Guide to the Human Genome
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Search of human proteins with 4557743

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557743 Mediterranean fever protein [Homo sapiens]
         (781 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557743 Mediterranean fever protein [Homo sapiens]                1580   0.0  
gi|5730009 ret finger protein [Homo sapiens]                          350   4e-96
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   258   2e-68
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   257   3e-68
gi|15208660 tripartite motif protein 21 [Homo sapiens]                253   5e-67
gi|37622899 ring finger protein 137 [Homo sapiens]                    230   3e-60
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             226   5e-59
gi|63054855 erythroblast membrane-associated protein precursor [...   216   5e-56
gi|19923536 erythroblast membrane-associated protein precursor [...   216   5e-56
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            213   7e-55
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    203   4e-52
gi|149193331 tripartite motif protein 15 [Homo sapiens]               201   2e-51
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    199   1e-50
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    199   1e-50
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              197   4e-50
gi|22749269 ring finger protein 129 [Homo sapiens]                    192   1e-48
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            191   2e-48
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             191   3e-48
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   189   8e-48
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]      174   2e-43
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   174   3e-43
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      171   2e-42
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      171   2e-42
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   171   2e-42
gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo...   169   9e-42
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...   169   9e-42
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   168   2e-41
gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]   168   2e-41
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ...   167   3e-41
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo...   167   3e-41

>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score = 1580 bits (4091), Expect = 0.0
 Identities = 781/781 (100%), Positives = 781/781 (100%)

Query: 1   MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY 60
           MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
Sbjct: 1   MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY 60

Query: 61  YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT 120
           YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
Sbjct: 61  YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT 120

Query: 121 PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP 180
           PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP
Sbjct: 121 PDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSP 180

Query: 181 ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP 240
           ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP
Sbjct: 181 ALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRP 240

Query: 241 RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH 300
           RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH
Sbjct: 241 RSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEH 300

Query: 301 SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE 360
           SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE
Sbjct: 301 SVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHE 360

Query: 361 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK 420
           RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK
Sbjct: 361 RKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHK 420

Query: 421 KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF 480
           KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF
Sbjct: 421 KKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF 480

Query: 481 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT 540
           VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT
Sbjct: 481 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT 540

Query: 541 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV 600
           VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV
Sbjct: 541 VPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNV 600

Query: 601 ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG 660
           ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG
Sbjct: 601 ILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVG 660

Query: 661 DKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGI 720
           DKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGI
Sbjct: 661 DKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGI 720

Query: 721 FVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGP 780
           FVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGP
Sbjct: 721 FVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGP 780

Query: 781 D 781
           D
Sbjct: 781 D 781


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  350 bits (897), Expect = 4e-96
 Identities = 173/403 (42%), Positives = 265/403 (65%), Gaps = 4/403 (0%)

Query: 375 CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLR 434
           C++H + ++L +CE+   PIC++C  S+EH+GH V P+EE     K++IQ QL+HLK+++
Sbjct: 96  CEKHREPLKL-YCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVK 154

Query: 435 KSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQI 494
              + +R+ GE+     L  T+  ++++  + EQ+Y+ L++ E+  +A LE++   +   
Sbjct: 155 DLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNS 214

Query: 495 RKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIK 554
                T+ S +I+ L +LI +LE K+ Q   ELLQDIGD L RA+ + +PE W TP +++
Sbjct: 215 INGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQ 274

Query: 555 QKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFS 614
           +KI +  QK  F+ +S K F+E ++S+ME   + EL  AQ ++V+V LD +TAYP+LI S
Sbjct: 275 EKIHIFAQKCLFLTESLKQFTEKMQSDME--KIQELREAQLYSVDVTLDPDTAYPSLILS 332

Query: 615 DDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSI 674
           D+L+ VR     + LPD P+RF+    VLGSP F++GR YWEVEVGDK  W +G C+ S+
Sbjct: 333 DNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSV 392

Query: 675 SRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNV 734
            RKG +T +P+NG+W V +    EY A + P T L ++ P +RVGIF+DY  G +SFYNV
Sbjct: 393 CRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNV 452

Query: 735 TARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGG 777
           T R H +TF+  +F GP++P FS  +  GGK+ APL ICP+ G
Sbjct: 453 TERCHTFTFSHATFCGPVRPYFSL-SYSGGKSAAPLIICPMSG 494


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  258 bits (658), Expect = 2e-68
 Identities = 154/413 (37%), Positives = 236/413 (57%), Gaps = 19/413 (4%)

Query: 375 CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLR 434
           C +H + + L FC +  E +CLIC++S  H+ H V P+++   E+K+K+QK LE L++  
Sbjct: 107 CPQHHEALSL-FCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKL 165

Query: 435 KSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQI 494
           +     +S  E+K     +  E+ +Q++ R+ E+++  L++++   ++ LE+  Q + Q 
Sbjct: 166 QEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQR 225

Query: 495 RKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKW------T 548
            +     +      L  L  E+E K  QS +E+L+D+   L +     +P K+       
Sbjct: 226 LRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKN----IPRKFGGSLSTI 281

Query: 549 TPQEIKQKIQLLHQKSEFVE-KSTKYFSETLRSEMEMFNVPELIGAQAHAV-----NVIL 602
            P++ K  + L+ + +   + K+ +  S ++  E    N P    A    +     +V L
Sbjct: 282 CPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTL 341

Query: 603 DAETAYPNLIFSDDLKSVR-LGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGD 661
           D ETA+PNL+ S+D KSV+ +  +   LPD P+RF     VL +  F SGR YWEVEVGD
Sbjct: 342 DPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGD 401

Query: 662 KTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIF 721
           KT W +G C+ S+SRKG +T  PE GYW V +   ++Y A++ P T L IK  PKRVGIF
Sbjct: 402 KTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIF 461

Query: 722 VDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICP 774
           +DY  G++SFYNVT RSHIYTF   +F+  L P+F PG R G KN APLTI P
Sbjct: 462 LDYEAGTLSFYNVTDRSHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRP 513


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  257 bits (657), Expect = 3e-68
 Identities = 151/401 (37%), Positives = 228/401 (56%), Gaps = 25/401 (6%)

Query: 375 CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLR 434
           C +H + + L FC +  E +CLIC++S  H+ H V P+++   E+K+K+QK LE L++  
Sbjct: 107 CPQHHEALSL-FCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKL 165

Query: 435 KSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQI 494
           +     +S  E+K     +  E+ +Q++ R+ E+++  L++++   ++ LE+  Q + Q 
Sbjct: 166 QEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQR 225

Query: 495 RKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIK 554
            +     +      L  L  E+E K  QS +E+L+D+   L + + V   E  +   E++
Sbjct: 226 LRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELE 285

Query: 555 QKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFS 614
           +          F     +YF+  LR  ++               +V LD ETA+PNL+ S
Sbjct: 286 KN---------FSNFPRQYFA--LRKILKQL-----------IADVTLDPETAHPNLVLS 323

Query: 615 DDLKSVR-LGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTS 673
           +D KSV+ +  +   LPD P+RF     VL +  F SGR YWEVEVGDKT W +G C+ S
Sbjct: 324 EDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDS 383

Query: 674 ISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYN 733
           +SRKG +T  PE GYW V +   ++Y A++ P T L IK  PKRVGIF+DY  G++SFYN
Sbjct: 384 VSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYN 443

Query: 734 VTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICP 774
           VT RSHIYTF   +F+  L P+F PG R G KN APLTI P
Sbjct: 444 VTDRSHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRP 483


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  253 bits (646), Expect = 5e-67
 Identities = 146/409 (35%), Positives = 230/409 (56%), Gaps = 31/409 (7%)

Query: 374 QCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKL 433
           +C  H +++ L FCE   + +C +C+ S++H+ H + P+EE A E+++K+Q  L  L++ 
Sbjct: 91  RCAVHGERLHL-FCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRK 149

Query: 434 RKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQ 493
           ++  E+       K   + K  E  K R+  +  Q   FL ++E   +  LE   +   +
Sbjct: 150 QELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLR 209

Query: 494 IRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEI 553
           I    + +++Q    L  LI EL+ +   S  ELLQ++  +L R+      E W      
Sbjct: 210 ILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERS------ESWNL---- 259

Query: 554 KQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIF 613
                          K     S  LRS   +  + +++  +  AV++ LD +TA P LI 
Sbjct: 260 ---------------KDLDITSPELRSVCHVPGLKKML--RTCAVHITLDPDTANPWLIL 302

Query: 614 SDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTS 673
           S+D + VRLG+  + +P   +RFDS  +VLG+  F SG+ YWEV+V  K AW LG C+ S
Sbjct: 303 SEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDS 362

Query: 674 ISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYN 733
           + RKG+  LS ++G+W + +  + +Y+A + P T L ++ PP +VGIF+DY  G +SFYN
Sbjct: 363 VRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYN 422

Query: 734 VTAR-SHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICP--VGGQG 779
           +T   S IY+F+ C+F+GPL+P FSPG  DGGKNTAPLT+CP  +G QG
Sbjct: 423 ITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQG 471


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  230 bits (587), Expect = 3e-60
 Identities = 146/415 (35%), Positives = 224/415 (53%), Gaps = 39/415 (9%)

Query: 375 CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLR 434
           C+RH +++++ FC++    +C  CS S EH+ H V P+E+VA E+K ++ + LEHLKK +
Sbjct: 98  CERHGEKLKM-FCKEDVLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQ 156

Query: 435 KSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEH----------FFVASL 484
           +   +      ++  ++  Q E  KQ +  + E+    LE+++             +ASL
Sbjct: 157 EEAWKLEVGERKRTATWKIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASL 216

Query: 485 EDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVP 544
           +       Q  +   + + Q   +L  +I EL+ +  +    +LQDI ++L+R+K+    
Sbjct: 217 QREAAETMQKLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKS---- 272

Query: 545 EKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDA 604
             W+  Q                    +  S  L+++  +  + E++  + +A +V LD 
Sbjct: 273 --WSLQQP-------------------EPISLELKTDCRVLGLREIL--KTYAADVRLDP 309

Query: 605 ETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTA 664
           +TAY  LI S+D K V  G+  ++LPD P+RF    IVLGS    SGR YWEVEVGD++ 
Sbjct: 310 DTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSE 369

Query: 665 WILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDY 724
           W LG CK ++ RK  + LSP  G+WV+ + K NEY+A +     L +  PP+RVGIFVDY
Sbjct: 370 WGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDY 429

Query: 725 RVGSISFYNVT-ARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQ 778
               ISFYNVT   SHI+TF    F G L P FSP    G  NTAPL IC + G+
Sbjct: 430 EAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYSIGTNNTAPLAICSLDGE 484


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  226 bits (577), Expect = 5e-59
 Identities = 144/416 (34%), Positives = 213/416 (51%), Gaps = 42/416 (10%)

Query: 369 PQPLPQ--CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQ 426
           P P+PQ  C  H ++    FC D    +C  C  S EH  HRVRP+++ A + K K++K 
Sbjct: 84  PSPVPQGVCPAH-REPLAAFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKS 142

Query: 427 LEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLED 486
           LEHL+K  +     ++  +E  V + K  E+ +Q V  + E++   L ++E   +  LE+
Sbjct: 143 LEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEE 202

Query: 487 VGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEK 546
               V    +     + Q  A L  LI ELE +       LLQDI D L R + V +   
Sbjct: 203 EELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQPP 262

Query: 547 WTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAET 606
              P E++   ++                ETLR                   +V LD +T
Sbjct: 263 EVVPMELRTVCRV------------PGLVETLRR---------------FRGDVTLDPDT 295

Query: 607 AYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWI 666
           A P LI S+D +SV+ G+  + LPD P+RFD    VLG   F SGR YWEVEVGD+T+W 
Sbjct: 296 ANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWA 355

Query: 667 LGACKTSISRKGNMTLSPENGYWVVIMMKE--NEYQASSVPPTRLLIKEPPKRVGIFVDY 724
           LG C+ +++RK    LS  NG+W+++ +    N  + +  P     +++PP+RVGIF+DY
Sbjct: 356 LGVCRENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAP-----LRDPPRRVGIFLDY 410

Query: 725 RVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTIC-PVGGQG 779
             G +SFY+ T  S ++ F    FSG L+P+FSP +     +  P+TIC P GG G
Sbjct: 411 EAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLS----SSPTPMTICRPKGGSG 462


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  216 bits (551), Expect = 5e-56
 Identities = 107/199 (53%), Positives = 137/199 (68%), Gaps = 4/199 (2%)

Query: 578 LRSEMEMFNVPELIG---AQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQ 634
           LRSE+++       G   A+ H V V LD +TA+P LI S+D + VRLG++ + +PD PQ
Sbjct: 215 LRSELKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQ 274

Query: 635 RFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMM 694
           RFD  + +LGS  F +G  YWEV VGDKT WILG C  S+SRKG +T SP NG+W++   
Sbjct: 275 RFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQS 334

Query: 695 KENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQP 754
           + NEY+A + P T   +KEPP+ VGIF+DY  G ISFYNVT +SHI+TF   +FSGPL+P
Sbjct: 335 RGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTH-NFSGPLRP 393

Query: 755 IFSPGTRDGGKNTAPLTIC 773
            F P   DGGKNTAPL IC
Sbjct: 394 FFEPCLHDGGKNTAPLVIC 412


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  216 bits (551), Expect = 5e-56
 Identities = 107/199 (53%), Positives = 137/199 (68%), Gaps = 4/199 (2%)

Query: 578 LRSEMEMFNVPELIG---AQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQ 634
           LRSE+++       G   A+ H V V LD +TA+P LI S+D + VRLG++ + +PD PQ
Sbjct: 215 LRSELKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQ 274

Query: 635 RFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMM 694
           RFD  + +LGS  F +G  YWEV VGDKT WILG C  S+SRKG +T SP NG+W++   
Sbjct: 275 RFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQS 334

Query: 695 KENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQP 754
           + NEY+A + P T   +KEPP+ VGIF+DY  G ISFYNVT +SHI+TF   +FSGPL+P
Sbjct: 335 RGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTH-NFSGPLRP 393

Query: 755 IFSPGTRDGGKNTAPLTIC 773
            F P   DGGKNTAPL IC
Sbjct: 394 FFEPCLHDGGKNTAPLVIC 412


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  213 bits (541), Expect = 7e-55
 Identities = 132/383 (34%), Positives = 199/383 (51%), Gaps = 29/383 (7%)

Query: 374 QCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKL 433
           +C RH + +   FCE+ +  +C +C    EH+ HR  P++E A  ++ K+Q  LE ++K 
Sbjct: 95  RCARHGEDLSR-FCEEDEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKE 153

Query: 434 RKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQ 493
            +    Q +   +K V + ++ E  +QR + + E+   FL Q+E   +  LE   +   Q
Sbjct: 154 LEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQ 213

Query: 494 IRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEI 553
             +   +R+ Q    L  L  EL+ +  +    LL+ +  +L R+K V   E    P E+
Sbjct: 214 RLRESKSRLVQQSKALKELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMEL 273

Query: 554 KQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIF 613
           K    +  ++            E LR                  V+V LD  TA+P+L+ 
Sbjct: 274 KTACCIPGRR------------ELLRK---------------FQVDVKLDPATAHPSLLL 306

Query: 614 SDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTS 673
           + DL+SV+ G  W  +P+ P+RFD+   +LG  SF SGR YWEV VG+   W LG C+ +
Sbjct: 307 TADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDT 366

Query: 674 ISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYN 733
           + RKG  T SPENG W + ++K NEY   + P   LL  E P+ +GIF+DY  G ISFYN
Sbjct: 367 LPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYN 426

Query: 734 VTARSHIYTFASCSFSGPLQPIF 756
           VT  S+IYTF    FSG L+P F
Sbjct: 427 VTDGSYIYTFNQL-FSGLLRPYF 448


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  203 bits (517), Expect = 4e-52
 Identities = 127/398 (31%), Positives = 204/398 (51%), Gaps = 13/398 (3%)

Query: 360 ERKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEH 419
           E  S  + +     +C +H +  +L +C+D    IC++C  ++EH+ H V P++E   E 
Sbjct: 115 EHGSQAAAARAAAARCGQHGEPFKL-YCQDDGRAICVVCDRAREHREHAVLPLDEAVQEA 173

Query: 420 KKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHF 479
           K+ ++ +L  LKK  +  E  RS  ++++   LKQ  A +++V  + + +  FL +QE  
Sbjct: 174 KELLESRLRVLKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGR 233

Query: 480 FVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAK 539
            +  LE++ + V Q +     ++  +I  L  L  +++    + + + LQ+    L R  
Sbjct: 234 LLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCS 293

Query: 540 TVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVN 599
            VP P+  T   E+K K+  +  K+  ++   K F E LR E+E          +   V 
Sbjct: 294 NVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELE----------KEEKVE 343

Query: 600 VILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEV 659
           + LD +TA P LI S DLK VRLG + + LP+ P RFD+   VL S  F SGR +WEVEV
Sbjct: 344 LTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEV 403

Query: 660 GDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVG 719
           G K  W  G  + S+ RKG    +PE G W  + +   +Y A + P    L      RV 
Sbjct: 404 GSKDGWAFGVARESVRRKGLTPFTPEEGVW-ALQLNGGQYWAVTSPERSPLSCGHLSRVR 462

Query: 720 IFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFS 757
           + +D  VG++SFY V    H+YTF   +F   + P+FS
Sbjct: 463 VALDLEVGAVSFYAVEDMRHLYTF-RVNFQERVFPLFS 499


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  201 bits (512), Expect = 2e-51
 Identities = 137/425 (32%), Positives = 219/425 (51%), Gaps = 31/425 (7%)

Query: 346 GSRSPG----CPRCQDSHERKSPGSLSPQPL-----PQCKRHLKQVQLLFCEDHDEPICL 396
           G++S G    CP CQ+  + ++P  ++P PL       C+ H +++   FCE+  E +C+
Sbjct: 47  GAQSSGKILLCPLCQEEEQAETP--MAPVPLGPLGETYCEEHGEKIYF-FCENDAEFLCV 103

Query: 397 ICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTE 456
            C     HQ H V  ++E    ++ +++ +LE L   R   E+ +   ++K    L Q E
Sbjct: 104 FCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIE 163

Query: 457 ALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGEL 516
           + K +V+   E++   LEQQ    +A L ++ Q + + R  Y T+VS+++  L A + EL
Sbjct: 164 SKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKEL 223

Query: 517 EAKECQSEWELLQDIGDILHRA--KTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYF 574
           E K  Q   ELLQD+     R   KT   PE      ++ +KI+  H+K   + +  + F
Sbjct: 224 EEKCQQPASELLQDVRVNQSRCEMKTFVSPE--AISPDLVKKIRDFHRKILTLPEMMRMF 281

Query: 575 SETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQ 634
           SE L   +E+            +  + LD +TA  +L+ S+D KSVR   + + LPD P 
Sbjct: 282 SENLAHHLEI-----------DSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPL 330

Query: 635 RFDSCIIVLGSPSFLSGRRYWEV--EVGDKTAWILGACKTSISRKGNMTLSPENGYWVVI 692
           RFD    VLG P F SGR  W+V  ++GD     +G     + RKG M LS E+G W VI
Sbjct: 331 RFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVI 390

Query: 693 MMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPL 752
            +   +  AS+ P T L + E P+ V + +DY  G ++ +N   +  I+TF + SFSG +
Sbjct: 391 -ISHQQCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTF-TASFSGKV 448

Query: 753 QPIFS 757
            P F+
Sbjct: 449 FPFFA 453


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  199 bits (505), Expect = 1e-50
 Identities = 149/483 (30%), Positives = 223/483 (46%), Gaps = 61/483 (12%)

Query: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSP-GCPRCQDSHERKSPGSLSP-Q 370
           P C     +P+   C    C      +G     G      CP CQ S++   PG+L P +
Sbjct: 16  PICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ---PGNLRPNR 72

Query: 371 PLPQCKRHLKQVQL-------------------LFCEDHDEPICLICSLSQEHQGHRVRP 411
            L    R L++V L                   LFC++  + IC +C  SQEH+GH    
Sbjct: 73  HLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFL 132

Query: 412 IEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYY 471
           +EEVA E+++K Q+ L+ LK   +  E+  ++  EK  S+  Q E  + R+Q +  Q+  
Sbjct: 133 VEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRN 192

Query: 472 FLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531
            L++ E   +  LE   +   +I +  +  +      L  LI +LE +   S  ELLQD+
Sbjct: 193 ILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDV 252

Query: 532 GDILHRAKTVPVPEKWT--TPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPE 589
            D+  R+      E WT   P+ +  K+     +S F     K      R         E
Sbjct: 253 SDVTERS------EFWTLRKPEALPTKL-----RSMFRAPDLKRMLRVCR---------E 292

Query: 590 LIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFL 649
           L   Q++ V+V L+  TA  NL+ + + + VR        P   ++   C  VLGS  F 
Sbjct: 293 LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC-SVLGSQHFS 351

Query: 650 SGRRYWEVEVGDKTAWILGACKTSI-----------SRKGNMTLSPENGYWVVIMMKENE 698
           SG+ YWEV+V  KTAWILG C  S+           +        P++GYWV+ +   +E
Sbjct: 352 SGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 411

Query: 699 YQA--SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSH-IYTFASCSFSGPLQPI 755
           Y+A   S P   L +  PP+RVG+F+DY  G++SFYNVT     IYTF+   F   L P 
Sbjct: 412 YRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPY 471

Query: 756 FSP 758
           F+P
Sbjct: 472 FNP 474


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  199 bits (505), Expect = 1e-50
 Identities = 149/483 (30%), Positives = 223/483 (46%), Gaps = 61/483 (12%)

Query: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSP-GCPRCQDSHERKSPGSLSP-Q 370
           P C     +P+   C    C      +G     G      CP CQ S++   PG+L P +
Sbjct: 44  PICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ---PGNLRPNR 100

Query: 371 PLPQCKRHLKQVQL-------------------LFCEDHDEPICLICSLSQEHQGHRVRP 411
            L    R L++V L                   LFC++  + IC +C  SQEH+GH    
Sbjct: 101 HLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFL 160

Query: 412 IEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYY 471
           +EEVA E+++K Q+ L+ LK   +  E+  ++  EK  S+  Q E  + R+Q +  Q+  
Sbjct: 161 VEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRN 220

Query: 472 FLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531
            L++ E   +  LE   +   +I +  +  +      L  LI +LE +   S  ELLQD+
Sbjct: 221 ILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDV 280

Query: 532 GDILHRAKTVPVPEKWT--TPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPE 589
            D+  R+      E WT   P+ +  K+     +S F     K      R         E
Sbjct: 281 SDVTERS------EFWTLRKPEALPTKL-----RSMFRAPDLKRMLRVCR---------E 320

Query: 590 LIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFL 649
           L   Q++ V+V L+  TA  NL+ + + + VR        P   ++   C  VLGS  F 
Sbjct: 321 LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC-SVLGSQHFS 379

Query: 650 SGRRYWEVEVGDKTAWILGACKTSI-----------SRKGNMTLSPENGYWVVIMMKENE 698
           SG+ YWEV+V  KTAWILG C  S+           +        P++GYWV+ +   +E
Sbjct: 380 SGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 439

Query: 699 YQA--SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSH-IYTFASCSFSGPLQPI 755
           Y+A   S P   L +  PP+RVG+F+DY  G++SFYNVT     IYTF+   F   L P 
Sbjct: 440 YRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPY 499

Query: 756 FSP 758
           F+P
Sbjct: 500 FNP 502


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  197 bits (500), Expect = 4e-50
 Identities = 131/417 (31%), Positives = 208/417 (49%), Gaps = 37/417 (8%)

Query: 352 CPRCQ-----DS-HERKSPGSL------SPQPLPQCKRHLKQVQLLFCEDHDEPICLICS 399
           CP+C+     DS    K  GSL      + Q +  C+ H +Q  L FCED  + IC  C 
Sbjct: 59  CPQCRAPFHMDSLRPNKQLGSLIEALKETDQEM-SCEEHGEQFHL-FCEDEGQLICWRCE 116

Query: 400 LSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALK 459
            + +H+GH    +E+V   +K+K+QK +  LK+L     EQ+     +   + ++ +  +
Sbjct: 117 RAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQR 176

Query: 460 QRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAK 519
           Q+++   + +  FL ++E  ++  LE   Q      + Y+  +      L + I ELE K
Sbjct: 177 QKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEK 236

Query: 520 ECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLR 579
              S  +LLQ++ D L R+  V    K  T + +  ++  +   S+              
Sbjct: 237 CQGSAQKLLQNVNDTLSRSWAV----KLETSEAVSLELHTMCNVSKLY------------ 280

Query: 580 SEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSC 639
                F+V +++  ++H V+V LD +TA+  LI S+D + V  G   E      +RF + 
Sbjct: 281 -----FDVKKML--RSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAF 333

Query: 640 IIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEY 699
             VLG   F SGRRY+EV+VG+ T W LG C  ++ R   M   P++G+W + + K+  Y
Sbjct: 334 PCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGY 393

Query: 700 QASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIF 756
            A + PPT L + E P  VGIF+DY  G +SFYN     HI+TF   SFS  L+P F
Sbjct: 394 VALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  192 bits (487), Expect = 1e-48
 Identities = 128/406 (31%), Positives = 195/406 (48%), Gaps = 41/406 (10%)

Query: 375 CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLR 434
           C++H  Q   LFC    E +C  CS S +HQ H + PI++ A  H++ ++  LE L+   
Sbjct: 97  CEKH-NQFLTLFCVKDLEILCTQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNI 155

Query: 435 KSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQI 494
           +  E+       K+V   K+ E  ++ +  + EQ+  FL+ ++   +  ++D    +   
Sbjct: 156 ERVEKVIILQGSKSVELKKKVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAK 215

Query: 495 RKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIK 554
                  +S  ++ L  L+ E+E K  QS  ELL     + H+ + +  PE         
Sbjct: 216 LNENLVELSDYVSTLKHLLREVEGKSVQSNLELLTQAKSMHHKYQNLKCPEL-------- 267

Query: 555 QKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGA-----QAHAVNVILDAETAYP 609
                      F  + TKY           F++P          +   V+VILD  TA+P
Sbjct: 268 -----------FSFRLTKYG----------FSLPPQYSGLDRIIKPFQVDVILDLNTAHP 306

Query: 610 NLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGA 669
            L+ S+D K+VR   K   +   P+RF  C  VLGS  F SGR YWEVEVG+K  WILG 
Sbjct: 307 QLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGV 366

Query: 670 CKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSI 729
           C+  + R      S   G+W +    ++ Y AS    T+LL    P ++GIF+DY +G +
Sbjct: 367 CQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDL 426

Query: 730 SFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPV 775
           SFYN+  RS +YTF  C F+  + P F  GT     ++ PL IC V
Sbjct: 427 SFYNMNDRSILYTFNDC-FTEAVWPYFYTGT-----DSEPLKICSV 466


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  191 bits (486), Expect = 2e-48
 Identities = 126/405 (31%), Positives = 201/405 (49%), Gaps = 43/405 (10%)

Query: 380 KQVQLLFCEDHDEPI-----------CLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLE 428
           KQ +   CE H++P+           C +C+   +HQGH VRPIE+ A+ ++K+    ++
Sbjct: 90  KQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQ 149

Query: 429 HLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVG 488
            LKK     ++  S   +K +   +  E  +Q +  + E +  FL++++   ++ L +  
Sbjct: 150 PLKKQLADLQKLISTQSKKPLELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEE 209

Query: 489 QMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWT 548
           +   Q   A  T  S   A L + + ++      SE ELL  I               + 
Sbjct: 210 KDNQQKLSANITAFSNYSATLKSQLSKVVELSELSELELLSQIKIF------------YE 257

Query: 549 TPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAY 608
           +  E    I  +H K +      +Y    L+  ++ F V            +ILD ETA+
Sbjct: 258 SENESSPSIFSIHLKRDGCSFPPQY--SALQRIIKKFKV-----------EIILDPETAH 304

Query: 609 PNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILG 668
           PNLI S+D K VR   + +++P  P+RF    +VLG P F SGR +WE+EVGDK+ W +G
Sbjct: 305 PNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIG 364

Query: 669 ACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGS 728
            CK S+  K     S +   W  I ++++ Y A    PT LL++   + +GIF+DY +G 
Sbjct: 365 ICKDSLPTKARRPSSAQQECW-RIELQDDGYHAPGAFPTPLLLEVKARAIGIFLDYEMGE 423

Query: 729 ISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTIC 773
           ISFYN+  +SHI TF   +F+GPL+P F       G ++ PL IC
Sbjct: 424 ISFYNMAEKSHICTFTD-TFTGPLRPYFYV-----GPDSQPLRIC 462


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  191 bits (484), Expect = 3e-48
 Identities = 119/377 (31%), Positives = 195/377 (51%), Gaps = 33/377 (8%)

Query: 400 LSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALK 459
           ++Q H  +RV    E    H++K+Q+ L  L+  RK  +   ++ +E+     ++T+  K
Sbjct: 116 VAQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCK 175

Query: 460 QRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAK 519
           Q V  +  +++ FL+++E   +  LE   +   +  +  + +++Q I  L  +I ++E+ 
Sbjct: 176 QVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESS 235

Query: 520 ECQSEWELLQDIGDILHRAKTVPV--PEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSET 577
              S +E L+++   L R++ + +  PE  TT   + +   +     +F           
Sbjct: 236 SQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITGMKEMLRKF----------- 284

Query: 578 LRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFD 637
                              +  + LD  TA   L+ S+DLKSV+ G   ++LPD P+RFD
Sbjct: 285 -------------------STEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFD 325

Query: 638 SCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKEN 697
               VLG+  F SGR YWEVEVG+KT W +G CK S+SRKGN+   P + + ++ +   +
Sbjct: 326 QSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGD 385

Query: 698 EYQA-SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIF 756
           +Y    S P     ++EP  +VG+F+DY  G I+FYN T  S IY+F   SF   L+PIF
Sbjct: 386 DYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIF 445

Query: 757 SPGTRDGGKNTAPLTIC 773
           SP   + G NT PLTIC
Sbjct: 446 SPCLPNEGTNTDPLTIC 462


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  189 bits (480), Expect = 8e-48
 Identities = 134/475 (28%), Positives = 220/475 (46%), Gaps = 44/475 (9%)

Query: 308 DTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASG---SRSPGCPRCQDSHERKSP 364
           D    P C     +PV   C  + C     ++ + +  G     SP CP C++      P
Sbjct: 12  DEVNCPICQGTLREPVTIDCGHNFCR--ACLTRYCEIPGPDLEESPTCPLCKEPFR---P 66

Query: 365 GSLSPQ-PLPQCKRHLKQVQLL--------------------FCEDHDEPICLICSLSQE 403
           GS  P   L     +++++QL+                    FCED +  +C++C  + E
Sbjct: 67  GSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGE 126

Query: 404 HQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQ 463
           H  H +R +E+ A  ++++I K L+ L+K R+  +E +S   ++    L Q    +Q+V 
Sbjct: 127 HATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVI 186

Query: 464 RKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQS 523
            +   +  FLE+Q+   +A LE     + + R  +D  V+ +I    ALI ELE K  + 
Sbjct: 187 SEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERP 246

Query: 524 EWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEME 583
             ELL DI   L R +T    +      E+ Q+I+   Q++  +++  K F E L  E++
Sbjct: 247 ARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELD 306

Query: 584 MFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVL 643
                          ++ LD +T++P L+ S+D +  +   KW+  PD PQRFD    VL
Sbjct: 307 Y-----------EPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVL 355

Query: 644 GSPSFLSGRRYW--EVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQA 701
                  GR  W   +++    +  +G     + RKG + L PE G W V  +      A
Sbjct: 356 AHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAV-RLAWGFVSA 414

Query: 702 SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIF 756
               PTRL +KE P++V + +DY VG ++F N   R  IYTF + SF+  + P F
Sbjct: 415 LGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTF-TASFTRKVIPFF 468


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score =  174 bits (442), Expect = 2e-43
 Identities = 92/189 (48%), Positives = 124/189 (65%), Gaps = 6/189 (3%)

Query: 593 AQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGR 652
           A  HAV+V LD +TA+P+L   +D KSVRL +  ++LP+  +RFDS   VLG  +F SGR
Sbjct: 298 ATLHAVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGR 357

Query: 653 RYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIK 712
            YWEVEVGD+T W +G C+ ++ +KG   ++PENG+W V  +  N Y A +   T L + 
Sbjct: 358 HYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAV-ELYGNGYWALTPLRTPLPLA 416

Query: 713 EPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTI 772
            PP+RVGIF+DY  G ISFYN+   S IYTF++ +FSGPL+P F       GK   PLTI
Sbjct: 417 GPPRRVGIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFC--LWSSGKK--PLTI 472

Query: 773 CPVGGQGPD 781
           CP+   GP+
Sbjct: 473 CPI-ADGPE 480


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  174 bits (441), Expect = 3e-43
 Identities = 135/482 (28%), Positives = 230/482 (47%), Gaps = 49/482 (10%)

Query: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPR-CQDSHERKSP------G 365
           P C+    DP+  +C  + C          QA  +  P C   CQ ++   +P       
Sbjct: 42  PLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLDKLVE 101

Query: 366 SLSPQPL----PQCKRHLKQVQLLFCEDHDEPICLIC-----SLSQEHQGHRVRPI---- 412
            +   PL    PQC  H + ++L F +   + IC  C     S+ Q  +  ++       
Sbjct: 102 KIKKLPLLKGHPQCPEHGENLKL-FSKPDGKLICFQCKDARLSVGQSKEFLQISDAVHFF 160

Query: 413 -EEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYY 471
            EE+A++ + +++  L+ L+ LR   +E  +  +E  +        L+Q V  +  +++ 
Sbjct: 161 TEELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENKLH-------LQQHVSMEFLKLHQ 212

Query: 472 FLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAK-ECQSEWELLQD 530
           FL  +E   +  L + G+ + +  +   +++ +   L   ++  ++AK E Q+ ++ L+D
Sbjct: 213 FLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKD 272

Query: 531 IGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPEL 590
           I  +LH  +     +   T + I +K+ L   K        +   +TL   +        
Sbjct: 273 ITTLLHSLEQGM--KVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLT---- 326

Query: 591 IGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLS 650
                      LD +TA+PNL+ S    SV  G+  + +PD P+RFDS + VLGS  F S
Sbjct: 327 -----------LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTS 375

Query: 651 GRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLL 710
           G+ YWEVEV  KT W +G  + SI RKG+  L+PE G+W++ +  + + +A  +P   L 
Sbjct: 376 GKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLT 435

Query: 711 IKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPL 770
           +     +VGI++DY  G +SFYN    +HIYTF++ +F   L P F P   DGG+N  PL
Sbjct: 436 LTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPL 494

Query: 771 TI 772
            I
Sbjct: 495 HI 496


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  171 bits (434), Expect = 2e-42
 Identities = 155/505 (30%), Positives = 232/505 (45%), Gaps = 78/505 (15%)

Query: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQAS--GSRSPGCPRCQDSH----------- 359
           P C     +P+   C    C     VS     +  G +S  CP C  S+           
Sbjct: 16  PICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKS-SCPVCGISYSFEHLQANQHL 74

Query: 360 ----ERKSPGSLSP---QPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPI 412
               ER     LSP   +    C  H +++ LLFC++  + IC +C  SQEH+GH     
Sbjct: 75  ANIVERLKEVKLSPDNGKKRDLCDHHGEKL-LLFCKEDRKVICWLCERSQEHRGHHTVLT 133

Query: 413 EEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYF 472
           EEV  E ++K+Q  L+ LKK  +  E+  +   E+  S+  Q +  +QR+Q + +Q+   
Sbjct: 134 EEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSI 193

Query: 473 LEQQEHFFVASL-EDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531
           L  +E   +  L E+  + + +  +A D  V Q   L+  LI ++E +   S  ELLQD+
Sbjct: 194 LNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQK-QLVRELISDVECRSQWSTMELLQDM 252

Query: 532 GDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTK--YFSETLRSEMEMFNVPE 589
             I+          KW+    +K        K + V K  K  + +  L   ++MF   E
Sbjct: 253 SGIM----------KWSEIWRLK--------KPKMVSKKLKTVFHAPDLSRMLQMFR--E 292

Query: 590 LIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFL 649
           L   + + V+V L++     NL+ S+D + V     W   P     +     VLGS  F 
Sbjct: 293 LTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIW---PFQCYNYG----VLGSQYFS 345

Query: 650 SGRRYWEVEVGDKTAWILGA-CKT-------SISRKGN-----MTLSPENGYWVVIMMKE 696
           SG+ YWEV+V  KTAWILG  C+T        + R  N         P  GYWV+ +  +
Sbjct: 346 SGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNK 405

Query: 697 NEY-----QASSVPPT-RLLIKEPPKRVGIFVDYRVGSISFYNVTAR-SHIYTFASCSFS 749
            +Y       SS P    L +  PP RVG+F+DY  G +SF+NVT+  S IY F+ C FS
Sbjct: 406 CKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFS 465

Query: 750 GPLQPIFSPGTRDGGKNTAPLTICP 774
            P+ P F+P         AP+T+CP
Sbjct: 466 QPVYPYFNP-----WNCPAPMTLCP 485


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  171 bits (434), Expect = 2e-42
 Identities = 155/505 (30%), Positives = 232/505 (45%), Gaps = 78/505 (15%)

Query: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQAS--GSRSPGCPRCQDSH----------- 359
           P C     +P+   C    C     VS     +  G +S  CP C  S+           
Sbjct: 16  PICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKS-SCPVCGISYSFEHLQANQHL 74

Query: 360 ----ERKSPGSLSP---QPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPI 412
               ER     LSP   +    C  H +++ LLFC++  + IC +C  SQEH+GH     
Sbjct: 75  ANIVERLKEVKLSPDNGKKRDLCDHHGEKL-LLFCKEDRKVICWLCERSQEHRGHHTVLT 133

Query: 413 EEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYF 472
           EEV  E ++K+Q  L+ LKK  +  E+  +   E+  S+  Q +  +QR+Q + +Q+   
Sbjct: 134 EEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSI 193

Query: 473 LEQQEHFFVASL-EDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531
           L  +E   +  L E+  + + +  +A D  V Q   L+  LI ++E +   S  ELLQD+
Sbjct: 194 LNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQK-QLVRELISDVECRSQWSTMELLQDM 252

Query: 532 GDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTK--YFSETLRSEMEMFNVPE 589
             I+          KW+    +K        K + V K  K  + +  L   ++MF   E
Sbjct: 253 SGIM----------KWSEIWRLK--------KPKMVSKKLKTVFHAPDLSRMLQMFR--E 292

Query: 590 LIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFL 649
           L   + + V+V L++     NL+ S+D + V     W   P     +     VLGS  F 
Sbjct: 293 LTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIW---PFQCYNYG----VLGSQYFS 345

Query: 650 SGRRYWEVEVGDKTAWILGA-CKT-------SISRKGN-----MTLSPENGYWVVIMMKE 696
           SG+ YWEV+V  KTAWILG  C+T        + R  N         P  GYWV+ +  +
Sbjct: 346 SGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNK 405

Query: 697 NEY-----QASSVPPT-RLLIKEPPKRVGIFVDYRVGSISFYNVTAR-SHIYTFASCSFS 749
            +Y       SS P    L +  PP RVG+F+DY  G +SF+NVT+  S IY F+ C FS
Sbjct: 406 CKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFS 465

Query: 750 GPLQPIFSPGTRDGGKNTAPLTICP 774
            P+ P F+P         AP+T+CP
Sbjct: 466 QPVYPYFNP-----WNCPAPMTLCP 485


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  171 bits (434), Expect = 2e-42
 Identities = 155/505 (30%), Positives = 232/505 (45%), Gaps = 78/505 (15%)

Query: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQAS--GSRSPGCPRCQDSH----------- 359
           P C     +P+   C    C     VS     +  G +S  CP C  S+           
Sbjct: 370 PICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKS-SCPVCGISYSFEHLQANQHL 428

Query: 360 ----ERKSPGSLSP---QPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPI 412
               ER     LSP   +    C  H +++ LLFC++  + IC +C  SQEH+GH     
Sbjct: 429 ANIVERLKEVKLSPDNGKKRDLCDHHGEKL-LLFCKEDRKVICWLCERSQEHRGHHTVLT 487

Query: 413 EEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYF 472
           EEV  E ++K+Q  L+ LKK  +  E+  +   E+  S+  Q +  +QR+Q + +Q+   
Sbjct: 488 EEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSI 547

Query: 473 LEQQEHFFVASL-EDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531
           L  +E   +  L E+  + + +  +A D  V Q   L+  LI ++E +   S  ELLQD+
Sbjct: 548 LNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQK-QLVRELISDVECRSQWSTMELLQDM 606

Query: 532 GDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTK--YFSETLRSEMEMFNVPE 589
             I+          KW+    +K        K + V K  K  + +  L   ++MF   E
Sbjct: 607 SGIM----------KWSEIWRLK--------KPKMVSKKLKTVFHAPDLSRMLQMFR--E 646

Query: 590 LIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFL 649
           L   + + V+V L++     NL+ S+D + V     W   P     +     VLGS  F 
Sbjct: 647 LTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIW---PFQCYNYG----VLGSQYFS 699

Query: 650 SGRRYWEVEVGDKTAWILGA-CKT-------SISRKGN-----MTLSPENGYWVVIMMKE 696
           SG+ YWEV+V  KTAWILG  C+T        + R  N         P  GYWV+ +  +
Sbjct: 700 SGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNK 759

Query: 697 NEY-----QASSVPPT-RLLIKEPPKRVGIFVDYRVGSISFYNVTAR-SHIYTFASCSFS 749
            +Y       SS P    L +  PP RVG+F+DY  G +SF+NVT+  S IY F+ C FS
Sbjct: 760 CKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFS 819

Query: 750 GPLQPIFSPGTRDGGKNTAPLTICP 774
            P+ P F+P         AP+T+CP
Sbjct: 820 QPVYPYFNP-----WNCPAPMTLCP 839



 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 74/260 (28%), Positives = 118/260 (45%), Gaps = 26/260 (10%)

Query: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSP-GCPRCQDSHERKSPGSLSP-Q 370
           P C     +P+   C    C      +G     G      CP CQ S++   PG+L P +
Sbjct: 44  PICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ---PGNLRPNR 100

Query: 371 PLPQCKRHLKQVQL-------------------LFCEDHDEPICLICSLSQEHQGHRVRP 411
            L    R L++V L                   LFC++  + IC +C  SQEH+GH    
Sbjct: 101 HLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHTFL 160

Query: 412 IEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYY 471
           +EEVA E+++K Q+ L+ LK   +  E+  ++  EK  S+  Q E  + R+Q +  Q+  
Sbjct: 161 VEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRN 220

Query: 472 FLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDI 531
            L++ E   +  LE   +   +I +  +  +      L  LI +LE +   S  ELLQD+
Sbjct: 221 ILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDV 280

Query: 532 GDILHRAK--TVPVPEKWTT 549
            D+  R++  T+  PE   T
Sbjct: 281 SDVTERSEFWTLRKPEALPT 300


>gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo
           sapiens]
          Length = 407

 Score =  169 bits (428), Expect = 9e-42
 Identities = 89/208 (42%), Positives = 126/208 (60%), Gaps = 12/208 (5%)

Query: 567 VEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKW 626
           VE+  K  ++ L+ E+             HA +V+LD +TA+P L  S+D +SVR G   
Sbjct: 186 VEQEEKEIAQQLQEELRWRRT------FLHAADVVLDPDTAHPELFLSEDRRSVRRGPYR 239

Query: 627 ERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPEN 686
           +R+PD P+RFDS   VLG  SF SG+ YWEVEV +   W +G C+ S+ RKG + L P+N
Sbjct: 240 QRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVMVWTVGVCRHSVERKGEVLLIPQN 299

Query: 687 GYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASC 746
           G+W + M   N+Y+A S P   L +KE   RVG+F+DY  G +SFYN+  RSHIYT    
Sbjct: 300 GFWTLEMF-GNQYRALSSPERILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRS 358

Query: 747 SFSGPLQPIFSPGTRDGGKNTAPLTICP 774
           +F+ P++P F  G+ D     +P+ ICP
Sbjct: 359 AFTVPVRPFFRLGSDD-----SPIFICP 381


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score =  169 bits (428), Expect = 9e-42
 Identities = 89/208 (42%), Positives = 126/208 (60%), Gaps = 12/208 (5%)

Query: 567 VEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKW 626
           VE+  K  ++ L+ E+             HA +V+LD +TA+P L  S+D +SVR G   
Sbjct: 302 VEQEEKEIAQQLQEELRWRRT------FLHAADVVLDPDTAHPELFLSEDRRSVRRGPYR 355

Query: 627 ERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPEN 686
           +R+PD P+RFDS   VLG  SF SG+ YWEVEV +   W +G C+ S+ RKG + L P+N
Sbjct: 356 QRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVMVWTVGVCRHSVERKGEVLLIPQN 415

Query: 687 GYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASC 746
           G+W + M   N+Y+A S P   L +KE   RVG+F+DY  G +SFYN+  RSHIYT    
Sbjct: 416 GFWTLEMF-GNQYRALSSPERILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRS 474

Query: 747 SFSGPLQPIFSPGTRDGGKNTAPLTICP 774
           +F+ P++P F  G+ D     +P+ ICP
Sbjct: 475 AFTVPVRPFFRLGSDD-----SPIFICP 497


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  168 bits (426), Expect = 2e-41
 Identities = 131/440 (29%), Positives = 213/440 (48%), Gaps = 68/440 (15%)

Query: 367 LSP--QPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQ 424
           LSP  Q +  C RH +++ LLFC++  + IC +C  SQEH+GH   P EEVA E++ K+Q
Sbjct: 85  LSPEGQKVDHCARHGEKL-LLFCQEDGKVICWLCERSQEHRGHHTFPTEEVAQEYQVKLQ 143

Query: 425 KQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASL 484
             LE L++ ++  EE  +   E+  S+  Q +  K  V    EQ+   L+ +E   + +L
Sbjct: 144 AALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLRDILDWEESNELQNL 203

Query: 485 EDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVP 544
           E   + + +     +T + Q    L  LI +LE +   S  ELLQ +  ++ R + V + 
Sbjct: 204 EKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQGVDGVIKRTENVTLK 263

Query: 545 EKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDA 604
           +  T P+  ++  +                +  L+  +E+F   EL   + + V+V    
Sbjct: 264 KPETFPKNQRRVFR----------------APDLKGMLEVFR--ELTDVRRYWVDV---- 301

Query: 605 ETAYPN----LIFSDDLKSV----------RLGNKWERLPDGPQRFDSCIIVLGSPSFLS 650
            T  PN     + S+D + V            G +++   +    F+ C  +LGS S  S
Sbjct: 302 -TVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVN----FNYCTGILGSQSITS 356

Query: 651 GRRYWEVEVGDKTAWILGAC-----KTSISRKGNMTLSPENGYWVVIM--------MKEN 697
           G+ YWEV+V  KTAWILG C         + + N    P+ GYWV+ +         +++
Sbjct: 357 GKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDS 416

Query: 698 EYQASSVP---PTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSH-IYTFASCSFSGPLQ 753
            +   SVP   P  ++I   P RVG+F+DY   ++SF+N+T     IY F+ CSFS P+ 
Sbjct: 417 SFHTPSVPFIVPLSVII--CPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVF 474

Query: 754 PIFSPGTRDGGKNTAPLTIC 773
           P  +P      K   P+T+C
Sbjct: 475 PYLNP-----RKCGVPMTLC 489


>gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]
          Length = 341

 Score =  168 bits (426), Expect = 2e-41
 Identities = 109/361 (30%), Positives = 186/361 (51%), Gaps = 27/361 (7%)

Query: 413 EEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYF 472
           EE+A++ + +++  L+ L+ LR   +E  +  +E  +        L+Q V  +  +++ F
Sbjct: 3   EELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENKLH-------LQQHVSMEFLKLHQF 54

Query: 473 LEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAK-ECQSEWELLQDI 531
           L  +E   +  L + G+ + +  +   +++ +   L   ++  ++AK E Q+ ++ L+DI
Sbjct: 55  LHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDI 114

Query: 532 GDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELI 591
             +LH  +     +   T + I +K+ L   K        +   +TL   +         
Sbjct: 115 TTLLHSLEQGM--KVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLT----- 167

Query: 592 GAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSG 651
                     LD +TA+PNL+ S    SV  G+  + +PD P+RFDS + VLGS  F SG
Sbjct: 168 ----------LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSG 217

Query: 652 RRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLI 711
           + YWEVEV  KT W +G  + SI RKG+  L+PE G+W++ +  + + +A  +P   L +
Sbjct: 218 KWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTL 277

Query: 712 KEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLT 771
                +VGI++DY  G +SFYN    +HIYTF++ +F   L P F P   DGG+N  PL 
Sbjct: 278 TNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPLH 336

Query: 772 I 772
           I
Sbjct: 337 I 337


>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
           sapiens]
          Length = 584

 Score =  167 bits (424), Expect = 3e-41
 Identities = 85/178 (47%), Positives = 114/178 (64%), Gaps = 5/178 (2%)

Query: 599 NVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVE 658
           +VILD +TA   L+ S+D +SV+   +   LPD P+RF+    VLG  +F SGR YWEVE
Sbjct: 341 DVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYWEVE 400

Query: 659 VGDKTAWILGACKTSISRK-GNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKR 717
           VGD+  W +G C  ++ RK G + ++PENGYW + +   N+Y+A + P T L + EPP++
Sbjct: 401 VGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRK 460

Query: 718 VGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPV 775
           VGIF+DY  G ISFYN T  SHIYTF   SFS PL P+F   T +       LTICP+
Sbjct: 461 VGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLE----PTALTICPI 514


>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
           sapiens]
          Length = 542

 Score =  167 bits (424), Expect = 3e-41
 Identities = 85/178 (47%), Positives = 114/178 (64%), Gaps = 5/178 (2%)

Query: 599 NVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVE 658
           +VILD +TA   L+ S+D +SV+   +   LPD P+RF+    VLG  +F SGR YWEVE
Sbjct: 299 DVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYWEVE 358

Query: 659 VGDKTAWILGACKTSISRK-GNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKR 717
           VGD+  W +G C  ++ RK G + ++PENGYW + +   N+Y+A + P T L + EPP++
Sbjct: 359 VGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRK 418

Query: 718 VGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPV 775
           VGIF+DY  G ISFYN T  SHIYTF   SFS PL P+F   T +       LTICP+
Sbjct: 419 VGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLE----PTALTICPI 472


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,685,942
Number of Sequences: 37866
Number of extensions: 1986262
Number of successful extensions: 8197
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 465
Number of HSP's that attempted gapping in prelim test: 7035
Number of HSP's gapped (non-prelim): 1371
length of query: 781
length of database: 18,247,518
effective HSP length: 110
effective length of query: 671
effective length of database: 14,082,258
effective search space: 9449195118
effective search space used: 9449195118
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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