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Search of human proteins with 46275839
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46275839 hypothetical protein LOC135154 [Homo sapiens]
(108 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46275839 hypothetical protein LOC135154 [Homo sapiens] 231 7e-62
gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H... 33 0.065
gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H... 33 0.065
gi|206725422 G protein-coupled receptor kinase interacting ArfGA... 31 0.19
gi|206725420 G protein-coupled receptor kinase interacting ArfGA... 31 0.19
gi|21237786 G protein-coupled receptor kinase interacting ArfGAP... 31 0.19
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 30 0.32
gi|21687224 solute carrier family 30 (zinc transporter), member ... 30 0.32
gi|56549694 enabled homolog isoform a [Homo sapiens] 30 0.55
gi|39930375 enabled homolog isoform b [Homo sapiens] 30 0.55
gi|169167750 PREDICTED: similar to hCG1642908 [Homo sapiens] 30 0.55
gi|169168508 PREDICTED: similar to hCG1642908 [Homo sapiens] 30 0.55
gi|239742494 PREDICTED: similar to hCG1642908 [Homo sapiens] 30 0.55
gi|34878787 ring finger protein 25 [Homo sapiens] 30 0.55
gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens] 30 0.55
gi|28559039 mediator complex subunit 1 [Homo sapiens] 29 0.71
gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens] 29 0.93
gi|4557509 cylicin 2 [Homo sapiens] 28 1.6
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] 28 1.6
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 28 1.6
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 28 1.6
gi|117320550 hypothetical protein LOC400566 [Homo sapiens] 28 1.6
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 27 2.7
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 27 2.7
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 27 2.7
gi|122937514 unc-13 homolog C [Homo sapiens] 27 2.7
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 27 3.5
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 27 3.5
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 27 3.5
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 27 3.5
>gi|46275839 hypothetical protein LOC135154 [Homo sapiens]
Length = 108
Score = 231 bits (590), Expect = 7e-62
Identities = 108/108 (100%), Positives = 108/108 (100%)
Query: 1 MTPSRLPWLLSWVSATAWRAARSPLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDA 60
MTPSRLPWLLSWVSATAWRAARSPLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDA
Sbjct: 1 MTPSRLPWLLSWVSATAWRAARSPLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDA 60
Query: 61 PEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTRYGDWERKGRCIDF 108
PEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTRYGDWERKGRCIDF
Sbjct: 61 PEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTRYGDWERKGRCIDF 108
>gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform b [Homo sapiens]
Length = 2347
Score = 32.7 bits (73), Expect = 0.065
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 24 PLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTK 83
PL S R T+ S L +Q EG+ D+P D+ EP EK P V PVT+
Sbjct: 1988 PLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTP--VRPVTQ 2045
Query: 84 E---KGGPRGPEP 93
+ PR P P
Sbjct: 2046 GGSLQSPPRSPRP 2058
>gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform a [Homo sapiens]
Length = 2353
Score = 32.7 bits (73), Expect = 0.065
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 24 PLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTK 83
PL S R T+ S L +Q EG+ D+P D+ EP EK P V PVT+
Sbjct: 1994 PLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTP--VRPVTQ 2051
Query: 84 E---KGGPRGPEP 93
+ PR P P
Sbjct: 2052 GGSLQSPPRSPRP 2064
>gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 5 [Homo sapiens]
Length = 729
Score = 31.2 bits (69), Expect = 0.19
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 29 SLRKTSSSQGGKSELVKQ--SLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKG 86
SL++ S++G + + + S +KP LP G PE+S + +P FP + + K+
Sbjct: 500 SLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRMRLQP---FPAHASRLEKQNS 556
Query: 87 GPRGPEPTRYGDWERKG 103
P D E G
Sbjct: 557 TPESDYDNTPNDMEPDG 573
>gi|206725420 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 6 [Homo sapiens]
Length = 681
Score = 31.2 bits (69), Expect = 0.19
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 29 SLRKTSSSQGGKSELVKQ--SLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKG 86
SL++ S++G + + + S +KP LP G PE+S + +P FP + + K+
Sbjct: 452 SLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRMRLQP---FPAHASRLEKQNS 508
Query: 87 GPRGPEPTRYGDWERKG 103
P D E G
Sbjct: 509 TPESDYDNTPNDMEPDG 525
>gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 3 [Homo sapiens]
Length = 679
Score = 31.2 bits (69), Expect = 0.19
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 29 SLRKTSSSQGGKSELVKQ--SLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKG 86
SL++ S++G + + + S +KP LP G PE+S + +P FP + + K+
Sbjct: 450 SLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRMRLQP---FPAHASRLEKQNS 506
Query: 87 GPRGPEPTRYGDWERKG 103
P D E G
Sbjct: 507 TPESDYDNTPNDMEPDG 523
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 30.4 bits (67), Expect = 0.32
Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 9/72 (12%)
Query: 31 RKTSSSQGGKSELVKQSLKKPK-----LPEGRFD----APEDSHLEKEPLEKFPDDVNPV 81
RK S S+ EL ++ K K L EGR AP KEP +
Sbjct: 206 RKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLES 265
Query: 82 TKEKGGPRGPEP 93
T KGGP P P
Sbjct: 266 TSPKGGPPPPPP 277
>gi|21687224 solute carrier family 30 (zinc transporter), member 6
[Homo sapiens]
Length = 461
Score = 30.4 bits (67), Expect = 0.32
Identities = 14/31 (45%), Positives = 16/31 (51%)
Query: 63 DSHLEKEPLEKFPDDVNPVTKEKGGPRGPEP 93
D H+ PL K DD+NPVT P P P
Sbjct: 355 DHHVIPMPLLKGTDDLNPVTSTPAKPSSPPP 385
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 29.6 bits (65), Expect = 0.55
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 60 APEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTRYGDWER 101
A + S +E E E +D PVT + PEPTR WER
Sbjct: 459 AEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTR-KPWER 499
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 29.6 bits (65), Expect = 0.55
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 60 APEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTRYGDWER 101
A + S +E E E +D PVT + PEPTR WER
Sbjct: 459 AEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTR-KPWER 499
>gi|169167750 PREDICTED: similar to hCG1642908 [Homo sapiens]
Length = 193
Score = 29.6 bits (65), Expect = 0.55
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 15 ATAWRAARSPLLCHSLRKTSSSQGG 39
ATAW+A R PL + RK +S GG
Sbjct: 56 ATAWQAPRKPLATKAARKRASPTGG 80
>gi|169168508 PREDICTED: similar to hCG1642908 [Homo sapiens]
Length = 193
Score = 29.6 bits (65), Expect = 0.55
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 15 ATAWRAARSPLLCHSLRKTSSSQGG 39
ATAW+A R PL + RK +S GG
Sbjct: 56 ATAWQAPRKPLATKAARKRASPTGG 80
>gi|239742494 PREDICTED: similar to hCG1642908 [Homo sapiens]
Length = 147
Score = 29.6 bits (65), Expect = 0.55
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 15 ATAWRAARSPLLCHSLRKTSSSQGG 39
ATAW+A R PL + RK +S GG
Sbjct: 11 ATAWQAPRKPLATKAARKRASPTGG 35
>gi|34878787 ring finger protein 25 [Homo sapiens]
Length = 459
Score = 29.6 bits (65), Expect = 0.55
Identities = 31/112 (27%), Positives = 41/112 (36%), Gaps = 33/112 (29%)
Query: 26 LCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLE------------------ 67
+C + T S+Q E K L PK G + PE H +
Sbjct: 315 ICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPP 374
Query: 68 -----KEPLEKFPD------DVNPVTKEKGGPRGPEPTRYGD---WER-KGR 104
KEP++ P+ + P K G +GP P R D WER KGR
Sbjct: 375 PEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGR 426
>gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens]
Length = 475
Score = 29.6 bits (65), Expect = 0.55
Identities = 21/85 (24%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 9 LLSWVSATAWRAARSPLLCHSLRKTSSSQGGKSELVKQSLKKPKLPEGRFDA-PEDSHLE 67
LL W AW +P SL ++ + K + + P + EG+ A +D+ +
Sbjct: 94 LLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEI---PTVLEGQGPANTQDATIA 150
Query: 68 KEPLEKFPDDVNPVTKEKGGPRGPE 92
+EP P D + K + P E
Sbjct: 151 QEPKNSEPQDPPNIEKPQEAPEYQE 175
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 29.3 bits (64), Expect = 0.71
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 11/85 (12%)
Query: 14 SATAWRAARSPLLCHSLRKTSSS-----QGGKSELVKQSLKKPKLPEGRFDAPEDSHLEK 68
S + + SP+ H L SSS QG S L+ SL KP + P S
Sbjct: 1147 SQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA 1206
Query: 69 EPLEKFPDD------VNPVTKEKGG 87
P++ P +P++ GG
Sbjct: 1207 SPMKPVPGTPPSSKAKSPISSGSGG 1231
>gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens]
Length = 479
Score = 28.9 bits (63), Expect = 0.93
Identities = 16/42 (38%), Positives = 21/42 (50%)
Query: 40 KSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPV 81
KS L+KQS+KKP E + + LE+ P P PV
Sbjct: 246 KSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV 287
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 28.1 bits (61), Expect = 1.6
Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 37 QGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKGGPR 89
QG K + ++K K E + DA +DS K+ EK D EKGG +
Sbjct: 136 QGKKDSKKGKDIEKGK--EEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAK 186
>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
Length = 1938
Score = 28.1 bits (61), Expect = 1.6
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 5/78 (6%)
Query: 23 SPLLCHSLRKTSSSQGGKSELVKQSLK-KPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPV 81
SP + S S+ GG + + L K PEG A +D+ +EK E D V+P
Sbjct: 1361 SPNIRRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPA 1420
Query: 82 TK----EKGGPRGPEPTR 95
+ EK PR E R
Sbjct: 1421 NQELHVEKPLPRSSEEWR 1438
>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
Length = 1960
Score = 28.1 bits (61), Expect = 1.6
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 5/78 (6%)
Query: 23 SPLLCHSLRKTSSSQGGKSELVKQSLK-KPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPV 81
SP + S S+ GG + + L K PEG A +D+ +EK E D V+P
Sbjct: 1361 SPNIRRSASSNSAEAGGDTVTLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPA 1420
Query: 82 TK----EKGGPRGPEPTR 95
+ EK PR E R
Sbjct: 1421 NQELHVEKPLPRSSEEWR 1438
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 28.1 bits (61), Expect = 1.6
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 4/49 (8%)
Query: 51 PKLPEGRF----DAPEDSHLEKEPLEKFPDDVNPVTKEKGGPRGPEPTR 95
P++P G F D PE + E+ P + +T ++G PR E +
Sbjct: 614 PRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEKAK 662
>gi|117320550 hypothetical protein LOC400566 [Homo sapiens]
Length = 433
Score = 28.1 bits (61), Expect = 1.6
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 10/62 (16%)
Query: 38 GGKSELVKQSLKKPKLPE-----GRFDAPEDSH-LEKEPLEKFPDDVNPVTKEKGGPRGP 91
GG SEL K+ +KK K + G+ D S L+ +PL D+ KE RGP
Sbjct: 75 GGASELAKRKVKKKKRKKKTKGSGKGDDKHQSQSLKSQPLSSSFHDILSPCKE----RGP 130
Query: 92 EP 93
+P
Sbjct: 131 KP 132
>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 27.3 bits (59), Expect = 2.7
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 30 LRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFP 75
L+++ S+GG S K SL K +P+GR L + + K P
Sbjct: 189 LQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVP 234
>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 27.3 bits (59), Expect = 2.7
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 30 LRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFP 75
L+++ S+GG S K SL K +P+GR L + + K P
Sbjct: 189 LQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVP 234
>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
sapiens]
Length = 622
Score = 27.3 bits (59), Expect = 2.7
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 30 LRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFP 75
L+++ S+GG S K SL K +P+GR L + + K P
Sbjct: 189 LQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVP 234
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 27.3 bits (59), Expect = 2.7
Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 5/50 (10%)
Query: 25 LLCHSLRKTS-----SSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKE 69
+L H +R+ SSQ +S +K S +PK+ + + +P+DS + E
Sbjct: 408 ILTHDIRERKEKGIPSSQTYESMAIKLSTPEPKIKKNNWQSPDDSDEDLE 457
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 26.9 bits (58), Expect = 3.5
Identities = 17/62 (27%), Positives = 27/62 (43%)
Query: 29 SLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKGGP 88
S++K S+ L S K +P+ R + + L K+ + FP K +G P
Sbjct: 210 SIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDSLKARGAP 269
Query: 89 RG 90
RG
Sbjct: 270 RG 271
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 26.9 bits (58), Expect = 3.5
Identities = 17/62 (27%), Positives = 27/62 (43%)
Query: 29 SLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKGGP 88
S++K S+ L S K +P+ R + + L K+ + FP K +G P
Sbjct: 211 SIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDSLKARGAP 270
Query: 89 RG 90
RG
Sbjct: 271 RG 272
>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
Length = 934
Score = 26.9 bits (58), Expect = 3.5
Identities = 17/62 (27%), Positives = 27/62 (43%)
Query: 29 SLRKTSSSQGGKSELVKQSLKKPKLPEGRFDAPEDSHLEKEPLEKFPDDVNPVTKEKGGP 88
S++K S+ L S K +P+ R + + L K+ + FP K +G P
Sbjct: 210 SIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDSLKARGAP 269
Query: 89 RG 90
RG
Sbjct: 270 RG 271
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 26.9 bits (58), Expect = 3.5
Identities = 11/29 (37%), Positives = 16/29 (55%)
Query: 61 PEDSHLEKEPLEKFPDDVNPVTKEKGGPR 89
P+DSHL + K D++ E+GG R
Sbjct: 517 PDDSHLNLDETTKLLQDLHEAQAERGGSR 545
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,631,235
Number of Sequences: 37866
Number of extensions: 284829
Number of successful extensions: 807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 772
Number of HSP's gapped (non-prelim): 72
length of query: 108
length of database: 18,247,518
effective HSP length: 78
effective length of query: 30
effective length of database: 15,293,970
effective search space: 458819100
effective search space used: 458819100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.