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Search of human proteins with 46852174
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46852174 kinesin family member 3A [Homo sapiens]
(699 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46852174 kinesin family member 3A [Homo sapiens] 1375 0.0
gi|4758646 kinesin family member 3B [Homo sapiens] 668 0.0
gi|41352705 kinesin family member 3C [Homo sapiens] 567 e-161
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 447 e-125
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 447 e-125
gi|13699824 kinesin family member 11 [Homo sapiens] 338 1e-92
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 304 2e-82
gi|45446749 kinesin family member 5A [Homo sapiens] 301 1e-81
gi|9910266 kinesin family member 15 [Homo sapiens] 301 1e-81
gi|150010604 kinesin family member 4B [Homo sapiens] 301 2e-81
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 300 2e-81
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 300 2e-81
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 300 2e-81
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 300 2e-81
gi|4758650 kinesin family member 5C [Homo sapiens] 300 3e-81
gi|46852172 kinesin family member 13B [Homo sapiens] 300 3e-81
gi|116686122 kinesin family member 4 [Homo sapiens] 299 5e-81
gi|4758648 kinesin family member 5B [Homo sapiens] 290 4e-78
gi|71061468 centromere protein E [Homo sapiens] 288 1e-77
gi|40254834 kinesin family member 1C [Homo sapiens] 287 2e-77
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 283 4e-76
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 283 4e-76
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 279 7e-75
gi|30794488 kinesin family member 27 [Homo sapiens] 270 3e-72
gi|38569484 kinesin family member 21A [Homo sapiens] 266 6e-71
gi|83716024 kinesin family member 21B [Homo sapiens] 263 3e-70
gi|148612831 kinesin family member 18A [Homo sapiens] 261 2e-69
gi|157502184 kinesin family member 6 [Homo sapiens] 260 3e-69
gi|122937289 kinesin family member 18B [Homo sapiens] 254 2e-67
gi|156616271 kinesin family member 19 [Homo sapiens] 252 9e-67
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 1375 bits (3560), Expect = 0.0
Identities = 699/699 (100%), Positives = 699/699 (100%)
Query: 1 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 60
MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT
Sbjct: 1 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 60
Query: 61 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR
Sbjct: 61 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
Query: 121 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 180
GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY
Sbjct: 121 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 180
Query: 181 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 240
IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH
Sbjct: 181 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 240
Query: 241 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 300
VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS
Sbjct: 241 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 300
Query: 301 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 360
KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL
Sbjct: 301 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 360
Query: 361 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMI 420
RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMI
Sbjct: 361 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMI 420
Query: 421 EMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI 480
EMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI
Sbjct: 421 EMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI 480
Query: 481 VGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQ 540
VGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQ
Sbjct: 481 VGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQ 540
Query: 541 GKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDY 600
GKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDY
Sbjct: 541 GKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDY 600
Query: 601 QEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTEESL 660
QEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTEESL
Sbjct: 601 QEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTEESL 660
Query: 661 RQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ 699
RQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ
Sbjct: 661 RQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ 699
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 668 bits (1724), Expect = 0.0
Identities = 351/706 (49%), Positives = 493/706 (69%), Gaps = 29/706 (4%)
Query: 8 KPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITV-HKTDSSNEPPKTFTFDTV 66
K +S ++V+VVVRCRP+N +EK+ Y + V VD G ++V + +++E PKTFTFD V
Sbjct: 3 KLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAV 62
Query: 67 FGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNS 126
+ +KQ ++Y+ T RP++DSVL+G+NGTIFAYGQTGTGKT+TMEG+R PE RG+IPNS
Sbjct: 63 YDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNS 122
Query: 127 FAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSA 186
F HIF HI++++ ++LVR SYLEIY EE+RDLL KDQT+RLE+KERPD GVY+KDLS+
Sbjct: 123 FDHIFTHISRSQNQ-QYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSS 181
Query: 187 YVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKL 246
+V + +++ +M +G++NRSVGATNMNEHSSRSHAIF ITIECSE G+DG H+R+GKL
Sbjct: 182 FVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKL 241
Query: 247 HLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLL 306
+LVDLAGSERQAKTGA G+RLKEATKINLSLS LGNVISALVDGKSTH+PYR+SKLTRLL
Sbjct: 242 NLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLL 301
Query: 307 QDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKE 366
QDSLGGN+KT+M AN+GPA YN +ET++TLRYANRAKNIKNK R+NEDPKDALLR+FQ+E
Sbjct: 302 QDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEE 361
Query: 367 IEELKKKLEE---------GEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPD 417
I LK +LE+ + G G E+++EEGE GE+ K D
Sbjct: 362 IARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDK---------DD 412
Query: 418 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 477
E Q K++ E++A+ + EE+ + E EK+ +DL + + + L K+ A+E
Sbjct: 413 YWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMES 472
Query: 478 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE 537
K++VGG +++ EQ+K+LE+ E+ E+++R ++++++E +++E L+++E Y+SLQ+
Sbjct: 473 KLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
Query: 538 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP 597
E KTKKLKK+++ L A K+E+ DLQ+EH +E + L + +L+REL+L+ LII+NFIP
Sbjct: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIP 592
Query: 598 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE 657
+ + I N ++E+ W+L + N + PV K P + E
Sbjct: 593 LEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPE 652
Query: 658 ESLRQS---LMKLERP-RTSKGKARPKTGRRKRSAKPETVIDSLLQ 699
R L++L+ P RT++ P + K + +D+ LQ
Sbjct: 653 ARYRAENIVLLELDMPSRTTRDYEGPAI-----APKVQAALDAALQ 693
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 567 bits (1461), Expect = e-161
Identities = 305/687 (44%), Positives = 448/687 (65%), Gaps = 50/687 (7%)
Query: 6 SEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSS-NEPPKTFTFD 64
+ K ++ + +KVV RCRPL+ +E++ ++Q +++D G +T+ ++ E PKTFTFD
Sbjct: 2 ASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFD 61
Query: 65 TVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIP 124
V+ SKQ D+Y+ T RP+IDSVL+G+NGT+FAYGQTGTGKT+TM+G PELRG+IP
Sbjct: 62 AVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIP 121
Query: 125 NSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDL 184
N+F HIF HI++++ ++LVR SYLEIY EE+RDLL K+ +RLE+KE P+ GVYIKDL
Sbjct: 122 NAFEHIFTHISRSQNQ-QYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL 180
Query: 185 SAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMG 244
S++V N +++ +M LG++ R+VG+T+MNE SSRSHAIF IT+ECSE+G DG H+R+G
Sbjct: 181 SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG 240
Query: 245 KLHLVDLAGSERQAKTG------------------------ATGQRLKEATKINLSLSTL 280
KL+LVDLAGSERQ K G A G+R KEA+KINLSLS L
Sbjct: 241 KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL 300
Query: 281 GNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYAN 340
GNVI+AL +STH+PYR+SKLTRLLQDSLGGN+KT+M A +GPA ++YDE++STLR+AN
Sbjct: 301 GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN 360
Query: 341 RAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEE-------------GEEISGSDISG 387
RAKNIKNK R+NEDPKD LLR+FQ+EI LK +LE+ + + S G
Sbjct: 361 RAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420
Query: 388 SEEDDDEEGEVGEDGEKRKKRR---------GKKKVSPDKMIEMQAKIDEERKALETKLD 438
E E V E+ + +K + + E + +++EE+ A++
Sbjct: 421 YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS 480
Query: 439 MEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLE 498
+ EE+ K E EK +DL + QQ + L K A+E K+++GG +++ EQ+K+LE
Sbjct: 481 LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE 540
Query: 499 ESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKS 558
E+ E+++R ++++E+ +++E +++ YTSLQ+E + KTKKLKK++ L A K+
Sbjct: 541 LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA 600
Query: 559 EMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQ 618
E+ D E+ R + L E + +REL+L+ LII+NFIP + + I N + + + +W+
Sbjct: 601 EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK 660
Query: 619 LKCVAYTG--NNMRKQTPVPDKKEKDP 643
+ + G ++ K+ P K P
Sbjct: 661 FQPLVPAGVSSSQMKKRPTSAVGYKRP 687
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 447 bits (1151), Expect = e-125
Identities = 255/491 (51%), Positives = 333/491 (67%), Gaps = 13/491 (2%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
VKVVVRCRP+N+RE+ + + V+VD R + +++EPPK FTFD + +
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGHI 134
+YN A P+++ V EGYNGTIFAYGQTG+GK+FTM+G+ P RGIIP +F H+F +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFESV 125
Query: 135 AKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADD 194
AE +T+FLVR SYLEIYNE+VRDLLG D Q+LE+KE P+ GVY+K LS + V++
Sbjct: 126 QCAE-NTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVAQ 184
Query: 195 MDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGS 254
+ IM G KNRSVG T MN+ SSRSH+IFTI+IE S G H+R GKL+LVDLAGS
Sbjct: 185 CEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGS 244
Query: 255 ERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNS 314
ERQ+KTGATG+RLKEATKINLSLS LGNVISALVDG+ HVPYR+SKLTRLLQDSLGGN+
Sbjct: 245 ERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLGGNT 304
Query: 315 KTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKL 374
KT+M A + PAD NYDET+STLRYANRAKNI+NK RINEDPKDALLR++Q+EI++LK L
Sbjct: 305 KTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAIL 364
Query: 375 EEGEEISGSDISG--SEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKA 432
+++S S +S S + + +V E K + + D E Q I EE +
Sbjct: 365 T--QQMSPSSLSALLSRQVPPDPVQVEE------KLLPQPVIQHDVEAEKQL-IREEYEE 415
Query: 433 LETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEE 492
+L + + ++RA LE+ + + S LE+ E + ++ V +L KAE
Sbjct: 416 RLARLKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVL-QVGVLYKAEV 474
Query: 493 QEKLLEESNME 503
+ S+ E
Sbjct: 475 MSRAEFASSAE 485
Score = 62.4 bits (150), Expect = 1e-09
Identities = 58/185 (31%), Positives = 92/185 (49%), Gaps = 15/185 (8%)
Query: 464 EHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQ 523
+ Q +L +L LE++V VGG AK ++ ++ + +ERRK QL L+ ++
Sbjct: 737 DQQQVLARLQLLEQQV-VGGEQ--AKNKDLKEKHKRRKRYADERRK---QLVAALQNSDE 790
Query: 524 ERLD--IEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQL 581
+ D + Y S+QEE + K+K L+K+ L AA+ E+ DLQ E Q E L IR+
Sbjct: 791 DSGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQ 850
Query: 582 SRE-LRLQMLI--IDNFIPRDYQ----EMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTP 634
R+ + LQ L+ + I RD E I W+ED G W++ T ++ +
Sbjct: 851 ERDSMLLQQLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKIPHPVITKTSLPVVST 910
Query: 635 VPDKK 639
P K
Sbjct: 911 GPQNK 915
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 447 bits (1151), Expect = e-125
Identities = 255/491 (51%), Positives = 333/491 (67%), Gaps = 13/491 (2%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
VKVVVRCRP+N+RE+ + + V+VD R + +++EPPK FTFD + +
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGHI 134
+YN A P+++ V EGYNGTIFAYGQTG+GK+FTM+G+ P RGIIP +F H+F +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFESV 125
Query: 135 AKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADD 194
AE +T+FLVR SYLEIYNE+VRDLLG D Q+LE+KE P+ GVY+K LS + V++
Sbjct: 126 QCAE-NTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVAQ 184
Query: 195 MDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGS 254
+ IM G KNRSVG T MN+ SSRSH+IFTI+IE S G H+R GKL+LVDLAGS
Sbjct: 185 CEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGS 244
Query: 255 ERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNS 314
ERQ+KTGATG+RLKEATKINLSLS LGNVISALVDG+ HVPYR+SKLTRLLQDSLGGN+
Sbjct: 245 ERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLGGNT 304
Query: 315 KTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKL 374
KT+M A + PAD NYDET+STLRYANRAKNI+NK RINEDPKDALLR++Q+EI++LK L
Sbjct: 305 KTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAIL 364
Query: 375 EEGEEISGSDISG--SEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKA 432
+++S S +S S + + +V E K + + D E Q I EE +
Sbjct: 365 T--QQMSPSSLSALLSRQVPPDPVQVEE------KLLPQPVIQHDVEAEKQL-IREEYEE 415
Query: 433 LETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEE 492
+L + + ++RA LE+ + + S LE+ E + ++ V +L KAE
Sbjct: 416 RLARLKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETEAVL-QVGVLYKAEV 474
Query: 493 QEKLLEESNME 503
+ S+ E
Sbjct: 475 MSRAEFASSAE 485
Score = 61.6 bits (148), Expect = 2e-09
Identities = 55/165 (33%), Positives = 86/165 (52%), Gaps = 15/165 (9%)
Query: 464 EHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQ 523
+ Q +L +L LE++V VGG AK ++ ++ + +ERRK QL L+ ++
Sbjct: 737 DQQQVLARLQLLEQQV-VGGEQ--AKNKDLKEKHKRRKRYADERRK---QLVAALQNSDE 790
Query: 524 ERLD--IEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQL 581
+ D + Y S+QEE + K+K L+K+ L AA+ E+ DLQ E Q E L IR+
Sbjct: 791 DSGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQ 850
Query: 582 SRE-LRLQMLI--IDNFIPRDYQ----EMIENYVHWNEDIGEWQL 619
R+ + LQ L+ + I RD E I W+ED G W++
Sbjct: 851 ERDSMLLQQLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKI 895
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 338 bits (867), Expect = 1e-92
Identities = 224/592 (37%), Positives = 319/592 (53%), Gaps = 65/592 (10%)
Query: 7 EKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPP-KTFTFDT 65
+K E N++VVVRCRP N E+ V D +R ++V +++ KT+TFD
Sbjct: 11 KKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDM 70
Query: 66 VFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPE------- 118
VFG +KQ+DVY PI+D V+ GYN TIFAYGQTGTGKTFTMEG R+ E
Sbjct: 71 VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
Query: 119 -LRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLG--KDQTQRLEVKERP 175
L GIIP + IF + + T F V+VS LEIYNEE+ DLL D ++RL++ + P
Sbjct: 131 PLAGIIPRTLHQIFEKLT--DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDP 188
Query: 176 --DVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEK 233
GV IK L V+N D++ +I+ G R+ AT MN +SSRSH++F++TI E
Sbjct: 189 RNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKET 248
Query: 234 GIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKST 293
IDG V++GKL+LVDLAGSE ++GA +R +EA IN SL TLG VI+ALV+ ++
Sbjct: 249 TIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE-RTP 307
Query: 294 HVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINE 353
HVPYR SKLTR+LQDSLGG ++T + A I PA N +ET+STL YA+RAKNI NK +N+
Sbjct: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
Query: 354 D-PKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKK 412
K AL++++ +EIE LK+ L E +G IS E + GK
Sbjct: 368 KLTKKALIKEYTEEIERLKRDLAAAREKNGVYIS---------------EENFRVMSGKL 412
Query: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKL 472
V ++++E+ KI + L ++ + +N EL++ + DL QE
Sbjct: 413 TVQEEQIVELIEKIGAVEEELNRVTELFMDNKN----ELDQCKSDLQNKTQE-------- 460
Query: 473 SALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKY 532
E +K L+E+ ++L + E + LE E++ D K
Sbjct: 461 -----------------LETTQKHLQETKLQL----VKEEYITSALESTEEKLHDAASKL 499
Query: 533 TSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRE 584
+ EE L A A+ Q + + L N+ +L ++
Sbjct: 500 LNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKD 551
Score = 30.4 bits (67), Expect = 5.8
Identities = 32/150 (21%), Positives = 68/150 (45%), Gaps = 19/150 (12%)
Query: 443 ERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGV--DLLAKAEEQEKLLEES 500
E + E R K++L + +Q L +K E + + DL A E+ + E
Sbjct: 344 EETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEE 403
Query: 501 NMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEM 560
N + + +L +E++ +++ EK +++EE L +V + M K+E+
Sbjct: 404 NFRV---------MSGKLTVQEEQIVELIEKIGAVEEE-------LNRVTELFMDNKNEL 447
Query: 561 ADLQQEHQREIEGLLENIRQLSRELRLQML 590
+ + Q + + LE ++ +E +LQ++
Sbjct: 448 DQCKSDLQNKTQE-LETTQKHLQETKLQLV 476
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 304 bits (778), Expect = 2e-82
Identities = 193/420 (45%), Positives = 246/420 (58%), Gaps = 38/420 (9%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKT------DSSNEPPKTFTFD-TV 66
+VKV VR RP+N REK + K + +++ + TIT K DS E KTFT+D +
Sbjct: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
Query: 67 FGPESKQLD------VYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
+ ++K D V+ ++ S EGYN +FAYGQTG+GK++TM G
Sbjct: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Query: 121 GIIPNSFAHIFGHIAKAE--GDTRFLVRVSYLEIYNEEVRDLLGK--DQTQRLEVKERPD 176
G+IP +F I + + F VSYLEIYNE VRDLL + +T L V+E P
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
Query: 177 VGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGID 236
G Y++DLS ++V N D++ +M G+ NR+ AT MN+ SSRSHAIFTI ++ D
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKF--TQAKFD 237
Query: 237 GNMHVR-MGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD------ 289
M + K+HLVDLAGSER TGATG RLKE IN SL TLGNVISAL D
Sbjct: 238 SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAA 297
Query: 290 -----GKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKN 344
K VPYR+S LT LL+DSLGGNSKT+M A I PAD NY ET+STLRYANRAKN
Sbjct: 298 NTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKN 357
Query: 345 IKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEI----SGSDISGSEEDDDEEGEVGE 400
I NK INED L+R+ + EI LK L +G +I S + +S E+ E V E
Sbjct: 358 IINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQE 417
Score = 59.7 bits (143), Expect = 9e-09
Identities = 62/255 (24%), Positives = 120/255 (47%), Gaps = 34/255 (13%)
Query: 341 RAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGE 400
R + K A++ E K LL F + +L K E + + G
Sbjct: 550 RFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYN-------------PGL 596
Query: 401 DGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLK 460
+ E++++ +K S K+IE +++E++K+ D E ER + E +++E ++++
Sbjct: 597 EFERQQREELEKLESKRKLIE---EMEEKQKS-----DKAELERMQQEVETQRKETEIVQ 648
Query: 461 AQ--QEHQSLLEKLSALEKKVIVGGVDLLAKAE--EQEKLLEESNMELEERRKRAEQLRR 516
Q ++ +SL + +E K+ DLLA+ E E+E+L E+ +EL+++R+ E R
Sbjct: 649 LQIRKQEESLKRRSFHIENKL----KDLLAEKEKFEEERLREQQEIELQKKRQEEETFLR 704
Query: 517 ELEE----KEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIE 572
EE KE + EK+ QE Q + +K + + L K + + ++E +
Sbjct: 705 VQEELQRLKELNNNEKAEKFQIFQELDQLQKEK-DEQYAKLELEKKRLEEQEKEQVMLVA 763
Query: 573 GLLENIRQLSRELRL 587
L E +R+ ++L
Sbjct: 764 HLEEQLREKQEMIQL 778
Score = 44.7 bits (104), Expect = 3e-04
Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 27/196 (13%)
Query: 361 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMI 420
RQ ++E+E+L+ K + EE+ S E + + EV ++ + + + + + +
Sbjct: 600 RQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLK 659
Query: 421 EMQAKIDEERKALETKLDMEEEERNKARAELE-----KREKDLLKAQQEHQSL--LEKLS 473
I+ + K L + + EEER + + E+E + E+ L+ Q+E Q L L
Sbjct: 660 RRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNE 719
Query: 474 ALEKKVIVGGVDLL--------AKAEEQEKLLEESNME-----------LEERRKRAEQL 514
EK I +D L AK E ++K LEE E L E+++ + L
Sbjct: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLL 779
Query: 515 RR-ELEEKEQERLDIE 529
RR E++ E+E+ D+E
Sbjct: 780 RRGEVQWVEEEKRDLE 795
Score = 41.6 bits (96), Expect = 0.003
Identities = 72/339 (21%), Positives = 145/339 (42%), Gaps = 43/339 (12%)
Query: 343 KNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDG 402
+ ++ +N + K + FQ E+++L+K E+ E+ + ++ ++ E+ +V
Sbjct: 707 EELQRLKELNNNEKAEKFQIFQ-ELDQLQK--EKDEQYAKLELEKKRLEEQEKEQVMLVA 763
Query: 403 EKRKKRRGKKKVSPDKMIEMQAK-----IDEERKALE---TKLDMEEEERNKARAELEKR 454
++ R K++ MI++ + ++EE++ LE L +E R + E+
Sbjct: 764 HLEEQLREKQE-----MIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEEL 818
Query: 455 EKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQL 514
EK L+ + + L KL LEK ++ L + +E++++LE E
Sbjct: 819 EKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCE----------- 867
Query: 515 RRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGL 574
+KE L+ ++ + E +K+K V L + ++ L Q H + L
Sbjct: 868 ----HDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNH---LPTL 920
Query: 575 LENIRQLSRELRLQMLIIDNF---IPRDYQEMIENYVHWNEDIGEWQ-LKCVAYTGNNMR 630
LE ++ L L +DN + ++ +E E + + + Q L+ N+
Sbjct: 921 LEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIA 980
Query: 631 KQTPVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLER 669
+Q KKEK+ E E+L ++L +LER
Sbjct: 981 RQEEKVRKKEKEILESREKQ-----QREALERALARLER 1014
Score = 36.2 bits (82), Expect = 0.11
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 28/178 (15%)
Query: 397 EVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREK 456
+V ++ E+++++ + + + +++ ++QA + EE+ R K + LE REK
Sbjct: 944 QVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIAR----QEEKVRKKEKEILESREK 999
Query: 457 DLLKAQQEHQSLLEKL-SALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLR 515
+A + + LE+ SAL++ +G ME+EE+R++ L
Sbjct: 1000 QQREALERALARLERRHSALQRHSTLG-------------------MEIEEQRQKLASLN 1040
Query: 516 RELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEG 573
E+ + +E + +L+++ + +L+ L E+ +Q++H +EG
Sbjct: 1041 SGSREQSGLQASLEAEQEALEKDQE----RLEYEIQQLKQKIYEVDGVQKDHHGTLEG 1094
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 301 bits (772), Expect = 1e-81
Identities = 208/574 (36%), Positives = 309/574 (53%), Gaps = 46/574 (8%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGT--ITVHKTDSSNE-PPKTFTFDTVFGPE 70
++KV+ R RPLN+ E +RG I + + D S K + FD VF P
Sbjct: 9 SIKVLCRFRPLNQAEI------------LRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPN 56
Query: 71 SKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHI 130
+ Q VY+ A I+ VL GYNGTIFAYGQT +GKT TMEG P+L GIIP I
Sbjct: 57 TTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDI 116
Query: 131 FGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVN 190
F HI + + F ++VSY EIY +++RDLL +T L V E + ++K + V+
Sbjct: 117 FNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTN-LSVHEDKNRVPFVKGCTERFVS 175
Query: 191 NADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVD 250
+ +++ ++ G NR V TNMNEHSSRSH+IF I I+ + + GKL+LVD
Sbjct: 176 SPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLS---GKLYLVD 232
Query: 251 LAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSL 310
LAGSE+ +KTGA G L EA IN SLS LGNVISAL +G ++VPYR+SK+TR+LQDSL
Sbjct: 233 LAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSL 292
Query: 311 GGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN-EDPKDALLRQFQKEIEE 369
GGN +T M P+ YN ET STL + RAK IKN A +N E + ++++KE E+
Sbjct: 293 GGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEK 352
Query: 370 LKKKLEEGEEI--------SGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIE 421
K + E ++ +G ++ +E EE +G + + + E
Sbjct: 353 TKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPE 412
Query: 422 MQAKIDEERKALETKLDMEEEERNKARAELEKREKDLL--------------KAQQEHQS 467
+ K +EE + L +LD +++E N+ +EK ++ +L K Q+E
Sbjct: 413 ERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSH 472
Query: 468 LLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLD 527
L + A + +V ++L EE ++ + E+EE+ ++ + L EL +K L
Sbjct: 473 LQSENDAAKDEV----KEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLS 528
Query: 528 IEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMA 561
+E + LQE + + K++ +V LM SE +
Sbjct: 529 LESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFS 562
Score = 42.4 bits (98), Expect = 0.001
Identities = 73/332 (21%), Positives = 138/332 (41%), Gaps = 39/332 (11%)
Query: 359 LLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSP-- 416
+L K++ E + GE +ISG+ E++ + K + + K+
Sbjct: 550 VLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLE 609
Query: 417 DKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKA---QQEHQSLLEKLS 473
+ +E K++ + L + + + K R+ E + LK ++ + SL ++L+
Sbjct: 610 NLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELA 669
Query: 474 ALEKKVIVGGVDLLAK------AEEQEKLLE-ESNMELEERRKRAEQLRRELEEKEQ--- 523
L+ + V V L K A+E +K LE + E ++ +LR E+ EK++
Sbjct: 670 KLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTID 729
Query: 524 ERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQ---REIEGLLENI-R 579
E D+ +K E+ Q +KLK E+ L + H+ ++++GL E + R
Sbjct: 730 ELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVAR 789
Query: 580 QLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIG--EWQLKCVAYTGNNMRKQTPVPD 637
+L L+ L + + R + ++ ED G Q + +++ NN+ + T V
Sbjct: 790 ELQTLHNLRKLFVQDVTTR----VKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKV-- 843
Query: 638 KKEKDPFEVDLSHVYLAYTEESLRQSLMKLER 669
H L LR L KLE+
Sbjct: 844 ------------HKQLVRDNADLRCELPKLEK 863
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 301 bits (771), Expect = 1e-81
Identities = 233/617 (37%), Positives = 335/617 (54%), Gaps = 58/617 (9%)
Query: 13 DNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGT-ITVHKTDSSNEPPKTFTFDTVFGPES 71
D +KV VR RP ER S +Q + + + T + +H SN PKTFTFD V ++
Sbjct: 25 DAIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLH----SNPEPKTFTFDHVADVDT 80
Query: 72 KQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPE----LRGIIPNSF 127
Q V+ A+ I++S + GYNGTIFAYGQTG+GKTFTM G LRG+IP SF
Sbjct: 81 TQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRSF 140
Query: 128 AHIFGHI----AKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKD 183
++F I KA FL + S++EIYNE++ DLL + L ++E GV++
Sbjct: 141 EYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDS-ASAGLYLREHIKKGVFVVG 199
Query: 184 LSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRM 243
VV +A + ++++ G +NR V +T+MN SSRSHA+FTITIE EK + +++R
Sbjct: 200 AVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNE-IVNIRT 258
Query: 244 GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD---GKSTHVPYRNS 300
L+LVDLAGSERQ T A G RLKEA IN SLS LG VI+ALVD GK HV YR+S
Sbjct: 259 SLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCYRDS 318
Query: 301 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 360
KLT LL+DSLGGN+KT + AN+ P + ET+STL +A RAK IKNKA +NED + +
Sbjct: 319 KLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQ-GNV 377
Query: 361 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMI 420
Q Q E++ LK++L E SG S D KK+ + + M+
Sbjct: 378 SQLQAEVKRLKEQL--AELASGQTPPESFLTRD------------KKKTNYMEYFQEAML 423
Query: 421 EMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI 480
+ K ++E+K+L K+ E+ K + + + K ++K +++ LEKL K
Sbjct: 424 FFK-KSEQEKKSLIEKVTQLEDLTLK-KEKFIQSNKMIVKFREDQIIRLEKL----HKES 477
Query: 481 VGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELE--------EKEQERLDIEEKY 532
GG EEQ++LL E E++ R++ E R + +E RL + E
Sbjct: 478 RGGF----LPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPV 533
Query: 533 TSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQE----HQREIEGLLENIRQLSRELRLQ 588
QE KL+K ++ + + E +D Q+ ++ L N +L +L LQ
Sbjct: 534 KRAQEMDAQTIAKLEKAFSEI--SGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQL-LQ 590
Query: 589 MLIIDNFIPRDYQEMIE 605
+ N ++Y+E E
Sbjct: 591 IQTELNNSKQEYEEFKE 607
Score = 50.4 bits (119), Expect = 5e-06
Identities = 77/371 (20%), Positives = 158/371 (42%), Gaps = 59/371 (15%)
Query: 246 LHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRL 305
L +++ E+Q +T Q++ + K+ SL VIS+L + + + K+
Sbjct: 932 LKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDS-----DKKVVAD 986
Query: 306 LQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIK-NKARINEDPKDALLRQFQ 364
L + + +T +C ETI TL+ + N K N A ++ + L+++ +
Sbjct: 987 LMNQI-QELRTSVCEK--------TETIDTLKQELKDINCKYNSALVDREESRVLIKKQE 1037
Query: 365 KEIEELKKKLEEGEEISGSDISGS---EEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIE 421
+I +LK+ L I DI E+ ++ E KK G + + +++ +
Sbjct: 1038 VDILDLKETLR--LRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTK 1095
Query: 422 MQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQS----------LLEK 471
+A I E + L K + E+++N+ ++ + E + A ++ QS L +
Sbjct: 1096 KEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKL 1155
Query: 472 LSALEKKVIVGGVD------LLAKAEE------------QEKLLEESNMELEER------ 507
L E+++ G L+ K E +E+L E N+ LE +
Sbjct: 1156 LETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKN 1215
Query: 508 ---RKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQ 564
+ + + ++R+ E +Q D ++ +E + + K K V ML K+++ ++Q
Sbjct: 1216 WLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEML-KMKADLEEVQ 1274
Query: 565 QE-HQREIEGL 574
+ +E+E L
Sbjct: 1275 SALYNKEMECL 1285
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/335 (20%), Positives = 153/335 (45%), Gaps = 51/335 (15%)
Query: 285 SALVDGKSTHVPYRNSKLT----------RLLQDSLGGNSKTMMCANIGPADYNYDETIS 334
SALVD + + V + ++ R+L + + + M+C ++ A E ++
Sbjct: 1021 SALVDREESRVLIKKQEVDILDLKETLRLRILSEDI---ERDMLCEDLAHAT----EQLN 1073
Query: 335 TLRYANRAKN-IKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDD 393
L A++ + + A+ K+AL+++ Q ++ + K+++E+ + + E D
Sbjct: 1074 MLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMD 1133
Query: 394 EEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKA-------LETKLDMEEEERNK 446
E + K + K++E Q + E+ +A L TKL+ + E +N
Sbjct: 1134 SAAE----DPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNA 1189
Query: 447 ARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEE 506
++++ +++ + E Q L+EK L+ G +D + + +E N +L+
Sbjct: 1190 EILRMKEQLREMENLRLESQQLIEKNWLLQ-----GQLDDIKRQKENSDQNHPDNQQLKN 1244
Query: 507 RRKRA--EQLRRE--LEEKEQERLDIEEKYTSL---QEEAQGKTKKLKKVWTMLMAA--- 556
++ + E+L + +EE + + D+EE ++L + E T ++++ T+ A
Sbjct: 1245 EQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQE 1304
Query: 557 ----KSEMADLQQEHQR---EIEGLLENIRQLSRE 584
+S++ ++ +E +R E+E L + + L+ E
Sbjct: 1305 KEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEE 1339
Score = 43.9 bits (102), Expect = 5e-04
Identities = 45/211 (21%), Positives = 95/211 (45%), Gaps = 38/211 (18%)
Query: 350 RINEDP--KDALLRQFQKEIEELKKKLEEGEEISGS---------DISGSEEDDDEEGEV 398
++NED K+A + + ++++ E++ E +++ DI +E+ D+
Sbjct: 1179 KLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPD 1238
Query: 399 GEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDL 458
+ + ++ K++++ K++E + L+ K D+EE ++ L +E +
Sbjct: 1239 NQQLKNEQEESIKERLAKSKIVE---------EMLKMKADLEE-----VQSALYNKEMEC 1284
Query: 459 LKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRE- 517
L+ E +E+ LE K L +K EE + E ++ E+E RK+ E L E
Sbjct: 1285 LRMTDE----VERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEEN 1340
Query: 518 --------LEEKEQERLDIEEKYTSLQEEAQ 540
L +K Q + ++++ L EE +
Sbjct: 1341 GKLVGHQNLHQKIQYVVRLKKENVRLAEETE 1371
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/147 (21%), Positives = 73/147 (49%), Gaps = 10/147 (6%)
Query: 426 IDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVD 485
+ E+ AL+ KLD EE + K + ++K E + Q+ S E++ +++ +
Sbjct: 722 VQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSS--ERIDWTKQQE-----E 774
Query: 486 LLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKK 545
LL++ EK L+E+ + + + LR L ++E ++ +Y+S + + K+
Sbjct: 775 LLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQE---KE 831
Query: 546 LKKVWTMLMAAKSEMADLQQEHQREIE 572
K+ M + ++ +L+ E+++ +E
Sbjct: 832 FNKLSERHMHVQLQLDNLRLENEKLLE 858
Score = 39.7 bits (91), Expect = 0.010
Identities = 51/244 (20%), Positives = 107/244 (43%), Gaps = 24/244 (9%)
Query: 351 INEDPKDAL---LRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKK 407
+NE +A+ LR Q+++ L+ KL+E E ++ + D E + E
Sbjct: 707 MNEQAFEAISEELRTVQEQMSALQAKLDEEEH---KNLKLQQHVDKLEHHSTQMQELFSS 763
Query: 408 RRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQS 467
R ++++ ++++ + +TK D + E + R L +K+L + E+ S
Sbjct: 764 ERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSS 823
Query: 468 LL----EKLSALEKKVIVGGVDLLAKAEEQEKLLE------ESNMELEERRK-RAEQLRR 516
++ + L ++ + + L E EKLLE +S L+E K +QL R
Sbjct: 824 FKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSR 883
Query: 517 ELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLE 576
L+ ++E ++ +L E + + ++ K+ + + ++ +EI +LE
Sbjct: 884 NLQNFKKENETLKSDLNNLMELLEAEKERNNKL-------SLQFEEDKENSSKEILKVLE 936
Query: 577 NIRQ 580
+RQ
Sbjct: 937 AVRQ 940
Score = 33.5 bits (75), Expect = 0.69
Identities = 50/245 (20%), Positives = 95/245 (38%), Gaps = 32/245 (13%)
Query: 354 DPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKK 413
+ +D LL + + EI+ L++++E ++ + E+ R++ R +
Sbjct: 484 EEQDRLLSELRNEIQTLREQIEHHPRVAKYAM--------------ENHSLREENRRLRL 529
Query: 414 VSPDKMI-EMQAK-IDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEK 471
+ P K EM A+ I + KA ME+ ++N+ + +++ L A E K
Sbjct: 530 LEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTE------K 583
Query: 472 LSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEK 531
L A LL E +E E RKR +L EL+ ++ L++E
Sbjct: 584 LKA----------QLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENL 633
Query: 532 YTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLI 591
+ + + + +L K+ + + Q H R + L + I
Sbjct: 634 LEATKACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSI 693
Query: 592 IDNFI 596
+DN I
Sbjct: 694 LDNDI 698
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 301 bits (770), Expect = 2e-81
Identities = 240/710 (33%), Positives = 357/710 (50%), Gaps = 83/710 (11%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
V+V +RCRPL +E S + +S + V TD K+FT+D VF P ++Q
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVG-TD------KSFTYDFVFDPCTEQE 62
Query: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR----GIIPNSFAHI 130
+V+N P+I + +GYN T+ AYGQTG+GKT++M G + GIIP +
Sbjct: 63 EVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLL 122
Query: 131 FGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQ-RLEVKERPDVGVYIKDLSAYVV 189
F I K + D F ++VSYLEIYNEE+ DLL + + ++ ++E P G+ I L+ V
Sbjct: 123 FKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
Query: 190 NNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLV 249
A D + G+ +R+V +T MN SSRSHAIFTI+IE +K D N R KLHLV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS-DKNCSFR-SKLHLV 239
Query: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKS-THVPYRNSKLTRLLQD 308
DLAGSERQ KT A G RLKE IN L LGNVISAL D K + VPYR+SKLTRLLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299
Query: 309 SLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIE 368
SLGGNS T+M A + PAD N +ET+STLRYA+RA+ IKNK +N DP A L +++++
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQ 359
Query: 369 ELKKKLEEGEEISGSDISGSEEDDDEEG---------EVGEDGEKRKKRRGKKKVSPDKM 419
+L+ L + G + GS + E + E+ EK + K +M
Sbjct: 360 QLQVLLLQAH---GGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQM 416
Query: 420 IE-----------MQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSL 468
+E + AK++E R+ + KLD+++ EL++ + + QQ L
Sbjct: 417 LERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQL 476
Query: 469 LEKLSALEKKVIVGGVDLLAKAEEQEKLLEESN-----------------MELEERRKRA 511
++ A I V+ A+ E + S+ +EL
Sbjct: 477 SDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALK 536
Query: 512 EQLRRELEEKEQERLDIEEKY----TSLQEEAQGKTKKLKKVWTMLMAAKSEM--ADLQQ 565
E L R++ + + + I+ +Y +L+ E K+ +++ L AK + A L +
Sbjct: 537 EALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSE 596
Query: 566 EHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYV-HWNEDIGEWQLKCVAY 624
+ ++ L I L ++L Q ++ +E E V N++I W +K
Sbjct: 597 HRHKLLQELEGQIADLKKKLNEQSKLL------KLKESTERTVSKLNQEI--WMMK---- 644
Query: 625 TGNNMRKQTPVPDKKEKDPF-----EVDLSHVYLAYTEESLRQSLMKLER 669
N R Q K++ + F + D + L + + L+KLER
Sbjct: 645 ---NQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLER 691
Score = 47.8 bits (112), Expect = 4e-05
Identities = 59/266 (22%), Positives = 111/266 (41%), Gaps = 39/266 (14%)
Query: 336 LRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEE 395
+R AK N+A+++E + LL++ + +I +LKKKL E ++ S
Sbjct: 579 VRELQTAKKNVNQAKLSEH-RHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLN 637
Query: 396 GEVG--------------EDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEE 441
E+ ED EK ++ + KK ++ E K E LE +
Sbjct: 638 QEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQS 697
Query: 442 E---ERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGV--------DLLAKA 490
+ + A KR KD L+ Q+E ++ + K+ I V +++
Sbjct: 698 SVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVST 757
Query: 491 EEQEKLLEESNMELEERRKRAEQLRRELEEKEQER----------LDIEEKYTSLQEEAQ 540
EE ++ L + LE+R+ A+ + + E+KE + E + + E
Sbjct: 758 EEAKRHLNDL---LEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESED 814
Query: 541 GKTKKLKKVWTMLMAAKSEMADLQQE 566
TK+++ + T + +++ADLQQ+
Sbjct: 815 CITKQIESLETEMELRSAQIADLQQK 840
Score = 41.2 bits (95), Expect = 0.003
Identities = 59/272 (21%), Positives = 121/272 (44%), Gaps = 35/272 (12%)
Query: 418 KMIEMQAKIDEERKALET-KLDMEE----EERNKARAELEKREKDLLKAQQEHQSLLEKL 472
++I +Q + +E + L+T K ++ + E R+K ELE + DL K E LL+
Sbjct: 567 EVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLK 626
Query: 473 SALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERR-------KRAEQLRRELEEKEQER 525
+ E+ V ++ ++ +L+ + + E+ R K QL+ +++ E
Sbjct: 627 ESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYEL 686
Query: 526 LDIE---EKYTSL----QEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQRE-IEGLLEN 577
L +E +K +S+ EEA K+LK + + E+ D ++E Q EG+
Sbjct: 687 LKLERNFQKQSSVLRRKTEEAAAANKRLKDA----LQKQREVTDKRKETQSHGKEGIAAR 742
Query: 578 IRQ-LSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVP 636
+R L E +++++ R +++E+ +D+ + + K ++ P P
Sbjct: 743 VRNWLGNE--IEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEK-------KESRENP-P 792
Query: 637 DKKEKDPFEVDLSHVYLAYTEESLRQSLMKLE 668
K K F + H + +E+ + + + LE
Sbjct: 793 PKLRKCTFSLSEVHGQVLESEDCITKQIESLE 824
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 300 bits (769), Expect = 2e-81
Identities = 181/402 (45%), Positives = 250/402 (62%), Gaps = 28/402 (6%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSN------EPPKTFTFDTVFG 68
VKV VR RP+N RE + K V EM G TV SN +PPK F FD F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVV---EMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 69 PESK--------QLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
+ Q V+ I++ +GYN IFAYGQTG+GK+F+M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---EQL 119
Query: 121 GIIPNSFAHIFGHIAKAEGDTR-FLVRVSYLEIYNEEVRDLLG-KDQTQRLEVKERPDVG 178
G+IP +F I+ + +++ F V VSY+EIYNE+VRDLL K Q L+V+E +G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 179 VYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGID-G 237
Y+ LS V + +D++ +M+ G+K+R+V ATNMNE SSRSHA+F I I + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 238 NMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKS 292
N ++ K+ LVDLAGSER +KTGA G+RLKE + IN SL+TLG VIS+L D GKS
Sbjct: 240 NSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKS 299
Query: 293 THVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN 352
VPYR+S LT LL+D+LGGNS+T M A I PA NY+ET+STLRYA+RAK I N A +N
Sbjct: 300 KFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVN 359
Query: 353 EDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDE 394
EDP ++R+ ++E+E+L+++L + E + ++ E+ ++
Sbjct: 360 EDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEK 401
Score = 35.0 bits (79), Expect = 0.24
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 410 GKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLL 469
G + S I A EE + D + N A + K + + ++E + L
Sbjct: 319 GNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLR 378
Query: 470 EKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIE 529
E+LS E + +L K EE EKL++E + EE+ ++ E++ +E +++ E + I
Sbjct: 379 EQLSQAEA---MKAPELKEKLEESEKLIKELTVTWEEKLRKTEEIAQE-RQRQLESMGIS 434
Query: 530 EKYTSLQ 536
+ + ++
Sbjct: 435 LEMSGIK 441
Score = 34.3 bits (77), Expect = 0.40
Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 24/164 (14%)
Query: 429 ERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLA 488
E++ LE K EE+R ELE+ + L +Q S ++L+ + +
Sbjct: 606 EKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQ---TAQQKVTQ 662
Query: 489 KAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKK 548
AEE+++L +S +L E+ +A L RE +E + + +LQ A + K+
Sbjct: 663 WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANRKR 722
Query: 549 -------------------VWTM--LMAAKSEMADLQQEHQREI 571
VWT+ L +M DL QE + ++
Sbjct: 723 GAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKV 766
Score = 29.6 bits (65), Expect = 9.9
Identities = 18/89 (20%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Query: 487 LAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE-KYTSLQEEAQGKTKK 545
L A+ ++++ + + + K +LR E+E+ ++ E K L+E+ + K
Sbjct: 343 LRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKL 402
Query: 546 LKKVWTMLMAAKSEMADLQQEHQREIEGL 574
+K++ + ++ QE QR++E +
Sbjct: 403 IKELTVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 300 bits (769), Expect = 2e-81
Identities = 181/402 (45%), Positives = 250/402 (62%), Gaps = 28/402 (6%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSN------EPPKTFTFDTVFG 68
VKV VR RP+N RE + K V EM G TV SN +PPK F FD F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVV---EMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 69 PESK--------QLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
+ Q V+ I++ +GYN IFAYGQTG+GK+F+M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---EQL 119
Query: 121 GIIPNSFAHIFGHIAKAEGDTR-FLVRVSYLEIYNEEVRDLLG-KDQTQRLEVKERPDVG 178
G+IP +F I+ + +++ F V VSY+EIYNE+VRDLL K Q L+V+E +G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 179 VYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGID-G 237
Y+ LS V + +D++ +M+ G+K+R+V ATNMNE SSRSHA+F I I + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 238 NMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKS 292
N ++ K+ LVDLAGSER +KTGA G+RLKE + IN SL+TLG VIS+L D GKS
Sbjct: 240 NSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKS 299
Query: 293 THVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN 352
VPYR+S LT LL+D+LGGNS+T M A I PA NY+ET+STLRYA+RAK I N A +N
Sbjct: 300 KFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVN 359
Query: 353 EDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDE 394
EDP ++R+ ++E+E+L+++L + E + ++ E+ ++
Sbjct: 360 EDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEK 401
Score = 35.0 bits (79), Expect = 0.24
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 410 GKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLL 469
G + S I A EE + D + N A + K + + ++E + L
Sbjct: 319 GNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLR 378
Query: 470 EKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIE 529
E+LS E + +L K EE EKL++E + EE+ ++ E++ +E +++ E + I
Sbjct: 379 EQLSQAEA---MKAPELKEKLEESEKLIKELTVTWEEKLRKTEEIAQE-RQRQLESMGIS 434
Query: 530 EKYTSLQ 536
+ + ++
Sbjct: 435 LEMSGIK 441
Score = 34.3 bits (77), Expect = 0.40
Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 24/164 (14%)
Query: 429 ERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLA 488
E++ LE K EE+R ELE+ + L +Q S ++L+ + +
Sbjct: 606 EKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQ---TAQQKVTQ 662
Query: 489 KAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKK 548
AEE+++L +S +L E+ +A L RE +E + + +LQ A + K+
Sbjct: 663 WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANRKR 722
Query: 549 -------------------VWTM--LMAAKSEMADLQQEHQREI 571
VWT+ L +M DL QE + ++
Sbjct: 723 GAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKV 766
Score = 29.6 bits (65), Expect = 9.9
Identities = 18/89 (20%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Query: 487 LAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE-KYTSLQEEAQGKTKK 545
L A+ ++++ + + + K +LR E+E+ ++ E K L+E+ + K
Sbjct: 343 LRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKL 402
Query: 546 LKKVWTMLMAAKSEMADLQQEHQREIEGL 574
+K++ + ++ QE QR++E +
Sbjct: 403 IKELTVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 300 bits (769), Expect = 2e-81
Identities = 181/402 (45%), Positives = 250/402 (62%), Gaps = 28/402 (6%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSN------EPPKTFTFDTVFG 68
VKV VR RP+N RE + K V EM G TV SN +PPK F FD F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVV---EMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 69 PESK--------QLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
+ Q V+ I++ +GYN IFAYGQTG+GK+F+M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---EQL 119
Query: 121 GIIPNSFAHIFGHIAKAEGDTR-FLVRVSYLEIYNEEVRDLLG-KDQTQRLEVKERPDVG 178
G+IP +F I+ + +++ F V VSY+EIYNE+VRDLL K Q L+V+E +G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 179 VYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGID-G 237
Y+ LS V + +D++ +M+ G+K+R+V ATNMNE SSRSHA+F I I + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 238 NMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKS 292
N ++ K+ LVDLAGSER +KTGA G+RLKE + IN SL+TLG VIS+L D GKS
Sbjct: 240 NSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKS 299
Query: 293 THVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN 352
VPYR+S LT LL+D+LGGNS+T M A I PA NY+ET+STLRYA+RAK I N A +N
Sbjct: 300 KFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVN 359
Query: 353 EDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDE 394
EDP ++R+ ++E+E+L+++L + E + ++ E+ ++
Sbjct: 360 EDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEK 401
Score = 35.0 bits (79), Expect = 0.24
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 410 GKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLL 469
G + S I A EE + D + N A + K + + ++E + L
Sbjct: 319 GNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLR 378
Query: 470 EKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIE 529
E+LS E + +L K EE EKL++E + EE+ ++ E++ +E +++ E + I
Sbjct: 379 EQLSQAEA---MKAPELKEKLEESEKLIKELTVTWEEKLRKTEEIAQE-RQRQLESMGIS 434
Query: 530 EKYTSLQ 536
+ + ++
Sbjct: 435 LEMSGIK 441
Score = 34.3 bits (77), Expect = 0.40
Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 24/164 (14%)
Query: 429 ERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLA 488
E++ LE K EE+R ELE+ + L +Q S ++L+ + +
Sbjct: 606 EKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQ---TAQQKVTQ 662
Query: 489 KAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKK 548
AEE+++L +S +L E+ +A L RE +E + + +LQ A + K+
Sbjct: 663 WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANRKR 722
Query: 549 -------------------VWTM--LMAAKSEMADLQQEHQREI 571
VWT+ L +M DL QE + ++
Sbjct: 723 GAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKV 766
Score = 29.6 bits (65), Expect = 9.9
Identities = 18/89 (20%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Query: 487 LAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE-KYTSLQEEAQGKTKK 545
L A+ ++++ + + + K +LR E+E+ ++ E K L+E+ + K
Sbjct: 343 LRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKL 402
Query: 546 LKKVWTMLMAAKSEMADLQQEHQREIEGL 574
+K++ + ++ QE QR++E +
Sbjct: 403 IKELTVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 300 bits (769), Expect = 2e-81
Identities = 181/402 (45%), Positives = 250/402 (62%), Gaps = 28/402 (6%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSN------EPPKTFTFDTVFG 68
VKV VR RP+N RE + K V EM G TV SN +PPK F FD F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVV---EMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 69 PESK--------QLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
+ Q V+ I++ +GYN IFAYGQTG+GK+F+M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---EQL 119
Query: 121 GIIPNSFAHIFGHIAKAEGDTR-FLVRVSYLEIYNEEVRDLLG-KDQTQRLEVKERPDVG 178
G+IP +F I+ + +++ F V VSY+EIYNE+VRDLL K Q L+V+E +G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 179 VYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGID-G 237
Y+ LS V + +D++ +M+ G+K+R+V ATNMNE SSRSHA+F I I + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 238 NMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKS 292
N ++ K+ LVDLAGSER +KTGA G+RLKE + IN SL+TLG VIS+L D GKS
Sbjct: 240 NSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKS 299
Query: 293 THVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN 352
VPYR+S LT LL+D+LGGNS+T M A I PA NY+ET+STLRYA+RAK I N A +N
Sbjct: 300 KFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVN 359
Query: 353 EDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDE 394
EDP ++R+ ++E+E+L+++L + E + ++ E+ ++
Sbjct: 360 EDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEK 401
Score = 35.0 bits (79), Expect = 0.24
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 410 GKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLL 469
G + S I A EE + D + N A + K + + ++E + L
Sbjct: 319 GNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLR 378
Query: 470 EKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIE 529
E+LS E + +L K EE EKL++E + EE+ ++ E++ +E +++ E + I
Sbjct: 379 EQLSQAEA---MKAPELKEKLEESEKLIKELTVTWEEKLRKTEEIAQE-RQRQLESMGIS 434
Query: 530 EKYTSLQ 536
+ + ++
Sbjct: 435 LEMSGIK 441
Score = 34.3 bits (77), Expect = 0.40
Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 24/164 (14%)
Query: 429 ERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLA 488
E++ LE K EE+R ELE+ + L +Q S ++L+ + +
Sbjct: 606 EKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQ---TAQQKVTQ 662
Query: 489 KAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKK 548
AEE+++L +S +L E+ +A L RE +E + + +LQ A + K+
Sbjct: 663 WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANRKR 722
Query: 549 -------------------VWTM--LMAAKSEMADLQQEHQREI 571
VWT+ L +M DL QE + ++
Sbjct: 723 GAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKV 766
Score = 29.6 bits (65), Expect = 9.9
Identities = 18/89 (20%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Query: 487 LAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE-KYTSLQEEAQGKTKK 545
L A+ ++++ + + + K +LR E+E+ ++ E K L+E+ + K
Sbjct: 343 LRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKL 402
Query: 546 LKKVWTMLMAAKSEMADLQQEHQREIEGL 574
+K++ + ++ QE QR++E +
Sbjct: 403 IKELTVTWEEKLRKTEEIAQERQRQLESM 431
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 300 bits (768), Expect = 3e-81
Identities = 205/574 (35%), Positives = 309/574 (53%), Gaps = 32/574 (5%)
Query: 9 PESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFG 68
P C ++KV+ R RPLNE E + + + +G TV K + FD V
Sbjct: 4 PAEC-SIKVMCRFRPLNEAE---ILRGDKFIPKFKGDETVVIGQG-----KPYVFDRVLP 54
Query: 69 PESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFA 128
P + Q VYN A+ I+ VLEGYNGTIFAYGQT +GKT TMEG P+L GIIP
Sbjct: 55 PNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAH 114
Query: 129 HIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYV 188
IF HI + + F ++VSY EIY +++RDLL +T L V E + Y+K +
Sbjct: 115 DIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN-LAVHEDKNRVPYVKGCTERF 173
Query: 189 VNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHL 248
V++ +++ ++ G NR V TNMNEHSSRSH+IF I I+ + + GKL+L
Sbjct: 174 VSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS---GKLYL 230
Query: 249 VDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQD 308
VDLAGSE+ +KTGA G L EA IN SLS LGNVISAL +G THVPYR+SK+TR+LQD
Sbjct: 231 VDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQD 290
Query: 309 SLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN-EDPKDALLRQFQKEI 367
SLGGN +T + P+ +N ET STL + RAK IKN +N E + ++++KE
Sbjct: 291 SLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEK 350
Query: 368 EELKK--------KLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKM 419
E+ K ++E +G + E+ ++ + E + V
Sbjct: 351 EKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGIS 410
Query: 420 IEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLL-------KAQQEHQSLLEKL 472
E + K DEE +L +LD +++E N+ EK ++ +L +++++ + E+L
Sbjct: 411 TEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEEL 470
Query: 473 SAL--EKKVIVGGV-DLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIE 529
+ L E + V ++L EE ++ + E+E++ + EQL EL +K +
Sbjct: 471 TRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQ 530
Query: 530 EKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADL 563
+ + LQE + + K+ ++ +L+ E+ +
Sbjct: 531 RELSQLQELSNHQKKRATEILNLLLKDLGEIGGI 564
Score = 41.2 bits (95), Expect = 0.003
Identities = 79/368 (21%), Positives = 153/368 (41%), Gaps = 54/368 (14%)
Query: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDS 309
D E + KT A Q E + +L+T +S L + S H R +++ LL
Sbjct: 499 DQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQE-LSNHQKKRATEILNLLLKD 557
Query: 310 LG------GNSKTMMCANIGPADYNYDETISTL---RYANRAKNIKNKARINEDPKDALL 360
LG G + A++ + T++ L + + K++ N+++ E +
Sbjct: 558 LGEIGGIIGTNDVKTLADVNGV-IEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSN 616
Query: 361 RQFQKEIEELKK-----KLEEGEEISGSDISGSEEDDDEEGEVGEDG--EKRKKRRGKKK 413
R+ EL E + S +D + E + E +D E+ K R ++K
Sbjct: 617 RKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEK 676
Query: 414 VSP----DKMIEMQAKI---DEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQ 466
+ DK E ++ +E +KALE +++ E K + L +E Q
Sbjct: 677 MHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDE-------IEEKQ 729
Query: 467 SLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESN---MELEERRKRAEQLRRELEEKEQ 523
+++++ L +K+ + EQEKL + N +E +ER + E+L +++EQ
Sbjct: 730 KIIDEIRDLNQKLQL----------EQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQ 779
Query: 524 ERLDIEEKYTSLQEEAQGKTKKLKKVWTM-LMAAKSEMADLQQE-------HQREIEGLL 575
R D++ ++ E Q L+K++ L + +L + +++I L
Sbjct: 780 AREDLKGLEETVSRELQ-TLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLE 838
Query: 576 ENIRQLSR 583
N+ QL++
Sbjct: 839 NNLEQLTK 846
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 300 bits (768), Expect = 3e-81
Identities = 178/400 (44%), Positives = 244/400 (61%), Gaps = 23/400 (5%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEP----PKTFTFDTVFGPE 70
VKV VR RP+N RE + K V VD + + T+ S PK F +D F
Sbjct: 6 VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSM 65
Query: 71 SKQLD--------VYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGI 122
+ + V+ I+ + +GYN IFAYGQTG+GK++TM G P G+
Sbjct: 66 DESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP---GL 122
Query: 123 IPNSFAHIFGHIAKAEGDTR-FLVRVSYLEIYNEEVRDLLG-KDQTQRLEVKERPDVGVY 180
IP + +F K E + + F V VSY+EIYNE+VRDLL K Q L+V+E +G Y
Sbjct: 123 IPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGPY 182
Query: 181 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGI-DGNM 239
+ LS V + D++ +M+ G+K+R+V ATNMNE SSRSHA+F IT+ + + G
Sbjct: 183 VDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTS 242
Query: 240 HVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKSTH 294
++GKL LVDLAGSER KTGA G RLKE + IN SL+TLG VISAL D K+
Sbjct: 243 GEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKNKF 302
Query: 295 VPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINED 354
VPYR+S LT LL+DSLGGNSKT M A + PA NYDET+STLRYA+RAK+I N A +NED
Sbjct: 303 VPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVNED 362
Query: 355 PKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDE 394
P ++R ++E+E+L+++L + E + ++ E+ ++
Sbjct: 363 PNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEK 402
Score = 32.3 bits (72), Expect = 1.5
Identities = 20/67 (29%), Positives = 39/67 (58%), Gaps = 4/67 (5%)
Query: 462 QQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK 521
++E + L E+L+ E + +L + EE EKL++E + EE+ ++ E++ +E +K
Sbjct: 372 REEVEKLREQLTKAEA---MKSPELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQE-RQK 427
Query: 522 EQERLDI 528
+ E L I
Sbjct: 428 QLESLGI 434
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 299 bits (766), Expect = 5e-81
Identities = 219/624 (35%), Positives = 327/624 (52%), Gaps = 56/624 (8%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
V+V +RCRPL +E S + +S + V TD K+FT+D VF P ++Q
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVG-TD------KSFTYDFVFDPSTEQE 62
Query: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR----GIIPNSFAHI 130
+V+N P+I V +GYN T+ AYGQTG+GKT++M G + G+IP +
Sbjct: 63 EVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLL 122
Query: 131 FGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQ-RLEVKERPDVGVYIKDLSAYVV 189
F I K + D F ++VSYLEIYNEE+ DLL + + ++ ++E P G+ I L+ V
Sbjct: 123 FKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
Query: 190 NNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLV 249
A D + G+ +R+V +T MN SSRSHAIFTI++E +K D N R KLHLV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS-DKNSSFR-SKLHLV 239
Query: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKST-HVPYRNSKLTRLLQD 308
DLAGSERQ KT A G RLKE IN L LGNVISAL D K VPYR+SKLTRLLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299
Query: 309 SLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIE 368
SLGGNS T+M A + PAD N +ET++TLRYA+RA+ IKNK +N DP+ A L +++++
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQ 359
Query: 369 ELKKKL--EEGEEISGSDISGSEED----DDEEGEVGEDGEKRKKRRGKKKVSPDKMIE- 421
+L+ L G + GS E+ ++ + E+ EK + + +M+E
Sbjct: 360 QLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLER 419
Query: 422 ----------MQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEK 471
M AK++E R+ KLD+++ EL++ + + QQ L ++
Sbjct: 420 IILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDE 479
Query: 472 LSALEKKVIVGGVDLLAKAEEQEKLLEESN-----------------MELEERRKRAEQL 514
A I V+ A+ E + S+ +EL + E L
Sbjct: 480 TVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEAL 539
Query: 515 RRELEEKEQERLDIEEKY----TSLQEEAQGKTKKLKKVWTMLMAAKSE--MADLQQEHQ 568
R++ + + + I+ +Y L+ E K+ +++ L AK + A L + +
Sbjct: 540 ARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRR 599
Query: 569 REIEGLLENIRQLSRELRLQMLII 592
+ ++ L I L ++L Q ++
Sbjct: 600 KRLQELEGQIADLKKKLNEQSKLL 623
Score = 47.8 bits (112), Expect = 4e-05
Identities = 91/475 (19%), Positives = 183/475 (38%), Gaps = 78/475 (16%)
Query: 154 NEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGAT-- 211
+E ++ L+ K+Q+ +E E+ G LS A ++RI+ N + A
Sbjct: 382 SENLQSLMEKNQSL-VEENEKLSRG-----LSEAAGQTAQMLERIILTEQANEKMNAKLE 435
Query: 212 NMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQA-KTGATGQRLKEA 270
+ +H++ + + ++ + N+ + L+ E A A +++
Sbjct: 436 ELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQE 495
Query: 271 TKINLSLSTLGNVISALVDGKSTHVPYRNSKLTR---------LLQDSLGGNSKTMMCAN 321
++ S T S D +T R +++++ L+++L T +
Sbjct: 496 AQVETSPET-----SRSSDAFTTQHALRQAQMSKELVELNKALALKEALA-RKMTQNDSQ 549
Query: 322 IGPADYNYDETISTLRYA---------------NRAKNIKNKARINEDPKDALLRQFQKE 366
+ P Y Y + I L AK N+A+++E + L ++ + +
Sbjct: 550 LQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRL-QELEGQ 608
Query: 367 IEELKKKLEEGEEISGSDISGSEEDDDEEGEVG--------------EDGEKRKKRRGKK 412
I +LKKKL E ++ S E+ ED EK ++ + KK
Sbjct: 609 IADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKK 668
Query: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEE---ERNKARAELEKREKDLLKAQQE----- 464
++ E K E LE + + + A KR KD L+ Q+E
Sbjct: 669 DKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKR 728
Query: 465 ---HQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK 521
+E +A K + ++++ EE ++ L + LE+R+ A+ + + E+K
Sbjct: 729 KETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDL---LEDRKILAQDVAQLKEKK 785
Query: 522 E----------QERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQE 566
E + + E + E TK+++ + T + +++ADLQQ+
Sbjct: 786 ESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK 840
Score = 37.0 bits (84), Expect = 0.062
Identities = 53/236 (22%), Positives = 105/236 (44%), Gaps = 38/236 (16%)
Query: 339 ANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEED------- 391
A +K K E+P L R+ + E++ ++ E E+ I E +
Sbjct: 775 AQDVAQLKEKKESGENPPPKLRRR-TFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQ 833
Query: 392 --DDEEGEVGEDGEKRKKRR------------------GKKKVSPDKMIEMQAKIDEERK 431
D ++ + + E R K+R G+ S ++ ++++ + + +
Sbjct: 834 IADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKT 893
Query: 432 ALETKLDMEEEERNKARAELEKR-EKDLLKAQQEHQ-SLLEKLSALEKKVIVGGVDLLAK 489
+ M EERN AE+E + +L++ +Q+HQ +L LS L++ + +
Sbjct: 894 SCADMQKMLFEERNHF-AEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESV 952
Query: 490 AEEQEKLLEE---SNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGK 542
+E++++LL + ELE+ R+ EQ ++ L E E I++K T LQ ++ K
Sbjct: 953 SEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENE----IIKQKLTLLQVASRQK 1004
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 290 bits (741), Expect = 4e-78
Identities = 212/564 (37%), Positives = 301/564 (53%), Gaps = 40/564 (7%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQ 73
N+KV+ R RPLNE E + K + + +G TV K + FD VF + Q
Sbjct: 8 NIKVMCRFRPLNESEVNRGDKY---IAKFQGEDTVVIAS------KPYAFDRVFQSSTSQ 58
Query: 74 LDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGH 133
VYN A+ I+ VLEGYNGTIFAYGQT +GKT TMEG PE GIIP IF +
Sbjct: 59 EQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNY 118
Query: 134 IAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNAD 193
I + + F ++VSY EIY +++RDLL +T L V E + Y+K + V + D
Sbjct: 119 IYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKT-NLSVHEDKNRVPYVKGCTERFVCSPD 177
Query: 194 DMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAG 253
++ + G NR V TNMNEHSSRSH+IF I ++ + + GKL+LVDLAG
Sbjct: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKL---SGKLYLVDLAG 234
Query: 254 SERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGN 313
SE+ +KTGA G L EA IN SLS LGNVISAL +G ST+VPYR+SK+TR+LQDSLGGN
Sbjct: 235 SEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-STYVPYRDSKMTRILQDSLGGN 293
Query: 314 SKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKK 373
+T + P+ YN ET STL + RAK IKN +N + Q++K+ E+ K+K
Sbjct: 294 CRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVN---VELTAEQWKKKYEKEKEK 350
Query: 374 LEEGEEISGSDISGSEEDDD--EEGE-VGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEER 430
+I + I E + + GE V D + K++ + + DK I + D+
Sbjct: 351 ----NKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTN--DKPA 404
Query: 431 KALETKLDMEEEERNKARAELEKREKDLLKAQQE---HQSLLEKLSALEKKVIVGGVDLL 487
A+ + + ER K E+ K K L +E L+EKL K ++ +LL
Sbjct: 405 TAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKL----KTQMLDQEELL 460
Query: 488 AKAEEQEKLLEESNMELEERRKRAEQ--LRRELEEKEQERLDIEEKYTSLQEEAQGKTKK 545
A ++ NM+ E R +AE + E++E Q ++ Y +E + KTK+
Sbjct: 461 ASTRR-----DQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515
Query: 546 LKKVWTMLMAAKSEMADLQQEHQR 569
+ + L + +A + E Q+
Sbjct: 516 YELLSDELNQKSATLASIDAELQK 539
Score = 42.4 bits (98), Expect = 0.001
Identities = 67/354 (18%), Positives = 139/354 (39%), Gaps = 20/354 (5%)
Query: 268 KEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGG-NSKTMMCANIGPAD 326
K+ T N +T VI D + +KL + L D N ++ + +
Sbjct: 394 KDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQM 453
Query: 327 YNYDETI-STLRYANRAKNIKNKARINEDPKDALLRQFQKEIEEL-----KKKLEEGEEI 380
+ +E + ST R + + N+ + D +++ + +EEL +K E ++
Sbjct: 454 LDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKT 513
Query: 381 SGSDISGSEEDDDEEGEVGEDGEKRKKRR---GKKKVSPDKMIEMQAKIDEERKALETKL 437
++ E + D E +K + +KK + + M + + E A+
Sbjct: 514 KEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNND 573
Query: 438 DMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLL 497
+ E E + K + E ++++++ LE K EE EK L
Sbjct: 574 VKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESN----KKMEENEKEL 629
Query: 498 EESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEE-----AQGKTKKLKKVWTM 552
+ + + + + L L+ EQ++ +EE +L EE AQ K +++K
Sbjct: 630 AACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLN 689
Query: 553 LMAAKSEMAD-LQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIE 605
+ +E+ ++Q+ Q E + I L E+ + +I + ++ + M+E
Sbjct: 690 KVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLE 743
Score = 40.0 bits (92), Expect = 0.007
Identities = 49/266 (18%), Positives = 120/266 (45%), Gaps = 38/266 (14%)
Query: 343 KNIKNKARINEDPKDALLRQF-----QKEIEELKK----KLEEGEEISGS---DISGSEE 390
+N++ K R E+ DAL + Q+++ E++K K++ E+ + I E
Sbjct: 651 QNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRE 710
Query: 391 DDDEE-GEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALET----------KLDM 439
++ + ++ E + K + KM+ Q ++ E + L+ +L +
Sbjct: 711 THQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTV 770
Query: 440 EEEERNKARAELEKREKDLLKAQQEHQSL-----LEKLSALEKKVIVGGVDLLAKAEEQE 494
++ R +AR +L+ E+ + K Q +L + + ++K + D A +++
Sbjct: 771 MQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQ 830
Query: 495 KL-LEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTML 553
K+ E+N+ EQL + ++ ++ D+ + L++ + +++K + + L
Sbjct: 831 KISFLENNL---------EQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESAL 881
Query: 554 MAAKSEMADLQQEHQREIEGLLENIR 579
AK + ++ +Q+E++ + E +R
Sbjct: 882 KEAKENASRDRKRYQQEVDRIKEAVR 907
Score = 38.1 bits (87), Expect = 0.028
Identities = 50/244 (20%), Positives = 116/244 (47%), Gaps = 29/244 (11%)
Query: 361 RQFQKEIEELKKKLEEGE-EISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKM 419
+Q + E KK+EE E E++ + S+ + + + E + ++++ + + S D +
Sbjct: 609 KQLESTQTESNKKMEENEKELAACQLRISQHEAKIKS-LTEYLQNVEQKKRQLEESVDAL 667
Query: 420 IEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKV 479
E ++ + K E ME+E NK + E ++ + Q ++ +++S+L +V
Sbjct: 668 SEELVQLRAQEKVHE----MEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEV 723
Query: 480 IVGG---VDLLAKAEEQEKLLEESNMELEERRKRA--EQLRRELEE-------KEQERLD 527
DL + + Q+ +LE+ + +E + +A ++ R+L E +EQ R D
Sbjct: 724 EAKAKLITDL--QDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQD 781
Query: 528 IEEKYTSLQEEAQGKTKKLKKVWTMLMAAK-SEMADLQQE-------HQREIEGLLENIR 579
++ ++ +E Q L+K++ +A + + A++ + +++I L N+
Sbjct: 782 LKGLEETVAKELQ-TLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLE 840
Query: 580 QLSR 583
QL++
Sbjct: 841 QLTK 844
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 288 bits (737), Expect = 1e-77
Identities = 227/623 (36%), Positives = 336/623 (53%), Gaps = 54/623 (8%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
V V VR RPLN RE+S+ + V +++ D S K+F FD VF
Sbjct: 7 VAVCVRVRPLNSREESL--GETAQVYWKTDNNVIYQVDGS----KSFNFDRVFHGNETTK 60
Query: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGHI 134
+VY A PIIDS ++GYNGTIFAYGQT +GKT+TM G + G+IP + IF I
Sbjct: 61 NVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSE---DHLGVIPRAIHDIFQKI 117
Query: 135 AKAEGDTRFLVRVSYLEIYNEEVRDLL-GKDQTQRLEVKERPDVGVYIKDLSAYVVNNAD 193
K D FL+RVSY+EIYNE + DLL G + + L ++E + VY+ DL+ VV ++
Sbjct: 118 KKFP-DREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSE 176
Query: 194 DMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH--VRMGKLHLVDL 251
+ +T G K+R G T MN+ SSRSH IF + +E EKG N V++ L+LVDL
Sbjct: 177 MALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDL 236
Query: 252 AGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGK-STHVPYRNSKLTRLLQDSL 310
AGSER A+TGA G RLKE IN SL LG VI L DG+ + YR+SKLTR+LQ+SL
Sbjct: 237 AGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSL 296
Query: 311 GGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKD-ALLRQFQKEIEE 369
GGN+KT + I P ++DET++ L++A+ AK +KN +NE D ALL++++KEI +
Sbjct: 297 GGNAKTRIICTITPV--SFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMD 354
Query: 370 LKKKLEEGEEISGSDISGSEEDDD-----EEGEVGEDGEKRKKRRGKKKVSPDKMIEMQA 424
LKK+L EE+S + + E D EE ++ + + K + + + +Q
Sbjct: 355 LKKQL---EEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQ 411
Query: 425 KIDEERKALET-KLDMEEEERNKARAELEKREKDL-LKAQQEHQSLLEKLS---ALEKKV 479
++ +RK T L + +N A+ ++ K + +LL ++ E V
Sbjct: 412 ELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDV 471
Query: 480 IVGGVDLLAKAE--EQEKLLEESNMELEERRKRA---------EQLRRELEEKE---QER 525
+D L++ E KLL + N+E E RA EQLR E EE E +E+
Sbjct: 472 FSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEK 531
Query: 526 LDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADL---QQEHQREIEGLLENIRQLS 582
D++E E + KTKK +++ L+ S + +L + + +++E L + +L
Sbjct: 532 NDLDE-----FEALERKTKKDQEM--QLIHEISNLKNLVKHAEVYNQDLENELSSKVELL 584
Query: 583 RELRLQMLIIDNFIPRDYQEMIE 605
RE Q+ + +I E I+
Sbjct: 585 REKEDQIKKLQEYIDSQKLENIK 607
Score = 55.5 bits (132), Expect = 2e-07
Identities = 80/314 (25%), Positives = 146/314 (46%), Gaps = 64/314 (20%)
Query: 344 NIKNKARINEDPKDAL------LRQFQKEIEELKKKLEE--GEEISGSDISGSEEDDDEE 395
+I + +N D ++ L L+Q Q+ I LK K+ E + + +G +D+ ++
Sbjct: 951 DIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQ 1010
Query: 396 GEVGEDGEKRKKRRGKKKVSPD----KMIEMQAKID---EERKALETKLDMEEEERNKAR 448
VG D ++ + + + ++ D ++IE Q KI +E+ L+ L+ E+ + +
Sbjct: 1011 KMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLK 1070
Query: 449 AEL--------EKREK-----DLLKAQQEHQSLLEKLSALEKKVIVGGV-DLLAKAEE-- 492
+L E +E+ D LK QQE + EK A++K+ + D LA+ EE
Sbjct: 1071 TDLKENIEMTIENQEELRLLGDELKKQQEIVAQ-EKNHAIKKEGELSRTCDRLAEVEEKL 1129
Query: 493 ----------QEKLL--EESNMELEERRKRAEQLRRELEEKE-------QERLDIEEKYT 533
Q++LL +E E++++ E L+ EL+ KE ERL++ +K
Sbjct: 1130 KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLN 1189
Query: 534 SLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIE--GLLENIRQLSRELRLQMLI 591
EE + TK+ +KV L + D + + REIE GL Q EL++ +
Sbjct: 1190 ENYEEVKSITKE-RKVLKELQKSFETERDHLRGYIREIEATGL-----QTKEELKIAHIH 1243
Query: 592 IDNFIPRDYQEMIE 605
+ +++QE I+
Sbjct: 1244 L-----KEHQETID 1252
Score = 55.5 bits (132), Expect = 2e-07
Identities = 60/266 (22%), Positives = 127/266 (47%), Gaps = 28/266 (10%)
Query: 347 NKARINEDPKDALLRQFQKEIEELKKKLEEG-----EEISGSDISGSEEDDDEEGEVGED 401
N+ R+N K+ + QK++E + KL+ E+ +I E ++ E+ +
Sbjct: 1494 NELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF 1553
Query: 402 GEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKA 461
E RK + + KM+E+ ++ E ++ E ++ ++E+E K E + E+D LK
Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRLQESQE--EIQIMIKEKEEMKRVQEALQIERDQLK- 1610
Query: 462 QQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK 521
+ + ++ K+ ++K + + A E QEK+ E+E +++ E + LE
Sbjct: 1611 -ENTKEIVAKMKESQEKE-YQFLKMTAVNETQEKM-----CEIEHLKEQFETQKLNLENI 1663
Query: 522 EQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQ- 580
E E + + + EE + TK+ + ++ +++ + E + L EN+R+
Sbjct: 1664 ETENIRLTQILHENLEEMRSVTKE-----------RDDLRSVEETLKVERDQLKENLRET 1712
Query: 581 LSRELRLQ-MLIIDNFIPRDYQEMIE 605
++R+L Q L I + +++QE I+
Sbjct: 1713 ITRDLEKQEELKIVHMHLKEHQETID 1738
Score = 50.1 bits (118), Expect = 7e-06
Identities = 75/330 (22%), Positives = 131/330 (39%), Gaps = 44/330 (13%)
Query: 360 LRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRK--KRRGKKKVSPD 417
L+ E+E L+K++++ E I SE+D V ++ + + GK K
Sbjct: 749 LKSLPSEVERLRKEIQDKSE--ELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLA 806
Query: 418 KMIEMQAKIDEERKALETKLDMEEEERNK-ARAELEKREKDLLKAQQEHQSLLEKLSALE 476
D+E + +T L M+ E++ K E E+ ++++ +E Q L AL+
Sbjct: 807 TTQSNYKSTDQEFQNFKT-LHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALK 865
Query: 477 KKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQ 536
+L K +E L+E E++ER EQL+ +LE ++ +E + T +
Sbjct: 866 -------TELSYKTQE----LQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLIT 914
Query: 537 EEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGL--------------LENIRQLS 582
E+ Q +++K L K ++ LQ+ Q E + L E +R
Sbjct: 915 EKLQQTLEEVK----TLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNAL 970
Query: 583 RELRLQMLIIDNFIPRDYQEMIENYVHWNEDIG----EWQLKCVAYTGNN----MRKQTP 634
L+ I N + E + +H E+ G E+Q K V QT
Sbjct: 971 ESLKQHQETI-NTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTL 1029
Query: 635 VPDKKEKDPFEVDLSHVYLAYTEESLRQSL 664
D K+ + E L + L+Q L
Sbjct: 1030 TADVKDNEIIEQQRKIFSLIQEKNELQQML 1059
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/268 (21%), Positives = 118/268 (44%), Gaps = 39/268 (14%)
Query: 330 DETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSE 389
+E S + + K IK + D Q ++ I E K++E + ++ E
Sbjct: 1342 EEIKSLTKERDNLKTIKEALEVKHD-------QLKEHIRETLAKIQESQSKQEQSLNMKE 1394
Query: 390 EDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARA 449
+D++ V E + + K D + +I+ E L +L +E
Sbjct: 1395 KDNETTKIVSEMEQFKPK---------DSAL---LRIEIEMLGLSKRLQESHDEMKS--- 1439
Query: 450 ELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRK 509
+ K + DL + Q+ QS ++L K+++ AK E E+ L+ ++ L+E+ +
Sbjct: 1440 -VAKEKDDLQRLQEVLQSESDQLKENIKEIV-------AKHLETEEELKVAHCCLKEQEE 1491
Query: 510 RAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKV-----WTMLMAAKSEMADLQ 564
+LR L EKE E I+++ ++ ++ Q K +++ + + + ++ +L+
Sbjct: 1492 TINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELK 1551
Query: 565 Q--EHQREIEGLLENIRQLSREL--RLQ 588
Q EH++ + L++I EL RLQ
Sbjct: 1552 QFKEHRKAKDSALQSIESKMLELTNRLQ 1579
Score = 48.1 bits (113), Expect = 3e-05
Identities = 53/273 (19%), Positives = 118/273 (43%), Gaps = 33/273 (12%)
Query: 354 DPKDALLRQFQKEIEELKKKLEEGEE-ISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKK 412
D ++ + EI ++K LE + + D+ EE + E E K RG
Sbjct: 1738 DKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIV 1797
Query: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLL---KAQQEHQSLL 469
DK+ MQ ++ L+ K+ EL+ E L+ K E Q +
Sbjct: 1798 SEKTDKLSNMQKDLENSNAKLQEKIQ-----------ELKANEHQLITLKKDVNETQKKV 1846
Query: 470 EKLSALEKKVIVGGVDL-------LAKAEEQEKLLEESNMELEER----------RKRAE 512
++ L+K++ + L L A++ + LEE ++ER + +
Sbjct: 1847 SEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERD 1906
Query: 513 QLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIE 572
QL+ L+E + L+I+++ + + ++ + + K+ + +++D+Q++ + +
Sbjct: 1907 QLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKD 1966
Query: 573 GLLENIRQLSRELRLQMLIIDNFIPRDYQEMIE 605
L + I++L ++ LQ+L + + ++++ E
Sbjct: 1967 ELQKKIQELQKK-ELQLLRVKEDVNMSHKKINE 1998
Score = 47.4 bits (111), Expect = 5e-05
Identities = 74/300 (24%), Positives = 121/300 (40%), Gaps = 47/300 (15%)
Query: 337 RYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEG 396
R A + +K K++ ++ + LL Q+E+ E++KK+ E E + + + E
Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLN-VQEEMSEMQKKINEIENLKNELKNKELTLEHMET 1179
Query: 397 EVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREK 456
E E +K + + K I +ERK L+ E ER+ R + + E
Sbjct: 1180 ERLELAQKLNENYEEVK-----------SITKERKVLKELQKSFETERDHLRGYIREIEA 1228
Query: 457 DLLKAQQE----------HQSLLEKL--SALEKKVIVGGVDLLAKA------------EE 492
L+ ++E HQ +++L S EK + L K+ EE
Sbjct: 1229 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE 1288
Query: 493 QEKLLEESNM-ELEERRKRAEQLRRELEEK--------EQERLDIEEKYTSLQEEAQGKT 543
QE L + E +E E L + K E ERL + EK+ QEE + T
Sbjct: 1289 QELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLT 1348
Query: 544 KKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEM 603
K+ + T+ A + + D +EH RE ++ Q +E L M DN + EM
Sbjct: 1349 KERDNLKTIKEALEVK-HDQLKEHIRETLAKIQE-SQSKQEQSLNMKEKDNETTKIVSEM 1406
Score = 46.6 bits (109), Expect = 8e-05
Identities = 56/262 (21%), Positives = 117/262 (44%), Gaps = 22/262 (8%)
Query: 343 KNIKNKARINEDPKDALLRQFQKEIEELKKKLEEG-EEISGSDISGSEEDDDEEGEVGED 401
+N++ + ++ D LR ++ ++ + +L+E E D+ EE + E
Sbjct: 1676 ENLEEMRSVTKERDD--LRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEH 1733
Query: 402 GEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKA 461
E K RG +++ MQ ++ AL+ + +EE A L+++++ + K
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKL 1793
Query: 462 QQEHQSLLEKLSALEKKVIVGGVDLLAKAEE------QEKLLEESNMELEERRKRAEQLR 515
+ +KLS ++K + L K +E Q L++ E +++ EQL+
Sbjct: 1794 RGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLK 1853
Query: 516 RELEEK-------EQERLDIEEKYTSLQEEAQGKTKK---LKKVWTMLMAAKSEMADLQQ 565
++++++ E E L++ +K EE + K+ L++V L + ++ + Q
Sbjct: 1854 KQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQ 1913
Query: 566 E---HQREIEGLLENIRQLSRE 584
E EI+ L+ R LS+E
Sbjct: 1914 ETKARDLEIQQELKTARMLSKE 1935
Score = 45.1 bits (105), Expect = 2e-04
Identities = 58/270 (21%), Positives = 126/270 (46%), Gaps = 29/270 (10%)
Query: 343 KNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGS-EEDDDEEGEVGED 401
+N+ +++E+ ++ ++ KE + L++ +EE ++ + S +E + E+ ++
Sbjct: 1869 ENLNLAQKLHENLEE--MKSVMKERDNLRR-VEETLKLERDQLKESLQETKARDLEIQQE 1925
Query: 402 GEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKA 461
+ + + K + DK+ E ++ + ++ LD ++E K EL+K+E LL+
Sbjct: 1926 LKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRV 1985
Query: 462 QQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK 521
+++ +K++ + E+ +K E N+ ++ R QL ++L E
Sbjct: 1986 KEDVNMSHKKINEM---------------EQLKKQFEAQNLSMQSVRMDNFQLTKKLHES 2030
Query: 522 -EQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEM-ADLQQEHQREIEG--LLEN 577
E+ R+ +E+ +E + + LK +A EM A +Q HQ + E L +
Sbjct: 2031 LEEIRIVAKER-----DELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDG 2085
Query: 578 IRQLSRELRLQMLIIDNFIPRDYQEMIENY 607
+ L+ LR + I + R Y EM ++Y
Sbjct: 2086 QQHLTESLREKCSRIKELLKR-YSEMDDHY 2114
Score = 33.1 bits (74), Expect = 0.90
Identities = 54/269 (20%), Positives = 114/269 (42%), Gaps = 34/269 (12%)
Query: 331 ETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEE 390
+T+S + + N A + N+ I E ++L + + + ++ E EE+ ++ E+
Sbjct: 477 DTLSEIEW-NPATKLLNQENI-ESELNSLRADYDNLVLDYEQLRTEKEEM---ELKLKEK 531
Query: 391 DDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAE 450
+D +E E E R+ KK + E+ + + A D+E E +K E
Sbjct: 532 NDLDEFEALE-------RKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKV--E 582
Query: 451 LEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKR 510
L + ++D +K QE+ +KL ++ + + + ++ L + + L+ +R+
Sbjct: 583 LLREKEDQIKKLQEYIDS-QKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRES 641
Query: 511 AEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQRE 570
A E L+++EK L + ++ + L A K DL ++E
Sbjct: 642 AFL--------RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDL----EKE 689
Query: 571 IEGLLENIRQLSRELRLQMLIIDNFIPRD 599
++ I +L+ +ID +P+D
Sbjct: 690 LQSAFNEITKLTS-------LIDGKVPKD 711
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 287 bits (735), Expect = 2e-77
Identities = 200/512 (39%), Positives = 275/512 (53%), Gaps = 50/512 (9%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESK- 72
+VKV VR RP N RE S K VS+ T ++ S + PK+FTFD + +
Sbjct: 5 SVKVAVRVRPFNARETSQDAKCVVSMQG--NTTSIINPKQSKDAPKSFTFDYSYWSHTST 62
Query: 73 -------QLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPN 125
Q VY ++ EGYN IFAYGQTG GK++TM G R P +GI+P
Sbjct: 63 EDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-RQEPGQQGIVPQ 121
Query: 126 SFAHIFGHIAKAEG-DTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDL 184
+F +++ + + V VSY+EIY E VRDLL L V+E P +G Y++DL
Sbjct: 122 LCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDL 181
Query: 185 SAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTI--TIECSEK--GIDGNMH 240
S V + D+ +M G+K R+V ATNMNE SSRSHA+FTI T C ++ G+D
Sbjct: 182 SKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSE-- 239
Query: 241 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKSTHV 295
++ K+ LVDLAGSER +GA G RLKE IN SL+TLG VISAL D KS +
Sbjct: 240 -KVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFI 298
Query: 296 PYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDP 355
PYR+S LT LL+++LGGNS+T M A + PAD NY+ET+STLRYA+R K I+ A INEDP
Sbjct: 299 PYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDP 358
Query: 356 KDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVS 415
L+R+ Q+E+ L++ L + +S S + G + EEG V G VS
Sbjct: 359 NARLIRELQEEVARLRELL-MAQGLSASALEGLK---TEEGSV--RGALPAVSSPPAPVS 412
Query: 416 PDKMIEMQAKIDEE-RKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSA 474
P +++ E+++ EE A L++ EK + + + + L K A
Sbjct: 413 PSSPTTHNGELEPSFSPNTESQIGPEE-----AMERLQETEKIIAELNETWEEKLRKTEA 467
Query: 475 LEKKVIVGGVDLLAKAEEQEKLLEESNMELEE 506
L E+E LL E + + E
Sbjct: 468 LRM--------------EREALLAEMGVAVRE 485
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 283 bits (724), Expect = 4e-76
Identities = 190/463 (41%), Positives = 259/463 (55%), Gaps = 28/463 (6%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTIT-VHKTDSSNEPPKTFTFDTVF----G 68
+VKV VR RP N RE S K++ + +M+G T + + E PK+F+FD +
Sbjct: 5 SVKVAVRVRPFNSRETS---KESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTS 61
Query: 69 PE----SKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIP 124
PE + Q VYN + ++ EGYN IFAYGQTG GK++TM G + + GIIP
Sbjct: 62 PEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIP 120
Query: 125 NSFAHIFGHIA-KAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKD 183
+F I + + V VSY+EIY E VRDLL L V+E P +G Y++D
Sbjct: 121 QLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 180
Query: 184 LSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHV-R 242
LS V + D+ +M G+K R+V ATNMNE SSRSHA+FTI + + N+ +
Sbjct: 181 LSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEK 240
Query: 243 MGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKSTHVPY 297
+ K+ LVDLAGSER TGA G RLKE IN SL+TLG VISAL + K+ +PY
Sbjct: 241 VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPY 300
Query: 298 RNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKD 357
R+S LT LL+++LGGNS+T M A + PAD NYDET+STLRYA+RAK IK A INEDP
Sbjct: 301 RDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNA 360
Query: 358 ALLRQFQKEIEELKKKLEE---GEEISGS--DISGSEEDDDEEGEVGEDGEKRKKRRGKK 412
L+R+ ++E+ LK L G+ I S ++ S +VG + R
Sbjct: 361 KLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVTSIQERIMS 420
Query: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKRE 455
++ IE ++ E K + + EE+ K A +RE
Sbjct: 421 TPGGEEAIE---RLKESEKIIAELNETWEEKLRKTEAIRMERE 460
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 283 bits (724), Expect = 4e-76
Identities = 190/463 (41%), Positives = 259/463 (55%), Gaps = 28/463 (6%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTIT-VHKTDSSNEPPKTFTFDTVF----G 68
+VKV VR RP N RE S K++ + +M+G T + + E PK+F+FD +
Sbjct: 5 SVKVAVRVRPFNSRETS---KESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTS 61
Query: 69 PE----SKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIP 124
PE + Q VYN + ++ EGYN IFAYGQTG GK++TM G + + GIIP
Sbjct: 62 PEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIP 120
Query: 125 NSFAHIFGHIA-KAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKD 183
+F I + + V VSY+EIY E VRDLL L V+E P +G Y++D
Sbjct: 121 QLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 180
Query: 184 LSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHV-R 242
LS V + D+ +M G+K R+V ATNMNE SSRSHA+FTI + + N+ +
Sbjct: 181 LSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEK 240
Query: 243 MGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----GKSTHVPY 297
+ K+ LVDLAGSER TGA G RLKE IN SL+TLG VISAL + K+ +PY
Sbjct: 241 VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPY 300
Query: 298 RNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKD 357
R+S LT LL+++LGGNS+T M A + PAD NYDET+STLRYA+RAK IK A INEDP
Sbjct: 301 RDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNA 360
Query: 358 ALLRQFQKEIEELKKKLEE---GEEISGS--DISGSEEDDDEEGEVGEDGEKRKKRRGKK 412
L+R+ ++E+ LK L G+ I S ++ S +VG + R
Sbjct: 361 KLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVTSIQERIMS 420
Query: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKRE 455
++ IE ++ E K + + EE+ K A +RE
Sbjct: 421 TPGGEEAIE---RLKESEKIIAELNETWEEKLRKTEAIRMERE 460
Score = 33.1 bits (74), Expect = 0.90
Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 14/98 (14%)
Query: 446 KARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELE 505
+ARAE EK ++ + ++ LEK+ G+D+ +E EK L+E + +
Sbjct: 593 QARAEREKTPSAETPSEPVDWTFAQR-ELLEKQ----GIDM---KQEMEKRLQEMEILYK 644
Query: 506 ERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKT 543
+ ++ A+ L EQ+RLD E K +LQ++ + ++
Sbjct: 645 KEKEEADLLL------EQQRLDYESKLQALQKQVETRS 676
Score = 30.8 bits (68), Expect = 4.5
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 449 AELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERR 508
A+ E EK + +QE + L+++ L KK DLL EQ++L ES ++ +++
Sbjct: 616 AQRELLEKQGIDMKQEMEKRLQEMEILYKKE-KEEADLLL---EQQRLDYESKLQALQKQ 671
Query: 509 KRAEQLRRELEEKEQERLDI 528
L E E+E+E ++
Sbjct: 672 VETRSLAAETTEEEEEEEEV 691
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 279 bits (713), Expect = 7e-75
Identities = 170/383 (44%), Positives = 225/383 (58%), Gaps = 26/383 (6%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRG-TITVHKTDSSNEPPKTFTFDTVF----G 68
+VKV VR RP N RE S + + + +M G T T+ E PK+F+FD +
Sbjct: 5 SVKVAVRVRPFNSREMS---RDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTS 61
Query: 69 PE----SKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIP 124
PE + Q VY ++ EGYN IFAYGQTG GK++TM G + + +GIIP
Sbjct: 62 PEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQE-KDQQGIIP 120
Query: 125 NSFAHIFGHIAKAEGDTR-FLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKD 183
+F I D + V VSY+EIY E VRDLL L V+E P +G Y++D
Sbjct: 121 QLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 180
Query: 184 LSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHV-R 242
LS V + +D+ +M G+K R+V ATNMNE SSRSHA+F I + N+ +
Sbjct: 181 LSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEK 240
Query: 243 MGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-----------GK 291
+ K+ LVDLAGSER TGA G RLKE IN SL+TLG VISAL + K
Sbjct: 241 VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKK 300
Query: 292 STHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARI 351
+ +PYR+S LT LL+++LGGNS+T M A + PAD NYDET+STLRYA+RAK I+ A I
Sbjct: 301 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVI 360
Query: 352 NEDPKDALLRQFQKEIEELKKKL 374
NEDP + L+R+ + E+ L+ L
Sbjct: 361 NEDPNNKLIRELKDEVTRLRDLL 383
Score = 33.5 bits (75), Expect = 0.69
Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 9/59 (15%)
Query: 493 QEKLLEESNM----ELEERRKRAE-QLRRELEEK----EQERLDIEEKYTSLQEEAQGK 542
Q +LLE+ + E+E+R + E Q RRE EE EQ+RLD E K +LQ++ +
Sbjct: 623 QRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSR 681
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 270 bits (691), Expect = 3e-72
Identities = 157/374 (41%), Positives = 231/374 (61%), Gaps = 21/374 (5%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
VKV VR RPL +E ++ V V + + + + FTFD VFG S Q
Sbjct: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-------RVFTFDFVFGKNSTQD 58
Query: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEG---VRAIPELRGIIPNSFAHIF 131
+VYN +P++ S++EGYN T+FAYGQTG+GKT+T+ G + +GIIP + IF
Sbjct: 59 EVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIF 118
Query: 132 GHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQR-LEVKERPDVGVYIKDLSAYVVN 190
I++ F V+VSY+E+Y E++RDLL + + + L ++E I V
Sbjct: 119 QSISE-HPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVE 177
Query: 191 NADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITI-------ECSEKGIDGNMHVRM 243
+A ++ ++ +G+ R G T MNEHSSRSHAIFTI+I E +E G + +
Sbjct: 178 SAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIV 237
Query: 244 GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDG--KSTHVPYRNSK 301
K H VDLAGSER KTG TG+R KE+ +IN L LGNVISAL D KS+H+PYR++K
Sbjct: 238 SKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAK 297
Query: 302 LTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLR 361
+TRLL+DSLGG++KT+M + P+ N+DE++++L+YANRA+NI+NK +N P+ +
Sbjct: 298 ITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRID 357
Query: 362 QFQKEIEELKKKLE 375
+ + EI+ L++ L+
Sbjct: 358 EMEFEIKLLREALQ 371
Score = 57.4 bits (137), Expect = 4e-08
Identities = 63/286 (22%), Positives = 125/286 (43%), Gaps = 40/286 (13%)
Query: 336 LRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEE 395
++ N AK++ + + + Q + E+ E +K+L+E E SD++ + E
Sbjct: 744 IKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEF 803
Query: 396 GEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLD-------------MEEE 442
+ + + R + KK+ K+ + + ++ LE +D EE
Sbjct: 804 RKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREEN 863
Query: 443 ERNKARAELEKREKDLLKAQQ----EHQSLLEKLSALE------KKVIVGGVDLLAKAEE 492
E+ K + KR++ +K Q + + L K L+ +K G +D L K +E
Sbjct: 864 EKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDE 923
Query: 493 QEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLK----- 547
Q+K L+E ++ +R+ E+L +L+++E + +K LQE++ + KKL+
Sbjct: 924 QKKWLDEEVEKVLNQRQELEELEADLKKRE---AIVSKKEALLQEKSHLENKKLRSSQAL 980
Query: 548 -----KVWTMLMAAKSEMAD----LQQEHQREIEGLLENIRQLSRE 584
K+ T L + E+++ LQ E + E + L +E
Sbjct: 981 NTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKE 1026
Score = 53.5 bits (127), Expect = 6e-07
Identities = 77/375 (20%), Positives = 162/375 (43%), Gaps = 32/375 (8%)
Query: 267 LKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPAD 326
LKEA K+N + LVD S + N +T +++ G + P
Sbjct: 524 LKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPER-RPYT 582
Query: 327 YNYDETISTLRYANRAKNIKNKARINEDPK----DALLRQFQKEIEELKKKLEEGEEISG 382
+D + Y ++ + +++ P D + F+ + L +EE +++
Sbjct: 583 VPFDTHLGHYIYIPSRQDSR---KVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLH 639
Query: 383 SDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKA----LETKLD 438
S + +D++ EG+ R + +K S ++E+ DE +K+ + K+D
Sbjct: 640 CQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKID 699
Query: 439 MEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALE---KKVIVGGVDLLAKAEEQEK 495
+E + +L+ E+ L +A+Q+ + L + E K++I G D AK+ ++
Sbjct: 700 CLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGND--AKSVSKQY 757
Query: 496 LLEESNMELEERRKRAE--QLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTML 553
L+ + +E + + + E + +++L+E E + L LQ+E + K K +L
Sbjct: 758 SLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVL 817
Query: 554 MAAKSEMADL------QQEHQREIEGLLENIR----QLSRELRLQ---MLIIDNFIPRDY 600
+ + L ++ E+E +++++ QL R+LR + +D I RD
Sbjct: 818 QKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQ 877
Query: 601 QEMIENYVHWNEDIG 615
Q++ E + ++ G
Sbjct: 878 QKIKEIQLKTGQEEG 892
Score = 49.3 bits (116), Expect = 1e-05
Identities = 94/410 (22%), Positives = 169/410 (41%), Gaps = 101/410 (24%)
Query: 245 KLHLVDLAGSER---QAKTGATGQRLKEAT-KINLSLSTLGNVISALVDGKSTHVPYRNS 300
+L+L L SER +AK Q+++E T I + + +I D KS Y +
Sbjct: 706 ELNLQKLKNSERILTEAK-----QKMRELTINIKMKEDLIKELIKTGNDAKSVSKQY-SL 759
Query: 301 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 360
K+T+L D A+ E I T + + + ++NK + K L
Sbjct: 760 KVTKLEHD----------------AEQAKVELIETQK---QLQELENKDLSDVAMKVKLQ 800
Query: 361 RQFQKE-------IEELKKKLEEGEEISGSDISGSEEDDDEEGEVG-------------- 399
++F+K+ ++ L+KK ++ ++++ I + ++ E V
Sbjct: 801 KEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLR 860
Query: 400 EDGEKRKKRRGKKKVSPDKMIEMQAK----------------------------IDEERK 431
E+ EKRK+ K K+ E+Q K ID +K
Sbjct: 861 EENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQK 920
Query: 432 ALETK--LDMEEEERNKARAELEKREKDLLKAQ---QEHQSLLEKLSALEKKVI------ 480
E K LD E E+ R ELE+ E DL K + + ++LL++ S LE K +
Sbjct: 921 LDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQAL 980
Query: 481 -VGGVDLLAKAEEQEKLLEESNMEL-----EERRKRAEQ---LRRELEEKEQERLDIEEK 531
+ + + E+ L E N++L EE+ K +EQ L++E ++ ++ R +++EK
Sbjct: 981 NTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEK 1040
Query: 532 YTS---LQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENI 578
+ L E + +L++ L AA + Q Q+ + N+
Sbjct: 1041 LKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNL 1090
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 266 bits (679), Expect = 6e-71
Identities = 199/615 (32%), Positives = 311/615 (50%), Gaps = 65/615 (10%)
Query: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQ 73
+V+V VR RP +EK SV + + K K FTFD VF +S+Q
Sbjct: 9 SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKD-------KAFTFDYVFDIDSQQ 61
Query: 74 LDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTME---GVRAIPELRGIIPNSFAHI 130
+Y +I+ EGYN T+FAYGQTG GKT+TM V + E GII + H+
Sbjct: 62 EQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHL 121
Query: 131 FG------HIAKAEG--DTRFLVRVSYLEIYNEEV-------RDLLGKDQTQRLEVKERP 175
F HIA G F V +LE+YNEEV RD+ K + + + E
Sbjct: 122 FKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDS 181
Query: 176 DVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTI----TIEC- 230
G+Y ++ VN +M + + LG +R+ +T MN SSRSHAIFTI T C
Sbjct: 182 TGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCP 241
Query: 231 -------------SEKGIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSL 277
SE K H VDLAGSER +TGATG+R KE IN L
Sbjct: 242 QIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 301
Query: 278 STLGNVISALVDG--KSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETIST 335
LGNVISAL D ++THVPYR+SKLTRLLQDSLGGNS+T+M A + P+D ++ ET++T
Sbjct: 302 LALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 361
Query: 336 LRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEE---GEEISGSDISGSEEDD 392
L+YANRA+NIKNK +N+D + + EI L+ +L E G+ I D G E +
Sbjct: 362 LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRI--IDEEGVESIN 419
Query: 393 DEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKI-----DEERKALETKLDMEEEERNKA 447
D E + R + K + + ++++I D+ L + EE N
Sbjct: 420 DMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMI 479
Query: 448 RA---ELEKREKDLLKAQQEHQSLLEKLS-ALEKKVIVGGVD-----LLAKAEEQEKLLE 498
+ E+E LL+++ +++L + L+ A + G +L+ +E ++++
Sbjct: 480 HSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIID 539
Query: 499 ESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKS 558
+ +LE+ +++ ++ ++ + KE + D +++ + ++ + +L+ + ++
Sbjct: 540 LAKKDLEKLKRKEKRKKKSVAGKE-DNTDTDQEKKEEKGVSERENNELEVEESQEVSDHE 598
Query: 559 EMADLQQEHQREIEG 573
+ + ++E + +I+G
Sbjct: 599 DEEEEEEEEEDDIDG 613
Score = 55.1 bits (131), Expect = 2e-07
Identities = 86/404 (21%), Positives = 160/404 (39%), Gaps = 68/404 (16%)
Query: 331 ETISTLR------YANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEI---- 380
ET+ LR +++A ++ +A + ++ + KEIE+L+ KL E E +
Sbjct: 444 ETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENL 503
Query: 381 --------------SGSD------ISGSEEDDDEEGEVGEDGEK--RKKRRGKKKVS--P 416
SGS +S +E + +D EK RK++R KK V+
Sbjct: 504 RKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKE 563
Query: 417 DKMIEMQAKIDE------ERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLE 470
D Q K +E E LE + E + E E+ E D+ + +S E
Sbjct: 564 DNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE 623
Query: 471 KLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK--------- 521
+ + + + ++KL++E LE +KR + L+++ EEK
Sbjct: 624 SDEKANYQADLANIT--CEIAIKQKLIDE----LENSQKRLQTLKKQYEEKLMMLQHKIR 677
Query: 522 --EQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIR 579
+ ER + + S++ ++ K KK++ + + A ++ Q Q+E LL+N
Sbjct: 678 DTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQS 737
Query: 580 QLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKK 639
Q ++L+ + +D EM + V + + E Q K R+ + +
Sbjct: 738 QYEKQLKK--------LQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQ 789
Query: 640 EKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGR 683
K ++ L E LR+ K E + + RP + +
Sbjct: 790 RKRDHQLRLLEAQKRNQEVVLRR---KTEEVTALRRQVRPMSDK 830
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 263 bits (673), Expect = 3e-70
Identities = 193/587 (32%), Positives = 294/587 (50%), Gaps = 71/587 (12%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
VKV VR RP +EK SV + + K K FT+D VF ++ Q
Sbjct: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD-------KAFTYDFVFDLDTWQE 61
Query: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTME---GVRAIPELRGIIPNSFAHIF 131
+Y+ +I+ EGYN T+ AYGQTG GKT+TM + E +GIIP + AH+F
Sbjct: 62 QIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLF 121
Query: 132 GHIAKAE--------GDTRFLVRVSYLEIYNEEVRDLLG-------KDQTQRLEVKERPD 176
G IA+ + F V +LE+YNEE+ DL + + +++ E +
Sbjct: 122 GGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDAN 181
Query: 177 VGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITI----ECSE 232
G+Y +++ ++++ +++ + + G +R+ +T MN SSRSHAIFTI + C++
Sbjct: 182 GGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQ 241
Query: 233 KGI---------DGN-----MHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLS 278
+ DG K H VDLAGSER +TGATG+R KE IN L
Sbjct: 242 PDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLL 301
Query: 279 TLGNVISALVDG--KSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTL 336
LGNVISAL D K HVPYR+SKLTRLLQDSLGGNS+T+M A + P+D ++ ET++TL
Sbjct: 302 ALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTL 361
Query: 337 RYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEE---GEEISGSDISGSEEDDD 393
+YANRA+NIKNK +N+D + + EI L+ +L E G+ + G D + D
Sbjct: 362 KYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLF 421
Query: 394 EEGEV--GEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEE-----RNK 446
E + E+G R + + ++ + + +E L K E +N
Sbjct: 422 RENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNY 481
Query: 447 ARAELEKREKDLLKAQQEHQSLLEKLSALEKK----------VIVGGVDLLAKAEEQEKL 496
R E+E+ LL+++ ++SL LS + G + E+ ++
Sbjct: 482 IR-EIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV 540
Query: 497 LEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKT 543
+ + +LE +K+ + RR+ EKE + K LQ+E +T
Sbjct: 541 IRRAKQDLERLKKKEVRQRRKSPEKEAFK-----KRAKLQQENSEET 582
Score = 60.5 bits (145), Expect = 5e-09
Identities = 67/285 (23%), Positives = 127/285 (44%), Gaps = 50/285 (17%)
Query: 348 KARINEDPKDALLRQFQKEIEELKKKLEEGEEIS-------------------------- 381
KA + AL++ + +EIEEL+ KL E E ++
Sbjct: 466 KAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPA 525
Query: 382 --GSDISGSEEDDDEEGEVGEDGEKRKKRRGK-KKVSPDK-MIEMQAKIDEERKALETKL 437
GS S E+ + +D E+ KK+ + ++ SP+K + +AK+ +E +
Sbjct: 526 FGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDEN 585
Query: 438 DMEE--EERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI---VGGVDLLAKAEE 492
+ EE EER+++ E E+ +D + +SL++ S E+K + DL + E
Sbjct: 586 EAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEI 645
Query: 493 QEKLLEESNMELEERRKRAEQLRRELEEK-----------EQERLDIEEKYTSLQEEAQG 541
++KL++ ELE ++R + L+ + EEK + ER + + ++++ +
Sbjct: 646 KQKLID----ELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEE 701
Query: 542 KTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELR 586
K K+K + + + Q Q+E LL+N + REL+
Sbjct: 702 KANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELK 746
Score = 33.5 bits (75), Expect = 0.69
Identities = 38/196 (19%), Positives = 83/196 (42%), Gaps = 30/196 (15%)
Query: 328 NYDETISTLRYANRAKNI--KNKARINEDPKDALLRQF-------QKEIEELKKKLEEGE 378
N + TL++ K I +NK R + +D +L+ +++ ++K E+
Sbjct: 655 NSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRL 714
Query: 379 EISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLD 438
D+ + E + ++ + R +R KK +QA++ E +KA +
Sbjct: 715 REMNRDLQKLQAAQKEHARLLKN-QSRYERELKK---------LQAEVAEMKKAKVALMK 764
Query: 439 MEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLE 498
EE+ + R KR +++ + ++E + ++ ALE ++ +QE +L
Sbjct: 765 QMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALE-----------SQKRQQEMVLR 813
Query: 499 ESNMELEERRKRAEQL 514
E+ R+ A+ +
Sbjct: 814 RKTQEVSALRRLAKPM 829
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 261 bits (667), Expect = 2e-69
Identities = 200/612 (32%), Positives = 315/612 (51%), Gaps = 58/612 (9%)
Query: 12 CDNVKVVVRCRPLNEREKSMCYKQAVSV--------DEMRGTITVH---KTDSSNEPPKT 60
C ++KVVVR RP N +EK+ + + V V D + ++ KT + N K
Sbjct: 9 CHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQ 68
Query: 61 -----FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRA 115
F FD VF S Q +V+ T +PI+ S L GYN T+ AYG TG GKT TM G
Sbjct: 69 NKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSAD 128
Query: 116 IPELRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERP 175
P G++ + H++ + + + + VSYLE+YNE++RDLL L V+E
Sbjct: 129 EP---GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDT 183
Query: 176 DVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGI 235
GV + L+ + +++++ ++ G+KNR+ T+MN SSRSHA+F I + +K
Sbjct: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
Query: 236 DGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDG--KST 293
N +VR+ K+ L+DLAGSER + +GA G R E T IN SL LGNVI+AL D K+
Sbjct: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
Query: 294 HVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINE 353
H+PYRNSKLTRLL+DSLGGN +T+M A + P+ YD+T +TL+YANRAK+IK+ + N
Sbjct: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
Query: 354 DPKDALLRQFQK-------EIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRK 406
+ + Q+ K EI LK+KL+ EE + + E+D + + EK
Sbjct: 364 LNVNNHITQYVKICNEQKAEILLLKEKLKAYEE----QKAFTNENDQAKLMISNPQEKEI 419
Query: 407 KR---------RGKKKVSPDKM-IEMQAKIDEERKALETKLDMEEE---ERNKARAELEK 453
+R + ++++ + + +EM K +E + + + + E +K K
Sbjct: 420 ERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGK 479
Query: 454 REKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQ 513
R+ L + +S LEK E K + L + E++ LL ++ +E +K
Sbjct: 480 RDHRLAML-KTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHC 538
Query: 514 LRRELEEKE-----QERLDI----EEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQ 564
L+ K+ + +D+ E+++ + L+K + L A A +
Sbjct: 539 HHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFE 598
Query: 565 QEHQREIEGLLE 576
+ +EIE L+E
Sbjct: 599 SDF-KEIEHLVE 609
>gi|157502184 kinesin family member 6 [Homo sapiens]
Length = 814
Score = 260 bits (665), Expect = 3e-69
Identities = 194/581 (33%), Positives = 291/581 (50%), Gaps = 75/581 (12%)
Query: 61 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
F F +F ++ Q V+ A+P+ SVL GYNGTIFAYGQTG+GKTFT+ G R
Sbjct: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
Query: 121 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGK-------DQTQRLEVKE 173
GIIP + ++IF + K + + +SYLEIYNE DLL + ++ + E
Sbjct: 118 GIIPRTLSYIFEQLQK-DSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
Query: 174 RPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEK 233
PD +++K+L+ + ++ ++ LG NR + T MN+ S+RSH IFTI + E
Sbjct: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEP 236
Query: 234 GIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKST 293
G + VR KLHLVDLAGSER AKTG G L EA INLSL L VI AL + +
Sbjct: 237 G---SATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRS 293
Query: 294 HVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINE 353
H+PYRNS +T +L+DSLGGN T M A + N DE+IST R+A R IKN+A +NE
Sbjct: 294 HIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNE 353
Query: 354 DPKDAL-LRQFQKEIEELKKKL------EEGEEISGSDISGSE---------EDDDEEGE 397
+ L +++ QKEI+ELK +L + E ++ +++ E +D D E
Sbjct: 354 EINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLE 413
Query: 398 VGEDGEK-RKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREK 456
VG D K KK+ DK I + E K + + ++EEE K R
Sbjct: 414 VGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLR-------- 465
Query: 457 DLLKAQQEHQSLLEKLSALEKK-----VIVGGVDLLAKAEEQEKLLEESNMELEERR--- 508
D+LK + ++L + EKK + + G+D + Q N E +R
Sbjct: 466 DILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLS 525
Query: 509 -------------KRAEQLRRELEEKEQERLDIEEKYTSLQEE-------------AQGK 542
KR+ L +++ +E+ L +E + + + + +
Sbjct: 526 SAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQR 585
Query: 543 TKKLKKVWTMLMAAKSEMADLQQE-HQREIE----GLLENI 578
+ K + + A+S++ L++E QR I+ G+ EN+
Sbjct: 586 FSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENM 626
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 254 bits (648), Expect = 2e-67
Identities = 181/561 (32%), Positives = 286/561 (50%), Gaps = 58/561 (10%)
Query: 15 VKVVVRCRPLNEREKSMCYKQAVSV----------DEMRGTITVHKTDSSNEPPK----- 59
++VVVR RP RE + V V +E G K +++ PK
Sbjct: 8 LQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKD 67
Query: 60 -TFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPE 118
TF FD VFG + Q DV+ T ++DS L+GYN ++FAYG TG GKT TM G P
Sbjct: 68 LTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDP- 126
Query: 119 LRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVG 178
GI+ + ++ + + + F V +SY E+YNE++ DLL + L ++E PD G
Sbjct: 127 --GIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLL--EPKGPLAIREDPDKG 182
Query: 179 VYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGN 238
V ++ LS + +A+ + I+T G++NR+ T+ N SSRSHAIF I ++ ++
Sbjct: 183 VVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLT 242
Query: 239 MHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD--GKSTHVP 296
V++ K+ L+DLAGSER + T A G+RL+E IN SL L NV++AL D G+ THVP
Sbjct: 243 QAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKTHVP 302
Query: 297 YRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPK 356
YR+SKLTRLL+DSLGGN +T+M A I P+ Y++T +TL+YA+RAK I+ + N
Sbjct: 303 YRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLSLKSNVTSL 362
Query: 357 D-------ALLRQFQKEIEELKKKLE--EG------EEISGSDISGSEEDDDEEGEVGED 401
D + +Q Q E+ L+KKL+ EG +++ GS SG + +
Sbjct: 363 DCHISQYATICQQLQAEVAALRKKLQVYEGGGQPPPQDLPGSPKSGPPPEHLPSSPLPPH 422
Query: 402 GEKR---KKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDL 458
+ + + ++ + M+A++ ER D E+ ++ E+ +
Sbjct: 423 PPSQPCTPELPAGPRALQEESLGMEAQV--ERAMEGNSSDQEQSPEDEDEGPAEEVPTQM 480
Query: 459 LKAQQEHQSLLEKLSALEKKVIVG---------------GVDLLAKAEEQEKLLEESNME 503
+ H L+ K +VG + +L A+ Q LL+ +N+
Sbjct: 481 PEQNPTHALPESPRLTLQPKPVVGHFSARELDGDRSKQLALKVLCVAQRQYSLLQAANLL 540
Query: 504 LEERRKRAEQLRRELEEKEQE 524
+ E L++ ++E++ E
Sbjct: 541 TPDMITEFETLQQLVQEEKIE 561
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 252 bits (643), Expect = 9e-67
Identities = 193/639 (30%), Positives = 315/639 (49%), Gaps = 52/639 (8%)
Query: 17 VVVRCRPLNERE---------KSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVF 67
V +R RP++ E + + V +D M + + S E K++ FD F
Sbjct: 14 VALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSRE--KSYLFDVAF 71
Query: 68 GPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSF 127
+ Q VY T + +I+ V+ GYN T+FAYG TG GKT+TM G P GI +
Sbjct: 72 DFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEP---GIYVQTL 128
Query: 128 AHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAY 187
+F I + D + V +SYLEIYNE +RDLL LE++E + + ++
Sbjct: 129 NDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGY-LELREDSKGVIQVAGITEV 187
Query: 188 VVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLH 247
NA ++ +++ G++ R+ T N+ SSRSHA+ +T+ + + VR G+L
Sbjct: 188 STINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQGRLF 247
Query: 248 LVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD-GKSTHVPYRNSKLTRLL 306
++DLAGSER ++T GQR+KE IN SL LGN I+AL D G + ++ YR+SKLTRLL
Sbjct: 248 MIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRLL 307
Query: 307 QDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN-------EDPKDAL 359
+DSLGGNS+T+M A+I PA ++E+ +TL YA RAKNIK + + N ++
Sbjct: 308 KDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQYTSI 367
Query: 360 LRQFQKEIEELKKKLEE--------GEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGK 411
+ + EI+ LK+K++E G + G DI + + GE + R
Sbjct: 368 IADLRGEIQRLKRKIDEQTGRGQARGRQDRG-DIRHIQAEVQLHSGQGEKAGMGQLREQL 426
Query: 412 KKVSPDKMIEMQAKIDEERKALETKLD-----------MEEEERNKARAELEKREKDLLK 460
++M + ++ E +A+E ++D E+ R + E+R++ K
Sbjct: 427 ASAFQEQMDVRRRLLELENRAMEVQIDTSRHLLTIAGWKHEKSRRALKWREEQRKECYAK 486
Query: 461 AQQEHQSLL--EKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRREL 518
E S ++ LE + + +A +++K L + + LE+R + R L
Sbjct: 487 DDSEKDSDTGDDQPDILEPPEVAAARESIAALVDEQKQLRKQKLALEQRCRELRARGRRL 546
Query: 519 EEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENI 578
EE R+ EE+ L + +++ M + + + D H+ E LE
Sbjct: 547 EETLPRRIGSEEQREVLSLLCRVHELEVENT---EMQSHALLRDGALRHRHEAVRRLEQH 603
Query: 579 RQLSRE-LRLQMLIIDNF---IPRDYQEMIENYVHWNED 613
R L E ++ Q IID++ +P+ +E+ E Y+ E+
Sbjct: 604 RSLCDEIIQGQRQIIDDYNLAVPQRLEELYEVYLRELEE 642
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,483,679
Number of Sequences: 37866
Number of extensions: 1240788
Number of successful extensions: 28407
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 768
Number of HSP's successfully gapped in prelim test: 1369
Number of HSP's that attempted gapping in prelim test: 8139
Number of HSP's gapped (non-prelim): 8929
length of query: 699
length of database: 18,247,518
effective HSP length: 109
effective length of query: 590
effective length of database: 14,120,124
effective search space: 8330873160
effective search space used: 8330873160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.