL+PG  Y + +Y +  G+   
Sbjct: 1393 TVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450

Query: 1528 PASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
            P S+  ++   + E           +  ++ VTDV  NS+ + W         + V    
Sbjct: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510

Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT--IPAPT 1636
            K+  G  +      DQ E+T+  L+P  +Y +++Y  +      PL    VT    PAP 
Sbjct: 1511 KD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPA 1568

Query: 1637 -------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
                         +L  T +TP S+   WT P  +   + V+   K++ G  + + +A D
Sbjct: 1569 TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQVVPVAAD 1626

Query: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN-----VSPPRRAR--VTDAT 1736
               V +  L  + KY+  ++ ++D     P      T+        +PPR     VTD T
Sbjct: 1627 QREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPT 1686

Query: 1737 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
              ++ +SW         F V     +G  P    ++   RS T+T L  G  Y+  LY L
Sbjct: 1687 PDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744

Query: 1797 NDNARSSPVVIDAST----AID-----------APSNLRFLATTPNSLLVSWQPPRARIT 1841
                R  P+  D +T    A+D               L+    T NS+ +SW  P  +  
Sbjct: 1745 LGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFD 1804

Query: 1842 GYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL----- 1895
             ++++Y ++ G P  +VVP     + E ++ GL+P   Y + +  L + ++  P+     
Sbjct: 1805 SFVVQYKDRDGQP--QVVP-VEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAI 1861

Query: 1896 -IGRKKTGQEALSQTTISWAP------FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSAT 1948
              GR++T  E  + T  +  P       ++ + + +    + T+ E   F +  T     
Sbjct: 1862 TAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQ 1921

Query: 1949 LTGLTRGATYN-IIVEALKDQQRHKVREEVVTVGNSVN----EGLNQPTDDSCFDPYTVS 2003
            L  +  G   N I +  L+   R+ V     + G  V     E L  P ++   +P T +
Sbjct: 1922 LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTAT 1981



 Score =  188 bits (477), Expect = 6e-47
 Identities = 295/1387 (21%), Positives = 515/1387 (37%), Gaps = 245/1387 (17%)

Query: 822  VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN--LPETANSVTLSDLQPGVQYNIT 879
            +++T++   W+    P+  Y I + P+ EG+S      +P +A++     L PG +Y +T
Sbjct: 760  LEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT 819

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPS----PRDLQFVEVTDVKVTIMWTPPESAVT 935
            + A           ++  + G P S T+ +    P+DL+ V VT   + + W  P++ V 
Sbjct: 820  VRA-----------LRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVD 868

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTYYFKVFA-----------VSHG 983
             + V  +     G    RL +       + T L PGV Y   V A           V   
Sbjct: 869  RFVVSYVSA---GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925

Query: 984  RESKPLTAQQTTKLDAPTNLQFVNETDSTVL----------------------VRWTPPR 1021
              S PL    TT    P+         + +L                      V WT   
Sbjct: 926  TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985

Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
                 ++L + +       +  +   V +  +    P + Y +SL  +    + P    +
Sbjct: 986  DTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK-PSDPII 1044

Query: 1082 FTTL------QPG-SSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEA 1127
            +  +      +PG SS PP   E+T T     ++++ WT P      F +  +   G   
Sbjct: 1045 YQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ 1104

Query: 1128 PREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV-VTPLSPPTNLHLEANP 1186
               V     S V++ L PG +Y + +     G++R  P+V +  + P S P+       P
Sbjct: 1105 VVPVEGPQRSAVITSLDPGRKYKFVLYGFV-GKKRHGPLVAEAKILPQSDPSP---GTPP 1160

Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQ-----------QGNSLEEVVHADQSSCTFD 1235
              G L   W    TPD     ++ T   GQ            G      V   + S    
Sbjct: 1161 HLGNL---WVTDPTPD--SLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVS 1215

Query: 1236 NLSPGLEYNVSVYTVKDDKESVPIS--DTIIPA--VPPPT----------DLRFTNIGPD 1281
            +L P  +Y  +++ + + K   P++   T  P     PP           +L  T + PD
Sbjct: 1216 SLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPD 1275

Query: 1282 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP----------- 1330
            ++R++W         +F+V+Y   + +     + ++  +N V +  L P           
Sbjct: 1276 SLRLSWTVAQG-PFDSFMVQYKDAQGQPQA--VPVAGDENEVTVPGLDPDRKYKMNLYGL 1332

Query: 1331 ------GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG--------IDFSDITANSFTV 1376
                  G E VV+ ++  E  + TP     + G ++P          +  +  + +S ++
Sbjct: 1333 RGRQRVGPESVVAKTAPQEDVDETP--SPTELGTEAPESPEEPLLGELTVTGSSPDSLSL 1390

Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GRE 1435
             W  P+ +   + +++      GRPR  RV    + +T+  L PG +Y + +  L+ G+ 
Sbjct: 1391 FWTVPQGSFDSFTVQYKDR--DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQR 1448

Query: 1436 ESPL-LIG-----QQSTVSDVPRDLE-------VVAATPTSLLISWDAPAVTVRYYRITY 1482
              P+  +G     Q+ T       LE       V   TP S+ +SW  P      + + Y
Sbjct: 1449 VGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQY 1508

Query: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPAS----SKPISIN 1537
             +  G   V    V   +   T+  L+P   Y + +Y +  G+   P S    + P+   
Sbjct: 1509 KDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPA 1566

Query: 1538 YRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
              TE  KP       ++ VTD+  +S+ + W         + V    K+  G  +     
Sbjct: 1567 PATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQVVPVA 1624

Query: 1592 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI---------PAPTDLKFTQ 1642
             DQ E+TI  L+P+ +Y   ++         P+   A T           P   +L  T 
Sbjct: 1625 ADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTD 1684

Query: 1643 VTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV 1702
             TP SL   WT P  Q   + V+   K+K GP + + +     SV V+ L    KY   +
Sbjct: 1685 PTPDSLRLSWTVPEGQFDSFVVQF--KDKDGP-QVVPVEGHERSVTVTPLDAGRKYRFLL 1741

Query: 1703 YALKDTLTSRP--------AQGVVTTLENVSPPR-----RARVTDATETTITISWRTKTE 1749
            Y L       P        A+  +       PP+       +VT  T+ ++ +SW     
Sbjct: 1742 YGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEG 1801

Query: 1750 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1809
                F V     +GQ  +   ++  +R  ++ GL P   YK+ LY L+   R  P+   A
Sbjct: 1802 QFDSFVVQYKDRDGQPQVV-PVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860

Query: 1810 STAIDAPSNLRFLATTP-----------------NSLLVSWQPPRARITGYIIKY-EKPG 1851
             TA    +     A TP                 ++L +SW         + I+Y ++ G
Sbjct: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG 1920

Query: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTI--------------YVIAL---KNNQKSEP 1894
                  +   R    + T++GLE    Y +              +V AL   +  + SEP
Sbjct: 1921 QLQMVRIGGDR---NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEP 1977

Query: 1895 LIG------RKKTGQEALSQTT-----ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGT 1943
                     + + G+  ++  T     +SW   +   ++ +  +  G D +P   RVPG 
Sbjct: 1978 PTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGH 2036

Query: 1944 STSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG-NSVNEGLNQPTDDSCFDPYTV 2002
                T++GL     Y + +      QR      V  VG  +  E    PT+ S   P   
Sbjct: 2037 EEGVTISGLEPDHKYKMNLYGFHGGQR---MGPVSVVGVTAAEEETPSPTEPSMEAPEPA 2093

Query: 2003 SHYAVGD 2009
                +G+
Sbjct: 2094 EEPLLGE 2100


>gi|62988324 tenascin N [Homo sapiens]
          Length = 1299

 Score =  300 bits (767), Expect = 1e-80
 Identities = 236/826 (28%), Positives = 376/826 (45%), Gaps = 35/826 (4%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
            V +P+ LQ ++ T+  + + W P  S V  Y +   P+   L G+  Q +P  ++++ E+
Sbjct: 262  VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318

Query: 965  TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
             GL PG  Y   +  V +   S P     TT L         +ET++++ V W  P  ++
Sbjct: 319  LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
              Y+L  G     +  +  V  S    S+Y +  L P +EY +++V ++G  E  P    
Sbjct: 379  DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
              T +   +++      VTE T  ++W P   +  K  VR   + G      V  D  S 
Sbjct: 439  GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496

Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
            V++GL PG  Y   +   R  Q       N  +T +  P NL  +   +    T+SW+  
Sbjct: 497  VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                I  Y +  T  + Q+  + E +V  +QSS     L PG+EY V V+  K D+ES  
Sbjct: 554  VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611

Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
                    +  P +L    +  +   V+W P  +  +  ++VRY+    E    E+ +  
Sbjct: 612  ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668

Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
              ++ VLT L PG EY+V V +     ES     + +T +DSP  +    +T N  TV W
Sbjct: 669  EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728

Query: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
               RATI  Y +R+      G  RE  V   ++S  LT L PG EY V + A  G +ES 
Sbjct: 729  DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787

Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
                +  T  D P++L     T  +  +SWD    T+  Y + Y  T  N   +E  V  
Sbjct: 788  KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845

Query: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
             +S+  ++GL+PG++YT+ V+A  G  +    SK      +TEID P  +    V +N  
Sbjct: 846  EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901

Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
            +V W P  + +  Y V  T  +  G T+    G + +   + GL+P +EY+V V+AQ  +
Sbjct: 902  TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959

Query: 1619 GESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678
             ES+     A T +  P +L+ + VT +     WTPP+ Q+ GY   +T +   G +KE+
Sbjct: 960  QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGY--ILTYQFPDGTVKEM 1017

Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
             L  +     + GL     Y VS+ A K     R ++ V TTL  V
Sbjct: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKG---GRRSRNVSTTLSTV 1060



 Score =  296 bits (757), Expect = 2e-79
 Identities = 221/818 (27%), Positives = 369/818 (45%), Gaps = 28/818 (3%)

Query: 1082 FTTLQPGSSIPPYNTEV---TETTIVITWTPAPRIGFKLGVRPSQGGEAPR---EVTSDS 1135
            FT L     + P   ++   TE +++++W P+ ++   L      G E      +V  + 
Sbjct: 254  FTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313

Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
             S  + GL PG +Y+ T++ +++ +   +P      T L+      +    +   L V W
Sbjct: 314  HSYEILGLLPGTKYIVTLRNVKN-EVSSSPQHLLATTDLAVLGTAWVTDETENS-LDVEW 371

Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-QSSCTFDNLSPGLEYNVSVYTVKDDK 1254
            E  +T ++  Y++   P  GQ+   +     +D +S      L PG EY ++V  ++ + 
Sbjct: 372  ENPST-EVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGEL 430

Query: 1255 ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1314
            E  PI       +  PT++    +  DT  V+W P  ++ +  ++VRY+    + D  E+
Sbjct: 431  EGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAV-IDKYVVRYTSA--DGDTKEM 487

Query: 1315 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1374
            ++   +++ VLT L PG  Y V V +      S        T +DSP  +    +T N+ 
Sbjct: 488  AVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTA 547

Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
            T+ W   +ATI  Y +R+         RE  V   ++S  LT L PG EY V + A  G 
Sbjct: 548  TISWDPVQATIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGD 606

Query: 1435 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             ES        T  D P++L     T     +SWD     +  Y + Y   GG +  +E 
Sbjct: 607  RESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGET--REV 664

Query: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554
             V   +S+  ++GL+PG++Y + V+A  G  +S    K      +T+ID P  +    V 
Sbjct: 665  PVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQES----KKADTKAQTDIDSPQNLVTDRVT 720

Query: 1555 DNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1614
            +N  +V W P  + +  Y V  T     G T+    G +Q+   + GL+P VEY V V+A
Sbjct: 721  ENMATVSWDPVRATIDRYVVRYTSAKD-GETREVPVGKEQSSTVLTGLRPGVEYTVHVWA 779

Query: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
            Q  + ES+     A T I +P +L    VT  + +  W P    +  Y V  T     G 
Sbjct: 780  QKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGE 837

Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734
             +E+ +  + SS V++GL    +Y V V+A K    S+ A     T   +  P+      
Sbjct: 838  TREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDW 895

Query: 1735 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
             TE   T+SW     TI  + V    A+G+T  +  +  +  S  +TGL+PG +Y ++++
Sbjct: 896  VTENMATVSWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVW 954

Query: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1854
                   S      A T +D P NLR  A T +  +++W PP A+I GYI+ Y+ P    
Sbjct: 955  AQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTV 1014

Query: 1855 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
            +E+            + GLE G  Y + ++A K  ++S
Sbjct: 1015 KEMQLGRED--QRFALQGLEQGATYPVSLVAFKGGRRS 1050



 Score =  279 bits (713), Expect = 2e-74
 Identities = 207/721 (28%), Positives = 326/721 (45%), Gaps = 34/721 (4%)

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
            V  P  L+      D++ V+W P   +D  ++L+ Y P+  E    ++ +    ++  + 
Sbjct: 262  VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
             LLPGT+Y+V++ +V  +  S+P      T L        +D T NS  V W  P   + 
Sbjct: 320  GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379

Query: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
             Y++R+ P   +G+   E  VP S   ++   +T L PGTEY +++V + G  E   ++ 
Sbjct: 380  YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437

Query: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
               T  D P ++     T  +  +SWD     +  Y + Y    G++  +E  V   +S+
Sbjct: 438  NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495

Query: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
              ++GLKPG  Y + V+A  G       SK    N  TEID P+ +    V +N+ ++ W
Sbjct: 496  TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551

Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
             P  + +  Y V  T  +    T+    G +Q+   + GL+P VEY V V+AQ    ES+
Sbjct: 552  DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610

Query: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
                 A T I +P +L   +VT    +  W P    +  Y VR T     G  +E+ +  
Sbjct: 611  KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGK 668

Query: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1742
            + SS V++GL    +Y V V+A K    S+ A     T  ++  P+       TE   T+
Sbjct: 669  EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVTENMATV 726

Query: 1743 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1802
            SW     TI  + V    A      +  +  +  S  +TGL+PG +Y ++++       S
Sbjct: 727  SWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786

Query: 1803 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1862
                  A T ID+P NL     T N+  VSW P +A I  Y++ Y       REV     
Sbjct: 787  KKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKE 846

Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT---GQEAL-------SQTTIS 1912
               T   +TGL PG EYT++V A K NQ+S+    + +T   G + L       +  T+S
Sbjct: 847  QSST--VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVS 904

Query: 1913 WAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH 1971
            W P Q T  +Y++       D E  +  V    +S  LTGL  G  Y + V A K  Q  
Sbjct: 905  WDPVQATIDKYMV--RYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962

Query: 1972 K 1972
            K
Sbjct: 963  K 963



 Score =  240 bits (612), Expect = 1e-62
 Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +  Y+L + P       K+  +P   +SY I GL PG                  T++
Sbjct: 286  SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
              T  +    V+S+      T    ++ T+  VT+ T +S  V W + S  V  +++ Y 
Sbjct: 328  IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386

Query: 756  LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
                G E   + +P ++   +  +I  L PG +Y + V  +  + E   IL   +T   D
Sbjct: 387  -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444

Query: 813  APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
            +P +   D+V + +  V W   QA I  Y + Y+ S +G + E+ + +  +S  L+ L+P
Sbjct: 445  SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503

Query: 873  GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
            G  Y + ++A   NQ S       +   T     + SP +L    VT+   TI W P ++
Sbjct: 504  GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556

Query: 933  AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
             +  Y V     +   E  + L     +   +TGL PGV Y   V+A    RESK     
Sbjct: 557  TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615

Query: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
              T +D+P NL     T++   V W P +A I  Y +    +  G+ R+  VG   S   
Sbjct: 616  APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
            L  L+P  EY V + A KG+QES KA T   T +    ++      VTE    ++W P  
Sbjct: 675  LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732

Query: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
                +  VR   ++ GE  REV    +  S V++GL PGVEY   +   +  QE      
Sbjct: 733  ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             K  T +  P NL  +   +    TVSW+      I  Y +  T  NG+   + E  V  
Sbjct: 791  TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845

Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
            +QSS     L PG+EY V V+  K ++ES          +  P +L    +  +   V+W
Sbjct: 846  EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905

Query: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
              P    +  ++VRY+    E    E+ +    ++ VLT L PG EY+V V +     ES
Sbjct: 906  -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962

Query: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
                 + +T LD P  +  S +T +   + W  P A I GY + +  +   G  +E ++ 
Sbjct: 963  KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020

Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
                   L  L  G  Y VS+VA  G   S  +    STV
Sbjct: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060



 Score =  223 bits (567), Expect = 2e-57
 Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
            T    NS  ++W  P  + +  Y LR+ P        E T+P   +    Y I GL PG 
Sbjct: 360  TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417

Query: 676  VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
             Y+  ++ ++  G  E             P+  N   G T   SP    ++ VTE TA+ 
Sbjct: 418  EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460

Query: 736  FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
              VSW      +  + V Y  S +GD  + + +    +S  +  L PG  Y   VY  +E
Sbjct: 461  --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514

Query: 796  DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
             G Q S    T+  T  D+P +   D+V + +  + W   QA I  Y + Y+ + +  + 
Sbjct: 515  RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574

Query: 855  ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
            E+ + +  +S  L+ L+PGV+Y + ++A + ++ES     ++  T  P    + SP++L 
Sbjct: 575  EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627

Query: 915  FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
               VT+   T+ W P ++A+  Y   V+     G   + +P+ +   + V TGL PG+ Y
Sbjct: 628  TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684

Query: 974  YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
               V+A    +ESK    +  T +D+P NL     T++   V W P RA I  Y +    
Sbjct: 685  MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744

Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
             + G+ R+  VG   S   L  L+P  EYTV + A KG QES KA T   T +    ++ 
Sbjct: 745  AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803

Query: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
                 VTE T  ++W P      +  V  +      REV    +  S V++GL PG+EY 
Sbjct: 804  -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862

Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
              +   +  QE       K  T +  P NL  +   +  + TVSW+      I  Y +  
Sbjct: 863  VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919

Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
            T  +G+   + E  V  + SS     L PG+EY V V+  K  +ES          + PP
Sbjct: 920  TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976

Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
             +LR + +      +TW  PPS  +  +++ Y     +  V E+ +   D    L  L  
Sbjct: 977  RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033

Query: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
            G  Y VS+ +      S  +     T G   P   D S +  NS
Sbjct: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077



 Score =  216 bits (550), Expect = 2e-55
 Identities = 163/577 (28%), Positives = 261/577 (45%), Gaps = 32/577 (5%)

Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510
            P+ L+++  T  SLL+SW+ P+  V +Y ++Y   G     ++  VP  + +  I GL P
Sbjct: 265  PQGLQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLP 323

Query: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVT 1570
            G  Y +T+  V        SS P  +   T++       VTD  +NS+ V+W   S+ V 
Sbjct: 324  GTKYIVTLRNVKNE----VSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379

Query: 1571 GYRVTTTPKNGPGP---TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
             Y++   P  G      T  K++ P ++   I GL P  EY ++V       E +P++  
Sbjct: 380  YYKLRYGPMTGQEVAEVTVPKSSDP-KSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438

Query: 1628 AVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
              T I +PT++   +VT  + +  W P    +  Y VR T  +  G  KE+ +  D SS 
Sbjct: 439  GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESST 496

Query: 1688 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1747
            V++GL     Y+V V+A +    S+ A      L  +  P        TE T TISW   
Sbjct: 497  VLTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPV 554

Query: 1748 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
              TI  + V    A+ Q   +  +  +  S  +TGL+PG +Y ++++    +  S     
Sbjct: 555  QATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADT 614

Query: 1808 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
            +A T ID+P NL     T N   VSW P +A I  Y+++Y   G   REV        T 
Sbjct: 615  NAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST- 673

Query: 1868 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA----------LSQTTISWAPFQ 1917
              +TGL PG EY ++V A K +Q+S+    + +T  ++           +  T+SW P +
Sbjct: 674  -VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVR 732

Query: 1918 DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH-----K 1972
             T +  +  +    D E  +  V    +S  LTGL  G  Y + V A K  Q       K
Sbjct: 733  ATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792

Query: 1973 VREEVVTVGNSVNEGLNQPTDDSCFDPY--TVSHYAV 2007
             + ++ +  N V + + + T    +DP   T+  Y V
Sbjct: 793  AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV 829


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score =  281 bits (718), Expect = 6e-75
 Identities = 238/913 (26%), Positives = 398/913 (43%), Gaps = 39/913 (4%)

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 221  LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280

Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 281  KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338

Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 339  YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398

Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 399  TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453

Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 454  STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512

Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 513  HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570

Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 571  DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 631  NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 691  PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749

Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 750  VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806

Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P +
Sbjct: 807  VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866

Query: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696
            L+    T  SLS  W   +  +  YR+  +P     P+ E    P   ++V++  L   T
Sbjct: 867  LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 925

Query: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
             Y+++V A+ +        G   T+  + PP+   ++D   T   +SW      + G+++
Sbjct: 926  PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 984

Query: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816
               P     P++  +  ++ SYT+  L P T Y + +Y   D+  S P+    +T     
Sbjct: 985  VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043

Query: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876
            ++L+      ++  V W P RA  T Y +K   P    R      R   T    TGL P 
Sbjct: 1044 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 1101

Query: 1877 TEYTIYVIALKNN 1889
            T+Y + V     N
Sbjct: 1102 TDYGVTVFVQTPN 1114



 Score =  273 bits (698), Expect = 1e-72
 Identities = 243/934 (26%), Positives = 397/934 (42%), Gaps = 57/934 (6%)

Query: 909  SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGL 967
            +P +L   E T     + WTPP  +V  Y+V+  PV+  G   Q   +SR  T   +  L
Sbjct: 223  APSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS--GGKRQEFYVSRMETSTVLKDL 280

Query: 968  SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGY 1027
             P   Y   V++V     S+PL   + T      +L   +   +T+ V+W P     TGY
Sbjct: 281  KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TGY 339

Query: 1028 RLT---VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
             L+   V  T   +P++  +GP+V+   L +L P +EY V++ A+  +  S   T    T
Sbjct: 340  ILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVT 399

Query: 1085 LQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLT 1144
            L           +VT +T+ + W P P    K  VR     E  +EV  D      S   
Sbjct: 400  LPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKD 459

Query: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPD 1202
               + +YT+ V     E ++P V    T  P+  PTNL +      G    +W+   + D
Sbjct: 460  LFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEG-FRGTWDHGAS-D 517

Query: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE------- 1255
            ++ YRIT  P      + +E +++ D+++  F+NL+P   Y VS+  +  D+        
Sbjct: 518  VSLYRITWAPFGSS--DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 575

Query: 1256 ---SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
               ++PI  T  P    P +L+  N   +++ V W  P S  +  + + Y P   E +  
Sbjct: 576  SERTLPILTTQAPK-SGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGEGNEQ 633

Query: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITA 1371
              +I    N+VVL  L P T Y ++VSS+Y   E   + GR KT  L++   +   D + 
Sbjct: 634  TTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPST 693

Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            ++  V W         Y++ + P   +G P E   +P + N   L NL P T Y V++V 
Sbjct: 694  STLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVP 751

Query: 1431 LNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNS 1489
            +    +         T+   + R+++V   TP SL + WD     V  YR+ Y    G  
Sbjct: 752  VYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTR 811

Query: 1490 PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINYRTEIDKPS 1546
            P +   VPG+     +  L P   Y++ + A+   G+   SPA  + +  +       P 
Sbjct: 812  PSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS------GPR 865

Query: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1606
             ++V     NS+SV W  +  PV  YR+  +P  G    +  T    +  + ++ LQP  
Sbjct: 866  NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 925

Query: 1607 EYVVSVYAQNPSGESQPLVQTAVTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1665
             Y ++V A    G+   L     T  +  P ++  +    T     W P    + GY++ 
Sbjct: 926  PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 985

Query: 1666 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1725
              P     PM+      + +S  +  L  +T Y+V+VYA  D+  S P     TTL    
Sbjct: 986  YKPVGSNEPMEAF--VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY--- 1040

Query: 1726 PPRRARVTDATETTITISWRT------KTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
                  VTD    T  I W T           T +++   PA+G    + T++    S+ 
Sbjct: 1041 ----LNVTDLK--TYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHC 1094

Query: 1780 ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
             TGL P TDY + ++    N     V +   T +
Sbjct: 1095 FTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128



 Score =  262 bits (670), Expect = 2e-69
 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%)

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 222  EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 282  PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334

Query: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 335  GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390

Query: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 391  EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449

Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 450  RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509

Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 510  TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569

Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 570  SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626

Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 627  TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685

Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 686  LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743

Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 744  SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803

Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 804  YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863

Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 864  PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 923  PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978

Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 979  VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036

Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
             T     TDLK  Q+   +   +W+P     T YR++++P + T   +EI +    +S  
Sbjct: 1037 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 1094

Query: 1689 VSGLMVATKYEVSVY 1703
             +GL   T Y V+V+
Sbjct: 1095 FTGLSPDTDYGVTVF 1109



 Score =  260 bits (665), Expect = 9e-69
 Identities = 245/917 (26%), Positives = 400/917 (43%), Gaps = 67/917 (7%)

Query: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140
            PG    P N  ++E T     ++WTP       +K+   P  GG+     V+    S V+
Sbjct: 218  PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 277

Query: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P  EYV  +  V+ D  E   P+     T   P  +L++    D G  T+  +   
Sbjct: 278  KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 332

Query: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                TGY ++  P    +    +EV +    +     +L P  EY V+V  V  D  S P
Sbjct: 333  VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 392

Query: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
            ++  +  +P +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +
Sbjct: 393  VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 448

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375
              S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F 
Sbjct: 449  DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 508

Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
              W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E
Sbjct: 509  GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 567

Query: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486
             ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + 
Sbjct: 568  SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 627

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541
            G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP++      
Sbjct: 628  GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 682

Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
                  ++V D   ++++V+W  +      Y++   P  G GP +      +     +  
Sbjct: 683  ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 738

Query: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1658
            LQP   Y   VV VY +   G +    +T +  +    +++    TP SL  +W P    
Sbjct: 739  LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 796

Query: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1718
            +  YRV  +P + T P + I +  ++  V +  L+  T Y V++ AL       P+    
Sbjct: 797  VLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQG 856

Query: 1719 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
             TL   S PR  RV   T  +++++W      +  +++   P  G    + T  P  R+ 
Sbjct: 857  RTLPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNN 915

Query: 1779 TITG-LQPGTDYKIYLYTLNDNARSSPVVIDASTA-IDAPSNLRFLATTPNSLLVSWQPP 1836
             I   LQP T YKI +  + ++     +  +  T  +  P N+           VSW P 
Sbjct: 916  VILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPS 975

Query: 1837 RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL- 1895
             + + GY I Y+  GS   E +      +T  T+  L P T Y + V A  ++  S PL 
Sbjct: 976  PSPVLGYKIVYKPVGS--NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLT 1033

Query: 1896 ---------IGRKKTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRVPGTST 1945
                     +   KT Q       + W+P +  + Y +   P  GT  + +  R  G+ T
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVR--GSET 1091

Query: 1946 SATLTGLTRGATYNIIV 1962
            S   TGL+    Y + V
Sbjct: 1092 SHCFTGLSPDTDYGVTV 1108



 Score =  245 bits (625), Expect = 4e-64
 Identities = 225/833 (27%), Positives = 358/833 (42%), Gaps = 49/833 (5%)

Query: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
            + N V  P  L  P+NL +          VSW    +  +  Y++   P +G  G   E 
Sbjct: 211  LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
             V   ++S    +L P  EY V+VY+V +D+ S P+  T      P   L   ++GP TM
Sbjct: 267  YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326

Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
             V W P      T +++ Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V
Sbjct: 327  HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384

Query: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399
                 S P+  R+ T  L  P  +   D+T ++  V W      +  Y +R+  PE    
Sbjct: 385  LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
              +E  V  S  S +L +L   T Y VS+ A++   ESP +  Q++T     P +L++  
Sbjct: 442  DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             T      +WD  A  V  YRIT+   G +S   E  + G ++T     L P   Y +++
Sbjct: 502  VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560

Query: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
             A+    +   D   S + + I   T+  K  P  +QV +   NS++VKW P+S  V  Y
Sbjct: 561  TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-T 1631
            R+T  P  G G  +T T G  Q  + ++ L+P   Y ++V +  P GE   +     T  
Sbjct: 620  RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679

Query: 1632 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1691
            +    +L+    + ++L+ +W         Y++   P    GP + + +  +++  ++  
Sbjct: 680  LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRN 738

Query: 1692 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1751
            L   T Y V+V  +              TL      R  +V + T  ++ + W      +
Sbjct: 739  LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPV 797

Query: 1752 TGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810
              ++V   P +G  P +  + P + R   +  L P T Y + L  L  +   +P      
Sbjct: 798  LQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857

Query: 1811 T-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVT 1866
            T     P NLR    T NSL V+W      +  Y I Y      P +    VP  R  V 
Sbjct: 858  TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV- 916

Query: 1867 EATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-----------GQEALSQTTISWAP 1915
               +  L+P T Y I VIA+  +     L G  +T             E  ++  +SW P
Sbjct: 917  --ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDP 974

Query: 1916 F-QDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 1967
                   Y I   PVG++ EP++  V G  TS TL  L    TY++ V A  D
Sbjct: 975  SPSPVLGYKIVYKPVGSN-EPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYD 1025



 Score =  202 bits (515), Expect = 2e-51
 Identities = 238/984 (24%), Positives = 396/984 (40%), Gaps = 98/984 (9%)

Query: 599  CQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEAT 658
            C  ++       P  + I+E   +  S  + W  P  S + +Y + + P +  G+ +E  
Sbjct: 212  CNSVKGPGDLEAPSNLVISERTHR--SFRVSWTPPSDS-VDRYKVEYYPVSG-GKRQEFY 267

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTV--TGETT 716
            +     S  +K LKP   Y   + S+ +  + E  +   T  +   PV S  +   G TT
Sbjct: 268  VSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKG--TEKTLPVPVVSLNIYDVGPTT 325

Query: 717  ---PFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
                + P+           A+ +++S+    DT            E   P+ + L  T  
Sbjct: 326  MHVQWQPVGG---------ATGYILSYKPVKDT------------EPTRPKEVRLGPTVN 364

Query: 774  SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSR 833
             + + DL+P  +Y V V  +  D     +     T     P D  +  V  +++ V W  
Sbjct: 365  DMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEP 424

Query: 834  PQAPITGYRIVY-SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV 892
                +  Y + Y +P  +    E++  ET+ S  L DL     Y +++ AV +  ES PV
Sbjct: 425  VPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS--LKDLFSQTLYTVSVSAVHDEGESPPV 482

Query: 893  VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
              Q+ T        VP+P +L+  EVT       W    S V+ YR+   P     +   
Sbjct: 483  TAQETTR------PVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 536

Query: 953  RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----------PLTAQQTTKLDAPTN 1002
             L    NT      L+P   Y   + A+                 P+   Q  K   P N
Sbjct: 537  ILNGDENTLV-FENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPK-SGPRN 594

Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
            LQ  N T +++ V+W P   ++  YR+T    T  G  +   +G   +   L+ L+P + 
Sbjct: 595  LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654

Query: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-------EVTETTIVITWTPA---P 1111
            YT+++ ++  + E  + TG   T        P NT       + + +T+ + W  A   P
Sbjct: 655  YTITVSSLYPDGEGGRMTGRGKT-------KPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 707

Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSI---VVSGLTPGVEYVYTI-QVLRDGQE-RDAPI 1166
            R  +KL   P+ GG  P E+    G+    ++  L P   Y  T+  V  +G   R +  
Sbjct: 708  R-QYKLFYAPAAGG--PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDT 764

Query: 1167 VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
               ++  L+    ++   NP    L V W+ +  P +  YR+  +P +G + +    VV 
Sbjct: 765  GRTLMRGLARNVQVY---NPTPNSLDVRWDPAPGP-VLQYRVVYSPVDGTRPSE-SIVVP 819

Query: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--VPISDTIIPAVPPPTDLRFTNIGPDTMR 1284
             +      + L P   Y+V++  +  D E    P     +P    P +LR      +++ 
Sbjct: 820  GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGETTNSLS 878

Query: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1344
            V W       +  + + YSP   +      ++    N V+L  L P T Y ++V +VYE 
Sbjct: 879  VAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYED 937

Query: 1345 HESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1403
             +   L G  +T GL  P  I  SD     F V W    + + GY+I + P   S  P E
Sbjct: 938  GDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG-SNEPME 996

Query: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
              V     S TL NL P T Y V++ A      S  L  Q +T+     DL+       +
Sbjct: 997  AFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDT 1055

Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523
              + W +P      YR+      G    QE TV GS+++   +GL P  DY +TV+  T 
Sbjct: 1056 FCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTVFVQTP 1113

Query: 1524 RGDSPASSKPISINYRTEIDKPSQ 1547
              + P     +S+   T + KP++
Sbjct: 1114 NLEGPG----VSVKEHTTV-KPTE 1132



 Score =  200 bits (508), Expect = 1e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 323  PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378

Query: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 379  --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420

Query: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 421  FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478

Query: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 479  SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538

Query: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 539  NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594

Query: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 595  LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654

Query: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 655  YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 715  APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774

Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 775  NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827

Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 828  ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885

Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 886  GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941

Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 942  HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 999  VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058

Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116

Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
             P + + + +TV   P +      TP
Sbjct: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140



 Score =  155 bits (391), Expect = 5e-37
 Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 516  SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 572  DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624

Query: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 625  PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684

Query: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 685  NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744

Query: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 745  YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 799  QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857

Query: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 858  TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 918  LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974

Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D      P+ 
Sbjct: 975  SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 1033

Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
            ++  T     T+L   +   DT    V W  S     T YR+  +P +G +G   E  V 
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 1087

Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
              ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 1088 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  224 bits (572), Expect = 5e-58
 Identities = 227/838 (27%), Positives = 361/838 (43%), Gaps = 63/838 (7%)

Query: 902  PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN-----LPGEHGQRLPI 956
            P  D+  +PRDL   E +   + + WT     VTGY+V   P+      LP E  +    
Sbjct: 227  PPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVP 286

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLV 1015
            +  T   + GL P   Y   V A+      + ++   +TT L+ P  L   N T  ++LV
Sbjct: 287  AGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQNTTAHSLLV 345

Query: 1016 RW-TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE 1074
             W + P A  TGYR+T  +   G  +Q  +GP      LR+L+P ++Y V++  + G   
Sbjct: 346  AWRSVPGA--TGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSV 403

Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVT- 1132
             P AT +                +  T+I+++W   P   G++L  R   G E P++V  
Sbjct: 404  GP-ATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVL 462

Query: 1133 -SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP---IVNKVVTPLSPPTNLHLEANPDT 1188
             SD     + GL PG EY  T+  L +G E   P   +      P+SP T+L     P  
Sbjct: 463  PSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQ 522

Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
             V  VSW  S  P  T YRI    T G +      V+   Q++   D++  GL Y V V 
Sbjct: 523  RV-RVSW--SPVPGATQYRIIVRSTQGVERTL---VLPGSQTAFDLDDVQAGLSYTVRVS 576

Query: 1249 TVKDDKESVPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
                 +E      T+      P     LR        +RV W P P    + F + +S  
Sbjct: 577  ARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGFRISWSTG 634

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1364
               E  +  ++ P   A  +T L PGT Y V+VS +  + E        +T    P   +
Sbjct: 635  SGPE--SSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTV 692

Query: 1365 DFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
              +  +++S T+ W   P AT  GYR+  H  H  G  +   V        L  L P TE
Sbjct: 693  HVTQASSSSVTITWTRVPGAT--GYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTE 748

Query: 1424 YVVSIVA----LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1479
            Y V + A    ++G   S ++      V  V R L+++ A+   L I+W         YR
Sbjct: 749  YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSR-LQILNASSDVLRITW-VGVTGATAYR 806

Query: 1480 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
            + +G + G  P++   +PG+  +A I GL+ GV Y++ V A+ G  +      P+SI   
Sbjct: 807  LAWGRSEGG-PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT----PVSIVVT 861

Query: 1540 TEIDKP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            T  + P     + V    ++S+ ++W P      G+ +   P+ G    +++  GP+ + 
Sbjct: 862  TPPEAPPALGTLHVVQRGEHSLRLRWEPVPR-AQGFLLHWQPEGGQ--EQSRVLGPELSS 918

Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTDLKFTQVTPTSLSAQWTP 1654
              ++GL+P  +Y V +    P+GE      TA T  P     +L+    +  S++  WTP
Sbjct: 919  YHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTP 978

Query: 1655 PNVQLTGYRVRVTPKEKTGPMKEINLAPD-----SSSVVVSGLMVATKYEVSVYALKD 1707
             + + + Y +   P    GP +E+  +P      SSS  V+GL     Y  S+  + D
Sbjct: 979  VS-RASSYILSWRPLR--GPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLD 1033



 Score =  213 bits (541), Expect = 2e-54
 Identities = 225/847 (26%), Positives = 360/847 (42%), Gaps = 66/847 (7%)

Query: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLT-VGLTRRGQP-----RQ 1041
            P+T        AP +L     +  ++ V+WT     +TGY++    LT  GQP     ++
Sbjct: 223  PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282

Query: 1042 YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVF-TTLQPGSSIPPYNTEVTE 1100
             NV    +   LR L+P +EY V+++A+  N      +G   TT   G  +   NT  T 
Sbjct: 283  VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNT--TA 340

Query: 1101 TTIVITWTPAP-RIGFKLGVRPSQGGEAPR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             ++++ W   P   G+++  R   GG   + E+    GS+++  L PG +Y  T+  L  
Sbjct: 341  HSLLVAWRSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF- 399

Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQG 1218
            G+           T  S    L       T +L +SW  +  P+  GYR+      G + 
Sbjct: 400  GRSVGPATSLMARTDASVEQTLRPVILGPTSIL-LSW--NLVPEARGYRLEWRRETGLEP 456

Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP-----PPTDL 1273
               + V+ +D +    D L PG EY +++YT+ +  E V    T++P  P     P TDL
Sbjct: 457  PQ-KVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHE-VATPATVVPTGPELPVSPVTDL 514

Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGT 1332
            + T +    +RV+W+P P       +VR     + + V    + P S  A  L ++  G 
Sbjct: 515  QATELPGQRVRVSWSPVPGATQYRIIVR-----STQGVERTLVLPGSQTAFDLDDVQAGL 569

Query: 1333 EYVVSVSSVYEQHESTP----LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY 1388
             Y V VS+     E +     +R   +T L  P G+      A    V W  P    +G+
Sbjct: 570  SYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATRVRVAW-GPVPGASGF 627

Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP--LLIGQQST 1446
            RI       SG      +P    +  +T L PGT Y V++  L GREE P  +++ +   
Sbjct: 628  RISWSTG--SGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDP 685

Query: 1447 VSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
            +  V R + V  A+ +S+ I+W   P  T   YR+++    G  P +   V G  + A +
Sbjct: 686  LGPV-RTVHVTQASSSSVTITWTRVPGATG--YRVSWHSAHG--PEKSQLVSGEATVAEL 740

Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE---IDKPSQMQVTDVQDNSISVKW 1562
             GL+P  +YT+ V A     D P    P S+  RT    + + S++Q+ +   + + + W
Sbjct: 741  DGLEPDTEYTVHVRAHVAGVDGP----PASVVVRTAPEPVGRVSRLQILNASSDVLRITW 796

Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
            +  +   T YR+      G GP + +    +     I GL+  V Y V V A     E  
Sbjct: 797  VGVTG-ATAYRLAWGRSEG-GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT 854

Query: 1623 PL---VQTAVTTIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEI 1678
            P+   V T     PA   L   Q    SL  +W P P  Q  G+ +   P+   G  +  
Sbjct: 855  PVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEG--GQEQSR 910

Query: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738
             L P+ SS  + GL  AT+Y V +  L        A+    T     P    RV D +  
Sbjct: 911  VLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSID 970

Query: 1739 TITISWRTKTETITGFQVDAVPANG---QTPIQRTIKPDV-RSYTITGLQPGTDYKIYLY 1794
            ++T++W T     + + +   P  G   + P      P +  S  +TGL+PG  Y   L 
Sbjct: 971  SVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLT 1029

Query: 1795 TLNDNAR 1801
             + D  R
Sbjct: 1030 PVLDGVR 1036



 Score =  198 bits (503), Expect = 5e-50
 Identities = 212/811 (26%), Positives = 342/811 (42%), Gaps = 54/811 (6%)

Query: 1096 TEVTETTIVITWTPA--PRIGFKLGVRPSQGGEAP-----REVTSDSG--SIVVSGLTPG 1146
            +E +  ++ + WT A  P  G+K+   P  G   P     +EV   +G  S+ + GL P 
Sbjct: 241  SEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPL 300

Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY 1206
             EY  T+  L      +A       T L  P  L ++ N     L V+W   + P  TGY
Sbjct: 301  TEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQ-NTTAHSLLVAWR--SVPGATGY 356

Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA 1266
            R+T    +G  G + ++ +   Q S    +L PG +Y V+V T+         S      
Sbjct: 357  RVTWRVLSG--GPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTD 414

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
                  LR   +GP ++ ++W   P  +   + + +      E   ++ +        L 
Sbjct: 415  ASVEQTLRPVILGPTSILLSWNLVP--EARGYRLEWRRETGLEPPQKVVLPSDVTRYQLD 472

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITANSFTVHWIAPR 1382
             L PGTEY +++ ++ E HE         TG + P    T +  +++      V W +P 
Sbjct: 473  GLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSW-SPV 531

Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPL 1439
               T YRI        G  R   +P S+ +  L ++  G  Y V + A  G  E   S L
Sbjct: 532  PGATQYRIIVRSTQ--GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVL 589

Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
             + ++         L VV +  T + ++W  P      +RI++    G+ P    T+P  
Sbjct: 590  TVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWST--GSGPESSQTLPPD 646

Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSI 1558
             +   I+GL+PG  Y + V  + GR + PA+     I  RT+   P + + VT    +S+
Sbjct: 647  STATDITGLQPGTTYQVAVSVLRGREEGPAAV----IVARTDPLGPVRTVHVTQASSSSV 702

Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
            ++ W       TGYRV+    +  GP K++    + T   ++GL+P  EY V V A + +
Sbjct: 703  TITWTRVPG-ATGYRVSW--HSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRA-HVA 758

Query: 1619 GESQPLVQTAVTTIPAPTD----LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
            G   P     V T P P      L+    +   L   W       T YR+    + + GP
Sbjct: 759  GVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVT-GATAYRL-AWGRSEGGP 816

Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA-RVT 1733
            M+   L  ++ S  + GL     Y V V AL       P   VVTT     P      V 
Sbjct: 817  MRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVV 876

Query: 1734 DATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
               E ++ + W        GF +   P  GQ    R + P++ SY + GL+P T Y++ L
Sbjct: 877  QRGEHSLRLRWEPVPRA-QGFLLHWQPEGGQEQ-SRVLGPELSSYHLDGLEPATQYRVRL 934

Query: 1794 YTLNDNARSSPVVIDAST-AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPG 1851
              L          + A T +   PS  LR + T+ +S+ ++W P  +R + YI+ +    
Sbjct: 935  SVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPV-SRASSYILSWRPLR 993

Query: 1852 SPPREV--VPRPRPGVTEA-TITGLEPGTEY 1879
             P +EV   P+  PG++ +  +TGLEPG  Y
Sbjct: 994  GPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024



 Score =  196 bits (498), Expect = 2e-49
 Identities = 183/737 (24%), Positives = 311/737 (42%), Gaps = 49/737 (6%)

Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDV 1311
            VP++     +   P DL  +     ++RV W    S  +T + V+Y+P+         + 
Sbjct: 222  VPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSER 280

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
             E+++   + +V L  L P TEY V+V ++Y       + G  +T       +   + TA
Sbjct: 281  QEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTA 340

Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            +S  V W +     TGYR+       SG P ++  +   + S+ L +L PGT+Y V++  
Sbjct: 341  HSLLVAWRSVPGA-TGYRVTWRV--LSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVST 397

Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
            L GR   P       T + V + L  V   PTS+L+SW+      R YR+ +    G  P
Sbjct: 398  LFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNL-VPEARGYRLEWRRETGLEP 456

Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQV 1550
             Q+  +P   +   + GL+PG +Y +T+Y +    +    +  +       +   + +Q 
Sbjct: 457  PQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQA 516

Query: 1551 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
            T++    + V W P     T YR+    ++  G  +T      QT   ++ +Q  + Y V
Sbjct: 517  TELPGQRVRVSWSPVPG-ATQYRIIV--RSTQGVERTLVLPGSQTAFDLDDVQAGLSYTV 573

Query: 1611 SVYAQNPSGESQPLVQTA---VTTIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRV 1666
             V A+    E    V T      T  A   L+      T +   W P P    +G+  R+
Sbjct: 574  RVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGF--RI 629

Query: 1667 TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
            +    +GP     L PDS++  ++GL   T Y+V+V  L+      PA  +V   + + P
Sbjct: 630  SWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGR-EEGPAAVIVARTDPLGP 688

Query: 1727 PRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
             R   VT A+ +++TI+W T+    TG++V    A+G    Q  +  +     + GL+P 
Sbjct: 689  VRTVHVTQASSSSVTITW-TRVPGATGYRVSWHSAHGPEKSQ-LVSGEATVAELDGLEPD 746

Query: 1787 TDYKIYL---YTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGY 1843
            T+Y +++       D   +S VV  A   +   S L+ L  + + L ++W          
Sbjct: 747  TEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYR 806

Query: 1844 IIKYEKPGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPL------- 1895
            +      G P R  +    PG T+ A I GLE G  Y++ V AL  +++  P+       
Sbjct: 807  LAWGRSEGGPMRHQI---LPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTP 863

Query: 1896 ------IGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSA-T 1948
                  +G     Q       + W P      +++   P G  E   Q RV G   S+  
Sbjct: 864  PEAPPALGTLHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQE---QSRVLGPELSSYH 920

Query: 1949 LTGLTRGATYNIIVEAL 1965
            L GL     Y + +  L
Sbjct: 921  LDGLEPATQYRVRLSVL 937



 Score =  194 bits (494), Expect = 6e-49
 Identities = 220/875 (25%), Positives = 369/875 (42%), Gaps = 72/875 (8%)

Query: 696  DFTTTSTSTPVTSN----TVTGETTPFSPLVATSES----VTEITASSFVVSWVSASDTV 747
            DF+   T  P+ S     T  G      P  +TS      ++E ++ S  V W +AS  V
Sbjct: 200  DFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPV 259

Query: 748  SGFRVEYE-LSEEGD----EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
            +G++V+Y  L+  G     E Q +++P+  TSV +  L P  +Y V V  +  +     +
Sbjct: 260  TGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAV 319

Query: 803  LSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA 862
              T++TTA + P + T+      S++V W R     TGYR+ +     G + +  L    
Sbjct: 320  SGTARTTALEGP-ELTIQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQ 377

Query: 863  NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
             SV L DL+PG  Y +T+  +          +   T  +      P       V +    
Sbjct: 378  GSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-------VILGPTS 430

Query: 923  VTIMWTPPESAVTGYRVDVI-PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVS 981
            + + W     A  GYR++      L       LP S  T  ++ GL PG  Y   ++ + 
Sbjct: 431  ILLSWNLVPEA-RGYRLEWRRETGLEPPQKVVLP-SDVTRYQLDGLQPGTEYRLTLYTLL 488

Query: 982  HGRE-SKPLTAQQT---TKLDAPTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR 1036
             G E + P T   T     +   T+LQ        V V W+P P A  T YR+ V  T+ 
Sbjct: 489  EGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGA--TQYRIIVRSTQ- 545

Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS--SIPPY 1094
            G  R   +  S + + L ++Q    YTV + A  G +E   A+ +    +P +  ++P  
Sbjct: 546  GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRREPETPLAVPGL 604

Query: 1095 NTEVTETTIV-ITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
               V++ T V + W P P   GF++      G E+ + +  DS +  ++GL PG  Y   
Sbjct: 605  RVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVA 664

Query: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
            + VLR  +E  A ++     PL P   +H+     + V T++W R   P  TGYR++   
Sbjct: 665  VSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV-TITWTR--VPGATGYRVSWHS 721

Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP-- 1270
             +G + + L   V  + +    D L P  EY V V       +  P S  ++   P P  
Sbjct: 722  AHGPEKSQL---VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPAS-VVVRTAPEPVG 777

Query: 1271 --TDLRFTNIGPDTMRVTWAPPPSIDLTNFLV-RYSPVKNEEDVAELSISPSD-NAVVLT 1326
              + L+  N   D +R+TW     + +T     R +  ++E       I P + ++  + 
Sbjct: 778  RVSRLQILNASSDVLRITW-----VGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIR 832

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT---ANSFTVHWIAPRA 1383
             L  G  Y V V+++    E TP+     T  ++P  +    +     +S  + W  P  
Sbjct: 833  GLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRW-EPVP 891

Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
               G+ +   PE   G+ +   +    +S  L  L P T+Y V +  L    E P    +
Sbjct: 892  RAQGFLLHWQPE--GGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGP--SAE 947

Query: 1444 QSTVSDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGE---TGGNSPVQEFTV 1496
             +  ++ PR    +L VV  +  S+ ++W  P      Y +++      G   P    T+
Sbjct: 948  VTARTESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTL 1006

Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
            PG  S+  ++GL+PGV Y  ++  V      P +S
Sbjct: 1007 PGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEAS 1041



 Score =  191 bits (484), Expect = 9e-48
 Identities = 211/827 (25%), Positives = 351/827 (42%), Gaps = 58/827 (7%)

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL--- 1221
            P+        S P +L L + P +  L V W  ++ P +TGY++  TP  G  G  L   
Sbjct: 223  PVTRPPDDSTSAPRDLVL-SEPSSQSLRVQWTAASGP-VTGYKVQYTPLTGL-GQPLPSE 279

Query: 1222 --EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIG 1279
              E  V A ++S     L P  EY V+V  +  +     +S T         +L   N  
Sbjct: 280  RQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTT 339

Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
              ++ V W   P    T + V +  V +     +  + P   +V+L +L PGT+Y V+VS
Sbjct: 340  AHSLLVAWRSVPGA--TGYRVTWR-VLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVS 396

Query: 1340 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW-IAPRATITGYRIRHHPEHFS 1398
            +++ +          +T       +    +   S  + W + P A   GYR+    E   
Sbjct: 397  TLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGL 454

Query: 1399 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGRE-ESPLLI---GQQSTVSDVPRD 1453
              P++  +P       L  L PGTEY +++  L  G E  +P  +   G +  VS V  D
Sbjct: 455  EPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVT-D 513

Query: 1454 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
            L+        + +SW +P      YRI    T G    +   +PGS++   +  ++ G+ 
Sbjct: 514  LQATELPGQRVRVSW-SPVPGATQYRIIVRSTQGVE--RTLVLPGSQTAFDLDDVQAGLS 570

Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
            YT+ V A  G  +  AS   +     T +  P  ++V       + V W P     +G+R
Sbjct: 571  YTVRVSARVGPREGSASVLTVRREPETPLAVPG-LRVVVSDATRVRVAWGPVPG-ASGFR 628

Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP 1633
            ++ +   G GP  ++T  PD T   I GLQP   Y V+V       E    V  A T   
Sbjct: 629  ISWS--TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPL 686

Query: 1634 APT-DLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1691
             P   +  TQ + +S++  WT  P    TGYRV  +     GP K   ++ +++   + G
Sbjct: 687  GPVRTVHVTQASSSSVTITWTRVPGA--TGYRV--SWHSAHGPEKSQLVSGEATVAELDG 742

Query: 1692 LMVATKYEVSVYALKDTLTSRPAQGVVTTL-ENVSPPRRARVTDATETTITISWRTKTET 1750
            L   T+Y V V A    +   PA  VV T  E V    R ++ +A+   + I+W   T  
Sbjct: 743  LEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGA 802

Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810
             T +++    + G     + +  +  S  I GL+ G  Y + +  L  +   +PV I  +
Sbjct: 803  -TAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVT 861

Query: 1811 TAIDAP---SNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVT 1866
            T  +AP     L  +    +SL + W+P PRA+  G+++ ++  G   +  V  P   ++
Sbjct: 862  TPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEGGQEQSRVLGPE--LS 917

Query: 1867 EATITGLEPGTEYTIYVIAL--KNNQKSEPLIGRKKTGQ----------EALSQTTISWA 1914
               + GLEP T+Y + +  L       S  +  R ++ +           ++   T++W 
Sbjct: 918  SYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWT 977

Query: 1915 PFQDTSEYIISCHPV---GTDEEPLQFRVPGTSTSATLTGLTRGATY 1958
            P    S YI+S  P+   G +       +PG S+S  +TGL  G +Y
Sbjct: 978  PVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024



 Score =  180 bits (457), Expect = 1e-44
 Identities = 220/885 (24%), Positives = 367/885 (41%), Gaps = 86/885 (9%)

Query: 607  SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGR-----WKEATIPG 661
            S+S P ++ ++E  SQ  S  +QW A     ++ Y +++ P   +G+      +E  +P 
Sbjct: 231  STSAPRDLVLSEPSSQ--SLRVQWTAAS-GPVTGYKVQYTPLTGLGQPLPSERQEVNVPA 287

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
               S  ++GL+P   Y+  +I++      E       TT+   P                
Sbjct: 288  GETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP---------------- 331

Query: 722  VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
                 ++   TA S +V+W S     +G+RV + +   G   Q  +L     SV + DL 
Sbjct: 332  ---ELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVL-SGGPTQQQELGPGQGSVLLRDLE 386

Query: 782  PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV--DDTSIVVRWSR-PQAPI 838
            PG  Y V V  +     +S+  +TS     DA  + T+  V    TSI++ W+  P+A  
Sbjct: 387  PGTDYEVTVSTLF---GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEA-- 441

Query: 839  TGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE-STPVVIQQ 896
             GYR+ +          ++ LP       L  LQPG +Y +T+Y + E  E +TP  +  
Sbjct: 442  RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVP 501

Query: 897  ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
                 P S       DLQ  E+   +V + W+P   A T YR+ ++      E    LP 
Sbjct: 502  TGPELPVSPVT----DLQATELPGQRVRVSWSPVPGA-TQYRI-IVRSTQGVERTLVLPG 555

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----PLTAQQTTKLDAPTNLQFVNETDST 1012
            S+  F ++  +  G++Y  +V A    RE       +  +  T L  P  L+ V    + 
Sbjct: 556  SQTAF-DLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATR 613

Query: 1013 VLVRWTP-PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
            V V W P P A  +G+R++   T  G      + P  +   +  LQP + Y V++  ++G
Sbjct: 614  VRVAWGPVPGA--SGFRISWS-TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670

Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLGVRPSQGGEAPRE 1130
             +E P A  V  T   G     + T+ + +++ ITWT  P   G+++    + G E  + 
Sbjct: 671  REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730

Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP----IVNKVVTPLSPPTNLHLEANP 1186
            V+ ++    + GL P  E  YT+ V       D P    +V     P+   + L +  N 
Sbjct: 731  VSGEATVAELDGLEPDTE--YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQI-LNA 787

Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246
             + VL ++W   T    T YR+    + G  G    +++  +  S     L  G+ Y+V 
Sbjct: 788  SSDVLRITWVGVT--GATAYRLAWGRSEG--GPMRHQILPGNTDSAEIRGLEGGVSYSVR 843

Query: 1247 VYTVKDDKESVPISDTII--PAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
            V  +  D+E  P+S  +   P  PP    L     G  ++R+ W P P      FL+ + 
Sbjct: 844  VTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQ 901

Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG 1363
            P   +E    L   P  ++  L  L P T+Y V +S +    E        +T       
Sbjct: 902  PEGGQEQSRVL--GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPS 959

Query: 1364 IDFS--DITANSFTVHWIAPRATITGYRIRHHP-----EHFSGRPREDRVPHSRNSITLT 1416
            I+    D + +S T+ W  P +  + Y +   P     +   G P+   +P   +S  +T
Sbjct: 960  IELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQ--TLPGISSSQRVT 1016

Query: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1461
             L PG  Y+ S+  +      P     Q+ V   PR L  V   P
Sbjct: 1017 GLEPGVSYIFSLTPVLDGVRGPEASVTQTPV--CPRGLADVVFLP 1059



 Score =  159 bits (402), Expect = 3e-38
 Identities = 181/720 (25%), Positives = 287/720 (39%), Gaps = 66/720 (9%)

Query: 562  QDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPS 621
            +D E GT Y++  S              +GR +G       +T  S    VE  +     
Sbjct: 383  RDLEPGTDYEVTVST------------LFGRSVGPATSLMARTDAS----VEQTLRPVIL 426

Query: 622  QPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
             P S  + WN    +    Y L WR +  +   ++  +P  +  Y + GL+PG  Y   L
Sbjct: 427  GPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTL 484

Query: 682  ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             ++ + GH+            +TP T    TG   P SP+  T    TE+      VSW 
Sbjct: 485  YTLLE-GHE-----------VATPATV-VPTGPELPVSPV--TDLQATELPGQRVRVSW- 528

Query: 742  SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQ 799
            S     + +R+    S +G E + L LP + T+ ++ D+  G  Y V V       +G  
Sbjct: 529  SPVPGATQYRIIVR-STQGVE-RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586

Query: 800  SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
            S++    +   P A P   V   D T + V W  P    +G+RI +S    G  +   LP
Sbjct: 587  SVLTVRREPETPLAVPGLRVVVSDATRVRVAWG-PVPGASGFRISWSTG-SGPESSQTLP 644

Query: 860  ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVT 919
              + +  ++ LQPG  Y + +  +   +E    VI        R+D +   R +   + +
Sbjct: 645  PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVI------VARTDPLGPVRTVHVTQAS 698

Query: 920  DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
               VTI WT    A TGYRV     +  G    +L     T AE+ GL P   Y   V A
Sbjct: 699  SSSVTITWTRVPGA-TGYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTEYTVHVRA 755

Query: 980  VSHGRESKPLTAQQTT---KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRR 1036
               G +  P +    T    +   + LQ +N +   + + W       T YRL  G +  
Sbjct: 756  HVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG-ATAYRLAWGRSEG 814

Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
            G  R   +  +     +R L+    Y+V + A+ G++E    + V TT  P  + P   T
Sbjct: 815  GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTT--PPEAPPALGT 872

Query: 1097 ----EVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
                +  E ++ + W P PR  GF L  +P  G E  R +  +  S  + GL P  +Y  
Sbjct: 873  LHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRV 932

Query: 1152 TIQVLRD-GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
             + VL   G+   A +  +  +P  P   L +    DT + +V+   +     + Y ++ 
Sbjct: 933  RLSVLGPAGEGPSAEVTARTESPRVPSIELRV---VDTSIDSVTLAWTPVSRASSYILSW 989

Query: 1211 TPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP 1268
             P    GQ+     + +    SS     L PG+ Y  S+  V D       S T  P  P
Sbjct: 990  RPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCP 1049



 Score =  127 bits (320), Expect = 9e-29
 Identities = 127/478 (26%), Positives = 201/478 (42%), Gaps = 45/478 (9%)

Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1580
            V+ R  + A   P++         P  + +++    S+ V+W  +S PVTGY+V  TP  
Sbjct: 211  VSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLT 270

Query: 1581 G-----PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAP 1635
            G     P   +       +T + + GL+P  EY V+V A   +   + +  TA TT    
Sbjct: 271  GLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEG 330

Query: 1636 TDLKFTQVTPTSLSAQW-TPPNVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGL 1692
             +L     T  SL   W + P    TGYRV  RV      GP ++  L P   SV++  L
Sbjct: 331  PELTIQNTTAHSLLVAWRSVPGA--TGYRVTWRVL---SGGPTQQQELGPGQGSVLLRDL 385

Query: 1693 MVATKYEVSVYALKDTLTSRPAQGVVTTL---ENVSPPRRARVTDATETTITISWRTKTE 1749
               T YEV+V     TL  R + G  T+L    + S  +  R      T+I +SW    E
Sbjct: 386  EPGTDYEVTV----STLFGR-SVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPE 440

Query: 1750 TITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808
               G++++     G  P Q+ + P DV  Y + GLQPGT+Y++ LYTL +    +     
Sbjct: 441  A-RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATV 499

Query: 1809 ASTAIDAP----SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864
              T  + P    ++L+        + VSW P        II     G     V+P  +  
Sbjct: 500  VPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQ-- 557

Query: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA-------------LSQTTI 1911
             T   +  ++ G  YT+ V A    ++    +   +   E               ++  +
Sbjct: 558  -TAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRV 616

Query: 1912 SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 1969
            +W P    S + IS    G+  E  Q  +P  ST+  +TGL  G TY + V  L+ ++
Sbjct: 617  AWGPVPGASGFRIS-WSTGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score =  201 bits (510), Expect = 8e-51
 Identities = 184/688 (26%), Positives = 292/688 (42%), Gaps = 53/688 (7%)

Query: 795  EDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
            E+ ++ +  S    T P  P +    +V   S +V W+     +  YR+VY P+  G   
Sbjct: 339  EEQDREIKASAHAITGP--PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPD 396

Query: 855  ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
            E+ +  T +S  L +L    +Y I ++A+  +  S      +   GT  +  +P   DL 
Sbjct: 397  EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTAS------EGLRGTETTLALPMASDLL 450

Query: 915  FVEVTDVKVTIMWTPPESAVTGYRVDVIPV--NLPGEHGQRLPISRNTFAEVTGLSPGVT 972
              +VT+  + + W     A +GY +   P+   L G+  +      +T  E++GL P   
Sbjct: 451  LYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTE 509

Query: 973  YYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V+A+     S P+T Q+TT  L  P NL+  N   ++  + W P   QI GYR+  
Sbjct: 510  YTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVY 569

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                  +  +  V P ++ +PL+ L P +EYT+++ +I    +S   TGVFTT +  +  
Sbjct: 570  NNADGTEINEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQ 628

Query: 1092 PPYNTEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVE 1148
                 EVT  +  +TW P  A     KL   P  GG+    V   +  S V+ GL PG E
Sbjct: 629  YLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTE 688

Query: 1149 Y-VYTIQVLRDGQERDAPIV---------NKVVTPLSPPTNLH----------LEANPDT 1188
            Y V  + VL DG E +              +  T + P T++           +  +  T
Sbjct: 689  YEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETT 748

Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV-----VHADQSSCTFDNLSPGLEY 1243
              L V W+ S + D+  +R+T       QG+  EEV     V   Q++     L P  EY
Sbjct: 749  SSLRVKWDISDS-DVQQFRVTYMTA---QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804

Query: 1244 NVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             V+V  +  D E V +S     +P+   P +LR +    + +R+TW  PPS  +  + + 
Sbjct: 805  KVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITW-DPPSSPVKGYRIV 862

Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP 1361
            Y PV       E  +    N +++TNLL G +Y V + +      S  L G  KT     
Sbjct: 863  YKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGV 922

Query: 1362 TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR-EDRVPHSRNSITLTNLTP 1420
            T +    +   S   HW   R   T YR+    E    R + E  V           L P
Sbjct: 923  TNLQAKHVEMTSLCAHWQVHRHA-TAYRV--VIESLQDRQKQESTVGGGTTRHCFYGLQP 979

Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVS 1448
             +EY +S+       E P +   + T S
Sbjct: 980  DSEYKISVYTKLQEIEGPSVSIMEKTQS 1007



 Score =  194 bits (493), Expect = 8e-49
 Identities = 175/642 (27%), Positives = 289/642 (45%), Gaps = 49/642 (7%)

Query: 1096 TEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPREVTSDS--GSIVVSGLTPGVEYVY 1151
            +EVT  + ++ WT AP    K  V   P++GG+ P EV  D    S V+  L    EY  
Sbjct: 362  SEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGK-PDEVVVDGTVSSTVLKNLMSLTEYQI 420

Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
             +  +      +     +    L   ++L L    +   + V W+    P  +GY I   
Sbjct: 421  AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENS-MRVKWD--AVPGASGYLILYA 477

Query: 1212 P-TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVP 1268
            P T G  G+  E  +    +      L P  EY V+VY +  ++ S P++  +T + A+ 
Sbjct: 478  PLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL-ALS 536

Query: 1269 PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
            PP +LR +N+G ++ R+TW  P S  +  + + Y+     E + E+ + P      L  L
Sbjct: 537  PPRNLRISNVGSNSARLTW-DPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGL 593

Query: 1329 LPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRATITG 1387
             P TEY +++ S+Y++ +S PL G   T  + +   ++  ++T +SF V W    A    
Sbjct: 594  TPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGL 653

Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA-LNGREESPLLIGQQST 1446
            +++   P  + G+  E  +   ++S  +  L PGTEY VS++A L+   ES ++    +T
Sbjct: 654  HKLMWIPV-YGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTT 712

Query: 1447 VSD---------VP------------RDLEVVAATPTSLLISWDAPAVTVRYYRITYGET 1485
            +           VP            R+L V   T +SL + WD     V+ +R+TY   
Sbjct: 713  LDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTA 772

Query: 1486 GGNSPVQEFT----VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 1541
             G+ P +E      VPGS++   +  L P  +Y +TV  +   G+  + S P        
Sbjct: 773  QGD-PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAP---GKTLP 828

Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
               P  ++V++   N + + W P SSPV GYR+   P + PGPT     G D   + I  
Sbjct: 829  SSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITN 888

Query: 1602 LQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTG 1661
            L   ++Y V ++A   SG S  L     T     T+L+   V  TSL A W   +   T 
Sbjct: 889  LLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHW-QVHRHATA 947

Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1703
            YRV V    +    +E  +   ++     GL   ++Y++SVY
Sbjct: 948  YRV-VIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVY 988



 Score =  187 bits (474), Expect = 1e-46
 Identities = 230/987 (23%), Positives = 403/987 (40%), Gaps = 125/987 (12%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P  L++  ++   + I W  P     GY++ V P +  G+  Q    +  T A + G
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTATKAIIQG 88

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQ----------------------QTTKLDAPTNLQ 1004
            L P   Y  ++ A +  +ESKP   Q                        ++  +P  ++
Sbjct: 89   LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVK 148

Query: 1005 FVNET----DSTVLV--RWTPPRAQ-----------ITGYRLTVGLTRRGQPRQYNVGPS 1047
            FV +T    D  +LV   W+  R             +T + +    TR G   QY+  P 
Sbjct: 149  FVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLA-QYSGDPR 207

Query: 1048 VSKY------------PLRNLQPASEYTVSLVAIK---GNQESPKA---TGV------FT 1083
            +  +             +RNL      T++ +A+     N   P+A   TGV       T
Sbjct: 208  IEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILIT 267

Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGL 1143
              +    I P +  + E+ + +         F +GV+ +   E  +E+ S+  S  V  +
Sbjct: 268  DGKSQDDIIPPSRNLRESGVEL---------FAIGVKNADVNEL-QEIASEPDSTHVYNV 317

Query: 1144 TPGVEYVYTI------QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWER 1197
                + ++T+       +    +E+D  I         PPT L + +        V+W  
Sbjct: 318  AE-FDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL-ITSEVTARSFMVNWTH 375

Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
            +   ++  YR+   PT G  G   E VV    SS    NL    EY ++V+ +     S 
Sbjct: 376  APG-NVEKYRVVYYPTRG--GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASE 432

Query: 1258 PISDTIIP-AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN--EEDVAEL 1314
             +  T    A+P  +DL   ++  ++MRV W   P    + +L+ Y+P+      D  E+
Sbjct: 433  GLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEM 490

Query: 1315 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
             I  +   + L+ LLP TEY V+V +++ +  S P+ G++ T  L  P  +  S++ +NS
Sbjct: 491  KIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNS 550

Query: 1374 FTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
              + W      I GYRI ++  +  G    +       +  L  LTP TEY ++I ++  
Sbjct: 551  ARLTWDPTSRQINGYRIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYD 608

Query: 1434 REESPLLIGQQSTVSDVPRD--LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
              +S  L G  +T  +VP    LE+   T  S  ++W   +     +++ +    G    
Sbjct: 609  EGQSEPLTGVFTT-EEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGK-T 666

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-------------DSPASSKPISINY 1538
            +E  +   + +  I GL+PG +Y +++ AV   G             DS  +    +I  
Sbjct: 667  EEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVP 726

Query: 1539 RTEIDKPSQ-----MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK---TKTA 1590
             T +    Q     + V D   +S+ VKW  S S V  +RVT     G    +   T   
Sbjct: 727  TTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMV 786

Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA--PTDLKFTQVTPTSL 1648
               Q  + ++ L P  EY V+V      GE    V     T+P+  P +L+ ++     L
Sbjct: 787  PGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVS-VSAPGKTLPSSGPQNLRVSEEWYNRL 845

Query: 1649 SAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
               W PP+  + GYR+   P    GP  E  +  D ++++++ L+    Y V ++A + +
Sbjct: 846  RITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQAS 905

Query: 1709 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
              S    G+V TL       +A+  +   T++   W+      T ++V       +   +
Sbjct: 906  GFSDALTGMVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHA-TAYRVVIESLQDRQKQE 962

Query: 1769 RTIKPDVRSYTITGLQPGTDYKIYLYT 1795
             T+      +   GLQP ++YKI +YT
Sbjct: 963  STVGGGTTRHCFYGLQPDSEYKISVYT 989



 Score =  186 bits (472), Expect = 2e-46
 Identities = 181/672 (26%), Positives = 281/672 (41%), Gaps = 52/672 (7%)

Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPA 1059
            PT L     T  + +V WT     +  YR+    TR G+P +  V  +VS   L+NL   
Sbjct: 356  PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSL 415

Query: 1060 SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLG 1118
            +EY +++ AI  +  S    G  TTL    +      +VTE ++ + W   P   G+ + 
Sbjct: 416  TEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLIL 475

Query: 1119 VRP----SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT-P 1173
              P      G E   ++      I +SGL P  EY  T+  +  G+E   P+  +  T  
Sbjct: 476  YAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAM-FGEEASDPVTGQETTLA 534

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            LSPP NL + +N  +    ++W+  T+  I GYRI     N   G  + EV     ++  
Sbjct: 535  LSPPRNLRI-SNVGSNSARLTWD-PTSRQINGYRIV---YNNADGTEINEVEVDPITTFP 589

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTWAPPPS 1292
               L+P  EY ++++++ D+ +S P++       VP    L    +  D+ RVTW  P S
Sbjct: 590  LKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTW-HPLS 648

Query: 1293 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
             D     + + PV   +   E+ +    ++ V+  L PGTEY VS+ +V +    + +  
Sbjct: 649  ADEGLHKLMWIPVYGGK-TEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVT 707

Query: 1353 RQKTGLDS-------------------PTGID---FSDITANSFTVHWIAPRATITGYRI 1390
               T LDS                    TGI      D T +S  V W    + +  +R+
Sbjct: 708  AVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRV 767

Query: 1391 RHHPEHFSGRPRED-----RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
             +      G P E+      VP S+N++ L  L P TEY V++  +    E   +     
Sbjct: 768  TYMTA--QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGK 825

Query: 1446 TV-SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
            T+ S  P++L V       L I+WD P+  V+ YRI Y       P  E  V    +T  
Sbjct: 826  TLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTIL 885

Query: 1505 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP 1564
            I+ L  G+DY + ++A    G S A +  +    +T     + +Q   V+  S+   W  
Sbjct: 886  ITNLLSGMDYNVKIFASQASGFSDALTGMV----KTLFLGVTNLQAKHVEMTSLCAHW-Q 940

Query: 1565 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1624
                 T YRV           +  T G   T     GLQP  EY +SVY +    E  P 
Sbjct: 941  VHRHATAYRVVIESLQ-DRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEG-PS 998

Query: 1625 VQTAVTTIPAPT 1636
            V     T   PT
Sbjct: 999  VSIMEKTQSLPT 1010



 Score =  179 bits (455), Expect = 2e-44
 Identities = 174/702 (24%), Positives = 304/702 (43%), Gaps = 51/702 (7%)

Query: 1219 NSLEEVVHADQSS-----CTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
            N L+E+     S+       FD +   +E        + +++   I  +      PPT+L
Sbjct: 300  NELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL 359

Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
              + +   +  V W   P  ++  + V Y P +  +   E+ +  + ++ VL NL+  TE
Sbjct: 360  ITSEVTARSFMVNWTHAPG-NVEKYRVVYYPTRGGKP-DEVVVDGTVSSTVLKNLMSLTE 417

Query: 1334 YVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1392
            Y ++V ++Y    S  LRG + T  L   + +   D+T NS  V W A     +GY I +
Sbjct: 418  YQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SGYLILY 476

Query: 1393 HP--EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-D 1449
             P  E  +G  +E ++  +   I L+ L P TEY V++ A+ G E S  + GQ++T++  
Sbjct: 477  APLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALS 536

Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
             PR+L +      S  ++WD  +  +  YRI Y    G   + E  V    +T  + GL 
Sbjct: 537  PPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGLT 594

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ--MQVTDVQDNSISVKWLPSSS 1567
            P  +YTI ++++   G S    +P++  + TE + P+Q  +++ +V  +S  V W P S+
Sbjct: 595  PLTEYTIAIFSIYDEGQS----EPLTGVFTTE-EVPAQQYLEIDEVTTDSFRVTWHPLSA 649

Query: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
                +++   P  G G T+      +Q    IEGL+P  EY VS+ A    G    +V  
Sbjct: 650  DEGLHKLMWIPVYG-GKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTA 708

Query: 1628 AVTTI------PAPTDLKFTQVTP----------------TSLSAQWTPPNVQLTGYRVR 1665
              TT+      PA T +  T VT                 +SL  +W   +  +  +RV 
Sbjct: 709  VGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVT 768

Query: 1666 VTPKEKTGPMKEIN--LAPDS-SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1722
                +     + I   + P S +++++  L+  T+Y+V+V  +              TL 
Sbjct: 769  YMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLP 828

Query: 1723 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT-IKPDVRSYTIT 1781
            + S P+  RV++     + I+W   +  + G+++   P +   P   T +  D+ +  IT
Sbjct: 829  S-SGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILIT 887

Query: 1782 GLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARIT 1841
             L  G DY + ++    +  S  +     T     +NL+       SL   WQ  R   T
Sbjct: 888  NLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HAT 946

Query: 1842 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1883
             Y +  E      ++       G T     GL+P +EY I V
Sbjct: 947  AYRVVIESLQDRQKQ-ESTVGGGTTRHCFYGLQPDSEYKISV 987



 Score =  160 bits (404), Expect = 2e-38
 Identities = 156/663 (23%), Positives = 281/663 (42%), Gaps = 54/663 (8%)

Query: 729  TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIV 788
            +E+TA SF+V+W  A   V  +RV Y     G +P  + +  T +S  + +L+   +Y +
Sbjct: 362  SEVTARSFMVNWTHAPGNVEKYRVVY-YPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQI 420

Query: 789  NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPS 848
             V+ I        +  T  T A     D  +  V + S+ V+W       +GY I+Y+P 
Sbjct: 421  AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPL 479

Query: 849  VE---GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSD 905
             E   G   E+ + ET   + LS L P  +Y +T+YA+   + S PV  Q+ T       
Sbjct: 480  TEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL------ 533

Query: 906  TVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVT 965
             +  PR+L+   V      + W P    + GYR  ++  N  G     + +   T   + 
Sbjct: 534  ALSPPRNLRISNVGSNSARLTWDPTSRQINGYR--IVYNNADGTEINEVEVDPITTFPLK 591

Query: 966  GLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
            GL+P   Y   +F++    +S+PLT   TT ++ A   L+    T  +  V W P  A  
Sbjct: 592  GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFT 1083
              ++L       G+  +  +      + +  L+P +EY VSL+A+     ES   T V T
Sbjct: 652  GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711

Query: 1084 TL-----QPGSSIPPYNT---------------EVTETTIVITW--TPAPRIGFKLGVRP 1121
            TL     +P ++I P  +               + T +++ + W  + +    F++    
Sbjct: 712  TLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMT 771

Query: 1122 SQGGEAPRE-------VTSDSGSIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTP 1173
            +QG   P E       V     ++++  L P  EY  T+  +  DG+        K + P
Sbjct: 772  AQGD--PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTL-P 828

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
             S P NL + +      L ++W+  ++P + GYRI   P +   G +LE  V AD ++  
Sbjct: 829  SSGPQNLRV-SEEWYNRLRITWDPPSSP-VKGYRIVYKPVS-VPGPTLETFVGADINTIL 885

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
              NL  G++YNV ++  +    S  ++  +       T+L+  ++   ++   W      
Sbjct: 886  ITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHA 945

Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                 ++     + ++   E ++           L P +EY +SV +  ++ E   +   
Sbjct: 946  TAYRVVIESLQDRQKQ---ESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002

Query: 1354 QKT 1356
            +KT
Sbjct: 1003 EKT 1005



 Score =  148 bits (374), Expect = 5e-35
 Identities = 137/560 (24%), Positives = 232/560 (41%), Gaps = 52/560 (9%)

Query: 1447 VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
            ++  P +L     T  S +++W      V  YR+ Y  T G  P  E  V G+ S+  + 
Sbjct: 352  ITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKP-DEVVVDGTVSSTVLK 410

Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW--LP 1564
             L    +Y I V+A+       AS           +   S + + DV +NS+ VKW  +P
Sbjct: 411  NLMSLTEYQIAVFAIYAH---TASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVP 467

Query: 1565 SSSPVTGYRVTTTP--KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
             +S   GY +   P  +   G  K    G   T++ + GL P  EY V+VYA      S 
Sbjct: 468  GAS---GYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASD 524

Query: 1623 PLV-QTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681
            P+  Q     +  P +L+ + V   S    W P + Q+ GYR+     + T  + E+ + 
Sbjct: 525  PVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGT-EINEVEVD 583

Query: 1682 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1741
            P  ++  + GL   T+Y ++++++ D   S P  GV TT E V   +   + + T  +  
Sbjct: 584  P-ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTT-EEVPAQQYLEIDEVTTDSFR 641

Query: 1742 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
            ++W   +      ++  +P  G    +  +K +  S+ I GL+PGT+Y++ L  + D+  
Sbjct: 642  VTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGS 701

Query: 1802 SSPVVIDASTAIDA-------------------PSNLRFLAT---TPNSLLVSWQPPRAR 1839
             S VV    T +D+                    + +R L     T +SL V W    + 
Sbjct: 702  ESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSD 761

Query: 1840 ITGYIIKY-EKPGSPPREVVPRPR-PG-VTEATITGLEPGTEYTIYV---------IALK 1887
            +  + + Y    G P  EV+     PG      +  L P TEY + V         +++ 
Sbjct: 762  VQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVS 821

Query: 1888 NNQKSEPLIGRK--KTGQEALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTS 1944
               K+ P  G +  +  +E  ++  I+W  P      Y I   PV      L+  V    
Sbjct: 822  APGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADI 881

Query: 1945 TSATLTGLTRGATYNIIVEA 1964
             +  +T L  G  YN+ + A
Sbjct: 882  NTILITNLLSGMDYNVKIFA 901



 Score =  100 bits (248), Expect = 2e-20
 Identities = 130/581 (22%), Positives = 232/581 (39%), Gaps = 53/581 (9%)

Query: 624  NSHPIQWNAPQPSHISKYILRWRP--KNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
            NS  ++W+A   +  S Y++ + P  +   G  KE  I        + GL P   Y    
Sbjct: 457  NSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT--- 511

Query: 682  ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
                      VT +       S PVT    T   +P   L      ++ + ++S  ++W 
Sbjct: 512  ----------VTVYAMFGEEASDPVTGQETTLALSPPRNL-----RISNVGSNSARLTWD 556

Query: 742  SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSL 801
              S  ++G+R+ Y  + +G E   +++    T+  +  L P  +Y + ++ I ++G+   
Sbjct: 557  PTSRQINGYRIVYN-NADGTEINEVEV-DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEP 614

Query: 802  ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
            +     T    A     +D+V   S  V W    A    +++++ P   G + E+ L E 
Sbjct: 615  LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674

Query: 862  ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-----GTPRSDTVPSP------ 910
             +S  +  L+PG +Y +++ AV ++   + VV    TT       P +  VP+       
Sbjct: 675  QDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVF 734

Query: 911  ----RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH----GQRLPISRNTFA 962
                R+L   + T   + + W   +S V  +RV  +      E        +P S+N   
Sbjct: 735  QTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLL 794

Query: 963  EVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             +  L P   Y   V  +    E   ++A  +T     P NL+   E  + + + W PP 
Sbjct: 795  -LKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853

Query: 1022 AQITGYRLTV-GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            + + GYR+    ++  G   +  VG  ++   + NL    +Y V + A + +  S   TG
Sbjct: 854  SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913

Query: 1081 VFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSI- 1138
            +  TL  G +++   + E+  T++   W           V  S      +E T   G+  
Sbjct: 914  MVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTR 971

Query: 1139 -VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
                GL P  E  Y I V    QE + P V+ +    S PT
Sbjct: 972  HCFYGLQPDSE--YKISVYTKLQEIEGPSVSIMEKTQSLPT 1010



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 21/70 (30%), Positives = 36/70 (51%)

Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
           +   SI + W  P+    GY+++ +P+  G + +LNL  TA    +  L P   Y + I 
Sbjct: 41  ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQII 100

Query: 882 AVEENQESTP 891
           A  +++ES P
Sbjct: 101 AYNKDKESKP 110



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            ++  P++++   +  +SI + W        GY++  TP +G G T         T+  I+
Sbjct: 29   QVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQ 87

Query: 1601 GLQPTVEYVVSVYAQNPSGESQP 1623
            GL P   Y V + A N   ES+P
Sbjct: 88   GLMPDQNYTVQIIAYNKDKESKP 110



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 1/83 (1%)

Query: 1816 PSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1875
            P+ LR+   + +S+ +SW+ PR +  GY +    P S  +      +   T+A I GL P
Sbjct: 33   PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVT-PTSGGKTNQLNLQNTATKAIIQGLMP 91

Query: 1876 GTEYTIYVIALKNNQKSEPLIGR 1898
               YT+ +IA   +++S+P  G+
Sbjct: 92   DQNYTVQIIAYNKDKESKPAQGQ 114



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 21/81 (25%), Positives = 35/81 (43%)

Query: 1724 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1783
            V+PP R R    +  +I ISW+       G+++   P +G    Q  ++       I GL
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGL 89

Query: 1784 QPGTDYKIYLYTLNDNARSSP 1804
             P  +Y + +   N +  S P
Sbjct: 90   MPDQNYTVQIIAYNKDKESKP 110



 Score = 32.3 bits (72), Expect = 5.2
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 11/123 (8%)

Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
           I+  S  +SW +      G+++    +  G   Q L+L +TAT   I  L+P + Y V +
Sbjct: 41  ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTATKAIIQGLMPDQNYTVQI 99

Query: 791 YQISEDGEQSLILSTSQTTAPD----APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
              ++D E     +  Q    D      P P V  VD  +     SRP +P     +  +
Sbjct: 100 IAYNKDKESK--PAQGQFRIKDLEKRKDPKPRVKVVDRGN----GSRPSSPEEVKFVCQT 153

Query: 847 PSV 849
           P++
Sbjct: 154 PAI 156


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score =  159 bits (402), Expect = 3e-38
 Identities = 149/537 (27%), Positives = 234/537 (43%), Gaps = 31/537 (5%)

Query: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426

Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286
              +S    NL+   EY VSV+ + +      +   +  A +PPP  L    + P T+ +T
Sbjct: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486

Query: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342
            W P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+   
Sbjct: 487  WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542

Query: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
            E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G   
Sbjct: 543  EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600

Query: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461
            +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +     
Sbjct: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660

Query: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
             ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ A
Sbjct: 661  DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719

Query: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
                G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T  
Sbjct: 720  YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776

Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
            P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T  PA
Sbjct: 777  PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833



 Score =  148 bits (373), Expect = 7e-35
 Identities = 125/457 (27%), Positives = 200/457 (43%), Gaps = 19/457 (4%)

Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
            P +   +  +P PT L  + +   ++R++W P P   L   +V  +         E+ + 
Sbjct: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA--SRGGTPREVVVE 425

Query: 1318 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTV 1376
                +  L NL   TEY+VSV  +YE      LRG   T  L  P  +  + +T  +  +
Sbjct: 426  GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485

Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             W  P A  T Y +R  P    G   E  V   R  + L  L PG +Y VS+ +L G E 
Sbjct: 486  TW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544

Query: 1437 SPLL-IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQEF 1494
            S    I  ++     PR L     +  +  + W+     VR  R+TY    GG+S   E 
Sbjct: 545  SEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTE- 603

Query: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554
              PG+ ++AT+  L     YT+ V  +   G S   +  ++     +   PSQ+ +T++ 
Sbjct: 604  -APGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTK---KAPSPSQLSMTELP 659

Query: 1555 DNSISVKWLPSS-SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
             +++ + W+ ++ S V  Y++T TP  G G     +   +     + GL    EY V++ 
Sbjct: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718

Query: 1614 AQNPSG-ESQPL----VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668
            A    G  S P+      + V+  P P++L     TP SL   WTPP  ++  Y +   P
Sbjct: 719  AYYRDGARSDPVSLRYTPSTVSRSP-PSNLALASETPDSLQVSWTPPLGRVLHYWLTYAP 777

Query: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1705
                GP K +++    S V +  L  ATKY V V A+
Sbjct: 778  ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAI 814



 Score =  145 bits (367), Expect = 3e-34
 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)

Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130
            ++ P A     TL   +S+    ++VT ++I ++WTPAPR   K  +  R S+GG  PRE
Sbjct: 365  RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421

Query: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187
            V  +  + S  +  L    EY+ ++  + +G   +         PL PP  L L A  P 
Sbjct: 422  VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481

Query: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
            T  LT  W+ S     T Y +  +P +  +G   E  V   +     D L PG +Y VSV
Sbjct: 482  TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536

Query: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304
             +++  + S         P + PP  L F+++  D  RV W  AP P       LVR + 
Sbjct: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591

Query: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362
            V +E   +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+
Sbjct: 592  VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651

Query: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421
             +  +++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   
Sbjct: 652  QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710

Query: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
            TEY V+I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +
Sbjct: 711  TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770

Query: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
            Y +TY    G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 771  YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824



 Score =  127 bits (320), Expect = 9e-29
 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)

Query: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427

Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483

Query: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543

Query: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279
             +     + +S T   LS    Y V V  +     S  ++  +     P P+ L  T + 
Sbjct: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659

Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
             D +++ W       +  + + ++P+  E    E+S+  +    VL  L   TEY V++ 
Sbjct: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718

Query: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395
            + Y    + +   LR    T     P+ +  +  T +S  V W  P   +  Y + + P 
Sbjct: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778

Query: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443
               G  +   VP +R+ +TL +L   T+Y  +VS +   GR E+    GQ
Sbjct: 779  SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828



 Score =  115 bits (289), Expect = 4e-25
 Identities = 113/467 (24%), Positives = 202/467 (43%), Gaps = 23/467 (4%)

Query: 1451 PRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
            P  L +   T +S+ +SW  AP   ++Y  +     GG    +E  V G  ++  +  L 
Sbjct: 380  PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTP--REVVVEGPAASTELHNLA 437

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
               +Y ++V+ +   G        ++      +  P  + +  V   ++ + W PS+   
Sbjct: 438  SRTEYLVSVFPIYEGGVGEGLRGLVTT---APLPPPRALTLAAVTPRTVHLTWQPSAG-A 493

Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA-QNPSGESQPLVQTA 1628
            T Y V  +P +  G  + +     + E+ ++GL+P  +Y VSV + + P G     ++  
Sbjct: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRAR 553

Query: 1629 VTTIPAPTDLKFTQVTPTSLSAQW--TPPNVQLTGYRVRVTPKEKTGPMKEINLAP-DSS 1685
              T+  P  L F+ V+  +    W   P  V+L    VRVT     G       AP +++
Sbjct: 554  TPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL----VRVTYVSSEGGHSGQTEAPGNAT 609

Query: 1686 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745
            S  +  L  +T Y V V  L     S    G VTT +  SP + + +T+     + ++W 
Sbjct: 610  SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLS-MTELPGDAVQLAWV 668

Query: 1746 TKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNARSS 1803
                + +  +Q+   P       + ++  ++ +  + GL   T+Y + +     D ARS 
Sbjct: 669  AAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSD 728

Query: 1804 PVVI---DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY-EKPGSPPREVVP 1859
            PV +    ++ +   PSNL   + TP+SL VSW PP  R+  Y + Y    G  P + V 
Sbjct: 729  PVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVS 788

Query: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEAL 1906
             P    +  T+  L+  T+Y + V A+    +SE +    +T   AL
Sbjct: 789  VP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPAL 834



 Score =  104 bits (259), Expect = 1e-21
 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)

Query: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423

Query: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483

Query: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541

Query: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599

Query: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715

Query: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
            ++    +D   S P+S    P+     PP++L   +  PD+++V+W PP    + ++ + 
Sbjct: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774

Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
            Y+P         +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score =  102 bits (255), Expect = 3e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414

Query: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469

Query: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514

Query: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572

Query: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632

Query: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686

Query: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745

Query: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805

Query: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 96/367 (26%), Positives = 155/367 (42%), Gaps = 24/367 (6%)

Query: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
            Q  S    P    A+ T+PAPT L  +QVT +S+   WTP       Y + V    + G 
Sbjct: 360  QGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGT 418

Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734
             +E+ +   ++S  +  L   T+Y VSV+ + +       +G+VTT   + PPR   +  
Sbjct: 419  PREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAP-LPPPRALTLAA 477

Query: 1735 ATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793
             T  T+ ++W+      T + V   PA+ +    +R ++       + GL+PG DY++ +
Sbjct: 478  VTPRTVHLTWQPSAGA-THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536

Query: 1794 YTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKP 1850
             +L     S    I A T  +  P +L F   + ++  V W+  P   R+        + 
Sbjct: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEG 596

Query: 1851 GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR----KKTGQEAL 1906
            G   +   P      T AT+  L   T YT+ V  L     S  L GR    K      L
Sbjct: 597  GHSGQTEAP---GNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQL 653

Query: 1907 SQT-------TISW--APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 1957
            S T        ++W  A       Y I+  P+G + +  +  VPG   +A L GL R   
Sbjct: 654  SMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTE 712

Query: 1958 YNIIVEA 1964
            Y++ + A
Sbjct: 713  YDVTILA 719



 Score = 74.7 bits (182), Expect = 9e-13
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503

Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560

Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604

Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664

Query: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724

Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780

Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699

Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749

Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804

Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861

Query: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 111/525 (21%), Positives = 185/525 (35%), Gaps = 87/525 (16%)

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1551
            QE  +      AT+ GL P   YT+ ++ +TG G    + +              +  + 
Sbjct: 69   QEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARR--------------EFVIE 114

Query: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
            D++ +S+      SS    G          P PT + T  PD  + +    +P V +  S
Sbjct: 115  DLKSSSLD----RSSQRPLG-------SGAPEPTPSHTGSPDPEQAS----EPQVAFTPS 159

Query: 1612 VYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNV---QLTGYRVRVTP 1668
               + P+G     +       P P D+ F       +   W+  +    Q+  +   V  
Sbjct: 160  QDPRTPAGPQFRCLP------PVPADMVFL------VDGSWSIGHSHFQQVKDFLASVIA 207

Query: 1669 KEKTGPMK-EINLAPDSSSVVVSGLM--VATKYEVSV------YALKDTLTSRPAQGVVT 1719
              + GP K ++ L   S        +  ++TK +V        Y   +T T      V+ 
Sbjct: 208  PFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLG 267

Query: 1720 TLENVSPPRRARVTDATETTITISWRTKTETIT--------GFQVDAVPA-NGQTPIQRT 1770
              +N+ P    R   A    +    +++ +  T        G  V AV   N      R 
Sbjct: 268  --QNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRL 325

Query: 1771 IKPDVRSYTI--------TGLQPGTDYKIYLYTLNDNA-RSSPVVIDASTAIDAPSNLRF 1821
            +    R  T+         G   G   ++    L   + R  P    A   + AP++L  
Sbjct: 326  LASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVL 385

Query: 1822 LATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 1880
               T +S+ +SW P PR  +   I+     G  PREVV       TE  +  L   TEY 
Sbjct: 386  SQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTE--LHNLASRTEYL 443

Query: 1881 IYVIALKNNQKSEPLIGRKKTGQ---------EALSQTTI--SWAPFQDTSEYIISCHPV 1929
            + V  +      E L G   T            A++  T+  +W P    + Y++ C P 
Sbjct: 444  VSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPA 503

Query: 1930 GTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 1974
                E  +  V        L GL  G  Y + V++L+  +  + R
Sbjct: 504  SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
            precursor [Homo sapiens]
          Length = 1903

 Score =  152 bits (384), Expect = 3e-36
 Identities = 158/662 (23%), Positives = 272/662 (41%), Gaps = 70/662 (10%)

Query: 1367 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1424
            ++ TA S T+ W +     ++ Y I+H P++     +E D V  +R S+    L+P ++Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 389

Query: 1425 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1476
               +VA+N    G    P+L    +   S  PRD++    + T++L+ W   + P   ++
Sbjct: 390  EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 449

Query: 1477 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
             YR+ Y    T   +   +  V  S+ T TI  L P   Y++ V A T  GD P SS   
Sbjct: 450  GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
             I       +P   +     + SI + W  P S  +  Y +    K+G    + +     
Sbjct: 509  VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 566

Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA-----PTDLKFTQVTPTSL 1648
             T   ++GL+P   Y   + A++P G      + +  T+ +     P D+  T  + TS+
Sbjct: 567  GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 626

Query: 1649 SAQWTPPNVQ-----LTGYRVRVT--PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1701
               W PP V+     +T Y ++ T    E   P + + +  D++  ++  L   T+Y ++
Sbjct: 627  LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686

Query: 1702 VYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET-----ITG 1753
            V A  D      +  V + T E+V   PPR+  V     T++ +SWR+         I G
Sbjct: 687  VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746

Query: 1754 FQVDAV-----PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL---YTLNDNARSSPV 1805
            +QV  V        GQ  ++  +  D +   I+GLQP T Y + +    T  D ARS P 
Sbjct: 747  YQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPK 806

Query: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPP---RARITGYIIKYEKPGSPPREVVPRPR 1862
            ++  + A+     L    T  N+ L+ W PP      + GY +K+ +    P   +    
Sbjct: 807  LVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSE 866

Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQE--------------ALSQ 1908
                  T T +  G  Y   + A       E ++      +E                + 
Sbjct: 867  K-EDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTS 925

Query: 1909 TTISWAP------FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 1962
              +SW P          ++Y +    +     P++  +    T+ TLTGL    TY++ V
Sbjct: 926  VQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 985

Query: 1963 EA 1964
             A
Sbjct: 986  RA 987



 Score =  139 bits (351), Expect = 2e-32
 Identities = 228/1008 (22%), Positives = 390/1008 (38%), Gaps = 145/1008 (14%)

Query: 752  VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
            ++ E SEE D+ +Y  + + +         P   Y+  + ++     +  I  T+    P
Sbjct: 192  LQIEQSEESDQGKYECVATNSAGTRYS--APANLYVRELREVRRVPPRFSIPPTNHEIMP 249

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
                + T   V      V+W                  E  + E ++P   N + L+D++
Sbjct: 250  GGSVNITCVAVGSPMPYVKWML--------------GAEDLTPEDDMPIGRNVLELNDVR 295

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPP 930
                Y            ST  VI+     T ++  +P P     V E T   +T+ W   
Sbjct: 296  QSANYTCVAM-------STLGVIEAIAQITVKA--LPKPPGTPVVTESTATSITLTWDSG 346

Query: 931  ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESK 987
                  Y +         E  + +     T   V GLSP   Y F+V AV++   G  S+
Sbjct: 347  NPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSE 406

Query: 988  PLTAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR---AQITGYRL--TVGLTRR-GQP 1039
            P+  Q + +    AP ++Q    + +T+LV+W  P     QI GYR+  T+  T+     
Sbjct: 407  PVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNW 466

Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
             ++NV  S     + NL P   Y+V ++A     + P ++ +    Q G    P N +  
Sbjct: 467  MKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAE 525

Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
              +ET+I+++WTP PR      ++L  +  + GE  R       S  + GL P   Y + 
Sbjct: 526  PESETSILLSWTP-PRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFR 584

Query: 1153 IQVLRDGQERDAPIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD----I 1203
            +   R  Q   A             P +PP ++   +   T +L VSW+          I
Sbjct: 585  LAA-RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL-VSWQPPPVEKQNGII 642

Query: 1204 TGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPI 1259
            T Y I  T  +G+     E + + +D +    + L    EY ++V    D     ES+ +
Sbjct: 643  TEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSV 702

Query: 1260 SDTIIPAVP--PPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEEDVAE 1313
                   VP  PP  +    +   +++V+W +P P+     +  + V Y  ++N E   +
Sbjct: 703  LIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQ 762

Query: 1314 LSISPSDNA----VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG------ 1363
              +     A    ++++ L P T Y ++V++   + +      R K  L S TG      
Sbjct: 763  PMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGA----RSKPKLVSTTGAVPGKP 818

Query: 1364 -IDFSDITANSFTVHWIAPRAT---ITGYRIRHHPEHFSGRPREDRVP-------HSRNS 1412
             +  +    N+  + W  P  T   + GYR++          R+D  P          + 
Sbjct: 819  RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG--------RKDMEPLTTLEFSEKEDH 870

Query: 1413 ITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1468
             T T++  G  YV  + A N    G E    +   +   +  P++L     T TS+ +SW
Sbjct: 871  FTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSW 930

Query: 1469 DAPAVTVRY-----YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1522
              P +  R      Y + Y +      P+++  VP   +T T++GLKP   Y + V A T
Sbjct: 931  QPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPAD-TTMTLTGLKPDTTYDVKVRAHT 989

Query: 1523 GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGP 1582
             +G  P S    S+ +RT       + V  V   +  VK +  +S +  + +   P+N  
Sbjct: 990  SKGPGPYSP---SVQFRT-------LPVDQVFAKNFHVKAVMKTSVLLSWEI---PENYN 1036

Query: 1583 GPTKTKTAGPD----------QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
                 K    D           T+  I  L+P   Y    +     G S   +Q  VT  
Sbjct: 1037 SAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSY---SFVLTNRGNSAGGLQHRVTAK 1093

Query: 1633 PAPTDL--KFTQVTPTSLSAQWT------PPNVQLTGYRVRVTPKEKT 1672
             AP  L  K   +  T+L    T      P N  + GY + + P +K+
Sbjct: 1094 TAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKS 1141



 Score =  131 bits (330), Expect = 6e-30
 Identities = 158/701 (22%), Positives = 294/701 (41%), Gaps = 72/701 (10%)

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
            ++T  + ST      +   T    P    +  VTE TA+S  ++W S + + VS + +++
Sbjct: 299  NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 358

Query: 755  ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
            +   +  E  Y ++   AT+  ++  L P   Y   V  ++  G     + ++  TS+  
Sbjct: 359  K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 416

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
               AP D     +  T+I+V+W  P+ P   I GYR+ Y+  P+   ++   +    +  
Sbjct: 417  PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 476

Query: 865  VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
             T+ +L P   Y++ + A   + +   S+ + VI Q  TG P       P + +    ++
Sbjct: 477  TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 529

Query: 921  VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
              + + WTPP S  +  Y +    V   GEHG  QR+ I   T   + GL P   YYF++
Sbjct: 530  TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 585

Query: 978  FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
             A S    G  +  ++A+  Q+     P ++   + + +++LV W PP  +     IT Y
Sbjct: 586  AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645

Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
              + T       +P +    PS  +KY L  L+  +EY +++ A       P++  V   
Sbjct: 646  SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 705

Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEAPRE--- 1130
            T +   S PP   E   V  T++ ++W +P P        G+++     + GE   +   
Sbjct: 706  TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765

Query: 1131 ---VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEA 1184
               + +D+  +++SGL P   Y  T+       DG      +V+        P  +    
Sbjct: 766  KDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHT 825

Query: 1185 NPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
              +T ++       T   + GYR+     + +   +LE     D  + T  +      + 
Sbjct: 826  QMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR 885

Query: 1245 VSVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
            +S        E + + +  IP   P   P +L        +++++W PP   +    + +
Sbjct: 886  LSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITK 944

Query: 1302 YSPVKNEEDV----AELSISPSDNAVVLTNLLPGTEYVVSV 1338
            Y+ +  + ++     E  I P+D  + LT L P T Y V V
Sbjct: 945  YTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 985



 Score =  105 bits (263), Expect = 4e-22
 Identities = 156/688 (22%), Positives = 258/688 (37%), Gaps = 93/688 (13%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
            T S   S  + W++  P  +S YI++ +PKNS   +KE  I G   + Y++ GL P   Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 389

Query: 678  EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
            E +++++   G              S PV   T T E  P S           +++++ +
Sbjct: 390  EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 435

Query: 738  VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
            V W    +    + G+RV Y +        ++      + +  I +L+P + Y V V   
Sbjct: 436  VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 495

Query: 794  SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
            +  G+  L   I   +QT  P  P +   +   +TSI++ W+ P++  I  Y +VY    
Sbjct: 496  TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 555

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
             G    + + E   S  L  L+P   Y   + A   + +       + +  T +S     
Sbjct: 556  HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 612

Query: 910  PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
            P+D+     +   + + W PP        +T Y +    V+  GE  +          E+
Sbjct: 613  PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 662

Query: 965  TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
             G+    T Y          +++   +H   G   + L+    T  D P+       ++ 
Sbjct: 663  LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 722

Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV-----SKYPLRN 1055
            VN T  +V V W  P       QI GY++       G+P+   +   V         +  
Sbjct: 723  VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISG 780

Query: 1056 LQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTIVITWTP--- 1109
            LQP + Y  TV+    KG+    K   V TT   PG      N      T +I W P   
Sbjct: 781  LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTALIQWHPPVD 839

Query: 1110 --APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERD 1163
               P  G++L   R         E +        + +  G  YV+ +        G+E  
Sbjct: 840  TFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMV 899

Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGN 1219
              I      P   P NLH E    T V  +SW+     +    IT Y +     N     
Sbjct: 900  KEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLYRDINIPLLP 958

Query: 1220 SLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
              + +V AD ++ T   L P   Y+V V
Sbjct: 959  MEQLIVPAD-TTMTLTGLKPDTTYDVKV 985



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 75/332 (22%), Positives = 131/332 (39%), Gaps = 43/332 (12%)

Query: 1708 TLTSRPAQGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVP 1760
            T  +    GV+  +  ++      PP    VT++T T+IT++W +   E ++ + +   P
Sbjct: 301  TCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKP 360

Query: 1761 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVIDAS--TAIDA 1815
             N +   +         Y++ GL P +DY+  +  +N+  R   S PV+   S      A
Sbjct: 361  KNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSA 420

Query: 1816 PSNLRFLATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT- 1871
            P +++    +  ++LV W   + P  +I GY + Y     P + V    +  V ++ IT 
Sbjct: 421  PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM--DPTQHVNNWMKHNVADSQITT 478

Query: 1872 --GLEPGTEYTIYVIAL----------------KNNQKSEPLIGRKKTGQEALSQTTISW 1913
               L P   Y++ V+A                 +     +PL    K   E+ +   +SW
Sbjct: 479  IGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPL--NFKAEPESETSILLSW 536

Query: 1914 A-PFQDTSEYIISCHPVGTDEEPLQFRV-PGTSTSATLTGLTRGATYNIIVEALKDQQRH 1971
              P  DT       +  G   E  +  + PG  TS  L GL   + Y   + A   Q   
Sbjct: 537  TPPRSDTIANYELVYKDGEHGEEQRITIEPG--TSYRLQGLKPNSLYYFRLAARSPQGLG 594

Query: 1972 KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003
                E ++     ++    P D SC  P + S
Sbjct: 595  ASTAE-ISARTMQSKPSAPPQDISCTSPSSTS 625


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score =  152 bits (383), Expect = 5e-36
 Identities = 263/1257 (20%), Positives = 461/1257 (36%), Gaps = 97/1257 (7%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  SY   GL PG +Y   L  + +    +  R+    T+                  P+
Sbjct: 469  HATSYAFHGLTPGYLYN--LTVMTEAAGLQNYRWKLVRTA------------------PM 508

Query: 722  VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
              ++  VT + + +S  V W      V  + +   LS +G   +   L    T  +  +L
Sbjct: 509  EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKEL 566

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-SIVVRWSRPQAPIT 839
            +PGR Y V V  +S  GE S        T PD   +   +      S+VV WS P     
Sbjct: 567  VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 624

Query: 840  GYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
             YRI+ ++ SV   +  +   ET   +  + L PG QY + +     N +++        
Sbjct: 625  QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERC----- 679

Query: 899  TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
                +  TVP +   L+     +  ++IMW  P +    Y + +   +L   H + L   
Sbjct: 680  ----QGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 734

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
               F   T L PG  Y   V ++S   ++      +T      T+L   N+   S++   
Sbjct: 735  AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 792

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            WT  +  +  Y++ + +      +  ++    S+Y   +L+  S Y+V +  + G   S 
Sbjct: 793  WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
            +      T+    S    N       + ++W  AP       V  S  G+  +   +   
Sbjct: 852  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 911

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                  S LTPG  Y  TI       E  +    + V       ++   A  D   L VS
Sbjct: 912  VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 969

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
            W  +T  D   Y +T    N    N ++ + +   ++ C F  L PG  Y+V+V T    
Sbjct: 970  WVHATG-DFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024

Query: 1254 KESVPISDTIIPAVPPPT-DLRFTNIGPDTMRVTWAPPPS-IDLTNFLVRYSPVKNEEDV 1311
             E+    +     +P P  DL   N   + + VTW+     +D     + ++ +K     
Sbjct: 1025 YEANEQGNG--RTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKV---F 1079

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
                +  +      T+L PG +Y + V ++    + +        G   P+ +    I+ 
Sbjct: 1080 PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI----EGFTVPSAVKNIHISP 1135

Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
            N    S TV+W      +  Y +   RH     S +     +P      T   L  G +Y
Sbjct: 1136 NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 1190

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
             + I +++G  ++ + +  ++  + V   +   A +  SL++SW  A  V  RY  +   
Sbjct: 1191 QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1250

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
            E G    ++  + P +        L PG  Y I +  V+G       SK      RT   
Sbjct: 1251 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGG----LFSKEAQTEGRTVPA 1304

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
              + +++T+     +S +W  S   ++ Y +     +G    + +     Q+      LQ
Sbjct: 1305 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1364

Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTG 1661
              +  +V V     SGE          T+PA         + T  SL   W+P +     
Sbjct: 1365 GRMYKMVIV---THSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDF 1421

Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721
            Y + +      G  KE     D +     GL+   KY + V      L+++      T  
Sbjct: 1422 YELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTA- 1478

Query: 1722 ENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
               SPP      D   T++ I+W+   +      F++  +P +  T              
Sbjct: 1479 --PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI 1536

Query: 1780 ITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 1836
            + GL+PG  Y+  + T++ ++    S P+     T  D   NL        ++  SW PP
Sbjct: 1537 VYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPP 1596

Query: 1837 RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1893
             +   GY I+  K  +   E   +     +   I  L P   Y + +        SE
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSE 1653



 Score =  143 bits (361), Expect = 2e-33
 Identities = 264/1261 (20%), Positives = 478/1261 (37%), Gaps = 129/1261 (10%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
            + +T    N+ DL  G  Y  N   IS D E++++L T     P A    + ++   TS+
Sbjct: 291  IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 346

Query: 828  VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
             V W+     +T Y +            + + E+   N  T  +L  G +YNI I AV  
Sbjct: 347  HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 406

Query: 886  NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
             + S  V     T G+    TVPSP     +      + I W+     V  YR+ ++   
Sbjct: 407  GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 458

Query: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
            +   HG  +     ++A   GL+PG  Y   V   + G ++      +T  ++  +NL+ 
Sbjct: 459  IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 515

Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
             N+   T L V+W  P   +  Y +T  L+ +G  ++  V  P +++   + L P   Y 
Sbjct: 516  TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 573

Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
            V++  + G   + K   V  T     +    N      ++V++W+P      +  +    
Sbjct: 574  VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 632

Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
                    + G E  + V  D+G      L PG +Y   + ++  G  +++        P
Sbjct: 633  DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 685

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            L+        AN  +  L++ W+   TP +  +         +    + + +  D    T
Sbjct: 686  LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 739

Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT-WAPPP 1291
            F +L PG +Y  +V ++  D K S  +    +PA    TDL   N G  +   T W    
Sbjct: 740  FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 797

Query: 1292 S-IDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST 1348
              ++    L+ +  V  KNE      SIS   +     +L  G+ Y V V++V     S 
Sbjct: 798  GDVEFYQVLLIHENVVIKNE------SISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851

Query: 1349 PLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
             +    +T   S +G+  ++   N + +V W+     +  Y +     H     +   + 
Sbjct: 852  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTL--SHDGKVVQSLVIA 909

Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV-AATPTSLLI 1466
             S    + ++LTPG  Y V+I   +G+ E+     Q+ TV D  + + V  +A    L +
Sbjct: 910  KSVRECSFSSLTPGRLYTVTITTRSGKYENHSF-SQERTVPDKVQGVSVSNSARSDYLRV 968

Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
            SW        +Y +T      N+ +Q  ++P S++      L PG  Y++TV   +G+ +
Sbjct: 969  SWVHATGDFDHYEVTIKNK--NNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYE 1026

Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT---TTPKNGPG 1583
            +         N RT  +    + + +     + V W  ++  V  Y +       K  P 
Sbjct: 1027 ANEQG-----NGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP 1081

Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQV 1643
                 TA    TE     L P  +Y + V     SG+ Q        T+P+   +K   +
Sbjct: 1082 FHLVNTA----TEYRFTSLTPGRQYKILVLTI--SGDVQQSAFIEGFTVPSA--VKNIHI 1133

Query: 1644 TPT----SLSAQWTPPNVQLTGYRV-----------RVTPKEKTGPMKEINLAPDSSSVV 1688
            +P     SL+  WTP    +  Y V           +  PK           A +   ++
Sbjct: 1134 SPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIM 1193

Query: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748
            ++ +  + K +++V            QGV+                 +  ++ +SW+   
Sbjct: 1194 IASVSGSLKNQINVVG---RTVPASVQGVIAD------------NAYSSYSLIVSWQKAA 1238

Query: 1749 ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
                 + +  +  NG   ++ T +P   + +    L PG  YKI + T++    S     
Sbjct: 1239 GVAERYDILLLTENGIL-LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQT 1297

Query: 1808 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
            +  T   A ++LR    +   L   W      ++ Y I    P    +E   +  P V  
Sbjct: 1298 EGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERA-QVDPLVQS 1356

Query: 1868 ATITGLEPGTEYTIYVIALKNNQKSEPLI-GR---------KKTGQEALSQTTISWAPFQ 1917
             +   L  G  Y + ++       +E  I GR         + + +        +W+P  
Sbjct: 1357 FSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPAS 1416

Query: 1918 DTSEY--IISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVRE 1975
               ++  +I  +P GT +E  + +     T     GL  G  Y + V        +KV  
Sbjct: 1417 GDFDFYELILYNPNGTKKENWKDK---DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTA 1473

Query: 1976 E 1976
            E
Sbjct: 1474 E 1474



 Score =  131 bits (330), Expect = 6e-30
 Identities = 240/1156 (20%), Positives = 452/1156 (39%), Gaps = 103/1156 (8%)

Query: 798  EQSLILSTSQ----TTAPDAPPDP-------TVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
            + S +LST+Q    TT      +P          +    S+ ++W    +P   + ++YS
Sbjct: 219  DTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRILGSPCN-FSLIYS 277

Query: 847  PSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
                G++      +  T     L DLQ G  YN  I +++E +    VV+Q        +
Sbjct: 278  SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERT---VVLQ--------T 326

Query: 905  DTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
            D +P  R  +   + T   + + WTP    VT Y V +   N     G ++  S  ++ E
Sbjct: 327  DPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQES-TSWNE 385

Query: 964  VT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             T   L+ G  Y   + AVS G+ S  +    +T + +P     ++   +++L+ W+   
Sbjct: 386  YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSPVKDIGISTKANSLLISWSHGS 444

Query: 1022 AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
              +  YRL +   G+   G      V    + Y    L P   Y ++++      ++ + 
Sbjct: 445  GNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRW 500

Query: 1079 TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGG--EAPREVTSDSG 1136
              V T     S++   N + + T++ + W   P       +  S  G  +  R +     
Sbjct: 501  KLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVS 1194
                  L PG  Y  T+  +          V +      P    +LEAN +  +  L VS
Sbjct: 560  ETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF----PDKVANLEANNNGRMRSLVVS 615

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVYTVKD 1252
            W      D   YRI            L   V  +++    D+  L PG +Y V V     
Sbjct: 616  WS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESG 671

Query: 1253 D-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV 1311
            + K S       +P       LR  +    ++ + W  P + +   +++  S    +  +
Sbjct: 672  NLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTPVA-EWEKYII--SLADRDLLL 726

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
               S+S        T+L+PG +Y+ +V+S+  +   S+ ++GR      +   +    +T
Sbjct: 727  IHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT 786

Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            ++ FT +W   +  +  Y++    E+     + + +    +  +  +L  G+ Y V +  
Sbjct: 787  SSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSETSRYSFHSLKSGSLYSVVVTT 843

Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LLISWDAPAVTVRYYRITYGETG 1486
            ++G   S  ++ +  T   VP  +  V    +     L +SW      V  Y +T    G
Sbjct: 844  VSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG 900

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                VQ   +  S    + S L PG  YT+T+   +G+ ++ + S+      RT  DK  
Sbjct: 901  --KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQE-----RTVPDKVQ 953

Query: 1547 QMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             + V++  + + + V W+ ++     Y VT   KN     +TK+    + E     L P 
Sbjct: 954  GVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NFIQTKSIPKSENECVFVQLVPG 1011

Query: 1606 VEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRV 1664
              Y V+V  +  SG+ +   Q    TIP P  DL     +   L   W+  N  +  Y +
Sbjct: 1012 RLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEI 1069

Query: 1665 RVTPKE-KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK-DTLTSRPAQG--VVTT 1720
            ++   + K  P    +L   ++    + L    +Y++ V  +  D   S   +G  V + 
Sbjct: 1070 QLLFNDMKVFP--PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSA 1127

Query: 1721 LEN--VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
            ++N  +SP       +    ++T++W      +  + V A   + Q    +TI   V  +
Sbjct: 1128 VKNIHISP-------NGATDSLTVNWTPGGGDVDSYTVSAF-RHSQKVDSQTIPKHVFEH 1179

Query: 1779 TITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRA 1838
            T   L+ G  Y+I + +++ + ++   V+  +        +   A +  SL+VSWQ    
Sbjct: 1180 TFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAG 1239

Query: 1839 RITGY-IIKYEKPGSPPREVVPRPRPGVT-EATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
                Y I+   + G   R       P  T +     L PG +Y I ++ +     S+   
Sbjct: 1240 VAERYDILLLTENGILLRNT---SEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQ 1296

Query: 1897 GRKKTGQEALSQTTIS 1912
               +T   A++   I+
Sbjct: 1297 TEGRTVPAAVTDLRIT 1312



 Score =  119 bits (299), Expect = 2e-26
 Identities = 262/1207 (21%), Positives = 441/1207 (36%), Gaps = 122/1207 (10%)

Query: 660  PGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP-- 717
            PG+++SY I     G + E ++++         T F          VT + V+GE +   
Sbjct: 532  PGNVDSYNITLSHKGTIKESRVLA----PWITETHFKELVPGRLYQVTVSCVSGELSAQK 587

Query: 718  ------FSPLVATSESVTEITASSFVVSWVSASDTVSGFR--------VEYELSEEGDEP 763
                  F   VA  E+       S VVSW   +     +R        V   ++   +E 
Sbjct: 588  MAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEET 647

Query: 764  QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVD 823
            QY+        ++   L+PGR+Y V V  I E G           T P A     V   +
Sbjct: 648  QYV--------MDDTGLVPGRQYEVEV--IVESGNLKNSERCQGRTVPLAVLQLRVKHAN 697

Query: 824  DTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
            +TS+ + W  P A    Y I+     +      +L + A   T +DL PG +Y  T+ ++
Sbjct: 698  ETSLSIMWQTPVAEWEKY-IISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSI 756

Query: 884  EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM---------WTPPESAV 934
              + +++  V         +  TVP+       +VTD+ V            WT  +  V
Sbjct: 757  SGDLKNSSSV---------KGRTVPA-------QVTDLHVANQGMTSSLFTNWTQAQGDV 800

Query: 935  TGYRVDVIPVNLPGEHGQ-RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
              Y+V +I  N+  ++       SR +F     L  G  Y   V  VS G  S+ +  + 
Sbjct: 801  EFYQVLLIHENVVIKNESISSETSRYSFHS---LKSGSLYSVVVTTVSGGISSRQVVVEG 857

Query: 994  TTKLDAPTNLQFVNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKY 1051
             T   + + +   N   +  L V W      +  Y +T  L+  G+  Q  V   SV + 
Sbjct: 858  RTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVT--LSHDGKVVQSLVIAKSVREC 915

Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
               +L P   YTV++    G  E+   +   T       +   N+  ++  + ++W  A 
Sbjct: 916  SFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDY-LRVSWVHAT 974

Query: 1112 RI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
                 +++ ++        + +       V   L PG  Y  T+   + GQ       N 
Sbjct: 975  GDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT-KSGQYEANEQGNG 1033

Query: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
               P  P  +L L  N  T  L V+W      D+  Y I     + +       V  A +
Sbjct: 1034 RTIP-EPVKDLTLR-NRSTEDLHVTWS-GANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 1090

Query: 1230 SSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGP----DTMRV 1285
                F +L+PG +Y + V T+  D +        I     P+ ++  +I P    D++ V
Sbjct: 1091 YR--FTSLTPGRQYKILVLTISGDVQQ----SAFIEGFTVPSAVKNIHISPNGATDSLTV 1144

Query: 1286 TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQH 1345
             W P    D+ ++ V  S  ++ + V   +I           L  G +Y + ++SV    
Sbjct: 1145 NWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASV---- 1197

Query: 1346 ESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIRHHPEHFSGR 1400
             S  L+ +    G   P  +    +D   +S++  V W         Y I    E+    
Sbjct: 1198 -SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTEN-GIL 1255

Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
             R    P +       +LTPG +Y + I+ ++G   S     +  TV     DL +   +
Sbjct: 1256 LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENS 1315

Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
               L   W A    + +Y I      GN   +    P  +S  +   L  G  Y + +  
Sbjct: 1316 TRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQGRMYKMVIVT 1374

Query: 1521 VTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1576
             +G   + +     + P S+++     + S    TD    S+   W P+S     Y +  
Sbjct: 1375 HSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASGDFDFYELIL 1426

Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT 1636
               N  G  K      D TE   +GL P  +YV+ V     SG+    V     T P+P 
Sbjct: 1427 YNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTAESRTAPSPP 1482

Query: 1637 DL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1693
             L  F  +  TSL+  W  PP+      + ++  P++        N    S   +V GL 
Sbjct: 1483 SLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIVYGLR 1541

Query: 1694 VATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1750
                Y+ +V  +        S+P  G V T  +       R  ++  T I  SW      
Sbjct: 1542 PGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIPPDSD 1599

Query: 1751 ITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1809
              G+ ++    + Q     R ++ +     I  L P   Y + +   +    S  V    
Sbjct: 1600 FDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDST 1659

Query: 1810 STAIDAP 1816
             T ID P
Sbjct: 1660 ITMIDRP 1666



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 189/910 (20%), Positives = 335/910 (36%), Gaps = 94/910 (10%)

Query: 1150 VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT 1209
            +Y  +++   +ER   +      PL PP    +     T      W   ++  +T Y + 
Sbjct: 308  IYNFRIISLDEERTVVLQTD---PL-PPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQ 363

Query: 1210 TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP 1269
                N Q+   ++       +  TF NL+ G +YN+++  V   K S  +  T    VP 
Sbjct: 364  LFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVY-TNGSTVPS 422

Query: 1270 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS--ISPSDNAVVLTN 1327
            P      +   +++ ++W+       +  + RY  +  ++ +      +     +     
Sbjct: 423  PVKDIGISTKANSLLISWSHG-----SGNVERYRLMLMDKGILVHGGVVDKHATSYAFHG 477

Query: 1328 LLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTGID----FSDITANSFTVHWIAPR 1382
            L PG  Y ++V +     E+  L+  R K    +P  +      +D +  S  V W  P 
Sbjct: 478  LTPGYLYNLTVMT-----EAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPP 532

Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT-LTNLTPGTEYVVSIVALNGREESPLLI 1441
              +  Y I        G  +E RV     + T    L PG  Y V++  ++G E S   +
Sbjct: 533  GNVDSYNI---TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSG-ELSAQKM 588

Query: 1442 GQQSTVSDVPRDLEV-VAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
                T  D   +LE        SL++SW  PA     YRI       +S V      G +
Sbjct: 589  AVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRIL---LFNDSVVLLNITVGKE 645

Query: 1501 STATI---SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNS 1557
             T  +   +GL PG  Y + V   +G   +    +      RT      Q++V    + S
Sbjct: 646  ETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQG-----RTVPLAVLQLRVKHANETS 700

Query: 1558 ISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1617
            +S+ W    +    Y ++   ++       K+   D  E T   L P  +Y+ +V   + 
Sbjct: 701  LSIMWQTPVAEWEKYIISLADRD--LLLIHKSLSKDAKEFTFTDLVPGRKYMATV--TSI 756

Query: 1618 SGESQPLVQTAVTTIPAP-TDLKF-TQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
            SG+ +        T+PA  TDL    Q   +SL   WT     +  Y+V +  +     +
Sbjct: 757  SGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVV--I 814

Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR----PAQGVVTTLENVSPPRRAR 1731
            K  +++ ++S      L   + Y V V  +   ++SR      + V +++  V+     R
Sbjct: 815  KNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGR 874

Query: 1732 VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
                    +++SW      +  ++V  +  +G+      I   VR  + + L PG  Y +
Sbjct: 875  -----NDYLSVSWLLAPGDVDNYEV-TLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTV 928

Query: 1792 YLYTL-----NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIK 1846
             + T      N +      V D    +   ++ R      + L VSW       TG    
Sbjct: 929  TITTRSGKYENHSFSQERTVPDKVQGVSVSNSAR-----SDYLRVSW----VHATGDFDH 979

Query: 1847 YE-----KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1901
            YE     K      + +P+      E     L PG  Y++  +  K+ Q      G  +T
Sbjct: 980  YEVTIKNKNNFIQTKSIPKSE---NECVFVQLVPGRLYSV-TVTTKSGQYEANEQGNGRT 1035

Query: 1902 GQEALSQTT----------ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 1950
              E +   T          ++W+    D  +Y I          P  F +  T+T    T
Sbjct: 1036 IPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP-PFHLVNTATEYRFT 1094

Query: 1951 GLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE 2010
             LT G  Y I+V  +    +     E  TV ++V      P  +   D  TV+    G +
Sbjct: 1095 SLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISP--NGATDSLTVNWTPGGGD 1152

Query: 2011 WERMSESGFK 2020
             +  + S F+
Sbjct: 1153 VDSYTVSAFR 1162



 Score = 35.4 bits (80), Expect = 0.62
 Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)

Query: 628  IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
            I W  P   +  + + L+W P++++     +      G +    + GL+PG  Y+  + +
Sbjct: 1497 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1552

Query: 684  IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
            +     +  ++  F +  T      N           L    ++ T I  S     W+  
Sbjct: 1553 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1596

Query: 744  SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
                 G+ +E    +  +      L    + +NI  L+P ++Y+V++ ++   G  S ++
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1655

Query: 804  STSQTTAPDAPPDP 817
              S  T  D PP P
Sbjct: 1656 EDSTITMIDRPPPP 1669


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score =  152 bits (383), Expect = 5e-36
 Identities = 263/1257 (20%), Positives = 461/1257 (36%), Gaps = 97/1257 (7%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  SY   GL PG +Y   L  + +    +  R+    T+                  P+
Sbjct: 251  HATSYAFHGLTPGYLYN--LTVMTEAAGLQNYRWKLVRTA------------------PM 290

Query: 722  VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
              ++  VT + + +S  V W      V  + +   LS +G   +   L    T  +  +L
Sbjct: 291  EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKEL 348

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-SIVVRWSRPQAPIT 839
            +PGR Y V V  +S  GE S        T PD   +   +      S+VV WS P     
Sbjct: 349  VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 406

Query: 840  GYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
             YRI+ ++ SV   +  +   ET   +  + L PG QY + +     N +++        
Sbjct: 407  QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERC----- 461

Query: 899  TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
                +  TVP +   L+     +  ++IMW  P +    Y + +   +L   H + L   
Sbjct: 462  ----QGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 516

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
               F   T L PG  Y   V ++S   ++      +T      T+L   N+   S++   
Sbjct: 517  AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 574

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            WT  +  +  Y++ + +      +  ++    S+Y   +L+  S Y+V +  + G   S 
Sbjct: 575  WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
            +      T+    S    N       + ++W  AP       V  S  G+  +   +   
Sbjct: 634  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 693

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                  S LTPG  Y  TI       E  +    + V       ++   A  D   L VS
Sbjct: 694  VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 751

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
            W  +T  D   Y +T    N    N ++ + +   ++ C F  L PG  Y+V+V T    
Sbjct: 752  WVHATG-DFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 806

Query: 1254 KESVPISDTIIPAVPPPT-DLRFTNIGPDTMRVTWAPPPS-IDLTNFLVRYSPVKNEEDV 1311
             E+    +     +P P  DL   N   + + VTW+     +D     + ++ +K     
Sbjct: 807  YEANEQGNG--RTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKV---F 861

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
                +  +      T+L PG +Y + V ++    + +        G   P+ +    I+ 
Sbjct: 862  PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI----EGFTVPSAVKNIHISP 917

Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
            N    S TV+W      +  Y +   RH     S +     +P      T   L  G +Y
Sbjct: 918  NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 972

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
             + I +++G  ++ + +  ++  + V   +   A +  SL++SW  A  V  RY  +   
Sbjct: 973  QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1032

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
            E G    ++  + P +        L PG  Y I +  V+G       SK      RT   
Sbjct: 1033 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGG----LFSKEAQTEGRTVPA 1086

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
              + +++T+     +S +W  S   ++ Y +     +G    + +     Q+      LQ
Sbjct: 1087 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1146

Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWTPPNVQLTG 1661
              +  +V V     SGE          T+PA         + T  SL   W+P +     
Sbjct: 1147 GRMYKMVIV---THSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDF 1203

Query: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721
            Y + +      G  KE     D +     GL+   KY + V      L+++      T  
Sbjct: 1204 YELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTA- 1260

Query: 1722 ENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
               SPP      D   T++ I+W+   +      F++  +P +  T              
Sbjct: 1261 --PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI 1318

Query: 1780 ITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 1836
            + GL+PG  Y+  + T++ ++    S P+     T  D   NL        ++  SW PP
Sbjct: 1319 VYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPP 1378

Query: 1837 RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1893
             +   GY I+  K  +   E   +     +   I  L P   Y + +        SE
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSE 1435



 Score =  143 bits (361), Expect = 2e-33
 Identities = 264/1261 (20%), Positives = 478/1261 (37%), Gaps = 129/1261 (10%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
            + +T    N+ DL  G  Y  N   IS D E++++L T     P A    + ++   TS+
Sbjct: 73   IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 128

Query: 828  VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
             V W+     +T Y +            + + E+   N  T  +L  G +YNI I AV  
Sbjct: 129  HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 188

Query: 886  NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
             + S  V     T G+    TVPSP     +      + I W+     V  YR+ ++   
Sbjct: 189  GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 240

Query: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
            +   HG  +     ++A   GL+PG  Y   V   + G ++      +T  ++  +NL+ 
Sbjct: 241  IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 297

Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
             N+   T L V+W  P   +  Y +T  L+ +G  ++  V  P +++   + L P   Y 
Sbjct: 298  TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 355

Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
            V++  + G   + K   V  T     +    N      ++V++W+P      +  +    
Sbjct: 356  VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 414

Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
                    + G E  + V  D+G      L PG +Y   + ++  G  +++        P
Sbjct: 415  DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 467

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            L+        AN  +  L++ W+   TP +  +         +    + + +  D    T
Sbjct: 468  LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 521

Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT-WAPPP 1291
            F +L PG +Y  +V ++  D K S  +    +PA    TDL   N G  +   T W    
Sbjct: 522  FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 579

Query: 1292 S-IDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST 1348
              ++    L+ +  V  KNE      SIS   +     +L  G+ Y V V++V     S 
Sbjct: 580  GDVEFYQVLLIHENVVIKNE------SISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633

Query: 1349 PLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
             +    +T   S +G+  ++   N + +V W+     +  Y +     H     +   + 
Sbjct: 634  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTL--SHDGKVVQSLVIA 691

Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV-AATPTSLLI 1466
             S    + ++LTPG  Y V+I   +G+ E+     Q+ TV D  + + V  +A    L +
Sbjct: 692  KSVRECSFSSLTPGRLYTVTITTRSGKYENHSF-SQERTVPDKVQGVSVSNSARSDYLRV 750

Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
            SW        +Y +T      N+ +Q  ++P S++      L PG  Y++TV   +G+ +
Sbjct: 751  SWVHATGDFDHYEVTIKNK--NNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYE 808

Query: 1527 SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT---TTPKNGPG 1583
            +         N RT  +    + + +     + V W  ++  V  Y +       K  P 
Sbjct: 809  ANEQG-----NGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP 863

Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQV 1643
                 TA    TE     L P  +Y + V     SG+ Q        T+P+   +K   +
Sbjct: 864  FHLVNTA----TEYRFTSLTPGRQYKILVLTI--SGDVQQSAFIEGFTVPSA--VKNIHI 915

Query: 1644 TPT----SLSAQWTPPNVQLTGYRV-----------RVTPKEKTGPMKEINLAPDSSSVV 1688
            +P     SL+  WTP    +  Y V           +  PK           A +   ++
Sbjct: 916  SPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIM 975

Query: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748
            ++ +  + K +++V            QGV+                 +  ++ +SW+   
Sbjct: 976  IASVSGSLKNQINVVG---RTVPASVQGVIAD------------NAYSSYSLIVSWQKAA 1020

Query: 1749 ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
                 + +  +  NG   ++ T +P   + +    L PG  YKI + T++    S     
Sbjct: 1021 GVAERYDILLLTENGIL-LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQT 1079

Query: 1808 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
            +  T   A ++LR    +   L   W      ++ Y I    P    +E   +  P V  
Sbjct: 1080 EGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERA-QVDPLVQS 1138

Query: 1868 ATITGLEPGTEYTIYVIALKNNQKSEPLI-GR---------KKTGQEALSQTTISWAPFQ 1917
             +   L  G  Y + ++       +E  I GR         + + +        +W+P  
Sbjct: 1139 FSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPAS 1198

Query: 1918 DTSEY--IISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVRE 1975
               ++  +I  +P GT +E  + +     T     GL  G  Y + V        +KV  
Sbjct: 1199 GDFDFYELILYNPNGTKKENWKDK---DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTA 1255

Query: 1976 E 1976
            E
Sbjct: 1256 E 1256



 Score =  131 bits (329), Expect = 8e-30
 Identities = 232/1117 (20%), Positives = 439/1117 (39%), Gaps = 92/1117 (8%)

Query: 826  SIVVRWSRPQAPITGYRIVYSPSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAV 883
            S+ ++W    +P   + ++YS    G++      +  T     L DLQ G  YN  I ++
Sbjct: 40   SVSIQWRILGSPCN-FSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISL 98

Query: 884  EENQESTPVVIQQETTGTPRSDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
            +E +    VV+Q        +D +P  R  +   + T   + + WTP    VT Y V + 
Sbjct: 99   DEERT---VVLQ--------TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLF 147

Query: 943  PVNLPGEHGQRLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
              N     G ++  S  ++ E T   L+ G  Y   + AVS G+ S  +    +T + +P
Sbjct: 148  DENNQKIQGVQIQES-TSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSP 205

Query: 1001 TNLQFVNETDSTVLVRWTPPRAQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQ 1057
                 ++   +++L+ W+     +  YRL +   G+   G      V    + Y    L 
Sbjct: 206  VKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLT 261

Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
            P   Y ++++      ++ +   V T     S++   N + + T++ + W   P      
Sbjct: 262  PGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSY 320

Query: 1118 GVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
             +  S  G  +  R +           L PG  Y  T+  +          V +      
Sbjct: 321  NITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF---- 376

Query: 1176 PPTNLHLEANPDTGV--LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            P    +LEAN +  +  L VSW      D   YRI            L   V  +++   
Sbjct: 377  PDKVANLEANNNGRMRSLVVSWS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYV 432

Query: 1234 FDN--LSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
             D+  L PG +Y V V     + K S       +P       LR  +    ++ + W  P
Sbjct: 433  MDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTP 490

Query: 1291 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTP 1349
             + +   +++  S    +  +   S+S        T+L+PG +Y+ +V+S+  +   S+ 
Sbjct: 491  VA-EWEKYII--SLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSS 547

Query: 1350 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1409
            ++GR      +   +    +T++ FT +W   +  +  Y++    E+     + + +   
Sbjct: 548  VKGRTVPAQVTDLHVANQGMTSSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSE 604

Query: 1410 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LL 1465
             +  +  +L  G+ Y V +  ++G   S  ++ +  T   VP  +  V    +     L 
Sbjct: 605  TSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLS 661

Query: 1466 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
            +SW      V  Y +T    G    VQ   +  S    + S L PG  YT+T+   +G+ 
Sbjct: 662  VSWLLAPGDVDNYEVTLSHDG--KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKY 719

Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584
            ++ + S+      RT  DK   + V++  + + + V W+ ++     Y VT   KN    
Sbjct: 720  ENHSFSQE-----RTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NF 772

Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
             +TK+    + E     L P   Y V+V  +  SG+ +   Q    TIP P  DL     
Sbjct: 773  IQTKSIPKSENECVFVQLVPGRLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNR 830

Query: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKE-KTGPMKEINLAPDSSSVVVSGLMVATKYEVSV 1702
            +   L   W+  N  +  Y +++   + K  P    +L   ++    + L    +Y++ V
Sbjct: 831  STEDLHVTWSGANGDVDQYEIQLLFNDMKVFP--PFHLVNTATEYRFTSLTPGRQYKILV 888

Query: 1703 YALK-DTLTSRPAQG--VVTTLEN--VSPPRRARVTDATETTITISWRTKTETITGFQVD 1757
              +  D   S   +G  V + ++N  +SP       +    ++T++W      +  + V 
Sbjct: 889  LTISGDVQQSAFIEGFTVPSAVKNIHISP-------NGATDSLTVNWTPGGGDVDSYTVS 941

Query: 1758 AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS 1817
            A   + Q    +TI   V  +T   L+ G  Y+I + +++ + ++   V+  +       
Sbjct: 942  AF-RHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQG 1000

Query: 1818 NLRFLATTPNSLLVSWQPPRARITGY-IIKYEKPGSPPREVVPRPRPGVT-EATITGLEP 1875
             +   A +  SL+VSWQ        Y I+   + G   R       P  T +     L P
Sbjct: 1001 VIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNT---SEPATTKQHKFEDLTP 1057

Query: 1876 GTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTIS 1912
            G +Y I ++ +     S+      +T   A++   I+
Sbjct: 1058 GKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRIT 1094



 Score =  119 bits (299), Expect = 2e-26
 Identities = 262/1207 (21%), Positives = 441/1207 (36%), Gaps = 122/1207 (10%)

Query: 660  PGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP-- 717
            PG+++SY I     G + E ++++         T F          VT + V+GE +   
Sbjct: 314  PGNVDSYNITLSHKGTIKESRVLA----PWITETHFKELVPGRLYQVTVSCVSGELSAQK 369

Query: 718  ------FSPLVATSESVTEITASSFVVSWVSASDTVSGFR--------VEYELSEEGDEP 763
                  F   VA  E+       S VVSW   +     +R        V   ++   +E 
Sbjct: 370  MAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEET 429

Query: 764  QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVD 823
            QY+        ++   L+PGR+Y V V  I E G           T P A     V   +
Sbjct: 430  QYV--------MDDTGLVPGRQYEVEV--IVESGNLKNSERCQGRTVPLAVLQLRVKHAN 479

Query: 824  DTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
            +TS+ + W  P A    Y I+     +      +L + A   T +DL PG +Y  T+ ++
Sbjct: 480  ETSLSIMWQTPVAEWEKY-IISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSI 538

Query: 884  EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM---------WTPPESAV 934
              + +++  V         +  TVP+       +VTD+ V            WT  +  V
Sbjct: 539  SGDLKNSSSV---------KGRTVPA-------QVTDLHVANQGMTSSLFTNWTQAQGDV 582

Query: 935  TGYRVDVIPVNLPGEHGQ-RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
              Y+V +I  N+  ++       SR +F     L  G  Y   V  VS G  S+ +  + 
Sbjct: 583  EFYQVLLIHENVVIKNESISSETSRYSFHS---LKSGSLYSVVVTTVSGGISSRQVVVEG 639

Query: 994  TTKLDAPTNLQFVNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKY 1051
             T   + + +   N   +  L V W      +  Y +T  L+  G+  Q  V   SV + 
Sbjct: 640  RTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVT--LSHDGKVVQSLVIAKSVREC 697

Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
               +L P   YTV++    G  E+   +   T       +   N+  ++  + ++W  A 
Sbjct: 698  SFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDY-LRVSWVHAT 756

Query: 1112 RI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
                 +++ ++        + +       V   L PG  Y  T+   + GQ       N 
Sbjct: 757  GDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT-KSGQYEANEQGNG 815

Query: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
               P  P  +L L  N  T  L V+W      D+  Y I     + +       V  A +
Sbjct: 816  RTIP-EPVKDLTLR-NRSTEDLHVTWS-GANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 872

Query: 1230 SSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGP----DTMRV 1285
                F +L+PG +Y + V T+  D +        I     P+ ++  +I P    D++ V
Sbjct: 873  YR--FTSLTPGRQYKILVLTISGDVQQ----SAFIEGFTVPSAVKNIHISPNGATDSLTV 926

Query: 1286 TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQH 1345
             W P    D+ ++ V  S  ++ + V   +I           L  G +Y + ++SV    
Sbjct: 927  NWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASV---- 979

Query: 1346 ESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIRHHPEHFSGR 1400
             S  L+ +    G   P  +    +D   +S++  V W         Y I    E+    
Sbjct: 980  -SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTEN-GIL 1037

Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
             R    P +       +LTPG +Y + I+ ++G   S     +  TV     DL +   +
Sbjct: 1038 LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENS 1097

Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
               L   W A    + +Y I      GN   +    P  +S  +   L  G  Y + +  
Sbjct: 1098 TRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQGRMYKMVIVT 1156

Query: 1521 VTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1576
             +G   + +     + P S+++     + S    TD    S+   W P+S     Y +  
Sbjct: 1157 HSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASGDFDFYELIL 1208

Query: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT 1636
               N  G  K      D TE   +GL P  +YV+ V     SG+    V     T P+P 
Sbjct: 1209 YNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTAESRTAPSPP 1264

Query: 1637 DL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1693
             L  F  +  TSL+  W  PP+      + ++  P++        N    S   +V GL 
Sbjct: 1265 SLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIVYGLR 1323

Query: 1694 VATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1750
                Y+ +V  +        S+P  G V T  +       R  ++  T I  SW      
Sbjct: 1324 PGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIPPDSD 1381

Query: 1751 ITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1809
              G+ ++    + Q     R ++ +     I  L P   Y + +   +    S  V    
Sbjct: 1382 FDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDST 1441

Query: 1810 STAIDAP 1816
             T ID P
Sbjct: 1442 ITMIDRP 1448



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 189/910 (20%), Positives = 335/910 (36%), Gaps = 94/910 (10%)

Query: 1150 VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT 1209
            +Y  +++   +ER   +      PL PP    +     T      W   ++  +T Y + 
Sbjct: 90   IYNFRIISLDEERTVVLQTD---PL-PPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQ 145

Query: 1210 TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP 1269
                N Q+   ++       +  TF NL+ G +YN+++  V   K S  +  T    VP 
Sbjct: 146  LFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVY-TNGSTVPS 204

Query: 1270 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS--ISPSDNAVVLTN 1327
            P      +   +++ ++W+       +  + RY  +  ++ +      +     +     
Sbjct: 205  PVKDIGISTKANSLLISWSHG-----SGNVERYRLMLMDKGILVHGGVVDKHATSYAFHG 259

Query: 1328 LLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTGID----FSDITANSFTVHWIAPR 1382
            L PG  Y ++V +     E+  L+  R K    +P  +      +D +  S  V W  P 
Sbjct: 260  LTPGYLYNLTVMT-----EAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPP 314

Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT-LTNLTPGTEYVVSIVALNGREESPLLI 1441
              +  Y I        G  +E RV     + T    L PG  Y V++  ++G E S   +
Sbjct: 315  GNVDSYNI---TLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSG-ELSAQKM 370

Query: 1442 GQQSTVSDVPRDLEV-VAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
                T  D   +LE        SL++SW  PA     YRI       +S V      G +
Sbjct: 371  AVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRIL---LFNDSVVLLNITVGKE 427

Query: 1501 STATI---SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNS 1557
             T  +   +GL PG  Y + V   +G   +    +      RT      Q++V    + S
Sbjct: 428  ETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQG-----RTVPLAVLQLRVKHANETS 482

Query: 1558 ISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1617
            +S+ W    +    Y ++   ++       K+   D  E T   L P  +Y+ +V   + 
Sbjct: 483  LSIMWQTPVAEWEKYIISLADRD--LLLIHKSLSKDAKEFTFTDLVPGRKYMATV--TSI 538

Query: 1618 SGESQPLVQTAVTTIPAP-TDLKF-TQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
            SG+ +        T+PA  TDL    Q   +SL   WT     +  Y+V +  +     +
Sbjct: 539  SGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVV--I 596

Query: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR----PAQGVVTTLENVSPPRRAR 1731
            K  +++ ++S      L   + Y V V  +   ++SR      + V +++  V+     R
Sbjct: 597  KNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGR 656

Query: 1732 VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
                    +++SW      +  ++V  +  +G+      I   VR  + + L PG  Y +
Sbjct: 657  -----NDYLSVSWLLAPGDVDNYEV-TLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTV 710

Query: 1792 YLYTL-----NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIK 1846
             + T      N +      V D    +   ++ R      + L VSW       TG    
Sbjct: 711  TITTRSGKYENHSFSQERTVPDKVQGVSVSNSAR-----SDYLRVSW----VHATGDFDH 761

Query: 1847 YE-----KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1901
            YE     K      + +P+      E     L PG  Y++  +  K+ Q      G  +T
Sbjct: 762  YEVTIKNKNNFIQTKSIPKSE---NECVFVQLVPGRLYSV-TVTTKSGQYEANEQGNGRT 817

Query: 1902 GQEALSQTT----------ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 1950
              E +   T          ++W+    D  +Y I          P  F +  T+T    T
Sbjct: 818  IPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFP-PFHLVNTATEYRFT 876

Query: 1951 GLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE 2010
             LT G  Y I+V  +    +     E  TV ++V      P  +   D  TV+    G +
Sbjct: 877  SLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISP--NGATDSLTVNWTPGGGD 934

Query: 2011 WERMSESGFK 2020
             +  + S F+
Sbjct: 935  VDSYTVSAFR 944



 Score = 35.4 bits (80), Expect = 0.62
 Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)

Query: 628  IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
            I W  P   +  + + L+W P++++     +      G +    + GL+PG  Y+  + +
Sbjct: 1279 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1334

Query: 684  IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
            +     +  ++  F +  T      N           L    ++ T I  S     W+  
Sbjct: 1335 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1378

Query: 744  SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
                 G+ +E    +  +      L    + +NI  L+P ++Y+V++ ++   G  S ++
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1437

Query: 804  STSQTTAPDAPPDP 817
              S  T  D PP P
Sbjct: 1438 EDSTITMIDRPPPP 1451


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
            isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score =  150 bits (379), Expect = 1e-35
 Identities = 163/667 (24%), Positives = 267/667 (40%), Gaps = 79/667 (11%)

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1429
            TA S T+ W +       Y +  +       P + +   +    ++  L+P +EY + + 
Sbjct: 331  TATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVS 390

Query: 1430 ALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRYYRI 1480
            A+N   + P         G+Q+  S  PR+++    + T++++ W+ P      +R YR+
Sbjct: 391  AVNSIGQGPPSESVVTRTGEQAPAS-APRNVQARMLSATTMIVQWEEPVEPNGLIRGYRV 449

Query: 1481 TYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
             Y       PV   Q+  V  S  T T+  L     YT+ V A T  GD P S  PI + 
Sbjct: 450  YY-TMEPEHPVGNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSD-PIQVK 506

Query: 1538 YRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
             +  +  +P  ++     + SI++ W P              +   G    +T  P  T 
Sbjct: 507  TQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPT-TS 565

Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQ--PLV-QTAVTTIPA--PTDLKFTQVTPTSLSAQ 1651
              +E L+P  EY   + A++P G     P+V Q  + + P+  P D+K   V  T++   
Sbjct: 566  YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVS 625

Query: 1652 WTPP-----NVQLTGYRVRVTPKEKTGPM-KEIN-LAPDSSSVVVSGLMVATKYEVSVYA 1704
            W PP     N  L GY VR  P     P  KE+N + P ++ +++  L   T+Y ++  A
Sbjct: 626  WRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVA 685

Query: 1705 LKDTLTSRPAQGVVT-TLENV--SPPRRARVTDATETTITISWRTKTE-----TITGFQV 1756
              +      +  VV  T E+V  +PPR+        T I + WR+         I G+QV
Sbjct: 686  HTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQV 745

Query: 1757 -----DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL--YTLN-DNARSSPVVID 1808
                 +   A G   I+  +  D +   IT LQP T Y I +  YT+  D ARS P V+ 
Sbjct: 746  HYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVV 805

Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
               A+     L    T   SLL  W+PP      ++ GY +++ +  S P   +  P P 
Sbjct: 806  TKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFP-PS 864

Query: 1865 VTEATITGLEPGTEYTIYVIAL----------------KNNQKSEPLIGRKKTGQEALSQ 1908
                T +G+  G  Y   + A                 ++  +  P I  +  G  +   
Sbjct: 865  EDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQI-LEAAGNASAGT 923

Query: 1909 TTISWAPFQDTS------EYIISCHPVGT-----DEEPLQFRVPGTSTSATLTGLTRGAT 1957
              + W P           +Y ++    G      + E      PG   + TL GL     
Sbjct: 924  VLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTA 983

Query: 1958 YNIIVEA 1964
            Y++ V A
Sbjct: 984  YDLQVRA 990



 Score =  120 bits (301), Expect = 1e-26
 Identities = 192/881 (21%), Positives = 339/881 (38%), Gaps = 110/881 (12%)

Query: 752  VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
            ++ E SEE D+ +Y  + + +  V      P   Y+    ++     +  IL  S    P
Sbjct: 192  LQIESSEETDQGKYECVATNSAGVRYSS--PANLYV----RVRRVAPRFSILPMSHEIMP 245

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
                + T   V      V+W +                E  + E ++P   N + L+D++
Sbjct: 246  GGNVNITCVAVGSPMPYVKWMQ--------------GAEDLTPEDDMPVGRNVLELTDVK 291

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
                Y     +     E+   V Q      P++   P        E T   +TI W    
Sbjct: 292  DSANYTCVAMSSLGVIEA---VAQITVKSLPKAPGTP-----MVTENTATSITITWDSGN 343

Query: 932  -SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
               V+ Y ++    +  G +  +  I+   ++ + GLSP   Y   V AV+   +  P  
Sbjct: 344  PDPVSYYVIEYKSKSQDGPYQIKEDITTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSE 402

Query: 991  AQQT-----TKLDAPTNLQFVNETDSTVLVRW---TPPRAQITGYRLTVGLTRR---GQP 1039
            +  T         AP N+Q    + +T++V+W     P   I GYR+   +      G  
Sbjct: 403  SVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNW 462

Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
            +++NV  S+    + +L     YTV ++A     + P +  +    Q G    P N    
Sbjct: 463  QKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAE 521

Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
              +ET+I ++W+P PR    I ++L  R    G         + S VV  L P  EY + 
Sbjct: 522  ARSETSITLSWSP-PRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFR 580

Query: 1153 IQVLR-DGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERSTTPD-----I 1203
            +      G     P+V +      P +PP ++   +   T +L VSW R   P+     +
Sbjct: 581  LAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL-VSW-RPPPPETHNGAL 638

Query: 1204 TGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPI 1259
             GY +   P   +     E   +    +    + L    +Y ++      V    ES P+
Sbjct: 639  VGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPV 698

Query: 1260 ---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEED-- 1310
               +D  +P+ PP   +    +    +RV W +P P      +  + V Y  ++  E   
Sbjct: 699  VVRTDEDVPSAPP-RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARG 757

Query: 1311 ---VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR----QKTGLDSPTG 1363
               + ++ ++ +   +V+TNL P T Y ++V++   + +    + +    +   L  PT 
Sbjct: 758  PPRIKDVMLADAQE-MVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPT- 815

Query: 1364 IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
            +        S    W  P  T    + GYR++   E  +     +  P S +  T + + 
Sbjct: 816  LSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLE-FPPSEDRYTASGVH 874

Query: 1420 PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA-ATPTSLLISWDAPAVT 1474
             G  YV  + A +    G E + +L   + T    P+ LE    A+  ++L+ W  P   
Sbjct: 875  KGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPA 934

Query: 1475 VRY-----YRITYGETGGNSPVQEFTVP-----GSKSTATISGLKPGVDYTITVYAVTGR 1524
             R      Y +   E G   P +E  +P     G+++  T+ GLKP   Y + V A T R
Sbjct: 935  ERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRR 994

Query: 1525 GDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW 1562
            G  P S     + YRT +     P   +V  +   S+ + W
Sbjct: 995  GPGPFSP---PVRYRTFLRDQVSPKNFKVKMIMKTSVLLSW 1032



 Score =  111 bits (278), Expect = 7e-24
 Identities = 179/799 (22%), Positives = 328/799 (41%), Gaps = 91/799 (11%)

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
            ++T  + S+      V   T    P    +  VTE TA+S  ++W S + D VS + +EY
Sbjct: 295  NYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEY 354

Query: 755  ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTA 810
            + S+  D P  +    T T  +I  L P  +Y + V  ++  G+    +S++  T +   
Sbjct: 355  K-SKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAP 413

Query: 811  PDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYSPSVE---GSSTELNLPETANS 864
              AP +     +  T+++V+W  P  P   I GYR+ Y+   E   G+  + N+ ++   
Sbjct: 414  ASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSL-L 472

Query: 865  VTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDV 921
             T+  L     Y + + A   V +   S P+ ++ +  G P       P +L+    ++ 
Sbjct: 473  TTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ-QGVP-----GQPMNLRAEARSET 526

Query: 922  KVTIMWTPP-ESAVTGYRVDVIPVNLPGEHGQRL--PISRNTFAEVTGLSPGVTYYFKVF 978
             +T+ W+PP + ++  Y +    +   G+HG+ +       T   V  L P   Y F++ 
Sbjct: 527  SITLSWSPPRQESIIKYEL----LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLA 582

Query: 979  AVS-HGRES-KPLTAQQTTKLD---APTNLQFVNETDSTVLVRWTPP-----RAQITGY- 1027
            A S  G  +  P+  Q+T +      P +++ V+   + +LV W PP        + GY 
Sbjct: 583  ARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYS 642

Query: 1028 -RLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-T 1084
             R     +   +P++ N + P+ ++  L  L+  ++Y ++ VA       P+++ V   T
Sbjct: 643  VRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRT 702

Query: 1085 LQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEA---PR-- 1129
             +   S PP   E   +  T I + W +PAP        G+++     +G EA   PR  
Sbjct: 703  DEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIK 762

Query: 1130 -EVTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
              + +D+  +V++ L P   Y  T+       DG      +V      L  PT L ++  
Sbjct: 763  DVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPT-LSVQQT 821

Query: 1186 PDTGVLTVSWE--RSTTPD-ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLE 1242
            P+ G L   WE    T  D + GYR+     +     +LE     D+ + +  +      
Sbjct: 822  PE-GSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYV 880

Query: 1243 YNVSVYT---VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
            + ++  +   + ++   V       P   P       N    T+ + W PP   +    +
Sbjct: 881  FRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAI 940

Query: 1300 VRYSPV---------KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---S 1347
            V+Y+             E ++   +   ++NA+ L  L P T Y + V +   +     S
Sbjct: 941  VKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFS 1000

Query: 1348 TPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAP--RATITGYRIRHH--PEHFSGRPR 1402
             P+R R       SP       I   S  + W  P    + T Y+I+++       GR  
Sbjct: 1001 PPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTT 1060

Query: 1403 EDRV----PHSRNSITLTN 1417
            +  +    PH+  +  LTN
Sbjct: 1061 KKLITHLKPHTFYNFVLTN 1079



 Score =  103 bits (258), Expect = 1e-21
 Identities = 188/791 (23%), Positives = 299/791 (37%), Gaps = 120/791 (15%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRW--KEATIPGHLNSYTIKGLKPGVV 676
            T +   S  I W++  P  +S Y++ ++ K+  G +  KE         Y+I GL P   
Sbjct: 328  TENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSE 384

Query: 677  YEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSF 736
            YE  + ++   G    +             +  T TGE  P S     +     ++A++ 
Sbjct: 385  YEIWVSAVNSIGQGPPSE------------SVVTRTGEQAPAS--APRNVQARMLSATTM 430

Query: 737  VVSW---VSASDTVSGFRVEYELSEE---GDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
            +V W   V  +  + G+RV Y +  E   G+  ++    S  T+V    LL    Y V V
Sbjct: 431  IVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVG--SLLEDETYTVRV 488

Query: 791  YQISEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP-QAPITGYRIVYS 846
               +  G+  L   I   +Q   P  P +   +   +TSI + WS P Q  I  Y +++ 
Sbjct: 489  LAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFR 548

Query: 847  PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN--QESTPVVIQQETTGTPRS 904
                G         T  S  + DL+P  +Y   + A         TPVV Q+     P +
Sbjct: 549  EGDHGREVGRTFDPT-TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSA 607

Query: 905  DTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P+D++ V V    + + W PP       A+ GY V   P+      G   P  + 
Sbjct: 608  ----PPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPL------GSEDPEPK- 656

Query: 960  TFAEVTGLSPGVTY----------YFKVFAVSH-----GRESKPLTAQQTTKLDAPT--- 1001
               EV G+ P  T            +++  V+H     G ES P+  +  T  D P+   
Sbjct: 657  ---EVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVR--TDEDVPSAPP 711

Query: 1002 ---NLQFVNETDSTVLVRWTPP---RAQITGYRL----TVGLTRRGQPRQYNVG-PSVSK 1050
                 + +N T   VL R   P     QI GY++      G   RG PR  +V      +
Sbjct: 712  RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQE 771

Query: 1051 YPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI--PPYNTEVT-ETTIVI 1105
              + NLQP + Y++++ A  +KG+    K   V T    G+ +  P  + + T E +++ 
Sbjct: 772  MVITNLQPETAYSITVAAYTMKGDGARSKPKVVVT---KGAVLGRPTLSVQQTPEGSLLA 828

Query: 1106 TWTPAPRIGFK--LGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEYVYTIQV-LR 1157
             W P         LG R   G E     A  E          SG+  G  YV+ +    R
Sbjct: 829  RWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSR 888

Query: 1158 DGQERDAPIVNKVV--TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT-- 1213
             G   +A  V  +   TP   P  L    N   G + + W      +  G  +  T    
Sbjct: 889  GGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVR 948

Query: 1214 -NGQQGNSLEEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
              G  G + E  + A      +++ T   L P   Y++ V      +   P S    P V
Sbjct: 949  EAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQV-RAHTRRGPGPFS----PPV 1003

Query: 1268 PPPTDLRFTNIGPDTMRVTWAPPPSIDLT-NFLVRY---SPVKNEEDVAELSISPSDNAV 1323
               T LR   + P   +V      S+ L+  F   Y   +P K + +   L +       
Sbjct: 1004 RYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKK 1062

Query: 1324 VLTNLLPGTEY 1334
            ++T+L P T Y
Sbjct: 1063 LITHLKPHTFY 1073



 Score = 33.5 bits (75), Expect = 2.3
 Identities = 88/400 (22%), Positives = 149/400 (37%), Gaps = 88/400 (22%)

Query: 1644 TPTSLSAQWTPPNVQLTGYR--VRVTPKEKTGPMKEIN---LAPDSSSVVVSGLMVATKY 1698
            T T L A    P+ ++T ++  + V P    G +K++    L  +SS     G     KY
Sbjct: 151  TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQG-----KY 205

Query: 1699 EVSVYALKDTLTSRPAQGVVTTLENVSP-----PRRARVTDATETTIT----------IS 1743
            E           S PA  +   +  V+P     P    +       IT          + 
Sbjct: 206  ECVATNSAGVRYSSPAN-LYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVK 264

Query: 1744 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
            W    E +T    D +P  G+  ++ T   D  +YT                    A SS
Sbjct: 265  WMQGAEDLT--PEDDMPV-GRNVLELTDVKDSANYTCV------------------AMSS 303

Query: 1804 PVVIDASTAID------APSNLRFLATTPNSLLVSWQPPRAR-ITGYIIKYE-KPGSPPR 1855
              VI+A   I       AP        T  S+ ++W       ++ Y+I+Y+ K    P 
Sbjct: 304  LGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPY 363

Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKN---NQKSEPLIGRKKTGQEALSQTTIS 1912
            ++  +     T  +I GL P +EY I+V A+ +      SE ++ R  TG++A +     
Sbjct: 364  QI--KEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTR--TGEQAPAS---- 415

Query: 1913 WAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE---ALKDQQ 1969
             AP    +  + +   +   EEP++             GL RG      +E    + + Q
Sbjct: 416  -APRNVQARMLSATTMIVQWEEPVE-----------PNGLIRGYRVYYTMEPEHPVGNWQ 463

Query: 1970 RHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGD 2009
            +H V + ++T   S+ E       D  +    ++  +VGD
Sbjct: 464  KHNVDDSLLTTVGSLLE-------DETYTVRVLAFTSVGD 496


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score =  149 bits (376), Expect = 3e-35
 Identities = 294/1431 (20%), Positives = 527/1431 (36%), Gaps = 186/1431 (12%)

Query: 607   SSSGPVEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGR 653
             S S  +++ + + P  P S  I           W  P     S I+ YI+  R + S   
Sbjct: 19376 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKR-ETSRPN 19434

Query: 654   WKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
             W + +    + S +++ L  G  Y+ ++ +  +YG                PV +     
Sbjct: 19435 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYG-------------VGDPVFTEPAIA 19481

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLP 769
             +     P       ++ IT     VSW   +D     ++G+ +E   ++  +  +    P
Sbjct: 19482 KNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKP 19541

Query: 770   STATSVNIPDLLPGRKYIVNVYQISE--DGEQSLILSTSQTTAPDAPPDPTV-DQVDDT- 825
                 ++    L  G +Y   V  I++   G+ S     +    P  PP P    +V DT 
Sbjct: 19542 IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTT 19601

Query: 826   --SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT--LSDLQPGVQYN 877
               S+ + W +P     +PI GY +    +   +    NLP+        ++ L    QY 
Sbjct: 19602 RSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQ 19661

Query: 878   ITIYAVEENQESTPVVIQQETTGTPRSDTVPSP----RDLQFVEVTDVKVTI-MWTP--- 929
               +YAV +   S P  +  +    P+   +P       DL+   +    VT+ ++ P   
Sbjct: 19662 FRVYAVNKIGYSDPSDVPDKHY--PKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKG 19719

Query: 930   -PESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSP-GVTYYFKVFAVSHGRES 986
              P   +T  + +V   NL    G  +  +  +TF     ++      Y      S G++ 
Sbjct: 19720 RPPPKITWSKPNV---NLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 19776

Query: 987   KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY 1042
               +  +       P N+     +  +  V W PP     + I  Y +      R      
Sbjct: 19777 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 19836

Query: 1043  NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
                 S + + + NL+    Y   + A               V  +  PG  +      V+
Sbjct: 19837 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 19896

Query: 1100  ETTIVITWTPAPR------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
             +++  I W           IG+ +     +  +  R + S S       LT G EY + +
Sbjct: 19897 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSAKDLTEGKEYTFRV 19955

Query: 1154  QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL-------------------TVS 1194
                 +  E     +  V        +L L+  PD   L                   +VS
Sbjct: 19956 SAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 20015

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD-NLSPGLEYNVSVYTVKDD 1253
             W++   P  T  R++             E    + +   +D   S   +Y +++  V   
Sbjct: 20016 WKKGEDPLATDTRVSV------------ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 20063

Query: 1254  KESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             KE   IS  ++     PT  ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 20064 KEGT-ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 20122

Query: 1310  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1363
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 20123 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 20181

Query: 1364  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 20182 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 20241

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS----DVPRDLEVVAATPTSLLISWDAPAVTV 1475
              G EY   ++A+N        +  +  V+    D P   EV+  T  S+ + W  P    
Sbjct: 20242 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 20301

Query: 1476  RY----YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
              +    Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 20302 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 20361

Query: 1532  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1575
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 20362 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 20421

Query: 1576  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAP 1635
                   P      T+ P  + +TI+          ++ A NP G     V+  V  +P P
Sbjct: 20422 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 20475

Query: 1636  TD-LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVS 1690
                ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V +
Sbjct: 20476 PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 20534

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRT 1746
              L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+ 
Sbjct: 20535 KLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKR 20594

Query: 1747  KTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLN--- 1797
               +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N   
Sbjct: 20595 PVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAG 20653

Query: 1798  ----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1849
                   A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K
Sbjct: 20654 IGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 20713

Query: 1850  PGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
              G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 20714 VGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 20761



 Score =  148 bits (373), Expect = 7e-35
 Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 29220 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 29278

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 29279 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 29328

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 29329 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 29385

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 29386 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 29445

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 29446 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 29505

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 29506 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 29557

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 29558 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 29616

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 29617 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 29674

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 29675 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 29733

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 29734 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 29793

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 29794 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 29853

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 29854 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 29911

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 29912 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 29971

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 29972 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 30031

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 30032 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 30091

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 30092 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 30143

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 30144 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 30202

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 30203 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 30261

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 30262 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 30318

Query: 1629  VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
               T   P +         +   VT +S+S  W+ P      ++TGY +          ++
Sbjct: 30319 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 30378

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
                    ++   V+GL+   +Y+  + A  D   + TS  ++ VV     +  S P    
Sbjct: 30379 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 30438

Query: 1732  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
             +   ++ ++T+ W        + I G+ V+    +G +  +++ K  +  + +TI GL  
Sbjct: 30439 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 30497

Query: 1786  GTDYKIYLYTLNDNARSSP 1804
              T+Y+  ++  N+   S P
Sbjct: 30498 ATEYEFRVFAENETGLSRP 30516



 Score =  138 bits (347), Expect = 7e-32
 Identities = 290/1321 (21%), Positives = 498/1321 (37%), Gaps = 189/1321 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 19790 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 19846

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 19847 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 19891

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 19892 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 19948

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 19949 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 20008

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 20009 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 20066 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 20118

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 20119 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 20177

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 20293

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 20294 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 20353

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 20354 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 20412

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 20413 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 20465

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 20466 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 20515

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 20516 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 20575

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 20576 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 20635

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 20636 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 20695

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 20696 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 20755

Query: 1526  -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 20756 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 20815

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V   P P  +
Sbjct: 20816 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 20873

Query: 1638  LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
             L+ T +T  S++  W  P +    ++T Y V    +++    K  + A       +  V+
Sbjct: 20874 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 20929

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
             GL    +Y   V A  +     P +    V   E  SPP    + D T++T++++W    
Sbjct: 20930 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 20989

Query: 1745  RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
                   ITG+ ++A    + Q     T+K       +  L  G +Y   +  +N   RS+
Sbjct: 20990 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 21047

Query: 1804  P 1804
             P
Sbjct: 21048 P 21048



 Score =  129 bits (323), Expect = 4e-29
 Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)

Query: 612   VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
             VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 13776 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 13834

Query: 659   IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                   ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 13881

Query: 719   SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
              P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 13882 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 13941

Query: 775   VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 13942 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 14001

Query: 829   VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
             + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 14059

Query: 883   VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
             V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 14060 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 14119

Query: 939   VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
             V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 14120 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 14178

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
                T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 14179 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 14238

Query: 1050  KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                   +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 14239 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 14298

Query: 1102  -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
               I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 14299 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 14357

Query: 1151  YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
               ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 14358 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 14411

Query: 1208  ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                 PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 14412 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 14470

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
              I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 14471 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 14530

Query: 1318  PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
               +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 14590

Query: 1369  ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
              TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 14591 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 14648

Query: 1423  EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
             EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 14649 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 14708

Query: 1478  YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
               IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 14709 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 14768

Query: 1509  KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
             +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 14769 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 14828

Query: 1565  SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
               S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 14829 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 14888

Query: 1624  LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
              V   +          AP       VT  S+  +W  P      + GY +       T  
Sbjct: 14889 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 14948

Query: 1675  MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
              +      ++    V GL+    Y   V A       +  P     T  + +SPP     
Sbjct: 14949 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 15008

Query: 1731  RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
             RVTD + TTI + W          I G+ VD          + T K   VR YT+  ++ 
Sbjct: 15009 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 15068

Query: 1786  GTDYKIYLYTLNDNARSSP 1804
             G DYK+ +  +N      P
Sbjct: 15069 GADYKLRVSAVNAAGEGPP 15087



 Score =  129 bits (323), Expect = 4e-29
 Identities = 261/1302 (20%), Positives = 465/1302 (35%), Gaps = 162/1302 (12%)

Query: 716   TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--- 772
             TP  P+  T   V EI+  S  V+W           + Y + +   E +     +T    
Sbjct: 19786 TPGPPVNVT---VKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSK 19842

Query: 773   TSVNIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  + +L  G+ Y   V     Y I + GE    +  SQT  P    D  V  V  +S 
Sbjct: 19843 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV--DLKVRSVSKSSC 19900

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
              + W +P +     I GY + +    E +  +  +   +   +  DL  G +Y   + A 
Sbjct: 19901 SIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAE 19958

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              EN E TP     E T   R D V    DL+ +        + +   E++    ++ +  
Sbjct: 19959 NENGEGTP----SEITVVARDDVVAPDLDLKGLP------DLCYLAKENSNFRLKIPIKG 20008

Query: 944   VNLPGEHGQRL--PISRNTFAEVTGLSPGVTY------------YFKVFAVSHGRESKPL 989
                P    ++   P++ +T   V   +   T             Y        G +   +
Sbjct: 20009 KPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 20068

Query: 990   TAQQTTKLDAPTN-LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNV 1044
             + +   K   PT  ++F   T   + ++W PP+    ++IT Y L    +   +      
Sbjct: 20069 SIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCAS 20128

Query: 1045  GPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKATGVFTTLQ---PGSSIPPYNTEVT 1099
                 + + +  L    EYT  + A    G  E  K+  +        P +  PP   +V 
Sbjct: 20129 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVR 20188

Query: 1100  ETTIVITWTPAPRIG--------FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
               ++ +TWT   + G         +   R S   +   +         V+GLT G+EY +
Sbjct: 20189 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 20248

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTTPD---ITGY 1206
              +  +         + ++ V  L P  P       N     +T+ W          +TGY
Sbjct: 20249 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 20308

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEYNV---------SVYTVKDDKE 1255
              +       +   S  +  H +   C F   +L  G +Y           ++    +  E
Sbjct: 20309 IVEKRDLPSK---SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTE 20365

Query: 1256  SVPISD-----TII--PAVPPPTDLRFTN-IGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
             ++   D     TI+  P +     ++  + I  + + +   P P    +       P   
Sbjct: 20366 TIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP--- 20422

Query: 1308  EEDVAELSISPSDNAVVL--TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD---SPT 1362
               D+ +++ +P+ + + +         EY ++ ++ +     T +   + T LD    P 
Sbjct: 20423 -SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF----GTKVEHVKVTVLDVPGPPG 20477

Query: 1363  GIDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTN 1417
              ++ S+++A   T+ W  P     + I  Y + +            + +   R+    T 
Sbjct: 20478 PVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH--VATK 20535

Query: 1418  LTPGTEYVVSIVALN--GREE----SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L  G EY+  + A+N  G+ E     P+ +  +      P   EV   T  +  +SW  P
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 20595

Query: 1472  A----VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    +  Y +   E      V+    P S     ++GL+ G  Y   V A    G  
Sbjct: 20596 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655

Query: 1528  PASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1580
             P S    S+  +        PS   VTD    S S+ W          +TGY V    K 
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY-VVEHQKV 20714

Query: 1581  GPGPTKTKTAGPDQ--TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL 1638
             G       T G     T+  +  LQ   +Y   + A N +G  +P V      IP    +
Sbjct: 20715 GDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV------IPDVEIV 20768

Query: 1639  KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS------------SS 1686
             +        L A+     V   G  +R+    K  P  E+    D+             S
Sbjct: 20769 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTES 20828

Query: 1687  VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDATETTITISW 1744
               +  +    +Y+   + +     +    G V    L+   P    R TD T+ ++T+ W
Sbjct: 20829 FTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHW 20888

Query: 1745  RTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
                       IT + V+   A  ++    T K    +Y +TGL  G +Y   +   N+  
Sbjct: 20889 DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYG 20948

Query: 1801  RSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1852
                P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY+I+ ++ GS
Sbjct: 20949 IGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS 21008

Query: 1853  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                  +   +    E  +  L  G EYT  V+A+ +  +S P
Sbjct: 21009 DQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAP 21048



 Score =  128 bits (321), Expect = 7e-29
 Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)

Query: 758   EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
             E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 13436 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 13491

Query: 815   PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
              +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 13492 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 13551

Query: 871   QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
               G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 13552 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 13611

Query: 931   E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
             +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 13612 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 13670

Query: 987   KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
             KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 13725

Query: 1020  PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
              +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 13726 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 13778

Query: 1080  GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
              V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 13779 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 13835

Query: 1138  IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
              V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 13836 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 13894

Query: 1187  DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                 +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 13895 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 13953

Query: 1244  NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
                V         K  K + P  I D I P  PP  PT     ++G  ++R+ W  P   
Sbjct: 13954 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 14010

Query: 1292  -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
                 + ++++       +E V      P+    +L  L+ G EY   V +V +  E    
Sbjct: 14011 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 14069

Query: 1347  --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
               S P+  R+K    S P  ++  +IT N+  + W  P     + IT Y +        G
Sbjct: 14070 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 14129

Query: 1400  RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
                 D         T+T LT G+ YV  + A N          E  +L     T    P 
Sbjct: 14130 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 14188

Query: 1453  DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
              L VV  T   + + W+ P       ++ Y I   E  G   V+     G      ++ +
Sbjct: 14189 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 14248

Query: 1509  KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
               G +    V A    G G     ++ +SI   T    P   + VTD     I++ W P 
Sbjct: 14249 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 14308

Query: 1565  ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
                  SP+ GY V   P       +  +      +  + EG+ P  EYV+ V A N  G 
Sbjct: 14309 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 14368

Query: 1621  SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
             S+P  + +   +    D K T    T          + + G ++ +    +  P+  ++ 
Sbjct: 14369 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 14420

Query: 1681  APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
               D   V  S  +      +S + L+   + R   G+ T TLEN                
Sbjct: 14421 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 14479

Query: 1724  VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
               P +  + +D T+++  ++W          I  + ++   A  +T I      +  S+T
Sbjct: 14480 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 14539

Query: 1780  ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
             +  L P  +Y   +  +N          ++  +  D     D P ++     T  ++ ++
Sbjct: 14540 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 14599

Query: 1833  WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
             W+PP     ++I GYII+    G    +        +   T  GLE G EY   V A   
Sbjct: 14600 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 14659

Query: 1889  NQKSEP 1894
                SEP
Sbjct: 14660 AGISEP 14665



 Score =  128 bits (321), Expect = 7e-29
 Identities = 299/1394 (21%), Positives = 524/1394 (37%), Gaps = 194/1394 (13%)

Query: 604   TYPSSSGPVEVFIT----ETPSQP----------NSHPIQWNAPQ---PSHISKYILRWR 646
             T  +SSG    F+T    +TPS P          +S  I W  P     S I  YI+  R
Sbjct: 23014 TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKR 23073

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
                    +       H NS+ I  L+ G  Y  ++ +  +YG             T+ P+
Sbjct: 23074 EATRKS-YAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-------LPAQTADPI 23125

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
                 V        P      +V ++T +S  +SW           ++Y +  +    +  
Sbjct: 23126 KVAEV--------PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW 23177

Query: 767   DLPSTATSVN--IPDLLPGRKYIVNVYQISEDGE---QSL---ILSTSQTTAPDAPP--- 815
                +   S+   I +L  G +Y+  V  ++E G    +SL   I++      PD  P   
Sbjct: 23178 SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFS 23237

Query: 816   DPTVDQVDDTSIVVRWS-RPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP-- 872
               +V    D  I V  S RP+  IT  +          +T +N+ ++ +  TLS  +   
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVTDSLDLTTLSIKETHK 23294

Query: 873   --GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
               G QY IT+  V   + ++  ++  +    P+         ++F +V+   +T+ W PP
Sbjct: 23295 DDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGP-------VKFDDVSAESITLSWNPP 23347

Query: 931   ----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAV-----S 981
                    +T Y V                ++R T  +VT L  G  Y F++FA      S
Sbjct: 23348 LYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTL-KVTKLKTGTEYQFRIFAENRYGQS 23406

Query: 982   HGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTRR 1036
                ES P+ AQ   K   P    F    +  +++++W  P     + + GY L      R
Sbjct: 23407 FALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE--RKER 23464

Query: 1037  GQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI 1091
                    V  ++   +++  +NL+   EY   + A  I G  ++ K +  +    P    
Sbjct: 23465 NSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD-- 23522

Query: 1092  PPYNTE---VTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             PP   E   V    I + WT     G  +       G    +     G  + +  T  +E
Sbjct: 23523 PPGTPEPIMVKRNEITLQWTKPVYDGGSMIT-----GYIVEKRDLPDGRWMKASFTNVIE 23577

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPTNL-------------HLEANP---DTGVL 1191
               +T+  L + Q  +  ++ K     +S P++               +  +P   DT V+
Sbjct: 23578 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVV 23637

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS--------PGLEY 1243
                       D+ G  + T     +    +EE    +  +  F  L          G +Y
Sbjct: 23638 NAGETFRLEADVHGKPLPTIEWL-RGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 23696

Query: 1244  NVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPP---PSIDLTNFL 1299
              +    V   K S P++  ++    PP   ++ T +  +   +TW+PP      D+++++
Sbjct: 23697 ILRASNVAGSK-SFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYV 23755

Query: 1300  VRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVY-----EQHESTPLR 1351
             V     K E      ++  S+   N++ +T LL G EYV  + +V      E  ES P+ 
Sbjct: 23756 VE----KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL 23811

Query: 1352  GRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSG----RPR 1402
              +    L   P  ++ ++I  +S TV W  P     + I GY +       SG    +  
Sbjct: 23812 MKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDR--SGIRWIKCN 23869

Query: 1403  EDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---EESPLLIGQQST----VSDVPRDLE 1455
             + R+   R  + +T LT   EY   + A N     E SP  +  ++         P +  
Sbjct: 23870 KRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAH 23927

Query: 1456  VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV----PGSKSTA-TISGLKP 1510
             +V  T  S+ ++W  P        + Y      +  +E+ +     G + T   IS L  
Sbjct: 23928 IVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTE 23987

Query: 1511  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1567
               +Y I V A+   G   A+S P ++    +++ P ++ +       I V+   S+    
Sbjct: 23988 HQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVRAGGSARIHI 24046

Query: 1568  PVTGY---RVTTTPKNGPGPTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
             P  G     +T + + G    K +   G + T+++I+           +  +N SG    
Sbjct: 24047 PFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 24106

Query: 1624  LVQTAVTTIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINL 1680
              V   V   P  P +L   +V   S    W PP +   G +V+  V  K ++      N+
Sbjct: 24107 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID-GGAKVKNYVIDKRESTRKAYANV 24165

Query: 1681  APDSS--SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDAT 1736
             +   S  S  V  L     Y   V A  +     P + V  V   E  SPP +  +TD +
Sbjct: 24166 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 24225

Query: 1737  ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1792
             +T+ ++ W          + G+ V+  P  G        +  V +  +TGL  G +Y+  
Sbjct: 24226 QTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEKWSIVAESKVCNAVVTGLSSGQEYQFR 24284

Query: 1793  LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1852
             +   N+  +S P V      +  P   + L   P SL + +     +  G  +K E P  
Sbjct: 24285 VKAYNEKGKSDPRV------LGVPVIAKDLTIQP-SLKLPFNTYSIQ-AGEDLKIEIP-- 24334

Query: 1853  PPREVVPRPRPGVT 1866
                 V+ RPRP ++
Sbjct: 24335 ----VIGRPRPNIS 24344



 Score =  128 bits (321), Expect = 7e-29
 Identities = 307/1365 (22%), Positives = 489/1365 (35%), Gaps = 211/1365 (15%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 24078 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 24135

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 24136 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 24195

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 24196 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 24251

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 24252 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 24309

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 24361

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 24362 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 24419

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 24420 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 24476

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 24477 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 24535

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 24536 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 24594

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 24595 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 24651

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 24652 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 24700

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 24701 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 24759

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 24760 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 24819

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 24820 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 24878

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 24879 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 24938

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 24939 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 24998

Query: 1628  AVTTIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP- 1682
             A+     P++ K T  + +S+S  W+ P       + GY V V  KE           P 
Sbjct: 24999 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--KEAAADEWTTCTPPT 25056

Query: 1683  --DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP--------RRA 1730
                     V+ L   T+Y   + A+       PA   G V   E + PP        R+ 
Sbjct: 25057 GLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKV 25116

Query: 1731  RVTDATETT---ITISWR----TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1783
              V  A+ T    +TI  R     K E   G   D       +     +  +V  +     
Sbjct: 25117 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRF----- 25171

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR--- 1837
                 D   Y  TL +N+ S    ++    +D+PS   NL       +S+ +SW+PP    
Sbjct: 25172 ----DSGRYNLTLENNSGSKTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDG 25226

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT--ITGLEPGTEYTIYVIALKNN----- 1889
              A+IT YI++  +     R+         T+ T  I  L+ G  Y   V+A         
Sbjct: 25227 GAKITNYIVEKRET---TRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLP 25283

Query: 1890  -------QKSEPLI--GRKKTGQEALSQTTISWA-PFQDTSE----YIISCHPVGTDEEP 1935
                    + SEP +  GR        +  TI W  P  D       Y++     G+++  
Sbjct: 25284 AETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS 25343

Query: 1936  LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 1980
                +V   +  AT++GLT G  Y   V A+ ++ R   R+  V V
Sbjct: 25344 TCTQVK--TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 25386



 Score =  127 bits (318), Expect = 2e-28
 Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 18305 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 18363

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 18364 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 18423

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 18424 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 18481

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 18482 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 18541

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 18542 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 18600

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 18601 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 18659

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 18660 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 18717

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 18718 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 18774

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 18775 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 18833

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 18834 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 18892

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 18893 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 18946

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 18947 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 19006

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 19007 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 19065

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 19066 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 19115

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 19116 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 19173

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 19174 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 19233

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
                 +  TA     Q E T  GL+   +Y           + + + +TAV   P   P+D
Sbjct: 19234 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 19282

Query: 1638  LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
                    P ++ A+  PP + L+   +  +T K  T           PM  ++   D + 
Sbjct: 19283 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 19335

Query: 1687  V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
             +    G+ +A +  +    L     KD    T+T+  + G       +  L+   PP   
Sbjct: 19336 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 19395

Query: 1731  RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
             ++         +SW    E     IT + VD    +     Q +    + S ++  L  G
Sbjct: 19396 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 19455

Query: 1787  TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
              +Y+  +   N      PV  +   A    D P           T + + VSW+PP    
Sbjct: 19456 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 19515

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
              + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A+      +P
Sbjct: 19516 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 19573



 Score =  125 bits (314), Expect = 5e-28
 Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 20586 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 20644

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 20645 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 20692

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 20693 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 20750

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 20751 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 20807

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 20808 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 20861

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 20862 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 20921

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 20922 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 20980

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 20981 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 21038

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 21039 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 21098

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 21099 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 21158

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 21159 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 21218

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
               T   L+ GLEY   V           I+   I A     VP PP   + T +  D+M 
Sbjct: 21219 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 21276

Query: 1285  VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
             ++W  P S   +  L  +   K    +   ++S +    N    + L  G  Y   V + 
Sbjct: 21277 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 21336

Query: 1342  YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
                 +S P +  +       +D P      +IT ++ T+ W  P  T    IT Y +   
Sbjct: 21337 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 21396

Query: 1394  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
                     + +      N  T++ LT    Y   ++A N        I   S  SD    
Sbjct: 21397 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 21452

Query: 1454  LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
              + V A    + + +    +      +R+    +G   P  E++  G +   T       
Sbjct: 21453 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 21512

Query: 1512  VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
              D++  +           A T    +P        N +  +D+P      + VT+V    
Sbjct: 21513 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 21571

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
               + W P      + +  Y V     +    T   +     T++ +  L    EY+  V 
Sbjct: 21572 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 21630

Query: 1614  AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
             A N  G  +PL    V  +        P + + T +T  S+   W  P+     ++  Y 
Sbjct: 21631 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 21690

Query: 1664  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
             V    K     +K            VSGL    +YE  + A      S P+         
Sbjct: 21691 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 21750

Query: 1719  TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
              T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P
Sbjct: 21751 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 21807

Query: 1774  DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
                    SYTITGL    +YKI +Y +N      P ++
Sbjct: 21808 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 21845



 Score =  123 bits (308), Expect = 2e-27
 Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 19484

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 19485 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 19544

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 19545 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 19604

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 19605 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 19664

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 19665 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 19723

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 19784 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 19841

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 19842 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 19898

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 19899 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 19953

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 19954 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 20010

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 20011 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 20061

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 20062 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 20118

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 20119 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 20178

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 20179 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 20238

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 20239 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 20298

Query: 1563  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 20299 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 20358

Query: 1623  PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
                ++  T I      APT +         L+ +     + L    +   P  K+   K 
Sbjct: 20359 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 20416

Query: 1677  ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
                       +I   P SS + +     AT+ +   Y +  T    ++     VT L+  
Sbjct: 20417 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 20473

Query: 1725  SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
              PP    +++ +    T++W    E         +    +T   +   +  D++S  +  
Sbjct: 20474 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 20533

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
             T L  G +Y   +  +N   +  PV  +    +D       P        T N+  VSW+
Sbjct: 20534 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 20593

Query: 1835  PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
              P     + ITGY ++  +  S       +         +TGL+ G+ Y   V A
Sbjct: 20594 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 20648



 Score =  120 bits (300), Expect = 2e-26
 Identities = 273/1236 (22%), Positives = 459/1236 (37%), Gaps = 166/1236 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 27149

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 27150 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 27205

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 27206 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 27262

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 27263 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 27313

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 27314 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 27372

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 27373 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 27432

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 27433 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 27488

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 27489 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 27548

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 27549 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 27605

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 27606 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 27661

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 27662 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 27720

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 27721 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 27780

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 27781 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 27840

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 27841 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 27900

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T    +P   +
Sbjct: 27901 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 27959

Query: 1638  ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
                       +K  +        Q  P   ++T ++  V  +++     EI     S+S+
Sbjct: 27960 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 28016

Query: 1688  VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
              V     AT+    VY ++    S  A+  +      +P +     R T+ T   +T+ W
Sbjct: 28017 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 28073

Query: 1745  RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
                       IT + ++    +         K + +SYT   L  G +Y+  +  +N   
Sbjct: 28074 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 28133

Query: 1799  ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
                   S PVV     T  DAP        T NS+ ++W  P     + I  YI+ + EK
Sbjct: 28134 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 28193

Query: 1850  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
               +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 28194 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 28229



 Score =  118 bits (295), Expect = 7e-26
 Identities = 345/1615 (21%), Positives = 576/1615 (35%), Gaps = 251/1615 (15%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 28959 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 29017

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 29018 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 29067

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 29068 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 29123

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 29124 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 29181

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 29182 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 29232

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 29233 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 29292

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 29293 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 29352

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 29353 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 29412

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 29413 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 29466

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 29467 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 29526

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 29527 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 29577

Query: 1222  EEVVHADQS-----SCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTIIPAVPP-- 1269
             E  + A ++     S T   +S  +E  +  + V  +      E    SD ++ +  P  
Sbjct: 29578 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 29637

Query: 1270  PTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
             P  L   ++   T+ + W  P       LT +++       E  +  +++ P+     +T
Sbjct: 29638 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 29697

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI-TANSFTVHWIAPRATI 1385
             +L  G +Y+  + +  E+  S P        +     +   D+ T    T+H  A R   
Sbjct: 29698 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVE 29757

Query: 1386  TGYRIRHHPE-----HFSGRPR--------EDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
                 I   P       F+G           E     ++ +I  T +    EY + +  + 
Sbjct: 29758 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 29817

Query: 1433  GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
             G     + +            +++     TS+ ISW+ P            E  G +P+ 
Sbjct: 29818 GTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP------------ELDGGAPLS 29865

Query: 1493  EFTV-------PG--------SKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI 1536
              + V       PG        ++ST   + L  G +Y   V A    G  S   S+ I  
Sbjct: 29866 GYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 29925

Query: 1537  NYRTEIDKPSQ-MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
                  I  P + +Q+ DV  + +++ W P      S VTGY V           +     
Sbjct: 29926 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 29985

Query: 1592  PDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA-PTDLKFTQVT 1644
                T     GL   +EY   V A N      PS  S+P+V       P  P + + T  T
Sbjct: 29986 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 30045

Query: 1645  PTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
              TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y  
Sbjct: 30046 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 30105

Query: 1701  SVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTE 1749
              V A        PA+  G V   E +  P             V       +TI  + K  
Sbjct: 30106 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP- 30164

Query: 1750  TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVI 1807
                 F +      GQ   +R +     ++T   ++     D   Y   L +      V I
Sbjct: 30165 ----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 30220

Query: 1808  DASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVV 1858
                  I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    + 
Sbjct: 30221 KVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTID 30279

Query: 1859  PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA------------- 1905
              R R   T   + GL+   EY   V A      S+PL   +    +              
Sbjct: 30280 SRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPE 30337

Query: 1906  -----LSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 1955
                   S  ++SW+  +D      + Y I      TD+     +   T+T  T+TGL   
Sbjct: 30338 VLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPD 30397

Query: 1956  ATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2012
             A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V  +WE
Sbjct: 30398 AEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWE 30452

Query: 2013  RMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2067
             +    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 30453 KPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 30499



 Score =  117 bits (294), Expect = 9e-26
 Identities = 153/711 (21%), Positives = 271/711 (38%), Gaps = 74/711 (10%)

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
             PP   ++   I   ++ ++W PP       L+ ++V      +      +S S + +   
Sbjct: 29834 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 29892

Query: 1325  LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              T L  G EYV  V++        Y Q E    R   +     P  +   D++ +  T+ 
Sbjct: 29893 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 29951

Query: 1378  WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
             W  P     + +TGY +           R ++VP +      T LT G EY   + A+N 
Sbjct: 29952 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 30011

Query: 1434  R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
             R          P++          P++  V   T TS+ ++W  P       V  Y I  
Sbjct: 30012 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 30071

Query: 1483  GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
              +   +   +  T P      T++ L  G +Y   V A    G    +  P ++     +
Sbjct: 30072 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 30131

Query: 1543  DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
             + P   ++ +     I V+    +  + P+ G  + +    K G   +K       +T  
Sbjct: 30132 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 30190

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
             E+ I+           +  +N  G+    ++  V   P   +  L++  +   S+   W 
Sbjct: 30191 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 30250

Query: 1654  PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
             PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A   
Sbjct: 30251 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 30307

Query: 1708  TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
                S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ ++
Sbjct: 30308 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 30367

Query: 1758  AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
                 +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  D
Sbjct: 30368 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 30426

Query: 1809  ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
                    P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R  
Sbjct: 30427 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 30486

Query: 1865  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAP 1915
               + TI GL   TEY   V A      S P    ++T     ++ T   AP
Sbjct: 30487 DKQFTIGGLLEATEYEFRVFAENETGLSRP----RRTAMSIKTKLTSGEAP 30533



 Score =  116 bits (291), Expect = 2e-25
 Identities = 283/1346 (21%), Positives = 478/1346 (35%), Gaps = 213/1346 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 24153

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 24154 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 24200

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 24201 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 24256

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 24257 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 24316

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 24317 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 24375

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 24428

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 24429 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 24487

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 24605

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 24606 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 24659

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 24660 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 24719

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAV-PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 24779 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 24837

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 24838 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 25017

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 25018 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 25065

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 25066 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 25121

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 25122 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 25178

Query: 1613  YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
               +N SG     V   V   P AP +L   +V   S++  W PP      ++T Y   + 
Sbjct: 25179 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 25235

Query: 1668  PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
              K +T       +  + +     +  L     Y   V A  +     PA+    V   E 
Sbjct: 25236 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 25295

Query: 1724  VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
               PP R  + D T  T TI W  K E+     ITG+ V+ +   G        +      
Sbjct: 25296 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 25353

Query: 1779  TITGLQPGTDYKIYLYTLNDNARSSP 1804
             TI+GL  G +Y   +  +N+  RS P
Sbjct: 25354 TISGLTAGEEYVFRVAAVNEKGRSDP 25379



 Score =  115 bits (289), Expect = 4e-25
 Identities = 310/1459 (21%), Positives = 503/1459 (34%), Gaps = 214/1459 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 24772 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 24826

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 24827 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 24884

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 24885 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 24943

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 24944 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 24997

Query: 905   DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 24998 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 25057

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
             L G+              VT L     Y F++ A++     +P T      AQ+  +   
Sbjct: 25058 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 25106

Query: 997   --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
               LDA      V    +T+ +  T    P  ++   +    LT R Q     V  S +  
Sbjct: 25107 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 25163

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 25164 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 25223

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 25224 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 25339

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
             ++ ++  +V   +    T   L+ G EY   V  V +   S P  +   +I     + P 
Sbjct: 25340 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 25396

Query: 1271  TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
              +L F               P        V +              V + + V  LSI  
Sbjct: 25397 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 25456

Query: 1319  SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
             +    V      GT  +   +S         +    + G   P  ID  +++ +S T+ W
Sbjct: 25457 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 25508

Query: 1379  IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
               P       I+ Y I    E  S          +R SI +  LT G+EY   + A N  
Sbjct: 25509 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 25567

Query: 1434  -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
                   E S ++     +    P   +VV AT +++L++W  P       V  Y + Y E
Sbjct: 25568 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 25627

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
                    +   +  + +   +SGL  G+ Y   VYA  + G G    S +P+    R   
Sbjct: 25628 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 25685

Query: 1543  DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
             D P Q +VT++   S+S+KW        + +TGY V           K       +T   
Sbjct: 25686 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 25745

Query: 1599  IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
             +  L     Y   V+A+N       PS  + P +V+  V       D+KF  V     + 
Sbjct: 25746 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 25804

Query: 1651  QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
             +    N  + G  + V    K G   E       ++ D+ +++     +       V  L
Sbjct: 25805 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 25864

Query: 1706  KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
             K+   +R        L+   PP     +   T    ++SW    E   G  +D   V   
Sbjct: 25865 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 25923

Query: 1763  GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
               + +  TI   +  + S  +T L  G +Y   +  +N      P+       +D  T  
Sbjct: 25924 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 25983

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               P++L   + T  S+ + W  P     + I+GYII+  +  S     V +         
Sbjct: 25984 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 26043

Query: 1870  ITGLEPGTEYTIYVIA-----LKNNQKSEPLI------------GRKKTGQEALSQTTIS 1912
              TGL  G EY   V A     L    ++ PLI             + K      +  TI+
Sbjct: 26044 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIA 26103

Query: 1913  WA-PFQDTSEYIISCHPVGTDEEPLQFRVPGTS---TSATLTGLTRGATYNIIVEAL--- 1965
             W  P  D    I          +   ++    S   T  T++GLT GA Y   V+++   
Sbjct: 26104 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 26163

Query: 1966  --------KDQQRHKVREE 1976
                      D Q  K REE
Sbjct: 26164 GASDPSDSSDPQIAKEREE 26182



 Score =  115 bits (288), Expect = 5e-25
 Identities = 283/1405 (20%), Positives = 509/1405 (36%), Gaps = 159/1405 (11%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 24803 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 24861

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 24862 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 24908

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 24909 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 24967

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 24968 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 25027

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 25028 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 25087

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 25088 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 25147

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 25148 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 25204

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 25205 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 25264

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 25265 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 25321

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 25322 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 25381

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 25382 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 25434

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAVPPPTDL 1273
             L+E    + SS    T  ++    + +V  Y +         +VPI+  ++    PP  +
Sbjct: 25435 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 25494

Query: 1274  RFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTN 1327
             R   +  D++ ++W PP       ++N++V     K E        +S + +  ++ +  
Sbjct: 25495 RIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVR 25550

Query: 1328  LLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP 1381
             L  G+EY   V +          ES+ +          P G       T ++  V W  P
Sbjct: 25551 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 25610

Query: 1382  ----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----G 1433
                  + + GY + +         + +++  +   + ++ L  G  Y   + A N    G
Sbjct: 25611 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 25670

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             +              D P   EV   T  S+ + W  P       +  Y +   E     
Sbjct: 25671 KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGR 25730

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQM 1548
              ++       ++   ++ L     Y   V+A       S  S     I  + +++ P  M
Sbjct: 25731 WLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVM 25790

Query: 1549  QVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIE 1600
                  +D  +  + + L  ++ + G    V +  K+G       +T+    D  T +T++
Sbjct: 25791 MDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK 25850

Query: 1601  GL--QPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT--DLKFTQVTPTSLSAQWTPP- 1655
                 + T +YV+++  +N +G     V   V   P P    L+   +T    S  W  P 
Sbjct: 25851 DCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 25908

Query: 1656  ---NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLT 1710
                   +  Y   +  K +T  +       +   +S  V+ L+   +Y   V  +     
Sbjct: 25909 EDGGADIDYY---IVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 25965

Query: 1711  SRPAQGV-VTTLENV---SPPRRARVTDATETTITISW-RTKTE---TITGFQVDAVPAN 1762
               P + V +  L+     SPP    +T  T+ ++T+ W R +++    I+G+ ++    N
Sbjct: 25966 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 26025

Query: 1763  GQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAI--- 1813
                 ++   KP  D+R  + TGL+ G +Y+  +Y  N    S P     +I A   +   
Sbjct: 26026 SLRWVRVNKKPVYDLRVKS-TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 26084

Query: 1814  DAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               PS  + + +   ++ ++W  P     A ITGY ++Y+K      +   +   G TE T
Sbjct: 26085 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 26143

Query: 1870  ITGLEPGTEYTIYVIALKNNQKSEP 1894
             I+GL  G EY   V ++     S+P
Sbjct: 26144 ISGLTTGAEYVFRVKSVNKVGASDP 26168



 Score =  112 bits (281), Expect = 3e-24
 Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 20473 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 20527

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 20528 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 20574

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 20575 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 20634

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 20635 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 20694

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 20695 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 20753

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 20754 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 20813

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 20814 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 20870

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 20871 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 20929

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 20930 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 20988

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 20989 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 21047

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 21048 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 21104

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 21105 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 21164

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 21165 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 21223

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 21224 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 21283

Query: 1383  AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
             +     I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 21284 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 21343

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 21344 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 21400

Query: 1492  QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +      +      T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 21401 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 21460

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 21461 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 21513

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
                  +             ++ A NP G ++ +    V   P P +  L  T+VT     
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 21573

Query: 1650  AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
               W PP      ++  Y V+   K +T  +   N+A +   + + V+ L+   +Y     
Sbjct: 21574 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 21630

Query: 1699  EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
              V+ Y + + L S P   V        PP+   VT  T+ ++ + W           ++ 
Sbjct: 21631 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 21689

Query: 1759  VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
             +        QR IK + ++     Y ++GL  G +Y+  +   N    S+P         
Sbjct: 21690 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 21749

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
              D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V  P 
Sbjct: 21750 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 21809

Query: 1863  P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
                 T  TITGL    EY I + A+ +    EP +
Sbjct: 21810 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 21844



 Score =  110 bits (275), Expect = 2e-23
 Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)

Query: 709   NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
             N V     P  P+     S  E+T    V+SW    D   G ++   + E+ +  + + +
Sbjct: 16907 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 16960

Query: 769   PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
             P T+    T+  +  LL G+ YI      N+Y IS+      + +  +   PDAP  P V
Sbjct: 16961 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 17020

Query: 820   DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
              +V   S +V W++P     PIT Y +    ++      +            + DL  G 
Sbjct: 17021 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 17080

Query: 875   QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             QY   + A  E     P    +             P + + ++ T   V + W PP    
Sbjct: 17081 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 17140

Query: 932   -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
              S + GY V+   V +         P S   T  +VTGL  G TY F+V AV+   ES P
Sbjct: 17141 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 17200

Query: 989   LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
                 +      +L+ P  +   N      +      R  A I G    ++T     R  P
Sbjct: 17201 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 17260

Query: 1040  RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
              +   +V P  SK  +RN         SL           +  V    +PG   PP + E
Sbjct: 17261 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 17317

Query: 1098  VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
             V+E    +  +TW      G      + +  R     + +P   TS   S     L  G 
Sbjct: 17318 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 17377

Query: 1148  EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
             +Y++  +V  + Q    P V      K + PL    PP +LH   + D   +++ W   +
Sbjct: 17378 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 17434

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
             R     ITGY +       Q     + V + +   C    L  G  Y   V    ++   
Sbjct: 17435 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 17489

Query: 1257  VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
             + + DT IP       VPP  +L    I         T+R    +   P P+   T    
Sbjct: 17490 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 17546

Query: 1301  RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
               S +K +E     + + S    +   L   T EY ++VS+       +       T LD
Sbjct: 17547 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 17602

Query: 1360  ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
                 PTG I+  D+T    T+ W  P+       I +  E    R     V  S +S T 
Sbjct: 17603 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 17662

Query: 1415  --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
               + +L  G EYV  + A N        + +P +   + +    P    V   T  +  +
Sbjct: 17663 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 17722

Query: 1467  SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             SW  P     +    YY      TG    V +  +   K   T  GL  G  Y   V+A 
Sbjct: 17723 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 17780

Query: 1522  TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
                G S  S     I     I  P      ++ D    +  + W        SP+ GY V
Sbjct: 17781 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 17840

Query: 1575  TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
                    PG  +      D    Q    + GL    EY   + A N  GE +P  L ++ 
Sbjct: 17841 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 17897

Query: 1629  VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
             +   I  P +++   VT   +        +++   RV+  P+      K G +    K +
Sbjct: 17898 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 17955

Query: 1679  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
             +L  D   V +  +  A + +   Y +    +S  AQG  +V  L+   P +  +VT+ T
Sbjct: 17956 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 18014

Query: 1737  ETTITISWRTKTET----ITGFQVD 1757
             +   TISW    +     IT F V+
Sbjct: 18015 KENCTISWENPLDNGGSEITNFIVE 18039



 Score =  110 bits (274), Expect = 2e-23
 Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
             +T++T  S +++W    D        Y +     D   +  L ST    N     L+P +
Sbjct: 13792 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 13851

Query: 785   KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
             +YI      N+Y + E  + S I +  Q   P  P       +   ++ + W  P     
Sbjct: 13852 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 13911

Query: 836   APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
             +PITGY +    P  +       +P    +  +  L    +Y   + A       +  +S
Sbjct: 13912 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 13971

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
             T  ++ ++    P     P+ +D     V    V + WT PE    + +  Y ++++   
Sbjct: 13972 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 14026

Query: 946   LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
                     + +P +++    + GL  G  Y F+V AV+   ES+P       L  ++   
Sbjct: 14027 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 14083

Query: 997   LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
                P  L+ +N T +T  ++WT P     + IT Y +     RR   +  +     +K  
Sbjct: 14084 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 14143

Query: 1053  LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
             +  L   S Y   + A            ++S  A   FTT  PG   PPY   V + T  
Sbjct: 14144 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 14198

Query: 1103  -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
              + + W P    G +            LG R  + G+          +  V+ +  G E 
Sbjct: 14199 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 14254

Query: 1150  VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
              + ++   +       +  +   +    +P SPP +LH+    D G   + ++W   E++
Sbjct: 14255 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 14311

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                 I GY +   P   ++   +      D      + + P  EY + V  V     S P
Sbjct: 14312 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 14371

Query: 1259  --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
               IS+ ++   P   P  DL   +I          P   R    P  S       V+ S 
Sbjct: 14372 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 14431

Query: 1305  ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
                +KN+   A L +  S  A      + L N L      ++V  +              
Sbjct: 14432 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 14477

Query: 1356  TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
              GL  P   I  SDIT +S  + W  P     G  I H+        R   +P     ++
Sbjct: 14478 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 14535

Query: 1411  NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
              S T+ +L P  EY   + A+N   G E    ++P++        D P D+EV   T  +
Sbjct: 14536 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 14595

Query: 1464  LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
             + I+W  P       +  Y   +I  GE        E  VP    T T  GL+ G +Y  
Sbjct: 14596 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 14652

Query: 1517  TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
              V A    G S  S           ID P  +  T ++         D SIS      + 
Sbjct: 14653 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 14712

Query: 1562  WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
             W+   + +    +    K    P   +  G  Q E                         
Sbjct: 14713 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 14768

Query: 1600  -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
              + L+P    +  +  +N  G ++ P   + + T   P +  F  +  TS+  +W PP  
Sbjct: 14769 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 14827

Query: 1656  --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
                 ++  Y +    K K          PDS  +VV+  +   KY V+       Y  + 
Sbjct: 14828 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 14877

Query: 1708  TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
                +R   G   V   L    P      P +  V D T  ++ + W    +    I G+ 
Sbjct: 14878 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 14937

Query: 1756  VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
             ++    N    + + +++   +++  + GL  G  Y   +   N     + SP   D  T
Sbjct: 14938 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 14995

Query: 1812  AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
             A D      P   R   T+  ++ + W+PP       I GY +  +  G+          
Sbjct: 14996 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 15055

Query: 1863  PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
               V + T+  +  G +Y + V A+    +  P
Sbjct: 15056 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 15087



 Score =  109 bits (273), Expect = 3e-23
 Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)

Query: 766   LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
             +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 13045 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 13104

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
              + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 13105 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 13163

Query: 880   IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
             + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 13164 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 13223

Query: 936   GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
              Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 13224 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 13283

Query: 996   KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
             K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 13284 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 13341

Query: 1041  QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
                + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 13342 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 13400

Query: 1095  NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
                +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 13401 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 13460

Query: 1147  VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
              + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 13461 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 13515

Query: 1203  ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
                +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 13516 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573

Query: 1258  PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
              + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 13633

Query: 1310  DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
              VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 13634 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 13687

Query: 1370  TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                   V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 13688 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 13744

Query: 1423  EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
             +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 13745 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 13804

Query: 1469  DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 13805 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 13857

Query: 1519  YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
              A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 13858 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 13917

Query: 1573  RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
              V     +     +        T   ++GL    +Y   V A+N +G  +P   T    I
Sbjct: 13918 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 13977

Query: 1633  PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
               P D  +    P       TS+   WT P      ++  Y + +    KTG  + + +A
Sbjct: 13978 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 14034

Query: 1682  P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
                 ++  ++ GLM   +Y   V A+     S P++    V   E +   SPPR   V +
Sbjct: 14035 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 14094

Query: 1735  ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
              T+ T  + W    +     IT + V+   V   G   +  T+K      T+T L  G+ 
Sbjct: 14095 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 14152

Query: 1789  YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
             Y   +   N   +S       S +  D  T    P  L  +  T   + + W+PP+
Sbjct: 14153 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 14208



 Score =  109 bits (273), Expect = 3e-23
 Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)

Query: 692   VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
             VTRFD    S    +T    +G  T F       SP    + ++ E+   S  +SW    
Sbjct: 25168 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 25223

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
             +     ++ + VE     E     Y  + +  T T+  I +L  G  Y   V   +E G 
Sbjct: 25224 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280

Query: 799   QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
               L   T++      PP P    T+  V   +  ++W +P++     ITGY  V     +
Sbjct: 25281 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 25337

Query: 851   GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
             GS       +      T+S L  G +Y   + AV E   S P      VI ++    P  
Sbjct: 25338 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 25395

Query: 905   DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
              +V  P     V+  + +K+ + +     A   +R D          GQ L     ++ +
Sbjct: 25396 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 25444

Query: 960   TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
             +   VT LS        V  Y    + S G  + P+T     +   P  ++    +  ++
Sbjct: 25445 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 25504

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
              + W PP      QI+ Y   V          + V  +V++  ++   L   SEY   + 
Sbjct: 25505 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 25562

Query: 1068  AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
             A          ES      +    PG    P     T++T+++TW           IG+ 
Sbjct: 25563 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 25622

Query: 1117  LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
             L  +        +A + + +D+  + VSGL  G+ Y   VY   +   G+   +      
Sbjct: 25623 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 25681

Query: 1171  VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
               P  PP     TN+  ++        + D G     +  ER   PD  G  +    TN 
Sbjct: 25682 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 25739

Query: 1216  QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
             Q+       +  DQ       +    D++S   E +     VKDD E       V   D 
Sbjct: 25740 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 25798

Query: 1263  IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
             I+        +     G     ++WA    I++             E+ A   I  +DN 
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 25844

Query: 1323  VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
              +LT          +YV+++ +V      +   +   K G   P G ++ + +TA   ++
Sbjct: 25845 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 25902

Query: 1377  HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
              W  P+    A I  Y + +    H +    E  +     S  +T L  G EY+  +  +
Sbjct: 25903 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 25960

Query: 1432  NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
             N        E   +      TV   P  LE+ + T  S+ + W  P       +  Y I 
Sbjct: 25961 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 26020

Query: 1482  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
               E      V+    P        +GL+ G +Y   VYA    G S P+ + P+ I    
Sbjct: 26021 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 26079

Query: 1541  EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
              +     PS+ ++ D    +I++ W+       +P+TGY V    K+     KT      
Sbjct: 26080 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 26138

Query: 1594  QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
              TE TI GL    EYV  V + N      PS  S P +       P     ++++ T + 
Sbjct: 26139 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 26198

Query: 1645  PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
                 S   T P      +R R  P           +T    +   +  S ++  +    +
Sbjct: 26199 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 26252

Query: 1696  TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
              KY +++   ++ L++     VV  L+   PP    V D T+ +  +SW          +
Sbjct: 26253 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 26309

Query: 1752  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
               + ++   A+ +  +  T   +  SY +T LQ G  Y   +   N+     P       
Sbjct: 26310 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 26369

Query: 1812  AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
              I      P  L   + + +S+ ++W  P     +RI  Y+++  + G   +  V     
Sbjct: 26370 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 26427

Query: 1864  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
               T   ++GL   +EY   V A      S+P
Sbjct: 26428 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 26458



 Score =  108 bits (271), Expect = 4e-23
 Identities = 280/1299 (21%), Positives = 479/1299 (36%), Gaps = 170/1299 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 21563 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 21680

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 21681 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 21739

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 21796

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 21797 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 21856

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 21857 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 21907

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 21908 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 21967

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 21968 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 22024

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 22025 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 22082

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 22083 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 22139

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 22140 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 22193

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 22194 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 22251

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 22252 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 22310

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 22311 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 22369

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 22370 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 22429

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 22430 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 22489

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
                   T   + GL     Y   V A+N +G  S+P   T   T     D         S
Sbjct: 22490 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 22544

Query: 1648  LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
             +  ++    V   G   +V       P+  I          +++ + +     AT   V 
Sbjct: 22545 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 22604

Query: 1702  ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
                       +   K+    R     V  L+   PP     ++  T    T++W+   + 
Sbjct: 22605 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 22664

Query: 1751  ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
                  ++ +    +T   +   +  +V+  S  +T L  G +Y   +     Y + +   
Sbjct: 22665 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 22724

Query: 1802  SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
             S PVV      + DAP        T +S++V W+ P     + I GY++ K +K G    
Sbjct: 22725 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 22784

Query: 1856  EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 R   G     +TGL    +Y   V A      SEP
Sbjct: 22785 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 22822



 Score =  105 bits (261), Expect = 6e-22
 Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 16229 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 16288

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 16289 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 16348

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 16349 TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 16406

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 16407 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 16466

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 16467 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 16526

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 16527 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 16580

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 16581 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 16640

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 16641 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 16700

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 16701 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 16759

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 16760 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 16816

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
             PPT          +R       T R +  P P +         S  K+E DV E     +
Sbjct: 16817 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 16867

Query: 1315  SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
               +P+  A+          G   VV  +S   +     +    + G   P G + F ++T
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 16925

Query: 1371  ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
              +   + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+ 
Sbjct: 16926 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 16984

Query: 1427  SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
              I A N    S  L+           V D P    V   T  S L++W+ P         
Sbjct: 16985 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 17044

Query: 1472  -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
                     ++ R+ R+T        P  +F VP          L  G  Y   V A    
Sbjct: 17045 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 17092

Query: 1523  GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
             G GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY + 
Sbjct: 17093 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 17149

Query: 1576  TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
                K G    +     P+   +T+  + GL+    Y   V A N +GES P        +
Sbjct: 17150 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 17203

Query: 1633  PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
             P P  +K     P   L A          G  +R++      P  K    KE   AP  +
Sbjct: 17204 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 17263

Query: 1686  SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
              + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR   V++ 
Sbjct: 17264 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 17321

Query: 1736  TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
              + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    L  G  Y
Sbjct: 17322 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 17379

Query: 1790  KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
                +   N   R   V        +D       P +L  +      + + W  P     +
Sbjct: 17380 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 17439

Query: 1839  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
              ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K+E ++G
Sbjct: 17440 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 17489



 Score =  103 bits (257), Expect = 2e-21
 Identities = 257/1326 (19%), Positives = 466/1326 (35%), Gaps = 204/1326 (15%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 19372 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 19431

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 19432 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 19489

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 19490 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 19548

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 19549 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 19608

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 19609 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 19668

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 19669 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 19721

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 19722 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 19779

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 19780 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 19834

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPAVPPPTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 19835 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 19890

Query: 1274  RFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
             +  ++   +  + W  P S     +  ++V +   +N+      S+S   +A  LT    
Sbjct: 19891 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE--- 19947

Query: 1331  GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI----T 1386
             G EY   VS+  E  E TP            T +   D+ A    +  +     +    +
Sbjct: 19948 GKEYTFRVSAENENGEGTP---------SEITVVARDDVVAPDLDLKGLPDLCYLAKENS 19998

Query: 1387  GYRIR-----HHPEHFSGRPRED------RVPHSRNSITLTNL------TPGTEYVVSIV 1429
              +R++           S +  ED      RV    +++  T +      +   +Y +++ 
Sbjct: 19999 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 20058

Query: 1430  ALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1485
              + G +E  + I            ++    T  ++ + W  P       +  Y +   ++
Sbjct: 20059 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 20118

Query: 1486  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTEI-D 1543
               N  V   +    K+T  ++ L  G++YT  V A    G      S+PI   +  ++ D
Sbjct: 20119 VNNKWVTCASAV-QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 20177

Query: 1544  KPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1599
              P    + DV+ +S+S+ W        SP+TGY +    +N     +         +  +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
              GL   +EY   V A N +G  +P + +    A+  I  P   +   +T  S++  WT P
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP 20297

Query: 1656  NV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL-- 1709
                   +LTGY V          MK  ++     +  V+ L+   KYE  + A K+T   
Sbjct: 20298 KYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRA-KNTAGA 20356

Query: 1710  TSRPAQGVVTTLEN---------VSPPRRARVTDATETTITI-------------SWRTK 1747
              S P++   T +           + P  +  +T     TI +             SW   
Sbjct: 20357 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 20416

Query: 1748  TETITGF---QVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYLYTLNDNARSS 1803
              + I      Q+ + P +    I+   + D   YTIT   P GT  +    T+ D     
Sbjct: 20417 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLD----- 20471

Query: 1804  PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1859
                         P  +     +     ++W PP     + I  YI++  +       VV 
Sbjct: 20472 --------VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS 20523

Query: 1860  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG----------------RKKTGQ 1903
                        T L  G EY   V A+ +  K EP+                  + +   
Sbjct: 20524 EDIQSCRHVA-TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSN 20582

Query: 1904  EALSQTTISWA-PFQDTSEYIISCHPVGTDEEPLQF----RVPGTSTSATLTGLTRGATY 1958
                +  T+SW  P  D    I   H    +++ L++    + P +     +TGL  G+TY
Sbjct: 20583 VTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTY 20642

Query: 1959  NIIVEA 1964
                V A
Sbjct: 20643 EFRVSA 20648



 Score =  102 bits (255), Expect = 3e-21
 Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 16635 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 16693

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 16694 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 16741

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 16742 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 16801

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 16802 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 16862 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 16919

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 16920 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 16975

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 16976 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 17035

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 17036 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 17095

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 17096 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 17153

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 17154 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 17213

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 17214 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 17272

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 17273 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 17318

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 17319 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 17377

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 17378 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 17436

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 17437 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 17494

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 17495 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 17546

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 17547 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 17598

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 17599 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 17655

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T        + P+P      T +
Sbjct: 17656 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 17715

Query: 1644  TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
             T  + +  WT P       +TGY +    +E TG    +N  P +     V+GL     Y
Sbjct: 17716 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 17773

Query: 1699  EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
             E  V+A      S+P+           ++   PP   ++ D +  T  + W TK      
Sbjct: 17774 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 17832

Query: 1749  ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
               I G+ V+     G     R  K ++    ++ + GL  G +Y+  +   N      P
Sbjct: 17833 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 17890



 Score =  101 bits (252), Expect = 7e-21
 Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 28166 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 28224

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 28225 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 28272

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 28273 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 28332

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 28333 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 28392

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 28393 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 28451

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 28452 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 28507

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 28508 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 28566

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 28567 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 28624

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 28625 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 28679

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 28680 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 28739

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 28740 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 28799

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 28800 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 28856

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 28857 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 28915

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 28973

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 28974 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 29031

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 29032 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 29091

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 29092 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 29148

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 29149 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 29196

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
             + YVV+           V A N  G     ES+P+V     TIP+P  +     T    +
Sbjct: 29197 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 29256

Query: 1649  SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
               QWT P      +++ Y V    K +   ++   +  D     + + V+ LM    Y+ 
Sbjct: 29257 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 29313

Query: 1701  SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
              V A+     S P  A   ++  E      PP   RV D T+ +I+++W
Sbjct: 29314 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 29362



 Score =  101 bits (251), Expect = 9e-21
 Identities = 274/1343 (20%), Positives = 479/1343 (35%), Gaps = 185/1343 (13%)

Query: 692   VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
             V R+D   +T T  ++  T +         +P    +  VTEIT  S  ++W    +   
Sbjct: 23003 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 23062

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
               +  + VE     E     Y  + +     S  I  L  G  Y   V   +E G     
Sbjct: 23063 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 23119

Query: 803   LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
              +       + P  P   TVD V   S+ + W++P+       I Y   ++   +E    
Sbjct: 23120 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 23178

Query: 860   ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
             E A        +++L  G +Y   + AV E   S P           +VI+ +      S
Sbjct: 23179 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 23238

Query: 905   DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
              +V   +DL+ +EV      K TI WT           D +P+       Q   I+    
Sbjct: 23239 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 23281

Query: 962   AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
              ++T LS   T+      Y    A   G+++  +      K D P   ++F + +  ++ 
Sbjct: 23282 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 23341

Query: 1015  VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
             + W PP      QIT Y +    T        +   + +   +  L+  +EY   + A  
Sbjct: 23342 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 23401

Query: 1071  --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
               G     ES      +   +PG    P+ T +++ ++VI W        +P IG+ L  
Sbjct: 23402 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 23461

Query: 1120  RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
             +        +  + +  D+       L  G+EY + +       V +  +  +  +    
Sbjct: 23462 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 23520

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
               P   P  + ++ N     +T+ W +        ITGY +     P       S   V+
Sbjct: 23521 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 23576

Query: 1226  HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
                ++  T   L+    Y   V          K    + PI+   +  +P +   P   D
Sbjct: 23577 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 23633

Query: 1273  LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
                 N G +T R    V   P P+I+           K  E+ A   I  +D   +L   
Sbjct: 23634 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 23686

Query: 1326  -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
                 + G +Y++  S+V    +S P+  +       P G +  + +T+   ++ W +P  
Sbjct: 23687 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 23744

Query: 1384  TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALN------G 1433
                G  I H+   +  + R     V      NS+ +T L  G EYV  I+A+N       
Sbjct: 23745 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 23804

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
              E +P+L+     +   P+ LEV      S+ + W+ P        I Y  E    S ++
Sbjct: 23805 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 23864

Query: 1493  EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
                    + T     ++GL    +Y   V A    G    S  P ++ Y+      +   
Sbjct: 23865 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 23922

Query: 1545  PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN-GPGPTKTKTAGPDQTEMTI 1599
             P+   + D   NSI++ W        S + GY V     +       T   G   T   I
Sbjct: 23923 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 23982

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
               L    EY + V A N  G  +    T+V     P D    +     L ++     V  
Sbjct: 23983 SKLTEHQEYKIRVCALNKVGLGE---ATSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 24037

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
              G   R+    K  P  EI  + +    +  V +   +  T+  +           +  L
Sbjct: 24038 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 24097

Query: 1706  KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
             +++  S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +
Sbjct: 24098 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 24157

Query: 1762  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
               +     + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS   
Sbjct: 24158 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 24217

Query: 1818  NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1873
              +     +  S  + W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL
Sbjct: 24218 KVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGL 24275

Query: 1874  EPGTEYTIYVIALKNNQKSEPLI 1896
               G EY   V A     KS+P +
Sbjct: 24276 SSGQEYQFRVKAYNEKGKSDPRV 24298



 Score =  100 bits (250), Expect = 1e-20
 Identities = 283/1422 (19%), Positives = 504/1422 (35%), Gaps = 178/1422 (12%)

Query: 609   SGPVEVFITETPSQPNSHPI-----------QWNAPQPS---HISKYILRWRPKNSVGRW 654
             S P E  +   P  P   P+           +W  P+ +    I+ YI+  R   + GRW
Sbjct: 21345 SKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPN-GRW 21403

Query: 655   KEATIPGHL-NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
              +A     L N +T+ GL     YE ++I+    G           +  S P  S+ +T 
Sbjct: 21404 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG---------AISPPSEP--SDAITC 21452

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ---YLDLPS 770
                  +P +       +        ++   +D         E S++G E +    L++  
Sbjct: 21453 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 21512

Query: 771   TATSVNIPDLLPGRKY--IVNVYQISEDGEQSLILSTSQTTAPDAPPDP-TVDQVDDTSI 827
                S N+ +    R+      +   +  G    I +      P  P  P  V +V     
Sbjct: 21513 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKC 21572

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             V+ W  P     A I  Y +    +   + T +        + ++ L  G +Y   + AV
Sbjct: 21573 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 21632

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              +     P+  +      P     P P++ +   +T   + + W  P+S      ++ I 
Sbjct: 21633 NKYGVGEPLESEPVLAVNPYGPPDP-PKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI- 21690

Query: 944   VNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYFKVFAVSHGRESKPL-------TA 991
             V    + GQR +  ++ T  +    V+GL+ G  Y F++ A +    S P          
Sbjct: 21691 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 21750

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYN--VG 1045
                 K   P N + ++ + S++ + W  P     ++ITGY + + L    + +      G
Sbjct: 21751 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG 21810

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
                + Y +  L    EY + + A+        A    T       +PP      +   V+
Sbjct: 21811 LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVV 21870

Query: 1106  T--------------WTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
             T                PAP + +      S   +A  E TS    ++V  +       Y
Sbjct: 21871 TIRACCTLRLFVPIKGRPAPEVKWARDHGESLD-KASIESTSSYTLLIVGNVNRFDSGKY 21929

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRI 1208
              + V      + A +  +V+    PP +L ++    T V T++W+         I  Y +
Sbjct: 21930 ILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV-TLTWDPPLLDGGSKIKNYIV 21988

Query: 1209  TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPIS 1260
                 +  +  +++    H  ++S   D L  G  Y   V    +          ESV  S
Sbjct: 21989 EKRESTRKAYSTVATNCH--KTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 22046

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSIS 1317
             +  +P    P  +   ++  +++ ++W  P       +  ++V      +++     ++ 
Sbjct: 22047 ERPLP----PGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVK 22102

Query: 1318  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              ++    +T L+ G EY   VS+  E+  S P +                 +  N+FTV 
Sbjct: 22103 VTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV- 22159

Query: 1378  WIAPRATITGYRIRHHPEHFSGRP------REDRVP----------HSRNSITLTNLTPG 1421
                    + G  ++     F GRP       +D VP           + N+  LT     
Sbjct: 22160 -------LAGEDLKVDVP-FIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDAC 22211

Query: 1422  TE----YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV---- 1473
              E    YVV +    G     L +            +++   T  S+ +SW  P      
Sbjct: 22212 REDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGS 22271

Query: 1474  TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP-ASSK 1532
             ++  Y +   +T   +  Q  +   +++T     LK G +Y   + A    G S   +S+
Sbjct: 22272 SINNYIVEKRDTS-TTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 22330

Query: 1533  PISINYRTEIDKPSQMQVTDVQD-NSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKT 1587
             P    Y  ++  P    V  +   +S+ V+W        S V GY +    +N     K 
Sbjct: 22331 PTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKL 22390

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL----KFTQV 1643
                   QT+    GL+  VEY   V A+N  G  +P   +       P D     +   V
Sbjct: 22391 NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV 22450

Query: 1644  TPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699
             T  S++ QW  P      ++TGY V      +   MK        +   V+GL+   +YE
Sbjct: 22451 TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYE 22510

Query: 1700  VSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
               V A     + S P++  G +T  + V PPR +      +T +  +  +       F+V
Sbjct: 22511 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES-------FKV 22563

Query: 1757  DAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SSPVVIDASTAI 1813
             DA       P  + IK D        L+   TD+   L ++ D  R  S   ++ A    
Sbjct: 22564 DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSGNYILKAKNVA 22622

Query: 1814  DAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSP 1853
                S   N++ L               T     ++W+PP     + I  YI++  +    
Sbjct: 22623 GERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRL 22682

Query: 1854  PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
                VV           +T L  G EYT  ++A+      EPL
Sbjct: 22683 VWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 22723



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 336/1557 (21%), Positives = 550/1557 (35%), Gaps = 260/1557 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 16298 GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 16352

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 16353 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 16408

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 16409 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 16456

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 16457 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 16514

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 16515 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 16571

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 16572 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 16624

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 16625 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 16683

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 16684 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 16743

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKGNQESP 1076
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G Q  P
Sbjct: 16744 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG-QGKP 16802

Query: 1077  KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT---- 1132
                    T +   + P  + +  +   +       R+G    +     G+   +V+    
Sbjct: 16803 SFCTKPITCKDELAPPTLHLDFRDKLTI-------RVGEAFALTGRYSGKPKPKVSWFKD 16855

Query: 1133  ------SDSGSIVVSGLTPGVEYV---------YTIQVLRDGQERDAPIVNKVVTPLSPP 1177
                    D   I  +  T  +E +         Y + V      R       VV    PP
Sbjct: 16856 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPP 16915

Query: 1178  TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS---LEEVVHADQSSCTF 1234
                          + +SW+     D  G +IT      ++      +     + +++C  
Sbjct: 16916 VGPVSFDEVTKDYMVISWKPPL--DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKV 16973

Query: 1235  DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VPPPTDLRF-TNIGPDTMRVTWA 1288
               L  G +Y   ++       S P+    + A     VP   D    T +  D+  VTW 
Sbjct: 16974 SKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWN 17033

Query: 1289  PPPS--IDLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE- 1343
              P      +TN+++  R +  K    V +  I P     V  +LL G +Y   VS+  E 
Sbjct: 17034 KPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRV-PDLLEGCQYEFRVSAENEI 17092

Query: 1344  -----QHESTPLRGRQKTGLDSP-TGIDFSDITANSFTVHWIAPR----ATITGYRIRHH 1393
                     S P+  +      SP    +  D T NS  + W  PR    + I GY + + 
Sbjct: 17093 GIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQ 17152

Query: 1394  PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGREES-------PLLIGQQ 1444
                     R +  P S       +T L  G  Y   ++A+N   ES       P+L+  +
Sbjct: 17153 KVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDR 17212

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVT--VRYYRITYGETGGNSPVQ---EFTVPGS 1499
                 ++  D  +       +  +    A+   V + ++T+ +   ++P +   + T  GS
Sbjct: 17213 LEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 17272

Query: 1500  KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDN 1556
             K     +  + G  Y++TV       ++PA SK +S+     +DKP     ++V++++ +
Sbjct: 17273 KLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLV-LDKPGPPRDLEVSEIRKD 17324

Query: 1557  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             S  + W        S +T Y V          +        ++    + L    +Y+  V
Sbjct: 17325 SCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFA-KHLNEGNQYLFRV 17383

Query: 1613  YAQNPSGESQPLVQTAVTTIPA---------PTDLKFTQVTPTSLSAQWTPPNVQ----L 1659
              A+N  G   P V+T    I A         P DL    V  T +S  W  P+      +
Sbjct: 17384 AAENQYGRG-PFVETP-KPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPI 17441

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1717
             TGY V     ++ G    I     ++   VV+GL     Y   V A        P   + 
Sbjct: 17442 TGYLVEY---QEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 17498

Query: 1718  VTTLENVSPPRRARVTDATE-------TTI------------TISWRT---KTETITGFQ 1755
             +   E + PP         E       TT+            T  W T   + +T   + 
Sbjct: 17499 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 17558

Query: 1756  VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1815
             V+    +    I+  ++ D   Y IT                 NA  S  V    T +D 
Sbjct: 17559 VETDNFSSVLTIKNCLRRDTGEYQITV---------------SNAAGSKTVAVHLTVLDV 17603

Query: 1816  PSN----LRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
             P      +  L  TP  + +SWQPP+    + +  YI++ +        VV       T+
Sbjct: 17604 PGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV-SSGSSKTK 17662

Query: 1868  ATITGLEPGTEYTIYV-----IALKNNQKSEPLIGRKK------TGQEALSQ-----TTI 1911
               I  L+ G EY   V     I +     S P + + K       G+  ++       T+
Sbjct: 17663 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 17722

Query: 1912  SWA-PFQDTSEYIISCHPVGTDEEPLQFRV---PGTSTSATLTGLTRGATYNIIVEA 1964
             SW  P  D    I   +    +      RV   P       +TGL  G TY   V A
Sbjct: 17723 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFA 17779



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 25278 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 25335

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 25336 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 25386

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 25387 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 25443

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 25444 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 25500

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 25501 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 25560

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 25561 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 25614

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 25615 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 25673

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 25674 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 25731

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 25732 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 25782

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 25783 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 25839

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 25840 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 25898

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 25899 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 25956

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 25957 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 26016

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 26017 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 26075

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 26076 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 26133

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 26134 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 26189

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 26245

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 26246 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 26300

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 26301 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 26359

Query: 1621  SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
               P        +T  P+P + L  T ++  S+S  W  P      ++  Y V    K + 
Sbjct: 26360 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 26419

Query: 1673  GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
               +K       S+  VVSGL   ++Y   V+A      S P + ++  L  E + PP   
Sbjct: 26420 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 26477

Query: 1729  ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
                        R     +  I IS +              +    F  +    N    ++
Sbjct: 26478 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 26537

Query: 1769  RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
              ++  D   Y IT        K ++         + VV+D       P  +  +  T  S
Sbjct: 26538 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 26586

Query: 1829  LLVSWQPPR----ARITGYII 1845
             + + W+PP+    +++T YI+
Sbjct: 26587 VTLKWEPPKYDGGSQVTNYIL 26607



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 316/1532 (20%), Positives = 551/1532 (35%), Gaps = 236/1532 (15%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 28537 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 28595

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 28596 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 28651

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 28652 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 28703

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 28704 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 28761

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 28762 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 28821

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 28822 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 28875

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 28876 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 28934

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 28935 AQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 28992

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 28993 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 29048

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 29049 DARLHGDLVTIRAGSDLV--------LDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 29100

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 29101 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 29159

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS---SCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+   +    S     L    EY   V  V
Sbjct: 29160 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 29217

Query: 1251  KDDKESVPISDTIIPA-----VPPPTDL-RFTNIGPDTMRVTWAPPPSI---DLTNFLV- 1300
                   VP+    I A     +P P  +      G + + + W  P S    +++N+LV 
Sbjct: 29218 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 29277

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 29278 KREKKSLRWTRVNKDYVVY-------DTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 29330

Query: 1354  QKTGLDSPTGID-------FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                    P+            D T +S ++ W  P       I GY +    +      R
Sbjct: 29331 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 29390

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 29391 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 29449

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 29450 DDLKKTVTIRAGASL------RLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 29502

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 29503 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 29561

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 29562 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 29620

Query: 1622  QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
             +P   +    V+ +P  P  L+   VT ++++  W  P      +LTGY +         
Sbjct: 29621 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 29680

Query: 1674  PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
              MK + L P      V+ L    +Y        E  V   ++T+T+   Q   V+ T++ 
Sbjct: 29681 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 29740

Query: 1724  VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
              + P++     A    E  I I+ R        F    +  + +  ++   K    +   
Sbjct: 29741 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 29800

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
             T ++   +Y + L  +      +  VI           ++       S+ +SW+PP    
Sbjct: 29801 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 29860

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA-----LKNN 1889
              A ++GY+++      P    V      VT +T   T L  G EY   V A     + + 
Sbjct: 29861 GAPLSGYVVEQRDAHRPGWLPVSE---SVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 29917

Query: 1890  QKSEPLIGRKKTGQEALSQT-----------TISWAPFQD-----TSEYIISCHPVGTDE 1933
              +SE +  R         +T           T++W P +D      + YI+    V  D 
Sbjct: 29918 LQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 29977

Query: 1934  EPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                  +VP T T    TGLT G  Y   V A+
Sbjct: 29978 WVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAI 30009



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
             T  +VT L  G  Y F+V  V+     +PL +     LD       PT+L+  + T  ++
Sbjct: 25940 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 25999

Query: 1014  LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
              + W+ P +    +I+GY +     RR +     V   V+K P+ +L+  S         
Sbjct: 26000 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 26053

Query: 1061  EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
             EY V      G    ++ SP          P     P   +  +TTI I W        A
Sbjct: 26054 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 26113

Query: 1111  PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
             P  G+ +  + S   +    + S  G+   +SGLT G EYV+ ++ +      D  +   
Sbjct: 26114 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 26173

Query: 1165  PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
             P + K      P  ++  E      V       +TV +     P++    + + P    +
Sbjct: 26174 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 26228

Query: 1218  GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
               +  +   + ++S T +N +     +Y +++  V     S+ +   ++    PPT++  
Sbjct: 26229 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 26286

Query: 1276  TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
              ++  ++  ++W  P +          +PVKN      E   +  +S ++N    +  +T
Sbjct: 26287 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 26339

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
             NL  G  Y   VS   E     P   ++   +      P  +  + I+ +S ++ W+ P 
Sbjct: 26340 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 26399

Query: 1383  ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
                 G RI H+      + +++ V  +    T   ++ L   +EY   + A N    S  
Sbjct: 26400 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 26458

Query: 1438  -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
                  P+LI +Q    ++     P     V A      +  D P       ++T    G 
Sbjct: 26459 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 26515

Query: 1488  N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                    F    +    TI+ LK  V      Y +T    S  +   I+I     +D+P 
Sbjct: 26516 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 26571

Query: 1547  Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
                  + ++D+ + S+++KW P      S VT Y +     +    T+  +A   +T M 
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 26630

Query: 1599  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
             +  L    EY   + A+N  G S  +    VT     T P P    + T VT  S++  W
Sbjct: 26631 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 26690

Query: 1653  TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
               P       + GY + +  +      K   L   ++   V+ +     YE  VYA    
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 26750

Query: 1709  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
                +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V+   +P
Sbjct: 26751 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 26810

Query: 1761  ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
                 T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T ID+
Sbjct: 26811 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 26866



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)

Query: 730   EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
             +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 13498 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 13556

Query: 786   YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
             Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 13557 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 13616

Query: 836   APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
             + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 13617 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 13676

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
             +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 13677 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 13736

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
                + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 13737 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 13795

Query: 1009  TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
             T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 13796 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 13855

Query: 1065  SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
              + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 13856 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 13915

Query: 1114  GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
             G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 13916 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 13974

Query: 1168  NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
               +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 13975 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 14031

Query: 1226  HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
                +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 14032 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 14091

Query: 1275  FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
               NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 14092 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 14150

Query: 1332  TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
             + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 14210

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                 I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 14211 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 14270

Query: 1437  SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
              P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 14271 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 14318

Query: 1494  FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
             + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 14319 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 14374

Query: 1537  NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
             +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 14375 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14434

Query: 1597  MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
             M  + +   +E   SV A         +N  G +   +   V  +P P  D+K + +T +
Sbjct: 14435 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 14494

Query: 1647  SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
             S    W PP     T     V  + + G    I +    +  S  V  L+   +Y   V 
Sbjct: 14495 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 14554

Query: 1704  ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
             A+     ++   G    L+N            PP    V + T   +TI+W+        
Sbjct: 14555 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 14609

Query: 1750  TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
              I G+ ++ + A G+   +R  +    + +YT  GL+ G +Y+  +       +++ +R+
Sbjct: 14610 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 14668

Query: 1803  SPVVIDASTAIDAP 1816
             +P    A   IDAP
Sbjct: 14669 TPPT-KAVDPIDAP 14681



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 272/1303 (20%), Positives = 467/1303 (35%), Gaps = 174/1303 (13%)

Query: 773   TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  +  LL G +YI     VN Y + E  E   I +    T P  P    +  V   S+
Sbjct: 25940 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 25999

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
              + WSRP++     I+GY I            +N  P     V  + L+ G +Y   +YA
Sbjct: 26000 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 26059

Query: 883   VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
                 + +  + +  ET+   R++    +PSP    + V+     +TI W  P     + +
Sbjct: 26060 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 26115

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
             TGY V+    +   +    +   R T   ++GL+ G  Y F+V +V+    S P  +   
Sbjct: 26116 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 26174

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
             Q   + +        +E   T++V+         G   T+ +  RG+P            
Sbjct: 26175 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 26226

Query: 1040  ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                R Y V  + S+  L     N   + +YT+++  +           V  T  P ++I 
Sbjct: 26227 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 26285

Query: 1093  PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
                 +VT+ + V++W        AP   + +  R +   +A   VT++    S  V+ L 
Sbjct: 26286 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 26342

Query: 1145  PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
              G  Y + +    +   G   +     K+    SPP  L + +     V +++W   E  
Sbjct: 26343 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 26401

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                 I  Y +        Q N ++  V A  +      L    EY   V+       S P
Sbjct: 26402 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 26458

Query: 1259  ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
               + ++P +      PP  D++  N    T+ V       +D+         V    D  
Sbjct: 26459 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 26515

Query: 1313  ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
              L  +   N  +   NL    +  V+  +   +  +    G  K  ++         PTG
Sbjct: 26516 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 26575

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              +  SDIT  S T+ W  P+    + +T Y +    E  +    E     +R  + +  L
Sbjct: 26576 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 26634

Query: 1419  TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             T G EY   I A N        + + + +    T    P    V   T  S+ + W  P 
Sbjct: 26635 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 26694

Query: 1473  VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
                   V  Y +   +       +   +    +   ++ +  G+ Y   VYA    G   
Sbjct: 26695 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 26754

Query: 1529  ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
              S     +      + P  +++TD+  NS+S+ W        S +TGY V          
Sbjct: 26755 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 26814

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ----TAVTTIPAPT--- 1636
             TK       +T+  I GL    +Y   V+A+N  G  S P       T + +   P    
Sbjct: 26815 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 26874

Query: 1637  DLKFTQV------TPTSLSAQWT-PPNVQLTGYRVRVTPKE-KTGPMKEINLAPDSSSVV 1688
              L++T+V      T   L A  +  P   +  Y+     KE +T  +  +    D +S++
Sbjct: 26875 PLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYK---DDKELQTNALVCVENTTDLASIL 26931

Query: 1689  VSGLMVATKYEVSVYALK--DTLTSRPAQGVVTTLENVSPPRRA-RVTDATETTITISWR 1745
             +     A +     Y LK  + + S  A   V  L+   PP         T   IT+ WR
Sbjct: 26932 IKD---ADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWR 26988

Query: 1746  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
                +     IT + V+    +       +   +    T T +  G +Y   +  +N    
Sbjct: 26989 PPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 27048

Query: 1802  SSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPG 1851
               P+  D+  A +A      P        T NS+ V W  P A     I+GY ++     
Sbjct: 27049 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 27108

Query: 1852  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTI 1911
             S     V +     T   +TGL   ++Y   V A+               GQ        
Sbjct: 27109 SLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVN------------AAGQ-------- 27148

Query: 1912  SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 1954
                PF + SE+  +  P+     P + R+  ++ S+   G ++
Sbjct: 27149 --GPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSK 27189



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 18700 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 18757

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 18758 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 18805

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 18806 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 18865

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 18866 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 18925

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 18926 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 18985

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 18986 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 19037

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 19038 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 19097

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 19098 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 19155

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 19156 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 19213

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 19214 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 19271

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 19272 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 19331

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 19332 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 19376

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 19377 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 19434

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 19435 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 19494

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 19495 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 19554

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 19555 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 19609

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 19610 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 19668

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 19669 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 19725

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 19726 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 19783

Query: 1630  TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
                P  P ++   +++  S    W PP +     +  Y V+    E+      +      
Sbjct: 19784 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 19842

Query: 1685  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
             +S  V+ L     Y   V+A  +     P +    V   +   P    +V   ++++ +I
Sbjct: 19843 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 19902

Query: 1743  SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
              W+         I G+ VD +    +   QR +K     Y+   L  G +Y   +   N+
Sbjct: 19903 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 19960

Query: 1799  NARSSP--VVIDASTAIDAP 1816
             N   +P  + + A   + AP
Sbjct: 19961 NGEGTPSEITVVARDDVVAP 19980



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 271/1284 (21%), Positives = 458/1284 (35%), Gaps = 188/1284 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 27420 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 27479

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 27480 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 27538

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 27539 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 27593

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 27594 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 27651

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 27652 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 27711

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 27712 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 27771

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 27772 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 27831

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 27832 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 27889

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 27890 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 27945 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 27999

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 28000 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 28056

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 28057 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 28114

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 28115 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 28174

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 28175 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 28222

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++    P+ ++VTD    ++S++W        
Sbjct: 28223 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 28282

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 28283 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 28342

Query: 1627  T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
             T    AV  + AP    D  F Q       A     +++L   Y+ R TP    + P   
Sbjct: 28343 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 28397

Query: 1678  INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
             ++L  D  ++   S L V       A KY ++V   ++   S+     V  L+   PP  
Sbjct: 28398 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 28454

Query: 1730  ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
                 D T  + T+ W          I  + V+   A+ ++    + K   + + +  L  
Sbjct: 28455 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 28514

Query: 1786  GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
             G  Y   +  +N+         P  I A+     P  L  + T+ +S +++W  P     
Sbjct: 28515 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 28574

Query: 1838  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
             +RITGY+++  + GS     V          T+  L   TEY   V A  +   SEP   
Sbjct: 28575 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP--- 28629

Query: 1898  RKKTGQEALSQTTISWAPFQDTSE 1921
                  +EA S   I     + T++
Sbjct: 28630 -----REAFSSVIIKEPQIEPTAD 28648



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)

Query: 710   TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
             TV+   TP  P+    E   +I  +S +  W    D      + Y L ++     + +++
Sbjct: 14795 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 14851

Query: 767   DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
              + ST      ++  L+ G++Y+  V   +  G         +++      PDAP  P V
Sbjct: 14852 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 14911

Query: 820   DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
             + V   S++V+W+ P+   +PI GY   +    E +ST  +    +    L     G+  
Sbjct: 14912 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 14968

Query: 877   NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
              +T ++ V     + P      +      D +  P P   +  + +   + + W PP   
Sbjct: 14969 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 15028

Query: 932   --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
                 + GY VD  ++  N      +++  + + T  E+     G  Y  +V AV+   E 
Sbjct: 15029 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 15085

Query: 987   KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
              P   Q  T          +LD             T+ +             WT    ++
Sbjct: 15086 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 15145

Query: 1025  TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
                R+ +           NVG     + K  LR  +    Y ++     G++ +     V
Sbjct: 15146 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 15193

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
             F    P   + P  T       ++ W+       +   GF +  + ++     + + ++ 
Sbjct: 15194 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 15251

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
                 ++GL  G EY +  +V+   +    P V       V PL PPT+     + E    
Sbjct: 15252 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 15309

Query: 1188  TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
             T  +T+ W+   +     I GY I     +      + + +    +S   +NL     Y 
Sbjct: 15310 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 15366

Query: 1245  VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
               V  V +  ES   +P++  I     PPT     ++  DT++V    P  I  D+T   
Sbjct: 15367 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 15426

Query: 1300  VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
             +        E V E    P+D   +    +  +E    +S   +V E   +  +    + 
Sbjct: 15427 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 15483

Query: 1357  GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
             G                P  +  +DI A S  + W AP     G  I H+   +  + R 
Sbjct: 15484 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 15542

Query: 1402  REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
             + +    +  ++     +  L P  +Y   + A+N    S      +  + D       P
Sbjct: 15543 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 15602

Query: 1452  RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
                +V+A T  S+L+SW  P       +  Y +   E G         +P+ +  + G +
Sbjct: 15603 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 15662

Query: 1501  STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
                 +  L  GV Y     A+   G  P S  S P ++ +       PS  +V D   +S
Sbjct: 15663 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 15720

Query: 1558  ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
             IS+ W P +    SP+ GY V    +   G T  K    PD+   T E + P ++    Y
Sbjct: 15721 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 15777

Query: 1609  VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
                V A N +GES+P   T    IPA TD++        + AQ     V   G ++R+  
Sbjct: 15778 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 15832

Query: 1667  ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
                   TPK   E  G  K              ++  A +SS +++     +   + S+ 
Sbjct: 15833 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 15892

Query: 1704  ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
             A K+    + A   V  ++   PP+  +V+D T  +  +SW+   +     I G+ ++  
Sbjct: 15893 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 15951

Query: 1760  PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
               +G+   +  + PD  S T  +  L     Y   +   N      PV  I  +TA D  
Sbjct: 15952 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 16009

Query: 1816  -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
                  P  L+    T N++ +SW+PP+    + +T YI++   ++  G+         + 
Sbjct: 16010 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 16069

Query: 1864  GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
              V E   T+  L  G EY   V A+     S+P
Sbjct: 16070 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 16102



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1521 (20%), Positives = 534/1521 (35%), Gaps = 198/1521 (13%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+      P++       P ++ + +     NS  + W  P+    S I +YI+  +
Sbjct: 23113 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 23170

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K+S  +W E      L +  I  L  G  Y  +++++ + G  +         S + P+
Sbjct: 23171 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 23221

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E        + S  V +       +S      T++  +    L +        
Sbjct: 23222 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 23280

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
              L  T  S+       G +Y + V  +   G+++  +       PD P  P   D V   
Sbjct: 23281 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 23338

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
             SI + W+ P       IT Y +    +       ++      ++ ++ L+ G +Y   I+
Sbjct: 23339 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 23398

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
             A  EN+      ++ +          P P    F   ++   + I W  P     S V G
Sbjct: 23399 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 23456

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
             Y ++    N          I  +T  +   L  G+ Y F+V+A   V  G+ SK      
Sbjct: 23457 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 23516

Query: 994   TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
                  D P   + +    + + ++WT P     + ITGY +       G+  + +    +
Sbjct: 23517 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 23576

Query: 1049  -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
              +++ +  L     Y   ++A    G    P  +TG  T       P  S+ P   +  +
Sbjct: 23577 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 23633

Query: 1101  TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             T +V           +   P P I +  G +   +      + T     ++V        
Sbjct: 23634 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 23693

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
               Y ++       +  P+  KV+    PP          +   +++W    +    DI+ 
Sbjct: 23694 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 23753

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
             Y +    T+      +   V  +    T   L  G EY      V+ Y V +  ES P+ 
Sbjct: 23754 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 23811

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
               +  ++P   PP  L  TNI  D+M V W  P S   +  +      ++   +  +  +
Sbjct: 23812 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 23869

Query: 1318  P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
                 +D  + +T L    EY   VS  +     E +P     K          PT     
Sbjct: 23870 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 23929

Query: 1368  DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
             D T NS T+ W  P     + I GY +    E       E ++   +  + +T      L
Sbjct: 23930 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 23985

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
             T   EY + + ALN      + +G+ ++V    +  + + A P   L S     + VR  
Sbjct: 23986 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 24039

Query: 1477  -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
                RI     G  +P   ++    + T  +  ++ GV+YT              Y +   
Sbjct: 24040 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 24098

Query: 1525  GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
               S + S  +++        P  + V +V+ +S  + W P      + V  Y +      
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 24158

Query: 1581  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
                     ++   +T   +E L     Y   V A+N  G   P+     V+ A    P P
Sbjct: 24159 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 24216

Query: 1636  TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
               +  T V+ TS S  W  P      ++ GY V + PK  EK   + E  +     + VV
Sbjct: 24217 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 24272

Query: 1690  SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
             +GL    +Y+  V A  +   S P   GV      +T   ++  P       A E     
Sbjct: 24273 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 24332

Query: 1738  ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
                       ISW    E +   T   V+    +    I+   K D   YT+T       
Sbjct: 24333 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 24391

Query: 1789  YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
                   T  +N   S +V++       P  +RF   + + +++SW+PP      +I+ YI
Sbjct: 24392 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 24441

Query: 1845  IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR------ 1898
             ++     +    +V       T   IT L+ GTEY   + A     KS PL  +      
Sbjct: 24442 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQY 24500

Query: 1899  --KKTGQE--------ALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQF----RVPGT 1943
               K+ G          +  Q  + W  P  D    II  H    ++  + +    + P  
Sbjct: 24501 PFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 24560

Query: 1944  STSATLTGLTRGATYNIIVEA 1964
              T    TGL  G  Y   V A
Sbjct: 24561 DTKFKTTGLDEGLEYEFKVSA 24581



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 26568 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 26627

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 26628 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 26685

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 26686 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 26744

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 26745 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 26803

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 26804 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 26860

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 26861 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 26920

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 26921 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 26980

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 26981 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 27037

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 27038 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 27097

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 27098 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 27157

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 27158 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 27213

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 27214 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 27273

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 27274 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 27329

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 27330 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 27384

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 27385 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 27442

Query: 1616  NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
             N  G  +P   T       +PAP  DL     T TS+   WT P+      +T Y V   
Sbjct: 27443 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 27502

Query: 1668  PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
              K E+T     I+    +  + VS L   +  E  V+A  +   S P   G +T  E + 
Sbjct: 27503 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 27559

Query: 1726  PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
              P          +  V       + + ++ K +    +  D +P      ++  +T    
Sbjct: 27560 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 27619

Query: 1775  VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
               S      + G  Y + L    DNA     V      +  PS     +RF     +S++
Sbjct: 27620 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 27675

Query: 1831  VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
             +SW  P       IT Y I+  +      ++V       T   +  L    EY   V A 
Sbjct: 27676 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 27734

Query: 1887  KNNQKSEPLI 1896
                  S+PL+
Sbjct: 27735 NRYGVSQPLV 27744



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1485 (20%), Positives = 517/1485 (34%), Gaps = 213/1485 (14%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
             S+ + T +S ++SW            EY +  +G   Q       + +  I ++   ++ 
Sbjct: 27470 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 27528

Query: 787   IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
              V  +++    E+ L   ++    T  +    P VD  D     + VR          Y+
Sbjct: 27529 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 27588

Query: 843   IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
                 PS+      L L E        T N +TLS      ++      + +N      V 
Sbjct: 27589 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 27648

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
             I   T G P     P    ++F E+    V + W  PE      +T Y ++    +    
Sbjct: 27649 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 27704

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
                   ++R TF +V  L     Y F+V A +    S+PL      A+   ++  P    
Sbjct: 27705 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 27763

Query: 1005  FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
              + N T   + + W  P     +++TG+ +          ++ N  P S  +Y    L  
Sbjct: 27764 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 27823

Query: 1059  ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
               +Y   + A       SP     FT        P  P   +VT  TI + W P  R G 
Sbjct: 27824 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 27883

Query: 1116  K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                    +   QG E  R V  +   +      V+GL+PG  Y + I            I
Sbjct: 27884 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 27929

Query: 1167  VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
                 V  +SPP+                +E  P+   G++  S E      +   R    
Sbjct: 27930 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 27989

Query: 1212  PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
              T  + G  +E+ ++    D    T   +      +  VYTV+    S        V + 
Sbjct: 27990 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
             DT    V P   +RFTNI  + M + W  P +     +T++++             ED  
Sbjct: 28050 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 28106

Query: 1313  ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
             E   + S  A+ L N   G EY   VS+V +     PL         Q T  D+P   + 
Sbjct: 28107 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 28160

Query: 1367  SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
             S+IT NS T+ W  P     + I  Y +    +  +   +   + P S     +T LT G
Sbjct: 28161 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 28220

Query: 1422  TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
              EY   ++A N     P      LI  +  V+    P  ++V   + T++ + W  P   
Sbjct: 28221 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 28280

Query: 1475  VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
                  I Y      + + ++    +    K+  T++ L+ G +Y   V A+   G+GDS 
Sbjct: 28281 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 28340

Query: 1528  --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
                 + K +      E+D  +  + T V     S++ ++      T   V + P +    
Sbjct: 28341 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 28400

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
                       + +T+E          ++  +N SG         V   P P   + F  V
Sbjct: 28401 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 28460

Query: 1644  TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
             T  S +  W  P +   G R+     EK    +     I+         V+ L     Y 
Sbjct: 28461 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 28519

Query: 1700  VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
               V A+ +     P +    +   E  +PPRR  V D ++++  ++W          ITG
Sbjct: 28520 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 28579

Query: 1754  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
             + ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S  I
Sbjct: 28580 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 28638

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT---- 1866
               P         P + L         IT  +I   K GSP    VP   RP P VT    
Sbjct: 28639 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVTWKLE 28684

Query: 1867  --------EATITGLEPGTEYTI----------YVIALKNNQ-------------KSEPL 1895
                       +IT  +  T  T+          Y + L+N               +  P+
Sbjct: 28685 EMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPV 28744

Query: 1896  IGRKKTGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 1950
              G  +    +     +SW   +D      + YI+     GT    L        T   +T
Sbjct: 28745 TGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL-VNSSVKRTQIKVT 28803

Query: 1951  GLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE 2010
              LT+   Y+  V +   + R  V + + +           P+  +  + Y VS  A+   
Sbjct: 28804 HLTKYMEYSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 28860

Query: 2011  WERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGV-----NYKI 2050
             WE     G     + +G+       ++  W  +N V     NYK+
Sbjct: 28861 WEEPYHDGGS---KIIGYWVEKKERNTILWVKENKVPCLECNYKV 28902



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 272/1331 (20%), Positives = 495/1331 (37%), Gaps = 207/1331 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 15215 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 15272

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 15273 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 15319

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 15320 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 15379

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 15380 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 15435

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 15436 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 15496 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 15552

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 15553 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 15612

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 15613 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 15668

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 15669 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 15728

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 15729 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 15784

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 15785 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 15844

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 15845 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 15903

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 15904 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 15962

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 15963 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 16022

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 16023 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 16082

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 16083 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 16142

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 16143 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 16202

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 16203 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 16259

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T     +
Sbjct: 16260 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315

Query: 1632  IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
             +P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N  P  +
Sbjct: 16316 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 16373

Query: 1686  -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
                  S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP     +V
Sbjct: 16374 MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 16429

Query: 1733  TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
             TD T+++  + W    +     +TG+ V+     G+   ++    +VR     +TGL+ G
Sbjct: 16430 TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 16488

Query: 1787  TDYKIYLYTLN 1797
               YK  +  +N
Sbjct: 16489 AFYKFRVRAVN 16499



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)

Query: 609   SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
             S P E+   E P+ P S P+  +        K+I + W+P  KN     +G   E    G
Sbjct: 14270 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 14327

Query: 662   -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
                   +NS  IK LK     GVV + + +    ++   G  E +       +   P   
Sbjct: 14328 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 14386

Query: 709   NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
              T+  ET     +     S+  +   +  V  VS        +    L+ + D       
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 14439

Query: 769   PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
                +  + +P  +     I  +   ++ G  +  ++      P    D     +  +S  
Sbjct: 14440 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 14497

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
             + W  P+     PI  Y +    +   +   +   E   S T+ DL P  +Y   + AV 
Sbjct: 14498 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 14557

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
             +      + ++              P D++    T   +TI W PP     S + GY ++
Sbjct: 14558 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 14617

Query: 941   VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
              I     GE   +      +PI   T     GL  G  Y F+V A +    S+P  A   
Sbjct: 14618 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 14671

Query: 995   TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
             TK    +DAP     T+L+ V   D   L           + W      I    +     
Sbjct: 14672 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 14730

Query: 1032  GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
              L RR     Q  +  V P   +  + N +                  Y + +    G  
Sbjct: 14731 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 14790

Query: 1074  ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
             ++P    V  T  PG  I     ++ +T+++  W P    G    +  +   E   +   
Sbjct: 14791 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 14846

Query: 1134  DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
             DS  IVV+            L  G EY++ ++   +      P V+K +    P  PP  
Sbjct: 14847 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 14905

Query: 1179  -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
              +  +  +  +  + V W   +     I GY +     N    + + + +  +      D
Sbjct: 14906 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 14964

Query: 1236  NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
              L  GL Y   V         +  P SD      P  PP P   R T+    T+ + W P
Sbjct: 14965 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 15024

Query: 1290  PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
             P      ++  + V    V   E               +  +  G +Y + VS+V    E
Sbjct: 15025 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 15084

Query: 1347  STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
               P   +  T  +   P  ++          +        + G  +R  P   +GRP   
Sbjct: 15085 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 15135

Query: 1405  RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
             +V         ++ + + N+   +E ++            I A N           +  V
Sbjct: 15136 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 15193

Query: 1448  SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
              DVP    DL+ V       L++W  P            E  G S +  F +        
Sbjct: 15194 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 15241

Query: 1500  ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
                      +S   I+GL  G +Y   V A    G  P    P+ I     +D       
Sbjct: 15242 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 15297

Query: 1545  PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
             P ++  T+   ++I++ W        SP+ GY +     + P   +        T   +E
Sbjct: 15298 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 15357

Query: 1601  GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
              L     Y   V A N  GES+P       ++P    ++  +V PT    LS +     V
Sbjct: 15358 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 15410

Query: 1658  QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
             +  G  V + P + TG PM +I  + + + +   +  +  TK EVS             V
Sbjct: 15411 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468

Query: 1703  YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
                K T T   +  + +   NV        SPPR   VTD    +  ++W    +     
Sbjct: 15469 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 15528

Query: 1751  ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
             IT + +D   A+ +      +      + Y I  L P   Y+  +     Y ++D  +S 
Sbjct: 15529 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 15588

Query: 1804  PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
              VVI D       P   + LA T  S+LVSW PP     + ITGY ++  + GSP    V
Sbjct: 15589 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 15648

Query: 1859  PRPRPGVTEATITGLE 1874
                R  +T+  + G+E
Sbjct: 15649 --SRAPITKVGLKGVE 15662



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 171/752 (22%), Positives = 283/752 (37%), Gaps = 116/752 (15%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 16077 TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 16136

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 16137 VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 16190

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 16191 TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 16248

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 16249 ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 16301

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 16302 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 16361

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 16362 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 16418

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 16419 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 16478

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
             ++ + GL+    Y   V A N +G  +P   T V       ++K   V+P   L A    
Sbjct: 16479 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 16532

Query: 1655  PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
               V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   V
Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 16592

Query: 1703  YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
             Y+L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + 
Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 16652

Query: 1756  VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
             ++   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+
Sbjct: 16653 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 16710

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
              +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V    
Sbjct: 16711 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 16770

Query: 1863  PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 + T+ GL+ G  Y   V A+    + +P
Sbjct: 16771 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 16802



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 258/1144 (22%), Positives = 397/1144 (34%), Gaps = 207/1144 (18%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
             P P ++L+   VT    TI W  P     S +T +   ++    P + G  +  S  T  
Sbjct: 18002 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNF---IVEYRKPNQKGWSIVASDVTKR 18058

Query: 963   EV-TGLSPGVTYYFKVFA-----VSHGRESKP--LTAQQTTKLDAPTNLQFVNETDSTVL 1014
              +   L     YYF+V A     V    E+K   L      +   P NL   ++  + V 
Sbjct: 18059 LIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVY 18118

Query: 1015  VRWTPPRAQITGYRLTVGLTRR------------GQPRQ--YNVGPSVS------KYPLR 1054
             ++W  P        L+  + RR            G  ++  Y V   V       +   +
Sbjct: 18119 LKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTK 18178

Query: 1055  NLQPASEYT-VSLVAIKGNQESP----KATGVFTT-------LQPGSSIPPY-NTEVTET 1101
             N    S++     V +K + + P    K +GV T        L+ G    P+     T+ 
Sbjct: 18179 NEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD 18238

Query: 1102  TIVITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVY--TIQVLRD 1158
                   T +PR+  K+  R  S      +   SD G  VV+       +V   T+ VL  
Sbjct: 18239 KDATDLTRSPRV--KIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL-- 18294

Query: 1159  GQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVS---WERSTTPDI--TGYRIT--- 1209
               ++  P+ N K+V   S    +  +   D G   +     E+  T  +  + Y  T   
Sbjct: 18295 --DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLT 18352

Query: 1210  --TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
               TT T   +GN     V A+    T     P  E    +   K DK          P  
Sbjct: 18353 PGTTVTRLIEGNEYIFRVRAENKIGT----GPPTESKPVIAKTKYDK----------PGR 18398

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVV 1324
             P P ++  T +  + M V W PP      +    +   K +     + ++ S   +  + 
Sbjct: 18399 PDPPEV--TKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMK 18456

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDS------PTGIDFSDITANSFTVH 1377
             + NLLP  EY   V +  E     P L  R     D       PT     D T +S T+ 
Sbjct: 18457 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 18516

Query: 1378  WIAP----RATITGYRIRHHPEHFSGRPRED------RVPHSRNSITLTNLTPGTEYVVS 1427
             W  P     A I GY +   P+     P E            R   T+T+L    EY   
Sbjct: 18517 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 18576

Query: 1428  IVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
             + A N      + IG+ + + +  +  E++      L  S     V VR           
Sbjct: 18577 VCAQN-----QVGIGRPAELKEAIKPKEILEPPEIDLDASM-RKLVIVR----------A 18620

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTIT-------------VYAVTGRGDS------- 1527
               P++ F +   +    ++  K G+D  +              V   + R DS       
Sbjct: 18621 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 18680

Query: 1528  --PASSKPISINYRTEIDKP---SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
               PA  K + +N R  +D P   S ++V+DV   S  V W P      S VT Y V    
Sbjct: 18681 VNPAGEKAVFVNVRV-LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKRE 18739

Query: 1579  KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTT 1631
              +      T T    +T   +  L P  EY   V A N  G   P       L    ++ 
Sbjct: 18740 ADRK-TWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE 18798

Query: 1632  IPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
                P  L+ T++T  S +  W PP        +  +T YR    P ++     E ++  D
Sbjct: 18799 PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKD 18855

Query: 1684  SSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----- 1736
              S +VV+GL    KY+  V A      S P  A+GV    E + PP+       T     
Sbjct: 18856 LS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGK 18914

Query: 1737  ----------ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGL 1783
                       +   T  W+  + E +T   +    A+  +   I+   + D   Y++T  
Sbjct: 18915 KLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAE 18974

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----AR 1839
                           D  +   VV+DA      P ++  +     SL  SW  P     + 
Sbjct: 18975 NSSG---------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSN 19023

Query: 1840  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1899
             IT YI++ +   S    V        T   +  L PG EY   V A      SEPL   K
Sbjct: 19024 ITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPK 19082

Query: 1900  KTGQ 1903
                Q
Sbjct: 19083 MVAQ 19086



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 117/534 (21%), Positives = 206/534 (38%), Gaps = 63/534 (11%)

Query: 1414  TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
             T+T L  G  EY+  + A N          ++P+    +  V   P ++ +       + 
Sbjct: 13149 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 13208

Query: 1466  ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             ++W+ P       +  Y I   +          TV     +AT++ +  G +Y+  V A 
Sbjct: 13209 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 13268

Query: 1522  TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
                G    S+    +     I++PS    +  +D   +S+ +KW P      SP+ GY +
Sbjct: 13269 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 13328

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
                 +      +       +    + GL+   +Y+  V A+N +G S P      + I  
Sbjct: 13329 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 13382

Query: 1635  PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
             P       V PT  LSA     +   PN     V  TGY R   T        +TG   +
Sbjct: 13383 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 13442

Query: 1678  INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
             +      + +V+S    + + +  +Y LK     +   G   V  +   S P+  +  D 
Sbjct: 13443 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 13499

Query: 1736  TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
             T+ ++ ++W    +     +TG+ V+    + +T  +         +T+  L  G +Y  
Sbjct: 13500 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 13559

Query: 1792  YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
              +   N      P  +D        +T  D P N+++   T NS+ ++W PP+    +RI
Sbjct: 13560 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 13619

Query: 1841  TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
              GYI++    GS        P    T+  +TGLE G  Y   V AL     S+P
Sbjct: 13620 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP 13672



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)

Query: 806   SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
             S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 13186 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 13245

Query: 861   TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
                S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 13246 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 13300

Query: 916   VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
              + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 13301 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 13360

Query: 972   TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
              Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 13361 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 13420

Query: 1020  -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
              PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 13421 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 13476

Query: 1079  TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
             +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 13477 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 13531

Query: 1130  EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
             +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 13532 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 13591

Query: 1178  TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
              N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 13592 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 13649

Query: 1235  DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
               L  G  Y   V  +     S P   T  I AV                          
Sbjct: 13650 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 13708

Query: 1272  DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
             +L  T  G    ++TW     I   +  +    V  +  V  +    SD          G
Sbjct: 13709 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 13759

Query: 1332  TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
             T  + +V+          +    K G   P   D +D+T  S  + W  PR    + IT 
Sbjct: 13760 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 13817

Query: 1388  YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
             Y +         R  +  V H  +S         T L P  EY+  + A N        +
Sbjct: 13818 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 13870

Query: 1436  ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
              SP+    Q      P  LE    T  ++ ++W  P       +  Y +   +   +  V
Sbjct: 13871 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 13930

Query: 1492  QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
             +   +P   +T  + GL     Y   V A  + G G    S++PI I  +  ID P    
Sbjct: 13931 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 13988

Query: 1547  QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
             +  V DV   S+ + W        + +  Y V    K G         G   T+  + GL
Sbjct: 13989 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 14047

Query: 1603  QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
                 EY   V A N +GES+P       L +  +     P  L+   +T  +   +WT P
Sbjct: 14048 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 14107

Query: 1656  NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
                    +T Y V      + G  + ++     +   V+ L      E S+Y  +    +
Sbjct: 14108 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 14161

Query: 1712  RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
                Q   T +E+            PP    V D T+  + + W          I  + ++
Sbjct: 14162 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 14221

Query: 1758  AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
                  G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P        + D
Sbjct: 14222 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 14280

Query: 1809  ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
              ++    P +L         + ++W+PP     + I GY ++    G+     V  RP  
Sbjct: 14281 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 14340

Query: 1864  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
              +      G+ P  EY + V A+     SEP
Sbjct: 14341 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 14371



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 265/1308 (20%), Positives = 462/1308 (35%), Gaps = 209/1308 (15%)

Query: 814   PPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
             P D T D     S+ + W  P     + IT Y +    +   S +         +  ++ 
Sbjct: 20876 PTDITKD-----SVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTG 20930

Query: 870   LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWT 928
             L  G +Y   + A  E     P     ETT   ++   PSP D L  +++T   V++ W 
Sbjct: 20931 LSEGCEYFFRVMAENEYGIGEPT----ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWP 20986

Query: 929   PPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHG 983
              P+    S +TGY   VI     G +    +   +     V  L+ G  Y F+V AV+  
Sbjct: 20987 KPKHDGGSKITGY---VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSA 21043

Query: 984   -----RESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
                  RES+P+  ++ T L     L         V+ +         G  + V +   G+
Sbjct: 21044 GRSAPRESRPVIVKEQTMLP---ELDLRGIYQKLVIAK--------AGDNIKVEIPVLGR 21092

Query: 1039  PRQ---YNVGPSVSKYPLR-NLQPASEYTVSLV--AIKGNQESPKAT--------GVFTT 1084
             P+    +  G  + K   R N +  +  T+  +   ++ +      T        G   T
Sbjct: 21093 PKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVIT 21152

Query: 1085  LQ----PGSSIPPYN-TEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSG--- 1136
             +Q    PG    P    EV+   +  +W P    G   GV  S      R+  S +    
Sbjct: 21153 IQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDG---GVPISNYVVEMRQTDSTTWVEL 21209

Query: 1137  -------SIVVSGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEA 1184
                    +   + LT G+EY + ++      +  G      + N       PP    + A
Sbjct: 21210 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 21269

Query: 1185  NPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGL 1241
                   +T+SW    +     I GY +     NG    ++ + +    +      L+ G+
Sbjct: 21270 VTKDS-MTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKAL-VPGNIFKSSGLTDGI 21327

Query: 1242  EYNVSVYTV------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---S 1292
              Y   V         K  K S P+    +  + PP      NI   T+ + WA P     
Sbjct: 21328 AYEFRVIAENMAGKSKPSKPSEPM--LALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGG 21385

Query: 1293  IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
               +T+++V    + N   +     +  +N   ++ L     Y   V +       +P   
Sbjct: 21386 FKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSE 21445

Query: 1353  RQ-----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY 1388
                    +  +++P     + F D        +F            T+ W      + G 
Sbjct: 21446 PSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGT 21505

Query: 1389  -RIRHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIG 1442
              ++      FS     +D       + TLT   PG   +++ ++  L+  G  E PL + 
Sbjct: 21506 AKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVT 21565

Query: 1443  QQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPG 1498
             +                T    ++SW  P       + +Y +   ET   +    +T   
Sbjct: 21566 E---------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVA 21606

Query: 1499  SKSTAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDV 1553
             S+   T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +
Sbjct: 21607 SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTI 21666

Query: 1554  QDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
               +S+ V W        S +  Y V    K G    K            + GL    EY 
Sbjct: 21667 TKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYE 21726

Query: 1610  VSVYAQNPSGESQPLVQT----AVTTI---PAPTDLKFTQVTPTSLSAQWTPP----NVQ 1658
               + A+N +G S P   +    A  T+     P + +    + +S+S  W  P      +
Sbjct: 21727 FRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSE 21786

Query: 1659  LTGYRVRVT-PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--Q 1715
             +TGY V +  P+E    +        ++S  ++GL    +Y++ +YA+       PA   
Sbjct: 21787 ITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVP 21846

Query: 1716  GVVTTLENVSPPR-------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
             G     + + PP        R  VT     T+ +    K       +V     +G++  +
Sbjct: 21847 GTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAP--EVKWARDHGESLDK 21904

Query: 1769  RTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLA 1823
              +I+    SYT  I G     D   Y+ T+ +++ S    ++    +D P    +L+   
Sbjct: 21905 ASIE-STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV-LDTPGPPQDLKVKE 21962

Query: 1824  TTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1879
              T  S+ ++W PP     ++I  YI++  +        V       T   +  L+ G  Y
Sbjct: 21963 VTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVAT-NCHKTSWKVDQLQEGCSY 22021

Query: 1880  TIYVIALKN-------------NQKSEPLIGRKKTGQEAL-SQTTISWA-PFQDTSE--- 1921
                V+A                     PL   K T  +   +  ++SW  P  D      
Sbjct: 22022 YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRIL 22081

Query: 1922  -YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 1968
              YI+     G+D+      V    T AT+TGL +G  Y+  V A  ++
Sbjct: 22082 GYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEK 22127



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 22350 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 22409

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 22410 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 22454

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 22455 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 22514

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 22515 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 22572

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 22573 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 22626

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 22627 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 22683

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 22684 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 22743

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 22744 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 22802

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 22803 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 22862

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 22863 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 22922

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 22923 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 22979

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 22980 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 23034

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 23035 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 23093

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 23094 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 23153

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 23154 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 23211

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 23212 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 23269

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 23270 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 23321

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 23322 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 23381

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
                   + +  L+   EY   ++A+N  G     ES P+V       P P    F T ++
Sbjct: 23382 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 23435

Query: 1645  PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
               S+  QW  P       + GY +    +      K        +      L    +YE 
Sbjct: 23436 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 23495

Query: 1701  SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
              VYA       + ++        +   PP            IT+ W          ITG+
Sbjct: 23496 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 23555

Query: 1755  QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
              V+        P  R +K    +     +T++GL     Y+  +   N
Sbjct: 23556 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 23599



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 27775 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 27834

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 27835 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 27879

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 27880 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 27939

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 27940 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 27994

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 27995 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 28053

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 28054 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 28109

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 28110 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 28168

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 28169 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 28227

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 28228 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 28286

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 28287 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 28345

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 28346 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 28405

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 28406 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 28464

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 28465 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 28523

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 28524 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 28583

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 28584 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 28640

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 28641 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 28696

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 28697 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 28748

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 28749 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
              +EY   V ++N  G S+PL    +      +P  APT  +   V+  ++S +W  P   
Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 28867

Query: 1656  -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
                ++ GY V    +     +KE  +     +  V+GL+   +Y+   YAL     S+ +
Sbjct: 28868 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 28927

Query: 1715  QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
             +    +     V  P R  VTD T +T+++ W          + G+ ++  P +      
Sbjct: 28928 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 28987

Query: 1764  QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
                   TI  D   +T+T L  G  Y+  +   N
Sbjct: 28988 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 29020



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)

Query: 1412  SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
             S  +T L  G EY   I+A+N        E  P++      V D P+  EV   T  S++
Sbjct: 22695 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 22754

Query: 1466  ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             + W+ PA      +  Y +   +  G    +       +    ++GL    DY   V A 
Sbjct: 22755 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 22814

Query: 1522  TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
                G    SP S+   + +   +   P+  +V D+  +S+ + W          + GY V
Sbjct: 22815 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 22874

Query: 1575  TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
                  + G     T   G ++T + +E L    EY   + A N +G  +        +V+
Sbjct: 22875 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 22934

Query: 1627  TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
               +       DL+  ++                   + R TP+ K     G +++  +  
Sbjct: 22935 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 22990

Query: 1683  DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
              +SS     L    +Y+   Y L  +++  ++ A   V  L+  SPP   +VT+ T+ ++
Sbjct: 22991 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 23050

Query: 1741  TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
             +I+W          I  + V+   A  ++           S+ I  LQ G  Y   +   
Sbjct: 23051 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 23110

Query: 1797  NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
             N+     P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +
Sbjct: 23111 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 23170

Query: 1849  KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                S       R +    +A IT L  G EY   V+A+    +S+P
Sbjct: 23171 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 23214



 Score = 78.6 bits (192), Expect = 6e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 26068 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 26127

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 26128 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 26179

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 26180 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 26231

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 26232 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 26289

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 26290 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 26349

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 26350 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 26406

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 26407 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 26460

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 26461 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 26511

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 26512 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 26571

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 26631

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 26632 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 26690

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 26746

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 26747 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 26791



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 278/1381 (20%), Positives = 487/1381 (35%), Gaps = 191/1381 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 17271 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 17327

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 17328 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 17386

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 17387 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 17446

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 17447 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 17504

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 17505 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 17559

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 17560 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 17617

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 17618 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 17677

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 17678 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 17737

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 17738 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 17797

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 17798 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 17856

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 17857 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 17916

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 17917 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 17974

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 17975 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 18025

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 18026 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 18083

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 18084 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 18143

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 18144 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 18201

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 18202 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 18251

Query: 1599  IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
             I+    + ++ ++           V A N +G         V   P P  +LK   V+  
Sbjct: 18252 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 18311

Query: 1647  SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
               +  W PP     G  ++    EK    K +  +  S++V+  G  V    E + Y  +
Sbjct: 18312 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 18369

Query: 1707  DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
                 ++   G  T  + V           P    VT  ++  +T+ W        ++ITG
Sbjct: 18370 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 18429

Query: 1754  FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
             + ++    +     P+ ++  P+ R   +  L P  +Y+  +   N+      +  S PV
Sbjct: 18430 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 18488

Query: 1806  VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
             V  D       P+N R + TT +S+ + W  P     A I GY+++       + P E  
Sbjct: 18489 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 18548

Query: 1859  PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWA 1914
              R          E T+T L+   EY   V A     +++  IGR    +EA+    I   
Sbjct: 18549 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA-----QNQVGIGRPAELKEAIKPKEILEP 18603

Query: 1915  P 1915
             P
Sbjct: 18604 P 18604



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 210/1000 (21%), Positives = 366/1000 (36%), Gaps = 157/1000 (15%)

Query: 1092  PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
             P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 13092 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 13151

Query: 1142  GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
             GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 13152 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 13209

Query: 1194  SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 13210 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 13268

Query: 1251  KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
                    P + T    V        PP +L  ++    ++++ W PP     S  L   +
Sbjct: 13269 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 13328

Query: 1300  VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
              R    K+      + + P +    +T L  G +Y+  VS+  +   S P         D
Sbjct: 13329 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 13387

Query: 1360  SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
                     D++A    +  I P           +P   +     D+V  + + + +  L+
Sbjct: 13388 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 13447

Query: 1420  PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
                E V+S    + +    L L  +  T+S             P++L+    T  S+ ++
Sbjct: 13448 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 13507

Query: 1468  WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
             W+ P            +  G SP+  + V   + +                T+  L  G 
Sbjct: 13508 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 13555

Query: 1513  DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
             +Y   V A    G G+     +P++++    + D P  ++  D   NSI + W P     
Sbjct: 13556 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 13615

Query: 1566  SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              S + GY V   P+   G  K    G    +T+M + GL+    Y   V A N  G S+P
Sbjct: 13616 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 13672

Query: 1624  LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
                T    AV T  AP           L     T   L A  T  P  ++T  +  +  K
Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 13732

Query: 1670  EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
             +     K I +   P  S+V +   + + + +   Y ++       A  VV    L+   
Sbjct: 13733 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 13785

Query: 1726  PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
             PP    +TD T  +  ++W    +     IT + V+    + +    +  T+K    ++ 
Sbjct: 13786 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 13843

Query: 1780  ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
              T L P  +Y        +Y + +  ++SP  I A    D    P+ L     T +++ +
Sbjct: 13844 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 13901

Query: 1832  SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
             +W  P     + ITGY ++   P +       +     T   + GL    +Y   V+A  
Sbjct: 13902 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 13961

Query: 1887  -----KNNQKSEPLI-----------GRKKTGQEALSQTTISWA-PFQD----TSEYIIS 1925
                  K ++ +EP++           G+        +   ++W  P  D       Y+I 
Sbjct: 13962 LAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIE 14021

Query: 1926  CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                 GTDE  ++      +T   L GL  G  Y+  V A+
Sbjct: 14022 MLKTGTDEW-VRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 14060



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 316/1566 (20%), Positives = 536/1566 (34%), Gaps = 237/1566 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
             P  V +T+T     S  ++W+ P       I  YI+    K  +G W +      + + Y
Sbjct: 28257 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 28313

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
             T+  L+ G  Y+ ++ +I   G  +         S     T   V   T P   + A  +
Sbjct: 28314 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 28364

Query: 727   SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
                 + A + +  +++     + T    + +  LS   D     D  ST T  N      
Sbjct: 28365 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 28423

Query: 783   GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
             G KY + V   S  G +S+  +      P  P   T   V   S  + W  P     A I
Sbjct: 28424 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 28480

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
               Y +    +   S   ++   T     ++DL  GV Y   + AV E     P  + +  
Sbjct: 28481 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 28540

Query: 899   TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
               T +      PR L  V+ +     + W  P+    S +TGY +++        +   H
Sbjct: 28541 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 28597

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
              ++L  +     E T       Y F+V A +    S+P  A  +  +  P          
Sbjct: 28598 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 28642

Query: 1011  STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
                      P A +TG    +   + G P   +V       P V+ + L  ++      V
Sbjct: 28643 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 28694

Query: 1065  SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
             S+   K       ++S +      F TL+  + +  ++      T+V+   P P  G   
Sbjct: 28695 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 28749

Query: 1115  ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
                          G  P  GG    E+T+      +SG+              I V+ LT
Sbjct: 28750 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 28806

Query: 1145  PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
               +EY + +    R G  +    API+  +  V P +P  P   H+ AN     +++ WE
Sbjct: 28807 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 28862

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
                     G +I       ++ N++    E  V   + +     L  GLEY    Y +  
Sbjct: 28863 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 28920

Query: 1251  ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
                 K  + S PI       V  P     T++   T+ + W+ P       +  +++   
Sbjct: 28921 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 28978

Query: 1304  PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
             PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+  R
Sbjct: 28979 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 29038

Query: 1354  Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
                   K  LD+    D   I A S  V   A    P   I   +     +       + 
Sbjct: 29039 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 29098

Query: 1405  RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
                 +   I   + +   +Y +++   +G +   +++     V D P     L V   T 
Sbjct: 29099 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 29154

Query: 1462  TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
                 ++W  P       + +Y +   ET   S +    V G   T +  ++ L    +Y 
Sbjct: 29155 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 29211

Query: 1516  ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
               V AV   G   P  S+PI       I  P  + +        I ++W    S     +
Sbjct: 29212 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 29271

Query: 1570  TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             + Y V    K     T+  K      T + +  L    +Y   V A N +G S+P   + 
Sbjct: 29272 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 29331

Query: 1629  VT-------TIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK- 1676
                      T   P+  +    T  S+S  WT P       + GY + +  K+     + 
Sbjct: 29332 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 29391

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTD 1734
               N    ++   V  L +  KY   V A+     S  ++ +  +  +E +  P    + D
Sbjct: 29392 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD-LELAD 29450

Query: 1735  ATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
               + T+TI        +        P       G     R I     SY++  +     Y
Sbjct: 29451 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 29510

Query: 1790  KIYLYTL---NDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPR----ARIT 1841
                 YT+   N + + S  V+        P  +++    + +S+ ++W+ P     A + 
Sbjct: 29511 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVN 29570

Query: 1842  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP------- 1894
              YI++  +      + V   +   T   I+GL  GT Y   V+        EP       
Sbjct: 29571 NYIVEKREAAMRAFKTVTT-KCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAV 29629

Query: 1895  ------LIGRKKTGQEALSQT-TISWA-PFQDTSE----YIISCHPVGTDEEPLQFRVPG 1942
                   L+  K    +    T T++W  P  D       Y++     GT+       +  
Sbjct: 29630 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 29689

Query: 1943  TSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTV 2002
             T    T+T L  G  Y   + A  ++   + RE V  V  +V +    PT D    P   
Sbjct: 29690 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAV--TVQDLRVLPTIDLSTMPQKT 29747

Query: 2003  SHYAVG 2008
              H   G
Sbjct: 29748 IHVPAG 29753



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 26527 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 26581

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 26582 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 26641

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 26642 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 26699

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 26700 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 26756

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 26757 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 26814

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 26815 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 26874

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 26875 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 26930

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 26931 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 26990

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 26991 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 27050

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 27051 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 27106

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 27107 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 27164

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 27165 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 27282

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 27283 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 27342

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 27343 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 27459

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 27460 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 27516

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
             T E+ +  L+        V+A+N  G S P+      TI  P  +K   +TP   LS   
Sbjct: 27517 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 27566

Query: 1653  TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
               P  Q+T   G+ V +    K  P   I+   D   +  S  +  +K E  +  ++K+ 
Sbjct: 27567 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 27626

Query: 1709  LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
                   +             V  T+  + PP +     R  +    ++ +SW    +   
Sbjct: 27627 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 27686

Query: 1751  --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
               IT + ++      QT  +       R ++ +  L    +Y+  +   N    S P+V 
Sbjct: 27687 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 27745

Query: 1808  DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
                 A         P        T + + ++W  P     + +TG+ ++ ++  S   + 
Sbjct: 27746 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 27805

Query: 1858  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             V        E   TGL  G +Y   V A  +   S P
Sbjct: 27806 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 27842



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602   LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
             ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 15492 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 15549

Query: 658   TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
             T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 15550 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 15602

Query: 718   FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
               P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 15603 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 15656

Query: 773   ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                    N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 15657 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 15716

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
               +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 15717 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 15776

Query: 876   YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
             Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 15777 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 15808



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 30726 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 30780

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 30781 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 30840

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 30841 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 30900

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 30901 CENLGGESEWSEISEPI--TPKSD 30922



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 31109 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 31166

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 31167 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 31226

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 31227 EVDETREVSMT 31237



 Score = 35.8 bits (81), Expect = 0.47
 Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)

Query: 1534  ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
             + +  + + DKP+   V + +  NS  + W P +    S +T Y V           +  
Sbjct: 30715 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 30774

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
             ++    T   I  L     Y   V AQN  G S PL  ++V  I +P +          T
Sbjct: 30775 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 30834

Query: 1642  QVTPTSLSAQWTPP 1655
              VT  S    W PP
Sbjct: 30835 AVTKDSCVVAWKPP 30848


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score =  149 bits (376), Expect = 3e-35
 Identities = 294/1431 (20%), Positives = 527/1431 (36%), Gaps = 186/1431 (12%)

Query: 607   SSSGPVEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGR 653
             S S  +++ + + P  P S  I           W  P     S I+ YI+  R + S   
Sbjct: 13071 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKR-ETSRPN 13129

Query: 654   WKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
             W + +    + S +++ L  G  Y+ ++ +  +YG                PV +     
Sbjct: 13130 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYG-------------VGDPVFTEPAIA 13176

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLP 769
             +     P       ++ IT     VSW   +D     ++G+ +E   ++  +  +    P
Sbjct: 13177 KNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKP 13236

Query: 770   STATSVNIPDLLPGRKYIVNVYQISE--DGEQSLILSTSQTTAPDAPPDPTV-DQVDDT- 825
                 ++    L  G +Y   V  I++   G+ S     +    P  PP P    +V DT 
Sbjct: 13237 IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTT 13296

Query: 826   --SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT--LSDLQPGVQYN 877
               S+ + W +P     +PI GY +    +   +    NLP+        ++ L    QY 
Sbjct: 13297 RSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQ 13356

Query: 878   ITIYAVEENQESTPVVIQQETTGTPRSDTVPSP----RDLQFVEVTDVKVTI-MWTP--- 929
               +YAV +   S P  +  +    P+   +P       DL+   +    VT+ ++ P   
Sbjct: 13357 FRVYAVNKIGYSDPSDVPDKHY--PKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKG 13414

Query: 930   -PESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSP-GVTYYFKVFAVSHGRES 986
              P   +T  + +V   NL    G  +  +  +TF     ++      Y      S G++ 
Sbjct: 13415 RPPPKITWSKPNV---NLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 13471

Query: 987   KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY 1042
               +  +       P N+     +  +  V W PP     + I  Y +      R      
Sbjct: 13472 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13531

Query: 1043  NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
                 S + + + NL+    Y   + A               V  +  PG  +      V+
Sbjct: 13532 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 13591

Query: 1100  ETTIVITWTPAPR------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
             +++  I W           IG+ +     +  +  R + S S       LT G EY + +
Sbjct: 13592 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSAKDLTEGKEYTFRV 13650

Query: 1154  QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL-------------------TVS 1194
                 +  E     +  V        +L L+  PD   L                   +VS
Sbjct: 13651 SAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13710

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD-NLSPGLEYNVSVYTVKDD 1253
             W++   P  T  R++             E    + +   +D   S   +Y +++  V   
Sbjct: 13711 WKKGEDPLATDTRVSV------------ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 13758

Query: 1254  KESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             KE   IS  ++     PT  ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 13759 KEGT-ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13817

Query: 1310  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1363
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 13818 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13876

Query: 1364  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 13877 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13936

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS----DVPRDLEVVAATPTSLLISWDAPAVTV 1475
              G EY   ++A+N        +  +  V+    D P   EV+  T  S+ + W  P    
Sbjct: 13937 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13996

Query: 1476  RY----YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
              +    Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 13997 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 14056

Query: 1532  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1575
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 14057 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 14116

Query: 1576  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAP 1635
                   P      T+ P  + +TI+          ++ A NP G     V+  V  +P P
Sbjct: 14117 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 14170

Query: 1636  TD-LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVS 1690
                ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V +
Sbjct: 14171 PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14229

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRT 1746
              L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+ 
Sbjct: 14230 KLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKR 14289

Query: 1747  KTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLN--- 1797
               +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N   
Sbjct: 14290 PVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAG 14348

Query: 1798  ----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1849
                   A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K
Sbjct: 14349 IGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 14408

Query: 1850  PGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
              G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14409 VGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14456



 Score =  148 bits (373), Expect = 7e-35
 Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 22915 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22973

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 22974 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 23023

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 23024 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23080

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 23081 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23140

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 23141 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23200

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 23201 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23252

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 23253 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23311

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 23312 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23369

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 23370 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23428

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 23429 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23488

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 23489 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23548

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 23549 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23606

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 23607 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23666

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 23667 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23726

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 23727 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23786

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 23787 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23838

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 23839 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23897

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 23898 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23956

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 23957 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 24013

Query: 1629  VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
               T   P +         +   VT +S+S  W+ P      ++TGY +          ++
Sbjct: 24014 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24073

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
                    ++   V+GL+   +Y+  + A  D   + TS  ++ VV     +  S P    
Sbjct: 24074 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24133

Query: 1732  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
             +   ++ ++T+ W        + I G+ V+    +G +  +++ K  +  + +TI GL  
Sbjct: 24134 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 24192

Query: 1786  GTDYKIYLYTLNDNARSSP 1804
              T+Y+  ++  N+   S P
Sbjct: 24193 ATEYEFRVFAENETGLSRP 24211



 Score =  138 bits (347), Expect = 7e-32
 Identities = 290/1321 (21%), Positives = 498/1321 (37%), Gaps = 189/1321 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13485 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13541

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13542 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13586

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13587 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13643

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13644 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13703

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13704 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13761 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13813

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13814 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13872

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13988

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 13989 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 14048

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 14049 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14107

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 14108 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14160

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 14161 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14210

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 14211 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14270

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 14271 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14330

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 14331 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14390

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 14391 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14450

Query: 1526  -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 14451 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14510

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V   P P  +
Sbjct: 14511 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14568

Query: 1638  LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
             L+ T +T  S++  W  P +    ++T Y V    +++    K  + A       +  V+
Sbjct: 14569 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 14624

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
             GL    +Y   V A  +     P +    V   E  SPP    + D T++T++++W    
Sbjct: 14625 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 14684

Query: 1745  RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
                   ITG+ ++A    + Q     T+K       +  L  G +Y   +  +N   RS+
Sbjct: 14685 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 14742

Query: 1804  P 1804
             P
Sbjct: 14743 P 14743



 Score =  129 bits (323), Expect = 4e-29
 Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7471 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7529

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7576

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7577 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7636

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7637 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7696

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7754

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7755 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7814

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7815 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7873

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7874 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7933

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7934 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7993

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7994 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 8052

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 8053 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8106

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 8107 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8165

Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
             I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 8166 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8225

Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
              +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8285

Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
             TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 8286 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8343

Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
            EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 8344 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8403

Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
              IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 8404 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8463

Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
            +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 8464 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8523

Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 8524 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8583

Query: 1624 LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
             V   +          AP       VT  S+  +W  P      + GY +       T  
Sbjct: 8584 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8643

Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
             +      ++    V GL+    Y   V A       +  P     T  + +SPP     
Sbjct: 8644 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 8703

Query: 1731 RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
            RVTD + TTI + W          I G+ VD          + T K   VR YT+  ++ 
Sbjct: 8704 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 8763

Query: 1786 GTDYKIYLYTLNDNARSSP 1804
            G DYK+ +  +N      P
Sbjct: 8764 GADYKLRVSAVNAAGEGPP 8782



 Score =  129 bits (323), Expect = 4e-29
 Identities = 261/1302 (20%), Positives = 465/1302 (35%), Gaps = 162/1302 (12%)

Query: 716   TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--- 772
             TP  P+  T   V EI+  S  V+W           + Y + +   E +     +T    
Sbjct: 13481 TPGPPVNVT---VKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSK 13537

Query: 773   TSVNIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  + +L  G+ Y   V     Y I + GE    +  SQT  P    D  V  V  +S 
Sbjct: 13538 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV--DLKVRSVSKSSC 13595

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
              + W +P +     I GY + +    E +  +  +   +   +  DL  G +Y   + A 
Sbjct: 13596 SIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAE 13653

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              EN E TP     E T   R D V    DL+ +        + +   E++    ++ +  
Sbjct: 13654 NENGEGTP----SEITVVARDDVVAPDLDLKGLP------DLCYLAKENSNFRLKIPIKG 13703

Query: 944   VNLPGEHGQRL--PISRNTFAEVTGLSPGVTY------------YFKVFAVSHGRESKPL 989
                P    ++   P++ +T   V   +   T             Y        G +   +
Sbjct: 13704 KPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 13763

Query: 990   TAQQTTKLDAPTN-LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNV 1044
             + +   K   PT  ++F   T   + ++W PP+    ++IT Y L    +   +      
Sbjct: 13764 SIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCAS 13823

Query: 1045  GPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKATGVFTTLQ---PGSSIPPYNTEVT 1099
                 + + +  L    EYT  + A    G  E  K+  +        P +  PP   +V 
Sbjct: 13824 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVR 13883

Query: 1100  ETTIVITWTPAPRIG--------FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
               ++ +TWT   + G         +   R S   +   +         V+GLT G+EY +
Sbjct: 13884 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13943

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTTPD---ITGY 1206
              +  +         + ++ V  L P  P       N     +T+ W          +TGY
Sbjct: 13944 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 14003

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEYNV---------SVYTVKDDKE 1255
              +       +   S  +  H +   C F   +L  G +Y           ++    +  E
Sbjct: 14004 IVEKRDLPSK---SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTE 14060

Query: 1256  SVPISD-----TII--PAVPPPTDLRFTN-IGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
             ++   D     TI+  P +     ++  + I  + + +   P P    +       P   
Sbjct: 14061 TIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP--- 14117

Query: 1308  EEDVAELSISPSDNAVVL--TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD---SPT 1362
               D+ +++ +P+ + + +         EY ++ ++ +     T +   + T LD    P 
Sbjct: 14118 -SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF----GTKVEHVKVTVLDVPGPPG 14172

Query: 1363  GIDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTN 1417
              ++ S+++A   T+ W  P     + I  Y + +            + +   R+    T 
Sbjct: 14173 PVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH--VATK 14230

Query: 1418  LTPGTEYVVSIVALN--GREE----SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L  G EY+  + A+N  G+ E     P+ +  +      P   EV   T  +  +SW  P
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14290

Query: 1472  A----VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    +  Y +   E      V+    P S     ++GL+ G  Y   V A    G  
Sbjct: 14291 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350

Query: 1528  PASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1580
             P S    S+  +        PS   VTD    S S+ W          +TGY V    K 
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY-VVEHQKV 14409

Query: 1581  GPGPTKTKTAGPDQ--TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL 1638
             G       T G     T+  +  LQ   +Y   + A N +G  +P V      IP    +
Sbjct: 14410 GDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV------IPDVEIV 14463

Query: 1639  KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS------------SS 1686
             +        L A+     V   G  +R+    K  P  E+    D+             S
Sbjct: 14464 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTES 14523

Query: 1687  VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDATETTITISW 1744
               +  +    +Y+   + +     +    G V    L+   P    R TD T+ ++T+ W
Sbjct: 14524 FTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHW 14583

Query: 1745  RTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
                       IT + V+   A  ++    T K    +Y +TGL  G +Y   +   N+  
Sbjct: 14584 DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYG 14643

Query: 1801  RSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1852
                P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY+I+ ++ GS
Sbjct: 14644 IGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS 14703

Query: 1853  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                  +   +    E  +  L  G EYT  V+A+ +  +S P
Sbjct: 14704 DQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAP 14743



 Score =  128 bits (321), Expect = 7e-29
 Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)

Query: 758  EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
            E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 7131 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7186

Query: 815  PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
             +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 7187 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7246

Query: 871  QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
              G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 7247 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7306

Query: 931  E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 7307 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7365

Query: 987  KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
            KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7420

Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 7421 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7473

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
             V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 7474 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7530

Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
             V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 7531 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7589

Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 7590 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7648

Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
               V         K  K + P  I D I P  PP  PT     ++G  ++R+ W  P   
Sbjct: 7649 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 7705

Query: 1292 -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
                + ++++       +E V      P+    +L  L+ G EY   V +V +  E    
Sbjct: 7706 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 7764

Query: 1347 --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
              S P+  R+K    S P  ++  +IT N+  + W  P     + IT Y +        G
Sbjct: 7765 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7824

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
                D         T+T LT G+ YV  + A N          E  +L     T    P 
Sbjct: 7825 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7883

Query: 1453 DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
             L VV  T   + + W+ P       ++ Y I   E  G   V+     G      ++ +
Sbjct: 7884 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7943

Query: 1509 KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
              G +    V A    G G     ++ +SI   T    P   + VTD     I++ W P 
Sbjct: 7944 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 8003

Query: 1565 ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
                 SP+ GY V   P       +  +      +  + EG+ P  EYV+ V A N  G 
Sbjct: 8004 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 8063

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
            S+P  + +   +    D K T    T          + + G ++ +    +  P+  ++ 
Sbjct: 8064 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 8115

Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
              D   V  S  +      +S + L+   + R   G+ T TLEN                
Sbjct: 8116 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174

Query: 1724 VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
              P +  + +D T+++  ++W          I  + ++   A  +T I      +  S+T
Sbjct: 8175 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8234

Query: 1780 ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
            +  L P  +Y   +  +N          ++  +  D     D P ++     T  ++ ++
Sbjct: 8235 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8294

Query: 1833 WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
            W+PP     ++I GYII+    G    +        +   T  GLE G EY   V A   
Sbjct: 8295 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8354

Query: 1889 NQKSEP 1894
               SEP
Sbjct: 8355 AGISEP 8360



 Score =  128 bits (321), Expect = 7e-29
 Identities = 299/1394 (21%), Positives = 524/1394 (37%), Gaps = 194/1394 (13%)

Query: 604   TYPSSSGPVEVFIT----ETPSQP----------NSHPIQWNAPQ---PSHISKYILRWR 646
             T  +SSG    F+T    +TPS P          +S  I W  P     S I  YI+  R
Sbjct: 16709 TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKR 16768

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
                    +       H NS+ I  L+ G  Y  ++ +  +YG             T+ P+
Sbjct: 16769 EATRKS-YAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-------LPAQTADPI 16820

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
                 V        P      +V ++T +S  +SW           ++Y +  +    +  
Sbjct: 16821 KVAEV--------PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW 16872

Query: 767   DLPSTATSVN--IPDLLPGRKYIVNVYQISEDGE---QSL---ILSTSQTTAPDAPP--- 815
                +   S+   I +L  G +Y+  V  ++E G    +SL   I++      PD  P   
Sbjct: 16873 SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFS 16932

Query: 816   DPTVDQVDDTSIVVRWS-RPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP-- 872
               +V    D  I V  S RP+  IT  +          +T +N+ ++ +  TLS  +   
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVTDSLDLTTLSIKETHK 16989

Query: 873   --GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
               G QY IT+  V   + ++  ++  +    P+         ++F +V+   +T+ W PP
Sbjct: 16990 DDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGP-------VKFDDVSAESITLSWNPP 17042

Query: 931   ----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAV-----S 981
                    +T Y V                ++R T  +VT L  G  Y F++FA      S
Sbjct: 17043 LYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTL-KVTKLKTGTEYQFRIFAENRYGQS 17101

Query: 982   HGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTRR 1036
                ES P+ AQ   K   P    F    +  +++++W  P     + + GY L      R
Sbjct: 17102 FALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE--RKER 17159

Query: 1037  GQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI 1091
                    V  ++   +++  +NL+   EY   + A  I G  ++ K +  +    P    
Sbjct: 17160 NSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD-- 17217

Query: 1092  PPYNTE---VTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             PP   E   V    I + WT     G  +       G    +     G  + +  T  +E
Sbjct: 17218 PPGTPEPIMVKRNEITLQWTKPVYDGGSMIT-----GYIVEKRDLPDGRWMKASFTNVIE 17272

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPTNL-------------HLEANP---DTGVL 1191
               +T+  L + Q  +  ++ K     +S P++               +  +P   DT V+
Sbjct: 17273 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVV 17332

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS--------PGLEY 1243
                       D+ G  + T     +    +EE    +  +  F  L          G +Y
Sbjct: 17333 NAGETFRLEADVHGKPLPTIEWL-RGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17391

Query: 1244  NVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPP---PSIDLTNFL 1299
              +    V   K S P++  ++    PP   ++ T +  +   +TW+PP      D+++++
Sbjct: 17392 ILRASNVAGSK-SFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYV 17450

Query: 1300  VRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVY-----EQHESTPLR 1351
             V     K E      ++  S+   N++ +T LL G EYV  + +V      E  ES P+ 
Sbjct: 17451 VE----KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17506

Query: 1352  GRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSG----RPR 1402
              +    L   P  ++ ++I  +S TV W  P     + I GY +       SG    +  
Sbjct: 17507 MKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDR--SGIRWIKCN 17564

Query: 1403  EDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---EESPLLIGQQST----VSDVPRDLE 1455
             + R+   R  + +T LT   EY   + A N     E SP  +  ++         P +  
Sbjct: 17565 KRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAH 17622

Query: 1456  VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV----PGSKSTA-TISGLKP 1510
             +V  T  S+ ++W  P        + Y      +  +E+ +     G + T   IS L  
Sbjct: 17623 IVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTE 17682

Query: 1511  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1567
               +Y I V A+   G   A+S P ++    +++ P ++ +       I V+   S+    
Sbjct: 17683 HQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVRAGGSARIHI 17741

Query: 1568  PVTGY---RVTTTPKNGPGPTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
             P  G     +T + + G    K +   G + T+++I+           +  +N SG    
Sbjct: 17742 PFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 17801

Query: 1624  LVQTAVTTIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINL 1680
              V   V   P  P +L   +V   S    W PP +   G +V+  V  K ++      N+
Sbjct: 17802 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID-GGAKVKNYVIDKRESTRKAYANV 17860

Query: 1681  APDSS--SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDAT 1736
             +   S  S  V  L     Y   V A  +     P + V  V   E  SPP +  +TD +
Sbjct: 17861 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17920

Query: 1737  ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1792
             +T+ ++ W          + G+ V+  P  G        +  V +  +TGL  G +Y+  
Sbjct: 17921 QTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEKWSIVAESKVCNAVVTGLSSGQEYQFR 17979

Query: 1793  LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1852
             +   N+  +S P V      +  P   + L   P SL + +     +  G  +K E P  
Sbjct: 17980 VKAYNEKGKSDPRV------LGVPVIAKDLTIQP-SLKLPFNTYSIQ-AGEDLKIEIP-- 18029

Query: 1853  PPREVVPRPRPGVT 1866
                 V+ RPRP ++
Sbjct: 18030 ----VIGRPRPNIS 18039



 Score =  128 bits (321), Expect = 7e-29
 Identities = 307/1365 (22%), Positives = 489/1365 (35%), Gaps = 211/1365 (15%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 17773 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17830

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 17831 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17890

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 17891 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17946

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 17947 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 18004

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 18056

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 18057 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 18114

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 18115 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 18171

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 18172 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18230

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 18231 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18289

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 18290 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18346

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 18347 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18395

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 18396 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18454

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 18455 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18514

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 18515 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18573

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 18574 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18633

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 18634 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18693

Query: 1628  AVTTIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP- 1682
             A+     P++ K T  + +S+S  W+ P       + GY V V  KE           P 
Sbjct: 18694 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--KEAAADEWTTCTPPT 18751

Query: 1683  --DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP--------RRA 1730
                     V+ L   T+Y   + A+       PA   G V   E + PP        R+ 
Sbjct: 18752 GLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKV 18811

Query: 1731  RVTDATETT---ITISWR----TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1783
              V  A+ T    +TI  R     K E   G   D       +     +  +V  +     
Sbjct: 18812 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRF----- 18866

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR--- 1837
                 D   Y  TL +N+ S    ++    +D+PS   NL       +S+ +SW+PP    
Sbjct: 18867 ----DSGRYNLTLENNSGSKTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDG 18921

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT--ITGLEPGTEYTIYVIALKNN----- 1889
              A+IT YI++  +     R+         T+ T  I  L+ G  Y   V+A         
Sbjct: 18922 GAKITNYIVEKRET---TRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLP 18978

Query: 1890  -------QKSEPLI--GRKKTGQEALSQTTISWA-PFQDTSE----YIISCHPVGTDEEP 1935
                    + SEP +  GR        +  TI W  P  D       Y++     G+++  
Sbjct: 18979 AETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS 19038

Query: 1936  LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 1980
                +V   +  AT++GLT G  Y   V A+ ++ R   R+  V V
Sbjct: 19039 TCTQVK--TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 19081



 Score =  127 bits (318), Expect = 2e-28
 Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 12000 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 12058

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 12059 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12118

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 12119 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12176

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 12177 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12236

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 12237 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12295

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 12296 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12354

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 12355 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12412

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 12413 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12469

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 12470 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12528

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 12529 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12587

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 12588 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12641

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 12642 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12701

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 12702 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12760

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 12761 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12810

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 12811 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12868

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 12869 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12928

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
                 +  TA     Q E T  GL+   +Y           + + + +TAV   P   P+D
Sbjct: 12929 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 12977

Query: 1638  LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
                    P ++ A+  PP + L+   +  +T K  T           PM  ++   D + 
Sbjct: 12978 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 13030

Query: 1687  V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
             +    G+ +A +  +    L     KD    T+T+  + G       +  L+   PP   
Sbjct: 13031 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13090

Query: 1731  RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
             ++         +SW    E     IT + VD    +     Q +    + S ++  L  G
Sbjct: 13091 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 13150

Query: 1787  TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
              +Y+  +   N      PV  +   A    D P           T + + VSW+PP    
Sbjct: 13151 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 13210

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
              + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A+      +P
Sbjct: 13211 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 13268



 Score =  125 bits (314), Expect = 5e-28
 Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 14281 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14339

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 14340 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14387

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 14388 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14445

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 14446 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14502

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 14503 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14556

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 14557 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14616

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 14617 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14675

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 14676 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14733

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 14734 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14793

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 14794 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14853

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 14854 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14913

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
               T   L+ GLEY   V           I+   I A     VP PP   + T +  D+M 
Sbjct: 14914 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14971

Query: 1285  VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
             ++W  P S   +  L  +   K    +   ++S +    N    + L  G  Y   V + 
Sbjct: 14972 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 15031

Query: 1342  YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
                 +S P +  +       +D P      +IT ++ T+ W  P  T    IT Y +   
Sbjct: 15032 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15091

Query: 1394  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
                     + +      N  T++ LT    Y   ++A N        I   S  SD    
Sbjct: 15092 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 15147

Query: 1454  LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
              + V A    + + +    +      +R+    +G   P  E++  G +   T       
Sbjct: 15148 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15207

Query: 1512  VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
              D++  +           A T    +P        N +  +D+P      + VT+V    
Sbjct: 15208 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 15266

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
               + W P      + +  Y V     +    T   +     T++ +  L    EY+  V 
Sbjct: 15267 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 15325

Query: 1614  AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
             A N  G  +PL    V  +        P + + T +T  S+   W  P+     ++  Y 
Sbjct: 15326 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 15385

Query: 1664  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
             V    K     +K            VSGL    +YE  + A      S P+         
Sbjct: 15386 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15445

Query: 1719  TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
              T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P
Sbjct: 15446 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 15502

Query: 1774  DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
                    SYTITGL    +YKI +Y +N      P ++
Sbjct: 15503 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15540



 Score =  123 bits (308), Expect = 2e-27
 Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13179

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 13180 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13239

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13240 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13299

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13300 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13359

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13360 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13418

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13479 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13536

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13537 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13593

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13594 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13648

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 13649 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13705

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 13706 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13756

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 13757 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13813

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 13814 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13873

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 13874 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13933

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 13934 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13993

Query: 1563  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 13994 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 14053

Query: 1623  PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
                ++  T I      APT +         L+ +     + L    +   P  K+   K 
Sbjct: 14054 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 14111

Query: 1677  ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
                       +I   P SS + +     AT+ +   Y +  T    ++     VT L+  
Sbjct: 14112 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 14168

Query: 1725  SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
              PP    +++ +    T++W    E         +    +T   +   +  D++S  +  
Sbjct: 14169 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 14228

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
             T L  G +Y   +  +N   +  PV  +    +D       P        T N+  VSW+
Sbjct: 14229 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 14288

Query: 1835  PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
              P     + ITGY ++  +  S       +         +TGL+ G+ Y   V A
Sbjct: 14289 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 14343



 Score =  120 bits (300), Expect = 2e-26
 Identities = 273/1236 (22%), Positives = 459/1236 (37%), Gaps = 166/1236 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20844

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20845 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20900

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20901 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20957

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20958 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 21008

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 21009 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21067

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 21068 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21127

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 21128 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21183

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 21184 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21243

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 21244 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21300

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 21301 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21356

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 21357 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21415

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 21416 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21475

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 21476 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21535

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 21536 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21595

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T    +P   +
Sbjct: 21596 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 21654

Query: 1638  ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
                       +K  +        Q  P   ++T ++  V  +++     EI     S+S+
Sbjct: 21655 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 21711

Query: 1688  VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
              V     AT+    VY ++    S  A+  +      +P +     R T+ T   +T+ W
Sbjct: 21712 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21768

Query: 1745  RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
                       IT + ++    +         K + +SYT   L  G +Y+  +  +N   
Sbjct: 21769 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 21828

Query: 1799  ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
                   S PVV     T  DAP        T NS+ ++W  P     + I  YI+ + EK
Sbjct: 21829 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 21888

Query: 1850  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
               +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 21889 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 21924



 Score =  118 bits (295), Expect = 7e-26
 Identities = 345/1615 (21%), Positives = 576/1615 (35%), Gaps = 251/1615 (15%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 22654 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22712

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 22713 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22762

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 22763 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22818

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 22819 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22876

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 22877 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22927

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 22928 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22987

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 22988 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 23047

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 23048 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 23107

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 23108 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 23161

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 23162 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23221

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 23222 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23272

Query: 1222  EEVVHADQS-----SCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTIIPAVPP-- 1269
             E  + A ++     S T   +S  +E  +  + V  +      E    SD ++ +  P  
Sbjct: 23273 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23332

Query: 1270  PTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
             P  L   ++   T+ + W  P       LT +++       E  +  +++ P+     +T
Sbjct: 23333 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23392

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI-TANSFTVHWIAPRATI 1385
             +L  G +Y+  + +  E+  S P        +     +   D+ T    T+H  A R   
Sbjct: 23393 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVE 23452

Query: 1386  TGYRIRHHPE-----HFSGRPR--------EDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
                 I   P       F+G           E     ++ +I  T +    EY + +  + 
Sbjct: 23453 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 23512

Query: 1433  GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
             G     + +            +++     TS+ ISW+ P            E  G +P+ 
Sbjct: 23513 GTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP------------ELDGGAPLS 23560

Query: 1493  EFTV-------PG--------SKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI 1536
              + V       PG        ++ST   + L  G +Y   V A    G  S   S+ I  
Sbjct: 23561 GYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 23620

Query: 1537  NYRTEIDKPSQ-MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
                  I  P + +Q+ DV  + +++ W P      S VTGY V           +     
Sbjct: 23621 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 23680

Query: 1592  PDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA-PTDLKFTQVT 1644
                T     GL   +EY   V A N      PS  S+P+V       P  P + + T  T
Sbjct: 23681 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 23740

Query: 1645  PTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
              TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y  
Sbjct: 23741 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 23800

Query: 1701  SVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTE 1749
              V A        PA+  G V   E +  P             V       +TI  + K  
Sbjct: 23801 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP- 23859

Query: 1750  TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVI 1807
                 F +      GQ   +R +     ++T   ++     D   Y   L +      V I
Sbjct: 23860 ----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 23915

Query: 1808  DASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVV 1858
                  I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    + 
Sbjct: 23916 KVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTID 23974

Query: 1859  PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA------------- 1905
              R R   T   + GL+   EY   V A      S+PL   +    +              
Sbjct: 23975 SRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPE 24032

Query: 1906  -----LSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 1955
                   S  ++SW+  +D      + Y I      TD+     +   T+T  T+TGL   
Sbjct: 24033 VLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPD 24092

Query: 1956  ATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2012
             A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V  +WE
Sbjct: 24093 AEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWE 24147

Query: 2013  RMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2067
             +    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 24148 KPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24194



 Score =  117 bits (294), Expect = 9e-26
 Identities = 153/711 (21%), Positives = 271/711 (38%), Gaps = 74/711 (10%)

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
             PP   ++   I   ++ ++W PP       L+ ++V      +      +S S + +   
Sbjct: 23529 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 23587

Query: 1325  LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              T L  G EYV  V++        Y Q E    R   +     P  +   D++ +  T+ 
Sbjct: 23588 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 23646

Query: 1378  WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
             W  P     + +TGY +           R ++VP +      T LT G EY   + A+N 
Sbjct: 23647 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23706

Query: 1434  R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
             R          P++          P++  V   T TS+ ++W  P       V  Y I  
Sbjct: 23707 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 23766

Query: 1483  GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
              +   +   +  T P      T++ L  G +Y   V A    G    +  P ++     +
Sbjct: 23767 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23826

Query: 1543  DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
             + P   ++ +     I V+    +  + P+ G  + +    K G   +K       +T  
Sbjct: 23827 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 23885

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
             E+ I+           +  +N  G+    ++  V   P   +  L++  +   S+   W 
Sbjct: 23886 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23945

Query: 1654  PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
             PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A   
Sbjct: 23946 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 24002

Query: 1708  TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
                S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ ++
Sbjct: 24003 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 24062

Query: 1758  AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
                 +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  D
Sbjct: 24063 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24121

Query: 1809  ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
                    P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R  
Sbjct: 24122 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 24181

Query: 1865  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAP 1915
               + TI GL   TEY   V A      S P    ++T     ++ T   AP
Sbjct: 24182 DKQFTIGGLLEATEYEFRVFAENETGLSRP----RRTAMSIKTKLTSGEAP 24228



 Score =  116 bits (291), Expect = 2e-25
 Identities = 283/1346 (21%), Positives = 478/1346 (35%), Gaps = 213/1346 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17848

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17849 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17895

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17896 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17951

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17952 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 18011

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 18012 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18070

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18123

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 18124 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18182

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18300

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 18301 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18354

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 18355 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18414

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAV-PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 18474 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18532

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 18533 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18712

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 18713 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18760

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 18761 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18816

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 18817 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18873

Query: 1613  YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
               +N SG     V   V   P AP +L   +V   S++  W PP      ++T Y   + 
Sbjct: 18874 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 18930

Query: 1668  PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
              K +T       +  + +     +  L     Y   V A  +     PA+    V   E 
Sbjct: 18931 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 18990

Query: 1724  VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
               PP R  + D T  T TI W  K E+     ITG+ V+ +   G        +      
Sbjct: 18991 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 19048

Query: 1779  TITGLQPGTDYKIYLYTLNDNARSSP 1804
             TI+GL  G +Y   +  +N+  RS P
Sbjct: 19049 TISGLTAGEEYVFRVAAVNEKGRSDP 19074



 Score =  115 bits (289), Expect = 4e-25
 Identities = 310/1459 (21%), Positives = 503/1459 (34%), Gaps = 214/1459 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 18467 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18521

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 18522 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18579

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 18580 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18638

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 18639 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 18692

Query: 905   DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 18693 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18752

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
             L G+              VT L     Y F++ A++     +P T      AQ+  +   
Sbjct: 18753 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18801

Query: 997   --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
               LDA      V    +T+ +  T    P  ++   +    LT R Q     V  S +  
Sbjct: 18802 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 18858

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 18859 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18918

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 18919 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 19034

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
             ++ ++  +V   +    T   L+ G EY   V  V +   S P  +   +I     + P 
Sbjct: 19035 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 19091

Query: 1271  TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
              +L F               P        V +              V + + V  LSI  
Sbjct: 19092 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 19151

Query: 1319  SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
             +    V      GT  +   +S         +    + G   P  ID  +++ +S T+ W
Sbjct: 19152 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 19203

Query: 1379  IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
               P       I+ Y I    E  S          +R SI +  LT G+EY   + A N  
Sbjct: 19204 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19262

Query: 1434  -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
                   E S ++     +    P   +VV AT +++L++W  P       V  Y + Y E
Sbjct: 19263 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19322

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
                    +   +  + +   +SGL  G+ Y   VYA  + G G    S +P+    R   
Sbjct: 19323 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 19380

Query: 1543  DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
             D P Q +VT++   S+S+KW        + +TGY V           K       +T   
Sbjct: 19381 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19440

Query: 1599  IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
             +  L     Y   V+A+N       PS  + P +V+  V       D+KF  V     + 
Sbjct: 19441 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 19499

Query: 1651  QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
             +    N  + G  + V    K G   E       ++ D+ +++     +       V  L
Sbjct: 19500 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19559

Query: 1706  KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
             K+   +R        L+   PP     +   T    ++SW    E   G  +D   V   
Sbjct: 19560 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 19618

Query: 1763  GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
               + +  TI   +  + S  +T L  G +Y   +  +N      P+       +D  T  
Sbjct: 19619 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19678

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               P++L   + T  S+ + W  P     + I+GYII+  +  S     V +         
Sbjct: 19679 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19738

Query: 1870  ITGLEPGTEYTIYVIA-----LKNNQKSEPLI------------GRKKTGQEALSQTTIS 1912
              TGL  G EY   V A     L    ++ PLI             + K      +  TI+
Sbjct: 19739 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIA 19798

Query: 1913  WA-PFQDTSEYIISCHPVGTDEEPLQFRVPGTS---TSATLTGLTRGATYNIIVEAL--- 1965
             W  P  D    I          +   ++    S   T  T++GLT GA Y   V+++   
Sbjct: 19799 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 19858

Query: 1966  --------KDQQRHKVREE 1976
                      D Q  K REE
Sbjct: 19859 GASDPSDSSDPQIAKEREE 19877



 Score =  115 bits (288), Expect = 5e-25
 Identities = 283/1405 (20%), Positives = 509/1405 (36%), Gaps = 159/1405 (11%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18498 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18556

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18557 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18603

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18604 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18662

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18663 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18722

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18723 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18782

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 18783 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18842

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 18843 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18899

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 18900 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18959

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 18960 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 19016

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 19017 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19076

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 19077 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19129

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAVPPPTDL 1273
             L+E    + SS    T  ++    + +V  Y +         +VPI+  ++    PP  +
Sbjct: 19130 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 19189

Query: 1274  RFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTN 1327
             R   +  D++ ++W PP       ++N++V     K E        +S + +  ++ +  
Sbjct: 19190 RIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVR 19245

Query: 1328  LLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP 1381
             L  G+EY   V +          ES+ +          P G       T ++  V W  P
Sbjct: 19246 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19305

Query: 1382  ----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----G 1433
                  + + GY + +         + +++  +   + ++ L  G  Y   + A N    G
Sbjct: 19306 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19365

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             +              D P   EV   T  S+ + W  P       +  Y +   E     
Sbjct: 19366 KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGR 19425

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQM 1548
              ++       ++   ++ L     Y   V+A       S  S     I  + +++ P  M
Sbjct: 19426 WLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVM 19485

Query: 1549  QVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIE 1600
                  +D  +  + + L  ++ + G    V +  K+G       +T+    D  T +T++
Sbjct: 19486 MDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK 19545

Query: 1601  GL--QPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT--DLKFTQVTPTSLSAQWTPP- 1655
                 + T +YV+++  +N +G     V   V   P P    L+   +T    S  W  P 
Sbjct: 19546 DCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 19603

Query: 1656  ---NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLT 1710
                   +  Y   +  K +T  +       +   +S  V+ L+   +Y   V  +     
Sbjct: 19604 EDGGADIDYY---IVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 19660

Query: 1711  SRPAQGV-VTTLENV---SPPRRARVTDATETTITISW-RTKTE---TITGFQVDAVPAN 1762
               P + V +  L+     SPP    +T  T+ ++T+ W R +++    I+G+ ++    N
Sbjct: 19661 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19720

Query: 1763  GQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAI--- 1813
                 ++   KP  D+R  + TGL+ G +Y+  +Y  N    S P     +I A   +   
Sbjct: 19721 SLRWVRVNKKPVYDLRVKS-TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19779

Query: 1814  DAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               PS  + + +   ++ ++W  P     A ITGY ++Y+K      +   +   G TE T
Sbjct: 19780 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 19838

Query: 1870  ITGLEPGTEYTIYVIALKNNQKSEP 1894
             I+GL  G EY   V ++     S+P
Sbjct: 19839 ISGLTTGAEYVFRVKSVNKVGASDP 19863



 Score =  112 bits (281), Expect = 3e-24
 Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 14168 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14222

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 14223 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14269

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 14270 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14329

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 14330 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14389

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 14390 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14448

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 14449 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14508

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 14509 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14565

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 14566 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14624

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 14625 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14683

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 14684 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14742

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 14743 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14799

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 14800 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14859

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 14860 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14918

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 14919 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14978

Query: 1383  AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
             +     I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 14979 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 15038

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 15039 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15095

Query: 1492  QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +      +      T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 15096 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15155

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 15156 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15208

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
                  +             ++ A NP G ++ +    V   P P +  L  T+VT     
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15268

Query: 1650  AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
               W PP      ++  Y V+   K +T  +   N+A +   + + V+ L+   +Y     
Sbjct: 15269 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 15325

Query: 1699  EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
              V+ Y + + L S P   V        PP+   VT  T+ ++ + W           ++ 
Sbjct: 15326 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15384

Query: 1759  VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
             +        QR IK + ++     Y ++GL  G +Y+  +   N    S+P         
Sbjct: 15385 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 15444

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
              D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V  P 
Sbjct: 15445 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 15504

Query: 1863  P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
                 T  TITGL    EY I + A+ +    EP +
Sbjct: 15505 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15539



 Score =  110 bits (275), Expect = 2e-23
 Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)

Query: 709   NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
             N V     P  P+     S  E+T    V+SW    D   G ++   + E+ +  + + +
Sbjct: 10602 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 10655

Query: 769   PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
             P T+    T+  +  LL G+ YI      N+Y IS+      + +  +   PDAP  P V
Sbjct: 10656 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 10715

Query: 820   DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
              +V   S +V W++P     PIT Y +    ++      +            + DL  G 
Sbjct: 10716 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 10775

Query: 875   QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             QY   + A  E     P    +             P + + ++ T   V + W PP    
Sbjct: 10776 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 10835

Query: 932   -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
              S + GY V+   V +         P S   T  +VTGL  G TY F+V AV+   ES P
Sbjct: 10836 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 10895

Query: 989   LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
                 +      +L+ P  +   N      +      R  A I G    ++T     R  P
Sbjct: 10896 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 10955

Query: 1040  RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
              +   +V P  SK  +RN         SL           +  V    +PG   PP + E
Sbjct: 10956 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 11012

Query: 1098  VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
             V+E    +  +TW      G      + +  R     + +P   TS   S     L  G 
Sbjct: 11013 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 11072

Query: 1148  EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
             +Y++  +V  + Q    P V      K + PL    PP +LH   + D   +++ W   +
Sbjct: 11073 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 11129

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
             R     ITGY +       Q     + V + +   C    L  G  Y   V    ++   
Sbjct: 11130 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 11184

Query: 1257  VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
             + + DT IP       VPP  +L    I         T+R    +   P P+   T    
Sbjct: 11185 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 11241

Query: 1301  RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
               S +K +E     + + S    +   L   T EY ++VS+       +       T LD
Sbjct: 11242 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 11297

Query: 1360  ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
                 PTG I+  D+T    T+ W  P+       I +  E    R     V  S +S T 
Sbjct: 11298 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11357

Query: 1415  --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
               + +L  G EYV  + A N        + +P +   + +    P    V   T  +  +
Sbjct: 11358 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11417

Query: 1467  SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             SW  P     +    YY      TG    V +  +   K   T  GL  G  Y   V+A 
Sbjct: 11418 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 11475

Query: 1522  TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
                G S  S     I     I  P      ++ D    +  + W        SP+ GY V
Sbjct: 11476 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 11535

Query: 1575  TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
                    PG  +      D    Q    + GL    EY   + A N  GE +P  L ++ 
Sbjct: 11536 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 11592

Query: 1629  VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
             +   I  P +++   VT   +        +++   RV+  P+      K G +    K +
Sbjct: 11593 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 11650

Query: 1679  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
             +L  D   V +  +  A + +   Y +    +S  AQG  +V  L+   P +  +VT+ T
Sbjct: 11651 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11709

Query: 1737  ETTITISWRTKTET----ITGFQVD 1757
             +   TISW    +     IT F V+
Sbjct: 11710 KENCTISWENPLDNGGSEITNFIVE 11734



 Score =  110 bits (274), Expect = 2e-23
 Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
            +T++T  S +++W    D        Y +     D   +  L ST    N     L+P +
Sbjct: 7487 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 7546

Query: 785  KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
            +YI      N+Y + E  + S I +  Q   P  P       +   ++ + W  P     
Sbjct: 7547 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7606

Query: 836  APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
            +PITGY +    P  +       +P    +  +  L    +Y   + A       +  +S
Sbjct: 7607 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7666

Query: 890  TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
            T  ++ ++    P     P+ +D     V    V + WT PE    + +  Y ++++   
Sbjct: 7667 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7721

Query: 946  LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
                    + +P +++    + GL  G  Y F+V AV+   ES+P       L  ++   
Sbjct: 7722 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7778

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
               P  L+ +N T +T  ++WT P     + IT Y +     RR   +  +     +K  
Sbjct: 7779 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7838

Query: 1053 LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
            +  L   S Y   + A            ++S  A   FTT  PG   PPY   V + T  
Sbjct: 7839 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 7893

Query: 1103 -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
             + + W P    G +            LG R  + G+          +  V+ +  G E 
Sbjct: 7894 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 7949

Query: 1150 VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
             + ++   +       +  +   +    +P SPP +LH+    D G   + ++W   E++
Sbjct: 7950 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 8006

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                I GY +   P   ++   +      D      + + P  EY + V  V     S P
Sbjct: 8007 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 8066

Query: 1259 --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
              IS+ ++   P   P  DL   +I          P   R    P  S       V+ S 
Sbjct: 8067 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 8126

Query: 1305 ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
               +KN+   A L +  S  A      + L N L      ++V  +              
Sbjct: 8127 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 8172

Query: 1356 TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
             GL  P   I  SDIT +S  + W  P     G  I H+        R   +P     ++
Sbjct: 8173 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 8230

Query: 1411 NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
             S T+ +L P  EY   + A+N   G E    ++P++        D P D+EV   T  +
Sbjct: 8231 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 8290

Query: 1464 LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
            + I+W  P       +  Y   +I  GE        E  VP    T T  GL+ G +Y  
Sbjct: 8291 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 8347

Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
             V A    G S  S           ID P  +  T ++         D SIS      + 
Sbjct: 8348 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 8407

Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
            W+   + +    +    K    P   +  G  Q E                         
Sbjct: 8408 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8463

Query: 1600 -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
             + L+P    +  +  +N  G ++ P   + + T   P +  F  +  TS+  +W PP  
Sbjct: 8464 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 8522

Query: 1656 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
                ++  Y +    K K          PDS  +VV+  +   KY V+       Y  + 
Sbjct: 8523 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 8572

Query: 1708 TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
               +R   G   V   L    P      P +  V D T  ++ + W    +    I G+ 
Sbjct: 8573 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 8632

Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
            ++    N    + + +++   +++  + GL  G  Y   +   N     + SP   D  T
Sbjct: 8633 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 8690

Query: 1812 AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
            A D      P   R   T+  ++ + W+PP       I GY +  +  G+          
Sbjct: 8691 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8750

Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
              V + T+  +  G +Y + V A+    +  P
Sbjct: 8751 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 8782



 Score =  109 bits (273), Expect = 3e-23
 Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6740 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6799

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6800 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6858

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6859 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6918

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6919 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6978

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6979 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 7036

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 7037 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7095

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 7096 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7155

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 7156 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7210

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
               +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 7211 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268

Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7328

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
             VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 7329 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7382

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                  V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 7383 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7439

Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
            +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 7440 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7499

Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 7500 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7552

Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
             A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 7553 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7612

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
             V     +     +        T   ++GL    +Y   V A+N +G  +P   T    I
Sbjct: 7613 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7672

Query: 1633 PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
              P D  +    P       TS+   WT P      ++  Y + +    KTG  + + +A
Sbjct: 7673 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 7729

Query: 1682 P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
                ++  ++ GLM   +Y   V A+     S P++    V   E +   SPPR   V +
Sbjct: 7730 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7789

Query: 1735 ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
             T+ T  + W    +     IT + V+   V   G   +  T+K      T+T L  G+ 
Sbjct: 7790 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 7847

Query: 1789 YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
            Y   +   N   +S       S +  D  T    P  L  +  T   + + W+PP+
Sbjct: 7848 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 7903



 Score =  109 bits (273), Expect = 3e-23
 Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)

Query: 692   VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
             VTRFD    S    +T    +G  T F       SP    + ++ E+   S  +SW    
Sbjct: 18863 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18918

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
             +     ++ + VE     E     Y  + +  T T+  I +L  G  Y   V   +E G 
Sbjct: 18919 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975

Query: 799   QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
               L   T++      PP P    T+  V   +  ++W +P++     ITGY  V     +
Sbjct: 18976 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 19032

Query: 851   GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
             GS       +      T+S L  G +Y   + AV E   S P      VI ++    P  
Sbjct: 19033 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 19090

Query: 905   DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
              +V  P     V+  + +K+ + +     A   +R D          GQ L     ++ +
Sbjct: 19091 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 19139

Query: 960   TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
             +   VT LS        V  Y    + S G  + P+T     +   P  ++    +  ++
Sbjct: 19140 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19199

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
              + W PP      QI+ Y   V          + V  +V++  ++   L   SEY   + 
Sbjct: 19200 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19257

Query: 1068  AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
             A          ES      +    PG    P     T++T+++TW           IG+ 
Sbjct: 19258 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19317

Query: 1117  LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
             L  +        +A + + +D+  + VSGL  G+ Y   VY   +   G+   +      
Sbjct: 19318 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19376

Query: 1171  VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
               P  PP     TN+  ++        + D G     +  ER   PD  G  +    TN 
Sbjct: 19377 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 19434

Query: 1216  QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
             Q+       +  DQ       +    D++S   E +     VKDD E       V   D 
Sbjct: 19435 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 19493

Query: 1263  IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
             I+        +     G     ++WA    I++             E+ A   I  +DN 
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 19539

Query: 1323  VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
              +LT          +YV+++ +V      +   +   K G   P G ++ + +TA   ++
Sbjct: 19540 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 19597

Query: 1377  HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
              W  P+    A I  Y + +    H +    E  +     S  +T L  G EY+  +  +
Sbjct: 19598 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 19655

Query: 1432  NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
             N        E   +      TV   P  LE+ + T  S+ + W  P       +  Y I 
Sbjct: 19656 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19715

Query: 1482  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
               E      V+    P        +GL+ G +Y   VYA    G S P+ + P+ I    
Sbjct: 19716 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 19774

Query: 1541  EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
              +     PS+ ++ D    +I++ W+       +P+TGY V    K+     KT      
Sbjct: 19775 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 19833

Query: 1594  QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
              TE TI GL    EYV  V + N      PS  S P +       P     ++++ T + 
Sbjct: 19834 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 19893

Query: 1645  PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
                 S   T P      +R R  P           +T    +   +  S ++  +    +
Sbjct: 19894 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 19947

Query: 1696  TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
              KY +++   ++ L++     VV  L+   PP    V D T+ +  +SW          +
Sbjct: 19948 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 20004

Query: 1752  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
               + ++   A+ +  +  T   +  SY +T LQ G  Y   +   N+     P       
Sbjct: 20005 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 20064

Query: 1812  AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
              I      P  L   + + +S+ ++W  P     +RI  Y+++  + G   +  V     
Sbjct: 20065 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 20122

Query: 1864  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
               T   ++GL   +EY   V A      S+P
Sbjct: 20123 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20153



 Score =  108 bits (271), Expect = 4e-23
 Identities = 280/1299 (21%), Positives = 479/1299 (36%), Gaps = 170/1299 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15258 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15375

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15376 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15434

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15491

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15492 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15551

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15552 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15602

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15603 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15662

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15663 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15719

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15720 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15777

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15778 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15834

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 15835 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15888

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 15889 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15946

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 15947 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 16005

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 16006 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 16064

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 16065 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16124

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 16125 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16184

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
                   T   + GL     Y   V A+N +G  S+P   T   T     D         S
Sbjct: 16185 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 16239

Query: 1648  LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
             +  ++    V   G   +V       P+  I          +++ + +     AT   V 
Sbjct: 16240 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 16299

Query: 1702  ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
                       +   K+    R     V  L+   PP     ++  T    T++W+   + 
Sbjct: 16300 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 16359

Query: 1751  ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
                  ++ +    +T   +   +  +V+  S  +T L  G +Y   +     Y + +   
Sbjct: 16360 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 16419

Query: 1802  SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
             S PVV      + DAP        T +S++V W+ P     + I GY++ K +K G    
Sbjct: 16420 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 16479

Query: 1856  EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 R   G     +TGL    +Y   V A      SEP
Sbjct: 16480 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16517



 Score =  105 bits (261), Expect = 6e-22
 Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 9924  VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9983

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 9984  FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 10043

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 10044 TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10101

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 10102 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10161

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 10162 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10221

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 10222 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10275

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 10276 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10335

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 10336 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10395

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 10396 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10454

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 10455 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10511

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
             PPT          +R       T R +  P P +         S  K+E DV E     +
Sbjct: 10512 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10562

Query: 1315  SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
               +P+  A+          G   VV  +S   +     +    + G   P G + F ++T
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 10620

Query: 1371  ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
              +   + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+ 
Sbjct: 10621 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 10679

Query: 1427  SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
              I A N    S  L+           V D P    V   T  S L++W+ P         
Sbjct: 10680 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 10739

Query: 1472  -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
                     ++ R+ R+T        P  +F VP          L  G  Y   V A    
Sbjct: 10740 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 10787

Query: 1523  GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
             G GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY + 
Sbjct: 10788 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 10844

Query: 1576  TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
                K G    +     P+   +T+  + GL+    Y   V A N +GES P        +
Sbjct: 10845 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 10898

Query: 1633  PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
             P P  +K     P   L A          G  +R++      P  K    KE   AP  +
Sbjct: 10899 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10958

Query: 1686  SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
              + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR   V++ 
Sbjct: 10959 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 11016

Query: 1736  TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
              + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    L  G  Y
Sbjct: 11017 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 11074

Query: 1790  KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
                +   N   R   V        +D       P +L  +      + + W  P     +
Sbjct: 11075 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 11134

Query: 1839  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
              ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K+E ++G
Sbjct: 11135 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 11184



 Score =  103 bits (257), Expect = 2e-21
 Identities = 257/1326 (19%), Positives = 466/1326 (35%), Gaps = 204/1326 (15%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 13067 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 13126

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 13127 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 13184

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 13185 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13243

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 13244 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13303

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 13304 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13363

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 13364 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13416

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 13417 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13474

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 13475 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13529

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPAVPPPTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 13530 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13585

Query: 1274  RFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
             +  ++   +  + W  P S     +  ++V +   +N+      S+S   +A  LT    
Sbjct: 13586 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE--- 13642

Query: 1331  GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI----T 1386
             G EY   VS+  E  E TP            T +   D+ A    +  +     +    +
Sbjct: 13643 GKEYTFRVSAENENGEGTP---------SEITVVARDDVVAPDLDLKGLPDLCYLAKENS 13693

Query: 1387  GYRIR-----HHPEHFSGRPRED------RVPHSRNSITLTNL------TPGTEYVVSIV 1429
              +R++           S +  ED      RV    +++  T +      +   +Y +++ 
Sbjct: 13694 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 13753

Query: 1430  ALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1485
              + G +E  + I            ++    T  ++ + W  P       +  Y +   ++
Sbjct: 13754 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13813

Query: 1486  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTEI-D 1543
               N  V   +    K+T  ++ L  G++YT  V A    G      S+PI   +  ++ D
Sbjct: 13814 VNNKWVTCASAV-QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13872

Query: 1544  KPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1599
              P    + DV+ +S+S+ W        SP+TGY +    +N     +         +  +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
              GL   +EY   V A N +G  +P + +    A+  I  P   +   +T  S++  WT P
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP 13992

Query: 1656  NV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL-- 1709
                   +LTGY V          MK  ++     +  V+ L+   KYE  + A K+T   
Sbjct: 13993 KYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRA-KNTAGA 14051

Query: 1710  TSRPAQGVVTTLEN---------VSPPRRARVTDATETTITI-------------SWRTK 1747
              S P++   T +           + P  +  +T     TI +             SW   
Sbjct: 14052 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 14111

Query: 1748  TETITGF---QVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYLYTLNDNARSS 1803
              + I      Q+ + P +    I+   + D   YTIT   P GT  +    T+ D     
Sbjct: 14112 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLD----- 14166

Query: 1804  PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1859
                         P  +     +     ++W PP     + I  YI++  +       VV 
Sbjct: 14167 --------VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS 14218

Query: 1860  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG----------------RKKTGQ 1903
                        T L  G EY   V A+ +  K EP+                  + +   
Sbjct: 14219 EDIQSCRHVA-TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSN 14277

Query: 1904  EALSQTTISWA-PFQDTSEYIISCHPVGTDEEPLQF----RVPGTSTSATLTGLTRGATY 1958
                +  T+SW  P  D    I   H    +++ L++    + P +     +TGL  G+TY
Sbjct: 14278 VTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTY 14337

Query: 1959  NIIVEA 1964
                V A
Sbjct: 14338 EFRVSA 14343



 Score =  102 bits (255), Expect = 3e-21
 Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10330 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10388

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10389 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10436

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10437 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10496

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10497 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10557 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10614

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10615 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10670

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10671 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10730

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10731 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10790

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 10791 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10848

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 10849 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10908

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 10909 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10967

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 10968 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 11013

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 11014 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11072

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 11073 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11131

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 11132 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11189

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 11190 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11241

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 11242 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11293

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 11294 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11350

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T        + P+P      T +
Sbjct: 11351 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11410

Query: 1644  TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
             T  + +  WT P       +TGY +    +E TG    +N  P +     V+GL     Y
Sbjct: 11411 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 11468

Query: 1699  EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
             E  V+A      S+P+           ++   PP   ++ D +  T  + W TK      
Sbjct: 11469 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 11527

Query: 1749  ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
               I G+ V+     G     R  K ++    ++ + GL  G +Y+  +   N      P
Sbjct: 11528 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11585



 Score =  101 bits (252), Expect = 7e-21
 Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21861 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21919

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21920 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21967

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21968 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 22027

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 22028 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22087

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 22088 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22146

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 22147 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22202

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22203 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22261

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22262 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22319

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22320 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22374

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22375 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22434

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22435 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22494

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 22495 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22551

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 22552 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22610

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22668

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 22669 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22726

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 22727 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22786

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 22787 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22843

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 22844 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22891

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
             + YVV+           V A N  G     ES+P+V     TIP+P  +     T    +
Sbjct: 22892 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22951

Query: 1649  SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
               QWT P      +++ Y V    K +   ++   +  D     + + V+ LM    Y+ 
Sbjct: 22952 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 23008

Query: 1701  SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
              V A+     S P  A   ++  E      PP   RV D T+ +I+++W
Sbjct: 23009 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 23057



 Score =  101 bits (251), Expect = 9e-21
 Identities = 274/1343 (20%), Positives = 479/1343 (35%), Gaps = 185/1343 (13%)

Query: 692   VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
             V R+D   +T T  ++  T +         +P    +  VTEIT  S  ++W    +   
Sbjct: 16698 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 16757

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
               +  + VE     E     Y  + +     S  I  L  G  Y   V   +E G     
Sbjct: 16758 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 16814

Query: 803   LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
              +       + P  P   TVD V   S+ + W++P+       I Y   ++   +E    
Sbjct: 16815 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 16873

Query: 860   ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
             E A        +++L  G +Y   + AV E   S P           +VI+ +      S
Sbjct: 16874 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16933

Query: 905   DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
              +V   +DL+ +EV      K TI WT           D +P+       Q   I+    
Sbjct: 16934 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 16976

Query: 962   AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
              ++T LS   T+      Y    A   G+++  +      K D P   ++F + +  ++ 
Sbjct: 16977 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 17036

Query: 1015  VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
             + W PP      QIT Y +    T        +   + +   +  L+  +EY   + A  
Sbjct: 17037 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 17096

Query: 1071  --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
               G     ES      +   +PG    P+ T +++ ++VI W        +P IG+ L  
Sbjct: 17097 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 17156

Query: 1120  RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
             +        +  + +  D+       L  G+EY + +       V +  +  +  +    
Sbjct: 17157 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 17215

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
               P   P  + ++ N     +T+ W +        ITGY +     P       S   V+
Sbjct: 17216 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17271

Query: 1226  HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
                ++  T   L+    Y   V          K    + PI+   +  +P +   P   D
Sbjct: 17272 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 17328

Query: 1273  LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
                 N G +T R    V   P P+I+           K  E+ A   I  +D   +L   
Sbjct: 17329 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 17381

Query: 1326  -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
                 + G +Y++  S+V    +S P+  +       P G +  + +T+   ++ W +P  
Sbjct: 17382 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 17439

Query: 1384  TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALN------G 1433
                G  I H+   +  + R     V      NS+ +T L  G EYV  I+A+N       
Sbjct: 17440 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17499

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
              E +P+L+     +   P+ LEV      S+ + W+ P        I Y  E    S ++
Sbjct: 17500 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 17559

Query: 1493  EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
                    + T     ++GL    +Y   V A    G    S  P ++ Y+      +   
Sbjct: 17560 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 17617

Query: 1545  PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN-GPGPTKTKTAGPDQTEMTI 1599
             P+   + D   NSI++ W        S + GY V     +       T   G   T   I
Sbjct: 17618 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 17677

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
               L    EY + V A N  G  +    T+V     P D    +     L ++     V  
Sbjct: 17678 SKLTEHQEYKIRVCALNKVGLGE---ATSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 17732

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
              G   R+    K  P  EI  + +    +  V +   +  T+  +           +  L
Sbjct: 17733 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 17792

Query: 1706  KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
             +++  S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +
Sbjct: 17793 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 17852

Query: 1762  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
               +     + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS   
Sbjct: 17853 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 17912

Query: 1818  NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1873
              +     +  S  + W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL
Sbjct: 17913 KVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGL 17970

Query: 1874  EPGTEYTIYVIALKNNQKSEPLI 1896
               G EY   V A     KS+P +
Sbjct: 17971 SSGQEYQFRVKAYNEKGKSDPRV 17993



 Score =  100 bits (250), Expect = 1e-20
 Identities = 283/1422 (19%), Positives = 504/1422 (35%), Gaps = 178/1422 (12%)

Query: 609   SGPVEVFITETPSQPNSHPI-----------QWNAPQPS---HISKYILRWRPKNSVGRW 654
             S P E  +   P  P   P+           +W  P+ +    I+ YI+  R   + GRW
Sbjct: 15040 SKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPN-GRW 15098

Query: 655   KEATIPGHL-NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
              +A     L N +T+ GL     YE ++I+    G           +  S P  S+ +T 
Sbjct: 15099 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG---------AISPPSEP--SDAITC 15147

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ---YLDLPS 770
                  +P +       +        ++   +D         E S++G E +    L++  
Sbjct: 15148 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15207

Query: 771   TATSVNIPDLLPGRKY--IVNVYQISEDGEQSLILSTSQTTAPDAPPDP-TVDQVDDTSI 827
                S N+ +    R+      +   +  G    I +      P  P  P  V +V     
Sbjct: 15208 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKC 15267

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             V+ W  P     A I  Y +    +   + T +        + ++ L  G +Y   + AV
Sbjct: 15268 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15327

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              +     P+  +      P     P P++ +   +T   + + W  P+S      ++ I 
Sbjct: 15328 NKYGVGEPLESEPVLAVNPYGPPDP-PKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI- 15385

Query: 944   VNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYFKVFAVSHGRESKPL-------TA 991
             V    + GQR +  ++ T  +    V+GL+ G  Y F++ A +    S P          
Sbjct: 15386 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15445

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYN--VG 1045
                 K   P N + ++ + S++ + W  P     ++ITGY + + L    + +      G
Sbjct: 15446 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG 15505

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
                + Y +  L    EY + + A+        A    T       +PP      +   V+
Sbjct: 15506 LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVV 15565

Query: 1106  T--------------WTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
             T                PAP + +      S   +A  E TS    ++V  +       Y
Sbjct: 15566 TIRACCTLRLFVPIKGRPAPEVKWARDHGESLD-KASIESTSSYTLLIVGNVNRFDSGKY 15624

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRI 1208
              + V      + A +  +V+    PP +L ++    T V T++W+         I  Y +
Sbjct: 15625 ILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV-TLTWDPPLLDGGSKIKNYIV 15683

Query: 1209  TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPIS 1260
                 +  +  +++    H  ++S   D L  G  Y   V    +          ESV  S
Sbjct: 15684 EKRESTRKAYSTVATNCH--KTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 15741

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSIS 1317
             +  +P    P  +   ++  +++ ++W  P       +  ++V      +++     ++ 
Sbjct: 15742 ERPLP----PGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVK 15797

Query: 1318  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              ++    +T L+ G EY   VS+  E+  S P +                 +  N+FTV 
Sbjct: 15798 VTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV- 15854

Query: 1378  WIAPRATITGYRIRHHPEHFSGRP------REDRVP----------HSRNSITLTNLTPG 1421
                    + G  ++     F GRP       +D VP           + N+  LT     
Sbjct: 15855 -------LAGEDLKVDVP-FIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDAC 15906

Query: 1422  TE----YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV---- 1473
              E    YVV +    G     L +            +++   T  S+ +SW  P      
Sbjct: 15907 REDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGS 15966

Query: 1474  TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP-ASSK 1532
             ++  Y +   +T   +  Q  +   +++T     LK G +Y   + A    G S   +S+
Sbjct: 15967 SINNYIVEKRDTS-TTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 16025

Query: 1533  PISINYRTEIDKPSQMQVTDVQD-NSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKT 1587
             P    Y  ++  P    V  +   +S+ V+W        S V GY +    +N     K 
Sbjct: 16026 PTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKL 16085

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL----KFTQV 1643
                   QT+    GL+  VEY   V A+N  G  +P   +       P D     +   V
Sbjct: 16086 NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV 16145

Query: 1644  TPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699
             T  S++ QW  P      ++TGY V      +   MK        +   V+GL+   +YE
Sbjct: 16146 TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYE 16205

Query: 1700  VSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
               V A     + S P++  G +T  + V PPR +      +T +  +  +       F+V
Sbjct: 16206 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES-------FKV 16258

Query: 1757  DAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SSPVVIDASTAI 1813
             DA       P  + IK D        L+   TD+   L ++ D  R  S   ++ A    
Sbjct: 16259 DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSGNYILKAKNVA 16317

Query: 1814  DAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSP 1853
                S   N++ L               T     ++W+PP     + I  YI++  +    
Sbjct: 16318 GERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRL 16377

Query: 1854  PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
                VV           +T L  G EYT  ++A+      EPL
Sbjct: 16378 VWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 16418



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 336/1557 (21%), Positives = 550/1557 (35%), Gaps = 260/1557 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 9993  GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 10047

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 10048 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 10103

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 10104 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 10151

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 10152 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10209

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 10210 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10266

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 10267 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10319

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 10320 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10378

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 10379 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10438

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKGNQESP 1076
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G Q  P
Sbjct: 10439 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG-QGKP 10497

Query: 1077  KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT---- 1132
                    T +   + P  + +  +   +       R+G    +     G+   +V+    
Sbjct: 10498 SFCTKPITCKDELAPPTLHLDFRDKLTI-------RVGEAFALTGRYSGKPKPKVSWFKD 10550

Query: 1133  ------SDSGSIVVSGLTPGVEYV---------YTIQVLRDGQERDAPIVNKVVTPLSPP 1177
                    D   I  +  T  +E +         Y + V      R       VV    PP
Sbjct: 10551 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPP 10610

Query: 1178  TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS---LEEVVHADQSSCTF 1234
                          + +SW+     D  G +IT      ++      +     + +++C  
Sbjct: 10611 VGPVSFDEVTKDYMVISWKPPL--DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKV 10668

Query: 1235  DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VPPPTDLRF-TNIGPDTMRVTWA 1288
               L  G +Y   ++       S P+    + A     VP   D    T +  D+  VTW 
Sbjct: 10669 SKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWN 10728

Query: 1289  PPPS--IDLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE- 1343
              P      +TN+++  R +  K    V +  I P     V  +LL G +Y   VS+  E 
Sbjct: 10729 KPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRV-PDLLEGCQYEFRVSAENEI 10787

Query: 1344  -----QHESTPLRGRQKTGLDSP-TGIDFSDITANSFTVHWIAPR----ATITGYRIRHH 1393
                     S P+  +      SP    +  D T NS  + W  PR    + I GY + + 
Sbjct: 10788 GIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQ 10847

Query: 1394  PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGREES-------PLLIGQQ 1444
                     R +  P S       +T L  G  Y   ++A+N   ES       P+L+  +
Sbjct: 10848 KVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDR 10907

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVT--VRYYRITYGETGGNSPVQ---EFTVPGS 1499
                 ++  D  +       +  +    A+   V + ++T+ +   ++P +   + T  GS
Sbjct: 10908 LEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10967

Query: 1500  KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDN 1556
             K     +  + G  Y++TV       ++PA SK +S+     +DKP     ++V++++ +
Sbjct: 10968 KLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLV-LDKPGPPRDLEVSEIRKD 11019

Query: 1557  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             S  + W        S +T Y V          +        ++    + L    +Y+  V
Sbjct: 11020 SCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFA-KHLNEGNQYLFRV 11078

Query: 1613  YAQNPSGESQPLVQTAVTTIPA---------PTDLKFTQVTPTSLSAQWTPPNVQ----L 1659
              A+N  G   P V+T    I A         P DL    V  T +S  W  P+      +
Sbjct: 11079 AAENQYGRG-PFVETP-KPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPI 11136

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1717
             TGY V     ++ G    I     ++   VV+GL     Y   V A        P   + 
Sbjct: 11137 TGYLVEY---QEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 11193

Query: 1718  VTTLENVSPPRRARVTDATE-------TTI------------TISWRT---KTETITGFQ 1755
             +   E + PP         E       TT+            T  W T   + +T   + 
Sbjct: 11194 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11253

Query: 1756  VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1815
             V+    +    I+  ++ D   Y IT                 NA  S  V    T +D 
Sbjct: 11254 VETDNFSSVLTIKNCLRRDTGEYQITV---------------SNAAGSKTVAVHLTVLDV 11298

Query: 1816  PSN----LRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
             P      +  L  TP  + +SWQPP+    + +  YI++ +        VV       T+
Sbjct: 11299 PGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV-SSGSSKTK 11357

Query: 1868  ATITGLEPGTEYTIYV-----IALKNNQKSEPLIGRKK------TGQEALSQ-----TTI 1911
               I  L+ G EY   V     I +     S P + + K       G+  ++       T+
Sbjct: 11358 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11417

Query: 1912  SWA-PFQDTSEYIISCHPVGTDEEPLQFRV---PGTSTSATLTGLTRGATYNIIVEA 1964
             SW  P  D    I   +    +      RV   P       +TGL  G TY   V A
Sbjct: 11418 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFA 11474



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 18973 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 19030

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 19031 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19081

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 19082 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19138

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 19139 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19195

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 19196 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19255

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 19256 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19309

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 19310 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19368

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 19369 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19426

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 19427 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19477

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 19478 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19534

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 19535 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19593

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 19594 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19651

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 19652 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19711

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 19712 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19770

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 19771 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19828

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 19829 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19884

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19940

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 19941 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19995

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 19996 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 20054

Query: 1621  SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
               P        +T  P+P + L  T ++  S+S  W  P      ++  Y V    K + 
Sbjct: 20055 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20114

Query: 1673  GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
               +K       S+  VVSGL   ++Y   V+A      S P + ++  L  E + PP   
Sbjct: 20115 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 20172

Query: 1729  ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
                        R     +  I IS +              +    F  +    N    ++
Sbjct: 20173 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 20232

Query: 1769  RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
              ++  D   Y IT        K ++         + VV+D       P  +  +  T  S
Sbjct: 20233 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 20281

Query: 1829  LLVSWQPPR----ARITGYII 1845
             + + W+PP+    +++T YI+
Sbjct: 20282 VTLKWEPPKYDGGSQVTNYIL 20302



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 316/1532 (20%), Positives = 551/1532 (35%), Gaps = 236/1532 (15%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 22232 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22290

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 22291 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22346

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 22347 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22398

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 22399 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22456

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 22457 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22516

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 22517 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22570

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 22571 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22629

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 22630 AQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22687

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 22688 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22743

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 22744 DARLHGDLVTIRAGSDLV--------LDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22795

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 22796 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22854

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS---SCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+   +    S     L    EY   V  V
Sbjct: 22855 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22912

Query: 1251  KDDKESVPISDTIIPA-----VPPPTDL-RFTNIGPDTMRVTWAPPPSI---DLTNFLV- 1300
                   VP+    I A     +P P  +      G + + + W  P S    +++N+LV 
Sbjct: 22913 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22972

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 22973 KREKKSLRWTRVNKDYVVY-------DTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 23025

Query: 1354  QKTGLDSPTGID-------FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                    P+            D T +S ++ W  P       I GY +    +      R
Sbjct: 23026 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 23085

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 23086 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 23144

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 23145 DDLKKTVTIRAGASL------RLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23197

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 23198 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23256

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 23257 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23315

Query: 1622  QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
             +P   +    V+ +P  P  L+   VT ++++  W  P      +LTGY +         
Sbjct: 23316 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23375

Query: 1674  PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
              MK + L P      V+ L    +Y        E  V   ++T+T+   Q   V+ T++ 
Sbjct: 23376 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 23435

Query: 1724  VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
              + P++     A    E  I I+ R        F    +  + +  ++   K    +   
Sbjct: 23436 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 23495

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
             T ++   +Y + L  +      +  VI           ++       S+ +SW+PP    
Sbjct: 23496 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 23555

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA-----LKNN 1889
              A ++GY+++      P    V      VT +T   T L  G EY   V A     + + 
Sbjct: 23556 GAPLSGYVVEQRDAHRPGWLPVSE---SVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23612

Query: 1890  QKSEPLIGRKKTGQEALSQT-----------TISWAPFQD-----TSEYIISCHPVGTDE 1933
              +SE +  R         +T           T++W P +D      + YI+    V  D 
Sbjct: 23613 LQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 23672

Query: 1934  EPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                  +VP T T    TGLT G  Y   V A+
Sbjct: 23673 WVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAI 23704



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
             T  +VT L  G  Y F+V  V+     +PL +     LD       PT+L+  + T  ++
Sbjct: 19635 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19694

Query: 1014  LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
              + W+ P +    +I+GY +     RR +     V   V+K P+ +L+  S         
Sbjct: 19695 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 19748

Query: 1061  EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
             EY V      G    ++ SP          P     P   +  +TTI I W        A
Sbjct: 19749 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 19808

Query: 1111  PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
             P  G+ +  + S   +    + S  G+   +SGLT G EYV+ ++ +      D  +   
Sbjct: 19809 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19868

Query: 1165  PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
             P + K      P  ++  E      V       +TV +     P++    + + P    +
Sbjct: 19869 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 19923

Query: 1218  GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
               +  +   + ++S T +N +     +Y +++  V     S+ +   ++    PPT++  
Sbjct: 19924 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 19981

Query: 1276  TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
              ++  ++  ++W  P +          +PVKN      E   +  +S ++N    +  +T
Sbjct: 19982 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 20034

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
             NL  G  Y   VS   E     P   ++   +      P  +  + I+ +S ++ W+ P 
Sbjct: 20035 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 20094

Query: 1383  ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
                 G RI H+      + +++ V  +    T   ++ L   +EY   + A N    S  
Sbjct: 20095 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20153

Query: 1438  -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
                  P+LI +Q    ++     P     V A      +  D P       ++T    G 
Sbjct: 20154 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 20210

Query: 1488  N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                    F    +    TI+ LK  V      Y +T    S  +   I+I     +D+P 
Sbjct: 20211 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 20266

Query: 1547  Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
                  + ++D+ + S+++KW P      S VT Y +     +    T+  +A   +T M 
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 20325

Query: 1599  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
             +  L    EY   + A+N  G S  +    VT     T P P    + T VT  S++  W
Sbjct: 20326 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 20385

Query: 1653  TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
               P       + GY + +  +      K   L   ++   V+ +     YE  VYA    
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 20445

Query: 1709  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
                +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V+   +P
Sbjct: 20446 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 20505

Query: 1761  ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
                 T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T ID+
Sbjct: 20506 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 20561



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)

Query: 730  EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
            +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 7193 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7251

Query: 786  YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
            Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 7252 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7311

Query: 836  APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
            + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 7312 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7371

Query: 896  QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
            +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 7372 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7431

Query: 949  EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
               + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 7432 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7490

Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
            T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 7491 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7550

Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
             + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 7551 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7610

Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
            G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 7611 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7669

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
              +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 7670 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7726

Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
               +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 7727 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7786

Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
              NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 7787 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7845

Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
            + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7905

Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 7906 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7965

Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
             P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 7966 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 8013

Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 8014 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8069

Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 8070 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8129

Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
            M  + +   +E   SV A         +N  G +   +   V  +P P  D+K + +T +
Sbjct: 8130 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8189

Query: 1647 SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
            S    W PP     T     V  + + G    I +    +  S  V  L+   +Y   V 
Sbjct: 8190 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8249

Query: 1704 ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
            A+     ++   G    L+N            PP    V + T   +TI+W+        
Sbjct: 8250 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 8304

Query: 1750 TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
             I G+ ++ + A G+   +R  +    + +YT  GL+ G +Y+  +       +++ +R+
Sbjct: 8305 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 8363

Query: 1803 SPVVIDASTAIDAP 1816
            +P    A   IDAP
Sbjct: 8364 TPPT-KAVDPIDAP 8376



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 272/1303 (20%), Positives = 467/1303 (35%), Gaps = 174/1303 (13%)

Query: 773   TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  +  LL G +YI     VN Y + E  E   I +    T P  P    +  V   S+
Sbjct: 19635 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19694

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
              + WSRP++     I+GY I            +N  P     V  + L+ G +Y   +YA
Sbjct: 19695 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 19754

Query: 883   VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
                 + +  + +  ET+   R++    +PSP    + V+     +TI W  P     + +
Sbjct: 19755 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 19810

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
             TGY V+    +   +    +   R T   ++GL+ G  Y F+V +V+    S P  +   
Sbjct: 19811 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 19869

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
             Q   + +        +E   T++V+         G   T+ +  RG+P            
Sbjct: 19870 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 19921

Query: 1040  ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                R Y V  + S+  L     N   + +YT+++  +           V  T  P ++I 
Sbjct: 19922 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 19980

Query: 1093  PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
                 +VT+ + V++W        AP   + +  R +   +A   VT++    S  V+ L 
Sbjct: 19981 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 20037

Query: 1145  PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
              G  Y + +    +   G   +     K+    SPP  L + +     V +++W   E  
Sbjct: 20038 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 20096

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                 I  Y +        Q N ++  V A  +      L    EY   V+       S P
Sbjct: 20097 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20153

Query: 1259  ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
               + ++P +      PP  D++  N    T+ V       +D+         V    D  
Sbjct: 20154 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 20210

Query: 1313  ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
              L  +   N  +   NL    +  V+  +   +  +    G  K  ++         PTG
Sbjct: 20211 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 20270

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              +  SDIT  S T+ W  P+    + +T Y +    E  +    E     +R  + +  L
Sbjct: 20271 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 20329

Query: 1419  TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             T G EY   I A N        + + + +    T    P    V   T  S+ + W  P 
Sbjct: 20330 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 20389

Query: 1473  VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
                   V  Y +   +       +   +    +   ++ +  G+ Y   VYA    G   
Sbjct: 20390 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 20449

Query: 1529  ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
              S     +      + P  +++TD+  NS+S+ W        S +TGY V          
Sbjct: 20450 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 20509

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ----TAVTTIPAPT--- 1636
             TK       +T+  I GL    +Y   V+A+N  G  S P       T + +   P    
Sbjct: 20510 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20569

Query: 1637  DLKFTQV------TPTSLSAQWT-PPNVQLTGYRVRVTPKE-KTGPMKEINLAPDSSSVV 1688
              L++T+V      T   L A  +  P   +  Y+     KE +T  +  +    D +S++
Sbjct: 20570 PLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYK---DDKELQTNALVCVENTTDLASIL 20626

Query: 1689  VSGLMVATKYEVSVYALK--DTLTSRPAQGVVTTLENVSPPRRA-RVTDATETTITISWR 1745
             +     A +     Y LK  + + S  A   V  L+   PP         T   IT+ WR
Sbjct: 20627 IKD---ADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWR 20683

Query: 1746  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
                +     IT + V+    +       +   +    T T +  G +Y   +  +N    
Sbjct: 20684 PPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 20743

Query: 1802  SSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPG 1851
               P+  D+  A +A      P        T NS+ V W  P A     I+GY ++     
Sbjct: 20744 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 20803

Query: 1852  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTI 1911
             S     V +     T   +TGL   ++Y   V A+               GQ        
Sbjct: 20804 SLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVN------------AAGQ-------- 20843

Query: 1912  SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 1954
                PF + SE+  +  P+     P + R+  ++ S+   G ++
Sbjct: 20844 --GPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSK 20884



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12395 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12452

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12453 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12500

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12501 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12560

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12561 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12620

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12621 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12680

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12681 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12732

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12733 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12792

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12793 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12850

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 12851 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12908

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 12909 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12966

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 12967 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 13026

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 13027 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13071

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 13072 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 13129

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 13130 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 13189

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 13190 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13249

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 13250 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13304

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 13305 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13363

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 13364 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13420

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 13421 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13478

Query: 1630  TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
                P  P ++   +++  S    W PP +     +  Y V+    E+      +      
Sbjct: 13479 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 13537

Query: 1685  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
             +S  V+ L     Y   V+A  +     P +    V   +   P    +V   ++++ +I
Sbjct: 13538 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 13597

Query: 1743  SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
              W+         I G+ VD +    +   QR +K     Y+   L  G +Y   +   N+
Sbjct: 13598 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 13655

Query: 1799  NARSSP--VVIDASTAIDAP 1816
             N   +P  + + A   + AP
Sbjct: 13656 NGEGTPSEITVVARDDVVAP 13675



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 271/1284 (21%), Positives = 458/1284 (35%), Gaps = 188/1284 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 21115 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21174

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 21175 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21233

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 21234 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21288

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 21289 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21346

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 21347 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21406

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 21407 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21466

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 21467 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21526

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 21527 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21584

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 21585 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 21640 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21694

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 21695 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21751

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 21752 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21809

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 21810 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21869

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 21870 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21917

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++    P+ ++VTD    ++S++W        
Sbjct: 21918 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21977

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 21978 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 22037

Query: 1627  T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
             T    AV  + AP    D  F Q       A     +++L   Y+ R TP    + P   
Sbjct: 22038 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 22092

Query: 1678  INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
             ++L  D  ++   S L V       A KY ++V   ++   S+     V  L+   PP  
Sbjct: 22093 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 22149

Query: 1730  ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
                 D T  + T+ W          I  + V+   A+ ++    + K   + + +  L  
Sbjct: 22150 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 22209

Query: 1786  GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
             G  Y   +  +N+         P  I A+     P  L  + T+ +S +++W  P     
Sbjct: 22210 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 22269

Query: 1838  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
             +RITGY+++  + GS     V          T+  L   TEY   V A  +   SEP   
Sbjct: 22270 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP--- 22324

Query: 1898  RKKTGQEALSQTTISWAPFQDTSE 1921
                  +EA S   I     + T++
Sbjct: 22325 -----REAFSSVIIKEPQIEPTAD 22343



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)

Query: 710  TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
            TV+   TP  P+    E   +I  +S +  W    D      + Y L ++     + +++
Sbjct: 8490 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 8546

Query: 767  DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
             + ST      ++  L+ G++Y+  V   +  G         +++      PDAP  P V
Sbjct: 8547 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8606

Query: 820  DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
            + V   S++V+W+ P+   +PI GY   +    E +ST  +    +    L     G+  
Sbjct: 8607 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 8663

Query: 877  NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
             +T ++ V     + P      +      D +  P P   +  + +   + + W PP   
Sbjct: 8664 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 8723

Query: 932  --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
                + GY VD  ++  N      +++  + + T  E+     G  Y  +V AV+   E 
Sbjct: 8724 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 8780

Query: 987  KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
             P   Q  T          +LD             T+ +             WT    ++
Sbjct: 8781 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 8840

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
               R+ +           NVG     + K  LR  +    Y ++     G++ +     V
Sbjct: 8841 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 8888

Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
            F    P   + P  T       ++ W+       +   GF +  + ++     + + ++ 
Sbjct: 8889 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 8946

Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
                ++GL  G EY +  +V+   +    P V       V PL PPT+     + E    
Sbjct: 8947 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 9004

Query: 1188 TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
            T  +T+ W+   +     I GY I     +      + + +    +S   +NL     Y 
Sbjct: 9005 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 9061

Query: 1245 VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
              V  V +  ES   +P++  I     PPT     ++  DT++V    P  I  D+T   
Sbjct: 9062 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 9121

Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
            +        E V E    P+D   +    +  +E    +S   +V E   +  +    + 
Sbjct: 9122 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 9178

Query: 1357 GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
            G                P  +  +DI A S  + W AP     G  I H+   +  + R 
Sbjct: 9179 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 9237

Query: 1402 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
            + +    +  ++     +  L P  +Y   + A+N    S      +  + D       P
Sbjct: 9238 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 9297

Query: 1452 RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
               +V+A T  S+L+SW  P       +  Y +   E G         +P+ +  + G +
Sbjct: 9298 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 9357

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
                +  L  GV Y     A+   G  P S  S P ++ +       PS  +V D   +S
Sbjct: 9358 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 9415

Query: 1558 ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
            IS+ W P +    SP+ GY V    +   G T  K    PD+   T E + P ++    Y
Sbjct: 9416 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 9472

Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
               V A N +GES+P   T    IPA TD++        + AQ     V   G ++R+  
Sbjct: 9473 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 9527

Query: 1667 ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
                  TPK   E  G  K              ++  A +SS +++     +   + S+ 
Sbjct: 9528 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 9587

Query: 1704 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
            A K+    + A   V  ++   PP+  +V+D T  +  +SW+   +     I G+ ++  
Sbjct: 9588 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 9646

Query: 1760 PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
              +G+   +  + PD  S T  +  L     Y   +   N      PV  I  +TA D  
Sbjct: 9647 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 9704

Query: 1816 -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
                 P  L+    T N++ +SW+PP+    + +T YI++   ++  G+         + 
Sbjct: 9705 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 9764

Query: 1864 GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
             V E   T+  L  G EY   V A+     S+P
Sbjct: 9765 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9797



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1521 (20%), Positives = 534/1521 (35%), Gaps = 198/1521 (13%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+      P++       P ++ + +     NS  + W  P+    S I +YI+  +
Sbjct: 16808 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 16865

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K+S  +W E      L +  I  L  G  Y  +++++ + G  +         S + P+
Sbjct: 16866 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 16916

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E        + S  V +       +S      T++  +    L +        
Sbjct: 16917 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 16975

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
              L  T  S+       G +Y + V  +   G+++  +       PD P  P   D V   
Sbjct: 16976 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 17033

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
             SI + W+ P       IT Y +    +       ++      ++ ++ L+ G +Y   I+
Sbjct: 17034 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 17093

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
             A  EN+      ++ +          P P    F   ++   + I W  P     S V G
Sbjct: 17094 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 17151

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
             Y ++    N          I  +T  +   L  G+ Y F+V+A   V  G+ SK      
Sbjct: 17152 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 17211

Query: 994   TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
                  D P   + +    + + ++WT P     + ITGY +       G+  + +    +
Sbjct: 17212 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17271

Query: 1049  -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
              +++ +  L     Y   ++A    G    P  +TG  T       P  S+ P   +  +
Sbjct: 17272 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 17328

Query: 1101  TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             T +V           +   P P I +  G +   +      + T     ++V        
Sbjct: 17329 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17388

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
               Y ++       +  P+  KV+    PP          +   +++W    +    DI+ 
Sbjct: 17389 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 17448

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
             Y +    T+      +   V  +    T   L  G EY      V+ Y V +  ES P+ 
Sbjct: 17449 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17506

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
               +  ++P   PP  L  TNI  D+M V W  P S   +  +      ++   +  +  +
Sbjct: 17507 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 17564

Query: 1318  P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
                 +D  + +T L    EY   VS  +     E +P     K          PT     
Sbjct: 17565 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 17624

Query: 1368  DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
             D T NS T+ W  P     + I GY +    E       E ++   +  + +T      L
Sbjct: 17625 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 17680

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
             T   EY + + ALN      + +G+ ++V    +  + + A P   L S     + VR  
Sbjct: 17681 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 17734

Query: 1477  -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
                RI     G  +P   ++    + T  +  ++ GV+YT              Y +   
Sbjct: 17735 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 17793

Query: 1525  GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
               S + S  +++        P  + V +V+ +S  + W P      + V  Y +      
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 17853

Query: 1581  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
                     ++   +T   +E L     Y   V A+N  G   P+     V+ A    P P
Sbjct: 17854 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 17911

Query: 1636  TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
               +  T V+ TS S  W  P      ++ GY V + PK  EK   + E  +     + VV
Sbjct: 17912 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 17967

Query: 1690  SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
             +GL    +Y+  V A  +   S P   GV      +T   ++  P       A E     
Sbjct: 17968 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 18027

Query: 1738  ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
                       ISW    E +   T   V+    +    I+   K D   YT+T       
Sbjct: 18028 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 18086

Query: 1789  YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
                   T  +N   S +V++       P  +RF   + + +++SW+PP      +I+ YI
Sbjct: 18087 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 18136

Query: 1845  IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR------ 1898
             ++     +    +V       T   IT L+ GTEY   + A     KS PL  +      
Sbjct: 18137 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQY 18195

Query: 1899  --KKTGQE--------ALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQF----RVPGT 1943
               K+ G          +  Q  + W  P  D    II  H    ++  + +    + P  
Sbjct: 18196 PFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 18255

Query: 1944  STSATLTGLTRGATYNIIVEA 1964
              T    TGL  G  Y   V A
Sbjct: 18256 DTKFKTTGLDEGLEYEFKVSA 18276



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20263 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20322

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20323 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20380

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20381 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20439

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20440 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20498

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20499 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20555

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20556 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20615

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20616 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20675

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20676 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20732

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 20733 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20792

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 20793 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20852

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 20853 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20908

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 20909 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20968

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 20969 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 21024

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 21025 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21079

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 21080 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21137

Query: 1616  NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
             N  G  +P   T       +PAP  DL     T TS+   WT P+      +T Y V   
Sbjct: 21138 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21197

Query: 1668  PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
              K E+T     I+    +  + VS L   +  E  V+A  +   S P   G +T  E + 
Sbjct: 21198 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 21254

Query: 1726  PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
              P          +  V       + + ++ K +    +  D +P      ++  +T    
Sbjct: 21255 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 21314

Query: 1775  VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
               S      + G  Y + L    DNA     V      +  PS     +RF     +S++
Sbjct: 21315 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 21370

Query: 1831  VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
             +SW  P       IT Y I+  +      ++V       T   +  L    EY   V A 
Sbjct: 21371 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 21429

Query: 1887  KNNQKSEPLI 1896
                  S+PL+
Sbjct: 21430 NRYGVSQPLV 21439



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1485 (20%), Positives = 517/1485 (34%), Gaps = 213/1485 (14%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
             S+ + T +S ++SW            EY +  +G   Q       + +  I ++   ++ 
Sbjct: 21165 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 21223

Query: 787   IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
              V  +++    E+ L   ++    T  +    P VD  D     + VR          Y+
Sbjct: 21224 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 21283

Query: 843   IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
                 PS+      L L E        T N +TLS      ++      + +N      V 
Sbjct: 21284 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 21343

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
             I   T G P     P    ++F E+    V + W  PE      +T Y ++    +    
Sbjct: 21344 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21399

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
                   ++R TF +V  L     Y F+V A +    S+PL      A+   ++  P    
Sbjct: 21400 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 21458

Query: 1005  FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
              + N T   + + W  P     +++TG+ +          ++ N  P S  +Y    L  
Sbjct: 21459 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 21518

Query: 1059  ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
               +Y   + A       SP     FT        P  P   +VT  TI + W P  R G 
Sbjct: 21519 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 21578

Query: 1116  K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                    +   QG E  R V  +   +      V+GL+PG  Y + I            I
Sbjct: 21579 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 21624

Query: 1167  VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
                 V  +SPP+                +E  P+   G++  S E      +   R    
Sbjct: 21625 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21684

Query: 1212  PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
              T  + G  +E+ ++    D    T   +      +  VYTV+    S        V + 
Sbjct: 21685 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
             DT    V P   +RFTNI  + M + W  P +     +T++++             ED  
Sbjct: 21745 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 21801

Query: 1313  ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
             E   + S  A+ L N   G EY   VS+V +     PL         Q T  D+P   + 
Sbjct: 21802 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21855

Query: 1367  SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
             S+IT NS T+ W  P     + I  Y +    +  +   +   + P S     +T LT G
Sbjct: 21856 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21915

Query: 1422  TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
              EY   ++A N     P      LI  +  V+    P  ++V   + T++ + W  P   
Sbjct: 21916 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21975

Query: 1475  VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
                  I Y      + + ++    +    K+  T++ L+ G +Y   V A+   G+GDS 
Sbjct: 21976 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 22035

Query: 1528  --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
                 + K +      E+D  +  + T V     S++ ++      T   V + P +    
Sbjct: 22036 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 22095

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
                       + +T+E          ++  +N SG         V   P P   + F  V
Sbjct: 22096 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 22155

Query: 1644  TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
             T  S +  W  P +   G R+     EK    +     I+         V+ L     Y 
Sbjct: 22156 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22214

Query: 1700  VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
               V A+ +     P +    +   E  +PPRR  V D ++++  ++W          ITG
Sbjct: 22215 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 22274

Query: 1754  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
             + ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S  I
Sbjct: 22275 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22333

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT---- 1866
               P         P + L         IT  +I   K GSP    VP   RP P VT    
Sbjct: 22334 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVTWKLE 22379

Query: 1867  --------EATITGLEPGTEYTI----------YVIALKNNQ-------------KSEPL 1895
                       +IT  +  T  T+          Y + L+N               +  P+
Sbjct: 22380 EMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPV 22439

Query: 1896  IGRKKTGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 1950
              G  +    +     +SW   +D      + YI+     GT    L        T   +T
Sbjct: 22440 TGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL-VNSSVKRTQIKVT 22498

Query: 1951  GLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE 2010
              LT+   Y+  V +   + R  V + + +           P+  +  + Y VS  A+   
Sbjct: 22499 HLTKYMEYSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22555

Query: 2011  WERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGV-----NYKI 2050
             WE     G     + +G+       ++  W  +N V     NYK+
Sbjct: 22556 WEEPYHDGGS---KIIGYWVEKKERNTILWVKENKVPCLECNYKV 22597



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 272/1331 (20%), Positives = 495/1331 (37%), Gaps = 207/1331 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8910  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8967

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8968  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 9014

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 9015  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9074

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 9075  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9130

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 9131  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 9191  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9247

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9248  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9307

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9308  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9363

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9364  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9423

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9424  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9479

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9480  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9539

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 9540  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9598

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 9599  CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9657

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 9658  PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9717

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 9718  ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9777

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 9778  EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9837

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 9838  VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9897

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 9898  G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9954

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T     +
Sbjct: 9955  N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010

Query: 1632  IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
             +P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N  P  +
Sbjct: 10011 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 10068

Query: 1686  -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
                  S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP     +V
Sbjct: 10069 MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 10124

Query: 1733  TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
             TD T+++  + W    +     +TG+ V+     G+   ++    +VR     +TGL+ G
Sbjct: 10125 TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 10183

Query: 1787  TDYKIYLYTLN 1797
               YK  +  +N
Sbjct: 10184 AFYKFRVRAVN 10194



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)

Query: 609  SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
            S P E+   E P+ P S P+  +        K+I + W+P  KN     +G   E    G
Sbjct: 7965 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 8022

Query: 662  -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
                  +NS  IK LK     GVV + + +    ++   G  E +       +   P   
Sbjct: 8023 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 8081

Query: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
             T+  ET     +     S+  +   +  V  VS        +    L+ + D       
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 8134

Query: 769  PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               +  + +P  +     I  +   ++ G  +  ++      P    D     +  +S  
Sbjct: 8135 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8192

Query: 829  VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
            + W  P+     PI  Y +    +   +   +   E   S T+ DL P  +Y   + AV 
Sbjct: 8193 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 8252

Query: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
            +      + ++              P D++    T   +TI W PP     S + GY ++
Sbjct: 8253 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 8312

Query: 941  VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
             I     GE   +      +PI   T     GL  G  Y F+V A +    S+P  A   
Sbjct: 8313 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 8366

Query: 995  TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
            TK    +DAP     T+L+ V   D   L           + W      I    +     
Sbjct: 8367 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 8425

Query: 1032 GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
             L RR     Q  +  V P   +  + N +                  Y + +    G  
Sbjct: 8426 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 8485

Query: 1074 ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
            ++P    V  T  PG  I     ++ +T+++  W P    G    +  +   E   +   
Sbjct: 8486 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 8541

Query: 1134 DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
            DS  IVV+            L  G EY++ ++   +      P V+K +    P  PP  
Sbjct: 8542 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 8600

Query: 1179 -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
             +  +  +  +  + V W   +     I GY +     N    + + + +  +      D
Sbjct: 8601 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 8659

Query: 1236 NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
             L  GL Y   V         +  P SD      P  PP P   R T+    T+ + W P
Sbjct: 8660 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8719

Query: 1290 PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
            P      ++  + V    V   E               +  +  G +Y + VS+V    E
Sbjct: 8720 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8779

Query: 1347 STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
              P   +  T  +   P  ++          +        + G  +R  P   +GRP   
Sbjct: 8780 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 8830

Query: 1405 RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
            +V         ++ + + N+   +E ++            I A N           +  V
Sbjct: 8831 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 8888

Query: 1448 SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
             DVP    DL+ V       L++W  P            E  G S +  F +        
Sbjct: 8889 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 8936

Query: 1500 ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
                     +S   I+GL  G +Y   V A    G  P    P+ I     +D       
Sbjct: 8937 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 8992

Query: 1545 PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            P ++  T+   ++I++ W        SP+ GY +     + P   +        T   +E
Sbjct: 8993 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 9052

Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
             L     Y   V A N  GES+P       ++P    ++  +V PT    LS +     V
Sbjct: 9053 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 9105

Query: 1658 QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
            +  G  V + P + TG PM +I  + + + +   +  +  TK EVS             V
Sbjct: 9106 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163

Query: 1703 YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
               K T T   +  + +   NV        SPPR   VTD    +  ++W    +     
Sbjct: 9164 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 9223

Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
            IT + +D   A+ +      +      + Y I  L P   Y+  +     Y ++D  +S 
Sbjct: 9224 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 9283

Query: 1804 PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
             VVI D       P   + LA T  S+LVSW PP     + ITGY ++  + GSP    V
Sbjct: 9284 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 9343

Query: 1859 PRPRPGVTEATITGLE 1874
               R  +T+  + G+E
Sbjct: 9344 --SRAPITKVGLKGVE 9357



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 171/752 (22%), Positives = 283/752 (37%), Gaps = 116/752 (15%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 9772  TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9831

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 9832  VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9885

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 9886  TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9943

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 9944  ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9996

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 9997  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 10056

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 10057 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 10113

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 10114 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10173

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
             ++ + GL+    Y   V A N +G  +P   T V       ++K   V+P   L A    
Sbjct: 10174 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 10227

Query: 1655  PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
               V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   V
Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10287

Query: 1703  YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
             Y+L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + 
Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10347

Query: 1756  VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
             ++   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+
Sbjct: 10348 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10405

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
              +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V    
Sbjct: 10406 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10465

Query: 1863  PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 + T+ GL+ G  Y   V A+    + +P
Sbjct: 10466 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10497



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 258/1144 (22%), Positives = 397/1144 (34%), Gaps = 207/1144 (18%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
             P P ++L+   VT    TI W  P     S +T +   ++    P + G  +  S  T  
Sbjct: 11697 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNF---IVEYRKPNQKGWSIVASDVTKR 11753

Query: 963   EV-TGLSPGVTYYFKVFA-----VSHGRESKP--LTAQQTTKLDAPTNLQFVNETDSTVL 1014
              +   L     YYF+V A     V    E+K   L      +   P NL   ++  + V 
Sbjct: 11754 LIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVY 11813

Query: 1015  VRWTPPRAQITGYRLTVGLTRR------------GQPRQ--YNVGPSVS------KYPLR 1054
             ++W  P        L+  + RR            G  ++  Y V   V       +   +
Sbjct: 11814 LKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTK 11873

Query: 1055  NLQPASEYT-VSLVAIKGNQESP----KATGVFTT-------LQPGSSIPPY-NTEVTET 1101
             N    S++     V +K + + P    K +GV T        L+ G    P+     T+ 
Sbjct: 11874 NEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD 11933

Query: 1102  TIVITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVY--TIQVLRD 1158
                   T +PR+  K+  R  S      +   SD G  VV+       +V   T+ VL  
Sbjct: 11934 KDATDLTRSPRV--KIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL-- 11989

Query: 1159  GQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVS---WERSTTPDI--TGYRIT--- 1209
               ++  P+ N K+V   S    +  +   D G   +     E+  T  +  + Y  T   
Sbjct: 11990 --DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLT 12047

Query: 1210  --TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
               TT T   +GN     V A+    T     P  E    +   K DK          P  
Sbjct: 12048 PGTTVTRLIEGNEYIFRVRAENKIGT----GPPTESKPVIAKTKYDK----------PGR 12093

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVV 1324
             P P ++  T +  + M V W PP      +    +   K +     + ++ S   +  + 
Sbjct: 12094 PDPPEV--TKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMK 12151

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDS------PTGIDFSDITANSFTVH 1377
             + NLLP  EY   V +  E     P L  R     D       PT     D T +S T+ 
Sbjct: 12152 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 12211

Query: 1378  WIAP----RATITGYRIRHHPEHFSGRPRED------RVPHSRNSITLTNLTPGTEYVVS 1427
             W  P     A I GY +   P+     P E            R   T+T+L    EY   
Sbjct: 12212 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 12271

Query: 1428  IVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
             + A N      + IG+ + + +  +  E++      L  S     V VR           
Sbjct: 12272 VCAQN-----QVGIGRPAELKEAIKPKEILEPPEIDLDASM-RKLVIVR----------A 12315

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTIT-------------VYAVTGRGDS------- 1527
               P++ F +   +    ++  K G+D  +              V   + R DS       
Sbjct: 12316 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 12375

Query: 1528  --PASSKPISINYRTEIDKP---SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
               PA  K + +N R  +D P   S ++V+DV   S  V W P      S VT Y V    
Sbjct: 12376 VNPAGEKAVFVNVRV-LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKRE 12434

Query: 1579  KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTT 1631
              +      T T    +T   +  L P  EY   V A N  G   P       L    ++ 
Sbjct: 12435 ADRK-TWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE 12493

Query: 1632  IPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
                P  L+ T++T  S +  W PP        +  +T YR    P ++     E ++  D
Sbjct: 12494 PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKD 12550

Query: 1684  SSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----- 1736
              S +VV+GL    KY+  V A      S P  A+GV    E + PP+       T     
Sbjct: 12551 LS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGK 12609

Query: 1737  ----------ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGL 1783
                       +   T  W+  + E +T   +    A+  +   I+   + D   Y++T  
Sbjct: 12610 KLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAE 12669

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----AR 1839
                           D  +   VV+DA      P ++  +     SL  SW  P     + 
Sbjct: 12670 NSSG---------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSN 12718

Query: 1840  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1899
             IT YI++ +   S    V        T   +  L PG EY   V A      SEPL   K
Sbjct: 12719 ITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPK 12777

Query: 1900  KTGQ 1903
                Q
Sbjct: 12778 MVAQ 12781



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 117/534 (21%), Positives = 206/534 (38%), Gaps = 63/534 (11%)

Query: 1414 TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
            T+T L  G  EY+  + A N          ++P+    +  V   P ++ +       + 
Sbjct: 6844 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 6903

Query: 1466 ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
            ++W+ P       +  Y I   +          TV     +AT++ +  G +Y+  V A 
Sbjct: 6904 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 6963

Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
               G    S+    +     I++PS    +  +D   +S+ +KW P      SP+ GY +
Sbjct: 6964 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 7023

Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
                +      +       +    + GL+   +Y+  V A+N +G S P      + I  
Sbjct: 7024 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 7077

Query: 1635 PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
            P       V PT  LSA     +   PN     V  TGY R   T        +TG   +
Sbjct: 7078 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7137

Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
            +      + +V+S    + + +  +Y LK     +   G   V  +   S P+  +  D 
Sbjct: 7138 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 7194

Query: 1736 TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
            T+ ++ ++W    +     +TG+ V+    + +T  +         +T+  L  G +Y  
Sbjct: 7195 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 7254

Query: 1792 YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
             +   N      P  +D        +T  D P N+++   T NS+ ++W PP+    +RI
Sbjct: 7255 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 7314

Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             GYI++    GS        P    T+  +TGLE G  Y   V AL     S+P
Sbjct: 7315 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7367



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)

Query: 806  SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
            S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 6881 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6940

Query: 861  TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
               S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 6941 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6995

Query: 916  VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
             + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 6996 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 7055

Query: 972  TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
             Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 7056 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7115

Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
             PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 7116 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7171

Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
            +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 7172 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7226

Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
            +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 7227 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7286

Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
             N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 7287 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7344

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
              L  G  Y   V  +     S P   T  I AV                          
Sbjct: 7345 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7403

Query: 1272 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
            +L  T  G    ++TW     I   +  +    V  +  V  +    SD          G
Sbjct: 7404 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 7454

Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
            T  + +V+          +    K G   P   D +D+T  S  + W  PR    + IT 
Sbjct: 7455 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7512

Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
            Y +         R  +  V H  +S         T L P  EY+  + A N        +
Sbjct: 7513 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 7565

Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
             SP+    Q      P  LE    T  ++ ++W  P       +  Y +   +   +  V
Sbjct: 7566 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7625

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
            +   +P   +T  + GL     Y   V A  + G G    S++PI I  +  ID P    
Sbjct: 7626 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 7683

Query: 1547 QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
            +  V DV   S+ + W        + +  Y V    K G         G   T+  + GL
Sbjct: 7684 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 7742

Query: 1603 QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
                EY   V A N +GES+P       L +  +     P  L+   +T  +   +WT P
Sbjct: 7743 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 7802

Query: 1656 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
                   +T Y V      + G  + ++     +   V+ L      E S+Y  +    +
Sbjct: 7803 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 7856

Query: 1712 RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
               Q   T +E+            PP    V D T+  + + W          I  + ++
Sbjct: 7857 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 7916

Query: 1758 AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
                 G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P        + D
Sbjct: 7917 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 7975

Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
             ++    P +L         + ++W+PP     + I GY ++    G+     V  RP  
Sbjct: 7976 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 8035

Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             +      G+ P  EY + V A+     SEP
Sbjct: 8036 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 8066



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 265/1308 (20%), Positives = 462/1308 (35%), Gaps = 209/1308 (15%)

Query: 814   PPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
             P D T D     S+ + W  P     + IT Y +    +   S +         +  ++ 
Sbjct: 14571 PTDITKD-----SVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTG 14625

Query: 870   LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWT 928
             L  G +Y   + A  E     P     ETT   ++   PSP D L  +++T   V++ W 
Sbjct: 14626 LSEGCEYFFRVMAENEYGIGEPT----ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWP 14681

Query: 929   PPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHG 983
              P+    S +TGY   VI     G +    +   +     V  L+ G  Y F+V AV+  
Sbjct: 14682 KPKHDGGSKITGY---VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSA 14738

Query: 984   -----RESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
                  RES+P+  ++ T L     L         V+ +         G  + V +   G+
Sbjct: 14739 GRSAPRESRPVIVKEQTMLP---ELDLRGIYQKLVIAK--------AGDNIKVEIPVLGR 14787

Query: 1039  PRQ---YNVGPSVSKYPLR-NLQPASEYTVSLV--AIKGNQESPKAT--------GVFTT 1084
             P+    +  G  + K   R N +  +  T+  +   ++ +      T        G   T
Sbjct: 14788 PKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVIT 14847

Query: 1085  LQ----PGSSIPPYN-TEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSG--- 1136
             +Q    PG    P    EV+   +  +W P    G   GV  S      R+  S +    
Sbjct: 14848 IQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDG---GVPISNYVVEMRQTDSTTWVEL 14904

Query: 1137  -------SIVVSGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEA 1184
                    +   + LT G+EY + ++      +  G      + N       PP    + A
Sbjct: 14905 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14964

Query: 1185  NPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGL 1241
                   +T+SW    +     I GY +     NG    ++ + +    +      L+ G+
Sbjct: 14965 VTKDS-MTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKAL-VPGNIFKSSGLTDGI 15022

Query: 1242  EYNVSVYTV------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---S 1292
              Y   V         K  K S P+    +  + PP      NI   T+ + WA P     
Sbjct: 15023 AYEFRVIAENMAGKSKPSKPSEPM--LALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGG 15080

Query: 1293  IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
               +T+++V    + N   +     +  +N   ++ L     Y   V +       +P   
Sbjct: 15081 FKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSE 15140

Query: 1353  RQ-----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY 1388
                    +  +++P     + F D        +F            T+ W      + G 
Sbjct: 15141 PSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGT 15200

Query: 1389  -RIRHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIG 1442
              ++      FS     +D       + TLT   PG   +++ ++  L+  G  E PL + 
Sbjct: 15201 AKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVT 15260

Query: 1443  QQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPG 1498
             +                T    ++SW  P       + +Y +   ET   +    +T   
Sbjct: 15261 E---------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVA 15301

Query: 1499  SKSTAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDV 1553
             S+   T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +
Sbjct: 15302 SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTI 15361

Query: 1554  QDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
               +S+ V W        S +  Y V    K G    K            + GL    EY 
Sbjct: 15362 TKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYE 15421

Query: 1610  VSVYAQNPSGESQPLVQT----AVTTI---PAPTDLKFTQVTPTSLSAQWTPP----NVQ 1658
               + A+N +G S P   +    A  T+     P + +    + +S+S  W  P      +
Sbjct: 15422 FRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSE 15481

Query: 1659  LTGYRVRVT-PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--Q 1715
             +TGY V +  P+E    +        ++S  ++GL    +Y++ +YA+       PA   
Sbjct: 15482 ITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVP 15541

Query: 1716  GVVTTLENVSPPR-------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
             G     + + PP        R  VT     T+ +    K       +V     +G++  +
Sbjct: 15542 GTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAP--EVKWARDHGESLDK 15599

Query: 1769  RTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLA 1823
              +I+    SYT  I G     D   Y+ T+ +++ S    ++    +D P    +L+   
Sbjct: 15600 ASIE-STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV-LDTPGPPQDLKVKE 15657

Query: 1824  TTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1879
              T  S+ ++W PP     ++I  YI++  +        V       T   +  L+ G  Y
Sbjct: 15658 VTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVAT-NCHKTSWKVDQLQEGCSY 15716

Query: 1880  TIYVIALKN-------------NQKSEPLIGRKKTGQEAL-SQTTISWA-PFQDTSE--- 1921
                V+A                     PL   K T  +   +  ++SW  P  D      
Sbjct: 15717 YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRIL 15776

Query: 1922  -YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 1968
              YI+     G+D+      V    T AT+TGL +G  Y+  V A  ++
Sbjct: 15777 GYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEK 15822



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 16045 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16104

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 16105 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16149

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 16150 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16209

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 16210 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16267

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 16268 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16321

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 16322 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16378

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 16379 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16438

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 16439 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16497

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 16498 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16557

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 16558 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16617

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 16618 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16674

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 16675 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16729

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 16730 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16788

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 16789 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16848

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 16849 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16906

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 16907 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16964

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 16965 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 17016

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 17017 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17076

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
                   + +  L+   EY   ++A+N  G     ES P+V       P P    F T ++
Sbjct: 17077 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17130

Query: 1645  PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
               S+  QW  P       + GY +    +      K        +      L    +YE 
Sbjct: 17131 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17190

Query: 1701  SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
              VYA       + ++        +   PP            IT+ W          ITG+
Sbjct: 17191 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17250

Query: 1755  QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
              V+        P  R +K    +     +T++GL     Y+  +   N
Sbjct: 17251 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17294



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 21470 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21529

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 21530 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21574

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 21575 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21634

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 21635 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21689

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 21690 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21748

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 21749 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21804

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 21805 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21863

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 21864 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21922

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 21923 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21981

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 21982 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 22040

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 22041 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22100

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 22101 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22159

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 22160 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22218

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 22219 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22278

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 22279 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22335

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 22336 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22391

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 22392 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22443

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 22444 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
              +EY   V ++N  G S+PL    +      +P  APT  +   V+  ++S +W  P   
Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22562

Query: 1656  -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
                ++ GY V    +     +KE  +     +  V+GL+   +Y+   YAL     S+ +
Sbjct: 22563 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22622

Query: 1715  QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
             +    +     V  P R  VTD T +T+++ W          + G+ ++  P +      
Sbjct: 22623 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 22682

Query: 1764  QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
                   TI  D   +T+T L  G  Y+  +   N
Sbjct: 22683 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 22715



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)

Query: 1412  SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
             S  +T L  G EY   I+A+N        E  P++      V D P+  EV   T  S++
Sbjct: 16390 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 16449

Query: 1466  ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             + W+ PA      +  Y +   +  G    +       +    ++GL    DY   V A 
Sbjct: 16450 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 16509

Query: 1522  TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
                G    SP S+   + +   +   P+  +V D+  +S+ + W          + GY V
Sbjct: 16510 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 16569

Query: 1575  TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
                  + G     T   G ++T + +E L    EY   + A N +G  +        +V+
Sbjct: 16570 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 16629

Query: 1627  TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
               +       DL+  ++                   + R TP+ K     G +++  +  
Sbjct: 16630 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 16685

Query: 1683  DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
              +SS     L    +Y+   Y L  +++  ++ A   V  L+  SPP   +VT+ T+ ++
Sbjct: 16686 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16745

Query: 1741  TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
             +I+W          I  + V+   A  ++           S+ I  LQ G  Y   +   
Sbjct: 16746 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16805

Query: 1797  NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
             N+     P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +
Sbjct: 16806 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16865

Query: 1849  KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                S       R +    +A IT L  G EY   V+A+    +S+P
Sbjct: 16866 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 16909



 Score = 78.6 bits (192), Expect = 6e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19763 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19822

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19823 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19874

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19875 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19926

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19927 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19984

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19985 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 20044

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 20045 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20101

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 20102 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20155

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 20156 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20206

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20207 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20266

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20326

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20327 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20385

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20441

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 20442 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20486



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 278/1381 (20%), Positives = 487/1381 (35%), Gaps = 191/1381 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 10966 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 11022

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 11023 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11081

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 11082 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11141

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 11142 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11199

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 11200 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11254

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 11255 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11312

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 11313 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11372

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 11373 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11432

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 11433 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11492

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 11493 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11551

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 11552 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11611

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 11612 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11669

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 11670 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11720

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 11721 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11778

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 11779 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11838

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 11839 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11896

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 11897 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11946

Query: 1599  IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
             I+    + ++ ++           V A N +G         V   P P  +LK   V+  
Sbjct: 11947 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 12006

Query: 1647  SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
               +  W PP     G  ++    EK    K +  +  S++V+  G  V    E + Y  +
Sbjct: 12007 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 12064

Query: 1707  DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
                 ++   G  T  + V           P    VT  ++  +T+ W        ++ITG
Sbjct: 12065 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 12124

Query: 1754  FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
             + ++    +     P+ ++  P+ R   +  L P  +Y+  +   N+      +  S PV
Sbjct: 12125 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 12183

Query: 1806  VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
             V  D       P+N R + TT +S+ + W  P     A I GY+++       + P E  
Sbjct: 12184 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12243

Query: 1859  PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWA 1914
              R          E T+T L+   EY   V A     +++  IGR    +EA+    I   
Sbjct: 12244 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA-----QNQVGIGRPAELKEAIKPKEILEP 12298

Query: 1915  P 1915
             P
Sbjct: 12299 P 12299



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 210/1000 (21%), Positives = 366/1000 (36%), Gaps = 157/1000 (15%)

Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
            P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 6787 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6846

Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
            GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 6847 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6904

Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
            +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 6905 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6963

Query: 1251 KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
                   P + T    V        PP +L  ++    ++++ W PP     S  L   +
Sbjct: 6964 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 7023

Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
             R    K+      + + P +    +T L  G +Y+  VS+  +   S P         D
Sbjct: 7024 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7082

Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
                    D++A    +  I P           +P   +     D+V  + + + +  L+
Sbjct: 7083 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 7142

Query: 1420 PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
               E V+S    + +    L L  +  T+S             P++L+    T  S+ ++
Sbjct: 7143 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 7202

Query: 1468 WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
            W+ P            +  G SP+  + V   + +                T+  L  G 
Sbjct: 7203 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 7250

Query: 1513 DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
            +Y   V A    G G+     +P++++    + D P  ++  D   NSI + W P     
Sbjct: 7251 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 7310

Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
             S + GY V   P+   G  K    G    +T+M + GL+    Y   V A N  G S+P
Sbjct: 7311 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7367

Query: 1624 LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
               T    AV T  AP           L     T   L A  T  P  ++T  +  +  K
Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7427

Query: 1670 EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
            +     K I +   P  S+V +   + + + +   Y ++       A  VV    L+   
Sbjct: 7428 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 7480

Query: 1726 PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
            PP    +TD T  +  ++W    +     IT + V+    + +    +  T+K    ++ 
Sbjct: 7481 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 7538

Query: 1780 ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
             T L P  +Y        +Y + +  ++SP  I A    D    P+ L     T +++ +
Sbjct: 7539 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 7596

Query: 1832 SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
            +W  P     + ITGY ++   P +       +     T   + GL    +Y   V+A  
Sbjct: 7597 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 7656

Query: 1887 -----KNNQKSEPLI-----------GRKKTGQEALSQTTISWA-PFQD----TSEYIIS 1925
                 K ++ +EP++           G+        +   ++W  P  D       Y+I 
Sbjct: 7657 LAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIE 7716

Query: 1926 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                GTDE  ++      +T   L GL  G  Y+  V A+
Sbjct: 7717 MLKTGTDEW-VRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7755



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 316/1566 (20%), Positives = 536/1566 (34%), Gaps = 237/1566 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
             P  V +T+T     S  ++W+ P       I  YI+    K  +G W +      + + Y
Sbjct: 21952 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 22008

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
             T+  L+ G  Y+ ++ +I   G  +         S     T   V   T P   + A  +
Sbjct: 22009 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 22059

Query: 727   SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
                 + A + +  +++     + T    + +  LS   D     D  ST T  N      
Sbjct: 22060 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 22118

Query: 783   GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
             G KY + V   S  G +S+  +      P  P   T   V   S  + W  P     A I
Sbjct: 22119 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 22175

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
               Y +    +   S   ++   T     ++DL  GV Y   + AV E     P  + +  
Sbjct: 22176 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22235

Query: 899   TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
               T +      PR L  V+ +     + W  P+    S +TGY +++        +   H
Sbjct: 22236 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 22292

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
              ++L  +     E T       Y F+V A +    S+P  A  +  +  P          
Sbjct: 22293 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 22337

Query: 1011  STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
                      P A +TG    +   + G P   +V       P V+ + L  ++      V
Sbjct: 22338 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 22389

Query: 1065  SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
             S+   K       ++S +      F TL+  + +  ++      T+V+   P P  G   
Sbjct: 22390 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 22444

Query: 1115  ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
                          G  P  GG    E+T+      +SG+              I V+ LT
Sbjct: 22445 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22501

Query: 1145  PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
               +EY + +    R G  +    API+  +  V P +P  P   H+ AN     +++ WE
Sbjct: 22502 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 22557

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
                     G +I       ++ N++    E  V   + +     L  GLEY    Y +  
Sbjct: 22558 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22615

Query: 1251  ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
                 K  + S PI       V  P     T++   T+ + W+ P       +  +++   
Sbjct: 22616 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 22673

Query: 1304  PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
             PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+  R
Sbjct: 22674 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 22733

Query: 1354  Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
                   K  LD+    D   I A S  V   A    P   I   +     +       + 
Sbjct: 22734 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 22793

Query: 1405  RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
                 +   I   + +   +Y +++   +G +   +++     V D P     L V   T 
Sbjct: 22794 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 22849

Query: 1462  TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
                 ++W  P       + +Y +   ET   S +    V G   T +  ++ L    +Y 
Sbjct: 22850 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 22906

Query: 1516  ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
               V AV   G   P  S+PI       I  P  + +        I ++W    S     +
Sbjct: 22907 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 22966

Query: 1570  TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             + Y V    K     T+  K      T + +  L    +Y   V A N +G S+P   + 
Sbjct: 22967 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 23026

Query: 1629  VT-------TIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK- 1676
                      T   P+  +    T  S+S  WT P       + GY + +  K+     + 
Sbjct: 23027 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 23086

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTD 1734
               N    ++   V  L +  KY   V A+     S  ++ +  +  +E +  P    + D
Sbjct: 23087 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD-LELAD 23145

Query: 1735  ATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
               + T+TI        +        P       G     R I     SY++  +     Y
Sbjct: 23146 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 23205

Query: 1790  KIYLYTL---NDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPR----ARIT 1841
                 YT+   N + + S  V+        P  +++    + +S+ ++W+ P     A + 
Sbjct: 23206 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVN 23265

Query: 1842  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP------- 1894
              YI++  +      + V   +   T   I+GL  GT Y   V+        EP       
Sbjct: 23266 NYIVEKREAAMRAFKTVTT-KCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAV 23324

Query: 1895  ------LIGRKKTGQEALSQT-TISWA-PFQDTSE----YIISCHPVGTDEEPLQFRVPG 1942
                   L+  K    +    T T++W  P  D       Y++     GT+       +  
Sbjct: 23325 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23384

Query: 1943  TSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTV 2002
             T    T+T L  G  Y   + A  ++   + RE V  V  +V +    PT D    P   
Sbjct: 23385 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAV--TVQDLRVLPTIDLSTMPQKT 23442

Query: 2003  SHYAVG 2008
              H   G
Sbjct: 23443 IHVPAG 23448



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 20222 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20276

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 20277 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20336

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 20337 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20394

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 20395 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20451

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 20452 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20509

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 20510 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20569

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 20570 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20625

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 20626 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20685

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 20686 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20745

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 20746 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20801

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 20802 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20859

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 20860 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20918

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 20919 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20977

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 20978 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 21037

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 21038 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21154

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 21155 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21211

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
             T E+ +  L+        V+A+N  G S P+      TI  P  +K   +TP   LS   
Sbjct: 21212 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 21261

Query: 1653  TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
               P  Q+T   G+ V +    K  P   I+   D   +  S  +  +K E  +  ++K+ 
Sbjct: 21262 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21321

Query: 1709  LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
                   +             V  T+  + PP +     R  +    ++ +SW    +   
Sbjct: 21322 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21381

Query: 1751  --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
               IT + ++      QT  +       R ++ +  L    +Y+  +   N    S P+V 
Sbjct: 21382 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21440

Query: 1808  DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
                 A         P        T + + ++W  P     + +TG+ ++ ++  S   + 
Sbjct: 21441 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 21500

Query: 1858  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             V        E   TGL  G +Y   V A  +   S P
Sbjct: 21501 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21537



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 9187 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9244

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9245 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9297

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9298 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9351

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9352 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9411

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9412 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9471

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9472 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9503



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24421 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24475

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24476 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24535

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24536 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24595

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24596 CENLGGESEWSEISEPI--TPKSD 24617



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24804 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24861

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24862 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24921

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24922 EVDETREVSMT 24932



 Score = 35.8 bits (81), Expect = 0.47
 Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)

Query: 1534  ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
             + +  + + DKP+   V + +  NS  + W P +    S +T Y V           +  
Sbjct: 24410 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24469

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
             ++    T   I  L     Y   V AQN  G S PL  ++V  I +P +          T
Sbjct: 24470 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24529

Query: 1642  QVTPTSLSAQWTPP 1655
              VT  S    W PP
Sbjct: 24530 AVTKDSCVVAWKPP 24543


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score =  149 bits (376), Expect = 3e-35
 Identities = 294/1431 (20%), Positives = 527/1431 (36%), Gaps = 186/1431 (12%)

Query: 607   SSSGPVEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGR 653
             S S  +++ + + P  P S  I           W  P     S I+ YI+  R + S   
Sbjct: 13004 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKR-ETSRPN 13062

Query: 654   WKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
             W + +    + S +++ L  G  Y+ ++ +  +YG                PV +     
Sbjct: 13063 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYG-------------VGDPVFTEPAIA 13109

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLP 769
             +     P       ++ IT     VSW   +D     ++G+ +E   ++  +  +    P
Sbjct: 13110 KNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKP 13169

Query: 770   STATSVNIPDLLPGRKYIVNVYQISE--DGEQSLILSTSQTTAPDAPPDPTV-DQVDDT- 825
                 ++    L  G +Y   V  I++   G+ S     +    P  PP P    +V DT 
Sbjct: 13170 IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTT 13229

Query: 826   --SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT--LSDLQPGVQYN 877
               S+ + W +P     +PI GY +    +   +    NLP+        ++ L    QY 
Sbjct: 13230 RSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQ 13289

Query: 878   ITIYAVEENQESTPVVIQQETTGTPRSDTVPSP----RDLQFVEVTDVKVTI-MWTP--- 929
               +YAV +   S P  +  +    P+   +P       DL+   +    VT+ ++ P   
Sbjct: 13290 FRVYAVNKIGYSDPSDVPDKHY--PKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKG 13347

Query: 930   -PESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSP-GVTYYFKVFAVSHGRES 986
              P   +T  + +V   NL    G  +  +  +TF     ++      Y      S G++ 
Sbjct: 13348 RPPPKITWSKPNV---NLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 13404

Query: 987   KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY 1042
               +  +       P N+     +  +  V W PP     + I  Y +      R      
Sbjct: 13405 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13464

Query: 1043  NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
                 S + + + NL+    Y   + A               V  +  PG  +      V+
Sbjct: 13465 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 13524

Query: 1100  ETTIVITWTPAPR------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
             +++  I W           IG+ +     +  +  R + S S       LT G EY + +
Sbjct: 13525 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSAKDLTEGKEYTFRV 13583

Query: 1154  QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL-------------------TVS 1194
                 +  E     +  V        +L L+  PD   L                   +VS
Sbjct: 13584 SAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13643

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD-NLSPGLEYNVSVYTVKDD 1253
             W++   P  T  R++             E    + +   +D   S   +Y +++  V   
Sbjct: 13644 WKKGEDPLATDTRVSV------------ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 13691

Query: 1254  KESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             KE   IS  ++     PT  ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 13692 KEGT-ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13750

Query: 1310  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1363
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 13751 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13809

Query: 1364  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 13810 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13869

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS----DVPRDLEVVAATPTSLLISWDAPAVTV 1475
              G EY   ++A+N        +  +  V+    D P   EV+  T  S+ + W  P    
Sbjct: 13870 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13929

Query: 1476  RY----YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
              +    Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 13930 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 13989

Query: 1532  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1575
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 13990 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 14049

Query: 1576  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAP 1635
                   P      T+ P  + +TI+          ++ A NP G     V+  V  +P P
Sbjct: 14050 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 14103

Query: 1636  TD-LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVS 1690
                ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V +
Sbjct: 14104 PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14162

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRT 1746
              L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+ 
Sbjct: 14163 KLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKR 14222

Query: 1747  KTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLN--- 1797
               +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N   
Sbjct: 14223 PVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAG 14281

Query: 1798  ----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1849
                   A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K
Sbjct: 14282 IGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 14341

Query: 1850  PGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
              G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14342 VGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14389



 Score =  148 bits (373), Expect = 7e-35
 Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 22848 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22906

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 22907 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22956

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 22957 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23013

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 23014 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23073

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 23074 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23133

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 23134 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23185

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 23186 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23244

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 23245 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23302

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 23303 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23361

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 23362 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23421

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 23422 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23481

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 23482 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23539

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 23540 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23599

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 23600 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23659

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 23660 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23719

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 23720 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23771

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 23772 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23830

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 23831 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23889

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 23890 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23946

Query: 1629  VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
               T   P +         +   VT +S+S  W+ P      ++TGY +          ++
Sbjct: 23947 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24006

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
                    ++   V+GL+   +Y+  + A  D   + TS  ++ VV     +  S P    
Sbjct: 24007 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24066

Query: 1732  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
             +   ++ ++T+ W        + I G+ V+    +G +  +++ K  +  + +TI GL  
Sbjct: 24067 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 24125

Query: 1786  GTDYKIYLYTLNDNARSSP 1804
              T+Y+  ++  N+   S P
Sbjct: 24126 ATEYEFRVFAENETGLSRP 24144



 Score =  138 bits (347), Expect = 7e-32
 Identities = 290/1321 (21%), Positives = 498/1321 (37%), Gaps = 189/1321 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13418 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13474

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13475 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13519

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13520 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13576

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13577 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13636

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13637 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13694 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13746

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13747 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13805

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13921

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 13922 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13981

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 13982 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14040

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 14041 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14093

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 14094 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14143

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 14144 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14203

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 14204 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14263

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 14264 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14323

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 14324 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14383

Query: 1526  -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 14384 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14443

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V   P P  +
Sbjct: 14444 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14501

Query: 1638  LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
             L+ T +T  S++  W  P +    ++T Y V    +++    K  + A       +  V+
Sbjct: 14502 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 14557

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
             GL    +Y   V A  +     P +    V   E  SPP    + D T++T++++W    
Sbjct: 14558 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 14617

Query: 1745  RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
                   ITG+ ++A    + Q     T+K       +  L  G +Y   +  +N   RS+
Sbjct: 14618 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 14675

Query: 1804  P 1804
             P
Sbjct: 14676 P 14676



 Score =  129 bits (323), Expect = 4e-29
 Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7404 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7462

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7509

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7510 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7569

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7570 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7629

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7687

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7688 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7747

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7748 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7806

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7807 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7866

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7867 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7926

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7927 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7985

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 7986 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8039

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 8040 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8098

Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
             I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 8099 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8158

Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
              +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8218

Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
             TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 8219 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8276

Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
            EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 8277 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8336

Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
              IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 8337 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8396

Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
            +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 8397 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8456

Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 8457 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8516

Query: 1624 LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
             V   +          AP       VT  S+  +W  P      + GY +       T  
Sbjct: 8517 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8576

Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
             +      ++    V GL+    Y   V A       +  P     T  + +SPP     
Sbjct: 8577 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 8636

Query: 1731 RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
            RVTD + TTI + W          I G+ VD          + T K   VR YT+  ++ 
Sbjct: 8637 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 8696

Query: 1786 GTDYKIYLYTLNDNARSSP 1804
            G DYK+ +  +N      P
Sbjct: 8697 GADYKLRVSAVNAAGEGPP 8715



 Score =  129 bits (323), Expect = 4e-29
 Identities = 261/1302 (20%), Positives = 465/1302 (35%), Gaps = 162/1302 (12%)

Query: 716   TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--- 772
             TP  P+  T   V EI+  S  V+W           + Y + +   E +     +T    
Sbjct: 13414 TPGPPVNVT---VKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSK 13470

Query: 773   TSVNIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  + +L  G+ Y   V     Y I + GE    +  SQT  P    D  V  V  +S 
Sbjct: 13471 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV--DLKVRSVSKSSC 13528

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
              + W +P +     I GY + +    E +  +  +   +   +  DL  G +Y   + A 
Sbjct: 13529 SIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAE 13586

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              EN E TP     E T   R D V    DL+ +        + +   E++    ++ +  
Sbjct: 13587 NENGEGTP----SEITVVARDDVVAPDLDLKGLP------DLCYLAKENSNFRLKIPIKG 13636

Query: 944   VNLPGEHGQRL--PISRNTFAEVTGLSPGVTY------------YFKVFAVSHGRESKPL 989
                P    ++   P++ +T   V   +   T             Y        G +   +
Sbjct: 13637 KPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 13696

Query: 990   TAQQTTKLDAPTN-LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNV 1044
             + +   K   PT  ++F   T   + ++W PP+    ++IT Y L    +   +      
Sbjct: 13697 SIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCAS 13756

Query: 1045  GPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKATGVFTTLQ---PGSSIPPYNTEVT 1099
                 + + +  L    EYT  + A    G  E  K+  +        P +  PP   +V 
Sbjct: 13757 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVR 13816

Query: 1100  ETTIVITWTPAPRIG--------FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
               ++ +TWT   + G         +   R S   +   +         V+GLT G+EY +
Sbjct: 13817 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13876

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTTPD---ITGY 1206
              +  +         + ++ V  L P  P       N     +T+ W          +TGY
Sbjct: 13877 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 13936

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEYNV---------SVYTVKDDKE 1255
              +       +   S  +  H +   C F   +L  G +Y           ++    +  E
Sbjct: 13937 IVEKRDLPSK---SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTE 13993

Query: 1256  SVPISD-----TII--PAVPPPTDLRFTN-IGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
             ++   D     TI+  P +     ++  + I  + + +   P P    +       P   
Sbjct: 13994 TIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP--- 14050

Query: 1308  EEDVAELSISPSDNAVVL--TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD---SPT 1362
               D+ +++ +P+ + + +         EY ++ ++ +     T +   + T LD    P 
Sbjct: 14051 -SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF----GTKVEHVKVTVLDVPGPPG 14105

Query: 1363  GIDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTN 1417
              ++ S+++A   T+ W  P     + I  Y + +            + +   R+    T 
Sbjct: 14106 PVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH--VATK 14163

Query: 1418  LTPGTEYVVSIVALN--GREE----SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L  G EY+  + A+N  G+ E     P+ +  +      P   EV   T  +  +SW  P
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14223

Query: 1472  A----VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    +  Y +   E      V+    P S     ++GL+ G  Y   V A    G  
Sbjct: 14224 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283

Query: 1528  PASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1580
             P S    S+  +        PS   VTD    S S+ W          +TGY V    K 
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY-VVEHQKV 14342

Query: 1581  GPGPTKTKTAGPDQ--TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL 1638
             G       T G     T+  +  LQ   +Y   + A N +G  +P V      IP    +
Sbjct: 14343 GDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV------IPDVEIV 14396

Query: 1639  KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS------------SS 1686
             +        L A+     V   G  +R+    K  P  E+    D+             S
Sbjct: 14397 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTES 14456

Query: 1687  VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDATETTITISW 1744
               +  +    +Y+   + +     +    G V    L+   P    R TD T+ ++T+ W
Sbjct: 14457 FTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHW 14516

Query: 1745  RTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
                       IT + V+   A  ++    T K    +Y +TGL  G +Y   +   N+  
Sbjct: 14517 DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYG 14576

Query: 1801  RSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1852
                P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY+I+ ++ GS
Sbjct: 14577 IGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS 14636

Query: 1853  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                  +   +    E  +  L  G EYT  V+A+ +  +S P
Sbjct: 14637 DQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAP 14676



 Score =  128 bits (321), Expect = 7e-29
 Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)

Query: 758  EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
            E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 7064 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7119

Query: 815  PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
             +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 7120 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7179

Query: 871  QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
              G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 7180 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7239

Query: 931  E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 7240 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7298

Query: 987  KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
            KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7353

Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 7354 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7406

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
             V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 7407 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7463

Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
             V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 7464 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7522

Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 7523 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7581

Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
               V         K  K + P  I D I P  PP  PT     ++G  ++R+ W  P   
Sbjct: 7582 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 7638

Query: 1292 -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
                + ++++       +E V      P+    +L  L+ G EY   V +V +  E    
Sbjct: 7639 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 7697

Query: 1347 --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
              S P+  R+K    S P  ++  +IT N+  + W  P     + IT Y +        G
Sbjct: 7698 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7757

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
                D         T+T LT G+ YV  + A N          E  +L     T    P 
Sbjct: 7758 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7816

Query: 1453 DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
             L VV  T   + + W+ P       ++ Y I   E  G   V+     G      ++ +
Sbjct: 7817 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7876

Query: 1509 KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
              G +    V A    G G     ++ +SI   T    P   + VTD     I++ W P 
Sbjct: 7877 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 7936

Query: 1565 ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
                 SP+ GY V   P       +  +      +  + EG+ P  EYV+ V A N  G 
Sbjct: 7937 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 7996

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
            S+P  + +   +    D K T    T          + + G ++ +    +  P+  ++ 
Sbjct: 7997 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 8048

Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
              D   V  S  +      +S + L+   + R   G+ T TLEN                
Sbjct: 8049 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8107

Query: 1724 VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
              P +  + +D T+++  ++W          I  + ++   A  +T I      +  S+T
Sbjct: 8108 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8167

Query: 1780 ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
            +  L P  +Y   +  +N          ++  +  D     D P ++     T  ++ ++
Sbjct: 8168 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8227

Query: 1833 WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
            W+PP     ++I GYII+    G    +        +   T  GLE G EY   V A   
Sbjct: 8228 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8287

Query: 1889 NQKSEP 1894
               SEP
Sbjct: 8288 AGISEP 8293



 Score =  128 bits (321), Expect = 7e-29
 Identities = 299/1394 (21%), Positives = 524/1394 (37%), Gaps = 194/1394 (13%)

Query: 604   TYPSSSGPVEVFIT----ETPSQP----------NSHPIQWNAPQ---PSHISKYILRWR 646
             T  +SSG    F+T    +TPS P          +S  I W  P     S I  YI+  R
Sbjct: 16642 TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKR 16701

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
                    +       H NS+ I  L+ G  Y  ++ +  +YG             T+ P+
Sbjct: 16702 EATRKS-YAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-------LPAQTADPI 16753

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
                 V        P      +V ++T +S  +SW           ++Y +  +    +  
Sbjct: 16754 KVAEV--------PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW 16805

Query: 767   DLPSTATSVN--IPDLLPGRKYIVNVYQISEDGE---QSL---ILSTSQTTAPDAPP--- 815
                +   S+   I +L  G +Y+  V  ++E G    +SL   I++      PD  P   
Sbjct: 16806 SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFS 16865

Query: 816   DPTVDQVDDTSIVVRWS-RPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP-- 872
               +V    D  I V  S RP+  IT  +          +T +N+ ++ +  TLS  +   
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVTDSLDLTTLSIKETHK 16922

Query: 873   --GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
               G QY IT+  V   + ++  ++  +    P+         ++F +V+   +T+ W PP
Sbjct: 16923 DDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGP-------VKFDDVSAESITLSWNPP 16975

Query: 931   ----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAV-----S 981
                    +T Y V                ++R T  +VT L  G  Y F++FA      S
Sbjct: 16976 LYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTL-KVTKLKTGTEYQFRIFAENRYGQS 17034

Query: 982   HGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTRR 1036
                ES P+ AQ   K   P    F    +  +++++W  P     + + GY L      R
Sbjct: 17035 FALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE--RKER 17092

Query: 1037  GQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI 1091
                    V  ++   +++  +NL+   EY   + A  I G  ++ K +  +    P    
Sbjct: 17093 NSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD-- 17150

Query: 1092  PPYNTE---VTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             PP   E   V    I + WT     G  +       G    +     G  + +  T  +E
Sbjct: 17151 PPGTPEPIMVKRNEITLQWTKPVYDGGSMIT-----GYIVEKRDLPDGRWMKASFTNVIE 17205

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPTNL-------------HLEANP---DTGVL 1191
               +T+  L + Q  +  ++ K     +S P++               +  +P   DT V+
Sbjct: 17206 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVV 17265

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS--------PGLEY 1243
                       D+ G  + T     +    +EE    +  +  F  L          G +Y
Sbjct: 17266 NAGETFRLEADVHGKPLPTIEWL-RGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17324

Query: 1244  NVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPP---PSIDLTNFL 1299
              +    V   K S P++  ++    PP   ++ T +  +   +TW+PP      D+++++
Sbjct: 17325 ILRASNVAGSK-SFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYV 17383

Query: 1300  VRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVY-----EQHESTPLR 1351
             V     K E      ++  S+   N++ +T LL G EYV  + +V      E  ES P+ 
Sbjct: 17384 VE----KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17439

Query: 1352  GRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSG----RPR 1402
              +    L   P  ++ ++I  +S TV W  P     + I GY +       SG    +  
Sbjct: 17440 MKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDR--SGIRWIKCN 17497

Query: 1403  EDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---EESPLLIGQQST----VSDVPRDLE 1455
             + R+   R  + +T LT   EY   + A N     E SP  +  ++         P +  
Sbjct: 17498 KRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAH 17555

Query: 1456  VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV----PGSKSTA-TISGLKP 1510
             +V  T  S+ ++W  P        + Y      +  +E+ +     G + T   IS L  
Sbjct: 17556 IVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTE 17615

Query: 1511  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1567
               +Y I V A+   G   A+S P ++    +++ P ++ +       I V+   S+    
Sbjct: 17616 HQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVRAGGSARIHI 17674

Query: 1568  PVTGY---RVTTTPKNGPGPTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
             P  G     +T + + G    K +   G + T+++I+           +  +N SG    
Sbjct: 17675 PFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 17734

Query: 1624  LVQTAVTTIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINL 1680
              V   V   P  P +L   +V   S    W PP +   G +V+  V  K ++      N+
Sbjct: 17735 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID-GGAKVKNYVIDKRESTRKAYANV 17793

Query: 1681  APDSS--SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDAT 1736
             +   S  S  V  L     Y   V A  +     P + V  V   E  SPP +  +TD +
Sbjct: 17794 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17853

Query: 1737  ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1792
             +T+ ++ W          + G+ V+  P  G        +  V +  +TGL  G +Y+  
Sbjct: 17854 QTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEKWSIVAESKVCNAVVTGLSSGQEYQFR 17912

Query: 1793  LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1852
             +   N+  +S P V      +  P   + L   P SL + +     +  G  +K E P  
Sbjct: 17913 VKAYNEKGKSDPRV------LGVPVIAKDLTIQP-SLKLPFNTYSIQ-AGEDLKIEIP-- 17962

Query: 1853  PPREVVPRPRPGVT 1866
                 V+ RPRP ++
Sbjct: 17963 ----VIGRPRPNIS 17972



 Score =  128 bits (321), Expect = 7e-29
 Identities = 307/1365 (22%), Positives = 489/1365 (35%), Gaps = 211/1365 (15%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 17706 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17763

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 17764 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17823

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 17824 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17879

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 17880 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 17937

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 17989

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 17990 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 18047

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 18048 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 18104

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 18105 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18163

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 18164 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18222

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 18223 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18279

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 18280 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18328

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 18329 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18387

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 18388 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18447

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 18448 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18506

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 18507 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18566

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 18567 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18626

Query: 1628  AVTTIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP- 1682
             A+     P++ K T  + +S+S  W+ P       + GY V V  KE           P 
Sbjct: 18627 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--KEAAADEWTTCTPPT 18684

Query: 1683  --DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP--------RRA 1730
                     V+ L   T+Y   + A+       PA   G V   E + PP        R+ 
Sbjct: 18685 GLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKV 18744

Query: 1731  RVTDATETT---ITISWR----TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1783
              V  A+ T    +TI  R     K E   G   D       +     +  +V  +     
Sbjct: 18745 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRF----- 18799

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR--- 1837
                 D   Y  TL +N+ S    ++    +D+PS   NL       +S+ +SW+PP    
Sbjct: 18800 ----DSGRYNLTLENNSGSKTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDG 18854

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT--ITGLEPGTEYTIYVIALKNN----- 1889
              A+IT YI++  +     R+         T+ T  I  L+ G  Y   V+A         
Sbjct: 18855 GAKITNYIVEKRET---TRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLP 18911

Query: 1890  -------QKSEPLI--GRKKTGQEALSQTTISWA-PFQDTSE----YIISCHPVGTDEEP 1935
                    + SEP +  GR        +  TI W  P  D       Y++     G+++  
Sbjct: 18912 AETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS 18971

Query: 1936  LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 1980
                +V   +  AT++GLT G  Y   V A+ ++ R   R+  V V
Sbjct: 18972 TCTQVK--TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 19014



 Score =  127 bits (318), Expect = 2e-28
 Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 11933 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11991

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 11992 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12051

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 12052 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12109

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 12110 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12169

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 12170 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12228

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 12229 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12287

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 12288 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12345

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 12346 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12402

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 12403 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12461

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 12462 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12520

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 12521 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12574

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 12575 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12634

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 12635 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12693

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 12694 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12743

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 12744 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12801

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 12802 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12861

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
                 +  TA     Q E T  GL+   +Y           + + + +TAV   P   P+D
Sbjct: 12862 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 12910

Query: 1638  LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
                    P ++ A+  PP + L+   +  +T K  T           PM  ++   D + 
Sbjct: 12911 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 12963

Query: 1687  V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
             +    G+ +A +  +    L     KD    T+T+  + G       +  L+   PP   
Sbjct: 12964 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13023

Query: 1731  RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
             ++         +SW    E     IT + VD    +     Q +    + S ++  L  G
Sbjct: 13024 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 13083

Query: 1787  TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
              +Y+  +   N      PV  +   A    D P           T + + VSW+PP    
Sbjct: 13084 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 13143

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
              + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A+      +P
Sbjct: 13144 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 13201



 Score =  125 bits (314), Expect = 5e-28
 Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 14214 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14272

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 14273 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14320

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 14321 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14378

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 14379 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14435

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 14436 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14489

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 14490 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14549

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 14550 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14608

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 14609 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14666

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 14667 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14726

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 14727 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14786

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 14787 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14846

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
               T   L+ GLEY   V           I+   I A     VP PP   + T +  D+M 
Sbjct: 14847 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14904

Query: 1285  VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
             ++W  P S   +  L  +   K    +   ++S +    N    + L  G  Y   V + 
Sbjct: 14905 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 14964

Query: 1342  YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
                 +S P +  +       +D P      +IT ++ T+ W  P  T    IT Y +   
Sbjct: 14965 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15024

Query: 1394  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
                     + +      N  T++ LT    Y   ++A N        I   S  SD    
Sbjct: 15025 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 15080

Query: 1454  LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
              + V A    + + +    +      +R+    +G   P  E++  G +   T       
Sbjct: 15081 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15140

Query: 1512  VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
              D++  +           A T    +P        N +  +D+P      + VT+V    
Sbjct: 15141 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 15199

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
               + W P      + +  Y V     +    T   +     T++ +  L    EY+  V 
Sbjct: 15200 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 15258

Query: 1614  AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
             A N  G  +PL    V  +        P + + T +T  S+   W  P+     ++  Y 
Sbjct: 15259 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 15318

Query: 1664  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
             V    K     +K            VSGL    +YE  + A      S P+         
Sbjct: 15319 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15378

Query: 1719  TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
              T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P
Sbjct: 15379 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 15435

Query: 1774  DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
                    SYTITGL    +YKI +Y +N      P ++
Sbjct: 15436 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15473



 Score =  123 bits (308), Expect = 2e-27
 Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13112

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 13113 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13172

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13173 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13232

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13233 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13292

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13293 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13351

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13412 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13469

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13470 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13526

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13527 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13581

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 13582 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13638

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 13639 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13689

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 13690 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13746

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 13747 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13806

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 13807 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13866

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 13867 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13926

Query: 1563  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 13927 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13986

Query: 1623  PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
                ++  T I      APT +         L+ +     + L    +   P  K+   K 
Sbjct: 13987 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 14044

Query: 1677  ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
                       +I   P SS + +     AT+ +   Y +  T    ++     VT L+  
Sbjct: 14045 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 14101

Query: 1725  SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
              PP    +++ +    T++W    E         +    +T   +   +  D++S  +  
Sbjct: 14102 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 14161

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
             T L  G +Y   +  +N   +  PV  +    +D       P        T N+  VSW+
Sbjct: 14162 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 14221

Query: 1835  PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
              P     + ITGY ++  +  S       +         +TGL+ G+ Y   V A
Sbjct: 14222 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 14276



 Score =  120 bits (300), Expect = 2e-26
 Identities = 273/1236 (22%), Positives = 459/1236 (37%), Gaps = 166/1236 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20777

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20778 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20833

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20834 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20890

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20891 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20941

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 20942 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21000

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 21001 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21060

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 21061 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21116

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 21117 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21176

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 21177 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21233

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 21234 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21289

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 21290 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21348

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 21349 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21408

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 21409 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21468

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 21469 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21528

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T    +P   +
Sbjct: 21529 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 21587

Query: 1638  ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
                       +K  +        Q  P   ++T ++  V  +++     EI     S+S+
Sbjct: 21588 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 21644

Query: 1688  VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
              V     AT+    VY ++    S  A+  +      +P +     R T+ T   +T+ W
Sbjct: 21645 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21701

Query: 1745  RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
                       IT + ++    +         K + +SYT   L  G +Y+  +  +N   
Sbjct: 21702 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 21761

Query: 1799  ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
                   S PVV     T  DAP        T NS+ ++W  P     + I  YI+ + EK
Sbjct: 21762 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 21821

Query: 1850  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
               +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 21822 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 21857



 Score =  118 bits (295), Expect = 7e-26
 Identities = 345/1615 (21%), Positives = 576/1615 (35%), Gaps = 251/1615 (15%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 22587 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22645

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 22646 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22695

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 22696 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22751

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 22752 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22809

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 22810 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22860

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 22861 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22920

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 22921 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 22980

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 22981 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 23040

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 23041 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 23094

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 23095 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23154

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 23155 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23205

Query: 1222  EEVVHADQS-----SCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTIIPAVPP-- 1269
             E  + A ++     S T   +S  +E  +  + V  +      E    SD ++ +  P  
Sbjct: 23206 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23265

Query: 1270  PTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
             P  L   ++   T+ + W  P       LT +++       E  +  +++ P+     +T
Sbjct: 23266 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23325

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI-TANSFTVHWIAPRATI 1385
             +L  G +Y+  + +  E+  S P        +     +   D+ T    T+H  A R   
Sbjct: 23326 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVE 23385

Query: 1386  TGYRIRHHPE-----HFSGRPR--------EDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
                 I   P       F+G           E     ++ +I  T +    EY + +  + 
Sbjct: 23386 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 23445

Query: 1433  GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
             G     + +            +++     TS+ ISW+ P            E  G +P+ 
Sbjct: 23446 GTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP------------ELDGGAPLS 23493

Query: 1493  EFTV-------PG--------SKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI 1536
              + V       PG        ++ST   + L  G +Y   V A    G  S   S+ I  
Sbjct: 23494 GYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 23553

Query: 1537  NYRTEIDKPSQ-MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
                  I  P + +Q+ DV  + +++ W P      S VTGY V           +     
Sbjct: 23554 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 23613

Query: 1592  PDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA-PTDLKFTQVT 1644
                T     GL   +EY   V A N      PS  S+P+V       P  P + + T  T
Sbjct: 23614 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 23673

Query: 1645  PTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
              TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y  
Sbjct: 23674 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 23733

Query: 1701  SVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTE 1749
              V A        PA+  G V   E +  P             V       +TI  + K  
Sbjct: 23734 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP- 23792

Query: 1750  TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVI 1807
                 F +      GQ   +R +     ++T   ++     D   Y   L +      V I
Sbjct: 23793 ----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 23848

Query: 1808  DASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVV 1858
                  I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    + 
Sbjct: 23849 KVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTID 23907

Query: 1859  PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA------------- 1905
              R R   T   + GL+   EY   V A      S+PL   +    +              
Sbjct: 23908 SRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPE 23965

Query: 1906  -----LSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 1955
                   S  ++SW+  +D      + Y I      TD+     +   T+T  T+TGL   
Sbjct: 23966 VLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPD 24025

Query: 1956  ATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2012
             A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V  +WE
Sbjct: 24026 AEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWE 24080

Query: 2013  RMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2067
             +    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 24081 KPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24127



 Score =  117 bits (294), Expect = 9e-26
 Identities = 153/711 (21%), Positives = 271/711 (38%), Gaps = 74/711 (10%)

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
             PP   ++   I   ++ ++W PP       L+ ++V      +      +S S + +   
Sbjct: 23462 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 23520

Query: 1325  LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              T L  G EYV  V++        Y Q E    R   +     P  +   D++ +  T+ 
Sbjct: 23521 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 23579

Query: 1378  WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
             W  P     + +TGY +           R ++VP +      T LT G EY   + A+N 
Sbjct: 23580 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23639

Query: 1434  R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
             R          P++          P++  V   T TS+ ++W  P       V  Y I  
Sbjct: 23640 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 23699

Query: 1483  GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
              +   +   +  T P      T++ L  G +Y   V A    G    +  P ++     +
Sbjct: 23700 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23759

Query: 1543  DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
             + P   ++ +     I V+    +  + P+ G  + +    K G   +K       +T  
Sbjct: 23760 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 23818

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
             E+ I+           +  +N  G+    ++  V   P   +  L++  +   S+   W 
Sbjct: 23819 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23878

Query: 1654  PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
             PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A   
Sbjct: 23879 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 23935

Query: 1708  TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
                S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ ++
Sbjct: 23936 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 23995

Query: 1758  AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
                 +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  D
Sbjct: 23996 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24054

Query: 1809  ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
                    P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R  
Sbjct: 24055 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 24114

Query: 1865  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAP 1915
               + TI GL   TEY   V A      S P    ++T     ++ T   AP
Sbjct: 24115 DKQFTIGGLLEATEYEFRVFAENETGLSRP----RRTAMSIKTKLTSGEAP 24161



 Score =  116 bits (291), Expect = 2e-25
 Identities = 283/1346 (21%), Positives = 478/1346 (35%), Gaps = 213/1346 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17781

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17782 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17828

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17829 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17884

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17885 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17944

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 17945 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18003

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18056

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 18057 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18115

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18233

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 18234 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18287

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 18288 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18347

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAV-PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 18407 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18465

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 18466 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18645

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 18646 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18693

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 18694 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18749

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 18750 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18806

Query: 1613  YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
               +N SG     V   V   P AP +L   +V   S++  W PP      ++T Y   + 
Sbjct: 18807 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 18863

Query: 1668  PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
              K +T       +  + +     +  L     Y   V A  +     PA+    V   E 
Sbjct: 18864 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 18923

Query: 1724  VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
               PP R  + D T  T TI W  K E+     ITG+ V+ +   G        +      
Sbjct: 18924 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 18981

Query: 1779  TITGLQPGTDYKIYLYTLNDNARSSP 1804
             TI+GL  G +Y   +  +N+  RS P
Sbjct: 18982 TISGLTAGEEYVFRVAAVNEKGRSDP 19007



 Score =  115 bits (289), Expect = 4e-25
 Identities = 310/1459 (21%), Positives = 503/1459 (34%), Gaps = 214/1459 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 18400 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18454

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 18455 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18512

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 18513 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18571

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 18572 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 18625

Query: 905   DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 18626 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18685

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
             L G+              VT L     Y F++ A++     +P T      AQ+  +   
Sbjct: 18686 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18734

Query: 997   --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
               LDA      V    +T+ +  T    P  ++   +    LT R Q     V  S +  
Sbjct: 18735 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 18791

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 18792 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18851

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 18852 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18967

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
             ++ ++  +V   +    T   L+ G EY   V  V +   S P  +   +I     + P 
Sbjct: 18968 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 19024

Query: 1271  TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
              +L F               P        V +              V + + V  LSI  
Sbjct: 19025 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 19084

Query: 1319  SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
             +    V      GT  +   +S         +    + G   P  ID  +++ +S T+ W
Sbjct: 19085 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 19136

Query: 1379  IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
               P       I+ Y I    E  S          +R SI +  LT G+EY   + A N  
Sbjct: 19137 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19195

Query: 1434  -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
                   E S ++     +    P   +VV AT +++L++W  P       V  Y + Y E
Sbjct: 19196 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19255

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
                    +   +  + +   +SGL  G+ Y   VYA  + G G    S +P+    R   
Sbjct: 19256 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 19313

Query: 1543  DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
             D P Q +VT++   S+S+KW        + +TGY V           K       +T   
Sbjct: 19314 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19373

Query: 1599  IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
             +  L     Y   V+A+N       PS  + P +V+  V       D+KF  V     + 
Sbjct: 19374 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 19432

Query: 1651  QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
             +    N  + G  + V    K G   E       ++ D+ +++     +       V  L
Sbjct: 19433 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19492

Query: 1706  KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
             K+   +R        L+   PP     +   T    ++SW    E   G  +D   V   
Sbjct: 19493 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 19551

Query: 1763  GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
               + +  TI   +  + S  +T L  G +Y   +  +N      P+       +D  T  
Sbjct: 19552 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19611

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               P++L   + T  S+ + W  P     + I+GYII+  +  S     V +         
Sbjct: 19612 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19671

Query: 1870  ITGLEPGTEYTIYVIA-----LKNNQKSEPLI------------GRKKTGQEALSQTTIS 1912
              TGL  G EY   V A     L    ++ PLI             + K      +  TI+
Sbjct: 19672 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIA 19731

Query: 1913  WA-PFQDTSEYIISCHPVGTDEEPLQFRVPGTS---TSATLTGLTRGATYNIIVEAL--- 1965
             W  P  D    I          +   ++    S   T  T++GLT GA Y   V+++   
Sbjct: 19732 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 19791

Query: 1966  --------KDQQRHKVREE 1976
                      D Q  K REE
Sbjct: 19792 GASDPSDSSDPQIAKEREE 19810



 Score =  115 bits (288), Expect = 5e-25
 Identities = 283/1405 (20%), Positives = 509/1405 (36%), Gaps = 159/1405 (11%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18431 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18489

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18490 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18536

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18537 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18595

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18596 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18655

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18656 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18715

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 18716 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18775

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 18776 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18832

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 18833 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18892

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 18893 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 18949

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 18950 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19009

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 19010 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19062

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAVPPPTDL 1273
             L+E    + SS    T  ++    + +V  Y +         +VPI+  ++    PP  +
Sbjct: 19063 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 19122

Query: 1274  RFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTN 1327
             R   +  D++ ++W PP       ++N++V     K E        +S + +  ++ +  
Sbjct: 19123 RIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVR 19178

Query: 1328  LLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP 1381
             L  G+EY   V +          ES+ +          P G       T ++  V W  P
Sbjct: 19179 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19238

Query: 1382  ----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----G 1433
                  + + GY + +         + +++  +   + ++ L  G  Y   + A N    G
Sbjct: 19239 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19298

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             +              D P   EV   T  S+ + W  P       +  Y +   E     
Sbjct: 19299 KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGR 19358

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQM 1548
              ++       ++   ++ L     Y   V+A       S  S     I  + +++ P  M
Sbjct: 19359 WLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVM 19418

Query: 1549  QVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIE 1600
                  +D  +  + + L  ++ + G    V +  K+G       +T+    D  T +T++
Sbjct: 19419 MDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK 19478

Query: 1601  GL--QPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT--DLKFTQVTPTSLSAQWTPP- 1655
                 + T +YV+++  +N +G     V   V   P P    L+   +T    S  W  P 
Sbjct: 19479 DCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 19536

Query: 1656  ---NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLT 1710
                   +  Y   +  K +T  +       +   +S  V+ L+   +Y   V  +     
Sbjct: 19537 EDGGADIDYY---IVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 19593

Query: 1711  SRPAQGV-VTTLENV---SPPRRARVTDATETTITISW-RTKTE---TITGFQVDAVPAN 1762
               P + V +  L+     SPP    +T  T+ ++T+ W R +++    I+G+ ++    N
Sbjct: 19594 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19653

Query: 1763  GQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAI--- 1813
                 ++   KP  D+R  + TGL+ G +Y+  +Y  N    S P     +I A   +   
Sbjct: 19654 SLRWVRVNKKPVYDLRVKS-TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19712

Query: 1814  DAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               PS  + + +   ++ ++W  P     A ITGY ++Y+K      +   +   G TE T
Sbjct: 19713 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 19771

Query: 1870  ITGLEPGTEYTIYVIALKNNQKSEP 1894
             I+GL  G EY   V ++     S+P
Sbjct: 19772 ISGLTTGAEYVFRVKSVNKVGASDP 19796



 Score =  112 bits (281), Expect = 3e-24
 Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 14101 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14155

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 14156 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14202

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 14203 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14262

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 14263 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14322

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 14323 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14381

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 14382 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14441

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 14442 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14498

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 14499 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14557

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 14558 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14616

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 14617 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14675

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 14676 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14732

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 14733 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14792

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 14793 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14851

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 14852 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14911

Query: 1383  AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
             +     I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 14912 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14971

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 14972 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15028

Query: 1492  QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +      +      T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 15029 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15088

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 15089 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15141

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
                  +             ++ A NP G ++ +    V   P P +  L  T+VT     
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15201

Query: 1650  AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
               W PP      ++  Y V+   K +T  +   N+A +   + + V+ L+   +Y     
Sbjct: 15202 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 15258

Query: 1699  EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
              V+ Y + + L S P   V        PP+   VT  T+ ++ + W           ++ 
Sbjct: 15259 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15317

Query: 1759  VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
             +        QR IK + ++     Y ++GL  G +Y+  +   N    S+P         
Sbjct: 15318 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 15377

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
              D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V  P 
Sbjct: 15378 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 15437

Query: 1863  P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
                 T  TITGL    EY I + A+ +    EP +
Sbjct: 15438 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15472



 Score =  110 bits (275), Expect = 2e-23
 Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)

Query: 709   NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
             N V     P  P+     S  E+T    V+SW    D   G ++   + E+ +  + + +
Sbjct: 10535 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 10588

Query: 769   PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
             P T+    T+  +  LL G+ YI      N+Y IS+      + +  +   PDAP  P V
Sbjct: 10589 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 10648

Query: 820   DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
              +V   S +V W++P     PIT Y +    ++      +            + DL  G 
Sbjct: 10649 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 10708

Query: 875   QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             QY   + A  E     P    +             P + + ++ T   V + W PP    
Sbjct: 10709 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 10768

Query: 932   -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
              S + GY V+   V +         P S   T  +VTGL  G TY F+V AV+   ES P
Sbjct: 10769 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 10828

Query: 989   LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
                 +      +L+ P  +   N      +      R  A I G    ++T     R  P
Sbjct: 10829 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 10888

Query: 1040  RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
              +   +V P  SK  +RN         SL           +  V    +PG   PP + E
Sbjct: 10889 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 10945

Query: 1098  VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
             V+E    +  +TW      G      + +  R     + +P   TS   S     L  G 
Sbjct: 10946 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 11005

Query: 1148  EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
             +Y++  +V  + Q    P V      K + PL    PP +LH   + D   +++ W   +
Sbjct: 11006 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 11062

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
             R     ITGY +       Q     + V + +   C    L  G  Y   V    ++   
Sbjct: 11063 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 11117

Query: 1257  VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
             + + DT IP       VPP  +L    I         T+R    +   P P+   T    
Sbjct: 11118 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 11174

Query: 1301  RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
               S +K +E     + + S    +   L   T EY ++VS+       +       T LD
Sbjct: 11175 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 11230

Query: 1360  ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
                 PTG I+  D+T    T+ W  P+       I +  E    R     V  S +S T 
Sbjct: 11231 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11290

Query: 1415  --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
               + +L  G EYV  + A N        + +P +   + +    P    V   T  +  +
Sbjct: 11291 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11350

Query: 1467  SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             SW  P     +    YY      TG    V +  +   K   T  GL  G  Y   V+A 
Sbjct: 11351 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 11408

Query: 1522  TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
                G S  S     I     I  P      ++ D    +  + W        SP+ GY V
Sbjct: 11409 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 11468

Query: 1575  TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
                    PG  +      D    Q    + GL    EY   + A N  GE +P  L ++ 
Sbjct: 11469 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 11525

Query: 1629  VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
             +   I  P +++   VT   +        +++   RV+  P+      K G +    K +
Sbjct: 11526 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 11583

Query: 1679  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
             +L  D   V +  +  A + +   Y +    +S  AQG  +V  L+   P +  +VT+ T
Sbjct: 11584 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11642

Query: 1737  ETTITISWRTKTET----ITGFQVD 1757
             +   TISW    +     IT F V+
Sbjct: 11643 KENCTISWENPLDNGGSEITNFIVE 11667



 Score =  110 bits (274), Expect = 2e-23
 Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
            +T++T  S +++W    D        Y +     D   +  L ST    N     L+P +
Sbjct: 7420 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 7479

Query: 785  KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
            +YI      N+Y + E  + S I +  Q   P  P       +   ++ + W  P     
Sbjct: 7480 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7539

Query: 836  APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
            +PITGY +    P  +       +P    +  +  L    +Y   + A       +  +S
Sbjct: 7540 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7599

Query: 890  TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
            T  ++ ++    P     P+ +D     V    V + WT PE    + +  Y ++++   
Sbjct: 7600 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7654

Query: 946  LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
                    + +P +++    + GL  G  Y F+V AV+   ES+P       L  ++   
Sbjct: 7655 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7711

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
               P  L+ +N T +T  ++WT P     + IT Y +     RR   +  +     +K  
Sbjct: 7712 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7771

Query: 1053 LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
            +  L   S Y   + A            ++S  A   FTT  PG   PPY   V + T  
Sbjct: 7772 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 7826

Query: 1103 -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
             + + W P    G +            LG R  + G+          +  V+ +  G E 
Sbjct: 7827 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 7882

Query: 1150 VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
             + ++   +       +  +   +    +P SPP +LH+    D G   + ++W   E++
Sbjct: 7883 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 7939

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                I GY +   P   ++   +      D      + + P  EY + V  V     S P
Sbjct: 7940 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7999

Query: 1259 --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
              IS+ ++   P   P  DL   +I          P   R    P  S       V+ S 
Sbjct: 8000 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 8059

Query: 1305 ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
               +KN+   A L +  S  A      + L N L      ++V  +              
Sbjct: 8060 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 8105

Query: 1356 TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
             GL  P   I  SDIT +S  + W  P     G  I H+        R   +P     ++
Sbjct: 8106 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 8163

Query: 1411 NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
             S T+ +L P  EY   + A+N   G E    ++P++        D P D+EV   T  +
Sbjct: 8164 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 8223

Query: 1464 LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
            + I+W  P       +  Y   +I  GE        E  VP    T T  GL+ G +Y  
Sbjct: 8224 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 8280

Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
             V A    G S  S           ID P  +  T ++         D SIS      + 
Sbjct: 8281 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 8340

Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
            W+   + +    +    K    P   +  G  Q E                         
Sbjct: 8341 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8396

Query: 1600 -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
             + L+P    +  +  +N  G ++ P   + + T   P +  F  +  TS+  +W PP  
Sbjct: 8397 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 8455

Query: 1656 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
                ++  Y +    K K          PDS  +VV+  +   KY V+       Y  + 
Sbjct: 8456 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 8505

Query: 1708 TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
               +R   G   V   L    P      P +  V D T  ++ + W    +    I G+ 
Sbjct: 8506 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 8565

Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
            ++    N    + + +++   +++  + GL  G  Y   +   N     + SP   D  T
Sbjct: 8566 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 8623

Query: 1812 AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
            A D      P   R   T+  ++ + W+PP       I GY +  +  G+          
Sbjct: 8624 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8683

Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
              V + T+  +  G +Y + V A+    +  P
Sbjct: 8684 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 8715



 Score =  109 bits (273), Expect = 3e-23
 Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6673 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6732

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6733 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6791

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6792 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6851

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6852 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6911

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6912 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6969

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 6970 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7028

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 7029 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7088

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 7089 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7143

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
               +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 7144 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201

Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7261

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
             VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 7262 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7315

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                  V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 7316 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7372

Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
            +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 7373 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7432

Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 7433 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7485

Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
             A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 7486 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7545

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
             V     +     +        T   ++GL    +Y   V A+N +G  +P   T    I
Sbjct: 7546 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7605

Query: 1633 PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
              P D  +    P       TS+   WT P      ++  Y + +    KTG  + + +A
Sbjct: 7606 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 7662

Query: 1682 P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
                ++  ++ GLM   +Y   V A+     S P++    V   E +   SPPR   V +
Sbjct: 7663 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7722

Query: 1735 ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
             T+ T  + W    +     IT + V+   V   G   +  T+K      T+T L  G+ 
Sbjct: 7723 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 7780

Query: 1789 YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
            Y   +   N   +S       S +  D  T    P  L  +  T   + + W+PP+
Sbjct: 7781 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 7836



 Score =  109 bits (273), Expect = 3e-23
 Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)

Query: 692   VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
             VTRFD    S    +T    +G  T F       SP    + ++ E+   S  +SW    
Sbjct: 18796 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18851

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
             +     ++ + VE     E     Y  + +  T T+  I +L  G  Y   V   +E G 
Sbjct: 18852 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908

Query: 799   QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
               L   T++      PP P    T+  V   +  ++W +P++     ITGY  V     +
Sbjct: 18909 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 18965

Query: 851   GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
             GS       +      T+S L  G +Y   + AV E   S P      VI ++    P  
Sbjct: 18966 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 19023

Query: 905   DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
              +V  P     V+  + +K+ + +     A   +R D          GQ L     ++ +
Sbjct: 19024 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 19072

Query: 960   TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
             +   VT LS        V  Y    + S G  + P+T     +   P  ++    +  ++
Sbjct: 19073 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19132

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
              + W PP      QI+ Y   V          + V  +V++  ++   L   SEY   + 
Sbjct: 19133 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19190

Query: 1068  AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
             A          ES      +    PG    P     T++T+++TW           IG+ 
Sbjct: 19191 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19250

Query: 1117  LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
             L  +        +A + + +D+  + VSGL  G+ Y   VY   +   G+   +      
Sbjct: 19251 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19309

Query: 1171  VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
               P  PP     TN+  ++        + D G     +  ER   PD  G  +    TN 
Sbjct: 19310 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 19367

Query: 1216  QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
             Q+       +  DQ       +    D++S   E +     VKDD E       V   D 
Sbjct: 19368 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 19426

Query: 1263  IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
             I+        +     G     ++WA    I++             E+ A   I  +DN 
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 19472

Query: 1323  VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
              +LT          +YV+++ +V      +   +   K G   P G ++ + +TA   ++
Sbjct: 19473 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 19530

Query: 1377  HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
              W  P+    A I  Y + +    H +    E  +     S  +T L  G EY+  +  +
Sbjct: 19531 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 19588

Query: 1432  NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
             N        E   +      TV   P  LE+ + T  S+ + W  P       +  Y I 
Sbjct: 19589 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19648

Query: 1482  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
               E      V+    P        +GL+ G +Y   VYA    G S P+ + P+ I    
Sbjct: 19649 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 19707

Query: 1541  EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
              +     PS+ ++ D    +I++ W+       +P+TGY V    K+     KT      
Sbjct: 19708 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 19766

Query: 1594  QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
              TE TI GL    EYV  V + N      PS  S P +       P     ++++ T + 
Sbjct: 19767 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 19826

Query: 1645  PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
                 S   T P      +R R  P           +T    +   +  S ++  +    +
Sbjct: 19827 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 19880

Query: 1696  TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
              KY +++   ++ L++     VV  L+   PP    V D T+ +  +SW          +
Sbjct: 19881 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 19937

Query: 1752  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
               + ++   A+ +  +  T   +  SY +T LQ G  Y   +   N+     P       
Sbjct: 19938 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 19997

Query: 1812  AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
              I      P  L   + + +S+ ++W  P     +RI  Y+++  + G   +  V     
Sbjct: 19998 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 20055

Query: 1864  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
               T   ++GL   +EY   V A      S+P
Sbjct: 20056 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20086



 Score =  108 bits (271), Expect = 4e-23
 Identities = 280/1299 (21%), Positives = 479/1299 (36%), Gaps = 170/1299 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15191 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15308

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15309 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15367

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15424

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15425 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15484

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15485 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15535

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15536 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15595

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15596 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15652

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15653 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15710

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15711 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15767

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 15768 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15821

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 15822 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15879

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 15880 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15938

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 15939 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15997

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 15998 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16057

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 16058 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16117

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
                   T   + GL     Y   V A+N +G  S+P   T   T     D         S
Sbjct: 16118 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 16172

Query: 1648  LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
             +  ++    V   G   +V       P+  I          +++ + +     AT   V 
Sbjct: 16173 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 16232

Query: 1702  ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
                       +   K+    R     V  L+   PP     ++  T    T++W+   + 
Sbjct: 16233 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 16292

Query: 1751  ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
                  ++ +    +T   +   +  +V+  S  +T L  G +Y   +     Y + +   
Sbjct: 16293 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 16352

Query: 1802  SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
             S PVV      + DAP        T +S++V W+ P     + I GY++ K +K G    
Sbjct: 16353 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 16412

Query: 1856  EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 R   G     +TGL    +Y   V A      SEP
Sbjct: 16413 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16450



 Score =  105 bits (261), Expect = 6e-22
 Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 9857  VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9916

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 9917  FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9976

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 9977  TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10034

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 10035 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10094

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 10095 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10154

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 10155 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10208

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 10209 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10268

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 10269 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10328

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 10329 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10387

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 10388 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10444

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
             PPT          +R       T R +  P P +         S  K+E DV E     +
Sbjct: 10445 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10495

Query: 1315  SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
               +P+  A+          G   VV  +S   +     +    + G   P G + F ++T
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 10553

Query: 1371  ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
              +   + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+ 
Sbjct: 10554 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 10612

Query: 1427  SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
              I A N    S  L+           V D P    V   T  S L++W+ P         
Sbjct: 10613 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 10672

Query: 1472  -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
                     ++ R+ R+T        P  +F VP          L  G  Y   V A    
Sbjct: 10673 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 10720

Query: 1523  GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
             G GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY + 
Sbjct: 10721 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 10777

Query: 1576  TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
                K G    +     P+   +T+  + GL+    Y   V A N +GES P        +
Sbjct: 10778 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 10831

Query: 1633  PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
             P P  +K     P   L A          G  +R++      P  K    KE   AP  +
Sbjct: 10832 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10891

Query: 1686  SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
              + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR   V++ 
Sbjct: 10892 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 10949

Query: 1736  TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
              + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    L  G  Y
Sbjct: 10950 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 11007

Query: 1790  KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
                +   N   R   V        +D       P +L  +      + + W  P     +
Sbjct: 11008 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 11067

Query: 1839  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
              ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K+E ++G
Sbjct: 11068 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 11117



 Score =  103 bits (257), Expect = 2e-21
 Identities = 257/1326 (19%), Positives = 466/1326 (35%), Gaps = 204/1326 (15%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 13000 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 13059

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 13060 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 13117

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 13118 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13176

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 13177 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13236

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 13237 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13296

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 13297 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13349

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 13350 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13407

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 13408 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13462

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPAVPPPTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 13463 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13518

Query: 1274  RFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
             +  ++   +  + W  P S     +  ++V +   +N+      S+S   +A  LT    
Sbjct: 13519 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE--- 13575

Query: 1331  GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI----T 1386
             G EY   VS+  E  E TP            T +   D+ A    +  +     +    +
Sbjct: 13576 GKEYTFRVSAENENGEGTP---------SEITVVARDDVVAPDLDLKGLPDLCYLAKENS 13626

Query: 1387  GYRIR-----HHPEHFSGRPRED------RVPHSRNSITLTNL------TPGTEYVVSIV 1429
              +R++           S +  ED      RV    +++  T +      +   +Y +++ 
Sbjct: 13627 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 13686

Query: 1430  ALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1485
              + G +E  + I            ++    T  ++ + W  P       +  Y +   ++
Sbjct: 13687 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13746

Query: 1486  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTEI-D 1543
               N  V   +    K+T  ++ L  G++YT  V A    G      S+PI   +  ++ D
Sbjct: 13747 VNNKWVTCASAV-QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13805

Query: 1544  KPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1599
              P    + DV+ +S+S+ W        SP+TGY +    +N     +         +  +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
              GL   +EY   V A N +G  +P + +    A+  I  P   +   +T  S++  WT P
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP 13925

Query: 1656  NV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL-- 1709
                   +LTGY V          MK  ++     +  V+ L+   KYE  + A K+T   
Sbjct: 13926 KYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRA-KNTAGA 13984

Query: 1710  TSRPAQGVVTTLEN---------VSPPRRARVTDATETTITI-------------SWRTK 1747
              S P++   T +           + P  +  +T     TI +             SW   
Sbjct: 13985 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 14044

Query: 1748  TETITGF---QVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYLYTLNDNARSS 1803
              + I      Q+ + P +    I+   + D   YTIT   P GT  +    T+ D     
Sbjct: 14045 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLD----- 14099

Query: 1804  PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1859
                         P  +     +     ++W PP     + I  YI++  +       VV 
Sbjct: 14100 --------VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS 14151

Query: 1860  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG----------------RKKTGQ 1903
                        T L  G EY   V A+ +  K EP+                  + +   
Sbjct: 14152 EDIQSCRHVA-TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSN 14210

Query: 1904  EALSQTTISWA-PFQDTSEYIISCHPVGTDEEPLQF----RVPGTSTSATLTGLTRGATY 1958
                +  T+SW  P  D    I   H    +++ L++    + P +     +TGL  G+TY
Sbjct: 14211 VTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTY 14270

Query: 1959  NIIVEA 1964
                V A
Sbjct: 14271 EFRVSA 14276



 Score =  102 bits (255), Expect = 3e-21
 Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10263 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10321

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10322 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10369

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10370 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10429

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10430 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10490 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10547

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10548 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10603

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10604 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10663

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10664 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10723

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 10724 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10781

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 10782 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10841

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 10842 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10900

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 10901 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10946

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 10947 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11005

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 11006 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11064

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 11065 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11122

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 11123 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11174

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 11175 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11226

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 11227 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11283

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T        + P+P      T +
Sbjct: 11284 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11343

Query: 1644  TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
             T  + +  WT P       +TGY +    +E TG    +N  P +     V+GL     Y
Sbjct: 11344 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 11401

Query: 1699  EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
             E  V+A      S+P+           ++   PP   ++ D +  T  + W TK      
Sbjct: 11402 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 11460

Query: 1749  ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
               I G+ V+     G     R  K ++    ++ + GL  G +Y+  +   N      P
Sbjct: 11461 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11518



 Score =  101 bits (252), Expect = 7e-21
 Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21794 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21852

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21853 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21900

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21901 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21960

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 21961 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22020

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 22021 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22079

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 22080 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22135

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22136 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22194

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22195 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22252

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22253 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22307

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22308 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22367

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22368 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22427

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 22428 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22484

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 22485 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22543

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22601

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 22602 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22659

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 22660 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22719

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 22720 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22776

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 22777 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22824

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
             + YVV+           V A N  G     ES+P+V     TIP+P  +     T    +
Sbjct: 22825 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22884

Query: 1649  SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
               QWT P      +++ Y V    K +   ++   +  D     + + V+ LM    Y+ 
Sbjct: 22885 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 22941

Query: 1701  SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
              V A+     S P  A   ++  E      PP   RV D T+ +I+++W
Sbjct: 22942 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 22990



 Score =  101 bits (251), Expect = 9e-21
 Identities = 274/1343 (20%), Positives = 479/1343 (35%), Gaps = 185/1343 (13%)

Query: 692   VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
             V R+D   +T T  ++  T +         +P    +  VTEIT  S  ++W    +   
Sbjct: 16631 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 16690

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
               +  + VE     E     Y  + +     S  I  L  G  Y   V   +E G     
Sbjct: 16691 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 16747

Query: 803   LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
              +       + P  P   TVD V   S+ + W++P+       I Y   ++   +E    
Sbjct: 16748 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 16806

Query: 860   ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
             E A        +++L  G +Y   + AV E   S P           +VI+ +      S
Sbjct: 16807 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16866

Query: 905   DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
              +V   +DL+ +EV      K TI WT           D +P+       Q   I+    
Sbjct: 16867 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 16909

Query: 962   AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
              ++T LS   T+      Y    A   G+++  +      K D P   ++F + +  ++ 
Sbjct: 16910 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 16969

Query: 1015  VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
             + W PP      QIT Y +    T        +   + +   +  L+  +EY   + A  
Sbjct: 16970 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 17029

Query: 1071  --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
               G     ES      +   +PG    P+ T +++ ++VI W        +P IG+ L  
Sbjct: 17030 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 17089

Query: 1120  RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
             +        +  + +  D+       L  G+EY + +       V +  +  +  +    
Sbjct: 17090 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 17148

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
               P   P  + ++ N     +T+ W +        ITGY +     P       S   V+
Sbjct: 17149 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17204

Query: 1226  HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
                ++  T   L+    Y   V          K    + PI+   +  +P +   P   D
Sbjct: 17205 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 17261

Query: 1273  LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
                 N G +T R    V   P P+I+           K  E+ A   I  +D   +L   
Sbjct: 17262 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 17314

Query: 1326  -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
                 + G +Y++  S+V    +S P+  +       P G +  + +T+   ++ W +P  
Sbjct: 17315 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 17372

Query: 1384  TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALN------G 1433
                G  I H+   +  + R     V      NS+ +T L  G EYV  I+A+N       
Sbjct: 17373 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17432

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
              E +P+L+     +   P+ LEV      S+ + W+ P        I Y  E    S ++
Sbjct: 17433 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 17492

Query: 1493  EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
                    + T     ++GL    +Y   V A    G    S  P ++ Y+      +   
Sbjct: 17493 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 17550

Query: 1545  PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN-GPGPTKTKTAGPDQTEMTI 1599
             P+   + D   NSI++ W        S + GY V     +       T   G   T   I
Sbjct: 17551 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 17610

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
               L    EY + V A N  G  +    T+V     P D    +     L ++     V  
Sbjct: 17611 SKLTEHQEYKIRVCALNKVGLGE---ATSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 17665

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
              G   R+    K  P  EI  + +    +  V +   +  T+  +           +  L
Sbjct: 17666 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 17725

Query: 1706  KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
             +++  S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +
Sbjct: 17726 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 17785

Query: 1762  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
               +     + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS   
Sbjct: 17786 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 17845

Query: 1818  NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1873
              +     +  S  + W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL
Sbjct: 17846 KVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGL 17903

Query: 1874  EPGTEYTIYVIALKNNQKSEPLI 1896
               G EY   V A     KS+P +
Sbjct: 17904 SSGQEYQFRVKAYNEKGKSDPRV 17926



 Score =  100 bits (250), Expect = 1e-20
 Identities = 283/1422 (19%), Positives = 504/1422 (35%), Gaps = 178/1422 (12%)

Query: 609   SGPVEVFITETPSQPNSHPI-----------QWNAPQPS---HISKYILRWRPKNSVGRW 654
             S P E  +   P  P   P+           +W  P+ +    I+ YI+  R   + GRW
Sbjct: 14973 SKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPN-GRW 15031

Query: 655   KEATIPGHL-NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
              +A     L N +T+ GL     YE ++I+    G           +  S P  S+ +T 
Sbjct: 15032 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG---------AISPPSEP--SDAITC 15080

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ---YLDLPS 770
                  +P +       +        ++   +D         E S++G E +    L++  
Sbjct: 15081 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15140

Query: 771   TATSVNIPDLLPGRKY--IVNVYQISEDGEQSLILSTSQTTAPDAPPDP-TVDQVDDTSI 827
                S N+ +    R+      +   +  G    I +      P  P  P  V +V     
Sbjct: 15141 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKC 15200

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             V+ W  P     A I  Y +    +   + T +        + ++ L  G +Y   + AV
Sbjct: 15201 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15260

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              +     P+  +      P     P P++ +   +T   + + W  P+S      ++ I 
Sbjct: 15261 NKYGVGEPLESEPVLAVNPYGPPDP-PKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI- 15318

Query: 944   VNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYFKVFAVSHGRESKPL-------TA 991
             V    + GQR +  ++ T  +    V+GL+ G  Y F++ A +    S P          
Sbjct: 15319 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15378

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYN--VG 1045
                 K   P N + ++ + S++ + W  P     ++ITGY + + L    + +      G
Sbjct: 15379 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG 15438

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
                + Y +  L    EY + + A+        A    T       +PP      +   V+
Sbjct: 15439 LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVV 15498

Query: 1106  T--------------WTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
             T                PAP + +      S   +A  E TS    ++V  +       Y
Sbjct: 15499 TIRACCTLRLFVPIKGRPAPEVKWARDHGESLD-KASIESTSSYTLLIVGNVNRFDSGKY 15557

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRI 1208
              + V      + A +  +V+    PP +L ++    T V T++W+         I  Y +
Sbjct: 15558 ILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV-TLTWDPPLLDGGSKIKNYIV 15616

Query: 1209  TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPIS 1260
                 +  +  +++    H  ++S   D L  G  Y   V    +          ESV  S
Sbjct: 15617 EKRESTRKAYSTVATNCH--KTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 15674

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSIS 1317
             +  +P    P  +   ++  +++ ++W  P       +  ++V      +++     ++ 
Sbjct: 15675 ERPLP----PGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVK 15730

Query: 1318  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              ++    +T L+ G EY   VS+  E+  S P +                 +  N+FTV 
Sbjct: 15731 VTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV- 15787

Query: 1378  WIAPRATITGYRIRHHPEHFSGRP------REDRVP----------HSRNSITLTNLTPG 1421
                    + G  ++     F GRP       +D VP           + N+  LT     
Sbjct: 15788 -------LAGEDLKVDVP-FIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDAC 15839

Query: 1422  TE----YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV---- 1473
              E    YVV +    G     L +            +++   T  S+ +SW  P      
Sbjct: 15840 REDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGS 15899

Query: 1474  TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP-ASSK 1532
             ++  Y +   +T   +  Q  +   +++T     LK G +Y   + A    G S   +S+
Sbjct: 15900 SINNYIVEKRDTS-TTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 15958

Query: 1533  PISINYRTEIDKPSQMQVTDVQD-NSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKT 1587
             P    Y  ++  P    V  +   +S+ V+W        S V GY +    +N     K 
Sbjct: 15959 PTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKL 16018

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL----KFTQV 1643
                   QT+    GL+  VEY   V A+N  G  +P   +       P D     +   V
Sbjct: 16019 NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV 16078

Query: 1644  TPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699
             T  S++ QW  P      ++TGY V      +   MK        +   V+GL+   +YE
Sbjct: 16079 TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYE 16138

Query: 1700  VSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
               V A     + S P++  G +T  + V PPR +      +T +  +  +       F+V
Sbjct: 16139 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES-------FKV 16191

Query: 1757  DAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SSPVVIDASTAI 1813
             DA       P  + IK D        L+   TD+   L ++ D  R  S   ++ A    
Sbjct: 16192 DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSGNYILKAKNVA 16250

Query: 1814  DAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSP 1853
                S   N++ L               T     ++W+PP     + I  YI++  +    
Sbjct: 16251 GERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRL 16310

Query: 1854  PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
                VV           +T L  G EYT  ++A+      EPL
Sbjct: 16311 VWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 16351



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 336/1557 (21%), Positives = 550/1557 (35%), Gaps = 260/1557 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 9926  GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 9980

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 9981  LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 10036

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 10037 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 10084

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 10085 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10142

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 10143 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10199

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 10200 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10252

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 10253 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10311

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 10312 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10371

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKGNQESP 1076
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G Q  P
Sbjct: 10372 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG-QGKP 10430

Query: 1077  KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT---- 1132
                    T +   + P  + +  +   +       R+G    +     G+   +V+    
Sbjct: 10431 SFCTKPITCKDELAPPTLHLDFRDKLTI-------RVGEAFALTGRYSGKPKPKVSWFKD 10483

Query: 1133  ------SDSGSIVVSGLTPGVEYV---------YTIQVLRDGQERDAPIVNKVVTPLSPP 1177
                    D   I  +  T  +E +         Y + V      R       VV    PP
Sbjct: 10484 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPP 10543

Query: 1178  TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS---LEEVVHADQSSCTF 1234
                          + +SW+     D  G +IT      ++      +     + +++C  
Sbjct: 10544 VGPVSFDEVTKDYMVISWKPPL--DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKV 10601

Query: 1235  DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VPPPTDLRF-TNIGPDTMRVTWA 1288
               L  G +Y   ++       S P+    + A     VP   D    T +  D+  VTW 
Sbjct: 10602 SKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWN 10661

Query: 1289  PPPS--IDLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE- 1343
              P      +TN+++  R +  K    V +  I P     V  +LL G +Y   VS+  E 
Sbjct: 10662 KPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRV-PDLLEGCQYEFRVSAENEI 10720

Query: 1344  -----QHESTPLRGRQKTGLDSP-TGIDFSDITANSFTVHWIAPR----ATITGYRIRHH 1393
                     S P+  +      SP    +  D T NS  + W  PR    + I GY + + 
Sbjct: 10721 GIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQ 10780

Query: 1394  PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGREES-------PLLIGQQ 1444
                     R +  P S       +T L  G  Y   ++A+N   ES       P+L+  +
Sbjct: 10781 KVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDR 10840

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVT--VRYYRITYGETGGNSPVQ---EFTVPGS 1499
                 ++  D  +       +  +    A+   V + ++T+ +   ++P +   + T  GS
Sbjct: 10841 LEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10900

Query: 1500  KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDN 1556
             K     +  + G  Y++TV       ++PA SK +S+     +DKP     ++V++++ +
Sbjct: 10901 KLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLV-LDKPGPPRDLEVSEIRKD 10952

Query: 1557  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             S  + W        S +T Y V          +        ++    + L    +Y+  V
Sbjct: 10953 SCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFA-KHLNEGNQYLFRV 11011

Query: 1613  YAQNPSGESQPLVQTAVTTIPA---------PTDLKFTQVTPTSLSAQWTPPNVQ----L 1659
              A+N  G   P V+T    I A         P DL    V  T +S  W  P+      +
Sbjct: 11012 AAENQYGRG-PFVETP-KPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPI 11069

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1717
             TGY V     ++ G    I     ++   VV+GL     Y   V A        P   + 
Sbjct: 11070 TGYLVEY---QEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 11126

Query: 1718  VTTLENVSPPRRARVTDATE-------TTI------------TISWRT---KTETITGFQ 1755
             +   E + PP         E       TT+            T  W T   + +T   + 
Sbjct: 11127 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11186

Query: 1756  VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1815
             V+    +    I+  ++ D   Y IT                 NA  S  V    T +D 
Sbjct: 11187 VETDNFSSVLTIKNCLRRDTGEYQITV---------------SNAAGSKTVAVHLTVLDV 11231

Query: 1816  PSN----LRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
             P      +  L  TP  + +SWQPP+    + +  YI++ +        VV       T+
Sbjct: 11232 PGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV-SSGSSKTK 11290

Query: 1868  ATITGLEPGTEYTIYV-----IALKNNQKSEPLIGRKK------TGQEALSQ-----TTI 1911
               I  L+ G EY   V     I +     S P + + K       G+  ++       T+
Sbjct: 11291 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11350

Query: 1912  SWA-PFQDTSEYIISCHPVGTDEEPLQFRV---PGTSTSATLTGLTRGATYNIIVEA 1964
             SW  P  D    I   +    +      RV   P       +TGL  G TY   V A
Sbjct: 11351 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFA 11407



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 18906 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18963

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 18964 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19014

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 19015 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19071

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 19072 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19128

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 19129 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19188

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 19189 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19242

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 19243 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19301

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 19302 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19359

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 19360 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19410

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 19411 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19467

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 19468 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19526

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 19527 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19584

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 19585 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19644

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 19645 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19703

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 19704 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19761

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 19762 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19817

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19873

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 19874 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19928

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 19929 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19987

Query: 1621  SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
               P        +T  P+P + L  T ++  S+S  W  P      ++  Y V    K + 
Sbjct: 19988 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20047

Query: 1673  GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
               +K       S+  VVSGL   ++Y   V+A      S P + ++  L  E + PP   
Sbjct: 20048 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 20105

Query: 1729  ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
                        R     +  I IS +              +    F  +    N    ++
Sbjct: 20106 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 20165

Query: 1769  RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
              ++  D   Y IT        K ++         + VV+D       P  +  +  T  S
Sbjct: 20166 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 20214

Query: 1829  LLVSWQPPR----ARITGYII 1845
             + + W+PP+    +++T YI+
Sbjct: 20215 VTLKWEPPKYDGGSQVTNYIL 20235



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 316/1532 (20%), Positives = 551/1532 (35%), Gaps = 236/1532 (15%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 22165 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22223

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 22224 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22279

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 22280 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22331

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 22332 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22389

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 22390 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22449

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 22450 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22503

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 22504 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22562

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 22563 AQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22620

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 22621 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22676

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 22677 DARLHGDLVTIRAGSDLV--------LDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22728

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 22729 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22787

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS---SCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+   +    S     L    EY   V  V
Sbjct: 22788 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22845

Query: 1251  KDDKESVPISDTIIPA-----VPPPTDL-RFTNIGPDTMRVTWAPPPSI---DLTNFLV- 1300
                   VP+    I A     +P P  +      G + + + W  P S    +++N+LV 
Sbjct: 22846 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22905

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 22906 KREKKSLRWTRVNKDYVVY-------DTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22958

Query: 1354  QKTGLDSPTGID-------FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                    P+            D T +S ++ W  P       I GY +    +      R
Sbjct: 22959 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 23018

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 23019 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 23077

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 23078 DDLKKTVTIRAGASL------RLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23130

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 23131 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23189

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 23190 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23248

Query: 1622  QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
             +P   +    V+ +P  P  L+   VT ++++  W  P      +LTGY +         
Sbjct: 23249 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23308

Query: 1674  PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
              MK + L P      V+ L    +Y        E  V   ++T+T+   Q   V+ T++ 
Sbjct: 23309 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 23368

Query: 1724  VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
              + P++     A    E  I I+ R        F    +  + +  ++   K    +   
Sbjct: 23369 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 23428

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
             T ++   +Y + L  +      +  VI           ++       S+ +SW+PP    
Sbjct: 23429 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 23488

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA-----LKNN 1889
              A ++GY+++      P    V      VT +T   T L  G EY   V A     + + 
Sbjct: 23489 GAPLSGYVVEQRDAHRPGWLPVSE---SVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23545

Query: 1890  QKSEPLIGRKKTGQEALSQT-----------TISWAPFQD-----TSEYIISCHPVGTDE 1933
              +SE +  R         +T           T++W P +D      + YI+    V  D 
Sbjct: 23546 LQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 23605

Query: 1934  EPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                  +VP T T    TGLT G  Y   V A+
Sbjct: 23606 WVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAI 23637



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
             T  +VT L  G  Y F+V  V+     +PL +     LD       PT+L+  + T  ++
Sbjct: 19568 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19627

Query: 1014  LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
              + W+ P +    +I+GY +     RR +     V   V+K P+ +L+  S         
Sbjct: 19628 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 19681

Query: 1061  EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
             EY V      G    ++ SP          P     P   +  +TTI I W        A
Sbjct: 19682 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 19741

Query: 1111  PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
             P  G+ +  + S   +    + S  G+   +SGLT G EYV+ ++ +      D  +   
Sbjct: 19742 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19801

Query: 1165  PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
             P + K      P  ++  E      V       +TV +     P++    + + P    +
Sbjct: 19802 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 19856

Query: 1218  GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
               +  +   + ++S T +N +     +Y +++  V     S+ +   ++    PPT++  
Sbjct: 19857 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 19914

Query: 1276  TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
              ++  ++  ++W  P +          +PVKN      E   +  +S ++N    +  +T
Sbjct: 19915 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 19967

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
             NL  G  Y   VS   E     P   ++   +      P  +  + I+ +S ++ W+ P 
Sbjct: 19968 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 20027

Query: 1383  ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
                 G RI H+      + +++ V  +    T   ++ L   +EY   + A N    S  
Sbjct: 20028 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20086

Query: 1438  -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
                  P+LI +Q    ++     P     V A      +  D P       ++T    G 
Sbjct: 20087 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 20143

Query: 1488  N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                    F    +    TI+ LK  V      Y +T    S  +   I+I     +D+P 
Sbjct: 20144 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 20199

Query: 1547  Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
                  + ++D+ + S+++KW P      S VT Y +     +    T+  +A   +T M 
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 20258

Query: 1599  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
             +  L    EY   + A+N  G S  +    VT     T P P    + T VT  S++  W
Sbjct: 20259 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 20318

Query: 1653  TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
               P       + GY + +  +      K   L   ++   V+ +     YE  VYA    
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 20378

Query: 1709  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
                +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V+   +P
Sbjct: 20379 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 20438

Query: 1761  ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
                 T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T ID+
Sbjct: 20439 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 20494



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)

Query: 730  EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
            +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 7126 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7184

Query: 786  YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
            Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 7185 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7244

Query: 836  APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
            + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 7245 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7304

Query: 896  QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
            +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 7305 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7364

Query: 949  EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
               + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 7365 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7423

Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
            T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 7424 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7483

Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
             + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 7484 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7543

Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
            G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 7544 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7602

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
              +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 7603 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7659

Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
               +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 7660 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7719

Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
              NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 7720 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7778

Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
            + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7838

Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 7839 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7898

Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
             P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 7899 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7946

Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 7947 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8002

Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 8003 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8062

Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
            M  + +   +E   SV A         +N  G +   +   V  +P P  D+K + +T +
Sbjct: 8063 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8122

Query: 1647 SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
            S    W PP     T     V  + + G    I +    +  S  V  L+   +Y   V 
Sbjct: 8123 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8182

Query: 1704 ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
            A+     ++   G    L+N            PP    V + T   +TI+W+        
Sbjct: 8183 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 8237

Query: 1750 TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
             I G+ ++ + A G+   +R  +    + +YT  GL+ G +Y+  +       +++ +R+
Sbjct: 8238 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 8296

Query: 1803 SPVVIDASTAIDAP 1816
            +P    A   IDAP
Sbjct: 8297 TPPT-KAVDPIDAP 8309



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 272/1303 (20%), Positives = 467/1303 (35%), Gaps = 174/1303 (13%)

Query: 773   TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  +  LL G +YI     VN Y + E  E   I +    T P  P    +  V   S+
Sbjct: 19568 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19627

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
              + WSRP++     I+GY I            +N  P     V  + L+ G +Y   +YA
Sbjct: 19628 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 19687

Query: 883   VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
                 + +  + +  ET+   R++    +PSP    + V+     +TI W  P     + +
Sbjct: 19688 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 19743

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
             TGY V+    +   +    +   R T   ++GL+ G  Y F+V +V+    S P  +   
Sbjct: 19744 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 19802

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
             Q   + +        +E   T++V+         G   T+ +  RG+P            
Sbjct: 19803 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 19854

Query: 1040  ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                R Y V  + S+  L     N   + +YT+++  +           V  T  P ++I 
Sbjct: 19855 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 19913

Query: 1093  PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
                 +VT+ + V++W        AP   + +  R +   +A   VT++    S  V+ L 
Sbjct: 19914 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 19970

Query: 1145  PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
              G  Y + +    +   G   +     K+    SPP  L + +     V +++W   E  
Sbjct: 19971 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 20029

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                 I  Y +        Q N ++  V A  +      L    EY   V+       S P
Sbjct: 20030 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20086

Query: 1259  ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
               + ++P +      PP  D++  N    T+ V       +D+         V    D  
Sbjct: 20087 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 20143

Query: 1313  ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
              L  +   N  +   NL    +  V+  +   +  +    G  K  ++         PTG
Sbjct: 20144 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 20203

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              +  SDIT  S T+ W  P+    + +T Y +    E  +    E     +R  + +  L
Sbjct: 20204 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 20262

Query: 1419  TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             T G EY   I A N        + + + +    T    P    V   T  S+ + W  P 
Sbjct: 20263 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 20322

Query: 1473  VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
                   V  Y +   +       +   +    +   ++ +  G+ Y   VYA    G   
Sbjct: 20323 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 20382

Query: 1529  ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
              S     +      + P  +++TD+  NS+S+ W        S +TGY V          
Sbjct: 20383 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 20442

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ----TAVTTIPAPT--- 1636
             TK       +T+  I GL    +Y   V+A+N  G  S P       T + +   P    
Sbjct: 20443 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20502

Query: 1637  DLKFTQV------TPTSLSAQWT-PPNVQLTGYRVRVTPKE-KTGPMKEINLAPDSSSVV 1688
              L++T+V      T   L A  +  P   +  Y+     KE +T  +  +    D +S++
Sbjct: 20503 PLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYK---DDKELQTNALVCVENTTDLASIL 20559

Query: 1689  VSGLMVATKYEVSVYALK--DTLTSRPAQGVVTTLENVSPPRRA-RVTDATETTITISWR 1745
             +     A +     Y LK  + + S  A   V  L+   PP         T   IT+ WR
Sbjct: 20560 IKD---ADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWR 20616

Query: 1746  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
                +     IT + V+    +       +   +    T T +  G +Y   +  +N    
Sbjct: 20617 PPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 20676

Query: 1802  SSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPG 1851
               P+  D+  A +A      P        T NS+ V W  P A     I+GY ++     
Sbjct: 20677 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 20736

Query: 1852  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTI 1911
             S     V +     T   +TGL   ++Y   V A+               GQ        
Sbjct: 20737 SLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVN------------AAGQ-------- 20776

Query: 1912  SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 1954
                PF + SE+  +  P+     P + R+  ++ S+   G ++
Sbjct: 20777 --GPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSK 20817



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12328 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12385

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12386 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12433

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12434 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12493

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12494 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12553

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12554 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12613

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12614 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12665

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12666 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12725

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12726 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12783

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 12784 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12841

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 12842 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12899

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 12900 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 12959

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 12960 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13004

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 13005 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 13062

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 13063 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 13122

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 13123 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13182

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 13183 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13237

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 13238 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13296

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 13297 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13353

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 13354 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13411

Query: 1630  TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
                P  P ++   +++  S    W PP +     +  Y V+    E+      +      
Sbjct: 13412 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 13470

Query: 1685  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
             +S  V+ L     Y   V+A  +     P +    V   +   P    +V   ++++ +I
Sbjct: 13471 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 13530

Query: 1743  SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
              W+         I G+ VD +    +   QR +K     Y+   L  G +Y   +   N+
Sbjct: 13531 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 13588

Query: 1799  NARSSP--VVIDASTAIDAP 1816
             N   +P  + + A   + AP
Sbjct: 13589 NGEGTPSEITVVARDDVVAP 13608



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 271/1284 (21%), Positives = 458/1284 (35%), Gaps = 188/1284 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 21048 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21107

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 21108 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21166

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 21167 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21221

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 21222 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21279

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 21280 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21339

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 21340 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21399

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 21400 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21459

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 21460 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21517

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 21518 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 21573 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21627

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 21628 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21684

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 21685 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21742

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 21743 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21802

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 21803 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21850

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++    P+ ++VTD    ++S++W        
Sbjct: 21851 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21910

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 21911 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21970

Query: 1627  T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
             T    AV  + AP    D  F Q       A     +++L   Y+ R TP    + P   
Sbjct: 21971 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 22025

Query: 1678  INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
             ++L  D  ++   S L V       A KY ++V   ++   S+     V  L+   PP  
Sbjct: 22026 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 22082

Query: 1730  ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
                 D T  + T+ W          I  + V+   A+ ++    + K   + + +  L  
Sbjct: 22083 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 22142

Query: 1786  GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
             G  Y   +  +N+         P  I A+     P  L  + T+ +S +++W  P     
Sbjct: 22143 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 22202

Query: 1838  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
             +RITGY+++  + GS     V          T+  L   TEY   V A  +   SEP   
Sbjct: 22203 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP--- 22257

Query: 1898  RKKTGQEALSQTTISWAPFQDTSE 1921
                  +EA S   I     + T++
Sbjct: 22258 -----REAFSSVIIKEPQIEPTAD 22276



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)

Query: 710  TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
            TV+   TP  P+    E   +I  +S +  W    D      + Y L ++     + +++
Sbjct: 8423 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 8479

Query: 767  DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
             + ST      ++  L+ G++Y+  V   +  G         +++      PDAP  P V
Sbjct: 8480 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8539

Query: 820  DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
            + V   S++V+W+ P+   +PI GY   +    E +ST  +    +    L     G+  
Sbjct: 8540 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 8596

Query: 877  NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
             +T ++ V     + P      +      D +  P P   +  + +   + + W PP   
Sbjct: 8597 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 8656

Query: 932  --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
                + GY VD  ++  N      +++  + + T  E+     G  Y  +V AV+   E 
Sbjct: 8657 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 8713

Query: 987  KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
             P   Q  T          +LD             T+ +             WT    ++
Sbjct: 8714 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 8773

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
               R+ +           NVG     + K  LR  +    Y ++     G++ +     V
Sbjct: 8774 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 8821

Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
            F    P   + P  T       ++ W+       +   GF +  + ++     + + ++ 
Sbjct: 8822 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 8879

Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
                ++GL  G EY +  +V+   +    P V       V PL PPT+     + E    
Sbjct: 8880 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 8937

Query: 1188 TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
            T  +T+ W+   +     I GY I     +      + + +    +S   +NL     Y 
Sbjct: 8938 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 8994

Query: 1245 VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
              V  V +  ES   +P++  I     PPT     ++  DT++V    P  I  D+T   
Sbjct: 8995 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 9054

Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
            +        E V E    P+D   +    +  +E    +S   +V E   +  +    + 
Sbjct: 9055 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 9111

Query: 1357 GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
            G                P  +  +DI A S  + W AP     G  I H+   +  + R 
Sbjct: 9112 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 9170

Query: 1402 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
            + +    +  ++     +  L P  +Y   + A+N    S      +  + D       P
Sbjct: 9171 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 9230

Query: 1452 RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
               +V+A T  S+L+SW  P       +  Y +   E G         +P+ +  + G +
Sbjct: 9231 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 9290

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
                +  L  GV Y     A+   G  P S  S P ++ +       PS  +V D   +S
Sbjct: 9291 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 9348

Query: 1558 ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
            IS+ W P +    SP+ GY V    +   G T  K    PD+   T E + P ++    Y
Sbjct: 9349 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 9405

Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
               V A N +GES+P   T    IPA TD++        + AQ     V   G ++R+  
Sbjct: 9406 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 9460

Query: 1667 ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
                  TPK   E  G  K              ++  A +SS +++     +   + S+ 
Sbjct: 9461 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 9520

Query: 1704 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
            A K+    + A   V  ++   PP+  +V+D T  +  +SW+   +     I G+ ++  
Sbjct: 9521 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 9579

Query: 1760 PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
              +G+   +  + PD  S T  +  L     Y   +   N      PV  I  +TA D  
Sbjct: 9580 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 9637

Query: 1816 -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
                 P  L+    T N++ +SW+PP+    + +T YI++   ++  G+         + 
Sbjct: 9638 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 9697

Query: 1864 GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
             V E   T+  L  G EY   V A+     S+P
Sbjct: 9698 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9730



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1521 (20%), Positives = 534/1521 (35%), Gaps = 198/1521 (13%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+      P++       P ++ + +     NS  + W  P+    S I +YI+  +
Sbjct: 16741 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 16798

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K+S  +W E      L +  I  L  G  Y  +++++ + G  +         S + P+
Sbjct: 16799 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 16849

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E        + S  V +       +S      T++  +    L +        
Sbjct: 16850 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 16908

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
              L  T  S+       G +Y + V  +   G+++  +       PD P  P   D V   
Sbjct: 16909 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 16966

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
             SI + W+ P       IT Y +    +       ++      ++ ++ L+ G +Y   I+
Sbjct: 16967 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 17026

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
             A  EN+      ++ +          P P    F   ++   + I W  P     S V G
Sbjct: 17027 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 17084

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
             Y ++    N          I  +T  +   L  G+ Y F+V+A   V  G+ SK      
Sbjct: 17085 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 17144

Query: 994   TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
                  D P   + +    + + ++WT P     + ITGY +       G+  + +    +
Sbjct: 17145 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17204

Query: 1049  -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
              +++ +  L     Y   ++A    G    P  +TG  T       P  S+ P   +  +
Sbjct: 17205 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 17261

Query: 1101  TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             T +V           +   P P I +  G +   +      + T     ++V        
Sbjct: 17262 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17321

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
               Y ++       +  P+  KV+    PP          +   +++W    +    DI+ 
Sbjct: 17322 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 17381

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
             Y +    T+      +   V  +    T   L  G EY      V+ Y V +  ES P+ 
Sbjct: 17382 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17439

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
               +  ++P   PP  L  TNI  D+M V W  P S   +  +      ++   +  +  +
Sbjct: 17440 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 17497

Query: 1318  P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
                 +D  + +T L    EY   VS  +     E +P     K          PT     
Sbjct: 17498 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 17557

Query: 1368  DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
             D T NS T+ W  P     + I GY +    E       E ++   +  + +T      L
Sbjct: 17558 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 17613

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
             T   EY + + ALN      + +G+ ++V    +  + + A P   L S     + VR  
Sbjct: 17614 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 17667

Query: 1477  -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
                RI     G  +P   ++    + T  +  ++ GV+YT              Y +   
Sbjct: 17668 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 17726

Query: 1525  GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
               S + S  +++        P  + V +V+ +S  + W P      + V  Y +      
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 17786

Query: 1581  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
                     ++   +T   +E L     Y   V A+N  G   P+     V+ A    P P
Sbjct: 17787 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 17844

Query: 1636  TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
               +  T V+ TS S  W  P      ++ GY V + PK  EK   + E  +     + VV
Sbjct: 17845 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 17900

Query: 1690  SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
             +GL    +Y+  V A  +   S P   GV      +T   ++  P       A E     
Sbjct: 17901 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 17960

Query: 1738  ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
                       ISW    E +   T   V+    +    I+   K D   YT+T       
Sbjct: 17961 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 18019

Query: 1789  YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
                   T  +N   S +V++       P  +RF   + + +++SW+PP      +I+ YI
Sbjct: 18020 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 18069

Query: 1845  IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR------ 1898
             ++     +    +V       T   IT L+ GTEY   + A     KS PL  +      
Sbjct: 18070 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQY 18128

Query: 1899  --KKTGQE--------ALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQF----RVPGT 1943
               K+ G          +  Q  + W  P  D    II  H    ++  + +    + P  
Sbjct: 18129 PFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 18188

Query: 1944  STSATLTGLTRGATYNIIVEA 1964
              T    TGL  G  Y   V A
Sbjct: 18189 DTKFKTTGLDEGLEYEFKVSA 18209



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20196 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20255

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20256 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20313

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20314 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20372

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20373 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20431

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20432 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20488

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20489 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20548

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20549 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20608

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20609 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20665

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 20666 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20725

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 20726 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20785

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 20786 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20841

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 20842 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20901

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 20902 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20957

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 20958 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21012

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 21013 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21070

Query: 1616  NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
             N  G  +P   T       +PAP  DL     T TS+   WT P+      +T Y V   
Sbjct: 21071 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21130

Query: 1668  PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
              K E+T     I+    +  + VS L   +  E  V+A  +   S P   G +T  E + 
Sbjct: 21131 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 21187

Query: 1726  PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
              P          +  V       + + ++ K +    +  D +P      ++  +T    
Sbjct: 21188 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 21247

Query: 1775  VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
               S      + G  Y + L    DNA     V      +  PS     +RF     +S++
Sbjct: 21248 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 21303

Query: 1831  VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
             +SW  P       IT Y I+  +      ++V       T   +  L    EY   V A 
Sbjct: 21304 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 21362

Query: 1887  KNNQKSEPLI 1896
                  S+PL+
Sbjct: 21363 NRYGVSQPLV 21372



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1485 (20%), Positives = 517/1485 (34%), Gaps = 213/1485 (14%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
             S+ + T +S ++SW            EY +  +G   Q       + +  I ++   ++ 
Sbjct: 21098 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 21156

Query: 787   IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
              V  +++    E+ L   ++    T  +    P VD  D     + VR          Y+
Sbjct: 21157 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 21216

Query: 843   IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
                 PS+      L L E        T N +TLS      ++      + +N      V 
Sbjct: 21217 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 21276

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
             I   T G P     P    ++F E+    V + W  PE      +T Y ++    +    
Sbjct: 21277 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21332

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
                   ++R TF +V  L     Y F+V A +    S+PL      A+   ++  P    
Sbjct: 21333 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 21391

Query: 1005  FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
              + N T   + + W  P     +++TG+ +          ++ N  P S  +Y    L  
Sbjct: 21392 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 21451

Query: 1059  ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
               +Y   + A       SP     FT        P  P   +VT  TI + W P  R G 
Sbjct: 21452 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 21511

Query: 1116  K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                    +   QG E  R V  +   +      V+GL+PG  Y + I            I
Sbjct: 21512 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 21557

Query: 1167  VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
                 V  +SPP+                +E  P+   G++  S E      +   R    
Sbjct: 21558 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21617

Query: 1212  PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
              T  + G  +E+ ++    D    T   +      +  VYTV+    S        V + 
Sbjct: 21618 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
             DT    V P   +RFTNI  + M + W  P +     +T++++             ED  
Sbjct: 21678 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 21734

Query: 1313  ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
             E   + S  A+ L N   G EY   VS+V +     PL         Q T  D+P   + 
Sbjct: 21735 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21788

Query: 1367  SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
             S+IT NS T+ W  P     + I  Y +    +  +   +   + P S     +T LT G
Sbjct: 21789 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21848

Query: 1422  TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
              EY   ++A N     P      LI  +  V+    P  ++V   + T++ + W  P   
Sbjct: 21849 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21908

Query: 1475  VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
                  I Y      + + ++    +    K+  T++ L+ G +Y   V A+   G+GDS 
Sbjct: 21909 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 21968

Query: 1528  --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
                 + K +      E+D  +  + T V     S++ ++      T   V + P +    
Sbjct: 21969 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 22028

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
                       + +T+E          ++  +N SG         V   P P   + F  V
Sbjct: 22029 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 22088

Query: 1644  TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
             T  S +  W  P +   G R+     EK    +     I+         V+ L     Y 
Sbjct: 22089 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22147

Query: 1700  VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
               V A+ +     P +    +   E  +PPRR  V D ++++  ++W          ITG
Sbjct: 22148 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 22207

Query: 1754  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
             + ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S  I
Sbjct: 22208 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22266

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT---- 1866
               P         P + L         IT  +I   K GSP    VP   RP P VT    
Sbjct: 22267 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVTWKLE 22312

Query: 1867  --------EATITGLEPGTEYTI----------YVIALKNNQ-------------KSEPL 1895
                       +IT  +  T  T+          Y + L+N               +  P+
Sbjct: 22313 EMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPV 22372

Query: 1896  IGRKKTGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 1950
              G  +    +     +SW   +D      + YI+     GT    L        T   +T
Sbjct: 22373 TGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL-VNSSVKRTQIKVT 22431

Query: 1951  GLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE 2010
              LT+   Y+  V +   + R  V + + +           P+  +  + Y VS  A+   
Sbjct: 22432 HLTKYMEYSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22488

Query: 2011  WERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGV-----NYKI 2050
             WE     G     + +G+       ++  W  +N V     NYK+
Sbjct: 22489 WEEPYHDGGS---KIIGYWVEKKERNTILWVKENKVPCLECNYKV 22530



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 272/1331 (20%), Positives = 495/1331 (37%), Gaps = 207/1331 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8843  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8900

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8901  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8947

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 8948  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9007

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 9008  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9063

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 9064  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 9124  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9180

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9181  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9240

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9241  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9296

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9297  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9356

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9357  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9412

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9413  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9472

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 9473  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9531

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 9532  CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9590

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 9591  PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9650

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 9651  ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9710

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 9711  EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9770

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 9771  VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9830

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 9831  G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9887

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T     +
Sbjct: 9888  N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943

Query: 1632  IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
             +P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N  P  +
Sbjct: 9944  VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 10001

Query: 1686  -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
                  S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP     +V
Sbjct: 10002 MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 10057

Query: 1733  TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
             TD T+++  + W    +     +TG+ V+     G+   ++    +VR     +TGL+ G
Sbjct: 10058 TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 10116

Query: 1787  TDYKIYLYTLN 1797
               YK  +  +N
Sbjct: 10117 AFYKFRVRAVN 10127



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)

Query: 609  SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
            S P E+   E P+ P S P+  +        K+I + W+P  KN     +G   E    G
Sbjct: 7898 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 7955

Query: 662  -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
                  +NS  IK LK     GVV + + +    ++   G  E +       +   P   
Sbjct: 7956 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 8014

Query: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
             T+  ET     +     S+  +   +  V  VS        +    L+ + D       
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 8067

Query: 769  PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               +  + +P  +     I  +   ++ G  +  ++      P    D     +  +S  
Sbjct: 8068 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8125

Query: 829  VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
            + W  P+     PI  Y +    +   +   +   E   S T+ DL P  +Y   + AV 
Sbjct: 8126 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 8185

Query: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
            +      + ++              P D++    T   +TI W PP     S + GY ++
Sbjct: 8186 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 8245

Query: 941  VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
             I     GE   +      +PI   T     GL  G  Y F+V A +    S+P  A   
Sbjct: 8246 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 8299

Query: 995  TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
            TK    +DAP     T+L+ V   D   L           + W      I    +     
Sbjct: 8300 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 8358

Query: 1032 GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
             L RR     Q  +  V P   +  + N +                  Y + +    G  
Sbjct: 8359 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 8418

Query: 1074 ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
            ++P    V  T  PG  I     ++ +T+++  W P    G    +  +   E   +   
Sbjct: 8419 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 8474

Query: 1134 DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
            DS  IVV+            L  G EY++ ++   +      P V+K +    P  PP  
Sbjct: 8475 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 8533

Query: 1179 -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
             +  +  +  +  + V W   +     I GY +     N    + + + +  +      D
Sbjct: 8534 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 8592

Query: 1236 NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
             L  GL Y   V         +  P SD      P  PP P   R T+    T+ + W P
Sbjct: 8593 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8652

Query: 1290 PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
            P      ++  + V    V   E               +  +  G +Y + VS+V    E
Sbjct: 8653 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8712

Query: 1347 STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
              P   +  T  +   P  ++          +        + G  +R  P   +GRP   
Sbjct: 8713 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 8763

Query: 1405 RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
            +V         ++ + + N+   +E ++            I A N           +  V
Sbjct: 8764 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 8821

Query: 1448 SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
             DVP    DL+ V       L++W  P            E  G S +  F +        
Sbjct: 8822 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 8869

Query: 1500 ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
                     +S   I+GL  G +Y   V A    G  P    P+ I     +D       
Sbjct: 8870 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 8925

Query: 1545 PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            P ++  T+   ++I++ W        SP+ GY +     + P   +        T   +E
Sbjct: 8926 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 8985

Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
             L     Y   V A N  GES+P       ++P    ++  +V PT    LS +     V
Sbjct: 8986 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 9038

Query: 1658 QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
            +  G  V + P + TG PM +I  + + + +   +  +  TK EVS             V
Sbjct: 9039 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096

Query: 1703 YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
               K T T   +  + +   NV        SPPR   VTD    +  ++W    +     
Sbjct: 9097 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 9156

Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
            IT + +D   A+ +      +      + Y I  L P   Y+  +     Y ++D  +S 
Sbjct: 9157 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 9216

Query: 1804 PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
             VVI D       P   + LA T  S+LVSW PP     + ITGY ++  + GSP    V
Sbjct: 9217 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 9276

Query: 1859 PRPRPGVTEATITGLE 1874
               R  +T+  + G+E
Sbjct: 9277 --SRAPITKVGLKGVE 9290



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 171/752 (22%), Positives = 283/752 (37%), Gaps = 116/752 (15%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 9705  TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9764

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 9765  VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9818

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 9819  TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9876

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 9877  ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9929

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 9930  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9989

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 9990  RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 10046

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 10047 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10106

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
             ++ + GL+    Y   V A N +G  +P   T V       ++K   V+P   L A    
Sbjct: 10107 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 10160

Query: 1655  PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
               V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   V
Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10220

Query: 1703  YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
             Y+L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + 
Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10280

Query: 1756  VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
             ++   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+
Sbjct: 10281 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10338

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
              +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V    
Sbjct: 10339 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10398

Query: 1863  PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 + T+ GL+ G  Y   V A+    + +P
Sbjct: 10399 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10430



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 258/1144 (22%), Positives = 397/1144 (34%), Gaps = 207/1144 (18%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
             P P ++L+   VT    TI W  P     S +T +   ++    P + G  +  S  T  
Sbjct: 11630 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNF---IVEYRKPNQKGWSIVASDVTKR 11686

Query: 963   EV-TGLSPGVTYYFKVFA-----VSHGRESKP--LTAQQTTKLDAPTNLQFVNETDSTVL 1014
              +   L     YYF+V A     V    E+K   L      +   P NL   ++  + V 
Sbjct: 11687 LIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVY 11746

Query: 1015  VRWTPPRAQITGYRLTVGLTRR------------GQPRQ--YNVGPSVS------KYPLR 1054
             ++W  P        L+  + RR            G  ++  Y V   V       +   +
Sbjct: 11747 LKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTK 11806

Query: 1055  NLQPASEYT-VSLVAIKGNQESP----KATGVFTT-------LQPGSSIPPY-NTEVTET 1101
             N    S++     V +K + + P    K +GV T        L+ G    P+     T+ 
Sbjct: 11807 NEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD 11866

Query: 1102  TIVITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVY--TIQVLRD 1158
                   T +PR+  K+  R  S      +   SD G  VV+       +V   T+ VL  
Sbjct: 11867 KDATDLTRSPRV--KIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL-- 11922

Query: 1159  GQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVS---WERSTTPDI--TGYRIT--- 1209
               ++  P+ N K+V   S    +  +   D G   +     E+  T  +  + Y  T   
Sbjct: 11923 --DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLT 11980

Query: 1210  --TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
               TT T   +GN     V A+    T     P  E    +   K DK          P  
Sbjct: 11981 PGTTVTRLIEGNEYIFRVRAENKIGT----GPPTESKPVIAKTKYDK----------PGR 12026

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVV 1324
             P P ++  T +  + M V W PP      +    +   K +     + ++ S   +  + 
Sbjct: 12027 PDPPEV--TKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMK 12084

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDS------PTGIDFSDITANSFTVH 1377
             + NLLP  EY   V +  E     P L  R     D       PT     D T +S T+ 
Sbjct: 12085 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 12144

Query: 1378  WIAP----RATITGYRIRHHPEHFSGRPRED------RVPHSRNSITLTNLTPGTEYVVS 1427
             W  P     A I GY +   P+     P E            R   T+T+L    EY   
Sbjct: 12145 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 12204

Query: 1428  IVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
             + A N      + IG+ + + +  +  E++      L  S     V VR           
Sbjct: 12205 VCAQN-----QVGIGRPAELKEAIKPKEILEPPEIDLDASM-RKLVIVR----------A 12248

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTIT-------------VYAVTGRGDS------- 1527
               P++ F +   +    ++  K G+D  +              V   + R DS       
Sbjct: 12249 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 12308

Query: 1528  --PASSKPISINYRTEIDKP---SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
               PA  K + +N R  +D P   S ++V+DV   S  V W P      S VT Y V    
Sbjct: 12309 VNPAGEKAVFVNVRV-LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKRE 12367

Query: 1579  KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTT 1631
              +      T T    +T   +  L P  EY   V A N  G   P       L    ++ 
Sbjct: 12368 ADRK-TWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE 12426

Query: 1632  IPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
                P  L+ T++T  S +  W PP        +  +T YR    P ++     E ++  D
Sbjct: 12427 PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKD 12483

Query: 1684  SSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----- 1736
              S +VV+GL    KY+  V A      S P  A+GV    E + PP+       T     
Sbjct: 12484 LS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGK 12542

Query: 1737  ----------ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGL 1783
                       +   T  W+  + E +T   +    A+  +   I+   + D   Y++T  
Sbjct: 12543 KLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAE 12602

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----AR 1839
                           D  +   VV+DA      P ++  +     SL  SW  P     + 
Sbjct: 12603 NSSG---------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSN 12651

Query: 1840  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1899
             IT YI++ +   S    V        T   +  L PG EY   V A      SEPL   K
Sbjct: 12652 ITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPK 12710

Query: 1900  KTGQ 1903
                Q
Sbjct: 12711 MVAQ 12714



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 117/534 (21%), Positives = 206/534 (38%), Gaps = 63/534 (11%)

Query: 1414 TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
            T+T L  G  EY+  + A N          ++P+    +  V   P ++ +       + 
Sbjct: 6777 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 6836

Query: 1466 ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
            ++W+ P       +  Y I   +          TV     +AT++ +  G +Y+  V A 
Sbjct: 6837 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 6896

Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
               G    S+    +     I++PS    +  +D   +S+ +KW P      SP+ GY +
Sbjct: 6897 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6956

Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
                +      +       +    + GL+   +Y+  V A+N +G S P      + I  
Sbjct: 6957 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 7010

Query: 1635 PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
            P       V PT  LSA     +   PN     V  TGY R   T        +TG   +
Sbjct: 7011 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7070

Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
            +      + +V+S    + + +  +Y LK     +   G   V  +   S P+  +  D 
Sbjct: 7071 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 7127

Query: 1736 TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
            T+ ++ ++W    +     +TG+ V+    + +T  +         +T+  L  G +Y  
Sbjct: 7128 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 7187

Query: 1792 YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
             +   N      P  +D        +T  D P N+++   T NS+ ++W PP+    +RI
Sbjct: 7188 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 7247

Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             GYI++    GS        P    T+  +TGLE G  Y   V AL     S+P
Sbjct: 7248 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7300



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)

Query: 806  SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
            S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 6814 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6873

Query: 861  TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
               S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 6874 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6928

Query: 916  VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
             + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 6929 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6988

Query: 972  TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
             Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 6989 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7048

Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
             PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 7049 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7104

Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
            +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 7105 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7159

Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
            +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 7160 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7219

Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
             N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 7220 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7277

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
              L  G  Y   V  +     S P   T  I AV                          
Sbjct: 7278 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7336

Query: 1272 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
            +L  T  G    ++TW     I   +  +    V  +  V  +    SD          G
Sbjct: 7337 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 7387

Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
            T  + +V+          +    K G   P   D +D+T  S  + W  PR    + IT 
Sbjct: 7388 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7445

Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
            Y +         R  +  V H  +S         T L P  EY+  + A N        +
Sbjct: 7446 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 7498

Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
             SP+    Q      P  LE    T  ++ ++W  P       +  Y +   +   +  V
Sbjct: 7499 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7558

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
            +   +P   +T  + GL     Y   V A  + G G    S++PI I  +  ID P    
Sbjct: 7559 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 7616

Query: 1547 QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
            +  V DV   S+ + W        + +  Y V    K G         G   T+  + GL
Sbjct: 7617 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 7675

Query: 1603 QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
                EY   V A N +GES+P       L +  +     P  L+   +T  +   +WT P
Sbjct: 7676 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 7735

Query: 1656 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
                   +T Y V      + G  + ++     +   V+ L      E S+Y  +    +
Sbjct: 7736 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 7789

Query: 1712 RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
               Q   T +E+            PP    V D T+  + + W          I  + ++
Sbjct: 7790 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 7849

Query: 1758 AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
                 G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P        + D
Sbjct: 7850 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 7908

Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
             ++    P +L         + ++W+PP     + I GY ++    G+     V  RP  
Sbjct: 7909 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7968

Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             +      G+ P  EY + V A+     SEP
Sbjct: 7969 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7999



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 265/1308 (20%), Positives = 462/1308 (35%), Gaps = 209/1308 (15%)

Query: 814   PPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
             P D T D     S+ + W  P     + IT Y +    +   S +         +  ++ 
Sbjct: 14504 PTDITKD-----SVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTG 14558

Query: 870   LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWT 928
             L  G +Y   + A  E     P     ETT   ++   PSP D L  +++T   V++ W 
Sbjct: 14559 LSEGCEYFFRVMAENEYGIGEPT----ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWP 14614

Query: 929   PPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHG 983
              P+    S +TGY   VI     G +    +   +     V  L+ G  Y F+V AV+  
Sbjct: 14615 KPKHDGGSKITGY---VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSA 14671

Query: 984   -----RESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
                  RES+P+  ++ T L     L         V+ +         G  + V +   G+
Sbjct: 14672 GRSAPRESRPVIVKEQTMLP---ELDLRGIYQKLVIAK--------AGDNIKVEIPVLGR 14720

Query: 1039  PRQ---YNVGPSVSKYPLR-NLQPASEYTVSLV--AIKGNQESPKAT--------GVFTT 1084
             P+    +  G  + K   R N +  +  T+  +   ++ +      T        G   T
Sbjct: 14721 PKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVIT 14780

Query: 1085  LQ----PGSSIPPYN-TEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSG--- 1136
             +Q    PG    P    EV+   +  +W P    G   GV  S      R+  S +    
Sbjct: 14781 IQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDG---GVPISNYVVEMRQTDSTTWVEL 14837

Query: 1137  -------SIVVSGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEA 1184
                    +   + LT G+EY + ++      +  G      + N       PP    + A
Sbjct: 14838 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14897

Query: 1185  NPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGL 1241
                   +T+SW    +     I GY +     NG    ++ + +    +      L+ G+
Sbjct: 14898 VTKDS-MTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKAL-VPGNIFKSSGLTDGI 14955

Query: 1242  EYNVSVYTV------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---S 1292
              Y   V         K  K S P+    +  + PP      NI   T+ + WA P     
Sbjct: 14956 AYEFRVIAENMAGKSKPSKPSEPM--LALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGG 15013

Query: 1293  IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
               +T+++V    + N   +     +  +N   ++ L     Y   V +       +P   
Sbjct: 15014 FKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSE 15073

Query: 1353  RQ-----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY 1388
                    +  +++P     + F D        +F            T+ W      + G 
Sbjct: 15074 PSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGT 15133

Query: 1389  -RIRHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIG 1442
              ++      FS     +D       + TLT   PG   +++ ++  L+  G  E PL + 
Sbjct: 15134 AKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVT 15193

Query: 1443  QQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPG 1498
             +                T    ++SW  P       + +Y +   ET   +    +T   
Sbjct: 15194 E---------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVA 15234

Query: 1499  SKSTAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDV 1553
             S+   T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +
Sbjct: 15235 SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTI 15294

Query: 1554  QDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
               +S+ V W        S +  Y V    K G    K            + GL    EY 
Sbjct: 15295 TKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYE 15354

Query: 1610  VSVYAQNPSGESQPLVQT----AVTTI---PAPTDLKFTQVTPTSLSAQWTPP----NVQ 1658
               + A+N +G S P   +    A  T+     P + +    + +S+S  W  P      +
Sbjct: 15355 FRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSE 15414

Query: 1659  LTGYRVRVT-PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--Q 1715
             +TGY V +  P+E    +        ++S  ++GL    +Y++ +YA+       PA   
Sbjct: 15415 ITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVP 15474

Query: 1716  GVVTTLENVSPPR-------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
             G     + + PP        R  VT     T+ +    K       +V     +G++  +
Sbjct: 15475 GTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAP--EVKWARDHGESLDK 15532

Query: 1769  RTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLA 1823
              +I+    SYT  I G     D   Y+ T+ +++ S    ++    +D P    +L+   
Sbjct: 15533 ASIE-STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV-LDTPGPPQDLKVKE 15590

Query: 1824  TTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1879
              T  S+ ++W PP     ++I  YI++  +        V       T   +  L+ G  Y
Sbjct: 15591 VTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVAT-NCHKTSWKVDQLQEGCSY 15649

Query: 1880  TIYVIALKN-------------NQKSEPLIGRKKTGQEAL-SQTTISWA-PFQDTSE--- 1921
                V+A                     PL   K T  +   +  ++SW  P  D      
Sbjct: 15650 YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRIL 15709

Query: 1922  -YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 1968
              YI+     G+D+      V    T AT+TGL +G  Y+  V A  ++
Sbjct: 15710 GYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEK 15755



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 15978 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16037

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 16038 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16082

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 16083 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16142

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 16143 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16200

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 16201 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16254

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 16255 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16311

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 16312 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16371

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 16372 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16430

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 16431 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16490

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 16491 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16550

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 16551 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16607

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 16608 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16662

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 16663 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16721

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 16722 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16781

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 16782 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16839

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 16840 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16897

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 16898 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16949

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 16950 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17009

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
                   + +  L+   EY   ++A+N  G     ES P+V       P P    F T ++
Sbjct: 17010 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17063

Query: 1645  PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
               S+  QW  P       + GY +    +      K        +      L    +YE 
Sbjct: 17064 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17123

Query: 1701  SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
              VYA       + ++        +   PP            IT+ W          ITG+
Sbjct: 17124 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17183

Query: 1755  QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
              V+        P  R +K    +     +T++GL     Y+  +   N
Sbjct: 17184 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17227



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 21403 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21462

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 21463 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21507

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 21508 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21567

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 21568 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21622

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 21623 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21681

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 21682 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21737

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 21738 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21796

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 21797 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21855

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 21856 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21914

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 21915 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21973

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 21974 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22033

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 22034 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22092

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 22093 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22151

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 22152 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22211

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 22212 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22268

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 22269 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22324

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 22325 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22376

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 22377 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
              +EY   V ++N  G S+PL    +      +P  APT  +   V+  ++S +W  P   
Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22495

Query: 1656  -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
                ++ GY V    +     +KE  +     +  V+GL+   +Y+   YAL     S+ +
Sbjct: 22496 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22555

Query: 1715  QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
             +    +     V  P R  VTD T +T+++ W          + G+ ++  P +      
Sbjct: 22556 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 22615

Query: 1764  QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
                   TI  D   +T+T L  G  Y+  +   N
Sbjct: 22616 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 22648



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)

Query: 1412  SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
             S  +T L  G EY   I+A+N        E  P++      V D P+  EV   T  S++
Sbjct: 16323 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 16382

Query: 1466  ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             + W+ PA      +  Y +   +  G    +       +    ++GL    DY   V A 
Sbjct: 16383 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 16442

Query: 1522  TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
                G    SP S+   + +   +   P+  +V D+  +S+ + W          + GY V
Sbjct: 16443 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 16502

Query: 1575  TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
                  + G     T   G ++T + +E L    EY   + A N +G  +        +V+
Sbjct: 16503 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 16562

Query: 1627  TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
               +       DL+  ++                   + R TP+ K     G +++  +  
Sbjct: 16563 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 16618

Query: 1683  DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
              +SS     L    +Y+   Y L  +++  ++ A   V  L+  SPP   +VT+ T+ ++
Sbjct: 16619 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16678

Query: 1741  TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
             +I+W          I  + V+   A  ++           S+ I  LQ G  Y   +   
Sbjct: 16679 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16738

Query: 1797  NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
             N+     P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +
Sbjct: 16739 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16798

Query: 1849  KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                S       R +    +A IT L  G EY   V+A+    +S+P
Sbjct: 16799 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 16842



 Score = 78.6 bits (192), Expect = 6e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19696 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19755

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19756 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19807

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19808 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19859

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19860 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19917

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19918 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19977

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 19978 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20034

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 20035 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20088

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 20089 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20139

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20140 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20199

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20259

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20260 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20318

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20374

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 20375 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20419



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 278/1381 (20%), Positives = 487/1381 (35%), Gaps = 191/1381 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 10899 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10955

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 10956 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11014

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 11015 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11074

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 11075 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11132

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 11133 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11187

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 11188 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11245

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 11246 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11305

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 11306 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11365

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 11366 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11425

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 11426 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11484

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 11485 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11544

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 11545 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11602

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 11603 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11653

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 11654 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11711

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 11712 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11771

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 11772 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11829

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 11830 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11879

Query: 1599  IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
             I+    + ++ ++           V A N +G         V   P P  +LK   V+  
Sbjct: 11880 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 11939

Query: 1647  SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
               +  W PP     G  ++    EK    K +  +  S++V+  G  V    E + Y  +
Sbjct: 11940 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 11997

Query: 1707  DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
                 ++   G  T  + V           P    VT  ++  +T+ W        ++ITG
Sbjct: 11998 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 12057

Query: 1754  FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
             + ++    +     P+ ++  P+ R   +  L P  +Y+  +   N+      +  S PV
Sbjct: 12058 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 12116

Query: 1806  VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
             V  D       P+N R + TT +S+ + W  P     A I GY+++       + P E  
Sbjct: 12117 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12176

Query: 1859  PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWA 1914
              R          E T+T L+   EY   V A     +++  IGR    +EA+    I   
Sbjct: 12177 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA-----QNQVGIGRPAELKEAIKPKEILEP 12231

Query: 1915  P 1915
             P
Sbjct: 12232 P 12232



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 210/1000 (21%), Positives = 366/1000 (36%), Gaps = 157/1000 (15%)

Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
            P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 6720 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6779

Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
            GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 6780 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6837

Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
            +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 6838 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6896

Query: 1251 KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
                   P + T    V        PP +L  ++    ++++ W PP     S  L   +
Sbjct: 6897 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6956

Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
             R    K+      + + P +    +T L  G +Y+  VS+  +   S P         D
Sbjct: 6957 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7015

Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
                    D++A    +  I P           +P   +     D+V  + + + +  L+
Sbjct: 7016 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 7075

Query: 1420 PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
               E V+S    + +    L L  +  T+S             P++L+    T  S+ ++
Sbjct: 7076 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 7135

Query: 1468 WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
            W+ P            +  G SP+  + V   + +                T+  L  G 
Sbjct: 7136 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 7183

Query: 1513 DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
            +Y   V A    G G+     +P++++    + D P  ++  D   NSI + W P     
Sbjct: 7184 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 7243

Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
             S + GY V   P+   G  K    G    +T+M + GL+    Y   V A N  G S+P
Sbjct: 7244 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7300

Query: 1624 LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
               T    AV T  AP           L     T   L A  T  P  ++T  +  +  K
Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7360

Query: 1670 EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
            +     K I +   P  S+V +   + + + +   Y ++       A  VV    L+   
Sbjct: 7361 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 7413

Query: 1726 PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
            PP    +TD T  +  ++W    +     IT + V+    + +    +  T+K    ++ 
Sbjct: 7414 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 7471

Query: 1780 ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
             T L P  +Y        +Y + +  ++SP  I A    D    P+ L     T +++ +
Sbjct: 7472 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 7529

Query: 1832 SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
            +W  P     + ITGY ++   P +       +     T   + GL    +Y   V+A  
Sbjct: 7530 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 7589

Query: 1887 -----KNNQKSEPLI-----------GRKKTGQEALSQTTISWA-PFQD----TSEYIIS 1925
                 K ++ +EP++           G+        +   ++W  P  D       Y+I 
Sbjct: 7590 LAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIE 7649

Query: 1926 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                GTDE  ++      +T   L GL  G  Y+  V A+
Sbjct: 7650 MLKTGTDEW-VRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7688



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 316/1566 (20%), Positives = 536/1566 (34%), Gaps = 237/1566 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
             P  V +T+T     S  ++W+ P       I  YI+    K  +G W +      + + Y
Sbjct: 21885 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 21941

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
             T+  L+ G  Y+ ++ +I   G  +         S     T   V   T P   + A  +
Sbjct: 21942 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 21992

Query: 727   SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
                 + A + +  +++     + T    + +  LS   D     D  ST T  N      
Sbjct: 21993 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 22051

Query: 783   GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
             G KY + V   S  G +S+  +      P  P   T   V   S  + W  P     A I
Sbjct: 22052 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 22108

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
               Y +    +   S   ++   T     ++DL  GV Y   + AV E     P  + +  
Sbjct: 22109 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22168

Query: 899   TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
               T +      PR L  V+ +     + W  P+    S +TGY +++        +   H
Sbjct: 22169 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 22225

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
              ++L  +     E T       Y F+V A +    S+P  A  +  +  P          
Sbjct: 22226 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 22270

Query: 1011  STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
                      P A +TG    +   + G P   +V       P V+ + L  ++      V
Sbjct: 22271 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 22322

Query: 1065  SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
             S+   K       ++S +      F TL+  + +  ++      T+V+   P P  G   
Sbjct: 22323 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 22377

Query: 1115  ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
                          G  P  GG    E+T+      +SG+              I V+ LT
Sbjct: 22378 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22434

Query: 1145  PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
               +EY + +    R G  +    API+  +  V P +P  P   H+ AN     +++ WE
Sbjct: 22435 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 22490

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
                     G +I       ++ N++    E  V   + +     L  GLEY    Y +  
Sbjct: 22491 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22548

Query: 1251  ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
                 K  + S PI       V  P     T++   T+ + W+ P       +  +++   
Sbjct: 22549 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 22606

Query: 1304  PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
             PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+  R
Sbjct: 22607 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 22666

Query: 1354  Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
                   K  LD+    D   I A S  V   A    P   I   +     +       + 
Sbjct: 22667 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 22726

Query: 1405  RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
                 +   I   + +   +Y +++   +G +   +++     V D P     L V   T 
Sbjct: 22727 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 22782

Query: 1462  TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
                 ++W  P       + +Y +   ET   S +    V G   T +  ++ L    +Y 
Sbjct: 22783 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 22839

Query: 1516  ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
               V AV   G   P  S+PI       I  P  + +        I ++W    S     +
Sbjct: 22840 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 22899

Query: 1570  TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             + Y V    K     T+  K      T + +  L    +Y   V A N +G S+P   + 
Sbjct: 22900 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 22959

Query: 1629  VT-------TIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK- 1676
                      T   P+  +    T  S+S  WT P       + GY + +  K+     + 
Sbjct: 22960 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 23019

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTD 1734
               N    ++   V  L +  KY   V A+     S  ++ +  +  +E +  P    + D
Sbjct: 23020 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD-LELAD 23078

Query: 1735  ATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
               + T+TI        +        P       G     R I     SY++  +     Y
Sbjct: 23079 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 23138

Query: 1790  KIYLYTL---NDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPR----ARIT 1841
                 YT+   N + + S  V+        P  +++    + +S+ ++W+ P     A + 
Sbjct: 23139 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVN 23198

Query: 1842  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP------- 1894
              YI++  +      + V   +   T   I+GL  GT Y   V+        EP       
Sbjct: 23199 NYIVEKREAAMRAFKTVTT-KCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAV 23257

Query: 1895  ------LIGRKKTGQEALSQT-TISWA-PFQDTSE----YIISCHPVGTDEEPLQFRVPG 1942
                   L+  K    +    T T++W  P  D       Y++     GT+       +  
Sbjct: 23258 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23317

Query: 1943  TSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTV 2002
             T    T+T L  G  Y   + A  ++   + RE V  V  +V +    PT D    P   
Sbjct: 23318 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAV--TVQDLRVLPTIDLSTMPQKT 23375

Query: 2003  SHYAVG 2008
              H   G
Sbjct: 23376 IHVPAG 23381



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 20155 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20209

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 20210 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20269

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 20270 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20327

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 20328 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20384

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 20385 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20442

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 20443 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20502

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 20503 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20558

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 20559 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20618

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 20619 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20678

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 20679 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20734

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 20735 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20792

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 20793 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20851

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 20852 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20910

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 20911 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20970

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 20971 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21087

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 21088 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21144

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
             T E+ +  L+        V+A+N  G S P+      TI  P  +K   +TP   LS   
Sbjct: 21145 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 21194

Query: 1653  TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
               P  Q+T   G+ V +    K  P   I+   D   +  S  +  +K E  +  ++K+ 
Sbjct: 21195 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21254

Query: 1709  LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
                   +             V  T+  + PP +     R  +    ++ +SW    +   
Sbjct: 21255 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21314

Query: 1751  --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
               IT + ++      QT  +       R ++ +  L    +Y+  +   N    S P+V 
Sbjct: 21315 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21373

Query: 1808  DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
                 A         P        T + + ++W  P     + +TG+ ++ ++  S   + 
Sbjct: 21374 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 21433

Query: 1858  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             V        E   TGL  G +Y   V A  +   S P
Sbjct: 21434 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21470



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 9120 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9177

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9178 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9230

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9231 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9284

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9285 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9344

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9345 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9404

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9405 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9436



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24354 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24408

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24409 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24468

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24469 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24528

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24529 CENLGGESEWSEISEPI--TPKSD 24550



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24737 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24794

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24795 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24854

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24855 EVDETREVSMT 24865



 Score = 35.8 bits (81), Expect = 0.47
 Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)

Query: 1534  ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
             + +  + + DKP+   V + +  NS  + W P +    S +T Y V           +  
Sbjct: 24343 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24402

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
             ++    T   I  L     Y   V AQN  G S PL  ++V  I +P +          T
Sbjct: 24403 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24462

Query: 1642  QVTPTSLSAQWTPP 1655
              VT  S    W PP
Sbjct: 24463 AVTKDSCVVAWKPP 24476


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score =  149 bits (376), Expect = 3e-35
 Identities = 294/1431 (20%), Positives = 527/1431 (36%), Gaps = 186/1431 (12%)

Query: 607   SSSGPVEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGR 653
             S S  +++ + + P  P S  I           W  P     S I+ YI+  R + S   
Sbjct: 12879 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKR-ETSRPN 12937

Query: 654   WKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
             W + +    + S +++ L  G  Y+ ++ +  +YG                PV +     
Sbjct: 12938 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYG-------------VGDPVFTEPAIA 12984

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLP 769
             +     P       ++ IT     VSW   +D     ++G+ +E   ++  +  +    P
Sbjct: 12985 KNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKP 13044

Query: 770   STATSVNIPDLLPGRKYIVNVYQISE--DGEQSLILSTSQTTAPDAPPDPTV-DQVDDT- 825
                 ++    L  G +Y   V  I++   G+ S     +    P  PP P    +V DT 
Sbjct: 13045 IIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTT 13104

Query: 826   --SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT--LSDLQPGVQYN 877
               S+ + W +P     +PI GY +    +   +    NLP+        ++ L    QY 
Sbjct: 13105 RSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQ 13164

Query: 878   ITIYAVEENQESTPVVIQQETTGTPRSDTVPSP----RDLQFVEVTDVKVTI-MWTP--- 929
               +YAV +   S P  +  +    P+   +P       DL+   +    VT+ ++ P   
Sbjct: 13165 FRVYAVNKIGYSDPSDVPDKHY--PKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKG 13222

Query: 930   -PESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSP-GVTYYFKVFAVSHGRES 986
              P   +T  + +V   NL    G  +  +  +TF     ++      Y      S G++ 
Sbjct: 13223 RPPPKITWSKPNV---NLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 13279

Query: 987   KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY 1042
               +  +       P N+     +  +  V W PP     + I  Y +      R      
Sbjct: 13280 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13339

Query: 1043  NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
                 S + + + NL+    Y   + A               V  +  PG  +      V+
Sbjct: 13340 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 13399

Query: 1100  ETTIVITWTPAPR------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
             +++  I W           IG+ +     +  +  R + S S       LT G EY + +
Sbjct: 13400 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSAKDLTEGKEYTFRV 13458

Query: 1154  QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL-------------------TVS 1194
                 +  E     +  V        +L L+  PD   L                   +VS
Sbjct: 13459 SAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13518

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD-NLSPGLEYNVSVYTVKDD 1253
             W++   P  T  R++             E    + +   +D   S   +Y +++  V   
Sbjct: 13519 WKKGEDPLATDTRVSV------------ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 13566

Query: 1254  KESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             KE   IS  ++     PT  ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 13567 KEGT-ISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13625

Query: 1310  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1363
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 13626 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13684

Query: 1364  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 13685 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13744

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS----DVPRDLEVVAATPTSLLISWDAPAVTV 1475
              G EY   ++A+N        +  +  V+    D P   EV+  T  S+ + W  P    
Sbjct: 13745 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13804

Query: 1476  RY----YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
              +    Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 13805 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 13864

Query: 1532  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1575
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 13865 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 13924

Query: 1576  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAP 1635
                   P      T+ P  + +TI+          ++ A NP G     V+  V  +P P
Sbjct: 13925 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 13978

Query: 1636  TD-LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVS 1690
                ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V +
Sbjct: 13979 PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14037

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRT 1746
              L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+ 
Sbjct: 14038 KLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKR 14097

Query: 1747  KTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLN--- 1797
               +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N   
Sbjct: 14098 PVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAG 14156

Query: 1798  ----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1849
                   A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K
Sbjct: 14157 IGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 14216

Query: 1850  PGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
              G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14217 VGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14264



 Score =  148 bits (373), Expect = 7e-35
 Identities = 287/1339 (21%), Positives = 500/1339 (37%), Gaps = 166/1339 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 22723 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22781

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 22782 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22831

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 22832 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 22888

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 22889 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 22948

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 22949 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23008

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 23009 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23060

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 23061 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23119

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 23120 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23177

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 23178 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23236

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 23237 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23296

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 23297 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23356

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 23357 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23414

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 23415 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23474

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 23475 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23534

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 23535 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23594

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 23595 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23646

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 23647 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23705

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 23706 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23764

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 23765 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23821

Query: 1629  VTTIPAPTD--------LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK 1676
               T   P +         +   VT +S+S  W+ P      ++TGY +          ++
Sbjct: 23822 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 23881

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKD---TLTSRPAQGVV--TTLENVSPPRRAR 1731
                    ++   V+GL+   +Y+  + A  D   + TS  ++ VV     +  S P    
Sbjct: 23882 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 23941

Query: 1732  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQP 1785
             +   ++ ++T+ W        + I G+ V+    +G +  +++ K  +  + +TI GL  
Sbjct: 23942 ILSISKDSVTLQWEKPECDGGKEILGYWVE-YRQSGDSAWKKSNKERIKDKQFTIGGLLE 24000

Query: 1786  GTDYKIYLYTLNDNARSSP 1804
              T+Y+  ++  N+   S P
Sbjct: 24001 ATEYEFRVFAENETGLSRP 24019



 Score =  138 bits (347), Expect = 7e-32
 Identities = 290/1321 (21%), Positives = 498/1321 (37%), Gaps = 189/1321 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13293 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13349

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13350 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13394

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13395 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13451

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13452 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13511

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13512 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13569 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13621

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13622 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13680

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13796

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 13797 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13856

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 13857 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 13915

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 13916 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 13968

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 13969 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14018

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS------P 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 14019 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14078

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 14079 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14138

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 14139 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14198

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 14199 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14258

Query: 1526  -DSPASSKPISINYRT---EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 14259 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14318

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-D 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V   P P  +
Sbjct: 14319 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14376

Query: 1638  LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSS---SVVVS 1690
             L+ T +T  S++  W  P +    ++T Y V    +++    K  + A       +  V+
Sbjct: 14377 LRPTDITKDSVTLHWDLPLIDGGSRITNYIV----EKREATRKSYSTATTKCHKCTYKVT 14432

Query: 1691  GLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISW---- 1744
             GL    +Y   V A  +     P +    V   E  SPP    + D T++T++++W    
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPK 14492

Query: 1745  RTKTETITGFQVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1803
                   ITG+ ++A    + Q     T+K       +  L  G +Y   +  +N   RS+
Sbjct: 14493 HDGGSKITGYVIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSA 14550

Query: 1804  P 1804
             P
Sbjct: 14551 P 14551



 Score =  129 bits (323), Expect = 4e-29
 Identities = 290/1339 (21%), Positives = 478/1339 (35%), Gaps = 173/1339 (12%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7279 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7337

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7384

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7385 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7444

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7445 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7504

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7562

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7563 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7622

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7623 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7681

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7682 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7741

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7742 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7801

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7802 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7860

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 7861 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 7914

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 7915 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 7973

Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
             I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 7974 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8033

Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
              +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8093

Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
             TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 8094 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8151

Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
            EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 8152 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8211

Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
              IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 8212 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8271

Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
            +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 8272 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8331

Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 8332 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8391

Query: 1624 LVQTAVTT------IPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGP 1674
             V   +          AP       VT  S+  +W  P      + GY +       T  
Sbjct: 8392 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8451

Query: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR--PAQGVVTTLENVSPPRR--A 1730
             +      ++    V GL+    Y   V A       +  P     T  + +SPP     
Sbjct: 8452 SRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP 8511

Query: 1731 RVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQP 1785
            RVTD + TTI + W          I G+ VD          + T K   VR YT+  ++ 
Sbjct: 8512 RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 8571

Query: 1786 GTDYKIYLYTLNDNARSSP 1804
            G DYK+ +  +N      P
Sbjct: 8572 GADYKLRVSAVNAAGEGPP 8590



 Score =  129 bits (323), Expect = 4e-29
 Identities = 261/1302 (20%), Positives = 465/1302 (35%), Gaps = 162/1302 (12%)

Query: 716   TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--- 772
             TP  P+  T   V EI+  S  V+W           + Y + +   E +     +T    
Sbjct: 13289 TPGPPVNVT---VKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSK 13345

Query: 773   TSVNIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  + +L  G+ Y   V     Y I + GE    +  SQT  P    D  V  V  +S 
Sbjct: 13346 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV--DLKVRSVSKSSC 13403

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
              + W +P +     I GY + +    E +  +  +   +   +  DL  G +Y   + A 
Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAE 13461

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              EN E TP     E T   R D V    DL+ +        + +   E++    ++ +  
Sbjct: 13462 NENGEGTP----SEITVVARDDVVAPDLDLKGLP------DLCYLAKENSNFRLKIPIKG 13511

Query: 944   VNLPGEHGQRL--PISRNTFAEVTGLSPGVTY------------YFKVFAVSHGRESKPL 989
                P    ++   P++ +T   V   +   T             Y        G +   +
Sbjct: 13512 KPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 13571

Query: 990   TAQQTTKLDAPTN-LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNV 1044
             + +   K   PT  ++F   T   + ++W PP+    ++IT Y L    +   +      
Sbjct: 13572 SIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCAS 13631

Query: 1045  GPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKATGVFTTLQ---PGSSIPPYNTEVT 1099
                 + + +  L    EYT  + A    G  E  K+  +        P +  PP   +V 
Sbjct: 13632 AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVR 13691

Query: 1100  ETTIVITWTPAPRIG--------FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
               ++ +TWT   + G         +   R S   +   +         V+GLT G+EY +
Sbjct: 13692 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13751

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTTPD---ITGY 1206
              +  +         + ++ V  L P  P       N     +T+ W          +TGY
Sbjct: 13752 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 13811

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEYNV---------SVYTVKDDKE 1255
              +       +   S  +  H +   C F   +L  G +Y           ++    +  E
Sbjct: 13812 IVEKRDLPSK---SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTE 13868

Query: 1256  SVPISD-----TII--PAVPPPTDLRFTN-IGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
             ++   D     TI+  P +     ++  + I  + + +   P P    +       P   
Sbjct: 13869 TIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP--- 13925

Query: 1308  EEDVAELSISPSDNAVVL--TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD---SPT 1362
               D+ +++ +P+ + + +         EY ++ ++ +     T +   + T LD    P 
Sbjct: 13926 -SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF----GTKVEHVKVTVLDVPGPPG 13980

Query: 1363  GIDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTN 1417
              ++ S+++A   T+ W  P     + I  Y + +            + +   R+    T 
Sbjct: 13981 PVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH--VATK 14038

Query: 1418  LTPGTEYVVSIVALN--GREE----SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L  G EY+  + A+N  G+ E     P+ +  +      P   EV   T  +  +SW  P
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14098

Query: 1472  A----VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    +  Y +   E      V+    P S     ++GL+ G  Y   V A    G  
Sbjct: 14099 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158

Query: 1528  PASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1580
             P S    S+  +        PS   VTD    S S+ W          +TGY V    K 
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY-VVEHQKV 14217

Query: 1581  GPGPTKTKTAGPDQ--TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL 1638
             G       T G     T+  +  LQ   +Y   + A N +G  +P V      IP    +
Sbjct: 14218 GDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV------IPDVEIV 14271

Query: 1639  KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS------------SS 1686
             +        L A+     V   G  +R+    K  P  E+    D+             S
Sbjct: 14272 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTES 14331

Query: 1687  VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDATETTITISW 1744
               +  +    +Y+   + +     +    G V    L+   P    R TD T+ ++T+ W
Sbjct: 14332 FTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHW 14391

Query: 1745  RTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
                       IT + V+   A  ++    T K    +Y +TGL  G +Y   +   N+  
Sbjct: 14392 DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYG 14451

Query: 1801  RSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1852
                P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY+I+ ++ GS
Sbjct: 14452 IGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS 14511

Query: 1853  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                  +   +    E  +  L  G EYT  V+A+ +  +S P
Sbjct: 14512 DQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAP 14551



 Score =  128 bits (321), Expect = 7e-29
 Identities = 268/1266 (21%), Positives = 457/1266 (36%), Gaps = 165/1266 (13%)

Query: 758  EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
            E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 6939 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 6994

Query: 815  PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
             +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 6995 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7054

Query: 871  QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
              G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 7055 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7114

Query: 931  E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 7115 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7173

Query: 987  KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
            KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7228

Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 7229 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7281

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
             V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 7282 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7338

Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
             V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 7339 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7397

Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 7398 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7456

Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPAVPP--PTDLRFTNIGPDTMRVTWAPPP-- 1291
               V         K  K + P  I D I P  PP  PT     ++G  ++R+ W  P   
Sbjct: 7457 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT---VKDVGKTSVRLNWTKPEHD 7513

Query: 1292 -SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE---- 1346
                + ++++       +E V      P+    +L  L+ G EY   V +V +  E    
Sbjct: 7514 GGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-LLPGLMEGQEYSFRVRAVNKAGESEPS 7572

Query: 1347 --STPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG 1399
              S P+  R+K    S P  ++  +IT N+  + W  P     + IT Y +        G
Sbjct: 7573 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7632

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG-------REESPLLIGQQSTVSDVPR 1452
                D         T+T LT G+ YV  + A N          E  +L     T    P 
Sbjct: 7633 WQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7691

Query: 1453 DLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1508
             L VV  T   + + W+ P       ++ Y I   E  G   V+     G      ++ +
Sbjct: 7692 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7751

Query: 1509 KPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDNSISVKWLP- 1564
              G +    V A    G G     ++ +SI   T    P   + VTD     I++ W P 
Sbjct: 7752 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP 7811

Query: 1565 ---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI-EGLQPTVEYVVSVYAQNPSGE 1620
                 SP+ GY V   P       +  +      +  + EG+ P  EYV+ V A N  G 
Sbjct: 7812 EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV 7871

Query: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
            S+P  + +   +    D K T    T          + + G ++ +    +  P+  ++ 
Sbjct: 7872 SEP-SEISENVVAKDPDCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSW 7923

Query: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT-TLEN---------------- 1723
              D   V  S  +      +S + L+   + R   G+ T TLEN                
Sbjct: 7924 HKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982

Query: 1724 VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1779
              P +  + +D T+++  ++W          I  + ++   A  +T I      +  S+T
Sbjct: 7983 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8042

Query: 1780 ITGLQPGTDYKIYLYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1832
            +  L P  +Y   +  +N          ++  +  D     D P ++     T  ++ ++
Sbjct: 8043 VKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTIT 8102

Query: 1833 WQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1888
            W+PP     ++I GYII+    G    +        +   T  GLE G EY   V A   
Sbjct: 8103 WKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENA 8162

Query: 1889 NQKSEP 1894
               SEP
Sbjct: 8163 AGISEP 8168



 Score =  128 bits (321), Expect = 7e-29
 Identities = 299/1394 (21%), Positives = 524/1394 (37%), Gaps = 194/1394 (13%)

Query: 604   TYPSSSGPVEVFIT----ETPSQP----------NSHPIQWNAPQ---PSHISKYILRWR 646
             T  +SSG    F+T    +TPS P          +S  I W  P     S I  YI+  R
Sbjct: 16517 TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKR 16576

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
                    +       H NS+ I  L+ G  Y  ++ +  +YG             T+ P+
Sbjct: 16577 EATRKS-YAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-------LPAQTADPI 16628

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
                 V        P      +V ++T +S  +SW           ++Y +  +    +  
Sbjct: 16629 KVAEV--------PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW 16680

Query: 767   DLPSTATSVN--IPDLLPGRKYIVNVYQISEDGE---QSL---ILSTSQTTAPDAPP--- 815
                +   S+   I +L  G +Y+  V  ++E G    +SL   I++      PD  P   
Sbjct: 16681 SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFS 16740

Query: 816   DPTVDQVDDTSIVVRWS-RPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP-- 872
               +V    D  I V  S RP+  IT  +          +T +N+ ++ +  TLS  +   
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVTDSLDLTTLSIKETHK 16797

Query: 873   --GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
               G QY IT+  V   + ++  ++  +    P+         ++F +V+   +T+ W PP
Sbjct: 16798 DDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGP-------VKFDDVSAESITLSWNPP 16850

Query: 931   ----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAV-----S 981
                    +T Y V                ++R T  +VT L  G  Y F++FA      S
Sbjct: 16851 LYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTL-KVTKLKTGTEYQFRIFAENRYGQS 16909

Query: 982   HGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTRR 1036
                ES P+ AQ   K   P    F    +  +++++W  P     + + GY L      R
Sbjct: 16910 FALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE--RKER 16967

Query: 1037  GQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI 1091
                    V  ++   +++  +NL+   EY   + A  I G  ++ K +  +    P    
Sbjct: 16968 NSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD-- 17025

Query: 1092  PPYNTE---VTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             PP   E   V    I + WT     G  +       G    +     G  + +  T  +E
Sbjct: 17026 PPGTPEPIMVKRNEITLQWTKPVYDGGSMIT-----GYIVEKRDLPDGRWMKASFTNVIE 17080

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPTNL-------------HLEANP---DTGVL 1191
               +T+  L + Q  +  ++ K     +S P++               +  +P   DT V+
Sbjct: 17081 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVV 17140

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS--------PGLEY 1243
                       D+ G  + T     +    +EE    +  +  F  L          G +Y
Sbjct: 17141 NAGETFRLEADVHGKPLPTIEWL-RGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199

Query: 1244  NVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPP---PSIDLTNFL 1299
              +    V   K S P++  ++    PP   ++ T +  +   +TW+PP      D+++++
Sbjct: 17200 ILRASNVAGSK-SFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYV 17258

Query: 1300  VRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVY-----EQHESTPLR 1351
             V     K E      ++  S+   N++ +T LL G EYV  + +V      E  ES P+ 
Sbjct: 17259 VE----KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17314

Query: 1352  GRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSG----RPR 1402
              +    L   P  ++ ++I  +S TV W  P     + I GY +       SG    +  
Sbjct: 17315 MKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDR--SGIRWIKCN 17372

Query: 1403  EDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---EESPLLIGQQST----VSDVPRDLE 1455
             + R+   R  + +T LT   EY   + A N     E SP  +  ++         P +  
Sbjct: 17373 KRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAH 17430

Query: 1456  VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV----PGSKSTA-TISGLKP 1510
             +V  T  S+ ++W  P        + Y      +  +E+ +     G + T   IS L  
Sbjct: 17431 IVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTE 17490

Query: 1511  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1567
               +Y I V A+   G   A+S P ++    +++ P ++ +       I V+   S+    
Sbjct: 17491 HQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVRAGGSARIHI 17549

Query: 1568  PVTGY---RVTTTPKNGPGPTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
             P  G     +T + + G    K +   G + T+++I+           +  +N SG    
Sbjct: 17550 PFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 17609

Query: 1624  LVQTAVTTIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINL 1680
              V   V   P  P +L   +V   S    W PP +   G +V+  V  K ++      N+
Sbjct: 17610 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID-GGAKVKNYVIDKRESTRKAYANV 17668

Query: 1681  APDSS--SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDAT 1736
             +   S  S  V  L     Y   V A  +     P + V  V   E  SPP +  +TD +
Sbjct: 17669 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17728

Query: 1737  ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1792
             +T+ ++ W          + G+ V+  P  G        +  V +  +TGL  G +Y+  
Sbjct: 17729 QTSASLMWEKPEHDGGSRVLGYVVEMQP-KGTEKWSIVAESKVCNAVVTGLSSGQEYQFR 17787

Query: 1793  LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1852
             +   N+  +S P V      +  P   + L   P SL + +     +  G  +K E P  
Sbjct: 17788 VKAYNEKGKSDPRV------LGVPVIAKDLTIQP-SLKLPFNTYSIQ-AGEDLKIEIP-- 17837

Query: 1853  PPREVVPRPRPGVT 1866
                 V+ RPRP ++
Sbjct: 17838 ----VIGRPRPNIS 17847



 Score =  128 bits (321), Expect = 7e-29
 Identities = 307/1365 (22%), Positives = 489/1365 (35%), Gaps = 211/1365 (15%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 17581 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17638

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 17639 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17698

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 17699 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17754

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 17755 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 17812

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 17864

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 17865 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 17922

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 17923 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 17979

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 17980 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18038

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 18039 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18097

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 18098 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18154

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 18155 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18203

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 18204 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18262

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 18263 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18322

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 18323 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18381

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 18382 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18441

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 18442 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18501

Query: 1628  AVTTIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP- 1682
             A+     P++ K T  + +S+S  W+ P       + GY V V  KE           P 
Sbjct: 18502 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--KEAAADEWTTCTPPT 18559

Query: 1683  --DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP--------RRA 1730
                     V+ L   T+Y   + A+       PA   G V   E + PP        R+ 
Sbjct: 18560 GLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKV 18619

Query: 1731  RVTDATETT---ITISWR----TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1783
              V  A+ T    +TI  R     K E   G   D       +     +  +V  +     
Sbjct: 18620 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRF----- 18674

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR--- 1837
                 D   Y  TL +N+ S    ++    +D+PS   NL       +S+ +SW+PP    
Sbjct: 18675 ----DSGRYNLTLENNSGSKTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDG 18729

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT--ITGLEPGTEYTIYVIALKNN----- 1889
              A+IT YI++  +     R+         T+ T  I  L+ G  Y   V+A         
Sbjct: 18730 GAKITNYIVEKRET---TRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLP 18786

Query: 1890  -------QKSEPLI--GRKKTGQEALSQTTISWA-PFQDTSE----YIISCHPVGTDEEP 1935
                    + SEP +  GR        +  TI W  P  D       Y++     G+++  
Sbjct: 18787 AETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS 18846

Query: 1936  LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 1980
                +V   +  AT++GLT G  Y   V A+ ++ R   R+  V V
Sbjct: 18847 TCTQVK--TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 18889



 Score =  127 bits (318), Expect = 2e-28
 Identities = 274/1320 (20%), Positives = 485/1320 (36%), Gaps = 204/1320 (15%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 11808 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11866

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 11867 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 11926

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 11927 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 11984

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 11985 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12044

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 12045 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12103

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 12104 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12162

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 12163 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12220

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 12221 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12277

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 12278 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12336

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 12337 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12395

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 12396 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12449

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 12450 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12509

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 12510 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12568

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 12569 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12618

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 12619 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12676

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 12677 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12736

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP--APTD 1637
                 +  TA     Q E T  GL+   +Y           + + + +TAV   P   P+D
Sbjct: 12737 DKWVRCNTAPHQIPQEEYTATGLEEKAQY-----------QFRAIARTAVNISPPSEPSD 12785

Query: 1638  LKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKEINLAPDSSS 1686
                    P ++ A+  PP + L+   +  +T K  T           PM  ++   D + 
Sbjct: 12786 -------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 12838

Query: 1687  V-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG------VVTTLENVSPPRRA 1730
             +    G+ +A +  +    L     KD    T+T+  + G       +  L+   PP   
Sbjct: 12839 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 12898

Query: 1731  RVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
             ++         +SW    E     IT + VD    +     Q +    + S ++  L  G
Sbjct: 12899 KINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEG 12958

Query: 1787  TDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR---FLATTPNSLLVSWQPPR--- 1837
              +Y+  +   N      PV  +   A    D P           T + + VSW+PP    
Sbjct: 12959 HEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDG 13018

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIALKNNQKSEP 1894
              + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A+      +P
Sbjct: 13019 GSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP 13076



 Score =  125 bits (314), Expect = 5e-28
 Identities = 273/1298 (21%), Positives = 464/1298 (35%), Gaps = 152/1298 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 14089 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14147

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 14148 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14195

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 14196 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14253

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 14254 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14310

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 14311 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14364

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 14365 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14424

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 14425 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14483

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 14484 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14541

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 14542 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14601

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 14602 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14661

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 14662 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14721

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMR 1284
               T   L+ GLEY   V           I+   I A     VP PP   + T +  D+M 
Sbjct: 14722 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14779

Query: 1285  VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVVLTNLLPGTEYVVSVSSV 1341
             ++W  P S   +  L  +   K    +   ++S +    N    + L  G  Y   V + 
Sbjct: 14780 ISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAE 14839

Query: 1342  YEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHH 1393
                 +S P +  +       +D P      +IT ++ T+ W  P  T    IT Y +   
Sbjct: 14840 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 14899

Query: 1394  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD 1453
                     + +      N  T++ LT    Y   ++A N        I   S  SD    
Sbjct: 14900 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGA----ISPPSEPSDAITC 14955

Query: 1454  LEVVAATPTSLLISWDAPAVTV--RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1511
              + V A    + + +    +      +R+    +G   P  E++  G +   T       
Sbjct: 14956 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15015

Query: 1512  VDYTITVY----------AVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNS 1557
              D++  +           A T    +P        N +  +D+P      + VT+V    
Sbjct: 15016 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV-LDRPGPPEGPLAVTEVTSEK 15074

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
               + W P      + +  Y V     +    T   +     T++ +  L    EY+  V 
Sbjct: 15075 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASE-VQVTKLKVTKLLKGNEYIFRVM 15133

Query: 1614  AQNPSGESQPLVQTAVTTI------PAPTDLKFTQVTPTSLSAQWTPPNV----QLTGYR 1663
             A N  G  +PL    V  +        P + + T +T  S+   W  P+     ++  Y 
Sbjct: 15134 AVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI 15193

Query: 1664  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VV 1718
             V    K     +K            VSGL    +YE  + A      S P+         
Sbjct: 15194 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15253

Query: 1719  TTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP 1773
              T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P
Sbjct: 15254 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTP 15310

Query: 1774  DV----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
                    SYTITGL    +YKI +Y +N      P ++
Sbjct: 15311 PAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15348



 Score =  123 bits (308), Expect = 2e-27
 Identities = 261/1315 (19%), Positives = 476/1315 (36%), Gaps = 156/1315 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 12987

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 12988 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13047

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13048 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13107

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13108 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13167

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13168 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13226

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13287 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13344

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13345 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13401

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13402 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13513

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 13514 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13564

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 13565 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13621

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 13622 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13681

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 13682 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13741

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1562
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 13742 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13801

Query: 1563  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 13802 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13861

Query: 1623  PLVQTAVTTI-----PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK- 1676
                ++  T I      APT +         L+ +     + L    +   P  K+   K 
Sbjct: 13862 APSESTETIICKDEYEAPT-IVLDPTIKDGLTIK-AGDTIVLNAISILGKPLPKSSWSKA 13919

Query: 1677  ----------EINLAPDSSSVVVSGLMVATKYEVSVYALKDT--LTSRPAQGVVTTLENV 1724
                       +I   P SS + +     AT+ +   Y +  T    ++     VT L+  
Sbjct: 13920 GKDIRPSDITQITSTPTSSMLTIK---YATRKDAGEYTITATNPFGTKVEHVKVTVLDVP 13976

Query: 1725  SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP--IQRTIKPDVRS--YTI 1780
              PP    +++ +    T++W    E         +    +T   +   +  D++S  +  
Sbjct: 13977 GPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVA 14036

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQ 1834
             T L  G +Y   +  +N   +  PV  +    +D       P        T N+  VSW+
Sbjct: 14037 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 14096

Query: 1835  PP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
              P     + ITGY ++  +  S       +         +TGL+ G+ Y   V A
Sbjct: 14097 RPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSA 14151



 Score =  120 bits (300), Expect = 2e-26
 Identities = 273/1236 (22%), Positives = 459/1236 (37%), Gaps = 166/1236 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20652

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20653 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20708

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20709 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20765

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20766 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20816

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 20817 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 20875

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 20876 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 20935

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 20936 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 20991

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 20992 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21051

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 21052 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21108

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 21109 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21164

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 21165 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21223

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 21224 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21283

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 21284 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21343

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 21344 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21403

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPAPTD 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T    +P   +
Sbjct: 21404 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVE 21462

Query: 1638  ----------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
                       +K  +        Q  P   ++T ++  V  +++     EI     S+S+
Sbjct: 21463 FGPEYFDGLIIKSGESLRIKALVQGRPV-PRVTWFKDGVEIEKRMN--MEITDVLGSTSL 21519

Query: 1688  VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR---RARVTDATETTITISW 1744
              V     AT+    VY ++    S  A+  +      +P +     R T+ T   +T+ W
Sbjct: 21520 FVRD---ATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21576

Query: 1745  RTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-- 1798
                       IT + ++    +         K + +SYT   L  G +Y+  +  +N   
Sbjct: 21577 DAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFG 21636

Query: 1799  ---NARSSPVVIDAS-TAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEK 1849
                   S PVV     T  DAP        T NS+ ++W  P     + I  YI+ + EK
Sbjct: 21637 VGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREK 21696

Query: 1850  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
               +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 21697 KSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 21732



 Score =  118 bits (295), Expect = 7e-26
 Identities = 345/1615 (21%), Positives = 576/1615 (35%), Gaps = 251/1615 (15%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 22462 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22520

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 22521 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22570

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 22571 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22626

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 22627 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22684

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 22685 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22735

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 22736 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22795

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 22796 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 22855

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 22856 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 22915

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 22916 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 22969

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 22970 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23029

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 23030 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23080

Query: 1222  EEVVHADQS-----SCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTIIPAVPP-- 1269
             E  + A ++     S T   +S  +E  +  + V  +      E    SD ++ +  P  
Sbjct: 23081 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23140

Query: 1270  PTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
             P  L   ++   T+ + W  P       LT +++       E  +  +++ P+     +T
Sbjct: 23141 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23200

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI-TANSFTVHWIAPRATI 1385
             +L  G +Y+  + +  E+  S P        +     +   D+ T    T+H  A R   
Sbjct: 23201 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVE 23260

Query: 1386  TGYRIRHHPE-----HFSGRPR--------EDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
                 I   P       F+G           E     ++ +I  T +    EY + +  + 
Sbjct: 23261 LVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVT 23320

Query: 1433  GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
             G     + +            +++     TS+ ISW+ P            E  G +P+ 
Sbjct: 23321 GTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP------------ELDGGAPLS 23368

Query: 1493  EFTV-------PG--------SKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI 1536
              + V       PG        ++ST   + L  G +Y   V A    G  S   S+ I  
Sbjct: 23369 GYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 23428

Query: 1537  NYRTEIDKPSQ-MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
                  I  P + +Q+ DV  + +++ W P      S VTGY V           +     
Sbjct: 23429 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 23488

Query: 1592  PDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA-PTDLKFTQVT 1644
                T     GL   +EY   V A N      PS  S+P+V       P  P + + T  T
Sbjct: 23489 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 23548

Query: 1645  PTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
              TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y  
Sbjct: 23549 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 23608

Query: 1701  SVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTE 1749
              V A        PA+  G V   E +  P             V       +TI  + K  
Sbjct: 23609 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP- 23667

Query: 1750  TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVI 1807
                 F +      GQ   +R +     ++T   ++     D   Y   L +      V I
Sbjct: 23668 ----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYI 23723

Query: 1808  DASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVV 1858
                  I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    + 
Sbjct: 23724 KVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTID 23782

Query: 1859  PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA------------- 1905
              R R   T   + GL+   EY   V A      S+PL   +    +              
Sbjct: 23783 SRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPE 23840

Query: 1906  -----LSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 1955
                   S  ++SW+  +D      + Y I      TD+     +   T+T  T+TGL   
Sbjct: 23841 VLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPD 23900

Query: 1956  ATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2012
             A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V  +WE
Sbjct: 23901 AEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWE 23955

Query: 2013  RMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2067
             +    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 23956 KPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24002



 Score =  117 bits (294), Expect = 9e-26
 Identities = 153/711 (21%), Positives = 271/711 (38%), Gaps = 74/711 (10%)

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1324
             PP   ++   I   ++ ++W PP       L+ ++V      +      +S S + +   
Sbjct: 23337 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDA-HRPGWLPVSESVTRSTFK 23395

Query: 1325  LTNLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              T L  G EYV  V++        Y Q E    R   +     P  +   D++ +  T+ 
Sbjct: 23396 FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIP-GPPETLQIFDVSRDGMTLT 23454

Query: 1378  WIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1433
             W  P     + +TGY +           R ++VP +      T LT G EY   + A+N 
Sbjct: 23455 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23514

Query: 1434  R-------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITY 1482
             R          P++          P++  V   T TS+ ++W  P       V  Y I  
Sbjct: 23515 RGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEM 23574

Query: 1483  GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542
              +   +   +  T P      T++ L  G +Y   V A    G    +  P ++     +
Sbjct: 23575 QKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23634

Query: 1543  DKPSQMQVTDVQDNSISVKW---LPSSSPVTG--YRVTTTPKNGPGPTKTKTAGPDQT-- 1595
             + P   ++ +     I V+    +  + P+ G  + +    K G   +K       +T  
Sbjct: 23635 EYPDY-ELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHT 23693

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLSAQWT 1653
             E+ I+           +  +N  G+    ++  V   P   +  L++  +   S+   W 
Sbjct: 23694 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23753

Query: 1654  PP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707
             PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A   
Sbjct: 23754 PPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQ 23810

Query: 1708  TLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQVD 1757
                S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ ++
Sbjct: 23811 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIE 23870

Query: 1758  AVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI-D 1808
                 +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  D
Sbjct: 23871 RKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 23929

Query: 1809  ASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPG 1864
                    P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R  
Sbjct: 23930 PFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIK 23989

Query: 1865  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAP 1915
               + TI GL   TEY   V A      S P    ++T     ++ T   AP
Sbjct: 23990 DKQFTIGGLLEATEYEFRVFAENETGLSRP----RRTAMSIKTKLTSGEAP 24036



 Score =  116 bits (291), Expect = 2e-25
 Identities = 283/1346 (21%), Positives = 478/1346 (35%), Gaps = 213/1346 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17656

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17657 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17703

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17704 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17759

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17760 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17819

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 17878

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 17931

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 17932 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 17990

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18108

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18162

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 18163 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18222

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAV-PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 18282 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18340

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 18341 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18520

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 18521 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18568

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 18569 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18624

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 18625 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18681

Query: 1613  YAQNPSGESQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVT 1667
               +N SG     V   V   P AP +L   +V   S++  W PP      ++T Y   + 
Sbjct: 18682 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY---IV 18738

Query: 1668  PKEKTGPMKEINLAPDSSSVV--VSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLEN 1723
              K +T       +  + +     +  L     Y   V A  +     PA+    V   E 
Sbjct: 18739 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 18798

Query: 1724  VSPPRRARVTDATETTITISWRTKTET-----ITGFQVDAVPANGQTPIQRTIKPDVRSY 1778
               PP R  + D T  T TI W  K E+     ITG+ V+ +   G        +      
Sbjct: 18799 PLPPGRVTLVDVTRNTATIKWE-KPESDGGSKITGYVVE-MQTKGSEKWSTCTQVKTLEA 18856

Query: 1779  TITGLQPGTDYKIYLYTLNDNARSSP 1804
             TI+GL  G +Y   +  +N+  RS P
Sbjct: 18857 TISGLTAGEEYVFRVAAVNEKGRSDP 18882



 Score =  115 bits (289), Expect = 4e-25
 Identities = 310/1459 (21%), Positives = 503/1459 (34%), Gaps = 214/1459 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 18275 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18329

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 18330 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18387

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 18388 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18446

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 18447 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC------ 18500

Query: 905   DTVPSPRDLQFVEVTDVK---VTIMWTPP----ESAVTGYRVDVI------------PVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 18501 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18560

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQTTK--- 996
             L G+              VT L     Y F++ A++     +P T      AQ+  +   
Sbjct: 18561 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18609

Query: 997   --LDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
               LDA      V    +T+ +  T    P  ++   +    LT R Q     V  S +  
Sbjct: 18610 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQ---IEVTSSFTML 18666

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 18667 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18726

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 18727 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18842

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPA---VPPP 1270
             ++ ++  +V   +    T   L+ G EY   V  V +   S P  +   +I     + P 
Sbjct: 18843 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 18899

Query: 1271  TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP------------VKNEEDVAELSISP 1318
              +L F               P        V +              V + + V  LSI  
Sbjct: 18900 VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKE 18959

Query: 1319  SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
             +    V      GT  +   +S         +    + G   P  ID  +++ +S T+ W
Sbjct: 18960 ASKEDV------GTYELCVSNSAGSITVPITIIVLDRPGPPGPIRID--EVSCDSITISW 19011

Query: 1379  IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG- 1433
               P       I+ Y I    E  S          +R SI +  LT G+EY   + A N  
Sbjct: 19012 NPPEYDGGCQISNY-IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRY 19070

Query: 1434  -----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRYYRITYGE 1484
                   E S ++     +    P   +VV AT +++L++W  P       V  Y + Y E
Sbjct: 19071 GKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKE 19130

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEI 1542
                    +   +  + +   +SGL  G+ Y   VYA  + G G    S +P+    R   
Sbjct: 19131 RSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA--RDPC 19188

Query: 1543  DKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
             D P Q +VT++   S+S+KW        + +TGY V           K       +T   
Sbjct: 19189 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19248

Query: 1599  IEGLQPTVEYVVSVYAQN-------PSGESQP-LVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
             +  L     Y   V+A+N       PS  + P +V+  V       D+KF  V     + 
Sbjct: 19249 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK-AG 19307

Query: 1651  QWTPPNVQLTGYRVRVTPKEKTGPMKEIN-----LAPDSSSVVVSGLMVATKYEVSVYAL 1705
             +    N  + G  + V    K G   E       ++ D+ +++     +       V  L
Sbjct: 19308 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19367

Query: 1706  KDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTETITGFQVD--AVPAN 1762
             K+   +R        L+   PP     +   T    ++SW    E   G  +D   V   
Sbjct: 19368 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQED-GGADIDYYIVEKR 19426

Query: 1763  GQTPIQRTI---KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV------VIDASTAI 1813
               + +  TI   +  + S  +T L  G +Y   +  +N      P+       +D  T  
Sbjct: 19427 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19486

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               P++L   + T  S+ + W  P     + I+GYII+  +  S     V +         
Sbjct: 19487 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19546

Query: 1870  ITGLEPGTEYTIYVIA-----LKNNQKSEPLI------------GRKKTGQEALSQTTIS 1912
              TGL  G EY   V A     L    ++ PLI             + K      +  TI+
Sbjct: 19547 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIA 19606

Query: 1913  WA-PFQDTSEYIISCHPVGTDEEPLQFRVPGTS---TSATLTGLTRGATYNIIVEAL--- 1965
             W  P  D    I          +   ++    S   T  T++GLT GA Y   V+++   
Sbjct: 19607 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 19666

Query: 1966  --------KDQQRHKVREE 1976
                      D Q  K REE
Sbjct: 19667 GASDPSDSSDPQIAKEREE 19685



 Score =  115 bits (288), Expect = 5e-25
 Identities = 283/1405 (20%), Positives = 509/1405 (36%), Gaps = 159/1405 (11%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18306 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18364

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18365 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18411

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18412 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18470

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18471 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18530

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18531 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18590

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 18591 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18650

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 18651 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18707

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 18708 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18767

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 18768 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 18824

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 18825 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 18884

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 18885 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 18937

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAVPPPTDL 1273
             L+E    + SS    T  ++    + +V  Y +         +VPI+  ++    PP  +
Sbjct: 18938 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 18997

Query: 1274  RFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTN 1327
             R   +  D++ ++W PP       ++N++V     K E        +S + +  ++ +  
Sbjct: 18998 RIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVR 19053

Query: 1328  LLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP 1381
             L  G+EY   V +          ES+ +          P G       T ++  V W  P
Sbjct: 19054 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19113

Query: 1382  ----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----G 1433
                  + + GY + +         + +++  +   + ++ L  G  Y   + A N    G
Sbjct: 19114 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19173

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             +              D P   EV   T  S+ + W  P       +  Y +   E     
Sbjct: 19174 KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGR 19233

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQM 1548
              ++       ++   ++ L     Y   V+A       S  S     I  + +++ P  M
Sbjct: 19234 WLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVM 19293

Query: 1549  QVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIE 1600
                  +D  +  + + L  ++ + G    V +  K+G       +T+    D  T +T++
Sbjct: 19294 MDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK 19353

Query: 1601  GL--QPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT--DLKFTQVTPTSLSAQWTPP- 1655
                 + T +YV+++  +N +G     V   V   P P    L+   +T    S  W  P 
Sbjct: 19354 DCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQ 19411

Query: 1656  ---NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLT 1710
                   +  Y   +  K +T  +       +   +S  V+ L+   +Y   V  +     
Sbjct: 19412 EDGGADIDYY---IVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 19468

Query: 1711  SRPAQGV-VTTLENV---SPPRRARVTDATETTITISW-RTKTE---TITGFQVDAVPAN 1762
               P + V +  L+     SPP    +T  T+ ++T+ W R +++    I+G+ ++    N
Sbjct: 19469 GEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKN 19528

Query: 1763  GQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAI--- 1813
                 ++   KP  D+R  + TGL+ G +Y+  +Y  N    S P     +I A   +   
Sbjct: 19529 SLRWVRVNKKPVYDLRVKS-TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19587

Query: 1814  DAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
               PS  + + +   ++ ++W  P     A ITGY ++Y+K      +   +   G TE T
Sbjct: 19588 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG-TEYT 19646

Query: 1870  ITGLEPGTEYTIYVIALKNNQKSEP 1894
             I+GL  G EY   V ++     S+P
Sbjct: 19647 ISGLTTGAEYVFRVKSVNKVGASDP 19671



 Score =  112 bits (281), Expect = 3e-24
 Identities = 285/1415 (20%), Positives = 486/1415 (34%), Gaps = 167/1415 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 13976 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14030

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 14031 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14077

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 14078 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14137

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 14138 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14197

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 14198 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14256

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 14257 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14316

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 14317 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14373

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 14374 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14432

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14491

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 14492 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14550

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 14551 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14607

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 14608 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14667

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 14668 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14726

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAPR 1382
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 14727 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14786

Query: 1383  AT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
             +     I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 14787 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14846

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 14847 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 14903

Query: 1492  QEFTVPGSKSTA----TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +      +      T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 14904 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 14963

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT------KTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 14964 IKVDVKFKDTVIL-------KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15016

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTTIPAPTD--LKFTQVTPTSLS 1649
                  +             ++ A NP G ++ +    V   P P +  L  T+VT     
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15076

Query: 1650  AQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS--SSVVVSGLMVATKY----- 1698
               W PP      ++  Y V+   K +T  +   N+A +   + + V+ L+   +Y     
Sbjct: 15077 LSWFPPLDDGGAKIDHYIVQ---KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVM 15133

Query: 1699  EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1758
              V+ Y + + L S P   V        PP+   VT  T+ ++ + W           ++ 
Sbjct: 15134 AVNKYGVGEPLESEPVLAV-NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINY 15192

Query: 1759  VPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLNDNARSSPV-------V 1806
             +        QR IK + ++     Y ++GL  G +Y+  +   N    S+P         
Sbjct: 15193 IVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKA 15252

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPR 1862
              D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V  P 
Sbjct: 15253 CDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA 15312

Query: 1863  P-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1896
                 T  TITGL    EY I + A+ +    EP +
Sbjct: 15313 GLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15347



 Score =  110 bits (275), Expect = 2e-23
 Identities = 268/1165 (23%), Positives = 421/1165 (36%), Gaps = 148/1165 (12%)

Query: 709   NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
             N V     P  P+     S  E+T    V+SW    D   G ++   + E+ +  + + +
Sbjct: 10410 NVVDRPGPPVGPV-----SFDEVTKDYMVISWKPPLDD-GGSKITNYIIEKKEVGKDVWM 10463

Query: 769   PSTA----TSVNIPDLLPGRKYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTV 819
             P T+    T+  +  LL G+ YI      N+Y IS+      + +  +   PDAP  P V
Sbjct: 10464 PVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV 10523

Query: 820   DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLP--ETANSVTLSDLQPGV 874
              +V   S +V W++P     PIT Y +    ++      +            + DL  G 
Sbjct: 10524 TEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGC 10583

Query: 875   QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             QY   + A  E     P    +             P + + ++ T   V + W PP    
Sbjct: 10584 QYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDG 10643

Query: 932   -SAVTGYRVDVIPV-NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
              S + GY V+   V +         P S   T  +VTGL  G TY F+V AV+   ES P
Sbjct: 10644 GSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP 10703

Query: 989   LTAQQTT----KLDAPTNLQFVNETDSTVLVRWTPPR--AQITGY---RLTVGLTRRGQP 1039
                 +      +L+ P  +   N      +      R  A I G    ++T     R  P
Sbjct: 10704 AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP 10763

Query: 1040  RQ--YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE 1097
              +   +V P  SK  +RN         SL           +  V    +PG   PP + E
Sbjct: 10764 TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG---PPRDLE 10820

Query: 1098  VTET---TIVITWTPAPRIG------FKLGVRPSQGGE-APREVTSDSGSIVVSGLTPGV 1147
             V+E    +  +TW      G      + +  R     + +P   TS   S     L  G 
Sbjct: 10821 VSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGN 10880

Query: 1148  EYVYTIQVLRDGQERDAPIVN-----KVVTPL---SPPTNLHLEANPDTGVLTVSW---E 1196
             +Y++  +V  + Q    P V      K + PL    PP +LH   + D   +++ W   +
Sbjct: 10881 QYLF--RVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLH-HVDVDKTEVSLVWNKPD 10937

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
             R     ITGY +       Q     + V + +   C    L  G  Y   V    ++   
Sbjct: 10938 RDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE---CVVTGLQQGKTYRFRVKA--ENIVG 10992

Query: 1257  VPISDTIIPA------VPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNFLV 1300
             + + DT IP       VPP  +L    I         T+R    +   P P+   T    
Sbjct: 10993 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT--- 11049

Query: 1301  RYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTGLD 1359
               S +K +E     + + S    +   L   T EY ++VS+       +       T LD
Sbjct: 11050 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTVLD 11105

Query: 1360  ---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT- 1414
                 PTG I+  D+T    T+ W  P+       I +  E    R     V  S +S T 
Sbjct: 11106 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11165

Query: 1415  --LTNLTPGTEYVVSIVALNG------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
               + +L  G EYV  + A N        + +P +   + +    P    V   T  +  +
Sbjct: 11166 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11225

Query: 1467  SWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             SW  P     +    YY      TG    V +  +   K   T  GL  G  Y   V+A 
Sbjct: 11226 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVFAE 11283

Query: 1522  TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
                G S  S     I     I  P      ++ D    +  + W        SP+ GY V
Sbjct: 11284 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVV 11343

Query: 1575  TTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP--LVQTA 1628
                    PG  +      D    Q    + GL    EY   + A N  GE +P  L ++ 
Sbjct: 11344 ECQK---PGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESV 11400

Query: 1629  VTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE-----KTGPM----KEI 1678
             +   I  P +++   VT   +        +++   RV+  P+      K G +    K +
Sbjct: 11401 IAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKVLVREKRV 11458

Query: 1679  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDAT 1736
             +L  D   V +  +  A + +   Y +    +S  AQG  +V  L+   P +  +VT+ T
Sbjct: 11459 DLIQDLPRVELQ-IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVT 11517

Query: 1737  ETTITISWRTKTET----ITGFQVD 1757
             +   TISW    +     IT F V+
Sbjct: 11518 KENCTISWENPLDNGGSEITNFIVE 11542



 Score =  110 bits (274), Expect = 2e-23
 Identities = 279/1352 (20%), Positives = 476/1352 (35%), Gaps = 241/1352 (17%)

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEG-DEPQYLDLPSTATSVNIP--DLLPGR 784
            +T++T  S +++W    D        Y +     D   +  L ST    N     L+P +
Sbjct: 7295 ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK 7354

Query: 785  KYIV-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ---- 835
            +YI      N+Y + E  + S I +  Q   P  P       +   ++ + W  P     
Sbjct: 7355 EYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGG 7414

Query: 836  APITGYRIV-YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE-----ENQES 889
            +PITGY +    P  +       +P    +  +  L    +Y   + A       +  +S
Sbjct: 7415 SPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKS 7474

Query: 890  TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
            T  ++ ++    P     P+ +D     V    V + WT PE    + +  Y ++++   
Sbjct: 7475 TEPILIKDPIDPPWPPGKPTVKD-----VGKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7529

Query: 946  LPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-------LTAQQTTK 996
                    + +P +++    + GL  G  Y F+V AV+   ES+P       L  ++   
Sbjct: 7530 TDEWVRVAEGVPTTQHL---LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7586

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
               P  L+ +N T +T  ++WT P     + IT Y +     RR   +  +     +K  
Sbjct: 7587 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7646

Query: 1053 LRNLQPASEYTVSLVAIKGN--------QESPKATGVFTTLQPGSSIPPYNTEVTETT-- 1102
            +  L   S Y   + A            ++S  A   FTT  PG   PPY   V + T  
Sbjct: 7647 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PG---PPYALAVVDVTKR 7701

Query: 1103 -IVITWTPAPRIGFK------------LGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
             + + W P    G +            LG R  + G+          +  V+ +  G E 
Sbjct: 7702 HVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKT----AGPDCNFRVTDVIEGTEV 7757

Query: 1150 VYTIQVLRDG------QERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVSW---ERS 1198
             + ++   +       +  +   +    +P SPP +LH+    D G   + ++W   E++
Sbjct: 7758 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT---DAGRKHIAIAWKPPEKN 7814

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                I GY +   P   ++   +      D      + + P  EY + V  V     S P
Sbjct: 7815 GGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7874

Query: 1259 --ISDTII---PAVPPPTDLRFTNIG---------PDTMRVTWAPPPSIDLTNFLVRYSP 1304
              IS+ ++   P   P  DL   +I          P   R    P  S       V+ S 
Sbjct: 7875 SEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 7934

Query: 1305 ---VKNEEDVAELSISPSDNA------VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
               +KN+   A L +  S  A      + L N L      ++V  +              
Sbjct: 7935 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI-------------- 7980

Query: 1356 TGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSR 1410
             GL  P   I  SDIT +S  + W  P     G  I H+        R   +P     ++
Sbjct: 7981 -GLPGPCKDIKASDITKSSCKLTWEPPEFD-GGTPILHYVLERREAGRRTYIPVMSGENK 8038

Query: 1411 NSITLTNLTPGTEYVVSIVALN---GRE----ESPLLIGQQSTVSDVPRDLEVVAATPTS 1463
             S T+ +L P  EY   + A+N   G E    ++P++        D P D+EV   T  +
Sbjct: 8039 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEA 8098

Query: 1464 LLISWDAP----AVTVRYY---RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1516
            + I+W  P       +  Y   +I  GE        E  VP    T T  GL+ G +Y  
Sbjct: 8099 MTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR-CNEHLVP--ILTYTAKGLEEGKEYQF 8155

Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ---------DNSIS------VK 1561
             V A    G S  S           ID P  +  T ++         D SIS      + 
Sbjct: 8156 RVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTIT 8215

Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI---------------------- 1599
            W+   + +    +    K    P   +  G  Q E                         
Sbjct: 8216 WIKDENVIVPEEI----KKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8271

Query: 1600 -EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-- 1655
             + L+P    +  +  +N  G ++ P   + + T   P +  F  +  TS+  +W PP  
Sbjct: 8272 RDSLRPD-HGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLD 8330

Query: 1656 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS------VYALKD 1707
                ++  Y +    K K          PDS  +VV+  +   KY V+       Y  + 
Sbjct: 8331 DGGSEIINYTLEKKDKTK----------PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 8380

Query: 1708 TLTSRPAQG---VVTTLENVSP------PRRARVTDATETTITISWRTKTET---ITGFQ 1755
               +R   G   V   L    P      P +  V D T  ++ + W    +    I G+ 
Sbjct: 8381 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYW 8440

Query: 1756 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDAST 1811
            ++    N    + + +++   +++  + GL  G  Y   +   N     + SP   D  T
Sbjct: 8441 LEKREVNSTHWSRVNKSLLNALKA-NVDGLLEGLTYVFRVCAENAAGPGKFSP-PSDPKT 8498

Query: 1812 AID-----APSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
            A D      P   R   T+  ++ + W+PP       I GY +  +  G+          
Sbjct: 8499 AHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8558

Query: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
              V + T+  +  G +Y + V A+    +  P
Sbjct: 8559 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPP 8590



 Score =  109 bits (273), Expect = 3e-23
 Identities = 241/1196 (20%), Positives = 446/1196 (37%), Gaps = 156/1196 (13%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6548 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6607

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6608 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6666

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6667 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6726

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6727 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6786

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6787 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6844

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 6845 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 6903

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 6904 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 6963

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 6964 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7018

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
               +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 7019 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076

Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7136

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
             VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 7137 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7190

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                  V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 7191 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7247

Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
            +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 7248 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7307

Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 7308 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7360

Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
             A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 7361 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7420

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
             V     +     +        T   ++GL    +Y   V A+N +G  +P   T    I
Sbjct: 7421 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7480

Query: 1633 PAPTDLKFTQVTP-------TSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1681
              P D  +    P       TS+   WT P      ++  Y + +    KTG  + + +A
Sbjct: 7481 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEML---KTGTDEWVRVA 7537

Query: 1682 P--DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTD 1734
                ++  ++ GLM   +Y   V A+     S P++    V   E +   SPPR   V +
Sbjct: 7538 EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN 7597

Query: 1735 ATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
             T+ T  + W    +     IT + V+   V   G   +  T+K      T+T L  G+ 
Sbjct: 7598 ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD--TKCTVTPLTEGSL 7655

Query: 1789 YKIYLYTLNDNARS-------SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1837
            Y   +   N   +S       S +  D  T    P  L  +  T   + + W+PP+
Sbjct: 7656 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPK 7711



 Score =  109 bits (273), Expect = 3e-23
 Identities = 287/1351 (21%), Positives = 487/1351 (36%), Gaps = 208/1351 (15%)

Query: 692   VTRFDFTTTSTSTPVTSNTVTGETTPF-------SPLVATSESVTEITASSFVVSW---- 740
             VTRFD    S    +T    +G  T F       SP    + ++ E+   S  +SW    
Sbjct: 18671 VTRFD----SGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18726

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYIVNVYQISEDGE 798
             +     ++ + VE     E     Y  + +  T T+  I +L  G  Y   V   +E G 
Sbjct: 18727 IDGGAKITNYIVE---KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783

Query: 799   QSLILSTSQTTAPDAPPDP----TVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVE 850
               L   T++      PP P    T+  V   +  ++W +P++     ITGY  V     +
Sbjct: 18784 -GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY--VVEMQTK 18840

Query: 851   GSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTP-----VVIQQETTGTPRS 904
             GS       +      T+S L  G +Y   + AV E   S P      VI ++    P  
Sbjct: 18841 GSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKP-- 18898

Query: 905   DTVPSPRDLQFVEVTD-VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP----ISRN 959
              +V  P     V+  + +K+ + +     A   +R D          GQ L     ++ +
Sbjct: 18899 -SVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKD----------GQTLKETTRVNVS 18947

Query: 960   TFAEVTGLS------PGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTV 1013
             +   VT LS        V  Y    + S G  + P+T     +   P  ++    +  ++
Sbjct: 18948 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19007

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR--NLQPASEYTVSLV 1067
              + W PP      QI+ Y   V          + V  +V++  ++   L   SEY   + 
Sbjct: 19008 TISWNPPEYDGGCQISNY--IVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19065

Query: 1068  AIK-----GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR------IGFK 1116
             A          ES      +    PG    P     T++T+++TW           IG+ 
Sbjct: 19066 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19125

Query: 1117  LGVRPSQG---GEAPREVTSDSGSIVVSGLTPGVEY---VYTIQVLRDGQERDAPIVNKV 1170
             L  +        +A + + +D+  + VSGL  G+ Y   VY   +   G+   +      
Sbjct: 19126 LEYKERSSILWSKANKILIADT-QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19184

Query: 1171  VTPLSPP-----TNLHLEA--------NPDTGVLTVSW--ERSTTPDITGYRITTTPTNG 1215
               P  PP     TN+  ++        + D G     +  ER   PD  G  +    TN 
Sbjct: 19185 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPD--GRWLKCNYTNI 19242

Query: 1216  QQGNSLEEVVHADQ-------SSCTFDNLSPGLEYNVSVYTVKDDKE------SVPISDT 1262
             Q+       +  DQ       +    D++S   E +     VKDD E       V   D 
Sbjct: 19243 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSE-STGPIIVKDDVEPPRVMMDVKFRDV 19301

Query: 1263  IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
             I+        +     G     ++WA    I++             E+ A   I  +DN 
Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEI-------------EERARTEIISTDNH 19347

Query: 1323  VVLTNL----LPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTV 1376
              +LT          +YV+++ +V      +   +   K G   P G ++ + +TA   ++
Sbjct: 19348 TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSL 19405

Query: 1377  HWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
              W  P+    A I  Y + +    H +    E  +     S  +T L  G EY+  +  +
Sbjct: 19406 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGV 19463

Query: 1432  NGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRIT 1481
             N        E   +      TV   P  LE+ + T  S+ + W  P       +  Y I 
Sbjct: 19464 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19523

Query: 1482  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1540
               E      V+    P        +GL+ G +Y   VYA    G S P+ + P+ I    
Sbjct: 19524 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAED 19582

Query: 1541  EI---DKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
              +     PS+ ++ D    +I++ W+       +P+TGY V    K+     KT      
Sbjct: 19583 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLR 19641

Query: 1594  QTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTTIPA---PTDLKFTQVT 1644
              TE TI GL    EYV  V + N      PS  S P +       P     ++++ T + 
Sbjct: 19642 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIV 19701

Query: 1645  PTSLSAQWTPPNVQLTGYRVRVTPKE---------KTGPMKEINLAPDSSSVVVSGLMVA 1695
                 S   T P      +R R  P           +T    +   +  S ++  +    +
Sbjct: 19702 KAGASFTMTVP------FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDS 19755

Query: 1696  TKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TI 1751
              KY +++   ++ L++     VV  L+   PP    V D T+ +  +SW          +
Sbjct: 19756 GKYTLTI---QNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPV 19812

Query: 1752  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1811
               + ++   A+ +  +  T   +  SY +T LQ G  Y   +   N+     P       
Sbjct: 19813 KNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGV 19872

Query: 1812  AI----DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 1863
              I      P  L   + + +S+ ++W  P     +RI  Y+++  + G   +  V     
Sbjct: 19873 KITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ--KNWVKCAVA 19930

Query: 1864  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
               T   ++GL   +EY   V A      S+P
Sbjct: 19931 KSTHHVVSGLRENSEYFFRVFAENQAGLSDP 19961



 Score =  108 bits (271), Expect = 4e-23
 Identities = 280/1299 (21%), Positives = 479/1299 (36%), Gaps = 170/1299 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15066 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15183

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15184 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15242

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15299

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15300 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15359

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15360 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15410

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15411 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15470

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15471 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15527

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15528 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15585

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15586 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15642

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 15643 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15696

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 15697 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15754

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 15755 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15813

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 15814 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15872

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 15873 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 15932

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 15933 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 15992

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
                   T   + GL     Y   V A+N +G  S+P   T   T     D         S
Sbjct: 15993 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVD-----PPRIS 16047

Query: 1648  LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL------APDSSSVVVSGLMVATKYEVS 1701
             +  ++    V   G   +V       P+  I          +++ + +     AT   V 
Sbjct: 16048 MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVK 16107

Query: 1702  ----------VYALKDTLTSRPAQGVVTTLENVSPPR-RARVTDATETTITISWRTKTET 1750
                       +   K+    R     V  L+   PP     ++  T    T++W+   + 
Sbjct: 16108 DAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQD 16167

Query: 1751  ITGFQVDAVPANGQTP--IQRTIKPDVR--SYTITGLQPGTDYKIYL-----YTLNDNAR 1801
                  ++ +    +T   +   +  +V+  S  +T L  G +Y   +     Y + +   
Sbjct: 16168 GGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE 16227

Query: 1802  SSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPR 1855
             S PVV      + DAP        T +S++V W+ P     + I GY++ K +K G    
Sbjct: 16228 SEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWT 16287

Query: 1856  EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 R   G     +TGL    +Y   V A      SEP
Sbjct: 16288 RCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16325



 Score =  105 bits (261), Expect = 6e-22
 Identities = 276/1319 (20%), Positives = 468/1319 (35%), Gaps = 210/1319 (15%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 9732  VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9791

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 9792  FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9851

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 9852  TGYWLEMKDTTSKRWKRVNR-DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 9909

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 9910  SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 9969

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 9970  WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10029

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 10030 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10083

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 10084 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10143

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 10144 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10203

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 10204 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10262

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 10263 TEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10319

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE-----L 1314
             PPT          +R       T R +  P P +         S  K+E DV E     +
Sbjct: 10320 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10370

Query: 1315  SISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDIT 1370
               +P+  A+          G   VV  +S   +     +    + G   P G + F ++T
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--PPVGPVSFDEVT 10428

Query: 1371  ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVV 1426
              +   + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+ 
Sbjct: 10429 KDYMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIF 10487

Query: 1427  SIVALNGREESPLLIGQQST------VSDVPRDLEVVAATPTSLLISWDAP--------- 1471
              I A N    S  L+           V D P    V   T  S L++W+ P         
Sbjct: 10488 RIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITN 10547

Query: 1472  -------AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-- 1522
                     ++ R+ R+T        P  +F VP          L  G  Y   V A    
Sbjct: 10548 YILEKRETMSKRWARVTKDPI---HPYTKFRVPD---------LLEGCQYEFRVSAENEI 10595

Query: 1523  GRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVT 1575
             G GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY + 
Sbjct: 10596 GIGDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IV 10652

Query: 1576  TTPKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI 1632
                K G    +     P+   +T+  + GL+    Y   V A N +GES P        +
Sbjct: 10653 EYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP------AHV 10706

Query: 1633  PAPTDLKFTQVTPTS-LSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEINLAPDSS 1685
             P P  +K     P   L A          G  +R++      P  K    KE   AP  +
Sbjct: 10707 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10766

Query: 1686  SVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
              + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR   V++ 
Sbjct: 10767 RIDVTP--VGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEI 10824

Query: 1736  TETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
              + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    L  G  Y
Sbjct: 10825 RKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKHLNEGNQY 10882

Query: 1790  KIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----A 1838
                +   N   R   V        +D       P +L  +      + + W  P     +
Sbjct: 10883 LFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGS 10942

Query: 1839  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
              ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K+E ++G
Sbjct: 10943 PITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------KAENIVG 10992



 Score =  103 bits (257), Expect = 2e-21
 Identities = 257/1326 (19%), Positives = 466/1326 (35%), Gaps = 204/1326 (15%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 12875 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 12934

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 12935 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 12992

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 12993 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13051

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 13052 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13111

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 13112 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13171

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 13172 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13224

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 13225 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13282

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 13283 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13337

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPAVPPPTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 13338 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13393

Query: 1274  RFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
             +  ++   +  + W  P S     +  ++V +   +N+      S+S   +A  LT    
Sbjct: 13394 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE--- 13450

Query: 1331  GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI----T 1386
             G EY   VS+  E  E TP            T +   D+ A    +  +     +    +
Sbjct: 13451 GKEYTFRVSAENENGEGTP---------SEITVVARDDVVAPDLDLKGLPDLCYLAKENS 13501

Query: 1387  GYRIR-----HHPEHFSGRPRED------RVPHSRNSITLTNL------TPGTEYVVSIV 1429
              +R++           S +  ED      RV    +++  T +      +   +Y +++ 
Sbjct: 13502 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 13561

Query: 1430  ALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1485
              + G +E  + I            ++    T  ++ + W  P       +  Y +   ++
Sbjct: 13562 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13621

Query: 1486  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTEI-D 1543
               N  V   +    K+T  ++ L  G++YT  V A    G      S+PI   +  ++ D
Sbjct: 13622 VNNKWVTCASAV-QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13680

Query: 1544  KPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1599
              P    + DV+ +S+S+ W        SP+TGY +    +N     +         +  +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
              GL   +EY   V A N +G  +P + +    A+  I  P   +   +T  S++  WT P
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEP 13800

Query: 1656  NV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL-- 1709
                   +LTGY V          MK  ++     +  V+ L+   KYE  + A K+T   
Sbjct: 13801 KYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRA-KNTAGA 13859

Query: 1710  TSRPAQGVVTTLEN---------VSPPRRARVTDATETTITI-------------SWRTK 1747
              S P++   T +           + P  +  +T     TI +             SW   
Sbjct: 13860 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 13919

Query: 1748  TETITGF---QVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTDYKIYLYTLNDNARSS 1803
              + I      Q+ + P +    I+   + D   YTIT   P GT  +    T+ D     
Sbjct: 13920 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLD----- 13974

Query: 1804  PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVP 1859
                         P  +     +     ++W PP     + I  YI++  +       VV 
Sbjct: 13975 --------VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS 14026

Query: 1860  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG----------------RKKTGQ 1903
                        T L  G EY   V A+ +  K EP+                  + +   
Sbjct: 14027 EDIQSCRHVA-TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSN 14085

Query: 1904  EALSQTTISWA-PFQDTSEYIISCHPVGTDEEPLQF----RVPGTSTSATLTGLTRGATY 1958
                +  T+SW  P  D    I   H    +++ L++    + P +     +TGL  G+TY
Sbjct: 14086 VTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTY 14145

Query: 1959  NIIVEA 1964
                V A
Sbjct: 14146 EFRVSA 14151



 Score =  102 bits (255), Expect = 3e-21
 Identities = 292/1319 (22%), Positives = 464/1319 (35%), Gaps = 205/1319 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10138 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10196

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10197 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10244

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10245 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10304

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10365 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10422

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10423 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10478

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10479 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10538

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10539 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10598

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 10599 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10656

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 10657 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10716

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 10717 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10775

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 10776 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10821

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 10822 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 10880

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 10881 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 10939

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 10940 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 10997

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 10998 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11049

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 11050 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11101

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 11102 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11158

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLK-FTQV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T        + P+P      T +
Sbjct: 11159 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11218

Query: 1644  TPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKY 1698
             T  + +  WT P       +TGY +    +E TG    +N  P +     V+GL     Y
Sbjct: 11219 TENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPIADLKFRVTGLYEGNTY 11276

Query: 1699  EVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKT----- 1748
             E  V+A      S+P+           ++   PP   ++ D +  T  + W TK      
Sbjct: 11277 EFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVW-TKPLSDGG 11335

Query: 1749  ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDYKIYLYTLNDNARSSP 1804
               I G+ V+     G     R  K ++    ++ + GL  G +Y+  +   N      P
Sbjct: 11336 SPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11393



 Score =  101 bits (252), Expect = 7e-21
 Identities = 268/1249 (21%), Positives = 451/1249 (36%), Gaps = 180/1249 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21727

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21728 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21775

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21776 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21835

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 21836 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 21895

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 21896 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 21954

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 21955 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22010

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22011 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22069

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22070 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22127

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22128 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22182

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22183 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22242

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22243 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22302

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 22303 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22359

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 22360 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22418

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22476

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 22477 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22534

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 22535 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22594

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 22595 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22651

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 22652 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22699

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTTIPAPTDLKFTQVT-PTSL 1648
             + YVV+           V A N  G     ES+P+V     TIP+P  +     T    +
Sbjct: 22700 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22759

Query: 1649  SAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEV 1700
               QWT P      +++ Y V    K +   ++   +  D     + + V+ LM    Y+ 
Sbjct: 22760 IIQWTKPESDGGNEISNYLV---DKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 22816

Query: 1701  SVYALKDTLTSRP--AQGVVTTLE---NVSPPRRARVTDATETTITISW 1744
              V A+     S P  A   ++  E      PP   RV D T+ +I+++W
Sbjct: 22817 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAW 22865



 Score =  101 bits (251), Expect = 9e-21
 Identities = 274/1343 (20%), Positives = 479/1343 (35%), Gaps = 185/1343 (13%)

Query: 692   VTRFD---FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSAS 744
             V R+D   +T T  ++  T +         +P    +  VTEIT  S  ++W    +   
Sbjct: 16506 VNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGG 16565

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
               +  + VE     E     Y  + +     S  I  L  G  Y   V   +E G     
Sbjct: 16566 SKIKNYIVE---KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPA 16622

Query: 803   LSTSQTTAPDAPPDP---TVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
              +       + P  P   TVD V   S+ + W++P+       I Y   ++   +E    
Sbjct: 16623 QTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE-KWS 16681

Query: 860   ETAN----SVTLSDLQPGVQYNITIYAVEENQESTP-----------VVIQQETTGTPRS 904
             E A        +++L  G +Y   + AV E   S P           +VI+ +      S
Sbjct: 16682 ECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16741

Query: 905   DTVPSPRDLQFVEVT---DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
              +V   +DL+ +EV      K TI WT           D +P+       Q   I+    
Sbjct: 16742 YSVQVGQDLK-IEVPISGRPKPTITWTK----------DGLPLK------QTTRINVTDS 16784

Query: 962   AEVTGLSPGVTY------YFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTVL 1014
              ++T LS   T+      Y    A   G+++  +      K D P   ++F + +  ++ 
Sbjct: 16785 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 16844

Query: 1015  VRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
             + W PP      QIT Y +    T        +   + +   +  L+  +EY   + A  
Sbjct: 16845 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAEN 16904

Query: 1071  --GNQ---ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGV 1119
               G     ES      +   +PG    P+ T +++ ++VI W        +P IG+ L  
Sbjct: 16905 RYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 16964

Query: 1120  RPSQG---GEAPREVTSDSGSIVVSGLTPGVEYVYTIQ------VLRDGQERDAPIVNKV 1170
             +        +  + +  D+       L  G+EY + +       V +  +  +  +    
Sbjct: 16965 KERNSILWTKVNKTIIHDT-QFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDP 17023

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTT--PTNGQQGNSLEEVV 1225
               P   P  + ++ N     +T+ W +        ITGY +     P       S   V+
Sbjct: 17024 CDPPGTPEPIMVKRNE----ITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17079

Query: 1226  HADQSSCTFDNLSPGLEYNVSVYTV-------KDDKESVPIS---DTIIPAV---PPPTD 1272
                ++  T   L+    Y   V          K    + PI+   +  +P +   P   D
Sbjct: 17080 ---ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRD 17136

Query: 1273  LRFTNIGPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL--- 1325
                 N G +T R    V   P P+I+           K  E+ A   I  +D   +L   
Sbjct: 17137 TIVVNAG-ETFRLEADVHGKPLPTIEWLR------GDKEIEESARCEIKNTDFKALLIVK 17189

Query: 1326  -TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
                 + G +Y++  S+V    +S P+  +       P G +  + +T+   ++ W +P  
Sbjct: 17190 DAIRIDGGQYILRASNVAGS-KSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW-SPPL 17247

Query: 1384  TITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALN------G 1433
                G  I H+   +  + R     V      NS+ +T L  G EYV  I+A+N       
Sbjct: 17248 QDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17307

Query: 1434  REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQ 1492
              E +P+L+     +   P+ LEV      S+ + W+ P        I Y  E    S ++
Sbjct: 17308 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIR 17367

Query: 1493  EFTVPGSKST---ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-----EIDK 1544
                    + T     ++GL    +Y   V A    G    S  P ++ Y+      +   
Sbjct: 17368 WIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS--PATVYYKACDPVFKPGP 17425

Query: 1545  PSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN-GPGPTKTKTAGPDQTEMTI 1599
             P+   + D   NSI++ W        S + GY V     +       T   G   T   I
Sbjct: 17426 PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEI 17485

Query: 1600  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1659
               L    EY + V A N  G  +    T+V     P D    +     L ++     V  
Sbjct: 17486 SKLTEHQEYKIRVCALNKVGLGE---ATSVPGTVKPEDK--LEAPELDLDSELRKGIVVR 17540

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYAL 1705
              G   R+    K  P  EI  + +    +  V +   +  T+  +           +  L
Sbjct: 17541 AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKL 17600

Query: 1706  KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPA 1761
             +++  S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +
Sbjct: 17601 ENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRES 17660

Query: 1762  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS--- 1817
               +     + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS   
Sbjct: 17661 TRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPG 17720

Query: 1818  NLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1873
              +     +  S  + W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL
Sbjct: 17721 KVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGL 17778

Query: 1874  EPGTEYTIYVIALKNNQKSEPLI 1896
               G EY   V A     KS+P +
Sbjct: 17779 SSGQEYQFRVKAYNEKGKSDPRV 17801



 Score =  100 bits (250), Expect = 1e-20
 Identities = 283/1422 (19%), Positives = 504/1422 (35%), Gaps = 178/1422 (12%)

Query: 609   SGPVEVFITETPSQPNSHPI-----------QWNAPQPS---HISKYILRWRPKNSVGRW 654
             S P E  +   P  P   P+           +W  P+ +    I+ YI+  R   + GRW
Sbjct: 14848 SKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPN-GRW 14906

Query: 655   KEATIPGHL-NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG 713
              +A     L N +T+ GL     YE ++I+    G           +  S P  S+ +T 
Sbjct: 14907 LKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG---------AISPPSEP--SDAITC 14955

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ---YLDLPS 770
                  +P +       +        ++   +D         E S++G E +    L++  
Sbjct: 14956 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15015

Query: 771   TATSVNIPDLLPGRKY--IVNVYQISEDGEQSLILSTSQTTAPDAPPDP-TVDQVDDTSI 827
                S N+ +    R+      +   +  G    I +      P  P  P  V +V     
Sbjct: 15016 ADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKC 15075

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             V+ W  P     A I  Y +    +   + T +        + ++ L  G +Y   + AV
Sbjct: 15076 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15135

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              +     P+  +      P     P P++ +   +T   + + W  P+S      ++ I 
Sbjct: 15136 NKYGVGEPLESEPVLAVNPYGPPDP-PKNPEVTTITKDSMVVCWGHPDSDGGSEIINYI- 15193

Query: 944   VNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYFKVFAVSHGRESKPL-------TA 991
             V    + GQR +  ++ T  +    V+GL+ G  Y F++ A +    S P          
Sbjct: 15194 VERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKAC 15253

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYN--VG 1045
                 K   P N + ++ + S++ + W  P     ++ITGY + + L    + +      G
Sbjct: 15254 DTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG 15313

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
                + Y +  L    EY + + A+        A    T       +PP      +   V+
Sbjct: 15314 LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVV 15373

Query: 1106  T--------------WTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
             T                PAP + +      S   +A  E TS    ++V  +       Y
Sbjct: 15374 TIRACCTLRLFVPIKGRPAPEVKWARDHGESLD-KASIESTSSYTLLIVGNVNRFDSGKY 15432

Query: 1152  TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRI 1208
              + V      + A +  +V+    PP +L ++    T V T++W+         I  Y +
Sbjct: 15433 ILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV-TLTWDPPLLDGGSKIKNYIV 15491

Query: 1209  TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPIS 1260
                 +  +  +++    H  ++S   D L  G  Y   V    +          ESV  S
Sbjct: 15492 EKRESTRKAYSTVATNCH--KTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 15549

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSIS 1317
             +  +P    P  +   ++  +++ ++W  P       +  ++V      +++     ++ 
Sbjct: 15550 ERPLP----PGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVK 15605

Query: 1318  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVH 1377
              ++    +T L+ G EY   VS+  E+  S P +                 +  N+FTV 
Sbjct: 15606 VTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTV- 15662

Query: 1378  WIAPRATITGYRIRHHPEHFSGRP------REDRVP----------HSRNSITLTNLTPG 1421
                    + G  ++     F GRP       +D VP           + N+  LT     
Sbjct: 15663 -------LAGEDLKVDVP-FIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDAC 15714

Query: 1422  TE----YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV---- 1473
              E    YVV +    G     L +            +++   T  S+ +SW  P      
Sbjct: 15715 REDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGS 15774

Query: 1474  TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP-ASSK 1532
             ++  Y +   +T   +  Q  +   +++T     LK G +Y   + A    G S   +S+
Sbjct: 15775 SINNYIVEKRDTS-TTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 15833

Query: 1533  PISINYRTEIDKPSQMQVTDVQD-NSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKT 1587
             P    Y  ++  P    V  +   +S+ V+W        S V GY +    +N     K 
Sbjct: 15834 PTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKL 15893

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL----KFTQV 1643
                   QT+    GL+  VEY   V A+N  G  +P   +       P D     +   V
Sbjct: 15894 NKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV 15953

Query: 1644  TPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699
             T  S++ QW  P      ++TGY V      +   MK        +   V+GL+   +YE
Sbjct: 15954 TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYE 16013

Query: 1700  VSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756
               V A     + S P++  G +T  + V PPR +      +T +  +  +       F+V
Sbjct: 16014 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES-------FKV 16066

Query: 1757  DAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SSPVVIDASTAI 1813
             DA       P  + IK D        L+   TD+   L ++ D  R  S   ++ A    
Sbjct: 16067 DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSGNYILKAKNVA 16125

Query: 1814  DAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSP 1853
                S   N++ L               T     ++W+PP     + I  YI++  +    
Sbjct: 16126 GERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRL 16185

Query: 1854  PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
                VV           +T L  G EYT  ++A+      EPL
Sbjct: 16186 VWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 16226



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 336/1557 (21%), Positives = 550/1557 (35%), Gaps = 260/1557 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 9801  GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 9855

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 9856  LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 9911

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 9912  ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 9959

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 9960  VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10017

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 10018 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10074

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 10075 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10127

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 10128 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10186

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 10187 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10246

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKGNQESP 1076
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G Q  P
Sbjct: 10247 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG-QGKP 10305

Query: 1077  KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT---- 1132
                    T +   + P  + +  +   +       R+G    +     G+   +V+    
Sbjct: 10306 SFCTKPITCKDELAPPTLHLDFRDKLTI-------RVGEAFALTGRYSGKPKPKVSWFKD 10358

Query: 1133  ------SDSGSIVVSGLTPGVEYV---------YTIQVLRDGQERDAPIVNKVVTPLSPP 1177
                    D   I  +  T  +E +         Y + V      R       VV    PP
Sbjct: 10359 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPP 10418

Query: 1178  TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS---LEEVVHADQSSCTF 1234
                          + +SW+     D  G +IT      ++      +     + +++C  
Sbjct: 10419 VGPVSFDEVTKDYMVISWKPPL--DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKV 10476

Query: 1235  DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-----VPPPTDLRF-TNIGPDTMRVTWA 1288
               L  G +Y   ++       S P+    + A     VP   D    T +  D+  VTW 
Sbjct: 10477 SKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWN 10536

Query: 1289  PPPS--IDLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE- 1343
              P      +TN+++  R +  K    V +  I P     V  +LL G +Y   VS+  E 
Sbjct: 10537 KPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRV-PDLLEGCQYEFRVSAENEI 10595

Query: 1344  -----QHESTPLRGRQKTGLDSP-TGIDFSDITANSFTVHWIAPR----ATITGYRIRHH 1393
                     S P+  +      SP    +  D T NS  + W  PR    + I GY + + 
Sbjct: 10596 GIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQ 10655

Query: 1394  PEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGREES-------PLLIGQQ 1444
                     R +  P S       +T L  G  Y   ++A+N   ES       P+L+  +
Sbjct: 10656 KVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDR 10715

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVT--VRYYRITYGETGGNSPVQ---EFTVPGS 1499
                 ++  D  +       +  +    A+   V + ++T+ +   ++P +   + T  GS
Sbjct: 10716 LEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10775

Query: 1500  KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDN 1556
             K     +  + G  Y++TV       ++PA SK +S+     +DKP     ++V++++ +
Sbjct: 10776 KLEIRNAAHEDGGIYSLTV-------ENPAGSKTVSVKVLV-LDKPGPPRDLEVSEIRKD 10827

Query: 1557  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             S  + W        S +T Y V          +        ++    + L    +Y+  V
Sbjct: 10828 SCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFA-KHLNEGNQYLFRV 10886

Query: 1613  YAQNPSGESQPLVQTAVTTIPA---------PTDLKFTQVTPTSLSAQWTPPNVQ----L 1659
              A+N  G   P V+T    I A         P DL    V  T +S  W  P+      +
Sbjct: 10887 AAENQYGRG-PFVETP-KPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPI 10944

Query: 1660  TGYRVRVTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1717
             TGY V     ++ G    I     ++   VV+GL     Y   V A        P   + 
Sbjct: 10945 TGYLVEY---QEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIP 11001

Query: 1718  VTTLENVSPPRRARVTDATE-------TTI------------TISWRT---KTETITGFQ 1755
             +   E + PP         E       TT+            T  W T   + +T   + 
Sbjct: 11002 IECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYT 11061

Query: 1756  VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1815
             V+    +    I+  ++ D   Y IT                 NA  S  V    T +D 
Sbjct: 11062 VETDNFSSVLTIKNCLRRDTGEYQITV---------------SNAAGSKTVAVHLTVLDV 11106

Query: 1816  PSN----LRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
             P      +  L  TP  + +SWQPP+    + +  YI++ +        VV       T+
Sbjct: 11107 PGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV-SSGSSKTK 11165

Query: 1868  ATITGLEPGTEYTIYV-----IALKNNQKSEPLIGRKK------TGQEALSQ-----TTI 1911
               I  L+ G EY   V     I +     S P + + K       G+  ++       T+
Sbjct: 11166 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11225

Query: 1912  SWA-PFQDTSEYIISCHPVGTDEEPLQFRV---PGTSTSATLTGLTRGATYNIIVEA 1964
             SW  P  D    I   +    +      RV   P       +TGL  G TY   V A
Sbjct: 11226 SWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFA 11282



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 292/1401 (20%), Positives = 509/1401 (36%), Gaps = 216/1401 (15%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 18781 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18838

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 18839 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 18889

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 18890 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 18946

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 18947 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19003

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 19004 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19063

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 19064 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19117

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 19118 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19176

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 19177 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19234

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 19235 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19285

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 19286 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19342

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 19343 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19401

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 19402 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19459

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 19460 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19519

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 19520 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19578

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 19579 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19636

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 19637 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19692

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19748

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 19749 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19803

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 19804 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19862

Query: 1621  SQPLVQ---TAVTTIPAPTD-LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKT 1672
               P        +T  P+P + L  T ++  S+S  W  P      ++  Y V    K + 
Sbjct: 19863 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 19922

Query: 1673  GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--ENVSPPR-- 1728
               +K       S+  VVSGL   ++Y   V+A      S P + ++  L  E + PP   
Sbjct: 19923 NWVK--CAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID 19980

Query: 1729  ---------RARVTDATETTITISWR-----------TKTETITGFQVDAVPANGQTPIQ 1768
                        R     +  I IS +              +    F  +    N    ++
Sbjct: 19981 MKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLK 20040

Query: 1769  RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNS 1828
              ++  D   Y IT        K ++         + VV+D       P  +  +  T  S
Sbjct: 20041 ESVTADAGRYEITAANSSGTTKAFI---------NIVVLDRPGPPTGPVVISDI--TEES 20089

Query: 1829  LLVSWQPPR----ARITGYII 1845
             + + W+PP+    +++T YI+
Sbjct: 20090 VTLKWEPPKYDGGSQVTNYIL 20110



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 316/1532 (20%), Positives = 551/1532 (35%), Gaps = 236/1532 (15%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 22040 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22098

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 22099 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22154

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 22155 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22206

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 22207 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22264

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 22265 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22324

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 22325 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22378

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 22379 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22437

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 22438 AQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22495

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 22496 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22551

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 22552 DARLHGDLVTIRAGSDLV--------LDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22603

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 22604 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22662

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS---SCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+   +    S     L    EY   V  V
Sbjct: 22663 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22720

Query: 1251  KDDKESVPISDTIIPA-----VPPPTDL-RFTNIGPDTMRVTWAPPPSI---DLTNFLV- 1300
                   VP+    I A     +P P  +      G + + + W  P S    +++N+LV 
Sbjct: 22721 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22780

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 22781 KREKKSLRWTRVNKDYVVY-------DTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22833

Query: 1354  QKTGLDSPTGID-------FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                    P+            D T +S ++ W  P       I GY +    +      R
Sbjct: 22834 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 22893

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 22894 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 22952

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 22953 DDLKKTVTIRAGASL------RLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23005

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 23006 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23064

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 23065 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23123

Query: 1622  QPLVQT---AVTTIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTG 1673
             +P   +    V+ +P  P  L+   VT ++++  W  P      +LTGY +         
Sbjct: 23124 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23183

Query: 1674  PMKEINLAPDSSSVVVSGLMVATKY--------EVSVYALKDTLTSRPAQG--VVTTLEN 1723
              MK + L P      V+ L    +Y        E  V   ++T+T+   Q   V+ T++ 
Sbjct: 23184 WMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL 23243

Query: 1724  VSPPRRARVTDA---TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1780
              + P++     A    E  I I+ R        F    +  + +  ++   K    +   
Sbjct: 23244 STMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRE 23303

Query: 1781  TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR--- 1837
             T ++   +Y + L  +      +  VI           ++       S+ +SW+PP    
Sbjct: 23304 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDG 23363

Query: 1838  -ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA-----LKNN 1889
              A ++GY+++      P    V      VT +T   T L  G EY   V A     + + 
Sbjct: 23364 GAPLSGYVVEQRDAHRPGWLPVSE---SVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23420

Query: 1890  QKSEPLIGRKKTGQEALSQT-----------TISWAPFQD-----TSEYIISCHPVGTDE 1933
              +SE +  R         +T           T++W P +D      + YI+    V  D 
Sbjct: 23421 LQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 23480

Query: 1934  EPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                  +VP T T    TGLT G  Y   V A+
Sbjct: 23481 WVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAI 23512



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 202/957 (21%), Positives = 369/957 (38%), Gaps = 131/957 (13%)

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTV 1013
             T  +VT L  G  Y F+V  V+     +PL +     LD       PT+L+  + T  ++
Sbjct: 19443 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19502

Query: 1014  LVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS--------- 1060
              + W+ P +    +I+GY +     RR +     V   V+K P+ +L+  S         
Sbjct: 19503 TLCWSRPESDGGSEISGYIIE----RREKNSLRWV--RVNKKPVYDLRVKSTGLREGCEY 19556

Query: 1061  EYTVSLVAIKG----NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP------A 1110
             EY V      G    ++ SP          P     P   +  +TTI I W        A
Sbjct: 19557 EYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGA 19616

Query: 1111  PRIGFKLGVRPSQGGEAPREVTSDSGS-IVVSGLTPGVEYVYTIQVLR-----DGQERDA 1164
             P  G+ +  + S   +    + S  G+   +SGLT G EYV+ ++ +      D  +   
Sbjct: 19617 PITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19676

Query: 1165  PIVNKVVTPLSPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTTPTNGQQ 1217
             P + K      P  ++  E      V       +TV +     P++    + + P    +
Sbjct: 19677 PQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNV----LWSKPDTDLR 19731

Query: 1218  GNSLEEVVHADQSSCTFDNLS--PGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
               +  +   + ++S T +N +     +Y +++  V     S+ +   ++    PPT++  
Sbjct: 19732 TRAYVDTTDS-RTSLTIENANRNDSGKYTLTIQNVLS-AASLTLVVKVLDTPGPPTNITV 19789

Query: 1276  TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVAELSISPSDN----AVVLT 1326
              ++  ++  ++W  P +          +PVKN      E   +  +S ++N    +  +T
Sbjct: 19790 QDVTKESAVLSWDVPENDG-------GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 19842

Query: 1327  NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR 1382
             NL  G  Y   VS   E     P   ++   +      P  +  + I+ +S ++ W+ P 
Sbjct: 19843 NLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPE 19902

Query: 1383  ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT---LTNLTPGTEYVVSIVALNGREES-- 1437
                 G RI H+      + +++ V  +    T   ++ L   +EY   + A N    S  
Sbjct: 19903 HD-GGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 19961

Query: 1438  -----PLLIGQQSTVSDV-----PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
                  P+LI +Q    ++     P     V A      +  D P       ++T    G 
Sbjct: 19962 RELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN---LKVDIPISGKPLPKVTLSRDGV 20018

Query: 1488  N-SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                    F    +    TI+ LK  V      Y +T    S  +   I+I     +D+P 
Sbjct: 20019 PLKATMRFNTEITAENLTIN-LKESVTADAGRYEITAANSSGTTKAFINI---VVLDRPG 20074

Query: 1547  Q----MQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1598
                  + ++D+ + S+++KW P      S VT Y +     +    T+  +A   +T M 
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEV-SATVARTMMK 20133

Query: 1599  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----TIPAPTDLKF-TQVTPTSLSAQW 1652
             +  L    EY   + A+N  G S  +    VT     T P P    + T VT  S++  W
Sbjct: 20134 VMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW 20193

Query: 1653  TPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT 1708
               P       + GY + +  +      K   L   ++   V+ +     YE  VYA    
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAA 20253

Query: 1709  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDA--VP 1760
                +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V+   +P
Sbjct: 20254 GVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLP 20313

Query: 1761  ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTAIDA 1815
                 T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T ID+
Sbjct: 20314 DGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDS 20369



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 248/1214 (20%), Positives = 427/1214 (35%), Gaps = 157/1214 (12%)

Query: 730  EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
            +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 7001 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7059

Query: 786  YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
            Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 7060 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7119

Query: 836  APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
            + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 7120 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7179

Query: 896  QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
            +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 7180 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7239

Query: 949  EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
               + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 7240 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7298

Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
            T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 7299 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7358

Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
             + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 7359 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7418

Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
            G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 7419 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7477

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
              +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 7478 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7534

Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
               +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 7535 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7594

Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
              NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 7595 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7653

Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
            + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7713

Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 7714 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7773

Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
             P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 7774 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7821

Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 7822 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 7877

Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 7878 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 7937

Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
            M  + +   +E   SV A         +N  G +   +   V  +P P  D+K + +T +
Sbjct: 7938 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 7997

Query: 1647 SLSAQWTPPNVQ-LTGYRVRVTPKEKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVY 1703
            S    W PP     T     V  + + G    I +    +  S  V  L+   +Y   V 
Sbjct: 7998 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8057

Query: 1704 ALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----E 1749
            A+     ++   G    L+N            PP    V + T   +TI+W+        
Sbjct: 8058 AV-----NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGS 8112

Query: 1750 TITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYT-----LNDNARS 1802
             I G+ ++ + A G+   +R  +    + +YT  GL+ G +Y+  +       +++ +R+
Sbjct: 8113 KIMGYIIEKI-AKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRA 8171

Query: 1803 SPVVIDASTAIDAP 1816
            +P    A   IDAP
Sbjct: 8172 TPPT-KAVDPIDAP 8184



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 272/1303 (20%), Positives = 467/1303 (35%), Gaps = 174/1303 (13%)

Query: 773   TSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
             TS  +  LL G +YI     VN Y + E  E   I +    T P  P    +  V   S+
Sbjct: 19443 TSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESM 19502

Query: 828   VVRWSRPQAP----ITGYRIVYSPSVEGSSTELNL-PETANSVTLSDLQPGVQYNITIYA 882
              + WSRP++     I+GY I            +N  P     V  + L+ G +Y   +YA
Sbjct: 19503 TLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYA 19562

Query: 883   VEENQESTPVVIQQETTGTPRSDT---VPSPRDL-QFVEVTDVKVTIMWTPP----ESAV 934
                 + +  + +  ET+   R++    +PSP    + V+     +TI W  P     + +
Sbjct: 19563 ----ENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPI 19618

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--- 991
             TGY V+    +   +    +   R T   ++GL+ G  Y F+V +V+    S P  +   
Sbjct: 19619 TGYTVEYKKSD-DTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP 19677

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP------------ 1039
             Q   + +        +E   T++V+         G   T+ +  RG+P            
Sbjct: 19678 QIAKEREEEPLFDIDSEMRKTLIVK--------AGASFTMTVPFRGRPVPNVLWSKPDTD 19729

Query: 1040  ---RQYNVGPSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                R Y V  + S+  L     N   + +YT+++  +           V  T  P ++I 
Sbjct: 19730 LRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNIT 19788

Query: 1093  PYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSG--SIVVSGLT 1144
                 +VT+ + V++W        AP   + +  R +   +A   VT++    S  V+ L 
Sbjct: 19789 VQ--DVTKESAVLSWDVPENDGGAPVKNYHIEKREASK-KAWVSVTNNCNRLSYKVTNLQ 19845

Query: 1145  PGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERS 1198
              G  Y + +    +   G   +     K+    SPP  L + +     V +++W   E  
Sbjct: 19846 EGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV-SLTWLKPEHD 19904

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                 I  Y +        Q N ++  V A  +      L    EY   V+       S P
Sbjct: 19905 GGSRIVHYVVEALEKG--QKNWVKCAV-AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 19961

Query: 1259  ISDTIIPAV------PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
               + ++P +      PP  D++  N    T+ V       +D+         V    D  
Sbjct: 19962 -RELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGV 20018

Query: 1313  ELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD--------SPTG 1363
              L  +   N  +   NL    +  V+  +   +  +    G  K  ++         PTG
Sbjct: 20019 PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 20078

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              +  SDIT  S T+ W  P+    + +T Y +    E  +    E     +R  + +  L
Sbjct: 20079 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ETSTAVWTEVSATVARTMMKVMKL 20137

Query: 1419  TPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             T G EY   I A N        + + + +    T    P    V   T  S+ + W  P 
Sbjct: 20138 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPV 20197

Query: 1473  VT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
                   V  Y +   +       +   +    +   ++ +  G+ Y   VYA    G   
Sbjct: 20198 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGK 20257

Query: 1529  ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGP 1584
              S     +      + P  +++TD+  NS+S+ W        S +TGY V          
Sbjct: 20258 PSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW 20317

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ----TAVTTIPAPT--- 1636
             TK       +T+  I GL    +Y   V+A+N  G  S P       T + +   P    
Sbjct: 20318 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20377

Query: 1637  DLKFTQV------TPTSLSAQWT-PPNVQLTGYRVRVTPKE-KTGPMKEINLAPDSSSVV 1688
              L++T+V      T   L A  +  P   +  Y+     KE +T  +  +    D +S++
Sbjct: 20378 PLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYK---DDKELQTNALVCVENTTDLASIL 20434

Query: 1689  VSGLMVATKYEVSVYALK--DTLTSRPAQGVVTTLENVSPPRRA-RVTDATETTITISWR 1745
             +     A +     Y LK  + + S  A   V  L+   PP         T   IT+ WR
Sbjct: 20435 IKD---ADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWR 20491

Query: 1746  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
                +     IT + V+    +       +   +    T T +  G +Y   +  +N    
Sbjct: 20492 PPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGI 20551

Query: 1802  SSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPG 1851
               P+  D+  A +A      P        T NS+ V W  P A     I+GY ++     
Sbjct: 20552 GEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKK 20611

Query: 1852  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTI 1911
             S     V +     T   +TGL   ++Y   V A+               GQ        
Sbjct: 20612 SLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVN------------AAGQ-------- 20651

Query: 1912  SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 1954
                PF + SE+  +  P+     P + R+  ++ S+   G ++
Sbjct: 20652 --GPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSK 20692



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 259/1340 (19%), Positives = 469/1340 (35%), Gaps = 192/1340 (14%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12203 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12260

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12261 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12308

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12309 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12368

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12369 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12428

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12429 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12488

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12489 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12540

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12541 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12600

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12601 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12658

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 12659 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12716

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 12717 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12774

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 12775 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 12834

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 12835 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 12879

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 12880 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 12937

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 12938 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 12997

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 12998 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13057

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 13058 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13112

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 13113 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13171

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 13172 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13228

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 13229 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13286

Query: 1630  TTIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDS 1684
                P  P ++   +++  S    W PP +     +  Y V+    E+      +      
Sbjct: 13287 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSK 13345

Query: 1685  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITI 1742
             +S  V+ L     Y   V+A  +     P +    V   +   P    +V   ++++ +I
Sbjct: 13346 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 13405

Query: 1743  SWRTK----TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1798
              W+         I G+ VD +    +   QR +K     Y+   L  G +Y   +   N+
Sbjct: 13406 GWKKPHSDGGSRIIGYVVDFLTEENKW--QRVMKSLSLQYSAKDLTEGKEYTFRVSAENE 13463

Query: 1799  NARSSP--VVIDASTAIDAP 1816
             N   +P  + + A   + AP
Sbjct: 13464 NGEGTPSEITVVARDDVVAP 13483



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 271/1284 (21%), Positives = 458/1284 (35%), Gaps = 188/1284 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 20923 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 20982

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 20983 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21041

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 21042 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21096

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 21097 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21154

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 21155 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21214

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 21215 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21274

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 21275 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21334

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 21335 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21392

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 21393 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 21448 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21502

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 21503 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21559

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 21560 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21617

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 21618 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21677

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 21678 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21725

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++    P+ ++VTD    ++S++W        
Sbjct: 21726 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21785

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 21786 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21845

Query: 1627  T----AVTTIPAP---TDLKFTQVTPTSLSAQWTPPNVQL-TGYRVRVTPKEK-TGPMKE 1677
             T    AV  + AP    D  F Q       A     +++L   Y+ R TP    + P   
Sbjct: 21846 TGTIKAVDRLTAPELDIDANFKQTHVVRAGA-----SIRLFIAYQGRPTPTAVWSKPDSN 21900

Query: 1678  INLAPD-SSSVVVSGLMV-------ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1729
             ++L  D  ++   S L V       A KY ++V   ++   S+     V  L+   PP  
Sbjct: 21901 LSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV---ENNSGSKSITFTVKVLDTPGPPGP 21957

Query: 1730  ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
                 D T  + T+ W          I  + V+   A+ ++    + K   + + +  L  
Sbjct: 21958 ITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAE 22017

Query: 1786  GTDYKIYLYTLND----NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----R 1837
             G  Y   +  +N+         P  I A+     P  L  + T+ +S +++W  P     
Sbjct: 22018 GVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGG 22077

Query: 1838  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1897
             +RITGY+++  + GS     V          T+  L   TEY   V A  +   SEP   
Sbjct: 22078 SRITGYLLEMRQKGSD--FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP--- 22132

Query: 1898  RKKTGQEALSQTTISWAPFQDTSE 1921
                  +EA S   I     + T++
Sbjct: 22133 -----REAFSSVIIKEPQIEPTAD 22151



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 282/1353 (20%), Positives = 501/1353 (37%), Gaps = 213/1353 (15%)

Query: 710  TVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYL 766
            TV+   TP  P+    E   +I  +S +  W    D      + Y L ++     + +++
Sbjct: 8298 TVSVLDTPGPPINFVFE---DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI 8354

Query: 767  DLPSTAT--SVNIPDLLPGRKYIVNVYQISEDGE-----QSLILSTSQTTAPDAPPDPTV 819
             + ST      ++  L+ G++Y+  V   +  G         +++      PDAP  P V
Sbjct: 8355 VVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8414

Query: 820  DQVDDTSIVVRWSRPQ---APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQY 876
            + V   S++V+W+ P+   +PI GY   +    E +ST  +    +    L     G+  
Sbjct: 8415 EDVTSNSMLVKWNEPKDNGSPILGY---WLEKREVNSTHWSRVNKSLLNALKANVDGLLE 8471

Query: 877  NIT-IYAVEENQESTPVVIQQETTGTPRSDTV--PSPRDLQFVEVTDVKVTIMWTPPE-- 931
             +T ++ V     + P      +      D +  P P   +  + +   + + W PP   
Sbjct: 8472 GLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFN 8531

Query: 932  --SAVTGYRVD--VIPVNLPGEHGQRL-PISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
                + GY VD  ++  N      +++  + + T  E+     G  Y  +V AV+   E 
Sbjct: 8532 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIR---EGADYKLRVSAVNAAGEG 8588

Query: 987  KPLTAQQTT----------KLDAPTNLQFVNETDSTVLVR------------WTPPRAQI 1024
             P   Q  T          +LD             T+ +             WT    ++
Sbjct: 8589 PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL 8648

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
               R+ +           NVG     + K  LR  +    Y ++     G++ +     V
Sbjct: 8649 DKDRVVID----------NVGTKSELIIKDALR--KDHGRYVITATNSCGSKFAAARVEV 8696

Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
            F    P   + P  T       ++ W+       +   GF +  + ++     + + ++ 
Sbjct: 8697 FDVPGPVLDLKPVVTN--RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETER 8754

Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVN----KVVTPLSPPTN----LHLEANPD 1187
                ++GL  G EY +  +V+   +    P V       V PL PPT+     + E    
Sbjct: 8755 SKCDITGLLEGQEYKF--RVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKS 8812

Query: 1188 TGVLTVSWERSTT---PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
            T  +T+ W+   +     I GY I     +      + + +    +S   +NL     Y 
Sbjct: 8813 T--ITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYE 8869

Query: 1245 VSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFL 1299
              V  V +  ES   +P++  I     PPT     ++  DT++V    P  I  D+T   
Sbjct: 8870 FRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLP 8929

Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQKT 1356
            +        E V E    P+D   +    +  +E    +S   +V E   +  +    + 
Sbjct: 8930 MPKIEWSKNETVIE---KPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRL 8986

Query: 1357 GL-------------DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH--PEHFSGRP 1401
            G                P  +  +DI A S  + W AP     G  I H+   +  + R 
Sbjct: 8987 GSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDN-GGSEITHYVIDKRDASRK 9045

Query: 1402 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV------P 1451
            + +    +  ++     +  L P  +Y   + A+N    S      +  + D       P
Sbjct: 9046 KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPP 9105

Query: 1452 RDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGG-------NSPVQEFTVPGSK 1500
               +V+A T  S+L+SW  P       +  Y +   E G         +P+ +  + G +
Sbjct: 9106 GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVE 9165

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPAS--SKP-ISINYRTEIDKPSQMQVTDVQDNS 1557
                +  L  GV Y     A+   G  P S  S P ++ +       PS  +V D   +S
Sbjct: 9166 FN--VPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSS 9223

Query: 1558 ISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTKTAG-PDQTEMTIEGLQPTVE----Y 1608
            IS+ W P +    SP+ GY V    +   G T  K    PD+   T E + P ++    Y
Sbjct: 9224 ISLGWKPPAKDGGSPIKGYIVEMQEE---GTTDWKRVNEPDKLITTCECVVPNLKELRKY 9280

Query: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV-- 1666
               V A N +GES+P   T    IPA TD++        + AQ     V   G ++R+  
Sbjct: 9281 RFRVKAVNEAGESEPSDTTG--EIPA-TDIQEEPEVFIDIGAQ--DCLVCKAGSQIRIPA 9335

Query: 1667 ------TPK---EKTGPMK--------------EINLAPDSSSVVVSGLMVATKYEVSVY 1703
                  TPK   E  G  K              ++  A +SS +++     +   + S+ 
Sbjct: 9336 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSIT 9395

Query: 1704 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAV 1759
            A K+    + A   V  ++   PP+  +V+D T  +  +SW+   +     I G+ ++  
Sbjct: 9396 A-KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR 9454

Query: 1760 PANGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDA- 1815
              +G+   +  + PD  S T  +  L     Y   +   N      PV  I  +TA D  
Sbjct: 9455 TIDGKAWTK--VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPI 9512

Query: 1816 -----PSNLRFLATTPNSLLVSWQPPR----ARITGYIIK---YEKPGSPPREVVPRPRP 1863
                 P  L+    T N++ +SW+PP+    + +T YI++   ++  G+         + 
Sbjct: 9513 YPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKR 9572

Query: 1864 GVTEA--TITGLEPGTEYTIYVIALKNNQKSEP 1894
             V E   T+  L  G EY   V A+     S+P
Sbjct: 9573 DVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9605



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1521 (20%), Positives = 534/1521 (35%), Gaps = 198/1521 (13%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+      P++       P ++ + +     NS  + W  P+    S I +YI+  +
Sbjct: 16616 YGIGLPAQTADPIKVAEVPQPPGKITVDDVTR--NSVSLSWTKPEHDGGSKIIQYIVEMQ 16673

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K+S  +W E      L +  I  L  G  Y  +++++ + G  +         S + P+
Sbjct: 16674 AKHSE-KWSECARVKSLQA-VITNLTQGEEYLFRVVAVNEKGRSD-------PRSLAVPI 16724

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E        + S  V +       +S      T++  +    L +        
Sbjct: 16725 VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG-RPKPTITWTKDGLPLKQTTRINVTD 16783

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDT 825
              L  T  S+       G +Y + V  +   G+++  +       PD P  P   D V   
Sbjct: 16784 SLDLTTLSIKETHKDDGGQYGITVANVV--GQKTASIEIVTLDKPDPPKGPVKFDDVSAE 16841

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
             SI + W+ P       IT Y +    +       ++      ++ ++ L+ G +Y   I+
Sbjct: 16842 SITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIF 16901

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMWTPPE----SAVTG 936
             A  EN+      ++ +          P P    F   ++   + I W  P     S V G
Sbjct: 16902 A--ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIG 16959

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQ 993
             Y ++    N          I  +T  +   L  G+ Y F+V+A   V  G+ SK      
Sbjct: 16960 YHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYV 17019

Query: 994   TTK-LDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSV 1048
                  D P   + +    + + ++WT P     + ITGY +       G+  + +    +
Sbjct: 17020 ARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVI 17079

Query: 1049  -SKYPLRNLQPASEYTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVTE 1100
              +++ +  L     Y   ++A    G    P  +TG  T       P  S+ P   +  +
Sbjct: 17080 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP---KFRD 17136

Query: 1101  TTIV-----------ITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             T +V           +   P P I +  G +   +      + T     ++V        
Sbjct: 17137 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17196

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITG 1205
               Y ++       +  P+  KV+    PP          +   +++W    +    DI+ 
Sbjct: 17197 GQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISH 17256

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPI- 1259
             Y +    T+      +   V  +    T   L  G EY      V+ Y V +  ES P+ 
Sbjct: 17257 YVVEKRETSRLAWTVVASEVVTNSLKVT--KLLEGNEYVFRIMAVNKYGVGEPLESAPVL 17314

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
               +  ++P   PP  L  TNI  D+M V W  P S   +  +      ++   +  +  +
Sbjct: 17315 MKNPFVLPG--PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCN 17372

Query: 1318  P---SDNAVVLTNLLPGTEYV--VSVSSVYEQHESTPLRGRQKT-----GLDSPTGIDFS 1367
                 +D  + +T L    EY   VS  +     E +P     K          PT     
Sbjct: 17373 KRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIV 17432

Query: 1368  DITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT-----NL 1418
             D T NS T+ W  P     + I GY +    E       E ++   +  + +T      L
Sbjct: 17433 DTTKNSITLAWGKPIYDGGSEILGYVV----EICKADEEEWQIVTPQTGLRVTRFEISKL 17488

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-- 1476
             T   EY + + ALN      + +G+ ++V    +  + + A P   L S     + VR  
Sbjct: 17489 TEHQEYKIRVCALN-----KVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAG 17542

Query: 1477  -YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT-----------ITVYAVTGR 1524
                RI     G  +P   ++    + T  +  ++ GV+YT              Y +   
Sbjct: 17543 GSARIHIPFKGRPTPEITWSREEGEFTDKVQ-IEKGVNYTQLSIDNCDRNDAGKYILKLE 17601

Query: 1525  GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKN 1580
               S + S  +++        P  + V +V+ +S  + W P      + V  Y +      
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKREST 17661

Query: 1581  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAP 1635
                     ++   +T   +E L     Y   V A+N  G   P+     V+ A    P P
Sbjct: 17662 RKAYANV-SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSP-P 17719

Query: 1636  TDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVV 1689
               +  T V+ TS S  W  P      ++ GY V + PK  EK   + E  +     + VV
Sbjct: 17720 GKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVC----NAVV 17775

Query: 1690  SGLMVATKYEVSVYALKDTLTSRP-AQGV------VTTLENVSPPRRARVTDATE----- 1737
             +GL    +Y+  V A  +   S P   GV      +T   ++  P       A E     
Sbjct: 17776 TGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE 17835

Query: 1738  ------TTITISWRTKTETI---TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
                       ISW    E +   T   V+    +    I+   K D   YT+T       
Sbjct: 17836 IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG- 17894

Query: 1789  YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYI 1844
                   T  +N   S +V++       P  +RF   + + +++SW+PP      +I+ YI
Sbjct: 17895 ------TATENL--SVIVLEKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYI 17944

Query: 1845  IKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR------ 1898
             ++     +    +V       T   IT L+ GTEY   + A     KS PL  +      
Sbjct: 17945 VEKRDTTTTTWHMV-SATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQY 18003

Query: 1899  --KKTGQE--------ALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQF----RVPGT 1943
               K+ G          +  Q  + W  P  D    II  H    ++  + +    + P  
Sbjct: 18004 PFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 18063

Query: 1944  STSATLTGLTRGATYNIIVEA 1964
              T    TGL  G  Y   V A
Sbjct: 18064 DTKFKTTGLDEGLEYEFKVSA 18084



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 257/1210 (21%), Positives = 441/1210 (36%), Gaps = 158/1210 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20130

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20131 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20188

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20189 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20247

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20248 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20306

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20307 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20363

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20364 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20423

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20424 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20483

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20484 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20540

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 20541 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20600

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 20601 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20660

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 20661 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20716

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 20717 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20776

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 20777 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20832

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 20833 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 20887

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 20888 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 20945

Query: 1616  NPSGESQPLVQT---AVTTIPAP-TDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVT 1667
             N  G  +P   T       +PAP  DL     T TS+   WT P+      +T Y V   
Sbjct: 20946 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21005

Query: 1668  PK-EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS 1725
              K E+T     I+    +  + VS L   +  E  V+A  +   S P   G +T  E + 
Sbjct: 21006 GKGEQTWSHAGIS---KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELII 21062

Query: 1726  PPR---------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ--RTIKPD 1774
              P          +  V       + + ++ K +    +  D +P      ++  +T    
Sbjct: 21063 TPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI 21122

Query: 1775  VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLL 1830
               S      + G  Y + L    DNA     V      +  PS     +RF     +S++
Sbjct: 21123 TLSIKNAKKEHGGKYTVIL----DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 21178

Query: 1831  VSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
             +SW  P       IT Y I+  +      ++V       T   +  L    EY   V A 
Sbjct: 21179 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMV-CSSVARTTFKVPNLVKDAEYQFRVRAE 21237

Query: 1887  KNNQKSEPLI 1896
                  S+PL+
Sbjct: 21238 NRYGVSQPLV 21247



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 307/1485 (20%), Positives = 517/1485 (34%), Gaps = 213/1485 (14%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
             S+ + T +S ++SW            EY +  +G   Q       + +  I ++   ++ 
Sbjct: 20973 SMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEI-EVSQLKEQ 21031

Query: 787   IVNVYQISEDGEQSLI--LSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSRPQAPITGYR 842
              V  +++    E+ L   ++    T  +    P VD  D     + VR          Y+
Sbjct: 21032 SVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYK 21091

Query: 843   IVYSPSVEGSSTELNLPE--------TANSVTLSDLQPGVQYNITIYAVEENQESTPVV- 893
                 PS+      L L E        T N +TLS      ++      + +N      V 
Sbjct: 21092 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 21151

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGE 949
             I   T G P     P    ++F E+    V + W  PE      +T Y ++    +    
Sbjct: 21152 ITVITLGPPSKPKGP----IRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21207

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT-----AQQTTKLDAPTNLQ 1004
                   ++R TF +V  L     Y F+V A +    S+PL      A+   ++  P    
Sbjct: 21208 KMVCSSVARTTF-KVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKP 21266

Query: 1005  FV-NETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPLRNLQP 1058
              + N T   + + W  P     +++TG+ +          ++ N  P S  +Y    L  
Sbjct: 21267 VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVE 21326

Query: 1059  ASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIP--PYNTEVTETTIVITWTPAPRIGF 1115
               +Y   + A       SP     FT        P  P   +VT  TI + W P  R G 
Sbjct: 21327 GLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGG 21386

Query: 1116  K----LGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                    +   QG E  R V  +   +      V+GL+PG  Y + I            I
Sbjct: 21387 SKIVGYSIEKRQGNE--RWVRCNFTDVSECQYTVTGLSPGDRYEFRI------------I 21432

Query: 1167  VNKVVTPLSPPTNLH-------------LEANPD--TGVLTVSWERSTTPDITGYRITTT 1211
                 V  +SPP+                +E  P+   G++  S E      +   R    
Sbjct: 21433 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21492

Query: 1212  PTNGQQGNSLEEVVH---ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--------VPIS 1260
              T  + G  +E+ ++    D    T   +      +  VYTV+    S        V + 
Sbjct: 21493 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKN-----EEDVA 1312
             DT    V P   +RFTNI  + M + W  P +     +T++++             ED  
Sbjct: 21553 DTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC 21609

Query: 1313  ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR------QKTGLDSPTGIDF 1366
             E   + S  A+ L N   G EY   VS+V +     PL         Q T  D+P   + 
Sbjct: 21610 E---AQSYTAIKLIN---GNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21663

Query: 1367  SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPG 1421
             S+IT NS T+ W  P     + I  Y +    +  +   +   + P S     +T LT G
Sbjct: 21664 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21723

Query: 1422  TEYVVSIVALNGREESPL-----LIGQQSTVS--DVPRDLEVVAATPTSLLISWDAPAVT 1474
              EY   ++A N     P      LI  +  V+    P  ++V   + T++ + W  P   
Sbjct: 21724 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21783

Query: 1475  VRYYRITYGETGGNSPVQEFTVPGS----KSTATISGLKPGVDYTITVYAV--TGRGDS- 1527
                  I Y      + + ++    +    K+  T++ L+ G +Y   V A+   G+GDS 
Sbjct: 21784 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 21843

Query: 1528  --PASSKPISINYRTEIDKPSQMQVTDVQDNSISVK-WLPSSSPVTGYRVTTTPKNGPGP 1584
                 + K +      E+D  +  + T V     S++ ++      T   V + P +    
Sbjct: 21844 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 21903

Query: 1585  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQV 1643
                       + +T+E          ++  +N SG         V   P P   + F  V
Sbjct: 21904 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDV 21963

Query: 1644  TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYE 1699
             T  S +  W  P +   G R+     EK    +     I+         V+ L     Y 
Sbjct: 21964 TRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22022

Query: 1700  VSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITG 1753
               V A+ +     P +    +   E  +PPRR  V D ++++  ++W          ITG
Sbjct: 22023 FRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITG 22082

Query: 1754  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1813
             + ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S  I
Sbjct: 22083 YLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22141

Query: 1814  DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT---- 1866
               P         P + L         IT  +I   K GSP    VP   RP P VT    
Sbjct: 22142 KEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVTWKLE 22187

Query: 1867  --------EATITGLEPGTEYTI----------YVIALKNNQ-------------KSEPL 1895
                       +IT  +  T  T+          Y + L+N               +  P+
Sbjct: 22188 EMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPV 22247

Query: 1896  IGRKKTGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 1950
              G  +    +     +SW   +D      + YI+     GT    L        T   +T
Sbjct: 22248 TGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL-VNSSVKRTQIKVT 22306

Query: 1951  GLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE 2010
              LT+   Y+  V +   + R  V + + +           P+  +  + Y VS  A+   
Sbjct: 22307 HLTKYMEYSFRVSS---ENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22363

Query: 2011  WERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGV-----NYKI 2050
             WE     G     + +G+       ++  W  +N V     NYK+
Sbjct: 22364 WEEPYHDGGS---KIIGYWVEKKERNTILWVKENKVPCLECNYKV 22405



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 272/1331 (20%), Positives = 495/1331 (37%), Gaps = 207/1331 (15%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8718  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8775

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8776  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8822

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 8823  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 8883  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 8938

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 8939  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 8999  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9055

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9056  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9115

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9116  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9171

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9172  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9231

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9232  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9287

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9288  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9347

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 9348  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9406

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 9407  CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9465

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 9466  PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9525

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 9526  ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9585

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 9586  EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9645

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 9646  VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9705

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 9706  G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9762

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-----T 1631
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T     +
Sbjct: 9763  N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818

Query: 1632  IP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGP-MKEINLAPDSS 1685
             +P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N  P  +
Sbjct: 9819  VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNRDPIKA 9876

Query: 1686  -----SVVVSGLMVATKYEVSVYALK------DTLTSRPAQGVVTTLENVSPPRR--ARV 1732
                  S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP     +V
Sbjct: 9877  MTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGPPFPKV 9932

Query: 1733  TDATETTITISW----RTKTETITGFQVDAVPANGQTPIQRTIKPDVR--SYTITGLQPG 1786
             TD T+++  + W    +     +TG+ V+     G+   ++    +VR     +TGL+ G
Sbjct: 9933  TDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEG 9991

Query: 1787  TDYKIYLYTLN 1797
               YK  +  +N
Sbjct: 9992  AFYKFRVRAVN 10002



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 301/1456 (20%), Positives = 500/1456 (34%), Gaps = 253/1456 (17%)

Query: 609  SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYI-LRWRP--KNS----VGRWKEATIPG 661
            S P E+   E P+ P S P+  +        K+I + W+P  KN     +G   E    G
Sbjct: 7773 SEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIAWKPPEKNGGSPIIGYHVEMCPVG 7830

Query: 662  -----HLNSYTIKGLK----PGVVYEGQLI----SIQQYGHQEVTRFDFTTTSTSTPVTS 708
                  +NS  IK LK     GVV + + +    ++   G  E +       +   P   
Sbjct: 7831 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD-PDCK 7889

Query: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
             T+  ET     +     S+  +   +  V  VS        +    L+ + D       
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIP-VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDH------ 7942

Query: 769  PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               +  + +P  +     I  +   ++ G  +  ++      P    D     +  +S  
Sbjct: 7943 --ISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8000

Query: 829  VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
            + W  P+     PI  Y +    +   +   +   E   S T+ DL P  +Y   + AV 
Sbjct: 8001 LTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVN 8060

Query: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVD 940
            +      + ++              P D++    T   +TI W PP     S + GY ++
Sbjct: 8061 KVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIE 8120

Query: 941  VIPVNLPGEHGQR------LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
             I     GE   +      +PI   T     GL  G  Y F+V A +    S+P  A   
Sbjct: 8121 KIA---KGEERWKRCNEHLVPILTYT---AKGLEEGKEYQFRVRAENAAGISEPSRATPP 8174

Query: 995  TK----LDAP-----TNLQFVNETDSTVL-----------VRWTPPRAQITGYRL---TV 1031
            TK    +DAP     T+L+ V   D   L           + W      I    +     
Sbjct: 8175 TKAVDPIDAPKVILRTSLE-VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAA 8233

Query: 1032 GLTRRG----QPRQYNVGPSVSKYPLRNLQPASE--------------YTVSLVAIKGNQ 1073
             L RR     Q  +  V P   +  + N +                  Y + +    G  
Sbjct: 8234 PLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIA 8293

Query: 1074 ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS 1133
            ++P    V  T  PG  I     ++ +T+++  W P    G    +  +   E   +   
Sbjct: 8294 KAPCTVSVLDT--PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTL--EKKDKTKP 8349

Query: 1134 DSGSIVVSG-----------LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPT- 1178
            DS  IVV+            L  G EY++ ++   +      P V+K +    P  PP  
Sbjct: 8350 DSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA-ENRFGPGPPCVSKPLVAKDPFGPPDA 8408

Query: 1179 -NLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
             +  +  +  +  + V W   +     I GY +     N    + + + +  +      D
Sbjct: 8409 PDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVD 8467

Query: 1236 NLSPGLEY--NVSVYTVKDDKESVPISDTII---PAVPP-PTDLRFTNIGPDTMRVTWAP 1289
             L  GL Y   V         +  P SD      P  PP P   R T+    T+ + W P
Sbjct: 8468 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8527

Query: 1290 PP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
            P      ++  + V    V   E               +  +  G +Y + VS+V    E
Sbjct: 8528 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8587

Query: 1347 STPLRGRQKTGLD--SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1404
              P   +  T  +   P  ++          +        + G  +R  P   +GRP   
Sbjct: 8588 GPPGETQPVTVAEPQEPPAVELDVSVKGGIQI--------MAGKTLRI-PAVVTGRPVPT 8638

Query: 1405 RV------PHSRNSITLTNLTPGTEYVVS-----------IVALNGREESPLLIGQQSTV 1447
            +V         ++ + + N+   +E ++            I A N           +  V
Sbjct: 8639 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK--FAAARVEV 8696

Query: 1448 SDVPR---DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS----- 1499
             DVP    DL+ V       L++W  P            E  G S +  F +        
Sbjct: 8697 FDVPGPVLDLKPVVTNRKMCLLNWSDP------------EDDGGSEITGFIIERKDAKMH 8744

Query: 1500 ---------KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID------K 1544
                     +S   I+GL  G +Y   V A    G  P    P+ I     +D       
Sbjct: 8745 TWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGP----PVEIGPILAVDPLGPPTS 8800

Query: 1545 PSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            P ++  T+   ++I++ W        SP+ GY +     + P   +        T   +E
Sbjct: 8801 PERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVE 8860

Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPT---SLSAQWTPPNV 1657
             L     Y   V A N  GES+P       ++P    ++  +V PT    LS +     V
Sbjct: 8861 NLDEHQMYEFRVKAVNEIGESEP-------SLPLNVVIQDDEVPPTIKLRLSVRGDTIKV 8913

Query: 1658 QLTGYRVRVTPKEKTG-PMKEINLAPDSSSVVV-SGLMVATKYEVS-------------V 1702
            +  G  V + P + TG PM +I  + + + +   +  +  TK EVS             V
Sbjct: 8914 K-AGEPVHI-PADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971

Query: 1703 YALKDTLTSRPAQGVVTTLENV--------SPPRRARVTDATETTITISWRTKTET---- 1750
               K T T   +  + +   NV        SPPR   VTD    +  ++W    +     
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 9031

Query: 1751 ITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYL-----YTLNDNARSS 1803
            IT + +D   A+ +      +      + Y I  L P   Y+  +     Y ++D  +S 
Sbjct: 9032 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD 9091

Query: 1804 PVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVV 1858
             VVI D       P   + LA T  S+LVSW PP     + ITGY ++  + GSP    V
Sbjct: 9092 KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRV 9151

Query: 1859 PRPRPGVTEATITGLE 1874
               R  +T+  + G+E
Sbjct: 9152 --SRAPITKVGLKGVE 9165



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 171/752 (22%), Positives = 283/752 (37%), Gaps = 116/752 (15%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 9580  TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9639

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 9640  VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9693

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 9694  TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9751

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 9752  ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9804

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 9805  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9864

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 9865  RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 9921

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 9922  IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 9981

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQWTP 1654
             ++ + GL+    Y   V A N +G  +P   T V       ++K   V+P   L A    
Sbjct: 9982  KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV------IEMKDRLVSPDLQLDASVRD 10035

Query: 1655  PNVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1702
               V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   V
Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10095

Query: 1703  YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQ 1755
             Y+L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + 
Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10155

Query: 1756  VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1806
             ++   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+
Sbjct: 10156 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10213

Query: 1807  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1862
              +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V    
Sbjct: 10214 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10273

Query: 1863  PGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                 + T+ GL+ G  Y   V A+    + +P
Sbjct: 10274 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10305



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 258/1144 (22%), Positives = 397/1144 (34%), Gaps = 207/1144 (18%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
             P P ++L+   VT    TI W  P     S +T +   ++    P + G  +  S  T  
Sbjct: 11505 PGPCQNLKVTNVTKENCTISWENPLDNGGSEITNF---IVEYRKPNQKGWSIVASDVTKR 11561

Query: 963   EV-TGLSPGVTYYFKVFA-----VSHGRESKP--LTAQQTTKLDAPTNLQFVNETDSTVL 1014
              +   L     YYF+V A     V    E+K   L      +   P NL   ++  + V 
Sbjct: 11562 LIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVY 11621

Query: 1015  VRWTPPRAQITGYRLTVGLTRR------------GQPRQ--YNVGPSVS------KYPLR 1054
             ++W  P        L+  + RR            G  ++  Y V   V       +   +
Sbjct: 11622 LKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTK 11681

Query: 1055  NLQPASEYT-VSLVAIKGNQESP----KATGVFTT-------LQPGSSIPPY-NTEVTET 1101
             N    S++     V +K + + P    K +GV T        L+ G    P+     T+ 
Sbjct: 11682 NEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD 11741

Query: 1102  TIVITWTPAPRIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVY--TIQVLRD 1158
                   T +PR+  K+  R  S      +   SD G  VV+       +V   T+ VL  
Sbjct: 11742 KDATDLTRSPRV--KIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL-- 11797

Query: 1159  GQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVS---WERSTTPDI--TGYRIT--- 1209
               ++  P+ N K+V   S    +  +   D G   +     E+  T  +  + Y  T   
Sbjct: 11798 --DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLT 11855

Query: 1210  --TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
               TT T   +GN     V A+    T     P  E    +   K DK          P  
Sbjct: 11856 PGTTVTRLIEGNEYIFRVRAENKIGT----GPPTESKPVIAKTKYDK----------PGR 11901

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS---DNAVV 1324
             P P ++  T +  + M V W PP      +    +   K +     + ++ S   +  + 
Sbjct: 11902 PDPPEV--TKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMK 11959

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDS------PTGIDFSDITANSFTVH 1377
             + NLLP  EY   V +  E     P L  R     D       PT     D T +S T+ 
Sbjct: 11960 VQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLG 12019

Query: 1378  WIAP----RATITGYRIRHHPEHFSGRPRED------RVPHSRNSITLTNLTPGTEYVVS 1427
             W  P     A I GY +   P+     P E            R   T+T+L    EY   
Sbjct: 12020 WGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFR 12079

Query: 1428  IVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
             + A N      + IG+ + + +  +  E++      L  S     V VR           
Sbjct: 12080 VCAQN-----QVGIGRPAELKEAIKPKEILEPPEIDLDASM-RKLVIVR----------A 12123

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTIT-------------VYAVTGRGDS------- 1527
               P++ F +   +    ++  K G+D  +              V   + R DS       
Sbjct: 12124 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 12183

Query: 1528  --PASSKPISINYRTEIDKP---SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTP 1578
               PA  K + +N R  +D P   S ++V+DV   S  V W P      S VT Y V    
Sbjct: 12184 VNPAGEKAVFVNVRV-LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKRE 12242

Query: 1579  KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTT 1631
              +      T T    +T   +  L P  EY   V A N  G   P       L    ++ 
Sbjct: 12243 ADRK-TWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE 12301

Query: 1632  IPAPTDLKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
                P  L+ T++T  S +  W PP        +  +T YR    P ++     E ++  D
Sbjct: 12302 PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKD 12358

Query: 1684  SSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----- 1736
              S +VV+GL    KY+  V A      S P  A+GV    E + PP+       T     
Sbjct: 12359 LS-LVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGK 12417

Query: 1737  ----------ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGL 1783
                       +   T  W+  + E +T   +    A+  +   I+   + D   Y++T  
Sbjct: 12418 KLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAE 12477

Query: 1784  QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----AR 1839
                           D  +   VV+DA      P ++  +     SL  SW  P     + 
Sbjct: 12478 NSSG---------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSN 12526

Query: 1840  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1899
             IT YI++ +   S    V        T   +  L PG EY   V A      SEPL   K
Sbjct: 12527 ITNYIVE-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPK 12585

Query: 1900  KTGQ 1903
                Q
Sbjct: 12586 MVAQ 12589



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 117/534 (21%), Positives = 206/534 (38%), Gaps = 63/534 (11%)

Query: 1414 TLTNLTPG-TEYVVSIVALNG-------REESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
            T+T L  G  EY+  + A N          ++P+    +  V   P ++ +       + 
Sbjct: 6652 TVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVS 6711

Query: 1466 ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
            ++W+ P       +  Y I   +          TV     +AT++ +  G +Y+  V A 
Sbjct: 6712 LTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQ 6771

Query: 1522 TGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV 1574
               G    S+    +     I++PS    +  +D   +S+ +KW P      SP+ GY +
Sbjct: 6772 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6831

Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634
                +      +       +    + GL+   +Y+  V A+N +G S P      + I  
Sbjct: 6832 ERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP------SEILG 6885

Query: 1635 PTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PKEKTGPMKE 1677
            P       V PT  LSA     +   PN     V  TGY R   T        +TG   +
Sbjct: 6886 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 6945

Query: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTDA 1735
            +      + +V+S    + + +  +Y LK     +   G   V  +   S P+  +  D 
Sbjct: 6946 MKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDI 7002

Query: 1736 TETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
            T+ ++ ++W    +     +TG+ V+    + +T  +         +T+  L  G +Y  
Sbjct: 7003 TKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLF 7062

Query: 1792 YLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPPR----ARI 1840
             +   N      P  +D        +T  D P N+++   T NS+ ++W PP+    +RI
Sbjct: 7063 KVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRI 7122

Query: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             GYI++    GS        P    T+  +TGLE G  Y   V AL     S+P
Sbjct: 7123 KGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7175



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 249/1231 (20%), Positives = 420/1231 (34%), Gaps = 187/1231 (15%)

Query: 806  SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
            S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 6689 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6748

Query: 861  TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
               S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 6749 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6803

Query: 916  VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
             + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 6804 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6863

Query: 972  TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
             Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 6864 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 6923

Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
             PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 6924 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 6979

Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
            +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 6980 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7034

Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
            +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 7035 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7094

Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
             N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 7095 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7152

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPT---------------------- 1271
              L  G  Y   V  +     S P   T  I AV                          
Sbjct: 7153 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7211

Query: 1272 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
            +L  T  G    ++TW     I   +  +    V  +  V  +    SD          G
Sbjct: 7212 ELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT---------G 7262

Query: 1332 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITG 1387
            T  + +V+          +    K G   P   D +D+T  S  + W  PR    + IT 
Sbjct: 7263 TYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDVTNESCLLTWNPPRDDGGSKITN 7320

Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSIT------LTNLTPGTEYVVSIVALNGR------E 1435
            Y +         R  +  V H  +S         T L P  EY+  + A N        +
Sbjct: 7321 YVVER-------RATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQ 7373

Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPV 1491
             SP+    Q      P  LE    T  ++ ++W  P       +  Y +   +   +  V
Sbjct: 7374 ASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWV 7433

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYRTEIDKP---S 1546
            +   +P   +T  + GL     Y   V A  + G G    S++PI I  +  ID P    
Sbjct: 7434 RCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI--KDPIDPPWPPG 7491

Query: 1547 QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
            +  V DV   S+ + W        + +  Y V    K G         G   T+  + GL
Sbjct: 7492 KPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKTGTDEWVRVAEGVPTTQHLLPGL 7550

Query: 1603 QPTVEYVVSVYAQNPSGESQP-------LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP 1655
                EY   V A N +GES+P       L +  +     P  L+   +T  +   +WT P
Sbjct: 7551 MEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVP 7610

Query: 1656 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
                   +T Y V      + G  + ++     +   V+ L      E S+Y  +    +
Sbjct: 7611 EKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGSLYVFRVAAEN 7664

Query: 1712 RPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1757
               Q   T +E+            PP    V D T+  + + W          I  + ++
Sbjct: 7665 AIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE 7724

Query: 1758 AVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVID 1808
                 G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P        + D
Sbjct: 7725 KKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIED 7783

Query: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP-REVVPRPRP 1863
             ++    P +L         + ++W+PP     + I GY ++    G+     V  RP  
Sbjct: 7784 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7843

Query: 1864 GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             +      G+ P  EY + V A+     SEP
Sbjct: 7844 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEP 7874



 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 265/1308 (20%), Positives = 462/1308 (35%), Gaps = 209/1308 (15%)

Query: 814   PPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
             P D T D     S+ + W  P     + IT Y +    +   S +         +  ++ 
Sbjct: 14379 PTDITKD-----SVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTG 14433

Query: 870   LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWT 928
             L  G +Y   + A  E     P     ETT   ++   PSP D L  +++T   V++ W 
Sbjct: 14434 LSEGCEYFFRVMAENEYGIGEPT----ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWP 14489

Query: 929   PPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHG 983
              P+    S +TGY   VI     G +    +   +     V  L+ G  Y F+V AV+  
Sbjct: 14490 KPKHDGGSKITGY---VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSA 14546

Query: 984   -----RESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
                  RES+P+  ++ T L     L         V+ +         G  + V +   G+
Sbjct: 14547 GRSAPRESRPVIVKEQTMLP---ELDLRGIYQKLVIAK--------AGDNIKVEIPVLGR 14595

Query: 1039  PRQ---YNVGPSVSKYPLR-NLQPASEYTVSLV--AIKGNQESPKAT--------GVFTT 1084
             P+    +  G  + K   R N +  +  T+  +   ++ +      T        G   T
Sbjct: 14596 PKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVIT 14655

Query: 1085  LQ----PGSSIPPYN-TEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSG--- 1136
             +Q    PG    P    EV+   +  +W P    G   GV  S      R+  S +    
Sbjct: 14656 IQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDG---GVPISNYVVEMRQTDSTTWVEL 14712

Query: 1137  -------SIVVSGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEA 1184
                    +   + LT G+EY + ++      +  G      + N       PP    + A
Sbjct: 14713 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14772

Query: 1185  NPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGL 1241
                   +T+SW    +     I GY +     NG    ++ + +    +      L+ G+
Sbjct: 14773 VTKDS-MTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKAL-VPGNIFKSSGLTDGI 14830

Query: 1242  EYNVSVYTV------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---S 1292
              Y   V         K  K S P+    +  + PP      NI   T+ + WA P     
Sbjct: 14831 AYEFRVIAENMAGKSKPSKPSEPM--LALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGG 14888

Query: 1293  IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
               +T+++V    + N   +     +  +N   ++ L     Y   V +       +P   
Sbjct: 14889 FKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSE 14948

Query: 1353  RQ-----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY 1388
                    +  +++P     + F D        +F            T+ W      + G 
Sbjct: 14949 PSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGT 15008

Query: 1389  -RIRHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIG 1442
              ++      FS     +D       + TLT   PG   +++ ++  L+  G  E PL + 
Sbjct: 15009 AKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVT 15068

Query: 1443  QQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPG 1498
             +                T    ++SW  P       + +Y +   ET   +    +T   
Sbjct: 15069 E---------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVA 15109

Query: 1499  SKSTAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDV 1553
             S+   T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +
Sbjct: 15110 SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTI 15169

Query: 1554  QDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
               +S+ V W        S +  Y V    K G    K            + GL    EY 
Sbjct: 15170 TKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYE 15229

Query: 1610  VSVYAQNPSGESQPLVQT----AVTTI---PAPTDLKFTQVTPTSLSAQWTPP----NVQ 1658
               + A+N +G S P   +    A  T+     P + +    + +S+S  W  P      +
Sbjct: 15230 FRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSE 15289

Query: 1659  LTGYRVRVT-PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--Q 1715
             +TGY V +  P+E    +        ++S  ++GL    +Y++ +YA+       PA   
Sbjct: 15290 ITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVP 15349

Query: 1716  GVVTTLENVSPPR-------RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1768
             G     + + PP        R  VT     T+ +    K       +V     +G++  +
Sbjct: 15350 GTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAP--EVKWARDHGESLDK 15407

Query: 1769  RTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLA 1823
              +I+    SYT  I G     D   Y+ T+ +++ S    ++    +D P    +L+   
Sbjct: 15408 ASIE-STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV-LDTPGPPQDLKVKE 15465

Query: 1824  TTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1879
              T  S+ ++W PP     ++I  YI++  +        V       T   +  L+ G  Y
Sbjct: 15466 VTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVAT-NCHKTSWKVDQLQEGCSY 15524

Query: 1880  TIYVIALKN-------------NQKSEPLIGRKKTGQEAL-SQTTISWA-PFQDTSE--- 1921
                V+A                     PL   K T  +   +  ++SW  P  D      
Sbjct: 15525 YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRIL 15584

Query: 1922  -YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 1968
              YI+     G+D+      V    T AT+TGL +G  Y+  V A  ++
Sbjct: 15585 GYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEK 15630



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 281/1308 (21%), Positives = 470/1308 (35%), Gaps = 187/1308 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 15853 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 15912

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 15913 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 15957

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 15958 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16017

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 16018 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16075

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 16076 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16129

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 16130 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16186

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 16187 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16246

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 16247 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16305

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 16306 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16365

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 16366 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16425

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 16426 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16482

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 16483 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16537

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 16538 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16596

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 16597 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16656

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 16657 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16714

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 16715 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16772

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 16773 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16824

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 16825 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 16884

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTTIPAPTDLKF-TQVT 1644
                   + +  L+   EY   ++A+N  G     ES P+V       P P    F T ++
Sbjct: 16885 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 16938

Query: 1645  PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1700
               S+  QW  P       + GY +    +      K        +      L    +YE 
Sbjct: 16939 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 16998

Query: 1701  SVYALKDTLTSRPAQG--VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGF 1754
              VYA       + ++        +   PP            IT+ W          ITG+
Sbjct: 16999 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17058

Query: 1755  QVDAVPANGQTPIQRTIKPDVRS-----YTITGLQPGTDYKIYLYTLN 1797
              V+        P  R +K    +     +T++GL     Y+  +   N
Sbjct: 17059 IVE----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17102



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 251/1294 (19%), Positives = 472/1294 (36%), Gaps = 172/1294 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 21278 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21337

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 21338 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21382

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 21383 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21442

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 21443 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21497

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 21498 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 21557 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21612

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 21613 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21671

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 21672 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21730

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 21731 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21789

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 21790 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21848

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 21849 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 21908

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 21909 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 21967

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 21968 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22026

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 22027 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22086

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 22087 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22143

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 22144 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22199

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 22200 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22251

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 22252 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTT----IP--APTDLKFTQVTPTSLSAQWTPP--- 1655
              +EY   V ++N  G S+PL    +      +P  APT  +   V+  ++S +W  P   
Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22370

Query: 1656  -NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1714
                ++ GY V    +     +KE  +     +  V+GL+   +Y+   YAL     S+ +
Sbjct: 22371 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22430

Query: 1715  QGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPAN-----G 1763
             +    +     V  P R  VTD T +T+++ W          + G+ ++  P +      
Sbjct: 22431 EASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 22490

Query: 1764  QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797
                   TI  D   +T+T L  G  Y+  +   N
Sbjct: 22491 WLKCNYTIVSD-NFFTVTALSEGDTYEFRVLAKN 22523



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 112/526 (21%), Positives = 198/526 (37%), Gaps = 49/526 (9%)

Query: 1412  SITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDVPRDLEVVAATPTSLL 1465
             S  +T L  G EY   I+A+N        E  P++      V D P+  EV   T  S++
Sbjct: 16198 SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMI 16257

Query: 1466  ISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
             + W+ PA      +  Y +   +  G    +       +    ++GL    DY   V A 
Sbjct: 16258 VVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAE 16317

Query: 1522  TGRG---DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV 1574
                G    SP S+   + +   +   P+  +V D+  +S+ + W          + GY V
Sbjct: 16318 NAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIV 16377

Query: 1575  TTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQ 1626
                  + G     T   G ++T + +E L    EY   + A N +G  +        +V+
Sbjct: 16378 EKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVE 16437

Query: 1627  TAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAP 1682
               +       DL+  ++                   + R TP+ K     G +++  +  
Sbjct: 16438 EKLEAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIID 16493

Query: 1683  DSSSVVVSGLMVATKYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
              +SS     L    +Y+   Y L  +++  ++ A   V  L+  SPP   +VT+ T+ ++
Sbjct: 16494 VTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16553

Query: 1741  TISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
             +I+W          I  + V+   A  ++           S+ I  LQ G  Y   +   
Sbjct: 16554 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16613

Query: 1797  NDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYE 1848
             N+     P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +
Sbjct: 16614 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQ 16673

Query: 1849  KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
                S       R +    +A IT L  G EY   V+A+    +S+P
Sbjct: 16674 AKHSEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDP 16717



 Score = 78.6 bits (192), Expect = 6e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19571 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19630

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19631 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19682

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19683 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19734

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19735 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19792

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19793 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19852

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 19853 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 19909

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 19910 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 19963

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 19964 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20014

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20015 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20134

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20135 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20193

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20249

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 20250 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20294



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 278/1381 (20%), Positives = 487/1381 (35%), Gaps = 191/1381 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 10774 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10830

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 10831 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 10889

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 10890 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 10949

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 10950 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11007

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 11008 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11062

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 11063 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11120

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 11121 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11180

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 11181 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11240

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 11241 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11300

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 11301 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11359

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 11360 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11419

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 11420 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11477

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 11478 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11528

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 11529 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11586

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 11587 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11646

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 11647 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11704

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 11705 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11754

Query: 1599  IEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPT 1646
             I+    + ++ ++           V A N +G         V   P P  +LK   V+  
Sbjct: 11755 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 11814

Query: 1647  SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
               +  W PP     G  ++    EK    K +  +  S++V+  G  V    E + Y  +
Sbjct: 11815 RCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFR 11872

Query: 1707  DTLTSRPAQGVVTTLENV---------SPPRRARVTDATETTITISWRTKT----ETITG 1753
                 ++   G  T  + V           P    VT  ++  +T+ W        ++ITG
Sbjct: 11873 VRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITG 11932

Query: 1754  FQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND------NARSSPV 1805
             + ++    +     P+ ++  P+ R   +  L P  +Y+  +   N+      +  S PV
Sbjct: 11933 YFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991

Query: 1806  VI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEK--PGSPPREVV 1858
             V  D       P+N R + TT +S+ + W  P     A I GY+++       + P E  
Sbjct: 11992 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12051

Query: 1859  PRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWA 1914
              R          E T+T L+   EY   V A     +++  IGR    +EA+    I   
Sbjct: 12052 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCA-----QNQVGIGRPAELKEAIKPKEILEP 12106

Query: 1915  P 1915
             P
Sbjct: 12107 P 12107



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 210/1000 (21%), Positives = 366/1000 (36%), Gaps = 157/1000 (15%)

Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
            P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6654

Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
            GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 6655 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6712

Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
            +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 6713 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6771

Query: 1251 KDDKESVPISDTIIPAVP-------PPTDLRFTNIGPDTMRVTWAPP----PSIDLTNFL 1299
                   P + T    V        PP +L  ++    ++++ W PP     S  L   +
Sbjct: 6772 NRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYII 6831

Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
             R    K+      + + P +    +T L  G +Y+  VS+  +   S P         D
Sbjct: 6832 ERCEEGKDNWIRCNMKLVP-ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 6890

Query: 1360 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1419
                    D++A    +  I P           +P   +     D+V  + + + +  L+
Sbjct: 6891 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLS 6950

Query: 1420 PGTEYVVSIVALNGREESPL-LIGQQSTVS-----------DVPRDLEVVAATPTSLLIS 1467
               E V+S    + +    L L  +  T+S             P++L+    T  S+ ++
Sbjct: 6951 AYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT 7010

Query: 1468 WDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA---------------TISGLKPGV 1512
            W+ P            +  G SP+  + V   + +                T+  L  G 
Sbjct: 7011 WEPP------------DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGK 7058

Query: 1513 DYTITVYAVT--GRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP----S 1565
            +Y   V A    G G+     +P++++    + D P  ++  D   NSI + W P     
Sbjct: 7059 EYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDG 7118

Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
             S + GY V   P+   G  K    G    +T+M + GL+    Y   V A N  G S+P
Sbjct: 7119 GSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 7175

Query: 1624 LVQT----AVTTIPAP---------TDLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPK 1669
               T    AV T  AP           L     T   L A  T  P  ++T  +  +  K
Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235

Query: 1670 EKTGPMKEINL--APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV--TTLENVS 1725
            +     K I +   P  S+V +   + + + +   Y ++       A  VV    L+   
Sbjct: 7236 QD----KRITIENVPKKSTVTI---VDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG 7288

Query: 1726 PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT--PIQRTIKPDVRSYT 1779
            PP    +TD T  +  ++W    +     IT + V+    + +    +  T+K    ++ 
Sbjct: 7289 PPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD--TNFK 7346

Query: 1780 ITGLQPGTDYKI-----YLYTLNDNARSSPVVIDASTAID---APSNLRFLATTPNSLLV 1831
             T L P  +Y        +Y + +  ++SP  I A    D    P+ L     T +++ +
Sbjct: 7347 ATKLIPNKEYIFRVAAENMYGVGEPVQASP--ITAKYQFDPPGPPTRLEPSDITKDAVTL 7404

Query: 1832 SWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL- 1886
            +W  P     + ITGY ++   P +       +     T   + GL    +Y   V+A  
Sbjct: 7405 TWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAEN 7464

Query: 1887 -----KNNQKSEPLI-----------GRKKTGQEALSQTTISWA-PFQD----TSEYIIS 1925
                 K ++ +EP++           G+        +   ++W  P  D       Y+I 
Sbjct: 7465 LAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIE 7524

Query: 1926 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
                GTDE  ++      +T   L GL  G  Y+  V A+
Sbjct: 7525 MLKTGTDEW-VRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7563



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 316/1566 (20%), Positives = 536/1566 (34%), Gaps = 237/1566 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-Y 666
             P  V +T+T     S  ++W+ P       I  YI+    K  +G W +      + + Y
Sbjct: 21760 PTVVKVTDTSKTTVS--LEWSKPVFDGGMEIIGYIIEMC-KADLGDWHKVNAEACVKTRY 21816

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
             T+  L+ G  Y+ ++ +I   G  +         S     T   V   T P   + A  +
Sbjct: 21817 TVTDLQAGEEYKFRVSAINGAGKGD---------SCEVTGTIKAVDRLTAPELDIDANFK 21867

Query: 727   SVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
                 + A + +  +++     + T    + +  LS   D     D  ST T  N      
Sbjct: 21868 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI-HTTDSFSTLTVENCNRNDA 21926

Query: 783   GRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
             G KY + V   S  G +S+  +      P  P   T   V   S  + W  P     A I
Sbjct: 21927 G-KYTLTVENNS--GSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARI 21983

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
               Y +    +   S   ++   T     ++DL  GV Y   + AV E     P  + +  
Sbjct: 21984 HHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22043

Query: 899   TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN----LPGEH 950
               T +      PR L  V+ +     + W  P+    S +TGY +++        +   H
Sbjct: 22044 VATEQP---APPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH 22100

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETD 1010
              ++L  +     E T       Y F+V A +    S+P  A  +  +  P          
Sbjct: 22101 TKQLTFTVERLVEKT------EYEFRVKAKNDAGYSEPREAFSSVIIKEPQ--------- 22145

Query: 1011  STVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV------GPSVSKYPLRNLQPASEYTV 1064
                      P A +TG    +   + G P   +V       P V+ + L  ++      V
Sbjct: 22146 -------IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVT-WKLEEMRLKETDRV 22197

Query: 1065  SLVAIKGN-----QESPKATG--VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--- 1114
             S+   K       ++S +      F TL+  + +  ++      T+V+   P P  G   
Sbjct: 22198 SITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSV-----TVVVIGRPGPVTGPIE 22252

Query: 1115  ----------FKLGVRPSQGGEAPREVTS------DSGS--------------IVVSGLT 1144
                          G  P  GG    E+T+      +SG+              I V+ LT
Sbjct: 22253 VSSVSAESCVLSWG-EPKDGGGT--EITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLT 22309

Query: 1145  PGVEYVYTIQVL-RDGQER---DAPIV--NKVVTPLSP--PTNLHLEANPDTGVLTVSWE 1196
               +EY + +    R G  +    API+  +  V P +P  P   H+ AN     +++ WE
Sbjct: 22310 KYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSAN----AMSIRWE 22365

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSL----EEVVHADQSSCTFDNLSPGLEYNVSVYTV-- 1250
                     G +I       ++ N++    E  V   + +     L  GLEY    Y +  
Sbjct: 22366 EPYHDG--GSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423

Query: 1251  ----KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1303
                 K  + S PI       V  P     T++   T+ + W+ P       +  +++   
Sbjct: 22424 AGVSKASEASRPIMAQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERK 22481

Query: 1304  PVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PLRGR 1353
             PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+  R
Sbjct: 22482 PVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR 22541

Query: 1354  Q-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRPRED 1404
                   K  LD+    D   I A S  V   A    P   I   +     +       + 
Sbjct: 22542 DEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY 22601

Query: 1405  RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRD---LEVVAATP 1461
                 +   I   + +   +Y +++   +G +   +++     V D P     L V   T 
Sbjct: 22602 TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSRVTQ 22657

Query: 1462  TSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGVDYT 1515
                 ++W  P       + +Y +   ET   S +    V G   T +  ++ L    +Y 
Sbjct: 22658 EKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNNEYI 22714

Query: 1516  ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQM-QVTDVQDNSISVKWLPSSSP----V 1569
               V AV   G   P  S+PI       I  P  + +        I ++W    S     +
Sbjct: 22715 FRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEI 22774

Query: 1570  TGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             + Y V    K     T+  K      T + +  L    +Y   V A N +G S+P   + 
Sbjct: 22775 SNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 22834

Query: 1629  VT-------TIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMK- 1676
                      T   P+  +    T  S+S  WT P       + GY + +  K+     + 
Sbjct: 22835 FISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRV 22894

Query: 1677  EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPRRARVTD 1734
               N    ++   V  L +  KY   V A+     S  ++ +  +  +E +  P    + D
Sbjct: 22895 HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD-LELAD 22953

Query: 1735  ATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTIKPDVRSYTITGLQPGTDY 1789
               + T+TI        +        P       G     R I     SY++  +     Y
Sbjct: 22954 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 23013

Query: 1790  KIYLYTL---NDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPR----ARIT 1841
                 YT+   N + + S  V+        P  +++    + +S+ ++W+ P     A + 
Sbjct: 23014 DAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVN 23073

Query: 1842  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP------- 1894
              YI++  +      + V   +   T   I+GL  GT Y   V+        EP       
Sbjct: 23074 NYIVEKREAAMRAFKTVTT-KCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAV 23132

Query: 1895  ------LIGRKKTGQEALSQT-TISWA-PFQDTSE----YIISCHPVGTDEEPLQFRVPG 1942
                   L+  K    +    T T++W  P  D       Y++     GT+       +  
Sbjct: 23133 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23192

Query: 1943  TSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTV 2002
             T    T+T L  G  Y   + A  ++   + RE V  V  +V +    PT D    P   
Sbjct: 23193 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAV--TVQDLRVLPTIDLSTMPQKT 23250

Query: 2003  SHYAVG 2008
              H   G
Sbjct: 23251 IHVPAG 23256



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 266/1357 (19%), Positives = 484/1357 (35%), Gaps = 178/1357 (13%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20084

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 20085 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20144

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 20145 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20202

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 20203 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20259

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 20260 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20317

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 20318 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20377

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 20378 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20433

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 20434 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20493

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 20494 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20553

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 20554 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20609

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 20610 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20667

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 20668 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20726

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 20727 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20785

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 20786 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20845

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 20846 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 20962

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 20963 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21019

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP-TSLSAQW 1652
             T E+ +  L+        V+A+N  G S P+      TI  P  +K   +TP   LS   
Sbjct: 21020 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV------TI-GPITVKELIITPEVDLS--- 21069

Query: 1653  TPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV-YALKDT 1708
               P  Q+T   G+ V +    K  P   I+   D   +  S  +  +K E  +  ++K+ 
Sbjct: 21070 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21129

Query: 1709  LTSRPAQ------------GVVTTLENVSPPRR----ARVTDATETTITISWRTKTET-- 1750
                   +             V  T+  + PP +     R  +    ++ +SW    +   
Sbjct: 21130 KKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21189

Query: 1751  --ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
               IT + ++      QT  +       R ++ +  L    +Y+  +   N    S P+V 
Sbjct: 21190 GEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 21248

Query: 1808  DASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREV 1857
                 A         P        T + + ++W  P     + +TG+ ++ ++  S   + 
Sbjct: 21249 SIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQK 21308

Query: 1858  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
             V        E   TGL  G +Y   V A  +   S P
Sbjct: 21309 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 21345



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 8995 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9052

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9053 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9105

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9106 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9159

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9160 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9219

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9220 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9279

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9280 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9311



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24229 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24283

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24284 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24343

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24344 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24403

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24404 CENLGGESEWSEISEPI--TPKSD 24425



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24612 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24669

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24670 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24729

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24730 EVDETREVSMT 24740



 Score = 35.8 bits (81), Expect = 0.47
 Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 12/134 (8%)

Query: 1534  ISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSS----SPVTGYRVTTTPKNGPGPTKTK 1588
             + +  + + DKP+   V + +  NS  + W P +    S +T Y V           +  
Sbjct: 24218 LDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLV 24277

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL-------KFT 1641
             ++    T   I  L     Y   V AQN  G S PL  ++V  I +P +          T
Sbjct: 24278 SSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTIT 24337

Query: 1642  QVTPTSLSAQWTPP 1655
              VT  S    W PP
Sbjct: 24338 AVTKDSCVVAWKPP 24351


>gi|222352127 sidekick 2 [Homo sapiens]
          Length = 2172

 Score =  148 bits (373), Expect = 7e-35
 Identities = 273/1273 (21%), Positives = 467/1273 (36%), Gaps = 170/1273 (13%)

Query: 772  ATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTS 826
            ATSV +  L+P R Y   +  +++ G+      T + + P+ PP      V      + S
Sbjct: 647  ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQS 706

Query: 827  IVVRWSRP-----QAPITGYRIVY--SPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
            I+++W  P        + GY I Y  +    G   +       N++ L DL     Y I 
Sbjct: 707  IMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIE 766

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV----- 934
            + A   N     V   + T  T +      P ++         +   W  P         
Sbjct: 767  VAAY--NSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824

Query: 935  TGYRVDVIPVNLPGEHGQRLPISRNTFAE------VTGLSPGVTYYFKVFAVS---HGRE 985
             GY+  +I      E    +  +R  F +      V+GL     Y+  V   +    G  
Sbjct: 825  QGYK--LIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPR 882

Query: 986  SKPLTAQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPRQ 1041
            S P   +    +  P  +L F    D+++ V W  P  +   +TGYR++     R   R 
Sbjct: 883  STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRV 942

Query: 1042 YNVGPSVS-KYPLRNLQPASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
             +  P+V+ +Y +  L   + YT+ + A+    Q    A+ + + + P    PP N  ++
Sbjct: 943  THYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGIS 1002

Query: 1100 E----------------TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVS 1141
                              T +  W    ++G    V   +      ++++  D+ S+ V 
Sbjct: 1003 NIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV---VGEGEEWLLIHQLSNEPDARSMEVP 1059

Query: 1142 GLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW- 1195
             L P   Y + + QV   G    +    K+ T  +P    P N+ L    +T  L + W 
Sbjct: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS-LWLRWM 1118

Query: 1196 -----ERSTTPDITGYRITTTPTNGQQGNSLEEVVH-ADQSSCTFDNLSPGLEYNVSVYT 1249
                 E +  P+  GY+I  + ++G  G +L  VV    +   T ++L    EY V V  
Sbjct: 1119 PLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQA 1177

Query: 1250 VKDDKESVPISDTII----PAVPP--PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
              +   S P S T++     +VP   PT++        +M V W+  P  D    ++ Y 
Sbjct: 1178 F-NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYK 1236

Query: 1304 PVKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-----LRGR 1353
             +  E+D        L    S  +  LT L     Y V V +     + +P     L   
Sbjct: 1237 VMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT 1296

Query: 1354 QKTGLDSPTGIDFSDITANSFTVHW---IAPRATITGYRIRHHPEHFSGRPREDRV-PHS 1409
                   P GI F ++   S  + W    AP   I  Y+I H     +       V   S
Sbjct: 1297 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPS 1356

Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA---ATPT 1462
                T T L P + Y+  I A      G     L++  +      P    +V        
Sbjct: 1357 ARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416

Query: 1463 SLLISWDAPA---VTVRYYRITYGE-TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            S+L+SW+  +     VRYY I   E   G   +   +V  + S+  +  LKP   Y   V
Sbjct: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRV 1476

Query: 1519 YAVTGRGDSPAS--SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP-----VTG 1571
             A    GDS  S  S+ ++       + P+ + VT     S+ ++W P +       + G
Sbjct: 1477 KATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLG 1536

Query: 1572 YRV-------------TTTPKNGPGPTKTKTAG---------PDQTEMTIEGLQPTVEYV 1609
            +R+             T    N PG T  +            P  T+  ++ L     Y 
Sbjct: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYE 1596

Query: 1610 V--SVY---AQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPP-----NVQL 1659
            +  SVY    + PS   Q +         AP ++     T T L   W PP     N  +
Sbjct: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656

Query: 1660 TGYRVRVTPKEK---TGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK---DTLTSRP 1713
             GY++     ++   T  +K + LA   +SV +  L   T Y VSV A     D   S P
Sbjct: 1657 QGYKIYFWEAQRGNLTERVKTLFLA--ENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTP 1714

Query: 1714 AQGVVTTLENVSPPRRARVTDATETTITISWRT---KTETITGFQVDAVPANGQTPIQRT 1770
             QG  T     S P   + ++ T T++ +SW         + G+++   P +    + + 
Sbjct: 1715 TQG-QTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKI 1773

Query: 1771 IKPDVRSYT-----ITGLQPGTDYKIYL----YTLNDNARSSPVVIDASTAIDAPSNLRF 1821
            +  DV+  +     +  L  G  Y+  +    +T      ++ V          P  +  
Sbjct: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN-VTTGPGEGAPGPPGVPI 1832

Query: 1822 LATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA---TITGLEP 1875
            +    +++ + W    P +  IT Y+I+         +++ +  P    +   ++  L+P
Sbjct: 1833 IVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892

Query: 1876 GTEYTIYVIALKN 1888
            G  Y   VIA+ +
Sbjct: 1893 GVSYDFRVIAVND 1905



 Score =  142 bits (359), Expect = 3e-33
 Identities = 293/1374 (21%), Positives = 509/1374 (37%), Gaps = 189/1374 (13%)

Query: 594  IGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQ-------------WNAPQP--SHI 638
            IG + C+ +    + S    + + + P  P  HP+              W  P    S +
Sbjct: 564  IGTYTCRVISAGGNDSRSAHLRVRQLPHAPE-HPVATLSTVERRAINLTWTKPFDGNSPL 622

Query: 639  SKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFT 698
             +YIL     N+      A++     S T+KGL P   Y+ +L ++   G  +   F   
Sbjct: 623  IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ---FSKD 679

Query: 699  TTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT-----VSGFRVE 753
            T   S P         T P   ++A+       T  S ++ W    ++     + G+ + 
Sbjct: 680  TERVSLPEEP-----PTAPPQNVIASGR-----TNQSIMIQWQPPPESHQNGILKGYIIR 729

Query: 754  YELSEEGDEPQYLDL-PSTATSVNIPDLLPGRKYIVNVYQISEDG---EQSLILSTSQTT 809
            Y L+      Q+ ++  +   ++ + DL+    Y + V   +  G     S +   +   
Sbjct: 730  YCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQG 789

Query: 810  APDAPP-DPTVDQVDDTSIVVRWSRPQAPI-----TGYRIV-YSPSVEGSSTEL----NL 858
             P  PP +   +  + T+I   W+ P          GY+++ + P  E   T +    N 
Sbjct: 790  VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNF 849

Query: 859  PETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTPRSDTVPSP-RDLQ 914
             ++ +   +S L+   +Y  ++       +   STP +++         + VP P   L 
Sbjct: 850  QDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH-------EDVPGPVGHLS 902

Query: 915  FVEVTDVKVTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
            F E+ D  + + W  P      +TGYR+     N           +      VTGL+   
Sbjct: 903  FSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT 962

Query: 972  TYYFKVFAVSHGRESKPLTAQQTTKL-----DAPTNLQFVNETDSTVLVRWTP---PRAQ 1023
            TY  +V A++   + +   +  ++ +       PTNL   N    +V +++ P    +  
Sbjct: 963  TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022

Query: 1024 ITGY--RLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVSL--VAIKGNQES 1075
            I+ +     VG+   G+      Q +  P      + +L P + Y+  +  V I G    
Sbjct: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAPR---------IGFKLGVRPSQ 1123
             + +    TLQ    + P N  +   +ET++ + W P P          +G+K+    S 
Sbjct: 1083 SQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSD 1142

Query: 1124 G-GEAPREVTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV------TPL 1174
            G G+    V  D       +  L    E  Y +QV         P    VV       P 
Sbjct: 1143 GHGKTLSHVVQDRVERDYTIEDLEEWTE--YRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200

Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
            S PTN+   A   + +L V W      D    + GY++     +         V      
Sbjct: 1201 SGPTNVSALATTSSSML-VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259

Query: 1231 SCTFDNLSPGLEYNVSVYT---VKDDKES-VPISDTIIPAVP-PPTDLRFTNIGPDTMRV 1285
            S     L   + Y V V     + D   S  PI +  +  VP PP  + F  +   ++R+
Sbjct: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL 1319

Query: 1286 TWAPP--PSIDLTNFLVRYSPVKNEEDVAELSI-SPSDNAVVLTNLLPGTEYVVSVSSVY 1342
             W PP  P+  +  + + +       + A + + +PS      T L P + Y+  +++  
Sbjct: 1320 IWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379

Query: 1343 -----EQHESTPLRGRQKTGLDSPTG--IDFSDITANSFTVHWIAPR---ATITGYRIRH 1392
                 E  E+  +   ++     P+   +   D+ A S  + W       + +  Y I+ 
Sbjct: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQT 1439

Query: 1393 HPEHFSGR--PREDRVPHSRNSITLTNLTPGTEYVVSIVALNG------REESPLLIGQQ 1444
              E  SGR       V H+ +S  +  L P T Y   + A N        EES  L   Q
Sbjct: 1440 R-ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ 1498

Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPA----------VTVRYYRITY----GET--GGN 1488
            +   + P  L V   T TS+LI W  PA            +RY  + Y    G T  G N
Sbjct: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558

Query: 1489 SP------------VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS-SKPIS 1535
            +P            ++  + P S +   +  L     Y I +      G+ P+S  + + 
Sbjct: 1559 NPGATWAELTSMYSMRNLSRP-SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617

Query: 1536 INYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRV-TTTPKNGPGPTKTKT 1589
            +        P  + V       + V W P      +  + GY++     + G    + KT
Sbjct: 1618 VGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKT 1677

Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLV-QTAVTTIPAPTDLKFTQVTP 1645
                +  + ++ L     Y+VSV A N +G+   S P   QT      AP+ +KF+++T 
Sbjct: 1678 LFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737

Query: 1646 TSLSAQWTP---PNVQLTGYRVRVTP-KEKTGPMKEINLAPDSSS---VVVSGLMVATKY 1698
            TS++  W     PN  L GYR+   P     G  K + +    +S   + V  L     Y
Sbjct: 1738 TSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTY 1797

Query: 1699 EVSVYALKDTLTSRPAQGVVTTLENVSP-PRRARVTDATETTITISWRTKTE---TITGF 1754
               + A   T        V T     +P P    +     + I I W +       IT +
Sbjct: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRY 1857

Query: 1755 QVDAVPAN-GQTPIQ-RTIKPDVRSYTITG--LQPGTDYKIYLYTLNDNARSSP 1804
             ++A P++ G   I  + I  +V SYT +   L+PG  Y   +  +ND    +P
Sbjct: 1858 VIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911



 Score =  127 bits (320), Expect = 9e-29
 Identities = 233/1060 (21%), Positives = 401/1060 (37%), Gaps = 152/1060 (14%)

Query: 600  QPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH--ISKYILRWRPKNSVGRWKEA 657
            Q ++T+    GPV   ++ +     S  + W  P   +  ++ Y + W   N        
Sbjct: 886  QLVRTHEDVPGPVG-HLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTH 944

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
             +P     Y + GL     Y  ++ ++   G  +V+              ++T++    P
Sbjct: 945  YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS--------------ASTISSGVPP 990

Query: 718  FSPLVATSESVTEITASSFVVSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPST--- 771
              P   T+  ++ I   S  + +    D   ++S + VE ++   G+  ++L +      
Sbjct: 991  ELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 1050

Query: 772  --ATSVNIPDLLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD 824
              A S+ +PDL P   Y      VN+   S   + S  + T Q     AP + ++    +
Sbjct: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110

Query: 825  TSIVVRW---------SRPQAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPG 873
            TS+ +RW           P++   GY+I YS S     T  ++ +       T+ DL+  
Sbjct: 1111 TSLWLRWMPLPEMEYNGNPES--VGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEW 1168

Query: 874  VQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEVTDVKVTIMWTPPE 931
             +Y + + A             Q   G  R ++VPS  P ++  +  T   + + W+   
Sbjct: 1169 TEYRVQVQAFNAIGSGP---WSQTVVGRTR-ESVPSSGPTNVSALATTSSSMLVRWSEVP 1224

Query: 932  SA-----VTGYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFA---VSH 982
             A     V GY+V     +   +    L    ++  A++TGL   V Y  +V A   +  
Sbjct: 1225 EADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGD 1284

Query: 983  GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPRAQ---ITGYRLT--VGL 1033
            G  S P   ++T  LD     P  + F     ++V + W PP A    I  Y++T  +  
Sbjct: 1285 GSPSHPPILERT--LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342

Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTL----QP 1087
            T         + PS  +Y    L+P S Y   + A   KG  E+ +A  V T      QP
Sbjct: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402

Query: 1088 GSSIPPYNTEVTETTIVITWTP-----APRIGFKLGVRPSQGGE---APREVTSDSGSIV 1139
             S       +V   +++++W P     +P   + +  R    G        V+ ++ S +
Sbjct: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462

Query: 1140 VSGLTPGVEYVYTIQVLRD-----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
            V  L P   Y + ++   D       E    +      P   PT L +  +  T VL + 
Sbjct: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL-IR 1521

Query: 1195 WERSTTPDITG--------YR--------------ITTTPTNGQQGNSLEEVVHADQSSC 1232
            W+      I G        YR              I        +  S+  + +  + S 
Sbjct: 1522 WQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSL 1581

Query: 1233 T---FDNLSPGLEYNV--SVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMR 1284
            T    DNL+    Y +  SVY    +  S P  +  +    P   P ++         + 
Sbjct: 1582 TQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLD 1641

Query: 1285 VTWAPPP----SIDLTNFLVRYSPVKN---EEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
            VTW PPP    + D+  + + +   +     E V  L ++  +N+V L NL   T Y+VS
Sbjct: 1642 VTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA--ENSVKLKNLTGYTAYMVS 1699

Query: 1338 VSSVYEQHE---STPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR---ATITGYRI 1390
            V++     +   STP +G+ Q+    +P+ + FS++T  S  V W AP+     + GYR+
Sbjct: 1700 VAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRL 1759

Query: 1391 RHHP-EHFSGRPREDRVPHSRNS---ITLTNLTPGTEYVVSIVALN---GREESPLLIGQ 1443
             + P     G  +   V    NS   + + +L  G  Y   I A     G E    +   
Sbjct: 1760 VYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTG 1819

Query: 1444 QSTVSDVPRDLEVVAATPTSLLISWDA----PAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
                +  P  + ++    +++ I W +         RY         G   +    +P  
Sbjct: 1820 PGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKE 1879

Query: 1500 KSTATISG--LKPGVDYTITVYAVT----GRGDSPASSKP 1533
             S+ T S   LKPGV Y   V AV     G   SP+ S P
Sbjct: 1880 VSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVP 1919



 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 129/545 (23%), Positives = 219/545 (40%), Gaps = 66/545 (12%)

Query: 1413 ITLTNLTPGTEYVVSIVALNGREESP--LLIGQQSTVSDVPRDLEVVAATPTSLL--ISW 1468
            I+ T+++    Y        G +E+   L++  ++ ++  P+D  V+  T  S++  ++ 
Sbjct: 462  ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521

Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
            D P VT+RY     G T G        +  + S   IS    G   T T   ++  G+  
Sbjct: 522  D-PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH-ISQTWSGDIGTYTCRVISAGGNDS 579

Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTPKNGPGPT 1585
             S+  + +       +     ++ V+  +I++ W      +SP+  Y +  +  N P   
Sbjct: 580  RSAH-LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTV 638

Query: 1586 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIP------APTDLK 1639
               +  P  T +T++GL P   Y   + A N  G+ Q    T   ++P       P ++ 
Sbjct: 639  LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698

Query: 1640 FTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKEKTGPMKEINLA-PDSSSVVVSGLM 1693
             +  T  S+  QW PP     N  L GY +R          +  N+   D +++++  L+
Sbjct: 699  ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758

Query: 1694 VATKYEVSVYALKDT--------LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745
            + T YE+ V A            +T    QGV T      PP          TTI  +W 
Sbjct: 759  IWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTV-----PPGNVHAEATNSTTIRFTWN 813

Query: 1746 TKTETI-----TGFQVDA-VPANGQTPIQRTIKPDVRSYT----ITGLQPGTDY---KIY 1792
              +         G+++ A  P   +     T +P+ +       ++GL+  T+Y    + 
Sbjct: 814  APSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLC 873

Query: 1793 LYTLNDNARSSPVVIDASTAIDAP-SNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYE 1848
              T  D  RS+P ++     +  P  +L F      SL VSWQ P  +   +TGY I +E
Sbjct: 874  FTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWE 933

Query: 1849 KPGSPPREVVPRPRPGVT-EATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALS 1907
            +       V     P VT E  +TGL   T YTI V A+ +             GQ  +S
Sbjct: 934  EYNRTNTRVT-HYLPNVTLEYRVTGLTALTTYTIEVAAMTSK------------GQGQVS 980

Query: 1908 QTTIS 1912
             +TIS
Sbjct: 981  ASTIS 985


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score =  146 bits (368), Expect = 2e-34
 Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)

Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
           E  V +   GN++GE C  PF +NG+ + SCT  GR DG LWCSTT N+E+D KY FC  
Sbjct: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226

Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
             +   T GGN+ G  C FPF +   +Y  CT+EGR D  +WCGTT++YD D+K+GFCP 
Sbjct: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284

Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
            A   +   +EG         +G++++          CT  G   G+  C   +   D
Sbjct: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333



 Score =  145 bits (365), Expect = 6e-34
 Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)

Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
           Y  C TD+G   S G  W  T  N +      G    C   A+  T GGN+ G+PC  PF
Sbjct: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245

Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
            + G ++ SCTTEGR DG+ WC TT +Y++D+KY FC +    + T GGNS GA C FPF
Sbjct: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303

Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
            +  + Y  CTS GR D   WC TT NYD D+K+GFCP        +AAHE
Sbjct: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score =  146 bits (368), Expect = 2e-34
 Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)

Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
           E  V +   GN++GE C  PF +NG+ + SCT  GR DG LWCSTT N+E+D KY FC  
Sbjct: 217 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 276

Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
             +   T GGN+ G  C FPF +   +Y  CT+EGR D  +WCGTT++YD D+K+GFCP 
Sbjct: 277 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 334

Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
            A   +   +EG         +G++++          CT  G   G+  C   +   D
Sbjct: 335 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 383



 Score =  145 bits (365), Expect = 6e-34
 Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)

Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
           Y  C TD+G   S G  W  T  N +      G    C   A+  T GGN+ G+PC  PF
Sbjct: 244 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 295

Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
            + G ++ SCTTEGR DG+ WC TT +Y++D+KY FC +    + T GGNS GA C FPF
Sbjct: 296 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 353

Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
            +  + Y  CTS GR D   WC TT NYD D+K+GFCP        +AAHE
Sbjct: 354 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 404


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
            precursor [Homo sapiens]
          Length = 1912

 Score =  145 bits (367), Expect = 3e-34
 Identities = 158/671 (23%), Positives = 270/671 (40%), Gaps = 79/671 (11%)

Query: 1367 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1424
            ++ TA S T+ W +     ++ Y I+H P++     +E D V  +R S+    L+P ++Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 389

Query: 1425 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1476
               +VA+N    G    P+L    +   S  PRD++    + T++L+ W   + P   ++
Sbjct: 390  EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 449

Query: 1477 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
             YR+ Y    T   +   +  V  S+ T TI  L P   Y++ V A T  GD P SS   
Sbjct: 450  GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
             I       +P   +     + SI + W  P S  +  Y +    K+G    + +     
Sbjct: 509  VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 566

Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA-----PTDLKFTQVTPTSL 1648
             T   ++GL+P   Y   + A++P G      + +  T+ +     P D+  T  + TS+
Sbjct: 567  GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 626

Query: 1649 SAQWTPPNVQ-----LTGYRVRVT--PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1701
               W PP V+     +T Y ++ T    E   P + + +  D++  ++  L   T+Y ++
Sbjct: 627  LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686

Query: 1702 VYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET-----ITG 1753
            V A  D      +  V + T E+V   PPR+  V     T++ +SWR+         I G
Sbjct: 687  VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746

Query: 1754 FQVDAVPANGQTPIQRTIKPDV--------------RSYTITGLQPGTDYKIYL---YTL 1796
            +QV  V      P  + +  DV                  I+GLQP T Y + +    T 
Sbjct: 747  YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806

Query: 1797 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP---RARITGYIIKYEKPGSP 1853
             D ARS P ++  + A+     L    T  N+ L+ W PP      + GY +K+ +    
Sbjct: 807  GDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDME 866

Query: 1854 PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQE--------- 1904
            P   +          T T +  G  Y   + A       E ++      +E         
Sbjct: 867  PLTTLEFSEK-EDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNL 925

Query: 1905 -----ALSQTTISWAP------FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLT 1953
                   +   +SW P          ++Y +    +     P++  +    T+ TLTGL 
Sbjct: 926  HSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLK 985

Query: 1954 RGATYNIIVEA 1964
               TY++ V A
Sbjct: 986  PDTTYDVKVRA 996



 Score =  138 bits (348), Expect = 5e-32
 Identities = 227/1017 (22%), Positives = 392/1017 (38%), Gaps = 154/1017 (15%)

Query: 752  VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
            ++ E SEE D+ +Y  + + +         P   Y+  + ++     +  I  T+    P
Sbjct: 192  LQIEQSEESDQGKYECVATNSAGTRYS--APANLYVRELREVRRVPPRFSIPPTNHEIMP 249

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
                + T   V      V+W                  E  + E ++P   N + L+D++
Sbjct: 250  GGSVNITCVAVGSPMPYVKWML--------------GAEDLTPEDDMPIGRNVLELNDVR 295

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPP 930
                Y            ST  VI+     T ++  +P P     V E T   +T+ W   
Sbjct: 296  QSANYTCVAM-------STLGVIEAIAQITVKA--LPKPPGTPVVTESTATSITLTWDSG 346

Query: 931  ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESK 987
                  Y +         E  + +     T   V GLSP   Y F+V AV++   G  S+
Sbjct: 347  NPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSE 406

Query: 988  PLTAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR---AQITGYRL--TVGLTRR-GQP 1039
            P+  Q + +    AP ++Q    + +T+LV+W  P     QI GYR+  T+  T+     
Sbjct: 407  PVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNW 466

Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
             ++NV  S     + NL P   Y+V ++A     + P ++ +    Q G    P N +  
Sbjct: 467  MKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAE 525

Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
              +ET+I+++WTP PR      ++L  +  + GE  R       S  + GL P   Y + 
Sbjct: 526  PESETSILLSWTP-PRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFR 584

Query: 1153 IQVLRDGQERDAPIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD----I 1203
            +   R  Q   A             P +PP ++   +   T +L VSW+          I
Sbjct: 585  LAA-RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL-VSWQPPPVEKQNGII 642

Query: 1204 TGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPI 1259
            T Y I  T  +G+     E + + +D +    + L    EY ++V    D     ES+ +
Sbjct: 643  TEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSV 702

Query: 1260 SDTIIPAVP--PPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEEDVAE 1313
                   VP  PP  +    +   +++V+W +P P+     +  + V Y  ++N E   +
Sbjct: 703  LIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQ 762

Query: 1314 LSISP-------------SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS 1360
              +               +++ ++++ L P T Y ++V++   + +      R K  L S
Sbjct: 763  PMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGA----RSKPKLVS 818

Query: 1361 PTG-------IDFSDITANSFTVHWIAPRAT---ITGYRIRHHPEHFSGRPREDRVP--- 1407
             TG       +  +    N+  + W  P  T   + GYR++          R+D  P   
Sbjct: 819  TTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG--------RKDMEPLTT 870

Query: 1408 ----HSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAA 1459
                   +  T T++  G  YV  + A N    G E    +   +   +  P++L     
Sbjct: 871  LEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGT 930

Query: 1460 TPTSLLISWDAPAVTVRY-----YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVD 1513
            T TS+ +SW  P +  R      Y + Y +      P+++  VP   +T T++GLKP   
Sbjct: 931  TSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPAD-TTMTLTGLKPDTT 989

Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
            Y + V A T +G  P S    S+ +RT       + V  V   +  VK +  +S +  + 
Sbjct: 990  YDVKVRAHTSKGPGPYSP---SVQFRT-------LPVDQVFAKNFHVKAVMKTSVLLSWE 1039

Query: 1574 VTTTPKNGPGPTKTKTAGPD----------QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
            +   P+N       K    D           T+  I  L+P   Y    +     G S  
Sbjct: 1040 I---PENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSY---SFVLTNRGNSAG 1093

Query: 1624 LVQTAVTTIPAPTDL--KFTQVTPTSLSAQWT------PPNVQLTGYRVRVTPKEKT 1672
             +Q  VT   AP  L  K   +  T+L    T      P N  + GY + + P +K+
Sbjct: 1094 GLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKS 1150



 Score =  124 bits (311), Expect = 1e-27
 Identities = 159/710 (22%), Positives = 292/710 (41%), Gaps = 81/710 (11%)

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
            ++T  + ST      +   T    P    +  VTE TA+S  ++W S + + VS + +++
Sbjct: 299  NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 358

Query: 755  ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
            +   +  E  Y ++   AT+  ++  L P   Y   V  ++  G     + ++  TS+  
Sbjct: 359  K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 416

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
               AP D     +  T+I+V+W  P+ P   I GYR+ Y+  P+   ++   +    +  
Sbjct: 417  PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 476

Query: 865  VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
             T+ +L P   Y++ + A   + +   S+ + VI Q  TG P       P + +    ++
Sbjct: 477  TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 529

Query: 921  VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
              + + WTPP S  +  Y +    V   GEHG  QR+ I   T   + GL P   YYF++
Sbjct: 530  TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 585

Query: 978  FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
             A S    G  +  ++A+  Q+     P ++   + + +++LV W PP  +     IT Y
Sbjct: 586  AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645

Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
              + T       +P +    PS  +KY L  L+  +EY +++ A       P++  V   
Sbjct: 646  SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 705

Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLG-VRPSQGGEAPREVT 1132
            T +   S PP   E   V  T++ ++W +P P        G+++  VR   G    + + 
Sbjct: 706  TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765

Query: 1133 SD--------------SGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLS 1175
             D                 +++SGL P   Y  T+       DG      +V+       
Sbjct: 766  KDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPG 825

Query: 1176 PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
             P  +      +T ++       T   + GYR+     + +   +LE     D  + T  
Sbjct: 826  KPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDI 885

Query: 1236 NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMRVTWAPPPS 1292
            +      + +S        E + + +  IP   P   P +L        +++++W PP  
Sbjct: 886  HKGASYVFRLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVL 944

Query: 1293 IDLTNFLVRYSPVKNEEDV----AELSISPSDNAVVLTNLLPGTEYVVSV 1338
             +    + +Y+ +  + ++     E  I P+D  + LT L P T Y V V
Sbjct: 945  AERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 994



 Score =  102 bits (253), Expect = 5e-21
 Identities = 156/697 (22%), Positives = 258/697 (37%), Gaps = 102/697 (14%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
            T S   S  + W++  P  +S YI++ +PKNS   +KE  I G   + Y++ GL P   Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 389

Query: 678  EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
            E +++++   G              S PV   T T E  P S           +++++ +
Sbjct: 390  EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 435

Query: 738  VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
            V W    +    + G+RV Y +        ++      + +  I +L+P + Y V V   
Sbjct: 436  VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 495

Query: 794  SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
            +  G+  L   I   +QT  P  P +   +   +TSI++ W+ P++  I  Y +VY    
Sbjct: 496  TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 555

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
             G    + + E   S  L  L+P   Y   + A   + +       + +  T +S     
Sbjct: 556  HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 612

Query: 910  PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
            P+D+     +   + + W PP        +T Y +    V+  GE  +          E+
Sbjct: 613  PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 662

Query: 965  TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
             G+    T Y          +++   +H   G   + L+    T  D P+       ++ 
Sbjct: 663  LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 722

Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV------------ 1048
            VN T  +V V W  P       QI GY++       G+P+   +   V            
Sbjct: 723  VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDT 780

Query: 1049 --SKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTI 1103
                  +  LQP + Y  TV+    KG+    K   V TT   PG      N      T 
Sbjct: 781  TEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTA 839

Query: 1104 VITWTP-----APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLR 1157
            +I W P      P  G++L   R         E +        + +  G  YV+ +    
Sbjct: 840  LIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARN 899

Query: 1158 D---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITT 1210
                G+E    I      P   P NLH E    T V  +SW+     +    IT Y +  
Sbjct: 900  KVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLY 958

Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
               N       + +V AD ++ T   L P   Y+V V
Sbjct: 959  RDINIPLLPMEQLIVPAD-TTMTLTGLKPDTTYDVKV 994



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 75/332 (22%), Positives = 131/332 (39%), Gaps = 43/332 (12%)

Query: 1708 TLTSRPAQGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVP 1760
            T  +    GV+  +  ++      PP    VT++T T+IT++W +   E ++ + +   P
Sbjct: 301  TCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKP 360

Query: 1761 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVIDAS--TAIDA 1815
             N +   +         Y++ GL P +DY+  +  +N+  R   S PV+   S      A
Sbjct: 361  KNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSA 420

Query: 1816 PSNLRFLATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT- 1871
            P +++    +  ++LV W   + P  +I GY + Y     P + V    +  V ++ IT 
Sbjct: 421  PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM--DPTQHVNNWMKHNVADSQITT 478

Query: 1872 --GLEPGTEYTIYVIAL----------------KNNQKSEPLIGRKKTGQEALSQTTISW 1913
               L P   Y++ V+A                 +     +PL    K   E+ +   +SW
Sbjct: 479  IGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPL--NFKAEPESETSILLSW 536

Query: 1914 A-PFQDTSEYIISCHPVGTDEEPLQFRV-PGTSTSATLTGLTRGATYNIIVEALKDQQRH 1971
              P  DT       +  G   E  +  + PG  TS  L GL   + Y   + A   Q   
Sbjct: 537  TPPRSDTIANYELVYKDGEHGEEQRITIEPG--TSYRLQGLKPNSLYYFRLAARSPQGLG 594

Query: 1972 KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003
                E ++     ++    P D SC  P + S
Sbjct: 595  ASTAE-ISARTMQSKPSAPPQDISCTSPSSTS 625


>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
            precursor [Homo sapiens]
          Length = 1899

 Score =  145 bits (367), Expect = 3e-34
 Identities = 158/671 (23%), Positives = 270/671 (40%), Gaps = 79/671 (11%)

Query: 1367 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1424
            ++ TA S T+ W +     ++ Y I+H P++     +E D V  +R S+    L+P ++Y
Sbjct: 319  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 376

Query: 1425 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1476
               +VA+N    G    P+L    +   S  PRD++    + T++L+ W   + P   ++
Sbjct: 377  EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 436

Query: 1477 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
             YR+ Y    T   +   +  V  S+ T TI  L P   Y++ V A T  GD P SS   
Sbjct: 437  GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 495

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
             I       +P   +     + SI + W  P S  +  Y +    K+G    + +     
Sbjct: 496  VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 553

Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA-----PTDLKFTQVTPTSL 1648
             T   ++GL+P   Y   + A++P G      + +  T+ +     P D+  T  + TS+
Sbjct: 554  GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 613

Query: 1649 SAQWTPPNVQ-----LTGYRVRVT--PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1701
               W PP V+     +T Y ++ T    E   P + + +  D++  ++  L   T+Y ++
Sbjct: 614  LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 673

Query: 1702 VYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET-----ITG 1753
            V A  D      +  V + T E+V   PPR+  V     T++ +SWR+         I G
Sbjct: 674  VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 733

Query: 1754 FQVDAVPANGQTPIQRTIKPDV--------------RSYTITGLQPGTDYKIYL---YTL 1796
            +QV  V      P  + +  DV                  I+GLQP T Y + +    T 
Sbjct: 734  YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 793

Query: 1797 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP---RARITGYIIKYEKPGSP 1853
             D ARS P ++  + A+     L    T  N+ L+ W PP      + GY +K+ +    
Sbjct: 794  GDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDME 853

Query: 1854 PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQE--------- 1904
            P   +          T T +  G  Y   + A       E ++      +E         
Sbjct: 854  PLTTLEFSEK-EDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNL 912

Query: 1905 -----ALSQTTISWAP------FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLT 1953
                   +   +SW P          ++Y +    +     P++  +    T+ TLTGL 
Sbjct: 913  HSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLK 972

Query: 1954 RGATYNIIVEA 1964
               TY++ V A
Sbjct: 973  PDTTYDVKVRA 983



 Score =  135 bits (339), Expect = 6e-31
 Identities = 212/919 (23%), Positives = 362/919 (39%), Gaps = 138/919 (15%)

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
            E  + E ++P   N + L+D++    Y            ST  VI+     T ++  +P 
Sbjct: 261  EDLTPEDDMPIGRNVLELNDVRQSANYTCVAM-------STLGVIEAIAQITVKA--LPK 311

Query: 910  PRDLQFV-EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLS 968
            P     V E T   +T+ W         Y +         E  + +     T   V GLS
Sbjct: 312  PPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLS 371

Query: 969  PGVTYYFKVFAVSH---GRESKPLTAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR-- 1021
            P   Y F+V AV++   G  S+P+  Q + +    AP ++Q    + +T+LV+W  P   
Sbjct: 372  PYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP 431

Query: 1022 -AQITGYRL--TVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK 1077
              QI GYR+  T+  T+      ++NV  S     + NL P   Y+V ++A     + P 
Sbjct: 432  NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPL 490

Query: 1078 ATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAPR----IGFKLGVRPSQGGEAPRE 1130
            ++ +    Q G    P N +    +ET+I+++WTP PR      ++L  +  + GE  R 
Sbjct: 491  SSDIQVITQTGVPGQPLNFKAEPESETSILLSWTP-PRSDTIANYELVYKDGEHGEEQRI 549

Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT-----PLSPPTNLHLEAN 1185
                  S  + GL P   Y + +   R  Q   A             P +PP ++   + 
Sbjct: 550  TIEPGTSYRLQGLKPNSLYYFRLAA-RSPQGLGASTAEISARTMQSKPSAPPQDISCTSP 608

Query: 1186 PDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPG 1240
              T +L VSW+          IT Y I  T  +G+     E + + +D +    + L   
Sbjct: 609  SSTSIL-VSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKW 667

Query: 1241 LEYNVSVYTVKD---DKESVPISDTIIPAVP--PPTDLRFTNIGPDTMRVTW-APPPSID 1294
             EY ++V    D     ES+ +       VP  PP  +    +   +++V+W +P P+  
Sbjct: 668  TEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ 727

Query: 1295 ---LTNFLVRYSPVKNEEDVAELSISP-------------SDNAVVLTNLLPGTEYVVSV 1338
               +  + V Y  ++N E   +  +               +++ ++++ L P T Y ++V
Sbjct: 728  HGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTV 787

Query: 1339 SSVYEQHESTPLRGRQKTGLDSPTG-------IDFSDITANSFTVHWIAPRAT---ITGY 1388
            ++   + +      R K  L S TG       +  +    N+  + W  P  T   + GY
Sbjct: 788  TAYTTKGDGA----RSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGY 843

Query: 1389 RIRHHPEHFSGRPREDRVP-------HSRNSITLTNLTPGTEYVVSIVALN----GREES 1437
            R++          R+D  P          +  T T++  G  YV  + A N    G E  
Sbjct: 844  RLKFG--------RKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMV 895

Query: 1438 PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY-----YRITYGETG-GNSPV 1491
              +   +   +  P++L     T TS+ +SW  P +  R      Y + Y +      P+
Sbjct: 896  KEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPM 955

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1551
            ++  VP   +T T++GLKP   Y + V A T +G  P S    S+ +RT       + V 
Sbjct: 956  EQLIVPAD-TTMTLTGLKPDTTYDVKVRAHTSKGPGPYSP---SVQFRT-------LPVD 1004

Query: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD----------QTEMTIEG 1601
             V   +  VK +  +S +  + +   P+N       K    D           T+  I  
Sbjct: 1005 QVFAKNFHVKAVMKTSVLLSWEI---PENYNSAMPFKILYDDGKMVEEVDGRATQKLIVN 1061

Query: 1602 LQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDL--KFTQVTPTSLSAQWT------ 1653
            L+P   Y    +     G S   +Q  VT   AP  L  K   +  T+L    T      
Sbjct: 1062 LKPEKSY---SFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEV 1118

Query: 1654 PPNVQLTGYRVRVTPKEKT 1672
            P N  + GY + + P +K+
Sbjct: 1119 PANENIKGYYIIIVPLKKS 1137



 Score =  124 bits (311), Expect = 1e-27
 Identities = 159/710 (22%), Positives = 292/710 (41%), Gaps = 81/710 (11%)

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
            ++T  + ST      +   T    P    +  VTE TA+S  ++W S + + VS + +++
Sbjct: 286  NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 345

Query: 755  ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
            +   +  E  Y ++   AT+  ++  L P   Y   V  ++  G     + ++  TS+  
Sbjct: 346  K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 403

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
               AP D     +  T+I+V+W  P+ P   I GYR+ Y+  P+   ++   +    +  
Sbjct: 404  PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 463

Query: 865  VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
             T+ +L P   Y++ + A   + +   S+ + VI Q  TG P       P + +    ++
Sbjct: 464  TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 516

Query: 921  VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
              + + WTPP S  +  Y +    V   GEHG  QR+ I   T   + GL P   YYF++
Sbjct: 517  TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 572

Query: 978  FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
             A S    G  +  ++A+  Q+     P ++   + + +++LV W PP  +     IT Y
Sbjct: 573  AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 632

Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
              + T       +P +    PS  +KY L  L+  +EY +++ A       P++  V   
Sbjct: 633  SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 692

Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLG-VRPSQGGEAPREVT 1132
            T +   S PP   E   V  T++ ++W +P P        G+++  VR   G    + + 
Sbjct: 693  TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 752

Query: 1133 SD--------------SGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLS 1175
             D                 +++SGL P   Y  T+       DG      +V+       
Sbjct: 753  KDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPG 812

Query: 1176 PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
             P  +      +T ++       T   + GYR+     + +   +LE     D  + T  
Sbjct: 813  KPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDI 872

Query: 1236 NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMRVTWAPPPS 1292
            +      + +S        E + + +  IP   P   P +L        +++++W PP  
Sbjct: 873  HKGASYVFRLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVL 931

Query: 1293 IDLTNFLVRYSPVKNEEDV----AELSISPSDNAVVLTNLLPGTEYVVSV 1338
             +    + +Y+ +  + ++     E  I P+D  + LT L P T Y V V
Sbjct: 932  AERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 981



 Score =  102 bits (253), Expect = 5e-21
 Identities = 156/697 (22%), Positives = 258/697 (37%), Gaps = 102/697 (14%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
            T S   S  + W++  P  +S YI++ +PKNS   +KE  I G   + Y++ GL P   Y
Sbjct: 319  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 376

Query: 678  EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
            E +++++   G              S PV   T T E  P S           +++++ +
Sbjct: 377  EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 422

Query: 738  VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
            V W    +    + G+RV Y +        ++      + +  I +L+P + Y V V   
Sbjct: 423  VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 482

Query: 794  SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
            +  G+  L   I   +QT  P  P +   +   +TSI++ W+ P++  I  Y +VY    
Sbjct: 483  TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 542

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
             G    + + E   S  L  L+P   Y   + A   + +       + +  T +S     
Sbjct: 543  HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 599

Query: 910  PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
            P+D+     +   + + W PP        +T Y +    V+  GE  +          E+
Sbjct: 600  PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 649

Query: 965  TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
             G+    T Y          +++   +H   G   + L+    T  D P+       ++ 
Sbjct: 650  LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 709

Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV------------ 1048
            VN T  +V V W  P       QI GY++       G+P+   +   V            
Sbjct: 710  VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDT 767

Query: 1049 --SKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTI 1103
                  +  LQP + Y  TV+    KG+    K   V TT   PG      N      T 
Sbjct: 768  TEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTA 826

Query: 1104 VITWTP-----APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLR 1157
            +I W P      P  G++L   R         E +        + +  G  YV+ +    
Sbjct: 827  LIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARN 886

Query: 1158 D---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITT 1210
                G+E    I      P   P NLH E    T V  +SW+     +    IT Y +  
Sbjct: 887  KVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLY 945

Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
               N       + +V AD ++ T   L P   Y+V V
Sbjct: 946  RDINIPLLPMEQLIVPAD-TTMTLTGLKPDTTYDVKV 981



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 75/332 (22%), Positives = 131/332 (39%), Gaps = 43/332 (12%)

Query: 1708 TLTSRPAQGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVP 1760
            T  +    GV+  +  ++      PP    VT++T T+IT++W +   E ++ + +   P
Sbjct: 288  TCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKP 347

Query: 1761 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVIDAS--TAIDA 1815
             N +   +         Y++ GL P +DY+  +  +N+  R   S PV+   S      A
Sbjct: 348  KNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSA 407

Query: 1816 PSNLRFLATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT- 1871
            P +++    +  ++LV W   + P  +I GY + Y     P + V    +  V ++ IT 
Sbjct: 408  PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM--DPTQHVNNWMKHNVADSQITT 465

Query: 1872 --GLEPGTEYTIYVIAL----------------KNNQKSEPLIGRKKTGQEALSQTTISW 1913
               L P   Y++ V+A                 +     +PL    K   E+ +   +SW
Sbjct: 466  IGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPL--NFKAEPESETSILLSW 523

Query: 1914 A-PFQDTSEYIISCHPVGTDEEPLQFRV-PGTSTSATLTGLTRGATYNIIVEALKDQQRH 1971
              P  DT       +  G   E  +  + PG  TS  L GL   + Y   + A   Q   
Sbjct: 524  TPPRSDTIANYELVYKDGEHGEEQRITIEPG--TSYRLQGLKPNSLYYFRLAARSPQGLG 581

Query: 1972 KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003
                E ++     ++    P D SC  P + S
Sbjct: 582  ASTAE-ISARTMQSKPSAPPQDISCTSPSSTS 612


>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
            isoform 1 precursor [Homo sapiens]
          Length = 1948

 Score =  143 bits (360), Expect = 2e-33
 Identities = 164/676 (24%), Positives = 268/676 (39%), Gaps = 88/676 (13%)

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1429
            TA S T+ W +       Y +  +       P + +   +    ++  L+P +EY + + 
Sbjct: 344  TATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVS 403

Query: 1430 ALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRYYRI 1480
            A+N   + P         G+Q+  S  PR+++    + T++++ W+ P      +R YR+
Sbjct: 404  AVNSIGQGPPSESVVTRTGEQAPAS-APRNVQARMLSATTMIVQWEEPVEPNGLIRGYRV 462

Query: 1481 TYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
             Y       PV   Q+  V  S  T T+  L     YT+ V A T  GD P S  PI + 
Sbjct: 463  YY-TMEPEHPVGNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSD-PIQVK 519

Query: 1538 YRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
             +  +  +P  ++     + SI++ W P              +   G    +T  P  T 
Sbjct: 520  TQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPT-TS 578

Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQ--PLV-QTAVTTIPA--PTDLKFTQVTPTSLSAQ 1651
              +E L+P  EY   + A++P G     P+V Q  + + P+  P D+K   V  T++   
Sbjct: 579  YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVS 638

Query: 1652 WTPP-----NVQLTGYRVRVTPKEKTGPM-KEIN-LAPDSSSVVVSGLMVATKYEVSVYA 1704
            W PP     N  L GY VR  P     P  KE+N + P ++ +++  L   T+Y ++  A
Sbjct: 639  WRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVA 698

Query: 1705 LKDTLTSRPAQGVVT-TLENV--SPPRRARVTDATETTITISWRTKTE-----TITGFQV 1756
              +      +  VV  T E+V  +PPR+        T I + WR+         I G+QV
Sbjct: 699  HTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQV 758

Query: 1757 -----DAVPANGQTPIQRTIKPDVRSYT---------ITGLQPGTDYKIYL--YTLN-DN 1799
                 +   A G   I+  +  D +  T         IT LQP T Y I +  YT+  D 
Sbjct: 759  HYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDG 818

Query: 1800 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPR 1855
            ARS P V+    A+     L    T   SLL  W+PP      ++ GY +++ +  S P 
Sbjct: 819  ARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPL 878

Query: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIAL----------------KNNQKSEPLIGRK 1899
              +  P P     T +G+  G  Y   + A                 ++  +  P I  +
Sbjct: 879  ATLEFP-PSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQI-LE 936

Query: 1900 KTGQEALSQTTISWAPFQDTS------EYIISCHPVGT-----DEEPLQFRVPGTSTSAT 1948
              G  +     + W P           +Y ++    G      + E      PG   + T
Sbjct: 937  AAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALT 996

Query: 1949 LTGLTRGATYNIIVEA 1964
            L GL     Y++ V A
Sbjct: 997  LQGLKPDTAYDLQVRA 1012



 Score =  124 bits (311), Expect = 1e-27
 Identities = 195/889 (21%), Positives = 339/889 (38%), Gaps = 113/889 (12%)

Query: 752  VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
            ++ E SEE D+ +Y  + + +  V      P   Y+  + ++     +  IL  S    P
Sbjct: 201  LQIESSEETDQGKYECVATNSAGVRYSS--PANLYVRELREVRRVAPRFSILPMSHEIMP 258

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
                + T   V      V+W +                E  + E ++P   N + L+D++
Sbjct: 259  GGNVNITCVAVGSPMPYVKWMQ--------------GAEDLTPEDDMPVGRNVLELTDVK 304

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
                Y     +     E+   V Q      P++   P        E T   +TI W    
Sbjct: 305  DSANYTCVAMSSLGVIEA---VAQITVKSLPKAPGTP-----MVTENTATSITITWDSGN 356

Query: 932  -SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
               V+ Y ++    +  G +  +  I+   ++ + GLSP   Y   V AV+   +  P  
Sbjct: 357  PDPVSYYVIEYKSKSQDGPYQIKEDITTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSE 415

Query: 991  AQQT-----TKLDAPTNLQFVNETDSTVLVRW---TPPRAQITGYRLTVGLTRR---GQP 1039
            +  T         AP N+Q    + +T++V+W     P   I GYR+   +      G  
Sbjct: 416  SVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNW 475

Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
            +++NV  S+    + +L     YTV ++A     + P +  +    Q G    P N    
Sbjct: 476  QKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAE 534

Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
              +ET+I ++W+P PR    I ++L  R    G         + S VV  L P  EY + 
Sbjct: 535  ARSETSITLSWSP-PRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFR 593

Query: 1153 IQVLR-DGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERSTTPD-----I 1203
            +      G     P+V +      P +PP ++   +   T +L VSW R   P+     +
Sbjct: 594  LAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL-VSW-RPPPPETHNGAL 651

Query: 1204 TGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPI 1259
             GY +   P   +     E   +    +    + L    +Y ++      V    ES P+
Sbjct: 652  VGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPV 711

Query: 1260 ---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEED-- 1310
               +D  +P+ PP   +    +    +RV W +P P      +  + V Y  ++  E   
Sbjct: 712  VVRTDEDVPSAPP-RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARG 770

Query: 1311 --------VAELSISPSDNA---VVLTNLLPGTEYVVSVSSVYEQHESTPLRGR----QK 1355
                    +A+      D A   +V+TNL P T Y ++V++   + +    + +    + 
Sbjct: 771  PPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKG 830

Query: 1356 TGLDSPTGIDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRN 1411
              L  PT +        S    W  P  T    + GYR++   E  +     +  P S +
Sbjct: 831  AVLGRPT-LSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLE-FPPSED 888

Query: 1412 SITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA-ATPTSLLI 1466
              T + +  G  YV  + A +    G E + +L   + T    P+ LE    A+  ++L+
Sbjct: 889  RYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLL 948

Query: 1467 SWDAPAVTVRY-----YRITYGETGGNSPVQEFTVP-----GSKSTATISGLKPGVDYTI 1516
             W  P    R      Y +   E G   P +E  +P     G+++  T+ GLKP   Y +
Sbjct: 949  RWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDL 1008

Query: 1517 TVYAVTGRGDSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW 1562
             V A T RG  P S     + YRT +     P   +V  +   S+ + W
Sbjct: 1009 QVRAHTRRGPGPFSP---PVRYRTFLRDQVSPKNFKVKMIMKTSVLLSW 1054



 Score =  105 bits (262), Expect = 5e-22
 Identities = 179/808 (22%), Positives = 327/808 (40%), Gaps = 100/808 (12%)

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
            ++T  + S+      V   T    P    +  VTE TA+S  ++W S + D VS + +EY
Sbjct: 308  NYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEY 367

Query: 755  ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTA 810
            + S+  D P  +    T T  +I  L P  +Y + V  ++  G+    +S++  T +   
Sbjct: 368  K-SKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAP 426

Query: 811  PDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYSPSVE---GSSTELNLPETANS 864
              AP +     +  T+++V+W  P  P   I GYR+ Y+   E   G+  + N+ ++   
Sbjct: 427  ASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSL-L 485

Query: 865  VTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDV 921
             T+  L     Y + + A   V +   S P+ ++ +  G P       P +L+    ++ 
Sbjct: 486  TTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ-QGVP-----GQPMNLRAEARSET 539

Query: 922  KVTIMWTPP-ESAVTGYRVDVIPVNLPGEHGQRL--PISRNTFAEVTGLSPGVTYYFKVF 978
             +T+ W+PP + ++  Y +    +   G+HG+ +       T   V  L P   Y F++ 
Sbjct: 540  SITLSWSPPRQESIIKYEL----LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLA 595

Query: 979  AVS-HGRES-KPLTAQQTTKLD---APTNLQFVNETDSTVLVRWTPP-----RAQITGY- 1027
            A S  G  +  P+  Q+T +      P +++ V+   + +LV W PP        + GY 
Sbjct: 596  ARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYS 655

Query: 1028 -RLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-T 1084
             R     +   +P++ N + P+ ++  L  L+  ++Y ++ VA       P+++ V   T
Sbjct: 656  VRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRT 715

Query: 1085 LQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEA--PREV- 1131
             +   S PP   E   +  T I + W +PAP        G+++     +G EA  P  + 
Sbjct: 716  DEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIK 775

Query: 1132 ----------TSDSG--SIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSP 1176
                      T D+    +V++ L P   Y  T+       DG      +V      L  
Sbjct: 776  DVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGR 835

Query: 1177 PTNLHLEANPDTGVLTVSWE--RSTTPD-ITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            PT L ++  P+ G L   WE    T  D + GYR+     +     +LE     D+ + +
Sbjct: 836  PT-LSVQQTPE-GSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTAS 893

Query: 1234 FDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
              +      + ++  +   + ++   V       P   P       N    T+ + W PP
Sbjct: 894  GVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPP 953

Query: 1291 PSIDLTNFLVRYSPV---------KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
               +    +V+Y+             E ++   +   ++NA+ L  L P T Y + V + 
Sbjct: 954  VPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAH 1013

Query: 1342 YEQHE---STPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAP--RATITGYRIRHH-- 1393
              +     S P+R R       SP       I   S  + W  P    + T Y+I+++  
Sbjct: 1014 TRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGL 1073

Query: 1394 PEHFSGRPREDRV----PHSRNSITLTN 1417
                 GR  +  +    PH+  +  LTN
Sbjct: 1074 TLDVDGRTTKKLITHLKPHTFYNFVLTN 1101



 Score =  100 bits (250), Expect = 1e-20
 Identities = 188/800 (23%), Positives = 302/800 (37%), Gaps = 129/800 (16%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRW--KEATIPGHLNSYTIKGLKPGVV 676
            T +   S  I W++  P  +S Y++ ++ K+  G +  KE         Y+I GL P   
Sbjct: 341  TENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSE 397

Query: 677  YEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSF 736
            YE  + ++   G    +             +  T TGE  P S     +     ++A++ 
Sbjct: 398  YEIWVSAVNSIGQGPPSE------------SVVTRTGEQAPAS--APRNVQARMLSATTM 443

Query: 737  VVSW---VSASDTVSGFRVEYELSEE---GDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
            +V W   V  +  + G+RV Y +  E   G+  ++    S  T+V    LL    Y V V
Sbjct: 444  IVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVG--SLLEDETYTVRV 501

Query: 791  YQISEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP-QAPITGYRIVYS 846
               +  G+  L   I   +Q   P  P +   +   +TSI + WS P Q  I  Y +++ 
Sbjct: 502  LAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFR 561

Query: 847  PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN--QESTPVVIQQETTGTPRS 904
                G         T  S  + DL+P  +Y   + A         TPVV Q+     P +
Sbjct: 562  EGDHGREVGRTFDPT-TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSA 620

Query: 905  DTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P+D++ V V    + + W PP       A+ GY V   P+      G   P  + 
Sbjct: 621  ----PPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPL------GSEDPEPK- 669

Query: 960  TFAEVTGLSPGVTY----------YFKVFAVSH-----GRESKPLTAQQTTKLDAPT--- 1001
               EV G+ P  T            +++  V+H     G ES P+  +  T  D P+   
Sbjct: 670  ---EVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVR--TDEDVPSAPP 724

Query: 1002 ---NLQFVNETDSTVLVRWTPP---RAQITGYRL----TVGLTRRGQPRQYNVGPSVSKY 1051
                 + +N T   VL R   P     QI GY++      G   RG PR  +V  + +++
Sbjct: 725  RKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQW 784

Query: 1052 P----------LRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQPGSSI--PPYNTE 1097
                       + NLQP + Y++++ A  +KG+    K   V T    G+ +  P  + +
Sbjct: 785  ETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVT---KGAVLGRPTLSVQ 841

Query: 1098 VT-ETTIVITWTPAPRIGFK--LGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEY 1149
             T E +++  W P         LG R   G E     A  E          SG+  G  Y
Sbjct: 842  QTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATY 901

Query: 1150 VYTIQV-LRDGQERDAPIVNKVV--TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY 1206
            V+ +    R G   +A  V  +   TP   P  L    N   G + + W      +  G 
Sbjct: 902  VFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGA 961

Query: 1207 RITTTPT---NGQQGNSLEEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
             +  T      G  G + E  + A      +++ T   L P   Y++ V      +   P
Sbjct: 962  IVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQV-RAHTRRGPGP 1020

Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT-NFLVRY---SPVKNEEDVAEL 1314
             S    P V   T LR   + P   +V      S+ L+  F   Y   +P K + +   L
Sbjct: 1021 FS----PPVRYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTL 1075

Query: 1315 SISPSDNAVVLTNLLPGTEY 1334
             +       ++T+L P T Y
Sbjct: 1076 DVDGRTTKKLITHLKPHTFY 1095



 Score = 34.7 bits (78), Expect = 1.0
 Identities = 87/407 (21%), Positives = 148/407 (36%), Gaps = 89/407 (21%)

Query: 1644 TPTSLSAQWTPPNVQLTGYR--VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT----- 1696
            T T L A    P+ ++T ++  + V P    G +K++      S+ +   L + +     
Sbjct: 151  TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETD 210

Query: 1697 --KYEVSVYALKDTLTSRPAQGVVTTLENVSP--------PRRARVTDATETTIT----- 1741
              KYE           S PA   V  L  V          P    +       IT     
Sbjct: 211  QGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVG 270

Query: 1742 -----ISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
                 + W    E +T    D +P  G+  ++ T   D  +YT                 
Sbjct: 271  SPMPYVKWMQGAEDLT--PEDDMPV-GRNVLELTDVKDSANYTCV--------------- 312

Query: 1797 NDNARSSPVVIDASTAID------APSNLRFLATTPNSLLVSWQPPRAR-ITGYIIKYE- 1848
               A SS  VI+A   I       AP        T  S+ ++W       ++ Y+I+Y+ 
Sbjct: 313  ---AMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEYKS 369

Query: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN---NQKSEPLIGRKKTGQEA 1905
            K    P ++  +     T  +I GL P +EY I+V A+ +      SE ++ R  TG++A
Sbjct: 370  KSQDGPYQI--KEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTR--TGEQA 425

Query: 1906 LSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE-- 1963
             +      AP    +  + +   +   EEP++             GL RG      +E  
Sbjct: 426  PAS-----APRNVQARMLSATTMIVQWEEPVE-----------PNGLIRGYRVYYTMEPE 469

Query: 1964 -ALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGD 2009
              + + Q+H V + ++T   S+ E       D  +    ++  +VGD
Sbjct: 470  HPVGNWQKHNVDDSLLTTVGSLLE-------DETYTVRVLAFTSVGD 509


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,453,132
Number of Sequences: 37866
Number of extensions: 5166041
Number of successful extensions: 22094
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 10341
Number of HSP's gapped (non-prelim): 3428
length of query: 2176
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2058
effective length of database: 13,779,330
effective search space: 28357861140
effective search space used: 28357861140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.