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Search of human proteins with 13236559
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13236559 hypothetical protein LOC79169 [Homo sapiens]
(263 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13236559 hypothetical protein LOC79169 [Homo sapiens] 543 e-155
gi|50083281 KIAA1853 protein [Homo sapiens] 50 2e-06
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 50 2e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 3e-06
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 49 3e-06
gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] 49 3e-06
gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens] 49 3e-06
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 49 4e-06
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 49 4e-06
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 49 6e-06
gi|151301228 formin binding protein 3 [Homo sapiens] 48 1e-05
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 47 2e-05
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 46 3e-05
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 46 4e-05
gi|42718020 retinitis pigmentosa 9 [Homo sapiens] 45 6e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 45 6e-05
gi|52426743 cisplatin resistance-associated overexpressed protei... 45 6e-05
gi|19923485 cisplatin resistance-associated overexpressed protei... 45 6e-05
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 44 1e-04
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 44 1e-04
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 44 1e-04
gi|50962882 G patch domain containing 8 [Homo sapiens] 44 1e-04
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 44 1e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 44 1e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 44 1e-04
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 44 2e-04
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 44 2e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 44 2e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 44 2e-04
>gi|13236559 hypothetical protein LOC79169 [Homo sapiens]
Length = 263
Score = 543 bits (1400), Expect = e-155
Identities = 263/263 (100%), Positives = 263/263 (100%)
Query: 1 MFGSSRGGVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKGRAPCAG 60
MFGSSRGGVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKGRAPCAG
Sbjct: 1 MFGSSRGGVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKGRAPCAG 60
Query: 61 PSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLG 120
PSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLG
Sbjct: 61 PSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLG 120
Query: 121 LGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCE 180
LGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCE
Sbjct: 121 LGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCE 180
Query: 181 SHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKR 240
SHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKR
Sbjct: 181 SHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKR 240
Query: 241 RKRGHSGDRRSPSRRWHDRGSEA 263
RKRGHSGDRRSPSRRWHDRGSEA
Sbjct: 241 RKRGHSGDRRSPSRRWHDRGSEA 263
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 50.4 bits (119), Expect = 2e-06
Identities = 45/173 (26%), Positives = 65/173 (37%), Gaps = 26/173 (15%)
Query: 110 PEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKP 169
P + G LG A+ +G + R DK +LG + H T S+R K
Sbjct: 54 PAQDGPSEKLGQHLATEPLGTNSWER-DKTCRELGAT--RGHSASHDKDLTPPPSSRGKK 110
Query: 170 RAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERP----- 224
+ + T KKKK+K K+ K++ ++ ++SSP S R
Sbjct: 111 KKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHK 170
Query: 225 -----------RHHHH-------DSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
RH HH S+S C+ R RG S + SRR H R
Sbjct: 171 KQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSR 223
Score = 31.2 bits (69), Expect = 0.96
Identities = 21/97 (21%), Positives = 38/97 (39%), Gaps = 2/97 (2%)
Query: 155 SGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEA 214
S + + + R PR +S E S+ K K + + + R P+ +
Sbjct: 400 SSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGK-RSPPSRSSRSRRSPSYS 458
Query: 215 TSSPTSPERPRHHHHDSDSNS-PCCKRRKRGHSGDRR 250
SP+ P++ DS +RR+R +S R+
Sbjct: 459 RYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRK 495
Score = 30.0 bits (66), Expect = 2.1
Identities = 15/55 (27%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 168 KPRAEDQTESSCES-HRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSP 221
+ ++ + SSCES HR E+ +K +R+H + K + A+++ P+ P
Sbjct: 191 RSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 50.1 bits (118), Expect = 2e-06
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 159 GTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSP 218
G R+K + E + K +KE+++K++RK KKEKKK++++ R E
Sbjct: 59 GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK 118
Query: 219 TSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRG 260
ER R + + ++RK+ RR +R +RG
Sbjct: 119 ERKERERENKQRRE------RKRKKRRKKKRRKERKREKERG 154
Score = 45.4 bits (106), Expect = 5e-05
Identities = 23/97 (23%), Positives = 43/97 (44%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPR 225
++K R E + E+ RK KK +KKK++++ K+EK++ +E +R
Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175
Query: 226 HHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSE 262
+ + RK+ +RR R DR ++
Sbjct: 176 RKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
Score = 42.7 bits (99), Expect = 3e-04
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 13/105 (12%)
Query: 158 PGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSS 217
P T S R+K R E + K K+E++K++KR+ K++KKK K+ R E
Sbjct: 28 PCTQRESERKKERRERE---------KRKREREKERKRERGKKEKKKRKKRERGKERERK 78
Query: 218 PTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSE 262
E+ R + + KR+K +R+ RR + E
Sbjct: 79 RKEREKQRKERREKERR----KRKKEKKKRERKQRGRRERKKKKE 119
Score = 42.4 bits (98), Expect = 4e-04
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKK-------RKHKKEKKKKDKEHRRPAEATSSP 218
+RK R + + E + RK KKEKKK+++ RK KKE+K++++E+++ E
Sbjct: 78 KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
Query: 219 TSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRR 255
++ R ++RK+ +R R
Sbjct: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
Score = 40.8 bits (94), Expect = 0.001
Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 6/123 (4%)
Query: 135 REDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKK 194
R +KE K R + G R++ E++ + ++ KK+++K++K
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 195 R------KHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGD 248
R + +K KK+K +E + E ER R + +R+K+ D
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Query: 249 RRS 251
R++
Sbjct: 209 RKT 211
Score = 39.3 bits (90), Expect = 0.004
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 166 RRKPRAEDQTESSCESHRKSKKE--KKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPER 223
RR+ + + + + RK +KE K+++K++K KKE+++K +E R R
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
Query: 224 PRHHHHDSDSNSPCCKRRKRGHSGDRRSPSR 254
R + K RK+ DR++ S+
Sbjct: 190 ERKKERKKERRKK--KERKKDRKTDRQTDSQ 218
Score = 37.4 bits (85), Expect = 0.013
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 5/102 (4%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKK----KKRKHKKEKKKKDKEHRRPAEATSSPTSP 221
R+K + + + + RK KKE+K++ K+R+ +K KK++ K+ R+ +
Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR 156
Query: 222 ERPRHHHHDSDSNSPCCKRRK-RGHSGDRRSPSRRWHDRGSE 262
ER R + + RK R +R+ R +R E
Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKE 198
Score = 36.6 bits (83), Expect = 0.023
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPER 223
R K R ++ E E RK ++E+KK++K K +++KK++ K+ + + S P R
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERK-KERRKKKERKKDRKTDRQTDSQVFRPLR 224
Score = 35.8 bits (81), Expect = 0.039
Identities = 19/90 (21%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 167 RKPRAEDQTESSCESHRKSKKEKK-KKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPR 225
R+ R + + E K ++E+K KK+++K +++++K++KE + ER +
Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
Query: 226 HHHHDSDSNSPCCKRRKRGHSGDRRSPSRR 255
+ +R++R R RR
Sbjct: 171 KRERNRKERKKERERKERRERKKERKKERR 200
Score = 33.5 bits (75), Expect = 0.19
Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 12/99 (12%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKK--KKKKRKHKKEKKKKDKEHRRPAEATSSPTSPER 223
RRK + E + + R+ +K+KK K+++R++K+ +++K K+ R+ ER
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
Query: 224 PRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSE 262
+ KR+KR + R +R E
Sbjct: 154 GKRER----------KRKKRKKEEREKKRERNRKERKKE 182
Score = 29.6 bits (65), Expect = 2.8
Identities = 18/94 (19%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 162 AASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSP 221
++ A K E Q S + + + ++KK + ++EK+K+++E R E
Sbjct: 6 SSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKK 65
Query: 222 ERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRR 255
+ R + + ++ + +RR RR
Sbjct: 66 RKKRERGKERERK----RKEREKQRKERREKERR 95
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 50.1 bits (118), Expect = 2e-06
Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Query: 151 HRVESGGPGTSAA-SARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHR 209
HR PG+ A+ SARR+ R+ ++ S+ +S ++ +R +EK+++ +
Sbjct: 555 HRSRDRKPGSHASSSARRRSRSRSRSRST-RRRSRSTDRRRGGSRRSRSREKRRRRRRSA 613
Query: 210 RPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRS 251
P ATSS +S R RH D K+++ G++RS
Sbjct: 614 SPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRS 655
Score = 36.2 bits (82), Expect = 0.030
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 159 GTSAASARRKPRAEDQTESSCE--SHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAE-AT 215
G S+ RR+ A + SS E S RK+ + + R +++ + K+ R P E A
Sbjct: 744 GKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAP 803
Query: 216 SSPTSPERPRHHHHDSDSNSPCCKRRK 242
SS P+ P S S+S C RK
Sbjct: 804 SSGPPPKPPVSSGSGSSSSSSSCSSRK 830
Score = 35.0 bits (79), Expect = 0.067
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query: 152 RVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRP 211
R S P TS++S+ R+ R + HR KKKKK+ + + EK+ D + P
Sbjct: 611 RSASPPPATSSSSSSRRERHRGK-------HRDGGGSKKKKKRSRSRGEKRSGDGSEKAP 663
Query: 212 AEA 214
A A
Sbjct: 664 APA 666
Score = 28.9 bits (63), Expect = 4.8
Identities = 19/75 (25%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 189 KKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSP-ERPRHHHHDSDSNSPCCKRRKRGHSG 247
KK +++RK E K+ A +P SP + +H D S +R
Sbjct: 517 KKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRS 576
Query: 248 DRRSPSRRWHDRGSE 262
RS S R R ++
Sbjct: 577 RSRSRSTRRRSRSTD 591
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 49.3 bits (116), Expect = 3e-06
Identities = 50/219 (22%), Positives = 84/219 (38%), Gaps = 29/219 (13%)
Query: 57 PCAGPSREEELAAVREAEREALLAALGYKN------VKKQPTGLSKEDFAEVCKREGGDP 110
PC P + E +RE ERE G K +++ K + + KRE G
Sbjct: 28 PCTQPGWQSE---IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK 84
Query: 111 EEKGV------DRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAAS 164
E+KG +R G R+ KE + G R G
Sbjct: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERG-------RTSKEGKERERKE 137
Query: 165 AR----RKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTS 220
R RK R + E E RK +K++++K+ + ++E+K+K+++ R+ E
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
Query: 221 PERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
ER R + + RK+ DR++ W ++
Sbjct: 198 KERERKERRERKKERKKKEERKKERQKDRQT---NWREK 233
Score = 30.0 bits (66), Expect = 2.1
Identities = 30/134 (22%), Positives = 52/134 (38%), Gaps = 14/134 (10%)
Query: 85 KNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLG 144
K KK+ SKE K E E K +R R R+ +E ++G
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERK----KEEREKERERKERKKRERKQVG 172
Query: 145 LSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHK------ 198
R E RK R +++ +K +K+K+++KK + K
Sbjct: 173 EK--EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNW 230
Query: 199 --KEKKKKDKEHRR 210
KE+ K++++ R+
Sbjct: 231 REKERGKRERKERK 244
Score = 28.1 bits (61), Expect = 8.2
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 16/57 (28%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKH----------------KKEKKKKDK 206
R + R E + E + R+ KKE+KKK++RK K+E+K++ K
Sbjct: 189 RERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 49.3 bits (116), Expect = 3e-06
Identities = 22/42 (52%), Positives = 31/42 (73%)
Query: 169 PRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
P+ E++ E E +K KK+KKKKKK+K KK+KKKK K+ +R
Sbjct: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKR 141
Score = 46.2 bits (108), Expect = 3e-05
Identities = 20/45 (44%), Positives = 32/45 (71%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
+R+ + E + E + +K KK+KKKKKK+K KK+KKKK ++ +R
Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKR 145
Score = 43.5 bits (101), Expect = 2e-04
Identities = 19/45 (42%), Positives = 31/45 (68%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
R + + +++ + + +K KK+KKKKKK+K KK+KKKK K R+
Sbjct: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146
Score = 42.7 bits (99), Expect = 3e-04
Identities = 18/44 (40%), Positives = 31/44 (70%)
Query: 167 RKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
+K + +++ + + +K KK+KKKKKK+K KK+KK+K K R+
Sbjct: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148
Score = 42.0 bits (97), Expect = 5e-04
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Query: 180 ESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCK 239
E K K++KKKKKK+K KK+KKKK K+ ++ + +R R K
Sbjct: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKK-----K 158
Query: 240 RRKRGHSG 247
++K G+ G
Sbjct: 159 KKKTGNEG 166
Score = 42.0 bits (97), Expect = 5e-04
Identities = 17/45 (37%), Positives = 32/45 (71%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
++K + + + + + +K KK+KKKKKKRK K+++K+K K+ R+
Sbjct: 112 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/52 (32%), Positives = 32/52 (61%)
Query: 159 GTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
G +++ E + + + +K KK+KKKKKK+K KK+K+K+ ++ +R
Sbjct: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR 149
Score = 40.4 bits (93), Expect = 0.002
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 156 GGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
G P + K + + + + + +K KK+KKKKKK+K K+++K+K K R+
Sbjct: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152
Score = 39.7 bits (91), Expect = 0.003
Identities = 15/45 (33%), Positives = 31/45 (68%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
++K + + + + + +K KK+KKKK+KRK K+++K+K K ++
Sbjct: 114 KKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158
Score = 39.7 bits (91), Expect = 0.003
Identities = 15/45 (33%), Positives = 32/45 (71%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
++K + + + + + +K KK+KK+K+KRK K+++KKK K+ ++
Sbjct: 116 KKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160
Score = 39.3 bits (90), Expect = 0.004
Identities = 16/61 (26%), Positives = 35/61 (57%)
Query: 167 RKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRH 226
++ + + + + + +K KK+KKKKKK+K +K K+K+ ++ ++ + T E +
Sbjct: 110 KEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKI 169
Query: 227 H 227
H
Sbjct: 170 H 170
Score = 38.9 bits (89), Expect = 0.005
Identities = 14/52 (26%), Positives = 34/52 (65%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSS 217
++K + + + + + +K KK+KKKKK+++ +K K+K+ K+ ++ + T +
Sbjct: 113 KKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164
Score = 38.5 bits (88), Expect = 0.006
Identities = 15/45 (33%), Positives = 30/45 (66%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRR 210
+ K + + + + + +K KK+KKKKKK+K K+++K+K K ++
Sbjct: 110 KEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154
Score = 37.7 bits (86), Expect = 0.010
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 13/80 (16%)
Query: 183 RKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRK 242
R+ KKEK+K+KK+K KK+KKKK K+ ++ + +R R ++RK
Sbjct: 102 REEKKEKEKEKKKK-KKKKKKKKKKKKKKKKKKKKKKKKKRKRK------------RKRK 148
Query: 243 RGHSGDRRSPSRRWHDRGSE 262
R R+ ++ + G++
Sbjct: 149 RKRKKKRKKKKKKTGNEGAK 168
Score = 35.8 bits (81), Expect = 0.039
Identities = 14/42 (33%), Positives = 28/42 (66%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKE 207
++K + + + + + RK K+++K+K+K+K KK+KKK E
Sbjct: 124 KKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165
Score = 30.4 bits (67), Expect = 1.6
Identities = 13/43 (30%), Positives = 26/43 (60%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEH 208
++K + + + + + RK K+++KKK+K+K KK + K H
Sbjct: 128 KKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAKIH 170
>gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]
Length = 758
Score = 49.3 bits (116), Expect = 3e-06
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 161 SAASARRKPRAEDQTESSCESH---RKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSS 217
SA R+ +++ + S SH + ++E + +++R+ + +++ D E R +
Sbjct: 11 SAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMR 70
Query: 218 PTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGS 261
SP RP+ H D S S + + RG RR +R W S
Sbjct: 71 SRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSS 114
>gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens]
Length = 758
Score = 49.3 bits (116), Expect = 3e-06
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 161 SAASARRKPRAEDQTESSCESH---RKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSS 217
SA R+ +++ + S SH + ++E + +++R+ + +++ D E R +
Sbjct: 11 SAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMR 70
Query: 218 PTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGS 261
SP RP+ H D S S + + RG RR +R W S
Sbjct: 71 SRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSS 114
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 48.9 bits (115), Expect = 4e-06
Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 6/126 (4%)
Query: 128 VGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKK 187
V + S + ++G+S H S P S + + + R+ + SS ES KK
Sbjct: 1636 VEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKK 1695
Query: 188 EKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSG 247
+KKK+KK+ K +K KK K+H + E+ + H H + + K
Sbjct: 1696 KKKKEKKKHKKHKKHKKHKKH------AGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
Query: 248 DRRSPS 253
D++ S
Sbjct: 1750 DQKVKS 1755
Score = 33.9 bits (76), Expect = 0.15
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 14/81 (17%)
Query: 149 THHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKK--------------EKKKKKK 194
T S S S ++K + E + + H+K KK + KKKK
Sbjct: 1677 TRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKS 1736
Query: 195 RKHKKEKKKKDKEHRRPAEAT 215
+K+K ++K+K+K+ ++ T
Sbjct: 1737 KKNKDKEKEKEKDDQKVKSVT 1757
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 48.9 bits (115), Expect = 4e-06
Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 6/126 (4%)
Query: 128 VGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKK 187
V + S + ++G+S H S P S + + + R+ + SS ES KK
Sbjct: 1670 VEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKK 1729
Query: 188 EKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSG 247
+KKK+KK+ K +K KK K+H + E+ + H H + + K
Sbjct: 1730 KKKKEKKKHKKHKKHKKHKKH------AGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1783
Query: 248 DRRSPS 253
D++ S
Sbjct: 1784 DQKVKS 1789
Score = 33.9 bits (76), Expect = 0.15
Identities = 36/121 (29%), Positives = 44/121 (36%), Gaps = 24/121 (19%)
Query: 158 PGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSS 217
P T A R+ +Q E +KSK ++ K E KK KE RR + S
Sbjct: 629 PTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKS 688
Query: 218 PTS-----------------PERPRHH-------HHDSDSNSPCCKRRKRGHSGDRRSPS 253
P S R R + H S S SP RR RG S + RS S
Sbjct: 689 PYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRS 748
Query: 254 R 254
R
Sbjct: 749 R 749
Score = 33.9 bits (76), Expect = 0.15
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 14/81 (17%)
Query: 149 THHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKK--------------EKKKKKK 194
T S S S ++K + E + + H+K KK + KKKK
Sbjct: 1711 TRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKS 1770
Query: 195 RKHKKEKKKKDKEHRRPAEAT 215
+K+K ++K+K+K+ ++ T
Sbjct: 1771 KKNKDKEKEKEKDDQKVKSVT 1791
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 48.5 bits (114), Expect = 6e-06
Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 21/108 (19%)
Query: 152 RVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKK-----EKKKKDK 206
R+ES S++ R+K + S + HR+ + + ++KR+H+ ++K+K+K
Sbjct: 186 RLESECSCGSSSPLRKKKK-------SVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNK 238
Query: 207 EHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSR 254
E +RP SP R H H S+SP H D RSPSR
Sbjct: 239 EKKRP-----HTESPGRRSHRHSSGSSHSPSLS----SHYSDSRSPSR 277
Score = 35.4 bits (80), Expect = 0.051
Identities = 60/244 (24%), Positives = 89/244 (36%), Gaps = 62/244 (25%)
Query: 61 PSREEELAA-----VREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGV 115
P EEEL A V+ A RE L + +K+ L + E+ + +G EE +
Sbjct: 33 PRAEEELRAAEPGLVKRAHREIL------DHERKRRVELKCMELQEMMEEQGYSEEE--I 84
Query: 116 DRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQT 175
+ +G ++RED+ + T E PG A P +D
Sbjct: 85 RQKVGTFRQMLMEKEGVLTREDRPGGHIVAE--TPRLTEGAEPGLEYA-----PFDDDDG 137
Query: 176 ESSCE------------------SHRKSKKEKKKKKKR-KHKKEKKKKDKEHRRPAEATS 216
C+ S S KKKKKK+ H++ +KK+ R +E +
Sbjct: 138 PVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKR----RLESECSC 193
Query: 217 SPTSPER------PRHHHHDSD----------SNSPCCKRRKRGHSGDR---RSPSRRWH 257
+SP R +H SD S S CKR+++ R SP RR H
Sbjct: 194 GSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH 253
Query: 258 DRGS 261
S
Sbjct: 254 RHSS 257
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 23/126 (18%)
Query: 150 HHRVES----GGPGTSAASARRKPRAEDQTESSCE---------SHRKSKKEKKKKKKRK 196
HHR S G S +K R ++ S+ E S++KSKK KKK KKR+
Sbjct: 794 HHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRR 853
Query: 197 HKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRW 256
HK + + D E + + + +R R +S SP ++K G S W
Sbjct: 854 HKSDSPESDAEREKDKKEKDRESEKDRTR-QRSESKHKSP---KKKTG------KDSGNW 903
Query: 257 HDRGSE 262
GSE
Sbjct: 904 DTSGSE 909
Score = 38.1 bits (87), Expect = 0.008
Identities = 29/111 (26%), Positives = 37/111 (33%), Gaps = 27/111 (24%)
Query: 176 ESSCESHRKSKKEKKKKKKRKHKK----------------EKKKKDKEHRRPAEATSSPT 219
E C+ H K+ KK K+ H+K KKK+ + R A SS
Sbjct: 774 EHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSA 833
Query: 220 SPER-----------PRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
ER + H SDS +R K DR S R R
Sbjct: 834 ESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQR 884
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 47.0 bits (110), Expect = 2e-05
Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 27/143 (18%)
Query: 85 KNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLG 144
+ ++ Q T + + FAEV R+L G + + + +E+K+ K
Sbjct: 152 REIENQKTDAASKPFAEV--------------RILSCGEL---IPKSKVKKEEKKRHKSS 194
Query: 145 LSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKK--RKHKKEKK 202
S S + + S+ + D ++S + KSKK KKK +K RKHKKEKK
Sbjct: 195 SS--------SSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKK 246
Query: 203 KKDKEHRRPAEATSSPTSPERPR 225
K+ K + + + + +P+
Sbjct: 247 KRKKSKKSASSESEAENLEAQPQ 269
Score = 35.8 bits (81), Expect = 0.039
Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 11/109 (10%)
Query: 152 RVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRP 211
R+ S G + + K + D E R KEK K+ + K + K KE R
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSDSKGKDQE--RSRSKEKSKQLESKSNEHDHSKSKEKDRR 541
Query: 212 AEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDR-RSPSRRWHDR 259
A++ S + +H ++ + R+R S DR R R HDR
Sbjct: 542 AQSRSRECDITKGKHSYNS--------RTRERSRSRDRSRRVRSRTHDR 582
Score = 35.4 bits (80), Expect = 0.051
Identities = 20/93 (21%), Positives = 35/93 (37%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPR 225
RR +D+ ++ + KSK K K+K K K+ K ++ + + S E +
Sbjct: 439 RRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVK 498
Query: 226 HHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHD 258
SDS +R + + HD
Sbjct: 499 EKEKQSDSKGKDQERSRSKEKSKQLESKSNEHD 531
Score = 33.1 bits (74), Expect = 0.25
Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Query: 158 PGTSAASARRKPRAEDQTESSCESHRKSK-KEKKKKKKRKHKKEKKKKDKE-HRRPAEAT 215
PG S + RR+ R + ++ ES ++K K + ++ K H+KE + +K + + +
Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHN 672
Query: 216 SSPTSPER 223
SS S E+
Sbjct: 673 SSNNSREK 680
Score = 32.0 bits (71), Expect = 0.57
Identities = 25/104 (24%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Query: 160 TSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPT 219
T AAS KP AE + S E KSK +K++KK+ K + +++ SS
Sbjct: 159 TDAAS---KPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSD 215
Query: 220 SPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSEA 263
S + S ++ R H +++ + SE+
Sbjct: 216 SSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSES 259
Score = 31.6 bits (70), Expect = 0.74
Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 15/114 (13%)
Query: 161 SAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHK--KEKKK------KDKEHRRPA 212
S + ++ K +++ + S + + K+ + + K R H+ KEK+K KD+E R
Sbjct: 458 SKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 213 EATSSPTSPERPRHHHHDSD------SNSPCCKRRKRGHSGDRRSPSR-RWHDR 259
E + S H + S S C K HS + R+ R R DR
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDR 571
Score = 30.8 bits (68), Expect = 1.3
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 9/90 (10%)
Query: 167 RKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEK------KKKDK---EHRRPAEATSS 217
++ + D S +RK++KEKK K + + KE+ +K DK + ++ A++ S
Sbjct: 402 KERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461
Query: 218 PTSPERPRHHHHDSDSNSPCCKRRKRGHSG 247
S E+ + DS N KR + G
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKG 491
Score = 30.0 bits (66), Expect = 2.1
Identities = 15/75 (20%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 160 TSAASARRKPRAEDQTESSCESHRKSKKEK----KKKKKRKHKKEKKKKDKEHRRPAEAT 215
T + P +++ E + H+ + KE+ +K K+K + KK+ K R
Sbjct: 407 TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKE 466
Query: 216 SSPTSPERPRHHHHD 230
S + +H+ ++
Sbjct: 467 KSKSKERDSKHNRNE 481
Score = 30.0 bits (66), Expect = 2.1
Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 168 KPRAEDQTESSCESHRKSKK---------EKKKKKKRKHKKEKKKKDKEHRRPAEATSSP 218
K RA+ ++ S + KSK+ EK+ + + K + + K+KE + ++
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQE 512
Query: 219 TSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSR 254
S + + +S SN + DRR+ SR
Sbjct: 513 RSRSKEKSKQLESKSNE---HDHSKSKEKDRRAQSR 545
Score = 28.1 bits (61), Expect = 8.2
Identities = 40/211 (18%), Positives = 75/211 (35%), Gaps = 24/211 (11%)
Query: 53 KGRAPCAGPSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEE 112
K RA S+ +E + +E + + +N +K+ SK E K + +
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKH------NRNEEKRMRSRSKGRDHENVKEKEKQSDS 506
Query: 113 KGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRK---P 169
KG D+ SR +++ +L H +S A S R+
Sbjct: 507 KGKDQ--------------ERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDIT 552
Query: 170 RAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHR-RPAEATSSPTSPERPRHHH 228
+ + S +S+ ++ + R H +++ + + HR R E S R R
Sbjct: 553 KGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTP 612
Query: 229 HDSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
+ +RR+ S +R R D+
Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKDK 643
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 28/150 (18%)
Query: 135 REDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKK 194
++D++ K S H + +S +S++S+ + + +ESS ES +K++K ++KK
Sbjct: 237 KKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSS---STETSESSSESESNNKEKKIQRKK 293
Query: 195 RKHKK---------EKKKKDKEHRRPAEATSS----PTSPERPRH------------HHH 229
RK K E+K K K+ + E +SS + E+PR H
Sbjct: 294 RKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHS 353
Query: 230 DSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
DSD S K +R+ S R H R
Sbjct: 354 DSDKKSRTHKHSPEKRGSERKEGSSRSHGR 383
Score = 37.4 bits (85), Expect = 0.013
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 183 RKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNS------- 235
R KK+KKK +K+K ++ + K K+H+ + ++SS +S S+S S
Sbjct: 230 RLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKI 289
Query: 236 PCCKRRKRGHSGDRRSPS 253
KR+K SG S S
Sbjct: 290 QRKKRKKNKCSGHNNSDS 307
Score = 31.2 bits (69), Expect = 0.96
Identities = 50/223 (22%), Positives = 77/223 (34%), Gaps = 18/223 (8%)
Query: 45 GRDLTWYAKGRAPCAGPSRE----EELAAVREAEREALLAALGYKNVKKQPTGLSKEDFA 100
GR+LT + A E E L ++ +++ LL L KK+ K+ F
Sbjct: 187 GRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ 246
Query: 101 EVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAK-LGLSVFTHHRVESGGPG 159
K + K S+S S S E + K + + + G
Sbjct: 247 ---KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHN 303
Query: 160 TSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPT 219
S + + K + E SH +EK K+K R K E ++D + S
Sbjct: 304 NSDSEEKDKSKKRKLHEELSSSHHN--REKAKEKPRFLKHESSREDSK-------WSHSD 354
Query: 220 SPERPRHHHHDSDSNSPCCKR-RKRGHSGDRRSPSRRWHDRGS 261
S ++ R H H + K R H + RS R GS
Sbjct: 355 SDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGS 397
Score = 29.6 bits (65), Expect = 2.8
Identities = 34/154 (22%), Positives = 61/154 (39%), Gaps = 9/154 (5%)
Query: 86 NVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSV----GRVAMSREDKEAA 141
N++ QP G+ + + + G L GL + S G + A
Sbjct: 113 NIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIA 172
Query: 142 KLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEK 201
++ S F R G T+ ++ +E + + E + ++K+K RK + +
Sbjct: 173 EMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLE 232
Query: 202 KKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNS 235
KKK K+ R+ + S R +H H S S+S
Sbjct: 233 KKKKKKDRKKKKFQKS-----RSKHKKHKSSSSS 261
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 45.8 bits (107), Expect = 4e-05
Identities = 23/74 (31%), Positives = 38/74 (51%)
Query: 130 RVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEK 189
+ M ++ K K + T R + T+ + ++ E + E E ++ +KEK
Sbjct: 39 KTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEK 98
Query: 190 KKKKKRKHKKEKKK 203
KKKKK+K KK+KKK
Sbjct: 99 KKKKKKKKKKKKKK 112
Score = 36.6 bits (83), Expect = 0.023
Identities = 15/41 (36%), Positives = 28/41 (68%)
Query: 174 QTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEA 214
+ E E ++ +KEK+K+K+++ KK+KKKK K+ ++ A
Sbjct: 75 EKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNA 115
Score = 36.2 bits (82), Expect = 0.030
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 9/100 (9%)
Query: 165 ARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKK---------KDKEHRRPAEAT 215
A K + ES+ + RK K KKKKKK+ K+KKK K K+ + T
Sbjct: 9 AMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKT 68
Query: 216 SSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRR 255
++ T+ E+ + + + K +++ ++ ++
Sbjct: 69 TTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKK 108
Score = 30.8 bits (68), Expect = 1.3
Identities = 17/96 (17%), Positives = 39/96 (40%)
Query: 160 TSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPT 219
T SA ++ R + T+ + KK+KK K+K + KK+ ++ T+
Sbjct: 17 TEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEK 76
Query: 220 SPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRR 255
E+ + + + K +K+ ++ ++
Sbjct: 77 EKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112
>gi|42718020 retinitis pigmentosa 9 [Homo sapiens]
Length = 221
Score = 45.1 bits (105), Expect = 6e-05
Identities = 21/45 (46%), Positives = 29/45 (64%)
Query: 173 DQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSS 217
D+ SS S +K KKKKKK KHKK KK+K K+ +R +++ S
Sbjct: 170 DEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKS 214
Score = 42.4 bits (98), Expect = 4e-04
Identities = 20/46 (43%), Positives = 28/46 (60%)
Query: 175 TESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTS 220
+ SS E K KK+KKK+K +K KKEKKKK K + +++ S
Sbjct: 175 SSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
Score = 42.0 bits (97), Expect = 5e-04
Identities = 18/46 (39%), Positives = 29/46 (63%)
Query: 162 AASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKE 207
++S+ + + + + + E H+K KKEKKKKKKRKHK K + +
Sbjct: 174 SSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSD 219
Score = 40.8 bits (94), Expect = 0.001
Identities = 20/50 (40%), Positives = 32/50 (64%), Gaps = 4/50 (8%)
Query: 172 EDQTESSC----ESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSS 217
ED++ SS E H+K KK++K KK++K KK+KKK+ + + E + S
Sbjct: 171 EDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
Score = 33.1 bits (74), Expect = 0.25
Identities = 15/48 (31%), Positives = 27/48 (56%)
Query: 160 TSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKE 207
+S++S+ K + + + + RK +K+KKKK+K K K + D E
Sbjct: 174 SSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 45.1 bits (105), Expect = 6e-05
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 14/124 (11%)
Query: 134 SREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKK- 192
+RE K+ A ++ R S + ++K + + S S R+ +K+ KK
Sbjct: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216
Query: 193 --------KKRKH-----KKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCK 239
KKRKH K ++K KDK+ +R T +P S R DS S+S +
Sbjct: 217 KHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR 276
Query: 240 RRKR 243
R R
Sbjct: 277 SRSR 280
Score = 44.7 bits (104), Expect = 8e-05
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 154 ESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAE 213
ES + ++K + +D+ S ES ++ KK KK+KH+ E + K ++HR P
Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGRRS-ESSSPRRERKKSSKKKKHRSESESKKRKHRSPTP 234
Query: 214 ATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSEA 263
+ + ++ + S + +P +R R S D S S R A
Sbjct: 235 KSKRKSKDKKRKRSR--STTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Score = 39.3 bits (90), Expect = 0.004
Identities = 43/190 (22%), Positives = 73/190 (38%), Gaps = 20/190 (10%)
Query: 46 RDLTWYAKGRAPCAGPSREE--ELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVC 103
+D+ K P P+ E +LA + E + E L AA G + + + A
Sbjct: 101 KDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREA 160
Query: 104 KREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAA 163
K+ +P K + S+ + ++ K+ + R ES P
Sbjct: 161 KQPAPEPP-KPYSLVRESSSSRSPTPKQKKKKKKKDRGR---------RSESSSPRRERK 210
Query: 164 SARRKPRAEDQTESSCESHR------KSKKEKKKKKKRKHKKEKKKKDKEHRRPA--EAT 215
+ +K + ++ES HR K K + KK+K+ + K + HR + A+
Sbjct: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270
Query: 216 SSPTSPERPR 225
SS TS R R
Sbjct: 271 SSDTSRSRSR 280
Score = 39.3 bits (90), Expect = 0.004
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 15/99 (15%)
Query: 168 KPRAEDQTESSCESHRKSKKEKKKKKKR---------KHKKEKKKKDKEHRRPAEATSSP 218
KP + + SS S +K+KKKKK R + +++K K K+HR +E+
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228
Query: 219 TSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWH 257
P+ D K+RKR S SRR H
Sbjct: 229 HRSPTPKSKRKSKD------KKRKRSRSTTPAPKSRRAH 261
Score = 39.3 bits (90), Expect = 0.004
Identities = 30/108 (27%), Positives = 45/108 (41%), Gaps = 9/108 (8%)
Query: 152 RVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRP 211
R S P T S R P ++ S + R+S+ +++ + + ++ R P
Sbjct: 561 RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Query: 212 AEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
A S SP R R S S SP R+ G S R+P+RR R
Sbjct: 621 ARRRSRTRSPVRRR-----SRSRSPA---RRSGRSRS-RTPARRGRSR 659
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 153 VESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPA 212
V S P + S+RR+ A + +S K + +R + +++K + RR
Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
Query: 213 EATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGS 261
+ SS ++ R + S S S +RR+ G RSP+R+ R S
Sbjct: 1790 RSGSSQSTSRRRQR----SRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
Score = 36.2 bits (82), Expect = 0.030
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 10/99 (10%)
Query: 164 SARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPER 223
S R P+ ++ SS E RK+K +++ R + + KK + R + + SSP S +
Sbjct: 713 SHSRTPQRRGRSGSSSE--RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
Query: 224 PRHHHHDS-DSNSPCCK-------RRKRGHSGDRRSPSR 254
R S +SPC K RR R S ++ SR
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR 809
Score = 36.2 bits (82), Expect = 0.030
Identities = 44/182 (24%), Positives = 65/182 (35%), Gaps = 31/182 (17%)
Query: 105 REGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVES-------GG 157
R G PE RL S SGS V A+ G + +
Sbjct: 1578 RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSR 1637
Query: 158 PGTSAASARRKPRAEDQTESSCESHRKSKKEKK----------------KKKKRKHKKEK 201
G+S+ P TESS E KS+ ++ +++ + E
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL 1697
Query: 202 KKKDKEHRRPAEATSSPTSPER--PRHHHHDSDSN------SPCCKRRKRGHSGDRRSPS 253
+K + RR A+SSP + R PRH S S+ S +RR+ S ++ S
Sbjct: 1698 TRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757
Query: 254 RR 255
RR
Sbjct: 1758 RR 1759
Score = 35.4 bits (80), Expect = 0.051
Identities = 48/181 (26%), Positives = 70/181 (38%), Gaps = 26/181 (14%)
Query: 55 RAPCAGPSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGD----P 110
R+ + P RE + ++ ++ R + K + PT SK + ++ P
Sbjct: 199 RSESSSPRRERKKSSKKKKHRSE---SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAP 255
Query: 111 EEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARR--- 167
+ + R SAS S + SR AAK H G S AS RR
Sbjct: 256 KSRRAHRSTSADSASSS--DTSRSRSRSAAAKT-------HTTALAGRSPSPASGRRGEG 306
Query: 168 -KPRAEDQTESSCESHRKSKKEKKKKKKRK--HKKEKKKKDKEHRRPAEATS-SPTSPER 223
P +E T S+ R S E K+ K+K KK+K RP+ + S T PE
Sbjct: 307 DAPFSEPGTTST---QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP 363
Query: 224 P 224
P
Sbjct: 364 P 364
Score = 33.5 bits (75), Expect = 0.19
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 8/146 (5%)
Query: 105 REGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAAS 164
REG PE R S+S S + S ++ S + S +S+ S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 165 -ARRKPRAEDQTESSCE---SHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATS---- 216
A+ P+A + S + R+S+ +K + + E RRP+ S
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 217 SPTSPERPRHHHHDSDSNSPCCKRRK 242
+S ER DS SP KRR+
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRR 2736
Score = 32.0 bits (71), Expect = 0.57
Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 5/105 (4%)
Query: 156 GGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEAT 215
G P A + + +E+S R K +K + + + + A+
Sbjct: 376 GSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHAS 435
Query: 216 SSPTSPE-RPRHHHHDSDSNSPCCKRRKRGHSGDRRS----PSRR 255
SSP SP+ P H S+SP K R G + +S PSRR
Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480
Score = 31.6 bits (70), Expect = 0.74
Identities = 36/151 (23%), Positives = 49/151 (32%), Gaps = 18/151 (11%)
Query: 105 REGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAAS 164
R G E K R S S S + SR + R S S A
Sbjct: 723 RSGSSSERKNKSRTSQRRSRSNSSPEMKKSR------------ISSRRSRSLSSPRSKAK 770
Query: 165 ARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPER- 223
+R R S C K K + ++ R + K K + R + ++SSP ++
Sbjct: 771 SRLSLRRSLSGSSPCP---KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS 827
Query: 224 --PRHHHHDSDSNSPCCKRRKRGHSGDRRSP 252
P H S S P K G SP
Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSP 858
Score = 31.2 bits (69), Expect = 0.96
Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 167 RKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRH 226
R P + SS E RK++ ++ + + + + HRR + SSP E+ R
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS-PSVSSPEPAEKSRS 1741
Query: 227 HHHDSDSNSPCCK-RRKRGHS------GDRRSPSR 254
++SP K +RG S G +RS SR
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSR 1776
Score = 30.8 bits (68), Expect = 1.3
Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 15/124 (12%)
Query: 149 THHRVESGGPGTSAASARR-----KPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKK 203
+ R + P T S R KPR ++ S +S++EK + +R+ + +
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRS------RSRREKTRTTRRRDRSGSSQ 1795
Query: 204 KDKEHRRPAEATSSPTSPERPRHHHHD----SDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
R+ + + S T R +H +S RR+RG S + +R R
Sbjct: 1796 STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR 1855
Query: 260 GSEA 263
S A
Sbjct: 1856 TSPA 1859
Score = 30.8 bits (68), Expect = 1.3
Identities = 28/122 (22%), Positives = 41/122 (33%), Gaps = 21/122 (17%)
Query: 155 SGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEA 214
S +S++S+ + + SS S S K + K ++P
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
Query: 215 TSSPTSPERPRHHHHDSD--SNSPCCKRR-------------------KRGHSGDRRSPS 253
SP +P DS S SP +RR +RG GD RSPS
Sbjct: 2672 ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
Query: 254 RR 255
+
Sbjct: 2732 HK 2733
Score = 30.0 bits (66), Expect = 2.1
Identities = 20/95 (21%), Positives = 32/95 (33%)
Query: 161 SAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTS 220
S S R P ++ S +S+ ++ R H + +++ + S TS
Sbjct: 678 SGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS 737
Query: 221 PERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRR 255
R R + S RR R S R R
Sbjct: 738 QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Score = 30.0 bits (66), Expect = 2.1
Identities = 34/151 (22%), Positives = 57/151 (37%), Gaps = 15/151 (9%)
Query: 110 PEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKP 169
P+ +G+ R S S R +R + + G S T R + + RR
Sbjct: 1765 PKPRGLQR-------SRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGG 1817
Query: 170 RA-EDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHH 228
++ + ES R S + ++ + + K+ + + P + + S SP H
Sbjct: 1818 SGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPAT----H 1873
Query: 229 HDSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
S S +P RR+ S R SP R R
Sbjct: 1874 RRSRSRTPLISRRR---SRSRTSPVSRRRSR 1901
Score = 28.9 bits (63), Expect = 4.8
Identities = 20/97 (20%), Positives = 37/97 (38%)
Query: 159 GTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSP 218
G+S RR A+ + + ++ + +K+KKKK RR ++
Sbjct: 148 GSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR 207
Query: 219 TSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRR 255
+ + H S+S S K R R+S ++
Sbjct: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKK 244
Score = 28.9 bits (63), Expect = 4.8
Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 152 RVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRP 211
R SG P+ +++SS +S K++ +++ + E K + R
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRR 1595
Query: 212 AEATSSPTSPERPR---HHHHDSDSN--------SPCCKRRKRGHSGDRRSPS 253
+ + SSP ++PR SDS+ +R + G S R PS
Sbjct: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
Score = 28.9 bits (63), Expect = 4.8
Identities = 32/128 (25%), Positives = 43/128 (33%), Gaps = 13/128 (10%)
Query: 146 SVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKD 205
S R ES S A R R ++ SS E KS+ ++ + + KD
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS---GSSPEVKD 1606
Query: 206 KEHRRPAEATSSPTSPE--------RPRHHHHDSDS--NSPCCKRRKRGHSGDRRSPSRR 255
K P + S +SPE PR S S P + S P R
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR 1666
Query: 256 WHDRGSEA 263
RGS +
Sbjct: 1667 TARRGSRS 1674
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 45.1 bits (105), Expect = 6e-05
Identities = 35/142 (24%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 121 LGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCE 180
+G A V M ++ AK+ +V E T + + E Q E
Sbjct: 201 VGDAQSRVDDHLMGKQHMGYAKIKATV--EELKEKLRKRTEEPDRDERLKKEKQEREERE 258
Query: 181 SHRKSKKEKKKKKKRKHKKEKKK---KDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPC 237
R+ ++E++++K+R+ ++E++K +D+E R+ + + S +S R D
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSR 318
Query: 238 CKRRKRGHSGDRRSPSRRWHDR 259
+ R+R S DRR R HDR
Sbjct: 319 SRERRRSRSRDRR--RSRSHDR 338
Score = 38.1 bits (87), Expect = 0.008
Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 26/201 (12%)
Query: 61 PSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLG 120
P R+E L ++ ERE + +++ +E+ E K D E + R
Sbjct: 241 PDRDERLKKEKQ-EREEREKEREREREERERKRRREEEERE--KERARDRERRKRSRSRS 297
Query: 121 LGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTE---- 176
S+ S R + SR+ H R S S + RR+ R+ D++E
Sbjct: 298 RHSSRTSDRRCSRSRD-------------HKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
Query: 177 SSCESHRKSKKE-----KKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHH-D 230
S R+SK K + K R ++++K K+KE R + SS S R + +
Sbjct: 345 SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
Query: 231 SDSNSPCCKRRKRGHSGDRRS 251
++S K G S D +S
Sbjct: 405 TESKESDTKNEVNGTSEDIKS 425
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 45.1 bits (105), Expect = 6e-05
Identities = 35/142 (24%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 121 LGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCE 180
+G A V M ++ AK+ +V E T + + E Q E
Sbjct: 201 VGDAQSRVDDHLMGKQHMGYAKIKATV--EELKEKLRKRTEEPDRDERLKKEKQEREERE 258
Query: 181 SHRKSKKEKKKKKKRKHKKEKKK---KDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPC 237
R+ ++E++++K+R+ ++E++K +D+E R+ + + S +S R D
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSR 318
Query: 238 CKRRKRGHSGDRRSPSRRWHDR 259
+ R+R S DRR R HDR
Sbjct: 319 SRERRRSRSRDRR--RSRSHDR 338
Score = 38.1 bits (87), Expect = 0.008
Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 26/201 (12%)
Query: 61 PSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLG 120
P R+E L ++ ERE + +++ +E+ E K D E + R
Sbjct: 241 PDRDERLKKEKQ-EREEREKEREREREERERKRRREEEERE--KERARDRERRKRSRSRS 297
Query: 121 LGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTE---- 176
S+ S R + SR+ H R S S + RR+ R+ D++E
Sbjct: 298 RHSSRTSDRRCSRSRD-------------HKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
Query: 177 SSCESHRKSKKE-----KKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHH-D 230
S R+SK K + K R ++++K K+KE R + SS S R + +
Sbjct: 345 SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
Query: 231 SDSNSPCCKRRKRGHSGDRRS 251
++S K G S D +S
Sbjct: 405 TESKESDTKNEVNGTSEDIKS 425
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 44.3 bits (103), Expect = 1e-04
Identities = 32/142 (22%), Positives = 57/142 (40%), Gaps = 9/142 (6%)
Query: 129 GRVAMSREDK-EAAKLGLSVFTHH--------RVESGGPGTSAASARRKPRAEDQTESSC 179
G V RE + + A+ G +HH R GG G + S RR+ R+ ++ S
Sbjct: 77 GAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRS 136
Query: 180 ESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCK 239
S +S+ + K + R + + R +++ SS S R R + P
Sbjct: 137 RSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVS 196
Query: 240 RRKRGHSGDRRSPSRRWHDRGS 261
+R+ +SP + + G+
Sbjct: 197 KRESKSRSRSKSPPKSPEEEGA 218
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/157 (28%), Positives = 66/157 (42%), Gaps = 15/157 (9%)
Query: 105 REGGDPEEKGVDRLLGLGSASGSVGRVAMSR--EDKEAAKLGLSVFTHHRVESGGPGTSA 162
R+ G+ E+K L S S + R E + A+ S HR + T +
Sbjct: 1809 RDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ-----TRS 1863
Query: 163 ASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPE 222
S R+ R ++ S R KEK+K R K K ++++ +R + + T
Sbjct: 1864 RSRSRRRRRSSRSRSKSRGRRSVSKEKRK---RSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 223 RPRHHHHDSDSNSPCCKRRKRGHSGDRR----SPSRR 255
R R S S++P +RR R G RR SPSRR
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRS-VGRRRSFSISPSRR 1956
Score = 40.0 bits (92), Expect = 0.002
Identities = 38/119 (31%), Positives = 45/119 (37%), Gaps = 26/119 (21%)
Query: 157 GPGTSAASARRKPRAEDQTESSCE-------------SHRKSKKEKKKKKKRKHKKE--- 200
G SAAS E +ESS E +H KSKK K + K K KK
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSS 1821
Query: 201 -----KKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSR 254
K+ K EH+ + TS R R S S S + R R S RR SR
Sbjct: 1822 LRSRSKRSKSSEHK-----SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR 1875
Score = 38.9 bits (89), Expect = 0.005
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 174 QTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDS 233
QT+ + E K K +K KK K K KK+KK+K+K+++R E + S T + +SDS
Sbjct: 96 QTDPTDEIPTK-KSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/157 (28%), Positives = 66/157 (42%), Gaps = 15/157 (9%)
Query: 105 REGGDPEEKGVDRLLGLGSASGSVGRVAMSR--EDKEAAKLGLSVFTHHRVESGGPGTSA 162
R+ G+ E+K L S S + R E + A+ S HR + T +
Sbjct: 1809 RDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ-----TRS 1863
Query: 163 ASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPE 222
S R+ R ++ S R KEK+K R K K ++++ +R + + T
Sbjct: 1864 RSRSRRRRRSSRSRSKSRGRRSVSKEKRK---RSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 223 RPRHHHHDSDSNSPCCKRRKRGHSGDRR----SPSRR 255
R R S S++P +RR R G RR SPSRR
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRS-VGRRRSFSISPSRR 1956
Score = 40.0 bits (92), Expect = 0.002
Identities = 38/119 (31%), Positives = 45/119 (37%), Gaps = 26/119 (21%)
Query: 157 GPGTSAASARRKPRAEDQTESSCE-------------SHRKSKKEKKKKKKRKHKKE--- 200
G SAAS E +ESS E +H KSKK K + K K KK
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSS 1821
Query: 201 -----KKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSR 254
K+ K EH+ + TS R R S S S + R R S RR SR
Sbjct: 1822 LRSRSKRSKSSEHK-----SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR 1875
Score = 38.9 bits (89), Expect = 0.005
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 174 QTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDS 233
QT+ + E K K +K KK K K KK+KK+K+K+++R E + S T + +SDS
Sbjct: 96 QTDPTDEIPTK-KSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 44.3 bits (103), Expect = 1e-04
Identities = 51/164 (31%), Positives = 72/164 (43%), Gaps = 27/164 (16%)
Query: 106 EGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAA-- 163
+G DP E + +G + R + R D A+ G + ++ E GG S
Sbjct: 604 QGLDPGEPNKSKEVG----GEKIVRSSGGRMDAPAS--GSACSGLNKQEPGGSHGSETED 657
Query: 164 SARRKPRAEDQTESSCESHRKSKKEK-KK--KKKRKHKK------------EKKKKDKEH 208
+ R P + E S +SHR KK+K KK K KRKHK EK KK K+
Sbjct: 658 TGRSLP---SKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKR 714
Query: 209 RRPAEATSSPTSPER-PRHHHHDSDSNSPCCKRRKRGHSGDRRS 251
+R +S+P ER P+ S S +P +RR+ RRS
Sbjct: 715 KRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRS 758
Score = 34.7 bits (78), Expect = 0.087
Identities = 43/199 (21%), Positives = 74/199 (37%), Gaps = 23/199 (11%)
Query: 72 EAEREALLAALGYKNVKKQPTGLSK-EDFAEVCKREGGDPEEKGVDRLLGLGSASGSVG- 129
+ E ++ A G K+ K++ K + A G PE G SGS
Sbjct: 694 DTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG----------SGSPAP 743
Query: 130 --RVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKK 187
R +++D + L + + + GG G+S+ + + SSC+ +K+
Sbjct: 744 PRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKR 803
Query: 188 EKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSG 247
+ H+ + D++ + SP + + DS S R R SG
Sbjct: 804 SSRS----SHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSE--HSRSRSRSG 857
Query: 248 DRRS---PSRRWHDRGSEA 263
R S SRR + S+A
Sbjct: 858 RRHSSHRSSRRSYSSSSDA 876
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 43.9 bits (102), Expect = 1e-04
Identities = 20/55 (36%), Positives = 32/55 (58%)
Query: 167 RKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSP 221
+KP+ +++ E ++ KKEK+KKK K KK+K +K+KE R + S P
Sbjct: 842 KKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPP 896
Score = 37.7 bits (86), Expect = 0.010
Identities = 19/69 (27%), Positives = 32/69 (46%)
Query: 154 ESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAE 213
E P S + K + + E + +K +KEKKK K K KK +K+K++ + +
Sbjct: 831 EKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKK 890
Query: 214 ATSSPTSPE 222
+ P E
Sbjct: 891 SKKQPPGSE 899
Score = 37.0 bits (84), Expect = 0.018
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 186 KKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKR 243
KK KK KKK K KE K++DKE ++ E SP P++ +H + K +K+
Sbjct: 839 KKSKKPKKKEKKHKE-KERDKEKKKEKEKKKSP-KPKKKKHRKEKEERTKGKKKSKKQ 894
Score = 33.1 bits (74), Expect = 0.25
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRP---AEATSSPTSPE 222
+ K + D+ + + +KS K KKKK +++ ++ K K K ++P EA P
Sbjct: 850 KHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPVQNG 909
Query: 223 RPRHHHHDSDSN 234
P +S+
Sbjct: 910 APEEEQLPPESS 921
Score = 32.0 bits (71), Expect = 0.57
Identities = 14/46 (30%), Positives = 25/46 (54%)
Query: 169 PRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEA 214
P ++ + E + K EK K++K++ +KEKK K + P E+
Sbjct: 719 PMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTES 764
Score = 30.8 bits (68), Expect = 1.3
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 180 ESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRH----HHHDSDSNS 235
+ RK +KEK+KK KR+H + D E PA+ T E P + D D N
Sbjct: 740 DKRRKKRKEKEKKGKRRHSSLPTESD-EDIAPAQQVDIVTE-EMPENALPSDEDDKDPND 797
Query: 236 P 236
P
Sbjct: 798 P 798
Score = 28.1 bits (61), Expect = 8.2
Identities = 13/44 (29%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 180 ESHRKSKKEKKKKKK-RKHKKEKKKKDKEHRRPAEATSSPTSPE 222
+ + K ++E++ ++K K K+ KK+K+KE + +S PT +
Sbjct: 722 DQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESD 765
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 43.9 bits (102), Expect = 1e-04
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPR 225
RR+ ED+ E K ++ +K+K H+K++K+K+K+H R E ER +
Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKE---KEREHERRK 124
Query: 226 HHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
H + D +R+KR R SRR DR
Sbjct: 125 RHREEQDKARREWERQKRREMA--REHSRRERDR 156
Score = 37.7 bits (86), Expect = 0.010
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 165 ARRKPRAEDQTESSCESHRKSK---KEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSP 221
+RR+ +Q E E RK + KE++++K+R+ + E+++K++E RR A
Sbjct: 150 SRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 209
Query: 222 ERPRHHHHDSDSNSPCCKRRKRGHSGDRRSP 252
+ S SP R+R GD R P
Sbjct: 210 DYSDKVKASHWSRSPPRPPRERFELGDGRKP 240
Score = 30.0 bits (66), Expect = 2.1
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 182 HRKSKKEKKKK------KKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNS 235
HRK +K K+KK K+R+H++ K+ ++++ + E H + D
Sbjct: 99 HRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLE 158
Query: 236 PCCKRRKR 243
++R+R
Sbjct: 159 QLERKRER 166
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 43.9 bits (102), Expect = 1e-04
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 166 RRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPR 225
RR+ ED+ E K ++ +K+K H+K++K+K+K+H R E ER +
Sbjct: 34 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKE---KEREHERRK 90
Query: 226 HHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDR 259
H + D +R+KR R SRR DR
Sbjct: 91 RHREEQDKARREWERQKRREMA--REHSRRERDR 122
Score = 37.7 bits (86), Expect = 0.010
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 165 ARRKPRAEDQTESSCESHRKSK---KEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSP 221
+RR+ +Q E E RK + KE++++K+R+ + E+++K++E RR A
Sbjct: 116 SRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 175
Query: 222 ERPRHHHHDSDSNSPCCKRRKRGHSGDRRSP 252
+ S SP R+R GD R P
Sbjct: 176 DYSDKVKASHWSRSPPRPPRERFELGDGRKP 206
Score = 30.0 bits (66), Expect = 2.1
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 182 HRKSKKEKKKK------KKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNS 235
HRK +K K+KK K+R+H++ K+ ++++ + E H + D
Sbjct: 65 HRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLE 124
Query: 236 PCCKRRKR 243
++R+R
Sbjct: 125 QLERKRER 132
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 43.5 bits (101), Expect = 2e-04
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 172 EDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDS 231
+D+ E E + + +++K + + +K + R+P S P SP RPR+ +
Sbjct: 279 DDEDEEDGEEENQKRYYLRQRKATVYYQAPLEKPRHQRKPNIFYSGPASPARPRYRLSSA 338
Query: 232 DSNSPCCKRRKRG----HSGDRRSPS 253
SP CKR R HS D S S
Sbjct: 339 GPRSPYCKRMNRRRHAIHSSDSTSSS 364
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 154 ESGGPGT-SAASARRKPRAEDQ-----TESSCESHRKSKKEKKKKKKRKHKKEKKKKDKE 207
E G G+ + A+ +P E Q E +S+ KSKKEKKK KRK KEKK+K K+
Sbjct: 1325 EKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1384
Query: 208 HRRPAEATSSPTSPERPR 225
++ + S S ++ +
Sbjct: 1385 AKKASTKDSESPSQKKKK 1402
Score = 39.3 bits (90), Expect = 0.004
Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 26/137 (18%)
Query: 83 GYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAK 142
G +V + T + + A+ K G E+KG GS+G E +E +
Sbjct: 1297 GEASVSPEKTSTTSKGKAKRDKASGDVKEKKG----------KGSLGSQGAKDEPEEELQ 1346
Query: 143 LGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKE-- 200
G+ GG ++ S + K +++ + + K KKEKKKK K+ K+
Sbjct: 1347 KGMGTV------EGGDQSNPKSKKEKKKSDKRKKD------KEKKEKKKKAKKASTKDSE 1394
Query: 201 --KKKKDKEHRRPAEAT 215
+KK K+ ++ AE T
Sbjct: 1395 SPSQKKKKKKKKTAEQT 1411
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 154 ESGGPGT-SAASARRKPRAEDQ-----TESSCESHRKSKKEKKKKKKRKHKKEKKKKDKE 207
E G G+ + A+ +P E Q E +S+ KSKKEKKK KRK KEKK+K K+
Sbjct: 1364 EKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1423
Query: 208 HRRPAEATSSPTSPERPR 225
++ + S S ++ +
Sbjct: 1424 AKKASTKDSESPSQKKKK 1441
Score = 39.3 bits (90), Expect = 0.004
Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 26/137 (18%)
Query: 83 GYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAK 142
G +V + T + + A+ K G E+KG GS+G E +E +
Sbjct: 1336 GEASVSPEKTSTTSKGKAKRDKASGDVKEKKG----------KGSLGSQGAKDEPEEELQ 1385
Query: 143 LGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKE-- 200
G+ GG ++ S + K +++ + + K KKEKKKK K+ K+
Sbjct: 1386 KGMGTV------EGGDQSNPKSKKEKKKSDKRKKD------KEKKEKKKKAKKASTKDSE 1433
Query: 201 --KKKKDKEHRRPAEAT 215
+KK K+ ++ AE T
Sbjct: 1434 SPSQKKKKKKKKTAEQT 1450
Score = 28.9 bits (63), Expect = 4.8
Identities = 39/206 (18%), Positives = 73/206 (35%), Gaps = 9/206 (4%)
Query: 19 EDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKGRAPCAGPSREEELAAVREAEREAL 78
E K + ++ GNS+ P G+ + G++P V E E E
Sbjct: 123 EKAKAETEKAGKTGNSMPHPA----TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGS 178
Query: 79 LAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDK 138
+ A G +P +S + +E V+ + A V ++S ++
Sbjct: 179 VPAFG---AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQ--VKASSVSTKES 233
Query: 139 EAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHK 198
A K + V G + A+R + E+++ESS E ++ + +
Sbjct: 234 PARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
Query: 199 KEKKKKDKEHRRPAEATSSPTSPERP 224
EK + + PA+ T + P
Sbjct: 294 SEKILQVRAASAPAKGTPGKGATPAP 319
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 154 ESGGPGT-SAASARRKPRAEDQ-----TESSCESHRKSKKEKKKKKKRKHKKEKKKKDKE 207
E G G+ + A+ +P E Q E +S+ KSKKEKKK KRK KEKK+K K+
Sbjct: 1401 EKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1460
Query: 208 HRRPAEATSSPTSPERPR 225
++ + S S ++ +
Sbjct: 1461 AKKASTKDSESPSQKKKK 1478
Score = 39.3 bits (90), Expect = 0.004
Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 26/137 (18%)
Query: 83 GYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAK 142
G +V + T + + A+ K G E+KG GS+G E +E +
Sbjct: 1373 GEASVSPEKTSTTSKGKAKRDKASGDVKEKKG----------KGSLGSQGAKDEPEEELQ 1422
Query: 143 LGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKE-- 200
G+ GG ++ S + K +++ + + K KKEKKKK K+ K+
Sbjct: 1423 KGMGTV------EGGDQSNPKSKKEKKKSDKRKKD------KEKKEKKKKAKKASTKDSE 1470
Query: 201 --KKKKDKEHRRPAEAT 215
+KK K+ ++ AE T
Sbjct: 1471 SPSQKKKKKKKKTAEQT 1487
Score = 28.9 bits (63), Expect = 4.8
Identities = 39/206 (18%), Positives = 73/206 (35%), Gaps = 9/206 (4%)
Query: 19 EDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKGRAPCAGPSREEELAAVREAEREAL 78
E K + ++ GNS+ P G+ + G++P V E E E
Sbjct: 123 EKAKAETEKAGKTGNSMPHPA----TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGS 178
Query: 79 LAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDK 138
+ A G +P +S + +E V+ + A V ++S ++
Sbjct: 179 VPAFG---AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQ--VKASSVSTKES 233
Query: 139 EAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHK 198
A K + V G + A+R + E+++ESS E ++ + +
Sbjct: 234 PARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
Query: 199 KEKKKKDKEHRRPAEATSSPTSPERP 224
EK + + PA+ T + P
Sbjct: 294 SEKILQVRAASAPAKGTPGKGATPAP 319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,160,219
Number of Sequences: 37866
Number of extensions: 639345
Number of successful extensions: 15549
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 495
Number of HSP's successfully gapped in prelim test: 380
Number of HSP's that attempted gapping in prelim test: 6823
Number of HSP's gapped (non-prelim): 4682
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.