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Search of human proteins with 108860690
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]
(631 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens] 1258 0.0
gi|68989256 ras inhibitor RIN1 [Homo sapiens] 54 6e-07
gi|52485606 formin-like 2 [Homo sapiens] 50 5e-06
gi|33356148 formin-like 1 [Homo sapiens] 49 1e-05
gi|40353729 Ras and Rab interactor 3 [Homo sapiens] 49 2e-05
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 49 2e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 47 7e-05
gi|18466802 Ras and Rab interactor 2 [Homo sapiens] 46 9e-05
gi|238776840 patatin-like phospholipase domain containing 1 isof... 45 2e-04
gi|224589138 patatin-like phospholipase domain containing 1 isof... 45 2e-04
gi|224593249 patatin-like phospholipase domain containing 1 isof... 45 2e-04
gi|239754138 PREDICTED: hypothetical protein [Homo sapiens] 45 2e-04
gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo ... 45 2e-04
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 45 2e-04
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 45 2e-04
gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo s... 44 5e-04
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 43 8e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 43 8e-04
gi|188497703 semaphorin 3F [Homo sapiens] 43 0.001
gi|153792074 proline rich 12 [Homo sapiens] 43 0.001
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 42 0.002
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 42 0.002
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 42 0.002
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 42 0.002
gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo ... 42 0.002
gi|40807465 zinc finger protein 341 [Homo sapiens] 42 0.002
gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens] 42 0.002
gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens] 42 0.002
gi|167621456 kinase suppressor of ras 2 [Homo sapiens] 42 0.002
gi|118402590 myosin XV [Homo sapiens] 40 0.005
>gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]
Length = 631
Score = 1258 bits (3256), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MAAAAGDGTVKPLQSAMKLANGAIELDTGNRPREAYTEYLRSIHYISQVLLEEVETTKEA 60
MAAAAGDGTVKPLQSAMKLANGAIELDTGNRPREAYTEYLRSIHYISQVLLEEVETTKEA
Sbjct: 1 MAAAAGDGTVKPLQSAMKLANGAIELDTGNRPREAYTEYLRSIHYISQVLLEEVETTKEA 60
Query: 61 GETVPPDTSKMLKLAQQCLERAQSTAAKLGKTRLKPTMPAAAPIPQPAGRHRRVYSDEGG 120
GETVPPDTSKMLKLAQQCLERAQSTAAKLGKTRLKPTMPAAAPIPQPAGRHRRVYSDEGG
Sbjct: 61 GETVPPDTSKMLKLAQQCLERAQSTAAKLGKTRLKPTMPAAAPIPQPAGRHRRVYSDEGG 120
Query: 121 KLSPFLPPEIFQKLQGAESQSCKKELTPLEEASLQNQKLKAAYEARMARLDPSQAMQKTS 180
KLSPFLPPEIFQKLQGAESQSCKKELTPLEEASLQNQKLKAAYEARMARLDPSQAMQKTS
Sbjct: 121 KLSPFLPPEIFQKLQGAESQSCKKELTPLEEASLQNQKLKAAYEARMARLDPSQAMQKTS 180
Query: 181 LTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAANRRFCSQVALTPEEREQRALYA 240
LTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAANRRFCSQVALTPEEREQRALYA
Sbjct: 181 LTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAANRRFCSQVALTPEEREQRALYA 240
Query: 241 AILEYEQDHDWPKHWKAKLKRNPGDLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALY 300
AILEYEQDHDWPKHWKAKLKRNPGDLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALY
Sbjct: 241 AILEYEQDHDWPKHWKAKLKRNPGDLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALY 300
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPV 360
PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPV
Sbjct: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPV 360
Query: 361 GSPSPLGDTASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAVEEIHNAVD 420
GSPSPLGDTASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAVEEIHNAVD
Sbjct: 361 GSPSPLGDTASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAVEEIHNAVD 420
Query: 421 RLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAALSRSMELY 480
RLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAALSRSMELY
Sbjct: 421 RLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAALSRSMELY 480
Query: 481 RNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQELGLLVLESCPQKKLECIVRTLRIIC 540
RNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQELGLLVLESCPQKKLECIVRTLRIIC
Sbjct: 481 RNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQELGLLVLESCPQKKLECIVRTLRIIC 540
Query: 541 VCAEDYCPTPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHE 600
VCAEDYCPTPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHE
Sbjct: 541 VCAEDYCPTPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHE 600
Query: 601 GYLIGEEGYCLTSLQSALSYVELLPRGGLAK 631
GYLIGEEGYCLTSLQSALSYVELLPRGGLAK
Sbjct: 601 GYLIGEEGYCLTSLQSALSYVELLPRGGLAK 631
>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
Length = 783
Score = 53.5 bits (127), Expect = 6e-07
Identities = 94/364 (25%), Positives = 135/364 (37%), Gaps = 88/364 (24%)
Query: 310 APGCCPPTPNPGSRRLRPSQSLH---CMLSPPEPSAAPR-PQDS----PPTPPLQPGPVG 361
+P PP P P PSQ+ C L E S R P S PP P LQ G
Sbjct: 258 SPPAVPPPPVPVLPGAVPSQTERLPPCQLLRRESSVGYRVPAGSGPSLPPMPSLQEVDCG 317
Query: 362 SPSPLGDTASGLPDKDSSFEDLEQFLGTSERQGRGRGV------------QPEPQLQQLK 409
SPS G+P S TS GR R + PE Q+ +
Sbjct: 318 SPS--SSEEEGVPGSRGS-------PATSPHLGRRRPLLRSMSAAFCSLLAPERQVGRAA 368
Query: 410 TAV-EEIHNAVDRLLSLTLLA---------FEGLNTAASKDRCLACIE---EPFFSP--- 453
A+ ++ H A +L+ L +G+ A S+ R + E E SP
Sbjct: 369 AALMQDRHTAAGQLVQDLLTQVRAGPEPQELQGIRQALSRARAMLSAELGPEKLLSPKRL 428
Query: 454 ---------------LWPLLLALYRSVHRAREAALSRSME---LYRNAPPTAIGIPTKLL 495
L P+L A R A + +L R E L R P A G L
Sbjct: 429 EHVLEKSLHCSVLKPLRPILAARLRR-RLAADGSLGRLAEGLRLARAQGPGAFGSHLSL- 486
Query: 496 PQNPEAKGATGYPYCAAAQELGLLVLESCPQKKLECIVRTLRIICVCAEDYCPTPEATPQ 555
P E + Q+L L+ P +++ +++ +++ + Q
Sbjct: 487 PSPVELE--------QVRQKLLQLLRTYSPSAQVKRLLQACKLLYMALRT---------Q 529
Query: 556 AGPPPIAAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQ 615
G GAD+ LP+LS V+ LP+L+ E + E + L GE GY LTSL
Sbjct: 530 EGE------GAGADEFLPLLSLVLAHCDLPELLLEAEYMSELLEPSLLTGEGGYYLTSLS 583
Query: 616 SALS 619
++L+
Sbjct: 584 ASLA 587
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 50.4 bits (119), Expect = 5e-06
Identities = 59/250 (23%), Positives = 98/250 (39%), Gaps = 12/250 (4%)
Query: 129 EIFQKLQGAESQSCKKELTPLEEASLQNQKLKAAYEARMARLDPSQAMQKTSLTLSLQRQ 188
E KL+ ES + ++ + L E + A L+ + +++ LS + Q
Sbjct: 351 EYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQ 410
Query: 189 MMENLVIAKAREETLQRKMEERRLRLQEAANRRFCSQVALTPE---EREQRALYAAILEY 245
EN ++K E Q + L + + +QV + E+E+ + LE
Sbjct: 411 DTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLE- 469
Query: 246 EQDHDWPKHWKAKL-KRNPGDLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVS 304
++ H+ K K+ K+ GD++++ + S LS+ +A SV + A S
Sbjct: 470 KKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGN------SVGPTMGAASS 523
Query: 305 RAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPS 364
P P PP+ + ++ M PP P P P PP PP PGP
Sbjct: 524 GPLPPPPPPLPPSSDT-PETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETV 582
Query: 365 PLGDTASGLP 374
P A LP
Sbjct: 583 PAPPLAPPLP 592
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 49.3 bits (116), Expect = 1e-05
Identities = 58/222 (26%), Positives = 95/222 (42%), Gaps = 31/222 (13%)
Query: 164 EARMARLDPSQAMQKTSLTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAANRRFC 223
E + A L+ + +Q+ L+ + + EN +AK E L++++ + R L E RF
Sbjct: 392 ETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAE--LEKQLSQARKEL-ETLRERFS 448
Query: 224 SQVAL----TPEEREQRALYA----AILEYEQDHDWPKHWKAKLKRNPGDLSLVTSLVSH 275
A+ P E E+ A + LE + + + + ++ R PGD ++ ++
Sbjct: 449 ESTAMGASRRPPEPEKAPPAAPTRPSALELKVE-ELEEKGLIRILRGPGD-AVSIEILPV 506
Query: 276 LLSLP---DHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNP--------GSRR 324
++ P D P + + P ++ AA PAPG PP P P +
Sbjct: 507 AVATPSGGDAPTPGVPT-------GSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPP 559
Query: 325 LRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPL 366
P Q+ SP P A P P D PP PP P P G+ P+
Sbjct: 560 SAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPV 601
>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
Length = 985
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/254 (22%), Positives = 107/254 (42%), Gaps = 32/254 (12%)
Query: 375 DKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAVEEIHNAVDRLLSLTLLAFEGLN 434
DK S F L Q + R LQ+++T + ++ + + + L L L+
Sbjct: 611 DKGSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVDPALH 670
Query: 435 TAASKDRCLACIEEPFFS-PLWPLLLALYRSVHR--AREAALSRSME---LYRNAPPTAI 488
S++ A +E + L PL A+ +H+ +++ +L + E + T +
Sbjct: 671 ---SEEELEAIVESALYKCVLKPLKEAINSCLHQIHSKDGSLQQLKENQLVILATTTTDL 727
Query: 489 GIPTKLLPQNPEAKGATGYPYCAAAQELGLLVLESCPQKKLECIVRTLRIICVCAEDYCP 548
G+ T + P+ P + Q+ + P+KK+ +++T ++I
Sbjct: 728 GVTTSV-PEVPMME--------KILQKFTSMHKAYSPEKKISILLKTCKLIY-------- 770
Query: 549 TPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEG 608
A G P GADD LP+L +V+ RS L +++ + E + +GE
Sbjct: 771 DSMALGNPGKP------YGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGS 824
Query: 609 YCLTSLQSALSYVE 622
Y LT+ AL +++
Sbjct: 825 YYLTTTYGALEHIK 838
Score = 32.0 bits (71), Expect = 1.8
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 28/84 (33%)
Query: 297 SALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSA-----APRPQDSPP 351
S P V A APAP C PT SPP P+ AP P D P
Sbjct: 293 SPAQPPVLPALAPAPACPLPT------------------SPPVPAPHVTPHAPGPPDHPN 334
Query: 352 TPPLQ-----PGPVGSPSPLGDTA 370
PP+ P P PL + A
Sbjct: 335 QPPMMTCERLPCPTAGLGPLREEA 358
>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
Length = 1050
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/168 (20%), Positives = 76/168 (45%), Gaps = 25/168 (14%)
Query: 454 LWPLLLALYRSVHRAREAALSRSMELYRNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAA 513
++ L+ ++ + +AA ++ ++ IG+ + P AK
Sbjct: 220 IYNLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAK----------- 268
Query: 514 QELGLLVLESCPQKKLECIVRTLRIICVCAEDYCPTPEATPQAGPPPIAAAAIGADDLLP 573
+EL L + PQ+KL C+ + +++I Q+ + + ADDLL
Sbjct: 269 RELAQLNKCTSPQQKLVCLRKVVQLIT--------------QSPSQRVNLETMCADDLLS 314
Query: 574 ILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYV 621
+L ++++++ +P ++ + ++ F E GYCLTS ++A+ Y+
Sbjct: 315 VLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIEYI 362
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 46.6 bits (109), Expect = 7e-05
Identities = 50/170 (29%), Positives = 71/170 (41%), Gaps = 25/170 (14%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPS-AAPRPQDSPPTPP----- 354
P +P P P +P P RL P + + PPE S +P P++SP +PP
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Query: 355 LQPGPVGSPS--PLGDTASGLPDKDSSFE-DLEQ--FLGTSER-----QGRGRGVQPEPQ 404
L P P SP+ P D+ + P +DS LE+ L E + G + P P+
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748
Query: 405 LQQLKTAVEEIHNAVDRLLSLTLLAFEGLNTAASKDRCLACI-EEPFFSP 453
L EE H L+ A E + ++ CL + EEP SP
Sbjct: 749 EPHLSPRPEEPH--------LSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790
Score = 37.7 bits (86), Expect = 0.032
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 11/84 (13%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPS----------AAPRPQDSP 350
P +P P P +P P + RL P + PPE S +P P+DSP
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP 634
Query: 351 PTPPLQPGPVGSPSPLGDTASGLP 374
+PP + P+ SP P S LP
Sbjct: 635 MSPPPEESPM-SPPPEVSRLSPLP 657
Score = 36.6 bits (83), Expect = 0.072
Identities = 76/380 (20%), Positives = 138/380 (36%), Gaps = 63/380 (16%)
Query: 44 HYISQVLLEE-------VETTKEAGET----VPPDTSKMLKLAQQCLERAQSTAAKLGKT 92
H + QV +++ V+T + G +PP + + L + Q + Q LG
Sbjct: 3746 HLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPA 3805
Query: 93 RLKPTMPAAAPIPQPAGRHRRVYSDEGGKLSPFLPPEIFQKLQGAESQSCKKELTPLEEA 152
++ P G HR+V + LS P++ Q+ QG L ++
Sbjct: 3806 QVAVLQQQHPGALGPQGPHRQVLMTQSRVLSS---PQLAQQGQGLMGH----RLVTAQQQ 3858
Query: 153 SLQNQKLKAAYEARMARLDPS----------QAMQKTSLT-LSLQRQMMENLVIAKAREE 201
Q Q + A ++ L S A SL L Q+Q+ + + + +++
Sbjct: 3859 QQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ 3918
Query: 202 TLQRKMEERRLRLQEAANRRFCSQVALTPEEREQRALYAAILEYEQDHDWPKHWKAKLKR 261
LQ++ + ++ +LQ+ Q L ++++Q L+ +Q + + + ++
Sbjct: 3919 QLQQQQQLQQQQLQQQQ-----QQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQ 3973
Query: 262 NPGDLSLVTSLVSHLL----------SLPDHPIAQL--------LRRLQCSVYSALYPAV 303
G L+ +L+S +P P+ L + + PAV
Sbjct: 3974 QMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAV 4033
Query: 304 SRAAAPAP----------GCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTP 353
S A P G P + ++PS S L +P P+P P
Sbjct: 4034 SSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQP 4093
Query: 354 PLQ-PGPVGSPSPLGDTASG 372
PL+ PG L TA G
Sbjct: 4094 PLRLPGQQQQQVSLLHTAGG 4113
Score = 35.8 bits (81), Expect = 0.12
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 308 APAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPS-AAPRPQDSPPTPPLQPGPVGSP--- 363
+P P P +P P + RL P M PPE S +P P+ S PP + P+ P
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614
Query: 364 SPL 366
SPL
Sbjct: 615 SPL 617
Score = 34.7 bits (78), Expect = 0.27
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSA-APRPQDSPPTPPLQPGP 359
PA+ +P P P +P L P PPE S +P P++SP +PP + P
Sbjct: 530 PALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESP 589
Query: 360 VGSP 363
+ P
Sbjct: 590 MSPP 593
Score = 34.3 bits (77), Expect = 0.36
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPV 360
P +P P P +P P S P + LSPPE S ++P +PP + P+
Sbjct: 488 PLEESPLSPPPEESPLSPPPESSPFSPLEE--SPLSPPEESPPSPALETPLSPPPEASPL 545
Query: 361 GSP---SPLGDTASGLP 374
P SPL LP
Sbjct: 546 SPPFEESPLSPPPEELP 562
Score = 33.9 bits (76), Expect = 0.47
Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 6/83 (7%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRL-RPSQSLHCMLSPPEPSAAPRPQDSPPTP----PL 355
P SR + P P P +P P + L RP + P E +P P+ SP +P PL
Sbjct: 462 PEASRLSPP-PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPL 520
Query: 356 QPGPVGSPSPLGDTASGLPDKDS 378
P PSP +T P + S
Sbjct: 521 SPPEESPPSPALETPLSPPPEAS 543
Score = 33.9 bits (76), Expect = 0.47
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQP 357
P PAP P P PG L P + P EP +P P++ P +P +P
Sbjct: 867 PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP 923
Score = 33.1 bits (74), Expect = 0.80
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 7/93 (7%)
Query: 299 LYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRP-QDSPPTPP--- 354
L P +P P P +P P + RL P PE RP ++SP +PP
Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500
Query: 355 --LQPGPVGSP-SPLGDTASGLPDKDSSFEDLE 384
L P P SP SPL ++ P++ LE
Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALE 533
Score = 31.6 bits (70), Expect = 2.3
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPS-AAPRPQDSPPTPP----- 354
P SR + P P P +P P + P + P E S +P P++SP +PP
Sbjct: 567 PEASRLSPP-PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
Query: 355 LQPGPVGSP 363
L P P SP
Sbjct: 626 LSPPPEDSP 634
Score = 30.8 bits (68), Expect = 4.0
Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 14/80 (17%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRR--LRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPG 358
P + + P G PTP P S + RPSQ P S P PPT P
Sbjct: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL------PSPSSQLPTEAQLPPTHP---- 4341
Query: 359 PVGSPSPLGDTASGLPDKDS 378
G+P P G T P + S
Sbjct: 4342 --GTPKPQGPTLEPPPGRVS 4359
Score = 30.4 bits (67), Expect = 5.2
Identities = 18/43 (41%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 334 MLSPPEPS-AAPRPQDSPPTPPLQPGPVGSPSPLGDTASGLPD 375
+L PPE S +P P++SP +PP + + SP P AS LP+
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRL-SPPPEELPASPLPE 481
Score = 30.0 bits (66), Expect = 6.7
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAA-PRPQDSPPTPPLQPGP 359
P +P P +P P + P M PPE S P ++SP +PP + P
Sbjct: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESP 616
Query: 360 VGSPSPLGDTASGLPD 375
+ SP P S P+
Sbjct: 617 L-SPPPEASRLSPPPE 631
Score = 30.0 bits (66), Expect = 6.7
Identities = 17/41 (41%), Positives = 18/41 (43%), Gaps = 7/41 (17%)
Query: 336 SPPEPSAAPRPQDSP-------PTPPLQPGPVGSPSPLGDT 369
SPP AP P P PT PL PV SP PL +
Sbjct: 4915 SPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASS 4955
>gi|18466802 Ras and Rab interactor 2 [Homo sapiens]
Length = 895
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 15/98 (15%)
Query: 525 PQKKLECIVRTLRIICVCAEDYCPTPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGL 584
P+KK+ ++R ++I E+ + GADD LP+L++V+ + +
Sbjct: 667 PEKKVMLLLRVCKLIYTVMENN---------------SGRMYGADDFLPVLTYVIAQCDM 711
Query: 585 PQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVE 622
+L +E + E + L GE GY LTS ALS ++
Sbjct: 712 LELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIK 749
>gi|238776840 patatin-like phospholipase domain containing 1 isoform
3 [Homo sapiens]
Length = 532
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Query: 267 SLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLR 326
S V++ VS L P P+A + +PAV + + PG PTP PG L
Sbjct: 341 SPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLS 400
Query: 327 PSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPL 366
P Q + SP + P + P P L P VG+P L
Sbjct: 401 PQQQVQPSGSPARSLHSQAP--TSPRPSLGPSTVGAPQTL 438
>gi|224589138 patatin-like phospholipase domain containing 1 isoform
2 [Homo sapiens]
Length = 446
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Query: 267 SLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLR 326
S V++ VS L P P+A + +PAV + + PG PTP PG L
Sbjct: 255 SPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLS 314
Query: 327 PSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPL 366
P Q + SP + P + P P L P VG+P L
Sbjct: 315 PQQQVQPSGSPARSLHSQAP--TSPRPSLGPSTVGAPQTL 352
>gi|224593249 patatin-like phospholipase domain containing 1 isoform
1 [Homo sapiens]
Length = 437
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Query: 267 SLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLR 326
S V++ VS L P P+A + +PAV + + PG PTP PG L
Sbjct: 246 SPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLS 305
Query: 327 PSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPL 366
P Q + SP + P + P P L P VG+P L
Sbjct: 306 PQQQVQPSGSPARSLHSQAP--TSPRPSLGPSTVGAPQTL 343
>gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]
Length = 274
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 285 AQLLRRLQCSVY---SALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPS 341
A+ L+R V+ S ++PA R+ P CPP P P SR PS L PP +
Sbjct: 8 AKFLKRHSKEVWKPSSLIHPA--RSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPR-A 64
Query: 342 AAPRPQDSPPTPPLQPGPVGSPSPLGDT 369
P+ PP PP P +G+ G T
Sbjct: 65 LPGSPEPPPPPPPAAPHVLGARVAAGPT 92
>gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo
sapiens]
Length = 274
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 285 AQLLRRLQCSVY---SALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPS 341
A+ L+R V+ S ++PA R+ P CPP P P SR PS L PP +
Sbjct: 8 AKFLKRHSKEVWKPSSLIHPA--RSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPR-A 64
Query: 342 AAPRPQDSPPTPPLQPGPVGSPSPLGDT 369
P+ PP PP P +G+ G T
Sbjct: 65 LPGSPEPPPPPPPAAPHVLGARVAAGPT 92
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 13/128 (10%)
Query: 258 KLKRNPG------DLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAP 311
+ +R PG D L+ V P P A +R + VY A VSR
Sbjct: 21 RYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFD 80
Query: 312 GCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPLGDTAS 371
P R RP PP P A PRP + P+PP PGP G + G S
Sbjct: 81 PPAAPRRRGSPERARPPP-------PPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRS 133
Query: 372 GLPDKDSS 379
K S
Sbjct: 134 DFLQKTGS 141
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 13/128 (10%)
Query: 258 KLKRNPG------DLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAP 311
+ +R PG D L+ V P P A +R + VY A VSR
Sbjct: 21 RYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFD 80
Query: 312 GCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPLGDTAS 371
P R RP PP P A PRP + P+PP PGP G + G S
Sbjct: 81 PPAAPRRRGSPERARPPP-------PPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRS 133
Query: 372 GLPDKDSS 379
K S
Sbjct: 134 DFLQKTGS 141
>gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo
sapiens]
Length = 1487
Score = 43.9 bits (102), Expect = 5e-04
Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 23/121 (19%)
Query: 508 PYCAAAQELGLLVLESCPQKKLECIVRT----LRIICVCAEDYCPTPEATPQAGPPPIAA 563
P+ +A E+ + P+ K++CI+R + ++ + ED P
Sbjct: 1382 PWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVP--------------- 1426
Query: 564 AAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVEL 623
GADD +P+L FV++++ P L+S + F + L GEE Y +A+ +++
Sbjct: 1427 ---GADDFVPVLVFVLIKANPPCLLSTVQYISSF-YASCLSGEESYWWMQFTAAVEFIKT 1482
Query: 624 L 624
+
Sbjct: 1483 I 1483
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 43.1 bits (100), Expect = 8e-04
Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 14/103 (13%)
Query: 316 PTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSP-PTPPLQPGPVGSPSPLGDTASGLP 374
PTP P ++ RP QS P P+ AP P +P PTP P P + +P G T +G P
Sbjct: 8 PTPAPAAQP-RPLQS---PAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGP 63
Query: 375 ---------DKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQL 408
D + L Q S+R+ + RG+ +L++L
Sbjct: 64 GVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKL 106
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 43.1 bits (100), Expect = 8e-04
Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 294 SVYSALYPAVSRAAA--PAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPS-AAPRPQDSP 350
+V + PA + A P P PP P+P PS S L PP P +P P SP
Sbjct: 385 AVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSP 444
Query: 351 PTPPLQPGPVGSPSPL 366
P PP Q SP P+
Sbjct: 445 PPPPAQEEQEESPPPV 460
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/103 (32%), Positives = 41/103 (39%), Gaps = 33/103 (32%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPT-------- 352
P + +P P CPP P P S PS PP P A ++SPP
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPS--------PPPPPAQEEQEESPPPVVPATCSR 467
Query: 353 ----PPLQP-----------GPVGS--PSPLGDTASGLPDKDS 378
PPL P GP G+ P+P TA+G P +DS
Sbjct: 468 KRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDS 510
Score = 32.0 bits (71), Expect = 1.8
Identities = 45/145 (31%), Positives = 52/145 (35%), Gaps = 13/145 (8%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRR--LRPSQ----SLHCMLSPPEPSAAPRPQDSPPTPP 354
P S AP P P P P RR LR SL L PP P+ P P SPP P
Sbjct: 579 PVPSPPRAPTPPSTP-VPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAP 637
Query: 355 LQPGPVGSPSPLGDTASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAVEE 414
S PL A ++ + E L T G +PEP A E
Sbjct: 638 ----ATSSRRPLLLRAPQFTPSEAHLKIYESVL-TPPPLGAPEAPEPEPPPADDSPAEPE 692
Query: 415 IHNAVDRLLSLTLLAFEGLNTAASK 439
AV R L+L F + T K
Sbjct: 693 -PRAVGRTNHLSLPRFAPVVTTPVK 716
Score = 30.4 bits (67), Expect = 5.2
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 10/54 (18%)
Query: 315 PPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSP--PTPPLQPGPVGSPSPL 366
PP P P + +L PP ++ P PQ+ P+PP P P +P PL
Sbjct: 551 PPKP--------PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 13/77 (16%)
Query: 294 SVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRP-----QD 348
+V++AL+P +S +A P PG PPTP P Q L +L+ PE + +
Sbjct: 701 AVHAALFPPLSMSAPPPPGAGPPTP--------PYQELAQLLAQPEVGLIHQYCQGYWRH 752
Query: 349 SPPTPPLQPGPVGSPSP 365
PP+P PG SP P
Sbjct: 753 VPPSPREAPGAPRSPEP 769
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 2/67 (2%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGP- 359
P AA P P P P+ S P L PP P AP PQ PP PP P P
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNG-TPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPA 1481
Query: 360 VGSPSPL 366
+ SP PL
Sbjct: 1482 LPSPPPL 1488
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPV 360
P + AP P PP P P + PS L P PS+ P P PP PP P P
Sbjct: 1457 PPPTPPPAPTPQPQPPPPPPPPQPALPSPP---PLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Query: 361 GSPSPLGDTASGLPDKDSS 379
P P + P++ ++
Sbjct: 1514 PPPPPAAAPLAAPPEEPAA 1532
Score = 38.9 bits (89), Expect = 0.015
Identities = 22/65 (33%), Positives = 24/65 (36%), Gaps = 3/65 (4%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPV 360
P + P P PP P P + P L P P AP P PP P P P
Sbjct: 1451 PLLEEKPPPTP---PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507
Query: 361 GSPSP 365
PSP
Sbjct: 1508 AMPSP 1512
Score = 34.3 bits (77), Expect = 0.36
Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Query: 299 LYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPG 358
L PA A P PP P P +L H L P PS RP++S P
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHG-LEPAAPSPRLRPEESLDPPGAMQE 882
Query: 359 PVGSPSPL----GDTASGLPDKD 377
+G+ PL GDT G P+ +
Sbjct: 883 LLGALEPLPPAPGDTGVGPPNSE 905
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 6/59 (10%)
Query: 301 PAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGP 359
P+ AP P PP P P P ++ PP P+AAP +PP P P P
Sbjct: 1483 PSPPPLVAPTPSSPPPPPLPPP----PPPAMPSPPPPPPPAAAPLA--APPEEPAAPSP 1535
Score = 31.6 bits (70), Expect = 2.3
Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
Query: 307 AAPAPGCCPPTPNPG--SRRLRPSQSLHCMLSPPEPSAAPRPQDS--PPTPPL 355
++P P PP P P S P + + +PPE AAP P+D P T PL
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546
Score = 30.4 bits (67), Expect = 5.2
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 25/87 (28%)
Query: 314 CPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQP--GPVGSPSPLGDTAS 371
CPP P P R R +P+ A R D PP P +P P+ P+ G ++
Sbjct: 1143 CPPNPGPDGPRRRGR----------KPTKAKR--DGPPRPRGRPRIRPLEVPTTAGPASA 1190
Query: 372 GLPDKDSSFEDLEQFLGTSERQGRGRG 398
P G + +GRGRG
Sbjct: 1191 STPTD-----------GAKKPRGRGRG 1206
>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2790
Score = 42.0 bits (97), Expect = 0.002
Identities = 75/296 (25%), Positives = 107/296 (36%), Gaps = 50/296 (16%)
Query: 300 YPAVSRAAAPAPGCCP------PTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTP 353
YP + A+ P P P PTP P +L PP PS P++ P
Sbjct: 2186 YPTATLASGPQPFLPPGKEATTPTPEPPLP----------LLPPPPPSEEEGPEEPPKAS 2235
Query: 354 PLQPGPVGSPSPLGD-TASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAV 412
P S L D +AS L + +S GTS G G GV ++ +T +
Sbjct: 2236 PESEACSLSAGDLSDSSASSLAEPESPGAG-----GTSGGPGGGTGVPDGMGQRRYRTQM 2290
Query: 413 EEIHNAVDRLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAA 472
+ L + +E T ++ C EE L ++ ++ RA+E
Sbjct: 2291 SSLQ------LKIMKACYEAYRTPTMQE-CEVLGEE---IGLPKRVIQVWFQNARAKE-- 2338
Query: 473 LSRSMELYRNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQEL-----GLLVLESCPQK 527
+ +L A + G LL A T PYC + G L K
Sbjct: 2339 --KKAKLQGTAAGSTGGSSEGLL-----AAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAK 2391
Query: 528 KLECIVRTLRIICVCAEDYCPTPEATPQAGPPPI---AAAAIGADDLLPILSFVVL 580
E + L+ C D P PEA P PP A+ +GA LP L+ V+L
Sbjct: 2392 LKEAVRAQLKSESKC-YDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLL 2446
>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 42.0 bits (97), Expect = 0.002
Identities = 75/296 (25%), Positives = 107/296 (36%), Gaps = 50/296 (16%)
Query: 300 YPAVSRAAAPAPGCCP------PTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTP 353
YP + A+ P P P PTP P +L PP PS P++ P
Sbjct: 2102 YPTATLASGPQPFLPPGKEATTPTPEPPLP----------LLPPPPPSEEEGPEEPPKAS 2151
Query: 354 PLQPGPVGSPSPLGD-TASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAV 412
P S L D +AS L + +S GTS G G GV ++ +T +
Sbjct: 2152 PESEACSLSAGDLSDSSASSLAEPESPGAG-----GTSGGPGGGTGVPDGMGQRRYRTQM 2206
Query: 413 EEIHNAVDRLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAA 472
+ L + +E T ++ C EE L ++ ++ RA+E
Sbjct: 2207 SSLQ------LKIMKACYEAYRTPTMQE-CEVLGEE---IGLPKRVIQVWFQNARAKE-- 2254
Query: 473 LSRSMELYRNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQEL-----GLLVLESCPQK 527
+ +L A + G LL A T PYC + G L K
Sbjct: 2255 --KKAKLQGTAAGSTGGSSEGLL-----AAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAK 2307
Query: 528 KLECIVRTLRIICVCAEDYCPTPEATPQAGPPPI---AAAAIGADDLLPILSFVVL 580
E + L+ C D P PEA P PP A+ +GA LP L+ V+L
Sbjct: 2308 LKEAVRAQLKSESKC-YDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLL 2362
>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 42.0 bits (97), Expect = 0.002
Identities = 75/296 (25%), Positives = 107/296 (36%), Gaps = 50/296 (16%)
Query: 300 YPAVSRAAAPAPGCCP------PTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTP 353
YP + A+ P P P PTP P +L PP PS P++ P
Sbjct: 2102 YPTATLASGPQPFLPPGKEATTPTPEPPLP----------LLPPPPPSEEEGPEEPPKAS 2151
Query: 354 PLQPGPVGSPSPLGD-TASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAV 412
P S L D +AS L + +S GTS G G GV ++ +T +
Sbjct: 2152 PESEACSLSAGDLSDSSASSLAEPESPGAG-----GTSGGPGGGTGVPDGMGQRRYRTQM 2206
Query: 413 EEIHNAVDRLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAA 472
+ L + +E T ++ C EE L ++ ++ RA+E
Sbjct: 2207 SSLQ------LKIMKACYEAYRTPTMQE-CEVLGEE---IGLPKRVIQVWFQNARAKE-- 2254
Query: 473 LSRSMELYRNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQEL-----GLLVLESCPQK 527
+ +L A + G LL A T PYC + G L K
Sbjct: 2255 --KKAKLQGTAAGSTGGSSEGLL-----AAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAK 2307
Query: 528 KLECIVRTLRIICVCAEDYCPTPEATPQAGPPPI---AAAAIGADDLLPILSFVVL 580
E + L+ C D P PEA P PP A+ +GA LP L+ V+L
Sbjct: 2308 LKEAVRAQLKSESKC-YDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLL 2362
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 315 PPTPNPGSRRLRPSQSLHCMLSPPEPSAAPR------PQDSPPTPPLQPGPVGSPSPLGD 368
PP P+ + + LH PP P+AAP PQ P PP QP P P LG
Sbjct: 72 PPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQP-PPPPPQQLGS 130
Query: 369 TASGLPDKDSSFEDLEQFLGTSE 391
AS SSF ++ LG S+
Sbjct: 131 AASAPRTSTSSFL-IKDILGDSK 152
>gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo
sapiens]
Length = 491
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Query: 568 ADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLI-GEEGYCLTSLQSALSYVELL 624
ADD LP L ++VL+ P+L S + F + L+ GE+GY T+L A++++E L
Sbjct: 312 ADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKL 369
>gi|40807465 zinc finger protein 341 [Homo sapiens]
Length = 847
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 20/151 (13%)
Query: 273 VSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLH 332
+S +++P P+ Q L + V + + A P P P ++ S ++H
Sbjct: 114 ISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQPMPQGPPP----VQSSLNMH 169
Query: 333 CMLS----------PPEPSAAPRPQDSPPTPPLQPGPVGSPSPLGDTASGLPDKDSSFED 382
+ S PP P P P PP PP GP G P+P G +G+ + S+
Sbjct: 170 SVPSYLTQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPPGRPNPGG---NGVVEVYSAAAP 226
Query: 383 LEQFLGTSERQGRGRGVQPEPQLQQLKTAVE 413
L G+ + + G+QP P L+ VE
Sbjct: 227 L---AGSGTVEIQALGMQPYPPLEVPNQCVE 254
>gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens]
Length = 1309
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 11/101 (10%)
Query: 277 LSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGC-CPPTPNPGSRRLRPSQSLHCML 335
+ +P+ + ++L+ L+ + V R APA GC PP P P + P + L
Sbjct: 1150 IKIPEGCVRRVLQELRL-----MDADVKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTY 1204
Query: 336 SPPEPSAAPRPQDSPPTP---PLQPG--PVGSPSPLGDTAS 371
SPP + P P S P P PG P+G+P D A+
Sbjct: 1205 SPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAA 1245
>gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens]
Length = 1366
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 11/101 (10%)
Query: 277 LSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGC-CPPTPNPGSRRLRPSQSLHCML 335
+ +P+ + ++L+ L+ + V R APA GC PP P P + P + L
Sbjct: 1207 IKIPEGCVRRVLQELRL-----MDADVKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTY 1261
Query: 336 SPPEPSAAPRPQDSPPTP---PLQPG--PVGSPSPLGDTAS 371
SPP + P P S P P PG P+G+P D A+
Sbjct: 1262 SPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAA 1302
>gi|167621456 kinase suppressor of ras 2 [Homo sapiens]
Length = 921
Score = 41.6 bits (96), Expect = 0.002
Identities = 64/259 (24%), Positives = 103/259 (39%), Gaps = 30/259 (11%)
Query: 134 LQGAESQ-SCKKELTPLEEASLQNQKLKAAYEARMARLDPSQAMQKTSLTLSLQRQMMEN 192
L+G ++ + +LT E +L+++ +K Y +R A+Q+ + L Q+
Sbjct: 9 LEGLRTKCATSNDLTQKEIRTLESKLVK--YFSRQLSCKKKVALQERNAELDGFPQLRHW 66
Query: 193 LVIAKAREETLQRKMEERRLRLQ---EAANRRFCSQVALTPEEREQRALYAAILEYEQD- 248
I R+E L+ ++ +L L+ E + + C V RE+ A A L ++
Sbjct: 67 FRIVDVRKEVLE-EISPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLSCLRNV 125
Query: 249 ---------HDWPKHW---KAKLKRNPGDLSLVTSLV-SHLLSLPDHPIAQLLRRLQCSV 295
DW W + + NP T + +HL P P + S
Sbjct: 126 HMSGGNLSKQDWTIQWPTTETGKENNPVCPPEPTPWIRTHLSQSPRVPSKCVQHYCHTSP 185
Query: 296 Y--SALYPAVSRAAAPA-PGCCPPTP-NPGSRRLRPS-QSLHCMLSPPEPSAAPRPQDSP 350
+ +Y V R A PG CPP P G R L PS + H + +PP P
Sbjct: 186 TPGAPVYTHVDRLTVDAYPGLCPPPPLESGHRSLPPSPRQRHAVRTPPRTPNIVTTVTPP 245
Query: 351 PTPPLQP----GPVGSPSP 365
TPP++ P G+P P
Sbjct: 246 GTPPMRKKNKLKPPGTPPP 264
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 40.4 bits (93), Expect = 0.005
Identities = 25/53 (47%), Positives = 26/53 (49%), Gaps = 8/53 (15%)
Query: 315 PPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDS--PPTPPLQPGPVGSPSP 365
PP P P R L +L LSPP P PRP S PP PPL P G P P
Sbjct: 644 PPAPQPAPRTLSHWSAL---LSPPVP---PRPPSSGPPPAPPLSPALSGLPRP 690
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,404,723
Number of Sequences: 37866
Number of extensions: 1669800
Number of successful extensions: 21164
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 922
Number of HSP's that attempted gapping in prelim test: 13642
Number of HSP's gapped (non-prelim): 6226
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.