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Search of human proteins with 45593144
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens] 702 0.0
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 271 8e-73
gi|89257348 homeo box HB9 [Homo sapiens] 87 2e-17
gi|13273315 homeobox B4 [Homo sapiens] 87 2e-17
gi|226437602 NK1 homeobox 2 [Homo sapiens] 86 6e-17
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 85 8e-17
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 85 8e-17
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 85 8e-17
gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens] 84 1e-16
gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens] 84 1e-16
gi|148613882 homeobox A4 [Homo sapiens] 82 5e-16
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 82 5e-16
gi|157743259 H6 family homeobox 3 [Homo sapiens] 82 7e-16
gi|24497538 homeobox C4 [Homo sapiens] 82 7e-16
gi|24497540 homeobox C4 [Homo sapiens] 82 7e-16
gi|23397672 homeobox D4 [Homo sapiens] 82 9e-16
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens] 81 1e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens] 81 1e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens] 81 1e-15
gi|84570137 homeobox B3 [Homo sapiens] 80 4e-15
gi|4504469 homeobox B5 [Homo sapiens] 80 4e-15
gi|24497517 homeobox A5 [Homo sapiens] 79 5e-15
gi|5031761 homeobox A1 isoform a [Homo sapiens] 79 5e-15
gi|24497515 homeobox A3 isoform b [Homo sapiens] 79 8e-15
gi|24497513 homeobox A3 isoform a [Homo sapiens] 79 8e-15
gi|13562112 homeobox A3 isoform a [Homo sapiens] 79 8e-15
gi|27886557 msh homeobox 2 [Homo sapiens] 78 1e-14
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 78 1e-14
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 77 2e-14
gi|153218470 BarH-like homeobox 1 [Homo sapiens] 77 2e-14
>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
Length = 348
Score = 702 bits (1813), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP 60
MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP
Sbjct: 1 MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP 60
Query: 61 PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE 120
PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE
Sbjct: 61 PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE 120
Query: 121 AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRG 180
AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRG
Sbjct: 121 AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRG 180
Query: 181 QGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGS 240
QGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGS
Sbjct: 181 QGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGS 240
Query: 241 TTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRA 300
TTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRA
Sbjct: 241 TTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRA 300
Query: 301 KWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQARP 348
KWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQARP
Sbjct: 301 KWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQARP 348
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 271 bits (692), Expect = 8e-73
Identities = 187/360 (51%), Positives = 212/360 (58%), Gaps = 44/360 (12%)
Query: 17 GSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPPPPPALPQAALQPALPP 76
G TAFSIDSLIG PP P GH +YTGYPMFMPYRP+VLP AL A L LPP
Sbjct: 20 GPGTAFSIDSLIGPPP-PRSGHLLYTGYPMFMPYRPLVLPQ------ALAPAPLPAGLPP 72
Query: 77 AHPHHQIPS-LPTGFCSSLAQGM----ALTSTL--MATLPGGFSASPQHQEAAAARKFAP 129
P L FC+ L Q + ALT+ L A P F PQ AAAA A
Sbjct: 73 LAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYG-PQELAAAAAAAAAT 131
Query: 130 ----QPLPGG----GNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQ 181
P PGG G + E L A + +A+ +ET SL +
Sbjct: 132 AARNNPEPGGRRPEGGLEADELLPAREK-----VAEPPPPPPPHFSETFP-SLPAEGKVY 185
Query: 182 GKDESKVE---DDPKG---KEESFSLESDVDYSSDDNLTGQAAHKEEDP------GHALE 229
DE K+E DP G +EE +S+ D D + G A P G E
Sbjct: 186 SSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSLGTGAE 245
Query: 230 ETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEV 289
E P + AG T GK+RRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEV
Sbjct: 246 EGAPVT--AGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEV 303
Query: 290 QVKIWFQNRRAKWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQ-ARP 348
QVKIWFQNRRAKWKR+KAGN +S++GEP RNPKIVVPIPVHV+RFA+RSQHQQ+EQ ARP
Sbjct: 304 QVKIWFQNRRAKWKRIKAGNVSSRSGEPVRNPKIVVPIPVHVNRFAVRSQHQQMEQGARP 363
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 87.4 bits (215), Expect = 2e-17
Identities = 83/257 (32%), Positives = 104/257 (40%), Gaps = 23/257 (8%)
Query: 57 PPPPPPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASP 116
P PPA P L+ P P L C+ L + L + GG P
Sbjct: 60 PASSEPPAAPADRLRAESPSP------PRLLAAHCALLPKPGFLGAGGGGGGTGGGHGGP 113
Query: 117 QHQE---AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQAS 173
H AAAA A GG A L G L + +L A+
Sbjct: 114 HHHAHPGAAAAAAAAAAAAAAGG---LALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAA 170
Query: 174 LVGAVRGQGKDESKVEDDPKGKEESFSLE----SDVDYSSDDNLTGQAAHKEEDPGHALE 229
A+ GQ S +G + + + D L A G L
Sbjct: 171 AAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTA------GMILP 224
Query: 230 ETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEV 289
+ P + A S GK RR RTAFTS+QLLELE +F KYLS +R ++A +L L+E
Sbjct: 225 KMPDFNSQAQSNL-LGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTET 283
Query: 290 QVKIWFQNRRAKWKRVK 306
QVKIWFQNRR KWKR K
Sbjct: 284 QVKIWFQNRRMKWKRSK 300
>gi|13273315 homeobox B4 [Homo sapiens]
Length = 251
Score = 87.0 bits (214), Expect = 2e-17
Identities = 43/85 (50%), Positives = 56/85 (65%), Gaps = 8/85 (9%)
Query: 245 GKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWK- 303
G+ +R RTA+T +Q+LELEKEFH +YL+ R +IAHAL LSE Q+KIWFQNRR KWK
Sbjct: 160 GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKK 219
Query: 304 -------RVKAGNANSKTGEPSRNP 321
++++G A G P P
Sbjct: 220 DHKLPNTKIRSGGAAGSAGGPPGRP 244
Score = 34.7 bits (78), Expect = 0.13
Identities = 15/40 (37%), Positives = 19/40 (47%)
Query: 56 PPPPPPPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLA 95
PPPPPPPP P L P P P + P C +++
Sbjct: 75 PPPPPPPPPPPPPGLSPRAPAPPPAGALLPEPGQRCEAVS 114
Score = 32.7 bits (73), Expect = 0.49
Identities = 15/29 (51%), Positives = 16/29 (55%)
Query: 49 PYRPVVLPPPPPPPPALPQAALQPALPPA 77
P P PPPPPPPP + PA PPA
Sbjct: 71 PGPPPPPPPPPPPPPPPGLSPRAPAPPPA 99
Score = 29.3 bits (64), Expect = 5.5
Identities = 12/24 (50%), Positives = 12/24 (50%)
Query: 56 PPPPPPPPALPQAALQPALPPAHP 79
P PPPPPP P P L P P
Sbjct: 71 PGPPPPPPPPPPPPPPPGLSPRAP 94
>gi|226437602 NK1 homeobox 2 [Homo sapiens]
Length = 310
Score = 85.5 bits (210), Expect = 6e-17
Identities = 73/230 (31%), Positives = 108/230 (46%), Gaps = 31/230 (13%)
Query: 104 LMATLPGGFSASPQHQEAAAA-------RKFAPQPLPGGGNFDK-AEALQADAEDGKGFL 155
++A GG A+P H + + + +KF LP + A A+ E GK
Sbjct: 1 MLAWQDGGAKAAPSHHKISFSVLDILDPQKFTRAALPAVRPAPREARKSLAEVEAGKDAS 60
Query: 156 AKEGSLLAFSAAETVQASLVGAVRGQGKDESKVEDD--------PKGKEESFSLESDVDY 207
+++ ET A+ GA + + S+ E++ P+ +E + L +
Sbjct: 61 SRD----PVRQLETPDAAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLAR 116
Query: 208 SSDDNLTGQAAHKE-EDPGHALEETPPSSGAAGSTT--------STGKNRRRRTAFTSEQ 258
S D A+ + ED G +PP G+ GS + K RR RTAFT EQ
Sbjct: 117 SPDAPAGALASGEPCEDGGGGPVRSPP--GSPGSPRPRRRRLEPNCAKPRRARTAFTYEQ 174
Query: 259 LLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAG 308
L+ LE +F +YLS+ ER +A +L L+E QVKIWFQNRR KWK+ G
Sbjct: 175 LVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPG 224
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 85.1 bits (209), Expect = 8e-17
Identities = 43/84 (51%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 233 PSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVK 292
P GS + +GK RR RTAFT EQL+ LE +F +YLS+ ER +A +L L+E QVK
Sbjct: 648 PKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVK 707
Query: 293 IWFQNRRAKWKRVKAG-NANSKTG 315
IWFQNRR KWK+ G + ++ TG
Sbjct: 708 IWFQNRRTKWKKQNPGADTSAPTG 731
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 85.1 bits (209), Expect = 8e-17
Identities = 43/84 (51%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 233 PSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVK 292
P GS + +GK RR RTAFT EQL+ LE +F +YLS+ ER +A +L L+E QVK
Sbjct: 83 PKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVK 142
Query: 293 IWFQNRRAKWKRVKAG-NANSKTG 315
IWFQNRR KWK+ G + ++ TG
Sbjct: 143 IWFQNRRTKWKKQNPGADTSAPTG 166
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 85.1 bits (209), Expect = 8e-17
Identities = 43/84 (51%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 233 PSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVK 292
P GS + +GK RR RTAFT EQL+ LE +F +YLS+ ER +A +L L+E QVK
Sbjct: 245 PKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVK 304
Query: 293 IWFQNRRAKWKRVKAG-NANSKTG 315
IWFQNRR KWK+ G + ++ TG
Sbjct: 305 IWFQNRRTKWKKQNPGADTSAPTG 328
>gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens]
Length = 139
Score = 84.3 bits (207), Expect = 1e-16
Identities = 48/108 (44%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Query: 210 DDNLTGQAAHK-EEDPGHALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHC 268
D + G A++ E+ +E+ + G + K R+ RTAFT EQL ELE EF
Sbjct: 18 DYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAH 77
Query: 269 KKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGE 316
YL+ R +IA L LSE QVK+WFQNRR KWKRVK G S G+
Sbjct: 78 HNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ 125
>gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens]
Length = 254
Score = 84.3 bits (207), Expect = 1e-16
Identities = 48/108 (44%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Query: 210 DDNLTGQAAHK-EEDPGHALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHC 268
D + G A++ E+ +E+ + G + K R+ RTAFT EQL ELE EF
Sbjct: 133 DYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAH 192
Query: 269 KKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGE 316
YL+ R +IA L LSE QVK+WFQNRR KWKRVK G S G+
Sbjct: 193 HNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQ 240
>gi|148613882 homeobox A4 [Homo sapiens]
Length = 320
Score = 82.4 bits (202), Expect = 5e-16
Identities = 39/68 (57%), Positives = 50/68 (73%)
Query: 237 AAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQ 296
A + + G+ +R RTA+T +Q+LELEKEFH +YL+ R +IAH L LSE QVKIWFQ
Sbjct: 205 AVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQ 264
Query: 297 NRRAKWKR 304
NRR KWK+
Sbjct: 265 NRRMKWKK 272
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 82.4 bits (202), Expect = 5e-16
Identities = 49/121 (40%), Positives = 68/121 (56%), Gaps = 5/121 (4%)
Query: 215 GQAAHKEEDPGHALEETPPSSGAA--GSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYL 272
G AA EE L E P ++G G G+ ++ RT F+ Q+ +LE F K+YL
Sbjct: 171 GPAAGTEE--ASELAEVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYL 228
Query: 273 SLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEPSRNPKIV-VPIPVHV 331
S ER+ +A +L+L+E QVKIWFQNRR KWKR A + + P ++V VP+ H
Sbjct: 229 SSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHE 288
Query: 332 S 332
S
Sbjct: 289 S 289
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 82.0 bits (201), Expect = 7e-16
Identities = 89/320 (27%), Positives = 127/320 (39%), Gaps = 72/320 (22%)
Query: 57 PPPPPPPALPQAALQPALPPAHPHHQIPSLP-----TGFCSSLAQGMALTSTLMAT---- 107
PPPPPPPA ++ HH+ P P T F + A A + A
Sbjct: 18 PPPPPPPAPKESPFSIKNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGAL 77
Query: 108 --------------------LPGGFSASPQHQEAAAARKFAPQPL-PGGGNFDKAEALQA 146
+P A P H + + P L P GG+ + EA +
Sbjct: 78 EGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEK 137
Query: 147 DAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQGKDESKVEDDPKGKEESFSLESDVD 206
L ++ S + + ++ + L D E D K +E ESD +
Sbjct: 138 A-------LLRDSSPASGTDRDSPEPLLKA-------DPDHKELDSKSPDEIILEESDSE 183
Query: 207 YSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGSTTSTG---------------KNRRRR 251
S + G+AA PG A S GAA +T + ++ R
Sbjct: 184 ESKKE---GEAA-----PGAA----GASVGAAAATPGAEDWKKGAESPEKKPACRKKKTR 231
Query: 252 TAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNAN 311
T F+ Q+ +LE F K+YLS +ER+ +A +L L+E QVKIWFQNRR KWKR A
Sbjct: 232 TVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELE 291
Query: 312 SKTGEPSRNPKIV-VPIPVH 330
+ + +IV VPI H
Sbjct: 292 AANLSHAAAQRIVRVPILYH 311
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 82.0 bits (201), Expect = 7e-16
Identities = 37/60 (61%), Positives = 48/60 (80%)
Query: 245 GKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 304
G+ +R RTA+T +Q+LELEKEFH +YL+ R +IAH+L LSE Q+KIWFQNRR KWK+
Sbjct: 154 GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213
Score = 29.3 bits (64), Expect = 5.5
Identities = 25/104 (24%), Positives = 36/104 (34%), Gaps = 10/104 (9%)
Query: 32 PQPSPGHFVYTGYPMFMPYRPVVLPPPPPPP---------PALPQAALQPALPPAHPHHQ 82
P+ SP ++ T F + + PPPPP P +L PA H
Sbjct: 30 PEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHH 89
Query: 83 IPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQEAAAARK 126
P C A S A P +P H +AA+++
Sbjct: 90 HPEKSQSLCEPAPLSGASASPSPAP-PACSQPAPDHPSSAASKQ 132
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 82.0 bits (201), Expect = 7e-16
Identities = 37/60 (61%), Positives = 48/60 (80%)
Query: 245 GKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 304
G+ +R RTA+T +Q+LELEKEFH +YL+ R +IAH+L LSE Q+KIWFQNRR KWK+
Sbjct: 154 GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213
Score = 29.3 bits (64), Expect = 5.5
Identities = 25/104 (24%), Positives = 36/104 (34%), Gaps = 10/104 (9%)
Query: 32 PQPSPGHFVYTGYPMFMPYRPVVLPPPPPPP---------PALPQAALQPALPPAHPHHQ 82
P+ SP ++ T F + + PPPPP P +L PA H
Sbjct: 30 PEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHH 89
Query: 83 IPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQEAAAARK 126
P C A S A P +P H +AA+++
Sbjct: 90 HPEKSQSLCEPAPLSGASASPSPAP-PACSQPAPDHPSSAASKQ 132
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 81.6 bits (200), Expect = 9e-16
Identities = 37/60 (61%), Positives = 47/60 (78%)
Query: 245 GKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 304
G+ +R RTA+T +Q+LELEKEFH +YL+ R +IAH L LSE Q+KIWFQNRR KWK+
Sbjct: 152 GEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKK 211
>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 81.3 bits (199), Expect = 1e-15
Identities = 64/174 (36%), Positives = 84/174 (48%), Gaps = 28/174 (16%)
Query: 146 ADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQGKDESKVEDD--PKGKEESFSLES 203
+DA D G A + S L S AE +E ED P+ +E + L
Sbjct: 90 SDARDAAGPGAGQASPLEGSEAE---------------EEEDAEDPRRPRLRERAARLLP 134
Query: 204 DVDYSSDDNLTGQAAHKE-EDPGHALEETPPSSGAAGSTT--------STGKNRRRRTAF 254
+ S D A+ + ED G +PP G+ GS + K RR RTAF
Sbjct: 135 GLARSPDAPAGALASGEPCEDGGGGPVRSPP--GSPGSPRPRRRRLEPNCAKPRRARTAF 192
Query: 255 TSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAG 308
T EQL+ LE +F +YLS+ ER +A +L L+E QVKIWFQNRR KWK+ G
Sbjct: 193 TYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPG 246
>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 81.3 bits (199), Expect = 1e-15
Identities = 64/174 (36%), Positives = 84/174 (48%), Gaps = 28/174 (16%)
Query: 146 ADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQGKDESKVEDD--PKGKEESFSLES 203
+DA D G A + S L S AE +E ED P+ +E + L
Sbjct: 90 SDARDAAGPGAGQASPLEGSEAE---------------EEEDAEDPRRPRLRERAARLLP 134
Query: 204 DVDYSSDDNLTGQAAHKE-EDPGHALEETPPSSGAAGSTT--------STGKNRRRRTAF 254
+ S D A+ + ED G +PP G+ GS + K RR RTAF
Sbjct: 135 GLARSPDAPAGALASGEPCEDGGGGPVRSPP--GSPGSPRPRRRRLEPNCAKPRRARTAF 192
Query: 255 TSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAG 308
T EQL+ LE +F +YLS+ ER +A +L L+E QVKIWFQNRR KWK+ G
Sbjct: 193 TYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPG 246
>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 81.3 bits (199), Expect = 1e-15
Identities = 64/174 (36%), Positives = 84/174 (48%), Gaps = 28/174 (16%)
Query: 146 ADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQGKDESKVEDD--PKGKEESFSLES 203
+DA D G A + S L S AE +E ED P+ +E + L
Sbjct: 90 SDARDAAGPGAGQASPLEGSEAE---------------EEEDAEDPRRPRLRERAARLLP 134
Query: 204 DVDYSSDDNLTGQAAHKE-EDPGHALEETPPSSGAAGSTT--------STGKNRRRRTAF 254
+ S D A+ + ED G +PP G+ GS + K RR RTAF
Sbjct: 135 GLARSPDAPAGALASGEPCEDGGGGPVRSPP--GSPGSPRPRRRRLEPNCAKPRRARTAF 192
Query: 255 TSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAG 308
T EQL+ LE +F +YLS+ ER +A +L L+E QVKIWFQNRR KWK+ G
Sbjct: 193 TYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPG 246
>gi|84570137 homeobox B3 [Homo sapiens]
Length = 431
Score = 79.7 bits (195), Expect = 4e-15
Identities = 44/91 (48%), Positives = 59/91 (64%), Gaps = 10/91 (10%)
Query: 229 EETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSE 288
+++PP S A+ +R RTA+TS QL+ELEKEFH +YL R ++A+ L LSE
Sbjct: 179 DKSPPGSAAS---------KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSE 229
Query: 289 VQVKIWFQNRRAKWKR-VKAGNANSKTGEPS 318
Q+KIWFQNRR K+K+ KA S +G PS
Sbjct: 230 RQIKIWFQNRRMKYKKDQKAKGLASSSGGPS 260
>gi|4504469 homeobox B5 [Homo sapiens]
Length = 269
Score = 79.7 bits (195), Expect = 4e-15
Identities = 50/122 (40%), Positives = 65/122 (53%), Gaps = 5/122 (4%)
Query: 184 DESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGSTTS 243
DE+ +P+ S S + T AA + + P + P S
Sbjct: 134 DEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTP----QIFPWMRKLHISHDM 189
Query: 244 TGKN-RRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKW 302
TG + +R RTA+T Q LELEKEFH +YL+ R +IAHAL LSE Q+KIWFQNRR KW
Sbjct: 190 TGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 249
Query: 303 KR 304
K+
Sbjct: 250 KK 251
>gi|24497517 homeobox A5 [Homo sapiens]
Length = 270
Score = 79.3 bits (194), Expect = 5e-15
Identities = 37/59 (62%), Positives = 45/59 (76%)
Query: 246 KNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 304
+ +R RTA+T Q LELEKEFH +YL+ R +IAHAL LSE Q+KIWFQNRR KWK+
Sbjct: 194 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 252
>gi|5031761 homeobox A1 isoform a [Homo sapiens]
Length = 335
Score = 79.3 bits (194), Expect = 5e-15
Identities = 39/77 (50%), Positives = 51/77 (66%)
Query: 228 LEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLS 287
++ PP +G G G+ RT FT++QL ELEKEFH KYL+ R +IA +L+L+
Sbjct: 210 VKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLN 269
Query: 288 EVQVKIWFQNRRAKWKR 304
E QVKIWFQNRR K K+
Sbjct: 270 ETQVKIWFQNRRMKQKK 286
>gi|24497515 homeobox A3 isoform b [Homo sapiens]
Length = 285
Score = 78.6 bits (192), Expect = 8e-15
Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Query: 220 KEEDPGHALEETPPSSG--AAGSTTSTGK--NRRRRTAFTSEQLLELEKEFHCKKYLSLT 275
KE + + SSG AG + G+ ++R RTA+TS QL+ELEKEFH +YL
Sbjct: 2 KESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRP 61
Query: 276 ERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGN---ANSKTGEPSRNP 321
R ++A+ L L+E Q+KIWFQNRR K+K+ + G +S PSR+P
Sbjct: 62 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP 110
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 78.6 bits (192), Expect = 8e-15
Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Query: 220 KEEDPGHALEETPPSSG--AAGSTTSTGK--NRRRRTAFTSEQLLELEKEFHCKKYLSLT 275
KE + + SSG AG + G+ ++R RTA+TS QL+ELEKEFH +YL
Sbjct: 160 KESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRP 219
Query: 276 ERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGN---ANSKTGEPSRNP 321
R ++A+ L L+E Q+KIWFQNRR K+K+ + G +S PSR+P
Sbjct: 220 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP 268
Score = 32.7 bits (73), Expect = 0.49
Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 9/66 (13%)
Query: 28 IGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPPPPPALPQ-AALQPALPP----AHPHHQ 82
+ +PP P G P P P PP P PP PQ A PA PP A P
Sbjct: 75 LSAPPSQPPS----LGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQN 130
Query: 83 IPSLPT 88
+ PT
Sbjct: 131 ASNNPT 136
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 78.6 bits (192), Expect = 8e-15
Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Query: 220 KEEDPGHALEETPPSSG--AAGSTTSTGK--NRRRRTAFTSEQLLELEKEFHCKKYLSLT 275
KE + + SSG AG + G+ ++R RTA+TS QL+ELEKEFH +YL
Sbjct: 160 KESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRP 219
Query: 276 ERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGN---ANSKTGEPSRNP 321
R ++A+ L L+E Q+KIWFQNRR K+K+ + G +S PSR+P
Sbjct: 220 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP 268
Score = 32.7 bits (73), Expect = 0.49
Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 9/66 (13%)
Query: 28 IGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPPPPPALPQ-AALQPALPP----AHPHHQ 82
+ +PP P G P P P PP P PP PQ A PA PP A P
Sbjct: 75 LSAPPSQPPS----LGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQN 130
Query: 83 IPSLPT 88
+ PT
Sbjct: 131 ASNNPT 136
>gi|27886557 msh homeobox 2 [Homo sapiens]
Length = 267
Score = 77.8 bits (190), Expect = 1e-14
Identities = 44/113 (38%), Positives = 66/113 (58%), Gaps = 8/113 (7%)
Query: 222 EDPGHALEETPPSSGAAGSTTSTGK---NRRRRTAFTSEQLLELEKEFHCKKYLSLTERS 278
++PG +PP + +T + K NR+ RT FT+ QLL LE++F K+YLS+ ER+
Sbjct: 117 QEPGRY---SPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERA 173
Query: 279 QIAHALKLSEVQVKIWFQNRRAKWKRVKAGNAN--SKTGEPSRNPKIVVPIPV 329
+ + +L L+E QVKIWFQNRRAK KR++ +P +P P+
Sbjct: 174 EFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPI 226
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 77.8 bits (190), Expect = 1e-14
Identities = 85/325 (26%), Positives = 128/325 (39%), Gaps = 60/325 (18%)
Query: 10 MMMQRPLGSSTAFSIDSLIGSPPQPSPG----HFVYTGYPMFMPYRPVVLPPP------- 58
M M+ GSS F ID+++ S SPG F G +R P P
Sbjct: 1 MTMEGASGSS--FGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTV 58
Query: 59 ---PPPPPALPQAALQPAL---PPAHPHH----QIPSLPTGFCSSLAQGMALTSTLMATL 108
P P ++ +P L H HH Q P P + Q +
Sbjct: 59 GTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPL---------- 108
Query: 109 PGGFSASPQHQEAAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKE--GSLLAFSA 166
PQ Q+ ++ P P G+ A A FL K+ G +A
Sbjct: 109 -------PQQQQPLPPQQPPPPPPQQLGS-----AASAPRTSTSSFLIKDILGDSKPLAA 156
Query: 167 AETVQASLVGAVRGQGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGH 226
S+ ++ + V + + K E ++ +D +D+ + H ++ G
Sbjct: 157 CAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLD-KREDSQSDIKCHGTKEEGD 215
Query: 227 ----ALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAH 282
+ E+PP K R+ RTAF+ QL +LE+ F +KYLS+ +R +A
Sbjct: 216 REITSSRESPP--------VRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAA 267
Query: 283 ALKLSEVQVKIWFQNRRAKWKRVKA 307
AL L++ QVK W+QNRR KWKR A
Sbjct: 268 ALNLTDTQVKTWYQNRRTKWKRQTA 292
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 77.4 bits (189), Expect = 2e-14
Identities = 41/101 (40%), Positives = 59/101 (58%), Gaps = 13/101 (12%)
Query: 220 KEEDPGHALEE-TPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERS 278
K+ GH + TPP K ++ RT+FT Q+ ELEK FH +KYL+ ER+
Sbjct: 185 KDRFTGHPYQNRTPP------------KKKKPRTSFTRLQICELEKRFHRQKYLASAERA 232
Query: 279 QIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEPSR 319
+A ALK+++ QVK WFQNRR KW+R A ++ + +R
Sbjct: 233 ALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANR 273
>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
Length = 254
Score = 77.4 bits (189), Expect = 2e-14
Identities = 41/95 (43%), Positives = 55/95 (57%), Gaps = 2/95 (2%)
Query: 234 SSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKI 293
++G T K RR RT FT QL+ LEK F +KYLS +R +A +L LS++QVK
Sbjct: 129 AAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKT 188
Query: 294 WFQNRRAKWKRV--KAGNANSKTGEPSRNPKIVVP 326
W+QNRR KWK++ + G S T R K +P
Sbjct: 189 WYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIP 223
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,152,260
Number of Sequences: 37866
Number of extensions: 1079551
Number of successful extensions: 18727
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 706
Number of HSP's successfully gapped in prelim test: 599
Number of HSP's that attempted gapping in prelim test: 8703
Number of HSP's gapped (non-prelim): 5515
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.