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Search of human proteins with 4557415
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557415 cystathionine-beta-synthase [Homo sapiens]
(551 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557415 cystathionine-beta-synthase [Homo sapiens] 1112 0.0
gi|11345492 serine racemase [Homo sapiens] 68 2e-11
gi|19923959 serine dehydratase-like [Homo sapiens] 39 0.009
gi|8567388 period 3 [Homo sapiens] 35 0.18
gi|110349721 titin isoform novex-3 [Homo sapiens] 33 0.89
gi|199562283 retrotransposon-like 1 [Homo sapiens] 33 0.89
gi|110349719 titin isoform N2-A [Homo sapiens] 33 0.89
gi|110349717 titin isoform novex-2 [Homo sapiens] 33 0.89
gi|110349713 titin isoform novex-1 [Homo sapiens] 33 0.89
gi|110349715 titin isoform N2-B [Homo sapiens] 33 0.89
gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens] 33 0.89
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 32 1.2
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 32 1.2
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 32 1.2
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 32 1.2
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 32 1.2
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 32 1.2
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 32 1.2
gi|118498339 EMI domain containing 2 [Homo sapiens] 31 2.6
gi|50345997 E1A binding protein p300 [Homo sapiens] 31 3.4
gi|239756704 PREDICTED: similar to NLRP1 protein [Homo sapiens] 31 3.4
gi|239751199 PREDICTED: hypothetical protein XP_002347754 [Homo ... 31 3.4
gi|239746599 PREDICTED: hypothetical protein XP_002343795 [Homo ... 31 3.4
gi|239745689 PREDICTED: hypothetical protein XP_002343527 [Homo ... 31 3.4
gi|4505253 mutS homolog 5 isoform c [Homo sapiens] 31 3.4
gi|26638664 mutS homolog 5 isoform b [Homo sapiens] 31 3.4
gi|26638662 mutS homolog 5 isoform a [Homo sapiens] 31 3.4
gi|26638666 mutS homolog 5 isoform c [Homo sapiens] 31 3.4
gi|27734897 hypothetical protein LOC203111 [Homo sapiens] 31 3.4
gi|189571667 zinc finger protein 696 [Homo sapiens] 30 4.4
>gi|4557415 cystathionine-beta-synthase [Homo sapiens]
Length = 551
Score = 1112 bits (2876), Expect = 0.0
Identities = 551/551 (100%), Positives = 551/551 (100%)
Query: 1 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 60
MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA
Sbjct: 1 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 60
Query: 61 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 120
SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD
Sbjct: 61 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 120
Query: 121 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV
Sbjct: 121 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 181 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 240
LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI
Sbjct: 181 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 240
Query: 241 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 300
LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT
Sbjct: 241 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 300
Query: 301 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 360
YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA
Sbjct: 301 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 360
Query: 361 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 420
AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS
Sbjct: 361 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 420
Query: 421 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 480
APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG
Sbjct: 421 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 480
Query: 481 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 540
KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL
Sbjct: 481 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 540
Query: 541 NFVAAQERDQK 551
NFVAAQERDQK
Sbjct: 541 NFVAAQERDQK 551
>gi|11345492 serine racemase [Homo sapiens]
Length = 340
Score = 67.8 bits (164), Expect = 2e-11
Identities = 75/270 (27%), Positives = 110/270 (40%), Gaps = 21/270 (7%)
Query: 105 LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYR 164
L KCE F GS K R +L + D + ++ +SGN G L AA + G
Sbjct: 42 LFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIP 101
Query: 165 CIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYR 224
IV+P+ K ++A GA IV S ES VA R+ E I+
Sbjct: 102 AYIVVPQTAPDCKKLAIQAYGASIVYCE-----PSDESRENVAKRVTEE--TEGIMVHPN 154
Query: 225 NASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEG 284
+A T A E+L Q +D LV VG GG + GIA +K P ++ +P
Sbjct: 155 QEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSN 213
Query: 285 SILAEPEEL-NQTEQTTYEVE--------GIGYDFIPTVLDRTVVDKWFKSNDEEAFTFA 335
+ +L + Y E IG + P + R +VD F ++E
Sbjct: 214 ADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPII--RDLVDDIFTVTEDEIKCAT 271
Query: 336 RMLIAQEGLLCGGSAGSTVAVAVKAAQELQ 365
+++ + LL +AG V VA +Q Q
Sbjct: 272 QLVWERMKLLIEPTAG--VGVAAVLSQHFQ 299
>gi|19923959 serine dehydratase-like [Homo sapiens]
Length = 329
Score = 39.3 bits (90), Expect = 0.009
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 19/187 (10%)
Query: 87 TPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPT 146
TP++ + + G+ L KCE GS K R ++ + G ++ +
Sbjct: 18 TPLLESWALSQVAGMPVFL--KCENVQPSGSFKIRGIGHFCQEMAKKGCRH----LVCSS 71
Query: 147 SGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTP---TNARFDSPESH 203
GN GI A AA G IV+PE S + V L+ GAE+ T A + E
Sbjct: 72 GGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELA 131
Query: 204 VGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITG 263
W +N P H L +AS E+ LV +VG GG + G
Sbjct: 132 KRDGW--ENVPPFDHPLIWKGHAS--------LVQELKAVLRTPPGALVLAVGGGGLLAG 181
Query: 264 IARKLKE 270
+ L E
Sbjct: 182 VVAGLLE 188
>gi|8567388 period 3 [Homo sapiens]
Length = 1201
Score = 35.0 bits (79), Expect = 0.18
Identities = 27/84 (32%), Positives = 32/84 (38%), Gaps = 13/84 (15%)
Query: 3 SETPQAEVGP--TGCPHRSGP-HSAKGSLEKGSPEDKEAKEPL----------WIRPDAP 49
SE+ A G TG P R P H +L GSP K P P P
Sbjct: 962 SESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTGSPPMKNPSHP 1021
Query: 50 SRCTWQLGRPASESPHHHTAPAKS 73
+ T +G P S +P H TA S
Sbjct: 1022 TASTLSMGLPPSRTPSHPTATVLS 1045
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 32.7 bits (73), Expect = 0.89
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 40/241 (16%)
Query: 87 TPMVRINKI-GKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGD---TI 142
TP+ +N I G K L+C++ SV D S++ + E+ +KP D I
Sbjct: 2449 TPLKDVNVIEGTKAVLECKV-----------SVPDVTSVKWYLNDEQ---IKPDDRVQAI 2494
Query: 143 IEPTSGNTGIGLALAAAVRGYRCIIVMPE---KMSSEKVDVLRALGAEIVRTPTNARFDS 199
++ T I A+ Y+ I+ E +S EK+ ++R L N F+
Sbjct: 2495 VKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV 2554
Query: 200 PESHVG--VAWRLKN-EIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVG 256
SH G V W K+ EI S +Y+ ++ Y T +++ +GK
Sbjct: 2555 ELSHSGIDVLWNFKDKEIKPS---SKYKIEAHGKI-YKLTVLNMMKDDEGKYTFYAGENM 2610
Query: 257 TGGTIT----GIARKLKEKCPG--------CRIIGVDPEGSILAEPEELNQTEQTTYEVE 304
T G +T I++ L ++ C + D +G L + + L T E +
Sbjct: 2611 TSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESD 2670
Query: 305 G 305
G
Sbjct: 2671 G 2671
>gi|199562283 retrotransposon-like 1 [Homo sapiens]
Length = 1358
Score = 32.7 bits (73), Expect = 0.89
Identities = 40/195 (20%), Positives = 82/195 (42%), Gaps = 45/195 (23%)
Query: 213 EIPNSHILDQYRNASNPLAHYDTTADEILQQ----CDGKLDMLVASVGTGGTITGIARKL 268
E+P + D +S P + +++LQ C+G + G ++G + ++
Sbjct: 68 ELPTDLLQDMEEPSSGPRKEIEDPPNDLLQDLEESCNG------SHQARGDPLSGASDRM 121
Query: 269 KEKCPGCRIIGVDPEGSILAE--------------PEELNQTEQTTYEVEGIGYDFIPTV 314
KE V+P G+ + P+E NQTE +T E+
Sbjct: 122 KEA-------SVNPSGAREEQEAHTDLKESGREETPQEQNQTEHSTAEL---------MA 165
Query: 315 LDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVIL 374
+ R+++ +F+ D + + +A+E L+ G +AG A + + +E +V+
Sbjct: 166 MVRSIISLYFRMQDLK----EQQRVAEEILIKGINAGQLPA-PKHFSGDRREFHEFIVLC 220
Query: 375 PDSVRNYMTKFLSDR 389
++++Y F +DR
Sbjct: 221 QLTLQSYPRMFYNDR 235
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 32.7 bits (73), Expect = 0.89
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 40/241 (16%)
Query: 87 TPMVRINKI-GKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGD---TI 142
TP+ +N I G K L+C++ SV D S++ + E+ +KP D I
Sbjct: 2449 TPLKDVNVIEGTKAVLECKV-----------SVPDVTSVKWYLNDEQ---IKPDDRVQAI 2494
Query: 143 IEPTSGNTGIGLALAAAVRGYRCIIVMPE---KMSSEKVDVLRALGAEIVRTPTNARFDS 199
++ T I A+ Y+ I+ E +S EK+ ++R L N F+
Sbjct: 2495 VKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV 2554
Query: 200 PESHVG--VAWRLKN-EIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVG 256
SH G V W K+ EI S +Y+ ++ Y T +++ +GK
Sbjct: 2555 ELSHSGIDVLWNFKDKEIKPS---SKYKIEAHGKI-YKLTVLNMMKDDEGKYTFYAGENM 2610
Query: 257 TGGTIT----GIARKLKEKCPG--------CRIIGVDPEGSILAEPEELNQTEQTTYEVE 304
T G +T I++ L ++ C + D +G L + + L T E +
Sbjct: 2611 TSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESD 2670
Query: 305 G 305
G
Sbjct: 2671 G 2671
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 32.7 bits (73), Expect = 0.89
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 40/241 (16%)
Query: 87 TPMVRINKI-GKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGD---TI 142
TP+ +N I G K L+C++ SV D S++ + E+ +KP D I
Sbjct: 2403 TPLKDVNVIEGTKAVLECKV-----------SVPDVTSVKWYLNDEQ---IKPDDRVQAI 2448
Query: 143 IEPTSGNTGIGLALAAAVRGYRCIIVMPE---KMSSEKVDVLRALGAEIVRTPTNARFDS 199
++ T I A+ Y+ I+ E +S EK+ ++R L N F+
Sbjct: 2449 VKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV 2508
Query: 200 PESHVG--VAWRLKN-EIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVG 256
SH G V W K+ EI S +Y+ ++ Y T +++ +GK
Sbjct: 2509 ELSHSGIDVLWNFKDKEIKPS---SKYKIEAHGKI-YKLTVLNMMKDDEGKYTFYAGENM 2564
Query: 257 TGGTIT----GIARKLKEKCPG--------CRIIGVDPEGSILAEPEELNQTEQTTYEVE 304
T G +T I++ L ++ C + D +G L + + L T E +
Sbjct: 2565 TSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESD 2624
Query: 305 G 305
G
Sbjct: 2625 G 2625
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 32.7 bits (73), Expect = 0.89
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 40/241 (16%)
Query: 87 TPMVRINKI-GKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGD---TI 142
TP+ +N I G K L+C++ SV D S++ + E+ +KP D I
Sbjct: 2403 TPLKDVNVIEGTKAVLECKV-----------SVPDVTSVKWYLNDEQ---IKPDDRVQAI 2448
Query: 143 IEPTSGNTGIGLALAAAVRGYRCIIVMPE---KMSSEKVDVLRALGAEIVRTPTNARFDS 199
++ T I A+ Y+ I+ E +S EK+ ++R L N F+
Sbjct: 2449 VKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV 2508
Query: 200 PESHVG--VAWRLKN-EIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVG 256
SH G V W K+ EI S +Y+ ++ Y T +++ +GK
Sbjct: 2509 ELSHSGIDVLWNFKDKEIKPS---SKYKIEAHGKI-YKLTVLNMMKDDEGKYTFYAGENM 2564
Query: 257 TGGTIT----GIARKLKEKCPG--------CRIIGVDPEGSILAEPEELNQTEQTTYEVE 304
T G +T I++ L ++ C + D +G L + + L T E +
Sbjct: 2565 TSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESD 2624
Query: 305 G 305
G
Sbjct: 2625 G 2625
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 32.7 bits (73), Expect = 0.89
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 40/241 (16%)
Query: 87 TPMVRINKI-GKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGD---TI 142
TP+ +N I G K L+C++ SV D S++ + E+ +KP D I
Sbjct: 2403 TPLKDVNVIEGTKAVLECKV-----------SVPDVTSVKWYLNDEQ---IKPDDRVQAI 2448
Query: 143 IEPTSGNTGIGLALAAAVRGYRCIIVMPE---KMSSEKVDVLRALGAEIVRTPTNARFDS 199
++ T I A+ Y+ I+ E +S EK+ ++R L N F+
Sbjct: 2449 VKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV 2508
Query: 200 PESHVG--VAWRLKN-EIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVG 256
SH G V W K+ EI S +Y+ ++ Y T +++ +GK
Sbjct: 2509 ELSHSGIDVLWNFKDKEIKPS---SKYKIEAHGKI-YKLTVLNMMKDDEGKYTFYAGENM 2564
Query: 257 TGGTIT----GIARKLKEKCPG--------CRIIGVDPEGSILAEPEELNQTEQTTYEVE 304
T G +T I++ L ++ C + D +G L + + L T E +
Sbjct: 2565 TSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESD 2624
Query: 305 G 305
G
Sbjct: 2625 G 2625
>gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens]
Length = 869
Score = 32.7 bits (73), Expect = 0.89
Identities = 15/54 (27%), Positives = 25/54 (46%)
Query: 421 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQ 474
+P TV P + R G PVV+ G I+G++T N+ L +++
Sbjct: 810 SPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTYEFLQARLR 863
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/66 (28%), Positives = 28/66 (42%)
Query: 13 TGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAK 72
T ++GP GS E+ S ++EA+ ++P + PA ESP AP
Sbjct: 779 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 838
Query: 73 SPKILP 78
K P
Sbjct: 839 PGKTGP 844
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 9/83 (10%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPE--------DKEAKEPLWIRPDAPSRCTWQ 55
E+P+ P P ++GP AK K + D E + P +P +
Sbjct: 303 ESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 361
Query: 56 LGRPASESPHHHTAPAKSPKILP 78
PA ESP APA K P
Sbjct: 362 ASAPAKESPRKGAAPAPPRKTGP 384
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/66 (28%), Positives = 28/66 (42%)
Query: 13 TGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAK 72
T ++GP GS E+ S ++EA+ ++P + PA ESP AP
Sbjct: 856 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Query: 73 SPKILP 78
K P
Sbjct: 916 PGKTGP 921
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 9/83 (10%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPE--------DKEAKEPLWIRPDAPSRCTWQ 55
E+P+ P P ++GP AK K + D E + P +P +
Sbjct: 380 ESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 56 LGRPASESPHHHTAPAKSPKILP 78
PA ESP APA K P
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP 461
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/66 (28%), Positives = 28/66 (42%)
Query: 13 TGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAK 72
T ++GP GS E+ S ++EA+ ++P + PA ESP AP
Sbjct: 856 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Query: 73 SPKILP 78
K P
Sbjct: 916 PGKTGP 921
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 9/83 (10%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPE--------DKEAKEPLWIRPDAPSRCTWQ 55
E+P+ P P ++GP AK K + D E + P +P +
Sbjct: 380 ESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 56 LGRPASESPHHHTAPAKSPKILP 78
PA ESP APA K P
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP 461
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/66 (28%), Positives = 28/66 (42%)
Query: 13 TGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAK 72
T ++GP GS E+ S ++EA+ ++P + PA ESP AP
Sbjct: 779 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 838
Query: 73 SPKILP 78
K P
Sbjct: 839 PGKTGP 844
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 9/83 (10%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPE--------DKEAKEPLWIRPDAPSRCTWQ 55
E+P+ P P ++GP AK K + D E + P +P +
Sbjct: 303 ESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 361
Query: 56 LGRPASESPHHHTAPAKSPKILP 78
PA ESP APA K P
Sbjct: 362 ASAPAKESPRKGAAPAPPRKTGP 384
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/66 (28%), Positives = 28/66 (42%)
Query: 13 TGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAK 72
T ++GP GS E+ S ++EA+ ++P + PA ESP AP
Sbjct: 856 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Query: 73 SPKILP 78
K P
Sbjct: 916 PGKTGP 921
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 9/83 (10%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPE--------DKEAKEPLWIRPDAPSRCTWQ 55
E+P+ P P ++GP AK K + D E + P +P +
Sbjct: 380 ESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 56 LGRPASESPHHHTAPAKSPKILP 78
PA ESP APA K P
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP 461
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 32.3 bits (72), Expect = 1.2
Identities = 19/66 (28%), Positives = 28/66 (42%)
Query: 13 TGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAK 72
T ++GP GS E+ S ++EA+ ++P + PA ESP AP
Sbjct: 856 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Query: 73 SPKILP 78
K P
Sbjct: 916 PGKTGP 921
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 9/83 (10%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPE--------DKEAKEPLWIRPDAPSRCTWQ 55
E+P+ P P ++GP AK K + D E + P +P +
Sbjct: 380 ESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 56 LGRPASESPHHHTAPAKSPKILP 78
PA ESP APA K P
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP 461
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 32.3 bits (72), Expect = 1.2
Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 7/80 (8%)
Query: 1 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 60
+P+ P GP+ P S PH A P + P RP PSR + RP
Sbjct: 762 IPAAAPLKGPGPSSSP--SLPHQAPLGDSPHLPSPHPTRPPS--RP--PSR-PQSVSRPP 814
Query: 61 SESPHHHTAPAKSPKILPDI 80
SE P H P ++P LP I
Sbjct: 815 SEPPLHPCPPPQAPPTLPGI 834
>gi|118498339 EMI domain containing 2 [Homo sapiens]
Length = 439
Score = 31.2 bits (69), Expect = 2.6
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 6 PQAEVGPTGCPHRSGPHSAKGSLEKGSPEDK-EAKEPLWIRPDAPSRCTWQLGRPASESP 64
P G TG P +GP +KG ++G +K A P + P P ++GRP P
Sbjct: 198 PAGPPGQTGPPGPAGPPGSKG--DRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGP 255
Query: 65 HHHTAPAKSPKILPD 79
PA +P P+
Sbjct: 256 ---PGPAGNPGPSPN 267
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 30.8 bits (68), Expect = 3.4
Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 1 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLG--R 58
MP TP A +G P GP G LE G ++P W + P Q G R
Sbjct: 1956 MPPMTPMAPMGMNPPPMTRGP---SGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPR 2012
Query: 59 PASESPHHHTAP 70
PA S H P
Sbjct: 2013 PAMMSVAQHGQP 2024
>gi|239756704 PREDICTED: similar to NLRP1 protein [Homo sapiens]
Length = 146
Score = 30.8 bits (68), Expect = 3.4
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASE 62
E+ + E P P R GP G+L +G PE +A P P S C +L RP +
Sbjct: 32 ESLRDEPDPDPRPSREGPAGRVGALARGGPEPCDAASP----PGGAS-CAPELARPRED 85
>gi|239751199 PREDICTED: hypothetical protein XP_002347754 [Homo
sapiens]
Length = 146
Score = 30.8 bits (68), Expect = 3.4
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASE 62
E+ + E P P R GP G+L +G PE +A P P S C +L RP +
Sbjct: 32 ESLRDEPDPDPRPSREGPAGRVGALARGGPEPCDAASP----PGGAS-CAPELARPRED 85
>gi|239746599 PREDICTED: hypothetical protein XP_002343795 [Homo
sapiens]
Length = 443
Score = 30.8 bits (68), Expect = 3.4
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 17/85 (20%)
Query: 11 GPTGCPHRSGPHSAKGSLEKGSPEDK----EAKEPLW------------IRPDAPSRCTW 54
G C HR PH +K SP + A P W + D P CT
Sbjct: 36 GSAQCHHRPDPHPPAPGKKKSSPVGRFFPASAMAPPWLPGIVSAAQLKPVLSDLPPHCTR 95
Query: 55 QLGRPASESPHH-HTAPAKSPKILP 78
+P ++ PH H +++ LP
Sbjct: 96 AQCQPLTQRPHSLHLQDSRNASSLP 120
>gi|239745689 PREDICTED: hypothetical protein XP_002343527 [Homo
sapiens]
Length = 146
Score = 30.8 bits (68), Expect = 3.4
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 4 ETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASE 62
E+ + E P P R GP G+L +G PE +A P P S C +L RP +
Sbjct: 32 ESLRDEPDPDPRPSREGPAGRVGALARGGPEPCDAASP----PGGAS-CAPELARPRED 85
>gi|4505253 mutS homolog 5 isoform c [Homo sapiens]
Length = 834
Score = 30.8 bits (68), Expect = 3.4
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Query: 255 VGTGGTITGIARK----LKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDF 310
+G +T +ARK L + P C +I + G +L+ P + E + +E+ G+ + F
Sbjct: 411 MGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMF 470
Query: 311 I 311
+
Sbjct: 471 L 471
>gi|26638664 mutS homolog 5 isoform b [Homo sapiens]
Length = 835
Score = 30.8 bits (68), Expect = 3.4
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Query: 255 VGTGGTITGIARK----LKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDF 310
+G +T +ARK L + P C +I + G +L+ P + E + +E+ G+ + F
Sbjct: 411 MGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMF 470
Query: 311 I 311
+
Sbjct: 471 L 471
>gi|26638662 mutS homolog 5 isoform a [Homo sapiens]
Length = 851
Score = 30.8 bits (68), Expect = 3.4
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Query: 255 VGTGGTITGIARK----LKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDF 310
+G +T +ARK L + P C +I + G +L+ P + E + +E+ G+ + F
Sbjct: 428 MGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMF 487
Query: 311 I 311
+
Sbjct: 488 L 488
>gi|26638666 mutS homolog 5 isoform c [Homo sapiens]
Length = 834
Score = 30.8 bits (68), Expect = 3.4
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Query: 255 VGTGGTITGIARK----LKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDF 310
+G +T +ARK L + P C +I + G +L+ P + E + +E+ G+ + F
Sbjct: 411 MGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMF 470
Query: 311 I 311
+
Sbjct: 471 L 471
>gi|27734897 hypothetical protein LOC203111 [Homo sapiens]
Length = 374
Score = 30.8 bits (68), Expect = 3.4
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 8/74 (10%)
Query: 460 TLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLS---HILEMDHFALVVHEQI 516
T N+L+ +AG++QP VGK +Q L +T+ + + ILE F EQ
Sbjct: 190 TTENVLTLQIAGELQPQGTVGK-----DEQAPLLETISKENESPEILEGSQFVETAEEQQ 244
Query: 517 QYHSTGKSSQRQMV 530
+ GK Q Q++
Sbjct: 245 LQATLGKEEQPQLL 258
>gi|189571667 zinc finger protein 696 [Homo sapiens]
Length = 374
Score = 30.4 bits (67), Expect = 4.4
Identities = 20/39 (51%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Query: 3 SETPQAEVG-PTGCPHRSGPHSAKGSLEKGSPEDKEAKE 40
S P AE G P G HR GP A GSL G E++EA+E
Sbjct: 45 STEPAAEAGAPEGEGHRGGPPRALGSL--GLCENQEARE 81
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,088,009
Number of Sequences: 37866
Number of extensions: 1064464
Number of successful extensions: 3347
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3297
Number of HSP's gapped (non-prelim): 98
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.