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Search of human proteins with 109148542
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109148542 alanyl-tRNA synthetase [Homo sapiens]
(968 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109148542 alanyl-tRNA synthetase [Homo sapiens] 1926 0.0
gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 800 0.0
gi|13376886 alanyl-tRNA synthetase domain containing 1 isoform 2... 49 2e-05
gi|217416402 alanyl-tRNA synthetase domain containing 1 isoform ... 49 2e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 39 0.031
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 38 0.040
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 38 0.040
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 38 0.040
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 38 0.040
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 35 0.34
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 35 0.44
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 35 0.44
gi|33188443 microfilament and actin filament cross-linker protei... 35 0.44
gi|33188445 microfilament and actin filament cross-linker protei... 35 0.44
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 34 0.58
gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens] 34 0.58
gi|27597061 ubiquitin protein ligase E3 component n-recognin 2 [... 33 1.3
gi|65507253 hypothetical protein LOC55196 [Homo sapiens] 33 1.3
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 33 1.7
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 32 2.2
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 32 2.2
gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo s... 32 2.2
gi|50083279 centrosome protein 4 [Homo sapiens] 32 2.9
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 32 3.8
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 32 3.8
gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Hom... 32 3.8
gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Hom... 32 3.8
gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Hom... 32 3.8
gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Hom... 32 3.8
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 31 4.9
>gi|109148542 alanyl-tRNA synthetase [Homo sapiens]
Length = 968
Score = 1926 bits (4990), Expect = 0.0
Identities = 968/968 (100%), Positives = 968/968 (100%)
Query: 1 MDSTLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPS 60
MDSTLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPS
Sbjct: 1 MDSTLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPS 60
Query: 61 HPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALE 120
HPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALE
Sbjct: 61 HPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALE 120
Query: 121 LLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGD 180
LLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGD
Sbjct: 121 LLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGD 180
Query: 181 TGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDT 240
TGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDT
Sbjct: 181 TGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDT 240
Query: 241 GMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLAD 300
GMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLAD
Sbjct: 241 GMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLAD 300
Query: 301 HARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDA 360
HARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDA
Sbjct: 301 HARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDA 360
Query: 361 FPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGF 420
FPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGF
Sbjct: 361 FPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGF 420
Query: 421 PVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLDIYAIEELRARGLEV 480
PVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLDIYAIEELRARGLEV
Sbjct: 421 PVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLDIYAIEELRARGLEV 480
Query: 481 TDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGG 540
TDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGG
Sbjct: 481 TDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGG 540
Query: 541 QIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRP 600
QIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRP
Sbjct: 541 QIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRP 600
Query: 601 IMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMI 660
IMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMI
Sbjct: 601 IMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMI 660
Query: 661 EAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGSLTSV 720
EAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGSLTSV
Sbjct: 661 EAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGSLTSV 720
Query: 721 EFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAK 780
EFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAK
Sbjct: 721 EFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAK 780
Query: 781 VKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKR 840
VKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKR
Sbjct: 781 VKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKR 840
Query: 841 VLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKIT 900
VLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKIT
Sbjct: 841 VLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKIT 900
Query: 901 CLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQLATSFAQ 960
CLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQLATSFAQ
Sbjct: 901 CLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQLATSFAQ 960
Query: 961 LRLGDVKN 968
LRLGDVKN
Sbjct: 961 LRLGDVKN 968
>gi|38569417 alanyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
Length = 985
Score = 800 bits (2067), Expect = 0.0
Identities = 444/970 (45%), Positives = 615/970 (63%), Gaps = 36/970 (3%)
Query: 7 ASEIRQRFIDFFK-RNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAK 65
AS +R F++FF+ R+ H V S++ P DP+LLF NAGMNQFKPIFL T+DP MA
Sbjct: 39 ASAVRAAFLNFFRDRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAG 98
Query: 66 LSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFG-DYFKELACKMALELLTQ 124
R AN+QKC+RAGG HNDL+DVG+D+ HHTFFEMLG+W+FG +YFKE AC MA ELLTQ
Sbjct: 99 FRRVANSQKCVRAGGHHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKEEACNMAWELLTQ 158
Query: 125 EFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPC 184
+GIP ERL+++YF GD AGL+ DLE + IW +LG+ +++L ++NFWEMGDTGPC
Sbjct: 159 VYGIPEERLWISYFDGDPKAGLDPDLETRDIWLSLGVPASRVLSFGPQENFWEMGDTGPC 218
Query: 185 GPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGL 244
GPC+EIHYD GG A P ++E+WNLVF+Q+NREADG L+PLP++ +DTGMGL
Sbjct: 219 GPCTEIHYDLAGGVGA--------PQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGL 270
Query: 245 ERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHART 304
ERLV+VLQ K S YDTDLF P AIQ+G A PY G+VG D D AYRV+ADH RT
Sbjct: 271 ERLVAVLQGKHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGRTDTAYRVVADHIRT 330
Query: 305 ITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPEL 364
++V ++DG P +G VLRRILRRAVR++ E L A GF +LV VVV++LGDA+PEL
Sbjct: 331 LSVCISDGVFPGMSGPPLVLRRILRRAVRFSMEILKAPPGFLGSLVPVVVETLGDAYPEL 390
Query: 365 KKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAW--LLYDTYGFPV 422
+++ + ++++E+E FL +L RGRRI+DR +++LG S P + AW L G P+
Sbjct: 391 QRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGPSDMFPAEVAWSLSLCGDLGLPL 450
Query: 423 DLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDL----IMLDIYAIEELRARGL 478
D+ L+ EEKG+ +D G E +LAQ ++Q + E + + LD++A+ EL+ +G+
Sbjct: 451 DMVELMLEEKGVQLDSAGLE---RLAQEEAQHRARQAEPVQKQGLWLDVHALGELQRQGV 507
Query: 479 EVTDDSPKYNYHLDSSGSYVFENTVATVMALRREK-MFVEEVSTGQECGVVLDKTCFYAE 537
TDDSPKYNY L SGSY F A V+ L E V V GQ CG++LD+T FYAE
Sbjct: 508 PPTDDSPKYNYSLRPSGSYEFGTCEAQVLQLYTEDGTAVASVGKGQRCGLLLDRTNFYAE 567
Query: 538 QGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPR 597
QGGQ D GYLV+ + ++ F V AQV GG++LH L++GDQV L +DE
Sbjct: 568 QGGQASDRGYLVR---AGQEDVLFPVARAQVCGGFILHEAVAPECLRLGDQVQLHVDEAW 624
Query: 598 RRPIMSNHTATHILNFALRSVLGE-ADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIA 656
R M+ HTATH+LN+ALR LG +Q+GS + P++LR D T + ++ +Q++ E
Sbjct: 625 RLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTV 684
Query: 657 NEMIEAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGS 716
E + +AVY ++ PLA + GLR++ DE YPDPVRVVS+GVPV+ L DP+ A
Sbjct: 685 QEAVGQDEAVYMEEVPLALTAQVPGLRSL-DEVYPDPVRVVSVGVPVAHAL-DPASQAAL 742
Query: 717 LTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSV 776
TSVE C GTHL + G VI+ + ++KG R++AVTG +AQ+A +SL + +
Sbjct: 743 QTSVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKA 802
Query: 777 MEAKVKAQTAPNKDVQREIADLG---EALATAVIPQWQKDELRETLKSLKKVMDDLDRAS 833
++ + + R D+G EA+ TAV+PQWQ+ EL T+K L++ + R
Sbjct: 803 ATERLSLGSRDVAEALRLSKDIGRLIEAVETAVMPQWQRRELLATVKMLQRRANTAIRKL 862
Query: 834 KADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVD 893
+ + +KT++ ++ + PL++ + S S L + ++ +P TS +L +
Sbjct: 863 Q---MGQAAKKTQELLERHSKGPLIV-DTVSAESLSVLVKVVRQLCEQAPSTSVLLLS-P 917
Query: 894 NEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQ 953
GK+ C CQV Q A A W V M GK G V AQ TG L+ AL
Sbjct: 918 QPMGKVLCACQVAQGAMPT-FTAEAWALAVCSHMGGKAWGSRVVAQGTGSTTD-LEAALS 975
Query: 954 LATSFAQLRL 963
+A ++A +L
Sbjct: 976 IAQTYALSQL 985
>gi|13376886 alanyl-tRNA synthetase domain containing 1 isoform 2
[Homo sapiens]
Length = 525
Score = 48.9 bits (115), Expect = 2e-05
Identities = 61/267 (22%), Positives = 103/267 (38%), Gaps = 44/267 (16%)
Query: 517 EEVSTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHI 576
+EV +G + VVL+ T + E GGQ D G + + +V RG H
Sbjct: 148 KEVLSGFQ--VVLEDTVLFPEGGGQPDDRGTI----------NDISVLRVTRRGEQADHF 195
Query: 577 GTIYGDLKVGDQVWLFIDEPRRRPIMSNHTATHILN------FALRSVLGEADQKGSLVA 630
L G QV + +D RR M H+ H++ F L++ E + S +
Sbjct: 196 TQT--PLDPGSQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIE 253
Query: 631 PDRLRFDFTAKGAMSTQQIKKAEEIANEMIEAAKAVYTQDCPLAAAKAIQGLRAVFDETY 690
D +M+ +Q+ E+ NE I V ++ L + Q + +
Sbjct: 254 LDT--------PSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEVEQVSGRGLPDDH 305
Query: 691 PDPVRVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIR 750
P+RVV+I E +D C GTH+ N S I+ E K
Sbjct: 306 AGPIRVVNI-----EGVDS-----------NMCCGTHVSNLSDLQVIKILGTEKGKKNRT 349
Query: 751 RIVAVTGAEAQKALRKAESLKKCLSVM 777
++ ++G K + ++ +K L+ +
Sbjct: 350 NLIFLSGNRVLKWMERSHGTEKALTAL 376
>gi|217416402 alanyl-tRNA synthetase domain containing 1 isoform 1
[Homo sapiens]
Length = 586
Score = 48.9 bits (115), Expect = 2e-05
Identities = 61/267 (22%), Positives = 103/267 (38%), Gaps = 44/267 (16%)
Query: 517 EEVSTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHI 576
+EV +G + VVL+ T + E GGQ D G + + +V RG H
Sbjct: 209 KEVLSGFQ--VVLEDTVLFPEGGGQPDDRGTI----------NDISVLRVTRRGEQADHF 256
Query: 577 GTIYGDLKVGDQVWLFIDEPRRRPIMSNHTATHILN------FALRSVLGEADQKGSLVA 630
L G QV + +D RR M H+ H++ F L++ E + S +
Sbjct: 257 TQT--PLDPGSQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIE 314
Query: 631 PDRLRFDFTAKGAMSTQQIKKAEEIANEMIEAAKAVYTQDCPLAAAKAIQGLRAVFDETY 690
D +M+ +Q+ E+ NE I V ++ L + Q + +
Sbjct: 315 LDT--------PSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEVEQVSGRGLPDDH 366
Query: 691 PDPVRVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIR 750
P+RVV+I E +D C GTH+ N S I+ E K
Sbjct: 367 AGPIRVVNI-----EGVDS-----------NMCCGTHVSNLSDLQVIKILGTEKGKKNRT 410
Query: 751 RIVAVTGAEAQKALRKAESLKKCLSVM 777
++ ++G K + ++ +K L+ +
Sbjct: 411 NLIFLSGNRVLKWMERSHGTEKALTAL 437
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 38.5 bits (88), Expect = 0.031
Identities = 35/158 (22%), Positives = 67/158 (42%), Gaps = 10/158 (6%)
Query: 742 EEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEA 801
EE + + R V A+ AL+K L+ +S ++ ++++ A +++ DLGE
Sbjct: 1082 EEELQAALAR-VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 802 LATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKRVLEKTKQFIDSNPNQPLVILE 861
L K EL +TL S + SK + + +L+KT + + +
Sbjct: 1141 LEAL------KTELEDTLDS---TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMR 1191
Query: 862 MESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKI 899
+ + + L E L+ K T++NE G++
Sbjct: 1192 QKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGEL 1229
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 38.1 bits (87), Expect = 0.040
Identities = 40/179 (22%), Positives = 76/179 (42%), Gaps = 16/179 (8%)
Query: 758 AEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRE 817
A+ AL+K L+ +S ++ + ++ A +++ DLGE L K EL +
Sbjct: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL------KTELED 1157
Query: 818 TLKSLKKVMD-DLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALK 876
TL S + R + V K+ L++ + ++ + + + + + L E L+
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQE----MRQKHAQAVEELTEQLE 1213
Query: 877 LFKMHSPQTSAMLFTVDNE----AGKITCLCQVPQNAANRGLKASEWVQQV-SGLMDGK 930
FK T++ E AG++ L Q Q ++ K VQ++ S DG+
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1272
Score = 30.8 bits (68), Expect = 6.4
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 812 KDELRETLKSLKKVMDDLDRASKADVQKRV--LEKTKQFIDSNPNQPLVILE 861
K+EL T K LK M+DL +SK DV K V LEK+K+ +++ + LE
Sbjct: 1499 KEELERTNKMLKAEMEDL-VSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 38.1 bits (87), Expect = 0.040
Identities = 40/179 (22%), Positives = 76/179 (42%), Gaps = 16/179 (8%)
Query: 758 AEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRE 817
A+ AL+K L+ +S ++ + ++ A +++ DLGE L K EL +
Sbjct: 1111 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL------KTELED 1164
Query: 818 TLKSLKKVMD-DLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALK 876
TL S + R + V K+ L++ + ++ + + + + + L E L+
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQE----MRQKHAQAVEELTEQLE 1220
Query: 877 LFKMHSPQTSAMLFTVDNE----AGKITCLCQVPQNAANRGLKASEWVQQV-SGLMDGK 930
FK T++ E AG++ L Q Q ++ K VQ++ S DG+
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1279
Score = 30.8 bits (68), Expect = 6.4
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 812 KDELRETLKSLKKVMDDLDRASKADVQKRV--LEKTKQFIDSNPNQPLVILE 861
K+EL T K LK M+DL +SK DV K V LEK+K+ +++ + LE
Sbjct: 1506 KEELERTNKMLKAEMEDL-VSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 38.1 bits (87), Expect = 0.040
Identities = 40/179 (22%), Positives = 76/179 (42%), Gaps = 16/179 (8%)
Query: 758 AEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRE 817
A+ AL+K L+ +S ++ + ++ A +++ DLGE L K EL +
Sbjct: 1111 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL------KTELED 1164
Query: 818 TLKSLKKVMD-DLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALK 876
TL S + R + V K+ L++ + ++ + + + + + L E L+
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQE----MRQKHAQAVEELTEQLE 1220
Query: 877 LFKMHSPQTSAMLFTVDNE----AGKITCLCQVPQNAANRGLKASEWVQQV-SGLMDGK 930
FK T++ E AG++ L Q Q ++ K VQ++ S DG+
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1279
Score = 30.8 bits (68), Expect = 6.4
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 812 KDELRETLKSLKKVMDDLDRASKADVQKRV--LEKTKQFIDSNPNQPLVILE 861
K+EL T K LK M+DL +SK DV K V LEK+K+ +++ + LE
Sbjct: 1506 KEELERTNKMLKAEMEDL-VSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 38.1 bits (87), Expect = 0.040
Identities = 40/179 (22%), Positives = 76/179 (42%), Gaps = 16/179 (8%)
Query: 758 AEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRE 817
A+ AL+K L+ +S ++ + ++ A +++ DLGE L K EL +
Sbjct: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL------KTELED 1157
Query: 818 TLKSLKKVMD-DLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALK 876
TL S + R + V K+ L++ + ++ + + + + + L E L+
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQE----MRQKHAQAVEELTEQLE 1213
Query: 877 LFKMHSPQTSAMLFTVDNE----AGKITCLCQVPQNAANRGLKASEWVQQV-SGLMDGK 930
FK T++ E AG++ L Q Q ++ K VQ++ S DG+
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1272
Score = 30.8 bits (68), Expect = 6.4
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 812 KDELRETLKSLKKVMDDLDRASKADVQKRV--LEKTKQFIDSNPNQPLVILE 861
K+EL T K LK M+DL +SK DV K V LEK+K+ +++ + LE
Sbjct: 1499 KEELERTNKMLKAEMEDL-VSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 35.0 bits (79), Expect = 0.34
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 756 TGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQR--EIADLGEALATAVIPQWQKD 813
TG + +K R + L++ + + + +Q +++ E D E L A + D
Sbjct: 274 TGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMD 333
Query: 814 ELRETLKSLKKVMDDLDRASKADVQKRVL 842
R T+K ++KV++D D K+D+ + VL
Sbjct: 334 LFRSTMKPVQKVLEDSD-LKKSDIDEIVL 361
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 34.7 bits (78), Expect = 0.44
Identities = 42/179 (23%), Positives = 73/179 (40%), Gaps = 26/179 (14%)
Query: 746 AKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATA 805
+K + + G+E Q+ K ++ KK V + K KDV A+L +A A
Sbjct: 128 SKAVESLAEAGGSEIQRV--KEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFAGT 185
Query: 806 VIPQWQKDELRETLKSLKKVMD-DLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMES 864
+ + L L +KK+ + DL A D + R++E+ K + S
Sbjct: 186 ETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSK------------ 233
Query: 865 GASAKALNEALKLFKMHSPQTSAMLFTVDN-EAGKITCLCQVPQNAANRGLKASEWVQQ 922
+AL + LK + S M +N +G++ LC P+ R +A++ Q
Sbjct: 234 ----EALIQCLK------EEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQ 282
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 34.7 bits (78), Expect = 0.44
Identities = 42/179 (23%), Positives = 73/179 (40%), Gaps = 26/179 (14%)
Query: 746 AKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATA 805
+K + + G+E Q+ K ++ KK V + K KDV A+L +A A
Sbjct: 128 SKAVESLAEAGGSEIQRV--KEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFAGT 185
Query: 806 VIPQWQKDELRETLKSLKKVMD-DLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMES 864
+ + L L +KK+ + DL A D + R++E+ K + S
Sbjct: 186 ETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSK------------ 233
Query: 865 GASAKALNEALKLFKMHSPQTSAMLFTVDN-EAGKITCLCQVPQNAANRGLKASEWVQQ 922
+AL + LK + S M +N +G++ LC P+ R +A++ Q
Sbjct: 234 ----EALIQCLK------EEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQ 282
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 34.7 bits (78), Expect = 0.44
Identities = 38/174 (21%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 735 GAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQRE 794
G V++ +E + GI+ A + KALR E ++ + ++ + T ++V+ E
Sbjct: 4070 GEEVLLIQEKL-DGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEE 4128
Query: 795 IADLGEALATA-VIPQWQ--KDELRETLKSLKKVMDDLDRASKADVQKRVLEKTKQFID- 850
+A G T IPQ+Q + EL++ + + V+D ++ S+A + + V + ++ +D
Sbjct: 4129 LATSGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRA-LLELVPWRAREGLDK 4187
Query: 851 --SNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKITCL 902
S+ N+ ++ G ++ A++ + + A L V K+ L
Sbjct: 4188 LVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMAL 4241
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 34.7 bits (78), Expect = 0.44
Identities = 38/174 (21%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 735 GAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQRE 794
G V++ +E + GI+ A + KALR E ++ + ++ + T ++V+ E
Sbjct: 3568 GEEVLLIQEKL-DGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEE 3626
Query: 795 IADLGEALATA-VIPQWQ--KDELRETLKSLKKVMDDLDRASKADVQKRVLEKTKQFID- 850
+A G T IPQ+Q + EL++ + + V+D ++ S+A + + V + ++ +D
Sbjct: 3627 LATSGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRA-LLELVPWRAREGLDK 3685
Query: 851 --SNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKITCL 902
S+ N+ ++ G ++ A++ + + A L V K+ L
Sbjct: 3686 LVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMAL 3739
>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
Length = 425
Score = 34.3 bits (77), Expect = 0.58
Identities = 25/109 (22%), Positives = 51/109 (46%), Gaps = 14/109 (12%)
Query: 437 DMDGFEEERKLAQLKSQGKGAGGEDLIML--------------DIYAIEELRARGLEVTD 482
D +G EE++ + +++ Q + A G + + + + +A +E +G EVTD
Sbjct: 259 DENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKGGEVTD 318
Query: 483 DSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDK 531
S + H D + +N + + M EE+S+ QE V++++
Sbjct: 319 HSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQ 367
>gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens]
Length = 213
Score = 34.3 bits (77), Expect = 0.58
Identities = 25/109 (22%), Positives = 51/109 (46%), Gaps = 14/109 (12%)
Query: 437 DMDGFEEERKLAQLKSQGKGAGGEDLIML--------------DIYAIEELRARGLEVTD 482
D +G EE++ + +++ Q + A G + + + + +A +E +G EVTD
Sbjct: 24 DENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKGGEVTD 83
Query: 483 DSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDK 531
S + H D + +N + + M EE+S+ QE V++++
Sbjct: 84 HSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQ 132
>gi|27597061 ubiquitin protein ligase E3 component n-recognin 2 [Homo
sapiens]
Length = 1755
Score = 33.1 bits (74), Expect = 1.3
Identities = 45/221 (20%), Positives = 86/221 (38%), Gaps = 35/221 (15%)
Query: 728 LRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAP 787
L+ H + E+ + + VT QK + E+ K S++ Q AP
Sbjct: 921 LQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAP 980
Query: 788 NKDVQRE-----------IADLGEALATAVIPQWQ----KDELRETLKSLKKVMDDLDRA 832
+V ++ + + E+ T+ + + + ++ R+ K+ +K ++ R
Sbjct: 981 YLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARL 1040
Query: 833 SKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFT- 891
+ + ++ E + FID N LE+++ SA HSP S M T
Sbjct: 1041 RREKIMAQMSEMQRHFIDENKELFQQTLELDASTSA---------VLDHSPVASDMTLTA 1091
Query: 892 -------VDNEAGKITC-LCQVPQ--NAANRGLKASEWVQQ 922
V + +TC LCQ Q +R + + +VQ+
Sbjct: 1092 LGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQR 1132
>gi|65507253 hypothetical protein LOC55196 [Homo sapiens]
Length = 1747
Score = 33.1 bits (74), Expect = 1.3
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 26/181 (14%)
Query: 780 KVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQK 839
K K PNKDV ++ + LG++L+ P+ K +L+ K+ +D +V+K
Sbjct: 1335 KTKTAFLPNKDVYKKHSSLGQSLS----PEKIKLKLKSVSFKQKRKLDQ-GNVLDMEVKK 1389
Query: 840 RVLEKTKQFID-----------SNPNQPLVILE--MESGASAKALNEALKLFKMHSP--- 883
+ +K +Q SNPN+ ++ E + + S + K ++ +P
Sbjct: 1390 KKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEY 1449
Query: 884 -QTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATG 942
Q + N+A K C+ VP ++ + ++ S+ QV GK K S T
Sbjct: 1450 LQRQKHKEALSNKASKKICVKNVPCDSEH--MRPSKLAVQVESC--GKSNEKHSSGVQTS 1505
Query: 943 K 943
K
Sbjct: 1506 K 1506
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 32.7 bits (73), Expect = 1.7
Identities = 34/117 (29%), Positives = 60/117 (51%), Gaps = 15/117 (12%)
Query: 743 EAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEAL 802
E +AK R A G + Q+AL + S+ ++ ++AK++ A +++ DLGE L
Sbjct: 271 EEMAKSSRASAARVG-QLQEALNERHSI---INALKAKLQMTEAALALSEQKAQDLGELL 326
Query: 803 ATA-----VIPQWQKDELR----ETLKSLKKVMDDLDRASKAD--VQKRVLEKTKQF 848
ATA + Q Q EL+ E + K++ DL A++ + +Q +V E ++F
Sbjct: 327 ATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKF 383
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 32.3 bits (72), Expect = 2.2
Identities = 27/115 (23%), Positives = 57/115 (49%), Gaps = 23/115 (20%)
Query: 788 NKDVQREIADLGEALATAVIPQWQKDELRETLKSLK-KVMDDLDRAS------------- 833
NK++Q EI+DL E L ++ + +++R+ L++ K ++ L+ A
Sbjct: 1502 NKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRA 1561
Query: 834 -------KADVQKRVLEKTKQFIDSNPNQPLVI--LEMESGASAKALNEALKLFK 879
KA++++++ EK ++ + N V+ L+ A ++ NEAL++ K
Sbjct: 1562 QLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK 1616
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 32.3 bits (72), Expect = 2.2
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Query: 743 EAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADL---- 798
E++A G+ A+ AQ RKAE+L L K++AQ + +E+A
Sbjct: 718 ESLASGVAEQEALREEVAQLR-RKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAE 776
Query: 799 GEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQ 838
EA A W++ LRE +++ + ++ + +A V+
Sbjct: 777 AEAHREAEAQAWEQARLREAVEAAGQELESASQEREALVE 816
>gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo
sapiens]
Length = 1079
Score = 32.3 bits (72), Expect = 2.2
Identities = 39/160 (24%), Positives = 59/160 (36%), Gaps = 16/160 (10%)
Query: 770 LKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDL 829
LK+ S++ V+ ++ QR I G+ + ++ L E K K
Sbjct: 778 LKQYRSLILRFVREWSSLTAMKQRIIRKSGQLFCSPILA------LEEITKQQTKQNCTK 831
Query: 830 DRASKADVQKRVLEKTKQF--------IDSNPNQPLVILEMESGASAKALNE-ALKLFKM 880
+K DV ++K K +S P P +E GA LN ++
Sbjct: 832 RYITKEDVAVASMDKVKNVGGHVRLITKESRPRDPFTKKLLEDGACVPFLNPYTVQADLT 891
Query: 881 HSPQTS-AMLFTVDNEAGKITCLCQVPQNAANRGLKASEW 919
P TS L VDNE + CQ P + KA+ W
Sbjct: 892 VKPSTSKGYLQAVDNEGNPLCLRCQQPTCQTKQACKANSW 931
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 32.0 bits (71), Expect = 2.9
Identities = 35/156 (22%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 749 IRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEAL----AT 804
I ++ V Q+ ++ L++ L++ME+ V+ + + +REI L AL +
Sbjct: 195 IADLLQVADNRIQELQQEVHQLQEKLAMMESGVRDYSKQIELREREIERLSVALDGGRSP 254
Query: 805 AVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKRVLE--KTKQFIDSNPNQPLVILEM 862
V+ +++ E L + + D + + D++KR+ E +TK+ + S +V L
Sbjct: 255 DVLSLESRNKTNEKLIAHLNIQVDFLQQANKDLEKRIRELMETKETVTSE----VVNLSN 310
Query: 863 ESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGK 898
++ + L E +L + +L T D E G+
Sbjct: 311 KNEKLCQELTEIDQLAQQLERHKEEVLETADKELGE 346
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 31.6 bits (70), Expect = 3.8
Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 3/66 (4%)
Query: 464 MLDIYAIEELRARGLEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQ 523
M+DI A +E A +++ D++ K + +SSG +F T+ + + REK +E + Q
Sbjct: 1122 MMDIVAAKE--AALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREK-DIEIDALSQ 1178
Query: 524 ECGVVL 529
+C +L
Sbjct: 1179 KCQTLL 1184
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 31.6 bits (70), Expect = 3.8
Identities = 48/203 (23%), Positives = 83/203 (40%), Gaps = 20/203 (9%)
Query: 778 EAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKA-D 836
EAK + Q A +K E+A T I + +EL E K L + + D + +A +
Sbjct: 1356 EAKAELQRAMSK-ANSEVAQWRTKYETDAIQR--TEELEEAKKKLAQRLQDAEEHVEAVN 1412
Query: 837 VQKRVLEKTKQFIDSNPNQPLVILEMESGASA------KALNEALKLFKMHSPQTSAMLF 890
+ LEKTKQ + + ++ +E + A A + ++ L +K +T A L
Sbjct: 1413 AKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELE 1472
Query: 891 TVDNEAGKITCLCQVPQNAANRGLKASEWV--------QQVSGLMD--GKGGGKDVSAQA 940
E+ ++ +NA L E + Q++S L + +GG + +
Sbjct: 1473 ASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1532
Query: 941 TGKNVGCLQEALQLATSFAQLRL 963
K V + LQ A A+ L
Sbjct: 1533 IKKQVEQEKSELQAALEEAEASL 1555
>gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Homo
sapiens]
Length = 3710
Score = 31.6 bits (70), Expect = 3.8
Identities = 48/228 (21%), Positives = 84/228 (36%), Gaps = 25/228 (10%)
Query: 364 LKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLL------YDT 417
+K P ++ ++ KT G + +++++L K+I W L T
Sbjct: 2159 IKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEIT 2218
Query: 418 YGFPVDLTGLIAEEKGLVVDMDGFEEE---------RKLAQLKSQGKGAGGEDL------ 462
F LI E G+VV+ E LA+ K G L
Sbjct: 2219 ESFKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVAD 2278
Query: 463 IMLDIYAIEELRARG---LEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEV 519
+ L ++ E+ A +E + ++N LD + V + ++ E +
Sbjct: 2279 VTLQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHI 2338
Query: 520 STGQECGVVLDKTCFYAEQG-GQIYDEGYLVKVDDSSEDKTEFTVKNA 566
S+G + + K+C + + EG D S +D+ FTVKNA
Sbjct: 2339 SSGNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNA 2386
>gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Homo
sapiens]
Length = 3585
Score = 31.6 bits (70), Expect = 3.8
Identities = 48/228 (21%), Positives = 84/228 (36%), Gaps = 25/228 (10%)
Query: 364 LKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLL------YDT 417
+K P ++ ++ KT G + +++++L K+I W L T
Sbjct: 2159 IKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEIT 2218
Query: 418 YGFPVDLTGLIAEEKGLVVDMDGFEEE---------RKLAQLKSQGKGAGGEDL------ 462
F LI E G+VV+ E LA+ K G L
Sbjct: 2219 ESFKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVAD 2278
Query: 463 IMLDIYAIEELRARG---LEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEV 519
+ L ++ E+ A +E + ++N LD + V + ++ E +
Sbjct: 2279 VTLQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHI 2338
Query: 520 STGQECGVVLDKTCFYAEQG-GQIYDEGYLVKVDDSSEDKTEFTVKNA 566
S+G + + K+C + + EG D S +D+ FTVKNA
Sbjct: 2339 SSGNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNA 2386
>gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Homo
sapiens]
Length = 3628
Score = 31.6 bits (70), Expect = 3.8
Identities = 48/228 (21%), Positives = 84/228 (36%), Gaps = 25/228 (10%)
Query: 364 LKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLL------YDT 417
+K P ++ ++ KT G + +++++L K+I W L T
Sbjct: 2202 IKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEIT 2261
Query: 418 YGFPVDLTGLIAEEKGLVVDMDGFEEE---------RKLAQLKSQGKGAGGEDL------ 462
F LI E G+VV+ E LA+ K G L
Sbjct: 2262 ESFKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVAD 2321
Query: 463 IMLDIYAIEELRARG---LEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEV 519
+ L ++ E+ A +E + ++N LD + V + ++ E +
Sbjct: 2322 VTLQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHI 2381
Query: 520 STGQECGVVLDKTCFYAEQG-GQIYDEGYLVKVDDSSEDKTEFTVKNA 566
S+G + + K+C + + EG D S +D+ FTVKNA
Sbjct: 2382 SSGNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNA 2429
>gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Homo
sapiens]
Length = 3753
Score = 31.6 bits (70), Expect = 3.8
Identities = 48/228 (21%), Positives = 84/228 (36%), Gaps = 25/228 (10%)
Query: 364 LKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLL------YDT 417
+K P ++ ++ KT G + +++++L K+I W L T
Sbjct: 2202 IKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEIT 2261
Query: 418 YGFPVDLTGLIAEEKGLVVDMDGFEEE---------RKLAQLKSQGKGAGGEDL------ 462
F LI E G+VV+ E LA+ K G L
Sbjct: 2262 ESFKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVAD 2321
Query: 463 IMLDIYAIEELRARG---LEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEV 519
+ L ++ E+ A +E + ++N LD + V + ++ E +
Sbjct: 2322 VTLQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHI 2381
Query: 520 STGQECGVVLDKTCFYAEQG-GQIYDEGYLVKVDDSSEDKTEFTVKNA 566
S+G + + K+C + + EG D S +D+ FTVKNA
Sbjct: 2382 SSGNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNA 2429
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 31.2 bits (69), Expect = 4.9
Identities = 37/156 (23%), Positives = 72/156 (46%), Gaps = 30/156 (19%)
Query: 754 AVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQ-- 811
AVTG + + +KAE LK+ +V TA N+ ++++ +L L + +
Sbjct: 1348 AVTGLQQEHDKQKAEELKQ-------QVDELTAANRKAEQDMRELTYELNALQLEKTSSE 1400
Query: 812 ------KDELRETLKSLKKVMDDLDRASKAD--VQKRVLEKTKQFIDSNPNQPLVILEME 863
KD+L ET +L+ + +L+R +A+ +++ E +Q L
Sbjct: 1401 EKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQ------------LNQT 1448
Query: 864 SGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKI 899
+G + +A+ EA L K+ L ++++E GK+
Sbjct: 1449 TGKAEEAMQEASDLKKI-KRNYQLELESLNHEKGKL 1483
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,611,418
Number of Sequences: 37866
Number of extensions: 1533331
Number of successful extensions: 3729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 3679
Number of HSP's gapped (non-prelim): 84
length of query: 968
length of database: 18,247,518
effective HSP length: 112
effective length of query: 856
effective length of database: 14,006,526
effective search space: 11989586256
effective search space used: 11989586256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.