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Search of human proteins with 10880975
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10880975 hypothetical protein LOC57821 [Homo sapiens]
(508 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10880975 hypothetical protein LOC57821 [Homo sapiens] 1015 0.0
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 71 2e-12
gi|88759339 aster-associated protein [Homo sapiens] 71 3e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 68 2e-11
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 65 1e-10
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 65 1e-10
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 65 1e-10
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 65 1e-10
gi|148746195 trichohyalin [Homo sapiens] 65 1e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 3e-10
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 63 6e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 62 1e-09
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 62 1e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 62 1e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 3e-09
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 61 3e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 59 1e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 1e-08
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 58 2e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 58 2e-08
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 57 3e-08
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 57 3e-08
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 57 3e-08
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 57 5e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 56 7e-08
gi|24307965 UBX domain containing 2 [Homo sapiens] 56 9e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 55 1e-07
gi|34878777 ring finger protein 20 [Homo sapiens] 55 2e-07
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 55 2e-07
>gi|10880975 hypothetical protein LOC57821 [Homo sapiens]
Length = 508
Score = 1015 bits (2624), Expect = 0.0
Identities = 508/508 (100%), Positives = 508/508 (100%)
Query: 1 MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVME 60
MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVME
Sbjct: 1 MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVME 60
Query: 61 HTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEED 120
HTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEED
Sbjct: 61 HTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEED 120
Query: 121 EEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFENER 180
EEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFENER
Sbjct: 121 EEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFENER 180
Query: 181 NMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLP 240
NMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLP
Sbjct: 181 NMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLP 240
Query: 241 PINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKT 300
PINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKT
Sbjct: 241 PINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKT 300
Query: 301 CPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERR 360
CPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERR
Sbjct: 301 CPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERR 360
Query: 361 KIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKK 420
KIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKK
Sbjct: 361 KIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKK 420
Query: 421 KHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLR 480
KHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLR
Sbjct: 421 KHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLR 480
Query: 481 LEAKRSKQLQHHLYMSEAKPFRFTDHYN 508
LEAKRSKQLQHHLYMSEAKPFRFTDHYN
Sbjct: 481 LEAKRSKQLQHHLYMSEAKPFRFTDHYN 508
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 71.2 bits (173), Expect = 2e-12
Identities = 46/151 (30%), Positives = 88/151 (58%), Gaps = 5/151 (3%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRA-K 397
+KE +K+ E +R+K +RE E+RK E EKE+KRE K +KK E+ + RR ++ K
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK 107
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQW 457
E E+ R+ ++ ++ R + K E+ +ER+ EE +++E K +ER K+
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER----KKEEREKERERKER 163
Query: 458 LRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+R+R + +++ +E+ R+ R + +R+++
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRK 194
Score = 64.3 bits (155), Expect = 2e-10
Identities = 40/151 (26%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R++E +K+ + +R K +++ ER+K E E++K+R + ++KR++ + R + +K
Sbjct: 69 RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK 128
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQW 457
E ++ +E R ++ R ++K EE+ KER+ +E +K+E K E +E+ K+
Sbjct: 129 EGKERERKEERKREE--RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 458 LRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+R+R K +++ R+ R+ + E K+ ++
Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEE 217
Score = 55.1 bits (131), Expect = 2e-07
Identities = 42/159 (26%), Positives = 84/159 (52%), Gaps = 9/159 (5%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQK-------KREQVLEM 390
++K+ +++ EE+ K +R E+ K EEKEK+++ + + K K E+ E
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 391 RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQE-ECLFFLKGTEG 449
R+ + K+ E RE ++ ++ R + +K EE+ KE++ +E +K+E K E
Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERER 202
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ER ++ R+K+ E+ E+Q R+ + + KR ++
Sbjct: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
Score = 51.2 bits (121), Expect = 2e-06
Identities = 47/206 (22%), Positives = 94/206 (45%), Gaps = 10/206 (4%)
Query: 306 VNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEE 365
V + S+ K N Q S ++ C P + ++ E + E K ++ R+ E +
Sbjct: 2 VKAISSRAAVKLNTELQMVSCSHISKP-CTQPGWQSEIREREREIETRKEGKKERESERK 60
Query: 366 KEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSR----ENRDPQQAFRLWLKKK 421
KE++ + ++KRE+ + ++ +R KE + R EN++ ++ + K+K
Sbjct: 61 KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK 120
Query: 422 HE-----EQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERT 476
E ++ KER+ +E RK+EE + E RE+ ++ R+KR K ++ +
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 477 RQLRLEAKRSKQLQHHLYMSEAKPFR 502
++ + KR + + E K R
Sbjct: 181 KERKERKKRERNRKERKKERERKERR 206
Score = 50.1 bits (118), Expect = 5e-06
Identities = 34/119 (28%), Positives = 65/119 (54%), Gaps = 1/119 (0%)
Query: 344 KQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMN 403
K+ +E+ K +R+ E RK E K+++RE + K +++R+QV E ++ KE ++
Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
Query: 404 SRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKR 462
RE R+ ++ + +K+ E+ KER+ +E RK+E +ER ++ RK+
Sbjct: 188 KRE-RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/96 (29%), Positives = 55/96 (57%), Gaps = 8/96 (8%)
Query: 338 RQKELQKQLEEKREKL---KREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
R+KE +++ +KRE+ ++EEER++ E ++ KKRE + + +K+RE+ R +
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERN---RKERKKERERKERRERKK 210
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQ 430
K+ E+ +D Q +R K++ + + KER+
Sbjct: 211 ERKKKEERKKERQKDRQTNWR--EKERGKRERKERK 244
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 70.9 bits (172), Expect = 3e-12
Identities = 141/618 (22%), Positives = 234/618 (37%), Gaps = 150/618 (24%)
Query: 10 KKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEEN---INQDLKENETVMEHTKRHS 66
++S EY DDF+ D +++ + SD S E + K+ N I+ D ++N + + K +
Sbjct: 39 QRSSEYSDDFDSDE--IVSLGDFSDTSADENSVNKKMNDFHISDDEEKNPSKLLFLKTNK 96
Query: 67 DPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEEVRRY 126
+DE V I+ + ++ E+ +S ESQ EE E ++++
Sbjct: 97 SNGNITKDE---------PVCAIKNEEEMAPDGCEDIVVKSFSESQNKDEEFEKDKIKMK 147
Query: 127 IMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFENERNMFGKL 186
+I+ + N+ + FK P K++ E + + K
Sbjct: 148 PKPRILS---IKSTSSAENNSLDTDDHFKPS------PRPRSMLKKKSHMEEKDGLEDKE 198
Query: 187 SQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELL------NLQDIASQGFLP 240
+ L + L NG E + + D + L +L+ I F P
Sbjct: 199 TALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQILGDSFSP 258
Query: 241 PINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVT-------------------- 280
+ N++ DP + + + NS S KE+S + H T
Sbjct: 259 G-SEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTADDLEEEKA 317
Query: 281 -------HSSTGEPLAYIAQPPL--NRKTCPSSAVNSDRSKGNGKS-NHRTQSAHI---- 326
T +PL +Q L T S DR+ N KS N+R SA
Sbjct: 318 KAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASSASARLMT 377
Query: 327 --------------SPVTSTYCL--------SPRQKE--------------LQKQLEEKR 350
S TS++ L P QK+ Q+ LE+K
Sbjct: 378 SEFLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEPDRADNIRAAVYQEWLEKKN 437
Query: 351 ------EKLKR-EEERRKIEEEKEK--KRENDIV-FKAW---LQKKREQVLEMRRIQ--R 395
++KR E E +I+ E++K KRE + F+AW +K+ +++ +R++
Sbjct: 438 VYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKN 497
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKK----HEEQMKERQTEELRKQEE-----------C 440
K+ E+ N+ + QAF W +KK E+ KER+ E +KQ+E
Sbjct: 498 KKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNL 557
Query: 441 LFFLKGTEGRERAFKQWLRRKRMEKMAEQ-----------QAVRE-------RTRQLRLE 482
K E +E FKQ + K EK E+ QA+ E + +Q R+E
Sbjct: 558 TAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIE 617
Query: 483 AKRSKQLQHHLYMSEAKP 500
K+ K +H SEA P
Sbjct: 618 RKQKK--RHSFLESEALP 633
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/162 (27%), Positives = 95/162 (58%), Gaps = 7/162 (4%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R +E + ++ E+ EK++R+E+R + +E++ +++E ++ + L+++ EQ+ E +
Sbjct: 263 RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQ 322
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL--KGTEGRERAFK 455
E E M +E + +Q RLW + E+QM+E Q +++R QEE ++ + E ER +
Sbjct: 323 E-EKMREQEEKMWRQEERLW---EQEKQMRE-QEQKMRDQEERMWEQDERLREKEERMRE 377
Query: 456 QWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSE 497
Q ++ EKM E++ +RER +++R E + ++ + + E
Sbjct: 378 QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Score = 63.5 bits (153), Expect = 4e-10
Identities = 50/171 (29%), Positives = 94/171 (54%), Gaps = 18/171 (10%)
Query: 339 QKELQKQ-LEEKREKL----KREEERRKIEEEKEKKRENDIVFKAWLQKK---REQVLEM 390
+KE Q+Q L E++EKL K +E+ KI E++EK R+ + + W Q+K R++ +
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE---EMWGQEKKMWRQEKMRE 483
Query: 391 RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELR--KQEECLFFLKGTE 448
+ Q ++ E M +E + Q R+W + + + +ER E+ + +QEE + K T+
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 449 GRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+E+ K W + EKM E++ +RER +++R E + ++ + + E K
Sbjct: 544 EQEK--KTW---DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Score = 55.8 bits (133), Expect = 9e-08
Identities = 46/182 (25%), Positives = 96/182 (52%), Gaps = 29/182 (15%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKK--REQVLEMRRIQRAK 397
+E ++Q++E+ EK+ +EE+ + +EEK ++E + W Q+K REQ +MR +
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE----RLWEQEKQMREQEQKMRDQEERM 361
Query: 398 EIEDMNSREN----RDPQQAFRLWLKKKHEEQMKER-------------QTEELRKQEEC 440
+D RE R+ ++ + K + EE+++ER Q E+++KQEE
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 441 LFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKP 500
++ E E+ ++Q ++ EK+ EQ+ ++E+ ++ + ++ + Q ++ E K
Sbjct: 422 MW-----EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKM 475
Query: 501 FR 502
+R
Sbjct: 476 WR 477
Score = 55.5 bits (132), Expect = 1e-07
Identities = 40/158 (25%), Positives = 87/158 (55%), Gaps = 12/158 (7%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R +E +K++ E+ E ++ +EE+ + +EE ++E + L +++E++ E ++Q +
Sbjct: 393 RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 452
Query: 398 EIEDMNSRENRDPQQAF----RLWLKKKHEEQMKE--RQTEELRKQEECLFFLKGTEGRE 451
E + RD ++ + ++W ++K EQ + Q E++R QE+ K + E
Sbjct: 453 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ-----KMWDQEE 507
Query: 452 RAFKQWLR-RKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
R ++Q R R++ E+M EQ+ + ++ ++R E K +Q
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/157 (23%), Positives = 85/157 (54%), Gaps = 15/157 (9%)
Query: 341 ELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIE 400
E +++++E+ EK+ +EE+ +EE++K +E + + W Q+++ Q E + ++ +++
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM--WEQEEKMQEQEEKMWEQEEKMR 656
Query: 401 DMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRR 460
+ + ++ K + +E+ + Q E++R+QEE + G+E K W +
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM------RGQEE--KMWGQE 708
Query: 461 KRM----EKMAEQQAVRERTRQLR-LEAKRSKQLQHH 492
++M EKM Q+ +RE+ ++R + K ++L H
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745
Score = 52.8 bits (125), Expect = 7e-07
Identities = 44/144 (30%), Positives = 75/144 (52%), Gaps = 26/144 (18%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+++ + +Q E REK +R E+ K+ E++EK +E + + + +KK + E R Q K
Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER--EKKMREEEETMREQEEK 414
Query: 398 ---------EIEDMNSRENRDPQQAFRLWLKKKHEEQMKE--RQTEELRKQEECLFFLKG 446
E E+ ++ R P+Q +LW ++K +EQ ++ Q E++R QEE
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW----- 469
Query: 447 TEGRERAFKQWLRRKRMEKMAEQQ 470
G+E+ K W R EKM EQ+
Sbjct: 470 --GQEK--KMW----RQEKMREQE 485
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/167 (26%), Positives = 84/167 (50%), Gaps = 28/167 (16%)
Query: 343 QKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQ---------KKREQVLEMRRI 393
Q Q +E++ R+EE + +E+K +K+E K W Q K REQ +MRR
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEE----KMWRQEERLREQEGKMREQEEKMRRQ 281
Query: 394 Q-RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
+ R +E E +E R+ ++ R K + +E+ + Q E++ +QEE + RE+
Sbjct: 282 EKRLREQE----KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKM--------REQ 329
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
K W + +R+ + +Q +RE+ +++R + +R + L E +
Sbjct: 330 EEKMWRQEERLWEQEKQ--MREQEQKMRDQEERMWEQDERLREKEER 374
Score = 50.4 bits (119), Expect = 4e-06
Identities = 37/170 (21%), Positives = 86/170 (50%), Gaps = 17/170 (10%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+ +E + Q+ E+ EK++ +E+ K+ +++E+ E D ++ RE+ MR ++
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQ--KMWDQEERMWEQD-------ERLREKEERMREQKKMW 530
Query: 398 EIEDMNSRENRDPQQAFRLW---LKKKHEEQMKE-----RQTEELRKQEECLFFLKGTEG 449
+ E+ E + +Q + W K + EE+M+E R+ EE+ +++E + +
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
RE+ K W + ++M++ E+ +E + E + ++ + ++ E K
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Score = 49.7 bits (117), Expect = 6e-06
Identities = 36/164 (21%), Positives = 88/164 (53%), Gaps = 16/164 (9%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKR--EQVLEMRRIQR 395
+++ + +Q E REK +R E++K+ +++EK RE K Q+K+ +Q +MR +R
Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQEEKMREEK---KTQEQEKKTWDQEEKMREEER 561
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFK 455
+E E ++ R+ ++ R E++ K ++ EE +++E + + + +E+ K
Sbjct: 562 MRERE----KKMREEEEMMR-------EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Query: 456 QWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
W + ++M + E+ ++E+ + + ++ ++ + ++ E K
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Score = 49.3 bits (116), Expect = 8e-06
Identities = 39/170 (22%), Positives = 86/170 (50%), Gaps = 21/170 (12%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKIEEEK------EKKRENDIVFKAWLQKKREQVL 388
L +++ +++Q + +++ K EE++ E+EK EK RE + + + +KK +
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRER--EKKMREEE 573
Query: 389 EMRRIQRAK----------EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQE 438
EM R Q K + E M +E + +Q ++W + EE+M E++ E+ +++
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW---EQEEKMWEQEEEDKMQEQ 630
Query: 439 ECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
E + + + + +E+ K W + ++M + E+ +E Q + E R ++
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/175 (22%), Positives = 90/175 (51%), Gaps = 24/175 (13%)
Query: 341 ELQKQLEEKREKLKREEER------RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
E +KQ+ E+ +K++ +EER R E+E E+ RE + +++ + + E+ + R +
Sbjct: 342 EQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
+E E M +E + +Q +W E++ KE Q + L +Q+E L+ + + +E+
Sbjct: 401 MREEEETMREQEEKMQKQEENMW-----EQEEKEWQQQRLPEQKEKLW--EQEKMQEQEE 453
Query: 455 KQWLRRKRM----------EKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
K W + +++ +KM Q+ +RE+ Q+ + ++ + + ++ E +
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Score = 45.1 bits (105), Expect = 2e-04
Identities = 41/182 (22%), Positives = 91/182 (50%), Gaps = 31/182 (17%)
Query: 344 KQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM------RRIQRAK 397
++L ++R+ L E R I E+ KK+ ++ K L + + +++ R+++RAK
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
Query: 398 EI-----------------EDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEEC 440
+ E++ +E + +Q ++W + EE+++E Q ++R+QEE
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW---RQEERLRE-QEGKMREQEEK 277
Query: 441 LFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKP 500
+ + E R R ++ LR + E + EQ+ +RE+ Q++ + ++ + + + E K
Sbjct: 278 M---RRQEKRLREQEKELREQEKE-LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 501 FR 502
+R
Sbjct: 334 WR 335
Score = 32.3 bits (72), Expect = 1.0
Identities = 31/157 (19%), Positives = 68/157 (43%), Gaps = 21/157 (13%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQD--LKENETVME 60
E K +K E ED + E + ++ +K M ++E QD L+E E M
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQK-------MWDQEERMWEQDERLREKEERMR 524
Query: 61 HTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEED 120
K+ ++ +++E + + D E +E + +++ + E+
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEK------------KTWDQEEKMREEERMREREKKMREE 572
Query: 121 EEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQ 157
EE+ R EK+ + + ++ QE ++E K++ +++
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Score = 30.4 bits (67), Expect = 4.0
Identities = 29/158 (18%), Positives = 70/158 (44%), Gaps = 27/158 (17%)
Query: 1 MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVME 60
M E K T ++ + ++ + + E + E EK EM E+EE + + + E + E
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE---QEEKMRE 592
Query: 61 HTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEE-EE 119
++ + ++ +Q++ + + QE K+ Q++ ++ +E
Sbjct: 593 QEEKMWEQEEKMQEQ-----------------------EEKMWEQEEKMWEQEEEDKMQE 629
Query: 120 DEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQ 157
EE+ EK+ + + + QE ++E K++ +++
Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Score = 30.0 bits (66), Expect = 5.2
Identities = 33/163 (20%), Positives = 72/163 (44%), Gaps = 15/163 (9%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQD--LKENETVM- 59
E + + KK E E+ ++ E + + EK +M ++E Q+ ++E E M
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 60 EHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEE 119
+ +R + D+ L+++ R + + E QE + +++ + E
Sbjct: 356 DQEERMWEQDERLREKEERMR------------EQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 120 DEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLE 162
+EE R EK+ + + + QE +++R + K++L + E
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/154 (31%), Positives = 87/154 (56%), Gaps = 17/154 (11%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
RQ+EL++Q EE + + EE +R+ EEE ++++ + L+++REQ + +RR QR +
Sbjct: 751 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA-----LRRQREQEIALRR-QREE 804
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQ-EECLFFLKGTEGRERAFKQ 456
E E + ++A R +++ EE+ + +Q E LRKQ EE + + E +R ++
Sbjct: 805 E-------ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 857
Query: 457 WLRRKRMEKMAEQQAVRERTRQLR-LEAKRSKQL 489
R RME+ A + E R+ + LE +R K+L
Sbjct: 858 --NRLRMEEEAARLRHEEEERKRKELEVQRQKEL 889
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/151 (29%), Positives = 83/151 (54%), Gaps = 17/151 (11%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK-- 397
++L+K K E+ +RE E R EE+E+KR+ + L++++E++L ++ + K
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRRQQEEERKRR 774
Query: 398 EIEDMNSRENRDP---QQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
E E++ R+ + Q+ + L+++ EE+ +++Q E LR+ EE + E ER
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE-----RRREEEERRK 829
Query: 455 KQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
++ L RK+ E+ A + A E Q RLE R
Sbjct: 830 QEELLRKQ-EEEAAKWAREEEEAQRRLEENR 859
Score = 46.2 bits (108), Expect = 7e-05
Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 12/159 (7%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ--- 394
+Q+E ++LEE+R REEE R+ +EE +K+E + A +++ ++ LE R++
Sbjct: 809 QQEEALRRLEERR----REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 864
Query: 395 ---RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL--KGTEG 449
R + E+ R+ + Q+ L +++ +++ R ++ ++Q+ L T G
Sbjct: 865 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 924
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
++ + + Q+ ER RQLR E +R ++
Sbjct: 925 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 963
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 385 EQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL 444
EQ+ ++ + + AK ++ E ++ K EE+ ++RQ E R+QEE L
Sbjct: 718 EQLQQLEKAKAAKLEQERREAE-----------MRAKREEEERKRQEELRRQQEEILRRQ 766
Query: 445 KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ E + R ++ RRK+ E + Q+ R+ R E +R +Q
Sbjct: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 810
Score = 39.3 bits (90), Expect = 0.009
Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 11/114 (9%)
Query: 380 LQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEEL-RKQE 438
L+K + LE R R E+ E R Q+ L+++ EE ++ +Q EE R++E
Sbjct: 723 LEKAKAAKLEQER--REAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRREE 776
Query: 439 ECLFFLKGTEG--RERAFKQWLRRKRMEKMAEQQ--AVRERTRQLRLEAKRSKQ 488
E L K E R+R + LRR+R E+ +QQ A+R + R E +R KQ
Sbjct: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 830
Score = 37.7 bits (86), Expect = 0.025
Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 26/166 (15%)
Query: 335 LSPRQKELQKQLEEKREKLKREEER----RKIEEEKEKKRENDIVFKAWLQKKREQVLEM 390
L R++E +++ +++ K+EEE R+ EE + + EN + + + R + E
Sbjct: 817 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 876
Query: 391 RR----IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKE----------RQTEELRK 436
+R +QR KE+ R+ + Q+A R +++ ++Q+ + +Q+
Sbjct: 877 KRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
Query: 437 QEECLFFL----KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQ 478
Q + L K E RER ++ RR++ E M Q +++ +Q
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/154 (31%), Positives = 87/154 (56%), Gaps = 17/154 (11%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
RQ+EL++Q EE + + EE +R+ EEE ++++ + L+++REQ + +RR QR +
Sbjct: 778 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA-----LRRQREQEIALRR-QREE 831
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQ-EECLFFLKGTEGRERAFKQ 456
E E + ++A R +++ EE+ + +Q E LRKQ EE + + E +R ++
Sbjct: 832 E-------ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 884
Query: 457 WLRRKRMEKMAEQQAVRERTRQLR-LEAKRSKQL 489
R RME+ A + E R+ + LE +R K+L
Sbjct: 885 --NRLRMEEEAARLRHEEEERKRKELEVQRQKEL 916
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/151 (29%), Positives = 83/151 (54%), Gaps = 17/151 (11%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK-- 397
++L+K K E+ +RE E R EE+E+KR+ + L++++E++L ++ + K
Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRRQQEEERKRR 801
Query: 398 EIEDMNSRENRDP---QQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
E E++ R+ + Q+ + L+++ EE+ +++Q E LR+ EE + E ER
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE-----RRREEEERRK 856
Query: 455 KQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
++ L RK+ E+ A + A E Q RLE R
Sbjct: 857 QEELLRKQ-EEEAAKWAREEEEAQRRLEENR 886
Score = 46.2 bits (108), Expect = 7e-05
Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 12/159 (7%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ--- 394
+Q+E ++LEE+R REEE R+ +EE +K+E + A +++ ++ LE R++
Sbjct: 836 QQEEALRRLEERR----REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 891
Query: 395 ---RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL--KGTEG 449
R + E+ R+ + Q+ L +++ +++ R ++ ++Q+ L T G
Sbjct: 892 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 951
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
++ + + Q+ ER RQLR E +R ++
Sbjct: 952 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 990
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 385 EQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL 444
EQ+ ++ + + AK ++ E ++ K EE+ ++RQ E R+QEE L
Sbjct: 745 EQLQQLEKAKAAKLEQERREAE-----------MRAKREEEERKRQEELRRQQEEILRRQ 793
Query: 445 KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ E + R ++ RRK+ E + Q+ R+ R E +R +Q
Sbjct: 794 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 837
Score = 39.3 bits (90), Expect = 0.009
Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 11/114 (9%)
Query: 380 LQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEEL-RKQE 438
L+K + LE R R E+ E R Q+ L+++ EE ++ +Q EE R++E
Sbjct: 750 LEKAKAAKLEQER--REAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRREE 803
Query: 439 ECLFFLKGTEG--RERAFKQWLRRKRMEKMAEQQ--AVRERTRQLRLEAKRSKQ 488
E L K E R+R + LRR+R E+ +QQ A+R + R E +R KQ
Sbjct: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 857
Score = 37.7 bits (86), Expect = 0.025
Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 26/166 (15%)
Query: 335 LSPRQKELQKQLEEKREKLKREEER----RKIEEEKEKKRENDIVFKAWLQKKREQVLEM 390
L R++E +++ +++ K+EEE R+ EE + + EN + + + R + E
Sbjct: 844 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 903
Query: 391 RR----IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKE----------RQTEELRK 436
+R +QR KE+ R+ + Q+A R +++ ++Q+ + +Q+
Sbjct: 904 KRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
Query: 437 QEECLFFL----KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQ 478
Q + L K E RER ++ RR++ E M Q +++ +Q
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/154 (31%), Positives = 87/154 (56%), Gaps = 17/154 (11%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
RQ+EL++Q EE + + EE +R+ EEE ++++ + L+++REQ + +RR QR +
Sbjct: 757 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA-----LRRQREQEIALRR-QREE 810
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQ-EECLFFLKGTEGRERAFKQ 456
E E + ++A R +++ EE+ + +Q E LRKQ EE + + E +R ++
Sbjct: 811 E-------ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 863
Query: 457 WLRRKRMEKMAEQQAVRERTRQLR-LEAKRSKQL 489
R RME+ A + E R+ + LE +R K+L
Sbjct: 864 --NRLRMEEEAARLRHEEEERKRKELEVQRQKEL 895
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/151 (29%), Positives = 83/151 (54%), Gaps = 17/151 (11%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK-- 397
++L+K K E+ +RE E R EE+E+KR+ + L++++E++L ++ + K
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRRQQEEERKRR 780
Query: 398 EIEDMNSRENRDP---QQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
E E++ R+ + Q+ + L+++ EE+ +++Q E LR+ EE + E ER
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE-----RRREEEERRK 835
Query: 455 KQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
++ L RK+ E+ A + A E Q RLE R
Sbjct: 836 QEELLRKQ-EEEAAKWAREEEEAQRRLEENR 865
Score = 46.2 bits (108), Expect = 7e-05
Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 12/159 (7%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ--- 394
+Q+E ++LEE+R REEE R+ +EE +K+E + A +++ ++ LE R++
Sbjct: 815 QQEEALRRLEERR----REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 870
Query: 395 ---RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL--KGTEG 449
R + E+ R+ + Q+ L +++ +++ R ++ ++Q+ L T G
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 930
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
++ + + Q+ ER RQLR E +R ++
Sbjct: 931 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 969
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 385 EQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL 444
EQ+ ++ + + AK ++ E ++ K EE+ ++RQ E R+QEE L
Sbjct: 724 EQLQQLEKAKAAKLEQERREAE-----------MRAKREEEERKRQEELRRQQEEILRRQ 772
Query: 445 KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ E + R ++ RRK+ E + Q+ R+ R E +R +Q
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
Score = 39.3 bits (90), Expect = 0.009
Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 11/114 (9%)
Query: 380 LQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEEL-RKQE 438
L+K + LE R R E+ E R Q+ L+++ EE ++ +Q EE R++E
Sbjct: 729 LEKAKAAKLEQER--REAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRREE 782
Query: 439 ECLFFLKGTEG--RERAFKQWLRRKRMEKMAEQQ--AVRERTRQLRLEAKRSKQ 488
E L K E R+R + LRR+R E+ +QQ A+R + R E +R KQ
Sbjct: 783 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 836
Score = 37.7 bits (86), Expect = 0.025
Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 26/166 (15%)
Query: 335 LSPRQKELQKQLEEKREKLKREEER----RKIEEEKEKKRENDIVFKAWLQKKREQVLEM 390
L R++E +++ +++ K+EEE R+ EE + + EN + + + R + E
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 882
Query: 391 RR----IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKE----------RQTEELRK 436
+R +QR KE+ R+ + Q+A R +++ ++Q+ + +Q+
Sbjct: 883 KRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 437 QEECLFFL----KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQ 478
Q + L K E RER ++ RR++ E M Q +++ +Q
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/154 (31%), Positives = 87/154 (56%), Gaps = 17/154 (11%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
RQ+EL++Q EE + + EE +R+ EEE ++++ + L+++REQ + +RR QR +
Sbjct: 757 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEA-----LRRQREQEIALRR-QREE 810
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQ-EECLFFLKGTEGRERAFKQ 456
E E + ++A R +++ EE+ + +Q E LRKQ EE + + E +R ++
Sbjct: 811 E-------ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE 863
Query: 457 WLRRKRMEKMAEQQAVRERTRQLR-LEAKRSKQL 489
R RME+ A + E R+ + LE +R K+L
Sbjct: 864 --NRLRMEEEAARLRHEEEERKRKELEVQRQKEL 895
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/151 (29%), Positives = 83/151 (54%), Gaps = 17/151 (11%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK-- 397
++L+K K E+ +RE E R EE+E+KR+ + L++++E++L ++ + K
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEE------LRRQQEEILRRQQEEERKRR 780
Query: 398 EIEDMNSRENRDP---QQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
E E++ R+ + Q+ + L+++ EE+ +++Q E LR+ EE + E ER
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE-----RRREEEERRK 835
Query: 455 KQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
++ L RK+ E+ A + A E Q RLE R
Sbjct: 836 QEELLRKQ-EEEAAKWAREEEEAQRRLEENR 865
Score = 46.2 bits (108), Expect = 7e-05
Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 12/159 (7%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ--- 394
+Q+E ++LEE+R REEE R+ +EE +K+E + A +++ ++ LE R++
Sbjct: 815 QQEEALRRLEERR----REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 870
Query: 395 ---RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL--KGTEG 449
R + E+ R+ + Q+ L +++ +++ R ++ ++Q+ L T G
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 930
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
++ + + Q+ ER RQLR E +R ++
Sbjct: 931 QQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQR 969
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 385 EQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL 444
EQ+ ++ + + AK ++ E ++ K EE+ ++RQ E R+QEE L
Sbjct: 724 EQLQQLEKAKAAKLEQERREAE-----------MRAKREEEERKRQEELRRQQEEILRRQ 772
Query: 445 KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ E + R ++ RRK+ E + Q+ R+ R E +R +Q
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQ 816
Score = 39.3 bits (90), Expect = 0.009
Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 11/114 (9%)
Query: 380 LQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEEL-RKQE 438
L+K + LE R R E+ E R Q+ L+++ EE ++ +Q EE R++E
Sbjct: 729 LEKAKAAKLEQER--REAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRREE 782
Query: 439 ECLFFLKGTEG--RERAFKQWLRRKRMEKMAEQQ--AVRERTRQLRLEAKRSKQ 488
E L K E R+R + LRR+R E+ +QQ A+R + R E +R KQ
Sbjct: 783 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 836
Score = 37.7 bits (86), Expect = 0.025
Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 26/166 (15%)
Query: 335 LSPRQKELQKQLEEKREKLKREEER----RKIEEEKEKKRENDIVFKAWLQKKREQVLEM 390
L R++E +++ +++ K+EEE R+ EE + + EN + + + R + E
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 882
Query: 391 RR----IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKE----------RQTEELRK 436
+R +QR KE+ R+ + Q+A R +++ ++Q+ + +Q+
Sbjct: 883 KRKELEVQRQKEL----MRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 437 QEECLFFL----KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQ 478
Q + L K E RER ++ RR++ E M Q +++ +Q
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 65.1 bits (157), Expect = 1e-10
Identities = 46/174 (26%), Positives = 96/174 (55%), Gaps = 10/174 (5%)
Query: 339 QKELQKQLEEKREKLKREEERRK-------IEEEKEKKRENDIVFKAWLQKKREQV--LE 389
++E Q+Q E+++++ +EEE ++ + +E+EK +E + + LQ++ EQ+ LE
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 390 MRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEG 449
+ ++R ++ E+ + R QQ R +++ E+Q + R+ +E R+Q+E +
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLR-LEAKRSKQLQHHLYMSEAKPFR 502
+E +Q LRR++ E+ EQQ RE+ + R + +R +QL+ + + R
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Score = 64.7 bits (156), Expect = 2e-10
Identities = 49/176 (27%), Positives = 96/176 (54%), Gaps = 16/176 (9%)
Query: 333 YCLSPRQKELQKQ---LEEKREKLKREE-ERRKIEEEKEKKRENDIVFKAWLQKKREQVL 388
Y Q++L+K+ L+E+ E+L+REE E+R+ +E++ + RE + LQ++ EQ+L
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE-----QLQQEEEQLL 944
Query: 389 EMRRIQRAKEIEDMNSRENRDPQQAFRLWL------KKKHEEQMKERQTEELRKQEECLF 442
R +R ++ + R+++ QQ L +++ E + K R+ EEL+++EE L
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 443 FLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRL-EAKRSKQLQHHLYMSE 497
+ + R + +++ R+K + E+Q +RE + RL E +R + + L E
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
Score = 62.8 bits (151), Expect = 7e-10
Identities = 49/174 (28%), Positives = 96/174 (55%), Gaps = 12/174 (6%)
Query: 339 QKELQKQ---LEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQR 395
+KE +K+ L ++ EKL+ EE +R+ E ++E+++ + + ++++E+ + +R++R
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRK-QEECLFFLKGTEGRERAF 454
+++ E R+ Q+ R +++ EQ +ER+ ++LR+ QEE E E
Sbjct: 303 EQQLRRKQEEERREQQEERRE--QQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 455 KQWLRRKRMEKMAEQQAVRE----RTRQLRLE--AKRSKQLQHHLYMSEAKPFR 502
+Q LRR++ E+ EQQ RE R +QLR E +R +QL+ + + R
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
Score = 62.8 bits (151), Expect = 7e-10
Identities = 44/164 (26%), Positives = 88/164 (53%), Gaps = 15/164 (9%)
Query: 338 RQKELQKQLEEKRE-KLKREEERRKIEE----------EKEKKRENDIVFKAWLQKKREQ 386
R+++L+++ EE+RE +LKR+EE ++++ E+E++RE + K +K+ EQ
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ--LLKREEEKRLEQ 560
Query: 387 VLEMRRIQRAKE--IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL 444
+R++R +E + + RE QQ + +++ E+++K + E L ++E L
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 445 KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
K E E +Q L+ + E+ +QQ RE+ + KR ++
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/165 (29%), Positives = 95/165 (57%), Gaps = 11/165 (6%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
RQ+ELQ++ EE+ KL+R+E RR+ +EE+++++ + + L++K+E+ ++ +R +
Sbjct: 267 RQRELQEE-EEQLRKLERQELRRERQEEEQQQQR--LRREQQLRRKQEEERREQQEERRE 323
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQW 457
+ E +E R QQ R +++ E+Q++ Q EE R+Q+ L+ + ER +Q
Sbjct: 324 QQERREQQEERREQQ-LRREQEERREQQLRREQEEERREQQ-----LRREQEEERR-EQQ 376
Query: 458 LRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
LRR++ + EQQ RE+ + + +R +QL+ + + R
Sbjct: 377 LRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/169 (25%), Positives = 89/169 (52%), Gaps = 14/169 (8%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
L +++LQ++ +++ +L+ EEE+ + E +E +RE ++E+ + +R++
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE-----------RQEEEQQQQRLR 301
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRK-QEECLFFLKGTEGRERA 453
R +++ E R+ Q+ R +++ EQ +ER+ ++LR+ QEE E E
Sbjct: 302 REQQLRRKQEEERREQQEERR--EQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 454 FKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
+Q LRR++ E+ EQQ RE+ + + +R +QL+ + + R
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Score = 60.8 bits (146), Expect = 3e-09
Identities = 41/150 (27%), Positives = 72/150 (48%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
L R++E + + E + ++LKRE+E R+ + K ++ K +++ EQ L+ ++
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
R ++ E R R+ + R K EEQ + RQ + R+Q+E E E
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668
Query: 455 KQWLRRKRMEKMAEQQAVRERTRQLRLEAK 484
+Q L+R+ E+ EQ+ E Q R K
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIK 698
Score = 60.5 bits (145), Expect = 4e-09
Identities = 45/156 (28%), Positives = 88/156 (56%), Gaps = 16/156 (10%)
Query: 341 ELQKQLEEKREKLKREEERRKIEEEKEKK-RENDIVFKAWLQKKREQVLEMRRIQRAKEI 399
EL+++ E++++ +RE + R +EE+EK+ R+ + V + K E+ L+ QR +E+
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLR-----KEEEKLQEEEPQRQREL 271
Query: 400 EDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEEL-RKQEECLFFLKGTEGRERAFKQWL 458
++ + + +Q R +++ ++Q + R+ ++L RKQEE + E +E +Q
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE-----ERREQQEERREQQE 326
Query: 459 RRKRMEKMAEQQAVRE----RTRQLRLEAKRSKQLQ 490
RR++ E+ EQQ RE R +QLR E + ++ Q
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/165 (29%), Positives = 86/165 (52%), Gaps = 34/165 (20%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R+++L+++ EE+R + K E+ERR+ ++E++ D WL KRE+ E +R K
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRD-----WL--KREEETERHEQERRK 473
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEE--QMKERQTEELRKQEECLFFLKGTEGRERAFK 455
+ + E R + WLK + EE + +ER+ ++LR+++E E RE+ K
Sbjct: 474 QQLKRDQEEERRER-----WLKLEEEERREQQERREQQLRREQE--------ERREQRLK 520
Query: 456 QWLRRKRMEK--MAEQQAVRE----------RTRQLRLEAKRSKQ 488
+ +R+++ +EQQ RE R + RLE +R +Q
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
Score = 59.3 bits (142), Expect = 8e-09
Identities = 46/159 (28%), Positives = 85/159 (53%), Gaps = 25/159 (15%)
Query: 339 QKELQKQLEEKREKL-KREEERR--------KIEEEKEKKRENDIVFKAWLQKKREQVLE 389
+++L+++ EE+RE+L KREEE+R +++ E+E++R+ + KRE E
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL--------KRE---E 583
Query: 390 MRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEG 449
RR QR K ++ + ++ RL +++ E+++K + EE R+Q+ LK E
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQ 639
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
ER +Q LRR++ E+ ++ E +L KR +
Sbjct: 640 EERR-QQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Score = 59.3 bits (142), Expect = 8e-09
Identities = 99/535 (18%), Positives = 218/535 (40%), Gaps = 85/535 (15%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHT 62
+ +D + ++ + D E + E+ +A + ++E+ + ++ +E + + T
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 63 KRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQ----KDLEEE 118
R ++ L E + P+ + + F+E +L Q K LEEE
Sbjct: 1335 DRKFREEEQLLQEREEQ--------------PLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 119 E----DEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPL---EDTTT 171
+ E R+++ E+ Q + + ++ + R+RK + ++Q + + E+
Sbjct: 1381 QRLRRQERERKFLKEE--QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 172 FKNYFENERNMFGKLSQLCISND--FGQEDVLLSLTNGSCEENKDRTILVERDGKFELLN 229
+ E ER + QL F +E+ LL E + + ERD KF L
Sbjct: 1439 VRRQ-ERERKFLEEEQQLRQERHRKFREEEQLLQ------EREEQQLHRQERDRKF-LEE 1490
Query: 230 LQDIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLA 289
Q + Q +P++ ++ + + G+
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ-- 1548
Query: 290 YIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEK 349
+ +RK + +R + R + + R++E +++ E
Sbjct: 1549 --RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ------KVRRQEQERKFMED 1600
Query: 350 REKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVL--------------EMRRIQR 395
++L+R+E ++++ +E+++K D + LQ++ EQ L ++RR +R
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFRED---EQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKER----QTEELRKQEECLFFLKGTEGRE 451
+++ R+ R+ +Q + +++ Q ++R + ++LR+QE RE
Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE-----------RE 1706
Query: 452 RAF---KQWLRRKRME-KMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
R F +Q LRR+ +E K E++ +R+ T Q +L +R ++ + L + +P R
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQL--RRQERYRKILEEEQLRPER 1759
Score = 58.2 bits (139), Expect = 2e-08
Identities = 49/173 (28%), Positives = 91/173 (52%), Gaps = 13/173 (7%)
Query: 338 RQKELQKQLEEKREKLKREE-ERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRA 396
RQ K+L++K E+L EE E+R+ +E ++K RE + LQ++ EQ+L R +R
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE-----ELQQEEEQLLREEREKRR 1012
Query: 397 KEIEDMNSRENRDPQQAFRLWLKKKHEE---QMKERQ---TEELRKQEECLF-FLKGTEG 449
++ + R+ + QQ L+++ E+ Q +ERQ EEL+++EE L + T
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
R+ +Q+ + + +++ EQ E ++ R E +R + + L E + R
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Score = 57.4 bits (137), Expect = 3e-08
Identities = 50/171 (29%), Positives = 95/171 (55%), Gaps = 28/171 (16%)
Query: 338 RQKELQKQLEEKR--EKLKREEERRK---IEEEKEKKRENDIVFKAWLQK----KREQVL 388
R+++L+++ EE+R ++L+RE++ R+ + E++ +RE + + L++ +REQ L
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 389 ----EMRRIQRAKEIEDMNSRENRD-----PQQAFRLWLKKKHEEQMKERQTEELRKQEE 439
++RR Q + E + +E R+ Q+ R WLK++ E ER +E RKQ+
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE---TERHEQERRKQQ- 475
Query: 440 CLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQ 490
LK + ER ++WL+ + E+ EQQ RE+ + E +R ++L+
Sbjct: 476 ----LKRDQEEERR-ERWLKLEE-EERREQQERREQQLRREQEERREQRLK 520
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/165 (24%), Positives = 87/165 (52%), Gaps = 7/165 (4%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKE 398
Q+E ++ L E+REK + +E R+ EE+E ++E + + + +R Q LE R+ ++ +E
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE-RQYRKEEE 1085
Query: 399 IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWL 458
++ + R+ + +++ E + + R+ EEL+++EE L + + R + ++
Sbjct: 1086 LQQEEEQLLREEPEK-----RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 459 RRKRMEKMAEQQAVRER-TRQLRLEAKRSKQLQHHLYMSEAKPFR 502
R + + E+Q +RE ++ R E +R + + L E + R
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Score = 57.4 bits (137), Expect = 3e-08
Identities = 41/170 (24%), Positives = 88/170 (51%), Gaps = 14/170 (8%)
Query: 338 RQKELQKQLEEKREKLKREEE--RRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQR 395
RQ +++L+++ E+L EE RR+ E E++ ++E + LQ++ EQ+L +R
Sbjct: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE------LQQEEEQLLREEPEKR 1101
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKE------RQTEELRKQEECLFFLKGTEG 449
++ + RE + QQ L+++ E++ ++ R+ EE++++EE L + +
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
R + ++ R + + E+Q +RE + R E +R + + L + K
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Score = 57.4 bits (137), Expect = 3e-08
Identities = 34/144 (23%), Positives = 80/144 (55%), Gaps = 6/144 (4%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKE 398
Q+E ++ L E+ EK +R+E R+ EE+E ++E + + + +K+R Q LE R+ + +E
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE-RQYREEEE 1145
Query: 399 IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWL 458
++ + R+ + +++ E + + R+ EEL+++EE L + + R+ +Q+
Sbjct: 1146 VQQEEEQLLREEPEK-----RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 459 RRKRMEKMAEQQAVRERTRQLRLE 482
+ +++ +Q R+ ++ L+
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLK 1224
Score = 57.0 bits (136), Expect = 4e-08
Identities = 45/172 (26%), Positives = 91/172 (52%), Gaps = 16/172 (9%)
Query: 338 RQKELQKQLEEKREKLKRE-------EERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM 390
R++ L+++ EE+R+ LKRE +ERRK + +++++ E + +++R + E
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 391 RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMK---ERQTEELRKQEECLFFLKGT 447
R Q +E E+ + + ++ RL + + E+Q++ E + E+L K+EE K
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE----EKRL 558
Query: 448 EGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
E R +Q L+R++ E+ + E RQ RL+ ++ ++L+ L E +
Sbjct: 559 EQERR--EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Score = 57.0 bits (136), Expect = 4e-08
Identities = 99/515 (19%), Positives = 209/515 (40%), Gaps = 68/515 (13%)
Query: 1 MNENKDTDSKKSEEY----EDDFEKDLEWLINEN-EKSDASIIEMACEKEENINQDLKEN 55
+ E ++T ++ E E++ +++ E L+ E EK E C +EE + Q+ ++
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 56 ETVMEHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDL 115
+R + ++ ++E ++ + + + + E + +LE Q
Sbjct: 1124 LREEREKRRRQELERQYREEEEVQQEE----------EQLLREEPEKR-RRQELERQYRE 1172
Query: 116 EEE---EDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFK--DQLVDLE---VPPLE 167
EEE E+E++ R EK Q + +E +++RK +++ DQ DL+ P E
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 168 DTTTFKNYF--ENERNMFGKLSQLCISNDFGQEDVLLSL-TNGSCEENKDRTILVERDGK 224
+ + E F +L + + Q+D+ L + ++R +RD
Sbjct: 1233 NAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRH 1292
Query: 225 FELLNLQDIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSST 284
F P E + R S ++E + T
Sbjct: 1293 F--------------PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
Query: 285 GEPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQK---- 340
E + + R+ P DR + H+ Q R++
Sbjct: 1339 REEEQLLQE----REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK 1394
Query: 341 -ELQKQLEEKREKLKREEERRKIEEEKE-KKRENDIVFKAWLQKKREQVLEMRRIQRAKE 398
E Q + +E+ ++L+++ +R+ EEE++ ++E D +K RE+ ++RR +R ++
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD-------RKFREEEQQVRRQERERK 1447
Query: 399 IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWL 458
+ + ++ + FR + E+ ++ER+ ++L +QE FL+ + R +
Sbjct: 1448 FLEEEQQLRQERHRKFR-----EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD-- 1500
Query: 459 RRKRMEKMAEQQAVR---ERTRQLRLEAKRSKQLQ 490
R+ R +++ Q+ R E +QL + ++ K LQ
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
Score = 55.1 bits (131), Expect = 2e-07
Identities = 45/165 (27%), Positives = 93/165 (56%), Gaps = 25/165 (15%)
Query: 338 RQKELQKQLEEKR--EKLKREEERRKIEE----EKEKKRENDIVFKAWLQK----KREQV 387
R+++L+++ EE+R ++L+RE+E + E+ E++ +RE + + L++ +REQ
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 388 L----EMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFF 443
L ++RR Q+ + + + + + + +KHE++ +E++ + R+QEE +
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHE-------QKHEQERREQRLK--REQEERRDW 457
Query: 444 LKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
LK E ER ++ RRK+ K +++ RER +L E +R +Q
Sbjct: 458 LKREEETERHEQE--RRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/163 (26%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Query: 337 PRQKELQKQLEEKREKLKREEERRKIE--EEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
P Q+ QK+ E++RE + EE+ K E E+++++R ++ + W Q++ Q E RR +
Sbjct: 133 PGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDE---ELWRQRQEWQEREERRAE 189
Query: 395 -------RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGT 447
+ E E+ E ++ L K + E+Q + R+ ++ QEE
Sbjct: 190 EEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE-------- 241
Query: 448 EGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQ 490
E +E ++ + RK EK+ E++ R+R Q E R + Q
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/179 (25%), Positives = 92/179 (51%), Gaps = 15/179 (8%)
Query: 338 RQKELQKQLEEKRE-KLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRI--- 393
RQ++L+++ +E+RE +LKREEE ++E+ +++ E + + ++++EQ E +
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Query: 394 ----QRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEG 449
Q E + S+ P++ +++ EE+ + R++E ++EE + E
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 450 RERAFK-QWLRRKRMEKMAEQQAVR-----ERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
+ R F QW ++ E+ ++ + R +R RQLR E ++ ++ Q L E K R
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE-QRFLPEEEEKEQR 820
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/153 (26%), Positives = 87/153 (56%), Gaps = 16/153 (10%)
Query: 338 RQKELQKQLEEKREKLKREEER--RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQR 395
R++E ++QL R++ REEE+ ++ EE++ +++E D +K RE+ ++RR +R
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD-------RKFREEEQQLRRQER 1705
Query: 396 AKE-IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGR-ERA 453
++ +++ ++ ++ FR + E+ +E + E+LR+QE L+ + R ER
Sbjct: 1706 ERKFLQEEQQLRRQELERKFR-----EEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 454 FKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRS 486
+Q R++R K E++ +R+ + +L ++ S
Sbjct: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/152 (26%), Positives = 86/152 (56%), Gaps = 13/152 (8%)
Query: 339 QKELQKQLEEKREKLKREEERR--KIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRA 396
++E Q++ E++E+ +++EERR ++ E+E++RE Q +REQ E R Q
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQ--------QLRREQEEERREQQLR 365
Query: 397 KEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQ 456
+E E+ + +Q R + + E+Q+ R+ ++LR++++ + ++ +Q
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQ 423
Query: 457 WLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
LRR++ E+ EQ+ +ER R+ RL+ ++ ++
Sbjct: 424 QLRREQEEERHEQKHEQER-REQRLKREQEER 454
Score = 53.1 bits (126), Expect = 6e-07
Identities = 113/548 (20%), Positives = 209/548 (38%), Gaps = 89/548 (16%)
Query: 1 MNENKDTDSKKSEEYEDDFEKDLE------WLINENEKSDASIIEMACEKEENINQDLK- 53
+ ++T+ + E + ++D E WL E E+ E++E Q L+
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR--------EQQERREQQLRR 509
Query: 54 ENETVMEHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQK 113
E E E + + ++ LQ + + + E Q K E +K
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQ-------------LRREQEERREQLLKREEEK 556
Query: 114 DLEEEEDEEVRRYIMEKIVQANKLLQNQEPVND---KRERKLKFKDQLVDLEVPPLEDTT 170
LE+E E+ R E+ + ++LL+ +E KRE++ + + +L EV LE
Sbjct: 557 RLEQERREQ--RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Query: 171 TFKNYFENERNMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNL 230
+ + E + QL S + QE+ +E +++ + E + + L
Sbjct: 615 RREQRLKREEPEEERRQQLLKSEE--QEERRQQQLRREQQERREQRLKREEEEE----RL 668
Query: 231 QDIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKKEDSTA-----KIHAVTHSSTG 285
+ + E + +Q R + + +S A K+++ G
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 286 EPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKE---- 341
+ + R+ +R+ HR Q T+ +K
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERA-------HRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 342 ----LQKQLEEKREKLKREEERRKIE-----EEKEK--------KRENDIVFKAWLQKKR 384
+ L E+RE+ R EER++ E EE+EK +RE ++ F ++
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF----LEEE 837
Query: 385 EQVLEMRRIQRAKEIED--MNSRENRDPQQAFR--LWLKKKHEEQMKERQT--------E 432
EQ+ R Q+ +E ED +E R Q+ R W + EE+ + R T E
Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 433 ELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLE-AKRSKQLQH 491
+LRK+++ L + RE K+ + + + E+Q +E + LR E KR +Q +
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 492 HLYMSEAK 499
Y + K
Sbjct: 958 RQYRKDKK 965
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/185 (26%), Positives = 92/185 (49%), Gaps = 25/185 (13%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R++E Q + +E+ K +EE++ + +E + K RE + L+++ EQ R+ + K
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEE-----QLRQETEQEQLRRQERYRK 1748
Query: 398 EIEDMNSRENRDPQQAFRLWLKKK--HEEQMK-ERQTEELRKQEECLFFLKGTEGRERAF 454
+E+ R R+ QQ R +K EEQ++ ER+ ++LR QE F + + R+
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 455 KQWLRRKRME------------KMAEQQAVRERTRQLRLE-----AKRSKQLQHHLYMSE 497
+Q LR ++ + + EQ+ +ER RQ R E ++S++ + L+ E
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
Query: 498 AKPFR 502
+ R
Sbjct: 1869 EQKRR 1873
Score = 52.0 bits (123), Expect = 1e-06
Identities = 43/172 (25%), Positives = 87/172 (50%), Gaps = 14/172 (8%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R++E +Q EE+ + +RE+ RR+ E + +K++ LQ++ EQ+L R +R
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDE-------LQQEEEQLLREEREKRRL 1043
Query: 398 EIEDMNSRENRDPQQAFRLWL------KKKHEEQMKERQTEELRKQEECLFFLKGTEGRE 451
+ + RE + QQ L +++ E + + R+ EEL+++EE L + + R
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Query: 452 RAFKQWLRRKRMEKMAEQQAVR-ERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
+ ++ R + + E+Q +R ER ++ R E +R + + + E + R
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Score = 51.6 bits (122), Expect = 2e-06
Identities = 102/540 (18%), Positives = 213/540 (39%), Gaps = 90/540 (16%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHT 62
E ++ + ++ + E EK+L++L E + + E+E+ + +D + + +
Sbjct: 813 EEEEKEQRRRQRRER--EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS--QEQ 868
Query: 63 KRHSDPDKSLQDEVSPRRNDIISVPGIQPL-----DPISDSDSE----------NSFQES 107
+R L++E RR+ + + P +Q + + + E QE
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER 928
Query: 108 KLESQKDLEEEED-------EEVRRYIMEKIVQANKLLQNQEPV----------NDKRER 150
+ ++ L++EE+ E+ RR E+ + +K LQ +E +RE+
Sbjct: 929 QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
Query: 151 KLKFKDQLVDLEVPPLEDTTTFKNYFENERNMFGKLSQLCISNDFGQEDVLLSLTNGSCE 210
K + +++L E L + + E ER K ++ QE+ L
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKK-------DELQQEEEQL------LR 1035
Query: 211 ENKDRTILVERDGKF-ELLNLQDIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKK 269
E +++ L ER+ ++ E LQ Q E +Q L R ++
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLL------GEERETRRRQELERQYRKEEELQQE 1089
Query: 270 EDSTAKIHAVTHSSTGEPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPV 329
E+ + + L ++ + +R K + R
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEE--EQLLREEREKRRRQELERQYREE---- 1143
Query: 330 TSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKRE---- 385
Q+E ++ L E+ EK +R+E R+ EE+E ++E + + + +K+R+
Sbjct: 1144 ------EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 386 QVLEMRRIQRAKEIEDMNSRENR---------DPQQAFR---LWLKKKHEEQMKERQTEE 433
Q E +QR K + + R + + A R ++ K + EQ ++ + +
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 434 L--RKQEECLFFLKGTE---GRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
L R+ ++ L L G + RE+ ++W +R R E+Q RE ++ + ++S++
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR-HFPEEEQLEREEQKEAKRRDRKSQE 1316
Score = 51.2 bits (121), Expect = 2e-06
Identities = 41/177 (23%), Positives = 88/177 (49%), Gaps = 24/177 (13%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEE-----------EKEKKRENDIVF-KAWLQKKRE 385
+++E +QL+E+ + L+ ++ERR+ +E E+E+KR ++ K LQ++
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 386 QVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLK 445
+ E + +Q +E RE R Q+ R + + EEQ+++ + + LR++ E
Sbjct: 901 K--EQQLLQEEEEELQREEREKRRRQEQERQY---REEEQLQQEEEQLLREERE------ 949
Query: 446 GTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
R+ +Q+ + K++++ EQ E ++ R E ++ + + L E + R
Sbjct: 950 -KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005
Score = 51.2 bits (121), Expect = 2e-06
Identities = 97/538 (18%), Positives = 215/538 (39%), Gaps = 82/538 (15%)
Query: 1 MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQD----LKENE 56
+ +++D ++ E+ E+D ++ E + E+E+ + Q+ +E E
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467
Query: 57 TVMEHTK-----RHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLES 111
+++ + R K L++E RR + + F+E +L S
Sbjct: 1468 QLLQEREEQQLHRQERDRKFLEEEQQLRRQE-----------------RDRKFREQELRS 1510
Query: 112 Q---KDLEEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRE---RKLKFKDQLVD----- 160
Q + EEE + R+ K +Q + L+ QE +R+ RK + ++QL
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 161 ------------LEVPPLEDTTTFKNYFENERNMFGKLSQLCISND----FGQEDVLLSL 204
LE + + + E+E+ + + Q + + F +++ LL
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ- 1629
Query: 205 TNGSCEENKDRTILVERDGKFELLNLQDIASQGFLPPINNANSTENDPQQLLPRSSNSSV 264
E + + ERD KF Q + ++ + + +QLL +
Sbjct: 1630 -----EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 265 SGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSA 324
+++ + E + L R+ ++ + + +
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744
Query: 325 HISPVTSTYCLSPRQKELQKQLEEKREKLKREEE-RRKIEEEKEKKRENDIVFKAWLQKK 383
+ L P ++E Q + +E+ K + EE+ R++ EE++ + +E+D F+ Q +
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
Query: 384 REQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFF 443
+E+ + R Q+ R+ + + +L L+++ E+++++ + + R +E+
Sbjct: 1805 QEREEQQLRPQQ---------RDGKYRWEEEQLQLEEQ-EQRLRQERDRQYRAEEQF--- 1851
Query: 444 LKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLE--AKRSKQLQHHLYMSEAK 499
T+ + R +Q L ++ EQ+ +ER R+LR E ++ K+ Q H + E K
Sbjct: 1852 --ATQEKSRREEQELWQEE-----EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 24/183 (13%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEE-----KEKKRENDIVFKA-----WLQKKREQVL 388
Q+E ++ L E++EK ++E ER+ EEE K K+R D ++ W +K V
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Query: 389 EM------RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLF 442
+ R ++ +++ED R+ + Q L E+Q ++R+ E R Q+
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL----GEQQERDREQERRRWQQRDRH 1292
Query: 443 FLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHH---LYMSEAK 499
F + E ER ++ +R+ + E+Q +RE + R + ++ + L E +
Sbjct: 1293 FPE-EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Query: 500 PFR 502
P R
Sbjct: 1352 PLR 1354
Score = 42.7 bits (99), Expect = 8e-04
Identities = 86/468 (18%), Positives = 181/468 (38%), Gaps = 77/468 (16%)
Query: 5 KDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHTK- 63
++ D K EE + ++ + E E E+E+ +++ ++ + + E +
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 64 --------RHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDL 115
R D D+ ++E R+ + +S + + F +LE QK
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQE--------REEQQLSRQERDRKF---RLEEQKVR 1589
Query: 116 EEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLV-DLEVPPLEDTTTFKN 174
+E++ R ME Q + + Q+ + +R+RK + +QL+ + E L +
Sbjct: 1590 RQEQE----RKFMEDEQQLRRQ-EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 175 YFENERNMFGKLSQLCISND----FGQEDVLLSLTNGSCEENKDRTILVERDGKF----E 226
+ E E + + + + +D F +E+ LL E + + ERD KF +
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ------EGEEQQLRRQERDRKFREEEQ 1698
Query: 227 LLNLQDIASQGFLPPINNANSTE-----NDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTH 281
L Q+ + FL E + +QL + + ++++ KI
Sbjct: 1699 QLRRQE-RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL---RRQERYRKILEEEQ 1754
Query: 282 SSTGEPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRT----QSAHISPVTSTYCLSP 337
+ + +RK + +R + +S + + L P
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRP 1814
Query: 338 RQK-------ELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM 390
+Q+ E Q QLEE+ ++L++E +R+ EE+ +E ++ EQ L
Sbjct: 1815 QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK--------SRREEQELWQ 1866
Query: 391 RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQE 438
Q+ ++ + RE ++++ +E+ + RQ E++ QE
Sbjct: 1867 EEEQKRRQERERKLREEH---------IRRQQKEEQRHRQVGEIKSQE 1905
Score = 42.4 bits (98), Expect = 0.001
Identities = 40/177 (22%), Positives = 91/177 (51%), Gaps = 21/177 (11%)
Query: 342 LQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIED 401
L+++ EEKR + + + + R+ E+ +++ E + + +K RE+ E+R ++ ++ +
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE--ELRHQEQGRKFLE 1378
Query: 402 MNSRENRDPQQAFRLWLK-------KKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
R R Q+ R +LK ++ E+Q+++ + + R++E+ L + R+R F
Sbjct: 1379 EEQRLRR--QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL----SRQERDRKF 1432
Query: 455 K---QWLRRKRMEKM---AEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFRFTD 505
+ Q +RR+ E+ EQQ +ER R+ R E + ++ + + + +F +
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Score = 32.3 bits (72), Expect = 1.0
Identities = 20/88 (22%), Positives = 43/88 (48%)
Query: 393 IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
+Q ++ ED E RD Q +++ + Q +ER+ E +Q E L+ + + R
Sbjct: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRR 169
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLR 480
+ W +R+ ++ E++A E+ + +
Sbjct: 170 DEELWRQRQEWQEREERRAEEEQLQSCK 197
Score = 32.3 bits (72), Expect = 1.0
Identities = 25/141 (17%), Positives = 61/141 (43%), Gaps = 12/141 (8%)
Query: 11 KSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHTKRHSDPDK 70
++EE+ D+ + L+ K + E+++ + Q+ +E E T + +K
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 71 SLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEEVRRYIMEK 130
LQ+E R+ ++ + + + +L ++ EE++ + +RR +
Sbjct: 260 -LQEEEPQRQRELQE-----------EEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 131 IVQANKLLQNQEPVNDKRERK 151
Q + + QE +++ER+
Sbjct: 308 RKQEEERREQQEERREQQERR 328
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 63.9 bits (154), Expect = 3e-10
Identities = 49/162 (30%), Positives = 94/162 (58%), Gaps = 21/162 (12%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKR--EQVLEMRRIQRA- 396
+E +K++ ++ EK+ R+EER + +E K +++E K W Q+KR EQ E+R ++
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEE----KMWRQEKRLREQEKELREQEKEL 337
Query: 397 KEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLF---------FLKGT 447
+E +++ +E + +Q ++W + EE+M+E Q E++ +QEE L+ K
Sbjct: 338 REQKELREQEEQMQEQEEKMW---EQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 448 EGRERAFKQWLR-RKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ ER ++Q R R++ E+M EQ+ + E+ ++R E K +Q
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQ 435
Score = 60.8 bits (146), Expect = 3e-09
Identities = 46/166 (27%), Positives = 94/166 (56%), Gaps = 14/166 (8%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM-RRI 393
L ++KEL++Q +E RE+ + E+ +++E++EK E + +K REQ +M R+
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE-------EKMREQEEKMWRQE 375
Query: 394 QRAKEIE-DMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL-KGTEGRE 451
+R E E M +E + Q R+W + +E+++E++ E +R+QE+ + K E ++
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERMW---EQDERLREKE-ERMREQEKMWEQVEKMREEKK 431
Query: 452 RAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSE 497
++ R + EKM E++ +RER +++R E + ++ + + E
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 477
Score = 60.8 bits (146), Expect = 3e-09
Identities = 40/171 (23%), Positives = 96/171 (56%), Gaps = 13/171 (7%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R +E +K++ E+ E ++ +EE+ + +EEK +++E K W Q+++ Q E + ++ +
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE----KMWEQEEKMQEQEEKMWEQEE 645
Query: 398 EIEDMNSR---ENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL-----KGTEG 449
++ + + + R P+Q +LW +K +EQ K ++ EE ++E + K T
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 450 RERAFKQWLRRKRMEKM-AEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+E+ ++ R+R +KM E++ +RE+ +++ + ++ ++ + ++ E K
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Score = 60.5 bits (145), Expect = 4e-09
Identities = 49/205 (23%), Positives = 98/205 (47%), Gaps = 46/205 (22%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK- 397
Q+++ +Q+E+ RE+ K +E+ +K +++EK +E + + + +KK + E R Q K
Sbjct: 416 QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER--EKKMREEEETMREQEEKM 473
Query: 398 --------EIEDMNSRENRDPQQAFRLWLKKKHEEQMKE--RQTEELRKQEECL------ 441
E E+ ++ R P+Q +LW ++K +EQ ++ Q E++R QEE
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 442 ------------FFLKGTEGRERAFKQWLRRKRM---------------EKMAEQQAVRE 474
+ + + R++ K W + +RM EKM E++ +RE
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE 593
Query: 475 RTRQLRLEAKRSKQLQHHLYMSEAK 499
R +++R E + ++ + + E K
Sbjct: 594 REKKMREEEEMMREQEEKMQEQEEK 618
Score = 55.8 bits (133), Expect = 9e-08
Identities = 46/173 (26%), Positives = 84/173 (48%), Gaps = 27/173 (15%)
Query: 337 PRQKELQKQLEEKREKLKREEERRKI-EEEKEKKRENDIVFKAWLQKKREQVLEMRRIQR 395
P QKE + E+ +E+ K +E+ KI E+EK +K+ + K W Q+K + MR ++
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFK 455
E+ RE + Q + EE+M+E Q EE+ +QEE ++ E+ K
Sbjct: 721 KMREEEEMMREQEEKMQ--------EQEEKMQE-QEEEMWEQEEKMW--------EQEEK 763
Query: 456 QWLRRK---------RMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
W +++ EKM EQ+ + E+ ++R + ++ + + + E K
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Score = 55.1 bits (131), Expect = 2e-07
Identities = 39/181 (21%), Positives = 93/181 (51%), Gaps = 20/181 (11%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+++ ++K+ +E+ +K +EE+ + EEE+ ++RE + + + +++E+ ++ + + +
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 398 EIEDMNSRENRDPQQAFRLW---------LKKKHEEQMKERQTEELRKQEECLFFLKGTE 448
+ E M +E + +Q ++W +K E+Q Q E+L + E+ K E
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 449 GRERAFKQWLRRKR----------MEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEA 498
E+ ++Q K+ EKM E++++RER +++R E + ++ + + E
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 499 K 499
K
Sbjct: 742 K 742
Score = 53.9 bits (128), Expect = 3e-07
Identities = 45/157 (28%), Positives = 82/157 (52%), Gaps = 24/157 (15%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQ--KKREQVLEMRRIQR 395
+ +E + Q+ E+ EK++ +E++ +EE+ +K+ + K W Q K RE+ R ++
Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFK 455
+E E+M RE + Q + EE+M+E Q E++ +QEE + +E+ K
Sbjct: 598 MREEEEM-MREQEEKMQ--------EQEEKMQE-QEEKMWEQEEKM--------QEQEEK 639
Query: 456 QWLRRKRM----EKMAEQQAVRERTRQLRLEAKRSKQ 488
W + ++M EKM EQQ + E+ +L K +Q
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Score = 53.1 bits (126), Expect = 6e-07
Identities = 46/171 (26%), Positives = 90/171 (52%), Gaps = 24/171 (14%)
Query: 341 ELQKQLEEKREKLKREEER------RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
E +KQ+ E+ +K++ +EER R E+E E+ RE + K W EQV +MR +
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQE---KMW-----EQVEKMREEK 430
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKK---HEEQMKERQTEELRKQEECLFFLKGTEGRE 451
+ +E E + Q+ R+ ++K EE+ Q E+++KQEE ++ E E
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW-----EQEE 485
Query: 452 RAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
+ ++Q ++ EK+ EQ+ ++E+ ++ + ++ + Q ++ E K +R
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWR 535
Score = 52.8 bits (125), Expect = 7e-07
Identities = 45/170 (26%), Positives = 94/170 (55%), Gaps = 17/170 (10%)
Query: 339 QKELQKQ-LEEKREKL----KREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRI 393
+KE Q+Q L E++EKL K +E+ KI E++EK R+ + + W Q+K+ M R
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE---EMWGQEKK-----MWRQ 536
Query: 394 QRAKEIED-MNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
++ +E ED M +E + Q ++W +++ E+ + Q ++ QEE + + RE+
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596
Query: 453 AFK--QWLRRKRMEKMAEQ-QAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+ + + R++ EKM EQ + ++E+ ++ + ++ ++ + ++ E K
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646
Score = 50.8 bits (120), Expect = 3e-06
Identities = 43/151 (28%), Positives = 78/151 (51%), Gaps = 26/151 (17%)
Query: 343 QKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKK-REQVLEMRRIQRAKEIED 401
Q++L E++EKL E+ + E+EK +++E I + ++KK +EQ + ++ +E E
Sbjct: 657 QQRLPEQKEKLWEHEKMQ--EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 402 MNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRK 461
M RE K + EE+M Q E++++QEE + +E+ + W + +
Sbjct: 715 MREREK-----------KMREEEEMMREQEEKMQEQEEKM--------QEQEEEMWEQEE 755
Query: 462 RM----EKMAEQQAVRERTRQLRLEAKRSKQ 488
+M EKM EQQ + E+ +L K +Q
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 786
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/160 (26%), Positives = 84/160 (52%), Gaps = 14/160 (8%)
Query: 343 QKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKR--EQVLEMRRIQRAKEIE 400
Q Q +E++ R+EE + +E+K +K+E K W Q++R EQ +MR ++ E
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEE----KMWRQEERLREQEGKMR-----EQEE 314
Query: 401 DMNSRENRDPQQAFRLWLKKKHEEQMKE-RQTEELRKQEECLFFLKGTEGRERAFKQWLR 459
M +E R +Q L ++K + KE R+ EE +++E + + + RE+ K W +
Sbjct: 315 KMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 374
Query: 460 RKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+R+ + +Q +RE+ +++R + +R + L E +
Sbjct: 375 EERLWEQEKQ--MREQEQKMRDQEERMWEQDERLREKEER 412
Score = 47.8 bits (112), Expect = 2e-05
Identities = 46/194 (23%), Positives = 95/194 (48%), Gaps = 34/194 (17%)
Query: 335 LSPRQKELQKQLEE---KREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM- 390
+S R K+ + +EE +R+ L E R I E+ KK+ ++ K L + + +++
Sbjct: 188 VSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLN 247
Query: 391 -----RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFF-- 443
R+++RAK + + +W + EE+++E Q +++RKQEE ++
Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEE----MW---RQEEELRE-QEKKIRKQEEKMWRQE 299
Query: 444 --LKGTEG--RERAFKQWLRRKRM-----------EKMAEQQAVRERTRQLRLEAKRSKQ 488
L+ EG RE+ K W + KR+ +++ EQ+ +RE+ Q++ + ++ +
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 489 LQHHLYMSEAKPFR 502
+ + E K +R
Sbjct: 360 QEEKMREQEEKMWR 373
Score = 46.6 bits (109), Expect = 5e-05
Identities = 34/122 (27%), Positives = 69/122 (56%), Gaps = 8/122 (6%)
Query: 343 QKQLEEKREKL---KREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK-- 397
Q++L E++EKL ++ +E+ KI E++EK R+ + + +K R Q +MR +
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQW 457
+ E M +E + Q ++W +++ E+ + Q E++R+QEE ++G E + R ++
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE---KMRGQEEKMREQEEK 883
Query: 458 LR 459
+R
Sbjct: 884 MR 885
Score = 46.2 bits (108), Expect = 7e-05
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 30/159 (18%)
Query: 338 RQKELQKQLEEK--------------------REKLKREEERR----KIEEEKEKKREND 373
+++E ++ EEK +EK++ EE R K+ EE+E RE +
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 374 IVFKAWLQKKREQVLEM-RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMK-ERQT 431
+ +K +EQ EM + ++ E E+ + R P+Q +LW +K +EQ K Q
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 432 EELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQ 470
E++R QEE ++G E + R ++ +R + EKM Q+
Sbjct: 794 EKMRDQEE---KMRGQEEKMRGQEEKMRGQE-EKMWGQE 828
Score = 32.7 bits (73), Expect = 0.80
Identities = 28/150 (18%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 10 KKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLK--ENETVMEHTKRHSD 67
+K +E E+ ++ E + + EK +M ++E+ Q+ K E + + E ++ +
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Query: 68 PDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEE-----EEDEE 122
+K + E + + I + ++ + + ++ + K+ ++ + E E+EE
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQ--EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 123 VRRYIMEKIVQANKLLQNQEPVNDKRERKL 152
+ R EK+ + + +Q QE ++E K+
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQEEKM 757
Score = 31.6 bits (70), Expect = 1.8
Identities = 29/162 (17%), Positives = 77/162 (47%), Gaps = 9/162 (5%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENI--NQDLKENETVME 60
E +K +E E++ + E + + EK + E++E + ++ ++E E + E
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ--QRLPEQKEKLWEHEKMQEQEKIWE 791
Query: 61 HTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDL---EE 117
++ D ++ ++ + R + G + + + + + QE K+ Q++ +E
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQE--EKMWGQEEKMWGQEEKMWGQEEKMWGQE 849
Query: 118 EEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLV 159
E+ EE + EK+ + + ++ QE ++E K++ +++ +
Sbjct: 850 EKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 29.6 bits (65), Expect = 6.8
Identities = 30/161 (18%), Positives = 67/161 (41%), Gaps = 24/161 (14%)
Query: 5 KDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQD---LKENETVMEH 61
++ + K + E +E++ + E + D E E++E + + ++E E + E
Sbjct: 365 REQEEKMWRQEERLWEQEKQMREQEQKMRDQE--ERMWEQDERLREKEERMREQEKMWEQ 422
Query: 62 TKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDE 121
++ + K + E R D E QE + +++ + E+E
Sbjct: 423 VEKMREEKKMQEQEKKTR-------------------DQEEKMQEEERIREREKKMREEE 463
Query: 122 EVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLE 162
E R EK+ + + + QE +++R + K++L + E
Sbjct: 464 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 504
Score = 29.6 bits (65), Expect = 6.8
Identities = 14/59 (23%), Positives = 33/59 (55%)
Query: 99 DSENSFQESKLESQKDLEEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQ 157
D E +E + +++ + E+EE+ R EK+ + + +Q QE ++E K++ +++
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 63.2 bits (152), Expect = 6e-10
Identities = 39/168 (23%), Positives = 89/168 (52%), Gaps = 7/168 (4%)
Query: 301 CPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERR 360
C S+ V S+ ++ K R + ++P + +++ + QL+ E ++ E+R+
Sbjct: 118 CASTQVESENNQEEQKQV-RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRK 176
Query: 361 KIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRE------NRDPQQAF 414
++EE +++K + K W+QKK EQ + R + KE+E+ ++E ++ +
Sbjct: 177 EMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKY 236
Query: 415 RLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKR 462
+ WLKKK+ E+ + ++ E+ +++++ + E E+ F++WL +
Sbjct: 237 QEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
Score = 49.3 bits (116), Expect = 8e-06
Identities = 36/164 (21%), Positives = 90/164 (54%), Gaps = 11/164 (6%)
Query: 336 SPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRI-- 393
S R ELQ + E +EE++++ + + ++ F +++R++ L+++ +
Sbjct: 109 SLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDR-LQLKALEE 167
Query: 394 --QRAKEIEDMNSRENRD--PQQAFRLWLKKKHEEQMKERQTEELRKQEE-CLFFLKGTE 448
Q+ ++ ++M RE R ++ + W++KK+E++ KER+ + ++ EE L+
Sbjct: 168 LNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEY 227
Query: 449 GRERA---FKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQL 489
+E+A +++WL++K E+ ++ +E+ +Q + E + K++
Sbjct: 228 LQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEI 271
Score = 36.2 bits (82), Expect = 0.072
Identities = 45/221 (20%), Positives = 94/221 (42%), Gaps = 27/221 (12%)
Query: 295 PLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLK 354
P +R + S +V ++G G R+ S P C + + L + +
Sbjct: 24 PRSRPSSDSCSVPMTGARGQGLEVVRSPS----PPLPLSCSNSTRSLLSPL---GHQSFQ 76
Query: 355 REEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ--RAKEIEDMNSRENRD--- 409
+E+ E+E++ E D+ A + + L +Q + ++E N++E +
Sbjct: 77 FDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVR 136
Query: 410 -------PQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGR----ERAFKQWL 458
P + + + +K+ ++++ + EEL +Q E ++ E R E K+W+
Sbjct: 137 LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWV 196
Query: 459 RRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
++K +K E RE+ +E K +K+L+ +AK
Sbjct: 197 QKKNEQKRKE----REQKINKEMEEKAAKELEKEYLQEKAK 233
Score = 29.6 bits (65), Expect = 6.8
Identities = 18/83 (21%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 310 RSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEK------REKLKREEERRKIE 363
R + K N + + Y +++ Q+ L++K R+K ++E+E+++
Sbjct: 204 RKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQA 263
Query: 364 EEKEKKRENDIVFKAWLQKKREQ 386
E +EKK + F+ WL+ + +
Sbjct: 264 EIQEKKEIAEKKFQEWLENAKHK 286
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 62.0 bits (149), Expect = 1e-09
Identities = 47/159 (29%), Positives = 81/159 (50%), Gaps = 25/159 (15%)
Query: 345 QLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNS 404
Q E +R+K +RE E+RK E EKE+KRE K +KKRE+ E R ++ +E +
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKK-KRKKRERGKERERKRKEREKQRKER 89
Query: 405 REN-----------RDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERA 453
RE R+ +Q R KKK E + +ER+ ++ R+ R+R
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE-------------RKRK 136
Query: 454 FKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHH 492
++ +R++ K +++ RER R+ R + +R K+ + +
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175
Score = 61.2 bits (147), Expect = 2e-09
Identities = 44/155 (28%), Positives = 85/155 (54%), Gaps = 8/155 (5%)
Query: 338 RQKELQKQLEEKREKLKR--EEERRKIEEEKEKK--RENDIVFKAWLQKKREQVLEMRRI 393
R++E K+ ++KR+K +R E ER++ E EK++K RE + + +KKRE+ RR
Sbjct: 54 RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRE 113
Query: 394 QRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERA 453
++ K+ REN+ ++ R +KK + ++R+ E +++ + K + ER
Sbjct: 114 RKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK----RKKRKKEERE 169
Query: 454 FKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
K+ RK +K E++ RER ++ + E ++ K+
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKE 204
Score = 58.9 bits (141), Expect = 1e-08
Identities = 40/157 (25%), Positives = 83/157 (52%), Gaps = 9/157 (5%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+++E +++ EK+ K +RE+ERRK ++EK KKRE + +KK+E+ R ++ +
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEK-KKRERKQRGRRERKKKKERKERERENKQRR 131
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQW 457
E + R+ + ++ R + K E + K+R+ EE K+ E R+ K+
Sbjct: 132 ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRE--------RNRKERKKER 183
Query: 458 LRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLY 494
R++R E+ E++ R + ++ + + K +Q ++
Sbjct: 184 ERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVF 220
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 62.0 bits (149), Expect = 1e-09
Identities = 44/166 (26%), Positives = 88/166 (53%), Gaps = 32/166 (19%)
Query: 338 RQKELQKQLEEKREKLKREEERRKI---EEEKEKKRENDIVFKAWLQKKREQVLE-MRRI 393
++K K++EE + K+EEE R++ ++E+E++R ++ LQKK+E+ E +R+
Sbjct: 624 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL-----LQKKKEEEQERLRKA 678
Query: 394 QRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERA 453
AK + + +E R+ + +++ E + +ER+ +E R+Q ER
Sbjct: 679 AEAKRLAEQREQERREQE-------RREQERREQERREQERREQ-------------ERQ 718
Query: 454 FKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+ RR+ E++ ++ ++ER + LRL+ +QLQ L + K
Sbjct: 719 LAEQERRREQERLQAERELQEREKALRLQ---KEQLQRELEEKKKK 761
Score = 57.8 bits (138), Expect = 2e-08
Identities = 51/177 (28%), Positives = 86/177 (48%), Gaps = 28/177 (15%)
Query: 339 QKELQKQLEEKRE-----KLKREEERRK-------IEEEKEKKRENDIVFKAWLQKKREQ 386
Q QK E+KR KLKREE RK +E+ KE+K++ A + +K E+
Sbjct: 553 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEK 612
Query: 387 VLEMRRIQR-------AKEIEDMNSRENRDPQQAFRLWLKKKHEE--------QMKERQT 431
E R + AK++E++ +R ++ + WL+++ EE + KE +
Sbjct: 613 AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ 672
Query: 432 EELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
E LRK E + E +ER ++ ++R E+ +Q RE+ RQL + +R +Q
Sbjct: 673 ERLRKAAEAKRLAEQRE-QERREQERREQERREQERREQERREQERQLAEQERRREQ 728
Score = 49.7 bits (117), Expect = 6e-06
Identities = 43/171 (25%), Positives = 88/171 (51%), Gaps = 22/171 (12%)
Query: 335 LSPRQKELQKQLEEKREKLKREEE-----RRKIEEEKEKKRENDIVFKAWLQKKREQVLE 389
+ P+ ++K+ ++ E L+R+EE R+K+EE+K ++ E ++ KRE+
Sbjct: 528 MDPKCSFVEKE-RQRLENLRRKEEAEQLRRQKVEEDKRRRLEE-------VKLKREE--R 577
Query: 390 MRRIQRAKE-IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTE 448
+R++ +A+E +E M + + +Q F + +K E+ +ER EE K++ ++ E
Sbjct: 578 LRKVLQARERVEQMKEEKKKQIEQKFAQ-IDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636
Query: 449 GRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
R + ++ R + + QQ ER Q L+ K+ ++ + +EAK
Sbjct: 637 ARRKQEEEARRLRWL-----QQEEEERRHQELLQKKKEEEQERLRKAAEAK 682
Score = 49.7 bits (117), Expect = 6e-06
Identities = 47/156 (30%), Positives = 79/156 (50%), Gaps = 15/156 (9%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKE 398
++E +KQ+E+K ++ + E+ K E E+K + K KK E+V E RR Q +
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK-----KKAAAKKMEEV-EARRKQEEEA 645
Query: 399 IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEEL------RKQEECLFFLKGTEGRER 452
++ + ++ L KKK EEQ + R+ E R+QE + E RE+
Sbjct: 646 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 705
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
++ RR++ ++AEQ+ RE Q RL+A+R Q
Sbjct: 706 ERREQERREQERQLAEQERRRE---QERLQAERELQ 738
Score = 48.9 bits (115), Expect = 1e-05
Identities = 46/161 (28%), Positives = 82/161 (50%), Gaps = 16/161 (9%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKR--EQVLEMRRIQR 395
R+KE +QL +R+K++ E++RR++EE K K+ E + LQ + EQ+ E ++ Q
Sbjct: 546 RRKEEAEQL--RRQKVE-EDKRRRLEEVKLKREER---LRKVLQARERVEQMKEEKKKQI 599
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLK--GTEGRERA 453
++ ++ + + ++ KK K + E RKQEE L+ E ER
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
Query: 454 FKQWLRRK------RMEKMAEQQAVRERTRQLRLEAKRSKQ 488
++ L++K R+ K AE + + E+ Q R E +R +Q
Sbjct: 660 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 700
Score = 48.1 bits (113), Expect = 2e-05
Identities = 40/157 (25%), Positives = 84/157 (53%), Gaps = 33/157 (21%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEK------KRENDIVFKAWLQKKREQVLEMRR 392
Q+ LQK+ EE++E+L++ E +++ E++E+ +RE Q++REQ E R
Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE---------QERREQ--ERRE 709
Query: 393 IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
+R ++ + +E R Q+ + + E +++ER+ + LR Q+E L +R
Sbjct: 710 QERREQERQLAEQERRREQE------RLQAERELQERE-KALRLQKEQL---------QR 753
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQL 489
++ +++ +++AE+Q E+ ++ + A SK L
Sbjct: 754 ELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 790
Score = 29.3 bits (64), Expect = 8.8
Identities = 13/36 (36%), Positives = 29/36 (80%), Gaps = 2/36 (5%)
Query: 338 RQKELQKQLEEKREKLKREE--ERRKIEEEKEKKRE 371
++++LQ++LEEK++K +++ ER+ EE+++K +E
Sbjct: 747 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 62.0 bits (149), Expect = 1e-09
Identities = 44/166 (26%), Positives = 88/166 (53%), Gaps = 32/166 (19%)
Query: 338 RQKELQKQLEEKREKLKREEERRKI---EEEKEKKRENDIVFKAWLQKKREQVLE-MRRI 393
++K K++EE + K+EEE R++ ++E+E++R ++ LQKK+E+ E +R+
Sbjct: 620 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL-----LQKKKEEEQERLRKA 674
Query: 394 QRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERA 453
AK + + +E R+ + +++ E + +ER+ +E R+Q ER
Sbjct: 675 AEAKRLAEQREQERREQE-------RREQERREQERREQERREQ-------------ERQ 714
Query: 454 FKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+ RR+ E++ ++ ++ER + LRL+ +QLQ L + K
Sbjct: 715 LAEQERRREQERLQAERELQEREKALRLQ---KEQLQRELEEKKKK 757
Score = 56.2 bits (134), Expect = 7e-08
Identities = 45/166 (27%), Positives = 83/166 (50%), Gaps = 20/166 (12%)
Query: 339 QKELQKQLEEKRE-----KLKREEERRKI-------EEEKEKKRENDIVFKAWLQKKREQ 386
Q QK E+KR KLKREE RK+ E+ KE+K++ A + +K E+
Sbjct: 549 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEK 608
Query: 387 VLEMRRIQR-------AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEE 439
E R + AK++E++ +R ++ + WL+++ EE+ + ++ + +K+EE
Sbjct: 609 AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER-RHQELLQKKKEEE 667
Query: 440 CLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
K E + A ++ R+ E+ +++ +ER Q R E +R
Sbjct: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713
Score = 53.5 bits (127), Expect = 4e-07
Identities = 46/167 (27%), Positives = 87/167 (52%), Gaps = 18/167 (10%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERR-KIEEEKEKKRENDIVFKAWLQKKREQVLEMRRI 393
+ P++KE Q+ LE R K + E+ RR K+EE+K ++ E ++ KRE+ +R++
Sbjct: 528 MDPKEKERQR-LENLRRKEEAEQLRRQKVEEDKRRRLEE-------VKLKREE--RLRKV 577
Query: 394 QRAKE-IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
+A+E +E M + + +Q F + +K E+ +ER EE K++ ++ E R +
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQ-IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRK 636
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
++ R + + QQ ER Q L+ K+ ++ + +EAK
Sbjct: 637 QEEEARRLRWL-----QQEEEERRHQELLQKKKEEEQERLRKAAEAK 678
Score = 52.0 bits (123), Expect = 1e-06
Identities = 40/159 (25%), Positives = 87/159 (54%), Gaps = 12/159 (7%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R++ L+K L+ RE++++ +E +K + E++ + ++ KA ++ E+ + ++ AK
Sbjct: 570 REERLRKVLQA-RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE--KAKKKAAAK 626
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEE--------QMKERQTEELRKQEECLFFLKGTEG 449
++E++ +R ++ + WL+++ EE + KE + E LRK E + E
Sbjct: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE- 685
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ER ++ ++R E+ +Q RE+ RQL + +R +Q
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQ 724
Score = 49.7 bits (117), Expect = 6e-06
Identities = 47/156 (30%), Positives = 79/156 (50%), Gaps = 15/156 (9%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKE 398
++E +KQ+E+K ++ + E+ K E E+K + K KK E+V E RR Q +
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK-----KKAAAKKMEEV-EARRKQEEEA 641
Query: 399 IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEEL------RKQEECLFFLKGTEGRER 452
++ + ++ L KKK EEQ + R+ E R+QE + E RE+
Sbjct: 642 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 701
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
++ RR++ ++AEQ+ RE Q RL+A+R Q
Sbjct: 702 ERREQERREQERQLAEQERRRE---QERLQAERELQ 734
Score = 48.1 bits (113), Expect = 2e-05
Identities = 40/157 (25%), Positives = 84/157 (53%), Gaps = 33/157 (21%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEK------KRENDIVFKAWLQKKREQVLEMRR 392
Q+ LQK+ EE++E+L++ E +++ E++E+ +RE Q++REQ E R
Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE---------QERREQ--ERRE 705
Query: 393 IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
+R ++ + +E R Q+ + + E +++ER+ + LR Q+E L +R
Sbjct: 706 QERREQERQLAEQERRREQE------RLQAERELQERE-KALRLQKEQL---------QR 749
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQL 489
++ +++ +++AE+Q E+ ++ + A SK L
Sbjct: 750 ELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786
Score = 40.0 bits (92), Expect = 0.005
Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 10/151 (6%)
Query: 353 LKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQ 412
+KR R +EKE++R ++ K ++ R Q +E + +R +E++ R Q
Sbjct: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
Query: 413 AFRLWLKKKHEEQMKERQTEELRKQ----EECLFFLKGTEGRERAFKQWLRRKRMEKMAE 468
A ++ EQMKE + +++ ++ +E K E K+ K+ME++
Sbjct: 580 A------RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA 633
Query: 469 QQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
++ E R+LR + ++ +H + + K
Sbjct: 634 RRKQEEEARRLRWLQQEEEERRHQELLQKKK 664
Score = 33.5 bits (75), Expect = 0.47
Identities = 47/218 (21%), Positives = 86/218 (39%), Gaps = 26/218 (11%)
Query: 293 QPPLNRKTCPSSAVNSDRSKGNGKSNHR-TQSAHISPVTSTYCLSP------RQKELQKQ 345
+PP + ++ + GN H T+ A+ +P SP +Q+ Q
Sbjct: 377 EPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQ 436
Query: 346 LEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQ-----------VLEMRRIQ 394
+ RE + +R ++ + E + LQ R + V +R
Sbjct: 437 ADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFL 496
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQM----KERQT-EELRKQEEC--LFFLKGT 447
+ M P+ + ++K+ +M KERQ E LR++EE L K
Sbjct: 497 HTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVE 556
Query: 448 EGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
E + R ++ ++ KR E++ + RER Q++ E K+
Sbjct: 557 EDKRRRLEE-VKLKREERLRKVLQARERVEQMKEEKKK 593
Score = 29.3 bits (64), Expect = 8.8
Identities = 13/36 (36%), Positives = 29/36 (80%), Gaps = 2/36 (5%)
Query: 338 RQKELQKQLEEKREKLKREE--ERRKIEEEKEKKRE 371
++++LQ++LEEK++K +++ ER+ EE+++K +E
Sbjct: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 60.8 bits (146), Expect = 3e-09
Identities = 47/175 (26%), Positives = 100/175 (57%), Gaps = 22/175 (12%)
Query: 338 RQKELQKQLEE--KREKLKREEERRKIEE---EKEKKRENDIVFKAWLQKKREQVLEMRR 392
++K++ +Q E+ ++EK++ EE+R++ EE ++EK RE + + W QK++ E R
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE---EIWRQKEKMHEQEKIR 491
Query: 393 IQRAK---EIEDMNSRENRDPQQAFRLWLK----KKHEEQMKERQTEELRKQEECLFFLK 445
Q K + E M+ +E + +Q ++W + ++ EE+++E Q E++R+QEE +
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE-QEEKIREQEEMM---- 546
Query: 446 GTEGRERAFKQWLRRKRMEKMAEQ-QAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
E E+ +Q + + EKM Q + +RE+ ++R + ++ ++ + ++ E K
Sbjct: 547 -QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/164 (24%), Positives = 87/164 (53%), Gaps = 32/164 (19%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVL-----EMRRI- 393
+E +++++E+ EK++ +EE+ + +EEK +++E + K +++E+++ +MRR+
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369
Query: 394 -------QRAKEIED--------MNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQE 438
++ +E+E+ E R ++ R K++ +E RQ E++R+QE
Sbjct: 370 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429
Query: 439 ECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLE 482
E + RE+ K W ++ EK+ EQ+ +RE ++ E
Sbjct: 430 EKI--------REQEKKMW---RQEEKIHEQEKIREEEKRQEQE 462
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/177 (25%), Positives = 92/177 (51%), Gaps = 18/177 (10%)
Query: 338 RQKELQKQLEEKREKLKREEE-----RRKIEEEKEKKRENDIVFKAWLQKKREQVL---E 389
+ + ++ + EK EK++R EE KI E +EK E + + + +++ E+ + E
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 409
Query: 390 MRRIQRAK---EIEDMNSRENRDPQQAFRLW-LKKKHEEQMKERQTEELRKQEECLFFLK 445
R+ Q AK + E + +E + +Q ++W ++K EQ K R+ E+ ++QEE +
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MW 465
Query: 446 GTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
E + R ++ R+K EKM EQ+ +R++ ++ + ++ + + E K +R
Sbjct: 466 RQEEKIREQEEIWRQK--EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR 520
Score = 48.9 bits (115), Expect = 1e-05
Identities = 44/179 (24%), Positives = 89/179 (49%), Gaps = 23/179 (12%)
Query: 342 LQKQLEEK----REKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
L +Q EEK EK++ EE+ + +EEK +++E I + +++E+++ + + +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 398 EIEDMNSRENRDPQQAFRLW--------LKKKHEEQMKERQTEELRKQEECLFFLKGTEG 449
+ E M +E + + +W L++K EQ K R+ EE R++EE + + +
Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI--REQEKR 411
Query: 450 RERAFKQWLR----RKRMEKMAEQQAVRERT-----RQLRLEAKRSKQLQHHLYMSEAK 499
+E+ K W + R++ EK+ EQ+ R Q ++ + +Q Q ++ E K
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/197 (24%), Positives = 95/197 (48%), Gaps = 44/197 (22%)
Query: 338 RQKEL---QKQLEEKREKLKREEER--------R-----------KIEEEKEKKRENDIV 375
RQKE Q+++ ++ EK+ R+EE+ R KI E++EK RE +
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 376 FKAWLQKKREQVLEM-RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKER---QT 431
+ + +EQ +M + ++ +E E M +E + +Q ++ +K+ + +E+ Q
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 432 EELRKQEECLFFLKGTEGRERAFKQWLRRKRM----EKMAEQQAVRER------TRQLRL 481
E++R+QEE + +E+ K W + ++M EKM EQ+ R +++RL
Sbjct: 599 EKIREQEEMM--------QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
Query: 482 EAKRSKQLQHHLYMSEA 498
+ K +H ++ A
Sbjct: 651 RQQEEKMQEHQEHLEAA 667
Score = 46.6 bits (109), Expect = 5e-05
Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 29/137 (21%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
+ +++++Q+Q + +R++ K E+ KI E+KEK RE + K W Q+ E++ E +
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE--EKIWEQE--EKIREQEEMM 608
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
+ +E E M +E + +Q EE+M+E Q E++R+QE E+ +
Sbjct: 609 QEQE-EKMWEQEEKMCEQ----------EEKMQE-QEEKMRRQE------------EKMW 644
Query: 455 KQWLR-RKRMEKMAEQQ 470
+Q +R R++ EKM E Q
Sbjct: 645 EQEVRLRQQEEKMQEHQ 661
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/172 (22%), Positives = 81/172 (47%), Gaps = 18/172 (10%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
L L K+L+ KL+ + E ++ +++E K W Q+++ Q E + +
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE----KMWRQEEKIQEWEEKIQE 318
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
+ ++I + + + K + +E+M + E++R+QEE + + K + R
Sbjct: 319 QEEKIREQEEKIREQEE-------KMRRQEEMMWEKEEKMRRQEE-MMWEKEEKMRRLEE 370
Query: 455 KQWLRRKRM----EKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
W + +++ EKM EQ+ +RE+ + + E K +Q + EAK +R
Sbjct: 371 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ--EQEAKMWR 420
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 60.8 bits (146), Expect = 3e-09
Identities = 77/316 (24%), Positives = 136/316 (43%), Gaps = 34/316 (10%)
Query: 205 TNGSCEENKDRTILVERDGKFELLNLQDIASQGFLPPINNANSTENDPQQLLPRSSNSSV 264
T+G D + +G+ L+D+ SQ + A + + L + NS V
Sbjct: 59 TSGGYHSPGDSATGIYGEGRASSTTLEDLESQ--YQELAVALDSSSAIISQLTENINSLV 116
Query: 265 SGTKKEDSTAKIHAVTH---------SSTGEPLAYIAQPPLNRKTCPSSAVNSDRSKGNG 315
T KE+ +IH V + T EPLA +PP ++ +
Sbjct: 117 R-TSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLA--PEPPAGPSKVEQLQDETNHLRKEL 173
Query: 316 KSNHRTQSAHISPVTSTYCLSPRQ-----------KELQKQLEEKREKLKREEERRKIEE 364
+S R A + L+ RQ +E +++L E+ E+L +EER + +E
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQE 233
Query: 365 EKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEE 424
E+ +++E + + ++ E+ L + + ++ E + +E R +Q RL +++
Sbjct: 234 ERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR 293
Query: 425 QMKER---QTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRL 481
+ +ER Q E LR+QEE L E ER +Q R EK+ Q+ + E +L L
Sbjct: 294 EQEERLCEQEERLREQEERL-----CEQEERLREQEERLCEQEKLPGQERLLEEVEKL-L 347
Query: 482 EAKRSKQLQHHLYMSE 497
E +R ++ Q L E
Sbjct: 348 EQERRQEEQERLLERE 363
Score = 45.4 bits (106), Expect = 1e-04
Identities = 50/182 (27%), Positives = 92/182 (50%), Gaps = 25/182 (13%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKI-------EEEKEKKRENDI-VFKAWLQKKREQ 386
L L+K+LE +L+ E E ++ +EE+ +++E + + L+++ E+
Sbjct: 162 LQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEER 221
Query: 387 VLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKER------QTEELRKQEEC 440
+ E R +E E + +E R +Q RL ++HEE++ E+ Q E LR+QEE
Sbjct: 222 LCEQEERLREQE-ERLREQEERLCEQEERL---REHEERLCEQEERLCEQEERLREQEER 277
Query: 441 LFFLKGTEGRERAFKQWLR-RKRMEKMAEQ-QAVRERTRQLRLEAKRSKQLQHHLYMSEA 498
L E ER +Q R R++ E++ EQ + +RE+ +L + +R ++ + L E
Sbjct: 278 LH-----EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEK 332
Query: 499 KP 500
P
Sbjct: 333 LP 334
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/142 (25%), Positives = 75/142 (52%), Gaps = 2/142 (1%)
Query: 341 ELQKQLEEKREKLKREEERRKIEEEKEKKRENDIV-FKAWLQKKREQVLEMRRIQRAKEI 399
E +++L E+ E+L +EER +EE+ +++E + + L+++ E++ E R +E
Sbjct: 266 EQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQE- 324
Query: 400 EDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLR 459
E + +E Q+ ++K E++ ++ + E L ++E L ++ +ER +Q R
Sbjct: 325 ERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDER 384
Query: 460 RKRMEKMAEQQAVRERTRQLRL 481
+ E + E + +RE R L L
Sbjct: 385 LWQQETLQELERLRELERMLEL 406
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 58.9 bits (141), Expect = 1e-08
Identities = 44/178 (24%), Positives = 98/178 (55%), Gaps = 19/178 (10%)
Query: 335 LSPRQKELQKQLE---EKREKLKREEERRKIEEEKEKKR-----ENDIVFKAWLQKKREQ 386
+ R++++Q+Q E E+ EK++R+EE +EEK +++ E + + +K EQ
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 356
Query: 387 VLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKG 446
+ ++ +E E + +E R Q+A ++W + EE+++E Q E++R+QEE + +
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEA-KMW---RQEEKIRE-QEEKIREQEEMMQEQEE 411
Query: 447 TEGRERAFKQWLRRKRMEKMAE-----QQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
G E+ K W + + M++ E ++ +RE+ +++R + ++ ++ + + E K
Sbjct: 412 KMG-EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Score = 54.3 bits (129), Expect = 3e-07
Identities = 42/172 (24%), Positives = 98/172 (56%), Gaps = 10/172 (5%)
Query: 338 RQKELQKQLEEK-REKLKREEERRKI--EEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
R++E ++Q EEK RE+ KR+E+ K+ +EEK +++E I + + +++E+ + + +
Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419
Query: 395 RAKEIEDMNSREN--RDPQQAFRLWLKKKHEEQMKERQTEE-LRKQEECLFFLKG----T 447
++ E+M +E R ++ R KK E++ K R+ EE +++QEE + +G
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 448 EGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
E + + ++ +RR+ + +++ +RE+ ++R + + ++ + ++ E K
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Score = 53.1 bits (126), Expect = 6e-07
Identities = 47/168 (27%), Positives = 92/168 (54%), Gaps = 34/168 (20%)
Query: 339 QKELQKQLEEK---REKLKREEERRKIEE---EKEKKRENDIVFKAWLQKKREQVLEMRR 392
++E ++LEEK +EK++ +EE+R+ EE E+EK++E + K W Q+ E++ E
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMWRQE--EKIREQEE 397
Query: 393 IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
R +E E M +E + +Q ++W + EE+M+E Q E++R+QEE +
Sbjct: 398 KIREQE-EMMQEQEEKMGEQEEKMW---EQEEEMQE-QEEKMRRQEEKI----------- 441
Query: 453 AFKQWLRRKRMEKMAEQQA-VRERTRQLRLEAKRSKQLQHHLYMSEAK 499
R++ +K+ EQ+ +RE+ ++ + ++ + + + EAK
Sbjct: 442 -------REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Score = 51.2 bits (121), Expect = 2e-06
Identities = 43/179 (24%), Positives = 92/179 (51%), Gaps = 35/179 (19%)
Query: 340 KELQKQLEEKREKLKREEER-----RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
+E ++ ++E+ EK+ +EE+ +++E++EK R + + +K REQ ++R +
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459
Query: 395 R--AKEIEDMNSRENRDPQQAFRLWLK----KKHEEQMKER------QTEELRKQEECLF 442
++ E M +E + +Q ++ + ++ EE+++E+ Q E++R+QEE +
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM- 518
Query: 443 FLKGTEGRERAFKQWLRRKRM----EKMAEQ------QAVRERTRQLRLEAKRSKQLQH 491
+E+ K W + ++M EKM EQ Q + R +++RL + K +H
Sbjct: 519 -------QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 47.0 bits (110), Expect = 4e-05
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 19/150 (12%)
Query: 338 RQKELQKQLEEKREKLKREEER-----RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRR 392
+ + ++++ E+ +K++ +EE+ ++E++EK E + K +EQ +MRR
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 393 IQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRER 452
+ ++ RE + K + +E+M + Q E++ +QEE K E E+
Sbjct: 493 QEEKIREQEKKIREQEE---------KIREQEEMMQEQEEKMWEQEE-----KMCEQEEK 538
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLE 482
+Q + +R E+ +Q VR R ++ +++
Sbjct: 539 MQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 31.2 bits (69), Expect = 2.3
Identities = 31/159 (19%), Positives = 72/159 (45%), Gaps = 22/159 (13%)
Query: 1 MNENKDTDSKKSEEYEDDFEK--DLEWLINENEKSDASIIEMACEKEENINQDLKENETV 58
M E ++ ++ EE ++ EK E I E EK E E+EE + + + E +
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE---QEEKM 469
Query: 59 MEHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEE 118
E + + + +Q++ R + I + + + QE K+ Q+++ +E
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQE---------EKIREQEKKIREQEEKIREQEEMMQE 520
Query: 119 EDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQ 157
++E++ Q K+ + +E + ++ E K++ +++
Sbjct: 521 QEEKMWE-------QEEKMCEQEEKMQEQEE-KMRRQEE 551
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/177 (23%), Positives = 94/177 (53%), Gaps = 19/177 (10%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEI 399
+E +++++E+ EK++ +EE+ + +EEK +++E + K +++E+++ + + ++
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369
Query: 400 EDMNSRENRDPQQAFRLW--------LKKKHEEQMKERQTEELRKQEECLFFLKGTEGRE 451
E M +E + +Q +W L++K EQ K R+ EE R++EE + + + +E
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI--REQEKRQE 427
Query: 452 RAFKQWLR----RKRMEKMAEQQAVRERT-----RQLRLEAKRSKQLQHHLYMSEAK 499
+ K W + R++ EK+ EQ+ R Q ++ + +Q Q ++ E K
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 484
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/163 (24%), Positives = 87/163 (53%), Gaps = 21/163 (12%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+ + ++ + EK EK++R+EE E+E++ +R+ +++++ + +R++ + + ++ +
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEE-MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
Query: 398 EIED--------MNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEG 449
E+E+ E R ++ R K++ +E RQ E++R+QEE +
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI-------- 446
Query: 450 RERAFKQWLRRKRMEKMAEQQAVR-ERTRQLRLEAKRSKQLQH 491
RE+ K W ++ EK+ EQ+ +R E RQ + E R ++ H
Sbjct: 447 REQEKKMW---RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
Score = 57.4 bits (137), Expect = 3e-08
Identities = 50/162 (30%), Positives = 86/162 (53%), Gaps = 23/162 (14%)
Query: 338 RQKELQKQLEEK-REKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM-RRIQR 395
R++E ++Q EEK RE+ KR+E+ K+ ++EK RE + +K REQ +M R+ ++
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE-------EKIREQEKKMWRQEEK 459
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFK 455
E E + E R Q+ +K HE++ RQ E++ +QEE K + E+ ++
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE-----KIRKQEEKVWR 514
Query: 456 QWLR-RKRMEKMAEQ--------QAVRERTRQLRLEAKRSKQ 488
Q + R++ EK+ EQ + +RE+ R E K +Q
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Score = 57.4 bits (137), Expect = 3e-08
Identities = 47/176 (26%), Positives = 98/176 (55%), Gaps = 15/176 (8%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM-RRIQRA 396
+++++ +Q E R+K K E+ KI +++EK + + +K REQ +M R+ ++
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 397 KEIEDMNSRENRDPQQAFRLWLKKKHEEQMKE--RQTEELRKQEECLFFL---------K 445
+E E+M E + +Q ++W ++K +EQ + RQ E++R+QEE ++ K
Sbjct: 541 REQEEMWREEEKMHEQE-KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
Query: 446 GTEGRERAFKQWLR-RKRMEKMAEQ-QAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
E E+ +KQ + R++ EK+ EQ + +RE+ ++R + + +++ + + E K
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Score = 55.1 bits (131), Expect = 2e-07
Identities = 47/156 (30%), Positives = 84/156 (53%), Gaps = 23/156 (14%)
Query: 342 LQKQLEEK----REKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
L +Q EEK EK++ EE+ + +EEK +++E +K REQ +MRR
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---------EKIREQEEKMRR----- 339
Query: 398 EIEDMNSRENRDPQQAFRLWLKK---KHEEQMKERQTEELRKQEECLFFL--KGTEGRER 452
+ E M +E + +Q +W K+ + +E+M + E++R+QEE ++ K E E+
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399
Query: 453 AFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+Q R++ EK E++ +RE+ ++ EAK +Q
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/185 (27%), Positives = 89/185 (48%), Gaps = 39/185 (21%)
Query: 338 RQKELQKQLEEK----REKLKREEERRKIEEEK-----EKKRENDIVFKAWLQKKREQVL 388
RQ+E ++ EEK EK++ +EE+R+ +EEK EK RE + + +K REQ
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE 633
Query: 389 EMRRIQR---------AKEIEDMNSRENRDPQQAFRLWL---KKKHEEQMKERQTEELRK 436
++R + ++ E M +E + +Q +W K + +E+ Q E++R+
Sbjct: 634 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693
Query: 437 QEECLFFLKGTEGRERAFKQWLRRKRM----EKMAEQQAVRER------TRQLRLEAKRS 486
QEE + +E+ K W + ++M EKM EQ+ R +++RL +
Sbjct: 694 QEEMM--------QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Query: 487 KQLQH 491
K +H
Sbjct: 746 KMQEH 750
Score = 52.0 bits (123), Expect = 1e-06
Identities = 47/225 (20%), Positives = 103/225 (45%), Gaps = 29/225 (12%)
Query: 296 LNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKR 355
L K + K + R Q + + +E ++++ E+ +K+ R
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 356 EEER----RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQ 411
+EE+ KI EE++++ + ++ W Q+ E++ E I R KE M+ +E + +
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEM----WRQE--EKIHEQEEIWRQKE--KMHEQEEKIRK 507
Query: 412 QAFRLWLK----KKHEEQMKE------RQTEELRKQEECLFFLKGTEGRERAFKQWLRRK 461
Q ++W + ++ EE+++E RQ E++R+QEE + E K W K
Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE---MWREEEKMHEQEKIWEEEK 564
Query: 462 RMEK----MAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
R E+ +++ +RE+ ++ + ++ ++ + E K ++
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Score = 51.2 bits (121), Expect = 2e-06
Identities = 38/172 (22%), Positives = 89/172 (51%), Gaps = 27/172 (15%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+ + ++ + EK EK++R+EE +EEK ++ E +K EQ + ++ +
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE---------EKMHEQEKIREQEEKRQ 414
Query: 398 EIEDMNSRENRDPQQAFRLWLK----KKHEEQMKE------RQTEELRKQEECLFFLKGT 447
E E + +E R Q+A ++W + ++ EE+++E RQ E++ +QE+ ++
Sbjct: 415 EEEKIREQEKRQEQEA-KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK----IREE 469
Query: 448 EGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
E R+ + W ++ EK+ EQ+ + + ++ + ++ ++ + ++ E K
Sbjct: 470 EKRQEQEEMW---RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Score = 49.7 bits (117), Expect = 6e-06
Identities = 37/174 (21%), Positives = 93/174 (53%), Gaps = 17/174 (9%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+++++++Q E RE+ K E+ + EEEK +++E+ K W Q+++ + E + ++ +
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED----KMWRQEEKIREQEEKVWRQEE 591
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQW 457
+I + + ++ ++ K + +E+ + Q E++R+QEE + + +E+ K
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT-QEQEEKMG 650
Query: 458 LRRKRM----EKMAEQ--------QAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+ ++M EKM EQ + +RE+ +++R + ++ ++ + + E K
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 704
Score = 45.8 bits (107), Expect = 9e-05
Identities = 35/157 (22%), Positives = 78/157 (49%), Gaps = 6/157 (3%)
Query: 343 QKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDM 402
+++ +E+ +K+ R+EE KI E++EK + + +K++EQ E + ++ ++I +
Sbjct: 562 EEKRQEQEDKMWRQEE--KIREQEEKVWRQEEKIREQEEKRQEQ--EEKMWKQEEKIREQ 617
Query: 403 NSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEE--CLFFLKGTEGRERAFKQWLRR 460
+ ++ K + +E+M + Q E++ +QEE C K E E ++Q +
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677
Query: 461 KRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSE 497
+ EK +Q + R ++ ++ + K + M E
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714
Score = 42.7 bits (99), Expect = 8e-04
Identities = 40/191 (20%), Positives = 83/191 (43%), Gaps = 42/191 (21%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKI-----EEEKEKKRENDIVFKAWLQKKREQVLE 389
L L K+L+ KL+ + E ++ ++++EK + + W +K +EQ +
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 390 MRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEG 449
+R ++ ++I + + R + + K + +E+M + E++R+QEE +
Sbjct: 323 IR--EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM-------- 372
Query: 450 RERAFKQWLRRKRM------------------EKMAEQQAVRERTRQLRLEAKRSKQLQH 491
W + ++M EKM EQ+ +RE+ + + E K +Q +
Sbjct: 373 -------WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 425
Query: 492 HLYMSEAKPFR 502
EAK +R
Sbjct: 426 Q--EQEAKMWR 434
Score = 36.6 bits (83), Expect = 0.055
Identities = 28/148 (18%), Positives = 70/148 (47%), Gaps = 14/148 (9%)
Query: 1 MNENKDTDSKKSEEYEDDFEK--DLEWLINENEKSDASIIEMACEKEENINQDLKENETV 58
+ E ++ ++ E+ + EK + E + E E+ E CE+EE + + + ET+
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE---QEETM 670
Query: 59 MEHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEE 118
++ + +K ++++ R + + + + + + QE K+ Q++ +E
Sbjct: 671 WRQEEKIREQEKKIREQEEKIR---------EQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Query: 119 EDEEVRRYIMEKIVQANKLLQNQEPVND 146
++E++RR + Q +L Q +E + +
Sbjct: 722 QEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 31.6 bits (70), Expect = 1.8
Identities = 30/178 (16%), Positives = 78/178 (43%), Gaps = 25/178 (14%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEK---SDASIIEMACEKEENINQDLKENETVM 59
+ K + +K +E ED + E + + EK + I E +++E + K+ E +
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 60 EHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEE 119
E ++ + ++ ++++ R + + + + + + QE K++ Q++ +
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQ--EQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 120 DEEVR------RYIMEKIVQANKLLQNQEPVN--------------DKRERKLKFKDQ 157
+E++R R EKI + +++Q QE ++E K++ +++
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 58.2 bits (139), Expect = 2e-08
Identities = 48/163 (29%), Positives = 86/163 (52%), Gaps = 24/163 (14%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM------- 390
R++E Q++ E +RE+ ++ E R+ E E+E++RE + + ++KR++ EM
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 391 ------RRIQRAKEIE---DMNSRENRDPQQAFRLWLKKKHEEQMKE------RQTEELR 435
R+ +R +E E D S R+ ++ R ++K E+ E R+TE+ R
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418
Query: 436 KQEECLFFLKGTE-GRERAFKQWLRRKRMEKMAEQQAVRERTR 477
++E+ +G E GRER KQ R + E+ ++QA R+R R
Sbjct: 419 EREKDRESERGRERGRERE-KQKGRERDRERQTDRQAGRQRKR 460
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/199 (26%), Positives = 89/199 (44%), Gaps = 9/199 (4%)
Query: 293 QPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREK 352
Q R+T DR + R + A T RQ E +Q E +REK
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK 183
Query: 353 LKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEM---RRIQRAKEIEDMNSRENRD 409
++E R+ + EKE K E D + +++RE+ E R+ Q +E + E
Sbjct: 184 NRQERRERERQREKENKTE-DRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
Query: 410 PQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQ 469
+QA R ++ E+ KER+ E R ++ + + RER + R++R E+ E
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRD----RRQKERERQTDR-KRQRRTERDRET 297
Query: 470 QAVRERTRQLRLEAKRSKQ 488
+ RER R+ E +R+++
Sbjct: 298 ERKRERQRERERERERNRK 316
Score = 54.3 bits (129), Expect = 3e-07
Identities = 47/182 (25%), Positives = 85/182 (46%), Gaps = 14/182 (7%)
Query: 310 RSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEKEKK 369
R + K HR + H R+KE ++Q + +R++ +RE+ER + +KE++
Sbjct: 79 RERRREKDRHRKRDRHRERQRD------REKERERQTDRERDR-QREKERNR---QKERE 128
Query: 370 RENDIVFKAWLQKKREQVLEMRRIQRA-KEIEDMNSRENRDPQQAFRLWLKKKHEEQMKE 428
RE + + ++ + E R + A KE E RE + + R +++ + + +
Sbjct: 129 RETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQER 188
Query: 429 RQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
R+ E R++E GRER + R E ++Q RER RQ + E +R KQ
Sbjct: 189 RERERQREKENKTEDRHSERGRERERE---RETETETERKRQTDRERDRQRKTEREREKQ 245
Query: 489 LQ 490
+
Sbjct: 246 AE 247
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/185 (24%), Positives = 90/185 (48%), Gaps = 9/185 (4%)
Query: 308 SDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEKE 367
+DR + + R + ++ + R KE +++ + R++ +R++ER E + +
Sbjct: 228 TDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER---ERQTD 284
Query: 368 KKRENDIVFKAWLQKKREQVLEM-RRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQM 426
+KR+ ++KRE+ E R +R ++ E RE +Q ++K E+
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 427 KERQTEELRKQEECLFFLKGTEGRERAFKQWLR-RKRMEKMAEQQAVRERTRQLRLEAKR 485
++RQTE R++ G EGR +A ++ R R+R + A ++ RER R + +R
Sbjct: 345 RKRQTEMDRERNR----QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER 400
Query: 486 SKQLQ 490
+Q +
Sbjct: 401 ERQTE 405
Score = 53.5 bits (127), Expect = 4e-07
Identities = 45/157 (28%), Positives = 80/157 (50%), Gaps = 17/157 (10%)
Query: 338 RQKELQKQLEEKREKLKREEER-RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRA 396
RQ+E + + E++ + RE ER R+ E E E+KR+ D + +RE+ + R +RA
Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER-ERA 251
Query: 397 KEIEDMNSRE-----NRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRE 451
E E +E +RD + R +++ ++ ++R+TE R+ E K RE
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER-----KRERQRE 306
Query: 452 RAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
R ++ RKR E++ RER R+ + E +R ++
Sbjct: 307 RERERERNRKR-----ERERERERERERQRETERDRE 338
Score = 52.8 bits (125), Expect = 7e-07
Identities = 44/157 (28%), Positives = 80/157 (50%), Gaps = 16/157 (10%)
Query: 338 RQKELQKQLEEKREKLKREEER---RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
R+KE +Q E +RE +RE ER R+ + ++E++R+ D + Q RE+ + R
Sbjct: 117 REKERNRQKERERET-EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER-N 174
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKK---KHEEQMKERQTEELRKQEECLFFLKGTEGRE 451
R KE E +R+ R ++ R K +H E+ +ER+ E + E TE +
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETE--------TERKR 226
Query: 452 RAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ ++ R+++ E+ E+QA RER + E + ++
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Score = 49.3 bits (116), Expect = 8e-06
Identities = 40/159 (25%), Positives = 77/159 (48%), Gaps = 10/159 (6%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
R +E +++ E +RE+ + E RK E+E++RE + + ++ RE+ E +R ++ +
Sbjct: 293 RDRETERKRERQRERERERERNRK--RERERERERERERQRETERDREKERERKRKRQTE 350
Query: 398 EIEDMNSRENRD-PQQAFRLWLKKKHEEQMKERQTEEL-------RKQEECLFFLKGTEG 449
+ N + R+ +QA R +++ ++ R+ EE R++E K +G
Sbjct: 351 MDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDG 410
Query: 450 RERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ KQ R K E ++ RER +Q E R +Q
Sbjct: 411 QRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/157 (27%), Positives = 72/157 (45%), Gaps = 21/157 (13%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQ 394
L K+ E+ + +RE R K + E+E R+ + + +KR++ E +R
Sbjct: 42 LGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQR-D 100
Query: 395 RAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAF 454
R KE E RE RD Q+ K+++ ++ +ER+TE +G GR+R
Sbjct: 101 REKERERQTDRE-RDRQRE-----KERNRQKERERETER-----------EGERGRDRQT 143
Query: 455 KQWLRRKRM---EKMAEQQAVRERTRQLRLEAKRSKQ 488
R+R EK E+Q RER RQ ++ ++
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKERE 180
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/168 (25%), Positives = 92/168 (54%), Gaps = 13/168 (7%)
Query: 335 LSPRQKELQKQLE---EKREKLKREEERRKIEEEKEKKRENDI-VFKAWLQKKREQVLEM 390
+ +++++QKQ E E+ E+++++EE+ +EE+ +K+E + + ++K+ EQ+ E
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
Query: 391 RRIQRAKEIEDMNSRE--NRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTE 448
R +E + + +E ++ Q + ++ EEQM+E Q E++R+QEE + +
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE-QEEQMREQEEQMREQEEQM 326
Query: 449 GR------ERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQ 490
G+ E+ + W ++++M K EQ +E Q + E R ++ Q
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
Score = 53.1 bits (126), Expect = 6e-07
Identities = 41/182 (22%), Positives = 99/182 (54%), Gaps = 29/182 (15%)
Query: 338 RQKELQKQLEEKREKLK--REEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQR 395
++++++KQ E+ RE+ + RE+E + ++++++ ++E + +++E+ + + Q
Sbjct: 253 QEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQM 312
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKK-----------KHEEQMKE------RQTEELRKQE 438
++ E M +E + +Q ++W +K K EEQM E +Q E++RKQE
Sbjct: 313 REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE 372
Query: 439 ECLFFLKGTEGRERAFKQWLRR------KRMEKMAEQ-QAVRERTRQLRLEAKRSKQLQH 491
E ++ E + R ++ +R+ ++ E+M EQ + +RE+ Q+ + ++ ++ +
Sbjct: 373 E---QMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Query: 492 HL 493
H+
Sbjct: 430 HM 431
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/158 (24%), Positives = 84/158 (53%), Gaps = 15/158 (9%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEI 399
+E + Q+ E+ ++ +EE+ +EE+ +K+E + + +K+E+ + + Q K+
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 400 EDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLR 459
E + +E + +K EEQM+E Q E++R+QEE + LK E E+ + +
Sbjct: 248 EQVQKQEEQ----------MRKQEEQMRE-QEEQMREQEEQM--LKQKEQTEQEEQTGEQ 294
Query: 460 RKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSE 497
++M + EQ +RE+ Q+R + ++ ++ + + E
Sbjct: 295 EEQMREQEEQ--MREQEEQMREQEEQMREQEEQMGKQE 330
Score = 49.7 bits (117), Expect = 6e-06
Identities = 41/159 (25%), Positives = 85/159 (53%), Gaps = 17/159 (10%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEI 399
+E + Q+ E+ ++ +E + +EE+ ++E +QK+ EQ+ E Q K+
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ------MQKQEEQMGEQEE-QMRKQE 233
Query: 400 EDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLR 459
E M +E + +Q ++ +K EEQM+ +Q E++R+QEE + E E+ KQ +
Sbjct: 234 EQMGEQEEQVQKQEEQV---QKQEEQMR-KQEEQMREQEEQM-----REQEEQMLKQKEQ 284
Query: 460 RKRMEKMAEQ-QAVRERTRQLRLEAKRSKQLQHHLYMSE 497
++ E+ EQ + +RE+ Q+R + ++ ++ + + E
Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Score = 35.8 bits (81), Expect = 0.095
Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 35/108 (32%)
Query: 335 LSPRQKELQKQLEEKR---EKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMR 391
+ +++++QKQ E+ R E+++++EE+ + +EE+ +K+E + +++EQ+ E +
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ------MGEQKEQMGEQK 407
Query: 392 RIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEE 439
R + EEQM E Q E++RKQEE
Sbjct: 408 EQMR-------------------------EQEEQMGE-QKEQMRKQEE 429
Score = 32.0 bits (71), Expect = 1.4
Identities = 21/156 (13%), Positives = 71/156 (45%), Gaps = 7/156 (4%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHT 62
E ++ E E+ + E ++ + E+++ E E+EE + + ++ E
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE--EQTGEQEEQMREQEEQMREQEEQM 312
Query: 63 KRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEE 122
+ + + ++++ + + + + + + + QE ++ Q++ ++++E+
Sbjct: 313 REQEEQMREQEEQMGKQEEQMW-----EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ 367
Query: 123 VRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQL 158
VR+ + Q ++ + +E + + E+ + K+Q+
Sbjct: 368 VRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM 403
Score = 30.8 bits (68), Expect = 3.0
Identities = 12/65 (18%), Positives = 38/65 (58%)
Query: 93 DPISDSDSENSFQESKLESQKDLEEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKL 152
+ + + + + QE ++ Q++ ++++E+V++ + Q ++ + +E + ++ E+ L
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
Query: 153 KFKDQ 157
K K+Q
Sbjct: 280 KQKEQ 284
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 57.4 bits (137), Expect = 3e-08
Identities = 61/236 (25%), Positives = 105/236 (44%), Gaps = 20/236 (8%)
Query: 267 TKKEDSTAKIHAVTH--SSTGEPLAYIAQPPLNRKTCPSSAVNS--DRSKGNGKSNHRTQ 322
T KE+ IH + S E +A+PP +S V D +K + +
Sbjct: 256 TLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLE 315
Query: 323 SAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEK-----EKKRENDIVFK 377
S V + LS KE +++L+E+ E L+ +E +R E+E+ E+ RE +
Sbjct: 316 GKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQ 375
Query: 378 AWLQKKREQVLEMRRIQRA--KEIEDMNSRENRDPQQAFRLWLK----KKHEEQMKERQT 431
++ R+Q +R+ + KE E + +E R Q RLW K +K EE++ Q
Sbjct: 376 EQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQN 435
Query: 432 EELRKQ---EECLFFLKGTEGRERAFKQWLRRKRMEKMAEQ--QAVRERTRQLRLE 482
+L KQ +C F E + + ++ EK+ E+ +A +R +QL +
Sbjct: 436 HKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 57.4 bits (137), Expect = 3e-08
Identities = 41/173 (23%), Positives = 88/173 (50%), Gaps = 26/173 (15%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDI----------VFKAWLQKKR--- 384
R +E +K++ E+ E ++ +EE+ + +EEK +++E + K W Q+++
Sbjct: 6 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE 65
Query: 385 --EQVLEMRRIQRAKE---IEDMNSRENRDPQQAFRLWL-------KKKHEEQMKERQTE 432
E++ E +R+ KE +D RE + + ++W KKK +E+ + Q E
Sbjct: 66 QEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEE 125
Query: 433 ELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
++++QEE + + + + +E+ K W + ++M + E+ +E Q + E R
Sbjct: 126 KMQEQEE-MMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
Score = 49.7 bits (117), Expect = 6e-06
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 18/163 (11%)
Query: 350 REKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRD 409
RE+ + E +K+ EE+E RE + + +K REQ +M ++ E M +E +
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM-----WEQEEKMQEQEEKM 56
Query: 410 PQQAFRLW--LKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRM---- 463
+Q ++W +K E+Q Q E++ +Q+E L+ E R R K W + ++M
Sbjct: 57 WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDE---RLREKEERMREQKMWQQVEKMREKK 113
Query: 464 ----EKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
EKM EQ+ + ++ E + Q Q + + R
Sbjct: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 156
Score = 34.7 bits (78), Expect = 0.21
Identities = 22/101 (21%), Positives = 57/101 (56%), Gaps = 13/101 (12%)
Query: 338 RQKELQKQLEEKREKLKREEE-----RRKIEEEKEKKRENDIVFKAWLQKKREQVLEMR- 391
++K +++++E+ EK++ +EE K++E++EK E + + +K REQ +M+
Sbjct: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171
Query: 392 RIQRAKEIE-------DMNSRENRDPQQAFRLWLKKKHEEQ 425
+ ++ +++E + + ++N Q+ +L+ K+ +Q
Sbjct: 172 QEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQ 212
Score = 34.3 bits (77), Expect = 0.28
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 12/81 (14%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKREN----------DIVFKAWLQ--KKRE 385
R++++ +Q+E+ REK K +EE+ + +EEK +++E + K W Q K RE
Sbjct: 98 REQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 157
Query: 386 QVLEMRRIQRAKEIEDMNSRE 406
Q +MR + + ++ R+
Sbjct: 158 QEEKMREQEEKMQGQEEKMRD 178
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 57.4 bits (137), Expect = 3e-08
Identities = 61/236 (25%), Positives = 105/236 (44%), Gaps = 20/236 (8%)
Query: 267 TKKEDSTAKIHAVTH--SSTGEPLAYIAQPPLNRKTCPSSAVNS--DRSKGNGKSNHRTQ 322
T KE+ IH + S E +A+PP +S V D +K + +
Sbjct: 256 TLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLE 315
Query: 323 SAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEK-----EKKRENDIVFK 377
S V + LS KE +++L+E+ E L+ +E +R E+E+ E+ RE +
Sbjct: 316 GKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQ 375
Query: 378 AWLQKKREQVLEMRRIQRA--KEIEDMNSRENRDPQQAFRLWLK----KKHEEQMKERQT 431
++ R+Q +R+ + KE E + +E R Q RLW K +K EE++ Q
Sbjct: 376 EQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQN 435
Query: 432 EELRKQ---EECLFFLKGTEGRERAFKQWLRRKRMEKMAEQ--QAVRERTRQLRLE 482
+L KQ +C F E + + ++ EK+ E+ +A +R +QL +
Sbjct: 436 HKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 57.4 bits (137), Expect = 3e-08
Identities = 47/167 (28%), Positives = 90/167 (53%), Gaps = 20/167 (11%)
Query: 338 RQKELQKQ--LEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQR 395
RQK +Q+Q LE KR + +R RR+I E+ EK +E + ++++EQ+LE +
Sbjct: 236 RQKSIQRQEELERKRRE-ERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQ 294
Query: 396 AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEE-----CLFFLKGTEGR 450
++++DM R+ QQ ++ + K ++Q EL QE+ + F K R
Sbjct: 295 EEDLKDMERRQ----QQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAR 350
Query: 451 ERAF---KQWLRRKRMEKMAEQQAVRERTR-----QLRLEAKRSKQL 489
E F ++ +RR++ +++A +A++E+ + Q L AKR++++
Sbjct: 351 EAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEV 397
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 18/152 (11%)
Query: 343 QKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDM 402
Q +E ++K+ RE E +E +++E +I +Q+K + + RAK +++
Sbjct: 338 QMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEV 397
Query: 403 NSRENRDPQQAFRLWLKKKHEEQMKERQTE-ELRKQEECLFFLKGTEGRERAFKQWLRRK 461
RE W +K+ E K+ +TE ELRK L+ +E A ++R
Sbjct: 398 ADRE----------WRRKEKENARKKMETEAELRKSR-----LEQVAFKEHALAVQVQRD 442
Query: 462 RMEKMAEQQAVRERTRQLRL--EAKRSKQLQH 491
R E +A RE+ + RL E K + +LQH
Sbjct: 443 RDEFERILRAQREQIEKERLEEEKKATGRLQH 474
Score = 43.5 bits (101), Expect = 5e-04
Identities = 33/154 (21%), Positives = 79/154 (51%), Gaps = 9/154 (5%)
Query: 341 ELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKRE-QVLEMRRIQR---- 395
+L++ +E+ + L + + ++E+E+E K + I+ A R+ Q+LE ++IQ+
Sbjct: 164 DLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDT 223
Query: 396 -AKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQ--TEELRK-QEECLFFLKGTEGRE 451
K ++ M E + Q +K+ EE+++ R+ E++ K QEE + E +
Sbjct: 224 EEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEK 283
Query: 452 RAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKR 485
+++ + + E + + + +++ +++ E KR
Sbjct: 284 EQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKR 317
Score = 42.0 bits (97), Expect = 0.001
Identities = 97/495 (19%), Positives = 197/495 (39%), Gaps = 79/495 (15%)
Query: 17 DDFEKDLEWLINENEKSDASIIEMACEKEENINQD--------LKENETVMEHTKRHSDP 68
++FE+ ++W + + + + A +KE+ D +K+ E V + K+ SD
Sbjct: 107 EEFER-IKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDL 165
Query: 69 DKSLQDEVSP--RRNDIISVPGIQPLDPISD---SDSENSFQESKLESQKDLEEEEDEEV 123
++ ++ +R + + + + L +S + ++ +++++ ++ +++E D E
Sbjct: 166 EEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEE 225
Query: 124 RRYIMEKIVQANKLLQNQEPVNDKR-ERKLKFKDQLVDLEVPPLEDTTTFKNYFENERNM 182
+R V+ K +Q QE + KR E +++ + Q+V+ E+ + E E+
Sbjct: 226 KRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEK-- 283
Query: 183 FGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLPPI 242
E +L + E+ KD E Q + Q + I
Sbjct: 284 ---------------EQMLEYMEQLQEEDLKD----------MERRQQQKLKMQAEIKRI 318
Query: 243 NNANSTENDPQQLLPRSSNSSVS--GTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKT 300
N+ N + + ++ V KK A+ A E IA+ ++
Sbjct: 319 NDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEK 378
Query: 301 CPSSAVNSD--RSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEE 358
D R+K N + R R+KE E R+K++ E E
Sbjct: 379 AQDYQAEQDALRAKRNQEVADREW---------------RRKE----KENARKKMETEAE 419
Query: 359 RRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWL 418
RK E+ +E+ + + +Q+ R+ E RI RA+ + R + + RL
Sbjct: 420 LRKSRLEQVAFKEHALAVQ--VQRDRD---EFERILRAQREQIEKERLEEEKKATGRLQH 474
Query: 419 KKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQ 478
+ Q++E Q +E+ Q F +G +E A K RR+R++++ ++ R
Sbjct: 475 ANELRRQVRENQQKEV--QNRIATFEEGRRLKEEAQK---RRERIDEIKRKKLEELRATG 529
Query: 479 LR----LEAKRSKQL 489
L +EA+R +
Sbjct: 530 LPEKYCIEAERKANI 544
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 56.6 bits (135), Expect = 5e-08
Identities = 46/171 (26%), Positives = 90/171 (52%), Gaps = 12/171 (7%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEI 399
++LQKQ + + K ++++ EEK K++E + K + KR Q + M + RA++I
Sbjct: 905 RKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQI 964
Query: 400 EDMNSRENRDPQQAFRLWLKKK-HEEQMKERQTEELRKQE-----ECLFFLKGTEGRERA 453
+ ++ + A L +K+ E++M+ +Q L+ QE + + +K E R++A
Sbjct: 965 LEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKA 1024
Query: 454 FKQWLRRKRMEKMAEQQAVRER---TRQLRLE-AKRSKQLQHHLYMSEAKP 500
++ R + EK E++ +ER R+L LE AK K+ + +++ KP
Sbjct: 1025 EEK--ERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKP 1073
Score = 37.4 bits (85), Expect = 0.032
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 10/107 (9%)
Query: 2 NENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEH 61
+E +D + + E+ EDD D + + N +SD E E +++ +QD +++T E
Sbjct: 610 DEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEE--EDDDDKDQDESDSDTEGEK 667
Query: 62 TKRH--------SDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDS 100
T P SL +PR I PG P S+S S
Sbjct: 668 TSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQS 714
Score = 30.0 bits (66), Expect = 5.2
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 10/61 (16%)
Query: 62 TKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDE 121
T+ HS P KSL ++ +DI P S +++ E + + ++D E++ED+
Sbjct: 577 TQHHSHPAKSLVEQFRGTDSDI----------PSSKDSEDSNEDEEEDDEEEDEEDDEDD 626
Query: 122 E 122
E
Sbjct: 627 E 627
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 56.2 bits (134), Expect = 7e-08
Identities = 37/132 (28%), Positives = 72/132 (54%), Gaps = 14/132 (10%)
Query: 344 KQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMN 403
K+ ++K+++ + EE + EEE+EK+ + +K++E+ E + ++ KE E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRK-------EKRKEKRKEKEKKKKTKETEKRK 53
Query: 404 SRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRM 463
+E + ++ + KK+ EE+ +E + EE K+EE + EGR R K+ +R+R
Sbjct: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE-----EKEEGRRRKKKK--KRRRK 106
Query: 464 EKMAEQQAVRER 475
E+ E++ R R
Sbjct: 107 EEEEEKKKKRRR 118
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/99 (28%), Positives = 57/99 (57%), Gaps = 5/99 (5%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
++K +K+ E++++K +E E+RK +EE+EKKR+ + +KK E+ E + +
Sbjct: 30 KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK-----RKRKKKKEEEEREEEEEEEEE 84
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRK 436
E E+ E R ++ + K++ EE+ K+R+ + +K
Sbjct: 85 EKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/101 (22%), Positives = 61/101 (60%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKE 398
++E + + +EKR++ ++E+E++K +E EK++E + K +K++++ E R + +E
Sbjct: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE 81
Query: 399 IEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEE 439
E+ E ++ + + K++ +E+ +E++ + RK ++
Sbjct: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 43.5 bits (101), Expect = 5e-04
Identities = 33/141 (23%), Positives = 75/141 (53%), Gaps = 33/141 (23%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEI 399
+E ++ EE+ ++ KR+E+R++ +EKEKK++ K +K++E+ + R+ +R K+
Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK---RKEKEEEEKKRKRKRKKKK 70
Query: 400 EDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLR 459
E+ E R+ ++ ++ EE+ +E + EE R++++ +
Sbjct: 71 EE----EEREEEE-------EEEEEEKEEEEKEEGRRRKK-------------------K 100
Query: 460 RKRMEKMAEQQAVRERTRQLR 480
+KR K E++ ++R R+ +
Sbjct: 101 KKRRRKEEEEEKKKKRRRKTK 121
Score = 36.2 bits (82), Expect = 0.072
Identities = 23/108 (21%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 381 QKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEEC 440
+KK+++ E + +E E+ +E + ++ K+K +E+ K+++T+E K++E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR-----KEKRKEKEKKKKTKETEKRKE- 54
Query: 441 LFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
K E ++R K+ +++ E+ E++ E + E R ++
Sbjct: 55 ----KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98
Score = 29.6 bits (65), Expect = 6.8
Identities = 32/153 (20%), Positives = 59/153 (38%), Gaps = 30/153 (19%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHT 62
+ K K++EE E+ E + E E+ + E EK + + K ET E
Sbjct: 1 KKKKKKKKETEETEETEETE------EEEEKEGKRKEKRKEKRKEKEKKKKTKET--EKR 52
Query: 63 KRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEE 122
K + +K + + ++ + +E + E +++ EE+E+EE
Sbjct: 53 KEKEEEEKKRKRKRKKKKEE----------------------EEREEEEEEEEEEKEEEE 90
Query: 123 VRRYIMEKIVQANKLLQNQEPVNDKRERKLKFK 155
K + + + +E KR RK K K
Sbjct: 91 KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 29.3 bits (64), Expect = 8.8
Identities = 22/110 (20%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Query: 381 QKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKER--QTEELRKQE 438
+KK+++ E + +E E+ + ++ + KKK ++ ++R + EE +K++
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 439 ECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
K E RE ++ K E+ E + +++ ++ R E + K+
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
>gi|24307965 UBX domain containing 2 [Homo sapiens]
Length = 508
Score = 55.8 bits (133), Expect = 9e-08
Identities = 63/238 (26%), Positives = 107/238 (44%), Gaps = 33/238 (13%)
Query: 253 QQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPL-NRKTC---PSSAVNS 308
Q L +S S +G++ E S + T S++ EP N + C P+S S
Sbjct: 111 QMHLLKSETSVANGSQSESSVS-----TPSASFEPNNTCENSQSRNAELCEIPPTSDTKS 165
Query: 309 DRSKGNGKSNHRTQSAHISPVTS---TYCLSPRQKELQKQLEEKREKLKREEERRKIEEE 365
D + G + H T S S + L+ R + L K+LEE+RE+ ++EEE+R+I++E
Sbjct: 166 DTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKE 225
Query: 366 KEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQ 425
E+++ K L KR+Q E+ + + +E+ N + D R+
Sbjct: 226 IERRKTG----KEMLDYKRKQEEELTK----RMLEERNREKAEDRAARERI--------- 268
Query: 426 MKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQA-VRERTRQLRLE 482
+Q L + E F K E E A L K+ E ++++ RER+ R++
Sbjct: 269 ---KQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQ 323
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 55.5 bits (132), Expect = 1e-07
Identities = 40/164 (24%), Positives = 86/164 (52%), Gaps = 32/164 (19%)
Query: 340 KELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVL-----EMRR-- 392
+E +++++E+ EK++ +EE+ + +EEK +++E + K +++E+++ +MRR
Sbjct: 371 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 430
Query: 393 ------IQRAKEIED--------MNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQE 438
++ +E+E+ E R ++ R K++ +E RQ E++R+QE
Sbjct: 431 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 439 ECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLE 482
E + RE+ K W ++ EK+ EQ+ +RE ++ E
Sbjct: 491 EKI--------REQEEKMW---RQEEKIHEQEKIREEEKRQEQE 523
Score = 52.8 bits (125), Expect = 7e-07
Identities = 45/166 (27%), Positives = 88/166 (53%), Gaps = 23/166 (13%)
Query: 342 LQKQLEEK--REKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEI 399
L +Q EEK R++ K +E KI+E++EK RE + +K REQ +MRR +
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE-------EKIREQEEKMRRQE----- 402
Query: 400 EDMNSRENRDPQQAFRLWLKK---KHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQ 456
E M +E + +Q +W K+ + +E+M + E++R+ EE + +E+ +Q
Sbjct: 403 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM------HEQEKIREQ 456
Query: 457 WLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
+R+ EK+ EQ+ +E+ ++ + ++ ++ + + E K +R
Sbjct: 457 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502
Score = 52.4 bits (124), Expect = 1e-06
Identities = 39/172 (22%), Positives = 89/172 (51%), Gaps = 27/172 (15%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAK 397
+ + ++ + EK EK++R+EE +EEK ++ E +K EQ + ++ +
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE---------EKMHEQEKIREQEEKRQ 461
Query: 398 EIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLF----------FLKGT 447
E E + +E R Q+A ++W + EE+++E Q E++R+QEE ++ ++
Sbjct: 462 EEEKIREQEKRQEQEA-KMW---RQEEKIRE-QEEKIREQEEKMWRQEEKIHEQEKIREE 516
Query: 448 EGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
E R+ + W ++ EK+ EQ+ + + ++ + ++ ++ + ++ E K
Sbjct: 517 EKRQEQEEMW---RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Score = 52.0 bits (123), Expect = 1e-06
Identities = 50/227 (22%), Positives = 108/227 (47%), Gaps = 36/227 (15%)
Query: 296 LNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKR 355
L K + K + R Q + + +E ++++ E+ EK+ R
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502
Query: 356 EEER----RKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQ 411
+EE+ KI EE++++ + ++ W Q+ E++ E I R K E ++ +E + +
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEM----WRQE--EKIREQEEIWRQK--EKIHEQEEKIRK 554
Query: 412 QAFRLWLKKK----HEEQMKE------RQTEELRKQEECLFFLKGTEGRERAFKQ-WLRR 460
Q ++W +++ EE+++E RQ E++R+QEE K E E+ +Q + +
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE-----KIREQEEKIREQEEMTQ 609
Query: 461 KRMEKMAEQ--------QAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
++ EKM EQ + ++E+ ++R + ++ ++ + + E K
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Score = 52.0 bits (123), Expect = 1e-06
Identities = 53/196 (27%), Positives = 93/196 (47%), Gaps = 47/196 (23%)
Query: 338 RQKELQKQLEEK----REKLKREEERRKIEEEKEKKRENDIVFKAWLQ--KKREQVLEMR 391
RQKE + EEK EK+ R+EE+ +EEK +++E K W Q K REQ ++R
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE----KVWRQEEKIREQEEKIR 595
Query: 392 -RIQRAKEIEDMNSREN-----------------RDPQQAFRLWLKKKHEEQMKERQTEE 433
+ ++ +E E+M + ++ ++ R +K E++ K R+ EE
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 434 -LRKQEECLFFLKGTEGRERAFKQWLRRKRM----EKMAEQQAVRER------TRQLRLE 482
+R+QEE + +E+ K W + ++M EKM EQ+ R +++RL
Sbjct: 656 KIREQEEMM--------QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707
Query: 483 AKRSKQLQHHLYMSEA 498
+ K +H ++ A
Sbjct: 708 QQEEKMQEHQEHLEAA 723
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/175 (22%), Positives = 95/175 (54%), Gaps = 19/175 (10%)
Query: 338 RQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKR----EQVLEMRRI 393
RQ+E + E+ RE+ KR+E+ +E++ + + +I W QK++ E+ + +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI----WRQKEKIHEQEEKIRKQEE 557
Query: 394 QRAKEIEDMNSRENRDPQQAFRLWLK----KKHEEQMKERQTEELRKQEECLFFLKGTEG 449
+ ++ E M+ +E + +Q ++W + ++ EE+++E Q E++R+QEE + G
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE-QEEKIREQEEMTQEQEEKMG 616
Query: 450 RERAFKQWLRRKRMEKMAE-----QQAVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
E+ K + ++M++ E ++ +RE+ +++R + ++ ++ + + E K
Sbjct: 617 -EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 670
Score = 50.4 bits (119), Expect = 4e-06
Identities = 40/164 (24%), Positives = 87/164 (53%), Gaps = 11/164 (6%)
Query: 339 QKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKE 398
Q+E+ +Q E+ RE+ + ++ KI E++EK R+ + K W Q+++ E +I+ +E
Sbjct: 522 QEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE--EKMWRQEEKMHDQE-EKIREQEE 578
Query: 399 IEDMNSRENRDPQQAFRLWLKK-KHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQW 457
+ R+ ++ R +K + +E+M + Q E++ +QEE K E E+ +Q
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE-----KMCEQEEKMQEQE 633
Query: 458 LRRKRMEKMAEQQ--AVRERTRQLRLEAKRSKQLQHHLYMSEAK 499
+ +R E+ +Q +RE+ ++R + + ++ + ++ E K
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Score = 46.6 bits (109), Expect = 5e-05
Identities = 39/177 (22%), Positives = 83/177 (46%), Gaps = 28/177 (15%)
Query: 335 LSPRQKELQKQLEEKREKLKREEERRKI-----EEEKEKKRENDIVFKAWLQKKREQVLE 389
L L K+L+ KL+ + E ++ ++++EK + + W +K +EQ +
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
Query: 390 MRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEG 449
+R ++ ++I + + R + + K + +E+M + E++R+QEE +
Sbjct: 384 IR--EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM-------- 433
Query: 450 RERAFKQWLRRKRM----EKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFR 502
W + +++ EKM EQ+ +RE+ + + E K +Q + EAK +R
Sbjct: 434 -------WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ--EQEAKMWR 481
Score = 36.2 bits (82), Expect = 0.072
Identities = 39/205 (19%), Positives = 87/205 (42%), Gaps = 30/205 (14%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASII---EMACEKEENINQDLKENETVM 59
E K + +K E E E++ W E + I E E+EE I + +E +
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK--QEEKMWR 561
Query: 60 EHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEE 119
+ K H +K + E R + + I + + + QE K+ Q+++ +E+
Sbjct: 562 QEEKMHDQEEKIREQEEKVWRQE----------EKIREQEEKIREQEEKIREQEEMTQEQ 611
Query: 120 DEEVRRYIM------EKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFK 173
+E++ EK+ + + ++ QE ++E+K++ +++ + + ++
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ------ 665
Query: 174 NYFENERNMFGKLSQLCISNDFGQE 198
E E M+ + ++C + QE
Sbjct: 666 ---EQEEKMWEQEEKMCEQEEKMQE 687
Score = 35.8 bits (81), Expect = 0.095
Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 12/147 (8%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHT 62
E K + ++ +++ ++ E + E E+ E CE+EE + + + E +
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE---QEEKMRRQE 640
Query: 63 KRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEE 122
++ + +K ++++ R + + + + + + QE K+ Q++ +E++E+
Sbjct: 641 EKIREQEKKIREQEEKIR---------EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Query: 123 VRRYIMEKIVQANKLLQNQEPVNDKRE 149
+RR + Q +L Q +E + + +E
Sbjct: 692 MRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 29.6 bits (65), Expect = 6.8
Identities = 28/155 (18%), Positives = 68/155 (43%), Gaps = 27/155 (17%)
Query: 3 ENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHT 62
E K + ++ +++ ++ E I E E+ EM E+EE + + +
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE---------QEE 620
Query: 63 KRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEE 122
K +K + E RR + + I + + + QE K+ Q+++ +E++E+
Sbjct: 621 KMCEQEEKMQEQEEKMRRQE----------EKIREQEKKIREQEEKIREQEEMMQEQEEK 670
Query: 123 VRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQ 157
+ Q K+ + +E + ++ E K++ +++
Sbjct: 671 MWE-------QEEKMCEQEEKMQEQEE-KMRRQEE 697
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 55.1 bits (131), Expect = 2e-07
Identities = 78/389 (20%), Positives = 161/389 (41%), Gaps = 45/389 (11%)
Query: 119 EDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFEN 178
E EE + ++ + KL Q+ E V + E K K +L +++T ++
Sbjct: 331 ELEENKELAQNRLCELEKLRQDFEEVTTQNE---KLKVELRSAVEQVVKETPEYRCMQSQ 387
Query: 179 ERNMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDG-------KFELLNLQ 231
++ + QL D + +L +G+ ++ + L+ERD + E++ L+
Sbjct: 388 FSVLYNESLQLKAHLDEAR-----TLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLE 442
Query: 232 DIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYI 291
D +Q + +Q L + + + + + H GE L Y
Sbjct: 443 DTLAQ----VRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYK 498
Query: 292 -----AQPPLN--RKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQK 344
AQ LN R S+ + S S + K ++S S +E
Sbjct: 499 RKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDAN 558
Query: 345 QLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNS 404
+++ KR++ +RE ERR+ E E+E++RE K++E+ E ++++ +++ D
Sbjct: 559 EIKSKRDEEERERERREKERERERERE----------KEKEREREKQKLKESEKERDSAK 608
Query: 405 RENRDPQQAFRLWLKKKHEEQMKE-----RQTEELRKQEECLFFLKGTEGRERAFKQWLR 459
+ + R KK E +K+ ++ +E +K+ + L + + +E+ K L
Sbjct: 609 DKEKGKHDDGR----KKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLM 664
Query: 460 RKRMEKMAEQQAVRERTRQLRLEAKRSKQ 488
+ AE + +R+R + L + K+ +
Sbjct: 665 AAEKKSKAELEDLRQRLKDLEDKEKKENK 693
Score = 39.7 bits (91), Expect = 0.007
Identities = 40/172 (23%), Positives = 85/172 (49%), Gaps = 15/172 (8%)
Query: 333 YCLSPRQKELQKQL--EEKREKLKREEERRKIE--EEKEKKRENDIVFKAWLQKKR--EQ 386
Y +P+++ + QL EK+ K + E+ R++++ E+KEKK + + L+K R E+
Sbjct: 650 YRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEE 709
Query: 387 VLE--MRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFL 444
+E +++ AK+ E+ E QAF + ++ R ++LR++++ F L
Sbjct: 710 QIEYLQKKLAMAKQEEEALLSEMDVTGQAF------EDMQEQNIRLMQQLREKDDANFKL 763
Query: 445 KGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMS 496
+ + L+ ++ E++A+Q + +L+ R + + HL S
Sbjct: 764 MSERIKSNQIHKLLKEEK-EELADQVLTLKTQVDAQLQVVRKLEEKEHLLQS 814
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 55.1 bits (131), Expect = 2e-07
Identities = 60/236 (25%), Positives = 105/236 (44%), Gaps = 20/236 (8%)
Query: 267 TKKEDSTAKIHAVTH--SSTGEPLAYIAQPPLNRKTCPSSAVNS--DRSKGNGKSNHRTQ 322
T KE+ IH + S E +A+PP +S V D +K + +
Sbjct: 256 TLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLE 315
Query: 323 SAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEK-----EKKRENDIVFK 377
S V + LS KE +++L+E+ E L+ +E +R E+E+ E+ RE +
Sbjct: 316 GKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQ 375
Query: 378 AWLQKKREQVLEMRRIQRA--KEIEDMNSRENRDPQQAFRLWLK----KKHEEQMKERQT 431
++ R+Q +R+ + KE E + +E R Q RLW K +K EE++ Q
Sbjct: 376 EQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQN 435
Query: 432 EELRKQ---EECLFFLKGTEGRERAFKQWLRRKRMEKMAEQ--QAVRERTRQLRLE 482
+L KQ +C F E + + ++ EK+ E+ +A ++ +QL +
Sbjct: 436 HKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQ 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,308,901
Number of Sequences: 37866
Number of extensions: 1031509
Number of successful extensions: 21722
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 387
Number of HSP's successfully gapped in prelim test: 1002
Number of HSP's that attempted gapping in prelim test: 8636
Number of HSP's gapped (non-prelim): 7198
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.