Guide to the Human Genome
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Search of human proteins with 13236585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13236585 fibronectin type III and SPRY domain containing 1
[Homo sapiens]
         (496 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13236585 fibronectin type III and SPRY domain containing 1 [H...   992   0.0  
gi|89886468 fibronectin type III and SPRY domain containing 1-li...   615   e-176
gi|223718222 fibronectin type III and SPRY domain containing 1-l...   612   e-175
gi|148833499 midline 1 [Homo sapiens]                                 210   2e-54
gi|4557753 midline 1 [Homo sapiens]                                   210   2e-54
gi|15451852 midline 1 [Homo sapiens]                                  210   2e-54
gi|223890259 midline 2 isoform 2 [Homo sapiens]                       199   5e-51
gi|223890257 midline 2 isoform 1 [Homo sapiens]                       191   1e-48
gi|47174859 tripartite motif-containing 46 [Homo sapiens]             117   2e-26
gi|13994289 fibronectin type III and SPRY domain containing 1-li...   112   6e-25
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]   101   1e-21
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             97   3e-20
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]       86   8e-17
gi|55741632 fibronectin type III and SPRY domain containing 2 [H...    79   9e-15
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 76   8e-14
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]        76   8e-14
gi|46409324 SPRY domain containing 4 [Homo sapiens]                    69   1e-11
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...    65   1e-10
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...    65   1e-10
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...    65   1e-10
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]       65   2e-10
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              63   7e-10
gi|38679905 tripartite motif-containing 65 [Homo sapiens]              56   7e-08
gi|63054855 erythroblast membrane-associated protein precursor [...    56   7e-08
gi|19923536 erythroblast membrane-associated protein precursor [...    56   7e-08
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]            56   9e-08
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]           55   2e-07
gi|22749269 ring finger protein 129 [Homo sapiens]                     54   3e-07
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]            54   3e-07
gi|217035095 tripartite motif-containing 62 [Homo sapiens]             53   6e-07

>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
           sapiens]
          Length = 496

 Score =  992 bits (2565), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE 60
           MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE
Sbjct: 1   MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE 60

Query: 61  LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI 120
           LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI
Sbjct: 61  LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI 120

Query: 121 KDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADN 180
           KDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADN
Sbjct: 121 KDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADN 180

Query: 181 CVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMK 240
           CVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMK
Sbjct: 181 CVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMK 240

Query: 241 YMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDI 300
           YMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDI
Sbjct: 241 YMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDI 300

Query: 301 KAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEV 360
           KAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEV
Sbjct: 301 KAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEV 360

Query: 361 RYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPD 420
           RYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPD
Sbjct: 361 RYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPD 420

Query: 421 CLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRC 480
           CLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRC
Sbjct: 421 CLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRC 480

Query: 481 LQKRGSATSSSNTSLT 496
           LQKRGSATSSSNTSLT
Sbjct: 481 LQKRGSATSSSNTSLT 496


>gi|89886468 fibronectin type III and SPRY domain containing 1-like
           isoform 1 [Homo sapiens]
          Length = 498

 Score =  615 bits (1586), Expect = e-176
 Identities = 300/495 (60%), Positives = 388/495 (78%), Gaps = 3/495 (0%)

Query: 1   MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE 60
           M+ Q+EAL++II TLA KN+EIQ+FI +L   L  V+ NS+ +  +L+ EF SL+S+L+E
Sbjct: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60

Query: 61  LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI 120
           +KE M+  IKQ++A ++ ELQ+Q++ C  ALE+SEELLE A ++L   + E+F +AA+QI
Sbjct: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQI 120

Query: 121 KDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADN 180
           KD VTMA AFRLSLK KVSDNM+HLMVDF+QERQMLQ LKFLPVP AP ID  E LVADN
Sbjct: 121 KDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADN 180

Query: 181 CVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMK 240
            VT+ WRMP+ED+KIDH++LE+R+TNF+G PR+K+++ W +I+ I+ TEYTL+GLKFD K
Sbjct: 181 SVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSK 240

Query: 241 YMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDI 300
           YMNFRV+ACNKAVAGE+S+PVTLET A  F LD S+SH NL+V+D  VEWD  GGK Q+ 
Sbjct: 241 YMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQES 300

Query: 301 KAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEV 360
           K + K+ KGR+ +P  SP R T    R P+ RG RDRFT ESYTVLGDT I+ G+HYWEV
Sbjct: 301 KIKGKENKGRSGTP--SPKR-TSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEV 357

Query: 361 RYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPD 420
           + + D K++ VGVAY++LG+F+QLGKT  SWC+HVNNWLQ +F AKH NKVK LD  VP+
Sbjct: 358 KAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPE 417

Query: 421 CLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRC 480
            +GV CDF  G LSFY+A +KQ+L++FKT+FTQP+LP F VWCG   ++TG+QVPSAVR 
Sbjct: 418 KIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRT 477

Query: 481 LQKRGSATSSSNTSL 495
           LQK  +  + S +SL
Sbjct: 478 LQKSENGMTGSASSL 492


>gi|223718222 fibronectin type III and SPRY domain containing 1-like
           isoform 3 [Homo sapiens]
          Length = 530

 Score =  612 bits (1578), Expect = e-175
 Identities = 299/492 (60%), Positives = 386/492 (78%), Gaps = 3/492 (0%)

Query: 4   QREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKE 63
           Q+EAL++II TLA KN+EIQ+FI +L   L  V+ NS+ +  +L+ EF SL+S+L+E+KE
Sbjct: 36  QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95

Query: 64  GMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDG 123
            M+  IKQ++A ++ ELQ+Q++ C  ALE+SEELLE A ++L   + E+F +AA+QIKD 
Sbjct: 96  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 155

Query: 124 VTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADNCVT 183
           VTMA AFRLSLK KVSDNM+HLMVDF+QERQMLQ LKFLPVP AP ID  E LVADN VT
Sbjct: 156 VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT 215

Query: 184 LVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMN 243
           + WRMP+ED+KIDH++LE+R+TNF+G PR+K+++ W +I+ I+ TEYTL+GLKFD KYMN
Sbjct: 216 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 275

Query: 244 FRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKAR 303
           FRV+ACNKAVAGE+S+PVTLET A  F LD S+SH NL+V+D  VEWD  GGK Q+ K +
Sbjct: 276 FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK 335

Query: 304 EKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRYE 363
            K+ KGR+ +P  SP R T    R P+ RG RDRFT ESYTVLGDT I+ G+HYWEV+ +
Sbjct: 336 GKENKGRSGTP--SPKR-TSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQ 392

Query: 364 PDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPDCLG 423
            D K++ VGVAY++LG+F+QLGKT  SWC+HVNNWLQ +F AKH NKVK LD  VP+ +G
Sbjct: 393 KDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIG 452

Query: 424 VHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQK 483
           V CDF  G LSFY+A +KQ+L++FKT+FTQP+LP F VWCG   ++TG+QVPSAVR LQK
Sbjct: 453 VFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQK 512

Query: 484 RGSATSSSNTSL 495
             +  + S +SL
Sbjct: 513 SENGMTGSASSL 524


>gi|148833499 midline 1 [Homo sapiens]
          Length = 667

 Score =  210 bits (535), Expect = 2e-54
 Identities = 146/493 (29%), Positives = 244/493 (49%), Gaps = 55/493 (11%)

Query: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
           ++ ++ L   +  L  +N E+++ +  L Q   +VE N+++ +  L  E   L  ++++ 
Sbjct: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276

Query: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
           ++ +  KIK+ +  R  +L  Q+A C + +E S  L+  A  +L+  D   F Q AK I 
Sbjct: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336

Query: 122 DGVTMAPAFRLSL--KAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179
           + V+MA A    L  +  ++D      +DF++E+++L+ L +L  P+ P I       + 
Sbjct: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396

Query: 180 NCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRL----KEDQPWMVIEGIRQTEYTLTGL 235
           + +T+ W   DE S +  Y L+Y  T F G   +         WM++  I+Q  YT+ GL
Sbjct: 397 DTITVHWTSDDEFSVVS-YELQY--TIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453

Query: 236 KFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRV--DDLSVEWDAM 293
           +   KY+ F VKA N+A     SEP  L+T +  F+LD  ++H+ L+V  D+L+VE D  
Sbjct: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511

Query: 294 GGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAE-SYTVLGDTLID 352
             K           K  T                        +RFT++ SY V G+  ID
Sbjct: 512 SSK-----------KSHTP-----------------------ERFTSQGSYGVAGNVFID 537

Query: 353 GGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASW--CLHVNNWLQVSFTAKHANK 410
            G HYWEV     S  + +G+AY+S  + E +GK +ASW  C   NNW+       ++ +
Sbjct: 538 SGRHYWEVVIS-GSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV----VRHNSKE 592

Query: 411 VKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTT 470
           + +  AP    +G+  D+  G ++FY+A     L+TF   F QP+ P FTVW     + T
Sbjct: 593 IPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIIT 652

Query: 471 GLQVPSAVRCLQK 483
           GL +P  + C ++
Sbjct: 653 GLPIPDHLDCTEQ 665


>gi|4557753 midline 1 [Homo sapiens]
          Length = 667

 Score =  210 bits (535), Expect = 2e-54
 Identities = 146/493 (29%), Positives = 244/493 (49%), Gaps = 55/493 (11%)

Query: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
           ++ ++ L   +  L  +N E+++ +  L Q   +VE N+++ +  L  E   L  ++++ 
Sbjct: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276

Query: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
           ++ +  KIK+ +  R  +L  Q+A C + +E S  L+  A  +L+  D   F Q AK I 
Sbjct: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336

Query: 122 DGVTMAPAFRLSL--KAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179
           + V+MA A    L  +  ++D      +DF++E+++L+ L +L  P+ P I       + 
Sbjct: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396

Query: 180 NCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRL----KEDQPWMVIEGIRQTEYTLTGL 235
           + +T+ W   DE S +  Y L+Y  T F G   +         WM++  I+Q  YT+ GL
Sbjct: 397 DTITVHWTSDDEFSVVS-YELQY--TIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453

Query: 236 KFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRV--DDLSVEWDAM 293
           +   KY+ F VKA N+A     SEP  L+T +  F+LD  ++H+ L+V  D+L+VE D  
Sbjct: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511

Query: 294 GGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAE-SYTVLGDTLID 352
             K           K  T                        +RFT++ SY V G+  ID
Sbjct: 512 SSK-----------KSHTP-----------------------ERFTSQGSYGVAGNVFID 537

Query: 353 GGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASW--CLHVNNWLQVSFTAKHANK 410
            G HYWEV     S  + +G+AY+S  + E +GK +ASW  C   NNW+       ++ +
Sbjct: 538 SGRHYWEVVIS-GSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV----VRHNSKE 592

Query: 411 VKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTT 470
           + +  AP    +G+  D+  G ++FY+A     L+TF   F QP+ P FTVW     + T
Sbjct: 593 IPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIIT 652

Query: 471 GLQVPSAVRCLQK 483
           GL +P  + C ++
Sbjct: 653 GLPIPDHLDCTEQ 665


>gi|15451852 midline 1 [Homo sapiens]
          Length = 667

 Score =  210 bits (535), Expect = 2e-54
 Identities = 146/493 (29%), Positives = 244/493 (49%), Gaps = 55/493 (11%)

Query: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
           ++ ++ L   +  L  +N E+++ +  L Q   +VE N+++ +  L  E   L  ++++ 
Sbjct: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276

Query: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
           ++ +  KIK+ +  R  +L  Q+A C + +E S  L+  A  +L+  D   F Q AK I 
Sbjct: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336

Query: 122 DGVTMAPAFRLSL--KAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179
           + V+MA A    L  +  ++D      +DF++E+++L+ L +L  P+ P I       + 
Sbjct: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396

Query: 180 NCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRL----KEDQPWMVIEGIRQTEYTLTGL 235
           + +T+ W   DE S +  Y L+Y  T F G   +         WM++  I+Q  YT+ GL
Sbjct: 397 DTITVHWTSDDEFSVVS-YELQY--TIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453

Query: 236 KFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRV--DDLSVEWDAM 293
           +   KY+ F VKA N+A     SEP  L+T +  F+LD  ++H+ L+V  D+L+VE D  
Sbjct: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511

Query: 294 GGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAE-SYTVLGDTLID 352
             K           K  T                        +RFT++ SY V G+  ID
Sbjct: 512 SSK-----------KSHTP-----------------------ERFTSQGSYGVAGNVFID 537

Query: 353 GGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASW--CLHVNNWLQVSFTAKHANK 410
            G HYWEV     S  + +G+AY+S  + E +GK +ASW  C   NNW+       ++ +
Sbjct: 538 SGRHYWEVVIS-GSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV----VRHNSKE 592

Query: 411 VKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTT 470
           + +  AP    +G+  D+  G ++FY+A     L+TF   F QP+ P FTVW     + T
Sbjct: 593 IPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIIT 652

Query: 471 GLQVPSAVRCLQK 483
           GL +P  + C ++
Sbjct: 653 GLPIPDHLDCTEQ 665


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score =  199 bits (506), Expect = 5e-51
 Identities = 144/484 (29%), Positives = 234/484 (48%), Gaps = 47/484 (9%)

Query: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
           E+ ++ L   +  L  +N E+++ +  L Q+   VE N+A  +  L  E   L  ++++ 
Sbjct: 237 EKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQR 296

Query: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
           K+ + +KIK+ +  +  +L  Q+A C + LE S  L+  A   L+  D   F Q+AK I 
Sbjct: 297 KQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIA 356

Query: 122 DGVTMAPAFRLSLKAKV--SDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179
           + V MA A    L   +  +D   +  +DF++E+++L+ L +L  P+ P I       + 
Sbjct: 357 ERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASH 416

Query: 180 NCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRL----KEDQPWMVIEGIRQTEYTLTGL 235
           + +T+ W + D++  I  Y L+Y  T F G             WM++  I+Q  YT+ GL
Sbjct: 417 DTITVHW-ISDDEFSISSYELQY--TIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGL 473

Query: 236 KFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGG 295
           +   +Y+ F VKA N+A     SEP  L+T +  F+LD   +H+ L++ +          
Sbjct: 474 QSGTRYI-FIVKAINQA-GSRNSEPTRLKTNSQPFKLDPKMTHKKLKISN---------- 521

Query: 296 KVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGE 355
              D    EKD          S  + + +P+R  SG G         Y   G+  ID G 
Sbjct: 522 ---DGLQMEKD---------ESSLKKSHTPERF-SGTG--------CYGAAGNIFIDSGC 560

Query: 356 HYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLD 415
           HYWEV     S  + +G+AY+S  + E +GK A+SW   V +    +F  +H NK  ++D
Sbjct: 561 HYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKNASSW---VFSRCNSNFVVRHNNKEMLVD 616

Query: 416 APVP-DCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQV 474
            P     LGV  D+   +LSFY+      LHTF   F  P+ P FT+W  S  + +GL  
Sbjct: 617 VPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPA 676

Query: 475 PSAV 478
           P  +
Sbjct: 677 PDFI 680


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score =  191 bits (485), Expect = 1e-48
 Identities = 145/512 (28%), Positives = 237/512 (46%), Gaps = 73/512 (14%)

Query: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
           E+ ++ L   +  L  +N E+++ +  L Q+   VE N+A  +  L  E   L  ++++ 
Sbjct: 237 EKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQR 296

Query: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
           K+ + +KIK+ +  +  +L  Q+A C + LE S  L+  A   L+  D   F Q+AK I 
Sbjct: 297 KQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIA 356

Query: 122 DGVTMAPAFRLSLKAKVS--DNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179
           + V MA A    L   ++  D   +  +DF++E+++L+ L +L  P+ P I       + 
Sbjct: 357 ERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASH 416

Query: 180 NCVTLVWRMPDEDSKIDHYVLEYR----RTNF--------------------------EG 209
           + +T+ W + D++  I  Y L+Y     + NF                           G
Sbjct: 417 DTITVHW-ISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAG 475

Query: 210 PPR--LKEDQPWMVIEGIRQTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEPVTLETPA 267
            PR        WM++  I+Q  YT+ GL+   +Y+ F VKA N+A     SEP  L+T +
Sbjct: 476 APRGLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI-FIVKAINQA-GSRNSEPTRLKTNS 533

Query: 268 FMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKR 327
             F+LD   +H+ L++ +  ++              EKD          S  + + +P+R
Sbjct: 534 QPFKLDPKMTHKKLKISNDGLQM-------------EKD---------ESSLKKSHTPER 571

Query: 328 MPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKT 387
             SG G         Y   G+  ID G HYWEV     S  + +G+AY+S  + E +GK 
Sbjct: 572 F-SGTG--------CYGAAGNIFIDSGCHYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKN 621

Query: 388 AASWCLHVNNWLQVSFTAKHANKVKVLDAPVP-DCLGVHCDFHQGLLSFYNARTKQVLHT 446
           A+SW     N    +F  +H NK  ++D P     LGV  D+   +LSFY+      LHT
Sbjct: 622 ASSWVFSRCN---SNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHT 678

Query: 447 FKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAV 478
           F   F  P+ P FT+W  S  + +GL  P  +
Sbjct: 679 FDVTFILPVCPTFTIWNKSLMILSGLPAPDFI 710


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score =  117 bits (293), Expect = 2e-26
 Identities = 102/376 (27%), Positives = 161/376 (42%), Gaps = 36/376 (9%)

Query: 5   REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64
           ++ L K +  +    + +Q+ I  L++ + + E +  + +E++    + L ++LEE +  
Sbjct: 271 KDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRAS 330

Query: 65  MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124
           +L  I++ +  R   L  Q+    R+L     L+  A + L+  D   F QAAKQ+ + +
Sbjct: 331 LLQAIEECQQERLARLSAQIQE-HRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRI 389

Query: 125 TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADNCVTL 184
             A     + +   S +  H  +D  +E ++L  L FL VP APVID   +   D  + L
Sbjct: 390 ARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQ-IFL 448

Query: 185 VWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMNF 244
            WR+P       HY +E+RRT+    P       W   E +R T   L        Y+  
Sbjct: 449 CWRLPPHSPPAWHYTVEFRRTDVPAQP---GPTRWQRREEVRGTSALLENPDTGSVYV-L 504

Query: 245 RVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKARE 304
           RV+ CNKA  GE+SE V L TP       A   H  L         D+  G  ++  A  
Sbjct: 505 RVRGCNKAGYGEYSEDVHLHTP------PAPVLHFFL---------DSRWGASRERLAIS 549

Query: 305 KDGKGRTASPINSPARGTP---SPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVR 361
           KD +   + P      G P   +  R+ +G             VLGD  +  G  YW   
Sbjct: 550 KDQRAVRSVP------GLPLLLAADRLLTG------CHLSVDVVLGDVAVTQGRSYWACA 597

Query: 362 YEPDSKAFGVGVAYRS 377
            +P S    VGV   S
Sbjct: 598 VDPASYLVKVGVGLES 613


>gi|13994289 fibronectin type III and SPRY domain containing 1-like
           isoform 2 [Homo sapiens]
          Length = 145

 Score =  112 bits (281), Expect = 6e-25
 Identities = 56/118 (47%), Positives = 86/118 (72%)

Query: 1   MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE 60
           M+ Q+EAL++II TLA KN+EIQ+FI +L   L  V+ NS+ +  +L+ EF SL+S+L+E
Sbjct: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60

Query: 61  LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAK 118
           +KE M+  IKQ++A ++ ELQ+Q++ C  ALE+SEELLE A ++L   + E+F +  K
Sbjct: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKVHK 118


>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
          Length = 728

 Score =  101 bits (252), Expect = 1e-21
 Identities = 120/487 (24%), Positives = 201/487 (41%), Gaps = 68/487 (13%)

Query: 5   REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64
           +E L K I  L  K  +++S I  L  ++   E N  + +E+    F+ LF +LEE K  
Sbjct: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316

Query: 65  MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124
           +L  I   +  R  + Q Q+      LE++  L+  A + L+  D   F Q AKQ+   +
Sbjct: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETDQSCFVQTAKQLHLRI 375

Query: 125 TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVP-SAPVIDLAESLVADNCVT 183
             A     S +     +    +V+ +++ ++L  L F       P I+  +S V +N + 
Sbjct: 376 QKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNAL- 434

Query: 184 LVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMN 243
           + W  P++D K D YVLEYR+ N +      ++  W  IE +  T   +  L+    Y  
Sbjct: 435 INWHHPEKD-KADSYVLEYRKINRD------DEMSWNEIE-VCGTSKIIQDLENSSTYA- 485

Query: 244 FRVKACNKAVAGEFSEPVTLET---PAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDI 300
           FRV+A   ++    S  + L T   P F F  D    + N                 + +
Sbjct: 486 FRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNN-----------------EHL 528

Query: 301 KAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEV 360
               K  +  + +  N       + +R+  G      +T+  Y ++GDT I  G+H+W  
Sbjct: 529 LLNLKRDRVESRAGFNL----LLAAERIQVG-----YYTSLDY-IIGDTGITKGKHFWAF 578

Query: 361 RYEPDSKAFGVGVAYRS-------------LGRFEQ-LGKTAAS--WCLH-------VNN 397
           R EP S    VGVA                  R+EQ  G  + S   C         V  
Sbjct: 579 RVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTI 638

Query: 398 WLQVSFTAK---HANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQP 454
            +Q  F  K    +N+ +    P+P  +G+  D  +G + FY+    + L+  +   +  
Sbjct: 639 GMQKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHT 698

Query: 455 LLPAFTV 461
           L PAF +
Sbjct: 699 LYPAFAL 705


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 121/491 (24%), Positives = 208/491 (42%), Gaps = 78/491 (15%)

Query: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
           ++ +  L + +  ++ K +E + F+  LK +L  ++ N    +  L A+  +L   L   
Sbjct: 345 KQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQ 404

Query: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI- 120
           K  +L K+ ++R  +   + +Q+  CT  L  S  L+E   + ++  D   F Q +  + 
Sbjct: 405 KAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALI 464

Query: 121 -KDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLP----VPSAPVIDLAES 175
            +  V+     + +L+ KVS     L +D     Q +  L F+     VP  P++ L + 
Sbjct: 465 KRVQVSQEQWVKGALEPKVSAEFD-LTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKC 523

Query: 176 LVADNCVTLVWRMPD-EDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTG 234
              +N VTL WRMP    S +D Y+LE    +     + +E     V  G ++T  T+ G
Sbjct: 524 CTRNNSVTLAWRMPPFTHSPVDGYILE---LDDGAGGQFRE-----VYVG-KETLCTIDG 574

Query: 235 LKFDMKYMNFRVKACNKAVAGEFSEPVTLET-PAFMFRLDASTSHQNLRVDDLSVEWDAM 293
           L F+  Y N RVKA N +  G +S+ V L+T     F  D ++ H+++ + +        
Sbjct: 575 LHFNSTY-NARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSN-------- 625

Query: 294 GGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDG 353
                       D +  T S                         + +   VLG      
Sbjct: 626 ------------DNQTATCS-------------------------SYDDRVVLGTAAFSK 648

Query: 354 GEHYWEV---RYE--PDSKAFGVGVAYRSLGRFEQLGKTAASWCLHV-NNWLQVSFTAKH 407
           G HYWE+   RY+  PD      GVA  S+ +   LGK   +W ++V NN         H
Sbjct: 649 GVHYWELHVDRYDNHPDP---AFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSH 705

Query: 408 ANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQ 467
            N+ +         +GV  D ++  L+F+    +Q    F +      +PA ++   + Q
Sbjct: 706 TNRTEG-GVCKGATVGVLLDLNKHTLTFFINGQQQGPTAF-SHVDGVFMPALSL-NRNVQ 762

Query: 468 VT--TGLQVPS 476
           VT  TGL+VP+
Sbjct: 763 VTLHTGLEVPT 773


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 97/412 (23%), Positives = 168/412 (40%), Gaps = 82/412 (19%)

Query: 5   REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64
           +  L + +  L+ + +E + F+  L+ M+  ++ NS + +  L A+  +L   L   K  
Sbjct: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333

Query: 65  MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124
           +L ++ ++   +   +++Q++ CT  L  +  L+E   + ++  D   F Q +  +   V
Sbjct: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393

Query: 125 ----------TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAE 174
                     T+ P  R++    +S + S L+    Q    +Q     PVP+ P++ L E
Sbjct: 394 HLTEDQWGKGTLTP--RMTTDFDLSLDNSPLLQSIHQ-LDFVQVKASSPVPATPILQLEE 450

Query: 175 SLVADNCVTLVWRMPDEDS-KIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLT 233
               +N  TL W+ P   +   D Y+LE    N          Q   V  G ++T  T+ 
Sbjct: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGN--------GGQFREVYVG-KETMCTVD 501

Query: 234 GLKFDMKYMNFRVKACNKAVAGEFSEPVTLET-PAFMFRLDASTSHQN--LRVDDLSVEW 290
           GL F+  Y N RVKA NK     +S+ + L+T     F  D  ++H +  L  D+L+V  
Sbjct: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTC 560

Query: 291 DAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTL 350
            +   +V                                               VLG T 
Sbjct: 561 SSYDDRV-----------------------------------------------VLGKTG 573

Query: 351 IDGGEHYWEV---RYE--PDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNN 397
              G HYWE+   RY+  PD      GVA   + +   LGK   +W ++V+N
Sbjct: 574 FSKGIHYWELTVDRYDNHPDP---AFGVARMDVMKDVMLGKDDKAWAMYVDN 622


>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
           sapiens]
          Length = 749

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 65/266 (24%), Positives = 123/266 (46%), Gaps = 20/266 (7%)

Query: 1   MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE 60
           +E  ++ + K +  L  +  E+++F   L+++ + VE N  K +++ E+ +  +   L +
Sbjct: 209 LESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQ 268

Query: 61  LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI 120
             E  +  + + +  +   L  QL +C   L++ +EL+ET  +     +  DF      I
Sbjct: 269 KYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELMETIEEMCHE-EKVDF------I 321

Query: 121 KDGVTMAPAFRLSLKAKVSDNMS------HLMVDFAQERQMLQALKFLPVPSAPVID-LA 173
           KD V MA      LK K    +S         +DF+   Q++ ++  +P PSAPVI+   
Sbjct: 322 KDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQV 381

Query: 174 ESLVADNCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLT 233
            +    + V + W +  +D+ ++ Y L YR      P     DQ    +  +++T  ++T
Sbjct: 382 PNSATGSSVRVCWSLYSDDT-VESYQLSYRPVQDSSP---GTDQAEFTVT-VKETYCSVT 436

Query: 234 GLKFDMKYMNFRVKACNKAVAGEFSE 259
            L  + +Y  F V A N+A     SE
Sbjct: 437 NLVPNTQY-EFWVTAHNRAGPSPSSE 461



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 78/321 (24%), Positives = 128/321 (39%), Gaps = 42/321 (13%)

Query: 161 FLPVPSAPVIDLAESLVADNCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWM 220
           ++  PS P+I   E    +  V + W   + +  +D Y +E  +        + E     
Sbjct: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNP-VDSYTVELTQAESPEASGVTES---- 519

Query: 221 VIEGIRQTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQN 280
            + GI   E ++  L+    Y+ + V+A N       SEP T+ T    FRL+  T H  
Sbjct: 520 -VVGIPTCE-SVVQLQPGRSYIIY-VRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576

Query: 281 LRVDDLSVEWDAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTA 340
           L + +                    DG     S   +PAR     +  PS     D    
Sbjct: 577 LTISE--------------------DGLTAVRSERRTPAR-----ELSPS-----DTHFT 606

Query: 341 ESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCL-HVNNWL 399
               V+G+ +   G HYWEV  + +   + VGVA+  + + E LG    SWC+ H     
Sbjct: 607 RCVAVMGNLIPVRGHHYWEVEVD-EHLDYRVGVAFADVRKQEDLGANCLSWCMRHTFASS 665

Query: 400 QVSFTAKHANKVKVLDAPVPDC-LGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPA 458
           +  +   H      +   VP   +G+  D+    LSF+N    Q L+TF  +  + + P 
Sbjct: 666 RHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPC 725

Query: 459 FTV-WCGSFQVTTGLQVPSAV 478
           F++   G  +V  G+ +P  V
Sbjct: 726 FSLEKPGCLKVHNGISMPKHV 746


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 103/530 (19%), Positives = 200/530 (37%), Gaps = 69/530 (13%)

Query: 8    LRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEGMLM 67
            L + ++ L  K+  I++F+  ++     +E N +K ++ LE + + +   +    +    
Sbjct: 3549 LAEFLENLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQ 3608

Query: 68   KIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGVTMA 127
              ++ +  +   L  Q+    ++++++++ LET  +  + +D   F  + ++I + +  A
Sbjct: 3609 SFEEVKKKKMEFLHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERLLSA 3668

Query: 128  PAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAE-SLVADNCVTLVW 186
                 SL+   +        D +  R   Q LK + VP  P ++  E +      + + W
Sbjct: 3669 MESTASLEKMPAAFSLFEHYDDSSARSD-QMLKQVAVPQPPRLEPQEPNSATSTTIAVYW 3727

Query: 187  RM----------------PDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEY 230
             M                P +D +++  V EYR T  E     ++ +P    + +     
Sbjct: 3728 SMNKEDVIDSFQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQ-VWVMAV 3786

Query: 231  TLTGLKFDMKYMNFRVKACNKAVAGEF--------------SEPVTLETPAFMFRLDAST 276
              TG     +   FR       +  E               + P   ET    +    S 
Sbjct: 3787 NFTGCSLPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTTPEATETYTLEYCRQHSP 3846

Query: 277  SHQNLRVDDLSVEWDAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRG--- 333
              + LR       +  + G    +  +  D        IN+      S   + S RG   
Sbjct: 3847 EGEGLR------SFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRF 3900

Query: 334  ----------------------GRDRFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGV 371
                                  G  R   E  +VLG+ L   G+HYWE     D  A+ +
Sbjct: 3901 LLLRETAHPALHISSSGTVISFGERRRLTEIPSVLGEELPSCGQHYWETTVT-DCPAYRL 3959

Query: 372  GVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKH-ANKVKVLDAPVPDCLGVHCDFHQ 430
            G+   S  +   LG+   SW +H +   + +F      + V V + P    +G+  D++ 
Sbjct: 3960 GICSSSAVQAGALGQGETSWYMHCSEPQRYTFFYSGIVSDVHVTERPAR--VGILLDYNN 4017

Query: 431  GLLSFYNARTKQVLHTFKTRFTQPLLPAFTV-WCGSFQVTTGLQVPSAVR 479
              L F NA ++Q+L   + RF + + PAF +   G   +  G++ P +VR
Sbjct: 4018 QRLIFINAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPPDSVR 4067


>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
          Length = 550

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 67/272 (24%), Positives = 123/272 (45%), Gaps = 24/272 (8%)

Query: 5   REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64
           +  L + +  L+ + +E + F+  L+ M+  ++ NS + +  L A+  +L   L   K  
Sbjct: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333

Query: 65  MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124
           +L ++ ++   +   +++Q++ CT  L  +  L+E   + ++  D   F Q +  +   V
Sbjct: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393

Query: 125 ----------TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAE 174
                     T+ P  R++    +S + S L+    Q    +Q     PVP+ P++ L E
Sbjct: 394 HLTEDQWGKGTLTP--RMTTDFDLSLDNSPLLQSIHQ-LDFVQVKASSPVPATPILQLEE 450

Query: 175 SLVADNCVTLVWRMPDEDS-KIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLT 233
               +N  TL W+ P   +   D Y+LE    N          Q   V  G ++T  T+ 
Sbjct: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGN--------GGQFREVYVG-KETMCTVD 501

Query: 234 GLKFDMKYMNFRVKACNKAVAGEFSEPVTLET 265
           GL F+  Y N RVKA NK     +S+ + L+T
Sbjct: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQT 532


>gi|46409324 SPRY domain containing 4 [Homo sapiens]
          Length = 207

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 44/135 (32%), Positives = 66/135 (48%), Gaps = 5/135 (3%)

Query: 345 VLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFT 404
           VL DT +  G HYWEV  +  S+ F +GVA   + R   +G    SW   V  + Q  + 
Sbjct: 77  VLADTAVTSGRHYWEVTVKR-SQQFRIGVADVDMSRDSCIGVDDRSW---VFTYAQRKWY 132

Query: 405 AKHAN-KVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWC 463
              AN K  V     P+ +G+  ++    LS  +     V+HT +T F  P++PAF +W 
Sbjct: 133 TMLANEKAPVEGIGQPEKVGLLLEYEAQKLSLVDVSQVSVVHTLQTDFRGPVVPAFALWD 192

Query: 464 GSFQVTTGLQVPSAV 478
           G     +GL+VP  +
Sbjct: 193 GELLTHSGLEVPEGL 207


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 8/132 (6%)

Query: 343 YTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGR-----FEQLGKTAASWCLHVNN 397
           + VL       G HYWEV  +     + VG AY SL R       +LG    SWCL   +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 398 WLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQV-LHTFKTRFTQPLL 456
               +F     ++++  D    D LGV  D+  G+L+FY+       LHTF+  F +PL 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426

Query: 457 PAFTVWCGSFQV 468
           PA  +W G+  +
Sbjct: 427 PALRLWEGAISI 438


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 8/132 (6%)

Query: 343 YTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGR-----FEQLGKTAASWCLHVNN 397
           + VL       G HYWEV  +     + VG AY SL R       +LG    SWCL   +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 398 WLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQV-LHTFKTRFTQPLL 456
               +F     ++++  D    D LGV  D+  G+L+FY+       LHTF+  F +PL 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426

Query: 457 PAFTVWCGSFQV 468
           PA  +W G+  +
Sbjct: 427 PALRLWEGAISI 438


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 8/132 (6%)

Query: 343 YTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGR-----FEQLGKTAASWCLHVNN 397
           + VL       G HYWEV  +     + VG AY SL R       +LG    SWCL   +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 398 WLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQV-LHTFKTRFTQPLL 456
               +F     ++++  D    D LGV  D+  G+L+FY+       LHTF+  F +PL 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426

Query: 457 PAFTVWCGSFQV 468
           PA  +W G+  +
Sbjct: 427 PALRLWEGAISI 438


>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
          Length = 353

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 1/159 (0%)

Query: 4   QREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKE 63
           Q+  L   I  L   N+ +Q+ I  L+      + NS +V+E+L  +F +L+++L+E K 
Sbjct: 166 QKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKS 225

Query: 64  GMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQ-IKD 122
            +L +I Q++  +   ++  +      L+ S +L+ETA Q+L       F   AKQ IK 
Sbjct: 226 ELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKS 285

Query: 123 GVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKF 161
            V  +   +L    +  +NM    +D       L+A+ F
Sbjct: 286 IVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAIDF 324


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 44/130 (33%), Positives = 65/130 (50%), Gaps = 9/130 (6%)

Query: 337 RFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRF---EQLGKTAASWCL 393
           RFT  S  VLG      G HYWEV  + ++   GVG+ Y S+ R     +LG+ +ASWC+
Sbjct: 494 RFTYCSQ-VLGLHCYKKGIHYWEVELQKNNFC-GVGICYGSMNRQGPESRLGRNSASWCV 551

Query: 394 HVNNWLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTK-QVLHTFKTRFT 452
               W     +A H N  K L +     +GV  +   G + F+    K  +++ F+  FT
Sbjct: 552 E---WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFT 608

Query: 453 QPLLPAFTVW 462
           + L PAF V+
Sbjct: 609 EALYPAFWVF 618


>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
          Length = 517

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 51/159 (32%), Positives = 66/159 (41%), Gaps = 16/159 (10%)

Query: 327 RMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGR------ 380
           R   G GG   F  E + V        G HYWEVR    S    +GV+Y  L R      
Sbjct: 357 RQSRGPGGPGSF--ELWQVQCAQSFQAGHHYWEVRASDHSVT--LGVSYPQLPRCRLGPH 412

Query: 381 FEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNART 440
            + +G+   SW L V    + S  A H  + + L       LG+  D   G L+FY+   
Sbjct: 413 TDNIGRGPCSWGLCVQ---EDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEP 469

Query: 441 K-QVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAV 478
           + Q L+TF   F QPL P F  W    +  T    P AV
Sbjct: 470 QTQPLYTFHALFNQPLTPVF--WLLEGRTLTLCHQPGAV 506


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 17/124 (13%)

Query: 344 TVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSF 403
           ++LG      G HYWEV Y  D   + +GV   S+ R  ++  + A+      +WL    
Sbjct: 281 SILGSEYFTTGCHYWEV-YVGDKTKWILGVCSESVSRKGKVTASPAN-----GHWL---L 331

Query: 404 TAKHANKVKVLDAPV--------PDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPL 455
                N+ + L +P         P C+G+  D+  G++SFYN   K  + TF   F+ PL
Sbjct: 332 RQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPL 391

Query: 456 LPAF 459
            P F
Sbjct: 392 RPFF 395


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 17/124 (13%)

Query: 344 TVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSF 403
           ++LG      G HYWEV Y  D   + +GV   S+ R  ++  + A+      +WL    
Sbjct: 281 SILGSEYFTTGCHYWEV-YVGDKTKWILGVCSESVSRKGKVTASPAN-----GHWL---L 331

Query: 404 TAKHANKVKVLDAPV--------PDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPL 455
                N+ + L +P         P C+G+  D+  G++SFYN   K  + TF   F+ PL
Sbjct: 332 RQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPL 391

Query: 456 LPAF 459
            P F
Sbjct: 392 RPFF 395


>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
          Length = 358

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 39/173 (22%), Positives = 85/173 (49%), Gaps = 1/173 (0%)

Query: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
           + Q+  L   I  L   N+ +Q+ I  ++++   +E NS + ++ L   F+SL ++LEE 
Sbjct: 168 KRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEER 227

Query: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
           K  +L  + +++  +   ++  +      LE+S +L+E+A Q+++      + Q AK++ 
Sbjct: 228 KGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELI 287

Query: 122 DGVTMAPAFRLSLKAKVS-DNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLA 173
           + V       L+ + +   ++M    V      +ML+ + F P  S    ++A
Sbjct: 288 NKVGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVA 340


>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
          Length = 432

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/130 (30%), Positives = 66/130 (50%), Gaps = 7/130 (5%)

Query: 337 RFTAESYT---VLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCL 393
           R++ E ++   VL    +  G+HYWEV    +   + VGVA   + R + LG+T  S C+
Sbjct: 291 RWSCERFSTSQVLCSQALSSGKHYWEVDTR-NCSHWAVGVASWEMSRDQVLGRTMDSCCV 349

Query: 394 HVNNWLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNA-RTKQVLHTFKTRFT 452
                 Q+S  A H  K  VL +  P  +G+  +  +G L+FY+    +++L+      +
Sbjct: 350 EWKGTSQLS--AWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISAS 407

Query: 453 QPLLPAFTVW 462
            PL PAF ++
Sbjct: 408 SPLYPAFWLY 417


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 1/115 (0%)

Query: 345 VLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFT 404
           VLG      G HYWEV      K   +GV    L R  Q   +       +  +++  + 
Sbjct: 339 VLGSQRFSSGRHYWEVEVGNKPKWI-LGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYV 397

Query: 405 AKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAF 459
           A      ++L    P  +G+  D+  G LSFYN   + +L+TF   FT+ + P F
Sbjct: 398 ASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYF 452


>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
          Length = 400

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 37/163 (22%), Positives = 81/163 (49%), Gaps = 1/163 (0%)

Query: 12  IKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEGMLMKIKQ 71
           I  L   N+ +Q+ I  ++++   +E NS + ++ L   F+SL ++LEE K  +L  + +
Sbjct: 220 IAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAR 279

Query: 72  DRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGVTMAPAFR 131
           ++  +   ++  +      LE+S +L+E+A Q+++      + Q AK++ + V       
Sbjct: 280 EQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVE 339

Query: 132 LSLKAKVS-DNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLA 173
           L+ + +   ++M    V      +ML+ + F P  S    ++A
Sbjct: 340 LAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVA 382


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 6/126 (4%)

Query: 337 RFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFE--QLGKTAASWCLH 394
           RF  E  +VLG      G HYWEV    +   + +G+A+ +  R    Q+  +   +C+ 
Sbjct: 333 RFDVE-VSVLGSEAFSSGVHYWEV-VVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIV 390

Query: 395 VNNWLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQP 454
           +++  Q S   +   ++ V D    D +GV  D+ QGLL FYNA     L+TF+ +F   
Sbjct: 391 MHDGNQYSACTEPWTRLNVRDKL--DKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGK 448

Query: 455 LLPAFT 460
           L   F+
Sbjct: 449 LCSYFS 454



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 30  KQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEGMLMKIKQDRASRTYELQNQLAACTR 89
           K ML  +EA++A+   D+E + Q     L +++EG   +I Q+R + T +    LA    
Sbjct: 194 KAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEG--AQILQERLAET-DRHTFLAGVAS 250

Query: 90  ALESSEELLETANQTLQAMDSEDFP 114
             E  +  +   N T      EDFP
Sbjct: 251 LSERLKGKIHETNLTY-----EDFP 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.131    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,923,559
Number of Sequences: 37866
Number of extensions: 818349
Number of successful extensions: 3737
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 244
Number of HSP's that attempted gapping in prelim test: 3218
Number of HSP's gapped (non-prelim): 681
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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