Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4557040
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557040 oncostatin M receptor [Homo sapiens]
(979 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557040 oncostatin M receptor [Homo sapiens] 2024 0.0
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 411 e-114
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 411 e-114
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 137 4e-32
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 135 1e-31
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 111 4e-24
gi|27437045 colony stimulating factor 3 receptor isoform d precu... 92 2e-18
gi|24496783 colony stimulating factor 3 receptor isoform c precu... 92 2e-18
gi|4503081 colony stimulating factor 3 receptor isoform a precur... 92 2e-18
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 73 1e-12
gi|4759328 class I cytokine receptor [Homo sapiens] 65 4e-10
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 62 2e-09
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 62 2e-09
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 62 2e-09
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 59 3e-08
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 57 6e-08
gi|222352127 sidekick 2 [Homo sapiens] 56 2e-07
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 55 4e-07
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 55 4e-07
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 54 9e-07
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 54 9e-07
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 54 9e-07
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 52 4e-06
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 51 6e-06
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 51 6e-06
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 50 8e-06
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 50 1e-05
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 49 3e-05
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 47 7e-05
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 47 7e-05
>gi|4557040 oncostatin M receptor [Homo sapiens]
Length = 979
Score = 2024 bits (5245), Expect = 0.0
Identities = 979/979 (100%), Positives = 979/979 (100%)
Query: 1 MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYH 60
MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYH
Sbjct: 1 MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYH 60
Query: 61 QELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLHWSWESELPLECATHFVRIKSLVDD 120
QELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLHWSWESELPLECATHFVRIKSLVDD
Sbjct: 61 QELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLHWSWESELPLECATHFVRIKSLVDD 120
Query: 121 AKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCY 180
AKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCY
Sbjct: 121 AKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCY 180
Query: 181 LEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEP 240
LEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEP
Sbjct: 181 LEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEP 240
Query: 241 KDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQ 300
KDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQ
Sbjct: 241 KDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQ 300
Query: 301 DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRN 360
DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRN
Sbjct: 301 DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRN 360
Query: 361 NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG 420
NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG
Sbjct: 361 NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG 420
Query: 421 QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSS 480
QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSS
Sbjct: 421 QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSS 480
Query: 481 SELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTE 540
SELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTE
Sbjct: 481 SELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTE 540
Query: 541 GGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFR 600
GGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFR
Sbjct: 541 GGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFR 600
Query: 601 IYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGY 660
IYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGY
Sbjct: 601 IYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGY 660
Query: 661 HVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSA 720
HVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSA
Sbjct: 661 HVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSA 720
Query: 721 GEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKS 780
GEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKS
Sbjct: 721 GEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKS 780
Query: 781 SILSLIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYL 840
SILSLIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYL
Sbjct: 781 SILSLIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYL 840
Query: 841 LPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALEKN 900
LPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALEKN
Sbjct: 841 LPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALEKN 900
Query: 901 YMNSLGEIPAGETSLNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPP 960
YMNSLGEIPAGETSLNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPP
Sbjct: 901 YMNSLGEIPAGETSLNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPP 960
Query: 961 TENSSLSSITLLDPGEHYC 979
TENSSLSSITLLDPGEHYC
Sbjct: 961 TENSSLSSITLLDPGEHYC 979
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 411 bits (1056), Expect = e-114
Identities = 264/806 (32%), Positives = 421/806 (52%), Gaps = 54/806 (6%)
Query: 30 LPLTPVSLKVSTNSTRQSLHLQWTVHNLPYHQELKMVFQIQISRIETSNVIWVGNYSTTV 89
+P TP L +S + + +L+L+W + ++++I++ R E+ ++ + ++TT+
Sbjct: 135 IPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTL 194
Query: 90 KWNQVLH-WSWESELPLECATHFVRIKSLVDDAKFPEPNFWSNWSSWEEVS-VQDSTGQD 147
LH WSW S++PLECA HFV I+ +D+ F WS+WS + +S + DS +
Sbjct: 195 NGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTK- 253
Query: 148 ILFVFPKDKLVEEGTNVTICYVSRN-----IQNNVSCYLEGKQIHGEQLDPHVTAFNLNS 202
VFP+DK++ G+++T C VS+ + + +C L IH LD A + +
Sbjct: 254 ---VFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPL----IH---LDGENVAIKIRN 303
Query: 203 VPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTD 262
+ + GTN+ + + G V+F + P+ +CET D K + C+W+PG
Sbjct: 304 ISVSASSGTNVVF-----TTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRV 358
Query: 263 TALGWSKQPSQSYTLFESFSGE------KKLCTHKNWCNWQITQDSQETYNFTLIAENYL 316
TAL + + SYTL ESFSG+ + T++++ +QE YNFTL A N L
Sbjct: 359 TALVGPR--ATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPL 416
Query: 317 RKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRNNFTYLCQIELHGEGKM 376
+ IL N+T +VY P S +++N+T ++W + +LC+IE+ +
Sbjct: 417 GRSQSTILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSV 476
Query: 377 M-QYNVSIK--VNGEYF--LSELEPATEYMARVRCADASHFWKWSEWSGQN-FTTLEAAP 430
Q NV+IK N Y L +L P T Y R+RC+ + FWKWS+WS + T EA+P
Sbjct: 477 QEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTET-FWKWSKWSNKKQHLTTEASP 535
Query: 431 SEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPA 490
S+ PD WR S + N + ++WKPL ANGKIL YNV + ++ S L IP P
Sbjct: 536 SKGPDTWREWSSDGKN--LIIYWKPLPINEANGKILSYNVSCSSDEETQS--LSEIPDPQ 591
Query: 491 NSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQ 550
+ ++ LD+ Y I V+A NSVG+SP S I S + N +++ E++ G G L+W
Sbjct: 592 HKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-SMEIPNDDLKIEQVVGMGKGILLTWHYD 650
Query: 551 PGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIA 610
P YV+ WC+ ++ W+ V N+T TVI +D FRPG+RY+F +YG +
Sbjct: 651 PNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQ 710
Query: 611 CLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQ 670
LL GY +ELAP P+ V+ ++ S + W+D E GF++GY Y R
Sbjct: 711 -LLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERD 769
Query: 671 CHPRFEKAVLSDGSECCKYK-IDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFT 729
+ VL G K K I + +K L + +L+ ++ Y + +T G GP +
Sbjct: 770 TS---KMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSM- 825
Query: 730 KVTTPDEHSSMLIHILLPMVFCVL---LIMVMCYLKSQWIKETCYPDIPDPYKSSILSLI 786
V T + ++I IL+P+ V+ + ++CY K +WIKET YPDIP+P L
Sbjct: 826 YVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQ 885
Query: 787 K--FKENPHLIIMNVSDCIPDAIEVV 810
K + + L + ++ C P+ +EV+
Sbjct: 886 KSVCEGSSALKTLEMNPCTPNNVEVL 911
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 411 bits (1056), Expect = e-114
Identities = 264/806 (32%), Positives = 421/806 (52%), Gaps = 54/806 (6%)
Query: 30 LPLTPVSLKVSTNSTRQSLHLQWTVHNLPYHQELKMVFQIQISRIETSNVIWVGNYSTTV 89
+P TP L +S + + +L+L+W + ++++I++ R E+ ++ + ++TT+
Sbjct: 135 IPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTL 194
Query: 90 KWNQVLH-WSWESELPLECATHFVRIKSLVDDAKFPEPNFWSNWSSWEEVS-VQDSTGQD 147
LH WSW S++PLECA HFV I+ +D+ F WS+WS + +S + DS +
Sbjct: 195 NGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTK- 253
Query: 148 ILFVFPKDKLVEEGTNVTICYVSRN-----IQNNVSCYLEGKQIHGEQLDPHVTAFNLNS 202
VFP+DK++ G+++T C VS+ + + +C L IH LD A + +
Sbjct: 254 ---VFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPL----IH---LDGENVAIKIRN 303
Query: 203 VPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTD 262
+ + GTN+ + + G V+F + P+ +CET D K + C+W+PG
Sbjct: 304 ISVSASSGTNVVF-----TTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRV 358
Query: 263 TALGWSKQPSQSYTLFESFSGE------KKLCTHKNWCNWQITQDSQETYNFTLIAENYL 316
TAL + + SYTL ESFSG+ + T++++ +QE YNFTL A N L
Sbjct: 359 TALVGPR--ATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPL 416
Query: 317 RKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRNNFTYLCQIELHGEGKM 376
+ IL N+T +VY P S +++N+T ++W + +LC+IE+ +
Sbjct: 417 GRSQSTILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSV 476
Query: 377 M-QYNVSIK--VNGEYF--LSELEPATEYMARVRCADASHFWKWSEWSGQN-FTTLEAAP 430
Q NV+IK N Y L +L P T Y R+RC+ + FWKWS+WS + T EA+P
Sbjct: 477 QEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTET-FWKWSKWSNKKQHLTTEASP 535
Query: 431 SEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPA 490
S+ PD WR S + N + ++WKPL ANGKIL YNV + ++ S L IP P
Sbjct: 536 SKGPDTWREWSSDGKN--LIIYWKPLPINEANGKILSYNVSCSSDEETQS--LSEIPDPQ 591
Query: 491 NSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQ 550
+ ++ LD+ Y I V+A NSVG+SP S I S + N +++ E++ G G L+W
Sbjct: 592 HKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-SMEIPNDDLKIEQVVGMGKGILLTWHYD 650
Query: 551 PGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIA 610
P YV+ WC+ ++ W+ V N+T TVI +D FRPG+RY+F +YG +
Sbjct: 651 PNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQ 710
Query: 611 CLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQ 670
LL GY +ELAP P+ V+ ++ S + W+D E GF++GY Y R
Sbjct: 711 -LLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERD 769
Query: 671 CHPRFEKAVLSDGSECCKYK-IDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFT 729
+ VL G K K I + +K L + +L+ ++ Y + +T G GP +
Sbjct: 770 TS---KMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSM- 825
Query: 730 KVTTPDEHSSMLIHILLPMVFCVL---LIMVMCYLKSQWIKETCYPDIPDPYKSSILSLI 786
V T + ++I IL+P+ V+ + ++CY K +WIKET YPDIP+P L
Sbjct: 826 YVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQ 885
Query: 787 K--FKENPHLIIMNVSDCIPDAIEVV 810
K + + L + ++ C P+ +EV+
Sbjct: 886 KSVCEGSSALKTLEMNPCTPNNVEVL 911
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 137 bits (346), Expect = 4e-32
Identities = 158/639 (24%), Positives = 267/639 (41%), Gaps = 90/639 (14%)
Query: 187 HGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSE-GMKGIVLFVSKVLEEPKDFSC 245
HG L+ VT L + F+ C+ + N E + G +FV E+P++ SC
Sbjct: 81 HGHSLNSQVTGLPLGTTLFV--------CKLACINSDEIQICGAEIFVGVAPEQPQNLSC 132
Query: 246 -ETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKN----WCNW---- 296
+ + T+ CTW+ G DT L YTL SG K L K +C++
Sbjct: 133 IQKGEQGTVACTWERGRDTHL------YTEYTL--QLSGPKNLTWQKQCKDIYCDYLDFG 184
Query: 297 -QITQDSQETYNFT--LIAENYL-RKRSVNILFNLTHRVYLMNPFSVN--FENVNATNAI 350
+T +S E+ NFT + A N L S+ F V + P+ + F+ + +
Sbjct: 185 INLTPESPES-NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCT 243
Query: 351 MTWKVHSIRNNFTYLCQIELHGEGKMMQYNVSI-KVNGEYFLSELEPATEYMARVRCADA 409
+ W+ + L ++ + V++ K G + L +L+P TEY ++ +
Sbjct: 244 LYWRDEGL----VLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQI--SSK 297
Query: 410 SHFWK--WSEWSGQ-NFTTLEAAPSEAPDVWRIVS-LEPGNHTVTLFWKPLSKLHANGKI 465
H +K WS+WS T E P+ DVW + ++ ++LFWK LS A GKI
Sbjct: 298 LHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKI 357
Query: 466 LFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGAS-PASVIVISA 524
L Y V ++ L + +I + T +I ++ + V A NS G+S P + +++
Sbjct: 358 LHYQVTLQELTG-GKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNL 416
Query: 525 DPENKEVEEERIAGTEG--GFSLSWKP---QPGDVIGYVVDWCDHTQ--DVLGDFQWKNV 577
+ A +EG ++W+P P V YVV+W + D W
Sbjct: 417 CEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRS 476
Query: 578 GPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLT 637
P S +IS + + + Y+ R+Y LS + C G S+ AP PH+ T
Sbjct: 477 RPYNVSALISEN-IKSYICYEIRVYALSGDQGGC--SSILGNSKHKAPLSGPHINAITEE 533
Query: 638 SHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEK 697
S +SW + Q G + Y +Y K + P+ + Y++ +
Sbjct: 534 KGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCE---------IPYRV---SQN 581
Query: 698 ALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMV 757
+ +++L+P Y ++T T+AGE + + + M + P + C+ +IMV
Sbjct: 582 SHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMA--FVAPSI-CIAIIMV 638
Query: 758 ---------------MCYLKSQWIKETCYPDIPDPYKSS 781
+ L+ QW C +IPDP S+
Sbjct: 639 GIFSTHYFQQKVFVLLAALRPQW----CSREIPDPANST 673
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 135 bits (341), Expect = 1e-31
Identities = 140/587 (23%), Positives = 232/587 (39%), Gaps = 56/587 (9%)
Query: 220 GNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFE 279
G + + + GI + E+PK+ SC + K + C WD G +T L ++TL
Sbjct: 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL------ETNFTLKS 162
Query: 280 SFSGEKKL-CTHKNWCNWQITQDSQETY----NFTLIAENYLRK-RSVNILFNLTHRVYL 333
++ K C K T D Y + AEN L K S +I F+ ++V
Sbjct: 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
Query: 334 MNPFSVNFENVNATNAI--MTWKVHSIRNNFTYLCQIELHGEGKMMQYNV----SIKVNG 387
P +++ N ++I +TW SI++ I+ + + +
Sbjct: 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQ-NFTTLEAAPSEAPDVWRIV--SLEP 444
+ + +L+P TEY+ R+RC WS+WS + + T E PS+AP W + S
Sbjct: 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
Query: 445 GNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQI 504
G TV L WK L ANGKIL Y V + S L + A + L Y
Sbjct: 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRW----KSHLQNYTVNATKLTVNLTNDRYLA 398
Query: 505 CVIANNSVGASPASVIVISA--DPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWC 562
+ N VG S A+V+ I A V + + + + W V Y+++WC
Sbjct: 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
Query: 563 DHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIAC----LLEKKTG 618
+ W+ T + G + + Y ++ + E
Sbjct: 459 VLSDKAPCITDWQQEDGTVHRTYLR------GNLAESKCYLITVTPVYADGPGSPESIKA 512
Query: 619 YSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKA 678
Y ++ PS P V + + L W + Q GFI+ Y ++ ++ E A
Sbjct: 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-----ETA 567
Query: 679 VLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAG--EGPSATFTKVT-TPD 735
V D S + +L ++ Y + +T G +GP TFT
Sbjct: 568 VNVDSS-----------HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
Query: 736 EHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKSSI 782
E ++++ + L + LL ++ C+ K IK+ +P++PDP KS I
Sbjct: 617 EIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 111 bits (277), Expect = 4e-24
Identities = 131/580 (22%), Positives = 235/580 (40%), Gaps = 74/580 (12%)
Query: 239 EPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFS-GEKKLCTHKNWCNWQ 297
+P++ SC K L CTW PG +T+ YT+ +++ GEK H N
Sbjct: 56 KPENISCVYYYRKNLTCTWSPGKETSY-------TQYTVKRTYAFGEK----HDNCTTNS 104
Query: 298 ITQDSQETYNFTL----IAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTW 353
T +++ + +F L I +NY ++ + V + EN+ T +
Sbjct: 105 STSENRASCSFFLPRITIPDNY----TIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIF 160
Query: 354 KVHSI-------------------RNNFTYLCQIELHGEGKMMQYNVSIK---VNGEYFL 391
+V + ++ Y + M+ N + N Y L
Sbjct: 161 RVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNL 220
Query: 392 SELEPATEYMARVRCA-DASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIV--SLEPGNHT 448
+ L+P TEY+ +RCA S FW S+WS + E ++WR++ + G
Sbjct: 221 TGLQPFTEYVIALRCAVKESKFW--SDWSQEKMGMTEEEAPCGLELWRVLKPAEADGRRP 278
Query: 449 VTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIA 508
V L WK K L YN+ + +E ++ +L L S+ + +I+
Sbjct: 279 VRLLWKKARGAPVLEKTLGYNIWYYPESNTNLTE--TMNTTNQQLELHLGGESFWVSMIS 336
Query: 509 NNSVGASPASVIVISADPENKE--VEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQ 566
NS+G SP + + I A E +E + E + W+ DV ++++W
Sbjct: 337 YNSLGKSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQSSALDVNTWMIEWFPDVD 396
Query: 567 DVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPS 626
W++V T T I D +P Y+ +Y + ++ + Y++E PS
Sbjct: 397 SEPTTLSWESVSQATNWT-IQQDKLKPFWCYNISVYPMLHDKVGEPYSIQA-YAKEGVPS 454
Query: 627 DNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSEC 686
+ P V+ + + T++WK+ + G I Y ++ +++ + F K V S
Sbjct: 455 EGPETKVENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGK---GFSKTV---NSSI 508
Query: 687 CKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAG--EGPSATFTKVTTPDEHSSMLIHI 744
+Y + ++LK ++ Y + TSAG G S F K + +LI
Sbjct: 509 LQYGL----------ESLKRKTSYIVQVMASTSAGGTNGTSINF-KTLSFSVFEIILITS 557
Query: 745 LLPMVFCVLLIMVMCY--LKSQWIKETCYPDIPDPYKSSI 782
L+ +L+I+ + Y K + C+P +P+P +SSI
Sbjct: 558 LIGGGLLILIILTVAYGLKKPNKLTHLCWPTVPNPAESSI 597
>gi|27437045 colony stimulating factor 3 receptor isoform d
precursor [Homo sapiens]
Length = 783
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/412 (24%), Positives = 163/412 (39%), Gaps = 41/412 (9%)
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQ-NFTTLEAAPSEAPDVW-RIVSLEPG 445
+Y L L PAT Y ++RC WS+WS T E AP+ D W R L+P
Sbjct: 291 QYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDP- 349
Query: 446 NHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLI----LDRCS 501
TV LFWKP+ +G+I Y V +PS +P N+T+L L +
Sbjct: 350 -RTVQLFWKPVPLEEDSGRIQGYVVSW----RPSGQAGAILPL-CNTTELSCTFHLPSEA 403
Query: 502 YQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDW 561
++ ++A NS G S + +V S +A + W+P GYV++W
Sbjct: 404 QEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEW 463
Query: 562 CDHTQDVLGDFQ-WKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYS 620
+ W+ + + + RP Y+ + L + + YS
Sbjct: 464 GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPS-QHVYAYS 522
Query: 621 QELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVL 680
QE+APS P + + + L W E + Y ++ + Q A+L
Sbjct: 523 QEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSF----SAIL 578
Query: 681 SDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSM 740
N + ++ L+P S Y + + AG S T +T E S
Sbjct: 579 ------------NASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSE- 625
Query: 741 LIHILLPMVFCVLLIMVMCYLKSQWI------KETCYPDIPDPYKSSILSLI 786
+HI+L + LL+++ C + W+ K +P +PDP SS+ S +
Sbjct: 626 -LHIILGLF--GLLLLLTCLCGTAWLCCSPNRKNPLWPSVPDPAHSSLGSWV 674
>gi|24496783 colony stimulating factor 3 receptor isoform c
precursor [Homo sapiens]
Length = 863
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/412 (24%), Positives = 163/412 (39%), Gaps = 41/412 (9%)
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQ-NFTTLEAAPSEAPDVW-RIVSLEPG 445
+Y L L PAT Y ++RC WS+WS T E AP+ D W R L+P
Sbjct: 291 QYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDP- 349
Query: 446 NHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLI----LDRCS 501
TV LFWKP+ +G+I Y V +PS +P N+T+L L +
Sbjct: 350 -RTVQLFWKPVPLEEDSGRIQGYVVSW----RPSGQAGAILPL-CNTTELSCTFHLPSEA 403
Query: 502 YQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDW 561
++ ++A NS G S + +V S +A + W+P GYV++W
Sbjct: 404 QEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEW 463
Query: 562 CDHTQDVLGDFQ-WKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYS 620
+ W+ + + + RP Y+ + L + + YS
Sbjct: 464 GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPS-QHVYAYS 522
Query: 621 QELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVL 680
QE+APS P + + + L W E + Y ++ + Q A+L
Sbjct: 523 QEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSF----SAIL 578
Query: 681 SDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSM 740
N + ++ L+P S Y + + AG S T +T E S
Sbjct: 579 ------------NASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSE- 625
Query: 741 LIHILLPMVFCVLLIMVMCYLKSQWI------KETCYPDIPDPYKSSILSLI 786
+HI+L + LL+++ C + W+ K +P +PDP SS+ S +
Sbjct: 626 -LHIILGLF--GLLLLLTCLCGTAWLCCSPNRKNPLWPSVPDPAHSSLGSWV 674
>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
[Homo sapiens]
Length = 836
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/412 (24%), Positives = 163/412 (39%), Gaps = 41/412 (9%)
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQ-NFTTLEAAPSEAPDVW-RIVSLEPG 445
+Y L L PAT Y ++RC WS+WS T E AP+ D W R L+P
Sbjct: 291 QYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDP- 349
Query: 446 NHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLI----LDRCS 501
TV LFWKP+ +G+I Y V +PS +P N+T+L L +
Sbjct: 350 -RTVQLFWKPVPLEEDSGRIQGYVVSW----RPSGQAGAILPL-CNTTELSCTFHLPSEA 403
Query: 502 YQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDW 561
++ ++A NS G S + +V S +A + W+P GYV++W
Sbjct: 404 QEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEW 463
Query: 562 CDHTQDVLGDFQ-WKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYS 620
+ W+ + + + RP Y+ + L + + YS
Sbjct: 464 GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPS-QHVYAYS 522
Query: 621 QELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVL 680
QE+APS P + + + L W E + Y ++ + Q A+L
Sbjct: 523 QEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSF----SAIL 578
Query: 681 SDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSM 740
N + ++ L+P S Y + + AG S T +T E S
Sbjct: 579 ------------NASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSE- 625
Query: 741 LIHILLPMVFCVLLIMVMCYLKSQWI------KETCYPDIPDPYKSSILSLI 786
+HI+L + LL+++ C + W+ K +P +PDP SS+ S +
Sbjct: 626 -LHIILGLF--GLLLLLTCLCGTAWLCCSPNRKNPLWPSVPDPAHSSLGSWV 674
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 73.2 bits (178), Expect = 1e-12
Identities = 84/352 (23%), Positives = 134/352 (38%), Gaps = 31/352 (8%)
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQ-NFTTLEAAPSEAPDVW-RIVSLEPG 445
+Y L L PAT Y ++RC WS+WS T E AP+ D W R L+P
Sbjct: 291 QYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDP- 349
Query: 446 NHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLI----LDRCS 501
TV LFWKP+ +G+I Y V +PS +P N+T+L L +
Sbjct: 350 -RTVQLFWKPVPLEEDSGRIQGYVVSW----RPSGQAGAILPL-CNTTELSCTFHLPSEA 403
Query: 502 YQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDW 561
++ ++A NS G S + +V S +A + W+P GYV++W
Sbjct: 404 QEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEW 463
Query: 562 -CDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYS 620
+ W+ + + + RP Y+ + L + + YS
Sbjct: 464 GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMG-PSQHVYAYS 522
Query: 621 QELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVL 680
QE+APS P + + + L W E + Y ++ + Q A+L
Sbjct: 523 QEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSF----SAIL 578
Query: 681 SDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVT 732
N + ++ L+P S Y + + AG S T +T
Sbjct: 579 ------------NASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMT 618
>gi|4759328 class I cytokine receptor [Homo sapiens]
Length = 636
Score = 64.7 bits (156), Expect = 4e-10
Identities = 90/409 (22%), Positives = 157/409 (38%), Gaps = 54/409 (13%)
Query: 391 LSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSL--EPGNHT 448
+ +LE AT Y RC W EWS + + PS DVW +L PG
Sbjct: 193 IQDLELATGYKVYGRCRMEKEEDLWGEWSP--ILSFQTPPSAPKDVWVSGNLCGTPGGEE 250
Query: 449 VTLFWK-PLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVI 507
L WK P + + K+ F+ E + + IP+ A + V
Sbjct: 251 PLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWAR-----------VS 299
Query: 508 ANNSVGASPA---SVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDH 564
A N+ P S++ + + + V IAG+ ++W+P PG+ + +VVDW
Sbjct: 300 AVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTE-LLVTWQPGPGEPLEHVVDWA-R 357
Query: 565 TQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELA 624
D L W + P S ++ + F GV Y + +S +A G+ +ELA
Sbjct: 358 DGDPLEKLNWVRLPPGNLSALLPGN-FTVGVPYRITVTAVSASGLAS-ASSVWGFREELA 415
Query: 625 PSDNPHV-LVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDG 683
P P + + + ++W + G + Y + +S +
Sbjct: 416 PLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSG-------------TSP 462
Query: 684 SECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIH 743
S C + + + D P E ++T T AG+GP ++ PD +++
Sbjct: 463 SVC--MNVSGNTQSVTLPD--LPWGPCELWVTASTIAGQGPPGPILRLHLPD--NTLRWK 516
Query: 744 ILLPMVFCVLLIMVMC-----------YLKSQWIKETCYPDIPDPYKSS 781
+L ++F L ++ C +L+ + + + +PDP SS
Sbjct: 517 VLPGILFLWGLFLLGCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSS 565
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 62.4 bits (150), Expect = 2e-09
Identities = 113/517 (21%), Positives = 198/517 (38%), Gaps = 60/517 (11%)
Query: 126 PNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLE--- 182
P WS+WS+ + QD + FP L G+NV+ + + +N + E
Sbjct: 316 PGIWSDWSTPRVFTTQD------VIYFPPKILTSVGSNVSFHCIYKK-ENKIVPSKEIVW 368
Query: 183 ----GKQIHGEQLD------PHVTAFNLNSVPFIRNKGTN--IYCEASQGNVSEGMKGIV 230
++I Q D VT FNLN R K T +YC ++ +
Sbjct: 369 WMNLAEKIPQSQYDVVSDHVSKVTFFNLNETK-PRGKFTYDAVYC-CNEHECHHRYAELY 426
Query: 231 LFVSKVLEEPKDFSCETEDFKT-LHCTWDPGTDTALGWSKQPSQSY--TLFESFSGEKKL 287
V++ + SCET+ + T + C W T +L S + + +L+ S
Sbjct: 427 -----VIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481
Query: 288 CTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHR----------VYLMNPF 337
+ C Q + + + Y +N V + P
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPS 541
Query: 338 SVNFE-NVNATNAIMTWKVHSI-RNNFTYLCQIELHG-EGKMMQYNVSIKVNGEYFLSEL 394
SV E +N ++W+ NN + + L G E + Y V + L
Sbjct: 542 SVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVP 601
Query: 395 EPATEYMARVRCADASHFWKWSEWSGQNFTTLE--AAPSEAPDVWRIVSLE--PGNHTVT 450
+ Y +VRC WS WS +T + P P+ WRI++ + VT
Sbjct: 602 DLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVT 661
Query: 451 LFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANN 510
L WKPL K + + Y V+ + + + + T L ++ ++ + V+A N
Sbjct: 662 LLWKPLMKNDSLCSVQRY--VINHHTSCNGTWSEDVGNHTKFTFLWTEQ-AHTVTVLAIN 718
Query: 511 SVGASPASVIVISADPENKEVEEERIAGTEGGFS---LSWKPQPGD--VIGYVVDWCDHT 565
S+GAS A+ + + P +K + ++ S +SW P D ++ ++++W +
Sbjct: 719 SIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLN 778
Query: 566 QDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIY 602
+D G+ +W + + I D F P +Y F +Y
Sbjct: 779 ED--GEIKWLRISSSVKKYYIH-DHFIPIEKYQFSLY 812
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 62.4 bits (150), Expect = 2e-09
Identities = 113/517 (21%), Positives = 198/517 (38%), Gaps = 60/517 (11%)
Query: 126 PNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLE--- 182
P WS+WS+ + QD + FP L G+NV+ + + +N + E
Sbjct: 316 PGIWSDWSTPRVFTTQD------VIYFPPKILTSVGSNVSFHCIYKK-ENKIVPSKEIVW 368
Query: 183 ----GKQIHGEQLD------PHVTAFNLNSVPFIRNKGTN--IYCEASQGNVSEGMKGIV 230
++I Q D VT FNLN R K T +YC ++ +
Sbjct: 369 WMNLAEKIPQSQYDVVSDHVSKVTFFNLNETK-PRGKFTYDAVYC-CNEHECHHRYAELY 426
Query: 231 LFVSKVLEEPKDFSCETEDFKT-LHCTWDPGTDTALGWSKQPSQSY--TLFESFSGEKKL 287
V++ + SCET+ + T + C W T +L S + + +L+ S
Sbjct: 427 -----VIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481
Query: 288 CTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHR----------VYLMNPF 337
+ C Q + + + Y +N V + P
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPS 541
Query: 338 SVNFE-NVNATNAIMTWKVHSI-RNNFTYLCQIELHG-EGKMMQYNVSIKVNGEYFLSEL 394
SV E +N ++W+ NN + + L G E + Y V + L
Sbjct: 542 SVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVP 601
Query: 395 EPATEYMARVRCADASHFWKWSEWSGQNFTTLE--AAPSEAPDVWRIVSLE--PGNHTVT 450
+ Y +VRC WS WS +T + P P+ WRI++ + VT
Sbjct: 602 DLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVT 661
Query: 451 LFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANN 510
L WKPL K + + Y V+ + + + + T L ++ ++ + V+A N
Sbjct: 662 LLWKPLMKNDSLCSVQRY--VINHHTSCNGTWSEDVGNHTKFTFLWTEQ-AHTVTVLAIN 718
Query: 511 SVGASPASVIVISADPENKEVEEERIAGTEGGFS---LSWKPQPGD--VIGYVVDWCDHT 565
S+GAS A+ + + P +K + ++ S +SW P D ++ ++++W +
Sbjct: 719 SIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLN 778
Query: 566 QDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIY 602
+D G+ +W + + I D F P +Y F +Y
Sbjct: 779 ED--GEIKWLRISSSVKKYYIH-DHFIPIEKYQFSLY 812
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 62.4 bits (150), Expect = 2e-09
Identities = 113/517 (21%), Positives = 198/517 (38%), Gaps = 60/517 (11%)
Query: 126 PNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLE--- 182
P WS+WS+ + QD + FP L G+NV+ + + +N + E
Sbjct: 316 PGIWSDWSTPRVFTTQD------VIYFPPKILTSVGSNVSFHCIYKK-ENKIVPSKEIVW 368
Query: 183 ----GKQIHGEQLD------PHVTAFNLNSVPFIRNKGTN--IYCEASQGNVSEGMKGIV 230
++I Q D VT FNLN R K T +YC ++ +
Sbjct: 369 WMNLAEKIPQSQYDVVSDHVSKVTFFNLNETK-PRGKFTYDAVYC-CNEHECHHRYAELY 426
Query: 231 LFVSKVLEEPKDFSCETEDFKT-LHCTWDPGTDTALGWSKQPSQSY--TLFESFSGEKKL 287
V++ + SCET+ + T + C W T +L S + + +L+ S
Sbjct: 427 -----VIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481
Query: 288 CTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHR----------VYLMNPF 337
+ C Q + + + Y +N V + P
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPS 541
Query: 338 SVNFE-NVNATNAIMTWKVHSI-RNNFTYLCQIELHG-EGKMMQYNVSIKVNGEYFLSEL 394
SV E +N ++W+ NN + + L G E + Y V + L
Sbjct: 542 SVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVP 601
Query: 395 EPATEYMARVRCADASHFWKWSEWSGQNFTTLE--AAPSEAPDVWRIVSLE--PGNHTVT 450
+ Y +VRC WS WS +T + P P+ WRI++ + VT
Sbjct: 602 DLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVT 661
Query: 451 LFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANN 510
L WKPL K + + Y V+ + + + + T L ++ ++ + V+A N
Sbjct: 662 LLWKPLMKNDSLCSVQRY--VINHHTSCNGTWSEDVGNHTKFTFLWTEQ-AHTVTVLAIN 718
Query: 511 SVGASPASVIVISADPENKEVEEERIAGTEGGFS---LSWKPQPGD--VIGYVVDWCDHT 565
S+GAS A+ + + P +K + ++ S +SW P D ++ ++++W +
Sbjct: 719 SIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLN 778
Query: 566 QDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIY 602
+D G+ +W + + I D F P +Y F +Y
Sbjct: 779 ED--GEIKWLRISSSVKKYYIH-DHFIPIEKYQFSLY 812
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 58.5 bits (140), Expect = 3e-08
Identities = 52/212 (24%), Positives = 89/212 (41%), Gaps = 18/212 (8%)
Query: 220 GNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFE 279
G + + + GI + E+PK+ SC + K + C WD G +T L ++TL
Sbjct: 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL------ETNFTLKS 162
Query: 280 SFSGEKKL-CTHKNWCNWQITQDSQETY----NFTLIAENYLRK-RSVNILFNLTHRVYL 333
++ K C K T D Y + AEN L K S +I F+ ++V
Sbjct: 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
Query: 334 MNPFSVNFENVNATNAI--MTWKVHSIRNNFTYLCQIELHGEGKMMQYNV----SIKVNG 387
P +++ N ++I +TW SI++ I+ + + +
Sbjct: 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWS 419
+ + +L+P TEY+ R+RC WS+WS
Sbjct: 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 57.4 bits (137), Expect = 6e-08
Identities = 87/367 (23%), Positives = 153/367 (41%), Gaps = 41/367 (11%)
Query: 375 KMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWS--GQNFTTLEAAPSE 432
+M +Y VS K GE +S L+ + VR + S F+ + G++ ++ E
Sbjct: 831 EMARYLVSTKEVGEEVISTLQ----ILPTVR--EDSGFFSCHAINSYGEDRGIIQLTVQE 884
Query: 433 APDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENL-DKPSSSELHSIPAPAN 491
PD I + T+TL W N I Y++ +N D S++ +P
Sbjct: 885 PPDPPEIEIKDVKARTITLRWT--MGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQL 942
Query: 492 STKLILD---RCSYQICVIANNSVGAS-PASVIVISAD---PENKEVEEERIAGTEGGFS 544
++ I+D +Y I + A N +G S P++ + I+AD P+ E +
Sbjct: 943 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIR 1002
Query: 545 LSWKP-----QPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTT--STVISTDAFRPGVRY 597
++WK Q G + GY + + +++ G+FQ+ + +T+ S V + D +Y
Sbjct: 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTG--GNFQFNIISVDTSGDSEVYTLDNLNKFTQY 1060
Query: 598 DFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTS-HSFTLSWKDYSTESQPGF 656
+ + ++ + E PS P + TS S ++SW S E+ G
Sbjct: 1061 GLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGI 1120
Query: 657 IQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITP 716
+QG+ V A L DG E + K + +L +D L+ + Y +
Sbjct: 1121 LQGFRV------------IYWANLMDG-ELGEIKNITTTQPSLELDGLEKYTNYSIQVLA 1167
Query: 717 FTSAGEG 723
FT AG+G
Sbjct: 1168 FTRAGDG 1174
Score = 42.7 bits (99), Expect = 0.002
Identities = 75/369 (20%), Positives = 129/369 (34%), Gaps = 44/369 (11%)
Query: 380 NVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRI 439
+VS ++N + ++ P++ Y R+ + K + T EAAP P
Sbjct: 937 DVSPQLNSATII-DIHPSSTYSIRMYAKN--RIGKSEPSNELTITADEAAPDGPPQE--- 990
Query: 440 VSLEP-GNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELH--SIPAPANSTKLI 496
V LEP + ++ + WK K NG I Y + + + + S+ +S
Sbjct: 991 VHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYT 1050
Query: 497 LDRCS----YQICVIANNSVGASPASVIVISAD----PENKEVEEERIAGTEGGFSLSWK 548
LD + Y + V A N G P+S +I+ P + IA + S+SW
Sbjct: 1051 LDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWS 1110
Query: 549 PQPGDVIG------YVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIY 602
+ + V+ W + LG+ KN+ TT + D Y ++
Sbjct: 1111 TLSKEALNGILQGFRVIYWANLMDGELGEI--KNI--TTTQPSLELDGLEKYTNYSIQVL 1166
Query: 603 GLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHV 662
+ E+ ++E P V ++ +SW G I+ Y V
Sbjct: 1167 AFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTV 1224
Query: 663 YLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGE 722
+ FE + P+ + + NL Y ++ TSAG
Sbjct: 1225 FCSHPYPTVISEFEAS---------------PDSFSYRIPNLSRNRQYSVWVVAVTSAGR 1269
Query: 723 GPSATFTKV 731
G S+ V
Sbjct: 1270 GNSSEIITV 1278
Score = 39.3 bits (90), Expect = 0.018
Identities = 51/235 (21%), Positives = 89/235 (37%), Gaps = 21/235 (8%)
Query: 508 ANNSVGASPASV-IVISADPENKEVEEERIAGTEGGFSLSWK---PQPGDVIGYVVDWCD 563
A NS G + + + P+ E+E + + +L W + GY ++ C
Sbjct: 867 AINSYGEDRGIIQLTVQEPPDPPEIEIKDVKART--ITLRWTMGFDGNSPITGYDIE-CK 923
Query: 564 HTQDVLGDFQ-WKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQE 622
+ D Q K+V P S I P Y R+Y + + + T + E
Sbjct: 924 NKSDSWDSAQRTKDVSPQLNSATIID--IHPSSTYSIRMYAKNRIGKSEPSNELTITADE 981
Query: 623 LAPSDNPH-VLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLS 681
AP P V ++ ++S S ++WK Q G I+GY + + + + +F +
Sbjct: 982 AAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVD 1041
Query: 682 DGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDE 736
+ Y + DNL + Y + AG GPS+ TT ++
Sbjct: 1042 TSGDSEVYTL----------DNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLED 1086
Score = 37.7 bits (86), Expect = 0.053
Identities = 69/288 (23%), Positives = 102/288 (35%), Gaps = 45/288 (15%)
Query: 449 VTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRC-SYQICVI 507
V + W P KL NG I Y V + SE + P + L R Y + V+
Sbjct: 1205 VFVSWLPPLKL--NGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVV 1262
Query: 508 ANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQD 567
A S G +S I I+ +P K RI G + W +V C D
Sbjct: 1263 AVTSAGRGNSSEI-ITVEPLAKA--PARILTFSGTVTTPWMKD-------IVLPCKAVGD 1312
Query: 568 VLGDFQWKNVGPNTTSTVISTDA----FRPGVRYDFRIYGLSTKRIACLLEKKTGYSQEL 623
+W N T ++++ D F G + + +C+ G + +
Sbjct: 1313 PSPAVKWMK-DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEII 1371
Query: 624 ------APSDNPHVLVDTLTSHSFTLSW--KDYSTESQPGFIQGYHVYLKSKARQCHPRF 675
P D P + V TS S TLSW D S G+I Y
Sbjct: 1372 LNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS-------------- 1417
Query: 676 EKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEG 723
D SE +P E++ ++NLK ++Y+F +T G G
Sbjct: 1418 -----EDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPG 1460
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 55.8 bits (133), Expect = 2e-07
Identities = 92/437 (21%), Positives = 159/437 (36%), Gaps = 60/437 (13%)
Query: 336 PFSVNFENVNATNAIMTWKVHSIRNNFTYLCQIELHGEGKMMQYNVSIKVNG----EYFL 391
P + F V T+ + W+ + N QI H +++V +Y
Sbjct: 1304 PMGILFPEVRTTSVRLIWQPPAAPNGIILAYQIT-HRLNTTTANTATVEVLAPSARQYTA 1362
Query: 392 SELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGN-HTVT 450
+ L+P + Y+ R+ W E + T E P +V E +V
Sbjct: 1363 TGLKPESVYLFRITAQTRKG---WGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVL 1419
Query: 451 LFWKPLSKLHANGKILFYNVVVENLDKPSSS-ELHSIPAPANSTKLILDRC----SYQIC 505
L W+P S + +Y + L PS LHS N++ I+DR SY+
Sbjct: 1420 LSWEPGSD--GLSPVRYYTIQTREL--PSGRWALHSASVSHNASSFIVDRLKPFTSYKFR 1475
Query: 506 VIANNSVGASP-----ASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGD-----VI 555
V A N +G S S+ + A P+ T + W+P D ++
Sbjct: 1476 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 1535
Query: 556 GYVVDWCDHTQDVLGDFQWKNVG------PNTTSTVISTDAFRPGV------------RY 597
G+ + + + + L F + + TS + RP + RY
Sbjct: 1536 GFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRY 1595
Query: 598 DFRIYGLSTKRIACLLEKKTGYSQELAPSDNP-HVLVDTLTSHSFTLSWKDYSTESQPGF 656
+ R+ + + + E P+ P +V+V T+ ++W+ +SQ G
Sbjct: 1596 EIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGD 1655
Query: 657 IQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITP 716
IQGY +Y R G+ + K E ++ + NL + Y +
Sbjct: 1656 IQGYKIYFWEAQR-------------GNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
Query: 717 FTSAGEGPSATFTKVTT 733
F +AG+GP +T T+ T
Sbjct: 1703 FNAAGDGPRSTPTQGQT 1719
Score = 47.4 bits (111), Expect = 7e-05
Identities = 81/400 (20%), Positives = 143/400 (35%), Gaps = 64/400 (16%)
Query: 372 GEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPS 431
G GK + + V +V +Y + +LE TEY +V+ +A WS+ T E+ PS
Sbjct: 1143 GHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGR--TRESVPS 1200
Query: 432 EAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPAN 491
P + +L + ++ + W + + NG +L Y V+ + D + + ++
Sbjct: 1201 SGPT--NVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSS 1258
Query: 492 STKLIL---DRCSYQICVIANNSVG-ASPASVIVISADPENKEVEEERIAGTE---GGFS 544
+ + Y++ V+A +G SP+ ++ ++ I E
Sbjct: 1259 RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVR 1318
Query: 545 LSWKPQP---GDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVR----- 596
L W+P G ++ Y + +T TT+ + + P R
Sbjct: 1319 LIWQPPAAPNGIILAYQITHRLNT---------------TTANTATVEVLAPSARQYTAT 1363
Query: 597 -------YDFRIYGLSTK---RIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWK 646
Y FRI + K A L T P P V + + + S LSW+
Sbjct: 1364 GLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE 1423
Query: 647 DYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKP 706
S P ++ Y + + L G + + IVD LKP
Sbjct: 1424 PGSDGLSP--VRYYTIQTRE-------------LPSGRWALHSASVSHNASSFIVDRLKP 1468
Query: 707 ESFYEFFITPFTSAG-----EGPSATFTKVTTPDEHSSML 741
+ Y+F + G E + T PDE ++L
Sbjct: 1469 FTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTIL 1508
Score = 41.2 bits (95), Expect = 0.005
Identities = 63/317 (19%), Positives = 120/317 (37%), Gaps = 44/317 (13%)
Query: 449 VTLFW-KPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANST--KLILDRCSYQIC 505
+ L W KP N ++ Y + + + P + L S+ A S K ++ SYQ
Sbjct: 608 INLTWTKPFD---GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFR 664
Query: 506 VIANNSVGASPASV----IVISADPENKEVEEERIAG-TEGGFSLSWKPQP-----GDVI 555
+ A N VG S + + +P + +G T + W+P P G +
Sbjct: 665 LCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILK 724
Query: 556 GYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEK 615
GY++ +C V +Q+KN+ + ++ D Y+ + ++ + K
Sbjct: 725 GYIIRYCLAGLPV--GYQFKNITDADVNNLLLEDLII-WTNYEIEVAAYNSAGLGVYSSK 781
Query: 616 KTGYSQELAPSDNP-HVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQ---- 670
T ++ + P+ P +V + S + +W S + G QGY + ++
Sbjct: 782 VTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVT 841
Query: 671 ---CHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSAT 727
P F+ ++ V LK + Y + FT+ G+GP +T
Sbjct: 842 MVTARPNFQDSI-----------------HVGFVSGLKKFTEYFTSVLCFTTPGDGPRST 884
Query: 728 FTKVTTPDEHSSMLIHI 744
V T ++ + H+
Sbjct: 885 PQLVRTHEDVPGPVGHL 901
Score = 38.1 bits (87), Expect = 0.041
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 618 GYSQELAPSDNP-HVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFE 676
G ++E PS P +V TS S + W + + G + GY V K K PRF
Sbjct: 1192 GRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRF- 1250
Query: 677 KAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEG-PSATFTKVTTPD 735
+ ++ ++ + L YE + FT G+G PS T D
Sbjct: 1251 ------------WLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD 1298
Query: 736 EHSSMLIHILLPMV 749
+ + IL P V
Sbjct: 1299 DVPGPPMGILFPEV 1312
Score = 34.3 bits (77), Expect = 0.59
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 546 SWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRI---- 601
S P G + YV++ + + L D K++ +S S D +PGV YDFR+
Sbjct: 1846 SGDPGKGPITRYVIE-ARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVN 1904
Query: 602 -YGLST 606
YG T
Sbjct: 1905 DYGFGT 1910
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 54.7 bits (130), Expect = 4e-07
Identities = 75/355 (21%), Positives = 143/355 (40%), Gaps = 43/355 (12%)
Query: 336 PFSVNFENVNATNAIMTWKVHSIRN--NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSE 393
P + E + T+ +++W N+ + + HGE + ++I+ Y L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGE----EQRITIEPGTSYRLQG 574
Query: 394 LEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFW 453
L+P + Y R+ A S + + + T+++ PS P I P + ++ + W
Sbjct: 575 LKPNSLYYFRL--AARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSW 630
Query: 454 KPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDR----CSYQICVIAN 509
+P NG I Y++ +D + P+++TK +L++ Y+I V A+
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAH 690
Query: 510 NSVGASPASVIVISADPEN------KEVEEERIAGTEGGFSLSWK-----PQPGDVIGYV 558
VG P S+ V+ E+ ++VE E + T +SW+ Q G + GY
Sbjct: 691 TDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNST--SVKVSWRSPVPNKQHGQIRGYQ 748
Query: 559 VDWC----------DHTQDV-LGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTK 607
V + +DV L D QW+ +TT + +P Y + +TK
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWE--FDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 608 RIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHV 662
+ K + P P ++++ ++ + W + G +QGY +
Sbjct: 807 GDGARSKPKLVSTTGAVPG-KPRLVINHTQMNTALIQW--HPPVDTFGPLQGYRL 858
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 620 SQELAPSDNPH-VLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVY---LKSKARQCHPRF 675
+ E PS P V V+ + S S +SW+ Q G I+GY V+ +++ + P
Sbjct: 706 TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765
Query: 676 EKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTT 733
+ +L+D +++ D+ E +I+ L+PE+ Y +T +T+ G+G + V+T
Sbjct: 766 KDVMLADA----QWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVST 819
Score = 44.3 bits (103), Expect = 6e-04
Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 16/152 (10%)
Query: 583 STVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPH-VLVDTLTSHSF 641
+T S P Y+FR+ ++ E + E APS P V L+S +
Sbjct: 375 TTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTI 434
Query: 642 TLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIV 701
+ WK+ E G IQGY VY Q + K ++D + +
Sbjct: 435 LVQWKE--PEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADS-------------QITTI 479
Query: 702 DNLKPESFYEFFITPFTSAGEGPSATFTKVTT 733
NL P+ Y + FTS G+GP ++ +V T
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 511
Score = 31.2 bits (69), Expect = 5.0
Identities = 88/396 (22%), Positives = 135/396 (34%), Gaps = 59/396 (14%)
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNH 447
+Y L +LE TEY R+ + E T E PS P R V +E N
Sbjct: 671 KYLLEQLEKWTEY--RITVTAHTDVGPGPESLSVLIRTNEDVPSGPP---RKVEVEAVNS 725
Query: 448 T-VTLFWKPLSKLHANGKILFYNVV---VENLDKPSSSELHSIPAPANSTKL-------- 495
T V + W+ +G+I Y V +EN + L + +
Sbjct: 726 TSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDM 785
Query: 496 ----ILDRCSYQICVIANNSVG----ASPASVIVISADPENKEVEEERIAGTEGGFSL-S 546
+ SY + V A + G + P V A P + I T+ +L
Sbjct: 786 IISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLV---INHTQMNTALIQ 842
Query: 547 WKPQP---GDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDA---FRPGVRYDFR 600
W P G + GY + + + L ++ + T+T I A FR R
Sbjct: 843 WHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVG 902
Query: 601 IYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGY 660
K I+ E TG+ Q L TS S LSW+ + G I Y
Sbjct: 903 FGEEMVKEISIPEEVPTGFPQNLHSEGT--------TSTSVQLSWQPPVLAERNGIITKY 954
Query: 661 HVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSA 720
+ + P + V P + + + LKP++ Y+ + TS
Sbjct: 955 TLLYRDINIPLLPMEQLIV--------------PADTTMTLTGLKPDTTYDVKVRAHTSK 1000
Query: 721 GEGPSATFTKVTT--PDEHSSMLIHILLPMVFCVLL 754
G GP + + T D+ + H+ M VLL
Sbjct: 1001 GPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLL 1036
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 54.7 bits (130), Expect = 4e-07
Identities = 75/355 (21%), Positives = 143/355 (40%), Gaps = 43/355 (12%)
Query: 336 PFSVNFENVNATNAIMTWKVHSIRN--NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSE 393
P + E + T+ +++W N+ + + HGE + ++I+ Y L
Sbjct: 506 PLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGE----EQRITIEPGTSYRLQG 561
Query: 394 LEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFW 453
L+P + Y R+ A S + + + T+++ PS P I P + ++ + W
Sbjct: 562 LKPNSLYYFRL--AARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSW 617
Query: 454 KPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDR----CSYQICVIAN 509
+P NG I Y++ +D + P+++TK +L++ Y+I V A+
Sbjct: 618 QPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAH 677
Query: 510 NSVGASPASVIVISADPEN------KEVEEERIAGTEGGFSLSWK-----PQPGDVIGYV 558
VG P S+ V+ E+ ++VE E + T +SW+ Q G + GY
Sbjct: 678 TDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNST--SVKVSWRSPVPNKQHGQIRGYQ 735
Query: 559 VDWC----------DHTQDV-LGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTK 607
V + +DV L D QW+ +TT + +P Y + +TK
Sbjct: 736 VHYVRMENGEPKGQPMLKDVMLADAQWE--FDDTTEHDMIISGLQPETSYSLTVTAYTTK 793
Query: 608 RIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHV 662
+ K + P P ++++ ++ + W + G +QGY +
Sbjct: 794 GDGARSKPKLVSTTGAVPG-KPRLVINHTQMNTALIQW--HPPVDTFGPLQGYRL 845
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 620 SQELAPSDNPH-VLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVY---LKSKARQCHPRF 675
+ E PS P V V+ + S S +SW+ Q G I+GY V+ +++ + P
Sbjct: 693 TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 752
Query: 676 EKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTT 733
+ +L+D +++ D+ E +I+ L+PE+ Y +T +T+ G+G + V+T
Sbjct: 753 KDVMLADA----QWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVST 806
Score = 44.3 bits (103), Expect = 6e-04
Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 16/152 (10%)
Query: 583 STVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPH-VLVDTLTSHSF 641
+T S P Y+FR+ ++ E + E APS P V L+S +
Sbjct: 362 TTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTI 421
Query: 642 TLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIV 701
+ WK+ E G IQGY VY Q + K ++D + +
Sbjct: 422 LVQWKE--PEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADS-------------QITTI 466
Query: 702 DNLKPESFYEFFITPFTSAGEGPSATFTKVTT 733
NL P+ Y + FTS G+GP ++ +V T
Sbjct: 467 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 498
Score = 31.2 bits (69), Expect = 5.0
Identities = 88/396 (22%), Positives = 135/396 (34%), Gaps = 59/396 (14%)
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNH 447
+Y L +LE TEY R+ + E T E PS P R V +E N
Sbjct: 658 KYLLEQLEKWTEY--RITVTAHTDVGPGPESLSVLIRTNEDVPSGPP---RKVEVEAVNS 712
Query: 448 T-VTLFWKPLSKLHANGKILFYNVV---VENLDKPSSSELHSIPAPANSTKL-------- 495
T V + W+ +G+I Y V +EN + L + +
Sbjct: 713 TSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDM 772
Query: 496 ----ILDRCSYQICVIANNSVG----ASPASVIVISADPENKEVEEERIAGTEGGFSL-S 546
+ SY + V A + G + P V A P + I T+ +L
Sbjct: 773 IISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLV---INHTQMNTALIQ 829
Query: 547 WKPQP---GDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDA---FRPGVRYDFR 600
W P G + GY + + + L ++ + T+T I A FR R
Sbjct: 830 WHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVG 889
Query: 601 IYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGY 660
K I+ E TG+ Q L TS S LSW+ + G I Y
Sbjct: 890 FGEEMVKEISIPEEVPTGFPQNLHSEGT--------TSTSVQLSWQPPVLAERNGIITKY 941
Query: 661 HVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSA 720
+ + P + V P + + + LKP++ Y+ + TS
Sbjct: 942 TLLYRDINIPLLPMEQLIV--------------PADTTMTLTGLKPDTTYDVKVRAHTSK 987
Query: 721 GEGPSATFTKVTT--PDEHSSMLIHILLPMVFCVLL 754
G GP + + T D+ + H+ M VLL
Sbjct: 988 GPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLL 1023
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 53.5 bits (127), Expect = 9e-07
Identities = 72/304 (23%), Positives = 124/304 (40%), Gaps = 36/304 (11%)
Query: 449 VTLFWKPLSKLHANGKILFYNVVVENLDKPSSSE----LHSIPAPANSTKLILDR-CSYQ 503
V + W P N I Y++ E DK + E L +P ST L L Y
Sbjct: 626 VRVSWSPAED--HNAPIEKYDIEFE--DKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYT 681
Query: 504 ICVIANNSVGA---SPASVIVIS--ADPENKEVEEERIAGTEGGFSLSWKPQP-----GD 553
V A N G SP S V++ A PE V+ + ++WKP
Sbjct: 682 FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAP 741
Query: 554 VIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLL 613
+ Y V W Q G +Q + + + V +T F P Y+ ++ ++++
Sbjct: 742 QVQYRVQW--RPQGTRGPWQ-EQIVSDPFLVVSNTSTFVP---YEIKVQAVNSQGKGPEP 795
Query: 614 EKKTGYSQELAPSDNPHVL-VDTLTSHSFTLSWKDYSTESQPGFIQGYHV-YLKSKARQC 671
+ GYS E P P + ++ L S + + W+ G ++GY+V Y + +++
Sbjct: 796 QVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRK 855
Query: 672 HPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKV 731
H + + + D + + ++I+ L+P S Y + F G GP++ FT
Sbjct: 856 HSK--RHIHKD------HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFT-F 906
Query: 732 TTPD 735
+TP+
Sbjct: 907 STPE 910
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 53.5 bits (127), Expect = 9e-07
Identities = 72/304 (23%), Positives = 124/304 (40%), Gaps = 36/304 (11%)
Query: 449 VTLFWKPLSKLHANGKILFYNVVVENLDKPSSSE----LHSIPAPANSTKLILDR-CSYQ 503
V + W P N I Y++ E DK + E L +P ST L L Y
Sbjct: 631 VRVSWSPAED--HNAPIEKYDIEFE--DKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYT 686
Query: 504 ICVIANNSVGA---SPASVIVIS--ADPENKEVEEERIAGTEGGFSLSWKPQP-----GD 553
V A N G SP S V++ A PE V+ + ++WKP
Sbjct: 687 FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAP 746
Query: 554 VIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLL 613
+ Y V W Q G +Q + + + V +T F P Y+ ++ ++++
Sbjct: 747 QVQYRVQW--RPQGTRGPWQ-EQIVSDPFLVVSNTSTFVP---YEIKVQAVNSQGKGPEP 800
Query: 614 EKKTGYSQELAPSDNPHVL-VDTLTSHSFTLSWKDYSTESQPGFIQGYHV-YLKSKARQC 671
+ GYS E P P + ++ L S + + W+ G ++GY+V Y + +++
Sbjct: 801 QVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRK 860
Query: 672 HPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKV 731
H + + + D + + ++I+ L+P S Y + F G GP++ FT
Sbjct: 861 HSK--RHIHKD------HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFT-F 911
Query: 732 TTPD 735
+TP+
Sbjct: 912 STPE 915
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 53.5 bits (127), Expect = 9e-07
Identities = 72/304 (23%), Positives = 124/304 (40%), Gaps = 36/304 (11%)
Query: 449 VTLFWKPLSKLHANGKILFYNVVVENLDKPSSSE----LHSIPAPANSTKLILDR-CSYQ 503
V + W P N I Y++ E DK + E L +P ST L L Y
Sbjct: 631 VRVSWSPAED--HNAPIEKYDIEFE--DKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYT 686
Query: 504 ICVIANNSVGA---SPASVIVIS--ADPENKEVEEERIAGTEGGFSLSWKPQP-----GD 553
V A N G SP S V++ A PE V+ + ++WKP
Sbjct: 687 FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAP 746
Query: 554 VIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLL 613
+ Y V W Q G +Q + + + V +T F P Y+ ++ ++++
Sbjct: 747 QVQYRVQW--RPQGTRGPWQ-EQIVSDPFLVVSNTSTFVP---YEIKVQAVNSQGKGPEP 800
Query: 614 EKKTGYSQELAPSDNPHVL-VDTLTSHSFTLSWKDYSTESQPGFIQGYHV-YLKSKARQC 671
+ GYS E P P + ++ L S + + W+ G ++GY+V Y + +++
Sbjct: 801 QVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRK 860
Query: 672 HPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKV 731
H + + + D + + ++I+ L+P S Y + F G GP++ FT
Sbjct: 861 HSK--RHIHKD------HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFT-F 911
Query: 732 TTPD 735
+TP+
Sbjct: 912 STPE 915
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 51.6 bits (122), Expect = 4e-06
Identities = 75/316 (23%), Positives = 122/316 (38%), Gaps = 37/316 (11%)
Query: 373 EGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSE 432
E + Q+ V+ Y L +L+P T Y R + A S T ++ PS
Sbjct: 551 EDEDQQHKVTFDPTSSYTLEDLKPDTLY--RFQLAARSDMGVGVFTPTIEARTAQSTPSA 608
Query: 433 APDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSE--LHSIPAPA 490
P +++ + G+ TV + W P NG I Y+V E +D + I
Sbjct: 609 PPQ--KVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREH 666
Query: 491 NSTKLI-LDR-CSYQICVIANNSVGASPASVIVISADPEN------KEVEEERIAGTEGG 542
+S L+ L++ Y++ V A+ VG P S V+ E+ ++VE E + T
Sbjct: 667 SSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNST--A 724
Query: 543 FSLSWK-----PQPGDVIGYVVDW----------CDHTQDV-LGDFQWKNVGPNTTSTVI 586
+ WK Q G + GY V + QDV L + QW+ T I
Sbjct: 725 VHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTI 784
Query: 587 STDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWK 646
S P Y + +TK + K + P P +++ T ++ L W
Sbjct: 785 S--GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPG-RPTMMISTTAMNTALLQW- 840
Query: 647 DYSTESQPGFIQGYHV 662
+ + PG + GY +
Sbjct: 841 -HPPKELPGELLGYRL 855
Score = 40.4 bits (93), Expect = 0.008
Identities = 90/412 (21%), Positives = 142/412 (34%), Gaps = 66/412 (16%)
Query: 394 LEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHT-VTLF 452
LE TEY VR + E S T E PS P R V +EP N T V ++
Sbjct: 674 LEKWTEYRVWVRAH--TDVGPGPESSPVLVRTDEDVPSGPP---RKVEVEPLNSTAVHVY 728
Query: 453 WKPLSKLHANGKILFYNVVVENLDKPSSSELHSIP---------APANSTKL------IL 497
WK +G+I Y V L+ L I P S +
Sbjct: 729 WKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLT 788
Query: 498 DRCSYQICVIANNSVG----ASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQ--- 550
+Y + V A + G + P V A P + A L W P
Sbjct: 789 PETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA--LLQWHPPKEL 846
Query: 551 PGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIA 610
PG+++GY + +C + + + T T G Y FR+ + +
Sbjct: 847 PGELLGYRLQYCRADEARPNTIDFGKDDQHFTVT-----GLHKGTTYIFRLAAKNRAGLG 901
Query: 611 CLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQ 670
EK+ ++L ++ V LT+ + L+W + G I Y V +
Sbjct: 902 EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRD---- 957
Query: 671 CHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTK 730
++ E D + LKP++ Y+ + +TS G GP
Sbjct: 958 ---------INSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGSGP------ 998
Query: 731 VTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKSSI 782
++ + +M + + F V M L S W ++PD YKS++
Sbjct: 999 LSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLS-W-------EVPDSYKSAV 1042
Score = 34.3 bits (77), Expect = 0.59
Identities = 35/152 (23%), Positives = 57/152 (37%), Gaps = 16/152 (10%)
Query: 583 STVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPH-VLVDTLTSHSF 641
+T S P Y FR+ +++ E + E APS P V L++ +
Sbjct: 371 TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTM 430
Query: 642 TLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIV 701
+ W+ E G ++GY VY +R+ + K G V
Sbjct: 431 LVQWEP--PEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGL-------------LTTV 475
Query: 702 DNLKPESFYEFFITPFTSAGEGPSATFTKVTT 733
+L P Y + FT+ G+GP + +V T
Sbjct: 476 GSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT 507
Score = 33.5 bits (75), Expect = 1.0
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 384 KVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLE 443
K + + ++ L T Y+ R+ + + + E + T E PS P + L
Sbjct: 872 KDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE---KEIRTPEDLPSGFPQNLHVTGLT 928
Query: 444 PGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKL-ILDRCSY 502
T L W P NG+I+ Y VV +++ S EL +I T + +Y
Sbjct: 929 TS--TTELAWDPPVLAERNGRIISYTVVFRDIN--SQQELQNITTDTRFTLTGLKPDTTY 984
Query: 503 QICVIANNSVGASPASVIVISADPENKEVEEERI---AGTEGGFSLSWK 548
I V A S G+ P S + S ++V + A + LSW+
Sbjct: 985 DIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE 1033
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 50.8 bits (120), Expect = 6e-06
Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 35/252 (13%)
Query: 501 SYQICVIANNSVGASPAS-----VIVISADPENKEVEEERIAGTEGGFSLSWKP-----Q 550
+Y V+A NS+G S S + +++P+ E + ++WKP
Sbjct: 716 NYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 775
Query: 551 PGDVIGYVVDWCDHTQDVLGDFQWKNVG-PNTTSTVIS-TDAFRPGVRYDFRIYGLSTKR 608
G + Y V W GD +W +V N + ++S T F P Y ++ L+
Sbjct: 776 NGPGLQYKVSWRQKD----GDDEWTSVVVANVSKYIVSGTPTFVP---YLIKVQALNDMG 828
Query: 609 IACLLEKKTGYSQELAPSDNP-HVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVY---L 664
A G+S E P P +V V+ + S + W +S G +QGY +Y
Sbjct: 829 FAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKT 888
Query: 665 KSKARQCHPRFEKAVLS-DGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEG 723
+S +++ EK +L+ GS+ ++ L+P S Y + GEG
Sbjct: 889 QSSSKRNRRHIEKKILTFQGSKTHG-----------MLPGLEPFSHYTLNVRVVNGKGEG 937
Query: 724 PSATFTKVTTPD 735
P++ TP+
Sbjct: 938 PASPDRVFNTPE 949
Score = 41.2 bits (95), Expect = 0.005
Identities = 88/370 (23%), Positives = 129/370 (34%), Gaps = 55/370 (14%)
Query: 393 ELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLF 452
+L P Y RV ++ SE S Q + T + P + P + EP N +T
Sbjct: 710 KLSPYVNYSFRVMAVNSIGKSLPSEASEQ-YLTKASEPDKNPTAVEGLGSEPDNLVIT-- 766
Query: 453 WKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDR----CSYQICVIA 508
WKPL+ +NG L Y V K E S+ AN +K I+ Y I V A
Sbjct: 767 WKPLNGFESNGPGLQYKVSWR--QKDGDDEWTSV-VVANVSKYIVSGTPTFVPYLIKVQA 823
Query: 509 NNSVGASPASVIVISADPEN------KEVEEERIAGTEGGFSLSWKPQP-----GDVIGY 557
N +G +P +V+ E+ V + T + W P P G + GY
Sbjct: 824 LNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLA--EVHWDPVPLKSIRGHLQGY 881
Query: 558 VVDWCD----------HTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTK 607
+ + H + + FQ G T + + F Y + ++ K
Sbjct: 882 RIYYWKTQSSSKRNRRHIEKKILTFQ----GSKTHGMLPGLEPFS---HYTLNVRVVNGK 934
Query: 608 RIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSK 667
+ + E PS + + T S TL W P G K
Sbjct: 935 GEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEW------DPPSHPNGILTEYTLK 988
Query: 668 ARQCHPRFEKAVLSDGSECCKYKIDNPEEKA-LIVDNLKPESFYEFFITPFTSAGEGPSA 726
+ + E L D + P K + NL + Y+F+ TSAG G
Sbjct: 989 YQPINSTHELGPLVD--------LKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQI 1040
Query: 727 TFTKVTTPDE 736
T VTT DE
Sbjct: 1041 TEEAVTTVDE 1050
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 50.8 bits (120), Expect = 6e-06
Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 35/252 (13%)
Query: 501 SYQICVIANNSVGASPAS-----VIVISADPENKEVEEERIAGTEGGFSLSWKP-----Q 550
+Y V+A NS+G S S + +++P+ E + ++WKP
Sbjct: 700 NYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 759
Query: 551 PGDVIGYVVDWCDHTQDVLGDFQWKNVG-PNTTSTVIS-TDAFRPGVRYDFRIYGLSTKR 608
G + Y V W GD +W +V N + ++S T F P Y ++ L+
Sbjct: 760 NGPGLQYKVSWRQKD----GDDEWTSVVVANVSKYIVSGTPTFVP---YLIKVQALNDMG 812
Query: 609 IACLLEKKTGYSQELAPSDNP-HVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVY---L 664
A G+S E P P +V V+ + S + W +S G +QGY +Y
Sbjct: 813 FAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKT 872
Query: 665 KSKARQCHPRFEKAVLS-DGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEG 723
+S +++ EK +L+ GS+ ++ L+P S Y + GEG
Sbjct: 873 QSSSKRNRRHIEKKILTFQGSKTHG-----------MLPGLEPFSHYTLNVRVVNGKGEG 921
Query: 724 PSATFTKVTTPD 735
P++ TP+
Sbjct: 922 PASPDRVFNTPE 933
Score = 46.2 bits (108), Expect = 1e-04
Identities = 91/406 (22%), Positives = 144/406 (35%), Gaps = 65/406 (16%)
Query: 393 ELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLF 452
+L P Y RV ++ SE S Q + T + P + P + EP N +T
Sbjct: 694 KLSPYVNYSFRVMAVNSIGKSLPSEASEQ-YLTKASEPDKNPTAVEGLGSEPDNLVIT-- 750
Query: 453 WKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDR----CSYQICVIA 508
WKPL+ +NG L Y V K E S+ AN +K I+ Y I V A
Sbjct: 751 WKPLNGFESNGPGLQYKVSWR--QKDGDDEWTSV-VVANVSKYIVSGTPTFVPYLIKVQA 807
Query: 509 NNSVGASPASVIVISADPEN------KEVEEERIAGTEGGFSLSWKPQP-----GDVIGY 557
N +G +P +V+ E+ V + T + W P P G + GY
Sbjct: 808 LNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLA--EVHWDPVPLKSIRGHLQGY 865
Query: 558 VVDWCD----------HTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTK 607
+ + H + + FQ G T + + F Y + ++ K
Sbjct: 866 RIYYWKTQSSSKRNRRHIEKKILTFQ----GSKTHGMLPGLEPFS---HYTLNVRVVNGK 918
Query: 608 RIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSK 667
+ + E PS + + T S TL W P G K
Sbjct: 919 GEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEW------DPPSHPNGILTEYTLK 972
Query: 668 ARQCHPRFEKAVLSDGSECCKYKIDNPEEKA-LIVDNLKPESFYEFFITPFTSAGEGPSA 726
+ + E L D + P K + NL + Y+F+ TSAG G
Sbjct: 973 YQPINSTHELGPLVD--------LKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQI 1024
Query: 727 TFTKVTTPDE----------HSSMLIHILLPMVFCVLLIMVMCYLK 762
T VTT DE I ++ + +L+++++C+++
Sbjct: 1025 TEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIR 1070
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 50.4 bits (119), Expect = 8e-06
Identities = 66/288 (22%), Positives = 114/288 (39%), Gaps = 36/288 (12%)
Query: 461 ANGKILFYNVVVENLDKPSSSELHSIPAPANSTKL--ILDRCSYQICVIANNSVGASPA- 517
A G + Y V ++L + ++P A T + + Y+I V A S G
Sbjct: 928 APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987
Query: 518 ---SVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQW 574
+ +S D + +V+EE TE ++WKP PG V+ Y V + H + G
Sbjct: 988 TGDATTELSQDSKTLKVDEE----TENTMRVTWKPAPGKVVNYRVVYRPHGR---GKQMV 1040
Query: 575 KNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVD 634
V P TSTV+ +P YD + + K L + +G + S ++
Sbjct: 1041 AKVPPTVTSTVLK--RLQPQTTYDITVLPI-YKMGEGKLRQGSGTTASRFKSPR-NLKTS 1096
Query: 635 TLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNP 694
T SF ++W E PG ++GY V HP + L + + P
Sbjct: 1097 DPTMSSFRVTW-----EPAPGEVKGYKVTF-------HPTGDDRRLGE-------LVVGP 1137
Query: 695 EEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLI 742
+ ++++ L+ + Y+ + GE ++TT + + M I
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPI 1185
Score = 42.7 bits (99), Expect = 0.002
Identities = 62/290 (21%), Positives = 110/290 (37%), Gaps = 48/290 (16%)
Query: 443 EPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLIL----D 498
+P T+ L W A GK+ Y V + + E + ++T +L +
Sbjct: 824 DPTTSTMKLSWSG-----APGKVKQYLVTYTPV---AGGETQEVTVRGDTTNTVLQGLKE 875
Query: 499 RCSYQICVIANNSVGASPA-----SVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGD 553
Y + V A + GA A + + P++ ++ T+ W PG
Sbjct: 876 GTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDI----TDTSIGAYWTSAPGM 931
Query: 554 VIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLL 613
V GY V W DV D KN+ + T+I + +P +Y ++ +
Sbjct: 932 VRGYRVSWKSLYDDV--DTGEKNLPEDAIHTMI--ENLQPETKYRISVFATYSSGEG--- 984
Query: 614 EKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHP 673
E TG + D+ + VD T ++ ++WK PG + Y V + H
Sbjct: 985 EPLTGDATTELSQDSKTLKVDEETENTMRVTWK-----PAPGKVVNYRVVYRP-----HG 1034
Query: 674 RFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEG 723
R ++ V K+ P + ++ L+P++ Y+ + P GEG
Sbjct: 1035 RGKQMVA---------KVP-PTVTSTVLKRLQPQTTYDITVLPIYKMGEG 1074
Score = 42.0 bits (97), Expect = 0.003
Identities = 76/355 (21%), Positives = 130/355 (36%), Gaps = 54/355 (15%)
Query: 391 LSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAA-PSEAPDVWRIVSLEPGNHTV 449
L++L P TEY V+ + + + T E P P ++ + + T+
Sbjct: 1532 LTDLVPNTEYAVTVQAV-------LHDLTSEPVTVREVTLPLPRPQDLKLRDVT--HSTM 1582
Query: 450 TLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIAN 509
+FW+P+ GK+ Y V + ++ + S K + + Y + V A
Sbjct: 1583 NVFWEPVP-----GKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAV 1637
Query: 510 NSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWC-----DH 564
+ G SP + P + T GF +W DV Y + W D
Sbjct: 1638 HDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDK 1697
Query: 565 TQDVL-GD---FQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYS 620
+ +L GD ++N+ PNT V T + D I ++R +L +
Sbjct: 1698 METILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLI---GSERTLPILTTQ---- 1750
Query: 621 QELAPSDNPHVL-VDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAV 679
AP P L V TS+S T+ W S G +Q Y + + + + E+
Sbjct: 1751 ---APKSGPRNLQVYNATSNSLTVKWDPAS-----GRVQKYRITYQPSTGEGN---EQTT 1799
Query: 680 LSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTP 734
G + ++++ LKP++ Y ++ GEG T T P
Sbjct: 1800 TIGG-----------RQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 1843
Score = 34.3 bits (77), Expect = 0.59
Identities = 56/271 (20%), Positives = 99/271 (36%), Gaps = 61/271 (22%)
Query: 481 SELHSIPAPANSTKLI-------LDRCSYQ----ICVIANNSVGASPASVIVISADPENK 529
SEL +I +P T + R S++ IC+ + A V D
Sbjct: 582 SELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFS 641
Query: 530 EVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTD 589
EV T GF +W P +V Y + + ++ GD + V P ++++V+ +
Sbjct: 642 EV-------TSYGFKTNWSPAGENVFSYHITY----KEAAGDDEVTVVEPASSTSVVLS- 689
Query: 590 AFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNP--------HVLVDTLTSHSF 641
+ +P Y + E + G+S LA + ++ V T+ SF
Sbjct: 690 SLKPETLYLVNVTA----------EYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739
Query: 642 TLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIV 701
++W PG + Y + + A G E + P ++ +
Sbjct: 740 KITWTQ-----APGRVLRYRIIYRPVA--------------GGESREVTTP-PNQRRRTL 779
Query: 702 DNLKPESFYEFFITPFTSAGEGPSATFTKVT 732
+NL P++ YE + P +G G T T
Sbjct: 780 ENLIPDTKYEVSVIPEYFSGPGTPLTGNAAT 810
Score = 34.3 bits (77), Expect = 0.59
Identities = 77/351 (21%), Positives = 140/351 (39%), Gaps = 59/351 (16%)
Query: 374 GKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEA 433
GK ++ VS ++ L +L+P TEY+ V +S + L+
Sbjct: 1425 GKRQEFYVS-RMETSTVLKDLKPETEYVVNV----------YSVVEDEYSEPLKGTEKTL 1473
Query: 434 PDVWRIVSL---EPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPA 490
P +VSL + G T+ + W+P+ A G IL Y V + +P+ + +
Sbjct: 1474 PVP--VVSLNIYDVGPTTMHVQWQPVGG--ATGYILSYKPVKDT--EPTRPKEVRLGPTV 1527
Query: 491 NSTKL--ILDRCSYQICVIAN-NSVGASPASVIVISAD-PENKEVEEERIAGTEGGFSLS 546
N +L ++ Y + V A + + + P +V ++ P ++++ + T ++
Sbjct: 1528 NDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDV--THSTMNVF 1585
Query: 547 WKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLST 606
W+P PG V Y+V + +DV + V + TST + D F +Y +S
Sbjct: 1586 WEPVPGKVRKYIVRYKTPEEDV----KEVEVDRSETSTSLK-DLFSQ------TLYTVSV 1634
Query: 607 KRIACLLEKKTGYSQELA-PSDNP-HVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYL 664
+ E +QE P P ++ + +TS F +W +++ + Y +
Sbjct: 1635 SAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD-----VSLYRI-- 1687
Query: 665 KSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFIT 715
GS I N +E L+ +NL P + YE IT
Sbjct: 1688 -------------TWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSIT 1725
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 50.1 bits (118), Expect = 1e-05
Identities = 55/243 (22%), Positives = 104/243 (42%), Gaps = 27/243 (11%)
Query: 336 PFSVNFENVNATNAIMTWKVHSIRN--NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSE 393
P + E + T+ +++W N+ + + HGE + ++I+ Y L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGE----EQRITIEPGTSYRLQG 574
Query: 394 LEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFW 453
L+P + Y R+ A S + + + T+++ PS P I P + ++ + W
Sbjct: 575 LKPNSLYYFRL--AARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSW 630
Query: 454 KPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDR----CSYQICVIAN 509
+P NG I Y++ +D + P+++TK +L++ Y+I V A+
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAH 690
Query: 510 NSVGASPASVIVISADPEN------KEVEEERIAGTEGGFSLSWK-----PQPGDVIGYV 558
VG P S+ V+ E+ ++VE E + T +SW+ Q G + GY
Sbjct: 691 TDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNST--SVKVSWRSPVPNKQHGQIRGYQ 748
Query: 559 VDW 561
V +
Sbjct: 749 VHY 751
Score = 44.3 bits (103), Expect = 6e-04
Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 16/152 (10%)
Query: 583 STVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPH-VLVDTLTSHSF 641
+T S P Y+FR+ ++ E + E APS P V L+S +
Sbjct: 375 TTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTI 434
Query: 642 TLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIV 701
+ WK+ E G IQGY VY Q + K ++D + +
Sbjct: 435 LVQWKE--PEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADS-------------QITTI 479
Query: 702 DNLKPESFYEFFITPFTSAGEGPSATFTKVTT 733
NL P+ Y + FTS G+GP ++ +V T
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 511
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 17/118 (14%)
Query: 620 SQELAPSDNPH-VLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVY---LKSKARQCHPRF 675
+ E PS P V V+ + S S +SW+ Q G I+GY V+ +++ + P
Sbjct: 706 TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765
Query: 676 EKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTT 733
+ +L+D + +I+ L+PE+ Y +T +T+ G+G + V+T
Sbjct: 766 KDVMLADAQD-------------MIISGLQPETSYSLTVTAYTTKGDGARSKPKLVST 810
Score = 38.1 bits (87), Expect = 0.041
Identities = 88/387 (22%), Positives = 138/387 (35%), Gaps = 50/387 (12%)
Query: 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNH 447
+Y L +LE TEY R+ + E T E PS P R V +E N
Sbjct: 671 KYLLEQLEKWTEY--RITVTAHTDVGPGPESLSVLIRTNEDVPSGPP---RKVEVEAVNS 725
Query: 448 T-VTLFWKPLSKLHANGKILFYNVVVENLD--KPSSSELHSIPAPANSTKLILD----RC 500
T V + W+ +G+I Y V ++ +P + A++ +I+
Sbjct: 726 TSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPET 785
Query: 501 SYQICVIANNSVG----ASPASVIVISADPENKEVEEERIAGTEGGFSL-SWKPQP---G 552
SY + V A + G + P V A P + I T+ +L W P G
Sbjct: 786 SYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLV---INHTQMNTALIQWHPPVDTFG 842
Query: 553 DVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDA---FRPGVRYDFRIYGLSTKRI 609
+ GY + + + L ++ + T+T I A FR R K I
Sbjct: 843 PLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEI 902
Query: 610 ACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKAR 669
+ E TG+ Q L TS S LSW+ + G I Y + +
Sbjct: 903 SIPEEVPTGFPQNLHSEGT--------TSTSVQLSWQPPVLAERNGIITKYTLLYRDINI 954
Query: 670 QCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFT 729
P + V P + + + LKP++ Y+ + TS G GP +
Sbjct: 955 PLLPMEQLIV--------------PADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSV 1000
Query: 730 KVTT--PDEHSSMLIHILLPMVFCVLL 754
+ T D+ + H+ M VLL
Sbjct: 1001 QFRTLPVDQVFAKNFHVKAVMKTSVLL 1027
Score = 36.6 bits (83), Expect = 0.12
Identities = 113/527 (21%), Positives = 192/527 (36%), Gaps = 61/527 (11%)
Query: 234 SKVLEEPKDFSCETEDFKTLHCTWD-PGTDTALGWSKQPSQSYTLF--ESFSGEKKLCTH 290
SK P+D SC + ++ +W P + G + S YT E + L
Sbjct: 607 SKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIP 666
Query: 291 KNWCNWQITQDSQET-YNFTLIAENYL--RKRSVNILFNLTHRVYLMNPFSVNFENVNAT 347
+ + + Q + T Y T+ A + S+++L V P V E VN+T
Sbjct: 667 SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNST 726
Query: 348 NAIMTW------KVH-SIRNNFTYLCQIELHGE--GKMMQYNVSIKVNGEYFLSELEPAT 398
+ ++W K H IR + ++E +GE G+ M +V + + +S L+P T
Sbjct: 727 SVKVSWRSPVPNKQHGQIRGYQVHYVRME-NGEPKGQPMLKDVMLADAQDMIISGLQPET 785
Query: 399 EYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSK 458
Y V + ++ L + P R+V +T + W P
Sbjct: 786 SYSLTVTA------YTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHP--P 837
Query: 459 LHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDR-CSYQICVIANNSVGASPA 517
+ G + Y + D + L + T + + SY + A N VG
Sbjct: 838 VDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEE 897
Query: 518 SVIVISADPENKEVEEERIAGTEGGFS----LSWKP-----QPGDVIGYVVDWCDHTQDV 568
V IS PE + +EG S LSW+P + G + Y + + D +
Sbjct: 898 MVKEISI-PEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPL 956
Query: 569 LGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDN 628
L + V +TT T+ +P YD ++ ++K + +
Sbjct: 957 L-PMEQLIVPADTTMTL---TGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFA 1012
Query: 629 PHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCK 688
+ V + S LSW+ + Y+ + K +L D + +
Sbjct: 1013 KNFHVKAVMKTSVLLSWE---------IPENYNSAMPFK-----------ILYDDGKMVE 1052
Query: 689 YKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPD 735
++D + LIV NLKPE Y F +T ++ G T T PD
Sbjct: 1053 -EVDGRATQKLIV-NLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPD 1097
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 48.5 bits (114), Expect = 3e-05
Identities = 47/209 (22%), Positives = 88/209 (42%), Gaps = 39/209 (18%)
Query: 545 LSWKPQP-----GDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDF 599
+SW+P P G ++GY V + + + + P TT ++ +A +Y
Sbjct: 637 VSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILL--EALEKWTQY-- 692
Query: 600 RIYGLSTKRIACLLEKKTGYSQELAP------SDNPH-----VLVDTLTSHSFTLSWKDY 648
RI + + G E +P D P V + L + + + W+
Sbjct: 693 --------RITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSP 744
Query: 649 STESQPGFIQGYHV-YLKSKARQCH--PRFEKAVLSDGSECCKYKIDNPEEKALIVDNLK 705
+ Q G I+GY V Y++ + + PR + +L+D +++ D+ E +++ NL+
Sbjct: 745 APGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADA----QWETDDTAEYEMVITNLQ 800
Query: 706 PESFYEFFITPFTSAGEG----PSATFTK 730
PE+ Y + +T G+G P TK
Sbjct: 801 PETAYSITVAAYTMKGDGARSKPKVVVTK 829
Score = 37.7 bits (86), Expect = 0.053
Identities = 45/197 (22%), Positives = 81/197 (41%), Gaps = 22/197 (11%)
Query: 539 TEGGFSLSWKP-QPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRY 597
T +++W P V YV+++ +QD G +Q K + T+T S P Y
Sbjct: 344 TATSITITWDSGNPDPVSYYVIEYKSKSQD--GPYQIKE---DITTTRYSIGGLSPNSEY 398
Query: 598 DFRIYGLSTKRIACLLEKKTGYSQELAPSDNP-HVLVDTLTSHSFTLSWKDYSTESQPGF 656
+ + +++ E + E AP+ P +V L++ + + W++ + G
Sbjct: 399 EIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPN--GL 456
Query: 657 IQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITP 716
I+GY VY + HP K+ +D + V +L + Y +
Sbjct: 457 IRGYRVYYTMEPE--HPV---------GNWQKHNVD--DSLLTTVGSLLEDETYTVRVLA 503
Query: 717 FTSAGEGPSATFTKVTT 733
FTS G+GP + +V T
Sbjct: 504 FTSVGDGPLSDPIQVKT 520
Score = 33.9 bits (76), Expect = 0.77
Identities = 36/158 (22%), Positives = 64/158 (40%), Gaps = 10/158 (6%)
Query: 502 YQICVIANNSVGASPASVIVISADPEN------KEVEEERIAGTEGGFSLSWKPQPGDVI 555
Y+I V A NS+G P S V++ E + V+ ++ T +P +I
Sbjct: 398 YEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLI 457
Query: 556 -GYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLE 614
GY V + + +G++Q NV + +TV + Y R+ ++ L +
Sbjct: 458 RGYRVYYTMEPEHPVGNWQKHNVDDSLLTTV---GSLLEDETYTVRVLAFTSVGDGPLSD 514
Query: 615 KKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTES 652
+Q+ P ++ + + S TLSW ES
Sbjct: 515 PIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQES 552
Score = 30.8 bits (68), Expect = 6.5
Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 8/84 (9%)
Query: 696 EKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLI 755
E AL + LKP++ Y+ + T G GP + P + + L + P F V +I
Sbjct: 992 ENALTLQGLKPDTAYDLQVRAHTRRGPGP------FSPPVRYRTFLRDQVSPKNFKVKMI 1045
Query: 756 MVMCYLKSQWIKETCYPDIPDPYK 779
M L S W Y + P PYK
Sbjct: 1046 MKTSVLLS-WEFPDNY-NSPTPYK 1067
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform
5 precursor [Homo sapiens]
Length = 1502
Score = 47.4 bits (111), Expect = 7e-05
Identities = 99/449 (22%), Positives = 180/449 (40%), Gaps = 60/449 (13%)
Query: 301 DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRN 360
D +++ N+T +A + L + + +T + P + AT+ +TW +
Sbjct: 290 DVRQSANYTCVAMSTLGV--IEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP 347
Query: 361 NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG 420
Y+ Q + ++ + + Y ++ L P ++Y RV ++ +
Sbjct: 348 VSYYIIQHKPKNSEELYK-EIDGVATTRYSVAGLSPYSDYEFRV--VAVNNIGRGPPSEP 404
Query: 421 QNFTTLEAAPSEAP-DVW-RIVSLEPGNHTVTLFWKPLSKLHANGKILFYNV--VVENLD 476
T E APS AP DV R++S + T+ + WK + NG+I Y V ++
Sbjct: 405 VLTQTSEQAPSSAPRDVQARMLS----STTILVQWKEPEE--PNGQIQGYRVYYTMDPTQ 458
Query: 477 KPSSSELHSIPAPANSTKL--ILDRCSYQICVIANNSVGASPASVIV-------ISADPE 527
++ H++ A + T + ++ + +Y + V+A S+G P S + + P
Sbjct: 459 HVNNWMKHNV-ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPL 517
Query: 528 NKEVEEERIAGTEGGFSLSWKPQPGDVIG-YVVDWCDHTQDVLGDFQWKNVGPNTTSTVI 586
N + E E +E LSW P D I Y + + D G+ Q + P T+ +
Sbjct: 518 NFKAEPE----SETSILLSWTPPRSDTIANYELVYKDGEH---GEEQRITIEPGTSYRL- 569
Query: 587 STDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWK 646
+P Y FR+ S + + + + + + + N HV TS LSW+
Sbjct: 570 --QGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTS--VLLSWE 625
Query: 647 DYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKP 706
+ Y+ + K +L D + + ++D + LIV NLKP
Sbjct: 626 ---------IPENYNSAMPFK-----------ILYDDGKMVE-EVDGRATQKLIV-NLKP 663
Query: 707 ESFYEFFITPFTSAGEGPSATFTKVTTPD 735
E Y F +T ++ G T T PD
Sbjct: 664 EKSYSFVLTNRGNSAGGLQHRVTAKTAPD 692
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform
4 precursor [Homo sapiens]
Length = 1501
Score = 47.4 bits (111), Expect = 7e-05
Identities = 99/449 (22%), Positives = 180/449 (40%), Gaps = 60/449 (13%)
Query: 301 DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRN 360
D +++ N+T +A + L + + +T + P + AT+ +TW +
Sbjct: 293 DVRQSANYTCVAMSTLGV--IEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP 350
Query: 361 NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG 420
Y+ Q + ++ + + Y ++ L P ++Y RV ++ +
Sbjct: 351 VSYYIIQHKPKNSEELYK-EIDGVATTRYSVAGLSPYSDYEFRV--VAVNNIGRGPPSEP 407
Query: 421 QNFTTLEAAPSEAP-DVW-RIVSLEPGNHTVTLFWKPLSKLHANGKILFYNV--VVENLD 476
T E APS AP DV R++S + T+ + WK + NG+I Y V ++
Sbjct: 408 VLTQTSEQAPSSAPRDVQARMLS----STTILVQWKEPEE--PNGQIQGYRVYYTMDPTQ 461
Query: 477 KPSSSELHSIPAPANSTKL--ILDRCSYQICVIANNSVGASPASVIV-------ISADPE 527
++ H++ A + T + ++ + +Y + V+A S+G P S + + P
Sbjct: 462 HVNNWMKHNV-ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPL 520
Query: 528 NKEVEEERIAGTEGGFSLSWKPQPGDVIG-YVVDWCDHTQDVLGDFQWKNVGPNTTSTVI 586
N + E E +E LSW P D I Y + + D G+ Q + P T+ +
Sbjct: 521 NFKAEPE----SETSILLSWTPPRSDTIANYELVYKDGEH---GEEQRITIEPGTSYRL- 572
Query: 587 STDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWK 646
+P Y FR+ S + + + + + + + N HV TS LSW+
Sbjct: 573 --QGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTS--VLLSWE 628
Query: 647 DYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKP 706
+ Y+ + K +L D + + ++D + LIV NLKP
Sbjct: 629 ---------IPENYNSAMPFK-----------ILYDDGKMVE-EVDGRATQKLIV-NLKP 666
Query: 707 ESFYEFFITPFTSAGEGPSATFTKVTTPD 735
E Y F +T ++ G T T PD
Sbjct: 667 EKSYSFVLTNRGNSAGGLQHRVTAKTAPD 695
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,791,824
Number of Sequences: 37866
Number of extensions: 1924220
Number of successful extensions: 5238
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 4586
Number of HSP's gapped (non-prelim): 648
length of query: 979
length of database: 18,247,518
effective HSP length: 112
effective length of query: 867
effective length of database: 14,006,526
effective search space: 12143658042
effective search space used: 12143658042
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.